Sample records for handling equipment mhe

  1. Webinar August 11: Analysis Using Fuel Cell MHE for Shaving Peak Building

    Science.gov Websites

    ;Analysis Using Fuel Cell Material Handling Equipment (MHE) for Shaving Peak Building Energy" on offset grid charges associated with peak facility demands. The analyzed scenarios will focus on how the alternative peak-shaving apparatus. View the past webinar. -Sara Havig

  2. Early Fuel Cell Market Demonstration Composite Data Products | Hydrogen and

    Science.gov Websites

    demonstrations. Material Handling Equipment Demonstrations Cost of Ownership MHE Total Cost of Ownership, CDP MHE 58, 3/29/2012 MHE Total Cost Sensitivity, CDP MHE 59, 3/29/2012 MHE Intensive Deployment Total Cost , CDP MHE 60, 3/29/2012 General and Capital Cost Inputs for Class I/II MHE, CDP MHE 64a, 3/29/2012

  3. HAND TRUCK FOR HANDLING EQUIPMENT

    DOEpatents

    King, D.W.

    1959-02-24

    A truck is described for the handling of large and relatively heavy pieces of equipment and particularly for the handling of ion source units for use in calutrons. The truck includes a chassis and a frame pivoted to the chassis so as to be operable to swing in the manner of a boom. The frame has spaced members so arranged that the device to be handled can be suspended between or passed between these spaced members and also rotated with respect to the frame when the device is secured to the spaced members.

  4. 40 CFR 82.36 - Approved refrigerant handling equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Approved refrigerant handling equipment. (a)(1) Refrigerant recycling equipment must be certified by the...) Recovery/Recycling Equipment and Recovery/Recycling/Recharging for Mobile Air-Conditioning Systems. (5... Recycling Equipment Intended for Use with both CFC-12 and HFC-134a, Recommended Service Procedure for the...

  5. 40 CFR 82.36 - Approved refrigerant handling equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Approved refrigerant handling equipment. (a)(1) Refrigerant recycling equipment must be certified by the...) Recovery/Recycling Equipment and Recovery/Recycling/Recharging for Mobile Air-Conditioning Systems. (5... Recycling Equipment Intended for Use with both CFC-12 and HFC-134a, Recommended Service Procedure for the...

  6. 40 CFR 82.36 - Approved refrigerant handling equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Approved refrigerant handling equipment. (a)(1) Refrigerant recycling equipment must be certified by the...) Recovery/Recycling Equipment and Recovery/Recycling/Recharging for Mobile Air-Conditioning Systems. (5... Recycling Equipment Intended for Use with both CFC-12 and HFC-134a, Recommended Service Procedure for the...

  7. 40 CFR 82.36 - Approved refrigerant handling equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Approved refrigerant handling equipment. (a)(1) Refrigerant recycling equipment must be certified by the...) Recovery/Recycling Equipment and Recovery/Recycling/Recharging for Mobile Air-Conditioning Systems. (5... Recycling Equipment Intended for Use with both CFC-12 and HFC-134a, Recommended Service Procedure for the...

  8. 40 CFR 82.36 - Approved refrigerant handling equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Approved refrigerant handling equipment. (a)(1) Refrigerant recycling equipment must be certified by the...) Recovery/Recycling Equipment and Recovery/Recycling/Recharging for Mobile Air-Conditioning Systems. (5... Recycling Equipment Intended for Use with both CFC-12 and HFC-134a, Recommended Service Procedure for the...

  9. Standards for material handling and facilities equipment proofload testing

    NASA Technical Reports Server (NTRS)

    Bonn, S. P.

    1970-01-01

    Document provides information on verifying the safety of material handling and facilities equipment /MH/FE/, ranging from monorail systems to ladders and non-powered mobile equipment. Seven catagories of MH/FE equipment are defined.

  10. 49 CFR 176.192 - Cargo handling equipment for freight containers carrying Class 1 (explosive) materials.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 2 2014-10-01 2014-10-01 false Cargo handling equipment for freight containers...) Materials Handling Class 1 (explosive) Materials in Port § 176.192 Cargo handling equipment for freight containers carrying Class 1 (explosive) materials. (a) Except in an emergency, only cargo handling equipment...

  11. 49 CFR 176.192 - Cargo handling equipment for freight containers carrying Class 1 (explosive) materials.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Cargo handling equipment for freight containers...) Materials Handling Class 1 (explosive) Materials in Port § 176.192 Cargo handling equipment for freight containers carrying Class 1 (explosive) materials. (a) Except in an emergency, only cargo handling equipment...

  12. 49 CFR 176.192 - Cargo handling equipment for freight containers carrying Class 1 (explosive) materials.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 2 2011-10-01 2011-10-01 false Cargo handling equipment for freight containers...) Materials Handling Class 1 (explosive) Materials in Port § 176.192 Cargo handling equipment for freight containers carrying Class 1 (explosive) materials. (a) Except in an emergency, only cargo handling equipment...

  13. 49 CFR 176.192 - Cargo handling equipment for freight containers carrying Class 1 (explosive) materials.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false Cargo handling equipment for freight containers...) Materials Handling Class 1 (explosive) Materials in Port § 176.192 Cargo handling equipment for freight containers carrying Class 1 (explosive) materials. (a) Except in an emergency, only cargo handling equipment...

  14. 49 CFR 176.192 - Cargo handling equipment for freight containers carrying Class 1 (explosive) materials.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 2 2012-10-01 2012-10-01 false Cargo handling equipment for freight containers...) Materials Handling Class 1 (explosive) Materials in Port § 176.192 Cargo handling equipment for freight containers carrying Class 1 (explosive) materials. (a) Except in an emergency, only cargo handling equipment...

  15. 30 CFR 75.818 - Use of insulated cable handling equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... personal protective equipment capable of providing protection against shock hazard must be used to prevent... protective equipment must— (1) Have a voltage rating of at least Class 1 (7,500 volts) that meets or exceeds... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Use of insulated cable handling equipment. 75...

  16. 30 CFR 75.818 - Use of insulated cable handling equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... personal protective equipment capable of providing protection against shock hazard must be used to prevent... protective equipment must— (1) Have a voltage rating of at least Class 1 (7,500 volts) that meets or exceeds... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Use of insulated cable handling equipment. 75...

  17. 48 CFR 908.7112 - Materials handling equipment replacement standards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Materials handling equipment replacement standards. 908.7112 Section 908.7112 Federal Acquisition Regulations System DEPARTMENT OF ENERGY COMPETITION ACQUISITION PLANNING REQUIRED SOURCES OF SUPPLIES AND SERVICES Acquisition of...

  18. 30 CFR 250.108 - What requirements must I follow for cranes and other material-handling equipment?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... other material-handling equipment? 250.108 Section 250.108 Mineral Resources BUREAU OF SAFETY AND... material-handling equipment? (a) All cranes installed on fixed platforms must be operated in accordance... Cranes, API RP 2D (as incorporated by reference in § 250.198). (b) All cranes installed on fixed...

  19. 30 CFR 250.108 - What requirements must I follow for cranes and other material-handling equipment?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... other material-handling equipment? 250.108 Section 250.108 Mineral Resources BUREAU OF SAFETY AND... material-handling equipment? (a) All cranes installed on fixed platforms must be operated in accordance... Cranes, API RP 2D (as incorporated by reference in § 250.198). (b) All cranes installed on fixed...

  20. 30 CFR 250.108 - What requirements must I follow for cranes and other material-handling equipment?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... other material-handling equipment? 250.108 Section 250.108 Mineral Resources BUREAU OF SAFETY AND... material-handling equipment? (a) All cranes installed on fixed platforms must be operated in accordance... Cranes, API RP 2D (as incorporated by reference in § 250.198). (b) All cranes installed on fixed...

  1. Implications for patient safety in the use of safe patient handling equipment: a national survey.

    PubMed

    Elnitsky, Christine A; Lind, Jason D; Rugs, Deborah; Powell-Cope, Gail

    2014-12-01

    The prevalence of musculoskeletal injuries among nursing staff has been high due to patient handling and movement. Internationally, healthcare organizations are integrating technological equipment into patient handling and movement to improve safety. Although evidence shows that safe patient handling programs reduce work-related musculoskeletal injuries in nursing staff, it is not clear how safe these new programs are for patients. The objective of this study was to explore adverse patient events associated with safe patient handling programs and preventive approaches in US Veterans Affairs medical centers. The study surveyed a convenience sample of safe patient handling program managers from 51 US Department of Veterans Affairs medical centers to collect data on skin-related and fall-related adverse patient events. Both skin- and fall-related adverse patient events associated with safe patient handling occurred at VA Medical centers. Skin-related events included abrasions, contusions, pressure ulcers and lacerations. Fall-related events included sprains and strains, fractures, concussions and bleeding. Program managers described contextual factors in these adverse events and ways of preventing the events. The use of safe patient handling equipment can pose risks for patients. This study found that organizational factors, human factors and technology factors were associated with patient adverse events. The findings have implications for how nursing professionals can implement safe patient handling programs in ways that are safe for both staff and patients. Published by Elsevier Ltd.

  2. Emissions of NOx, particle mass and particle numbers from aircraft main engines, APU's and handling equipment at Copenhagen Airport

    NASA Astrophysics Data System (ADS)

    Winther, Morten; Kousgaard, Uffe; Ellermann, Thomas; Massling, Andreas; Nøjgaard, Jacob Klenø; Ketzel, Matthias

    2015-01-01

    This paper presents a detailed emission inventory for NOx, particle mass (PM) and particle numbers (PN) for aircraft main engines, APU's and handling equipment at Copenhagen Airport (CPH) based on time specific activity data and representative emission factors for the airport. The inventory has a high spatial resolution of 5 m × 5 m in order to be suited for further air quality dispersion calculations. Results are shown for the entire airport and for a section of the airport apron area ("inner apron") in focus. The methodology presented in this paper can be used to quantify the emissions from aircraft main engines, APU and handling equipment in other airports. For the entire airport, aircraft main engines is the largest source of fuel consumption (93%), NOx, (87%), PM (61%) and PN (95%). The calculated fuel consumption [NOx, PM, PN] shares for APU's and handling equipment are 5% [4%, 8%, 5%] and 2% [9%, 31%, 0%], respectively. At the inner apron area for handling equipment the share of fuel consumption [NOx, PM, PN] are 24% [63%, 75%, 2%], whereas APU and main engines shares are 43% [25%, 19%, 54%], and 33% [11%, 6%, 43%], respectively. The inner apron NOx and PM emission levels are high for handling equipment due to high emission factors for the diesel fuelled handling equipment and small for aircraft main engines due to small idle-power emission factors. Handling equipment is however a small PN source due to the low number based emission factors. Jet fuel sulphur-PM sensitivity calculations made in this study with the ICAO FOA3.0 method suggest that more than half of the PM emissions from aircraft main engines at CPH originate from the sulphur content of the fuel used at the airport. Aircraft main engine PN emissions are very sensitive to the underlying assumptions. Replacing this study's literature based average emission factors with "high" and "low" emission factors from the literature, the aircraft main engine PN emissions were estimated to change with a

  3. 77 FR 23117 - Rigging Equipment for Material Handling Construction Standard; Correction and Technical Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-18

    ...OSHA is correcting its sling standard for construction titled ``Rigging Equipment for Material Handling'' by removing the rated capacity tables and making minor, nonsubstantive revisions to the regulatory text.

  4. RiMINI - the influence of rifaximin on minimal hepatic encephalopathy (MHE) and on the intestinal microbiome in patients with liver cirrhosis: study protocol for a randomized controlled trial.

    PubMed

    Schulz, Christian; Schütte, Kerstin; Kropf, Siegfried; Schmitt, Friedhelm C; Vasapolli, Riccardo; Kliegis, Leon M; Riegger, Antonia; Malfertheiner, Peter

    2016-02-29

    Hepatic encephalopathy (HE) is a clinically significant complication of liver cirrhosis impacting on the patients' quality of life. Minimal hepatic encephalopathy (MHE) is diagnosed by psychometric tests, found in up to 80 % of patients with liver cirrhosis and carries a high risk of progression to overt HE. Continuous therapy with rifaximin in combination with lactulose significantly reduces the risk of overt HE, recurrence of HE and HE-related hospitalizations in randomized, double-blind, placebo-controlled clinical trials. Rifaximin is approved for the therapy of overt HE in Germany. Treatment with lactulose has been shown to improve cognitive functions in patients with liver cirrhosis. Data from prospective clinical trials comparing the efficacy of rifaximin alone against a combination of rifaximin and lactulose in the treatment of MHE are scarce. Changes in the microbiome of the upper and lower gastrointestinal tract as a result of therapy with rifaximin have not yet been addressed in clinical studies. RiMINI is a monocentric exploratory pilot study on 60 patients with MHE as assessed by critical flicker frequency (CFF). Additionally, visual evoked potentials' (VEP) testing, electroencephalography (EEG) and psychometric testing (NCT-A) will be carried out. Patients will be randomized to treatment either with rifaximin alone (550 mg twice daily (bid) continuously for a period of 3 months) or with rifaximin (550 mg bid continuously) in combination with lactulose (30-60 ml daily) for 3 months. An esophagogastroduodenoscopy (EGD) will be performed at baseline, at the end of treatment and 6 and 12 weeks after the end of treatment to obtain gastric and duodenal biopsies and aspirates. The samples will be analyzed for their content of specific bacterial taxae by applying next generation sequencing (NGS) after rRNA isolation to identify the microbiome of the stomach and duodenum, and of the gut, in patients with liver cirrhosis and MHE before and after therapy

  5. Fluid handling equipment: A compilation

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Devices and techniques used in fluid-handling and vacuum systems are described. Section 1 presents several articles on fluid lines and tubing. Section 2 describes a number of components such as valves, filters, and regulators. The last section contains descriptions of a number of innovative fluid-handling systems.

  6. STS-57 MS4 Voss, wearing goggles, handles SCG equipment on OV-105's middeck

    NASA Technical Reports Server (NTRS)

    1993-01-01

    STS-57 Mission Specialist 4 (MS4) Janice E. Voss, wearing goggles, handles plastic-wrapped Support of Crystal Growth (SCG) experiment equipment on the middeck of Endeavour, Orbiter Vehicle (OV) 105. Holding the SCG equipment over a portable light fixture, Voss determines the proper autoclave mixing protocols for the zeolite crystal growth experiment. The lighting fixture bracket is attached to the open airlock hatch in the foreground.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wheeler, Douglas; Ulsh, Michael

    The results of two Manufacturing Readiness Assessments of PEM fuel cell stacks and material handling equipment (MHE) and backup power (BUP) PEM fuel cell systems are given. Design modifications of fuel cell systems were made because the initial, 2008 designs did not fully meet the operational requirements of the markets. This situation indicates the 2008 risk elements were overstated.For 2010 BUP and MHE fuel cell systems, manufacturers had not reached the Low Rate Initial Production (LRIP) defined in the 2008 MRA Report at 1,000 units per year per manufacturer.For fuel cell stacks, LRIP was demonstrated by more than one manufacturer.Themore » federal tax incentive program has compensated for the initial high cost of fuel cell systems.The Balance-of-Plant (BOP) has not evolved as rapidly as the PEM fuel cell stack manufacturing readiness.The BOP in 2014 is as costly as the fuel cell stack for MHE applications.« less

  8. Overview of Remote Handling Equipment Used for the NPP A1 Decommissioning - 12141

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kravarik, K.; Medved, J.; Pekar, A.

    The first Czechoslovak NPP A1 was in operation from 1972 to 1977 and it was finally shutdown due to an accident (level 4 according to the INES). The presence of radioactive, toxic or hazardous materials limits personnel access to facilities and therefore it is necessary to use remote handling technologies for some most difficult characterization, retrieval, decontamination and dismantling tasks. The history of remote handling technologies utilization started in nineties when the spent nuclear fuel, including those fuel assemblies damaged during the accident, was prepared for the transport to Russia. Subsequent significant development of remote handling equipment continued during implementationmore » of the NPP A1 decommissioning project - Stage I and ongoing Stage II. Company VUJE, Inc. is the general contractor for both mentioned stages of the decommissioning project. Various remote handling manipulators and robotics arms were developed and used. It includes remotely controlled vehicle manipulator MT-15 used for characterisation tasks in hostile and radioactive environment, special robust manipulator DENAR-41 used for the decontamination of underground storage tanks and multi-purposes robotics arms MT-80 and MT-80A developed for variety of decontamination and dismantling tasks. The heavy water evaporator facility dismantling is the current task performed remotely by robotics arm MT-80. The heavy water evaporator is located inside the main production building in the room No. 220 where loose surface contamination varies from 10 Bq/cm{sup 2} to 1x10{sup 3} Bq/cm{sup 2}, dose rate is up to 1.5 mGy/h and the feeding pipeline contained liquid RAW with high tritium content. Presented manipulators have been designed for broad range of decommissioning tasks. They are used for recognition, sampling, waste retrieval from large underground tanks, decontamination and dismantling of technological equipments. Each of the mentioned fields claims specific requirements on design

  9. U.S. Department of Energy-Funded Performance Validation of Fuel Cell Material Handling Equipment (Presentation)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kurtz, J.; Sprik, S.; Ramsden, T.

    2013-11-01

    This webinar presentation to the UK Hydrogen and Fuel Cell Association summarizes how the U.S. Department of Energy is enabling early fuel cell markets; describes objectives of the National Fuel Cell Technology Evaluation Center; and presents performance status of fuel cell material handling equipment.

  10. 78 FR 70326 - Rigging Equipment for Material Handling; Extension of the Office of Management and Budget's (OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-25

    ...OSHA solicits public comments concerning its proposal to extend the OMB approval of the information collection requirements contained in paragraphs (b)(1), (b)(6)(i), (b)(6)(ii), (c)(15)(ii), (e)(1)(i), (ii), and (iii) and (f)(2) of the Standard on Rigging Equipment for Material Handling (29 CFR 1926.251). These paragraphs require affixing identification tags or markings on rigging equipment, developing and maintaining inspection records, and retaining proof- testing certificates.

  11. High Level Waste Remote Handling Equipment in the Melter Cave Support Handling System at the Hanford Waste Treatment Plant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bardal, M.A.; Darwen, N.J.

    2008-07-01

    Cold war plutonium production led to extensive amounts of radioactive waste stored in tanks at the Department of Energy's (DOE) Hanford site. Bechtel National, Inc. is building the largest nuclear Waste Treatment Plant in the world located at the Department of Energy's Hanford site to immobilize the millions of gallons of radioactive waste. The site comprises five main facilities; Pretreatment, High Level Waste vitrification, Low Active Waste vitrification, an Analytical Lab and the Balance of Facilities. The pretreatment facilities will separate the high and low level waste. The high level waste will then proceed to the HLW facility for vitrification.more » Vitrification is a process of utilizing a melter to mix molten glass with radioactive waste to form a stable product for storage. The melter cave is designated as the High Level Waste Melter Cave Support Handling System (HSH). There are several key processes that occur in the HSH cell that are necessary for vitrification and include: feed preparation, mixing, pouring, cooling and all maintenance and repair of the process equipment. Due to the cell's high level radiation, remote handling equipment provided by PaR Systems, Inc. is required to install and remove all equipment in the HSH cell. The remote handling crane is composed of a bridge and trolley. The trolley supports a telescoping tube set that rigidly deploys a TR 4350 manipulator arm with seven degrees of freedom. A rotating, extending, and retracting slewing hoist is mounted to the bottom of the trolley and is centered about the telescoping tube set. Both the manipulator and slewer are unique to this cell. The slewer can reach into corners and the manipulator's cross pivoting wrist provides better operational dexterity and camera viewing angles at the end of the arm. Since the crane functions will be operated remotely, the entire cell and crane have been modeled with 3-D software. Model simulations have been used to confirm operational and maintenance

  12. 30 CFR 250.108 - What requirements must I follow for cranes and other material-handling equipment?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What requirements must I follow for cranes and... Performance Standards § 250.108 What requirements must I follow for cranes and other material-handling equipment? (a) All cranes installed on fixed platforms must be operated in accordance with American...

  13. Comparison of Customer Preference for Bulk Material Handling Equipment through Fuzzy-AHP Approach

    NASA Astrophysics Data System (ADS)

    Sen, Kingshuk; Ghosh, Surojit; Sarkar, Bijan

    2017-06-01

    In the present study, customer's perception has played one of the important roles for selection of the exact equipment out of available alternatives. The present study is dealt with the method of optimization of selection criteria of a material handling equipment, based on the technical specifications considered to be available at the user end. In this work, the needs of customers have been identified and prioritized, that lead to the selection of number of criteria, which have direct effect upon the performance of the equipment. To check the consistency of selection criteria, first of all an AHP based methodology is adopted with the identified criteria and available product categories, based upon which, the judgments of the users are defined to derive the priority scales. Such judgments expressed the relative strength or intensity of the impact of the elements of the hierarchy. Subsequently, all the alternatives have ranked for each identified criteria with subsequent constitution of weighted matrices. The same has been compared with the normalized values of approximate selling prices of the equipments to determine individual cost-benefit ratio. Based on the cost-benefit ratio, the equipment is ranked. With same conditions, the study is obtained again with a Fuzzy AHP concept, where a fuzzy linguistic approach has reduced the amount of uncertainty in decision making, caused by conventional AHP due to lack of deterministic approach. The priority vectors of category and criteria are determined separately and multiplied to obtain composite score. Subsequently, the average of fuzzy weights was determined and the preferences of equipment are ranked.

  14. 30 CFR 250.108 - What requirements must I follow for cranes and other material-handling equipment?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 2 2011-07-01 2011-07-01 false What requirements must I follow for cranes and... follow for cranes and other material-handling equipment? (a) All cranes installed on fixed platforms must... Maintenance of Offshore Cranes (API RP 2D), incorporated by reference as specified in 30 CFR 250.198. (b) All...

  15. The Army’s Use of Containerization for Unit Deployments

    DTIC Science & Technology

    1991-12-07

    Because of their lack of MHE, they may require a smaller container size, like the old CONEX, that can be either man -handled or moved with a 10-ton...equipment. As a general rule, a unit should not take additional containers that will serve only as storage facilities or workplaces in the wartime area of...seamen required to man the existing reserve vessels; provides the govemrnment access to a ’healthy, source of shipping vt.’saels versus relying totally on

  16. Farmers' use of personal protective equipment during handling of plant protection products: Determinants of implementation.

    PubMed

    Damalas, Christos A; Abdollahzadeh, Gholamhossein

    2016-11-15

    Understanding factors affecting the use of personal protective equipment (PPE) during handling of plant protection products (PPPs) is of major importance for the design of tailored interventions to minimize exposure among farmers. However, data regarding this issue are highly limited. Factors related to the use of PPE during handling of PPPs were explored in a survey of cotton farmers in northern Greece. Data were collected through face-to-face interviews with the farmers based on a questionnaire with structured items on the frequency of use of various personal protective devices during handling of PPPs. New evidence on patterns of PPE use and potential exposure of farmers to PPPs is provided. Most farmers (49.3%) showed potentially unsafe behaviour with respect to PPE use. Hat and boots were the most commonly used protective items during PPPs use, but most of the farmers surveyed reported low frequency of use for gloves, goggles, face mask, coveralls, and respirator. Especially the respirator was reported to be the least used PPE item amongst farmers. Farmers who perceived PPPs as harmful substances or those who had an episode of intoxication in the past reported more frequent use of several PPE items. Stepwise multiple regression analysis revealed that the variable episode of intoxication in the past exerted the strongest positive influence on PPE use, followed by the perception of PPPs being hazardous substances, upper secondary education, previous training on PPPs (i.e., spraying equipment, application parameters, risks to human health and environment, safety issues) and farm size under cultivation. Old age exerted a significant negative influence on PPE use, namely, elderly farmers tended not to use PPE. Strategies to maximize the protection of applicators of PPPs from hazardous exposures still require innovation to achieve increased effectiveness. Emphasis on lifelong training and education of farmers about hazards and risks of PPPs is crucial for changing

  17. 9 CFR 381.201 - Means of conveyance and equipment used in handling poultry products offered for entry to be...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... INSPECTION AND CERTIFICATION POULTRY PRODUCTS INSPECTION REGULATIONS Imported Poultry Products § 381.201... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Means of conveyance and equipment used in handling poultry products offered for entry to be maintained in sanitary condition. 381.201...

  18. Storage and handling of aviation fuels at airports

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1988-01-01

    This standard covers the basic principles for the design of fuel handling facilities and equipment at airports. It provides a reference for the planning and operation of aviation fuel handling facilities and associated equipment.

  19. Mooring and ground handling rigid airships

    NASA Technical Reports Server (NTRS)

    Walker, H., Jr.

    1975-01-01

    The problems of mooring and ground handling rigid airships are discussed. A brief history of Mooring and Ground Handling Rigid Airships from July 2, 1900 through September 1, 1939 is included. Also a brief history of ground handling developments with large U. S. Navy nonrigid airships between September 1, 1939 and August 31, 1962 is included wherein developed equipment and techniques appear applicable to future large rigid airships. Finally recommendations are made pertaining to equipment and procedures which appear desirable and feasible for future rigid airship programs.

  20. Ergonomics and patient handling.

    PubMed

    McCoskey, Kelsey L

    2007-11-01

    This study aimed to describe patient-handling demands in inpatient units during a 24-hour period at a military health care facility. A 1-day total population survey described the diverse nature and impact of patient-handling tasks relative to a variety of nursing care units, patient characteristics, and transfer equipment. Productivity baselines were established based on patient dependency, physical exertion, type of transfer, and time spent performing the transfer. Descriptions of the physiological effect of transfers on staff based on patient, transfer, and staff characteristics were developed. Nursing staff response to surveys demonstrated how patient-handling demands are impacted by the staff's physical exertion and level of patient dependency. The findings of this study describe the types of transfers occurring in these inpatient units and the physical exertion and time requirements for these transfers. This description may guide selection of the most appropriate and cost-effective patient-handling equipment required for specific units and patients.

  1. 29 CFR 1926.602 - Material handling equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    .... Brake systems for self-propelled rubber-tired off-highway equipment manufactured after January 1, 1972... Engineers Recommended Practices: Self-Propelled Scrapers SAE J319b-1971. Self-Propelled Graders SAE J236... condition. (ii) No employer shall permit earthmoving or compacting equipment which has an obstructed view to...

  2. 29 CFR 1926.602 - Material handling equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    .... Brake systems for self-propelled rubber-tired off-highway equipment manufactured after January 1, 1972... Engineers Recommended Practices: Self-Propelled Scrapers SAE J319b-1971. Self-Propelled Graders SAE J236... condition. (ii) No employer shall permit earthmoving or compacting equipment which has an obstructed view to...

  3. 29 CFR 1926.602 - Material handling equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    .... Brake systems for self-propelled rubber-tired off-highway equipment manufactured after January 1, 1972... Engineers Recommended Practices: Self-Propelled Scrapers SAE J319b-1971. Self-Propelled Graders SAE J236... condition. (ii) No employer shall permit earthmoving or compacting equipment which has an obstructed view to...

  4. Comparative analysis of numerical models of pipe handling equipment used in offshore drilling applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pawlus, Witold, E-mail: witold.p.pawlus@ieee.org; Ebbesen, Morten K.; Hansen, Michael R.

    Design of offshore drilling equipment is a task that involves not only analysis of strict machine specifications and safety requirements but also consideration of changeable weather conditions and harsh environment. These challenges call for a multidisciplinary approach and make the design process complex. Various modeling software products are currently available to aid design engineers in their effort to test and redesign equipment before it is manufactured. However, given the number of available modeling tools and methods, the choice of the proper modeling methodology becomes not obvious and – in some cases – troublesome. Therefore, we present a comparative analysis ofmore » two popular approaches used in modeling and simulation of mechanical systems: multibody and analytical modeling. A gripper arm of the offshore vertical pipe handling machine is selected as a case study for which both models are created. In contrast to some other works, the current paper shows verification of both systems by benchmarking their simulation results against each other. Such criteria as modeling effort and results accuracy are evaluated to assess which modeling strategy is the most suitable given its eventual application.« less

  5. A multi-component patient-handling intervention improves attitudes and behaviors for safe patient handling and reduces aggression experienced by nursing staff: A controlled before-after study.

    PubMed

    Risør, Bettina Wulff; Casper, Sven Dalgas; Andersen, Lars Louis; Sørensen, Jan

    2017-04-01

    This study evaluated an intervention for patient-handling equipment aimed to improve nursing staffs' use of patient handling equipment and improve their general health, reduce musculoskeletal problems, aggressive episodes, days of absence and work-related accidents. As a controlled before-after study, questionnaire data were collected at baseline and 12-month follow-up among nursing staff at intervention and control wards at two hospitals. At 12-month follow-up, the intervention group had more positive attitudes towards patient-handling equipment and increased use of specific patient-handling equipment. In addition, a lower proportion of nursing staff in the intervention group had experienced physically aggressive episodes. No significant change was observed in general health status, musculoskeletal problems, days of absence or work-related accidents. The intervention resulted in more positive attitudes and behaviours for safe patient-handling and less physically aggressive episodes. However, this did not translate into improved health of the staff during the 12-month study period. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. More Than 1,000 Fuel Cell Units Deployed Through DOE ARRA Funding (Fact Sheet)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    This NREL Hydrogen and Fuel Cell Technical Highlight describes how early market end users are operating 1,111 fuel cell units at 301 sites in 20 states with funding from the U.S. Department of Energy Fuel Cell Technologies Program and analysis by NREL. The American Recovery and Reinvestment Act (ARRA) funded the deployment of approximately 1,000 fuel cell systems in key early markets to accelerate the commercialization and deployment of fuel cells and fuel cell manufacturing, installation, maintenance, and support services. In support of the ARRA fuel cell deployment objectives, NREL analyzes and validates the technology in real-world applications, reports onmore » the technology status, and facilitates the development of fuel cell technologies, manufacturing, and operations in strategic markets-including material handling equipment, backup power, and stationary power-where fuel cells can compete with conventional technologies. NREL is validating hydrogen and fuel cell systems in real-world settings through data collection, analysis, and reporting. The fuel cell and infrastructure analysis provides an independent, third-party assessment that focuses on fuel cell system and hydrogen infrastructure performance, operation, maintenance, use, and safety. An objective of the ARRA fuel cell project-to deploy approximately 1,000 fuel cell systems in key early markets - has been met in two years. By the end of 2011, 504 material handling equipment (MHE) fuel cell units were operating at 8 facilities and 607 backup power fuel cell units were operating at 293 sites. MHE and backup power are two markets where fuel cells are capable of meeting the operating demands, and deployments can be leveraged to accelerate fuel cell commercialization.« less

  7. WASTE HANDLING BUILDING ELECTRICAL SYSTEM DESCRIPTION DOCUMENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    S.C. Khamamkar

    2000-06-23

    The Waste Handling Building Electrical System performs the function of receiving, distributing, transforming, monitoring, and controlling AC and DC power to all waste handling building electrical loads. The system distributes normal electrical power to support all loads that are within the Waste Handling Building (WHB). The system also generates and distributes emergency power to support designated emergency loads within the WHB within specified time limits. The system provides the capability to transfer between normal and emergency power. The system provides emergency power via independent and physically separated distribution feeds from the normal supply. The designated emergency electrical equipment will bemore » designed to operate during and after design basis events (DBEs). The system also provides lighting, grounding, and lightning protection for the Waste Handling Building. The system is located in the Waste Handling Building System. The system consists of a diesel generator, power distribution cables, transformers, switch gear, motor controllers, power panel boards, lighting panel boards, lighting equipment, lightning protection equipment, control cabling, and grounding system. Emergency power is generated with a diesel generator located in a QL-2 structure and connected to the QL-2 bus. The Waste Handling Building Electrical System distributes and controls primary power to acceptable industry standards, and with a dependability compatible with waste handling building reliability objectives for non-safety electrical loads. It also generates and distributes emergency power to the designated emergency loads. The Waste Handling Building Electrical System receives power from the Site Electrical Power System. The primary material handling power interfaces include the Carrier/Cask Handling System, Canister Transfer System, Assembly Transfer System, Waste Package Remediation System, and Disposal Container Handling Systems. The system interfaces with the MGR

  8. Safe patient handling perceptions and practices: a survey of acute care physical therapists.

    PubMed

    Olkowski, Brian F; Stolfi, Angela M

    2014-05-01

    Acute care physical therapists are at risk for developing work-related musculoskeletal disorders (WMSDs) due to manual patient handling. Safe patient handling (SPH) reduces WMSDs caused by manual handling. The purpose of this study was to describe the patient handling practices of acute care physical therapists and their perceptions regarding SPH. Additionally, this study determined whether an SPH program influences the patient handling practices and perceptions regarding SPH of acute care physical therapists. Subscribers to the electronic discussion board of American Physical Therapy Association's Acute Care Section were invited to complete a survey questionnaire. The majority of respondents used SPH equipment and practices (91.1%), were confident using SPH equipment and practices (93.8%), agreed that evidence supports the use of SPH equipment and practices (87.0%), and reported the use of SPH equipment and practices is feasible (92.2%). Respondents at a facility with an SPH program were more likely to use SPH equipment and practices, have received training in the use of SPH equipment and practices, agree that the use of SPH equipment and practices is feasible, and feel confident using SPH equipment and practices. The study might not reflect the perceptions and practices of the population of acute care physical therapists. Acute care physical therapists are trained to use SPH equipment and practices, use SPH equipment and practices, and have positive perceptions regarding SPH. Acute care physical therapists in a facility with an SPH program are more likely to use SPH equipment and practices, receive training in SPH equipment and practices, and have positive perceptions regarding SPH. Quasi-regulatory organizations should incorporate SPH programs into their evaluative standards.

  9. Llama handling and training.

    PubMed

    McGee, M

    1994-07-01

    This article offers insights into the relationship of llama owners to their animals and the role of veterinarians as part of the animal care team. The effect of human behavior and handling techniques on llama behavior and marketability are discussed. Progressive ideas for nonforceful llama handling equipment, procedures, and training ideas are outlined in detail. Included are specific training plans for routine herd management chores such as injections and toenail trimming. This article is useful for both veterinarians and llama owners.

  10. 29 CFR 1926.602 - Material handling equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Engineers J333a-1970, Operator Protection for Agricultural and Light Industrial Tractors. (ii) Seat belts... wheel tractors, bulldozers, off-highway trucks, graders, agricultural and industrial tractors, and... Society of Automotive Engineers, J386-1969, Seat Belts for Construction Equipment. Seat belts for...

  11. 29 CFR 1926.602 - Material handling equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Engineers J333a-1970, Operator Protection for Agricultural and Light Industrial Tractors. (ii) Seat belts... wheel tractors, bulldozers, off-highway trucks, graders, agricultural and industrial tractors, and... Society of Automotive Engineers, J386-1969, Seat Belts for Construction Equipment. Seat belts for...

  12. WASTE HANDLING BUILDING VENTILATION SYSTEM DESCRIPTION DOCUMENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    P.A. Kumar

    2000-06-21

    The Waste Handling Building Ventilation System provides heating, ventilation, and air conditioning (HVAC) for the contaminated, potentially contaminated, and uncontaminated areas of the Monitored Geologic Repository's (MGR) Waste Handling Building (WHB). In the uncontaminated areas, the non-confinement area ventilation system maintains the proper environmental conditions for equipment operation and personnel comfort. In the contaminated and potentially contaminated areas, in addition to maintaining the proper environmental conditions for equipment operation and personnel comfort, the contamination confinement area ventilation system directs potentially contaminated air away from personnel in the WHB and confines the contamination within high-efficiency particulate air (HEPA) filtration units. Themore » contamination confinement areas ventilation system creates airflow paths and pressure zones to minimize the potential for spreading contamination within the building. The contamination confinement ventilation system also protects the environment and the public by limiting airborne releases of radioactive or other hazardous contaminants from the WHB. The Waste Handling Building Ventilation System is designed to perform its safety functions under accident conditions and other Design Basis Events (DBEs) (such as earthquakes, tornadoes, fires, and loss of the primary electric power). Additional system design features (such as compartmentalization with independent subsystems) limit the potential for cross-contamination within the WHB. The system provides status of important system parameters and equipment operation, and provides audible and/or visual indication of off-normal conditions and equipment failures. The Waste Handling Building Ventilation System confines the radioactive and hazardous material within the building such that the release rates comply with regulatory limits. The system design, operations, and maintenance activities incorporate ALARA (as low as is

  13. Dazomet Fumigant Safe Handling Guide

    EPA Pesticide Factsheets

    Dazomet is the active ingredient in Basamid G soil fumigant pesticide. Wear personal protective equipment such as respirators when handling Basamid granules or making an application, mitigate exposures, and recognize signs of vapor inhalation.

  14. 49 CFR 232.111 - Train handling information.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... train crew taking charge of a train be informed of: (1) The total weight and length of the train, based... 49 Transportation 4 2010-10-01 2010-10-01 false Train handling information. 232.111 Section 232... TRAINS AND EQUIPMENT; END-OF-TRAIN DEVICES General Requirements § 232.111 Train handling information. (a...

  15. Employee and customer handling of nicotine-containing e-liquids in vape shops.

    PubMed

    Garcia, Robert; Allem, Jon Patrick; Baezconde-Garbanati, Lourdes; Unger, Jennifer Beth; Sussman, Steve

    2016-01-01

    Vape shops sell electronic cigarettes and related products such as e-liquids, which may contain nicotine. Direct contact with nicotine can lead to adverse health effects, and few regulations exist on how nicotine is handled in vape shops. This study examined how customers and employees come into contact with, and handle, nicotine-containing e-liquids in vape shops with the goal of informing potential future regulation of nicotine handling in vape shops. Data were collected from 77 vape shops in the Los Angeles basin. Characteristics of the shops were documented by employee interviews and in store observations. Data collection was focused on shops located in areas with high concentrations of communities of interest; 20 shops from African-American communities, 17 from Hispanic communities, 18 from Korean communities, and 22 from non-Hispanic White communities. Half of the vape shops allowed customers to sample e-liquids with nicotine. Most of the shops (83%) provided self-service sampling stations for customers. A majority of shop employees (72%) reported that spills of e-liquids containing nicotine had occurred in the past. While 64% of the shops provided safety equipment, only 34% provided equipment for proper nicotine handling. Furthermore, 62% of shop employees reported handling nicotine without gloves or other safety equipment. Regulation on the handling of nicotine by customers and vape shop employees is important to prevent unsafe practices and subsequent injury. The frequent occurrence of spills and limited availability of safety equipment in vape shops highlights the need for the creation and enforcement of regulations to protect employees and customers. Appropriate safety training and equipment should be provided to employees to prevent accidental exposure to nicotine. Information on ways to safely handle nicotine should be communicated to vape shop employees and customers.

  16. Employee and customer handling of nicotine-containing e-liquids in vape shops

    PubMed Central

    Garcia, Robert; Allem, Jon Patrick; Baezconde-Garbanati, Lourdes; Unger, Jennifer Beth; Sussman, Steve

    2017-01-01

    INTRODUCTION Vape shops sell electronic cigarettes and related products such as e-liquids, which may contain nicotine. Direct contact with nicotine can lead to adverse health effects, and few regulations exist on how nicotine is handled in vape shops. This study examined how customers and employees come into contact with, and handle, nicotine-containing e-liquids in vape shops with the goal of informing potential future regulation of nicotine handling in vape shops. METHODS Data were collected from 77 vape shops in the Los Angeles basin. Characteristics of the shops were documented by employee interviews and in store observations. Data collection was focused on shops located in areas with high concentrations of communities of interest; 20 shops from African-American communities, 17 from Hispanic communities, 18 from Korean communities, and 22 from non-Hispanic White communities. RESULTS Half of the vape shops allowed customers to sample e-liquids with nicotine. Most of the shops (83%) provided self-service sampling stations for customers. A majority of shop employees (72%) reported that spills of e-liquids containing nicotine had occurred in the past. While 64% of the shops provided safety equipment, only 34% provided equipment for proper nicotine handling. Furthermore, 62% of shop employees reported handling nicotine without gloves or other safety equipment. CONCLUSIONS Regulation on the handling of nicotine by customers and vape shop employees is important to prevent unsafe practices and subsequent injury. The frequent occurrence of spills and limited availability of safety equipment in vape shops highlights the need for the creation and enforcement of regulations to protect employees and customers. Appropriate safety training and equipment should be provided to employees to prevent accidental exposure to nicotine. Information on ways to safely handle nicotine should be communicated to vape shop employees and customers. PMID:28660255

  17. 30 CFR 57.12014 - Handling energized power cables.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Handling energized power cables. 57.12014... Electricity Surface and Underground § 57.12014 Handling energized power cables. Power cables energized to.... This does not prohibit pulling or dragging of cable by the equipment it powers when the cable is...

  18. 30 CFR 57.12014 - Handling energized power cables.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Handling energized power cables. 57.12014... Electricity Surface and Underground § 57.12014 Handling energized power cables. Power cables energized to.... This does not prohibit pulling or dragging of cable by the equipment it powers when the cable is...

  19. 30 CFR 57.12014 - Handling energized power cables.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Handling energized power cables. 57.12014... Electricity Surface and Underground § 57.12014 Handling energized power cables. Power cables energized to.... This does not prohibit pulling or dragging of cable by the equipment it powers when the cable is...

  20. 30 CFR 57.12014 - Handling energized power cables.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Handling energized power cables. 57.12014... Electricity Surface and Underground § 57.12014 Handling energized power cables. Power cables energized to.... This does not prohibit pulling or dragging of cable by the equipment it powers when the cable is...

  1. 30 CFR 57.12014 - Handling energized power cables.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Handling energized power cables. 57.12014... Electricity Surface and Underground § 57.12014 Handling energized power cables. Power cables energized to.... This does not prohibit pulling or dragging of cable by the equipment it powers when the cable is...

  2. Spent fuel cask handling at an operating nuclear power plant

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pal, A.C.

    1988-01-01

    The importance of spent fuel handling at operating nuclear power plants cannot be overstated. Because of its highly radioactive nature, however, spent fuel must be handled in thick, lead-lined containers or casks. Thus, all casks for spent fuel handling are heavy loads by the US Nuclear Regulatory Commission's definition, and any load-drop must be evaluated for its potential to damage safety-related equipment. Nuclear Regulatory Guide NUREG-0612 prescribes the regulatory requirements of alternative heavy-load-handling methodologies such as (a) by providing cranes that meet the requirements of NUREG-0554, which shall be called the soft path, or (b) by providing protective devices atmore » all postulated load-drop areas to prevent any damage to safety-related equipment, which shall be called the hard path. The work reported in this paper relates to cask handling at New York Power Authority's James A. FitzPatrick (JAF) plant.« less

  3. 33 CFR 127.601 - Fire equipment: General.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) WATERFRONT FACILITIES WATERFRONT FACILITIES HANDLING LIQUEFIED NATURAL GAS AND LIQUEFIED HAZARDOUS GAS Waterfront Facilities Handling Liquefied Natural Gas Firefighting § 127.601 Fire equipment: General. (a) Fire... Laboratories, Inc., the Factory Mutual Research Corp., or the Coast Guard. ...

  4. 33 CFR 127.601 - Fire equipment: General.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) WATERFRONT FACILITIES WATERFRONT FACILITIES HANDLING LIQUEFIED NATURAL GAS AND LIQUEFIED HAZARDOUS GAS Waterfront Facilities Handling Liquefied Natural Gas Firefighting § 127.601 Fire equipment: General. (a) Fire... Laboratories, Inc., the Factory Mutual Research Corp., or the Coast Guard. ...

  5. Effects of the European Community directive on lifting and handling practice.

    PubMed

    Docker, S M

    1993-07-01

    The new legislation on lifting and handling requires the application of ergonomic principles to manual handling operations. A written assessment is required for all unavoidable manual handling operations which involve the risk of injury to employees. Employers are now expected to provide equipment to enable staff to avoid lifting heavy loads.

  6. Ground Handling of Batteries at Test and Launch-site Facilities

    NASA Technical Reports Server (NTRS)

    Jeevarajan, Judith A.; Hohl, Alan R.

    2008-01-01

    Ground handling of flight as well as engineering batteries at test facilities and launch-site facilities is a safety critical process. Test equipment interfacing with the batteries should have the required controls to prevent a hazardous failure of the batteries. Test equipment failures should not induce catastrophic failures on the batteries. Transportation requirements for batteries should also be taken into consideration for safe transportation. This viewgraph presentation includes information on the safe handling of batteries for ground processing at test facilities as well as launch-site facilities.

  7. 29 CFR 1926.605 - Marine operations and equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 8 2011-07-01 2011-07-01 false Marine operations and equipment. 1926.605 Section 1926.605 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION... Equipment, and Marine Operations § 1926.605 Marine operations and equipment. (a) Material handling...

  8. 29 CFR 1926.605 - Marine operations and equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 8 2014-07-01 2014-07-01 false Marine operations and equipment. 1926.605 Section 1926.605 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION... Equipment, and Marine Operations § 1926.605 Marine operations and equipment. (a) Material handling...

  9. 29 CFR 1926.605 - Marine operations and equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 8 2012-07-01 2012-07-01 false Marine operations and equipment. 1926.605 Section 1926.605 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION... Equipment, and Marine Operations § 1926.605 Marine operations and equipment. (a) Material handling...

  10. 29 CFR 1926.605 - Marine operations and equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 8 2013-07-01 2013-07-01 false Marine operations and equipment. 1926.605 Section 1926.605 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION... Equipment, and Marine Operations § 1926.605 Marine operations and equipment. (a) Material handling...

  11. Liquid class predictor for liquid handling of complex mixtures

    DOEpatents

    Seglke, Brent W [San Ramon, CA; Lekin, Timothy P [Livermore, CA

    2008-12-09

    A method of establishing liquid classes of complex mixtures for liquid handling equipment. The mixtures are composed of components and the equipment has equipment parameters. The first step comprises preparing a response curve for the components. The next step comprises using the response curve to prepare a response indicator for the mixtures. The next step comprises deriving a model that relates the components and the mixtures to establish the liquid classes.

  12. Musculoskeletal injuries resulting from patient handling tasks among hospital workers.

    PubMed

    Pompeii, Lisa A; Lipscomb, Hester J; Schoenfisch, Ashley L; Dement, John M

    2009-07-01

    The purpose of this study was to evaluate musculoskeletal injuries and disorders resulting from patient handling prior to the implementation of a "minimal manual lift" policy at a large tertiary care medical center. We sought to define the circumstances surrounding patient handling injuries and to identify potential preventive measures. Human resources data were used to define the cohort and their time at work. Workers' compensation records (1997-2003) were utilized to identify work-related musculoskeletal claims, while the workers' description of injury was used to identify those that resulted from patient handling. Adjusted rate ratios were generated using Poisson regression. One-third (n = 876) of all musculoskeletal injuries resulted from patient handling activities. Most (83%) of the injury burden was incurred by inpatient nurses, nurses' aides and radiology technicians, while injury rates were highest for nurses' aides (8.8/100 full-time equivalent, FTEs) and smaller workgroups including emergency medical technicians (10.3/100 FTEs), patient transporters (4.3/100 FTEs), operating room technicians (3.1/100 FTEs), and morgue technicians (2.2/100 FTEs). Forty percent of injuries due to lifting/transferring patients may have been prevented through the use of mechanical lift equipment, while 32% of injuries resulting from repositioning/turning patients, pulling patients up in bed, or catching falling patients may not have been prevented by the use of lift equipment. The use of mechanical lift equipment could significantly reduce the risk of some patient handling injuries but additional interventions need to be considered that address other patient handling tasks. Smaller high-risk workgroups should not be neglected in prevention efforts.

  13. Communications techniques and equipment: A compilation

    NASA Technical Reports Server (NTRS)

    1975-01-01

    This Compilation is devoted to equipment and techniques in the field of communications. It contains three sections. One section is on telemetry, including articles on radar and antennas. The second section describes techniques and equipment for coding and handling data. The third and final section includes descriptions of amplifiers, receivers, and other communications subsystems.

  14. 30 CFR 57.16017 - Hoisting heavy equipment or material.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Hoisting heavy equipment or material. 57.16017... Storage and Handling § 57.16017 Hoisting heavy equipment or material. Where the stretching or contraction... conveyances at shaft landings before heavy equipment or material is loaded or unloaded. ...

  15. Wireless "Jump" Starts for Partly Disabled Equipment

    NASA Technical Reports Server (NTRS)

    Castle, K. D.

    1986-01-01

    Equipment activated when normal remote starting does not work Beam from nearby station first carries raw energy and then subsystemactivating signals to equipment crippled by discharged storage batteries. Operators start up equipment without approaching it under hazardous conditions. Potential terrestrial applications for scheme include starting of robots on such remotely-controlled hazardous tasks as handling of explosives or retrieval or deposition of objects in hostile environments.

  16. 29 CFR 1926.953 - Material handling.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Material handling. (a) Unloading. Prior to unloading steel, poles, cross arms and similar material, the.... During framing operations, employees shall not work under a pole or a structure suspended by a crane, A-frame or similar equipment unless the pole or structure is adequately supported. (g) Attaching the load...

  17. 29 CFR 1926.953 - Material handling.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Material handling. (a) Unloading. Prior to unloading steel, poles, cross arms and similar material, the.... During framing operations, employees shall not work under a pole or a structure suspended by a crane, A-frame or similar equipment unless the pole or structure is adequately supported. (g) Attaching the load...

  18. 29 CFR 1926.953 - Material handling.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Material handling. (a) Unloading. Prior to unloading steel, poles, cross arms and similar material, the.... During framing operations, employees shall not work under a pole or a structure suspended by a crane, A-frame or similar equipment unless the pole or structure is adequately supported. (g) Attaching the load...

  19. CARRIER PREPARATION BUILDING MATERIALS HANDLING SYSTEM DESCRIPTION DOCUMENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    E.F. Loros

    2000-06-28

    The Carrier Preparation Building Materials Handling System receives rail and truck shipping casks from the Carrier/Cask Transport System, and inspects and prepares the shipping casks for return to the Carrier/Cask Transport System. Carrier preparation operations for carriers/casks received at the surface repository include performing a radiation survey of the carrier and cask, removing/retracting the personnel barrier, measuring the cask temperature, removing/retracting the impact limiters, removing the cask tie-downs (if any), and installing the cask trunnions (if any). The shipping operations for carriers/casks leaving the surface repository include removing the cask trunnions (if any), installing the cask tie-downs (if any), installingmore » the impact limiters, performing a radiation survey of the cask, and installing the personnel barrier. There are four parallel carrier/cask preparation lines installed in the Carrier Preparation Building with two preparation bays in each line, each of which can accommodate carrier/cask shipping and receiving. The lines are operated concurrently to handle the waste shipping throughputs and to allow system maintenance operations. One remotely operated overhead bridge crane and one remotely operated manipulator is provided for each pair of carrier/cask preparation lines servicing four preparation bays. Remotely operated support equipment includes a manipulator and tooling and fixtures for removing and installing personnel barriers, impact limiters, cask trunnions, and cask tie-downs. Remote handling equipment is designed to facilitate maintenance, dose reduction, and replacement of interchangeable components where appropriate. Semi-automatic, manual, and backup control methods support normal, abnormal, and recovery operations. Laydown areas and equipment are included as required for transportation system components (e.g., personnel barriers and impact limiters), fixtures, and tooling to support abnormal and recovery operations

  20. Analysis of Material Handling Safety in Construction Sites and Countermeasures for Effective Enhancement

    PubMed Central

    Anil Kumar, C. N.; Sakthivel, M.; Elangovan, R. K.; Arularasu, M.

    2015-01-01

    One of many hazardous workplaces includes the construction sites as they involve several dangerous tasks. Many studies have revealed that material handling equipment is a major cause of accidents at these sites. Though safety measures are being followed and monitored continuously, accident rates are still high as either workers are unaware of hazards or the safety regulations are not being strictly followed. This paper analyses the safety management systems at construction sites through means of questionnaire surveys with employees, specifically referring to safety of material handling equipment. Based on results of the questionnaire surveys, two construction sites were selected for a safety education program targeting worker safety related to material handling equipment. Knowledge levels of the workers were gathered before and after the program and results obtained were subjected to a t-test analysis to mark significance level of the conducted safety education program. PMID:26446572

  1. CARRIER/CASK HANDLING SYSTEM DESCRIPTION DOCUMENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    E.F. Loros

    2000-06-23

    The Carrier/Cask Handling System receives casks on railcars and legal-weight trucks (LWTs) (transporters) that transport loaded casks and empty overpacks to the Monitored Geologic Repository (MGR) from the Carrier/Cask Transport System. Casks that come to the MGR on heavy-haul trucks (HHTs) are transferred onto railcars before being brought into the Carrier/Cask Handling System. The system is the interfacing system between the railcars and LWTs and the Assembly Transfer System (ATS) and Canister Transfer System (CTS). The Carrier/Cask Handling System removes loaded casks from the cask transporters and transfers the casks to a transfer cart for either the ATS or CTS,more » as appropriate, based on cask contents. The Carrier/Cask Handling System receives the returned empty casks from the ATS and CTS and mounts the casks back onto the transporters for reshipment. If necessary, the Carrier/Cask Handling System can also mount loaded casks back onto the transporters and remove empty casks from the transporters. The Carrier/Cask Handling System receives overpacks from the ATS loaded with canisters that have been cut open and emptied and mounts the overpacks back onto the transporters for disposal. If necessary, the Carrier/Cask Handling System can also mount empty overpacks back onto the transporters and remove loaded overpacks from them. The Carrier/Cask Handling System is located within the Carrier Bay of the Waste Handling Building System. The system consists of cranes, hoists, manipulators, and supporting equipment. The Carrier/Cask Handling System is designed with the tooling and fixtures necessary for handling a variety of casks. The Carrier/Cask Handling System performance and reliability are sufficient to support the shipping and emplacement schedules for the MGR. The Carrier/Cask Handling System interfaces with the Carrier/Cask Transport System, ATS, and CTS as noted above. The Carrier/Cask Handling System interfaces with the Waste Handling Building System for

  2. The roles of vibration analysis and infrared thermography in monitoring air-handling equipment

    NASA Astrophysics Data System (ADS)

    Wurzbach, Richard N.

    2003-04-01

    Industrial and commercial building equipment maintenance has not historically been targeted for implementation of PdM programs. The focus instead has been on manufacturing, aerospace and energy industries where production interruption has significant cost implications. As cost-effectiveness becomes more pervasive in corporate culture, even office space and labor activities housed in large facilities are being scrutinized for cost-cutting measures. When the maintenance costs for these facilities are reviewed, PdM can be considered for improving the reliability of the building temperature regulation, and reduction of maintenance repair costs. An optimized program to direct maintenance resources toward a cost effective and pro-active management of the facility can result in reduced operating budgets, and greater occupant satisfaction. A large majority of the significant rotating machinery in a large building environment are belt-driven air handling units. These machines are often poorly designed or utilized within the facility. As a result, the maintenance staff typically find themselves scrambling to replace belts and bearings, going from one failure to another. Instead of the reactive-mode maintenance, some progressive and critical institutions are adopting predictive and proactive technologies of infrared thermography and vibration analysis. Together, these technologies can be used to identify design and installation problems, that when corrected, significantly reduce maintenance and increase reliability. For critical building use, such as laboratories, research facilities, and other high value non-industrial settings, the cost-benefits of more reliable machinery can contribute significantly to the operational success.

  3. 7 CFR 1436.6 - Eligible storage or handling equipment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... eligible facility loan commodity, such as cleaners, moisture testers, and heat detectors; (4) Electrical... moisture testers, and heat detectors; (vii) Electrical equipment, including labor and materials for..., but are not limited to, the following: An insulated cement slab floor, insulation for walls and...

  4. 7 CFR 1436.6 - Eligible storage or handling equipment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... stored eligible facility loan commodity, such as cleaners, moisture testers, and heat detectors; (4... moisture testers, and heat detectors; (vii) Electrical equipment, including labor and materials for..., but are not limited to, the following: An insulated cement slab floor, insulation for walls and...

  5. 7 CFR 1436.6 - Eligible storage or handling equipment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... eligible facility loan commodity, such as cleaners, moisture testers, and heat detectors; (4) Electrical... moisture testers, and heat detectors; (vii) Electrical equipment, including labor and materials for..., but are not limited to, the following: An insulated cement slab floor, insulation for walls and...

  6. 7 CFR 1436.6 - Eligible storage or handling equipment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... stored eligible facility loan commodity, such as cleaners, moisture testers, and heat detectors; (4... moisture testers, and heat detectors; (vii) Electrical equipment, including labor and materials for..., but are not limited to, the following: An insulated cement slab floor, insulation for walls and...

  7. 7 CFR 1436.6 - Eligible storage or handling equipment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... eligible facility loan commodity, such as cleaners, moisture testers, and heat detectors; (4) Electrical... moisture testers, and heat detectors; (vii) Electrical equipment, including labor and materials for..., but are not limited to, the following: An insulated cement slab floor, insulation for walls and...

  8. 9 CFR 354.242 - Cleaning of equipment and utensils.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... room and equipment and utensils used therein shall be maintained in a clean and sanitary condition. (c... utensils. Equipment and utensils used for preparing or otherwise handling any product shall be kept clean... removed from the plant daily. (b) All equipment and utensils used in the killing and skinning rooms shall...

  9. Metam Sodium and Metam Potassium Fumigant Safe Handling Guide

    EPA Pesticide Factsheets

    Safety training is required for certified pesticide applicators and handlers to handle soil fumigants. Measures to mitigate exposure include personal protective equipment, air monitoring, respiratory protection, and emergency preparedness.

  10. Tools and Equipment Modeling for Automobile Interactive Assembling Operating Simulation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu Dianliang; Zhu Hongmin; Shanghai Key Laboratory of Advance Manufacturing Environment

    Tools and equipment play an important role in the simulation of virtual assembly, especially in the assembly process simulation and plan. Because of variety in function and complexity in structure and manipulation, the simulation of tools and equipments remains to be a challenge for interactive assembly operation. Based on analysis of details and characteristics of interactive operations for automobile assembly, the functional requirement for tools and equipments of automobile assembly is given. Then, a unified modeling method for information expression and function realization of general tools and equipments is represented, and the handling methods of manual, semi-automatic, automatic tools andmore » equipments are discussed. Finally, the application in assembly simulation of rear suspension and front suspension of Roewe 750 automobile is given. The result shows that the modeling and handling methods are applicable in the interactive simulation of various tools and equipments, and can also be used for supporting assembly process planning in virtual environment.« less

  11. How to Handle the Avalanche of Online Documentation.

    ERIC Educational Resources Information Center

    Nolan, Maureen P.

    1981-01-01

    The method of handling the printed documentation associated with online information retrieval, which is described, involves the use of a series of separate but related files: database files, system files, network files, index sheets, and equipment files. (FM)

  12. Supply Support of Air Force 463L Equipment: An Analysis of the 463L equipment Spare Parts Pipeline

    DTIC Science & Technology

    1989-09-01

    service; and 4) the order processing system created inherent delays in the pipeline because of outdated and indirect information systems and technology. Keywords: Materials handling equipment, Theses. (AW)

  13. View from southwest to northeast of warhead handling building. Note ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View from southwest to northeast of warhead handling building. Note earth embankment. The personnel entrance (left) and equipment entrance can clearly be seen in center of photograph. To the right is the emergency exit tunnel constructed of corrugated metal pipe. This building was salvaged and sealed after site inactivation - Stanley R. Mickelsen Safeguard Complex, Warhead Handling Building, Within Exclusion Area, Nekoma, Cavalier County, ND

  14. Satellite services system analysis study. Volume 4: Service equipment concepts

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Payload deployment equipment is discussed, including payload separation, retention structures, the remote manipulator system, tilt tables, the payload installation and deployment aid, the handling and positioning aid, and spin tables. Close proximity retrieval, and on-orbit servicing equipment is discussed. Backup and contingency equipment is also discussed. Delivery and retrieval of high-energy payloads are considered. Earth return equipment, the aft flight deck, optional, and advanced equipment are also discussed.

  15. Lack of genotoxicity in medical oncology nurses handling antineoplastic drugs: effect of work environment and protective equipment.

    PubMed

    Gulten, Tuna; Evke, Elif; Ercan, Ilker; Evrensel, Turkkan; Kurt, Ender; Manavoglu, Osman

    2011-01-01

    In this study we aimed to investigate the genotoxic effects of antineoplastic agents in occupationally exposed oncology nurses. Genotoxic effects mean the disruptive effects in the integrity of DNA and they are associated with cancer development. Biomonitoring of health care workers handling antineoplastic agents is helpful for the evaluation of exposure to cytostatics. The study included an exposed and two control groups. The exposed group (n=9) was comprised of oncology nurses. The first (n=9) and second (n=10) control groups were comprised of subjects who did not come into contact with antineoplastic drugs working respectively in the same department with oncology nurses and in different departments. Genotoxicity evaluation was performed using SCE analysis. After applying culture, harvest and chromosome staining procedures, a total of 25 metaphases were analyzed per person. Kruskal Wallis test was used to perform statistical analysis. A statistically significant difference of sister chromatid exchange frequencies was not observed between the exposed and control groups. Lack of genotoxicity in medical oncology nurses might be due to good working conditions with high standards of technical equipment and improved personal protection.

  16. Effect of training and lifting equipment for preventing back pain in lifting and handling: systematic review

    PubMed Central

    2008-01-01

    Objectives To determine whether advice and training on working techniques and lifting equipment prevent back pain in jobs that involve heavy lifting. Data sources Medline, Embase, CENTRAL, Cochrane Back Group’s specialised register, CINAHL, Nioshtic, CISdoc, Science Citation Index, and PsychLIT were searched up to September-November 2005. Review methods The primary search focused on randomised controlled trials and the secondary search on cohort studies with a concurrent control group. Interventions aimed to modify techniques for lifting and handling heavy objects or patients and including measurements for back pain, consequent disability, or sick leave as the main outcome were considered for the review. Two authors independently assessed eligibility of the studies and methodological quality of those included. For data synthesis, we summarised the results of studies comparing similar interventions. We used odds ratios and effect sizes to combine the results in a meta-analysis. Finally, we compared the conclusions of the primary and secondary analyses. Results Six randomised trials and five cohort studies met the inclusion criteria. Two randomised trials and all cohort studies were labelled as high quality. Eight studies looked at lifting and moving patients, and three studies were conducted among baggage handlers or postal workers. Those in control groups received no intervention or minimal training, physical exercise, or use of back belts. None of the comparisons in randomised trials (17 720 participants) yielded significant differences. In the secondary analysis, none of the cohort studies (772 participants) had significant results, which supports the results of the randomised trials. Conclusions There is no evidence to support use of advice or training in working techniques with or without lifting equipment for preventing back pain or consequent disability. The findings challenge current widespread practice of advising workers on correct lifting technique

  17. 21 CFR 1250.67 - Watering equipment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... permanent signs warning that the water is unfit for drinking. (c) Ice. If bulk ice is used for the cooling..., washing, handling, and delivery to conveyances of such bulk ice, and such equipment shall be used for no...

  18. 21 CFR 1250.67 - Watering equipment.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... permanent signs warning that the water is unfit for drinking. (c) Ice. If bulk ice is used for the cooling..., washing, handling, and delivery to conveyances of such bulk ice, and such equipment shall be used for no...

  19. 21 CFR 1250.67 - Watering equipment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... permanent signs warning that the water is unfit for drinking. (c) Ice. If bulk ice is used for the cooling..., washing, handling, and delivery to conveyances of such bulk ice, and such equipment shall be used for no...

  20. 21 CFR 1250.67 - Watering equipment.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... permanent signs warning that the water is unfit for drinking. (c) Ice. If bulk ice is used for the cooling..., washing, handling, and delivery to conveyances of such bulk ice, and such equipment shall be used for no...

  1. 29 CFR 1926.600 - Equipment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... in the vicinity of power lines or energized transmitters, except where electrical distribution and... an energized line unless and until the person owning such line or the electrical utility authorities... transmitter towers where an electrical charge can be induced in the equipment or materials being handled, the...

  2. 29 CFR 1926.600 - Equipment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... in the vicinity of power lines or energized transmitters, except where electrical distribution and... an energized line unless and until the person owning such line or the electrical utility authorities... transmitter towers where an electrical charge can be induced in the equipment or materials being handled, the...

  3. 29 CFR 1926.600 - Equipment.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... in the vicinity of power lines or energized transmitters, except where electrical distribution and... an energized line unless and until the person owning such line or the electrical utility authorities... transmitter towers where an electrical charge can be induced in the equipment or materials being handled, the...

  4. 29 CFR 1926.600 - Equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... in the vicinity of power lines or energized transmitters, except where electrical distribution and... an energized line unless and until the person owning such line or the electrical utility authorities... transmitter towers where an electrical charge can be induced in the equipment or materials being handled, the...

  5. 76 FR 37118 - Manual Materials Handling (MMH) Workshop

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-24

    ... generating new ideas for manual assist equipment that meets the needs of the business community identified as... Handling (MMH) Workshop. The Workshop is a National Occupational Research Agenda (NORA) activity organized...: [email protected] . Dated: June 15, 2011. Tanya Popovic, Deputy Associate Director for Science, Centers for...

  6. Application of Minicomputers and Microcomputers to Information Handling.

    ERIC Educational Resources Information Center

    Griffiths, Jose-Marie

    This study assesses the application of both minicomputers and microcomputers to information-handling procedures and makes recommendations for automating such procedures, particularly in developing nations. The report is based on a survey of existing uses of small computing equipment in libraries, archives, and information centers which was…

  7. Safe handling practices of cytotoxic drugs: the results of a chapter survey.

    PubMed

    Mahon, S M; Casperson, D S; Yackzan, S; Goodner, S; Hasse, B; Hawkins, J; Parham, J; Rimkus, C; Schlomer, M; Witcher, V

    1994-08-01

    To describe how nurses from a local Oncology Nursing Society (ONS) Chapter Implement Occupational Safety and Health Administration (OSHA) guidelines for handling cytotoxic drugs (CDs) in their individual practices and to identify barriers to implementing these guidelines. Mailed survey. ONS chapter in a large midwestern city. 103 nurses, 83 of whom handle CDs. Mean years in oncology nursing was 7.5. Mailed survey consisting of 48 questions on seven topics, as well as demographic questions. Roles in preparation and administration of CDs, management spills, patient care, and use of protective equipment in patient and family education practices; barriers to use of protective practices. Subjects used some protective equipment when preparing and administering CDs, but the type of equipment and its frequency of use did not specifically meet OSHA Guidelines. Rates of compliance with guidelines were better for management of spills and disposal of equipment. Verbal instructions for patients and families were employed but very few provided written instructions or explanations. Barriers to using protective equipment included a lack of time, problems with availability, and concerns about patient reactions. Barriers must be overcome and better safe-handling practices incorporated into practice to ensure the safety of nurses. More education is needed for family members who come into contact with patients receiving CDs. Future research to document the extent of the problem, including stratification of responses according to the quantity and frequency with which a nurse administers CDs. Better, and perhaps more frequent, staff and family education efforts are needed.

  8. 30 CFR 75.817 - Cable handling and support systems.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Underground High-Voltage Distribution High-Voltage Longwalls § 75.817 Cable handling and support systems. Longwall mining equipment must be... the possibility of miners contacting the cables and to protect the high-voltage cables from damage. ...

  9. 20. MACHINE SHOP, LOOKING SOUTH. SHOP IS EQUIPPED WITH A ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. MACHINE SHOP, LOOKING SOUTH. SHOP IS EQUIPPED WITH A 25-TON SHAW CRANE TO HANDLE PARTS FROM RAIL CARS INTO THE SHOP. MACHINE SHOP HANDLES ALL NECESSARY REPAIR WORK ON THE DOCK MACHINERY. - Pennsylvania Railway Ore Dock, Lake Erie at Whiskey Island, approximately 1.5 miles west of Public Square, Cleveland, Cuyahoga County, OH

  10. Safe handling of antineoplastic drugs.

    PubMed

    Harrison, B R

    1994-07-01

    Managers should be aware of the hazardous properties of antineoplastic drugs and of the procedures and equipment commonly recommended to provide a safe working environment for employees, patients, and visitors. Compliance with the many published guidelines should help ensure passage of the inevitable Occupational Safety and Health Administration (OSHA) or Joint Commission inspection. Acute and chronic toxicities of the antineoplastic drugs, the potential for exposure in the workplace, and the basic guidelines for safe handling of these agents are reviewed.

  11. STS-107 crew members check out equipment at SPACEHAB

    NASA Technical Reports Server (NTRS)

    2000-01-01

    KENNEDY SPACE CENTER, FLA. -- At SPACEHAB, STS-107 crew members check out equipment for their mission. At the far left are Mission Specialists Kalpana Chawla and Ilan Ramon, who is from Israel. At center, handling the equipment, are Mission Specialists David Brown and Michael Anderson. Identified as a research mission, STS-107 is scheduled for launch July 19, 2001

  12. American Nurses Association position statement on elimination of manual patient handling to prevent work-related musculoskeletal disorders.

    PubMed

    In order to establish a safe environment for nurses and patients, the American Nurses Association (ANA) supports actions and policies that result in the elimination of manual patient handling. Patient handling, such as lifting, repositioning, and transferring, has conventionally been performed by nurses. The performance of these tasks exposes nurses to increased risk for work-related musculoskeletal disorders. With the development of assistive equipment, such as lift and transfer devices, the risk of musculoskeletal injury can be significantly reduced. Effective use of assistive equipment and devices for patient handling creates a safe healthcare environment by separating the physical burden from the nurse and ensuring the safety, comfort, and dignity of the patient.

  13. 21 CFR 500.45 - Use of polychlorinated biphenyls (PCB's) in the production, handling, and storage of animal feed.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Food and Drug Administration have revealed that heat exchange fluids for certain pasteurization equipment used in processing animal feed contain PCB's. Although heat exchange fluids in such equipment are... animal feed shall: (i) Have the heat exchange fluid used in existing equipment or machinery for handling...

  14. 21 CFR 500.45 - Use of polychlorinated biphenyls (PCB's) in the production, handling, and storage of animal feed.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Food and Drug Administration have revealed that heat exchange fluids for certain pasteurization equipment used in processing animal feed contain PCB's. Although heat exchange fluids in such equipment are... animal feed shall: (i) Have the heat exchange fluid used in existing equipment or machinery for handling...

  15. Practical Tips for the Safe Handling of Micro-organisms in Schools

    ERIC Educational Resources Information Center

    Holt, G.

    1974-01-01

    Outlines safe laboratory procedures for the handling of micro-organisms including aseptic technique, manipulation of cultures, and treatment of contaminated equipment. Identifies the principal hazard as the microbial aerosol, explains its possible effects, and describes the appropriate precautions. (GS)

  16. Occupational health and safety aspects of animal handling in dairy production.

    PubMed

    Lindahl, Cecilia; Lundqvist, Peter; Hagevoort, G Robert; Lunner Kolstrup, Christina; Douphrate, David I; Pinzke, Stefan; Grandin, Temple

    2013-01-01

    Livestock handling in dairy production is associated with a number of health and safety issues. A large number of fatal and nonfatal injuries still occur when handling livestock. The many animal handling tasks on a dairy farm include moving cattle between different locations, vaccination, administration of medication, hoof care, artificial insemination, ear tagging, milking, and loading onto trucks. There are particular problems with bulls, which continue to cause considerable numbers of injuries and fatalities in dairy production. In order to reduce the number of injuries during animal handling on dairy farms, it is important to understand the key factors in human-animal interactions. These include handler attitudes and behavior, animal behavior, and fear in cows. Care when in close proximity to the animal is the key for safe handling, including knowledge of the flight zone, and use of the right types of tools and suitable restraint equipment. Thus, in order to create safe working conditions during livestock handling, it is important to provide handlers with adequate training and to establish sound safety management procedures on the farm.

  17. Equipment and Supplies For Collecting, Processing, Storing, and Testing Forest Tree Seed

    Treesearch

    F.T. Bonner

    1977-01-01

    This publication is a directory of information on equipment and supplies used in handling and treating tree seed. The use of each device is briefly described. Specifications such as size, capacity, or model number are given. Manufacturers' or suppliers' names are listed, and users of the equipment are identified.

  18. 29 CFR 1918.67 - Notifying the ship's officers before using certain equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Notifying the ship's officers before using certain equipment. 1918.67 Section 1918.67 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Cargo Handling Gear and Equipment Other Than...

  19. Prevalence of and Factors Associated With Minimal Hepatic Encephalopathy in Patients With Cirrhosis of Liver.

    PubMed

    Bale, Abhijith; Pai, C Ganesh; Shetty, Shiran; Balaraju, Girisha; Shetty, Anurag

    2018-06-01

    Minimal hepatic encephalopathy (MHE), though highly prevalent, is a frequently underdiagnosed complication of cirrhosis of the liver. Because lack of time is reported as the major reason for non-testing, identifying patients at high risk of MHE would help in targeting them for screening. We aimed to determine the factors associated with MHE to help identify patient subgroups with a higher risk of MHE for targeted screening. Patients with cirrhosis of liver presenting between April 2015 and November 2016 were included. Those with a Psychometric Hepatic Encephalopathy Score (PHES) of ≤-5 points on psychometric testing were diagnosed to have MHE. Various demographic, clinical and laboratory parameters were included in a univariate and later multiple logistic regression models. Of the 180 (male = 166, 92.2%) patients included 94 (52.2%) had MHE. Though serum albumin, serum total bilirubin, serum aspartate aminotransferase, international normalized ration, Child-Turcotte-Pugh and Model-For-End-Stage-Liver-Disease scores were significant on univariate analysis, only CTP score was found to be significantly associated with MHE ( P  = 0.002) on multivariate analysis. A higher CTP class was associated with a higher risk of the presence of MHE. The Odds ratio for having MHE was higher with CTP classes of B ( P  ≤ 0.001) and C ( P  ≤ 0.001) compared to class A. MHE is a common complication in patients with cirrhosis of liver and higher CTP scores independently predict the presence of MHE. Patients with CTP class B and C have a higher risk of suffering from MHE than CTP class A. Screening of patients in CTP class B and C is likely to increase the MHE detection rates while saving time, although select CTP class A patients may also need screening in view of public safety or poor quality of life.

  20. Navigation skill impairment: Another dimension of the driving difficulties in minimal hepatic encephalopathy.

    PubMed

    Bajaj, Jasmohan S; Hafeezullah, Muhammad; Hoffmann, Raymond G; Varma, Rajiv R; Franco, Jose; Binion, David G; Hammeke, Thomas A; Saeian, Kia

    2008-02-01

    Patients with minimal hepatic encephalopathy (MHE) have attention, response inhibition, and working memory difficulties that are associated with driving impairment and high motor vehicle accident risk. Navigation is a complex system needed for safe driving that requires functioning working memory and other domains adversely affected by MHE. The aim of this study was to determine the effect of MHE on navigation skills and correlate them with psychometric impairment. Forty-nine nonalcoholic patients with cirrhosis (34 MHE+, 15 MHE-; divided on the basis of a battery of block design, digit symbol, and number connection test A) and 48 age/education-matched controls were included. All patients underwent the psychometric battery and inhibitory control test (ICT) (a test of response inhibition) and driving simulation. Driving simulation consisted of 4 parts: (1) training; (2) driving (outcome being accidents); (3) divided attention (outcome being missed tasks); and (4) navigation, driving along a marked path on a map in a "virtual city" (outcome being illegal turns). Illegal turns were significantly higher in MHE+ (median 1; P = 0.007) compared with MHE-/controls (median 0). Patients who were MHE+ missed more divided attention tasks compared with others (median MHE+ 1, MHE-/controls 0; P = 0.001). Similarly, accidents were higher in patients who were MHE+ (median 2.5; P = 0.004) compared with MHE- (median 1) or controls (median 2). Accidents and illegal turns were significantly correlated (P = 0.001, r = 0.51). ICT impairment was the test most correlated with illegal turns (r = 0.6) and accidents (r = 0.44), although impairment on the other tests were also correlated with illegal turns. Patients positive for MHE have impaired navigation skills on a driving simulator, which is correlated with impairment in response inhibition (ICT) and attention. This navigation difficulty may pose additional driving problems, compounding the pre-existing deleterious effect of attention

  1. [Nursing workers' perceptions regarding the handling of hazardous chemical waste].

    PubMed

    Costa, Taiza Florêncio; Felli, Vanda Elisa Andres; Baptista, Patrícia Campos Pavan

    2012-12-01

    The objectives of this study were to identify the perceptions of nursing workers regarding the handling of hazardous chemical waste at the University of São Paulo University Hospital (HU-USP), and develop a proposal to improve safety measures. This study used a qualitative approach and a convenience sample consisting of eighteen nursing workers. Data collection was performed through focal groups. Thematic analysis revealed four categories that gave evidence of training deficiencies in terms of the stages of handling waste. Difficulties that emerged included a lack of knowledge regarding exposure and its impact, the utilization of personal protective equipment versus collective protection, and suggestions regarding measures to be taken by the institution and workers for the safe handling of hazardous chemical waste. The present data allowed for recommending proposals regarding the safe management of hazardous chemical waste by the nursing staff.

  2. Systems for harvesting and handling cotton plant residue

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Coates, W.

    1993-12-31

    In the warmer regions of the United States, cotton plant residue must be buried to prevent it from serving as an overwintering site for insect pests such as the pink bollworm. Most of the field operations used to bury the residue are high energy consumers and tend to degrade soil structure, thereby increasing the potential for erosion. The residue is of little value as a soil amendment and consequently is considered a negative value biomass. A commercial system to harvest cotton plant residue would be of both economic and environmental benefit to cotton producers. Research has been underway at themore » University of Arizona since the spring of 1991 to develop a commercially viable system for harvesting cotton plant residue. Equipment durability, degree of densification, energy required, cleanliness of the harvested material, and ease of product handling and transport are some of the performance variables which have been measured. Two systems have proven superior. In both, the plants are pulled from the ground using an implement developed specifically for the purpose. In one system, the stalks are baled using a large round baler, while in the other the stalks are chopped with a forage harvester, and then made into packages using a cotton module maker. Field capacities, energy requirements, package density and durability, and ease of handling with commercially available equipment have been measured for both systems. Selection of an optimum system for a specific operation depends upon end use of the product, and upon equipment availability.« less

  3. Individual Information-Centered Approach for Handling Physical Activity Missing Data

    ERIC Educational Resources Information Center

    Kang, Minsoo; Rowe, David A.; Barreira, Tiago V.; Robinson, Terrance S.; Mahar, Matthew T.

    2009-01-01

    The purpose of this study was to validate individual information (II)-centered methods for handling missing data, using data samples of 118 middle-aged adults and 91 older adults equipped with Yamax SW-200 pedometers and Actigraph accelerometers for 7 days. We used a semisimulation approach to create six data sets: three physical activity outcome…

  4. Airborne bacteria and fungi associated with waste-handling work.

    PubMed

    Park, Donguk; Ryu, Seunghun; Kim, Shinbum; Byun, Hyaejeong; Yoon, Chungsik; Lee, Kyeongmin

    2013-01-01

    Municipal workers handling household waste are potentially exposed to a variety of toxic and pathogenic substances, in particular airborne bacteria, gram-negative bacteria (GNB), and fungi. However, relatively little is known about the conditions under which exposure is facilitated. This study assessed levels of airborne bacteria, GNB, and fungi, and examined these in relation to the type of waste-handling activity (collection, transfer, transport, and sorting at the waste preprocessing plant), as well as a variety of other environmental and occupational factors. Airborne microorganisms were sampled using an Andersen single-stage sampler equipped with agar plates containing the appropriate nutritional medium and then cultured to determine airborne levels. Samples were taken during collection, transfer, transport, and sorting of household waste. Multiple regression analysis was used to identify environmental and occupational factors that significantly affect airborne microorganism levels during waste-handling activities. The "type of waste-handling activity" was the only factor that significantly affected airborne levels of bacteria and GNB, accounting for 38% (P = 0.029) and 50% (P = 0.0002) of the variation observed in bacteria and GNB levels, respectively. In terms of fungi, the type of waste-handling activity (R2 = 0.76) and whether collection had also occurred on the day prior to sampling (P < 0.0001, R2 = 0.78) explained most of the observed variation. Given that the type of waste-handling activity was significantly correlated with levels of bacteria, GNB, and fungi, we suggest that various engineering, administrative, and regulatory measures should be considered to reduce the occupational exposure to airborne microorganisms in the waste-handling industry.

  5. Eye-in-Hand Manipulation for Remote Handling: Experimental Setup

    NASA Astrophysics Data System (ADS)

    Niu, Longchuan; Suominen, Olli; Aref, Mohammad M.; Mattila, Jouni; Ruiz, Emilio; Esque, Salvador

    2018-03-01

    A prototype for eye-in-hand manipulation in the context of remote handling in the International Thermonuclear Experimental Reactor (ITER)1 is presented in this paper. The setup consists of an industrial robot manipulator with a modified open control architecture and equipped with a pair of stereoscopic cameras, a force/torque sensor, and pneumatic tools. It is controlled through a haptic device in a mock-up environment. The industrial robot controller has been replaced by a single industrial PC running Xenomai that has a real-time connection to both the robot controller and another Linux PC running as the controller for the haptic device. The new remote handling control environment enables further development of advanced control schemes for autonomous and semi-autonomous manipulation tasks. This setup benefits from a stereovision system for accurate tracking of the target objects with irregular shapes. The overall environmental setup successfully demonstrates the required robustness and precision that remote handling tasks need.

  6. Fiber-handling robot and optical connection mechanisms for automatic cross-connection of multiple optical connectors

    NASA Astrophysics Data System (ADS)

    Mizukami, Masato; Makihara, Mitsuhiro

    2013-07-01

    Conventionally, in intelligent buildings in a metropolitan area network and in small-scale facilities in the optical access network, optical connectors are joined manually using an optical connection board and a patch panel. In this manual connection approach, mistakes occur due to discrepancies between the actual physical settings of the connections and their management because these processes are independent. Moreover, manual cross-connection is time-consuming and expensive because maintenance personnel must be dispatched to remote places to correct mistakes. We have developed a fiber-handling robot and optical connection mechanisms for automatic cross-connection of multiple optical connectors, which are the key elements of automatic optical fiber cross-connect equipment. We evaluate the performance of the equipment, such as its optical characteristics and environmental specifications. We also devise new optical connection mechanisms that enable the automated optical fiber cross-connect module to handle and connect angled physical contact (APC) optical connector plugs. We evaluate the performance of the equipment, such as its optical characteristics. The evaluation results confirm that the automated optical fiber cross-connect equipment can connect APC connectors with low loss and high return loss, indicating that the automated optical fiber cross-connect equipment is suitable for practical use in intelligent buildings and optical access networks.

  7. Minimal hepatic encephalopathy in children with chronic liver disease: Prevalence, pathogenesis and magnetic resonance-based diagnosis.

    PubMed

    Srivastava, Anshu; Chaturvedi, Saurabh; Gupta, Rakesh Kumar; Malik, Rohan; Mathias, Amrita; Jagannathan, Naranamangalam R; Jain, Sunil; Pandey, Chandra Mani; Yachha, Surender Kumar; Rathore, Ram Kishor Singh

    2017-03-01

    Data on minimal hepatic encephalopathy (MHE) in children is scarce. We aimed to study MHE in children with chronic liver disease (CLD) and to validate non-invasive objective tests which can assist in its diagnosis. We evaluated 67 children with CLD (38 boys; age 13 [7-18] years) and 37 healthy children to determine the prevalence of MHE. We also assessed the correlation of MHE with changes in brain metabolites by magnetic resonance spectroscopy ( 1 HMRS), diffusion tensor imaging (DTI) derived metrics, blood ammonia and inflammatory cytokines (interleukin-6 [IL6], tumor necrosis factor alpha [TNF-α]). In addition, the accuracy of MR-based investigations for diagnosis of MHE in comparison to neuropsychological tests was analysed. Thirty-four (50.7%) children with CLD had MHE on neuropsychological tests. MHE patients had higher BA (30.5 [6-74] vs. 14 [6-66]μmol/L; p=0.02), IL-6 (8.3 [4.7-28.7] vs. 7.6 [4.7-20.7]pg/ml; p=0.4) and TNF-α (17.8 [7.8-65.5] vs. 12.8 [7.5-35]pg/ml; p=0.06) than No-MHE. 1 HMRS showed higher glutamine (2.6 [2.1-3.3] vs. 2.4 [2.0-3.1]; p=0.02), and lower choline (0.20 [0.14-0.25] vs. 0.22 [0.17-0.28]; p=0.1) and myo-inositol (0.25 [0.14-0.41] vs. 0.29 [0.21-0.66]; p=0.2) in MHE patients than those without MHE. Mean diffusivity (MD) on DTI was significantly higher in 6/11 brain areas in patients with MHE vs. no MHE. Brain glutamine had a significant positive correlation with blood ammonia, IL-6, TNF-α and MD of various brain regions. Neuropsychological tests showed a negative correlation with blood ammonia, IL6, TNF-α, glutamine and MD. Frontal white matter MD had a sensitivity and specificity of 73.5% and 100% for diagnosing MHE. In children with CLD, 50% have MHE. There is a significant positive correlation between markers of hyperammonemia, inflammation and brain edema and these correlate negatively with neuropsychological tests. MD on DTI is a reliable tool for diagnosing MHE. Fifty percent of children with chronic liver disease

  8. Queuing theory models used for port equipment sizing

    NASA Astrophysics Data System (ADS)

    Dragu, V.; Dinu, O.; Ruscă, A.; Burciu, Ş.; Roman, E. A.

    2017-08-01

    The significant growth of volumes and distances on road transportation led to the necessity of finding solutions to increase water transportation market share together with the handling and transfer technologies within its terminals. It is widely known that the biggest times are consumed within the transport terminals (loading/unloading/transfer) and so the necessity of constantly developing handling techniques and technologies in concordance with the goods flows size so that the total waiting time of ships within ports is reduced. Port development should be achieved by harmonizing the contradictory interests of port administration and users. Port administrators aim profit increase opposite to users that want savings by increasing consumers’ surplus. The difficulty consists in the fact that the transport demand - supply equilibrium must be realised at costs and goods quantities transiting the port in order to satisfy the interests of both parties involved. This paper presents a port equipment sizing model by using queueing theory so that the sum of costs for ships waiting operations and equipment usage would be minimum. Ship operation within the port is assimilated to a mass service waiting system in which parameters are later used to determine the main costs for ships and port equipment.

  9. 49 CFR 232.609 - Handling of defective equipment with ECP brake systems.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... and appropriate operating and inspection personnel; and (3) An electronic or written record of the... operating freight cars equipped with ECP brake systems shall adopt and comply with specific procedures... this subpart. These procedures shall be made available to FRA upon request. (2) Each railroad operating...

  10. TA-60-1 Heavy Equipment Shop Areas SWPPP Rev 2 Jan 2017-Final

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burgin, Jillian Elizabeth

    The primary activities and equipment areas at the facility that are potential stormwater pollution sources include; The storage of vehicles and heavy equipment awaiting repair; or repaired vehicles waiting to be picked up; The storage and handling of oils, anti-freeze, solvents, degreasers, batteries and other chemicals for the maintenance of vehicles and heavy equipment; and Equipment cleaning operations including exterior vehicle wash-down. Steam cleaning is only done on the steam cleaning pad area located at the north east end of Building 60-0001.

  11. Principles of commercially available pretreatment and feeding equipment for baled biomass

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Koch, T.; Hummelshoej, R.M.

    1993-12-31

    During the last 15 years, there has been a growing interest in utilizing waste biomass for energy production in Denmark. Since 1990, it has been unlawful to burn surplus straw on open land. Before the year 2000, it is intended to utilize most of the 2--3 million tons of surplus straw as an energy resource. The type of plants that were built in the beginning were combustion plants for district heating. The feeding equipment for these plants has been developed to an acceptable standard. Later, combustion plants for combined heat and power production based on a steam turbine were introduced.more » This type of plant demands a much greater continuity in the fuel flow, and the consequences of minor discontinuities are to be dropped from the grid. Gasification and pyrolysis demands a high sealing ability of the feeding equipment, because of the explosive and poisonous gas in the plant and a need for a very high continuity in the fuel feed. The first plants were built with the equipment and experiences from the farming industries, which have a long tradition in working with biomass-handling. The experiences gained with this type of equipment were not very promising, and in the early eighties, a more industrial type of biomass-handling equipment was developed. This paper presents the principles of the heavy-duty biomass pretreatment and feeding equipment that was commercially available in Denmark in May, 1993.« less

  12. Proposed space shuttle cargo handling criteria at the operational site (preliminary)

    NASA Technical Reports Server (NTRS)

    Beck, P. E.

    1972-01-01

    The criteria for cargo handling at the operational site of space shuttles are presented, based on assumed program requirements. The concepts for the following functions are described: maintenance and checkout facility, transfer to launch pad, and launch pad. The requirements for the ground equipment are given along with the general sequences for cargo loading.

  13. Port of Los Angeles: Off-Road Heavy Duty Equipment and Infrastructure Enhancements

    EPA Pesticide Factsheets

    Description of a project at the Port of Los Angeles to replace a diesel crane with an electric crane. Additionally includes information on shore power installation, and cargo handling equipment upgrades.

  14. Real-time moving horizon estimation for a vibrating active cantilever

    NASA Astrophysics Data System (ADS)

    Abdollahpouri, Mohammad; Takács, Gergely; Rohaľ-Ilkiv, Boris

    2017-03-01

    Vibrating structures may be subject to changes throughout their operating lifetime due to a range of environmental and technical factors. These variations can be considered as parameter changes in the dynamic model of the structure, while their online estimates can be utilized in adaptive control strategies, or in structural health monitoring. This paper implements the moving horizon estimation (MHE) algorithm on a low-cost embedded computing device that is jointly observing the dynamic states and parameter variations of an active cantilever beam in real time. The practical behavior of this algorithm has been investigated in various experimental scenarios. It has been found, that for the given field of application, moving horizon estimation converges faster than the extended Kalman filter; moreover, it handles atypical measurement noise, sensor errors or other extreme changes, reliably. Despite its improved performance, the experiments demonstrate that the disadvantage of solving the nonlinear optimization problem in MHE is that it naturally leads to an increase in computational effort.

  15. The detection of blood on dental surgery surfaces and equipment following dental hygiene treatment.

    PubMed

    McColl, E; Bagg, J; Winning, S

    1994-01-22

    The Kastle-Meyer technique, a forensic test for blood, has been employed to assess the frequency and potential routes of contamination by blood between patients, staff and equipment during routine dental hygiene treatment. Fifty treatment sessions were studied and units were cleaned between patients according to the current hospital protocol. The surfaces most frequently contaminated after treatment were the 3-in-1 syringe buttons (40%), protective bibs (22%), tap handles (20%), light handles (18%) and operating cart handles (16%). Following cleaning of the units, the surfaces remaining contaminated were the 3-in-1 syringes (10%), tap handles (4%) and cart handles (2%). Modifications to the cross-infection control protocol have been made to eliminate these sources of contamination.

  16. Touch Temperature Coating for Off-the-Shelf Electrical Equipment Used on Spacecraft

    NASA Technical Reports Server (NTRS)

    Ungar, Eugene K.; Brady, Timothy K.

    2010-01-01

    Off-the-shelf electrical equipment is frequently used in space-based applications to control costs. However, the reduced heat transfer in the spacecraft microgravity environment causes the equipment to operate at significantly higher temperatures than it would in terrestrial applications. This creates touch temperature issues where items particularly metallic ones become too hot for the crew to handle safely. A touch temperature coating layup has been developed that can be added to spacebased electrically powered hardware. The coating allows the crew to safely handle the hardware, but only slightly impedes the heat transfer from the component during normal operation. In the present work, the coating generic requirements are developed and a layup is described that meets these specifications. Analytical and experimental results are presented that demonstrate the ability of the coating layup to increase the allowable limits of touch temperature while only marginally degrading heat transfer to the environment. This allows the spacecraft crew to handle objects that, if not coated, would be hot enough to cause pain or skin damage.

  17. 21 CFR 600.11 - Physical establishment, equipment, animals, and care.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Physical establishment, equipment, animals, and... designed and constructed to permit thorough cleaning and, where possible, inspection for cleanliness. All... each culture is designed to withstand handling without breaking. (3) Work with spore-forming...

  18. Adverse risk: a 'dynamic interaction model of patient moving and handling'.

    PubMed

    Griffiths, Howard

    2012-09-01

    The aim of the present study was to examine patient adverse events associated with sub-optimal patient moving and handling. Few studies have examined the patient's perspective on adverse risk during manual handling episodes. A narrative review was undertaken to develop the 'Dynamic Interaction Model of Patient Moving and Handling' in an orthopaedic rehabilitation setting, using peer-reviewed publications published in English between 1992 and 2010. Five predominant themes emerged from the narrative review: 'patient's need to know about analgesics prior to movement/ambulation'; 'comfort care'; 'mastery of and acceptance of mobility aids/equipment'; 'psychological adjustment to fear of falling'; and 'the need for movement to prevent tissue pressure damage'. Prevalence of discomfort, pain, falls, pressure sores together with a specific Direct Instrument Nursing Observation (DINO) tool enable back care advisers to measure quality of patient manual handling. Evaluation of patients' use of mobility aids together with fear of falling may be important in determining patients' recovery trajectory. Clinical governance places a responsibility on nurse managers to consider quality of care for their service users. 'Dynamic Interaction Model of Nurse-Patient Moving and Handling' provides back care advisers, clinical risk managers and occupational health managers with an alternative perspective to clinical risk and occupational risk. © 2011 Blackwell Publishing Ltd.

  19. Design and simulation of integration system between automated material handling system and manufacturing layout in the automotive assembly line

    NASA Astrophysics Data System (ADS)

    Seha, S.; Zamberi, J.; Fairu, A. J.

    2017-10-01

    Material handling system (MHS) is an important part for the productivity plant and has recognized as an integral part of today’s manufacturing system. Currently, MHS has growth tremendously with its technology and equipment type. Based on the case study observation, the issue involving material handling system contribute to the reduction of production efficiency. This paper aims to propose a new design of integration between material handling and manufacturing layout by investigating the influences of layout and material handling system. A method approach tool using Delmia Quest software is introduced and the simulation result is used to assess the influences of the integration between material handling system and manufacturing layout in the performance of automotive assembly line. The result show, the production of assembly line output increases more than 31% from the current system. The source throughput rate average value went up to 252 units per working hour in model 3 and show the effectiveness of the pick-to-light system as efficient storage equipment. Thus, overall result shows, the application of AGV and the pick-to-light system gave a large significant effect in the automotive assembly line. Moreover, the change of layout also shows a large significant improvement to the performance.

  20. 109. EAST WALL OF MECHANICAL EQUIPMENT ROOM (201), LSB (BLDG. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    109. EAST WALL OF MECHANICAL EQUIPMENT ROOM (201), LSB (BLDG. 751): TEMPERATURE, FLOW RATE, AND HUMIDITY MONITORING CONTROLS FOR SYSTEM 1 AND SYSTEM 2 AIR HANDLING - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 East, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  1. 92. EAST WALL OF MECHANICAL EQUIPMENT ROOM (101), LSB (BLDG. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    92. EAST WALL OF MECHANICAL EQUIPMENT ROOM (101), LSB (BLDG. 770). TEMPERATURE, FLOW RATE, AND HUMIDITY MONITORING CONTROLS FOR SYSTEM 1 AND SYSTEM 2 AIR HANDLING. - Vandenberg Air Force Base, Space Launch Complex 3, Launch Pad 3 West, Napa & Alden Roads, Lompoc, Santa Barbara County, CA

  2. Do Technical Aids for Patient Handling Prevent Musculoskeletal Complaints in Health Care Workers?-A Systematic Review of Intervention Studies.

    PubMed

    Hegewald, Janice; Berge, Wera; Heinrich, Philipp; Staudte, Ronny; Freiberg, Alice; Scharfe, Julia; Girbig, Maria; Nienhaus, Albert; Seidler, Andreas

    2018-03-09

    The physical load ensuing from the repositioning and moving of patients puts health care workers at risk of musculoskeletal complaints. Technical equipment developed to aid with patient handling should reduce physical strain and workload; however, the efficacy of these aids in preventing musculoskeletal disorders and complaints is still unclear. A systematic review of controlled intervention studies was conducted to examine if the risk of musculoskeletal complaints and disorders is reduced by technical patient handling equipment. MEDLINE ® /PubMed ® , EMBASE ® , Allied and Complementary Medicine Database (AMED), and Cumulative Index of Nursing and Allied Health Literature (CINAHL ® ) were searched using terms for nursing, caregiving, technical aids, musculoskeletal injuries, and complaints. Randomized controlled trials and controlled before-after studies of interventions including technical patient handling equipment were included. The titles and abstracts of 9554 publications and 97 full-texts were screened by two reviewers. The qualitative synthesis included one randomized controlled trial (RCT) and ten controlled before-after studies. A meta-analysis of four studies resulted in a pooled risk ratio for musculoskeletal injury claims (post-intervention) of 0.78 (95% confidence interval 0.68-0.90). Overall, the methodological quality of the studies was poor and the results often based on administrative injury claim data, introducing potential selection bias. Interventions with technical patient handling aids appear to prevent musculoskeletal complaints, but the certainty of the evidence according to GRADE approach ranged from low to very low.

  3. Assessment of minimal hepatic encephalopathy (with emphasis on computerized psychometric tests).

    PubMed

    Kappus, Matthew R; Bajaj, Jasmohan S

    2012-02-01

    Minimal hepatic encephalopathy (MHE) is associated with a high risk of development of overt hepatic encephalopathy, impaired quality of life, and driving accidents. The detection of MHE requires specialized testing because it cannot, by definition, be diagnosed on standard clinical examination. Psychometric and neurophysiologic techniques are often used to test for MHE. Paper-pencil psychometric batteries and computerized tests have proved useful in diagnosing MHE and predicting its outcomes. Neurophysiologic tests also provide useful information. The diagnosis of MHE is an important issue for clinicians and patients alike. Testing strategies depend on the normative data available, patient comfort, and local expertise. Copyright © 2012 Elsevier Inc. All rights reserved.

  4. Thermodynamic processes associated with frostbite in the handling of liquid nitrogen

    NASA Astrophysics Data System (ADS)

    Johnson, W. L.; Cook, C. R.

    2014-01-01

    It is often taught that exposure to liquid nitrogen will cause frostbite or more severe damage to exposed skin tissue. However, it is also demonstrated that a full hand can be briefly immersed in liquid nitrogen without damage. To better understand and possibly visualize the effects of human tissue exposure to liquid nitrogen, a series of tests were conducted using simulated hands and arms composed of molded gelatin forms. The simulated hands and arms were immersed, sprayed, or splashed with liquid nitrogen both with and without state of the art personal protective equipment. Thermocouples were located within the test articles to allow for thermal mapping during the freezing process. The study is aimed to help understand frostbite hazards and the time constants involved with the handling of liquid nitrogen to improve future safety protocols for the safe handling of cryogenic fluids. Results of the testing also show the limits to handling liquid nitrogen while using various means of protection.

  5. Moving Horizon Estimation on a Chip

    DTIC Science & Technology

    2014-06-26

    description, e.g. VHDL or Verilog, for FPGA implementation . Especially for those whose main expertise is in control system design, writing algorithms in C...ditional Kalman Filter(KF) where recursive solution is available. We devel- oped various MHE designs and implemented them on the Xilinx Zynq ZC702 FPGA...practical deployment of the MHE technology. 2.2 Implementation of MHE on FPGA The next paper demonstrated the feasibility of implementing MHE algo

  6. Sleep disturbances in patients of liver cirrhosis with minimal hepatic encephalopathy before and after lactulose therapy.

    PubMed

    Singh, Jatinderpal; Sharma, Barjesh Chander; Puri, Vinod; Sachdeva, Sanjeev; Srivastava, Siddharth

    2017-04-01

    Sleep disturbances are common in patients of cirrhosis with minimal hepatic encephalopathy (MHE) and affect health related quality of life (HRQOL). No study has evaluated effect of lactulose on sleep disturbances and correlation with HRQOL in patients with MHE. We assessed sleep disturbances in cirrhosis with MHE and effect of lactulose on sleep disturbances and HRQOL. One hundred patients of cirrhosis [MHE; (n = 50, age 45.3 ± 11.2 years, 45 males) no-MHE (n = 50, age 46.3 ± 10.4 years, 44 males)] were included. MHE was diagnosed with psychometric hepatic encephalopathy score (PHES) ≤ -5. All patients underwent laboratory parameters including arterial ammonia and critical flicker frequency (CFF) Sleep disturbances were measured with Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS) and polysomnography. HRQOL was measured with SF-36(v2) questionnaire. Patients with MHE were given lactulose therapy for 3 months and all the parameters were repeated. Poor quality of sleep and excessive day time sleepiness were more common in patients with MHE, compared to without MHE. With lactulose therapy there was improvement in MHE in 21 patients and arterial ammonia levels (93.74 ± 14.8 vs. 71.44 ± 18.8 μmol/L: p < 0.001), CFF (34.83 ± 3.54 vs. 39.44 ± 4.95 Hz: p < 0.001), PHES (-7.64 ± 2.1 vs. -5.58 ± 2.09: p < 0.001), PSQI (8.6 ± 3.3 vs. 5.2 ± 1.5: p < 0.001), ESS (12.52 ± 3.01 vs. 9.24 ± 2.27: p < 0.001) and HRQOL (p = 0.01). Excessive day time sleepiness and impaired sleep quality are common in patients with MHE and correlate with neuropsychiatric impairment. Improvement in MHE with lactulose also leads to improvement in sleep disturbances and HRQOL.

  7. Spectral electroencephalogram in liver cirrhosis with minimal hepatic encephalopathy before and after lactulose therapy.

    PubMed

    Singh, Jatinderpal; Sharma, Barjesh Chander; Maharshi, Sudhir; Puri, Vinod; Srivastava, Siddharth

    2016-06-01

    Minimal hepatic encephalopathy (MHE) represents the mildest form of hepatic encephalopathy. Spectral electroencephalogram (sEEG) analysis improves the recognition of MHE by decreasing inter-operator variability and providing quantitative parameters of brain dysfunction. We compared sEEG in patients with cirrhosis with and without MHE and the effects of lactulose on sEEG in patients with MHE. One hundred patients with cirrhosis (50 with and 50 without MHE) were enrolled. Diagnosis of MHE was based on psychometric hepatic encephalopathy score (PHES) of ≤ -5. Critical flicker frequency, model of end-stage liver disease score, and sEEG were performed at baseline in all patients. The spectral variables considered were the mean dominant frequency (MDF) and relative power in beta, alpha, theta, and delta bands. Patients with MHE were given 3 months of lactulose, and all parameters were repeated. Spectral electroencephalogram analysis showed lower MDF (7.8 ± 1.7 vs 8.7 ± 1.3 Hz, P < 0.05) and higher theta relative power (34.29 ± 4.8 vs 24 ± 6.7%, P = 001) while lower alpha relative power (28.6 ± 4.0 vs 33.5 ± 5.3%, P = .001) in patients with MHE than in patients without MHE. With theta relative power, sensitivity 96%, specificity 84%, and accuracy of 90% were obtained for diagnosis of MHE. After lactulose treatment, MHE improved in 21 patients, and significant changes were seen in MDF (7.8 ± 0.5 vs 8.5 ± 0.6), theta (34.2 ± 4.8 vs 23.3 ± 4.1%), alpha (28.6 ± 4.0 vs 35.5 ± 4.5%), and delta relative power (13.7 ± 3.5 vs 17.0 ± 3.3%) after treatment (P ≤ 0.05). Spectral EEG is a useful objective and quantitative tool for diagnosis and to assess the response to treatment in patients with cirrhosis with MHE. © 2015 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.

  8. AORN ergonomic tool 7: pushing, pulling, and moving equipment on wheels.

    PubMed

    Waters, Thomas; Lloyd, John D; Hernandez, Edward; Nelson, Audrey

    2011-09-01

    Pushing and pulling equipment in and around the OR can place high shear force demands on perioperative team members' shoulder and back muscles and joints. These high forces may lead to work-related musculoskeletal disorders. AORN Ergonomic Tool 7: Pushing, Pulling, and Moving Equipment on Wheels can help perioperative team members assess the risk of pushing and pulling tasks in the perioperative setting. The tool provides evidence-based suggestions about when assistive devices should be used for these tasks and is based on current ergonomic safety concepts, scientific evidence, and knowledge of effective technology and procedures, including equipment and devices for safe patient handling. Published by Elsevier Inc.

  9. The influence of residents' behaviour on waste electrical and electronic equipment collection effectiveness.

    PubMed

    Nowakowski, Piotr

    2016-11-01

    Government agencies have implemented regulations to reduce the volume of waste electrical and electronic equipment to protect the environment and encourage recycling. The effectiveness of systems through which waste electrical and electronic equipment is collected and recycled depends on (a) the development and operation of new programmes to process this material and (b) on information dissemination programmes aimed at manufacturers, retail sellers, and the consuming public. This study analyses these two elements. The main focus is to better understand household residents' behaviour in regards to the proper methods of handling waste electrical and electronic equipment and possible storage of the obsolete equipment that brings disturbances with collection of the waste equipment. The study explores these issues depending on size of municipality and the household residents' knowledge about legal methods of post-consumer management of waste electrical and electronic equipment in Poland, where the collection rate of that type of waste is about 40% of the total mass of waste electrical and electronic equipment appearing in the market.The research was informed by various sources of information, including non-government organisations, Inspectorate of Environmental Protection and Central Statistics Office in Poland, questionnaires, and interviews with the household residents. The questionnaires were distributed to daytime and vocational students from different universities and the customers of an electronic equipment superstore. The results show that a resident's behaviour in regards to the handling of obsolete waste electrical and electronic equipment can significantly reduce the collection rate, especially when the waste is discarded improperly - mixed with municipal waste or sold in scrapyards. It is possible to identify points that are necessary to be improved to achieve a higher collection rate. © The Author(s) 2016.

  10. Do Technical Aids for Patient Handling Prevent Musculoskeletal Complaints in Health Care Workers?—A Systematic Review of Intervention Studies

    PubMed Central

    Hegewald, Janice; Berge, Wera; Heinrich, Philipp; Staudte, Ronny; Freiberg, Alice; Scharfe, Julia; Girbig, Maria; Nienhaus, Albert; Seidler, Andreas

    2018-01-01

    The physical load ensuing from the repositioning and moving of patients puts health care workers at risk of musculoskeletal complaints. Technical equipment developed to aid with patient handling should reduce physical strain and workload; however, the efficacy of these aids in preventing musculoskeletal disorders and complaints is still unclear. A systematic review of controlled intervention studies was conducted to examine if the risk of musculoskeletal complaints and disorders is reduced by technical patient handling equipment. MEDLINE®/PubMed®, EMBASE®, Allied and Complementary Medicine Database (AMED), and Cumulative Index of Nursing and Allied Health Literature (CINAHL®) were searched using terms for nursing, caregiving, technical aids, musculoskeletal injuries, and complaints. Randomized controlled trials and controlled before-after studies of interventions including technical patient handling equipment were included. The titles and abstracts of 9554 publications and 97 full-texts were screened by two reviewers. The qualitative synthesis included one randomized controlled trial (RCT) and ten controlled before-after studies. A meta-analysis of four studies resulted in a pooled risk ratio for musculoskeletal injury claims (post-intervention) of 0.78 (95% confidence interval 0.68–0.90). Overall, the methodological quality of the studies was poor and the results often based on administrative injury claim data, introducing potential selection bias. Interventions with technical patient handling aids appear to prevent musculoskeletal complaints, but the certainty of the evidence according to GRADE approach ranged from low to very low. PMID:29522440

  11. The Heroes' Problems: Exploring the Potentials of Google Glass for Biohazard Handling Professionals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chang, Jack Shen-Kuen; Henry, Michael J.; Burtner, Edwin R.

    2015-06-23

    In “white powder incidents” or other suspicious and risky situations relating to deadly diseases or chemicals (e.g., Ebola investigation), those who handle the potentially hazardous materials are the heroes who spearhead the first responder’s operations. Although well trained, these heroes need to manage complex problems and make life-or-death decisions while handling the unknown and dangerous. We are motivated to explore how Google Glass can facilitate those heroes’ missions. To this end, we conducted contextual inquiry on six biohazard-handling, Personal Protective Equipment (PPE)-wearing professionals. With an inductive thematic analysis, we summarized the heroes’ workflow and four groups of “Heroes’ Problems”. Amore » unique “A3 Model” (Awareness, Analysis, Action) was generated to encapsulate our qualitative findings and proposed Glass features. The findings serve as the groundwork for our future development.« less

  12. Learning and Memory Impairments in Patients with Minimal Hepatic Encephalopathy are Associated with Structural and Functional Connectivity Alterations in Hippocampus.

    PubMed

    García-García, Raquel; Cruz-Gómez, Álvaro Javier; Urios, Amparo; Mangas-Losada, Alba; Forn, Cristina; Escudero-García, Desamparados; Kosenko, Elena; Torregrosa, Isidro; Tosca, Joan; Giner-Durán, Remedios; Serra, Miguel Angel; Avila, César; Belloch, Vicente; Felipo, Vicente; Montoliu, Carmina

    2018-06-25

    Patients with minimal hepatic encephalopathy (MHE) show mild cognitive impairment associated with alterations in attentional and executive networks. There are no studies evaluating the relationship between memory in MHE and structural and functional connectivity (FC) changes in the hippocampal system. This study aimed to evaluate verbal learning and long-term memory in cirrhotic patients with (C-MHE) and without MHE (C-NMHE) and healthy controls. We assessed the relationship between alterations in memory and the structural integrity and FC of the hippocampal system. C-MHE patients showed impairments in learning, long-term memory, and recognition, compared to C-NMHE patients and controls. Cirrhotic patients showed reduced fimbria volume compared to controls. Larger volumes in hippocampus subfields were related to better memory performance in C-NMHE patients and controls. C-MHE patients presented lower FC between the L-presubiculum and L-precuneus than C-NMHE patients. Compared to controls, C-MHE patients had reduced FC between L-presubiculum and subiculum seeds and bilateral precuneus, which correlated with cognitive impairment and memory performance. Alterations in the FC of the hippocampal system could contribute to learning and long-term memory impairments in C-MHE patients. This study demonstrates the association between alterations in learning and long-term memory and structural and FC disturbances in hippocampal structures in cirrhotic patients.

  13. Reducing Mouse Anxiety during Handling: Effect of Experience with Handling Tunnels

    PubMed Central

    Gouveia, Kelly; Hurst, Jane L.

    2013-01-01

    Handling stress is a well-recognised source of variation in animal studies that can also compromise the welfare of research animals. To reduce background variation and maximise welfare, methods that minimise handling stress should be developed and used wherever possible. Recent evidence has shown that handling mice by a familiar tunnel that is present in their home cage can minimise anxiety compared with standard tail handling. As yet, it is unclear whether a tunnel is required in each home cage to improve response to handling. We investigated the influence of prior experience with home tunnels among two common strains of laboratory mice: ICR(CD-1) and C57BL/6. We compared willingness to approach the handler and anxiety in an elevated plus maze test among mice picked up by the tail, by a home cage tunnel or by an external tunnel shared between cages. Willingness to interact with the handler was much greater for mice handled by a tunnel, even when this was unfamiliar, compared to mice picked up by the tail. Once habituated to handling, C57BL/6 mice were most interactive towards a familiar home tunnel, whereas the ICR strain showed strong interaction with all tunnel handling regardless of any experience of a home cage tunnel. Mice handled by a home cage or external tunnel showed less anxiety in an elevated plus maze than those picked up by the tail. This study shows that using a tunnel for routine handling reduces anxiety among mice compared to tail handling regardless of prior familiarity with tunnels. However, as home cage tunnels can further improve response to handling in some mice, we recommend that mice are handled with a tunnel provided in their home cage where possible as a simple practical method to minimise handling stress. PMID:23840458

  14. Reducing mouse anxiety during handling: effect of experience with handling tunnels.

    PubMed

    Gouveia, Kelly; Hurst, Jane L

    2013-01-01

    Handling stress is a well-recognised source of variation in animal studies that can also compromise the welfare of research animals. To reduce background variation and maximise welfare, methods that minimise handling stress should be developed and used wherever possible. Recent evidence has shown that handling mice by a familiar tunnel that is present in their home cage can minimise anxiety compared with standard tail handling. As yet, it is unclear whether a tunnel is required in each home cage to improve response to handling. We investigated the influence of prior experience with home tunnels among two common strains of laboratory mice: ICR(CD-1) and C57BL/6. We compared willingness to approach the handler and anxiety in an elevated plus maze test among mice picked up by the tail, by a home cage tunnel or by an external tunnel shared between cages. Willingness to interact with the handler was much greater for mice handled by a tunnel, even when this was unfamiliar, compared to mice picked up by the tail. Once habituated to handling, C57BL/6 mice were most interactive towards a familiar home tunnel, whereas the ICR strain showed strong interaction with all tunnel handling regardless of any experience of a home cage tunnel. Mice handled by a home cage or external tunnel showed less anxiety in an elevated plus maze than those picked up by the tail. This study shows that using a tunnel for routine handling reduces anxiety among mice compared to tail handling regardless of prior familiarity with tunnels. However, as home cage tunnels can further improve response to handling in some mice, we recommend that mice are handled with a tunnel provided in their home cage where possible as a simple practical method to minimise handling stress.

  15. Protective effect of Heliotropium eichwaldi against cisplatin-induced nephrotoxicity in mice.

    PubMed

    Sharma, Surendra Kr; Goyal, Naveen

    2012-05-01

    The aim of the present study was to evaluate the nephroprotective effect of methanolic extract of Heliotropium eichwaldii (MHE) in mice with cisplatin-induced acute renal damage. Nephrotoxicity was induced by a single intraperitoneal injection of cisplatin (16mg/kg). Swiss albino mice were injected with vehicle, cisplatin, cisplatin plus MHE 200 mg/kg and cisplatin plus MHE 400mg/kg, respectively. MHE was administered for 7 d at a dose of 200 and 400 mg/kg per day orally starting 4 d before cisplatin injection. Animals were sacrificed 3d after treatment and blood as well as kidney tissue was isolated and analyzed. The various parameters such as blood urea nitrogen (BUN), serum creatinine (CRE), malondialdehyde (MDA), and catalase (CAT) and superoxide dismutase (SOD) activities were analyzed. MHE treatment significantly reduced BUN and serum CRE levels elevated by cisplatin administration (P<0.05). Also, it significantly attenuated cisplatin-induced increase in MDA level and improved the decreased CAT and SOD activities in renal cortical homogenates (P<0.05). Additionally, histopathological examination and scoring showed that MHE markedly ameliorated cisplatin-induced renal tubular necrosis. MHE can be considered a potential candidate for protection of nephrotoxicity induced by cisplatin.

  16. High level radioactive waste vitrification process equipment component testing

    NASA Astrophysics Data System (ADS)

    Siemens, D. H.; Health, W. C.; Larson, D. E.; Craig, S. N.; Berger, D. N.; Goles, R. W.

    1985-04-01

    Remote operability and maintainability of vitrification equipment were assessment under shielded cell conditions. The equipment tested will be applied to immobilize high level and transuranic liquid waste slurries that resulted from plutonium production for defense weapons. Equipment tested included: a turntable for handling waste canisters under the melter; a removable discharge cone in the melter overflow section; a thermocouple jumper that extends into a shielded cell; remote instrument and electrical connectors; remote, mechanical, and heat transfer aspects of the melter glass overflow section; a reamer to clean out plugged nozzles in the melter top; a closed circuit camera to view the melter interior; and a device to retrieve samples of the glass product. A test was also conduucted to evaluate liquid metals for use in a liquid metal sealing system.

  17. Safe handling of cytotoxic compounds in a biopharmaceutical environment.

    PubMed

    Hensgen, Miriam I; Stump, Bernhard

    2013-01-01

    Handling cytotoxic drugs such as antibody-drug conjugates (ADCs) in a biopharmaceutical environment represents a challenge based on the potency of the compounds. These derivatives are dangerous to humans if they accidentally get in contact with the skin, are inhaled, or are ingested, either as pure compounds in their solid state or as a solution dissolved in a co-solvent. Any contamination of people involved in the manufacturing process has to be avoided. On the other hand, biopharmaceuticals need to be protected simultaneously against any contamination from the manufacturing personnel. Therefore, a tailor-made work environment is mandatory in order to manufacture ADCs. This asks for appropriate technical equipment to keep potential hazardous substances contained. In addition, clearly defined working procedures based on risk assessments as well as proper training for all personnel involved in the manufacturing process are needed to safely handle these highly potent pharmaceuticals.

  18. Gender difference in safe and unsafe practice of pesticide handling in tobacco farmers of malaysia.

    PubMed

    Bin Nordin, R; Araki, S; Sato, H; Yokoyama, K; Bin Wan Muda, W A; Win Kyi, D

    2001-01-01

    To identify gender difference in safe and unsafe practice of pesticide handling in tobacco farmers of Malaysia, we conducted a 20-item questionnaire interview on storage of pesticide (4 questions), mixing of pesticide (3 questions), use of personal protective equipment and clothing while spraying pesticide (7 questions), activities during and after spraying of pesticide (5 questions), and maintenance of pesticide sprayer (1 question) in 496 tobacco farmers (395 males and 101 females) in Bachok District, Kelantan, Malaysia. Duration of employment was significantly longer in females than those in males (p<0.001). In addition, proportion with no formal education in females was significantly higher than those in males (p<0.05). The following eight common factors were extracted from the 20 questionnaires by principal components factor analysis after varimax rotation in all farmers: (1) use of personal protective equipment, (2) unsafe work habit, (3) reading and following instructions on pesticide label, (4) security, storage and disposal of pesticide container, (5) safe work habit, (6) proper handling of pesticide and maintenance of pesticide sprayer, (7) use of personal protective clothing, and (8) safe handling of pesticide. Results of analysis of covariance for the eight factor scores of all male and female farmers, controlling for educational level and duration of employment, showed that: (1) factor scores for use of personal protective equipment (p<0.001), use of personal protective clothing (p<0.001) and safe work habit (p<0.001) in females were significantly lower than those in males; (2) conversely, factor scores for reading and following instruction on pesticide label (p<0.001) and proper handling of pesticide and maintenance of pesticide sprayer (p<0.01) in males were significantly lower than those in females; and (3) there were no significant differences in other three factor scores (p>0.05). We therefore conclude that: (1) for female tobacco farmers, choice

  19. Gender Difference in Safe and Unsafe Practice of Pesticide Handling in Tobacco Farmers of Malaysia

    PubMed Central

    BIN NORDIN, Rusli; ARAKI, Shunichi; SATO, Hajime; YOKOYAMA, Kazuhito; BIN WAN MUDA, Wan Abdul Manan; WIN KYI, Daw

    2001-01-01

    To identify gender difference in safe and unsafe practice of pesticide handling in tobacco farmers of Malaysia, we conducted a 20-item questionnaire interview on storage of pesticide (4 questions), mixing of pesticide (3 questions), use of personal protective equipment and clothing while spraying pesticide (7 questions), activities during and after spraying of pesticide (5 questions), and maintenance of pesticide sprayer (1 question) in 496 tobacco farmers (395 males and 101 females) in Bachok District, Kelantan, Malaysia. Duration of employment was significantly longer in females than those in males (p<0.001). In addition, proportion with no formal education in females was significantly higher than those in males (p<0.05). The following eight common factors were extracted from the 20 questionnaires by principal components factor analysis after varimax rotation in all farmers: (1) use of personal protective equipment, (2) unsafe work habit, (3) reading and following instructions on pesticide label, (4) security, storage and disposal of pesticide container, (5) safe work habit, (6) proper handling of pesticide and maintenance of pesticide sprayer, (7) use of personal protective clothing, and (8) safe handling of pesticide. Results of analysis of covariance for the eight factor scores of all male and female farmers, controlling for educational level and duration of employment, showed that: (1) factor scores for use of personal protective equipment (p<0.001), use of personal protective clothing (p<0.001) and safe work habit (p<0.001) in females were significantly lower than those in males; (2) conversely, factor scores for reading and following instruction on pesticide label (p<0.001) and proper handling of pesticide and maintenance of pesticide sprayer (p<0.01) in males were significantly lower than those in females; and (3) there were no significant differences in other three factor scores (p>0.05). We therefore conclude that: (1) for female tobacco farmers, choice

  20. Documentation forms for monitoring occupational surveillance of healthcare workers who handle cytotoxic drugs.

    PubMed

    Parillo, V L

    1994-01-01

    To develop a procedure for medical surveillance of healthcare workers who handle cytotoxic drugs. Literature review and guidelines published by the Occupational Safety and Health Administration and the National Institute for Occupational Safety and Health. INFORMATION SELECTION: Studies of possible exposure screening tests, congenital defects in offspring, and case studies. Some degree of risk exists in handling cytotoxic drugs, but no reliable screening test for cytotoxic drug exposure has been developed. Reproductive hazards are possible when protective equipment is not used. Areas to be addressed when devising surveillance procedures include who to cover, what baseline data to gather, what periodic monitoring will be necessary (and at what interval it will be conducted), how to handle exposure incidents, and what documentation system will be used. A procedure using a baseline risk factor form and a yearly monitoring questionnaire was devised and implemented. Forms contain documentation of worker teaching. Most often, nurses are the healthcare workers who handle cytotoxic drugs. A consistent approach to monitoring healthcare workers is facilitated by using a defined procedure and standardized forms.

  1. Factors influencing oncology nurses' use of hazardous drug safe-handling precautions.

    PubMed

    Polovich, Martha; Clark, Patricia C

    2012-05-01

    To examine relationships among factors affecting nurses' use of hazardous drug (HD) safe-handling precautions, identify factors that promote or interfere with HD precaution use, and determine managers' perspectives on the use of HD safe-handling precautions. Cross-sectional, mixed methods; mailed survey to nurses who handle chemotherapy and telephone interviews with managers. Mailed invitation to oncology centers across the United States. 165 nurses who reported handling chemotherapy and 20 managers of nurses handling chemotherapy. Instruments measured the use of HD precautions and individual and organizational factors believed to influence precaution use. Data analysis included descriptive statistics and hierarchical regression. Manager interview data were analyzed using content analysis. Chemotherapy exposure knowledge, self-efficacy, perceived barriers, perceived risk, interpersonal influences, and workplace safety climate. Nurses were well educated, experienced, and certified in oncology nursing. The majority worked in outpatient settings and administered chemotherapy to an average of 6.8 patients per day. Exposure knowledge, self-efficacy for using personal protective equipment, and perceived risk of harm from HD exposure were high; total precaution use was low. Nurse characteristics did not predict HD precaution use. Fewer barriers, better workplace safety climate, and fewer patients per day were independent predictors of higher HD precaution use. HD handling policies were present, but many did not reflect current recommendations. Few managers formally monitored nurses' HD precaution use. Circumstances in the workplace interfere with nurses' use of HD precautions. Interventions should include fostering a positive workplace safety climate, reducing barriers, and providing appropriate nurse-patient ratios.

  2. Minimal hepatic encephalopathy matters in daily life

    PubMed Central

    Bajaj, Jasmohan S

    2008-01-01

    Minimal hepatic encephalopathy is a neuro-cognitive dysfunction which occurs in an epidemic proportion of cirrhotic patients, estimated as high as 80% of the population tested. It is characterized by a specific, complex cognitive dysfunction which is independent of sleep dysfunction or problems with overall intelligence. Although named “minimal”, minimal hepatic encephalopathy (MHE) can have a far-reaching impact on quality of life, ability to function in daily life and progression to overt hepatic encephalopathy. Importantly, MHE has a profound negative impact on the ability to drive a car and may be a significant factor behind motor vehicle accidents. A crucial aspect of the clinical care of MHE patients is their driving history, which is often ignored in routine care and can add a vital dimension to the overall disease assessment. Driving history should be an integral part of care in patients with MHE. The lack of specific signs and symptoms, the preserved communication skills and lack of insight make MHE a difficult condition to diagnose. Diagnostic strategies for MHE abound, but are usually limited by financial, normative or time constraints. Recent studies into the inhibitory control and critical flicker frequency tests are encouraging since these tests can increase the rates of MHE diagnosis without requiring a psychologist. Although testing for MHE and subsequent therapy is not standard of care at this time, it is important to consider this in cirrhotics in order to improve their ability to live their life to the fullest. PMID:18595126

  3. NASA/ESA CV-990 Spacelab simulation. Appendixes: C, data-handling: Planning and implementation; D, communications; E, mission documentation

    NASA Technical Reports Server (NTRS)

    Reller, J. O., Jr.

    1976-01-01

    Data handling, communications, and documentation aspects of the ASSESS mission are described. Most experiments provided their own data handling equipment, although some used the airborne computer for backup, and one experiment required real-time computations. Communications facilities were set up to simulate those to be provided between Spacelab and the ground, including a downlink TV system. Mission documentation was kept to a minimum and proved sufficient. Examples are given of the basic documents of the mission.

  4. The impact of drywall handling tools on the low back.

    PubMed

    Hess, Jennifer A; Kincl, Laurel D; Davis, Kermit

    2010-03-01

    Carpenters and other construction workers who install drywall have high rates of strains and sprains to the low back and shoulder. Drywall is heavy and awkward to handle resulting in increased risk of injury. The purpose of this study was to evaluate several low-cost coupling tools that have the potential to reduce awkward postures in drywall installers. Five coupling tools were evaluated using the Lumbar Motion Monitor that measures trunk kinematics and predicts probability of low back disorder group membership risk (LBD risk). Workers answered surveys about their comfort while using each tool. The results indicate that use of the 2-person manual lift and the J-handle provide the best reduction in awkward postures, motions, low back sagittal moment, and LBD risk. The two-person manual lift appears to be the safest method of lifting and moving drywall, though using the two-person J-handle also significantly reduces injury risk. Given that carpenters are skeptical about using equipment that can get in the way or get lost, a practical recommendation is promotion of two-person manual lifting. For single-person lifts, the Old Man tool is a viable option to decrease risk of MSDs.

  5. Sprag Handle Wrenches

    NASA Technical Reports Server (NTRS)

    Vranishm, John M.

    2010-01-01

    Sprag handle wrenches have been proposed for general applications in which conventional pawl-and-ratchet wrenches and sprag and cam "clickless" wrenches are now used. Sprag handle wrenches are so named because they would include components that would function both as parts of handles and as sprags (roller locking/unlocking components). In comparison with all of the aforementioned conventional wrenches, properly designed sprag handle wrenches could operate with much less backlash; in comparison with the conventional clickless wrenches, sprag handle wrenches could be stronger and less expensive (because the sprags would be larger and more easily controllable than are conventional sprags and cams).

  6. Minimal hepatic encephalopathy in patients with cirrhosis by measuring liver stiffness and hepatic venous pressure gradient.

    PubMed

    Sharma, Praveen; Kumar, Ashish

    2012-01-01

    Transient elastography (TE) of liver and hepatic venous pressure gradient (HVPG) allows accurate prediction of cirrhosis and its complications in patients with chronic liver disease. There is no study on prediction of minimal hepatic encephalopathy (MHE) using TE and HVPG in patients with cirrhosis. Consecutive cirrhotic patients who never had an episode of hepatic encephalopathy (HE) were enrolled. All patients were assessed by psychometry (number connection test (NCT-A and B), digit symbol test (DST), serial dot test (SDT), line tracing test (LTT)), critical flicker frequency test (CFF), TE by FibroScan and HVPG. MHE was diagnosed if there were two or more abnormal psychometry tests (± 2 SD controls). 150 patients with cirrhosis who underwent HVPG were screened; 91 patients (61%, age 44.0 ± 11.4 years, M:F:75:16, Child's A:B:C 18:54:19) met the inclusion criteria. Fifty three (58%) patients had MHE (Child A (7/18, 39%), Child B (32/54, 59%) and Child C (14/19, 74%)). There was no significant difference between alanine aminotranferease (ALT), aspartate aminotransferase (AST) and total bilirubin level in patients with MHE versus non MHE. Patients with MHE had significantly lower CFF than non MHE patients (38.4 ± 3.0 vs. 40.2 ± 2.2 Hz, P = 0.002). TE and HVPG in patients with MHE did not significantly differ from patients with no MHE (30.9 ± 17.2 vs. 29.8 ± 18.2 KPas, P = 0.78; and 13.6 ± 2.7 vs. 13.6 ± 3.2 mmHg, P = 0.90, respectively).There was significant correlation of TE with Child's score (0.25, P = 0.01), MELD (0.40, P = 0.001) and HVPG (0.72, P = 0.001) while no correlation with psychometric tests, CFF and MHE. TE by FibroScan and HVPG cannot predict minimal hepatic encephalopathy in patients with cirrhosis.

  7. Transportation and handling loads

    NASA Technical Reports Server (NTRS)

    Ostrem, F. E.

    1971-01-01

    Criteria and recommended practices are presented for the prediction and verification of transportation and handling loads for the space vehicle structure and for monitoring these loads during transportation and handling of the vehicle or major vehicle segments. Elements of the transportation and handling systems, and the forcing functions and associated loads are described. The forcing functions for common carriers and typical handling devices are assessed, and emphasis is given to the assessment of loads at the points where the space vehicle is supported during transportation and handling. Factors which must be considered when predicting the loads include the transportation and handling medium; type of handling fixture; transport vehicle speed; types of terrain; weather (changes in pressure of temperature, wind, etc.); and dynamics of the transportation modes or handling devices (acceleration, deceleration, and rotations of the transporter or handling device).

  8. Prevalence of minimal hepatic encephalopathy and quality of life in patients with decompensated cirrhosis.

    PubMed

    Mina, Aline; Moran, Segundo; Ortiz-Olvera, Nayeli; Mera, Robertino; Uribe, Misael

    2014-10-01

    Minimal hepatic encephalopathy (MHE) affects more than 30% of patients with cirrhosis, and it has been suggested that despite no recognizable clinical symptoms of neurological abnormalities, it may affect health-related quality of life (HRQL); however, this fact remains controversial. The aim of our study was to evaluate the prevalence of MHE and HRQL in patients diagnosed with decompensated cirrhosis. Patients with liver cirrhosis were selected independent of the etiology of the disease. All patients underwent a complete clinical history, and only patients with decompensated hepatic cirrhosis were included. Psychometric tests were applied to evaluate the presence of MHE along with the Chronic Liver Disease Questionnaire. Appetite was measured by verbal and visual analog scales. One hundred and twenty-five patients were included with a median age of 56.0 years. They were classified according to the Child-Pugh index as A, (n = 56), B, (n = 51) and C (n = 18). Prevalence of MHE was 44.0% (n = 55). In patients with MHE, a significant reduction was observed in domains of activity (3.3 [2.0] vs 4.8 [2.8]), fatigue (3.2 [2.0] vs 3.9 [2.3]), systemic symptoms (3.8 [2.0] vs 4.8 [1.7]), emotional function (3.6 [1.9] vs 4.0 [1.9]) and global scoring (3.7 [1.7] vs 4.3 [1.8]) when compared with non-MHE patients (n = 70). Twenty-two percent of the patients with MHE reported little appetite compared with 11% in the non-MHE group. The results suggest that MHE and a reduction in appetite are associated with deterioration in HRQL in patients with decompensated cirrhosis. © 2013 The Japan Society of Hepatology.

  9. A new virtual-reality training module for laparoscopic surgical skills and equipment handling: can multitasking be trained? A randomized controlled trial.

    PubMed

    Bongers, Pim J; Diederick van Hove, P; Stassen, Laurents P S; Dankelman, Jenny; Schreuder, Henk W R

    2015-01-01

    During laparoscopic surgery distractions often occur and multitasking between surgery and other tasks, such as technical equipment handling, is a necessary competence. In psychological research, reduction of adverse effects of distraction is demonstrated when specifically multitasking is trained. The aim of this study was to examine whether multitasking and more specifically task-switching can be trained in a virtual-reality (VR) laparoscopic skills simulator. After randomization, the control group trained separately with an insufflator simulation module and a laparoscopic skills exercise module on a VR simulator. In the intervention group, insufflator module and VR skills exercises were combined to develop a new integrated training in which multitasking was a required competence. At random moments, problems with the insufflator appeared and forced the trainee to multitask. During several repetitions of a different multitask VR skills exercise as posttest, performance parameters (laparoscopy time, insufflator time, and errors) were measured and compared between both the groups as well with a pretest exercise to establish the learning effect. A face-validity questionnaire was filled afterward. University Medical Centre Utrecht, The Netherlands. Medical and PhD students (n = 42) from University Medical Centre Utrecht, without previous experience in laparoscopic simulation, were randomly assigned to either intervention (n = 21) or control group (n = 21). All participants performed better in the posttest exercises without distraction of the insufflator compared with the exercises in which multitasking was necessary to solve the insufflator problems. After training, the intervention group was significantly quicker in solving the insufflator problems (mean = 1.60Log(s) vs 1.70Log(s), p = 0.02). No significant differences between both the groups were seen in laparoscopy time and errors. Multitasking has negative effects on the laparoscopic performance. This study suggests

  10. Probiotic and lactulose: influence on gastrointestinal flora and pH value in minimal hepatic encephalopathy rats.

    PubMed

    Jiang, Shu-Man; Jia, Lin; Zhang, Mei-Hua

    2015-01-01

    The present study was conducted to investigate the influence on gastrointestinal flora, counts of bifidobacteria and Enterobacterceae in colon and pH value of gastrointestinal after lactulose and probiotic treatment on rat experimental minimal hepatic encephalopathy (MHE) induced by thioactamide (TAA). MHE was induced by intraperitoneal injection of TAA. 48 male MHE models were then randomly divided into 4 groups: control group (n = 12); MHE group (n = 12) received tap water ad libitum only; lactulose group (n = 12) and probiotics group (n = 12) gavaged respectively with 8 ml/kg of lactulose and 1.5 g/kg of probiotic preparation Golden Bifid (highly concentrated combination probiotic) dissolved in 2 ml of normal saline, once a day for 8 days. The latency of Brainstem auditory evoked potentials (BAEP) I was used as objective index of MHE. Counts of gastrointestinal flora, counts of bifidobacteria and Enterobacterceae in colon and pH value of gastrointestinal were examined respectively. Compared to MHE group, counts of gastrointestinal flora has greatly decreased, ratio of bifidobacteria and Enterobacterceae has greatly increased, pH value of colon has greatly descended (P < 0.05). However, there was no significant difference between lactulose group and probiotic group (P > 0.05). Both lactulose and probiotics can effectively prevent bacteria translocation and overgrowth, intensify CR, improved value of B/E, and acidify intestinal, decreased pH value of colon. Probiotic compound Golden Bifid is as useful as lactulose for the prevention and treatment of MHE. Probiotic therapy may be a safe, natural, well-tolerated therapy appropriate for the long-term treatment of MHE.

  11. Looking south through east portion of Centralized Work Equipment (C.W.E.) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Looking south through east portion of Centralized Work Equipment (C.W.E.) Storage Shed (Bldg. 126). Note overhead monorails for material-handling hoists. This shed stored track maintenance materials - Atchison, Topeka, Santa Fe Railroad, Albuquerque Shops, C.W.E. Storage Shed, 908 Second Street, Southwest, Albuquerque, Bernalillo County, NM

  12. Using operational equipment to read accident dosemeters.

    PubMed

    Devine, R T; Vigil, M M; Martinez, W A

    2004-01-01

    Analysis of accident dosemeters usually involves the use of laboratory-based counting equipment. Gamma spectrometers are used for indium, copper and gold, and alpha-beta detectors for sulphur. This equipment is usually not easily transported due to the shielding required and the weight and delicacy of the counters. For intercomparison studies that require reading the dosemeters on site, a transportable system is required unless the site operating the study can count samples for all the participants. In the case of an actual accident these systems would have a difficulty in counting a large number of accident dosemeters. In an accident, personnel are usually subdivided according to their level of exposure. Those exposed to higher doses are treated immediately. An alternate system should be made available to handle the dosemeters worn by those personnel are likely to receive lower doses. Improvements in portable operational equipment for gamma and beta monitoring allow their use as spectrometers. Such a system was used for the SILENE intercomparison conducted at IRSN Valduc on 12 June and 19, 2002, and the preliminary results compared well with the other participants.

  13. 78 FR 26110 - Kicking Cars and Going Between Rolling Equipment During Flat Switching Operations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-03

    ... Cars and Going Between Rolling Equipment During Flat Switching Operations AGENCY: Federal Railroad... occurred during a railroad switching operation that involved a railroad employee kicking cars and... make recommendations to railroads regarding the adoption of car-handling procedures during flat...

  14. A pilot study using lactulose in management of minimal hepatic encephalopathy in children with extrahepatic portal vein obstruction.

    PubMed

    El-Karaksy, Hanaa Mostafa; Afifi, Omneya; Bakry, Azza; Kader, Ann Abdel; Saber, Noha

    2017-02-01

    Minimal hepatic encephalopathy (MHE) is not associated with overt neuropsychiatric symptoms but rather with subtle changes in psychometric and/or neurophysiologic tests. We aimed to diagnose MHE in children with extrahepatic portal vein obstruction (EHPVO) and to evaluate the effect of lactulose on MHE. A prospective study was carried out on 30 patients with EHPVO (21 males; mean age 10±2.5 years). The study was carried out in the Pediatric Hepatology Unit, Cairo University Pediatric Hospital, Cairo, Egypt, between 2011 and 2013. All patients were subjected to clinical and laboratory assessment, neuropsychmetric testing using the arabic version of Wechsler intelligence tests, neurophysiological testing by visual electroencephalogram and P300 event related potentials (ERP). The prevalence of MHE among children with EHPVO was 20% (6/30). After randomization to treatment and no-treatment groups using lactulose, all tests were repeated after three months. Among four patients with MHE who received lactulose, three (75%) improved. On the other hand, one of the patients in the no-treatment group developed MHE. Only one patient in the treatment arm had to discontinue lactulose because of severe diarrhea. This pilot study revealed that the prevalence of MHE was 20%. Improvement on psychometic tests was seen in 75% of our patients (3/4) after treatment with lactulose. Lactulose treatment was well tolerated.

  15. Differences among nursing homes in outcomes of a safe resident handling program

    PubMed Central

    Kurotvski, Alicia; Gore, Rebecca; Buchholz, Bryan; Punnett, Laura

    2018-01-01

    A large nursing home corporation implemented a safe resident handling program (SRHP) in 2004–2007. We evaluated its efficacy over a 2-year period by examining differences among 5 centers in program outcomes and potential predictors of those differences. We observed nursing assistants (NAs), recording activities and body postures at 60-second intervals on personal digital assistants at baseline and at 3-month, 12-month, and 24-month follow-ups. The two outcomes computed were change in equipment use during resident handling and change in a physical workload index that estimated spinal loading due to body postures and handled loads. Potential explanatory factors were extracted from post-observation interviews, investigator surveys of the workforce, from administrative data, and employee satisfaction surveys. The facility with the most positive outcome measures was associated with many positive changes in explanatory factors and the facility with the fewest positive outcome measures experienced negative changes in the same factors. These findings suggest greater SRHP benefits where there was lower NA turnover and agency staffing; less time pressure; and better teamwork, staff communication, and supervisory support. PMID:22833329

  16. Implementation and adoption of mechanical patient lift equipment in the hospital setting: The importance of organizational and cultural factors.

    PubMed

    Schoenfisch, Ashley L; Myers, Douglas J; Pompeii, Lisa A; Lipscomb, Hester J

    2011-12-01

    Work focused on understanding implementation and adoption of interventions designed to prevent patient-handling injuries in the hospital setting is lacking in the injury literature and may be more insightful than more traditional evaluation measures. Data from focus groups with health care workers were used to describe barriers and promoters of the adoption of patient lift equipment and a shift to a "minimal-manual lift environment" at two affiliated hospitals. Several factors influencing the adoption of the lift equipment and patient-handling policy were noted: time, knowledge/ability, staffing, patient characteristics, and organizational and cultural aspects of work. The adoption process was complex, and considerable variability by hospital and across units was observed. The use of qualitative data can enhance the understanding of factors that influence implementation and adoption of interventions designed to prevent patient-handling injuries among health care workers. Copyright © 2011 Wiley Periodicals, Inc.

  17. Process technology and effects of spallation products: Circuit components, maintenance, and handling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sigg, B.; Haines, S.J.; Dressler, R.

    1996-06-01

    Working Session D included an assessment of the status of the technology and components required to: (1) remove impurities from the liquid metal (mercury or Pb-Bi) target flow loop including the effects of spallation products, (2) provide the flow parameters necessary for target operations, and (3) maintain the target system. A series of brief presentations were made to focus the discussion on these issues. The subjects of these presentations, and presenters were: (1) Spallation products and solubilities - R. Dressler; (2) Spallation products for Pb-Bi - Y. Orlov; (3) Clean/up/impurity removal components - B. Sigg; (4) {open_quotes}Road-Map{close_quotes} and remote handlingmore » needs - T. McManamy; (5) Remote handling issues and development - M. Holding. The overall conclusion of this session was that, with the exception of (i) spallation product related processing issues, (ii) helium injection and clean-up, and (iii) specialized remote handling equipment, the technology for all other circuit components (excluding the target itself) exists. Operating systems at the Institute of Physics in Riga, Latvia (O. Lielausis) and at Ben-Gurion University in Beer Shiva, Israel (S. Lesin) have demonstrated that other liquid metal circuit components including pumps, heat exchangers, valves, seals, and piping are readily available and have been reliably used for many years. In the three areas listed above, the designs and analysis are not judged to be mature enough to determine whether and what types of technology development are required. Further design and analysis of the liquid metal target system is therefore needed to define flow circuit processing and remote handling equipment requirements and thereby identify any development needs.« less

  18. Optical system for UV-laser technological equipment

    NASA Astrophysics Data System (ADS)

    Fedosov, Yuri V.; Romanova, Galina E.; Afanasev, Maxim Ya.

    2017-09-01

    Recently there has been an intensive development of intelligent industrial equipment that is highly automated and can be rapidly adjusted for certain details. This equipment can be robotics systems, automatic wrappers and markers, CNC machines and 3D printers. The work equipment considered is the system for selective curing of photopolymers using a UV-laser and UV-radiation in such equipment that leads to additional technical difficulties. In many cases for transporting the radiation from the laser to the point processed, a multi-mirror system is used: however, such systems are usually difficult to adjust. Additionally, such multi-mirror systems are usually used as a part of the equipment for laser cutting of metals using high-power IR-lasers. For the UV-lasers, using many mirrors leads to crucial radiation losses because of many reflections. Therefore, during the development of the optical system for technological equipment using UV-laser we need to solve two main problems: to transfer the radiation for the working point with minimum losses and to include the system for controlling/handling the radiation spot position. We introduce a system for working with UV-lasers with 450mW of power and a wavelength of 0.45 μm based on a fiber system. In our modelling and design, we achieve spot sizes of about 300 μm, and the designed optical and mechanical systems (prototypes) were manufactured and assembled. In this paper, we present the layout of the technological unit, the results of the theoretical modelling of some parts of the system and some experimental results.

  19. Rifaximin vs. lactulose in treatment of minimal hepatic encephalopathy.

    PubMed

    Sidhu, Sandeep S; Goyal, Omesh; Parker, Richard A; Kishore, Harsh; Sood, Ajit

    2016-03-01

    Lactulose and rifaximin have already been shown to improve both cognitive functions and health related quality of life (HRQOL) in MHE patients. We aimed to compare the efficacy of rifaximin with lactulose in reversal of MHE and improvement in HRQOL in cirrhotic patients with MHE. This prospective, randomized, open label, non-inferiority trial, was conducted at the Gastroenterology department of a tertiary care institute in Northern India. MHE was diagnosed if any two of the five neuro-psychometric (NP) tests were positive. HRQOL was assessed using the sickness impact profile (SIP) questionnaire (John Hopkins University, USA). Of 527 cirrhotics screened, 351 were found eligible and tested for MHE. A total of 112 (31.9%) patients were found to have MHE and then randomized into two groups group A (lactulose; 30-120 ml/day) and B (Tablet. rifaximin; 400 mg thrice a day). Based on the intention-to-treat population, the proportion of patients with MHE reversal at 3 months was 73.7% (42/57) in the rifaximin arm and 69.1% (38/55) in the lactulose arm [4.6% difference (90% CI -9.3% to 18.4%)]. However, non-inferiority of rifaximin over lactulose could not be established as the pre-specified non-inferiority margin (-5%) lies within the two-sided 90% confidence interval of the difference. HRQOL was significantly improved in both groups (P = 0.20). However, the proportion of patients with flatulence (P = 0.004) and diarrhoea (P = 0.0002) was significantly higher in patients who took lactulose. Non-inferiority of rifaximin over lactulose for MHE reversal was not established. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  20. The burden of minimal hepatic encephalopathy: from diagnosis to therapeutic strategies

    PubMed Central

    Ridola, Lorenzo; Cardinale, Vincenzo; Riggio, Oliviero

    2018-01-01

    Minimal hepatic encephalopathy (MHE) is the mildest form of hepatic encephalopathy (HE). It affects the performance of psychometric tests focused on attention, working memory, psychomotor speed, and visuospatial ability, as well as electrophysiological and other functional brain measures. MHE is a frequent complication of liver disease, affecting up to 80% of tested patients. By being related to falls, an impairment in fitness to drive and the development of overt HE, MHE severely affects the lives of patients and caregivers by altering their quality of life and their socioeconomic status. MHE is detected in clinically asymptomatic patients using appropriate psychometric tests and neurophysiological methods that highlight neuropsychological alterations, such as video-spatial orientation deficits, attention disorders, memory, reaction times, electroencephalogram slowing, prolongation of latency-evoked cognitive potentials, and reduction in the critical flicker frequency. Several treatments have been proposed for MHE treatment, including non-absorbable disaccharides, poorly absorbable antibiotics such as rifaximin, probiotics and branched-chain amino acids. However, because of the multiple diagnosis methods, the various endpoints of treatment trials and the variety of agents used in trials, the treatment of MHE is not currently recommended as routine, but only on a case-by-case basis. PMID:29507462

  1. Mixed Oxide Fresh Fuel Package Auxiliary Equipment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yapuncich, F.; Ross, A.; Clark, R.H.

    2008-07-01

    The United States Department of Energy's National Nuclear Security Administration (NNSA) is overseeing the construction the Mixed Oxide (MOX) Fuel Fabrication Facility (MFFF) on the Savannah River Site. The new facility, being constructed by NNSA's contractor Shaw AREVA MOX Services, will fabricate fuel assemblies utilizing surplus plutonium as feedstock. The fuel will be used in designated commercial nuclear reactors. The MOX Fresh Fuel Package (MFFP), which has recently been licensed by the Nuclear Regulatory Commission (NRC) as a type B package (USA/9295/B(U)F-96), will be utilized to transport the fabricated fuel assemblies from the MFFF to the nuclear reactors. It wasmore » necessary to develop auxiliary equipment that would be able to efficiently handle the high precision fuel assemblies. Also, the physical constraints of the MFFF and the nuclear power plants require that the equipment be capable of loading and unloading the fuel assemblies both vertically and horizontally. The ability to reconfigure the load/unload evolution builds in a large degree of flexibility for the MFFP for the handling of many types of both fuel and non fuel payloads. The design and analysis met various technical specifications including dynamic and static seismic criteria. The fabrication was completed by three major fabrication facilities within the United States. The testing was conducted by Sandia National Laboratories. The unique design specifications and successful testing sequences will be discussed. (authors)« less

  2. Handling and restraint.

    PubMed

    Donovan, John; Brown, Patricia

    2006-07-01

    For the safety of the handler and the animal, proper methods for handling and restraining laboratory animals should be followed. Improper handling can result in increased stress and injury to the animal. In addition, the handler risks injury from bite wounds or scratches inflicted when the animal becomes fearful or anxious. By using sure, direct movements with a determined attitude, the animal can be easily handled and restrained. Animals can be restrained either manually or in a plastic restrainer. The protocols in this unit describe handling and manual restraint of mice, rats, hamsters, and rabbits. Alternate protocols describe restraint using the plastic restrainer.

  3. Handling and restraint.

    PubMed

    Donovan, John; Brown, Patricia

    2004-09-01

    For the safety of the handler and the animal, proper methods for handling and restraining laboratory animals should be followed. Improper handling can result in increased stress and injury to the animal. In addition, the handler risks injury from bite wounds or scratches inflicted when the animal becomes fearful or anxious. By using sure, direct movements with a determined attitude, the animal can be easily handled and restrained. Animals can be restrained either manually or in a plastic restrainer. The protocols in this unit describe handling and manual restraint of mice, rats, hamsters, and rabbits. Alternate protocols describe restraint using the plastic restrainer.

  4. Texas passes first law for safe patient handling in America: landmark legislation protects health-care workers and patients from injury related to manual patient lifting.

    PubMed

    Hudson, Mary Anne

    2005-01-01

    On June 17,2005, Texas Governor Rick Perry (R) signed into law Senate Bill 1525, making Texas the first state in the nation to require hospitals and nursing homes to implement safe patient handling and movement programs. Governor Perry is to be commended for this heroic first stand for safe patient handling in America. The landmark legislation will take effect January 1, 2006, requiring the establishment of policy to identify, assess, and develop methods of controlling the risk of injury to patients and nurses associated with lifting, transferring, repositioning, and movement of patients; evaluation of alternative methods from manual lifting to reduce the risk of injury from patient lifting, including equipment and patient care environment; restricting, to the extent feasible with existing equipment, manual handling of all or most of a patient's weight to emergency, life-threatening, or exceptional circumstances; and provision for refusal to perform patient handling tasks believed to involve unacceptable risks of injury to a patient or nurse. Manually lifting patients has been called deplorable, inefficient, dangerous to nurses, and painful and brutal to patients; manual lifting can cause needless suffering and injury to patients, with dangers including pain, bruising, skin tears, abrasions, tube dislodgement, dislocations, fractures, and being dropped by nursing staff during attempts to manually lift. Use of safe, secure, mechanical lift equipment and gentle friction-reducing devices for patient maneuvering tasks could eliminate such needless brutality. Research has proven that manual patient lifting is extremely hazardous to health-care workers, creating substantial risk of low-back injury, whether with one or two patient handlers. Studies on the use of mechanical patient lift equipment, by either nursing staff or lift teams, have proven repeatedly that most nursing staff back injury is preventable, leading to substantial savings to employers on medical and

  5. Advance of Hazardous Operation Robot and its Application in Special Equipment Accident Rescue

    NASA Astrophysics Data System (ADS)

    Zeng, Qin-Da; Zhou, Wei; Zheng, Geng-Feng

    A survey of hazardous operation robot is given out in this article. Firstly, the latest researches such as nuclear industry robot, fire-fighting robot and explosive-handling robot are shown. Secondly, existing key technologies and their shortcomings are summarized, including moving mechanism, control system, perceptive technology and power technology. Thirdly, the trend of hazardous operation robot is predicted according to current situation. Finally, characteristics and hazards of special equipment accident, as well as feasibility of hazardous operation robot in the area of special equipment accident rescue are analyzed.

  6. Impact of shuttle environment on prelaunch handling of nickel-hydrogen batteries

    NASA Technical Reports Server (NTRS)

    Green, R. S.

    1986-01-01

    Deployment of the American Satellite Company 1 spacecraft for the Space Shuttle Discovery in August 1985 set a new milestone in nickel-hydrogen battery technology. This communications satellite is equipped with two 35 Ah nickel-hydrogen batteries and it is the first such satellite launched into orbit via the Space Shuttle. The prelaunch activities, combined with the environmental constraints onboard the Shuttle, led to the development of a new battery handling procedure. An outline of the prelaunch activities, with particular attention to battery charging, is presented.

  7. Microphone Handling Noise: Measurements of Perceptual Threshold and Effects on Audio Quality

    PubMed Central

    Kendrick, Paul; Jackson, Iain R.; Fazenda, Bruno M.; Cox, Trevor J.; Li, Francis F.

    2015-01-01

    A psychoacoustic experiment was carried out to test the effects of microphone handling noise on perceived audio quality. Handling noise is a problem affecting both amateurs using their smartphones and cameras, as well as professionals using separate microphones and digital recorders. The noises used for the tests were measured from a variety of devices, including smartphones, laptops and handheld microphones. The signal features that characterise these noises are analysed and presented. The sounds include various types of transient, impact noises created by tapping or knocking devices, as well as more sustained sounds caused by rubbing. During the perceptual tests, listeners auditioned speech podcasts and were asked to rate the degradation of any unwanted sounds they heard. A representative design test methodology was developed that tried to encourage everyday rather than analytical listening. Signal-to-noise ratio (SNR) of the handling noise events was shown to be the best predictor of quality degradation. Other factors such as noise type or background noise in the listening environment did not significantly affect quality ratings. Podcast, microphone type and reproduction equipment were found to be significant but only to a small extent. A model allowing the prediction of degradation from the SNR is presented. The SNR threshold at which 50% of subjects noticed handling noise was found to be 4.2 ± 0.6 dBA. The results from this work are important for the understanding of our perception of impact sound and resonant noises in recordings, and will inform the future development of an automated predictor of quality for handling noise. PMID:26473498

  8. Differences among nursing homes in outcomes of a safe resident handling program.

    PubMed

    Kurowski, Alicia; Gore, Rebecca; Buchholz, Bryan; Punnett, Laura

    2012-01-01

    A large nursing home corporation implemented a safe resident handling program (SRHP) in 2004-2007. We evaluated its efficacy over a 2-year period by examining differences among 5 centers in program outcomes and potential predictors of those differences. We observed nursing assistants (NAs), recording activities and body postures at 60-second intervals on personal digital assistants at baseline and at 3-month, 12-month, and 24-month follow-ups. The two outcomes computed were change in equipment use during resident handling and change in a physical workload index that estimated spinal loading due to body postures and handled loads. Potential explanatory factors were extracted from post-observation interviews, investigator surveys of the workforce, from administrative data, and employee satisfaction surveys. The facility with the most positive outcome measures was associated with many positive changes in explanatory factors and the facility with the fewest positive outcome measures experienced negative changes in the same factors. These findings suggest greater SRHP benefits where there was lower NA turnover and agency staffing; less time pressure; and better teamwork, staff communication, and supervisory support. © 2012 American Society for Healthcare Risk Management of the American Hospital Association.

  9. Equipment failures and their contribution to industrial incidents and accidents in the manufacturing industry.

    PubMed

    Bourassa, Dominic; Gauthier, François; Abdul-Nour, Georges

    2016-01-01

    Accidental events in manufacturing industries can be caused by many factors, including work methods, lack of training, equipment design, maintenance and reliability. This study is aimed at determining the contribution of failures of commonly used industrial equipment, such as machines, tools and material handling equipment, to the chain of causality of industrial accidents and incidents. Based on a case study which aimed at the analysis of an existing pulp and paper company's accident database, this paper examines the number, type and gravity of the failures involved in these events and their causes. Results from this study show that equipment failures had a major effect on the number and severity of accidents accounted for in the database: 272 out of 773 accidental events were related to equipment failure, where 13 of them had direct human consequences. Failures that contributed directly or indirectly to these events are analyzed.

  10. Machine Learning Classification of Cirrhotic Patients with and without Minimal Hepatic Encephalopathy Based on Regional Homogeneity of Intrinsic Brain Activity.

    PubMed

    Chen, Qiu-Feng; Chen, Hua-Jun; Liu, Jun; Sun, Tao; Shen, Qun-Tai

    2016-01-01

    Machine learning-based approaches play an important role in examining functional magnetic resonance imaging (fMRI) data in a multivariate manner and extracting features predictive of group membership. This study was performed to assess the potential for measuring brain intrinsic activity to identify minimal hepatic encephalopathy (MHE) in cirrhotic patients, using the support vector machine (SVM) method. Resting-state fMRI data were acquired in 16 cirrhotic patients with MHE and 19 cirrhotic patients without MHE. The regional homogeneity (ReHo) method was used to investigate the local synchrony of intrinsic brain activity. Psychometric Hepatic Encephalopathy Score (PHES) was used to define MHE condition. SVM-classifier was then applied using leave-one-out cross-validation, to determine the discriminative ReHo-map for MHE. The discrimination map highlights a set of regions, including the prefrontal cortex, anterior cingulate cortex, anterior insular cortex, inferior parietal lobule, precentral and postcentral gyri, superior and medial temporal cortices, and middle and inferior occipital gyri. The optimized discriminative model showed total accuracy of 82.9% and sensitivity of 81.3%. Our results suggested that a combination of the SVM approach and brain intrinsic activity measurement could be helpful for detection of MHE in cirrhotic patients.

  11. Taking the Heat: Handling the Shuttle's RCC Wing Panels

    NASA Technical Reports Server (NTRS)

    Stegles, Katrine S.

    2008-01-01

    Innovative inspection technology was developed to inspect the Reinforced Carbon-Carbon (RCC) wing panels on the vehicle, thus eliminating need to remove/reinstall all 44 RCC panels for inspections per processing flow. Manually holding inspection tools up to the RCC panels was a 3-person job with high risk of personnel injury and flight hardware damage. To further enhance ergonomics, reduce personnel/flight hardware risks, and improve repeatability, an inspection cart and fixture were constructed to physically secure the instruments for Inspectors during 652 inspection points per flow. The electric lift used to handle RCCs was also utilized to raise the heavy, bulky inspection equipment up to the wing leading edge.

  12. Intelligent Processing Equipment Projects at DLA

    NASA Technical Reports Server (NTRS)

    Obrien, Donald F.

    1992-01-01

    The Defense Logistics Agency is successfully incorporating Intelligent Processing Equipment (IPE) into each of its Manufacturing Technology thrust areas. Several IPE applications are addressed in the manufacturing of two 'soldier support' items: combat rations and military apparel. In combat rations, in-line sensors for food processing are being developed or modified from other industries. In addition, many process controls are being automated to achieve better quality and to gain higher use (soldier) acceptance. IPE applications in military apparel include: in-process quality controls for identification of sewing defects, use of robots in the manufacture of shirt collars, and automated handling of garments for pressing.

  13. Intelligent processing equipment projects at DLA

    NASA Astrophysics Data System (ADS)

    Obrien, Donald F.

    1992-04-01

    The Defense Logistics Agency is successfully incorporating Intelligent Processing Equipment (IPE) into each of its Manufacturing Technology thrust areas. Several IPE applications are addressed in the manufacturing of two 'soldier support' items: combat rations and military apparel. In combat rations, in-line sensors for food processing are being developed or modified from other industries. In addition, many process controls are being automated to achieve better quality and to gain higher use (soldier) acceptance. IPE applications in military apparel include: in-process quality controls for identification of sewing defects, use of robots in the manufacture of shirt collars, and automated handling of garments for pressing.

  14. Identifying minimal hepatic encephalopathy in cirrhotic patients by measuring spontaneous brain activity.

    PubMed

    Chen, Hua-Jun; Zhang, Ling; Jiang, Long-Feng; Chen, Qiu-Feng; Li, Jun; Shi, Hai-Bin

    2016-08-01

    It has been demonstrated that minimal hepatic encephalopathy (MHE) is associated with aberrant regional intrinsic brain activity in cirrhotic patients. However, few studies have investigated whether altered intrinsic brain activity can be used as a biomarker of MHE among cirrhotic patients. In this study, 36 cirrhotic patients (with MHE, n = 16; without MHE [NHE], n = 20) underwent resting-state functional magnetic resonance imaging (fMRI). Spontaneous brain activity was measured by examining the amplitude of low-frequency fluctuations (ALFF) in the fMRI signal. MHE was diagnosed based on the Psychometric Hepatic Encephalopathy Score (PHES). A two-sample t-test was used to determine the regions of interest (ROIs) in which ALFF differed significantly between the two groups; then, ALFF values within ROIs were selected as classification features. A linear discriminative analysis was used to differentiate MHE patients from NHE patients. The leave-one-out cross-validation method was used to estimate the performance of the classifier. The classification analysis was 80.6 % accurate (81.3 % sensitivity and 80.0 % specificity) in terms of distinguishing between the two groups. Six ROIs were identified as the most discriminative features, including the bilateral medial frontal cortex/anterior cingulate cortex, posterior cingulate cortex/precuneus, left precentral and postcentral gyrus, right lingual gyrus, middle frontal gyrus, and inferior/superior parietal lobule. The ALFF values within ROIs were correlated with PHES in cirrhotic patients. Our findings suggest that altered regional brain spontaneous activity is a useful biomarker for MHE detection among cirrhotic patients.

  15. Safety for Compressed Gas and Air Equipment. Module SH-26. Safety and Health.

    ERIC Educational Resources Information Center

    Center for Occupational Research and Development, Inc., Waco, TX.

    This student module on safety for compressed gas and air equipment is one of 50 modules concerned with job safety and health. This module presents technical data about commonly used gases and stresses the procedures necessary for safe handling of compressed gases. Following the introduction, 14 objectives (each keyed to a page in the text) the…

  16. Command and data handling for Atmosphere Explorer satellite

    NASA Technical Reports Server (NTRS)

    Fuldner, W. V.

    1974-01-01

    The command and data-handling subsystem of the Atmosphere Explorer satellite provides the necessary controls for the instrumentation and telemetry, and also controls the satellite attitude and trajectory. The subsystem executes all command information within the spacecraft, either in real time (as received over the S-band command transmission link) or remote from the command site (as required by the orbit operations schedule). Power consumption in the spacecraft is optimized by suitable application and removal of power to various instruments; additional functions include control of magnetic torquers and of the orbit-adjust propulsion subsystem. Telemetry data from instruments and the spacecraft equipment are formatted into a single serial bit stream. Attention is given to command types, command formats, decoder operation, and command processing functions.

  17. Assessment of Minimal HE (with emphasis on computerized psychometric tests)

    PubMed Central

    Kappus, Matthew R; Bajaj, Jasmohan S

    2012-01-01

    Synopsis Minimal hepatic encephalopathy (MHE) is associated with a high risk of development of overt hepatic encephalopathy, impaired quality of life and driving accidents. The detection of MHE requires specialized testing since it cannot by definition, be diagnosed on standard clinical examination. Psychometric (paper-pencil or computerized or a combination) and neuro-physiological techniques are often used to test for MHE. Paper-pencil psychometric batteries like the Psychometric Hepatic Encephalopathy Score (PHES) have been validated in several countries but do not have US normative values. Computerized tests such as the inhibitory control test (ICT), cognitive drug research system and Scan test have proven useful to diagnose MHE and predict outcomes. The specificity and sensitivity of these tests are similar to the recommended gold standards. Neuro-physiological tests such as the EEG and its interpretations, evoked potentials and Critical Flicker Frequency (CFF) also provide useful information. The diagnosis of MHE is an important issue for clinicians and patients alike and the testing strategies depend on the normative data available, patient comfort and local expertise. PMID:22321464

  18. DA Negatively Regulates IGF-I Actions Implicated in Cognitive Function via Interaction of PSD95 and nNOS in Minimal Hepatic Encephalopathy

    PubMed Central

    Ding, Saidan; Zhuge, Weishan; Wang, Xuebao; Yang, Jianjing; Lin, Yuanshao; Wang, Chengde; Hu, Jiangnan; Zhuge, Qichuan

    2017-01-01

    Insulin-like growth factor I (IGF-I) has been positively correlated with cognitive ability. Cognitive decline in minimal hepatic encephalopathy (MHE) was shown to be induced by elevated intracranial dopamine (DA). The beneficial effect of IGF-I signaling in MHE remains unknown. In this study, we found that IGF-I content was reduced in MHE rats and that IGF-I administration mitigated cognitive decline of MHE rats. A protective effect of IGF-I on the DA-induced interaction between postsynaptic density protein 95 (PSD95) and neuronal nitric oxide synthase (nNOS) was found in neurons. Ribosomal S6 protein kinase (RSK) phosphorylated nNOS in response to IGF-I by recruiting extracellular signal-regulated kinase (ERK1/2). In turn, DA inactivated the ERK1/2/RSK pathway and stimulated the PSD95–nNOS interaction by downregulating IGF-I. Inhibition of the interaction between PSD95 and nNOS ameliorated DA-induced memory impairment. As DA induced deficits in the ERK1/2/RSK pathway and the interaction between PSD95 and nNOS in MHE brains, IGF-I administration exerted a protective effect via interruption of the interaction between PSD95 and nNOS. These results suggest that IGF-I antagonizes DA-induced cognitive loss by disrupting PSD95–nNOS interactions in MHE. PMID:28932186

  19. DA Negatively Regulates IGF-I Actions Implicated in Cognitive Function via Interaction of PSD95 and nNOS in Minimal Hepatic Encephalopathy.

    PubMed

    Ding, Saidan; Zhuge, Weishan; Wang, Xuebao; Yang, Jianjing; Lin, Yuanshao; Wang, Chengde; Hu, Jiangnan; Zhuge, Qichuan

    2017-01-01

    Insulin-like growth factor I (IGF-I) has been positively correlated with cognitive ability. Cognitive decline in minimal hepatic encephalopathy (MHE) was shown to be induced by elevated intracranial dopamine (DA). The beneficial effect of IGF-I signaling in MHE remains unknown. In this study, we found that IGF-I content was reduced in MHE rats and that IGF-I administration mitigated cognitive decline of MHE rats. A protective effect of IGF-I on the DA-induced interaction between postsynaptic density protein 95 (PSD95) and neuronal nitric oxide synthase (nNOS) was found in neurons. Ribosomal S6 protein kinase (RSK) phosphorylated nNOS in response to IGF-I by recruiting extracellular signal-regulated kinase (ERK1/2). In turn, DA inactivated the ERK1/2/RSK pathway and stimulated the PSD95-nNOS interaction by downregulating IGF-I. Inhibition of the interaction between PSD95 and nNOS ameliorated DA-induced memory impairment. As DA induced deficits in the ERK1/2/RSK pathway and the interaction between PSD95 and nNOS in MHE brains, IGF-I administration exerted a protective effect via interruption of the interaction between PSD95 and nNOS. These results suggest that IGF-I antagonizes DA-induced cognitive loss by disrupting PSD95-nNOS interactions in MHE.

  20. Construction of a Learning Agent Handling Its Rewards According to Environmental Situations

    NASA Astrophysics Data System (ADS)

    Moriyama, Koichi; Numao, Masayuki

    The authors aim at constructing an agent which learns appropriate actions in a Multi-Agent environment with and without social dilemmas. For this aim, the agent must have nonrationality that makes it give up its own profit when it should do that. Since there are many studies on rational learning that brings more and more profit, it is desirable to utilize them for constructing the agent. Therefore, we use a reward-handling manner that makes internal evaluation from the agent's rewards, and then the agent learns actions by a rational learning method with the internal evaluation. If the agent has only a fixed manner, however, it does not act well in the environment with and without dilemmas. Thus, the authors equip the agent with several reward-handling manners and criteria for selecting an effective one for the environmental situation. In the case of humans, what generates the internal evaluation is usually called emotion. Hence, this study also aims at throwing light on emotional activities of humans from a constructive view. In this paper, we divide a Multi-Agent environment into three situations and construct an agent having the reward-handling manners and the criteria. We observe that the agent acts well in all the three Multi-Agent situations composed of homogeneous agents.

  1. Expanded Occupational Safety and Health Administration 300 log as metric for bariatric patient-handling staff injuries.

    PubMed

    Randall, Stephen B; Pories, Walter J; Pearson, Amy; Drake, Daniel J

    2009-01-01

    Mobilization of morbidly obese patients poses significant physical challenges to healthcare providers. The purpose of this study was to examine the staff injuries associated with the patient handling of the obese, to describe a process for identifying injuries associated with their mobilization, and to report on the need for safer bariatric patient handling. We performed our study at a 761-bed, level 1 trauma center affiliated with a U.S. medical school. The hospital's Occupational Safety and Health Administration (OSHA) 300 log was expanded to the "E-OSHA 300 log" to specifically identify injuries the staff attributed to bariatric patient handling. The 2007 E-OSHA 300 log was analyzed to identify and describe the frequency, severity, and nature of bariatric versus nonbariatric patient handling injuries. The analyses revealed that during 2007, although patients with a body mass index of > or =35 kg/m(2) constituted <10% of our patient population, 29.8% of staff injuries related to patient handling were linked to working with a bariatric patient. Bariatric patient handling accounted for 27.9% of all lost workdays and 37.2% of all restricted workdays associated with patient handling. Registered nurses and nursing assistants accounted for 80% of the injuries related to bariatric patient handling. Turning and repositioning the patient in bed accounted for 31% of the injuries incurred. The E-OSHA 300 log narratives revealed that staff injuries associated with obese and nonobese patient handling were usually performed using biomechanics and not equipment. Manual mobilization of morbidly obese patients increases the risk of caregiver injury. A tracking indicator on the OSHA 300 logs for staff injury linked to a bariatric patient would provide the ability to compare obese and nonobese patient handling injuries. The E-OSHA 300 log provides a method to identify the frequency, severity, and nature of caregiver injury during mobilization of the obese. Understanding the

  2. SITE GENERATED RADIOLOGICAL WASTE HANDLING SYSTEM DESCRIPTION DOCUMENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    S. C. Khamankar

    2000-06-20

    The Site Generated Radiological Waste Handling System handles radioactive waste products that are generated at the geologic repository operations area. The waste is collected, treated if required, packaged for shipment, and shipped to a disposal site. Waste streams include low-level waste (LLW) in solid and liquid forms, as-well-as mixed waste that contains hazardous and radioactive constituents. Liquid LLW is segregated into two streams, non-recyclable and recyclable. The non-recyclable stream may contain detergents or other non-hazardous cleaning agents and is packaged for shipment. The recyclable stream is treated to recycle a large portion of the water while the remaining concentrated wastemore » is packaged for shipment; this greatly reduces the volume of waste requiring disposal. There will be no liquid LLW discharge. Solid LLW consists of wet solids such as ion exchange resins and filter cartridges, as-well-as dry active waste such as tools, protective clothing, and poly bags. Solids will be sorted, volume reduced, and packaged for shipment. The generation of mixed waste at the Monitored Geologic Repository (MGR) is not planned; however, if it does come into existence, it will be collected and packaged for disposal at its point of occurrence, temporarily staged, then shipped to government-approved off-site facilities for disposal. The Site Generated Radiological Waste Handling System has equipment located in both the Waste Treatment Building (WTB) and in the Waste Handling Building (WHB). All types of liquid and solid LLW are processed in the WTB, while wet solid waste from the Pool Water Treatment and Cooling System is packaged where received in the WHB. There is no installed hardware for mixed waste. The Site Generated Radiological Waste Handling System receives waste from locations where water is used for decontamination functions. In most cases the water is piped back to the WTB for processing. The WTB and WHB provide staging areas for storing and

  3. Integrated scheduling of a container handling system with simultaneous loading and discharging operations

    NASA Astrophysics Data System (ADS)

    Li, Chen; Lu, Zhiqiang; Han, Xiaole; Zhang, Yuejun; Wang, Li

    2016-03-01

    The integrated scheduling of container handling systems aims to optimize the coordination and overall utilization of all handling equipment, so as to minimize the makespan of a given set of container tasks. A modified disjunctive graph is proposed and a mixed 0-1 programming model is formulated. A heuristic algorithm is presented, in which the original problem is divided into two subproblems. In the first subproblem, contiguous bay crane operations are applied to obtain a good quay crane schedule. In the second subproblem, proper internal truck and yard crane schedules are generated to match the given quay crane schedule. Furthermore, a genetic algorithm based on the heuristic algorithm is developed to search for better solutions. The computational results show that the proposed algorithm can efficiently find high-quality solutions. They also indicate the effectiveness of simultaneous loading and discharging operations compared with separate ones.

  4. Alumina Handling Dustiness

    NASA Astrophysics Data System (ADS)

    Authier-Martin, Monique

    Dustiness of calcined alumina is a major concern, causing undesirable working conditions and serious alumina losses. These losses occur primarily during unloading and handling or pot loading and crust breaking. The handling side of the problem is first addressed. The Perra pulvimeter constitutes a simple and reproducible tool to quantify handling dustiness and yields results in agreement with plant experience. Attempts are made to correlate dustiness with bulk properties (particle size, attrition index, …) for a large number of diverse aluminas. The characterization of the dust generated with the Perra pulvimeter is most revealing. The effect of the addition of E.S.P. dust is also reported.

  5. Ergonomic material-handling device

    DOEpatents

    Barsnick, Lance E.; Zalk, David M.; Perry, Catherine M.; Biggs, Terry; Tageson, Robert E.

    2004-08-24

    A hand-held ergonomic material-handling device capable of moving heavy objects, such as large waste containers and other large objects requiring mechanical assistance. The ergonomic material-handling device can be used with neutral postures of the back, shoulders, wrists and knees, thereby reducing potential injury to the user. The device involves two key features: 1) gives the user the ability to adjust the height of the handles of the device to ergonomically fit the needs of the user's back, wrists and shoulders; and 2) has a rounded handlebar shape, as well as the size and configuration of the handles which keep the user's wrists in a neutral posture during manipulation of the device.

  6. Development of evaluation models of manpower needs for dismantling the dry conversion process-related equipment in uranium refining and conversion plant (URCP)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sari Izumo; Hideo Usui; Mitsuo Tachibana

    Evaluation models for determining the manpower needs for dismantling various types of equipment in uranium refining and conversion plant (URCP) have been developed. The models are widely applicable to other uranium handling facilities. Additionally, a simplified model was developed for easily and accurately calculating the manpower needs for dismantling dry conversion process-related equipment (DP equipment). It is important to evaluate beforehand project management data such as manpower needs to prepare an optimized decommissioning plan and implement effective dismantling activity. The Japan Atomic Energy Agency (JAEA) has developed the project management data evaluation system for dismantling activities (PRODIA code), which canmore » generate project management data using evaluation models. For preparing an optimized decommissioning plan, these evaluation models should be established based on the type of nuclear facility and actual dismantling data. In URCP, the dry conversion process of reprocessed uranium and others was operated until 1999, and the equipment related to the main process was dismantled from 2008 to 2011. Actual data such as manpower for dismantling were collected during the dismantling activities, and evaluation models were developed using the collected actual data on the basis of equipment classification considering the characteristics of uranium handling facility. (authors)« less

  7. 9 CFR 590.935 - Means of conveyance and equipment used in handling egg products to be maintained in sanitary...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... in handling egg products to be maintained in sanitary condition. 590.935 Section 590.935 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Imports § 590.935 Means of conveyance and...

  8. 9 CFR 590.935 - Means of conveyance and equipment used in handling egg products to be maintained in sanitary...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... in handling egg products to be maintained in sanitary condition. 590.935 Section 590.935 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EGG PRODUCTS INSPECTION INSPECTION OF EGGS AND EGG PRODUCTS (EGG PRODUCTS INSPECTION ACT) Imports § 590.935 Means of conveyance and...

  9. Advanced systems demonstration for utilization of biomass as an energy source. Volume 3: Equipment specifications

    NASA Astrophysics Data System (ADS)

    1980-10-01

    Specifications are given for the shipping, marking, inspection, testing, and start up of equipment to be used in a proposed wood fuel cogeneration system in Maine. Couplings, mechanical drives, electric motors, spare parts, coatings, assembling, and materials handling and packaging are covered. Both OSHA and noise control regulations are included along with the ASME code.

  10. Work-related musculoskeletal risks associated with nurses and nursing assistants handling overweight and obese patients: A literature review.

    PubMed

    Choi, Sang D; Brings, Kathryn

    2015-01-01

    Nurses and nursing assistants are susceptible to work-related musculoskeletal disorders and injuries (WMSDs) due to the increase in overweight and obese patients they are handling on a daily basis. This study aimed to review work-related musculoskeletal hazards and risks associated with handling overweight and obese patients, and summarize the recommended interventions to mitigate musculoskeletal concerns among nurses and nursing assistants. Approximately 350 publications were initially screened and 22 refereed articles were used to synthesize for this study on the bases of inclusion/exclusion relevance and strength of evidence on overweight or obese patient handling. Evidence suggested that the work-related musculoskeletal risks among nurses and nursing assistants included sprains/strains, low back pain, wrist, knee and shoulder injuries. The findings indicated that the WMSD risks increased when nurses and nursing assistants were manually moving or lifting patients, especially when the patients were overweight or obese. The recommended solutions included the lifting/transfer equipment and devices, ergonomic assessments and controls, no-lift policies, and training and education. To alleviate the risk of musculoskeletal disorders and injuries among nurses and nursing assistants handling overweight or obese patients, additional research and development into what safe patient handling interventions suit this growing population needs to be addressed.

  11. Handling small arbovirus vectors safely during biosafety level 3 containment: Culicoides variipennis sonorensis (Diptera:Ceratopogonidae) and exotic bluetongue viruses.

    PubMed

    Hunt, G J; Tabachnick, W J

    1996-05-01

    Equipment and procedures are described for biosafety level 3 (BL-3) containment work with small, zoophilic arthropods. BL-3 classified pathogens always must be manipulated in biological safety cabinets. Procedures, including physical barriers and handling methods, that prevent the escape of potentially virus-infected insects are discussed, and the use of a monitoring system for insect security is explained. The inability to recover escaped minute, flying insects poses a major difference from similar work with larger insects, such as mosquitoes. Methods were developed for the safe and secure handling of Culicoides variipennis sonorensis Wirth & Jones infected with exotic bluetongue viruses during BL-3 containment.

  12. An Exposure Prevention Plan for an Anhydrous Ammonia Handling System

    NASA Technical Reports Server (NTRS)

    Padolewski, Cathy L.; Bower, Amy; Ponikvar, Gary; Mellott, Ken

    1997-01-01

    In July of 1996, the Industrial Hygiene Team of the Environmental Management Office at NASA Lewis Research Center was contacted by the Space Station Program Office to conduct ammonia awareness training for a team of engineers and technicians. The team was tasked with assembling and operating an ammonia handling system for testing of a photovoltaic radiator at the NASA Plum Brook Station Space Power Facility. The ammonia handling system supports a radiator designed to radiate excess heat from a photovoltaic array module used to provide power to the International Space Station. The system would consist of a hazardous materials trailer equipped with an anhydrous ammonia tank, heater, accumulator, chiller, and flow bench. Meetings were held with representatives from the Space Station Program Office, the engineers and Plum Brook safety personnel. Guidance was also provided by representatives from Kennedy Space Center. Determinations were made concerning the locations and types of potential exposures and a plan was developed which included training, personal protective equipment, engineering controls and emergency response. Various organizations including the Plum Brook Safety Committee, the Lewis Environmental Management Office, the Test Readiness Review Board and the Program Office all had requirements that had to be met in order to satisfy themselves that all personnel involved in the operation of the system would be safe. What resulted was a comprehensive plan that provided more than adequate safety measures and succeeded in protecting all personnel from the hazards of the ammonia system. Testing of the photovoltaic radiator was successful and although ammonia leaks were detected and maintenance of the system was ongoing, no one was injured. It was felt that the training and controls in place allowed for a comfort level that did not interfere with the operations.

  13. Mars Sample Handling Protocol Workshop Series: Workshop 4

    NASA Technical Reports Server (NTRS)

    Race Margaret S. (Editor); DeVincenzi, Donald L. (Editor); Rummel, John D. (Editor); Acevedo, Sara E. (Editor)

    2001-01-01

    In preparation for missions to Mars that will involve the return of samples to Earth, it will be necessary to prepare for the receiving, handling, testing, distributing, and archiving of martian materials here on Earth. Previous groups and committees have studied selected aspects of sample return activities, but specific detailed protocols for the handling and testing of returned samples must still be developed. To further refine the requirements for sample hazard testing and to develop the criteria for subsequent release of sample materials from quarantine, the NASA Planetary Protection Officer convened a series of workshops in 2000-2001. The overall objective of the Workshop Series was to produce a Draft Protocol by which returned martian sample materials can be assessed for biological hazards and examined for evidence of life (extant or extinct) while safeguarding the purity of the samples from possible terrestrial contamination. This report also provides a record of the proceedings of Workshop 4, the final Workshop of the Series, which was held in Arlington, Virginia, June 5-7, 2001. During Workshop 4, the sub-groups were provided with a draft of the protocol compiled in May 2001 from the work done at prior Workshops in the Series. Then eight sub-groups were formed to discuss the following assigned topics: Review and Assess the Draft Protocol for Physical/Chemical Testing Review and Assess the Draft Protocol for Life Detection Testing Review and Assess the Draft Protocol for Biohazard Testing Environmental and Health/Monitoring and Safety Issues Requirements of the Draft Protocol for Facilities and Equipment Contingency Planning for Different Outcomes of the Draft Protocol Personnel Management Considerations in Implementation of the Draft Protocol Draft Protocol Implementation Process and Update Concepts This report provides the first complete presentation of the Draft Protocol for Mars Sample Handling to meet planetary protection needs. This Draft Protocol

  14. The effect of laryngoscope handle size on possible endotracheal intubation success in university football, ice hockey, and soccer players.

    PubMed

    Delaney, J Scott; Al-Kashmiri, Ammar; Baylis, Penny-Jane; Aljufaili, Mahmood; Correa, José A

    2012-07-01

    To assess the effectiveness of a standard long-handle laryngoscope and a short-handle laryngoscope on ease of possible intubation in football, ice hockey, and soccer players. Prospective crossover study. University Sport Medicine Clinic. Sixty-two university varsity football (62 males), 45 ice hockey (26 males and 19 females), and 39 soccer players (20 males, 19 females). Athletes were assessed for different airway and physical characteristics. Three different physicians then assessed the use of laryngoscopes of different handle sizes in supine athletes who were wearing protective equipment while in-line cervical spine immobilization was maintained. The ease of passage of a laryngoscope blade into the posterior oropharynx of a supine athlete was assessed using both a standard long-handle and a short-handle laryngoscope. Use of a short-handle laryngoscope was easier for all physicians in all sports as compared with a standard-sized laryngoscope. Passage of a laryngoscope blade into the posterior oropharynx of a supine athlete was easiest in soccer players and most difficult in football and ice hockey players for both sizes of laryngoscope. Interference from chest or shoulder pads was a common cause for difficulty in passing the laryngoscope blade into the posterior oropharynx for football and ice hockey players. In the rare instances that an endotracheal intubation is to be attempted on an unconscious athlete, a short-handle laryngoscope may provide the best chance for successful intubation.

  15. In Patients With Cirrhosis, Driving Simulator Performance Is Associated With Real-life Driving.

    PubMed

    Lauridsen, Mette M; Thacker, Leroy R; White, Melanie B; Unser, Ariel; Sterling, Richard K; Stravitz, Richard T; Matherly, Scott; Puri, Puneet; Sanyal, Arun J; Gavis, Edith A; Luketic, Velimir; Siddiqui, Muhammad S; Heuman, Douglas M; Fuchs, Michael; Bajaj, Jasmohan S

    2016-05-01

    Minimal hepatic encephalopathy (MHE) has been linked to higher real-life rates of automobile crashes and poor performance in driving simulation studies, but the link between driving simulator performance and real-life automobile crashes has not been clearly established. Furthermore, not all patients with MHE are unsafe drivers, but it is unclear how to distinguish them from unsafe drivers. We investigated the link between performance on driving simulators and real-life automobile accidents and traffic violations. We also aimed to identify features of unsafe drivers with cirrhosis and evaluated changes in simulated driving skills and MHE status after 1 year. We performed a study of outpatients with cirrhosis (n = 205; median 55 years old; median model for end-stage liver disease score, 9.5; none with overt hepatic encephalopathy or alcohol or illicit drug use within previous 6 months) seen at the Virginia Commonwealth University and McGuire Veterans Administration Medical Center, from November 2008 through April 2014. All participants were given paper-pencil tests to diagnose MHE (98 had MHE; 48%), and 163 patients completed a standardized driving simulation. Data were collected on traffic violations and automobile accidents from the Virginia Department of Motor Vehicles and from participants' self-assessments when they entered the study, and from 73 participants 1 year later. Participants also completed a questionnaire about alcohol use and cessation patterns. The driving simulator measured crashes, run-time, road center and edge excursions, and illegal turns during navigation; before and after each driving simulation session, patients were asked to rate their overall driving skills. Drivers were classified as safe or unsafe based on crashes and violations reported on official driving records; simulation results were compared with real-life driving records. Multivariable regression analyses of real-life crashes and violations was performed using data on

  16. Students' Strategies for Exception Handling

    ERIC Educational Resources Information Center

    Rashkovits, Rami; Lavy, Ilana

    2011-01-01

    This study discusses and presents various strategies employed by novice programmers concerning exception handling. The main contributions of this paper are as follows: we provide an analysis tool to measure the level of assimilation of exception handling mechanism; we present and analyse strategies to handle exceptions; we present and analyse…

  17. Facility Systems, Ground Support Systems, and Ground Support Equipment General Design Requirements

    NASA Technical Reports Server (NTRS)

    Thaxton, Eric A.

    2014-01-01

    KSC-DE-512-SM establishes overall requirements and best design practices to be used at the John F. Kennedy Space Center (KSC) for the development of ground systems (GS) in support of operations at launch, landing, and retrieval sites. These requirements apply to the design and development of hardware and software for ground support equipment (GSE), ground support systems (GSS), and facility ground support systems (F-GSS) used to support the KSC mission for transportation, receiving, handling, assembly, test, checkout, servicing, and launch of space vehicles and payloads and selected flight hardware items for retrieval. This standards manual supplements NASA-STD-5005 by including KSC-site-specific and local environment requirements. These requirements and practices are optional for equipment used at manufacturing, development, and test sites.

  18. MS Lu installs the TVIS equipment in Zvezda during STS-106

    NASA Image and Video Library

    2000-09-16

    STS106-390-024 (8-20 September 2000) --- Astronaut Edward T. Lu, mission specialist, handles part of the treadmill device on the Service Module for the International Space Station. The crew left this and a large number of other items of hardware and supplies for future inhabitants of the station. Lu and four other astronauts, along with two cosmonauts, are wrapping up a 4.9 million-mile mission in which more than three tons of equipment were delivered to the International outpost.

  19. 46 CFR 111.106-13 - Cargo handling devices or cargo pump rooms handling flammable or combustible cargoes.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... pierced by fixed lights, drive shafts, and pump-engine control rods, provided that the shafts and rods are... 46 Shipping 4 2014-10-01 2014-10-01 false Cargo handling devices or cargo pump rooms handling... OSVs § 111.106-13 Cargo handling devices or cargo pump rooms handling flammable or combustible cargoes...

  20. Activation of neuronal nitric oxide synthase in cerebellum of chronic hepatic encephalopathy rats is associated with up-regulation of NADPH-producing pathway.

    PubMed

    Singh, Santosh; Trigun, Surendra K

    2010-09-01

    Cerebellum-associated functions get affected during mild hepatic encephalopathy (MHE) in patients with chronic liver failure (CLF). Involvement of nitrosative and antioxidant factors in the pathogenesis of chronic hepatic encephalopathy is an evolving concept and needs to be defined in a true CLF animal model. This article describes profiles of NADPH-dependent neuronal nitric oxide synthase (nNOS) and those of glutathione peroxidase and glutathione reductase (GR) vis-a-vis regulation of NADPH-producing pathway in the cerebellum of CLF rats induced by administration of thioacetamide (100 mg kg⁻¹ b.w., i.p.) up to 10 days and confirming MHE on Morris water maze tests. Significant increases in the expression of nNOS protein and nitric oxide (NOx) level coincided with a similar increment in NADPH-diaphorase activity in the cerebellum of CLF rats. Glutathione peroxidase and GR utilize NADPH to regenerate reduced glutathione (GSH) in the cells. Both these enzymes and GSH level were found to be static and thus suggested efficient turnover of GSH in the cerebellum of MHE rats. Relative levels of glucose-6-phosphate dehydrogenase (G6PD) vs. phosphofructokinase 2 (PFK2) determine the rate of pentose phosphate pathway (PPP) responsible to synthesize NADPH. The cerebellum of CLF rats showed overactivation of G6PD with a significant decline in the expression of PFK2 and thus suggested activation of PPP in the cerebellum during MHE. It is concluded that concordant activations of PPP and nNOS in cerebellum of MHE rats could be associated with the implication of NOx in the pathogenesis of MHE.

  1. Subnetwork mining on functional connectivity network for classification of minimal hepatic encephalopathy.

    PubMed

    Zhang, Daoqiang; Tu, Liyang; Zhang, Long-Jiang; Jie, Biao; Lu, Guang-Ming

    2018-06-01

    Hepatic encephalopathy (HE), as a complication of cirrhosis, is a serious brain disease, which may lead to death. Accurate diagnosis of HE and its intermediate stage, i.e., minimal HE (MHE), is very important for possibly early diagnosis and treatment. Brain connectivity network, as a simple representation of brain interaction, has been widely used for the brain disease (e.g., HE and MHE) analysis. However, those studies mainly focus on finding disease-related abnormal connectivity between brain regions, although a large number of studies have indicated that some brain diseases are usually related to local structure of brain connectivity network (i.e., subnetwork), rather than solely on some single brain regions or connectivities. Also, mining such disease-related subnetwork is a challenging task because of the complexity of brain network. To address this problem, we proposed a novel frequent-subnetwork-based method to mine disease-related subnetworks for MHE classification. Specifically, we first mine frequent subnetworks from both groups, i.e., MHE patients and non-HE (NHE) patients, respectively. Then we used the graph-kernel based method to select the most discriminative subnetworks for subsequent classification. We evaluate our proposed method on a MHE dataset with 77 cirrhosis patients, including 38 MHE patients and 39 NHE patients. The results demonstrate that our proposed method can not only obtain the improved classification performance in comparison with state-of-the-art network-based methods, but also identify disease-related subnetworks which can help us better understand the pathology of the brain diseases.

  2. Nurses' use of hazardous drug-handling precautions and awareness of national safety guidelines.

    PubMed

    Polovich, Martha; Martin, Susan

    2011-11-01

    To determine patterns of personal protective equipment (PPE) used by oncology nurses while handling hazardous drugs (HDs) and to assess knowledge of the 2004 National Institute for Occupational Safety and Health (NIOSH) Alert and its effect on precaution use. Descriptive, correlational. The Oncology Nursing Society 31st Annual Congress in Boston, MA, in 2006. 330 nurses who prepared and/or administered chemotherapy. Nurses described HD safe-handling precaution use by self-report survey. The availability and use of biologic safety cabinets and PPE. Respondents were well educated (57% had a bachelor's degree or more), experienced (X = 19, SD = 10.2 years in nursing and X = 12, SD = 7.9 years in oncology), and certified (70%; majority OCN®). Forty-seven percent of respondents were aware of the NIOSH Alert. Thirty-five percent of all participants and 93% of nurses in private practice settings reported preparing chemotherapy. Glove use (95%-100%) was higher than that reported in earlier studies, and gown use for drug preparation (65%), drug administration (50%), and handling excretions (23%) have remained unchanged. Double-gloving was rare (11%-18%). Nurses in private practices were less likely to have chemotherapy-designated PPE available, use PPE, and use spill kits for HD spills. Nurses have adopted glove use for HD handling; however, gown use remains comparatively low. Chemotherapy-designated PPE is not always provided by employers. Nurses lack awareness of current safety guidelines. Nurses must know about the risks of HD exposure and ways to reduce exposure. Employers must provide appropriate PPE and encourage its use. Alternative methods of disseminating safety recommendations are needed.

  3. Development of a System to Validate Group 3 Facsimile Equipment. Phase I.

    DTIC Science & Technology

    1981-07-01

    such as modem , equalizer, line connection etc.) in hardware is. unavoidable. 3. Unless computer and test equipment are co-resident, hardware will be...network simulator. Most of this hardware/firmware has been developed for data transmission in general (v.27 ter/V.29 modems )or specifically for Group 3...system with the facsimile unit under test. 2. V.27 ter/V.29 modems - to handle facsimile data at the various data rate. 3. Modem control and switching

  4. Helicopter Handling Qualities

    NASA Technical Reports Server (NTRS)

    1982-01-01

    Helicopters are used by the military and civilian communities for a variety of tasks and must be capable of operating in poor weather conditions and at night. Accompanying extended helicopter operations is a significant increase in pilot workload and a need for better handling qualities. An overview of the status and problems in the development and specification of helicopter handling-qualities criteria is presented. Topics for future research efforts by government and industry are highlighted.

  5. Modular magazine for suitable handling of microparts in industry

    NASA Astrophysics Data System (ADS)

    Grimme, Ralf; Schmutz, Wolfgang; Schlenker, Dirk; Schuenemann, Matthias; Stock, Achim; Schaefer, Wolfgang

    1998-01-01

    Microassembly and microadjustment techniques are key technologies in the industrial production of hybrid microelectromechanical systems. One focal point in current microproduction research and engineering is the design and development of high-precision microassembly and microadjustment equipment capable of operating within the framework of flexible automated industrial production. As well as these developments, suitable microassembly tools for industrial use also need to be equipped with interfaces for the supply and delivery of microcomponents. The microassembly process necessitates the supply of microparts in a geometrically defined manner. In order to reduce processing steps and production costs, there is a demand for magazines capable of providing free accessibility to the fixed microcomponents. Commonly used at present are feeding techniques, which originate from the field of semiconductor production. However none of these techniques fully meets the requirements of industrial microassembly technology. A novel modular magazine set, developed and tested in a joint project, is presented here. The magazines are able to hold microcomponents during cleaning, inspection and assembly without nay additional handling steps. The modularity of their design allows for maximum technical flexibility. The modular magazine fits into currently practiced SEMI standards. The design and concept of the magazine enables industrial manufacturers to promote a cost-efficient and flexible precision assembly of microelectromechanical systems.

  6. Probiotics are helpful in hepatic encephalopathy: a meta-analysis of randomized trials.

    PubMed

    Saab, Sammy; Suraweera, Duminda; Au, Jennifer; Saab, Elena G; Alper, Tori S; Tong, Myron J

    2016-07-01

    Hepatic encephalopathy (HE) is a major complication of cirrhosis and is associated with decreased survival and increased health care utilization. The aim of this study was to evaluate the efficacy of probiotics in the management minimal hepatic encephalopathy HE (MHE) and overt HE (OHE) in comparison to no treatment/placebo and lactulose. The main outcomes measured were mortality, improvement in MHE, progression to OHE in patients with MHE and hospitalization. We calculated odds ratios (OR) with 95% confidence intervals (CI). Study heterogeneity was assessed using the I(2) statistic. Fourteen studies totalling 1152 patients were included in the analysis. The use of probiotics had no impact on the overall mortality when compared to either lactulose (OR: 1.07, 95% CI: 0.47-2.44, P = 0.88) or no treatment/placebo (OR: 0.69, 95% CI: 0.42-1.14, P = 0.15). When probiotics was compared to no treatment/placebo, it was associated with a significant improvement in MHE (OR: 3.91, 95% CI: 2.25-6.80, P < 0.00001), decreased hospitalization rates (OR: 0.53, 95% CI: 0.33-0.86, P = 0.01) and decreased progression to overt hepatic encephalopathy (OR: 0.40, 95% CI: 0.26-0.60, P < 0.0001). However when compared to lactulose, probiotics did not show a significant difference in improvement of MHE (OR: 0.81, 95% CI: 0.52-1.27, P = 0.35), hospitalization rates (OR: 1.02, 95% CI: 0.52-1.99, P = 0.96) or progression to overt hepatic encephalopathy (OR: 1.24, 95% CI 0.73-2.10, P = 0.42). Overall the use of probiotics was more effective in decreasing hospitalization rates, improving MHE and preventing progression to OHE in patients with underlying MHE than placebo, but similar to that seen with lactulose. The use of probiotics did not affect mortality rates. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  7. 7 CFR 1210.307 - Handle.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE WATERMELON RESEARCH AND PROMOTION PLAN Watermelon Research and Promotion Plan Definitions § 1210.307 Handle. Handle means to grade, pack...

  8. 7 CFR 1210.307 - Handle.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE WATERMELON RESEARCH AND PROMOTION PLAN Watermelon Research and Promotion Plan Definitions § 1210.307 Handle. Handle means to grade, pack...

  9. 7 CFR 1210.307 - Handle.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE WATERMELON RESEARCH AND PROMOTION PLAN Watermelon Research and Promotion Plan Definitions § 1210.307 Handle. Handle means to grade, pack...

  10. 7 CFR 1210.307 - Handle.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE WATERMELON RESEARCH AND PROMOTION PLAN Watermelon Research and Promotion Plan Definitions § 1210.307 Handle. Handle means to grade, pack...

  11. Grain Handling and Storage.

    ERIC Educational Resources Information Center

    Harris, Troy G.; Minor, John

    This text for a secondary- or postecondary-level course in grain handling and storage contains ten chapters. Chapter titles are (1) Introduction to Grain Handling and Storage, (2) Elevator Safety, (3) Grain Grading and Seed Identification, (4) Moisture Control, (5) Insect and Rodent Control, (6) Grain Inventory Control, (7) Elevator Maintenance,…

  12. Application of the WHO keys of safer food to improve food handling practices of food vendors in a poor resource community in Ghana.

    PubMed

    Donkor, Eric S; Kayang, Boniface B; Quaye, Jonathan; Akyeh, Moses L

    2009-11-01

    Data was collected from food vendors in a poor resource community in Ghana, which showed that the vendors constituted an important source of oro-faecal transmission. Following this, the WHO five keys of safer food were utilized in an evidence based training programme for the vendors to improve their food handling practices. Impact assessment of the food safety training showed that 67.6% of the vendors had acquired some knowledge from the workshop and were putting it into practice. Lack of food safety equipment was a major hinderance to behavioral change among the vendors as far food handling practices are concerned.

  13. Cleaning and sterilisation of infant feeding equipment: a systematic review.

    PubMed

    Renfrew, Mary J; McLoughlin, Marie; McFadden, Alison

    2008-11-01

    To assess the clinical and cost-effectiveness of different methods of cleaning and sterilisation of infant feeding equipment used in the home. Systematic review of studies from developed countries on the effectiveness of methods of cleaning and sterilisation of infant feeding equipment used in the home. A brief telephone survey of UK-based manufacturers of infant feeding equipment and formula to ascertain the evidence base used for their recommendations, and a comparison of current relevant guidelines in developed countries, informed the work. National guidelines from six countries demonstrated variation and lack of evidence to support current guidance. Manufacturers did not report evidence of effectiveness to support their recommendations. Nine studies were identified; eight conducted between 1962 and 1985 and one in 1997. All had methodological weaknesses. Hand-washing was identified as fundamentally important. Health professionals were reported as not providing appropriate education on the importance and methods of cleaning and sterilisation. Mothers of subsequent babies and women from lower socio-economic groups were less likely to follow recommended procedures. There is a lack of good-quality evidence on effective ways of cleaning and sterilising infant feeding equipment in the home. The evidence base does not answer the question about which of the methods in common use is most effective or most likely to be used by parents. Hand-washing before handling feeding equipment remains important. Further research on the range of methods used in the home environment, including assessment of the views of parents and carers, is required.

  14. The Vermicelli Handling Test: A Simple Quantitative Measure of Dexterous Forepaw Function in Rats

    PubMed Central

    Allred, Rachel P.; Adkins, DeAnna L.; Woodlee, Martin T.; Husbands, Lincoln C.; Maldonado, Mónica A.; Kane, Jacqueline R.; Schallert, Timothy; Jones, Theresa A.

    2008-01-01

    Loss of function in the hands occurs with many brain disorders, but there are few measures of skillful forepaw use in rats available to model these impairments that are both sensitive and simple to administer. Whishaw and Coles (1996) previously described the dexterous manner in which rats manipulate food items with their paws, including thin pieces of pasta. We set out to develop a measure of this food handling behavior that would be quantitative, easy to administer, sensitive to the effects of damage to sensory and motor systems of the CNS and useful for identifying the side of lateralized impairments. When rats handle 7 cm lengths of vermicelli, they manipulate the pasta by repeatedly adjusting the forepaw hold on the pasta piece. As operationally defined, these adjustments can be easily identified and counted by an experimenter without specialized equipment. After unilateral sensorimotor cortex (SMC) lesions, transient middle cerebral artery occlusion (MCAO) and striatal dopamine depleting (6-hydroxydopamine, 6-OHDA) lesions in adult rats, there were enduring reductions in adjustments made with the contralateral forepaw. Additional pasta handling characteristics distinguished between the lesion types. MCAO and 6-OHDA lesions increased the frequency of several identified atypical handling patterns. Severe dopamine depletion increased eating time and adjustments made with the ipsilateral forepaw. However, contralateral forepaw adjustment number most sensitively detected enduring impairments across lesion types. Because of its ease of administration and sensitivity to lateralized impairments in skilled forepaw use, this measure may be useful in rat models of upper extremity impairment. PMID:18325597

  15. 7 CFR 905.9 - Handle or ship.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Handle or ship. 905.9 Section 905.9 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... TANGELOS GROWN IN FLORIDA Order Regulating Handling Definitions § 905.9 Handle or ship. Handle or ship...

  16. 7 CFR 948.8 - Handle or ship.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Handle or ship. 948.8 Section 948.8 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Order Regulating Handling Definitions § 948.8 Handle or ship. Handle or ship means to transport, sell...

  17. 7 CFR 905.9 - Handle or ship.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Handle or ship. 905.9 Section 905.9 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... TANGELOS GROWN IN FLORIDA Order Regulating Handling Definitions § 905.9 Handle or ship. Handle or ship...

  18. 7 CFR 905.9 - Handle or ship.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Handle or ship. 905.9 Section 905.9 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... TANGELOS GROWN IN FLORIDA Order Regulating Handling Definitions § 905.9 Handle or ship. Handle or ship...

  19. 7 CFR 948.8 - Handle or ship.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Handle or ship. 948.8 Section 948.8 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Order Regulating Handling Definitions § 948.8 Handle or ship. Handle or ship means to transport, sell...

  20. 7 CFR 905.9 - Handle or ship.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Handle or ship. 905.9 Section 905.9 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... TANGELOS GROWN IN FLORIDA Order Regulating Handling Definitions § 905.9 Handle or ship. Handle or ship...

  1. 7 CFR 948.8 - Handle or ship.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Handle or ship. 948.8 Section 948.8 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... Order Regulating Handling Definitions § 948.8 Handle or ship. Handle or ship means to transport, sell...

  2. 7 CFR 948.8 - Handle or ship.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Handle or ship. 948.8 Section 948.8 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Order Regulating Handling Definitions § 948.8 Handle or ship. Handle or ship means to transport, sell...

  3. FUEL HANDLING MECHANISM

    DOEpatents

    Koch, L.J.; Hutter, E.

    1960-02-01

    A remotely operable handling device specifically adapted for the handling of vertically disposed fuel rods in a nuclear reactor was developed. The device consists essentially of an elongated tubular member having a gripping device at the lower end of the pivoted jaw type adapted to grip an enlarged head on the upper end of the workpiece. The device includes a sensing element which engages the enlarged head and is displaced to remotely indicate when the workpiece is in the proper position to be engaged by the jaws.

  4. 7 CFR 58.443 - Whey handling.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Whey handling. 58.443 Section 58.443 Agriculture... Procedures § 58.443 Whey handling. (a) Adequate sanitary facilities shall be provided for the handling of whey. If outside, necessary precautions shall be taken to minimize flies, insects and development of...

  5. 7 CFR 945.9 - Ship or handle.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Ship or handle. 945.9 Section 945.9 Agriculture... DESIGNATED COUNTIES IN IDAHO, AND MALHEUR COUNTY, OREGON Order Regulating Handling Definitions § 945.9 Ship or handle. Ship or handle means to pack, sell, consign, transport or in any other way to place...

  6. 7 CFR 927.8 - Ship or handle.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Ship or handle. 927.8 Section 927.8 Agriculture... Order Regulating Handling Definitions § 927.8 Ship or handle. Ship or handle means to sell, deliver, consign, transport or ship pears within the production area or between the production area and any point...

  7. 7 CFR 927.8 - Ship or handle.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Ship or handle. 927.8 Section 927.8 Agriculture... Order Regulating Handling Definitions § 927.8 Ship or handle. Ship or handle means to sell, deliver, consign, transport or ship pears within the production area or between the production area and any point...

  8. 7 CFR 945.9 - Ship or handle.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Ship or handle. 945.9 Section 945.9 Agriculture... DESIGNATED COUNTIES IN IDAHO, AND MALHEUR COUNTY, OREGON Order Regulating Handling Definitions § 945.9 Ship or handle. Ship or handle means to pack, sell, consign, transport or in any other way to place...

  9. 7 CFR 927.8 - Ship or handle.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Ship or handle. 927.8 Section 927.8 Agriculture... Order Regulating Handling Definitions § 927.8 Ship or handle. Ship or handle means to sell, deliver, consign, transport or ship pears within the production area or between the production area and any point...

  10. 7 CFR 945.9 - Ship or handle.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Ship or handle. 945.9 Section 945.9 Agriculture... DESIGNATED COUNTIES IN IDAHO, AND MALHEUR COUNTY, OREGON Order Regulating Handling Definitions § 945.9 Ship or handle. Ship or handle means to pack, sell, consign, transport or in any other way to place...

  11. 7 CFR 927.8 - Ship or handle.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Ship or handle. 927.8 Section 927.8 Agriculture... Order Regulating Handling Definitions § 927.8 Ship or handle. Ship or handle means to sell, deliver, consign, transport or ship pears within the production area or between the production area and any point...

  12. 7 CFR 927.8 - Ship or handle.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Ship or handle. 927.8 Section 927.8 Agriculture... Order Regulating Handling Definitions § 927.8 Ship or handle. Ship or handle means to sell, deliver, consign, transport or ship pears within the production area or between the production area and any point...

  13. Factors affecting food handling Practices among food handlers of Dangila town food and drink establishments, North West Ethiopia

    PubMed Central

    2014-01-01

    Background Food borne diseases are major health problems in developed and developing countries including Ethiopia. The problem is more noticeable in developing countries due to prevailing poor food handling and sanitation practices, inadequate food safety laws, weak regulatory systems, lack of financial resources to invest on safer equipments, and lack of education for food handlers. Methods The objective of this study was to assess food handling practice and associated factors among food handlers working in food and drinking establishments of Dangila town, North West Ethiopia. Cross-sectional quantitative study design was conducted among 406 food handlers working in 105 food and drink establishments from July to August 2013 in Dangila town. Data were collected using face to face interview with pretested structured questionnaire and physical observation. Result The mean age of the respondents was 22.7 ± 4.2 years of which 62.8% of the food handlers were females. Two hundred thirteen (52.5%) of food handlers had good food handling practices. Marital status (AOR = 7.52, 95% CI, 1.45-38.97), monthly income (AOR = 0.395, 95% CI, 0.25-0.62), knowledge about food handling (AOR = 1.69, 95% CI, 1.05-2.73), existence of shower facility (AOR = 1.89, 95% CI, 1.12-3.21) and separate dressing room (AOR = 1.97, 95% CI, 1.11-3.49) were found to be significantly associated with good food handling Practices. Conclusion Above half of food handlers had good food handling practices. Marital status, monthly income, knowledge status, existence of shower facility, existence of separate dressing room and presence of insect and rodent were factors associated with food handling Practices. PMID:24908104

  14. Manual handling risks associated with the care, treatment and transportation of bariatric patients and clients in Australia.

    PubMed

    Cowley, Stephen P; Leggett, Susan

    2010-06-01

    To gain an understanding of the factors that affect the risks and the adoption of risk control measures during the care of bariatric patients, focus groups were conducted in rural and metropolitan locations in Australia. It was found that the manual handling injury risk to carers is influenced by the design of the environments within which patient movement is undertaken; the limited range of handling equipment available for use with bariatric patients; and the efficacy of organizational procedures and training. Adoption of risk controls is hampered by the absence of a standard definition of the term 'bariatric' and limitations in the use of weight and body mass index in definitions. There are gaps in information flow during the bariatric patient journey through the health-care system and a lack of knowledge about how to safely manage the unique needs of bariatric patients.

  15. Reviews Equipment: Data logger Book: Imagined Worlds Equipment: Mini data loggers Equipment: PICAXE-18M2 data logger Books: Engineering: A Very Short Introduction and To Engineer Is Human Book: Soap, Science, & Flat-Screen TVs Equipment: uLog and SensorLab Web Watch

    NASA Astrophysics Data System (ADS)

    2012-07-01

    WE RECOMMEND Data logger Fourier NOVA LINK: data logging and analysis To Engineer is Human Engineering: essays and insights Soap, Science, & Flat-Screen TVs People, politics, business and science overlap uLog sensors and sensor adapter A new addition to the LogIT range offers simplicity and ease of use WORTH A LOOK Imagined Worlds Socio-scientific predictions for the future Mini light data logger and mini temperature data logger Small-scale equipment for schools SensorLab Plus LogIT's supporting software, with extra features HANDLE WITH CARE CAXE110P PICAXE-18M2 data logger Data logger 'on view' but disappoints Engineering: A Very Short Introduction A broad-brush treatment fails to satisfy WEB WATCH Two very different websites for students: advanced physics questions answered and a more general BBC science resource

  16. Improving the inhibitory control task to detect minimal hepatic encephalopathy.

    PubMed

    Amodio, Piero; Ridola, Lorenzo; Schiff, Sami; Montagnese, Sara; Pasquale, Chiara; Nardelli, Silvia; Pentassuglio, Ilaria; Trezza, Maria; Marzano, Chiara; Flaiban, Cristiana; Angeli, Paolo; Cona, Giorgia; Bisiacchi, Patrizia; Gatta, Angelo; Riggio, Oliviero

    2010-08-01

    Quantification of the number of noninhibited responses (lures) in the inhibitory control task (ICT) has been proposed for the diagnosis of minimal hepatic encephalopathy (MHE). We assessed the efficacy of ICT compared with recommended diagnostic standards. We studied patients with cirrhosis and healthy individuals (controls) who underwent the ICT at 2 centers (center A: n=51 patients and 41 controls, center B: n=24 patients and 14 controls). Subjects were evaluated for MHE by psychometric hepatic encephalopathy score (PHES). Patients from center B also were assessed for MHE by critical flicker frequency and spectral electroencephalogram analyses. Patients with cirrhosis had higher ICT lures (23.2+/-12.8 vs 12.9+/-5.8, respectively, P<.01) and lower ICT target accuracy (0.88+/-0.17 vs 0.96+/-0.03, respectively, P<.01) compared with controls. However, lures were comparable (25.2+/-12.5 vs 21.4+/-13.9, respectively, P=.32) among patients with/without altered PHES (center A). There was a reverse, U-shaped relationship between ICT lure and target accuracy; a variable adjusting lures was devised based on target accuracy (weighted lures at center B). This variable differed between patients with and without MHE. The variable weighted lures was then validated from data collected at center A by receiver operator characteristic curve analysis; it discriminated between patients with and without PHES alterations (area under the curve=0.71+/-0.07). However, target accuracy alone was as effective as a stand-alone variable (area under the curve=0.81+/-0.06). The ICT is not useful for the diagnosis of MHE, unless adjusted by target accuracy. Testing inhibition (lures) does not seem to be superior to testing attention (target accuracy) for the detection of MHE. Copyright (c) 2010 AGA Institute. Published by Elsevier Inc. All rights reserved.

  17. MINIMAL HEPATIC ENCEPHALOPATHY IS ASSOCIATED WITH MOTOR VEHICLE CRASHES: THE REALITY BEYOND THE DRIVING TEST

    PubMed Central

    Bajaj, Jasmohan S; Saeian, Kia; Schubert, Christine M; Hafeezullah, Muhammad; Franco, Jose; Varma, Rajiv R; Gibson, Douglas P; Hoffmann, Raymond G; Stravitz, R Todd; Heuman, Douglas M; Sterling, Richard K; Shiffman, Mitchell; Topaz, Allyne; Boyett, Sherry; Bell, Debulon; Sanyal, Arun J

    2009-01-01

    Patients with minimal hepatic encephalopathy (MHE) have impaired driving skills, but association of MHE with motor vehicle crashes is unclear. Standard psychometric tests (SPT) or inhibitory control test (ICT) can be used to diagnose MHE. The aim was to determine the association of MHE with crashes and traffic violations over the preceding year and on 1-year follow-up. Cirrhotics were diagnosed with MHE by ICT (MHEICT) and SPT (MHESPT). Self and department-of-transportation (DOT)-reports were used to determine crashes and violations over the preceding year. Agreement between self and DOT-reports was analyzed. Patients then underwent 1 year follow-up for crash/violation occurrence. Crashes in those with/without MHEICT and MHESPT were compared. 167 cirrhotics had DOT-reports, of which 120 also had self-reports. A significantly higher proportion of MHEICT cirrhotics experienced crashes in the preceding year compared to those without MHE by self-report (17% vs. 0%, p=0.0004) and DOT-reports (17% vs. 3%, p=0.004, relative risk:5.77). SPT did not differentiate between those with/without crashes. A significantly higher proportion of patients with crashes had MHEICT compared to MHESPT, both self-reported (100% vs. 50%, p=0.03) and DOT-reported (89% vs. 44%, p=0.01). There was excellent agreement between self and DOT-reports for crashes and violations (Kappa 0.90 and 0.80). 109 patients were followed prospectively. MHEICT patients had a significantly higher future crashes/violations compared to those without (22% vs. 7%, p=0.03) but MHESPT did not. MHEICT (Odds ratio:4.51) and prior year crash/violation (Odds ratio:2.96) were significantly associated with future crash/violation occurrence. PMID:19670416

  18. Validation of a Paper and Pencil Test Battery for the Diagnosis of Minimal Hepatic Encephalopathy in Korea.

    PubMed

    Jeong, Jae Yoon; Jun, Dae Won; Bai, Daiseg; Kim, Ji Yean; Sohn, Joo Hyun; Ahn, Sang Bong; Kim, Sang Gyune; Kim, Tae Yeob; Kim, Hyoung Su; Jeong, Soung Won; Cho, Yong Kyun; Song, Do Seon; Kim, Hee Yeon; Jung, Young Kul; Yoon, Eileen L

    2017-09-01

    The aim of this study was to validate a new paper and pencil test battery to diagnose minimal hepatic encephalopathy (MHE) in Korea. A new paper and pencil test battery was composed of number connection test-A (NCT-A), number connection test-B (NCT-B), digit span test (DST), and symbol digit modality test (SDMT). The norm of the new test was based on 315 healthy individuals between the ages of 20 and 70 years old. Another 63 healthy subjects (n = 31) and cirrhosis patients (n = 32) were included as a validation cohort. All participants completed the new paper and pencil test, a critical flicker frequency (CFF) test and computerized cognitive function test (visual continuous performance test [CPT]). The scores on the NCT-A and NCT-B increased but those of DST and SDMT decreased according to age. Twelve of the cirrhotic patients (37.5%) were diagnosed with MHE based on the new paper and pencil test battery. The total score of the paper and pencil test battery showed good positive correlation with the CFF (r = 0.551, P < 0.001) and computerized cognitive function test. Also, this score was lower in patients with MHE compared to those without MHE (P < 0.001). Scores on the CFF (32.0 vs. 28.7 Hz, P = 0.028) and the computer base cognitive test decreased significantly in patients with MHE compared to those without MHE. Test-retest reliability was comparable. In conclusion, the new paper and pencil test battery including NCT-A, NCT-B, DST, and SDMT showed good correlation with neuropsychological tests. This new paper and pencil test battery could help to discriminate patients with impaired cognitive function in cirrhosis (registered at Clinical Research Information Service [CRIS], https://cris.nih.go.kr/cris, KCT0000955). © 2017 The Korean Academy of Medical Sciences.

  19. Assessing the brain through the eye: New ways to explore hepatic encephalopathy.

    PubMed

    Arias, Natalia; Méndez, Marta; Alcalde, Ignacio; Íñigo-Portugués, Almudena; Merayo-Lloves, Jesús; Arias, Jaime; Arias, Jorge L

    2017-05-01

    Minimal hepatic encephalopathy (mHE) has been shown to affect daily functioning, quality of life, driving and overall mortality. However, little is known about treating or diagnosing early impairments in mHE. We studied one of its precipitating factors, portal hypertension which is driving the inflammatory process behind mHE. The purpose was to describe an indirect diagnostic method able to detect the pathology at early stages based on the study of the vascularization and mast cells conjunctival hyperplasia as secondary inflammatory response associated to portal hypertension. Finally, we correlated the presence of histological changes in the eye in mHE with deficits in behavioral task acquisition. Rats were trained on a stimulus-response task and a spatial working memory task using the Morris water maze. Two groups of animals were used: a SHAM (sham-operated) group (n=10) and a portal hypertension (HT) group (n=10). The triple portal vein ligation method was used to create an animal model of mHE. Latencies to reach the platform, number of glial fibrillary acidic protein-immunoreactive astrocytes (GFAP-IR), mast cell expression and presence/absence of blood and lymphatic vessels were examined. There were differences in stimulus-response behavioral performance, with a deficit in the acquisition in the HT group. However, no differences between groups were found on the spatial working memory task. At the same time, differences between groups were found in the GFAP-IR density, which was lower in the HT group, and in the number of mast cells and the presence of vessels, which were higher in the HT group. In this study, we provide the first preliminary insight into the validity of exploring the eye as a possible tool to assess the diagnosis of mHE conditions. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Handling an Asthma Flare-Up

    MedlinePlus

    ... Videos for Educators Search English Español Handling an Asthma Flare-Up KidsHealth / For Kids / Handling an Asthma ... español Cómo controlar las crisis asmáticas What's an Asthma Flare-Up? If you have asthma , you probably ...

  1. 7 CFR 1205.312 - Handle.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE COTTON RESEARCH AND PROMOTION Cotton Research and Promotion Order Definitions § 1205.312 Handle. Handle means to harvest, gin, warehouse, compress, purchase, market, transport, or otherwise acquire ownership or control of cotton. [31 FR 16758...

  2. 7 CFR 983.14 - Handle.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE PISTACHIOS GROWN IN CALIFORNIA, ARIZONA, AND NEW MEXICO Definitions § 983.14 Handle. Handle means to engage in: (a) Receiving pistachios; (b) Hulling and drying pistachios; (c) Further preparing pistachios by sorting, sizing, shelling, roasting...

  3. 7 CFR 1219.11 - Handle.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.11 Handle. Handle means to pack, process, transport, purchase, or in any other way to place or cause Hass avocados...

  4. 7 CFR 1219.11 - Handle.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.11 Handle. Handle means to pack, process, transport, purchase, or in any other way to place or cause Hass avocados...

  5. 7 CFR 1219.11 - Handle.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.11 Handle. Handle means to pack, process, transport, purchase, or in any other way to place or cause Hass avocados...

  6. 7 CFR 1219.11 - Handle.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE HASS AVOCADO PROMOTION, RESEARCH, AND INFORMATION Hass Avocado Promotion, Research, and Information Order Definitions § 1219.11 Handle. Handle means to pack, process, transport, purchase, or in any other way to place or cause Hass avocados...

  7. Magnetospheric equilibrium configurations and slow adiabatic convection

    NASA Technical Reports Server (NTRS)

    Voigt, Gerd-Hannes

    1986-01-01

    This review paper demonstrates how the magnetohydrostatic equilibrium (MHE) theory can be used to describe the large-scale magnetic field configuration of the magnetosphere and its time evolution under the influence of magnetospheric convection. The equilibrium problem is reviewed, and levels of B-field modelling are examined for vacuum models, quasi-static equilibrium models, and MHD models. Results from two-dimensional MHE theory as they apply to the Grad-Shafranov equation, linear equilibria, the asymptotic theory, magnetospheric convection and the substorm mechanism, and plasma anisotropies are addressed. Results from three-dimensional MHE theory are considered as they apply to an intermediate analytical magnetospheric model, magnetotail configurations, and magnetopause boundary conditions and the influence of the IMF.

  8. 7 CFR 1216.12 - Handle.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PEANUT PROMOTION, RESEARCH, AND INFORMATION ORDER Peanut Promotion, Research, and Information Order Definitions § 1216.12 Handle. Handle means... peanuts and in the shipment (except as a common or contract carrier of peanuts owned by another) or sale...

  9. 7 CFR 1216.12 - Handle.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE PEANUT PROMOTION, RESEARCH, AND INFORMATION ORDER Peanut Promotion, Research, and Information Order Definitions § 1216.12 Handle. Handle means... peanuts and in the shipment (except as a common or contract carrier of peanuts owned by another) or sale...

  10. 7 CFR 926.9 - Handle.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements and... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.9 Handle. Handle... cranberries or processed cranberries up to, but not including, the retail level. Effective Date Note: At 71 FR...

  11. The natural angle between the hand and handle and the effect of handle orientation on wrist radial/ulnar deviation during maximal push exertions.

    PubMed

    Young, Justin G; Lin, Jia-Hua; Chang, Chien-Chi; McGorry, Raymond W

    2013-01-01

    The purpose of this experiment was to quantify the natural angle between the hand and a handle, and to investigate three design factors: handle rotation, handle tilt and between-handle width on the natural angle as well as resultant wrist radial/ulnar deviation ('RUD') for pushing tasks. Photographs taken of the right upper limb of 31 participants (14 women and 17 men) performing maximal seated push exertions on different handles were analysed. Natural hand/handle angle and RUD were assessed. It was found that all of the three design factors significantly affected natural handle angle and wrist RUD, but participant gender did not. The natural angle between the hand and the cylindrical handle was 65 ± 7°. Wrist deviation was reduced for handles that were rotated 0° (horizontal) and at the narrow width (31 cm). Handles that were tilted forward 15° reduced radial deviation consistently (12-13°) across handle conditions. Manual materials handling (MMH) tasks involving pushing have been related to increased risk of musculoskeletal injury. This study shows that handle orientation influences hand and wrist posture during pushing, and suggests that the design of push handles on carts and other MMH aids can be improved by adjusting their orientation to fit the natural interface between the hand and handle.

  12. 7 CFR 1207.307 - Handle.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.307 Handle. Handle means to grade, pack, process, sell, transport, purchase, or in any other way to place potatoes or cause potatoes to be placed in the...

  13. 7 CFR 1219.11 - Handle.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Handle. 1219.11 Section 1219.11 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS.... Handle means to pack, process, transport, purchase, or in any other way to place or cause Hass avocados...

  14. 21 CFR 820.140 - Handling.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Handling. 820.140 Section 820.140 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES..., contamination, or other adverse effects to product do not occur during handling. ...

  15. 9 CFR 3.118 - Handling.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Handling. 3.118 Section 3.118 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Marine...

  16. 9 CFR 3.118 - Handling.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Handling. 3.118 Section 3.118 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Marine...

  17. 9 CFR 3.118 - Handling.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Handling. 3.118 Section 3.118 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Marine...

  18. 9 CFR 3.118 - Handling.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Handling. 3.118 Section 3.118 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Marine...

  19. 9 CFR 3.118 - Handling.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 1 2011-01-01 2011-01-01 false Handling. 3.118 Section 3.118 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE STANDARDS Specifications for the Humane Handling, Care, Treatment, and Transportation of Marine...

  20. 7 CFR 1207.307 - Handle.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.307 Handle. Handle means to grade, pack, process, sell, transport, purchase, or in any other way to place potatoes or cause potatoes to be placed in the...

  1. 7 CFR 1207.307 - Handle.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.307 Handle. Handle means to grade, pack, process, sell, transport, purchase, or in any other way to place potatoes or cause potatoes to be placed in the...

  2. 7 CFR 1207.307 - Handle.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.307 Handle. Handle means to grade, pack, process, sell, transport, purchase, or in any other way to place potatoes or cause potatoes to be placed in the...

  3. 7 CFR 1207.307 - Handle.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE POTATO RESEARCH AND PROMOTION PLAN Potato Research and Promotion Plan Definitions § 1207.307 Handle. Handle means to grade, pack, process, sell, transport, purchase, or in any other way to place potatoes or cause potatoes to be placed in the...

  4. Magnetic Resonance T2-Relaxometry and 2D L-Correlated Spectroscopy in Patients with Minimal Hepatic Encephalopathy

    PubMed Central

    Singhal, Aparna; Nagarajan, Rajakumar; Kumar, Rajesh; Huda, Amir; Gupta, Rakesh K.; Thomas, M. Albert

    2010-01-01

    Purpose To evaluate T2-relaxation changes in patients with minimal hepatic encephalopathy (MHE) using T2-relaxometry and to correlate T2 values with brain metabolites evaluated using two-dimensional (2D) magnetic resonance spectroscopy (MRS). Materials and Methods Eight MHE patients and 13 healthy subjects were evaluated using T2-relaxometry, and 8 patients and 9 healthy subjects underwent 2D MRS in right frontal and left occipital regions. Whole brain T2-relaxation maps were compared between MHE and control subjects using analysis-of-covariance, with age and gender included as covariates. T2 values derived from the right frontal and left occipital lobes were correlated with the metabolite ratios. Results Multiple brain regions including anterior and mid cingulate cortices, right anterior and left posterior insular cortices, right prefrontal, medial frontal, and right superior temporal cortices showed significantly increased T2 values in MHE patients compared to control subjects. MRS showed significantly increased ratios of glutamine/glutamate (Glx) and decreased ratios of myo-inositol, taurine, choline, and myo-inositol/choline (mICh) with respect to creatine (Cr_d) in patients compared to controls. Frontal Glx/Cr_d showed significantly positive correlation with T2 values. Conclusion MHE patients showed significantly increased T2 values in multiple brain regions reflecting increased free water content and T2 values in frontal lobe correlated with the increased Glx/Cr_d ratio. PMID:19856435

  5. Dynamic response of a sensor element made of magnetic hybrid elastomer with controllable properties

    NASA Astrophysics Data System (ADS)

    Becker, T. I.; Zimmermann, K.; Borin, D. Yu.; Stepanov, G. V.; Storozhenko, P. A.

    2018-03-01

    Smart materials like magnetic hybrid elastomers (MHEs) are based on an elastic composite with a complex hybrid filler of magnetically hard and soft particles. Due to their unique magnetic field depending characteristics, these elastomers offer great potential for designing sensor systems with a complex adaptive behaviour and operating sensitivity. The present paper deals with investigations of the material properties and motion behaviour displayed by synthesised MHE beams in the presence of a uniform magnetic field. The distribution and structure formation of the magnetic components inside the elastic matrix depending on the manufacturing conditions are examined. The specific magnetic features of the MHE material during the magnetising process are revealed. Experimental investigations of the in-plane free vibrational behaviour displayed by the MHE beams with the fixed-free end conditions are performed for various magnitudes of an imposed uniform magnetic field. For the samples pre-magnetised along the length axis, it is demonstrated that the deflection of the beam can be identified unambiguously by magnetic field distortion measurements. It is shown that the material properties of the vibrating MHE element can be specifically adjusted by means of an external magnetic field control. The dependence of the first eigenfrequency of free bending vibrations of the MHE beams on the strength of an imposed uniform magnetic field is obtained. The results are aimed to assess the potential of MHEs to design acceleration sensor systems with an adaptive magnetically controllable sensitivity range.

  6. 50 CFR 14.111 - Handling.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR TAKING, POSSESSION..., EXPORTATION, AND TRANSPORTATION OF WILDLIFE Standards for the Humane and Healthful Transport of Wild Mammals and Birds to the United States § 14.111 Handling. (a) Care shall be exercised to avoid handling the...

  7. SLUG HANDLING DEVICES

    DOEpatents

    Gentry, J.R.

    1958-09-16

    A device is described for handling fuel elements of a neutronic reactor. The device consists of two concentric telescoped contalners that may fit about the fuel element. A number of ratchet members, equally spaced about the entrance to the containers, are pivoted on the inner container and spring biased to the outer container so thnt they are forced to hear against and hold the fuel element, the weight of which tends to force the ratchets tighter against the fuel element. The ratchets are released from their hold by raising the inner container relative to the outer memeber. This device reduces the radiation hazard to the personnel handling the fuel elements.

  8. Radial Internal Material Handling System (RIMS) for Circular Habitat Volumes

    NASA Technical Reports Server (NTRS)

    Howe, Alan S.; Haselschwardt, Sally; Bogatko, Alex; Humphrey, Brian; Patel, Amit

    2013-01-01

    On planetary surfaces, pressurized human habitable volumes will require a means to carry equipment around within the volume of the habitat, regardless of the partial gravity (Earth, Moon, Mars, etc.). On the NASA Habitat Demonstration Unit (HDU), a vertical cylindrical volume, it was determined that a variety of heavy items would need to be carried back and forth from deployed locations to the General Maintenance Work Station (GMWS) when in need of repair, and other equipment may need to be carried inside for repairs, such as rover parts and other external equipment. The vertical cylindrical volume of the HDU lent itself to a circular overhead track and hoist system that allows lifting of heavy objects from anywhere in the habitat to any other point in the habitat interior. In addition, the system is able to hand-off lifted items to other material handling systems through the side hatches, such as through an airlock. The overhead system consists of two concentric circle tracks that have a movable beam between them. The beam has a hoist carriage that can move back and forth on the beam. Therefore, the entire system acts like a bridge crane curved around to meet itself in a circle. The novelty of the system is in its configuration, and how it interfaces with the volume of the HDU habitat. Similar to how a bridge crane allows coverage for an entire rectangular volume, the RIMS system covers a circular volume. The RIMS system is the first generation of what may be applied to future planetary surface vertical cylinder habitats on the Moon or on Mars.

  9. Analysis of multiple activity manual materials handling tasks using A Guide to Manual Materials Handling.

    PubMed

    Mital, A

    1999-01-01

    Manual handling of materials continues to be a hazardous activity, leading to a very significant number of severe overexertion injuries. Designing jobs that are within the physical capabilities of workers is one approach ergonomists have adopted to redress this problem. As a result, several job design procedures have been developed over the years. However, these procedures are limited to designing or evaluating only pure lifting jobs or only the lifting aspect of a materials handling job. This paper describes a general procedure that may be used to design or analyse materials handling jobs that involve several different kinds of activities (e.g. lifting, lowering, carrying, pushing, etc). The job design/analysis procedure utilizes an elemental approach (breaking the job into elements) and relies on databases provided in A Guide to Manual Materials Handling to compute associated risk factors. The use of the procedure is demonstrated with the help of two case studies.

  10. Information Handling is the Problem

    NASA Technical Reports Server (NTRS)

    Malin, Jane T.

    2001-01-01

    This slide presentation reviews the concerns surrounding the automation of information handling. There are two types of decision support software that supports most Space Station Flight Controllers. one is very simple, and the other is very complex. A middle ground is sought. This is the reason for the Human Centered Autonomous and Assistant Systems Testbed (HCAAST) Project. The aim is to study flight controllers at work, and in the bigger picture, with particular attention to how they handle information and how coordination of multiple teams is performed. The focus of the project is on intelligent assistants to assist in handling information for the flight controllers.

  11. 7 CFR 926.9 - Handle.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.9 Handle. Handle... contract carrier of cranberries owned by another person) fresh or processed cranberries produced within or outside the United States or in any other way to place fresh or processed cranberries into the current of...

  12. 7 CFR 926.9 - Handle.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.9 Handle. Handle... contract carrier of cranberries owned by another person) fresh or processed cranberries produced within or outside the United States or in any other way to place fresh or processed cranberries into the current of...

  13. 7 CFR 926.9 - Handle.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.9 Handle. Handle... contract carrier of cranberries owned by another person) fresh or processed cranberries produced within or outside the United States or in any other way to place fresh or processed cranberries into the current of...

  14. 7 CFR 926.9 - Handle.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... REQUIREMENTS APPLICABLE TO CRANBERRIES NOT SUBJECT TO THE CRANBERRY MARKETING ORDER § 926.9 Handle. Handle... contract carrier of cranberries owned by another person) fresh or processed cranberries produced within or outside the United States or in any other way to place fresh or processed cranberries into the current of...

  15. 7 CFR 996.4 - Handle.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... DOMESTIC AND IMPORTED PEANUTS MARKETED IN THE UNITED STATES Definitions § 996.4 Handle. Handle means to... imported peanuts and in the shipment (except as a common or contract carrier of peanuts owned by another) or sale of cleaned-inshell or shelled peanuts or other activity causing peanuts to enter into human...

  16. A new approach to handling incoming verifications.

    PubMed

    Luizzo, Anthony; Roy, Bill; Luizzo, Philip

    2016-10-01

    Outside requests for data on current or former employees are handled in different ways by healthcare organizations and present considerable liability risks if a corporate policy for handling such risks is not in place. In this article, the authors present a strategy for responsible handling of sensitive information.

  17. 9 CFR 114.11 - Storage and handling.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Storage and handling. 114.11 Section... BIOLOGICAL PRODUCTS § 114.11 Storage and handling. Biological products at licensed establishments shall be protected at all times against improper storage and handling. Completed product shall be kept under...

  18. 9 CFR 114.11 - Storage and handling.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Storage and handling. 114.11 Section... BIOLOGICAL PRODUCTS § 114.11 Storage and handling. Biological products at licensed establishments shall be protected at all times against improper storage and handling. Completed product shall be kept under...

  19. 9 CFR 114.11 - Storage and handling.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Storage and handling. 114.11 Section... BIOLOGICAL PRODUCTS § 114.11 Storage and handling. Biological products at licensed establishments shall be protected at all times against improper storage and handling. Completed product shall be kept under...

  20. 14 CFR 25.489 - Ground handling conditions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Ground handling conditions. 25.489 Section... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Structure Ground Loads § 25.489 Ground handling conditions... ground handling conditions). No wing lift may be considered. The shock absorbers and tires may be assumed...

  1. 14 CFR 25.489 - Ground handling conditions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 1 2011-01-01 2011-01-01 false Ground handling conditions. 25.489 Section... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Structure Ground Loads § 25.489 Ground handling conditions... ground handling conditions). No wing lift may be considered. The shock absorbers and tires may be assumed...

  2. Ergonomics of disposable handles for minimally invasive surgery.

    PubMed

    Büchel, D; Mårvik, R; Hallabrin, B; Matern, U

    2010-05-01

    The ergonomic deficiencies of currently available minimally invasive surgery (MIS) instrument handles have been addressed in many studies. In this study, a new ergonomic pistol handle concept, realized as a prototype, and two disposable ring handles were investigated according to ergonomic properties set by new European standards. In this study, 25 volunteers performed four practical tasks to evaluate the ergonomics of the handles used in standard operating procedures (e.g., measuring a suture and cutting to length, precise maneuvering and targeting, and dissection of a gallbladder). Moreover, 20 participants underwent electromyography (EMG) tests to measure the muscle strain they experienced while carrying out the basic functions (grasp, rotate, and maneuver) in the x, y, and z axes. The data measured included the number of errors, the time required for task completion, perception of pressure areas, and EMG data. The values for usability in the test were effectiveness, efficiency, and user satisfaction. Surveys relating to the subjective rating were completed after each task for each of the three handles tested. Each handle except the new prototype caused pressure areas and pain. Extreme differences in muscle strain could not be observed for any of the three handles. Experienced surgeons worked more quickly with the prototype when measuring and cutting a suture (approximately 20%) and during precise maneuvering and targeting (approximately 20%). On the other hand, they completed the dissection task faster with the handle manufactured by Ethicon. Fewer errors were made with the prototype in dissection of the gallbladder. In contrast to the handles available on the market, the prototype was always rated as positive by the volunteers in the subjective surveys. None of the handles could fulfil all of the requirements with top scores. Each handle had its advantages and disadvantages. In contrast to the ring handles, the volunteers could fulfil most of the tasks more

  3. Development and evaluation of a multifaceted ergonomics program to prevent injuries associated with patient handling tasks.

    PubMed

    Nelson, Audrey; Matz, Mary; Chen, Fangfei; Siddharthan, Kris; Lloyd, John; Fragala, Guy

    2006-08-01

    Nurses have one of the highest rates of work-related musculoskeletal injury of any profession. Over the past 30 years, efforts to reduce work-related musculoskeletal disorders in nurses have been largely unsuccessful. The primary goal of this program was to create safer working environments for nursing staff who provide direct patient care. Our first objective was to design and implement a multifaceted program that successfully integrated evidence-based practice, technology, and safety improvement. The second objective was to evaluate the impact of the program on injury rate, lost and modified work days, job satisfaction, self-reported unsafe patient handling acts, level of support for program, staff and patient acceptance, program effectiveness, costs, and return on investment. The intervention included six program elements: (1) Ergonomic Assessment Protocol, (2) Patient Handling Assessment Criteria and Decision Algorithms, (3) Peer Leader role, "Back Injury Resource Nurses", (4) State-of-the-art Equipment, (5) After Action Reviews, and (6) No Lift Policy. A pre-/post design without a control group was used to evaluate the effectiveness of a patient care ergonomics program on 23 high risk units (19 nursing home care units and 4 spinal cord injury units) in 7 facilities. Injury rates, lost work days, modified work days, job satisfaction, staff , and patient acceptance, program effectiveness, and program costs/savings were compared over two nine month periods: pre-intervention (May 2001-January 2002) and post-intervention (March 2002-November 2002). Data were collected prospectively through surveys, weekly process logs, injury logs, and cost logs. The program elements resulted in a statistically significant decrease in the rate of musculoskeletal injuries as well as the number of modified duty days taken per injury. While the total number of lost workdays decreased by 18% post-intervention, this difference was not statistically significant. There were statistically

  4. Coaxial twin-shaft magnetic fluid seals applied in vacuum wafer-handling robot

    NASA Astrophysics Data System (ADS)

    Cong, Ming; Wen, Haiying; Du, Yu; Dai, Penglei

    2012-07-01

    Compared with traditional mechanical seals, magnetic fluid seals have unique characters of high airtightness, minimal friction torque requirements, pollution-free and long life-span, widely used in vacuum robots. With the rapid development of Integrate Circuit (IC), there is a stringent requirement for sealing wafer-handling robots when working in a vacuum environment. The parameters of magnetic fluid seals structure is very important in the vacuum robot design. This paper gives a magnetic fluid seal device for the robot. Firstly, the seal differential pressure formulas of magnetic fluid seal are deduced according to the theory of ferrohydrodynamics, which indicate that the magnetic field gradient in the sealing gap determines the seal capacity of magnetic fluid seal. Secondly, the magnetic analysis model of twin-shaft magnetic fluid seals structure is established. By analyzing the magnetic field distribution of dual magnetic fluid seal, the optimal value ranges of important parameters, including parameters of the permanent magnetic ring, the magnetic pole tooth, the outer shaft, the outer shaft sleeve and the axial relative position of two permanent magnetic rings, which affect the seal differential pressure, are obtained. A wafer-handling robot equipped with coaxial twin-shaft magnetic fluid rotary seals and bellows seal is devised and an optimized twin-shaft magnetic fluid seals experimental platform is built. Test result shows that when the speed of the two rotational shafts ranges from 0-500 r/min, the maximum burst pressure is about 0.24 MPa. Magnetic fluid rotary seals can provide satisfactory performance in the application of wafer-handling robot. The proposed coaxial twin-shaft magnetic fluid rotary seal provides the instruction to design high-speed vacuum robot.

  5. Process and equipment development for hot isostatic pressing treatability study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bateman, Ken; Wahlquist, Dennis; Malewitz, Tim

    2015-03-01

    Battelle Energy Alliance (BEA), LLC, has developed processes and equipment for a pilot-scale hot isostatic pressing (HIP) treatability study to stabilize and volume reduce radioactive calcine stored at Idaho National Laboratory (INL). In 2009, the U. S. Department of Energy signed a Record of Decision with the state of Idaho selecting HIP technology as the method to treat 5,800 yd^3 (4,400 m^3) of granular zirconia and alumina calcine produced between 1953 and 1992 as a waste byproduct of spent nuclear fuel reprocessing. Since the 1990s, a variety of radioactive and hazardous waste forms have been remotely treated using HIP withinmore » INL hot cells. To execute the remote process at INL, waste is loaded into a stainless-steel or aluminum can, which is evacuated, sealed, and placed into a HIP furnace. The HIP simultaneously heats and pressurizes the waste, reducing its volume and increasing its durability. Two 1 gal cans of calcine waste currently stored in a shielded cask were identified as candidate materials for a treatability study involving the HIP process. Equipment and materials for cask-handling and calcine transfer into INL hot cells, as well as remotely operated equipment for waste can opening, particle sizing, material blending, and HIP can loading have been designed and successfully tested. These results demonstrate BEA’s readiness for treatment of INL calcine.« less

  6. SpaceWire: IP, Components, Development Support and Test Equipment

    NASA Astrophysics Data System (ADS)

    Parkes, S.; McClements, C.; Mills, S.; Martin, I.

    SpaceWire is a communications network for use onboard spacecraft. It is designed to connect high data-rate sensors, large solid-state memories, processing units and the downlink telemetry subsystem providing an integrated data-handling network. SpaceWire links are serial, high-speed (2 Mbits/sec to 400 Mbits/sec), bi-directional, full-duplex, pointto- point data links which connect together SpaceWire equipment. Application information is sent along a SpaceWire link in discrete packets. Control and time information can also be sent along SpaceWire links. SpaceWire is defined in the ECSS-E50-12A standard [1]. With the adoption of SpaceWire on many space missions the ready availability of intellectual property (IP) cores, components, software drivers, development support, and test equipment becomes a major issue for those developing satellites and their electronic subsystems. This paper describes the work being done at the University of Dundee and STAR-Dundee Ltd with ESA, BNSC and internal funding to make these essential items available. STAR-Dundee is a spin-out company of the University of Dundee set up specifically to support users of SpaceWire.

  7. 14 CFR 158.49 - Handling of PFC's.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Handling of PFC's. 158.49 Section 158.49... PASSENGER FACILITY CHARGES (PFC'S) Collection, Handling, and Remittance of PFC's § 158.49 Handling of PFC's... amount of PFC revenue in the covered air carrier's account at the time the bankruptcy petition is filed...

  8. 14 CFR 158.49 - Handling of PFC's.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Handling of PFC's. 158.49 Section 158.49... PASSENGER FACILITY CHARGES (PFC'S) Collection, Handling, and Remittance of PFC's § 158.49 Handling of PFC's... amount of PFC revenue in the covered air carrier's account at the time the bankruptcy petition is filed...

  9. 14 CFR 158.49 - Handling of PFC's.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Handling of PFC's. 158.49 Section 158.49... PASSENGER FACILITY CHARGES (PFC'S) Collection, Handling, and Remittance of PFC's § 158.49 Handling of PFC's... amount of PFC revenue in the covered air carrier's account at the time the bankruptcy petition is filed...

  10. 14 CFR 158.49 - Handling of PFC's.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Handling of PFC's. 158.49 Section 158.49... PASSENGER FACILITY CHARGES (PFC'S) Collection, Handling, and Remittance of PFC's § 158.49 Handling of PFC's... amount of PFC revenue in the covered air carrier's account at the time the bankruptcy petition is filed...

  11. 14 CFR 158.49 - Handling of PFC's.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Handling of PFC's. 158.49 Section 158.49... PASSENGER FACILITY CHARGES (PFC'S) Collection, Handling, and Remittance of PFC's § 158.49 Handling of PFC's... amount of PFC revenue in the covered air carrier's account at the time the bankruptcy petition is filed...

  12. Offset-Free Model Predictive Control of Open Water Channel Based on Moving Horizon Estimation

    NASA Astrophysics Data System (ADS)

    Ekin Aydin, Boran; Rutten, Martine

    2016-04-01

    Model predictive control (MPC) is a powerful control option which is increasingly used by operational water managers for managing water systems. The explicit consideration of constraints and multi-objective management are important features of MPC. However, due to the water loss in open water systems by seepage, leakage and evaporation a mismatch between the model and the real system will be created. These mismatch affects the performance of MPC and creates an offset from the reference set point of the water level. We present model predictive control based on moving horizon estimation (MHE-MPC) to achieve offset free control of water level for open water canals. MHE-MPC uses the past predictions of the model and the past measurements of the system to estimate unknown disturbances and the offset in the controlled water level is systematically removed. We numerically tested MHE-MPC on an accurate hydro-dynamic model of the laboratory canal UPC-PAC located in Barcelona. In addition, we also used well known disturbance modeling offset free control scheme for the same test case. Simulation experiments on a single canal reach show that MHE-MPC outperforms disturbance modeling offset free control scheme.

  13. Ground data handling for LANDSAT-D

    NASA Technical Reports Server (NTRS)

    Lynch, T. J.

    1976-01-01

    The present plans for the LANDSAT D ground data handling are described in relationship to the mission objectives and the planned spacecraft system. The end to end data system is presented with particular emphasis on the data handling plans for the new instrument, the Thematic Mapper. This instrument generates ten times the amount of data per scene as the present Multispectral Scanner, and this resulting data rate and volume are discussed as well as possible new data techniques to handle them such as image compression.

  14. Aquatic Equipment Information.

    ERIC Educational Resources Information Center

    Sova, Ruth

    Equipment usually used in water exercise programs is designed for variety, intensity, and program necessity. This guide discusses aquatic equipment under the following headings: (1) equipment design; (2) equipment principles; (3) precautions and contraindications; (4) population contraindications; and (5) choosing equipment. Equipment is used…

  15. Rotorcraft handling-qualities design criteria development

    NASA Technical Reports Server (NTRS)

    Aiken, Edwin W.; Lebacqz, J. Victor; Chen, Robert T. N.; Key, David L.

    1988-01-01

    Joint NASA/Army efforts at the Ames Research Center to develop rotorcraft handling-qualities design criteria began in earnest in 1975. Notable results were the UH-1H VSTOLAND variable stability helicopter, the VFA-2 camera-and-terrain-board simulator visual system, and the generic helicopter real-time mathematical model, ARMCOP. An initial series of handling-qualities studies was conducted to assess the effects of rotor design parameters, interaxis coupling, and various levels of stability and control augmentation. The ability to conduct in-flight handling-qualities research was enhanced by the development of the NASA/Army CH-47 variable-stability helicopter. Research programs conducted using this vehicle include vertical-response investigations, hover augmentation systems, and the effects of control-force characteristics. The handling-qualities data base was judged to be sufficient to allow an update of the military helicopter handling-qualities specification, MIL-H-8501. These efforts, including not only the in-house experimental work but also contracted research and collaborative programs performed under the auspices of various international agreements. The report concludes by reviewing the topics that are currently most in need of work, and the plans for addressing these topics.

  16. Covert hepatic encephalopathy: not as minimal as you might think.

    PubMed

    Kappus, Matthew R; Bajaj, Jasmohan S

    2012-11-01

    Hepatic encephalopathy (HE) is a serious neuropsychiatric and neurocognitive complication of acute and chronic liver disease. Symptoms are often overt (confusion, disorientation, ataxia, or coma) but can also be subtle (difficulty with cognitive abilities such as executive decision-making and psychomotor speed). There is consensus that HE is characterized as a spectrum of neuropsychiatric symptoms in the absence of brain disease, ranging from overt HE (OHE) to minimal HE (MHE). The West Haven Criteria are most often used to grade HE, with scores ranging from 0-4 (4 being coma). However, it is a challenge to diagnose patients with MHE or grade 1 HE; it might be practical to combine these entities and name them covert HE for clinical use. The severity of HE is associated with the stage of liver disease. Although the pathologic mechanisms of HE are not well understood, they are believed to involve increased levels of ammonia and inflammation, which lead to low-grade cerebral edema. A diagnosis of MHE requires dedicated psychometric tests and neurophysiological techniques rather than a simple clinical assessment. Although these tests can be difficult to perform in practice, they are cost effective and important; the disorder affects patients' quality of life, socioeconomic status, and driving ability and increases their risk for falls and the development of OHE. Patients with MHE are first managed by excluding other causes of neurocognitive dysfunction. Therapy with gut-specific agents might be effective. We review management strategies and important areas of research for MHE and covert HE. Copyright © 2012 AGA Institute. Published by Elsevier Inc. All rights reserved.

  17. Urinary cyclophosphamide excretion and micronuclei frequencies in peripheral lymphocytes and in exfoliated buccal epithelial cells of nurses handling antineoplastics.

    PubMed

    Burgaz, S; Karahalil, B; Bayrak, P; Taşkin, L; Yavuzaslan, F; Bökesoy, I; Anzion, R B; Bos, R P; Platin, N

    1999-02-02

    In this study, urinary cyclophosphamide (CP) excretion rate, as well as micronuclei (MN) in peripheral lymphocytes and in buccal epithelial cells were determined for 26 nurses handling antineoplastics and 14 referents matched for age and sex. In urine samples of 20 out of 25 exposed nurses CP excretion rate was found in a range of 0.02-9.14 microg CP/24 h. Our results of the analyses of CP in urine demonstrates that when the nurses were handling CP (and other antineoplastic drugs) this particular compound was observed in urine. The mean values (+/-SD) of MN frequencies (%) in peripheral lymphocytes from the nurses and controls were 0.61 (+/-0. 32) and 0.28 (+/-0.16), respectively (p<0.01). The mean value (+/-SD) of MN frequency (%) in buccal epithelial cells of nurses was 0.16 (+/-0.19) and also mean MN frequency in buccal epithelial cells for controls was found to be as 0.08 (+/-0.08), (p>0.05). Age, sex and smoking habits have not influenced the parameters analyzed in this study. Handling time of antineoplastics, use of protective equipment and handling frequency of drugs have no effect on urinary and cytogenetic parameters analyzed. No correlation was found between the urinary CP excretion and the cytogenetic findings in nurses. Neither could we find any relationship between two cytogenetic endpoints. Our results have identified the possible genotoxic damage of oncology nurses related to occupational exposure to at least one antineoplastic agent, which is used as a marker for drug handling. As a whole, there is concern that the present handling practices of antineoplastic drugs used in the several hospitals in Ankara will not be sufficient to prevent exposure. Copyright 1999 Elsevier Science B.V.

  18. Ergonomics: safe patient handling and mobility.

    PubMed

    Hallmark, Beth; Mechan, Patricia; Shores, Lynne

    2015-03-01

    This article reviews and investigates the issues surrounding ergonomics, with a specific focus on safe patient handling and mobility. The health care worker of today faces many challenges, one of which is related to the safety of patients. Safe patient handling and mobility is on the forefront of the movement to improve patient safety. This article reviews the risks associated with patient handling and mobility, and informs the reader of current evidence-based practice relevant to this area of care. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Exception handling for sensor fusion

    NASA Astrophysics Data System (ADS)

    Chavez, G. T.; Murphy, Robin R.

    1993-08-01

    This paper presents a control scheme for handling sensing failures (sensor malfunctions, significant degradations in performance due to changes in the environment, and errant expectations) in sensor fusion for autonomous mobile robots. The advantages of the exception handling mechanism are that it emphasizes a fast response to sensing failures, is able to use only a partial causal model of sensing failure, and leads to a graceful degradation of sensing if the sensing failure cannot be compensated for. The exception handling mechanism consists of two modules: error classification and error recovery. The error classification module in the exception handler attempts to classify the type and source(s) of the error using a modified generate-and-test procedure. If the source of the error is isolated, the error recovery module examines its cache of recovery schemes, which either repair or replace the current sensing configuration. If the failure is due to an error in expectation or cannot be identified, the planner is alerted. Experiments using actual sensor data collected by the CSM Mobile Robotics/Machine Perception Laboratory's Denning mobile robot demonstrate the operation of the exception handling mechanism.

  20. Highway Maintenance Equipment Operator. Miscellaneous Equipment. Training Materials.

    ERIC Educational Resources Information Center

    Perky, Sandra Dutreau; And Others

    This curriculum guide provides instructional materials to assist in training equipment operators in the safe and effective use of highway maintenance equipment. It includes six units of instruction covering the small, specialized equipment used in maintenance operations. Each unit of instruction consists of eight basic components: performance…

  1. Medical Issues: Equipment

    MedlinePlus

    ... support & care > living with sma > medical issues > equipment Equipment Individuals with SMA often require a range of ... you can submit an equipment pool request. Helpful Equipment The following is a list of equipment that ...

  2. A probabilistic method to diagnose faults of air handling units

    NASA Astrophysics Data System (ADS)

    Dey, Debashis

    Air handling unit (AHU) is one of the most extensively used equipment in large commercial buildings. This device is typically customized and lacks quality system integration which can result in hardwire failures and controller errors. Air handling unit Performance Assessment Rules (APAR) is a fault detection tool that uses a set of expert rules derived from mass and energy balances to detect faults in air handling units. APAR is computationally simple enough that it can be embedded in commercial building automation and control systems and relies only upon sensor data and control signals that are commonly available in these systems. Although APAR has many advantages over other methods, for example no training data required and easy to implement commercially, most of the time it is unable to provide the diagnosis of the faults. For instance, a fault on temperature sensor could be fixed bias, drifting bias, inappropriate location, complete failure. Also a fault in mixing box can be return and outdoor damper leak or stuck. In addition, when multiple rules are satisfied the list of faults increases. There is no proper way to have the correct diagnosis for rule based fault detection system. To overcome this limitation we proposed Bayesian Belief Network (BBN) as a diagnostic tool. BBN can be used to simulate diagnostic thinking of FDD experts through a probabilistic way. In this study we developed a new way to detect and diagnose faults in AHU through combining APAR rules and Bayesian Belief network. Bayesian Belief Network is used as a decision support tool for rule based expert system. BBN is highly capable to prioritize faults when multiple rules are satisfied simultaneously. Also it can get information from previous AHU operating conditions and maintenance records to provide proper diagnosis. The proposed model is validated with real time measured data of a campus building at University of Texas at San Antonio (UTSA).The results show that BBN is correctly able to

  3. Highway Maintenance Equipment Operator. Specialized Equipment. Training Materials.

    ERIC Educational Resources Information Center

    Perky, Sandra Dutreau; And Others

    This curriculum guide provides instructional materials to assist in training equipment operators in the safe and effective use of highway maintenance equipment. It includes 18 units of instruction covering the large equipment used in maintenance operations. Each unit of instruction consists of eight basic components: performance objectives,…

  4. Cost of Information Handling in Hospitals

    PubMed Central

    Jydstrup, Ronald A.; Gross, Malvern J.

    1966-01-01

    Cost of information handling (noncomputerized) in hospitals was studied in detail from an industrial engineering point of view at Rochester General, Highland, and Geneva General hospitals. Activities were observed, personnel questioned, and time studies carried out. It was found that information handling comprises about one fourth of the hospitals' operating cost—a finding strongly recommending revision and streamlining of both forms and inefficient operations. In an Appendix to this study are presented 15 items that would improve information handling in one area of the hospital, nursing units, where this activity is greater than in any other in a hospital. PMID:5971636

  5. Early handling modulates outcome of neonatal dexamethasone exposure.

    PubMed

    Claessens, Sanne E F; Daskalakis, Nikolaos P; Oitzl, Melly S; de Kloet, E Ronald

    2012-09-01

    Synthetic glucocorticoids such as dexamethasone (DEX) are used to prevent or treat respiratory disorders in prematurely born infants. Besides the short-term benefit on lung development, numerous human and animal studies have reported adverse neurodevelopmental side effects. In contrast, maternal care is known to exert a positive influence on neurodevelopmental outcome in rodents. The aim of the current study was therefore to investigate whether neonatal handling (days 1-21), known to induce maternal care, might serve as an intervention strategy modulating the adverse effects of DEX treatment (days 1-3). For this purpose we have measured the outcome of these early-life manipulations on development as well as adult endocrine and behavioral phenotype of male rats. Maternal care was observed during the first week of life and indeed enhanced in response to handling. Eye opening was accelerated and body weight reduced in DEX-treated animals. In adulthood, we report that handling ameliorated impaired spatial learning observed in DEX treated non-handled animals in the T-maze. Additionally, handling reduced susceptibility to the impact of DEX treatment in the water maze. Although DEX treatment and handling both resulted in enhanced negative feedback of the stress-induced corticosterone response and both reduced startle reactivity, the acquisition of fear was only reduced by handling, without effect of DEX. Interestingly, handling had a beneficial effect on pre-pulse inhibition, which was diminished after DEX treatment. In conclusion, these findings indicate that handling of the neonate enhances maternal care and attenuates specific DEX-induced alterations in the adult behavioral phenotype. Copyright © 2012 Elsevier Inc. All rights reserved.

  6. 30 CFR 75.833 - Handling high-voltage trailing cables.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Handling high-voltage trailing cables. 75.833... High-Voltage Longwalls § 75.833 Handling high-voltage trailing cables. (a) Cable handling. (1) Miners must not handle energized trailing cables unless they are wearing high-voltage insulating gloves, which...

  7. Airborne microorganisms associated with grain handling.

    PubMed

    Swan, J R; Crook, B

    1998-01-01

    There is substantial evidence that workers handling grain develop allergic respiratory symptoms. Microbiological contaminants are likely to be a significant contributing factor. Worker's exposure to microorganisms contaminating grain dust in the UK was therefore examined. Aerobiological studies were made when grain was being handled on farms and also during bulk handling of grain in dockside terminals. A quantitative and qualitative microbiological examination of the airborne grain dust was carried out. Samples of airborne grain dust were collected and viable bacteria, fungi and actinomycetes were grown, isolated and identified. It was found that workers handling grain or working close to grain at farms and docks were frequently exposed to more than 1 million bacteria and fungi per m3 air, and that airborne bacteria and fungi exceeded 10(4) per m3 air in all areas sampled. The qualitative examination of the samples showed that the predominant microorganisms present differed between freshly harvested grain and stored grain, but not between different types of grain.

  8. Procedures and equipment for staining large numbers of plant root samples for endomycorrhizal assay.

    PubMed

    Kormanik, P P; Bryan, W C; Schultz, R C

    1980-04-01

    A simplified method of clearing and staining large numbers of plant roots for vesicular-arbuscular (VA) mycorrhizal assay is presented. Equipment needed for handling multiple samples is described, and two formulations for the different chemical solutions are presented. Because one formulation contains phenol, its use should be limited to basic studies for which adequate laboratory exhaust hoods are available and great clarity of fungal structures is required. The second staining formulation, utilizing lactic acid instead of phenol, is less toxic, requires less elaborate laboratory facilities, and has proven to be completely satisfactory for VA assays.

  9. Human Handling Promotes Compliant Behavior in Adult Laboratory Rabbits

    PubMed Central

    Swennes, Alton G; Alworth, Leanne C; Harvey, Stephen B; Jones, Carolyn A; King, Christopher S; Crowell-Davis, Sharon L

    2011-01-01

    Routine laboratory procedures can be stressful for laboratory animals. We wanted to determine whether human handling of adult rabbits could induce a degree of habituation, reducing stress and facilitating research-related manipulation. To this end, adult New Zealand white rabbits were handled either frequently or minimally. After being handled over 3 wk, these rabbits were evaluated by novel personnel and compared with minimally handled controls. Evaluators subjectively scored the rabbits for their relative compliance or resistance to being scruffed and removed from their cages, being transported to a treatment room, and their behavior at all stages of the exercise. Upon evaluation, handled rabbits scored significantly more compliant than nontreated controls. During evaluation, behaviors that the rabbits displayed when they were approached in their cages and while being handled outside their cages were recorded and compared between study groups. Handled rabbits displayed behavior consistent with a reduction in human-directed fear. This study illustrates the potential for handling to improve compliance in laboratory procedures and reduce fear-related behavior in laboratory rabbits. Such handling could be used to improve rabbit welfare through the reduction of stress and exposure to novel stimuli. PMID:21333162

  10. Terminal homing position estimation forAutonomous underwater vehicle docking

    DTIC Science & Technology

    2017-06-01

    used by the AUV to improve its position estimate. Due to the nonlinearity of the D-USBL measurements, the Extended Kalman Filter (EKF), Unscented...Kalman Filter (UKF) and forward and backward smoothing (FBS) filter were utilized to estimate the position of the AUV. After performance of these... filters was deemed unsatisfactory, a new smoothing technique called the Moving Horizon Estimation (MHE) with epi-splines was introduced. The MHE

  11. 7 CFR 959.53 - Handling for special purposes.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Handling for special purposes. 959.53 Section 959.53 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing... Regulating Handling Regulations § 959.53 Handling for special purposes. Regulations in effect pursuant to...

  12. Handle-shaped Prominence

    NASA Image and Video Library

    2001-02-17

    NASA Extreme Ultraviolet Imaging Telescope aboard ESA’s SOHO spacecraft took this image of a huge, handle-shaped prominence in 1999. Prominences are huge clouds of relatively cool dense plasma suspended in the Sun hot, thin corona.

  13. Handling Qualities Optimization for Rotorcraft Conceptual Design

    NASA Technical Reports Server (NTRS)

    Lawrence, Ben; Theodore, Colin R.; Berger, Tom

    2016-01-01

    Over the past decade, NASA, under a succession of rotary-wing programs has been moving towards coupling multiple discipline analyses in a rigorous consistent manner to evaluate rotorcraft conceptual designs. Handling qualities is one of the component analyses to be included in a future NASA Multidisciplinary Analysis and Optimization framework for conceptual design of VTOL aircraft. Similarly, the future vision for the capability of the Concept Design and Assessment Technology Area (CD&A-TA) of the U.S Army Aviation Development Directorate also includes a handling qualities component. SIMPLI-FLYD is a tool jointly developed by NASA and the U.S. Army to perform modeling and analysis for the assessment of flight dynamics and control aspects of the handling qualities of rotorcraft conceptual designs. An exploration of handling qualities analysis has been carried out using SIMPLI-FLYD in illustrative scenarios of a tiltrotor in forward flight and single-main rotor helicopter at hover. Using SIMPLI-FLYD and the conceptual design tool NDARC integrated into a single process, the effects of variations of design parameters such as tail or rotor size were evaluated in the form of margins to fixed- and rotary-wing handling qualities metrics as well as the vehicle empty weight. The handling qualities design margins are shown to vary across the flight envelope due to both changing flight dynamic and control characteristics and changing handling qualities specification requirements. The current SIMPLI-FLYD capability and future developments are discussed in the context of an overall rotorcraft conceptual design process.

  14. Open-Source Assisted Laboratory Automation through Graphical User Interfaces and 3D Printers: Application to Equipment Hyphenation for Higher-Order Data Generation.

    PubMed

    Siano, Gabriel G; Montemurro, Milagros; Alcaráz, Mirta R; Goicoechea, Héctor C

    2017-10-17

    Higher-order data generation implies some automation challenges, which are mainly related to the hidden programming languages and electronic details of the equipment. When techniques and/or equipment hyphenation are the key to obtaining higher-order data, the required simultaneous control of them demands funds for new hardware, software, and licenses, in addition to very skilled operators. In this work, we present Design of Inputs-Outputs with Sikuli (DIOS), a free and open-source code program that provides a general framework for the design of automated experimental procedures without prior knowledge of programming or electronics. Basically, instruments and devices are considered as nodes in a network, and every node is associated both with physical and virtual inputs and outputs. Virtual components, such as graphical user interfaces (GUIs) of equipment, are handled by means of image recognition tools provided by Sikuli scripting language, while handling of their physical counterparts is achieved using an adapted open-source three-dimensional (3D) printer. Two previously reported experiments of our research group, related to fluorescence matrices derived from kinetics and high-performance liquid chromatography, were adapted to be carried out in a more automated fashion. Satisfactory results, in terms of analytical performance, were obtained. Similarly, advantages derived from open-source tools assistance could be appreciated, mainly in terms of lesser intervention of operators and cost savings.

  15. 16 CFR 1207.10 - Handling, storage, and marking.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Handling, storage, and marking. 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

  16. 16 CFR 1207.10 - Handling, storage, and marking.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Handling, storage, and marking. 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

  17. 16 CFR 1207.10 - Handling, storage, and marking.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Handling, storage, and marking. 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

  18. 16 CFR 1207.10 - Handling, storage, and marking.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Handling, storage, and marking. 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

  19. Advanced Curation Protocols for Mars Returned Sample Handling

    NASA Astrophysics Data System (ADS)

    Bell, M.; Mickelson, E.; Lindstrom, D.; Allton, J.

    Introduction: Johnson Space Center has over 30 years experience handling precious samples which include Lunar rocks and Antarctic meteorites. However, we recognize that future curation of samples from such missions as Genesis, Stardust, and Mars S mple Return, will require a high degree of biosafety combined witha extremely low levels of inorganic, organic, and biological contamination. To satisfy these requirements, research in the JSC Advanced Curation Lab is currently focused toward two major areas: preliminary examination techniques and cleaning and verification techniques . Preliminary Examination Techniques : In order to minimize the number of paths for contamination we are exploring the synergy between human &robotic sample handling in a controlled environment to help determine the limits of clean curation. Within the Advanced Curation Laboratory is a prototype, next-generation glovebox, which contains a robotic micromanipulator. The remotely operated manipulator has six degrees-of- freedom and can be programmed to perform repetitive sample handling tasks. Protocols are being tested and developed to perform curation tasks such as rock splitting, weighing, imaging, and storing. Techniques for sample transfer enabling more detailed remote examination without compromising the integrity of sample science are also being developed . The glovebox is equipped with a rapid transfer port through which samples can be passed without exposure. The transfer is accomplished by using a unique seal and engagement system which allows passage between containers while maintaining a first seal to the outside environment and a second seal to prevent the outside of the container cover and port door from becoming contaminated by the material being transferred. Cleaning and Verification Techniques: As part of the contamination control effort, innovative cleaning techniques are being identified and evaluated in conjunction with sensitive cleanliness verification methods. Towards this

  20. 30 CFR 77.606 - Energized trailing cables; handling.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Energized trailing cables; handling. 77.606... COAL MINES Trailing Cables § 77.606 Energized trailing cables; handling. Energized medium- and high-voltage trailing cables shall be handled only by persons wearing protective rubber gloves (see § 77.606-1...

  1. Materials Handling. Module SH-01. Safety and Health.

    ERIC Educational Resources Information Center

    Center for Occupational Research and Development, Inc., Waco, TX.

    This student module on materials handling is one of 50 modules concerned with job safety and health. It presents the procedures for safe materials handling. Discussed are manual handling methods (lifting and carrying by hand) and mechanical lifting (lifting by powered trucks, cranes or conveyors). Following the introduction, 15 objectives (each…

  2. Incorporating Handling Qualities Analysis into Rotorcraft Conceptual Design

    NASA Technical Reports Server (NTRS)

    Lawrence, Ben

    2014-01-01

    This paper describes the initial development of a framework to incorporate handling qualities analyses into a rotorcraft conceptual design process. In particular, the paper describes how rotorcraft conceptual design level data can be used to generate flight dynamics models for handling qualities analyses. Also, methods are described that couple a basic stability augmentation system to the rotorcraft flight dynamics model to extend analysis to beyond that of the bare airframe. A methodology for calculating the handling qualities characteristics of the flight dynamics models and for comparing the results to ADS-33E criteria is described. Preliminary results from the application of the handling qualities analysis for variations in key rotorcraft design parameters of main rotor radius, blade chord, hub stiffness and flap moment of inertia are shown. Varying relationships, with counteracting trends for different handling qualities criteria and different flight speeds are exhibited, with the action of the control system playing a complex part in the outcomes. Overall, the paper demonstrates how a broad array of technical issues across flight dynamics stability and control, simulation and modeling, control law design and handling qualities testing and evaluation had to be confronted to implement even a moderately comprehensive handling qualities analysis of relatively low fidelity models. A key outstanding issue is to how to 'close the loop' with an overall design process, and options for the exploration of how to feedback handling qualities results to a conceptual design process are proposed for future work.

  3. Clues for minimal hepatic encephalopathy in children with noncirrhotic portal hypertension.

    PubMed

    D'Antiga, Lorenzo; Dacchille, Patrizia; Boniver, Clementina; Poledri, Sara; Schiff, Sami; Zancan, Lucia; Amodio, Piero

    2014-12-01

    In children with noncirrhotic extrahepatic portal vein obstruction (EHPVO), minimal hepatic encephalopathy (MHE) was reported in a few series, but neither is it routinely investigated nor does consensus about its diagnosis exist. In this prospective observational study we aimed at detecting the prevalence of MHE in children with EHPVO and providing a practical diagnostic protocol. A consecutive sample of 13 noncirrhotic children (age range 4-18 years) with EHPVO underwent a screening for MHE based on level of fasting ammonia, quantified electroencephalogram (EEG) evaluation, and a wide battery of 26 psychometric tests exploring learning ability, abstract reasoning, phonemic and semantic fluency, selective attention, executive functions, short-term verbal and visual memory, long-term verbal memory, and visuopractic ability. Five children had at least 2 altered psychometric tests. Selective attention, executive function, and short-term visual memory were the domains more frequently altered, and 4 tests were enough to detect 80% of these children. Fasting ammonia plasma level was increased in 6 children. EEG mean dominant frequency adjusted for age was associated with serum ammonia concentration (β = -0.44 ± 0.19, P < 0.05). As a whole, children with EHPVO showed trends for lower α (median 41% vs 49%) and higher θ power than controls (median 41% vs 49% and 29% vs 20%, respectively). MHE affects approximately 50% of children with EHPVO and, therefore, is worthwhile to be investigated. Three simple tools, serum ammonia, quantified EEG, and neuropsychological examination, focused on selective attention, executive function, and short-term visual memory can be used effectively in the evaluation of MHE in this setting.

  4. Enhancement of functional connectivity, working memory and inhibitory control on multi-modal brain MR imaging with Rifaximin in Cirrhosis: implications for the gut-liver-brain axis.

    PubMed

    Ahluwalia, Vishwadeep; Wade, James B; Heuman, Douglas M; Hammeke, Thomas A; Sanyal, Arun J; Sterling, Richard K; Stravitz, R Todd; Luketic, Velimir; Siddiqui, Mohammad S; Puri, Puneet; Fuchs, Michael; Lennon, Micheal J; Kraft, Kenneth A; Gilles, HoChong; White, Melanie B; Noble, Nicole A; Bajaj, Jasmohan S

    2014-12-01

    Minimal hepatic encephalopathy (MHE) impairs daily functioning in cirrhosis, but its functional brain impact is not completely understood. To evaluate the effect of rifaximin, a gut-specific antibiotic, on the gut-liver-brain axis in MHE. Rifaximin will reduce endotoxemia, enhance cognition, increase activation during working memory(N-back) and reduce activation needed for inhibitory control tasks. Cirrhotics with MHE underwent baseline endotoxin and cognitive testing, then underwent fMRI, diffusion tensor imaging and MR spectroscopy(MRS). On fMRI, two tasks; N-back (outcome: correct responses) and inhibitory control tests(outcomes: lure inhibition) were performed. All procedures were repeated after 8 weeks of rifaximin. RESULTS were compared before/after rifaximin. 20 MHE patients (59.7 years) were included; sixteen completed pre/post-rifaximin scanning with 92% medication compliance. Pre-rifaximin patients had cognitive impairment. At trial-end, there was a significantly higher correct 2-back responses, ICT lure inhibitions and reduced endotoxemia(p = 0.002). This was accompanied by significantly higher activation from baseline in subcortical structures (thalamus, caudate, insula and hippocampus) and left parietal operculum (LPO) during N-back, decrease in fronto-parietal activation required for inhibiting lures, including LPO during ICT compared to baseline values. Connectivity studies in N-back showed significant shifts in linkages after therapy in fronto-parietal regions with a reduction in fractional anisotropy (FA) but not mean diffusivity (MD), and no change in MRS metabolites at the end of the trial. A significant improvement in cognition including working memory and inhibitory control, and fractional anisotropy without effect on MD or MRS, through modulation of fronto-parietal and subcortical activation and connectivity was seen after open-label rifaximin therapy in MHE.

  5. Resveratrol in Patients with Minimal Hepatic Encephalopathy

    PubMed Central

    Bertino, Gaetano; Motta, Massimo; Borzì, Antonio Maria; Vicari, Enzo; Bella, Rita; Drago, Filippo

    2018-01-01

    Background: Minimal Hepatic Encephalopathy (MHE) is characterized by an impairment of social interaction, emotional behavior, sleep disorders, physical and mental symptoms, and diminished Quality of Life (QoL). The aim of our study is evaluating the potential liver health promoting a perspective of Resveratrol (RV) activities and evaluate whether RV treatment may improve health related quality of life (HRQL) and reduce depression and anxiety in patients with MHE. Methods: We evaluated depression using the Beck Depression Inventory test, anxiety with State-trait anxiety inventory test, quality of life through SF-36 test, and ammonia serum levels in 70 MHE patients that were randomized into two groups. Results: In the comparison between RV group and placebo group we observed a decrease in Back Depression Inventory (BDI) (p < 0.001), in State-trait anxiety inventory (STAI) (p < 0.001), and improve in physical function (p < 0.001), in role physical (p < 0.05), in body pain (p < 0.05), in general health (p < 0.001), in vitality (p < 0.05), and in social function (p < 0.001). Conclusions: Resveratrol showed efficacy in the treatment of depression, anxiety, and ammonia serum levels, and improved the quality of life Of MHE patients. PMID:29522439

  6. How to Handle Impasses in Bargaining.

    ERIC Educational Resources Information Center

    Durrant, Robert E.

    Guidelines in an outline format are presented to school board members and administrators on how to handle impasses in bargaining. The following two rules are given: there sometimes may be strikes, but there always will be settlements; and on the way to settlements, there always will be impasses. Suggestions for handling impasses are listed under…

  7. Neonatal handling and reproductive function in female rats.

    PubMed

    Gomes, C M; Raineki, C; Ramos de Paula, P; Severino, G S; Helena, C V V; Anselmo-Franci, J A; Franci, C R; Sanvitto, G L; Lucion, A B

    2005-02-01

    Neonatal handling induces anovulatory estrous cycles and decreases sexual receptivity in female rats. The synchronous secretion of hormones from the gonads (estradiol (E2) and progesterone (P)), pituitary (luteinizing (LH) and follicle-stimulating (FSH) hormones) and hypothalamus (LH-releasing hormone (LHRH)) are essential for the reproductive functions in female rats. The present study aimed to describe the plasma levels of E2 and P throughout the estrous cycle and LH, FSH and prolactin (PRL) in the afternoon of the proestrus, and the LHRH content in the medial preoptic area (MPOA), median eminence (ME) and medial septal area (MSA) in the proestrus, in the neonatal handled rats. Wistar pup rats were handled for 1 min during the first 10 days after delivery (neonatal handled group) or left undisturbed (nonhandled group). When they reached adulthood, blood samples were collected through a jugular cannula and the MPOA, ME and MSA were microdissected. Plasma levels of the hormones and the content of LHRH were determined by RIA. The number of oocytes counted in the morning of the estrus day in the handled rats was significantly lower than in the nonhandled ones. Neonatal handling reduces E2 levels only on the proestrus day while P levels decreased in metestrus and estrus. Handled females also showed reduced plasma levels of LH, FSH and PRL in the afternoon of the proestrus. The LHRH content in the MPOA was significantly higher than in the nonhandled group. The reduced secretion of E2, LH, FSH and LHRH on the proestrus day may explain the anovulatory estrous cycle in neonatal handled rats. The reduced secretion of PRL in the proestrus may be related to the decreased sexual receptiveness in handled females. In conclusion, early-life environmental stimulation can induce long-lasting effects on the hypothalamus-pituitary-gonad axis.

  8. Quinone-induced protein handling changes: Implications for major protein handling systems in quinone-mediated toxicity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xiong, Rui; Siegel, David; Ross, David, E-mail: david.ross@ucdenver.edu

    2014-10-15

    Para-quinones such as 1,4-Benzoquinone (BQ) and menadione (MD) and ortho-quinones including the oxidation products of catecholamines, are derived from xenobiotics as well as endogenous molecules. The effects of quinones on major protein handling systems in cells; the 20/26S proteasome, the ER stress response, autophagy, chaperone proteins and aggresome formation, have not been investigated in a systematic manner. Both BQ and aminochrome (AC) inhibited proteasomal activity and activated the ER stress response and autophagy in rat dopaminergic N27 cells. AC also induced aggresome formation while MD had little effect on any protein handling systems in N27 cells. The effect of NQO1more » on quinone induced protein handling changes and toxicity was examined using N27 cells stably transfected with NQO1 to generate an isogenic NQO1-overexpressing line. NQO1 protected against BQ–induced apoptosis but led to a potentiation of AC- and MD-induced apoptosis. Modulation of quinone-induced apoptosis in N27 and NQO1-overexpressing cells correlated only with changes in the ER stress response and not with changes in other protein handling systems. These data suggested that NQO1 modulated the ER stress response to potentiate toxicity of AC and MD, but protected against BQ toxicity. We further demonstrated that NQO1 mediated reduction to unstable hydroquinones and subsequent redox cycling was important for the activation of the ER stress response and toxicity for both AC and MD. In summary, our data demonstrate that quinone-specific changes in protein handling are evident in N27 cells and the induction of the ER stress response is associated with quinone-mediated toxicity. - Highlights: • Unstable hydroquinones contributed to quinone-induced ER stress and toxicity.« less

  9. The influence of handling qualities on safety and survivability

    NASA Technical Reports Server (NTRS)

    Anderson, S. B.

    1977-01-01

    The relationship of handling qualities to safety and survivability of military aircraft is examined which includes the following: (1) a brief discussion of the philosophy used in the military specifications for treatment of degraded handling qualities, (2) an examination of several example handling qualities problem areas which influence safety and survivability; and (3) a movie illustrating the potential dangers of inadequate handling qualities features.

  10. Handling Kids in Crisis with Care

    ERIC Educational Resources Information Center

    Bushinski, Cari

    2018-01-01

    The Handle with Care program helps schools help students who experience trauma. While at the scene of an event like a domestic violence call, drug raid, or car accident, law enforcement personnel determine the names and school of any children present. They notify that child's school to "handle ___ with care" the next day, and the school…

  11. Dielectric Elastomer Actuators for Soft Wave-Handling Systems.

    PubMed

    Wang, Tao; Zhang, Jinhua; Hong, Jun; Wang, Michael Yu

    2017-03-01

    This article presents a soft handling system inspired by the principle of the natural wave (named Wave-Handling system) aiming to offer a soft solution to delicately transport and sort fragile items such as fruits, vegetables, biological tissues in food, and biological industries. The system consists of an array of hydrostatically coupled dielectric elastomer actuators (HCDEAs). Due to the electrostriction property of dielectric elastomers, the handling system can be controlled by electric voltage rather than the cumbersome pneumatic system. To study the working performance of the Wave-Handling system and how the performance can be improved, the basic properties of HCDEA are investigated through experiments. We find that the HCDEA exhibits some delay and hysteretic characteristics when activated by periodic voltage and the characteristics are influenced by the frequency and external force also. All this will affect the performance of the Wave-Handling system. However, the electric control, simple structure, light weight, and low cost of the soft handling system show great potential to move from laboratory to practical application. As a proof of design concept, a simply made prototype of the handling system is controlled to generate a parallel moving wave to manipulate a ball. Based on the experimental results, the improvements and future work are discussed and we believe this work will provide inspiration for soft robotic engineering.

  12. Manipulation and handling processes off-line programming and optimization with use of K-Roset

    NASA Astrophysics Data System (ADS)

    Gołda, G.; Kampa, A.

    2017-08-01

    Contemporary trends in development of efficient, flexible manufacturing systems require practical implementation of modern “Lean production” concepts for maximizing customer value through minimizing all wastes in manufacturing and logistics processes. Every FMS is built on the basis of automated and robotized production cells. Except flexible CNC machine tools and other equipments, the industrial robots are primary elements of the system. In the studies, authors look for wastes of time and cost in real tasks of robots, during manipulation processes. According to aspiration for optimization of handling and manipulation processes with use of the robots, the application of modern off-line programming methods and computer simulation, is the best solution and it is only way to minimize unnecessary movements and other instructions. The modelling process of robotized production cell and offline programming of Kawasaki robots in AS-Language will be described. The simulation of robotized workstation will be realized with use of virtual reality software K-Roset. Authors show the process of industrial robot’s programs improvement and optimization in terms of minimizing the number of useless manipulator movements and unnecessary instructions. This is realized in order to shorten the time of production cycles. This will also reduce costs of handling, manipulations and technological process.

  13. Bisphenol A exposure through receipt handling and its association with insulin resistance among female cashiers.

    PubMed

    Lee, Inae; Kim, Sunmi; Kim, Ki-Tae; Kim, Sungkyoon; Park, Suhyun; Lee, Hyojin; Jeong, Yunsun; Lim, Jae-Eun; Moon, Hyo-Bang; Choi, Kyungho

    2018-05-16

    Bisphenol A (BPA) is one of the most widely used chemicals in various consumer products. In thermal papers such as receipts and tickets, BPA is used as a heat-activated developer. Cashiers are therefore suspected to be a vulnerable group of exposure to BPA, but neither contribution of receipt handling to the total body burden of BPA among cashiers, nor related health effects are well characterized. Female cashiers (n = 54) were recruited from seven retail shops of a major supermarket chain in Korea, and urinary levels of BPA and metabolic syndrome (MetS) related biomarkers were measured. In order to estimate the contribution of receipt handling to the body burden of BPA, an intervention was designed on the use of gloves: the subjects were asked not to wear gloves during the work for one week, and in the following week, to wear gloves. Urine samples were collected at pre-shift and post-shift for the first two consecutive days in each week, and urinary BPA concentrations were measured. In cashiers without gloves, about a two-fold increase in urinary BPA concentrations was observed after work-shift. When the cashiers wore gloves, however, urinary BPA levels showed no changes. Higher urinary BPA concentrations were associated with greater levels of fasting insulin and insulin resistance. Our observation shows that receipt handling among the cashiers could double the BPA exposure levels at post-shift compared to those at pre-shift, and use of simple protective equipment such as gloves could effectively reduce the BPA exposure levels. Copyright © 2018 Elsevier Ltd. All rights reserved.

  14. Overseas Absentee Ballot Handling in DOD

    DTIC Science & Technology

    2001-06-22

    Performed . We reviewed pertinent laws, policies, and guidance dated from May 1980 through January 2000 related to the absentee ballot process and the...OVERSEAS ABSENTEE BALLOT HANDLING IN DOD Report No. D-2001-145 June 22, 2001 Office of the Inspector...34) Title and Subtitle Overseas Absentee Ballot Handling in DOD Contract or Grant Number Program Element Number Authors Project Number Task Number

  15. Power-Tool Adapter For T-Handle Screws

    NASA Technical Reports Server (NTRS)

    Deloach, Stephen R.

    1992-01-01

    Proposed adapter enables use of pneumatic drill, electric drill, electric screwdriver, or similar power tool to tighten or loosen T-handled screws. Notched tube with perpendicular rod welded to it inserted in chuck of tool. Notched end of tube slipped over screw handle.

  16. Direct handling of equality constraints in multilevel optimization

    NASA Technical Reports Server (NTRS)

    Renaud, John E.; Gabriele, Gary A.

    1990-01-01

    In recent years there have been several hierarchic multilevel optimization algorithms proposed and implemented in design studies. Equality constraints are often imposed between levels in these multilevel optimizations to maintain system and subsystem variable continuity. Equality constraints of this nature will be referred to as coupling equality constraints. In many implementation studies these coupling equality constraints have been handled indirectly. This indirect handling has been accomplished using the coupling equality constraints' explicit functional relations to eliminate design variables (generally at the subsystem level), with the resulting optimization taking place in a reduced design space. In one multilevel optimization study where the coupling equality constraints were handled directly, the researchers encountered numerical difficulties which prevented their multilevel optimization from reaching the same minimum found in conventional single level solutions. The researchers did not explain the exact nature of the numerical difficulties other than to associate them with the direct handling of the coupling equality constraints. The coupling equality constraints are handled directly, by employing the Generalized Reduced Gradient (GRG) method as the optimizer within a multilevel linear decomposition scheme based on the Sobieski hierarchic algorithm. Two engineering design examples are solved using this approach. The results show that the direct handling of coupling equality constraints in a multilevel optimization does not introduce any problems when the GRG method is employed as the internal optimizer. The optimums achieved are comparable to those achieved in single level solutions and in multilevel studies where the equality constraints have been handled indirectly.

  17. Redefining NHS complaint handling--the real challenge.

    PubMed

    Seelos, L; Adamson, C

    1994-01-01

    More and more organizations find that a constructive and open dialogue with their customers can be an effective strategy for building long-term customer relations. In this context, it has been recognized that effective complaint-contact handling can make a significant contribution to organizations' attempts to maximize customer satisfaction and loyalty. Within the NHS, an intellectual awareness exists that effective complaint/contact handling can contribute to making services more efficient and cost-effective by developing customer-oriented improvement initiatives. Recent efforts have focused on redefining NHS complaint-handling procedures to make them more user-friendly and effective for both NHS employees and customers. Discusses the challenges associated with opening up the NHS to customer feedback. Highlights potential weaknesses in the current approach and argues that the real challenge is for NHS managers to facilitate a culture change that moves the NHS away from a long-established defensive complaint handling practice.

  18. 4th Day of Equipment Being Loaded for Recovery of Orion

    NASA Image and Video Library

    2014-11-20

    The Orion handling fixture, special bumpers and other ground support equipment are secured in the well deck of the USS Anchorage at Naval Base San Diego in California. The equipment will be used during recovery of the Orion crew module after its first flight test. Before launch of Orion on a Delta IV Heavy rocket from Cape Canaveral Air Force Station in Florida, NASA, Lockheed Martin and U.S. Navy personnel will head out to sea in the USS Anchorage and the USNS Salvor, a salvage ship, and wait for splashdown of the Orion crew module in the Pacific Ocean. The Ground Systems Development and Operations Program will lead the recovery efforts. Orion is the exploration spacecraft designed to carry astronauts to destinations not yet explored by humans, including an asteroid and Mars. It will have emergency abort capability, sustain the crew during space travel and provide safe re-entry from deep space return velocities. The first unpiloted flight test of Orion is scheduled to launch in December atop a United Launch Alliance Delta IV Heavy rocket and in 2018 on NASA’s Space Launch System rocket.

  19. 4th Day of Equipment Being Loaded for Recovery of Orion

    NASA Image and Video Library

    2014-11-20

    The Orion handling fixture and other ground support equipment is secured in the well deck of the USS Anchorage at Naval Base San Diego in California. The equipment will be used during recovery of the Orion crew module after its first flight test. Before launch of Orion on a Delta IV Heavy rocket from Cape Canaveral Air Force Station in Florida, NASA, Lockheed Martin and U.S. Navy personnel will head out to sea in the USS Anchorage and the USNS Salvor, a salvage ship, and wait for splashdown of the Orion crew module in the Pacific Ocean. The Ground Systems Development and Operations Program will lead the recovery efforts. Orion is the exploration spacecraft designed to carry astronauts to destinations not yet explored by humans, including an asteroid and Mars. It will have emergency abort capability, sustain the crew during space travel and provide safe re-entry from deep space return velocities. The first unpiloted flight test of Orion is scheduled to launch in December atop a United Launch Alliance Delta IV Heavy rocket and in 2018 on NASA’s Space Launch System rocket.

  20. Power Product Equipment Technician: Lawn and Garden Equipment. Teacher Edition. Student Version.

    ERIC Educational Resources Information Center

    Hilley, Robert

    This packet contains teacher and student editions for lawn and garden equipment repair and maintenance, intended for the preparation of power product equipment technicians. This publication contains four units: (1) introduction to lawn and garden equipment; (2) light-duty lawn and garden equipment; (3) heavy-duty lawn and garden equipment; and (4)…

  1. 49 CFR 176.57 - Supervision of handling and stowage.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 2 2011-10-01 2011-10-01 false Supervision of handling and stowage. 176.57 Section 176.57 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS... VESSEL General Handling and Stowage § 176.57 Supervision of handling and stowage. (a) Hazardous materials...

  2. 49 CFR 176.57 - Supervision of handling and stowage.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 49 Transportation 2 2014-10-01 2014-10-01 false Supervision of handling and stowage. 176.57 Section 176.57 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS... VESSEL General Handling and Stowage § 176.57 Supervision of handling and stowage. (a) Hazardous materials...

  3. 49 CFR 176.57 - Supervision of handling and stowage.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 2 2012-10-01 2012-10-01 false Supervision of handling and stowage. 176.57 Section 176.57 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS... VESSEL General Handling and Stowage § 176.57 Supervision of handling and stowage. (a) Hazardous materials...

  4. 49 CFR 176.57 - Supervision of handling and stowage.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Supervision of handling and stowage. 176.57 Section 176.57 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS... VESSEL General Handling and Stowage § 176.57 Supervision of handling and stowage. (a) Hazardous materials...

  5. 49 CFR 176.57 - Supervision of handling and stowage.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 2 2013-10-01 2013-10-01 false Supervision of handling and stowage. 176.57 Section 176.57 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS... VESSEL General Handling and Stowage § 176.57 Supervision of handling and stowage. (a) Hazardous materials...

  6. Enhancement of Functional Connectivity, Working Memory and Inhibitory Control on Multi-modal Brain MR Imaging with Rifaximin in Cirrhosis: Implications for the Gut-Liver-Brain Axis

    PubMed Central

    Ahluwalia, Vishwadeep; Wade, James B; Heuman, Douglas M; Hammeke, Thomas A; Sanyal, Arun J; Sterling, Richard K; Stravitz, R. Todd; Luketic, Velimir; Siddiqui, Mohammad S; Puri, Puneet; Fuchs, Michael; Lennon, Micheal J; Kraft, Kenneth A; Gilles, HoChong; White, Melanie B; Noble, Nicole A; Bajaj, Jasmohan S

    2014-01-01

    Objective Minimal hepatic encephalopathy (MHE) impairs daily functioning in cirrhosis, but its functional brain impact is not completely understood. Aim To evaluate the effect of rifaximin, a gut-specific antibiotic, on the gut-liver-brain axis in MHE. Hypothesis Rifaximin will reduce endotoxemia, enhance cognition, increase activation during working memory(N-back) and reduce activation needed for inhibitory control tasks. Methods Cirrhotics with MHE underwent baseline endotoxin and cognitive testing, then underwent fMRI, diffusion tensor imaging and MR spectroscopy(MRS). On fMRI, two tasks; N-back (outcome: correct responses) and inhibitory control tests(outcomes: lure inhibition) were performed. All procedures were repeated after 8 weeks of rifaximin. Results were compared before/after rifaximin. Results 20 MHE patients (59.7 years) were included; sixteen completed pre/post-rifaximin scanning with 92% medication compliance. Pre-rifaximin patients had cognitive impairment. At trial-end, there was a significantly higher correct 2-back responses, ICT lure inhibitions and reduced endotoxemia(p=0.002). This was accompanied by significantly higher activation from baseline in subcortical structures (thalamus, caudate, insula and hippocampus) and left parietal operculum (LPO) during N-back, decrease in fronto-parietal activation required for inhibiting lures, including LPO during ICT compared to baseline values. Connectivity studies in N-back showed significant shifts in linkages after therapy in fronto-parietal regions with a reduction in fractional anisotropy (FA) but not mean diffusivity (MD), and no change in MRS metabolites at the end of the trial. Conclusion A significant improvement in cognition including working memory and inhibitory control, and fractional anisotropy without effect on MD or MRS, through modulation of fronto-parietal and subcortical activation and connectivity was seen after open-label rifaximin therapy in MHE. PMID:24590688

  7. Improvement of storage, handling, and transportability of fine coal. Quarterly technical progress report number 8, October 1--December 31, 1995

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    The Mulled Coal process was developed as a means of overcoming the adverse handling characteristics of wet fine coal without thermal drying. The process involves the addition of a low cost, harmless reagent to wet fine coal using off-the-shelf mixing equipment. Based on laboratory- and bench-scale testing, Mulled coal can be stored, shipped, and burned without causing any of the plugging, pasting, carryback and freezing problems normally associated with wet coal. On the other hand, Mulled Coal does not cause the fugitive and airborne dust problems normally associated with thermally dried coal. The objectives of this project are to demonstratemore » that: the Mulled Coal process, which has been proved to work on a wide range of wet fine coals at bench scale, will work equally well on a continuous basis, producing consistent quality, and at a convincing rate of production in a commercial coal preparation plant; the wet product from a fine coal cleaning circuit can be converted to a solid fuel form for ease of handling and cost savings in storage and rail car transportation; and a wet fine coal product thus converted to a solid fuel form, can be stored, shipped, and burned with conventional fuel handling, transportation, and combustion systems.« less

  8. Personal protective equipment

    MedlinePlus

    ... medlineplus.gov/ency/patientinstructions/000447.htm Personal protective equipment To use the sharing features on this page, please enable JavaScript. Personal protective equipment is special equipment you wear to create a ...

  9. 7 CFR 959.126 - Handling of culls.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Handling of culls. 959.126 Section 959.126 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements...) Handled for canning or freezing. (b) As a safeguard against culls entering fresh market channels each...

  10. Data handling for the modular observatory

    NASA Technical Reports Server (NTRS)

    Taber, J. E.

    1975-01-01

    The current paper summarizes work undertaken at TRW for the EOS satellite and related missions, and it presents conclusions that lead to a flexible and low-cost overall system implementation. It shows how the usual communication and data handling functions must be altered to meet the modularization ground rules, and it demonstrates the modularization that is possible in the handling of wideband payload data both on board and on the ground.

  11. Cooper-Harper Experience Report for Spacecraft Handling Qualities Applications

    NASA Technical Reports Server (NTRS)

    Bailey, Randall E.; Jackson, E. Bruce; Bilimoria, Karl D.; Mueller, Eric R.; Frost, Chad R.; Alderete, Thomas S.

    2009-01-01

    A synopsis of experience from the fixed-wing and rotary-wing aircraft communities in handling qualities development and the use of the Cooper-Harper pilot rating scale is presented as background for spacecraft handling qualities research, development, test, and evaluation (RDT&E). In addition, handling qualities experiences and lessons-learned from previous United States (US) spacecraft developments are reviewed. This report is intended to provide a central location for references, best practices, and lessons-learned to guide current and future spacecraft handling qualities RDT&E.

  12. Cellular Manufacturing System with Dynamic Lot Size Material Handling

    NASA Astrophysics Data System (ADS)

    Khannan, M. S. A.; Maruf, A.; Wangsaputra, R.; Sutrisno, S.; Wibawa, T.

    2016-02-01

    Material Handling take as important role in Cellular Manufacturing System (CMS) design. In several study at CMS design material handling was assumed per pieces or with constant lot size. In real industrial practice, lot size may change during rolling period to cope with demand changes. This study develops CMS Model with Dynamic Lot Size Material Handling. Integer Linear Programming is used to solve the problem. Objective function of this model is minimizing total expected cost consisting machinery depreciation cost, operating costs, inter-cell material handling cost, intra-cell material handling cost, machine relocation costs, setup costs, and production planning cost. This model determines optimum cell formation and optimum lot size. Numerical examples are elaborated in the paper to ilustrate the characterictic of the model.

  13. Common NICU Equipment

    MedlinePlus

    ... care unit (NICU) > Common NICU equipment Common NICU equipment E-mail to a friend Please fill in ... understand how they can help your baby. What equipment is commonly used in the NICU? Providers use ...

  14. Probiotics in management of hepatic encephalopathy.

    PubMed

    Sharma, Barjesh Chander; Singh, Jatinderpal

    2016-12-01

    Gut microflora leads to production of ammonia and endotoxins which play important role in the pathogenesis of hepatic encephalopathy (HE). There is relationship between HE and absorption of nitrogenous substances from the intestines. Probiotics play a role in treatment of HE by causing alterations in gut flora by decreasing the counts of pathogen bacteria, intestinal mucosal acidification, decrease in production and absorption of ammonia, alterations in permeability of gut, decreased endotoxin levels and changes in production of short chain fatty acids. Role of gut microbiota using prebiotics, probiotics and synbiotics have been evaluated in the management of minimal hepatic encephalopathy (MHE), overt HE and prevention of HE. Many studies have shown efficacy of probiotics in reduction of blood ammonia levels, treatment of MHE and prevention of HE. However these trials have problems like inclusion of small number of patients, short treatment durations, variability in HE/MHE related outcomes utilized and high bias risk, errors of systematic and random types. Systematic reviews also have shown different results with one systematic review showing clinical benefits whereas another concluded that probiotics do not have any role in treatment of MHE or HE. Also practical questions on optimal dose, ideal combination of organisms, and duration of treatment and persistence of benefits on long term follow-up are still to be clarified. At present, there are no recommendations for use of probiotics in patients with HE.

  15. 20 CFR 658.421 - Handling of JS-related complaints.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Handling of JS-related complaints. 658.421... ADMINISTRATIVE PROVISIONS GOVERNING THE JOB SERVICE SYSTEM Job Service Complaint System Federal Js Complaint System § 658.421 Handling of JS-related complaints. (a) No JS-related complaint shall be handled at the...

  16. 16 CFR § 1207.10 - Handling, storage, and marking.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Handling, storage, and marking. § 1207.10... REGULATIONS SAFETY STANDARD FOR SWIMMING POOL SLIDES § 1207.10 Handling, storage, and marking. (a) Marking... identification of the manufacturer. (b) Shipping, handling, and storage. The slide shall be designed, constructed...

  17. Handling qualities effects of display latency

    NASA Technical Reports Server (NTRS)

    King, David W.

    1993-01-01

    Display latency is the time delay between aircraft response and the corresponding response of the cockpit displays. Currently, there is no explicit specification for allowable display lags to ensure acceptable aircraft handling qualities in instrument flight conditions. This paper examines the handling qualities effects of display latency between 70 and 400 milliseconds for precision instrument flight tasks of the V-22 Tiltrotor aircraft. Display delay effects on the pilot control loop are analytically predicted through a second order pilot crossover model of the V-22 lateral axis, and handling qualities trends are evaluated through a series of fixed-base piloted simulation tests. The results show that the effects of display latency for flight path tracking tasks are driven by the stability characteristics of the attitude control loop. The data indicate that the loss of control damping due to latency can be simply predicted from knowledge of the aircraft's stability margins, control system lags, and required control bandwidths. Based on the relationship between attitude control damping and handling qualities ratings, latency design guidelines are presented. In addition, this paper presents a design philosophy, supported by simulation data, for using flight director display augmentation to suppress the effects of display latency for delays up to 300 milliseconds.

  18. Alternative Methods for Handling Attrition

    PubMed Central

    Foster, E. Michael; Fang, Grace Y.

    2009-01-01

    Using data from the evaluation of the Fast Track intervention, this article illustrates three methods for handling attrition. Multiple imputation and ignorable maximum likelihood estimation produce estimates that are similar to those based on listwise-deleted data. A panel selection model that allows for selective dropout reveals that highly aggressive boys accumulate in the treatment group over time and produces a larger estimate of treatment effect. In contrast, this model produces a smaller treatment effect for girls. The article's conclusion discusses the strengths and weaknesses of the alternative approaches and outlines ways in which researchers might improve their handling of attrition. PMID:15358906

  19. MHSS: a material handling system simulator

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pomernacki, L.; Hollstien, R.B.

    1976-04-07

    A Material Handling System Simulator (MHSS) program is described that provides specialized functional blocks for modeling and simulation of nuclear material handling systems. Models of nuclear fuel fabrication plants may be built using functional blocks that simulate material receiving, storage, transport, inventory, processing, and shipping operations as well as the control and reporting tasks of operators or on-line computers. Blocks are also provided that allow the user to observe and gather statistical information on the dynamic behavior of simulated plants over single or replicated runs. Although it is currently being developed for the nuclear materials handling application, MHSS can bemore » adapted to other industries in which material accountability is important. In this paper, emphasis is on the simulation methodology of the MHSS program with application to the nuclear material safeguards problem. (auth)« less

  20. 21 CFR 58.107 - Test and control article handling.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Test and control article handling. 58.107 Section... GOOD LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Test and Control Articles § 58.107 Test and control article handling. Procedures shall be established for a system for the handling of the test and...

  1. 21 CFR 58.107 - Test and control article handling.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Test and control article handling. 58.107 Section... GOOD LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Test and Control Articles § 58.107 Test and control article handling. Procedures shall be established for a system for the handling of the test and...

  2. 21 CFR 58.107 - Test and control article handling.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Test and control article handling. 58.107 Section... GOOD LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Test and Control Articles § 58.107 Test and control article handling. Procedures shall be established for a system for the handling of the test and...

  3. 21 CFR 58.107 - Test and control article handling.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Test and control article handling. 58.107 Section... GOOD LABORATORY PRACTICE FOR NONCLINICAL LABORATORY STUDIES Test and Control Articles § 58.107 Test and control article handling. Procedures shall be established for a system for the handling of the test and...

  4. 9 CFR 2.131 - Handling of animals.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false Handling of animals. 2.131 Section 2.131 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Miscellaneous § 2.131 Handling of animals. (a) All licensees who maintain wild...

  5. 9 CFR 2.131 - Handling of animals.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 1 2013-01-01 2013-01-01 false Handling of animals. 2.131 Section 2.131 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Miscellaneous § 2.131 Handling of animals. (a) All licensees who maintain wild...

  6. 9 CFR 2.131 - Handling of animals.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 1 2012-01-01 2012-01-01 false Handling of animals. 2.131 Section 2.131 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Miscellaneous § 2.131 Handling of animals. (a) All licensees who maintain wild...

  7. 9 CFR 2.131 - Handling of animals.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Handling of animals. 2.131 Section 2.131 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE ANIMAL WELFARE REGULATIONS Miscellaneous § 2.131 Handling of animals. (a) All licensees who maintain wild...

  8. Automated processing of forensic casework samples using robotic workstations equipped with nondisposable tips: contamination prevention.

    PubMed

    Frégeau, Chantal J; Lett, C Marc; Elliott, Jim; Yensen, Craig; Fourney, Ron M

    2008-05-01

    An automated process has been developed for the analysis of forensic casework samples using TECAN Genesis RSP 150/8 or Freedom EVO liquid handling workstations equipped exclusively with nondisposable tips. Robot tip cleaning routines have been incorporated strategically within the DNA extraction process as well as at the end of each session. Alternative options were examined for cleaning the tips and different strategies were employed to verify cross-contamination. A 2% sodium hypochlorite wash (1/5th dilution of the 10.8% commercial bleach stock) proved to be the best overall approach for preventing cross-contamination of samples processed using our automated protocol. The bleach wash steps do not adversely impact the short tandem repeat (STR) profiles developed from DNA extracted robotically and allow for major cost savings through the implementation of fixed tips. We have demonstrated that robotic workstations equipped with fixed pipette tips can be used with confidence with properly designed tip washing routines to process casework samples using an adapted magnetic bead extraction protocol.

  9. Handling Qualities Implications for Crewed Spacecraft Operations

    NASA Technical Reports Server (NTRS)

    Bailey, Randall E.; Jackson, E. Bruce; Arthur, J. J.

    2012-01-01

    Abstract Handling qualities embody those qualities or characteristics of an aircraft that govern the ease and precision with which a pilot is able to perform the tasks required in support of an aircraft role. These same qualities are as critical, if not more so, in the operation of spacecraft. A research, development, test, and evaluation process was put into effect to identify, understand, and interpret the engineering and human factors principles which govern the pilot-vehicle dynamic system as they pertain to space exploration missions and tasks. Toward this objective, piloted simulations were conducted at the NASA Langley Research Center and Ames Research Center for earth-orbit proximity operations and docking and lunar landing. These works provide broad guidelines for the design of spacecraft to exhibit excellent handling characteristics. In particular, this work demonstrates how handling qualities include much more than just stability and control characteristics of a spacecraft or aircraft. Handling qualities are affected by all aspects of the pilot-vehicle dynamic system, including the motion, visual and aural cues of the vehicle response as the pilot performs the required operation or task. A holistic approach to spacecraft design, including the use of manual control, automatic control, and pilot intervention/supervision is described. The handling qualities implications of design decisions are demonstrated using these pilot-in-the-loop evaluations of docking operations and lunar landings.

  10. Ergonomic design and evaluation of the handle for an endoscopic dissector.

    PubMed

    Shimomura, Yoshihiro; Minowa, Keita; Kawahira, Hiroshi; Katsuura, Tetsuo

    2016-05-01

    The purpose of this study was to design an endoscopic dissector handle and objectively assess its usability. The handles were designed with increased contact area between the fingers and thumb and the eye rings, and the eye rings were modified to have a more perpendicular insertion angle to the finger midline. Four different handle models were compared, including a conventional product. Subjects performed dissection, exclusion, grasping, precision manipulation and precision handling tasks. Electromyography and subjective evaluations were measured. Compared to conventional handles, the designated handle reduced the muscle load in the extensor and flexor muscles of the forearm and increased subjective stability. The activity of the first dorsal interosseous muscle was sometimes influenced by the shape of the other parts. The ergonomically designed endoscopic dissector handle used in this study achieved high usability. Medical instrument designs based on ergonomic concepts should be assessed with objective indices. Practitioner Summary: The endoscopic dissector handles were designed with increased contact area and more suitable insertion angle between the fingers and thumb and the eye rings. Compared to conventional handles, the designated handle reduced the muscle load in the extensor and flexor muscles of the forearm and increased subjective stability.

  11. Development of EUV mask handling technology at MIRAI-Selete

    NASA Astrophysics Data System (ADS)

    Ota, Kazuya; Amemiya, Mitsuaki; Taguchi, Takao; Kamono, Takashi; Kubo, Hiroyoshi; Takikawa, Tadahiko; Usui, Yoichi; Suga, Osamu

    2007-03-01

    We, MIRAI-Selete, started a new EUV mask program in April, 2006. Development of EUV mask handling technology is one of the key areas of the program. We plan to develop mask handling technology and to evaluate EUV mask carriers using Lasertec M3350, a particle inspection tool with the defect sensitivity less than 50nm PSL, and Mask Protection Engineering Tool (named "MPE Tool"). M3350 is a newly developed tool based on a conventional M1350 for EUV blanks inspection. Since our M3350 has a blank flipping mechanism in it, we can inspect the front and the back surface of the blank automatically. We plan to use the M3350 for evaluating particle adders during mask shipping, storage and handling. MPE Tool is a special tool exclusively developed for demonstration of pellicleless mask handling. It can handle a mask within a protective enclosure, which Canon and Nikon have been jointly proposing1, and also, can be modified to handle other type of carrier as the need arises.

  12. 45 CFR 650.19 - Electronic invention handling.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 3 2011-10-01 2011-10-01 false Electronic invention handling. 650.19 Section 650.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION PATENTS § 650.19 Electronic invention handling. (a) Grantees must use the iEdison Invention Information Management System maintained by the National...

  13. 45 CFR 650.19 - Electronic invention handling.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 3 2014-10-01 2014-10-01 false Electronic invention handling. 650.19 Section 650.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION PATENTS § 650.19 Electronic invention handling. (a) Grantees must use the iEdison Invention Information Management System maintained by the National...

  14. 45 CFR 650.19 - Electronic invention handling.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 3 2013-10-01 2013-10-01 false Electronic invention handling. 650.19 Section 650.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION PATENTS § 650.19 Electronic invention handling. (a) Grantees must use the iEdison Invention Information Management System maintained by the National...

  15. 45 CFR 650.19 - Electronic invention handling.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Electronic invention handling. 650.19 Section 650.19 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION PATENTS § 650.19 Electronic invention handling. (a) Grantees must use the iEdison Invention Information Management System maintained by the National...

  16. Space processing applications payload equipment study. Volume 2E: Commercial equipment utility

    NASA Technical Reports Server (NTRS)

    Smith, A. G. (Editor)

    1974-01-01

    Examination of commercial equipment technologies revealed that the functional performance requirements of space processing equipment could generally be met by state-of-the-art design practices. Thus, an apparatus could be evolved from a standard item or derived by custom design using present technologies. About 15 percent of the equipment needed has no analogous commercial base of derivation and requires special development. This equipment is involved primarily with contactless heating and position control. The derivation of payloads using commercial equipment sources provides a broad and potentially cost-effective base upon which to draw. The derivation of payload equipment from commercial technologies poses other issues beyond that of the identifiable functional performance, but preliminary results on testing of selected equipment testing appear quite favorable. During this phase of the SPA study, several aspects of commercial equipment utility were assessed and considered. These included safety, packaging and structural, power conditioning (electrical/electronic), thermal and materials of construction.

  17. Evaluating performance of containment equipment designed for handling manufactured nanomaterials by use of nanoparticle tracer

    NASA Astrophysics Data System (ADS)

    Artous, Sébastien; Bombardier, Pierre; Derrough, Samir; Locatelli, Dominique; Nobile, Pierre; Durand, Catherine

    2013-04-01

    The implementation in many products of manufactured nanoparticles is in strong growth and raises new questions. For this purpose, the CEA - NanoSafety Platform is developing various research topics for health and safety, environment and nanoparticles exposure in professional activities. The working group Nano-CERT/MTD, driven by INERIS, federates actors of the sector: experts, research organizations, industrial users and manufacturers of collective protection. The main activity of this group is to establish specific guidelines or a voluntary certification of collective protection, at a national scale, but with the possibility of a further extension at an European level. The group aims to establish an experimental protocol of certification to characterize collective protections for workers faced with nanomaterials potential exposure. The NanoSafety Platform provides in this presentation a method of collective protection characterization based on the developments in nanoparticles metrology and on the study of existing standards and practices in related areas (chemicals, dust, microbiological and nuclear). This study presents the results obtained during the experimental characterization of a potential nanoparticles transfer in a prototype laboratory fume hood by the use of a particulate tracer of sodium-fluorescein. The efficiency of the equipment and more specifically the efficiency of dynamical air barrier is evaluated, with the experimental results, by calculating the backward diffusion coefficient.

  18. Orion Entry Handling Qualities Assessments

    NASA Technical Reports Server (NTRS)

    Bihari, B.; Tiggers, M.; Strahan, A.; Gonzalez, R.; Sullivan, K.; Stephens, J. P.; Hart, J.; Law, H., III; Bilimoria, K.; Bailey, R.

    2011-01-01

    The Orion Command Module (CM) is a capsule designed to bring crew back from the International Space Station (ISS), the moon and beyond. The atmospheric entry portion of the flight is deigned to be flown in autopilot mode for nominal situations. However, there exists the possibility for the crew to take over manual control in off-nominal situations. In these instances, the spacecraft must meet specific handling qualities criteria. To address these criteria two separate assessments of the Orion CM s entry Handling Qualities (HQ) were conducted at NASA s Johnson Space Center (JSC) using the Cooper-Harper scale (Cooper & Harper, 1969). These assessments were conducted in the summers of 2008 and 2010 using the Advanced NASA Technology Architecture for Exploration Studies (ANTARES) six degree of freedom, high fidelity Guidance, Navigation, and Control (GN&C) simulation. This paper will address the specifics of the handling qualities criteria, the vehicle configuration, the scenarios flown, the simulation background and setup, crew interfaces and displays, piloting techniques, ratings and crew comments, pre- and post-fight briefings, lessons learned and changes made to improve the overall system performance. The data collection tools, methods, data reduction and output reports will also be discussed. The objective of the 2008 entry HQ assessment was to evaluate the handling qualities of the CM during a lunar skip return. A lunar skip entry case was selected because it was considered the most demanding of all bank control scenarios. Even though skip entry is not planned to be flown manually, it was hypothesized that if a pilot could fly the harder skip entry case, then they could also fly a simpler loads managed or ballistic (constant bank rate command) entry scenario. In addition, with the evaluation set-up of multiple tasks within the entry case, handling qualities ratings collected in the evaluation could be used to assess other scenarios such as the constant bank angle

  19. 33 CFR 126.33 - Penalties for handling dangerous cargo without permit.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Penalties for handling dangerous... HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.33 Penalties for handling dangerous cargo without permit. Handling, storing, stowing, loading...

  20. 33 CFR 126.33 - Penalties for handling dangerous cargo without permit.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Penalties for handling dangerous... HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.33 Penalties for handling dangerous cargo without permit. Handling, storing, stowing, loading...

  1. 33 CFR 126.33 - Penalties for handling dangerous cargo without permit.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Penalties for handling dangerous... HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.33 Penalties for handling dangerous cargo without permit. Handling, storing, stowing, loading...

  2. 33 CFR 126.33 - Penalties for handling dangerous cargo without permit.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Penalties for handling dangerous... HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.33 Penalties for handling dangerous cargo without permit. Handling, storing, stowing, loading...

  3. 33 CFR 126.33 - Penalties for handling dangerous cargo without permit.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Penalties for handling dangerous... HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.33 Penalties for handling dangerous cargo without permit. Handling, storing, stowing, loading...

  4. Musculoskeletal injuries among hospital patient care staff before and after implementation of patient lift and transfer equipment.

    PubMed

    Schoenfisch, Ashley L; Lipscomb, Hester J; Pompeii, Lisa A; Myers, Douglas J; Dement, John M

    2013-01-01

    Using an observational research design and robust surveillance data, we evaluated rates of musculoskeletal (MS) injuries, days away from work, and restricted work days among patient care staff at a medical center and community hospital in the United States over 13 years, during which time a "minimal manual lift" policy and mechanical lift equipment were implemented. Workers' compensation claims data were linked to human resources data to define outcomes of interest and person-time at risk to calculate rates. Poisson and negative binomial regression with lagging were used to compare outcome rates in different windows of time surrounding the intervention. Patterns of MS injuries associated with patient-handling were contrasted to patterns of other MS injuries that would not be affected by the use of mechanical lift equipment. At the medical center, no change in the patient-handling MS injury rate followed the intervention. A 44% decrease was observed at the community hospital. At both hospitals, the rate of days away declined immediately - before it was reasonable for the intervention to have been adopted. Institutional-level changes at the time of the intervention likely influenced observed results with findings only partially consistent with an intervention effect. Observational studies can be useful in assessing effectiveness of safety interventions in complex work environments. Such studies should consider the process of intervention implementation, the time needed for intervention adoption, and the dynamic nature of work environments.

  5. Cleaning supplies and equipment

    MedlinePlus

    ... gov/ency/patientinstructions/000443.htm Cleaning supplies and equipment To use the sharing features on this page, ... to clean supplies and equipment. Disinfecting Supplies and Equipment Start by wearing the right personal protective equipment ( ...

  6. Enteral Feeding Set Handling Techniques.

    PubMed

    Lyman, Beth; Williams, Maria; Sollazzo, Janet; Hayden, Ashley; Hensley, Pam; Dai, Hongying; Roberts, Cristine

    2017-04-01

    Enteral nutrition therapy is common practice in pediatric clinical settings. Often patients will receive a pump-assisted bolus feeding over 30 minutes several times per day using the same enteral feeding set (EFS). This study aims to determine the safest and most efficacious way to handle the EFS between feedings. Three EFS handling techniques were compared through simulation for bacterial growth, nursing time, and supply costs: (1) rinsing the EFS with sterile water after each feeding, (2) refrigerating the EFS between feedings, and (3) using a ready-to-hang (RTH) product maintained at room temperature. Cultures were obtained at baseline, hour 12, and hour 21 of the 24-hour cycle. A time-in-motion analysis was conducted and reported in average number of seconds to complete each procedure. Supply costs were inventoried for 1 month comparing the actual usage to our estimated usage. Of 1080 cultures obtained, the overall bacterial growth rate was 8.7%. The rinse and refrigeration techniques displayed similar bacterial growth (11.4% vs 10.3%, P = .63). The RTH technique displayed the least bacterial growth of any method (4.4%, P = .002). The time analysis in minutes showed the rinse method was the most time-consuming (44.8 ± 2.7) vs refrigeration (35.8 ± 2.6) and RTH (31.08 ± 0.6) ( P < .0001). All 3 EFS handling techniques displayed low bacterial growth. RTH was superior in bacterial growth, nursing time, and supply costs. Since not all pediatric formulas are available in RTH, we conclude that refrigerating the EFS between uses is the next most efficacious method for handling the EFS between bolus feeds.

  7. US Department of Energy's Efforts in Intelligent Processing Equipment

    NASA Technical Reports Server (NTRS)

    Peavy, Richard D.; Mcfarland, Janet C.

    1992-01-01

    The Department of Energy (DOE) uses intelligent processing equipment (IPE) technologies to conduct research and development and manufacturing for energy and nuclear weapons programs. This paper highlights several significant IPE efforts underway in DOE. IPE technologies are essential to the accomplishment of DOE's missions, because of the need for small lot production, precision, and accuracy in manufacturing, hazardous waste management, and protection of the environment and the safety and health of the workforce and public. Applications of IPE technologies include environmental remediation and waste handling, advanced manufacturing, and automation of tasks carried out in hazardous areas. DOE laboratories have several key programs that integrate robotics, sensor, and control technologies. These programs embody a considerable technical capability that also may be used to enhance U.S. industrial competitiveness. DOE encourages closer cooperation with U.S. industrial partners based on mutual benefits. This paper briefly describes technology transfer mechanisms available for industrial involvement.

  8. How the NWC handles software as product

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vinson, D.

    1997-11-01

    This tutorial provides a hands-on view of how the Nuclear Weapons Complex project should be handling (or planning to handle) software as a product in response to Engineering Procedure 401099. The SQAS has published the document SQAS96-002, Guidelines for NWC Processes for Handling Software Product, that will be the basis for the tutorial. The primary scope of the tutorial is on software products that result from weapons and weapons-related projects, although the information presented is applicable to many software projects. Processes that involve the exchange, review, or evaluation of software product between or among NWC sites, DOE, and external customersmore » will be described.« less

  9. Neonatal handling reduces renal function in adult rats.

    PubMed

    Donadio, Márcio Vinícius Fagundes; Jacobs, Silvana; Corezola, Kizzy Ludnila; Melo, Denizar Alberto da Silva; Dias, Henrique Bregolin; Reichel, Carlos Luiz; Franci, Celso Rodrigues; Jeckel-Neto, Emilio Antonio; Lulhier, Francisco; Lucion, Aldo Bolten; de Oliveira, Jarbas Rodrigues; Sanvitto, Gilberto Luiz

    2009-01-01

    To evaluate the effects of neonatal handling on hydroelectrolytic balance in adult rats. The litters were divided into two groups: nonhandled and handled. The procedure consisted of handling the pups for 1 min/day in the first 10 days postnatally. When adults, animals had their body weight verified and were housed in individual metabolic cages. After a 24-hour period, urine samples were collected and the urinary and water intake volumes measured. Blood samples to determine osmolality, aldosterone, corticosterone, angiotensin II, creatinine, urea, sodium and potassium levels were collected. The kidneys were removed for histological assessment. Urinary osmolality, sodium, urea and creatinine were also measured and the creatinine clearance (CC) calculated. No difference between groups was found in the body weight. Handled animals showed a reduction in the total kidney wet weight, water intake, urinary volume, CC, plasma angiotensin II, corticosterone and aldosterone when compared to the nonhandled and an increase in the urinary osmolality and sodium excretion fraction. No differences in serum potassium and no evidence of structural changes were demonstrated by histological analysis. Neonatal handling induced long-lasting effects decreasing renal function without evidence of kidney structural changes. (c) 2009 S. Karger AG, Basel.

  10. Weight-Handling Equipment. Design Manual 38.1.

    DTIC Science & Technology

    1982-06-01

    Contact Rails ....... ................... 38.1-153 B-1. Torque-Speed Curves of Wound- Rotor Motor with Single-Phase Dynamic Braking Control...38.1-B-4 B-2. Torque-Speed Curves for Wound- Rotor Motor with DC Dynamic -Braking Lowering Control ... ........... . 38.1-B-6 B-3. Torque-Speed Curves...AC hoist and DC dynamic -braking lowering). (b) Wound- rotor motors. (i) Heavy-duty cranes using AC motors should have motors of the wound- rotor (slip

  11. Material Handling Equipment Evaluation for Crater Repair

    DTIC Science & Technology

    2016-11-01

    Department of the Army position unless so designated by other authorized documents. DESTROY THIS REPORT WHEN NO LONGER NEEDED. DO NOT RETURN IT TO THE...project. Jeb. S. Tingle was the ERDC Airfield Damage Repair program manager. The work was performed by the Airfields and Pavement Branch (GMA) of the...USAF’s) ability to perform airfield pavement repair tasks to support the operation of modern aircraft for a variety of mission scenarios. The ADR

  12. Orion Handling Qualities During ISS Proximity Operations and Docking

    NASA Technical Reports Server (NTRS)

    Stephens, John-Paul; Vos, Gordon A.; Bilimoria, Karl D.; Mueller, Eric R.; Brazzel, Jack; Spehar, Pete

    2011-01-01

    NASA's Orion spacecraft is designed to autonomously rendezvous and dock with many vehicles including the International Space Station. However, the crew is able to assume manual control of the vehicle s attitude and flight path. In these instances, Orion must meet handling qualities requirements established by NASA. Two handling qualities assessments were conducted at the Johnson Space Center to evaluate preliminary designs of the vehicle using a six degree of freedom, high-fidelity guidance, navigation, and control simulation. The first assessed Orion s handling qualities during the last 20 ft before docking, and included both steady and oscillatory motions of the docking target. The second focused on manual acquisition of the docking axis during the proximity operations phase and subsequent station-keeping. Cooper-Harper handling qualities ratings, workload ratings and comments were provided by 10 evaluation pilots for the docking study and 5 evaluation pilots for the proximity operations study. For the docking task, both cases received 90% Level 1 (satisfactory) handling qualities ratings, exceeding NASA s requirement. All ratings for the ProxOps task were Level 1. These evaluations indicate that Orion is on course to meet NASA's handling quality requirements for ProxOps and docking.

  13. Lifting and exertion injuries decrease after implementation of an integrated hospital-wide safe patient handling and mobilisation programme.

    PubMed

    Dennerlein, Jack T; O'Day, Elizabeth Tucker; Mulloy, Deborah F; Somerville, Jackie; Stoddard, Anne M; Kenwood, Christopher; Teeple, Erin; Boden, Leslie I; Sorensen, Glorian; Hashimoto, Dean

    2017-05-01

    With increasing emphasis on early and frequent mobilisation of patients in acute care, safe patient handling and mobilisation practices need to be integrated into these quality initiatives. We completed a programme evaluation of a safe patient handling and mobilisation programme within the context of a hospital-wide patient care improvement initiative that utilised a systems approach and integrated safe patient equipment and practices into patient care plans. Baseline and 12-month follow-up surveys of 1832 direct patient care workers assessed work practices and self-reported pain while an integrated employee payroll and injury database provided recordable injury rates collected concurrently at 2 hospitals: the study hospital with the programme and a comparison hospital. Safe and unsafe patient handling practice scales at the study hospital improved significantly (p<0.0001 and p=0.0031, respectively), with no differences observed at the comparison hospital. We observed significant decreases in recordable neck and shoulder (Relative Risk (RR)=0.68, 95% CI 0.46 to 1.00), lifting and exertion (RR=0.73, 95% CI 0.60 to 0.89) and pain and inflammation (RR=0.78, 95% CI 0.62 to 1.00) injury rates at the study hospital. Changes in rates at the comparison hospital were not statistically significant. Within the context of a patient mobilisation initiative, a safe patient handling and mobilisation programme was associated with improved work practices and a reduction in recordable worker injuries. This study demonstrates the potential impact of utilising a systems approach based on recommended best practices, including integration of these practices into the patient's plan for care. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  14. MVAPACK: A Complete Data Handling Package for NMR Metabolomics

    PubMed Central

    2015-01-01

    Data handling in the field of NMR metabolomics has historically been reliant on either in-house mathematical routines or long chains of expensive commercial software. Thus, while the relatively simple biochemical protocols of metabolomics maintain a low barrier to entry, new practitioners of metabolomics experiments are forced to either purchase expensive software packages or craft their own data handling solutions from scratch. This inevitably complicates the standardization and communication of data handling protocols in the field. We report a newly developed open-source platform for complete NMR metabolomics data handling, MVAPACK, and describe its application on an example metabolic fingerprinting data set. PMID:24576144

  15. 7 CFR 1924.259 - Handling dwelling construction complaints.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Handling dwelling construction complaints. 1924.259... OF AGRICULTURE PROGRAM REGULATIONS CONSTRUCTION AND REPAIR Complaints and Compensation for Construction Defects § 1924.259 Handling dwelling construction complaints. This section describes the procedure...

  16. A comparative life cycle assessment of material handling systems for sustainable mining.

    PubMed

    Erkayaoğlu, M; Demirel, N

    2016-06-01

    In this comprehensive LCA comparison study, main objectives are to investigate life cycle environmental impacts of off-highway mining trucks and belt conveyors in surface mining. The research methodology essentially entails determination of the functional unit as 20,000 tons/day coal production transported for 5 km distance. After the system boundary was selected as the entire life cycle of material handling systems including pre-manufacturing of steel parts and plastic components, manufacturing, transportation, and utilization data was compiled from equipment manufacturers and the Eco-invent database. Life cycle impact categories for both material-handling systems were identified and the developed model was implemented using SIMAPRO 7.3. Climate change and acidification were selected as major impact categories as they were considered to be major concerns in mining industry. Although manufacturing stage had a significant impact on all of the environmental parameters, utilization stage was the hotspot for the selected impact categories. The results of this study revealed that belt conveyors have a greater environmental burden in climate change impact category when compared to the trucks. On the other hand, trucks have a greater environmental burden in acidification impact category when compared to the belt conveyors. This study implied that technological improvement in fuel combustion and electricity generation is crucial for the improvement of environmental profiles of off-highway trucks and belt conveyors in the mining industry. The main novelty of this study is that it is the first initiative in applying LCA in the Turkish mining industry. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Renewal of radiological equipment.

    PubMed

    2014-10-01

    In this century, medical imaging is at the heart of medical practice. Besides providing fast and accurate diagnosis, advances in radiology equipment offer new and previously non-existing options for treatment guidance with quite low morbidity, resulting in the improvement of health outcomes and quality of life for the patients. Although rapid technological development created new medical imaging modalities and methods, the same progress speed resulted in accelerated technical and functional obsolescence of the same medical imaging equipment, consequently creating a need for renewal. Older equipment has a high risk of failures and breakdowns, which might cause delays in diagnosis and treatment of the patient, and safety problems both for the patient and the medical staff. The European Society of Radiology is promoting the use of up-to-date equipment, especially in the context of the EuroSafe Imaging Campaign, as the use of up-to-date equipment will improve quality and safety in medical imaging. Every healthcare institution or authority should have a plan for medical imaging equipment upgrade or renewal. This plan should look forward a minimum of 5 years, with annual updates. Teaching points • Radiological equipment has a definite life cycle span, resulting in unavoidable breakdown and decrease or loss of image quality which renders equipment useless after a certain time period.• Equipment older than 10 years is no longer state-of-the art equipment and replacement is essential. Operating costs of older equipment will be high when compared with new equipment, and sometimes maintenance will be impossible if no spare parts are available.• Older equipment has a high risk of failure and breakdown, causing delays in diagnosis and treatment of the patient and safety problems both for the patient and the medical staff.• Every healthcare institution or authority should have a plan for medical imaging equipment upgrade or replacement. This plan should look forward a

  18. TDRSS data handling and management system study. Ground station systems for data handling and relay satellite control

    NASA Technical Reports Server (NTRS)

    1973-01-01

    Results of a two-phase study of the (Data Handling and Management System DHMS) are presented. An original baseline DHMS is described. Its estimated costs are presented in detail. The DHMS automates the Tracking and Data Relay Satellite System (TDRSS) ground station's functions and handles both the forward and return link user and relay satellite data passing through the station. Direction of the DHMS is effected via a TDRSS Operations Control Central (OCC) that is remotely located. A composite ground station system, a modified DHMS (MDHMS), was conceptually developed. The MDHMS performs both the DHMS and OCC functions. Configurations and costs are presented for systems using minicomputers and midicomputers. It is concluded that a MDHMS should be configured with a combination of the two computer types. The midicomputers provide the system's organizational direction and computational power, and the minicomputers (or interface processors) perform repetitive data handling functions that relieve the midicomputers of these burdensome tasks.

  19. Do Mice Habituate to “Gentle Handling?” A Comparison of Resting Behavior, Corticosterone Levels and Synaptic Function in Handled and Undisturbed C57BL/6J Mice

    PubMed Central

    Longordo, Fabio; Fan, Jing; Steimer, Thierry; Kopp, Caroline; Lüthi, Anita

    2011-01-01

    Study Objectives: “Gentle handling” has become a method of choice for 4-6 h sleep deprivation in mice, with repeated brief handling applied before sleep deprivation to induce habituation. To verify whether mice do indeed habituate, we assess how 6 days of repeated brief handling impact on resting behavior, on stress, and on the subunit content of N-methyl-D-aspartate receptors (NMDARs) at hippocampal synapses, which is altered by sleep loss. We discuss whether repeated handling biases the outcome of subsequent sleep deprivation. Design: Adult C57BL/6J mice, maintained on a 12 h-12 h light-dark cycle, were left undisturbed for 3 days, then handled during 3 min daily for 6 days in the middle of the light phase. Mice were continuously monitored for their resting time. Serum corticosterone levels and synaptic NMDAR subunit composition were quantified. Results: Handling caused a ∼25% reduction of resting time throughout all handling days. After six, but not after one day of handling, mice had elevated serum corticosterone levels. Six-day handling augmented the presence of the NR2A subunit of NMDARs at hippocampal synapses. Conclusion: Repeated handling induces behavioral and neurochemical alterations that are absent in undisturbed animals. The persistently reduced resting time and the delayed increase in corticosterone levels indicate that mice do not habituate to handling over a 1-week period. Handling-induced modifications bias effects of gentle handling-induced sleep deprivation on sleep homeostasis, stress, glutamate receptor composition and signaling. A standardization of sleep deprivation procedures involving gentle handling will be important for unequivocally specifying how acute sleep loss affects brain function. Citation: Longordo F; Fan J; Steimer T; Kopp C; Lüthi A. Do mice habituate to “gentle handling?” A comparison of resting behavior, corticosterone levels and synaptic function in handled and undisturbed C57BL/6J mice. SLEEP 2011

  20. Oncology pharmacy units: a safety policy for handling hazardous drugs and related waste in low- and middle-income African countries-Angolan experience.

    PubMed

    da Conceição, Ana Vaz; Bernardo, Dora; Lopes, Lygia Vieira; Miguel, Fernando; Bessa, Fernanda; Monteiro, Fernando; Santos, Cristina; Oliveira, Blasques; Santos, Lúcio Lara

    2015-01-01

    In African countries, higher rates of late-stage cancers at the time of first diagnosis are a reality. In this context, hazardous drugs (HDs), such as chemotherapy, play an important role and have immense benefits for patients' treatment. HDs should be handled under specific conditions. At least a class 5 environment primary engineering control (PEC), physically located in an appropriate buffer area, is mandatory for sterile HDs compounding, as well as administrative control, personal protective equipment, work practices and other engineering and environmental controls, in order to protect the environment, patient, and worker. The aim of this study is to describe the Angolan experience regarding the development of oncology pharmacy units and discuss international evidence-based guidelines on handling HDs and related waste. Measures to incorporate modern and economical solutions to upgrade or build adequate and safe facilities and staff training, in order to comply with international guidelines in this area, are crucial tasks for African countries of low and middle income.

  1. 33 CFR 126.27 - General permit for handling dangerous cargo.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... dangerous cargo. 126.27 Section 126.27 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.27 General permit for handling dangerous cargo. A general permit is hereby issued for the handling, storing...

  2. 33 CFR 126.27 - General permit for handling dangerous cargo.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... dangerous cargo. 126.27 Section 126.27 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.27 General permit for handling dangerous cargo. A general permit is hereby issued for the handling, storing...

  3. 33 CFR 126.27 - General permit for handling dangerous cargo.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... dangerous cargo. 126.27 Section 126.27 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.27 General permit for handling dangerous cargo. A general permit is hereby issued for the handling, storing...

  4. 33 CFR 126.27 - General permit for handling dangerous cargo.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... dangerous cargo. 126.27 Section 126.27 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) WATERFRONT FACILITIES HANDLING OF DANGEROUS CARGO AT WATERFRONT FACILITIES § 126.27 General permit for handling dangerous cargo. A general permit is hereby issued for the handling, storing...

  5. Mars Sample Handling Functionality

    NASA Astrophysics Data System (ADS)

    Meyer, M. A.; Mattingly, R. L.

    2018-04-01

    The final leg of a Mars Sample Return campaign would be an entity that we have referred to as Mars Returned Sample Handling (MRSH.) This talk will address our current view of the functional requirements on MRSH, focused on the Sample Receiving Facility (SRF).

  6. SpaceFibre: The Standard, Simulation, IP Cores and Test Equipment

    NASA Astrophysics Data System (ADS)

    Parkes, Steve; McClements, Chris; McLaren, David; Ferrer Florit, Albert; Gonzalez Villafranca, Alberto

    2015-09-01

    SpaceFibre is an emerging new standard for spacecraft on-board data-handling networks. Initially targeted to deliver multi-Gbit/s data rates for synthetic aperture radar and high-resolution, multi-spectral imaging instruments, SpaceFibre has developed into a unified network technology that integrates high bandwidth, with low latency, quality of service (QoS) and fault detection, isolation and recovery (FDIR). Furthermore SpaceFibre is backwards compatible with the widely used SpaceWire standard at the network level allowing simple interconnection of existing SpaceWire equipment to a SpaceFibre link or network. Developed by the University of Dundee for the European Space Agency (ESA) SpaceFibre is able to operate over fibre-optic and electrical cable and supports data rates of 2 Gbit/s in the near future and up to 5 Gbit/s long-term. Multi-laning improves the data-rate further to well over 20 Gbits/s. This paper details the current state of SpaceFibre which is now in the process of formal standardisation by the European Cooperation for Space Standardization (ECSS). It describes the SpaceFibre IP core being developed for ESA. The design of a SpaceFibre demonstration board is introduced and available SpaceFibre test and development equipment is described. The way in which several SpaceWire links can be concentrated over a single SpaceFibre link will be explained.

  7. Planetary sample rapid recovery and handling

    NASA Technical Reports Server (NTRS)

    1985-01-01

    Methods for recovering and cost effectively handling planetary samples following return to the vicinity of Earth were designed for planetary mission planners. Three topics are addressed: (1) a rough cost estimate was produced for each of a series of options for the handling of planetary samples following their return to the vicinity of Earth; (2) the difficulty of quickly retrieving planetary samples from low circular and high elliptical Earth orbit is assessed; and (3) a conceptual design for a biological isolation and thermal control system for the returned sample and spacecraft is developed.

  8. Adherence to Safe Handling Guidelines by Health Care Workers Who Administer Antineoplastic Drugs

    PubMed Central

    Boiano, James M.; Steege, Andrea L.; Sweeney, Marie H.

    2015-01-01

    The toxicity of antineoplastic drugs is well documented. Many are known or suspected human carcinogens where no safe exposure level exists. Authoritative guidelines developed by professional practice organizations and federal agencies for the safe handling of these hazardous drugs have been available for nearly three decades. As a means of evaluating the extent of use of primary prevention practices such as engineering, administrative and work practice controls, personal protective equipment (PPE), and barriers to using PPE, the National Institute for Safety and Health (NIOSH) conducted a web survey of health care workers in 2011. The study population primarily included members of professional practice organizations representing health care occupations which routinely use or come in contact with selected chemical agents. All respondents who indicated that they administered antineoplastic drugs in the past week were eligible to complete a hazard module addressing self-reported health and safety practices on this topic. Most (98%) of the 2069 respondents of this module were nurses. Working primarily in hospitals, outpatient care centers, and physician offices, respondents reported that they had collectively administered over 90 specific antineoplastic drugs in the past week, with carboplatin, cyclophosphamide, and paclitaxel the most common. Examples of activities which increase exposure risk, expressed as percent of respondents, included: failure to wear nonabsorbent gown with closed front and tight cuffs (42%); intravenous (I.V.) tubing primed with antineoplastic drug by respondent (6%) or by pharmacy (12%); potentially contaminated clothing taken home (12%); spill or leak of antineoplastic drug during administration (12%); failure to wear chemotherapy gloves (12%); and lack of hazard awareness training (4%). The most common reason for not wearing gloves or gowns was “skin exposure was minimal”; 4% of respondents, however, reported skin contact during handling

  9. Air-Cooled Stack Freeze Tolerance Freeze Failure Modes and Freeze Tolerance Strategies for GenDriveTM Material Handling Application Systems and Stacks Final Scientific Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hancock, David, W.

    2012-02-14

    Air-cooled stack technology offers the potential for a simpler system architecture (versus liquid-cooled) for applications below 4 kilowatts. The combined cooling and cathode air allows for a reduction in part count and hence a lower cost solution. However, efficient heat rejection challenges escalate as power and ambient temperature increase. For applications in ambient temperatures below freezing, the air-cooled approach has additional challenges associated with not overcooling the fuel cell stack. The focus of this project was freeze tolerance while maintaining all other stack and system requirements. Through this project, Plug Power advanced the state of the art in technology formore » air-cooled PEM fuel cell stacks and related GenDrive material handling application fuel cell systems. This was accomplished through a collaborative work plan to improve freeze tolerance and mitigate freeze-thaw effect failure modes within innovative material handling equipment fuel cell systems designed for use in freezer forklift applications. Freeze tolerance remains an area where additional research and understanding can help fuel cells to become commercially viable. This project evaluated both stack level and system level solutions to improve fuel cell stack freeze tolerance. At this time, the most cost effective solutions are at the system level. The freeze mitigation strategies developed over the course of this project could be used to drive fuel cell commercialization. The fuel cell system studied in this project was Plug Power's commercially available GenDrive platform providing battery replacement for equipment in the material handling industry. The fuel cell stacks were Ballard's commercially available FCvelocity 9SSL (9SSL) liquid-cooled PEM fuel cell stack and FCvelocity 1020ACS (Mk1020) air-cooled PEM fuel cell stack.« less

  10. Handling and Shipping. ERIC Processing Manual, Section IV.

    ERIC Educational Resources Information Center

    Brandhorst, Ted, Ed.; And Others

    Rules and guidelines are provided for the handling and shipping of document and journal article information intended for announcement in ERIC's abstract journals "Resources in Education" and "Current Index to Journals in Education." The handling and shipping involved takes place between the ERIC Facility and the ERIC…

  11. Teaching Data Handling in Foundation Phase: Teachers' Experiences

    ERIC Educational Resources Information Center

    Naidoo, Jayaluxmi; Mkhabela, Nokuphiwa

    2017-01-01

    Data handling plays an important role within mathematics education since it encompasses real-world situations and assists in developing critical thinking skills in learners. However, globally international assessments disclose that learners are not performing well in data handling. This article explores foundation phase South African teachers'…

  12. Maternal handling during pregnancy reduces DMBA-induced mammary tumorigenesis among female offspring.

    PubMed Central

    Hilakivi-Clarke, L.

    1997-01-01

    The present study investigated whether handling of pregnant rats would affect mammary tumorigenesis in their female offspring. Pregnant Sprague-Dawley rats were injected daily with 0.05 ml of vehicle between days 14 and 20 of gestation or were left undisturbed. Handling did not have any effects on pregnancy or early development of the offspring. The female offspring were administered 10 mg of 7,12-dimethylbenz(a)anthracene (DMBA) at the age of 55 days. The rats whose mothers were handled during pregnancy had a significantly reduced mammary tumour incidence when compared with the offspring of non-handled mothers. Thus, on week 18 after DMBA exposure, 15% of the handled offspring had developed mammary tumours, whereas 44% of the non-handled offspring had tumours. No significant differences in the latency to tumour appearance, in the size of the tumours or in their growth rates were noted. Daily handling performed during post-natal days 5 and 20 produced similar data to that obtained for prenatal handling; on week 18 after DMBA exposure, the mammary tumour incidence among the post-natally handled rats was 22% and among the non-handled rats 44%. Possible deviations in hormonal parameters were also studied in adult female rats exposed in utero to handling. The onset of puberty tended to occur later among the handled offspring, but no differences in the uterine wet weights or serum oestradiol levels between the groups were noted. In conclusion, maternal handling reduced the offspring's risk to develop mammary tumours, and this effect was independent of the oestrogenic environment at adulthood. We propose that handling of a pregnant rat reduces mammary tumorigenesis in her offspring by means of changing the morphology of the mammary gland, the pattern of expression of specific genes and/or immune functions. PMID:9231913

  13. Combination sound and vibration isolation curb for rooftop air-handling systems

    NASA Astrophysics Data System (ADS)

    Paige, Thomas S.

    2005-09-01

    This paper introduces the new Model ESSR Sound and Vibration Isolation Curb manufactured by Kinetics Noise Control, Inc. This product was specially designed to address all of the common transmission paths associated with noise and vibration sources from roof-mounted air-handling equipment. These include: reduction of airborne fan noise in supply and return air ductwork, reduction of duct rumble and breakout noise, reduction of direct airborne sound transmission through the roof deck, and reduction of vibration and structure-borne noise transmission to the building structure. Upgrade options are available for increased seismic restraint and wind-load protection. The advantages of this new system over the conventional approach of installing separate duct silencers in the room ceiling space below the rooftop unit are discussed. Several case studies are presented with the emphasis on completed projects pertaining to classrooms and school auditorium applications. Some success has also been achieved by adding active noise control components to improve low-frequency attenuation. This is an innovative product designed for conformance with the new classroom acoustics standard ANSI S12.60.

  14. 46 CFR 151.25-2 - Cargo handling space.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Cargo handling space. 151.25-2 Section 151.25-2 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Environmental Control § 151.25-2 Cargo handling space. Pump rooms, compressor rooms, refrigeration rooms, heating rooms, instrument rooms or other closed spaces...

  15. 46 CFR 151.25-2 - Cargo handling space.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Cargo handling space. 151.25-2 Section 151.25-2 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Environmental Control § 151.25-2 Cargo handling space. Pump rooms, compressor rooms, refrigeration rooms, heating rooms, instrument rooms or other closed spaces...

  16. 46 CFR 151.25-2 - Cargo handling space.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Cargo handling space. 151.25-2 Section 151.25-2 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Environmental Control § 151.25-2 Cargo handling space. Pump rooms, compressor rooms, refrigeration rooms, heating rooms, instrument rooms or other closed spaces...

  17. 46 CFR 151.25-2 - Cargo handling space.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Cargo handling space. 151.25-2 Section 151.25-2 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Environmental Control § 151.25-2 Cargo handling space. Pump rooms, compressor rooms, refrigeration rooms, heating rooms, instrument rooms or other closed spaces...

  18. 46 CFR 151.25-2 - Cargo handling space.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Cargo handling space. 151.25-2 Section 151.25-2 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Environmental Control § 151.25-2 Cargo handling space. Pump rooms, compressor rooms, refrigeration rooms, heating rooms, instrument rooms or other closed spaces...

  19. 19 CFR 151.29 - Expense of unlading and handling.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Molasses § 151.29 Expense of unlading and handling. No expense incidental to the unlading, transporting, or handling of sugar, sirup, or molasses for convenient weighing, gaging, measuring, sampling, or marking...

  20. 19 CFR 151.29 - Expense of unlading and handling.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Molasses § 151.29 Expense of unlading and handling. No expense incidental to the unlading, transporting, or handling of sugar, sirup, or molasses for convenient weighing, gaging, measuring, sampling, or marking...

  1. 49 CFR 172.317 - KEEP AWAY FROM HEAT handling mark.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 49 Transportation 2 2011-10-01 2011-10-01 false KEEP AWAY FROM HEAT handling mark. 172.317 Section... REQUIREMENTS, AND SECURITY PLANS Marking § 172.317 KEEP AWAY FROM HEAT handling mark. (a) General. For... of Division 5.2 must be marked with the KEEP AWAY FROM HEAT handling mark specified in this section...

  2. 49 CFR 172.317 - KEEP AWAY FROM HEAT handling mark.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false KEEP AWAY FROM HEAT handling mark. 172.317 Section... REQUIREMENTS, AND SECURITY PLANS Marking § 172.317 KEEP AWAY FROM HEAT handling mark. (a) General. For... of Division 5.2 must be marked with the KEEP AWAY FROM HEAT handling mark specified in this section...

  3. Status and path to a final EUVL reticle-handling solution

    NASA Astrophysics Data System (ADS)

    He, Long; Orvek, Kevin; Seidel, Phil; Wurm, Stefan; Underwood, Jon; Betancourt, Ernie

    2007-03-01

    In extreme ultraviolet lithography (EUVL), the lack of a suitable material to build conventional pellicles calls for industry standardization of new techniques for protection and handling throughout the reticle's lifetime. This includes reticle shipping, robotic handling, in-fab transport, storage, and uses in atmospheric environments for metrology and vacuum environments for EUV exposure. In this paper, we review the status of the industry-wide progress in developing EUVL reticle-handling solutions. We show the industry's leading reticle carrier approaches for particle-free protection, such as improvements in conventional single carrier designs and new EUVL-specific carrier concepts, including variations on a removable pellicle. Our test indicates dual pod approach of the removable pellicle led to nearly particle-free use during a simulated life cycle, at ~50nm inspection sensitivity. We will provide an assessment of the remaining technical challenges facing EUVL reticle-handling technology. Finally, we will review the progress of the SEMI EUVL Reticle-handling Task Force in its efforts to standardize a final EUV reticle protection and handling solution.

  4. Serotype-Specific Neutralizing Antibody Epitopes of Human Adenovirus Type 3 (HAdV-3) and HAdV-7 Reside in Multiple Hexon Hypervariable Regions

    PubMed Central

    Qiu, Hongling; Li, Xiao; Tian, Xingui; Zhou, Zhichao; Xing, Ke; Li, Haitao; Tang, Ni; Liu, Wenkuan; Bai, Peisheng

    2012-01-01

    Human adenovirus types 3 and 7 (HAdV-3 and HAdV-7) occur epidemically and contribute greatly to respiratory diseases, but there is no currently available licensed recombinant HAdV-3/HAdV-7 bivalent vaccine. Identification of serotype-specific neutralizing antibody (NAb) epitopes for HAdV-3 and HAdV-7 will be beneficial for development of recombinant HAdV-3/HAdV-7 bivalent vaccines. In this study, four NAb epitopes within hexon hypervariable regions (HVRs) were predicted for HAdV-3 and HAdV-7, respectively, by using bioinformatics. Eight hexon chimeric adenovirus vectors with the alternation of only one predicted neutralizing epitope were constructed. Further in vitro and in vivo neutralization assays indicated that E2 (residing in HVR2) and E3 (residing in HVR5) are NAb epitopes for HAdV-7, and E3 plays a more important role in generating NAb responses. Cross-neutralization assays indicated that all four predicted epitopes, R1 to R4, are NAb epitopes for HAdV-3, and R1 (residing in HVR1) plays the most important role in generating NAb responses. Humoral immune responses elicited by the recombinant rAdH7R1 (containing the R1 epitope) were significantly and durably suppressed by HAdV-3-specific NAbs. Surprisingly, the rAdΔE3GFP-specific neutralizing epitope responses induced by rAdMHE3 (R3 replaced by E3) and rAdMHE4 (R4 replaced by E4) were weaker than those of rAdMHE1 (R1 replaced by E1) or rAdMHE2 (R2 relaced by E2) in vitro and in vivo. Furthermore, rAdMHE4 replicated more slowly in HEp-2 cells, and the final yield was about 10-fold lower than that of rAdΔE3GFP. The current findings contribute not only to the development of new adenovirus vaccine candidates, but also to the construction of new gene delivery vectors. PMID:22623776

  5. Modulation of the Metabiome by Rifaximin in Patients with Cirrhosis and Minimal Hepatic Encephalopathy

    PubMed Central

    Bajaj, Jasmohan S.; Heuman, Douglas M.; Sanyal, Arun J.; Hylemon, Phillip B.; Sterling, Richard K.; Stravitz, R. Todd; Fuchs, Michael; Ridlon, Jason M.; Daita, Kalyani; Monteith, Pamela; Noble, Nicole A.; White, Melanie B.; Fisher, Andmorgan; Sikaroodi, Masoumeh; Rangwala, Huzefa; Gillevet, Patrick M.

    2013-01-01

    Hepatic encephalopathy (HE) represents a dysfunctional gut-liver-brain axis in cirrhosis which can negatively impact outcomes. This altered gut-brain relationship has been treated using gut-selective antibiotics such as rifaximin, that improve cognitive function in HE, especially its subclinical form, minimal HE (MHE). However, the precise mechanism of the action of rifaximin in MHE is unclear. We hypothesized that modulation of gut microbiota and their end-products by rifaximin would affect the gut-brain axis and improve cognitive performance in cirrhosis. Aim To perform a systems biology analysis of the microbiome, metabolome and cognitive change after rifaximin in MHE. Methods Twenty cirrhotics with MHE underwent cognitive testing, endotoxin analysis, urine/serum metabolomics (GC and LC-MS) and fecal microbiome assessment (multi-tagged pyrosequencing) at baseline and 8 weeks post-rifaximin 550 mg BID. Changes in cognition, endotoxin, serum/urine metabolites (and microbiome were analyzed using recommended systems biology techniques. Specifically, correlation networks between microbiota and metabolome were analyzed before and after rifaximin. Results There was a significant improvement in cognition(six of seven tests improved,p<0.01) and endotoxemia (0.55 to 0.48 Eu/ml, p = 0.02) after rifaximin. There was a significant increase in serum saturated (myristic, caprylic, palmitic, palmitoleic, oleic and eicosanoic) and unsaturated (linoleic, linolenic, gamma-linolenic and arachnidonic) fatty acids post-rifaximin. No significant microbial change apart from a modest decrease in Veillonellaceae and increase in Eubacteriaceae was observed. Rifaximin resulted in a significant reduction in network connectivity and clustering on the correlation networks. The networks centered on Enterobacteriaceae, Porphyromonadaceae and Bacteroidaceae indicated a shift from pathogenic to beneficial metabolite linkages and better cognition while those centered on autochthonous taxa

  6. Prospective evaluation of the impact of covert hepatic encephalopathy on quality of life and sleep in cirrhotic patients.

    PubMed

    Labenz, C; Baron, J S; Toenges, G; Schattenberg, J M; Nagel, M; Sprinzl, M F; Nguyen-Tat, M; Zimmermann, T; Huber, Y; Marquardt, J U; Galle, P R; Wörns, M-A

    2018-06-04

    Minimal hepatic encephalopathy (HE) and HE grade 1 (HE1) according to the West Haven criteria have recently been grouped as one entity named-covert HE- (CHE). Data regarding the impact of CHE on health-related quality of life (HRQoL) and sleep quality are controversial. First, to determine whether CHE affects HRQoL and sleep quality of cirrhotic patients and second, whether minimal HE (MHE) and HE1 affect HRQoL and sleep quality to a comparable extent. A total of 145 consecutive cirrhotic patients were enrolled. HE1 was diagnosed clinically according to the West Haven criteria. Critical flicker frequency and the Psychometric Hepatic Encephalopathy Score were used to detect MHE. Chronic Liver Disease Questionnaire (CLDQ) was used to assess HRQoL and Pittsburgh Sleep Quality Index (PSQI) was applied to assess sleep quality. Covert HE was detected in 59 (40.7%) patients (MHE: n = 40; HE1: n = 19). Multivariate analysis identified CHE (P < 0.001) and female gender (P = 0.006) as independent predictors of reduced HRQoL (CLDQ total score). CHE (P = 0.021), low haemoglobin (P = 0.024) and female gender (P = 0.003) were identified as independent predictors of poor sleep quality (PSQI total score). Results of CLDQ and PSQI were comparable in patients with HE1 and MHE (CLDQ: 4.6 ± 0.9 vs 4.5 ± 1.2, P = 0.907; PSQI: 11.3 ± 3.8 vs 9.9 ± 5.0, P = 0.3). Covert HE was associated with impaired HRQoL and sleep quality. MHE and HE1 affected both outcomes to a comparable extent supporting the use of CHE as a clinically useful term for patients with both entities of HE in clinical practice. © 2018 John Wiley & Sons Ltd.

  7. Aircraft Handling Qualities Data

    DTIC Science & Technology

    1972-12-01

    WITH YOUR INQUIRY 02672-931227121247 DEPT OF DEFENSE DEFENSE TECHNICAL INFORMATION CENTER ATTN: DTIC-OCP/JOYCE CHIRAS CAMERON STATION BLDG 9...Handling Qualities, F-IO4A, Lockheed Rept. t No. LR 10794, 12 Dec. 19ř Andrews, William H., and Herman A. Rediess, Flight-Determined Eta- bility and

  8. 46 CFR 30.10-6 - Cargo handling room-TB/ALL.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 1 2013-10-01 2013-10-01 false Cargo handling room-TB/ALL. 30.10-6 Section 30.10-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-6 Cargo handling room—TB/ALL. The term cargo handling room means any enclosed space where cargo is pumped...

  9. 46 CFR 30.10-6 - Cargo handling room-TB/ALL.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Cargo handling room-TB/ALL. 30.10-6 Section 30.10-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-6 Cargo handling room—TB/ALL. The term cargo handling room means any enclosed space where cargo is pumped...

  10. 46 CFR 30.10-6 - Cargo handling room-TB/ALL.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 1 2011-10-01 2011-10-01 false Cargo handling room-TB/ALL. 30.10-6 Section 30.10-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-6 Cargo handling room—TB/ALL. The term cargo handling room means any enclosed space where cargo is pumped...

  11. 46 CFR 30.10-6 - Cargo handling room-TB/ALL.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 1 2014-10-01 2014-10-01 false Cargo handling room-TB/ALL. 30.10-6 Section 30.10-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-6 Cargo handling room—TB/ALL. The term cargo handling room means any enclosed space where cargo is pumped...

  12. 46 CFR 30.10-6 - Cargo handling room-TB/ALL.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 1 2012-10-01 2012-10-01 false Cargo handling room-TB/ALL. 30.10-6 Section 30.10-6 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY TANK VESSELS GENERAL PROVISIONS Definitions § 30.10-6 Cargo handling room—TB/ALL. The term cargo handling room means any enclosed space where cargo is pumped...

  13. Listing of Food Service Equipment.

    ERIC Educational Resources Information Center

    National Sanitation Foundation, Ann Arbor, MI. Testing Lab.

    A comprehensive listing of food service equipment including--(1) companies authorized to use the National Sanitation Foundation seal of approval, and (2) equipment listed as meeting NSF standards including soda fountains, spray-type dishwashers, dishwashing equipment, cooking equipment, commerical cooking and warming equipment, freezers,…

  14. Use of the DPP4BIT System for the Management of Hospital Medical Equipment.

    PubMed

    Tsoromokos, Dimitrios; Tsaloukidis, Nikolaos; Zarakovitis, Dimitrios; Lazakidou, Athina

    2017-01-01

    The Information and Communication Technologies (ICT) combined with the development of innovative skills within the broader health sector, can significantly improve and upgrade health care quality services. The proposed DDP4BIT system supports an alternative channel for digital information recording and equipment handling of Biomedical Technology Departments (BITs) of Health Care Units. This technology is ideal for all types of procedures based on handwritten forms that are commonly used in Health Care Units. The collection of useful statistics for analyzing and exporting data indicators is used in order to reduce ratios, such as operating time ratio, ideal operating time indicator, number of repetitive quality failures, total maintenance cost, etc. and supports decision-making.

  15. Use of the Kelly Decontamination System for the cleanup of the auxiliary and fuel-handling buildings at TMI-2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hoyt, K.R.; Pavelek, M.D. II

    1987-01-01

    Following the accident at Three Mile Island Unit 2 (TMI-2) substantial areas in the auxiliary and fuel-handling buildings were contaminated. Overflowing sumps backed up floor drains and contaminated a substantial portion of the 282-ft elevation floor. In addition, contamination was spread into the overheads when the nitrogen purge system, which had become internally contaminated, was relieved of overpressure. Operating experience with the Kelly Decontamination System has been exceptional. The system has been defined as a tool of the trade for labor personnel to operate as part of their duties. A detailed training program was provided by the Kelly Division ofmore » Container Products Corporation for the engineers who then trained labor personnel in the operation of the equipment. There were very few problems with personnel on the equipment for routine decontamination operations. The Kelly Decontamination System has proven to be a dose and cost-effective alternative to hands-on decontamination techniques at TMI-2 and should have wide application for large-scale decontamination operations.« less

  16. Complying with US and European complaint handling requirements.

    PubMed

    Donawa, M E

    1997-09-01

    The importance of customer complaints for providing valuable information on the use of medical devices is clearly reflected in United States (US) and European quality system requirements for handling complaints. However, there are significant differences in US and European complaint handling requirements. This article will discuss those differences and methods for ensuring compliance.

  17. 46 CFR 154.1850 - Entering cargo handling spaces.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Entering cargo handling spaces. 154.1850 Section 154... cargo handling spaces. (a) The master shall ensure that the ventilation system under § 154.1200 is in operation for 30 minutes before a person enters one of the following: (1) Spaces containing cargo pumps...

  18. 46 CFR 154.1850 - Entering cargo handling spaces.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Entering cargo handling spaces. 154.1850 Section 154... cargo handling spaces. (a) The master shall ensure that the ventilation system under § 154.1200 is in operation for 30 minutes before a person enters one of the following: (1) Spaces containing cargo pumps...

  19. 46 CFR 154.1850 - Entering cargo handling spaces.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Entering cargo handling spaces. 154.1850 Section 154... cargo handling spaces. (a) The master shall ensure that the ventilation system under § 154.1200 is in operation for 30 minutes before a person enters one of the following: (1) Spaces containing cargo pumps...

  20. 46 CFR 154.1850 - Entering cargo handling spaces.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 5 2011-10-01 2011-10-01 false Entering cargo handling spaces. 154.1850 Section 154... cargo handling spaces. (a) The master shall ensure that the ventilation system under § 154.1200 is in operation for 30 minutes before a person enters one of the following: (1) Spaces containing cargo pumps...

  1. 46 CFR 154.1850 - Entering cargo handling spaces.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 5 2014-10-01 2014-10-01 false Entering cargo handling spaces. 154.1850 Section 154... cargo handling spaces. (a) The master shall ensure that the ventilation system under § 154.1200 is in operation for 30 minutes before a person enters one of the following: (1) Spaces containing cargo pumps...

  2. 9 CFR 442.5 - Handling of failed product.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 9 Animals and Animal Products 2 2011-01-01 2011-01-01 false Handling of failed product. 442.5 Section 442.5 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... upon testing in accordance with the methods prescribed in § 442.2 of this subchapter shall be handled...

  3. 9 CFR 442.5 - Handling of failed product.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Handling of failed product. 442.5 Section 442.5 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... upon testing in accordance with the methods prescribed in § 442.2 of this subchapter shall be handled...

  4. 9 CFR 442.5 - Handling of failed product.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 9 Animals and Animal Products 2 2012-01-01 2012-01-01 false Handling of failed product. 442.5 Section 442.5 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... upon testing in accordance with the methods prescribed in § 442.2 of this subchapter shall be handled...

  5. 9 CFR 442.5 - Handling of failed product.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 9 Animals and Animal Products 2 2014-01-01 2014-01-01 false Handling of failed product. 442.5 Section 442.5 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... upon testing in accordance with the methods prescribed in § 442.2 of this subchapter shall be handled...

  6. 9 CFR 442.5 - Handling of failed product.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 9 Animals and Animal Products 2 2013-01-01 2013-01-01 false Handling of failed product. 442.5 Section 442.5 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE... upon testing in accordance with the methods prescribed in § 442.2 of this subchapter shall be handled...

  7. Hyperbaric Chamber Equipment: A Consolidated Equipment List from Selected Multiplace Hyperbaric Facilities.

    DTIC Science & Technology

    1983-12-01

    carbon dioxide scrubbers , air conditioning, communications, lighting, and fire detecting and fire extinguishing systems. Medical support equipment was...10 14 Humidity...............................11 5. Hydrocarb on...........................11 B. Carbon Dioxide Scrubbers .....................11 C...and ancillary equipment included gas/vapor monitoring equipment, carbon dioxide scrubbers , air conditioning, communications, lighting, and fire

  8. EPA’s Response Equipment

    EPA Pesticide Factsheets

    EPA maintains a variety of equipment to respond to hazardous substance emergencies such as releases or oil spills regardless of their nature, size, or location. This include ASPECT, PHILIS, Equipment Module (EM), and personal protective equipment.

  9. Project Execution Plan for the Remote Handled Low-Level Waste Disposal Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Danny Anderson

    2014-07-01

    As part of ongoing cleanup activities at the Idaho National Laboratory (INL), closure of the Radioactive Waste Management Complex (RWMC) is proceeding under the Comprehensive Environmental Response, Compensation, and Liability Act (42 USC 9601 et seq. 1980). INL-generated radioactive waste has been disposed of at RWMC since 1952. The Subsurface Disposal Area (SDA) at RWMC accepted the bulk of INL’s contact and remote-handled low-level waste (LLW) for disposal. Disposal of contact-handled LLW and remote-handled LLW ion-exchange resins from the Advanced Test Reactor in the open pit of the SDA ceased September 30, 2008. Disposal of remote-handled LLW in concrete disposalmore » vaults at RWMC will continue until the facility is full or until it must be closed in preparation for final remediation of the SDA (approximately at the end of fiscal year FY 2017). The continuing nuclear mission of INL, associated ongoing and planned operations, and Naval spent fuel activities at the Naval Reactors Facility (NRF) require continued capability to appropriately dispose of contact and remote handled LLW. A programmatic analysis of disposal alternatives for contact and remote-handled LLW generated at INL was conducted by the INL contractor in Fiscal Year 2006; subsequent evaluations were completed in Fiscal Year 2007. The result of these analyses was a recommendation to the Department of Energy (DOE) that all contact-handled LLW generated after September 30, 2008, be disposed offsite, and that DOE proceed with a capital project to establish replacement remote-handled LLW disposal capability. An analysis of the alternatives for providing replacement remote-handled LLW disposal capability has been performed to support Critical Decision-1. The highest ranked alternative to provide this required capability has been determined to be the development of a new onsite remote-handled LLW disposal facility to replace the existing remote-handled LLW disposal vaults at the SDA. Several

  10. Staphylococcus xylosus PCR-validated Decontamination of Murine Individually Ventilated Cage Racks and Air Handling Units by Using 'Active-Closed' Exposure to Vaporized Hydrogen Peroxide.

    PubMed

    Ragland, Natalie H; Miedel, Emily L; Gomez, Jose M; Engelman, Robert W

    2017-11-01

    Vaporized hydrogen peroxide (VHP) is used to decontaminate clinical, biocontainment, and research animal rooms and equipment. To assist with its implementation in a murine facility, we developed a safe and effective method of VHP sterilization of IVC racks and air handling units (AHU). Safety of VHP decontamination was assessed by ensuring VHP levels dissipated to less than 1 ppm in the room prior to personnel reentry and inside the primary enclosure prior to the return of mice; this condition occurred at least 18 h after the VHP cycle. Efficacy of VHP sterilization was assessed by using chemical indicators, biologic indicators, and PCR testing for Staphylococcus xylosus, a commensal organism of murine skin and an opportunistic pathogen, which was present in 160 of 172 (93%) of specimens from occupied IVC racks and the interior surfaces of in-use AHU. Neither mechanized washing nor hand-sanitizing eradicated S. xylosus from equipment airway interiors, with 17% to 24% of specimens remaining PCR-positive for S. xylosus. 'Static-open' VHP exposure of sanitized equipment did not ensure its sterilization. In contrast, 'active-closed' VHP exposure, in which IVC racks were assembled, sealed, and connected to AHU set to the VHP cycle, increased the proportion of chemical indicators that detected sterilizing levels of VHP inside the assembled equipment, and significantly decreased PCR-detectable S. xylosus inside the equipment. Supplementing bulk steam sterilization of the primary enclosure with VHP sterilization of the secondary housing equipment during room change-outs may help to mitigate opportunistic agents that jeopardize studies involving immunodeficient strains.

  11. Manual handling risks associated with the care, treatment and transportation of bariatric (severely obese) clients in Australia.

    PubMed

    Cowley, Stephen P; Leggett, Susan

    2011-01-01

    Carers of bariatric (morbidly obese) clients are exposed to manual handling injury risk throughout the journey that such clients take within the healthcare system. To identify the factors that affect risks associated with bariatric clients and the subsequent adoption of risk control measures focus groups were conducted in two Australian state capitals: a suburban region of Melbourne and a large regional Victorian town. Participants, were recruited from within the primary health care sector, ambulance services, fire services and funeral businesses. It was found that the risks to which nurses, ambulance officers, fire fighters, and funeral industry employees are exposed are significant. The injury risk is influenced by the nature and design of the range of environments within which client movement is undertaken; the limited range of handling equipment available for use with bariatric clients; and the efficacy of organisational procedures and training. Adoption of risk controls is hampered by the absence of a standard definition of the term ``bariatric'' and the gaps in information flow during the bariatric client journey through the health care system. Various definitions of bariatric are applied in different sectors and there are limitations to the use of both weight and body mass index in those definitions.

  12. Is the current level of training in the use of equipment for prehospital radio communication sufficient? A cross-sectional study among prehospital physicians in Denmark

    PubMed Central

    2017-01-01

    Background Physicians working in prehospital care are expected to handle radio communication both within their own sector as well as with other divisions of the National Emergency Services. To date, no study has been conducted on the level of training received by physicians in the use of the equipment provided or on the level of competency acquired by physicians. Methods In order to investigate the self-assessed skill level acquired in the use of the TETRA (TErrestrial Trunked RAdio) authority radio for communication in a prehospital setting, a cross-sectional study was conducted by questionnaire circulated to all 454 physicians working in the Danish Emergency Medical Services. Results A lack of training was found among physicians working in prehospital care in Denmark in relation to the proper use of essential communication equipment. Prior to starting their first shift in a prehospital setting 38% of physicians reported having received no training in the use of the equipment, while 80% of physicians reported having received one1 hour of training or less. Among the majority of physicians their current level of training was sufficient for their everyday needs for prehospital communication but for 28% of physicians their current level of training was insufficient as they were unable to handle communication at this level. Conclusion As the first study in its field, this study investigated the training received in the use of essential communication equipment among physicians working in prehospital care in Denmark. The study found that competency does not appear to have been prioritised as highly as other technical skills needed to function in these settings. For the majority of physicians their current level of training was sufficient for everyday use but for a substantial minority further training is required, especially if the redundancy of the prehospital system is to be preserved. PMID:28667210

  13. NASA Space Program experience in hydrogen transportation and handling

    NASA Technical Reports Server (NTRS)

    Bain, A. L.

    1976-01-01

    This paper portrays the experience gained in the transportation and handling of hydrogen in support of the Apollo launch site at Kennedy Space Center (KSC), Fla., one of NASA's prime hydrogen users in the Space Program. The objective of the paper is basically to reveal the types of systems involved in handling hydrogen, safety practices, operational techniques, other general experience information, and primarily to convey the routinism by which this potential fuel of the future has already been handled in significant quantities for a number of years.

  14. Ground data handling for Landsat-D. [for thematic mapper

    NASA Technical Reports Server (NTRS)

    Lynch, T. J.

    1977-01-01

    The present plans for the Landsat-D ground data handling are described in relationship to the mission objectives and the planned spacecraft system. The end-to-end data system is presented with particular emphasis on the data handling plans for the new instrument, the Thematic Mapper. This instrument generates ten times the amount of data per scene as the present Multispectral Scanner and this resulting data rate and volume are discussed as well as possible new data techniques to handle them - such as image compression.

  15. Particle release and control of worker exposure during laboratory-scale synthesis, handling and simulated spills of manufactured nanomaterials in fume hoods

    NASA Astrophysics Data System (ADS)

    Fonseca, Ana S.; Kuijpers, Eelco; Kling, Kirsten I.; Levin, Marcus; Koivisto, Antti J.; Nielsen, Signe H.; Fransman, W.; Fedutik, Yijri; Jensen, Keld A.; Koponen, Ismo K.

    2018-02-01

    Fume hoods are one of the most common types of equipment applied to reduce the potential of particle exposure in laboratory environments. A number of previous studies have shown particle release during work with nanomaterials under fume hoods. Here, we assessed laboratory workers' inhalation exposure during synthesis and handling of CuO, TiO2 and ZnO in a fume hood. In addition, we tested the capacity of a fume hood to prevent particle release to laboratory air during simulated spillage of different powders (silica fume, zirconia TZ-3Y and TiO2). Airborne particle concentrations were measured in near field, far field, and in the breathing zone of the worker. Handling CuO nanoparticles increased the concentration of small particles (< 58 nm) inside the fume hood (up to 1 × 105 cm-3). Synthesis, handling and packaging of ZnO and TiO2 nanoparticles did not result in detectable particle release to the laboratory air. Simulated powder spills showed a systematic increase in the particle concentrations inside the fume hood with increasing amount of material and drop height. Despite powder spills were sometimes observed to eject into the laboratory room, the spill events were rarely associated with notable release of particles from the fume hood. Overall, this study shows that a fume hood generally offers sufficient exposure control during synthesis and handling of nanomaterials. An appropriate fume hood with adequate sash height and face velocity prevents 98.3% of particles release into the surrounding environment. Care should still be made to consider spills and high cleanliness to prevent exposure via resuspension and inadvertent exposure by secondary routes.

  16. Grain Grading and Handling.

    ERIC Educational Resources Information Center

    Rendleman, Matt; Legacy, James

    This publication provides an introduction to grain grading and handling for adult students in vocational and technical education programs. Organized in five chapters, the booklet provides a brief overview of the jobs performed at a grain elevator and of the techniques used to grade grain. The first chapter introduces the grain industry and…

  17. New weight-handling device for commercial oil pressure balances

    NASA Astrophysics Data System (ADS)

    Woo, S. Y.; Choi, I. M.; Kim, B. S.

    2005-12-01

    This paper presents a new device to automatically handle a large number of weights for the calibration of a pressure gauge. This newly invented weight-handling device is made for use in conjunction with a commercial oil pressure balance. Although the pressure balance is essential as a calibration tool, its use has been generally tedious and labour intensive for a long time. In particular, the process of loading a different combination of weights on the top of a piston requires repetitious manual handling for every new measurement. This inevitably leaves the operator fatigued, and sometimes causes damage to the weights due to careless handling. The newly invented automatic weight-handling device can eliminate such tedious, error-prone and wear-inducing manual weight manipulation. The device consists of a stepping motor, a drive belt, a solenoid valve, three weight-lifting assemblies and three linear-motion guide assemblies. The weight-lifting assembly is composed of a pneumatic actuator, a solid-state switch and a metal finger. It has many advantages compared with the commercial automatic weight-handling device. Firstly, it is not necessary to lift all the weights off the piston in the weight selection process, as it is in the case of the commercial device. Thus it can prevent a permanent deformation of the weight carrier. Secondly, this new device can handle a larger number of weights than the commercial one. This is because the new device adopts a different method in retaining the remaining weights in place. Another advantage of this new device is that there is no possibility of the fingers touching the surface of the weights due to the oscillation of weights. Moreover it uses the general technology of a stepping motor, and is also made up of components that are easily obtainable in the market, thereby being very economical.

  18. Flexible Electrostatic Technologies for Capture and Handling, Phase 1

    NASA Technical Reports Server (NTRS)

    Bryan, Thomas

    2015-01-01

    Fundamental to many of NASA's in-space transportation missions is the capture and handling of various objects and vehicles in various orbits for servicing, debris disposal, sample retrieval, and assembly without the benefit of sufficient grapple fixtures and docking ports. To perform similar material handling tasks on Earth, pincher grippers, suction grippers, or magnetic chucks are used, but are unable to reliably grip aluminum and composite spacecraft, insulation, radiators, solar arrays, or extra-terrestrial objects in the vacuum of outer space without dedicated handles in the right places. The electronic Flexible Electrostatic Technologies for space Capture and Handling (FETCH) will enable reliable and compliant gripping (soft dock) of practically any object in various orbits or surfaces without dedicated mechanical features, very low impact capture, and built-in proximity sensing without any conventional actuators. Originally developed to handle semiconductor and glass wafers during vacuum chamber processing without contamination, the normal rigid wafer handling chucks are replaced with thin metal foil segments laminated in flexible insulation driven by commercial off-the-shelf solid state, high-voltage power supplies. Preliminary testing in NASA Marshall Space Flight Center's (MSFC's) Flat Floor Robotics Lab demonstrated compliant alignment and gripping with a full-sized, 150-lb microsat mockup and translation before a clean release with a flip of a switch. The flexible electrostatic gripper pads can be adapted to various space applications with different sizes, shapes, and foil electrode layouts even with openings through the gripper pads for addition of guidance sensors or injection of permanent adhesives. With gripping forces estimated between 0.5 and 2.5 lb/in2 or 70-300 lb/ft2 of surface contact, the FETCH can turn on and off rapidly and repeatedly to enable sample handling, soft docking, in-space assembly, precision relocation, and surface translation

  19. AAFP and ISFM feline-friendly handling guidelines.

    PubMed

    Rodan, Ilona; Sundahl, Eliza; Carney, Hazel; Gagnon, Anne-Claire; Heath, Sarah; Landsberg, Gary; Seksel, Kersti; Yin, Sophia

    2011-05-01

    The number of pet cats is increasing in most countries, often outnumbering pet dogs, yet cats receive less veterinary care than their canine counterparts.(1) Clients state the difficulty of getting the cat into a carrier at home, driving to the clinic, and dealing with the fearful cat at the veterinary clinic as reasons for fewer visits.(2) Educating and preparing the client and the veterinary team with regard to respectful feline handling is necessary in order to avoid stress and accomplish the goal of good health care. Without such preparation, feline stress may escalate into fear or fear-associated aggression. The resulting stress may alter results of the physical examination and laboratory tests, leading to incorrect diagnoses (eg, diabetes mellitus) and unnecessary treatments.(3-5) Without compassionate and respectful handling by the veterinary team, clients may feel the team lacks skills and compassion, or does not understand cats. Injury may occur to the cat, client and/or veterinary team.(6) Clients who want to avoid stress for their cat may avoid veterinary visits or choose another practice instead. The use of feline-friendly handling techniques should reduce these problems. Handling is most successful when the veterinary team adapts the approach to each individual cat and situation. The goal of these guidelines is to provide useful information for handling cats that can lead to: ✜ Reduced fear and pain for the cat. ✜ Reinforced veterinarian-client-cat bond, trust and confidence, and thus better lifelong medical care for the cat. ✜ Improved efficiency, productivity and job satisfaction for the veterinary team. ✜ Increased client compliance. ✜ Timely reporting and early detection of medical and behavioral concerns. ✜ Fewer injuries to clients and the veterinary team. ✜ Reduced anxiety for the client. Copyright © 2011 Elsevier Inc. All rights reserved.

  20. Data handling and representation of freeform surfaces

    NASA Astrophysics Data System (ADS)

    Steinkopf, Ralf; Dick, Lars; Kopf, Tino; Gebhardt, Andreas; Risse, Stefan; Eberhardt, Ramona

    2011-10-01

    Freeform surfaces enable innovative optics. They are not limited by axis symmetry and hence they are almost free in design. They are used to reduce the installation space and enhance the performance of optical elements. State of the art optical design tools are computing with powerful algorithms to simulate freeform surfaces. Even new mathematical approaches are under development /1/. In consequence, new optical designs /2/ are pushing the development of manufacturing processes consequently and novel types of datasets have to proceed through the process chain /3/. The complexity of these data is the huge challenge for the data handling. Because of the asymmetrical and 3-dimensional surfaces of freeforms, large data volumes have to be created, trimmed, extended and fitted. All these processes must be performed without losing the accuracy of the original design data. Additionally, manifold types of geometries results in different kinds of mathematical representations of freeform surfaces and furthermore the used CAD/CAM tools are dealing with a set of spatial transport formats. These are all reasons why manufacture-oriented approaches for the freeform data handling are not yet sufficiently developed. This paper suggests a classification of freeform surfaces based on the manufacturing methods which are offered by diamond machining. The different manufacturing technologies, ranging from servo-turning to shaping, require a differentiated approach for the data handling process. The usage of analytical descriptions in form of splines and polynomials as well as the application of discrete descriptions like point clouds is shown in relation to the previously made classification. Advantages and disadvantages of freeform representations are discussed. Aspects of the data handling in between different process steps are pointed out and suitable exchange formats for freeform data are proposed. The described approach offers the possibility for efficient data handling from optical

  1. Paratransit Vehicle Test and Evaluation : Volume 3. Handling Tests.

    DOT National Transportation Integrated Search

    1978-06-01

    A series of tests and evaluations of two prototype vehicles for paratransit were conducted. This volume (Volume III) presents the test procedures and results of the handling test series. The test determined the steering and handling characteristics o...

  2. Fleet Sizing of Automated Material Handling Using Simulation Approach

    NASA Astrophysics Data System (ADS)

    Wibisono, Radinal; Ai, The Jin; Ratna Yuniartha, Deny

    2018-03-01

    Automated material handling tends to be chosen rather than using human power in material handling activity for production floor in manufacturing company. One critical issue in implementing automated material handling is designing phase to ensure that material handling activity more efficient in term of cost spending. Fleet sizing become one of the topic in designing phase. In this research, simulation approach is being used to solve fleet sizing problem in flow shop production to ensure optimum situation. Optimum situation in this research means minimum flow time and maximum capacity in production floor. Simulation approach is being used because flow shop can be modelled into queuing network and inter-arrival time is not following exponential distribution. Therefore, contribution of this research is solving fleet sizing problem with multi objectives in flow shop production using simulation approach with ARENA Software

  3. Sectional device handling tool

    DOEpatents

    Candee, Clark B.

    1988-07-12

    Apparatus for remotely handling a device in an irradiated underwater environment includes a plurality of tubular sections interconnected end-to-end to form a handling structure, the bottom section being adapted for connection to the device. A support section is connected to the top tubular section and is adapted to be suspended from an overhead crane. Each section is flanged at its opposite ends. Axially retractable bolts in each bottom flange are threadedly engageable with holes in the top flange of an adjacent section, each bolt being biased to its retracted position and retained in place on the bottom flange. Guide pins on each top flange cooperate with mating holes on adjacent bottom flanges to guide movement of the parts to the proper interconnection orientation. Each section carries two hydraulic line segments provided with quick-connect/disconnect fittings at their opposite ends for connection to the segments of adjacent tubular sections upon interconnection thereof to form control lines which are connectable to the device and to an associated control console.

  4. BONUS Gas Handling System

    NASA Astrophysics Data System (ADS)

    Ferrer, James

    2004-10-01

    The BONUS experiment, at the Thomas Jefferson National Accelerator Facility aims to measure structure functions of the neutron via electron scattering. In order to overcome the unavailability of a neutron target, the BONUS collaboration will use a deuterium target. By detecting the recoil (spectator) proton in coincidence with the scattered electron, the kinematics of the electron-neutron interaction will be fully determined, thus overcoming theoretical complications that arise when extracting neutron cross sections. In order to detect low energy recoil protons, in the 70-100 MeV/c range, a (6 cm-radius) radial time projection chamber (RTPC) will be used. The BONUS RTPC is based on the gas electron multiplier (GEM) technology recently developed at CERN. One of the key components of this detector is the gas handling system, designed and built to deliver the correct mixture of gas to the detector safely, accurately, and reliably. The building and testing of this system is the major contribution of James Madison University to the BONUS collaboration. This poster provides a general overview of the BONUS detector, focusing on the gas handling system.

  5. AVIRIS onboard data handling and control

    NASA Technical Reports Server (NTRS)

    Steinkraus, Ronald E.; Hickok, Roger W.

    1987-01-01

    The timing and flow of detector and ancillary data for the Airborne Visible/Infrared imaging spectrometer (AVIRIS) are controlled within the instrument by its digital electronics assembly. In addition to providing detector and signal chain timing, the digital electronics receives, formats, and rate-buffers digitized science data; collects and formats ancillary (calibration and engineering) data; and merges both into a single tape record. Overall AVIRIS data handling is effected by a combination of dedicated digital electronics to control instrument timing, image data flow, and data rate buffering and a microcomputer programmed to handle real-time control of instrument mechanisms and the coordinated preparation of ancillary data.

  6. 7 CFR 915.141 - Handling avocados for commercial processing into products.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Handling avocados for commercial processing into... AGRICULTURE AVOCADOS GROWN IN SOUTH FLORIDA Rules and Regulations § 915.141 Handling avocados for commercial processing into products. (a) No person shall handle any avocados for commercial processing into products...

  7. 7 CFR 915.141 - Handling avocados for commercial processing into products.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Handling avocados for commercial processing into... AGRICULTURE AVOCADOS GROWN IN SOUTH FLORIDA Rules and Regulations § 915.141 Handling avocados for commercial processing into products. (a) No person shall handle any avocados for commercial processing into products...

  8. 7 CFR 915.141 - Handling avocados for commercial processing into products.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Handling avocados for commercial processing into... AGRICULTURE AVOCADOS GROWN IN SOUTH FLORIDA Rules and Regulations § 915.141 Handling avocados for commercial processing into products. (a) No person shall handle any avocados for commercial processing into products...

  9. 7 CFR 915.141 - Handling avocados for commercial processing into products.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Handling avocados for commercial processing into... AGRICULTURE AVOCADOS GROWN IN SOUTH FLORIDA Rules and Regulations § 915.141 Handling avocados for commercial processing into products. (a) No person shall handle any avocados for commercial processing into products...

  10. Effects of handling procedures on pain responses of very low birth weight infants.

    PubMed

    Cameron, Emma Catherine; Raingangar, Veena; Khoori, Nawal

    2007-01-01

    The purpose of this study was to investigate the effects of handling on pain responses of infants with very low birth weight (VLBW) and the frequency, duration, and type of handling procedures used during a 24-hour period for infants with VLBW. Eighteen infants with VLBW were observed for two-hour periods. Infants' pain responses were recorded using the Neonatal Inventory Pain Scale before and after each handling episode. Twelve infants were observed once, six were observed twice. Variables relating to each handling episode observed were documented. Pain scores were significantly greater after handling. During a 24-hour period, infants were handled an average of 53 times for an average of 2.7 hours. Ten handling episodes included social touch. Handling infants with VLBW significantly alters their pain responses. In some infants with VLBW are handled frequently in the neonatal intensive care unit. The results have implications for the training of neonatal caregivers.

  11. [The Necessity and the Current Status of Safe Handling of Anticancer Drugs].

    PubMed

    Kanda, Kiyoko

    2017-07-01

    Number of people who handle anticancer drugs in their profession is increasing. Anticancer drugs, which are hazardous drugs(HD), exert cytocidal effects on cancer cells, but many have also been shown to have mutagenicity, teratogenicity and carcinogenicity; therefore, safe handling of anticancer drugs is necessary. In July 2015, the first Japanese guidelines for exposure control measures, namely, the "Joint Guidelines for Safe Handling of Cancer Chemotherapy Drugs", were published jointly by 3 societies. Our guideline is the creation of the Japanese Society of Cancer Nursing(JSCN), Japanese Society of Medical Oncology(JSMO)and Japanese Society of Pharmaceutical Oncology(JASPO)and has a historical significance. This paper states the necessity of safe handling of anticancer drugs, Japan's recent movement of safe handling, the introduction of joint guidelines of safe handling of anticancer drugs, and new movement of safe handling of USP chapter 800 in the United States.

  12. AdaFF: Adaptive Failure-Handling Framework for Composite Web Services

    NASA Astrophysics Data System (ADS)

    Kim, Yuna; Lee, Wan Yeon; Kim, Kyong Hoon; Kim, Jong

    In this paper, we propose a novel Web service composition framework which dynamically accommodates various failure recovery requirements. In the proposed framework called Adaptive Failure-handling Framework (AdaFF), failure-handling submodules are prepared during the design of a composite service, and some of them are systematically selected and automatically combined with the composite Web service at service instantiation in accordance with the requirement of individual users. In contrast, existing frameworks cannot adapt the failure-handling behaviors to user's requirements. AdaFF rapidly delivers a composite service supporting the requirement-matched failure handling without manual development, and contributes to a flexible composite Web service design in that service architects never care about failure handling or variable requirements of users. For proof of concept, we implement a prototype system of the AdaFF, which automatically generates a composite service instance with Web Services Business Process Execution Language (WS-BPEL) according to the users' requirement specified in XML format and executes the generated instance on the ActiveBPEL engine.

  13. Rifaximin Improves Driving Simulator Performance in a Randomized Trial of Patients with Minimal Hepatic Encephalopathy

    PubMed Central

    Bajaj, Jasmohan S; Heuman, Douglas M; Wade, James B; Gibson, Douglas P; Saeian, Kia; Wegelin, Jacob A; Hafeezullah, Muhammad; Bell, Debulon E; Sterling, Richard K; Stravitz, R. Todd; Fuchs, Michael; Luketic, Velimir; Sanyal, Arun J

    2010-01-01

    Background & Aims Patients with cirrhosis and minimal hepatic encephalopathy (MHE) have driving difficulties but the effects of therapy on driving performance have not been assessed. We evaluated whether performance on a driving simulator improves in patients with MHE following treatment with rifaximin. Methods Patients with MHE who were current drivers were randomly assigned to placebo or rifaximin groups and followed for 8 weeks (n=42). Patients underwent driving simulation (driving and navigation tasks) at the start (baseline) and end of the study. We evaluated patients’ cognitive abilities, quality-of-life (using the Sickness Impact Profile [SIP]), serum levels of ammonia, levels of inflammatory cytokines, and MELD scores. The primary outcome was percent who improved in driving performance, calculated by: total driving errors=speeding + illegal turns + collisions. Results Over the 8-week study period, patients given rifaximin made significantly greater improvements than those given placebo in avoiding total driving errors (76% vs. 31%, P=0.013), speeding (81% vs. 33%, P=0.005), and illegal turns (62% vs. 19%, P=0.01). Of patients given rifaximin, 91% improved their cognitive performance, compared with 61% of patients given placebo (P=0.01); they also made improvements in the psycho-social dimension of the SIP, compared with the placebo group (P=0.04). Adherence to the assigned drug averaged 92%. Neither group had changes in ammonia levels or MELD scores, but patients in the rifaximin group had increased levels of the anti-inflammatory cytokine interleukin-10. Conclusions Patients with MHE significantly improve driving simulator performance following treatment with rifaximin, compared with placebo. PMID:20849805

  14. Exercise Equipment: Neutral Buoyancy

    NASA Technical Reports Server (NTRS)

    Shackelford, Linda; Valle, Paul

    2016-01-01

    Load Bearing Equipment for Neutral Buoyancy (LBE-NB) is an exercise frame that holds two exercising subjects in position as they apply counter forces to each other for lower extremity and spine loading resistance exercises. Resistance exercise prevents bone loss on ISS, but the ISS equipment is too massive for use in exploration craft. Integrating the human into the load directing, load generating, and motion control functions of the exercise equipment generates safe exercise loads with less equipment mass and volume.

  15. Achieving 'excellent' indoor air quality in commercial offices equipped with air-handling unit--respirable suspended particulate.

    PubMed

    Lam, K S; Chan, F S; Fung, W Y; Lui, B S S; Lau, L W L

    2006-04-01

    A study was carried out to investigate the feasibility of achieving ultra low respirable suspended particulates (RSP) in commercial offices without major modification of existing ventilation systems by enhancing the particulates removal efficiency of existing central ventilation systems. Four types of filters which include pre-filters, cartridge filters, bag filters and high efficiency particulates air (HEPA) filters were tested in a commercial building in Causeway Bay. The results show that an RSP objective of <20 microg/m3 could be met by removing RSP from both the return air and outdoor air supply simultaneously. This level of performance is classed as 'excellent' by the Hong Kong Government, Environmental Protection Department. Filters with efficiency that exceed 80% placed both in the return air and outdoor air were sufficient to meet the objective. It is not necessary to install HEPA filters to achieve the 'excellent' class. The outdoor air filter has great influence on the steady state indoor RSP concentration while the effective cleaning rate is governed by the return air filter. Higher efficiency filters increased the static drop but the volume flow of the air fan was not affected significantly. The additional cost incurred was <5% of the existing operation cost. This paper reports a field study of RSP control for an indoor office environment. The results are directly applicable to building service engineering in the design of ventilation systems using air-handling units. Field observations indicated that indoor RSP in an office environment could be suppressed below 20 microg/m3 within 1 h by the simultaneous filtration of outdoor air and return air. Outdoor air filtration has a great influence on the steady state indoor concentration and return air filtration governs the cleaning rate. It is believed that the results of this study could be extended to the cleaning of other indoor pollutants such as volatile organic compounds.

  16. Brief early handling increases morphine dependence in adult rats.

    PubMed

    Vazquez, Vincent; Penit-Soria, Jacqueline; Durand, Claudette; Besson, Marie-Jo; Giros, Bruno; Daugé, Valérie

    2006-06-30

    Short early manipulations of rodent postnatal environment may trigger long-term effects on neurobiological and behavioural phenotypes in adulthood. However, little is known about such effects of handling on the vulnerability to develop drug dependence. The present study aimed to analyze the long-term effects of a brief handling (1 min) on morphine and ethanol dependence and on the preproenkephalin (PPE) mRNA and mu opioid receptor levels. Handled rats showed a significant increase in morphine (25mg/l) but not ethanol (10%) consumption and preference after 7 weeks and no difference in morphine (2 and 5mg/kg) conditioned place preference. No difference of preproenkephalin mRNA and mu opioid receptor levels was detected in the mesolimbic system between both groups. These data emphasize that human brief handling, which can lead to morphine dependence development, constitutes in itself an experimental treatment and not a control condition.

  17. Handling of Adolescent Rats Improves Learning and Memory and Decreases Anxiety

    PubMed Central

    Costa, Rafaela; Tamascia, Mariana L; Nogueira, Marie D; Casarini, Dulce E; Marcondes, Fernanda K

    2012-01-01

    Some environmental interventions can result in physiologic and behavioral changes in laboratory animals. In this context, the handling of adolescent or adult rodents has been reported to influence exploratory behavior and emotionality. Here we examined the effects of handling on memory and anxiety levels of adolescent rats. Male Sprague–Dawley rats (age, 60 d) were divided into a control group and a handled group, which were handled for 5 min daily, 5 d per week, for 6 wk. During handling bouts, the rat was removed from its cage, placed in the experimenter's lap or on the top of a table, and had its neck and back gently stroked by the experimenter's fingers. During week 6, each rat's anxiety level was evaluated in the elevated plus-maze (EPM) test. Learning and memory were evaluated 48 h later, by measuring escape latency in the elevated plus-maze test. Plasma corticosterone and catecholamine levels were measured also. Norepinephrine levels were lower in the handled rats compared with control animals, with no differences in epinephrine and corticosterone. As compared with the control rats, the handled rats showed increases in the percentage of time spent in the open arms of the test apparatus, percentage of entries into open arms, and number of visits to the end of the open arms and decreases in the latency of the first open arm entry. Escape latency was lower in the handled rats compared with control rats in both the first and second trials. The data obtained suggest that handling decreases anxiety levels and improves learning skills and memory in rats. PMID:23312082

  18. Staphylococcus xylosus PCR-validated Decontamination of Murine Individually Ventilated Cage Racks and Air Handling Units by Using ‘Active–Closed’ Exposure to Vaporized Hydrogen Peroxide

    PubMed Central

    Ragland, Natalie H; Miedel, Emily L; Gomez, Jose M; Engelman, Robert W

    2017-01-01

    Vaporized hydrogen peroxide (VHP) is used to decontaminate clinical, biocontainment, and research animal rooms and equipment. To assist with its implementation in a murine facility, we developed a safe and effective method of VHP sterilization of IVC racks and air handling units (AHU). Safety of VHP decontamination was assessed by ensuring VHP levels dissipated to less than 1 ppm in the room prior to personnel reentry and inside the primary enclosure prior to the return of mice; this condition occurred at least 18 h after the VHP cycle. Efficacy of VHP sterilization was assessed by using chemical indicators, biologic indicators, and PCR testing for Staphylococcus xylosus, a commensal organism of murine skin and an opportunistic pathogen, which was present in 160 of 172 (93%) of specimens from occupied IVC racks and the interior surfaces of in-use AHU. Neither mechanized washing nor hand-sanitizing eradicated S. xylosus from equipment airway interiors, with 17% to 24% of specimens remaining PCR-positive for S. xylosus. ‘Static–open’ VHP exposure of sanitized equipment did not ensure its sterilization. In contrast, ‘active–closed’ VHP exposure, in which IVC racks were assembled, sealed, and connected to AHU set to the VHP cycle, increased the proportion of chemical indicators that detected sterilizing levels of VHP inside the assembled equipment, and significantly decreased PCR-detectable S. xylosus inside the equipment. Supplementing bulk steam sterilization of the primary enclosure with VHP sterilization of the secondary housing equipment during room change-outs may help to mitigate opportunistic agents that jeopardize studies involving immunodeficient strains. PMID:29256369

  19. Tickling, a Technique for Inducing Positive Affect When Handling Rats.

    PubMed

    Cloutier, Sylvie; LaFollette, Megan R; Gaskill, Brianna N; Panksepp, Jaak; Newberry, Ruth C

    2018-05-08

    Handling small animals such as rats can lead to several adverse effects. These include the fear of humans, resistance to handling, increased injury risk for both the animals and the hands of their handlers, decreased animal welfare, and less valid research data. To minimize negative effects on experimental results and human-animal relationships, research animals are often habituated to being handled. However, the methods of habituation are highly variable and often of limited effectiveness. More potently, it is possible for humans to mimic aspects of the animals' playful rough-and-tumble behavior during handling. When applied to laboratory rats in a systematic manner, this playful handling, referred to as tickling, consistently gives rise to positive behavioral responses. This article provides a detailed description of a standardized rat tickling technique. This method can contribute to future investigations into positive affective states in animals, make it easier to handle rats for common husbandry activities such as cage changing or medical/research procedures such as injection, and be implemented as a source of social enrichment. It is concluded that this method can be used to efficiently and practicably reduce rats' fearfulness of humans and improve their welfare, as well as reliably model positive affective states.

  20. Quantifying the effect of editor-author relations on manuscript handling times.

    PubMed

    Sarigöl, Emre; Garcia, David; Scholtes, Ingo; Schweitzer, Frank

    2017-01-01

    In this article we study to what extent the academic peer review process is influenced by social relations between the authors of a manuscript and the editor handling the manuscript. Taking the open access journal PlosOne as a case study, our analysis is based on a data set of more than 100,000 articles published between 2007 and 2015. Using available data on handling editor, submission and acceptance time of manuscripts, we study the question whether co-authorship relations between authors and the handling editor affect the manuscript handling time , i.e. the time taken between the submission and acceptance of a manuscript. Our analysis reveals (1) that editors handle papers co-authored by previous collaborators significantly more often than expected at random, and (2) that such prior co-author relations are significantly related to faster manuscript handling. Addressing the question whether these shorter manuscript handling times can be explained by the quality of publications, we study the number of citations and downloads which accepted papers eventually accumulate. Moreover, we consider the influence of additional (social) factors, such as the editor's experience, the topical similarity between authors and editors, as well as reciprocal citation relations between authors and editors. Our findings show that, even when correcting for other factors like time, experience, and performance, prior co-authorship relations have a large and significant influence on manuscript handling times, speeding up the editorial decision on average by 19 days.