Sample records for hazard identification methods

  1. Identification of Potential Hazard using Hazard Identification and Risk Assessment

    NASA Astrophysics Data System (ADS)

    Sari, R. M.; Syahputri, K.; Rizkya, I.; Siregar, I.

    2017-03-01

    This research was conducted in the paper production’s company. These Paper products will be used as a cigarette paper. Along in the production’s process, Company provides the machines and equipment that operated by workers. During the operations, all workers may potentially injured. It known as a potential hazard. Hazard identification and risk assessment is one part of a safety and health program in the stage of risk management. This is very important as part of efforts to prevent occupational injuries and diseases resulting from work. This research is experiencing a problem that is not the identification of potential hazards and risks that would be faced by workers during the running production process. The purpose of this study was to identify the potential hazards by using hazard identification and risk assessment methods. Risk assessment is done using severity criteria and the probability of an accident. According to the research there are 23 potential hazard that occurs with varying severity and probability. Then made the determination Risk Assessment Code (RAC) for each potential hazard, and gained 3 extreme risks, 10 high risks, 6 medium risks and 3 low risks. We have successfully identified potential hazard using RAC.

  2. Hazard identification by methods of animal-based toxicology.

    PubMed

    Barlow, S M; Greig, J B; Bridges, J W; Carere, A; Carpy, A J M; Galli, C L; Kleiner, J; Knudsen, I; Koëter, H B W M; Levy, L S; Madsen, C; Mayer, S; Narbonne, J-F; Pfannkuch, F; Prodanchuk, M G; Smith, M R; Steinberg, P

    2002-01-01

    This paper is one of several prepared under the project "Food Safety In Europe: Risk Assessment of Chemicals in Food and Diet" (FOSIE), a European Commission Concerted Action Programme, organised by the International Life Sciences Institute, Europe (ILSI). The aim of the FOSIE project is to review the current state of the science of risk assessment of chemicals in food and diet, by consideration of the four stages of risk assessment, that is, hazard identification, hazard characterisation, exposure assessment and risk characterisation. The contribution of animal-based methods in toxicology to hazard identification of chemicals in food and diet is discussed. The importance of first applying existing technical and chemical knowledge to the design of safety testing programs for food chemicals is emphasised. There is consideration of the presently available and commonly used toxicity testing approaches and methodologies, including acute and repeated dose toxicity, reproductive and developmental toxicity, neurotoxicity, genotoxicity, carcinogenicity, immunotoxicity and food allergy. They are considered from the perspective of whether they are appropriate for assessing food chemicals and whether they are adequate to detect currently known or anticipated hazards from food. Gaps in knowledge and future research needs are identified; research on these could lead to improvements in the methods of hazard identification for food chemicals. The potential impact of some emerging techniques and toxicological issues on hazard identification for food chemicals, such as new measurement techniques, the use of transgenic animals, assessment of hormone balance and the possibilities for conducting studies in which common human diseases have been modelled, is also considered.

  3. Identification and assessment of hazardous compounds in drinking water.

    PubMed

    Fawell, J K; Fielding, M

    1985-12-01

    The identification of organic chemicals in drinking water and their assessment in terms of potential hazardous effects are two very different but closely associated tasks. In relation to both continuous low-level background contamination and specific, often high-level, contamination due to pollution incidents, the identification of contaminants is a pre-requisite to evaluation of significant hazards. Even in the case of the rapidly developing short-term bio-assays which are applied to water to indicate a potential genotoxic hazard (for example Ames tests), identification of the active chemicals is becoming a major factor in the further assessment of the response. Techniques for the identification of low concentrations of organic chemicals in drinking water have developed remarkably since the early 1970s and methods based upon gas chromatography-mass spectrometry (GC-MS) have revolutionised qualitative analysis of water. Such techniques are limited to "volatile" chemicals and these usually constitute a small fraction of the total organic material in water. However, in recent years there have been promising developments in techniques for "non-volatile" chemicals in water. Such techniques include combined high-performance liquid chromatography-mass spectrometry (HPLC-MS) and a variety of MS methods, involving, for example, field desorption, fast atom bombardment and thermospray ionisation techniques. In the paper identification techniques in general are reviewed and likely future developments outlined. The assessment of hazards associated with chemicals identified in drinking and related waters usually centres upon toxicology - an applied science which involves numerous disciplines. The paper examines the toxicological information needed, the quality and deployment of such information and discusses future research needs. Application of short-term bio-assays to drinking water is a developing area and one which is closely involved with, and to some extent dependent on, powerful methods of identification. Recent developments are discussed.

  4. Hazard Identification and Risk Assessment in Water Treatment Plant considering Environmental Health and Safety Practice

    NASA Astrophysics Data System (ADS)

    Falakh, Fajrul; Setiani, Onny

    2018-02-01

    Water Treatment Plant (WTP) is an important infrastructure to ensure human health and the environment. In its development, aspects of environmental safety and health are of concern. This paper case study was conducted at the Water Treatment Plant Company in Semarang, Central Java, Indonesia. Hazard identification and risk assessment is one part of the occupational safety and health program at the risk management stage. The purpose of this study was to identify potential hazards using hazard identification methods and risk assessment methods. Risk assessment is done using criteria of severity and probability of accident. The results obtained from this risk assessment are 22 potential hazards present in the water purification process. Extreme categories that exist in the risk assessment are leakage of chlorine and industrial fires. Chlorine and fire leakage gets the highest value because its impact threatens many things, such as industrial disasters that could endanger human life and the environment. Control measures undertaken to avoid potential hazards are to apply the use of personal protective equipment, but management will also be better managed in accordance with hazard control hazards, occupational safety and health programs such as issuing work permits, emergency response training is required, Very useful in overcoming potential hazards that have been determined.

  5. 10 CFR 851.21 - Hazard identification and assessment.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    .... Procedures must include methods to: (1) Assess worker exposure to chemical, physical, biological, or safety workplace hazards through appropriate workplace monitoring; (2) Document assessment for chemical, physical... hazards; (6) Perform routine job activity-level hazard analyses; (7) Review site safety and health...

  6. 10 CFR 851.21 - Hazard identification and assessment.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    .... Procedures must include methods to: (1) Assess worker exposure to chemical, physical, biological, or safety workplace hazards through appropriate workplace monitoring; (2) Document assessment for chemical, physical... hazards; (6) Perform routine job activity-level hazard analyses; (7) Review site safety and health...

  7. 10 CFR 851.21 - Hazard identification and assessment.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    .... Procedures must include methods to: (1) Assess worker exposure to chemical, physical, biological, or safety..., biological, and safety workplace hazards using recognized exposure assessment and testing methodologies and... hazards and the established controls within 90 days after identifying such hazards. The Head of DOE Field...

  8. 10 CFR 851.21 - Hazard identification and assessment.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    .... Procedures must include methods to: (1) Assess worker exposure to chemical, physical, biological, or safety..., biological, and safety workplace hazards using recognized exposure assessment and testing methodologies and... hazards and the established controls within 90 days after identifying such hazards. The Head of DOE Field...

  9. 10 CFR 851.21 - Hazard identification and assessment.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    .... Procedures must include methods to: (1) Assess worker exposure to chemical, physical, biological, or safety..., biological, and safety workplace hazards using recognized exposure assessment and testing methodologies and... hazards and the established controls within 90 days after identifying such hazards. The Head of DOE Field...

  10. Standoff detection: distinction of bacteria by hyperspectral laser induced fluorescence

    NASA Astrophysics Data System (ADS)

    Walter, Arne; Duschek, Frank; Fellner, Lea; Grünewald, Karin M.; Hausmann, Anita; Julich, Sandra; Pargmann, Carsten; Tomaso, Herbert; Handke, Jürgen

    2016-05-01

    Sensitive detection and rapid identification of hazardous bioorganic material with high sensitivity and specificity are essential topics for defense and security. A single method can hardly cover these requirements. While point sensors allow a highly specific identification, they only provide localized information and are comparatively slow. Laser based standoff systems allow almost real-time detection and classification of potentially hazardous material in a wide area and can provide information on how the aerosol may spread. The coupling of both methods may be a promising solution to optimize the acquisition and identification of hazardous substances. The capability of the outdoor LIF system at DLR Lampoldshausen test facility as an online classification tool has already been demonstrated. Here, we present promising data for further differentiation among bacteria. Bacteria species can express unique fluorescence spectra after excitation at 280 nm and 355 nm. Upon deactivation, the spectral features change depending on the deactivation method.

  11. Perception-based road hazard identification with Internet support.

    PubMed

    Tarko, Andrew P; DeSalle, Brian R

    2003-01-01

    One of the most important tasks faced by highway agencies is identifying road hazards. Agencies use crash statistics to detect road intersections and segments where the frequency of crashes is excessive. With the crash-based method, a dangerous intersection or segment can be pointed out only after a sufficient number of crashes occur. A more proactive method is needed, and motorist complaints may be able to assist agencies in detecting road hazards before crashes occur. This paper investigates the quality of safety information reported by motorists and the effectiveness of hazard identification based on motorist reports, which were collected with an experimental Internet website. It demonstrates that the intersections pointed out by motorists tended to have more crashes than other intersections. The safety information collected through the website was comparable to 2-3 months of crash data. It was concluded that although the Internet-based method could not substitute for the traditional crash-based methods, its joint use with crash statistics might be useful in detecting new hazards where crash data had been collected for a short time.

  12. Method and apparatus for identification of hazards along an intended travel route

    NASA Technical Reports Server (NTRS)

    Kronfeld, Kevin M. (Inventor); Lapis, Mary Beth (Inventor); Walling, Karen L. (Inventor); Chackalackal, Mathew S. (Inventor)

    2003-01-01

    Targets proximate to a travel route plan were evaluated to determine hazardousness. Projected geometric representation of a vehicle determines intrusion of hazardous targets along travel route plan. Geometric representation of hazardous targets projected along motion vector to determine intrusion upon travel route plan. Intrusion assessment presented on user display.

  13. Classification of Large-Scale Remote Sensing Images for Automatic Identification of Health Hazards: Smoke Detection Using an Autologistic Regression Classifier.

    PubMed

    Wolters, Mark A; Dean, C B

    2017-01-01

    Remote sensing images from Earth-orbiting satellites are a potentially rich data source for monitoring and cataloguing atmospheric health hazards that cover large geographic regions. A method is proposed for classifying such images into hazard and nonhazard regions using the autologistic regression model, which may be viewed as a spatial extension of logistic regression. The method includes a novel and simple approach to parameter estimation that makes it well suited to handling the large and high-dimensional datasets arising from satellite-borne instruments. The methodology is demonstrated on both simulated images and a real application to the identification of forest fire smoke.

  14. RESTORING HAZARDOUS SPILL-DAMAGED AREAS: TECHNIQUE IDENTIFICATION/ASSESSMENT

    EPA Science Inventory

    The goal of this study was to identify and assess methods that could be used to accelerate the restoration of lands damaged by spills of hazardous materials. The literature was reviewed to determine what response methods had been used in the past to clean up spills on land and id...

  15. Determination of atmospheric dilution for emergency preparedness: a joint EPA-DOE (Environmental Protection Agency-Department of Energy) technical workshop held on October 15-17, 1986

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rogers, S.E.

    1988-10-01

    This workshop was held in Research Triangle Park, NC in October of 1986. The objectives of the workshop were to review the current methods of determining atmospheric dilution for use in hazard identification, emergency-preparedness planning, and emergency response; to provide recommendations for choosing among these methods; and, finally, to define the role of the meteorologist in hazard identification, emergency planning, etc. Several invited papers were presented, and panel discussions were held to meet the objectives. The results are presented and discussed.

  16. Application of the FTA and ETA Method for Gas Hazard Identification for the Performance of Safety Systems in the Industrial Department

    NASA Astrophysics Data System (ADS)

    Ignac-Nowicka, Jolanta

    2018-03-01

    The paper analyzes the conditions of safe use of industrial gas systems and factors influencing gas hazards. Typical gas installation and its basic features have been characterized. The results of gas threat analysis in an industrial enterprise using FTA error tree method and ETA event tree method are presented. Compares selected methods of identifying hazards gas industry with respect to the scope of their use. The paper presents an analysis of two exemplary hazards: an industrial gas catastrophe (FTA) and an explosive gas explosion (ETA). In both cases, technical risks and human errors (human factor) were taken into account. The cause-effect relationships of hazards and their causes are presented in the form of diagrams in the drawings.

  17. Methods for assessment of stream-related hazards to highways and bridges.

    DOT National Transportation Integrated Search

    1981-03-01

    particular river reach, but also on the behavior of the entire fluvial system of which it is a part. Rivers are complex landforms. A simple and straight forward approach to the identification of river hazards is not always possible. A complete evalua...

  18. Seismic Hazard Assessment for a Characteristic Earthquake Scenario: Probabilistic-Deterministic Method

    NASA Astrophysics Data System (ADS)

    mouloud, Hamidatou

    2016-04-01

    The objective of this paper is to analyze the seismic activity and the statistical treatment of seismicity catalog the Constantine region between 1357 and 2014 with 7007 seismic event. Our research is a contribution to improving the seismic risk management by evaluating the seismic hazard in the North-East Algeria. In the present study, Earthquake hazard maps for the Constantine region are calculated. Probabilistic seismic hazard analysis (PSHA) is classically performed through the Cornell approach by using a uniform earthquake distribution over the source area and a given magnitude range. This study aims at extending the PSHA approach to the case of a characteristic earthquake scenario associated with an active fault. The approach integrates PSHA with a high-frequency deterministic technique for the prediction of peak and spectral ground motion parameters in a characteristic earthquake. The method is based on the site-dependent evaluation of the probability of exceedance for the chosen strong-motion parameter. We proposed five sismotectonique zones. Four steps are necessary: (i) identification of potential sources of future earthquakes, (ii) assessment of their geological, geophysical and geometric, (iii) identification of the attenuation pattern of seismic motion, (iv) calculation of the hazard at a site and finally (v) hazard mapping for a region. In this study, the procedure of the earthquake hazard evaluation recently developed by Kijko and Sellevoll (1992) is used to estimate seismic hazard parameters in the northern part of Algeria.

  19. A European perspective on alternatives to animal testing for environmental hazard identification and risk assessment.

    PubMed

    Scholz, Stefan; Sela, Erika; Blaha, Ludek; Braunbeck, Thomas; Galay-Burgos, Malyka; García-Franco, Mauricio; Guinea, Joaquin; Klüver, Nils; Schirmer, Kristin; Tanneberger, Katrin; Tobor-Kapłon, Marysia; Witters, Hilda; Belanger, Scott; Benfenati, Emilio; Creton, Stuart; Cronin, Mark T D; Eggen, Rik I L; Embry, Michelle; Ekman, Drew; Gourmelon, Anne; Halder, Marlies; Hardy, Barry; Hartung, Thomas; Hubesch, Bruno; Jungmann, Dirk; Lampi, Mark A; Lee, Lucy; Léonard, Marc; Küster, Eberhard; Lillicrap, Adam; Luckenbach, Till; Murk, Albertinka J; Navas, José M; Peijnenburg, Willie; Repetto, Guillermo; Salinas, Edward; Schüürmann, Gerrit; Spielmann, Horst; Tollefsen, Knut Erik; Walter-Rohde, Susanne; Whale, Graham; Wheeler, James R; Winter, Matthew J

    2013-12-01

    Tests with vertebrates are an integral part of environmental hazard identification and risk assessment of chemicals, plant protection products, pharmaceuticals, biocides, feed additives and effluents. These tests raise ethical and economic concerns and are considered as inappropriate for assessing all of the substances and effluents that require regulatory testing. Hence, there is a strong demand for replacement, reduction and refinement strategies and methods. However, until now alternative approaches have only rarely been used in regulatory settings. This review provides an overview on current regulations of chemicals and the requirements for animal tests in environmental hazard and risk assessment. It aims to highlight the potential areas for alternative approaches in environmental hazard identification and risk assessment. Perspectives and limitations of alternative approaches to animal tests using vertebrates in environmental toxicology, i.e. mainly fish and amphibians, are discussed. Free access to existing (proprietary) animal test data, availability of validated alternative methods and a practical implementation of conceptual approaches such as the Adverse Outcome Pathways and Integrated Testing Strategies were identified as major requirements towards the successful development and implementation of alternative approaches. Although this article focusses on European regulations, its considerations and conclusions are of global relevance. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. 49 CFR 178.60 - Specification 8AL steel cylinders with porous fillings for acetylene.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS... appendix A to this part. (c) Identification of steel. Material must be identified by any suitable method..., specified in paragraph (f)(1) of this section, of similar material which have been previously welded or...

  1. 40 CFR 63.5 - Preconstruction review and notification requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) [Reserved] (H) The type and quantity of hazardous air pollutants emitted by the source, reported in units... actual emissions data are not yet available, an estimate of the type and quantity of hazardous air..., operating design capacity, and method of operation of the source, including an identification of each type...

  2. Training Medical Students about Hazardous Drinking Using Simple Assessment Techniques

    ERIC Educational Resources Information Center

    Hidalgo, Jesús López-Torres; Pretel, Fernando Andrés; Bravo, Beatriz Navarro; Rabadan, Francisco Escobar; Serrano Selva, Juan Pedro; Latorre Postigo, Jose Miguel; Martínez, Ignacio Párraga

    2014-01-01

    Objective: To examine the ability of medical students to identify hazardous drinkers using screening tools recommended in clinical practice. Design: Observational cross-sectional study. Setting: Faculty of Medicine of Castilla-La Mancha, Spain. Method: The medical students learnt to use Alcohol Use Disorders Identification Test (AUDIT) and…

  3. NANOSTRUCTURED PLANAR WAVEGUIDE DEVICE FOR MOLECULAR IDENTIFICATION OF HAZARDOUS COMPOUNDS IN WATER BY EVANESCENT SURFACE ENHANCED RAMAN SPECTROSCOPY - PHASE I

    EPA Science Inventory

    Senspex, Inc. proposes to investigate a novel diagnostic tool based upon evanescent field planar waveguide sensing and complementary nanostructured mediated molecular vibration spectroscopy methods for rapid detection and analysis of hazardous biological and chemical targets i...

  4. RCRA, superfund and EPCRA hotline training module. Introduction to: Hazardous waste identification (40 cfr part 261) updated July 1996

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-07-01

    The module introduces a specific hazardous waste identification process, which involves asking and analyzing a series of questions about any waste being evaluated. It analyzes in detail the Resource Conservation and Recovery Act (RCRA) definition of `hazardous waste.` It explains concepts that are essential to identifying a RCRA hazardous waste: hazardous waste listing, hazardous waste characteristics, the `mixture` and `derived-from` rules, the `contained-in` policy, and the hazardous waste identification rules (HWIR).

  5. Comparison of Unmanned Aerial Vehicle Technology Versus Standard Practice in Identification of Hazards at a Mass Casualty Incident Scenario by Primary Care Paramedic Students.

    PubMed

    Jain, Trevor; Sibley, Aaron; Stryhn, Henrik; Hubloue, Ives

    2018-01-31

    Introduction The proliferation of unmanned aerial vehicles (UAV) has the potential to change the situational awareness of incident commanders allowing greater scene safety. The aim of this study was to compare UAV technology to standard practice (SP) in hazard identification during a simulated multi-vehicle motor collision (MVC) in terms of time to identification, accuracy and the order of hazard identification. A prospective observational cohort study was conducted with 21 students randomized into UAV or SP group, based on a MVC with 7 hazards. The UAV group remained at the UAV ground station while the SP group approached the scene. After identifying hazards the time and order was recorded. The mean time (SD, range) to identify the hazards were 3 minutes 41 seconds (1 minute 37 seconds, 1 minute 48 seconds-6 minutes 51 seconds) and 2 minutes 43 seconds (55 seconds, 1 minute 43 seconds-4 minutes 38 seconds) in UAV and SP groups corresponding to a mean difference of 58 seconds (P=0.11). A non-parametric permutation test showed a significant (P=0.04) difference in identification order. Both groups had 100% accuracy in hazard identification with no statistical difference in time for hazard identification. A difference was found in the identification order of hazards. (Disaster Med Public Health Preparedness. 2018;page 1 of 4).

  6. Applicability of the Common Safety Method for Risk Evaluation and Assessment (CSM-RA) to the Space Domain

    NASA Astrophysics Data System (ADS)

    Moreira, Francisco; Silva, Nuno

    2016-08-01

    Safety systems require accident avoidance. This is covered by application standards, processes, techniques and tools that support the identification, analysis, elimination or reduction to an acceptable level of system risks and hazards. Ideally, a safety system should be free of hazards. However, both industry and academia have been struggling to ensure appropriate risk and hazard analysis, especially in what concerns completeness of the hazards, formalization, and timely analysis in order to influence the specifications and the implementation. Such analysis is also important when considering a change to an existing system. The Common Safety Method for Risk Evaluation and Assessment (CSM- RA) is a mandatory procedure whenever any significant change is proposed to the railway system in a European Member State. This paper provides insights on the fundamentals of CSM-RA based and complemented with Hazard Analysis. When and how to apply them, and the relation and similarities of these processes with industry standards and the system life cycles is highlighted. Finally, the paper shows how CSM-RA can be the basis of a change management process, guiding the identification and management of the hazards helping ensuring the similar safety level as the initial system. This paper will show how the CSM-RA principles can be used in other domains particularly for space system evolution.

  7. INTERAGENCY PROGRAM IN ENERGY-RELATED HEALTH AND ENVIRONMENTAL EFFECTS RESEARCH. PROJECT STATUS REPORT

    EPA Science Inventory

    Projects reported in this document are grouped under one of four major research areas. The first area is identification of hazardous agents associated with non-nuclear energy technologies. These projects involved the development of qualitative methods for the identification of ha...

  8. Vulnerabilities, Influences and Interaction Paths: Failure Data for Integrated System Risk Analysis

    NASA Technical Reports Server (NTRS)

    Malin, Jane T.; Fleming, Land

    2006-01-01

    We describe graph-based analysis methods for identifying and analyzing cross-subsystem interaction risks from subsystem connectivity information. By discovering external and remote influences that would be otherwise unexpected, these methods can support better communication among subsystem designers at points of potential conflict and to support design of more dependable and diagnosable systems. These methods identify hazard causes that can impact vulnerable functions or entities if propagated across interaction paths from the hazard source to the vulnerable target. The analysis can also assess combined impacts of And-Or trees of disabling influences. The analysis can use ratings of hazards and vulnerabilities to calculate cumulative measures of the severity and importance. Identification of cross-subsystem hazard-vulnerability pairs and propagation paths across subsystems will increase coverage of hazard and risk analysis and can indicate risk control and protection strategies.

  9. RCRA/UST, superfund and EPCRA hotline training module. Introduction to: Hazardous waste identification (40 CFR part 261) updated as of July 1995

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1995-11-01

    This module introduces a specific hazardous waste identification process, which involves asking and analyzing a series of questions about any waste being evaluated. Analyzes in detail the Resource Conservation and Recovery Act (RCRA) definition of hazardous waste. It explains the following concepts that are essential to identifying a RCRA hazardous waste: hazardous waste listing, hazardous waste characteristics, the mixture and derived-from rules, the contained-in policy, and the Hazardous Waste Identification Rule (HWIR).

  10. 76 FR 55846 - Hazardous Waste Management System: Identification and Listing of Hazardous Waste: Carbon Dioxide...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-09

    ... 2050-AG60 Hazardous Waste Management System: Identification and Listing of Hazardous Waste: Carbon... hazardous waste management under the Resource Conservation and Recovery Act (RCRA) to conditionally exclude... and recordkeeping requirements. 40 CFR Part 261 Environmental protection, Hazardous waste, Solid waste...

  11. Rapid method for sampling metals for materials identification

    NASA Technical Reports Server (NTRS)

    Higgins, L. E.

    1971-01-01

    Nondamaging process similar to electrochemical machining is useful in obtaining metal samples from places inaccessible to conventional sampling methods or where methods would be hazardous or contaminating to specimens. Process applies to industries where metals or metal alloys play a vital role.

  12. 48 CFR 252.223-7001 - Hazard warning labels.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...

  13. 48 CFR 252.223-7001 - Hazard warning labels.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...

  14. 48 CFR 252.223-7001 - Hazard warning labels.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...

  15. 48 CFR 252.223-7001 - Hazard warning labels.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...

  16. 48 CFR 252.223-7001 - Hazard warning labels.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...

  17. Preliminary hazards analysis -- vitrification process

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Coordes, D.; Ruggieri, M.; Russell, J.

    1994-06-01

    This paper presents a Preliminary Hazards Analysis (PHA) for mixed waste vitrification by joule heating. The purpose of performing a PHA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PHA is then followed by a Preliminary Safety Analysis Report (PSAR) performed during Title 1 and 2 design. The PSAR then leads to performance of the Final Safety Analysis Report performed during the facility`s constructionmore » and testing. It should be completed before routine operation of the facility commences. This PHA addresses the first four chapters of the safety analysis process, in accordance with the requirements of DOE Safety Guidelines in SG 830.110. The hazards associated with vitrification processes are evaluated using standard safety analysis methods which include: identification of credible potential hazardous energy sources; identification of preventative features of the facility or system; identification of mitigative features; and analyses of credible hazards. Maximal facility inventories of radioactive and hazardous materials are postulated to evaluate worst case accident consequences. These inventories were based on DOE-STD-1027-92 guidance and the surrogate waste streams defined by Mayberry, et al. Radiological assessments indicate that a facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous materials assessment indicates that a Mixed Waste Vitrification facility will be a Low Hazard facility having minimal impacts to offsite personnel and the environment.« less

  18. Native Fluorescence Detection Methods and Detectors for Naphthalene and/or Other Volatile Organic Compound Vapors

    NASA Technical Reports Server (NTRS)

    Hug, William F. (Inventor); Bhartia, Rohit (Inventor); Reid, Ray D. (Inventor); Lane, Arthur L. (Inventor)

    2014-01-01

    Naphthalene, benzene, toluene, xylene, and other volatile organic compounds have been identified as serious health hazards. This is especially true for personnel working with JP8 jet fuel and other fuels containing naphthalene as well as other hazardous volatile organic compounds (VOCs). Embodiments of the invention are directed to methods and apparatus for near-real-time in-situ detection and accumulated dose measurement of exposure to naphthalene vapor and other hazardous gaseous VOCs. The methods and apparatus employ excitation of fluorophors native or endogenous to compounds of interest using light sources emitting in the ultraviolet below 300 nm and measurement of native fluorescence emissions in distinct wavebands above the excitation wavelength. The apparatus of some embodiments are cell-phone-sized sensor/dosimeter "badges" to be worn by personnel potentially exposed to naphthalene or other hazardous VOCs. The badge sensor of some embodiments provides both real time detection and data logging of exposure to naphthalene or other VOCs of interest from which both instantaneous and accumulated dose can be determined. The badges employ a new native fluorescence based detection method to identify and differentiate VOCs. The particular focus of some embodiments are the detection and identification of naphthalene while other embodiments are directed to detection and identification of other VOCs like aromatic hydrocarbons such as benzene, toluene, and xylene.

  19. 75 FR 58346 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... Chemical Company-Texas Operations (Eastman) to exclude (or delist) certain solid wastes generated by its Longview, Texas, facility from the lists of hazardous wastes. EPA used the Delisting Risk Assessment... Waste Management System; Identification and Listing of Hazardous Waste AGENCY: Environmental Protection...

  20. 40 CFR 241.3 - Standards and procedures for identification of non-hazardous secondary materials that are solid...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... identification of non-hazardous secondary materials that are solid wastes when used as fuels or ingredients in...) SOLID WASTES SOLID WASTES USED AS FUELS OR INGREDIENTS IN COMBUSTION UNITS Identification of Non-Hazardous Secondary Materials That Are Solid Wastes When Used as Fuels or Ingredients in Combustion Units...

  1. Collection and Extraction of Occupational Air Samples for Analysis of Fungal DNA.

    PubMed

    Lemons, Angela R; Lindsley, William G; Green, Brett J

    2018-05-02

    Traditional methods of identifying fungal exposures in occupational environments, such as culture and microscopy-based approaches, have several limitations that have resulted in the exclusion of many species. Advances in the field over the last two decades have led occupational health researchers to turn to molecular-based approaches for identifying fungal hazards. These methods have resulted in the detection of many species within indoor and occupational environments that have not been detected using traditional methods. This protocol details an approach for determining fungal diversity within air samples through genomic DNA extraction, amplification, sequencing, and taxonomic identification of fungal internal transcribed spacer (ITS) regions. ITS sequencing results in the detection of many fungal species that are either not detected or difficult to identify to species level using culture or microscopy. While these methods do not provide quantitative measures of fungal burden, they offer a new approach to hazard identification and can be used to determine overall species richness and diversity within an occupational environment.

  2. The hazards of hazard identification in environmental epidemiology.

    PubMed

    Saracci, Rodolfo

    2017-08-09

    Hazard identification is a major scientific challenge, notably for environmental epidemiology, and is often surrounded, as the recent case of glyphosate shows, by debate arising in the first place by the inherently problematic nature of many components of the identification process. Particularly relevant in this respect are components less amenable to logical or mathematical formalization and essentially dependent on scientists' judgment. Four such potentially hazardous components that are capable of distorting the correct process of hazard identification are reviewed and discussed from an epidemiologist perspective: (1) lexical mix-up of hazard and risk (2) scientific questions as distinct from testable hypotheses, and implications for the hierarchy of strength of evidence obtainable from different types of study designs (3) assumptions in prior beliefs and model choices and (4) conflicts of interest. Four suggestions are put forward to strengthen a process that remains in several aspects judgmental, but not arbitrary, in nature.

  3. 75 FR 60689 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Proposed Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-01

    ... exclude (or delist) a certain solid waste generated by its Beaumont, Texas, facility from the lists of hazardous wastes. EPA used the Delisting Risk Assessment Software (DRAS) Version 3.0 in the evaluation of... Waste Management System; Identification and Listing of Hazardous Waste; Proposed Rule AGENCY...

  4. Extended GTST-MLD for aerospace system safety analysis.

    PubMed

    Guo, Chiming; Gong, Shiyu; Tan, Lin; Guo, Bo

    2012-06-01

    The hazards caused by complex interactions in the aerospace system have become a problem that urgently needs to be settled. This article introduces a method for aerospace system hazard interaction identification based on extended GTST-MLD (goal tree-success tree-master logic diagram) during the design stage. GTST-MLD is a functional modeling framework with a simple architecture. Ontology is used to extend the ability of system interaction description in GTST-MLD by adding the system design knowledge and the past accident experience. From the level of functionality and equipment, respectively, this approach can help the technician detect potential hazard interactions. Finally, a case is used to show the method. © 2011 Society for Risk Analysis.

  5. Novel Methods at Molecular Level for Neurotoxicity Testing in 21st Century-Utility of Structure-Activity Relationship

    EPA Science Inventory

    Current neurotoxicity and developmental neurotoxicity testing methods for hazard identification rely on in vivo neurobehavior, neurophysiological, and gross pathology of the nervous system. These measures may not be sensitive enough to detect small changes caused by realistic ex...

  6. Job safety analysis and hazard identification for work accident prevention in para rubber wood sawmills in southern Thailand

    PubMed Central

    Thepaksorn, Phayong; Thongjerm, Supawan; Incharoen, Salee; Siriwong, Wattasit; Harada, Kouji; Koizumi, Akio

    2017-01-01

    Objective: We utilized job safety analysis (JSA) and hazard identification for work accident prevention in Para rubber wood sawmills, which aimed to investigate occupational health risk exposures and assess the health hazards at sawmills in the Trang Province, located in southern Thailand. Methods: We conducted a cross-sectional study which included a walk-through survey, JSA, occupational risk assessment, and environmental samplings from March through September 2015 at four Para rubber wood sawmills. Results: We identified potential occupational safety and health hazards associated with six main processes, including: 1) logging and cutting, 2) sawing the lumber into sheets, 3) planing and re-arranging, 4) vacuuming and wood preservation, 5) drying and planks re-arranging, and 6) grading, packing, and storing. Working in sawmills was associated with high risk of wood dust and noise exposure, occupational accidents injuring hands and feet, chemicals and fungicide exposure, and injury due to poor ergonomics or repetitive work. Discussion: Several high-risk areas were identified from JSA and hazard identification of the working processes, especially high wood dust and noise exposure when sawing lumber into sheets and risk of occupational accidents of the hands and feet when struck by lumber. All workers were strongly recommended to use personal protective equipment in any working processes. Exposures should be controlled using local ventilation systems and reducing noise transmission. We recommend that the results from the risk assessment performed in this study be used to create an action plan for reducing occupational health hazards in Para rubber sawmills. PMID:28993571

  7. 76 FR 63252 - Hazardous and Solid Waste Management System: Identification and Listing of Special Wastes...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ...-2011-0392; FRL-9476-6] RIN 2050-AE81 Hazardous and Solid Waste Management System: Identification and... Protection Agency (Agency or EPA) in conjunction with the proposed rule: Hazardous and Solid Waste Management...-0392. (4) Mail: Send two copies of your comments to Hazardous and Solid Waste Management System...

  8. Novel Methods at Molecular Level for Developmental Neurotoxicity Testing in 21st Century-Utility of Structure-Activity Relationship

    EPA Science Inventory

    Current neurotoxicity and developmental neurotoxicity testing methods for hazard identification rely on in vivo neurobehavior, neurophysiological, and gross pathology of the nervous system. These measures may not be sensitive enough to detect small changes caused by realistic ex...

  9. DEVELOPMENT OF AN IDENTIFICATION KIT FOR SPILLED HAZARDOUS MATERIALS

    EPA Science Inventory

    The Chemical Systems Laboratory (CSL) has developed a field kit to identify spilled hazardous materials in inland waters and on the ground. The Hazardous Materials Spills Identification Kit is a two-component kit consisting of an inverter/shortwave UV lamp unit for photochemical ...

  10. Aquatic Toxicity Screening of an ACWA Secondary Waste, GB-Hydrolysate

    DTIC Science & Technology

    2009-01-01

    Toxicity Comparison for GB-hydrolysates, Acetone, and Malathion Using O’Bryan and Ross Chemical Scoring System for Hazard and Exposure Identification ...hydrolysates, Acetone, and Malathion Using O’Bryan and Ross Chemical Scoring System for Hazard and Exposure Identification (5) and the U.S. Fish and...WWTF) or a TSDF. The toxicity results were ranked using the Chemical Scoring System for Hazard and Exposure Identification (5). This system is

  11. 40 CFR 263.11 - EPA identification number.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 27 2013-07-01 2013-07-01 false EPA identification number. 263.11... (CONTINUED) STANDARDS APPLICABLE TO TRANSPORTERS OF HAZARDOUS WASTE General § 263.11 EPA identification number. (a) A transporter must not transport hazardous wastes without having received an EPA...

  12. 40 CFR 263.11 - EPA identification number.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 27 2012-07-01 2012-07-01 false EPA identification number. 263.11... (CONTINUED) STANDARDS APPLICABLE TO TRANSPORTERS OF HAZARDOUS WASTE General § 263.11 EPA identification number. (a) A transporter must not transport hazardous wastes without having received an EPA...

  13. 40 CFR 263.11 - EPA identification number.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false EPA identification number. 263.11... (CONTINUED) STANDARDS APPLICABLE TO TRANSPORTERS OF HAZARDOUS WASTE General § 263.11 EPA identification number. (a) A transporter must not transport hazardous wastes without having received an EPA...

  14. 40 CFR 263.11 - EPA identification number.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 26 2014-07-01 2014-07-01 false EPA identification number. 263.11... (CONTINUED) STANDARDS APPLICABLE TO TRANSPORTERS OF HAZARDOUS WASTE General § 263.11 EPA identification number. (a) A transporter must not transport hazardous wastes without having received an EPA...

  15. 40 CFR 263.11 - EPA identification number.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 26 2011-07-01 2011-07-01 false EPA identification number. 263.11... (CONTINUED) STANDARDS APPLICABLE TO TRANSPORTERS OF HAZARDOUS WASTE General § 263.11 EPA identification number. (a) A transporter must not transport hazardous wastes without having received an EPA...

  16. Chemotaxonomic identification of single bacteria by micro-Raman spectroscopy: application to clean-room-relevant biological contaminations.

    PubMed

    Rösch, Petra; Harz, Michaela; Schmitt, Michael; Peschke, Klaus-Dieter; Ronneberger, Olaf; Burkhardt, Hans; Motzkus, Hans-Walter; Lankers, Markus; Hofer, Stefan; Thiele, Hans; Popp, Jürgen

    2005-03-01

    Microorganisms, such as bacteria, which might be present as contamination inside an industrial food or pharmaceutical clean room process need to be identified on short time scales in order to minimize possible health hazards as well as production downtimes causing financial deficits. Here we describe the first results of single-particle micro-Raman measurements in combination with a classification method, the so-called support vector machine technique, allowing for a fast, reliable, and nondestructive online identification method for single bacteria.

  17. Chemotaxonomic Identification of Single Bacteria by Micro-Raman Spectroscopy: Application to Clean-Room-Relevant Biological Contaminations

    PubMed Central

    Rösch, Petra; Harz, Michaela; Schmitt, Michael; Peschke, Klaus-Dieter; Ronneberger, Olaf; Burkhardt, Hans; Motzkus, Hans-Walter; Lankers, Markus; Hofer, Stefan; Thiele, Hans; Popp, Jürgen

    2005-01-01

    Microorganisms, such as bacteria, which might be present as contamination inside an industrial food or pharmaceutical clean room process need to be identified on short time scales in order to minimize possible health hazards as well as production downtimes causing financial deficits. Here we describe the first results of single-particle micro-Raman measurements in combination with a classification method, the so-called support vector machine technique, allowing for a fast, reliable, and nondestructive online identification method for single bacteria. PMID:15746368

  18. Integrated Decision Strategies for Skin Sensitization Hazard

    EPA Science Inventory

    One of the top priorities of the Interagency Coordinating Committee for the Validation of Alternative Methods (ICCVAM) is the identification and evaluation of non-animal alternatives for skin sensitization testing. Although skin sensitization is a complex process, the key biologi...

  19. NEUROBEHAVIORAL METHODS USED IN NEUROTOXICOLOGICAL RESEARCH

    EPA Science Inventory

    Exposure to chemicals in the environment and workplace can have adverse effects on the nervous system. ehavioral endpoints are being used with greater frequency in the hazard identification phase of neurotoxicology risk assessment. ne reason behavioral procedures are used in anim...

  20. Arsenic in Drinking Water-A Global Environmental Problem

    ERIC Educational Resources Information Center

    Wang, Joanna Shaofen; Wai, Chien M.

    2004-01-01

    Information on the worldwide occurrence of groundwater pollution by arsenic, the ensuing health hazards, and the debatable government regulations of arsenic in drinking water, is presented. Diagnostic identification of arsenic, and methods to eliminate it from water are also discussed.

  1. Perspectives on pathway perturbation: Focused research to enhance 3R objectives

    EPA Science Inventory

    In vitro high-throughput screening (HTS) and in silico technologies are emerging as 21st century tools for hazard identification. Computational methods that strategically examine cross-species conservation of protein sequence/structural information for chemical molecular targets ...

  2. Research on geological hazard identification based on deep learning

    NASA Astrophysics Data System (ADS)

    Zhu, Cheng; Cheng, Tao

    2018-05-01

    Geological hazards such as landslides, debris flows and collapses are potential hazards affecting the safety of nearby roads and people. Land and Resources Bureau and other relevant departments to undertake the responsibility of prevention and control of geological disasters, an important body, how to deal with the characteristics of sudden geological disasters in the region, according to pre-established emergency measures quickly and accurately survey, is an important issue to be solved. Based on the analysis of the types and effects of typical geological disasters, this paper studies the relevant methods of identifying typical geological disasters through artificial neural networks, and proposes and designs intelligent geological survey methods and systems based on deep learning to provide relevant departments such as Land and Resources Bureau Related Mountain Geological Survey and Information Support.

  3. 33 CFR 154.1228 - Methods of ensuring the availability of response resources by contract or other approved means.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... TRANSFERRING OIL OR HAZARDOUS MATERIAL IN BULK Response Plans for Animal Fats and Vegetable Oils Facilities... following methods: (1) The identification of an oil spill removal organization with specified equipment and... personnel, equipment, and services capable of being provided by the oil spill removal organization within...

  4. 33 CFR 154.1228 - Methods of ensuring the availability of response resources by contract or other approved means.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... TRANSFERRING OIL OR HAZARDOUS MATERIAL IN BULK Response Plans for Animal Fats and Vegetable Oils Facilities... following methods: (1) The identification of an oil spill removal organization with specified equipment and... personnel, equipment, and services capable of being provided by the oil spill removal organization within...

  5. Prevention of Major Accident Hazards (MAHs) in major Hazard Installation (MHI) premises via land use planning (LUP): a review

    NASA Astrophysics Data System (ADS)

    Khudbiddin, M. Q.; Rashid, Z. A.; Yeong, A. F. M. S.; Alias, A. B.; Irfan, M. F.; Fuad, M.; Hayati, H.

    2018-03-01

    For a number of years, there is a concern about the causes of major hazards, their identification, risk assessment and the process of its management from the global perspective on the activities of the industries due to the protection of the environment, human and property. Though, industries cannot take pleasure in their business by harming the nature of the land, there are a number of measures that need to be put into consideration by the industries. Such measures are in terms of management and safety for the businesses, lives, properties, as well as the environment. The lack of consideration in the selected appropriate criteria can result in major accidental hazards (MAHs). This paper will review the land use planning (LUP) methods used in the past and present to prevent major accident hazards at major hazard installation (MHI).

  6. Geomorphological hazards and environmental impact: Assessment and mapping

    NASA Astrophysics Data System (ADS)

    Panizza, Mario

    In five sections the author develops the methods for the integration of geomorphological concepts into Environmental Impact and Mapping. The first section introduces the concepts of Impact and Risk through the relationships between Geomorphological Environment and Anthropical Element. The second section proposes a methodology for the determination of Geomorphological Hazard and the identification of Geomorphological Risk. The third section synthesizes the procedure for the compilation of a Geomorphological Hazards Map. The fourth section outlines the concepts of Geomorphological Resource Assessment for the analysis of the Environmental Impact. The fifth section considers the contribution of geomorphological studies and mapping in the procedure for Environmental Impact Assessment.

  7. Implementation of hazard analysis and critical control point (HACCP) in dried anchovy production process

    NASA Astrophysics Data System (ADS)

    Citraresmi, A. D. P.; Wahyuni, E. E.

    2018-03-01

    The aim of this study was to inspect the implementation of Hazard Analysis and Critical Control Point (HACCP) for identification and prevention of potential hazards in the production process of dried anchovy at PT. Kelola Mina Laut (KML), Lobuk unit, Sumenep. Cold storage process is needed in each anchovy processing step in order to maintain its physical and chemical condition. In addition, the implementation of quality assurance system should be undertaken to maintain product quality. The research was conducted using a survey method, by following the whole process of making anchovy from the receiving raw materials to the packaging of final product. The method of data analysis used was descriptive analysis method. Implementation of HACCP at PT. KML, Lobuk unit, Sumenep was conducted by applying Pre Requisite Programs (PRP) and preparation stage consisting of 5 initial stages and 7 principles of HACCP. The results showed that CCP was found in boiling process flow with significant hazard of Listeria monocytogenesis bacteria and final sorting process with significant hazard of foreign material contamination in the product. Actions taken were controlling boiling temperature of 100 – 105°C for 3 - 5 minutes and training for sorting process employees.

  8. Neuronal models for evaluation of proliferation in vitro using high content screening

    EPA Science Inventory

    In vitro test methods can provide a rapid approach for the screening of large numbers of chemicals for their potential to produce toxicity (hazard identification). In order to identify potential developmental neurotoxicants, a battery of in vitro tests for neurodevelopmental proc...

  9. Method for Determining the Coalbed Methane Content with Determination the Uncertainty of Measurements

    NASA Astrophysics Data System (ADS)

    Szlązak, Nikodem; Korzec, Marek

    2016-06-01

    Methane has a bad influence on safety in underground mines as it is emitted to the air during mining works. Appropriate identification of methane hazard is essential to determining methane hazard prevention methods, ventilation systems and methane drainage systems. Methane hazard is identified while roadways are driven and boreholes are drilled. Coalbed methane content is one of the parameters which is used to assess this threat. This is a requirement according to the Decree of the Minister of Economy dated 28 June 2002 on work safety and hygiene, operation and special firefighting protection in underground mines. For this purpose a new method for determining coalbed methane content in underground coal mines has been developed. This method consists of two stages - collecting samples in a mine and testing the sample in the laboratory. The stage of determining methane content in a coal sample in a laboratory is essential. This article presents the estimation of measurement uncertainty of determining methane content in a coal sample according to this methodology.

  10. 48 CFR 23.302 - Policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... (Material Safety Data Sheet, Preparation and Submission of) includes criteria for identification of... WORKPLACE Hazardous Material Identification and Material Safety Data 23.302 Policy. (a) The Occupational.... Accordingly, offerors and contractors are required to submit hazardous materials data whenever the supplies...

  11. 48 CFR 23.302 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (Material Safety Data Sheet, Preparation and Submission of) includes criteria for identification of... WORKPLACE Hazardous Material Identification and Material Safety Data 23.302 Policy. (a) The Occupational.... Accordingly, offerors and contractors are required to submit hazardous materials data whenever the supplies...

  12. ASSESSING THE EFFECTS OF DICHLOROACETIC ACID (DCA) USING A MULTI-ENDPOINT MEDAKA ASSAY

    EPA Science Inventory

    In regulating the safety of water, EPA makes decisions on what chemical contaminants to regulate and at what levels. To make these decisions, the EPA needs hazard identification and dose-response information. Current rodent methods for generating required information have limita...

  13. USE OF RFID TO TRACK HAZARDOUS WASTE SHIPMENTS ACROSS DOMESTIC AND INTERNATIONAL BORDERS

    EPA Science Inventory

    Radio-frequency identification system (RFID) is an emerging commodity tracking technology that is being tested and implemented in a large number of applications worldwide. RFID is a method of transmitting data using radio waves, usually through communication with a tag. Both ac...

  14. USE OF EXISTING DATABASES FOR THE PURPOSE OF HAZARD IDENTIFICATION: AN EXAMPLE

    EPA Science Inventory

    Keywords: existing databases, hazard identification, cancer mortality, birth malformations

    Background: Associations between adverse health effects and environmental exposures are difficult to study, because exposures may be widespread, low-dose in nature, and common thro...

  15. Assessment of chemical effects on neurite outgrowth in PC12 cells using high content screening

    EPA Science Inventory

    Identification of chemicals that pose a hazard to the developing nervous system is the first step in reducing human exposure and preventing health risks to infants and children. In response to the need for more efficient methods to identify potential developmental neurotoxicants,...

  16. Application of LANDSAT data to delimitation of avalanche hazards in Montane Colorado

    NASA Technical Reports Server (NTRS)

    Knepper, D. H., Jr. (Principal Investigator)

    1977-01-01

    The author has identified the following significant results. Many avalanche hazard zones can be identified on LANDSAT imagery, but not consistently over a large region. Therefore, regional avalanche hazard mapping, using LANDSAT imagery, must draw on additional sources of information. A method was devised that depicts three levels of avalanche hazards according to three corresponding levels of certainty that active avalanches occur. The lowest level, potential avalanche hazards, was defined by delineating slopes steep enough to support avalanches at elevations where snowfall was likely to be sufficient to produce a thick snowpack. The intermediate level of avalanche hazard was interpreted as avalanche hazard zones. These zones have direct and indirect indicators of active avalanche activity and were interpreted from LANDSAT imagery. The highest level of known or active avalanche hazards was compiled from existing maps. Some landslides in Colorado were identified and, to a degree, delimited on LANDSAT imagery, but the conditions of their identification were highly variable. Because of local topographic, geologic, structural, and vegetational variations, there was no unique landslide spectral appearance.

  17. Decreased pain sensitivity due to trimethylbenzene exposure: case study on quantitative approaches for hazard identification

    EPA Science Inventory

    Traditionally, human health risk assessments have relied on qualitative approaches for hazard identification, often using the Hill criteria and weight of evidence determinations to integrate data from multiple studies. Recently, the National Research Council has recommended the ...

  18. 21 CFR 120.7 - Hazard analysis.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Hazard analysis. 120.7 Section 120.7 Food and... hazards. The written hazard analysis shall consist of at least the following: (1) Identification of food..., including food hazards that can occur before, during, and after harvest. The hazard analysis shall be...

  19. 21 CFR 120.7 - Hazard analysis.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Hazard analysis. 120.7 Section 120.7 Food and... hazards. The written hazard analysis shall consist of at least the following: (1) Identification of food..., including food hazards that can occur before, during, and after harvest. The hazard analysis shall be...

  20. 21 CFR 120.7 - Hazard analysis.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Hazard analysis. 120.7 Section 120.7 Food and... hazards. The written hazard analysis shall consist of at least the following: (1) Identification of food..., including food hazards that can occur before, during, and after harvest. The hazard analysis shall be...

  1. 21 CFR 120.7 - Hazard analysis.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Hazard analysis. 120.7 Section 120.7 Food and... hazards. The written hazard analysis shall consist of at least the following: (1) Identification of food..., including food hazards that can occur before, during, and after harvest. The hazard analysis shall be...

  2. 40 CFR 270.25 - Specific part B information requirements for equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... requirements for equipment. 270.25 Section 270.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... subpart BB of part 264 applies: (1) Equipment identification number and hazardous waste management unit identification. (2) Approximate locations within the facility (e.g., identify the hazardous waste management unit...

  3. CHARACTERIZATION OF A LOSS OF HETEROZYGOSITY CANCER HAZARD IDENTIFICATION ASSAY.

    EPA Science Inventory

    Tumor development generally requires the loss of heterozygosity (LOH) at one or more loci. Thus, the ability to determine whether a chemical is capable of causing LOH is an important part of cancer hazard identification. The mouse lymphoma assay detects a broad spectrum of geneti...

  4. Next generation microbiological risk assessment-Potential of omics data for hazard characterisation.

    PubMed

    Haddad, Nabila; Johnson, Nick; Kathariou, Sophia; Métris, Aline; Phister, Trevor; Pielaat, Annemarie; Tassou, Chrysoula; Wells-Bennik, Marjon H J; Zwietering, Marcel H

    2018-04-12

    According to the World Health Organization estimates in 2015, 600 million people fall ill every year from contaminated food and 420,000 die. Microbial risk assessment (MRA) was developed as a tool to reduce and prevent risks presented by pathogens and/or their toxins. MRA is organized in four steps to analyse information and assist in both designing appropriate control options and implementation of regulatory decisions and programs. Among the four steps, hazard characterisation is performed to establish the probability and severity of a disease outcome, which is determined as function of the dose of toxin and/or pathogen ingested. This dose-response relationship is subject to both variability and uncertainty. The purpose of this review/opinion article is to discuss how Next Generation Omics can impact hazard characterisation and, more precisely, how it can improve our understanding of variability and limit the uncertainty in the dose-response relation. The expansion of omics tools (e.g. genomics, transcriptomics, proteomics and metabolomics) allows for a better understanding of pathogenicity mechanisms and virulence levels of bacterial strains. Detection and identification of virulence genes, comparative genomics, analyses of mRNA and protein levels and the development of biomarkers can help in building a mechanistic dose-response model to predict disease severity. In this respect, systems biology can help to identify critical system characteristics that confer virulence and explain variability between strains. Despite challenges in the integration of omics into risk assessment, some omics methods have already been used by regulatory agencies for hazard identification. Standardized methods, reproducibility and datasets obtained from realistic conditions remain a challenge, and are needed to improve accuracy of hazard characterisation. When these improvements are realized, they will allow the health authorities and government policy makers to prioritize hazards more accurately and thus refine surveillance programs with the collaboration of all stakeholders of the food chain. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

  5. EPCRA Tier II Emergency and Hazardous Chemical Inventory Form

    EPA Pesticide Factsheets

    Required for Emergency and Hazardous Chemical Inventory reporting. Must provide facility identification, chemical description, indication of physical and health hazards, inventory information, and storage details.

  6. Detection, identification, and quantification techniques for spills of hazardous chemicals

    NASA Technical Reports Server (NTRS)

    Washburn, J. F.; Sandness, G. A.

    1977-01-01

    The first 400 chemicals listed in the Coast Guard's Chemical Hazards Response Information System were evaluated with respect to their detectability, identifiability, and quantifiability by 12 generalized remote and in situ sensing techniques. Identification was also attempted for some key areas in water pollution sensing technology.

  7. 44 CFR 65.16 - Standard Flood Hazard Determination Form and Instructions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Standard Flood Hazard... MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY INSURANCE AND HAZARD MITIGATION National Flood Insurance Program IDENTIFICATION AND MAPPING OF SPECIAL HAZARD AREAS § 65.16 Standard Flood Hazard Determination...

  8. 40 CFR 261.10 - Criteria for identifying the characteristics of hazardous waste.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... characteristics of hazardous waste. 261.10 Section 261.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Criteria for Identifying the Characteristics of Hazardous Waste and for Listing Hazardous Waste § 261.10 Criteria for...

  9. 40 CFR 261.10 - Criteria for identifying the characteristics of hazardous waste.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... characteristics of hazardous waste. 261.10 Section 261.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Criteria for Identifying the Characteristics of Hazardous Waste and for Listing Hazardous Waste § 261.10 Criteria for...

  10. 40 CFR 261.10 - Criteria for identifying the characteristics of hazardous waste.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... characteristics of hazardous waste. 261.10 Section 261.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Criteria for Identifying the Characteristics of Hazardous Waste and for Listing Hazardous Waste § 261.10 Criteria for...

  11. 40 CFR 261.10 - Criteria for identifying the characteristics of hazardous waste.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... characteristics of hazardous waste. 261.10 Section 261.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Criteria for Identifying the Characteristics of Hazardous Waste and for Listing Hazardous Waste § 261.10 Criteria for...

  12. 40 CFR 261.10 - Criteria for identifying the characteristics of hazardous waste.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... characteristics of hazardous waste. 261.10 Section 261.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Criteria for Identifying the Characteristics of Hazardous Waste and for Listing Hazardous Waste § 261.10 Criteria for...

  13. Controlling organic chemical hazards in food manufacturing: a hazard analysis critical control points (HACCP) approach.

    PubMed

    Ropkins, K; Beck, A J

    2002-08-01

    Hazard analysis by critical control points (HACCP) is a systematic approach to the identification, assessment and control of hazards. Effective HACCP requires the consideration of all hazards, i.e., chemical, microbiological and physical. However, to-date most 'in-place' HACCP procedures have tended to focus on the control of microbiological and physical food hazards. In general, the chemical component of HACCP procedures is either ignored or limited to applied chemicals, e.g., food additives and pesticides. In this paper we discuss the application of HACCP to a broader range of chemical hazards, using organic chemical contaminants as examples, and the problems that are likely to arise in the food manufacturing sector. Chemical HACCP procedures are likely to result in many of the advantages previously identified for microbiological HACCP procedures: more effective, efficient and economical than conventional end-point-testing methods. However, the high costs of analytical monitoring of chemical contaminants and a limited understanding of formulation and process optimisation as means of controlling chemical contamination of foods are likely to prevent chemical HACCP becoming as effective as microbiological HACCP.

  14. Application of the remote-sensing communication model to a time-sensitive wildfire remote-sensing system

    Treesearch

    Christopher D. Lippitt; Douglas A. Stow; Philip J. Riggan

    2016-01-01

    Remote sensing for hazard response requires a priori identification of sensor, transmission, processing, and distribution methods to permit the extraction of relevant information in timescales sufficient to allow managers to make a given time-sensitive decision. This study applies and demonstrates the utility of the Remote Sensing Communication...

  15. Logistic Regression in the Identification of Hazards in Construction

    NASA Astrophysics Data System (ADS)

    Drozd, Wojciech

    2017-10-01

    The construction site and its elements create circumstances that are conducive to the formation of risks to safety during the execution of works. Analysis indicates the critical importance of these factors in the set of characteristics that describe the causes of accidents in the construction industry. This article attempts to analyse the characteristics related to the construction site, in order to indicate their importance in defining the circumstances of accidents at work. The study includes sites inspected in 2014 - 2016 by the employees of the District Labour Inspectorate in Krakow (Poland). The analysed set of detailed (disaggregated) data includes both quantitative and qualitative characteristics. The substantive task focused on classification modelling in the identification of hazards in construction and identifying those of the analysed characteristics that are important in an accident. In terms of methodology, resource data analysis using statistical classifiers, in the form of logistic regression, was the method used.

  16. Hazard Screening Methods for Nanomaterials: A Comparative Study

    PubMed Central

    Murphy, Finbarr; Mullins, Martin; Furxhi, Irini; Costa, Anna L.; Simeone, Felice C.

    2018-01-01

    Hazard identification is the key step in risk assessment and management of manufactured nanomaterials (NM). However, the rapid commercialisation of nano-enabled products continues to out-pace the development of a prudent risk management mechanism that is widely accepted by the scientific community and enforced by regulators. However, a growing body of academic literature is developing promising quantitative methods. Two approaches have gained significant currency. Bayesian networks (BN) are a probabilistic, machine learning approach while the weight of evidence (WoE) statistical framework is based on expert elicitation. This comparative study investigates the efficacy of quantitative WoE and Bayesian methodologies in ranking the potential hazard of metal and metal-oxide NMs—TiO2, Ag, and ZnO. This research finds that hazard ranking is consistent for both risk assessment approaches. The BN and WoE models both utilize physico-chemical, toxicological, and study type data to infer the hazard potential. The BN exhibits more stability when the models are perturbed with new data. The BN has the significant advantage of self-learning with new data; however, this assumes all input data is equally valid. This research finds that a combination of WoE that would rank input data along with the BN is the optimal hazard assessment framework. PMID:29495342

  17. New capability for hazardous materials ID within sealed containers using a portable spatially offset Raman spectroscopy (SORS) device

    NASA Astrophysics Data System (ADS)

    Stokes, Robert J.; Bailey, Mike; Bonthron, Stuart; Stone, Thomas; Maskall, Guy; Presly, Oliver; Roy, Eric; Tombling, Craig; Loeffen, Paul W.

    2016-10-01

    Raman spectroscopy allows the acquisition of molecularly specific signatures of pure compounds and mixtures making it a popular method for material identification applications. In hazardous materials, security and counter terrorism applications, conventional handheld Raman systems are typically limited to operation by line-of-sight or through relatively transparent plastic bags / clear glass vials. If materials are concealed behind thicker, coloured or opaque barriers it can be necessary to open and take a sample. Spatially Offset Raman Spectroscopy (SORS)[1] is a novel variant of Raman spectroscopy whereby multiple measurements at differing positions are used to separate the spectrum arising from the sub layers of a sample from the spectrum at the surface. For the first time, a handheld system based on SORS has been developed and applied to hazardous materials identification. The system - "Resolve" - enables new capabilities in the rapid identification of materials concealed by a wide variety of non-metallic sealed containers such as; coloured and opaque plastics, paper, card, sacks, fabric and glass. The range of potential target materials includes toxic industrial chemicals, explosives, narcotics, chemical warfare agents and biological materials. Resolve has the potential to improve the safety, efficiency and critical decision making in incident management, search operations, policing and ports and border operations. The operator is able to obtain a positive identification of a potentially hazardous material without opening or disturbing the container - to gain access to take a sample - thus improving safety. The technique is fast and simple thus suit and breathing gear time is used more efficiently. SORS also allows Raman to be deployed at an earlier stage in an event before more intrusive techniques are used. Evidential information is preserved and the chain of custody protected. Examples of detection capability for a number of materials and barrier types are presented below.

  18. 40 CFR 241.3 - Standards and procedures for identification of non-hazardous secondary materials that are solid...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... combustion units. 241.3 Section 241.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOLID WASTES USED AS FUELS OR INGREDIENTS IN COMBUSTION UNITS Identification of Non-Hazardous Secondary Materials That Are Solid Wastes When Used as Fuels or Ingredients in Combustion Units...

  19. 40 CFR 241.3 - Standards and procedures for identification of non-hazardous secondary materials that are solid...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... combustion units. 241.3 Section 241.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOLID WASTES USED AS FUELS OR INGREDIENTS IN COMBUSTION UNITS Identification of Non-Hazardous Secondary Materials That Are Solid Wastes When Used as Fuels or Ingredients in Combustion Units...

  20. 40 CFR 241.3 - Standards and procedures for identification of non-hazardous secondary materials that are solid...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... combustion units. 241.3 Section 241.3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES SOLID WASTES USED AS FUELS OR INGREDIENTS IN COMBUSTION UNITS Identification of Non-Hazardous Secondary Materials That Are Solid Wastes When Used as Fuels or Ingredients in Combustion Units...

  1. Identification, assessment, and control of hazards in water supply: experiences from Water Safety Plan implementations in Germany.

    PubMed

    Mälzer, H-J; Staben, N; Hein, A; Merkel, W

    2010-01-01

    According to the recommendations of the World Health Organization (WHO) for Water Safety Plans (WSP), a Technical Risk Management was developed, which considers standard demands in drinking water treatment in Germany. It was already implemented at several drinking water treatment plants of different size and treatment processes in Germany. Hazards affecting water quality, continuity, and the reliability of supply from catchment to treatment and distribution could be identified by a systematic approach, and suitable control measures were defined. Experiences are presented by detailed examples covering methods, practical consequences, and further outcomes. The method and the benefits for the water suppliers are discussed and an outlook on the future role of WSPs in German water supply is given.

  2. Application of a hazard and operability study method to hazard evaluation of a chemical unit of the power station.

    PubMed

    Habibi, E; Zare, M; Barkhordari, A; Mirmohammadi, Sj; Halvani, Ghh

    2008-12-28

    The aim of this study was to identify the hazards, evaluate their risk factors and determine the measure for promotion of the process and reduction of accidents in the chemical unit of the power station. In this case and qualitative study, HAZOP technique was used to recognize the hazards and problems of operations on the chemical section at power station. Totally, 126 deviations were documented with various causes and consequences. Ranking and evaluation of identified risks indicate that the majority of deviations were categorized as "acceptable" and less than half of that were "unacceptable". The highest calculated risk level (1B) related to both the interruption of acid entry to the discharge pumps and an increased density of the acid. About 27% of the deviations had the lowest risk level (4B). The identification of hazards by HAZOP indicates that it could, systemically, assess and criticize the process of consumption or production of acid and alkali in the chemical unit of power plant.

  3. Essential Limitations of the Standard THz TDS Method for Substance Detection and Identification and a Way of Overcoming Them

    PubMed Central

    Trofimov, Vyacheslav A.; Varentsova, Svetlana A.

    2016-01-01

    Low efficiency of the standard THz TDS method of the detection and identification of substances based on a comparison of the spectrum for the signal under investigation with a standard signal spectrum is demonstrated using the physical experiments conducted under real conditions with a thick paper bag as well as with Si-based semiconductors under laboratory conditions. In fact, standard THz spectroscopy leads to false detection of hazardous substances in neutral samples, which do not contain them. This disadvantage of the THz TDS method can be overcome by using time-dependent THz pulse spectrum analysis. For a quality assessment of the standard substance spectral features presence in the signal under analysis, one may use time-dependent integral correlation criteria. PMID:27070617

  4. Essential Limitations of the Standard THz TDS Method for Substance Detection and Identification and a Way of Overcoming Them.

    PubMed

    Trofimov, Vyacheslav A; Varentsova, Svetlana A

    2016-04-08

    Low efficiency of the standard THz TDS method of the detection and identification of substances based on a comparison of the spectrum for the signal under investigation with a standard signal spectrum is demonstrated using the physical experiments conducted under real conditions with a thick paper bag as well as with Si-based semiconductors under laboratory conditions. In fact, standard THz spectroscopy leads to false detection of hazardous substances in neutral samples, which do not contain them. This disadvantage of the THz TDS method can be overcome by using time-dependent THz pulse spectrum analysis. For a quality assessment of the standard substance spectral features presence in the signal under analysis, one may use time-dependent integral correlation criteria.

  5. A SMALL FISH MULTI-ENDPOINT BIOASSAY FOR ASSESSING THE EFFECTS OF WATER CONTAMINANTS PRESENT IN LOW CONCENTRATIONS: MEDAKA AND DICHLOROACETIC ACID

    EPA Science Inventory

    In regulating the safety of water under SDWA and the CWA, the EPA makes decisions on what chemical contaminants to regulate and at what levels. To make these decisions the EPA needs hazard identification and dose-response information. Current methods that rely on rodent models fo...

  6. Chemical hazards database and detection system for Microgravity and Materials Processing Facility (MMPF)

    NASA Technical Reports Server (NTRS)

    Steele, Jimmy; Smith, Robert E.

    1991-01-01

    The ability to identify contaminants associated with experiments and facilities is directly related to the safety of the Space Station. A means of identifying these contaminants has been developed through this contracting effort. The delivered system provides a listing of the materials and/or chemicals associated with each facility, information as to the contaminant's physical state, a list of the quantity and/or volume of each suspected contaminant, a database of the toxicological hazards associated with each contaminant, a recommended means of rapid identification of the contaminants under operational conditions, a method of identifying possible failure modes and effects analysis associated with each facility, and a fault tree-type analysis that will provide a means of identifying potential hazardous conditions related to future planned missions.

  7. Performance of tensor decomposition-based modal identification under nonstationary vibration

    NASA Astrophysics Data System (ADS)

    Friesen, P.; Sadhu, A.

    2017-03-01

    Health monitoring of civil engineering structures is of paramount importance when they are subjected to natural hazards or extreme climatic events like earthquake, strong wind gusts or man-made excitations. Most of the traditional modal identification methods are reliant on stationarity assumption of the vibration response and posed difficulty while analyzing nonstationary vibration (e.g. earthquake or human-induced vibration). Recently tensor decomposition based methods are emerged as powerful and yet generic blind (i.e. without requiring a knowledge of input characteristics) signal decomposition tool for structural modal identification. In this paper, a tensor decomposition based system identification method is further explored to estimate modal parameters using nonstationary vibration generated due to either earthquake or pedestrian induced excitation in a structure. The effects of lag parameters and sensor densities on tensor decomposition are studied with respect to the extent of nonstationarity of the responses characterized by the stationary duration and peak ground acceleration of the earthquake. A suite of more than 1400 earthquakes is used to investigate the performance of the proposed method under a wide variety of ground motions utilizing both complete and partial measurements of a high-rise building model. Apart from the earthquake, human-induced nonstationary vibration of a real-life pedestrian bridge is also used to verify the accuracy of the proposed method.

  8. 40 CFR 261.7 - Residues of hazardous waste in empty containers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Residues of hazardous waste in empty containers. 261.7 Section 261.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE General § 261.7 Residues of hazardous...

  9. Non-therapist identification of falling hazards in older adult homes using digital photography.

    PubMed

    Ritchey, Katherine C; Meyer, Deborah; Ice, Gillian H

    2015-01-01

    Evaluation and removal of home hazards is an invaluable method for preventing in-home falls and preserving independent living. Current processes for conducting home hazard assessments are impractical from a whole population standpoint given the substantial resources required for implementation. Digital photography offers an opportunity to remotely evaluate an environment for falling hazards. However, reliability of this method has only been tested under the direction of skilled therapists. Ten community dwelling adults over the age of 65 were recruited from local primary care practices between July, 2009 and February, 2010. In-home (IH) assessments were completed immediately after a photographer, blinded to the assessment form, took digital photographs (DP) of the participant home. A different non-therapist assessor then reviewed the photographs and completed a second assessment of the home. Kappa statistic was used to analyze the reliability between the two independent assessments. Home assessments completed by a non-therapist using digital photographs had a substantial agreement (Kappa = 0.61, p < 0.001) with in-home assessments completed by another non-therapist. Additionally, the DP assessments agreed with the IH assessments on the presence or absence of items 96.8% of the time. This study showed that non-therapists can reliably conduct home hazard evaluations using digital photographs.

  10. Improving identification of traumatic brain injury after nonmilitary bomb blasts.

    PubMed

    Rutland-Brown, Wesley; Langlois, Jean A; Bazarian, Jeffrey J; Warden, Deborah

    2008-01-01

    To improve identification of traumatic brain injury (TBI) in survivors of nonmilitary bomb blasts during the acute care phase. The Centers for Disease Control and Prevention convened a meeting of experts in TBI, emergency medicine, and disaster response to review the recent literature and make recommendations. Seven key recommendations were proposed: (1) increase TBI awareness among medical professionals; (2) encourage use of standard definitions and consistent terminology; (3) improve screening methods for TBI in the acute care setting; (4) clarify the distinction between TBI and acute stress disorder; (5) encourage routine screening of hospitalized trauma patients for TBI; (6) improve identification of nonhospitalized TBI patients; and (7) integrate the appropriate level of TBI identification into all-hazards mass casualty preparedness. By adopting these recommendations, the United States could be better prepared to identify and respond to TBI following future bombing events.

  11. 40 CFR 261.142 - Cost estimate.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Financial Requirements for Management of Excluded Hazardous Secondary... hazardous waste, and the potential cost of closing the facility as a treatment, storage, and disposal...

  12. 40 CFR 261.142 - Cost estimate.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Financial Requirements for Management of Excluded Hazardous Secondary... hazardous waste, and the potential cost of closing the facility as a treatment, storage, and disposal...

  13. 40 CFR 261.142 - Cost estimate.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Financial Requirements for Management of Excluded Hazardous Secondary... hazardous waste, and the potential cost of closing the facility as a treatment, storage, and disposal...

  14. Advanced Ultrasonic Measurement Methodology for Non-Invasive Interrogation and Identification of Fluids in Sealed Containers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tucker, Brian J.; Diaz, Aaron A.; Eckenrode, Brian A.

    2006-03-16

    The Hazardous Materials Response Unit (HMRU) and the Counterterrorism and Forensic Science Research Unit (CTFSRU), Laboratory Division, Federal Bureau of Investigation (FBI) have been mandated to develop and establish a wide range of unprecedented capabilities for providing scientific and technical forensic services to investigations involving hazardous chemical, biological, and radiological materials, including extremely dangerous chemical and biological warfare agents. Pacific Northwest National Laboratory (PNNL) has developed a portable, hand-held, hazardous materials acoustic inspection device (HAZAID) that provides noninvasive container interrogation and material identification capabilities using nondestructive ultrasonic velocity and attenuation measurements. Due to the wide variety of fluids as wellmore » as container sizes and materials, the need for high measurement sensitivity and advanced ultrasonic measurement techniques were identified. The HAZAID prototype was developed using a versatile electronics platform, advanced ultrasonic wave propagation methods, and advanced signal processing techniques. This paper primarily focuses on the ultrasonic measurement methods and signal processing techniques incorporated into the HAZAID prototype. High bandwidth ultrasonic transducers combined with the advanced pulse compression technique allowed researchers to 1) impart large amounts of energy, 2) obtain high signal-to-noise ratios, and 3) obtain accurate and consistent time-of-flight (TOF) measurements through a variety of highly attenuative containers and fluid media. Results of this feasibility study demonstrated that the HAZAID experimental measurement technique also provided information regarding container properties, which will be utilized in future container-independent measurements of hidden liquids.« less

  15. Remotely Sensed Hydrometeorological and Agrometeorological Drought Risk Identification for Sustainable Agriculture.

    NASA Astrophysics Data System (ADS)

    Dalezios, Nicolas R.; Blanta, Anna; Spyropoulos, Nicos

    2013-04-01

    Drought is considered as one of the major environmental hazards with significant impacts to agriculture, environment, economy and society. This paper addresses drought as a hazard within the risk management framework. Indeed, hazards may be defined as a potential threat to humans and their welfare and risk (or consequence) as the probability of a hazard occurring and creating loss. Besides, risk management consists of risk assessment and feedback of the adopted risk reduction measures. And risk assessment comprises three distinct steps, namely risk identification, risk estimation and risk evaluation. In order to ensure sustainability in agricultural production a better understanding of the natural disasters, in particular droughts, that impact agriculture is essential. Droughts may result in environmental degradation of an area, which is one of the factors contributing to the vulnerability of agriculture, because it directly magnifies the risk of natural disasters. This paper deals with drought risk identification, which involves hazard quantification, event monitoring including early warning systems and statistical inference. For drought quantification the Reconnaissance Drought Index (RDI) combined with Vegetation Health Index (VHI) is employed. RDI is a new index based on hydrometeorological parameters, and in particular precipitation and potential evapotranspiration, which has been recently modified to incorporate monthly satellite (NOAA/AVHAA) data for a period of 20 years (1981-2001). VHI is based on NDVI. The study area is Thessaly in central Greece, which is one of the major agricultural areas of the country occasionally facing droughts. Drought monitoring is conducted by monthly remotely sensed RID and VHI images and several drought features are extracted such as severity, duration, areal extent, onset and end time. Drought early warning is developed using empirical relationships of the above mentioned features. In particular, two second-order polynomials are fitted relating severity and areal extend (number of pixels), one for low and other for high severity drought. The two fitted curves offer a forecasting tool on a monthly basis from the beginning of each hydrological year with high severity droughts occurring from October, whereas low severity droughts start in April. The results of this drought risk identification effort are considered quite satisfactory offering a prognostic potential of drought. The adopted remote sensing data and methods have proven very effective in delineating spatial variability and features in drought quantification and monitoring.

  16. Radiophysical methods of diagnostics the Earth's ionosphere and the underlying earth's surface by remote sensing in the short-wave range of radio waves

    NASA Astrophysics Data System (ADS)

    Belov, S. Yu.; Belova, I. N.

    2017-11-01

    Monitoring of the earth's surface by remote sensing in the short-wave band can provide quick identification of some characteristics of natural systems. This band range allows one to diagnose subsurface aspects of the earth, as the scattering parameter is affected by irregularities in the dielectric permittivity of subsurface structures. This method based on the organization of the monitoring probe may detect changes in these environments, for example, to assess seismic hazard, hazardous natural phenomena such as earthquakes, as well as some man-made hazards and etc. The problem of measuring and accounting for the scattering power of the earth's surface in the short-range of radio waves is important for a number of purposes, such as diagnosing properties of the medium, which is of interest for geological, environmental studies. In this paper, we propose a new method for estimating the parameters of incoherent signal/noise ratio. The paper presents the results of comparison of the measurement method from the point of view of their admissible relative analytical errors. The new method is suggested. Analysis of analytical error of estimation of this parameter allowed to recommend new method instead of standard method. A comparative analysis and shows that the analytical (relative) accuracy of the determination of this parameter new method on the order exceeds the widely-used standard method.

  17. 75 FR 73972 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Removal of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-30

    ... adverse comment by October 25, 2010, the direct final rule would not take effect and we would publish a.... Lists of Subjects in 40 CFR Part 261 Environmental Protection, Hazardous waste, Recycling, Reporting and...

  18. Exploring the effects of driving experience on hazard awareness and risk perception via real-time hazard identification, hazard classification, and rating tasks.

    PubMed

    Borowsky, Avinoam; Oron-Gilad, Tal

    2013-10-01

    This study investigated the effects of driving experience on hazard awareness and risk perception skills. These topics have previously been investigated separately, yet a novel approach is suggested where hazard awareness and risk perception are examined concurrently. Young, newly qualified drivers, experienced drivers, and a group of commercial drivers, namely, taxi drivers performed three consecutive tasks: (1) observed 10 short movies of real-world driving situations and were asked to press a button each time they identified a hazardous situation; (2) observed one of three possible sub-sets of 8 movies (out of the 10 they have seen earlier) for the second time, and were asked to categorize them into an arbitrary number of clusters according to the similarity in their hazardous situation; and (3) observed the same sub-set for a third time and following each movie were asked to rate its level of hazardousness. The first task is considered a real-time identification task while the other two are performed using hindsight. During it participants' eye movements were recorded. Results showed that taxi drivers were more sensitive to hidden hazards than the other driver groups and that young-novices were the least sensitive. Young-novice drivers also relied heavily on materialized hazards in their categorization structure. In addition, it emerged that risk perception was derived from two major components: the likelihood of a crash and the severity of its outcome. Yet, the outcome was rarely considered under time pressure (i.e., in real-time hazard identification tasks). Using hindsight, when drivers were provided with the opportunity to rate the movies' hazardousness more freely (rating task) they considered both components. Otherwise, in the categorization task, they usually chose the severity of the crash outcome as their dominant criterion. Theoretical and practical implications are discussed. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Institutionalizing fire safety in making land use and development decisions

    Treesearch

    Marie-Annette Johnson; Marc Mullenix

    1995-01-01

    Because of three major wildland fires in the past 5 years along the Front Range of the Boulder County area in Colorado, current and potential residents should be told of steps that can reduce the risks of these fire hazards. The Wildfire Hazard Identification and Mitigation System (WHIMS) is used by the county and city to assist in the identification and mitigation of...

  20. Analysis and improved design considerations for airborne pulse Doppler radar signal processing in the detection of hazardous windshear

    NASA Technical Reports Server (NTRS)

    Lee, Jonggil

    1990-01-01

    High resolution windspeed profile measurements are needed to provide reliable detection of hazardous low altitude windshear with an airborne pulse Doppler radar. The system phase noise in a Doppler weather radar may degrade the spectrum moment estimation quality and the clutter cancellation capability which are important in windshear detection. Also the bias due to weather return Doppler spectrum skewness may cause large errors in pulse pair spectral parameter estimates. These effects are analyzed for the improvement of an airborne Doppler weather radar signal processing design. A method is presented for the direct measurement of windspeed gradient using low pulse repetition frequency (PRF) radar. This spatial gradient is essential in obtaining the windshear hazard index. As an alternative, the modified Prony method is suggested as a spectrum mode estimator for both the clutter and weather signal. Estimation of Doppler spectrum modes may provide the desired windshear hazard information without the need of any preliminary processing requirement such as clutter filtering. The results obtained by processing a NASA simulation model output support consideration of mode identification as one component of a windshear detection algorithm.

  1. Identification and delineation of areas flood hazard using high accuracy of DEM data

    NASA Astrophysics Data System (ADS)

    Riadi, B.; Barus, B.; Widiatmaka; Yanuar, M. J. P.; Pramudya, B.

    2018-05-01

    Flood incidents that often occur in Karawang regency need to be mitigated. These expectations exist on technologies that can predict, anticipate and reduce disaster risks. Flood modeling techniques using Digital Elevation Model (DEM) data can be applied in mitigation activities. High accuracy DEM data used in modeling, will result in better flooding flood models. The result of high accuracy DEM data processing will yield information about surface morphology which can be used to identify indication of flood hazard area. The purpose of this study was to identify and describe flood hazard areas by identifying wetland areas using DEM data and Landsat-8 images. TerraSAR-X high-resolution data is used to detect wetlands from landscapes, while land cover is identified by Landsat image data. The Topography Wetness Index (TWI) method is used to detect and identify wetland areas with basic DEM data, while for land cover analysis using Tasseled Cap Transformation (TCT) method. The result of TWI modeling yields information about potential land of flood. Overlay TWI map with land cover map that produces information that in Karawang regency the most vulnerable areas occur flooding in rice fields. The spatial accuracy of the flood hazard area in this study was 87%.

  2. Automated Purgatoid Identification: Final Report

    NASA Technical Reports Server (NTRS)

    Wood, Steven

    2011-01-01

    Driving on Mars is hazardous: technical problems and unforeseen natural hazards can end a mission quickly at the worst, or result in long delays at best. This project is focused on helping to mitigate hazards posed to rovers by purgatoids: small (less than 1 m high, less than 10 m wide), ripple-like eolian bedforms commonly found scattered across the Meridiani Planum region of Mars. Due to the poorly consolidated nature of purgatoids and multiple past episodes of rovers getting stuck in them, identification and avoidance of these eolian bedforms is an important feature of rover path planning (NASA, 2011).

  3. Master Logic Diagram: method for hazard and initiating event identification in process plants.

    PubMed

    Papazoglou, I A; Aneziris, O N

    2003-02-28

    Master Logic Diagram (MLD), a method for identifying events initiating accidents in chemical installations, is presented. MLD is a logic diagram that resembles a fault tree but without the formal mathematical properties of the latter. MLD starts with a Top Event "Loss of Containment" and decomposes it into simpler contributing events. A generic MLD has been developed which may be applied to all chemical installations storing toxic and/or flammable substances. The method is exemplified through its application to an ammonia storage facility.

  4. Hazardous Waste Management System: Identification and Listing of Hazardous Waste - Burning of Hazardous Waste in Boilers and Industrial Furnaces - Federal Register Notice, September 5, 1991

    EPA Pesticide Factsheets

    EPA is announcing an administrative stay of the permitting standards for boilers and industrial furnaces adopted pursuant to the Resource Conservation and Recovery Act (56 FR 7206, Feb. 21, 1991) as they apply to coke ovens burning certain hazardous wastes

  5. Machine Learning Methods for Production Cases Analysis

    NASA Astrophysics Data System (ADS)

    Mokrova, Nataliya V.; Mokrov, Alexander M.; Safonova, Alexandra V.; Vishnyakov, Igor V.

    2018-03-01

    Approach to analysis of events occurring during the production process were proposed. Described machine learning system is able to solve classification tasks related to production control and hazard identification at an early stage. Descriptors of the internal production network data were used for training and testing of applied models. k-Nearest Neighbors and Random forest methods were used to illustrate and analyze proposed solution. The quality of the developed classifiers was estimated using standard statistical metrics, such as precision, recall and accuracy.

  6. 40 CFR 262.12 - EPA identification numbers.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 26 2014-07-01 2014-07-01 false EPA identification numbers. 262.12... (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE General § 262.12 EPA identification numbers... waste without having received an EPA identification number from the Administrator. (b) A generator who...

  7. 40 CFR 262.12 - EPA identification numbers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false EPA identification numbers. 262.12... (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE General § 262.12 EPA identification numbers... waste without having received an EPA identification number from the Administrator. (b) A generator who...

  8. 40 CFR 262.12 - EPA identification numbers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 27 2012-07-01 2012-07-01 false EPA identification numbers. 262.12... (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE General § 262.12 EPA identification numbers... waste without having received an EPA identification number from the Administrator. (b) A generator who...

  9. 40 CFR 262.12 - EPA identification numbers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 27 2013-07-01 2013-07-01 false EPA identification numbers. 262.12... (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE General § 262.12 EPA identification numbers... waste without having received an EPA identification number from the Administrator. (b) A generator who...

  10. 40 CFR 262.12 - EPA identification numbers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 26 2011-07-01 2011-07-01 false EPA identification numbers. 262.12... (CONTINUED) STANDARDS APPLICABLE TO GENERATORS OF HAZARDOUS WASTE General § 262.12 EPA identification numbers... waste without having received an EPA identification number from the Administrator. (b) A generator who...

  11. Balancing research and funding using value of information and portfolio tools for nanomaterial risk classification

    NASA Astrophysics Data System (ADS)

    Bates, Matthew E.; Keisler, Jeffrey M.; Zussblatt, Niels P.; Plourde, Kenton J.; Wender, Ben A.; Linkov, Igor

    2016-02-01

    Risk research for nanomaterials is currently prioritized by means of expert workshops and other deliberative processes. However, analytical techniques that quantify and compare alternative research investments are increasingly recommended. Here, we apply value of information and portfolio decision analysis—methods commonly applied in financial and operations management—to prioritize risk research for multiwalled carbon nanotubes and nanoparticulate silver and titanium dioxide. We modify the widely accepted CB Nanotool hazard evaluation framework, which combines nano- and bulk-material properties into a hazard score, to operate probabilistically with uncertain inputs. Literature is reviewed to develop uncertain estimates for each input parameter, and a Monte Carlo simulation is applied to assess how different research strategies can improve hazard classification. The relative cost of each research experiment is elicited from experts, which enables identification of efficient research portfolios—combinations of experiments that lead to the greatest improvement in hazard classification at the lowest cost. Nanoparticle shape, diameter, solubility and surface reactivity were most frequently identified within efficient portfolios in our results.

  12. Balancing research and funding using value of information and portfolio tools for nanomaterial risk classification.

    PubMed

    Bates, Matthew E; Keisler, Jeffrey M; Zussblatt, Niels P; Plourde, Kenton J; Wender, Ben A; Linkov, Igor

    2016-02-01

    Risk research for nanomaterials is currently prioritized by means of expert workshops and other deliberative processes. However, analytical techniques that quantify and compare alternative research investments are increasingly recommended. Here, we apply value of information and portfolio decision analysis-methods commonly applied in financial and operations management-to prioritize risk research for multiwalled carbon nanotubes and nanoparticulate silver and titanium dioxide. We modify the widely accepted CB Nanotool hazard evaluation framework, which combines nano- and bulk-material properties into a hazard score, to operate probabilistically with uncertain inputs. Literature is reviewed to develop uncertain estimates for each input parameter, and a Monte Carlo simulation is applied to assess how different research strategies can improve hazard classification. The relative cost of each research experiment is elicited from experts, which enables identification of efficient research portfolios-combinations of experiments that lead to the greatest improvement in hazard classification at the lowest cost. Nanoparticle shape, diameter, solubility and surface reactivity were most frequently identified within efficient portfolios in our results.

  13. Identification and apportionment of hazardous elements in the sediments in the Yangtze River estuary.

    PubMed

    Wang, Jiawei; Liu, Ruimin; Wang, Haotian; Yu, Wenwen; Xu, Fei; Shen, Zhenyao

    2015-12-01

    In this study, positive matrix factorization (PMF) and principal components analysis (PCA) were combined to identify and apportion pollution-based sources of hazardous elements in the surface sediments in the Yangtze River estuary (YRE). Source identification analysis indicated that PC1, including Al, Fe, Mn, Cr, Ni, As, Cu, and Zn, can be defined as a sewage component; PC2, including Pb and Sb, can be considered as an atmospheric deposition component; and PC3, containing Cd and Hg, can be considered as an agricultural nonpoint component. To better identify the sources and quantitatively apportion the concentrations to their sources, eight sources were identified with PMF: agricultural/industrial sewage mixed (18.6 %), mining wastewater (15.9 %), agricultural fertilizer (14.5 %), atmospheric deposition (12.8 %), agricultural nonpoint (10.6 %), industrial wastewater (9.8 %), marine activity (9.0 %), and nickel plating industry (8.8 %). Overall, the hazardous element content seems to be more connected to anthropogenic activity instead of natural sources. The PCA results laid the foundation for the PMF analysis by providing a general classification of sources. PMF resolves more factors with a higher explained variance than PCA; PMF provided both the internal analysis and the quantitative analysis. The combination of the two methods can provide more reasonable and reliable results.

  14. Preharvest food safety.

    PubMed

    Childers, A B; Walsh, B

    1996-07-23

    Preharvest food safety is essential for the protection of our food supply. The production and transport of livestock and poultry play an integral part in the safety of these food products. The goals of this safety assurance include freedom from pathogenic microorganisms, disease, and parasites, and from potentially harmful residues and physical hazards. Its functions should be based on hazard analysis and critical control points from producer to slaughter plant with emphasis on prevention of identifiable hazards rather than on removal of contaminated products. The production goal is to minimize infection and insure freedom from potentially harmful residues and physical hazards. The marketing goal is control of exposure to pathogens and stress. Both groups should have functional hazard analysis and critical control points management programs which include personnel training and certification of producers. These programs must cover production procedures, chemical usage, feeding, treatment practices, drug usage, assembly and transportation, and animal identification. Plans must use risk assessment principles, and the procedures must be defined. Other elements would include preslaughter certification, environmental protection, control of chemical hazards, live-animal drug-testing procedures, and identification of physical hazards.

  15. Identification of potentially emerging food safety issues by analysis of reports published by the European Community's Rapid Alert System for Food and Feed (RASFF) during a four-year period.

    PubMed

    Kleter, G A; Prandini, A; Filippi, L; Marvin, H J P

    2009-05-01

    The SAFE FOODS project undertakes to design a new approach towards the early identification of emerging food safety hazards. This study explored the utility of notifications filed through RASFF, the European Commission's Rapid Alert System for Food and Feed, to identify emerging trends in food safety issues. RASFF information and alert notifications published in the four-year period of July 2003-June 2007 were assigned to categories of products and hazards. For chronological trend analysis, a basic time unit of three months was chosen. Data within each hazard category were analyzed for chronological trends, relationships between product and hazard categories, regions of origin, and countries filing the notifications. Conspicuous trends that were observed included a rise in the incidence of food contact substances, particularly 2-isopropyl-thioxanthone, as well as of chemical substances migrating from utensils and fraud-related issues. Temporary increases were noted in the incidences of the unauthorized dye Para Red, genetically modified organisms, the pesticide isophenfos-methyl, and herring worm, Anisakis simplex. National and European authorities themselves have signaled these conspicuous trends and taken measures. It is recommended to add complementary data to RASFF data, including safety assessments, risk management measures, background data on hazards and surveillance patterns, for a holistic approach towards early identification of emerging hazards.

  16. Hazardous Waste Management Systems: Identification and Listing of Hazardous Waste - Federal Register Notice, May 1, 1991

    EPA Pesticide Factsheets

    The EPA is announcing an administrative stay of a portion of the hazardous waste listing K069 so that the listing does not apply to slurries generated from air pollution control devices that are intended to capture acid gases.

  17. Hazard Identification and Risk Assessment of Health and Safety Approach JSA (Job Safety Analysis) in Plantation Company

    NASA Astrophysics Data System (ADS)

    Sugarindra, Muchamad; Ragil Suryoputro, Muhammad; Tiya Novitasari, Adi

    2017-06-01

    Plantation company needed to identify hazard and perform risk assessment as an Identification of Hazard and Risk Assessment Crime and Safety which was approached by using JSA (Job Safety Analysis). The identification was aimed to identify the potential hazards that might be the risk of workplace accidents so that preventive action could be taken to minimize the accidents. The data was collected by direct observation to the workers concerned and the results were recorded on a Job Safety Analysis form. The data were as forklift operator, macerator worker, worker’s creeper, shredder worker, workers’ workshop, mechanical line worker, trolley cleaning workers and workers’ crepe decline. The result showed that shredder worker value was 30 and had the working level with extreme risk with the risk value range was above 20. So to minimize the accidents could provide Personal Protective Equipment (PPE) which were appropriate, information about health and safety, the company should have watched the activities of workers, and rewards for the workers who obey the rules that applied in the plantation.

  18. Applied Prevalence Ratio estimation with different Regression models: An example from a cross-national study on substance use research.

    PubMed

    Espelt, Albert; Marí-Dell'Olmo, Marc; Penelo, Eva; Bosque-Prous, Marina

    2016-06-14

    To examine the differences between Prevalence Ratio (PR) and Odds Ratio (OR) in a cross-sectional study and to provide tools to calculate PR using two statistical packages widely used in substance use research (STATA and R). We used cross-sectional data from 41,263 participants of 16 European countries participating in the Survey on Health, Ageing and Retirement in Europe (SHARE). The dependent variable, hazardous drinking, was calculated using the Alcohol Use Disorders Identification Test - Consumption (AUDIT-C). The main independent variable was gender. Other variables used were: age, educational level and country of residence. PR of hazardous drinking in men with relation to women was estimated using Mantel-Haenszel method, log-binomial regression models and poisson regression models with robust variance. These estimations were compared to the OR calculated using logistic regression models. Prevalence of hazardous drinkers varied among countries. Generally, men have higher prevalence of hazardous drinking than women [PR=1.43 (1.38-1.47)]. Estimated PR was identical independently of the method and the statistical package used. However, OR overestimated PR, depending on the prevalence of hazardous drinking in the country. In cross-sectional studies, where comparisons between countries with differences in the prevalence of the disease or condition are made, it is advisable to use PR instead of OR.

  19. Use of fake identification to purchase alcohol amongst 15-16 year olds: a cross-sectional survey examining alcohol access, consumption and harm.

    PubMed

    Morleo, Michela; Cook, Penny A; Bellis, Mark A; Smallthwaite, Linda

    2010-06-22

    Despite legislation and enforcement activities to prevent underage access to alcohol, underage individuals continue to be able to access alcohol and to do so at levels which put them at significant risk of alcohol-related harm. An opportunistic survey of 15-16 year olds (n = 9,833) across North West England was used to examine alcohol consumption, methods of access and related harms experienced (such as regretted sex). Associations between these were analysed using chi square and logistic regression techniques. Over a quarter (28.3%) of 15-16 year old participants who drank reported having bought their own alcohol. One seventh (14.9%) of these owned at least one form of fake identification for which by far the most common purchase method was online. Logistic regression analyses showed that those who owned fake identification were significantly more likely to be male (AOR = 2.0; 95% CI = 1.7-2.5; P < 0.001) and to receive a higher personal weekly income (comparing those who received > pound30 with those who received < or = pound10: AOR = 3.7; 95% CI = 2.9-4.9; P < 0.001). After taking into account differences in demographic characteristics and personal weekly income, ownership of fake identification was significantly associated with binge drinking (AOR = 3.5, 95% CI = 2.8-4.3; P < 0.001), frequent drinking (AOR = 3.0, 95% CI = 2.5-3.7; P < 0.001) and public drinking (AOR = 3.3, 95% CI = 2.5-4.1; P < 0.001) compared with those who did not own fake identification. Further, those who reported owning fake identification were significantly more likely to report experiencing a variety of alcohol-related harms such as regretted sex after drinking (chi square, all P < 0.001). Young people (aged 15-16 years) who have access to fake identification are at a particularly high risk of reporting hazardous alcohol consumption patterns and related harm. Owning fake identification should be considered a risk factor for involvement in risky drinking behaviours. Information on these hazards should be made available to schools and professionals in health, social and judicial services, along with advice on how to best to work with those involved.

  20. Identifying Populace Susceptible to Flooding Using ArcGIS and Remote Sensing Datasets

    NASA Astrophysics Data System (ADS)

    Fernandez, Sim Joseph; Milano, Alan

    2016-07-01

    Remote sensing technologies are growing vastly as with its various applications. The Department of Science and Technology (DOST), Republic of the Philippines, has made projects exploiting LiDAR datasets from remote sensing technologies. The Phil-LiDAR 1 project of DOST is a flood hazard mapping project. Among the project's objectives is the identification of building features which can be associated to the flood-exposed population. The extraction of building features from the LiDAR dataset is arduous as it requires manual identification of building features on an elevation map. The mapping of building footprints is made meticulous in order to compensate the accuracy between building floor area and building height both of which are crucial in flood decision making. A building identification method was developed to generate a LiDAR derivative which will serve as a guide in mapping building footprints. The method utilizes several tools of a Geographic Information System (GIS) software called ArcGIS which can operate on physical attributes of buildings such as roofing curvature, slope and blueprint area in order to obtain the LiDAR derivative from LiDAR dataset. The method also uses an intermediary process called building removal process wherein buildings and other features lying below the defined minimum building height - 2 meters in the case of Phil-LiDAR 1 project - are removed. The building identification method was developed in the hope to hasten the identification of building features especially when orthophotographs and/or satellite imageries are not made available.

  1. 75 FR 12989 - Hazardous Waste Technical Corrections and Clarifications Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-18

    ... regulations that relate to hazardous waste identification, manifesting, the hazardous waste generator..., NW., Washington, DC 20460. Attention Docket ID No. EPA-HQ-RCRA-2008-0678. Please include a total of 2 copies. Hand Delivery: EPA West Building, Room 3334, 1301 Constitution Ave., NW., Washington, DC. Such...

  2. Hazardous Waste Management System - Definition of Hazardous Waste - Mixture and Derived- From Rules - Federal Register Notice, October 30, 1992

    EPA Pesticide Factsheets

    This action responds to public comment on two proposals (57 FR 7636, March 3, 1992, and 57 FR 21450, May 20, 1992) to modify EPA's hazardous waste identification rules under the Resource Conservation and Recovery Act (RCRA).

  3. 76 FR 59960 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Withdrawal of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-28

    ... Landfill (Gulf West) located in Anahuac, TX, published on January 28, 2011. This notice removes the... are withdrawing the proposed rule for Republic Services, Inc./BFI Gulf West Landfill (Gulf West... Environmental protection, Hazardous waste, Recycling, Reporting and recordkeeping requirements. Authority: Sec...

  4. 77 FR 12497 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste Exclusion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-01

    ... and disposed in a Subtitle D landfill permitted, licensed, or otherwise authorized by a State to... satisfied. ConocoPhillips must dispose of this waste in a Subtitle D landfill permitted, licensed or... protection, Hazardous waste, Recycling, Reporting and recordkeeping requirements. Authority: RCRA 3001(f), 42...

  5. 75 FR 61356 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... implications. It will not have substantial direct effects on the States, on the relationship between the... Act of 1996, generally provides that before a rule may take effect, the agency promulgating the rule... protection, Hazardous waste, Recycling, Reporting and recordkeeping requirements. Authority: Sec. 3001(f...

  6. Identification and Listing of Hazardous Waste - CERCLA Hazardous Substance Designation - Reportable Quantity Adjustment - Coke By-Products Wastes - Federal Register Notice, August 18, 1992

    EPA Pesticide Factsheets

    EPA is amending its regulations under the Resource Conservation and Recovery Act (RCRA) by listing as hazardous seven wastes generated during the production, recovery, and refining of coke by-products produced from coal.

  7. A GHS-consistent approach to health hazard classification of petroleum substances, a class of UVCB substances.

    PubMed

    Clark, Charles R; McKee, Richard H; Freeman, James J; Swick, Derek; Mahagaokar, Suneeta; Pigram, Glenda; Roberts, Linda G; Smulders, Chantal J; Beatty, Patrick W

    2013-12-01

    The process streams refined from petroleum crude oil for use in petroleum products are among those designated by USEPA as UVCB substances (unknown or variable composition, complex reaction products and biological materials). They are identified on global chemical inventories with unique Chemical Abstract Services (CAS) numbers and names. The chemical complexity of most petroleum substances presents challenges when evaluating their hazards and can result in differing evaluations due to the varying level of hazardous constituents and differences in national chemical control regulations. Global efforts to harmonize the identification of chemical hazards are aimed at promoting the use of consistent hazard evaluation criteria. This paper discusses a systematic approach for the health hazard evaluation of petroleum substances using chemical categories and the United Nations (UN) Globally Harmonized System (GHS) of classification and labeling. Also described are historical efforts to characterize the hazard of these substances and how they led to the development of categories, the identification of potentially hazardous constituents which should be considered, and a summary of the toxicology of the major petroleum product groups. The use of these categories can increase the utility of existing data, provide better informed hazard evaluations, and reduce the amount of animal testing required. Copyright © 2013 The Authors. Published by Elsevier Inc. All rights reserved.

  8. Locating Errors Through Networked Surveillance: A Multimethod Approach to Peer Assessment, Hazard Identification, and Prioritization of Patient Safety Efforts in Cardiac Surgery.

    PubMed

    Thompson, David A; Marsteller, Jill A; Pronovost, Peter J; Gurses, Ayse; Lubomski, Lisa H; Goeschel, Christine A; Gosbee, John W; Wahr, Joyce; Martinez, Elizabeth A

    2015-09-01

    The objectives were to develop a scientifically sound and feasible peer-to-peer assessment model that allows health-care organizations to evaluate patient safety in cardiovascular operating rooms and to establish safety priorities for improvement. The locating errors through networked surveillance study was conducted to identify hazards in cardiac surgical care. A multidisciplinary team, composed of organizational sociology, organizational psychology, applied social psychology, clinical medicine, human factors engineering, and health services researchers, conducted the study. We used a transdisciplinary approach, which integrated the theories, concepts, and methods from each discipline, to develop comprehensive research methods. Multiple data collection was involved: focused literature review of cardiac surgery-related adverse events, retrospective analysis of cardiovascular events from a national database in the United Kingdom, and prospective peer assessment at 5 sites, involving survey assessments, structured interviews, direct observations, and contextual inquiries. A nominal group methodology, where one single group acts to problem solve and make decisions was used to review the data and develop a list of the top priority hazards. The top 6 priority hazard themes were as follows: safety culture, teamwork and communication, infection prevention, transitions of care, failure to adhere to practices or policies, and operating room layout and equipment. We integrated the theories and methods of a diverse group of researchers to identify a broad range of hazards and good clinical practices within the cardiovascular surgical operating room. Our findings were the basis for a plan to prioritize improvements in cardiac surgical care. These study methods allowed for the comprehensive assessment of a high-risk clinical setting that may translate to other clinical settings.

  9. Rock cliffs hazard analysis based on remote geostructural surveys: The Campione del Garda case study (Lake Garda, Northern Italy)

    NASA Astrophysics Data System (ADS)

    Ferrero, A. M.; Migliazza, M.; Roncella, R.; Segalini, A.

    2011-02-01

    The town of Campione del Garda (located on the west coast of Lake Garda) and its access road have been historically subject to rockfall phenomena with risk for public security in several areas of the coast. This paper presents a study devoted to the determination of risk for coastal cliffs and the design of mitigation measures. Our study was based on statistical rockfall analysis performed with a commercial code and on stability analysis of rock slopes based on the key block method. Hazard from block kinematics and rock-slope failure are coupled by applying the Rockfall Hazard Assessment Procedure (RHAP). Because of the huge dimensions of the slope, its morphology and the geostructural survey were particularly complicated and demanding. For these reasons, noncontact measurement methods, based on aerial photogrammetry by helicopter, were adopted. A special software program, developed by the authors, was applied for discontinuity identification and for their orientation measurements. The potentially of aerial photogrammetic survey in rock mechanic application and its improvement in the rock mass knowledge is analysed in the article.

  10. A fault tree model to assess probability of contaminant discharge from shipwrecks.

    PubMed

    Landquist, H; Rosén, L; Lindhe, A; Norberg, T; Hassellöv, I-M; Lindgren, J F; Dahllöf, I

    2014-11-15

    Shipwrecks on the sea floor around the world may contain hazardous substances that can cause harm to the marine environment. Today there are no comprehensive methods for environmental risk assessment of shipwrecks, and thus there is poor support for decision-making on prioritization of mitigation measures. The purpose of this study was to develop a tool for quantitative risk estimation of potentially polluting shipwrecks, and in particular an estimation of the annual probability of hazardous substance discharge. The assessment of the probability of discharge is performed using fault tree analysis, facilitating quantification of the probability with respect to a set of identified hazardous events. This approach enables a structured assessment providing transparent uncertainty and sensitivity analyses. The model facilitates quantification of risk, quantification of the uncertainties in the risk calculation and identification of parameters to be investigated further in order to obtain a more reliable risk calculation. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. Defining Human Failure Events for Petroleum Risk Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ronald L. Boring; Knut Øien

    2014-06-01

    In this paper, an identification and description of barriers and human failure events (HFEs) for human reliability analysis (HRA) is performed. The barriers, called target systems, are identified from risk significant accident scenarios represented as defined situations of hazard and accident (DSHAs). This report serves as the foundation for further work to develop petroleum HFEs compatible with the SPAR-H method and intended for reuse in future HRAs.

  12. Concern-driven integrated approaches for the grouping, testing and assessment of nanomaterials.

    PubMed

    Landsiedel, Robert

    2016-11-01

    NM's potential to induce adverse effects in humans or the environment is being addressed in numerous research projects, and methods and tools for NM hazard identification and risk assessment are advancing. This article describes how integrated approaches for the testing and assessment of NMs can ensure the safety of nanomaterials, while adhering to the 3Rs principle. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. PROSPECT: Profiling of Resistance Patterns & Oncogenic Signaling Pathways in Evaluation of Cancers of the Thorax and Therapeutic Target Identification

    DTIC Science & Technology

    2012-06-01

    neoadjuvant therapies on disease-free, progression-free, and overall survival will vary across prognostically distinct groups. 3. Specific molecular... prognostically distinct subpopulations of patients with resectable NSCLC, and to assess the extent to which these molecular profiles correlate with tumor...overall survival, and will use Cox proportional hazards models and recursive partitioning methods to identify important biomarkers and prognostically

  14. Risk assessment of hazardous release in air due to the chemical production of "P. Karaminchev" company in the town of Rousse.

    PubMed

    Diankova, M

    1998-09-01

    A health risk evaluation of the lifetime population risk has been made, by using the US EPA's method of risk assessment. Several main steps have been conducted: --a hazard identification, by means of emission analysis and mathematical modeling of air concentration dispersion; a dose-response evaluation and exposure assessment, and finally--a risk characterization. The health risk evaluation was conducted, using lifetime reference concentrations and doses. As risk descriptors were applied: --the individual exposure coefficient (IEC), the hazard quotient (HQ) and the margin of exposure (MOE)--for system toxicants, and the excess lifetime cancer risk (ELCR)--for carcinogens. The method that was used provides an upperbound estimate, including all possible exposures. The results showed, that the emissions of hydrogen chloride, phthalates (DOF), nitrogen oxides and most of the organic solvents, released from this chemical plant, are not a source of lifetime chronic health risk for the population of any of the six evaluated residential areas of Rousse. The rest of the hazardous emissions cause a slightly increased lifetime health risk, which is entirely in the so called 'controlled risk zone' the risk descriptors vary from 1.00 to 5.00. A number of actions have been prescribed to the plant's government, most of which were realized in the short term.

  15. Decreases in self-reported alcohol consumption following HIV counseling and testing at Mulago Hospital, Kampala, Uganda

    PubMed Central

    2014-01-01

    Background Alcohol use has a detrimental impact on the HIV epidemic, especially in sub-Saharan Africa. HIV counseling and testing (HCT) may provide a contact opportunity to intervene with hazardous alcohol use; however, little is known about how alcohol consumption changes following HCT. Methods We utilized data from 2056 participants of a randomized controlled trial comparing two methods of HCT and subsequent linkage to HIV care conducted at Mulago Hospital in Kampala, Uganda. Those who had not previously tested positive for HIV and whose last HIV test was at least one year in the past were eligible. Participants were asked at baseline when they last consumed alcohol, and prior three month alcohol consumption was measured using the Alcohol Use Disorders Identification Test – Consumption (AUDIT-C) at baseline and quarterly for one year. Hazardous alcohol consumption was defined as scoring ≥3 or ≥4 for women and men, respectively. We examined correlates of alcohol use at baseline, and of hazardous and non-hazardous drinking during the year of follow-up using multinomial logistic regression, clustered at the participant level to account for repeated measurements. Results Prior to HCT, 30% were current drinkers (prior three months), 27% were past drinkers (>3 months ago), and 44% were lifetime abstainers. One-third (35%) of the current drinkers met criteria for hazardous drinking. Hazardous and non-hazardous self-reported alcohol consumption declined after HCT, with 16% of baseline current drinkers reporting hazardous alcohol use 3 months after HCT. Independent predictors (p < 0.05) of continuing non-hazardous and hazardous alcohol consumption after HCT were sex (male), alcohol consumption prior to HCT (hazardous), and HIV status (negative). Among those with HIV, non-hazardous drinking was less likely among those taking antiretroviral therapy (ART). Conclusions HCT may be an opportune time to intervene with alcohol consumption. Those with HIV experienced greater declines in alcohol consumption after HCT, and non-hazardous drinking decreased for those with HIV initiating ART. HCT and ART initiation may be ideal times to intervene with alcohol consumption. Screening and brief intervention (SBI) to reduce alcohol consumption should be considered for HCT and HIV treatment venues. PMID:25038830

  16. 29 CFR 1910.144 - Safety color code for marking physical hazards.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 5 2013-07-01 2013-07-01 false Safety color code for marking physical hazards. 1910.144... § 1910.144 Safety color code for marking physical hazards. (a) Color identification—(1) Red. Red shall be the basic color for the identification of: (i) Fire protection equipment and apparatus. [Reserved] (ii...

  17. 29 CFR 1910.144 - Safety color code for marking physical hazards.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 5 2014-07-01 2014-07-01 false Safety color code for marking physical hazards. 1910.144... § 1910.144 Safety color code for marking physical hazards. (a) Color identification—(1) Red. Red shall be the basic color for the identification of: (i) Fire protection equipment and apparatus. [Reserved] (ii...

  18. 29 CFR 1910.144 - Safety color code for marking physical hazards.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 5 2012-07-01 2012-07-01 false Safety color code for marking physical hazards. 1910.144... § 1910.144 Safety color code for marking physical hazards. (a) Color identification—(1) Red. Red shall be the basic color for the identification of: (i) Fire protection equipment and apparatus. [Reserved] (ii...

  19. Approaches to systematic assessment of environmental exposures posed at hazardous waste sites in the developing world: the Toxic Sites Identification Program.

    PubMed

    Ericson, Bret; Caravanos, Jack; Chatham-Stephens, Kevin; Landrigan, Philip; Fuller, Richard

    2013-02-01

    In the developing world, environmental chemical exposures due to hazardous waste sites are poorly documented. We describe the approach taken by the Blacksmith Institute's Toxic Sites Identification Program in documenting environmental chemical exposures due to hazardous waste sites globally, identifying sites of concern and quantifying pathways, populations, and severity of exposure. A network of local environmental investigators was identified and trained to conduct hazardous waste site investigations and assessments. To date, 2,095 contaminated sites have been identified within 47 countries having an estimated population at risk of 71,500,000. Trained researchers and investigators have visited 1,400 of those sites. Heavy metals are the leading primary exposures, with water supply and ambient air being the primary routes of exposure. Even though chemical production has occurred largely in the developed world to date, many hazardous waste sites in the developing world pose significant hazards to the health of large portions of the population. Further research is needed to quantify potential health and economic consequences and identify cost-effective approaches to remediation.

  20. An in vitro human skin test for assessing sensitization potential.

    PubMed

    Ahmed, S S; Wang, X N; Fielding, M; Kerry, A; Dickinson, I; Munuswamy, R; Kimber, I; Dickinson, A M

    2016-05-01

    Sensitization to chemicals resulting in an allergy is an important health issue. The current gold-standard method for identification and characterization of skin-sensitizing chemicals was the mouse local lymph node assay (LLNA). However, for a number of reasons there has been an increasing imperative to develop alternative approaches to hazard identification that do not require the use of animals. Here we describe a human in-vitro skin explant test for identification of sensitization hazards and the assessment of relative skin sensitizing potency. This method measures histological damage in human skin as a readout of the immune response induced by the test material. Using this approach we have measured responses to 44 chemicals including skin sensitizers, pre/pro-haptens, respiratory sensitizers, non-sensitizing chemicals (including skin-irritants) and previously misclassified compounds. Based on comparisons with the LLNA, the skin explant test gave 95% specificity, 95% sensitivity, 95% concordance with a correlation coefficient of 0.9. The same specificity and sensitivity were achieved for comparison of results with published human sensitization data with a correlation coefficient of 0.91. The test also successfully identified nickel sulphate as a human skin sensitizer, which was misclassified as negative in the LLNA. In addition, sensitizers and non-sensitizers identified as positive or negative by the skin explant test have induced high/low T cell proliferation and IFNγ production, respectively. Collectively, the data suggests the human in-vitro skin explant test could provide the basis for a novel approach for characterization of the sensitizing activity as a first step in the risk assessment process. Copyright © 2015 John Wiley & Sons, Ltd.

  1. Rapid screening and identification of chemical hazards in surface and drinking water using high resolution mass spectrometry and a case-control filter.

    PubMed

    Kaserzon, Sarit L; Heffernan, Amy L; Thompson, Kristie; Mueller, Jochen F; Gomez Ramos, Maria Jose

    2017-09-01

    Access to clean, safe drinking water poses a serious challenge to regulators, and requires analytical strategies capable of rapid screening and identification of potentially hazardous chemicals, specifically in situations when threats to water quality or security require rapid investigations and potential response. This study describes a fast and efficient chemical hazard screening strategy for characterising trace levels of polar organic contaminants in water matrices, based on liquid chromatography high resolution mass spectrometry with post-acquisition 'case-control' data processing. This method allowed for a rapid response time of less than 24 h for the screening of target, suspect and non-target unknown chemicals via direct injection analysis, and a second, more sensitive analysis option requiring sample pre-concentration. The method was validated by fortifying samples with a range of pesticides, pharmaceuticals and personal care products (n = 46); with >90% of target compounds positively screened in samples at 1 ng mL -1 , and 46% at 0.1 ng mL -1 when analysed via direct injection. To simulate a contamination event samples were fortified with compounds not present in the commercial library (designated 'non-target compounds'; fipronil and fenitrothion), tentatively identified at 0.2 and 1 ng mL -1 , respectively; and a compound not included in any known commercial library or public database (designated 'unknown' compounds; 8Cl - perfluorooctanesulfonic acid), at 0.8 ng mL -1 . The method was applied to two 'real-case' scenarios: (1) the assessment of drinking water safety during a high-profile event in Brisbane, Australia; and (2) to screen treated, re-circulated drinking water and pre-treated (raw) water. The validated workflow was effective for rapid prioritisation and screening of suspect and non-target potential hazards at trace levels, and could be applied to a wide range of matrices and investigations where comparison of organic contaminants between an affected and control site and or timeframe is warranted. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Bioassay selection, experimental design and quality control/assurance for use in effluent assessment and control.

    PubMed

    Johnson, Ian; Hutchings, Matt; Benstead, Rachel; Thain, John; Whitehouse, Paul

    2004-07-01

    In the UK Direct Toxicity Assessment Programme, carried out in 1998-2000, a series of internationally recognised short-term toxicity test methods for algae, invertebrates and fishes, and rapid methods (ECLOX and Microtox) were used extensively. Abbreviated versions of conventional tests (algal growth inhibition tests, Daphnia magna immobilisation test and the oyster embryo-larval development test) were valuable for toxicity screening of effluent discharges and the identification of causes and sources of toxicity. Rapid methods based on chemiluminescence and bioluminescence were not generally useful in this programme, but may have a role where the rapid test has been shown to be an acceptable surrogate for a standardised test method. A range of quality assurance and control measures were identified. Requirements for quality control/assurance are most stringent when deriving data for characterising the toxic hazards of effluents and monitoring compliance against a toxicity reduction target. Lower quality control/assurance requirements can be applied to discharge screening and the identification of causes and sources of toxicity.

  3. The role of models in estimating consequences as part of the risk assessment process.

    PubMed

    Forde-Folle, K; Mitchell, D; Zepeda, C

    2011-08-01

    The degree of disease risk represented by the introduction, spread, or establishment of one or several diseases through the importation of animals and animal products is assessed by importing countries through an analysis of risk. The components of a risk analysis include hazard identification, risk assessment, risk management, and risk communication. A risk assessment starts with identification of the hazard(s) and then continues with four interrelated steps: release assessment, exposure assessment, consequence assessment, and risk estimation. Risk assessments may be either qualitative or quantitative. This paper describes how, through the integration of epidemiological and economic models, the potential adverse biological and economic consequences of exposure can be quantified.

  4. Simulating geriatric home safety assessments in a three-dimensional virtual world.

    PubMed

    Andrade, Allen D; Cifuentes, Pedro; Mintzer, Michael J; Roos, Bernard A; Anam, Ramanakumar; Ruiz, Jorge G

    2012-01-01

    Virtual worlds could offer inexpensive and safe three-dimensional environments in which medical trainees can learn to identify home safety hazards. Our aim was to evaluate the feasibility, usability, and acceptability of virtual worlds for geriatric home safety assessments and to correlate performance efficiency in hazard identification with spatial ability, self-efficacy, cognitive load, and presence. In this study, 30 medical trainees found the home safety simulation easy to use, and their self-efficacy was improved. Men performed better than women in hazard identification. Presence and spatial ability were correlated significantly with performance. Educators should consider spatial ability and gender differences when implementing virtual world training for geriatric home safety assessments.

  5. DEM-based Approaches for the Identification of Flood Prone Areas

    NASA Astrophysics Data System (ADS)

    Samela, Caterina; Manfreda, Salvatore; Nardi, Fernando; Grimaldi, Salvatore; Roth, Giorgio; Sole, Aurelia

    2013-04-01

    The remarkable number of inundations that caused, in the last decades, thousands of deaths and huge economic losses, testifies the extreme vulnerability of many Countries to the flood hazard. As a matter of fact, human activities are often developed in the floodplains, creating conditions of extremely high risk. Terrain morphology plays an important role in understanding, modelling and analyzing the hydraulic behaviour of flood waves. Research during the last 10 years has shown that the delineation of flood prone areas can be carried out using fast methods that relay on basin geomorphologic features. In fact, the availability of new technologies to measure surface elevation (e.g., GPS, SAR, SAR interferometry, RADAR and LASER altimetry) has given a strong impulse to the development of Digital Elevation Models (DEMs) based approaches. The identification of the dominant topographic controls on the flood inundation process is a critical research question that we try to tackle with a comparative analysis of several techniques. We reviewed four different approaches for the morphological characterization of a river basin with the aim to provide a description of their performances and to identify their range of applicability. In particular, we explored the potential of the following tools. 1) The hydrogeomorphic method proposed by Nardi et al. (2006) which defines the flood prone areas according to the water level in the river network through the hydrogeomorphic theory. 2) The linear binary classifier proposed by Degiorgis et al. (2012) which allows distinguishing flood-prone areas using two features related to the location of the site under exam with respect to the nearest hazard source. The two features, proposed in the study, are the length of the path that hydrologically connects the location under exam to the nearest element of the drainage network and the difference in elevation between the cell under exam and the final point of the same path. 3) The method by Manfreda et al. (2011) that suggested a modified Topographic Index (TIm) for the identification of flood prone area. 4) The downslope index proposed by Hjerdt et al. (2004) that quantifies the topographic controls on hydrology by evaluating head differences following the (surface) flow path in the steepest direction. The method does not use the exit point at the stream as reference; instead, the algorithm looks at how far a parcel of water has to travel along its flow path to lose a given head potential, d [m]. This last index was not defined with the aim to describe flood prone areas; in fact it represents an interesting alternative descriptor of morphological features that deserve to be tested. Analyses have been carried out for some Italian catchments. The outcomes of the four methods are presented using, for calibration and validation purposes, flood inundation maps made available by River Basin Authorities. The aim is, therefore, to evaluate the reliability and the relative errors in the detection of the areas subject to the flooding hazard. These techniques should not be considered as an alternative of traditional procedures, but additional tool for the identification of flood-prone areas and hazard graduation over large regions or when a preliminary identification is needed. Reference Degiorgis M., G. Gnecco, S. Gorni, G. Roth, M. Sanguineti, A. C. Taramasso, Classifiers for the detection of flood-prone areas using remote sensed elevation data, J. Hydrol., 470-471, 302-315, 2012. Hjerdt, K. N., J. J. McDonnell, J. Seibert, A. Rodhe, A new topographic index to quantify downslope controls on local drainage, Water Resour. Res., 40, W05602, 2004. Manfreda, S., M. Di Leo, A. Sole, Detection of Flood Prone Areas using Digital Elevation Models, Journal of Hydrologic Engineering, Vol. 16, No. 10, 781-790, 2011. Nardi, F., E. R. Vivoni, S. Grimaldi, Investigating a floodplain scaling relation using a hydrogeomorphic delineation method, Water Resour. Res., 42, W09409, 2006.

  6. Towards a Proactive Risk Mitigation Strategy at La Fossa Volcano, Vulcano Island

    NASA Astrophysics Data System (ADS)

    Biass, S.; Gregg, C. E.; Frischknecht, C.; Falcone, J. L.; Lestuzzi, P.; di Traglia, F.; Rosi, M.; Bonadonna, C.

    2014-12-01

    A comprehensive risk assessment framework was built to develop proactive risk reduction measures for Vulcano Island, Italy. This framework includes identification of eruption scenarios; probabilistic hazard assessment, quantification of hazard impacts on the built environment, accessibility assessment on the island and risk perception study. Vulcano, a 21 km2 island with two primary communities host to 900 permanent residents and up to 10,000 visitors during summer, shows a strong dependency on the mainland for basic needs (water, energy) and relies on a ~2 month tourism season for its economy. The recent stratigraphy reveals a dominance of vulcanian and subplinian eruptions, producing a range of hazards acting at different time scales. We developed new methods to probabilistically quantify the hazard related to ballistics, lahars and tephra for all eruption styles. We also elaborated field- and GIS- based methods to assess the physical vulnerability of the built environment and created dynamic models of accessibility. Results outline the difference of hazard between short and long-lasting eruptions. A subplinian eruption has a 50% probability of impacting ~30% of the buildings within days after the eruption, but the year-long damage resulting from a long-lasting vulcanian eruption is similar if tephra is not removed from rooftops. Similarly, a subplinian eruption results in a volume of 7x105 m3 of material potentially remobilized into lahars soon after the eruption. Similar volumes are expected for a vulcanian activity over years, increasing the hazard of small lahars. Preferential lahar paths affect critical infrastructures lacking redundancy, such as the road network, communications systems, the island's only gas station, and access to the island's two evacuation ports. Such results from hazard, physical and systemic vulnerability help establish proactive volcanic risk mitigation strategies and may be applicable in other island settings.

  7. NASA Safety Manual. Volume 3: System Safety

    NASA Technical Reports Server (NTRS)

    1970-01-01

    This Volume 3 of the NASA Safety Manual sets forth the basic elements and techniques for managing a system safety program and the technical methods recommended for use in developing a risk evaluation program that is oriented to the identification of hazards in aerospace hardware systems and the development of residual risk management information for the program manager that is based on the hazards identified. The methods and techniques described in this volume are in consonance with the requirements set forth in NHB 1700.1 (VI), Chapter 3. This volume and future volumes of the NASA Safety Manual shall not be rewritten, reprinted, or reproduced in any manner. Installation implementing procedures, if necessary, shall be inserted as page supplements in accordance with the provisions of Appendix A. No portion of this volume or future volumes of the NASA Safety Manual shall be invoked in contracts.

  8. The Typhoon Disaster Analysis Based on Weibo Topic Heat

    NASA Astrophysics Data System (ADS)

    Yuan, J.; Gong, A.; Wang, J.; Li, J.

    2018-04-01

    Could social media data be utilized in hazard evaluation? Typhoon disaster as one of the costly disaster has become devastating threats for human. Moreover, social media change the communication way of human and citizens can turn to this platform to express disasterrelated information at real time. Therefore, social media improves situational awareness and widens the method of hazard information acquiring. With more and more studies investigating in relationship between social media response and degree of damage, the strong correlation has been proved. Weibo as one of the most popular social media in China can provide data with posted text, location, user identification and other additional information. Combining with 10 tropical cyclones and Weibo data in 2013, We perform a quantitative analysis between the grade of hazard situation and Weibo related topic heat in province scale. We provide a new model of Weibo topic heat to evaluate the Weibo activity in study area. Also we demonstrate the hazard assessing formula is H = 1.8845 ln(α) + 15.636 in tropical cyclone disaster. High level goodness of curve fitting also suggest that this equation can be used for rapid assessment of hazard caused by tropical cyclones.

  9. Hydrothermal Liquefaction Treatment Preliminary Hazard Analysis Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lowry, Peter P.; Wagner, Katie A.

    A preliminary hazard assessment was completed during February 2015 to evaluate the conceptual design of the modular hydrothermal liquefaction treatment system. The hazard assessment was performed in 2 stages. An initial assessment utilizing Hazard Identification and Preliminary Hazards Analysis (PHA) techniques identified areas with significant or unique hazards (process safety-related hazards) that fall outside of the normal operating envelope of PNNL and warranted additional analysis. The subsequent assessment was based on a qualitative What-If analysis. This analysis was augmented, as necessary, by additional quantitative analysis for scenarios involving a release of hazardous material or energy with the potential for affectingmore » the public.« less

  10. 40 CFR 279.43 - Used oil transportation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... identification number; (2) A used oil processing/re-refining facility who has obtained an EPA identification number; (3) An off-specification used oil burner facility who has obtained an EPA identification number... parts 171 through 180. Persons transporting used oil that meets the definition of a hazardous material...

  11. 40 CFR 279.43 - Used oil transportation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... identification number; (2) A used oil processing/re-refining facility who has obtained an EPA identification number; (3) An off-specification used oil burner facility who has obtained an EPA identification number... parts 171 through 180. Persons transporting used oil that meets the definition of a hazardous material...

  12. Rossitsa River Basin: Flood Hazard and Risk Identification

    NASA Astrophysics Data System (ADS)

    Mavrova-Guirguinova, Maria; Pencheva, Denislava

    2017-04-01

    The process of Flood Risk Management Planning and adaptation of measures for flood risk reduction as the Early Warning provoke the necessity of surveys involving Identification aspects. This project presents risk identification combining two lines of analysis: (1) Creation a mathematical model of rainfall-runoff processes in a watershed based on limited number of observed input and output variables; (2) Procedures for determination of critical thresholds - discharges/water levels corresponding to certain consequences. The pilot region is Rossitsa river basin, Sevlievo, Bulgaria. The first line of analysis follows next steps: (a) Creation and calibration of Unit Hydrograph Models based on limited number of observed data for discharge and precipitation; The survey at the selected region has 22 observations for excess rainfall and discharge. (b) The relations of UHM coefficients from the input parameters have been determined statistically, excluding the ANN model of the run-off coefficient as a function of 3 parameters (amount of precipitation two days before, soil condition, intensity of the rainfall) where a feedforward neural network is used. (c) Additional simulations with UHM aiming at generation of synthetic data for rainfall-runoff events, which extend the range of observed data; (d) Training, validation and testing a generalized regional ANN Model for discharge forecasting with 4 input parameters, where the training data set consists of synthetic data, validation and testing data sets consists of observations. A function between consequences and discharges has been reached in the second line of analysis concerning critical hazard levels determination. Unsteady simulations with the hydraulic model using three typical hydrographs for determination of the existing time for reaction from one to upper critical threshold are made. Correction of the critical thresholds aiming at providing necessary time for reaction between the thresholds and probability analysis of the finally determined critical thresholds are made. The result of the described method is a Catalogue for off-line flood hazard and risk identification. It can be used as interactive computer system, based on simulations of the ANN "Catalogue". Flood risk identification of the future rainfall event is made in a multi-dimensional space for each kind of soil conditions (dry, average wet and wet condition) and observed amount of precipitation two days before. Rainfall-runoff scenarios in case of intensive rainfall or sustained rainfall (more than 6 hours) are taken into account. Critical thresholds and hazard zones needed of specific operative activities (rescue and recovery) corresponded to each of the regulated flood protection levels (unite, municipality, regional or national) are presented. The Catalogue gives the opportunity for flood hazard scenarios extraction. Regarding that, the Catalogue is useful on the prevention stage of flood protection planning (emergency operations, measures and resources for their implementation planning) and creation of scenarios for training the Emergency Plans. Concerning application for Early Warning, it gives approximate forecast for flood hazard. The Catalogue supplies the necessary time for reaction of about 24 hours. Thus, Early Warning is possible to the responsible authorities, all parts if the Unified Rescue System, members of suitable Headquarters for disaster protection (on municipality, region or national level).

  13. Comparative risk analysis of technological hazards (a review).

    PubMed Central

    Kates, R W; Kasperson, J X

    1983-01-01

    Hazards are threats to people and what they value and risks are measures of hazards. Comparative analyses of the risks and hazards of technology can be dated to Starr's 1969 paper [Starr, C. (1969) Science 165, 1232-1238] but are rooted in recent trends in the evolution of technology, the identification of hazard, the perception of risk, and the activities of society. These trends have spawned an interdisciplinary quasi profession with new terminology, methodology, and literature. A review of 54 English-language monographs and book-length collections, published between 1970 and 1983, identified seven recurring themes: (i) overviews of the field of risk assessment, (ii) efforts to estimate and quantify risk, (iii) discussions of risk acceptability, (iv) perception, (v) analyses of regulation, (vi) case studies of specific technological hazards, and (vii) agenda for research. Within this field, science occupies a unique niche, for many technological hazards transcend the realm of ordinary experience and require expert study. Scientists can make unique contributions to each area of hazard management but their primary contribution is the practice of basic science. Beyond that, science needs to further risk assessment by understanding the more subtle processes of hazard creation and by establishing conventions for estimating risk and for presenting and handling uncertainty. Scientists can enlighten the discussion of tolerable risk by setting risks into comparative contexts, by studying the process of evaluation, and by participating as knowledgeable individuals, but they cannot decide the issue. Science can inform the hazard management process by broadening the range of alternative control actions and modes of implementation and by devising methods to evaluate their effectiveness. PMID:6580625

  14. Hazardous Waste Management System: Identification and Listing of Hazardous Waste - CERCLA Hazardous Substance Designation-Petroleum Refinery Primary and Other Listings (F037 and F038) - Federal Register Notice, May 13, 1991

    EPA Pesticide Factsheets

    The Agency is promulgating an interim final rule revising the definition of wastes subject to the F037 and F038 listings to state that sludges from non-contact, once-through cooling waters are not included.

  15. Effectiveness of a Web-Based Intervention to Reduce Alcohol Consumption among French Hazardous Drinkers: A Randomized Controlled Trial

    ERIC Educational Resources Information Center

    Guillemont, Juliette; Cogordan, Chloé; Nalpas, Bertrand; Nguyen-Thanh, Vi?t; Richard, Jean-Baptiste; Arwidson, Pierre

    2017-01-01

    This study aims to evaluate the effectiveness of a web-based intervention to reduce alcohol consumption among hazardous drinkers. A two-group parallel randomized controlled trial was conducted among adults identified as hazardous drinkers according to the Alcohol Use Disorders Identification Test. The intervention delivers personalized normative…

  16. 77 FR 43002 - Hazardous Waste Management System: Identification and Listing of Hazardous Waste Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ... Subjects in 40 CFR Part 261 Environmental protection, Hazardous waste, Recycling, and Reporting and... a maximum annual rate of 200 cubic yards per year must be disposed in a lined Subtitle D landfill... forth in paragraph 1, Phillips 66 can dispose of the processed sludge in a lined Subtitle D landfill...

  17. 76 FR 5110 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Proposed Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-28

    ... submitted by Gulf West Landfill, TX, LP. (Gulf West) to exclude (or delist) the landfill leachate generated..../BFI Gulf West Landfill petition, contact Michelle Peace at 214-665-7430 or by e-mail at peace.michelle... its landfill excluded, or delisted from the definition of a hazardous waste. The leachate derived from...

  18. 75 FR 71559 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Withdrawal of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ...Mobil Refining and Supply Company-- Beaumont Refinery, published on October 1, 2010. DATES: Effective...: Because EPA received adverse comments, we are withdrawing the direct final exclusion for ExxonMobil...

  19. 75 FR 51671 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Final Exclusion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... wastewater treatment plant (WWTP) sludge filter cake (called sludge hereinafter) generated by Tokusen in... brass coating. The facility generates F006 filter cake by the dewatering of wastewater sludge generated...

  20. Installation-restoration program. Preliminary assessment: 106th Civil Engineering Flight, Roslyn Air National Guard Station, New York Air National Guard, Roslyn, New York

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1991-02-01

    The preliminary assessment included the following activities: (1) An on-site visit, including interviews and field surveys; (2) Acquisition and analysis of information on past hazardous materials use, waste generation, and waste disposal at the Station; (3) Acquisition and analysis of available geological surveys, hydrological data, meteorological data, and environmental data; and (4) The identification and assessment of sites where contamination of soils, ground water and/or surface water may have occurred. Operations that have involved the use of hazardous materials and the disposal of hazardous wastes include vehicle maintenance and aerospace ground equipment (AGE) maintenance. The hazardous wastes disposed fo throughmore » these operations include varying quantities of petroleum-oil-lubricant (POL) products, acids, paints, thinners, strippers, and solvents. The field surveys and interviews resulted in the identification of three sites that exhibit the potential for migration of contaminants.« less

  1. Rapid detection of hazardous chemicals in textiles by direct analysis in real-time mass spectrometry (DART-MS).

    PubMed

    Antal, Borbála; Kuki, Ákos; Nagy, Lajos; Nagy, Tibor; Zsuga, Miklós; Kéki, Sándor

    2016-07-01

    Residues of chemicals on clothing products were examined by direct analysis in real-time (DART) mass spectrometry. Our experiments have revealed the presence of more than 40 chemicals in 15 different clothing items. The identification was confirmed by DART tandem mass spectrometry (MS/MS) experiments for 14 compounds. The most commonly detected hazardous substances were nonylphenol ethoxylates (NPEs), phthalic acid esters (phthalates), amines released by azo dyes, and quinoline derivates. DART-MS was able to detect NPEs on the skin of the person wearing the clothing item contaminated by NPE residuals. Automated data acquisition and processing method was developed and tested for the recognition of NPE residues thereby reducing the analysis time.

  2. 43 CFR 11.25 - Preassessment screen-preliminary identification of resources potentially at risk.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... pathways. (1) The authorized official shall make a preliminary identification of potential exposure pathways to facilitate identification of resources at risk. (2) Factors to be considered in this... toxicological properties of the oil or hazardous substance. (3) Pathways to be considered shall include, as...

  3. 43 CFR 11.25 - Preassessment screen-preliminary identification of resources potentially at risk.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... pathways. (1) The authorized official shall make a preliminary identification of potential exposure pathways to facilitate identification of resources at risk. (2) Factors to be considered in this... toxicological properties of the oil or hazardous substance. (3) Pathways to be considered shall include, as...

  4. 43 CFR 11.25 - Preassessment screen-preliminary identification of resources potentially at risk.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... pathways. (1) The authorized official shall make a preliminary identification of potential exposure pathways to facilitate identification of resources at risk. (2) Factors to be considered in this... toxicological properties of the oil or hazardous substance. (3) Pathways to be considered shall include, as...

  5. 43 CFR 11.25 - Preassessment screen-preliminary identification of resources potentially at risk.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... pathways. (1) The authorized official shall make a preliminary identification of potential exposure pathways to facilitate identification of resources at risk. (2) Factors to be considered in this... toxicological properties of the oil or hazardous substance. (3) Pathways to be considered shall include, as...

  6. 43 CFR 11.25 - Preassessment screen-preliminary identification of resources potentially at risk.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... pathways. (1) The authorized official shall make a preliminary identification of potential exposure pathways to facilitate identification of resources at risk. (2) Factors to be considered in this... toxicological properties of the oil or hazardous substance. (3) Pathways to be considered shall include, as...

  7. In vitro methods for hazard assessment of industrial chemicals – opportunities and challenges

    PubMed Central

    Wong, Chin Lin; Ghassabian, Sussan; Smith, Maree T.; Lam, Ai-Leen

    2015-01-01

    Allergic contact dermatitis (ACD) is a delayed-type hypersensitivity immune reaction mediated by T-lymphocytes as a result of repeated exposure of an allergen primarily on skin. ACD accounts for up to 95% of occupational skin diseases, with epoxy resins implicated as one of the most common causes of ACD. Efficient high-throughput in vitro screening for accurate identification of compounds and materials that may pose hazardous risks in the workplace is crucial. At present, the murine local lymph node assay is the ‘method of choice’ for predicting the sensitizing potency of contact allergens. As the 3Rs principles of reduction, refinement, and replacement in animal testing has gained political and economic momentum, several in vitro screening methods have been developed for identifying potential contact allergens. To date, these latter methods have been utilized primarily to assess the skin sensitizing potential of the chemical components of cosmetic products with scant research attention as to the applicability of these methods to industrial chemicals, particularly epoxy resins. Herein we review the currently utilized in vitro methods and identify the knowledge gaps with regard to assessing the generalizability of in vitro screening methods for assessing the skin sensitizing potential of industrial chemicals. PMID:25999858

  8. In vitro methods for hazard assessment of industrial chemicals - opportunities and challenges.

    PubMed

    Wong, Chin Lin; Ghassabian, Sussan; Smith, Maree T; Lam, Ai-Leen

    2015-01-01

    Allergic contact dermatitis (ACD) is a delayed-type hypersensitivity immune reaction mediated by T-lymphocytes as a result of repeated exposure of an allergen primarily on skin. ACD accounts for up to 95% of occupational skin diseases, with epoxy resins implicated as one of the most common causes of ACD. Efficient high-throughput in vitro screening for accurate identification of compounds and materials that may pose hazardous risks in the workplace is crucial. At present, the murine local lymph node assay is the 'method of choice' for predicting the sensitizing potency of contact allergens. As the 3Rs principles of reduction, refinement, and replacement in animal testing has gained political and economic momentum, several in vitro screening methods have been developed for identifying potential contact allergens. To date, these latter methods have been utilized primarily to assess the skin sensitizing potential of the chemical components of cosmetic products with scant research attention as to the applicability of these methods to industrial chemicals, particularly epoxy resins. Herein we review the currently utilized in vitro methods and identify the knowledge gaps with regard to assessing the generalizability of in vitro screening methods for assessing the skin sensitizing potential of industrial chemicals.

  9. Using In Vitro High-Throughput Screening Data for Predicting Benzo[k]Fluoranthene Human Health Hazards.

    PubMed

    Burgoon, Lyle D; Druwe, Ingrid L; Painter, Kyle; Yost, Erin E

    2017-02-01

    Today there are more than 80,000 chemicals in commerce and the environment. The potential human health risks are unknown for the vast majority of these chemicals as they lack human health risk assessments, toxicity reference values, and risk screening values. We aim to use computational toxicology and quantitative high-throughput screening (qHTS) technologies to fill these data gaps, and begin to prioritize these chemicals for additional assessment. In this pilot, we demonstrate how we were able to identify that benzo[k]fluoranthene may induce DNA damage and steatosis using qHTS data and two separate adverse outcome pathways (AOPs). We also demonstrate how bootstrap natural spline-based meta-regression can be used to integrate data across multiple assay replicates to generate a concentration-response curve. We used this analysis to calculate an in vitro point of departure of 0.751 μM and risk-specific in vitro concentrations of 0.29 μM and 0.28 μM for 1:1,000 and 1:10,000 risk, respectively, for DNA damage. Based on the available evidence, and considering that only a single HSD17B4 assay is available, we have low overall confidence in the steatosis hazard identification. This case study suggests that coupling qHTS assays with AOPs and ontologies will facilitate hazard identification. Combining this with quantitative evidence integration methods, such as bootstrap meta-regression, may allow risk assessors to identify points of departure and risk-specific internal/in vitro concentrations. These results are sufficient to prioritize the chemicals; however, in the longer term we will need to estimate external doses for risk screening purposes, such as through margin of exposure methods. © 2016 Society for Risk Analysis.

  10. Job safety analysis and hazard identification for work accident prevention in para rubber wood sawmills in southern Thailand.

    PubMed

    Thepaksorn, Phayong; Thongjerm, Supawan; Incharoen, Salee; Siriwong, Wattasit; Harada, Kouji; Koizumi, Akio

    2017-11-25

    We utilized job safety analysis (JSA) and hazard identification for work accident prevention in Para rubber wood sawmills, which aimed to investigate occupational health risk exposures and assess the health hazards at sawmills in the Trang Province, located in southern Thailand. We conducted a cross-sectional study which included a walk-through survey, JSA, occupational risk assessment, and environmental samplings from March through September 2015 at four Para rubber wood sawmills. We identified potential occupational safety and health hazards associated with six main processes, including: 1) logging and cutting, 2) sawing the lumber into sheets, 3) planing and re-arranging, 4) vacuuming and wood preservation, 5) drying and planks re-arranging, and 6) grading, packing, and storing. Working in sawmills was associated with high risk of wood dust and noise exposure, occupational accidents injuring hands and feet, chemicals and fungicide exposure, and injury due to poor ergonomics or repetitive work. Several high-risk areas were identified from JSA and hazard identification of the working processes, especially high wood dust and noise exposure when sawing lumber into sheets and risk of occupational accidents of the hands and feet when struck by lumber. All workers were strongly recommended to use personal protective equipment in any working processes. Exposures should be controlled using local ventilation systems and reducing noise transmission. We recommend that the results from the risk assessment performed in this study be used to create an action plan for reducing occupational health hazards in Para rubber sawmills.

  11. Automated Hazard Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Riddle, F. J.

    2003-06-26

    The Automated Hazard Analysis (AHA) application is a software tool used to conduct job hazard screening and analysis of tasks to be performed in Savannah River Site facilities. The AHA application provides a systematic approach to the assessment of safety and environmental hazards associated with specific tasks, and the identification of controls regulations, and other requirements needed to perform those tasks safely. AHA is to be integrated into existing Savannah River site work control and job hazard analysis processes. Utilization of AHA will improve the consistency and completeness of hazard screening and analysis, and increase the effectiveness of the workmore » planning process.« less

  12. 40 CFR 261.140 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Applicability. 261.140 Section 261.140 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Financial Requirements for Management of Excluded Hazardous Secondary...

  13. Federal Register Notice: Identification and Listing of Hazardous Waste from Wood Preserving Operations

    EPA Pesticide Factsheets

    EPA is today amending its regulations under the Resource Conservation and Recovery Act by listing as hazardous three categories of wastes from wood preserving operations that use chlorophenolic, creosote, and/or inorganic preservatives

  14. HAZARD IDENTIFICATION: EFFICIENCY OF SHORT-TERM TESTS IN IDENTIFYING GERM CELL MUTAGENS AND PUTATIVE NONGENOTOXIC CARCINOGENS

    EPA Science Inventory

    For more than a decade, mutagenicity tests have had a clearly defined role in the identification of potential human mutagens and an ancillary role in the identification of potential human carcinogens. he efficiency of short-term tests in identifying germ cell mutagens has been ex...

  15. Local lymph node assay (LLNA) for detection of sensitization capacity of chemicals.

    PubMed

    Gerberick, G Frank; Ryan, Cindy A; Dearman, Rebecca J; Kimber, Ian

    2007-01-01

    The local lymph node assay (LLNA) is a murine model developed to evaluate the skin sensitization potential of chemicals. The LLNA is an alternative approach to traditional guinea pig methods and in comparison provides important animal welfare benefits. The assay relies on measurement of events induced during the induction phase of skin sensitization, specifically lymphocyte proliferation in the draining lymph nodes which is a hallmark of a skin sensitization response. Since its introduction the LLNA has been the subject of extensive evaluation on a national and international scale, and has been successfully validated and incorporated worldwide into regulatory guidelines. Experience gained in recent years has demonstrated that adherence to published procedures and guidelines for the LLNA (e.g., with respect to dose and vehicle selection) is critical for the successful conduct and eventual interpretation of the data. In addition to providing a robust method for skin sensitization hazard identification, the LLNA has proven very useful in assessing the skin sensitizing potency of test chemicals, and this has provided invaluable information to risk assessors. The primary method to make comparisons of the relative potency of chemical sensitizers is to use linear interpolation to estimate the concentration of chemical required to induce a stimulation index of three relative to concurrent vehicle-treated controls (EC3). In certain situations where there are available less than optimal dose response data a log-linear extrapolation method can be used to estimate an EC3 value which can reduce significantly the need for repeat testing of chemicals. The LLNA, when conducted according to published guidelines, provides a robust method for skin sensitization testing that not only provides reliable hazard identification information but also data necessary for effective risk assessment and risk management.

  16. Evaluation of a Parchment Document, the 13th Century Incorporation Charter for the City of Krakow, Poland, for Microbial Hazards

    PubMed Central

    2016-01-01

    The literature of environmental microbiology broadly discusses issues associated with microbial hazards in archives, but these publications are mainly devoted to paper documents. There are few articles on historical parchment documents, which used to be very important for the development of literature and the art of writing. These studies present a broad spectrum of methods for the assessment of biodeterioration hazards of the parchment document in question. They are based on both conventional microbiological methods and advanced techniques of molecular biology. Here, a qualitative analysis was conducted, based on genetic identification of bacteria and fungi present on the document as well as denaturing gradient gel electrophoresis profiling and examining the destructive potential of isolated microbes. Moreover, the study involved a quantitative and qualitative microbiological assessment of the indoor air in the room where the parchment was kept. The microbes with the highest destructive potential that were isolated from the investigated item were Bacillus cereus and Acinetobacter lwoffii bacteria and Penicillium chrysogenum, Chaetomium globosum, and Trichoderma longibrachiatum fungi. The presence of the B. cereus strain was particularly interesting since, under appropriate conditions, it leads to complete parchment degradation within several days. PMID:26896133

  17. Identification and Listing of Hazardous Waste - Wood Preserving - Federal Register Notice, December 6, 1990

    EPA Pesticide Factsheets

    The EPA is amending its regulations under the Resource Conservation and Recovery Act by listing as hazardous three categories of wastes from wood preserving operations that use chlorophenolic, creosote, inorganic (arsenical and chromium) preservatives.

  18. The Future of Hazardous Waste Tracking: Radio Frequency Identification (RFID)

    EPA Science Inventory

    The capability and performance of various RFID technologies to track hazardous wastes and materials (HAZMAT) across international borders will be verified in the El Paso, Texas-Ciudad Juarez, Mexico area under EPA's Environmental Technology Verification (ETV)/Environmental and S...

  19. 40 CFR 261.23 - Characteristic of reactivity.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Section 261.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Characteristics of Hazardous Waste § 261.23 Characteristic of reactivity. (a) A solid waste exhibits the characteristic of reactivity if a representative...

  20. 40 CFR 261.23 - Characteristic of reactivity.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Section 261.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Characteristics of Hazardous Waste § 261.23 Characteristic of reactivity. (a) A solid waste exhibits the characteristic of reactivity if a representative...

  1. 40 CFR 261.23 - Characteristic of reactivity.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Section 261.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Characteristics of Hazardous Waste § 261.23 Characteristic of reactivity. (a) A solid waste exhibits the characteristic of reactivity if a representative...

  2. 40 CFR 261.23 - Characteristic of reactivity.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Section 261.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Characteristics of Hazardous Waste § 261.23 Characteristic of reactivity. (a) A solid waste exhibits the characteristic of reactivity if a representative...

  3. 40 CFR 261.23 - Characteristic of reactivity.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Section 261.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Characteristics of Hazardous Waste § 261.23 Characteristic of reactivity. (a) A solid waste exhibits the characteristic of reactivity if a representative...

  4. 75 FR 16037 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Proposed Exclusion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-31

    ... delist) a wastewater treatment plant (WWTP) sludge filter cake (called just sludge hereinafter) generated... copper and zinc to produce a brass coating. The facility generates F006 filter cake by the dewatering of...

  5. IMMUNE SYSTEM ONTOGENY AND DEVELOPMENTAL IMMUNOTOXICOLOGY

    EPA Science Inventory

    Animal testing for the identification and characterization of hazard(s), associated with exposure to toxic chemicals, is an accepted approach for identifying the potential risk to humans. The rodent, in particular the rat, has been the most commonly used species for routine toxi...

  6. Bacillus "next generation" diagnostics: moving from detection toward subtyping and risk-related strain profiling.

    PubMed

    Ehling-Schulz, Monika; Messelhäusser, Ute

    2013-01-01

    The highly heterogeneous genus Bacillus comprises the largest species group of endospore forming bacteria. Because of their ubiquitous nature, Bacillus spores can enter food production at several stages resulting in significant economic losses and posing a potential risk to consumers due the capacity of certain Bacillus strains for toxin production. In the past, food microbiological diagnostics was focused on the determination of species using conventional culture-based methods, which are still widely used. However, due to the extreme intra-species diversity found in the genus Bacillus, DNA-based identification and typing methods are gaining increasing importance in routine diagnostics. Several studies showed that certain characteristics are rather strain-dependent than species-specific. Therefore, the challenge for current and future Bacillus diagnostics is not only the efficient and accurate identification on species level but also the development of rapid methods to identify strains with specific characteristics (such as stress resistance or spoilage potential), trace contamination sources, and last but not least discriminate potential hazardous strains from non-toxic strains.

  7. [A preliminary mapping methodology for occupational hazards and biomechanical risk evaluation: presentation of a simple, computerized tool kit for ergonomic hazards identification and risk assessment].

    PubMed

    Colombini, Daniela; Occhipinti, E; Di Leone, G

    2011-01-01

    During the last Congress of the International Ergonomics Association (IEA), Beijing, August 2009, an international group was founded with the task of developing a "toolkit for MSD prevention" under the IEA and in collaboration with the World Health Organization. The possible users of toolkits are: members of health and safety committees; health and safety representatives; line supervisors; foremen; workers; government representatives; health workers providing basic occupational health services; occupational health and safety specialists. According to the ISO standard 11228 series and the new Draft CD ISO 12259-2009: Application document guides for the potential user, our group developed a preliminary "mapping" methodology of occupational hazards in the craft industry, supported by software (Excel). The proposed methodology, using specific key enters and quick assessment criteria, allows a simple ergonomics hazards identification and risk estimation to be made. It is thus possible to decide for which occupational hazards a more exhaustive risk assessment will be necessary and which occupational consultant should be involved (occupational physician, safety engineer, industrial hygienist, etc.).

  8. Two-dimensional fuzzy fault tree analysis for chlorine release from a chlor-alkali industry using expert elicitation.

    PubMed

    Renjith, V R; Madhu, G; Nayagam, V Lakshmana Gomathi; Bhasi, A B

    2010-11-15

    The hazards associated with major accident hazard (MAH) industries are fire, explosion and toxic gas releases. Of these, toxic gas release is the worst as it has the potential to cause extensive fatalities. Qualitative and quantitative hazard analyses are essential for the identification and quantification of these hazards related to chemical industries. Fault tree analysis (FTA) is an established technique in hazard identification. This technique has the advantage of being both qualitative and quantitative, if the probabilities and frequencies of the basic events are known. This paper outlines the estimation of the probability of release of chlorine from storage and filling facility of chlor-alkali industry using FTA. An attempt has also been made to arrive at the probability of chlorine release using expert elicitation and proven fuzzy logic technique for Indian conditions. Sensitivity analysis has been done to evaluate the percentage contribution of each basic event that could lead to chlorine release. Two-dimensional fuzzy fault tree analysis (TDFFTA) has been proposed for balancing the hesitation factor involved in expert elicitation. Copyright © 2010 Elsevier B.V. All rights reserved.

  9. Fault Tree Analysis: A Bibliography

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Fault tree analysis is a top-down approach to the identification of process hazards. It is as one of the best methods for systematically identifying an graphically displaying the many ways some things can go wrong. This bibliography references 266 documents in the NASA STI Database that contain the major concepts. fault tree analysis, risk an probability theory, in the basic index or major subject terms. An abstract is included with most citations, followed by the applicable subject terms.

  10. Advanced ultrasonic measurement methodology for non-invasive interrogation and identification of fluids in sealed containers

    NASA Astrophysics Data System (ADS)

    Tucker, Brian J.; Diaz, Aaron A.; Eckenrode, Brian A.

    2006-03-01

    Government agencies and homeland security related organizations have identified the need to develop and establish a wide range of unprecedented capabilities for providing scientific and technical forensic services to investigations involving hazardous chemical, biological, and radiological materials, including extremely dangerous chemical and biological warfare agents. Pacific Northwest National Laboratory (PNNL) has developed a prototype portable, hand-held, hazardous materials acoustic inspection prototype that provides noninvasive container interrogation and material identification capabilities using nondestructive ultrasonic velocity and attenuation measurements. Due to the wide variety of fluids as well as container sizes and materials encountered in various law enforcement inspection activities, the need for high measurement sensitivity and advanced ultrasonic measurement techniques were identified. The prototype was developed using a versatile electronics platform, advanced ultrasonic wave propagation methods, and advanced signal processing techniques. This paper primarily focuses on the ultrasonic measurement methods and signal processing techniques incorporated into the prototype. High bandwidth ultrasonic transducers combined with an advanced pulse compression technique allowed researchers to 1) obtain high signal-to-noise ratios and 2) obtain accurate and consistent time-of-flight (TOF) measurements through a variety of highly attenuative containers and fluid media. Results of work conducted in the laboratory have demonstrated that the prototype experimental measurement technique also provided information regarding container properties, which will be utilized in future container-independent measurements of hidden liquids.

  11. Prototype instrument for noninvasive ultrasonic inspection and identification of fluids in sealed containers

    NASA Astrophysics Data System (ADS)

    Tucker, Brian J.; Diaz, Aaron A.; Eckenrode, Brian A.

    2006-05-01

    Government agencies and homeland security related organizations have identified the need to develop and establish a wide range of unprecedented capabilities for providing scientific and technical forensic services to investigations involving hazardous chemical, biological, and radiological materials, including extremely dangerous chemical and biological warfare agents. Pacific Northwest National Laboratory (PNNL) has developed a prototype portable, handheld, hazardous materials acoustic inspection prototype that provides noninvasive container interrogation and material identification capabilities using nondestructive ultrasonic velocity and attenuation measurements. Due to the wide variety of fluids as well as container sizes and materials encountered in various law enforcement inspection activities, the need for high measurement sensitivity and advanced ultrasonic measurement techniques were identified. The prototype was developed using a versatile electronics platform, advanced ultrasonic wave propagation methods, and advanced signal processing techniques. This paper primarily focuses on the ultrasonic measurement methods and signal processing techniques incorporated into the prototype. High bandwidth ultrasonic transducers combined with an advanced pulse compression technique allowed researchers to 1) obtain high signal-to-noise ratios and 2) obtain accurate and consistent time-of-flight (TOF) measurements through a variety of highly attenuative containers and fluid media. Results of work conducted in the laboratory have demonstrated that the prototype experimental measurement technique also provided information regarding container properties, which will be utilized in future container-independent measurements of hidden liquids.

  12. Technical management techniques for identification and control of industrial safety and pollution hazards

    NASA Technical Reports Server (NTRS)

    Campbell, R.; Dyer, M. K.; Hoard, E. G.; Little, D. G.; Taylor, A. C.

    1972-01-01

    Constructive recommendations are suggested for pollution problems from offshore energy resources industries on outer continental shelf. Technical management techniques for pollution identification and control offer possible applications to space engineering and management.

  13. AIR PARTICULATE POLLUTION CARDIOVASCULAR TOXICITY: HAZARD IDENTIFICATION AND MECHANISMS OF ACTION

    EPA Science Inventory


    The overall weight of evidence from epidemiological studies has shown statistical associations between air particulate pollution exposure and mortality\\morbidity particularly within individuals with cardiovascular disease (1-4). Identification of causal particle properties ...

  14. In-flight detection and identification and accommodation of aircraft icing

    NASA Astrophysics Data System (ADS)

    Caliskan, Fikret; Hajiyev, Chingiz

    2012-11-01

    The recent improvements and research on aviation have focused on the subject of aircraft safe flight even in the severe weather conditions. As one type of such weather conditions, aircraft icing considerably has negative effects on the aircraft flight performance. The risks of the iced aerodynamic surfaces of the flying aircraft have been known since the beginning of the first flights. Until recent years, as a solution for this event, the icing conditions ahead flight route are estimated from radars or other environmental sensors, hence flight paths are changed, or, if it exists, anti-icing/de-icing systems are used. This work aims at the detection and identification of airframe icing based on statistical properties of aircraft dynamics and reconfigurable control protecting aircraft from hazardous icing conditions. In this paper, aircraft icing identification based on neural networks is investigated. Following icing identification, reconfigurable control is applied for protecting the aircraft from hazardous icing conditions.

  15. Occupational risk identification using hand-held or laptop computers.

    PubMed

    Naumanen, Paula; Savolainen, Heikki; Liesivuori, Jyrki

    2008-01-01

    This paper describes the Work Environment Profile (WEP) program and its use in risk identification by computer. It is installed into a hand-held computer or a laptop to be used in risk identification during work site visits. A 5-category system is used to describe the identified risks in 7 groups, i.e., accidents, biological and physical hazards, ergonomic and psychosocial load, chemicals, and information technology hazards. Each group contains several qualifying factors. These 5 categories are colour-coded at this stage to aid with visualization. Risk identification produces visual summary images the interpretation of which is facilitated by colours. The WEP program is a tool for risk assessment which is easy to learn and to use both by experts and nonprofessionals. It is especially well adapted to be used both in small and in larger enterprises. Considerable time is saved as no paper notes are needed.

  16. Safe procedure development to manage hazardous drugs in the workplace.

    PubMed

    Gaspar Carreño, Marisa; Achau Muñoz, Rubén; Torrico Martín, Fátima; Agún Gonzalez, Juan José; Sanchez Santos, Jose Cristobal; Cercos Lletí, Ana Cristina; Ramos Orozco, Pedro

    2017-03-01

    To develop a safety working procedure for the employees in the Intermutual Hospital de Levante (HIL) in those areas of activity that deal with the handling of hazardous drugs (MP). The procedure was developed in six phases: 1) hazard definition; 2) definition and identification of processes and development of general correct work practices about hazardous drugs' selection and special handling; 3) detection, selection and set of specific recommendations to handle with hazardous drugs during the processes of preparation and administration included in the hospital GFT; 4) categorization of risk during the preparation/administration and development of an identification system; 5) information and training of professionals; 6) implementation of the identification measures and prevention guidelines. Six processes were detected handling HD. During those processes, thirty HD were identified included in the hospital GFT and a safer alternative was found for 6 of them. The HD were classified into 4 risk categories based on those measures to be taken during the preparation and administration of each of them. The development and implementation of specific safety-work processes dealing with medication handling, allows hospital managers to accomplish effectively with their legal obligations about the area of prevention and provides healthcare professional staff with the adequate techniques and safety equipment to avoid possible dangers and risks of some drugs. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  17. Occupational hazards among the abattoir workers associated with noncompliance to the meat processing and waste disposal laws in Malaysia

    PubMed Central

    Abdullahi, Auwalu; Hassan, Azmi; Kadarman, Norizhar; Junaidu, Yakubu Muhammad; Adeyemo, Olanike Kudrat; Lua, Pei Lin

    2016-01-01

    Purpose This study aims to investigate the occupational hazards among the abattoir workers associated with noncompliance to the meat processing and waste disposal laws in Terengganu State, Malaysia. Occupational hazards are the major source of morbidity and mortality among the animal workers due to exposure to many hazardous situations in their daily practices. Occupational infections mostly contracted by abattoir workers could be caused by iatrogenic or transmissible agents, including viruses, bacteria, fungi, and parasites and the toxins produced by these organisms. Materials and methods The methodology was based on a cross-sectional survey using cluster sampling technique in the four districts of Terengganu State, Malaysia. One hundred and twenty-one abattoir workers from five abattoirs were assessed using a validated structured questionnaire and an observation checklist. Results The mean and standard deviation of occupational hazards scores of the workers were 2.32 (2.721). Physical, chemical, biological, psychosocial, musculoskeletal, and ergonomics hazards were the major findings of this study. However, the highest prevalence of occupational hazards identified among the workers was injury by sharp equipment such as a knife (20.0%), noise exposure (17.0%), and due to offensive odor within the abattoir premises (12.0%). Conclusion The major occupational hazards encountered by the workers in the study area were physical, chemical, biological, psychosocial, musculoskeletal, and ergonomics hazards. To ensure proper control of occupational health hazards among the abattoir workers, standard design and good environmental hygiene must be taken into consideration all the time. Exposure control plan, which includes risk identification, risk characterization, assessment of workers at risk, risk control, workers’ education/training, and implementation of safe work procedures, should be implemented by the government and all the existing laws governing the abattoir operation in the country should be enforced. PMID:27471416

  18. Earthquake risk reduction in the United States: An assessment of selected user needs and recommendations for the National Earthquake Hazards Reduction Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1994-12-31

    This Assessment was conducted to improve the National Earthquake Hazards Reduction Program (NEHRP) by providing NEHRP agencies with information that supports their user-oriented setting of crosscutting priorities in the NEHRP strategic planning process. The primary objective of this Assessment was to take a ``snapshot`` evaluation of the needs of selected users throughout the major program elements of NEHRP. Secondary objectives were to conduct an assessment of the knowledge that exists (or is being developed by NEHRP) to support earthquake risk reduction, and to begin a process of evaluating how NEHRP is meeting user needs. An identification of NEHRP`s strengths alsomore » resulted from the effort, since those strengths demonstrate successful methods that may be useful to NEHRP in the future. These strengths are identified in the text, and many of them represent important achievements since the Earthquake Hazards Reduction Act was passed in 1977.« less

  19. 75 FR 57686 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-22

    ... amending the exclusion for the American Steel Cord facility in Scottsburg, Indiana to reflect changes in...- calculated from the delisting health-based levels and a DAF of 68: arsenic-3.4; barium- 100; cadmium-0.34...

  20. HAZARD ASSESSMENT OF METALS AND METAL COMPOUNDS IN TERRESTRIAL SYSTEMS

    EPA Science Inventory

    Metal accumulation in soil can result in adverse effects on soil biota, and may concentrate metals in food chains to levels detrimental to humans and wildlife. A SETAC Pellston Workshop entitled " Hazard Identification Approach For Metals And Inorganic Metal Substances" examined...

  1. 40 CFR 261.30 - General.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Corrosive Waste (C) Reactive Waste (R) Toxicity Characteristic Waste (E) Acute Hazardous Waste (H) Toxic... Toxicity Characteristic Waste (E) or Toxic Waste (T) in §§ 261.31 and 261.32. (c) Each hazardous waste... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION...

  2. 40 CFR 261.30 - General.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) Corrosive Waste (C) Reactive Waste (R) Toxicity Characteristic Waste (E) Acute Hazardous Waste (H) Toxic... Toxicity Characteristic Waste (E) or Toxic Waste (T) in §§ 261.31 and 261.32. (c) Each hazardous waste... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION...

  3. 40 CFR 261.30 - General.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) Corrosive Waste (C) Reactive Waste (R) Toxicity Characteristic Waste (E) Acute Hazardous Waste (H) Toxic... Toxicity Characteristic Waste (E) or Toxic Waste (T) in §§ 261.31 and 261.32. (c) Each hazardous waste... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION...

  4. 40 CFR 261.30 - General.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) Corrosive Waste (C) Reactive Waste (R) Toxicity Characteristic Waste (E) Acute Hazardous Waste (H) Toxic... Toxicity Characteristic Waste (E) or Toxic Waste (T) in §§ 261.31 and 261.32. (c) Each hazardous waste... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION...

  5. 40 CFR 261.30 - General.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) Corrosive Waste (C) Reactive Waste (R) Toxicity Characteristic Waste (E) Acute Hazardous Waste (H) Toxic... Toxicity Characteristic Waste (E) or Toxic Waste (T) in §§ 261.31 and 261.32. (c) Each hazardous waste... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION...

  6. The LLNA: A Brief Review of Recent Advances and Limitations

    PubMed Central

    Anderson, Stacey E.; Siegel, Paul D.; Meade, B. J.

    2011-01-01

    Allergic contact dermatitis is the second most commonly reported occupational illness, accounting for 10% to 15% of all occupational diseases. This highlights the importance of developing rapid and sensitive methods for hazard identification of chemical sensitizers. The murine local lymph node assay (LLNA) was developed and validated for the identification of low molecular weight sensitizing chemicals. It provides several benefits over other tests for sensitization because it provides a quantitative endpoint, dose-responsive data, and allows for prediction of potency. However, there are also several concerns with this assay including: levels of false positive responses, variability due to vehicle, and predictivity. This report serves as a concise review which briefly summarizes the progress, advances and limitations of the assay over the last decade. PMID:21747867

  7. Insurance companies' point of view toward moral hazard incentives.

    PubMed

    Khorasani, Elahe; Keyvanara, Mahmoud; Etemadi, Manal; Asadi, Somayeh; Mohammadi, Mahan; Barati, Maryam

    2016-01-01

    Moral hazards are the result of an expansive range of factors mostly originating in the patients' roles. The objective of the present study was to investigate patient incentives for moral hazards using the experiences of experts of basic Iranian insurance organizations. This was a qualitative research. Data were collected through semi-structured interviews. The study population included all experts of basic healthcare insurance agencies in the City of Isfahan, Iran, who were familiar with the topic of moral hazards. A total of 18 individuals were selected through purposive sampling and interviewed and some criteria such as data reliability and stability were considered. The anonymity of the interviewees was preserved. The data were transcribed, categorized, and then, analyzed through thematic analysis method. Through thematic analysis, 2 main themes and 11 subthemes were extracted. The main themes included economic causes and moral-cultural causes affecting the phenomenon of moral hazards resulted from patients' roles. Each of these themes has some sub-themes. False expectations from insurance companies are rooted in the moral and cultural values of individuals. People with the insurance coverage make no sense if using another person insurance identification or requesting physicians for prescribing the medicines. These expectations will lead them to moral hazards. Individuals with any insurance coverage should consider the rights of insurance agencies as third party payers and supportive organizations which disburden them from economical loads in the time of sickness.

  8. ERTS-1 imagery and high flight photographs as aids to fire hazard appraisal at the NASA San Pablo Reservoir test site

    NASA Technical Reports Server (NTRS)

    Colwell, R. N.

    1973-01-01

    The identification of fire hazards at the San Pablo Reservoir Test Site in California using ERTS-1 data is discussed. It is stated that the two primary fire hazards in the area are caused by wild oat plants and eucalyptus trees. The types of imagery used in conducting the study are reported. Aerial photographs of specific areas are included to show the extent of the fire hazards.

  9. GRC Payload Hazard Assessment: Supporting the STS-107 Accident Investigation

    NASA Technical Reports Server (NTRS)

    Schoren, William R.; Zampino, Edward J.

    2004-01-01

    A hazard assessment was conducted on the GRC managed payloads in support of a NASA Headquarters Code Q request to examine STS-107 payloads and determine if they were credible contributors to the Columbia accident. This assessment utilized each payload's Final Flight Safety Data Package for hazard identification. An applicability assessment was performed and most of the hazards were eliminated because they dealt with payload operations or crew interactions. A Fault Tree was developed for all the hazards deemed applicable and the safety verification documentation was reviewed for these applicable hazards. At the completion of this hazard assessment, it was concluded that none of the GRC managed payloads were credible contributors to the Columbia accident.

  10. Research and Evaluations of the Health Aspects of Disasters, Part IX: Risk-Reduction Framework.

    PubMed

    Birnbaum, Marvin L; Daily, Elaine K; O'Rourke, Ann P; Loretti, Alessandro

    2016-06-01

    A disaster is a failure of resilience to an event. Mitigating the risks that a hazard will progress into a destructive event, or increasing the resilience of a society-at-risk, requires careful analysis, planning, and execution. The Disaster Logic Model (DLM) is used to define the value (effects, costs, and outcome(s)), impacts, and benefits of interventions directed at risk reduction. A Risk-Reduction Framework, based on the DLM, details the processes involved in hazard mitigation and/or capacity-building interventions to augment the resilience of a community or to decrease the risk that a secondary event will develop. This Framework provides the structure to systematically undertake and evaluate risk-reduction interventions. It applies to all interventions aimed at hazard mitigation and/or increasing the absorbing, buffering, or response capacities of a community-at-risk for a primary or secondary event that could result in a disaster. The Framework utilizes the structure provided by the DLM and consists of 14 steps: (1) hazards and risks identification; (2) historical perspectives and predictions; (3) selection of hazard(s) to address; (4) selection of appropriate indicators; (5) identification of current resilience standards and benchmarks; (6) assessment of the current resilience status; (7) identification of resilience needs; (8) strategic planning; (9) selection of an appropriate intervention; (10) operational planning; (11) implementation; (12) assessments of outputs; (13) synthesis; and (14) feedback. Each of these steps is a transformation process that is described in detail. Emphasis is placed on the role of Coordination and Control during planning, implementation of risk-reduction/capacity building interventions, and evaluation. Birnbaum ML , Daily EK , O'Rourke AP , Loretti A . Research and evaluations of the health aspects of disasters, part IX: Risk-Reduction Framework. Prehosp Disaster Med. 2016;31(3):309-325.

  11. Using human factors engineering to improve patient safety in the cardiovascular operating room.

    PubMed

    Gurses, Ayse P; Martinez, Elizabeth A; Bauer, Laura; Kim, George; Lubomski, Lisa H; Marsteller, Jill A; Pennathur, Priyadarshini R; Goeschel, Chris; Pronovost, Peter J; Thompson, David

    2012-01-01

    Despite significant medical advances, cardiac surgery remains a high risk procedure. Sub-optimal work system design characteristics can contribute to the risks associated with cardiac surgery. However, hazards due to work system characteristics have not been identified in the cardiovascular operating room (CVOR) in sufficient detail to guide improvement efforts. The purpose of this study was to identify and categorize hazards (anything that has the potential to cause a preventable adverse patient safety event) in the CVOR. An interdisciplinary research team used prospective hazard identification methods including direct observations, contextual inquiry, and photographing to collect data in 5 hospitals for a total 22 cardiac surgeries. We performed thematic analysis of the qualitative data guided by a work system model. 60 categories of hazards such as practice variations, high workload, non-compliance with evidence-based guidelines, not including clinicians' in medical device purchasing decisions were found. Results indicated that hazards are common in cardiac surgery and should be eliminated or mitigated to improve patient safety. To improve patient safety in the CVOR, efforts should focus on creating a culture of safety, increasing compliance with evidence based infection control practices, improving communication and teamwork, and designing better tools and technologies through partnership among all stakeholders.

  12. HAZARDOUS WASTE IDENTIFICATION

    EPA Science Inventory

    This research is in direct support of the regulatory reform efforts under the Hazarous Waste Identification (HWIR) and is related to the development of national "exit levels" based on sound scientific data and models. Research focuses on developing a systems approach to modelin...

  13. Effect of systematic ergonomic hazard identification and control implementation on musculoskeletal disorder and injury risk

    PubMed Central

    Cantley, Linda F; Taiwo, Oyebode A; Galusha, Deron; Barbour, Russell; Slade, Martin D; Tessier-Sherman, Baylah; Cullen, Mark R

    2014-01-01

    Objectives This study aimed to examine the effect of an ergonomic hazard control (HC) initiative, undertaken as part of a company ergonomics standard, on worker injury risk. Methods Using the company's ergonomic hazards database to identify jobs with and without ergonomic HC implementation and linking to individual job and injury histories, injury risk among person-jobs with HC implementation (the HC group) was compared to those without HC (NoHC group) using random coefficient models. Further analysis of the HC group was conducted to determine the effect of additional ergonomic hazards controlled on injury risk. Results Among 123jobs at 17 plant locations, 347 ergonomic hazards were quantitatively identified during the study period. HC were implemented for 204 quantified ergonomic hazards in 84 jobs, impacting 10 385 persons (12 967 person-jobs). No HC were implemented for quantified ergonomic hazards in the remaining 39 jobs affecting 4155 persons (5046 person-jobs). Adjusting for age, sex, plant origin, and year to control for any temporal trend in injury risk, the relative risk (RR) for musculoskeletal disorder (MSD) was 0.85 and the RR for any injury or MSD was 0.92 in the HC compared to NoHC group. Among the HC group, each ergonomic hazard controlled was associated with risk reduction for MSD and acute injury outcomes (RR 0.93). Conclusion Systematic ergonomic HC through participatory ergonomics, as part of a mandatory company ergonomics standard, is associated with MSD and injury risk reduction among workers in jobs with HC implemented. PMID:24142048

  14. Hazardous Waste Management System - Identification and Listing of Hazardous Waste - Recycled Used Oil Management Standards - Federal Register Notice, May 3, 1993

    EPA Pesticide Factsheets

    This action corrects several technical errors and provides clarifying amendments to the final recycled used oil management standards rule. The final rule was published on September 10, 1992 (57 FR 41566).

  15. Hazardous Waste Management System - Identification and Listing of Hazardous Waste - Toxicity Characteristic - Hydrocarbon Recovery Operations - Federal Register Notice, February 1, 1991

    EPA Pesticide Factsheets

    Extends the compliance date of the Toxicity Characteristic until January 25, 1991 for groundwater that is reinjected or reinfiltrated during existing hydrocarbon recovery operations at petroleum refineries, marketing terminals, and bulk plants.

  16. 49 CFR 178.44 - Specification 3HT seamless steel cylinders for aircraft use.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... to check analysis for phosphorus. (c) Identification of material. Material must be identified by any... aircraft use. 178.44 Section 178.44 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS...

  17. 40 CFR 272.751 - Indiana state-administered program: Final authorization.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    .... Hazardous Waste Management System; Testing and Monitoring Activities (Checklist 158) 62 FR 32452 June 13... Management System; Carbamate Production, Identification and Listing of Hazardous Waste; Land Disposal... Indiana Department of Environmental Management, signed by the Commissioner of the IDEM on February 14...

  18. APPLICATION OF EXAMS AS THE SURFACE WATER MODULE IN THE HWIR MULTIMEDIA RISK ASSESSMENT SYSTEM

    EPA Science Inventory

    Multimedia, multipathway risk assessment software has been developed for implementing the Hazardous Waste Identification Rule (HWIR). This regulation is intended to determine whether a waste should be considered hazardous, and confined to Subtitle D facilities, or safely release...

  19. Quantitative meta-analytic approaches for the analysis of animal toxicology and epidemiologic data in human health risk assessments

    EPA Science Inventory

    Often, human health risk assessments have relied on qualitative approaches for hazard identification to integrate evidence across multiple studies to conclude whether particular hazards exist. However, quantitative approaches for evidence integration, including the application o...

  20. Installation-restoration program. Preliminary assessment: 201st Red Horse, Civil Engineering Flight, Fort Indiantown Gap Air National Guard Station, Pennsylvania Air National Guard, Annville, Pennsylvania

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1991-02-01

    The preliminary assessment included the following activities: (1) An on-site visit, including interviews and field surveys; (2) Acquisition and analysis of information on past hazardous materials use, waste generation, and waste disposal at the Station; (3) Acquisition and analysis of available geological surveys, hydrological data, meteorological data, and environmental data; and (4) The identification and assessment of sites where contamination of soils, ground water and/or surface water may have occurred. Operations that have involved the use of hazardous materials and the disposal of hazardous wastes include vehicle maintenance and aerospace ground equipment (AGE) maintenance. The hazardous wastes disposed of throughmore » these operations include varying quantities of petroleum-oil-lubricant (POL) products, acids, paints, thinners, strippers, and solvents. The field surveys and interviews resulted in the identification of three sites that exhibit the potential for migration of contaminants due to leakage or seepage from landfills and storage tanks.« less

  1. A simple tool for preliminary hazard identification and quick assessment in craftwork and small/medium enterprises (SME).

    PubMed

    Colombini, Daniela; Occhipinti, E; Di Leone, G

    2012-01-01

    During the last Congress of the International Ergonomics Association (IEA), Beijing, August 2009, an international group was founded aimed at developing a "toolkit for MSD prevention" within IEA and in collaboration with World Health Organization (WHO). Possible users of toolkits are: members of health and safety committees, health and safety representatives, line supervisors; labor inspectors; health workers implementing basic occupational health services; occupational health and safety specialists.According to ISO standard 11228 series and the new Draft CD ISO 12259-2009: Application document guides for the potential user, a computer software ( in Excel®) was create dealing with hazard "mapping" in handicraft The proposed methodology, using specific key enters and quick assessment criteria, allows a simple ergonomics hazard identification and risk estimation. Thus it makes possible to decide for which professional hazards a more exhaustive risk assessment will be necessary and which professional consultant should be involved (occupational physician, safety engineer, industrial hygienist, etc.).

  2. Safety assessment of plant varieties using transcriptomics profiling and a one-class classifier.

    PubMed

    van Dijk, Jeroen P; de Mello, Carla Souza; Voorhuijzen, Marleen M; Hutten, Ronald C B; Arisi, Ana Carolina Maisonnave; Jansen, Jeroen J; Buydens, Lutgarde M C; van der Voet, Hilko; Kok, Esther J

    2014-10-01

    An important part of the current hazard identification of novel plant varieties is comparative targeted analysis of the novel and reference varieties. Comparative analysis will become much more informative with unbiased analytical approaches, e.g. omics profiling. Data analysis estimating the similarity of new varieties to a reference baseline class of known safe varieties would subsequently greatly facilitate hazard identification. Further biological and eventually toxicological analysis would then only be necessary for varieties that fall outside this reference class. For this purpose, a one-class classifier tool was explored to assess and classify transcriptome profiles of potato (Solanum tuberosum) varieties in a model study. Profiles of six different varieties, two locations of growth, two year of harvest and including biological and technical replication were used to build the model. Two scenarios were applied representing evaluation of a 'different' variety and a 'similar' variety. Within the model higher class distances resulted for the 'different' test set compared with the 'similar' test set. The present study may contribute to a more global hazard identification of novel plant varieties. Copyright © 2014 Elsevier Inc. All rights reserved.

  3. The local lymph node assay in 2014.

    PubMed

    Basketter, David A; Gerberick, G Frank; Kimber, Ian

    2014-01-01

    Toxicology endeavors to predict the potential of materials to cause adverse health (and environmental) effects and to assess the risk(s) associated with exposure. For skin sensitizers, the local lymph node assay was the first method to be fully and independently validated, as well as the first to offer an objective end point with a quantitative measure of sensitizing potency (in addition to hazard identification). Fifteen years later, it serves as the primary standard for the development of in vitro/in chemico/in silico alternatives.

  4. Identification of potentially hazardous human gene products in GMO risk assessment.

    PubMed

    Bergmans, Hans; Logie, Colin; Van Maanen, Kees; Hermsen, Harm; Meredyth, Michelle; Van Der Vlugt, Cécile

    2008-01-01

    Genetically modified organisms (GMOs), e.g. viral vectors, could threaten the environment if by their release they spread hazardous gene products. Even in contained use, to prevent adverse consequences, viral vectors carrying genes from mammals or humans should be especially scrutinized as to whether gene products that they synthesize could be hazardous in their new context. Examples of such potentially hazardous gene products (PHGPs) are: protein toxins, products of dominant alleles that have a role in hereditary diseases, gene products and sequences involved in genome rearrangements, gene products involved in immunomodulation or with an endocrine function, gene products involved in apoptosis, activated proto-oncogenes. For contained use of a GMO that carries a construct encoding a PHGP, the precautionary principle dictates that safety measures should be applied on a "worst case" basis, until the risks of the specific case have been assessed. The potential hazard of cloned genes can be estimated before empirical data on the actual GMO become available. Preliminary data may be used to focus hazard identification and risk assessment. Both predictive and empirical data may also help to identify what further information is needed to assess the risk of the GMO. A two-step approach, whereby a PHGP is evaluated for its conceptual dangers, then checked by data bank searches, is delineated here.

  5. Portable total reflection x-ray fluorescence analysis in the identification of unknown laboratory hazards

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Ying, E-mail: liu.ying.48r@st.kyoto-u.ac.jp; Imashuku, Susumu; Sasaki, Nobuharu

    In this study, a portable total reflection x-ray fluorescence (TXRF) spectrometer was used to analyze unknown laboratory hazards that precipitated on exterior surfaces of cooling pipes and fume hood pipes in chemical laboratories. With the aim to examine the accuracy of TXRF analysis for the determination of elemental composition, analytical results were compared with those of wavelength-dispersive x-ray fluorescence spectrometry, scanning electron microscope and energy-dispersive x-ray spectrometry, energy-dispersive x-ray fluorescence spectrometry, inductively coupled plasma atomic emission spectrometry, x-ray diffraction spectrometry (XRD), and x-ray photoelectron spectroscopy (XPS). Detailed comparison of data confirmed that the TXRF method itself was not sufficient tomore » determine all the elements (Z > 11) contained in the samples. In addition, results suggest that XRD should be combined with XPS in order to accurately determine compound composition. This study demonstrates that at least two analytical methods should be used in order to analyze the composition of unknown real samples.« less

  6. Geoelectrical Tomography for landslide monitoring: state-of-the-art and future challenges.

    NASA Astrophysics Data System (ADS)

    Lapenna, V.; Perrone, A.; Piscitelli, S.

    2011-12-01

    Recently, novel algorithms for tomographic data inversion, robust models for describing the hydrogeophysical processes and new sensor networks for the field data acquisition have rapidly transformed the geoelectrical methods in a powerful and cost-effective tool for geo-hazard monitoring. These technological and methodological improvements disclose the way for a wide spectra of interesting and challenging applications in geo-hazards monitoring: reconstruction of landslide geometry; identification of fluid and gas uprising in volcanic areas; electrical imaging of seismic faults etc.. We briefly resume the current state-of-the-art of the geoelectrical methods in landslide monitoring and introduce new and emerging applications of the geoelectrical tomographic methods. An overview of the more interesting results obtained in different areas of Italian territory affected by wide and diffuse hydrogeological instability phenomena will be presented and discussed. We will focus the attention to some recent results obtained in the frame of national and international projects (Morfeo, Eurorisk/Preview, DORIS). One of the key challenges for the future will be the integration of active (Resistivity) and passive (Self-Potential) measurements for obtaining 2D, 3D and 4D (time-lapse) electrical tomographies able to follow the spatial and temporal dynamics of electrical parameters (i.e. resistivity, self-potential) inside the landslide body. The resistivity imaging can be applied for illuminating the sliding surfaces and for mapping the time-dependent changes of water content in vadose zones, while the Self Potential imaging could give a significant contribute for delineating the groundwater circulation patterns and to the early identification of triggering factors.

  7. 75 FR 20942 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Removal of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-22

    ... of the waste generation and management information for saccharin and its salts, which demonstrate... partnership with the States, biennially collects information regarding the generation, management, and final... Based on the Available Toxicological Information and Waste Generation and Management Information for...

  8. Hazardous Waste Management System - Identification and Listing of Hazardous Waste - Toxicity Characteristic - Hydrocarbon Recovery Operations - Federal Register Notice, April 2, 1991

    EPA Pesticide Factsheets

    Proposal to extend the compliance date for the Toxicity Characteristic until January 25, 1993 for produced groundwater from free phase hydrocarbon recovery operations at certain petroleum industry sites-namely, refineries, marketing terminals, bulk plants.

  9. Risk and Risk Assessment in Environmental Education.

    ERIC Educational Resources Information Center

    Chiras, Daniel D.

    1982-01-01

    Risk assessment (the identification of hazards, the determination of the probability of a hazardous event occurring, and an estimation of the severity of such an event's occurrence) is suggested as a technique to be used to analyze current issues in environmental education in an objective manner. (PEB)

  10. 75 FR 32682 - National Emission Standards for Hazardous Air Pollutants for Major Sources: Industrial...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... for Existing Sources: Commercial and Industrial Solid Waste Incineration Units; Identification of Non-Hazardous Secondary Materials That Are Solid Waste AGENCY: Environmental Protection Agency. ACTION: Notice... Institutional Boilers located at area sources; and Commercial and Industrial Solid Waste Incineration Units. On...

  11. SETAC Pellston WorkshopTM: Environmental hazard and risk assessment approaches for endocrine-active chemicals (EHRA)

    EPA Science Inventory

    Suspected endocrine disrupting substances (EDS) are now being evaluated by several regulatory authorities. A debate is in progress about whether or not EDS can be adequately assessed by following the standard approach involving identification of intrinsic hazards, prediction of e...

  12. Comparison of Methane Control Methods in Polish and Vietnamese Coal Mines

    NASA Astrophysics Data System (ADS)

    Borowski, Marek; Kuczera, Zbigniew

    2018-03-01

    Methane hazard often occurs in hard coal mines and causes very serious accidents and can be the reason of methane or methane and coal dust explosions. History of coal mining shows that methane released from the rock mass to the longwall area was responsible for numerous mining disasters. The main source of methane are coal deposits because it is autochthonous gas and is closely related with carbonification and forming of coal deposits. Degree of methane saturation in coal deposits depends on numerous factors; mainly on presence or lack of insulating layers in cover deposit that allow or do not on degasification and easily methane outflow into surroundings. Hence in coal mining there are coal deposits that contain only low degree of methane saturation in places where is lack of insulating layers till high in methane coal deposits occurring in insulating claystones or in shales. Conducting mining works in coal deposits of high methane hazard without using of special measures to combat (ventilation, methane drainage) could be impossible. Control of methane hazard depends also on other co-occuring natural dangers for which used preventive actions eliminate methane hazard. Safety in mines excavating coal deposits saturated with methane depends on the correct estimation of methane hazard, drawn up forecasts, conducted observations, hazard control as well as undertaken prevention measures. Methane risk prevention includes identification and control methods of methane hazards as well as means of combating the explosive accumulation of methane in longwall workings. The main preventive actions in underground coal mines are: effective ventilation that prevents forming of methane fuses or placed methane accumulation in headings ventilated by airflow created by main fans and in headings with auxiliary ventilation, methane drainage using drain holes that are drilled from underground headings or from the surface, methanometry control of methane concentration in the air; location of the sensors is defined by law, additional ventilation equipment used in places of lower intensity of ventilation and places where methane is concentrated.

  13. Systematic risk assessment methodology for critical infrastructure elements - Oil and Gas subsectors

    NASA Astrophysics Data System (ADS)

    Gheorghiu, A.-D.; Ozunu, A.

    2012-04-01

    The concern for the protection of critical infrastructure has been rapidly growing in the last few years in Europe. The level of knowledge and preparedness in this field is beginning to develop in a lawfully organized manner, for the identification and designation of critical infrastructure elements of national and European interest. Oil and gas production, refining, treatment, storage and transmission by pipelines facilities, are considered European critical infrastructure sectors, as per Annex I of the Council Directive 2008/114/EC of 8 December 2008 on the identification and designation of European critical infrastructures and the assessment of the need to improve their protection. Besides identifying European and national critical infrastructure elements, member states also need to perform a risk analysis for these infrastructure items, as stated in Annex II of the above mentioned Directive. In the field of risk assessment, there are a series of acknowledged and successfully used methods in the world, but not all hazard identification and assessment methods and techniques are suitable for a given site, situation, or type of hazard. As Theoharidou, M. et al. noted (Theoharidou, M., P. Kotzanikolaou, and D. Gritzalis 2009. Risk-Based Criticality Analysis. In Critical Infrastructure Protection III. Proceedings. Third Annual IFIP WG 11.10 International Conference on Critical Infrastructure Protection. Hanover, New Hampshire, USA, March 23-25, 2009: revised selected papers, edited by C. Palmer and S. Shenoi, 35-49. Berlin: Springer.), despite the wealth of knowledge already created, there is a need for simple, feasible, and standardized criticality analyses. The proposed systematic risk assessment methodology includes three basic steps: the first step (preliminary analysis) includes the identification of hazards (including possible natural hazards) for each installation/section within a given site, followed by a criterial analysis and then a detailed analysis step. The criterial evaluation is used as a ranking system in order to establish the priorities for the detailed risk assessment. This criterial analysis stage is necessary because the total number of installations and sections on a site can be quite large. As not all installations and sections on a site contribute significantly to the risk of a major accident occurring, it is not efficient to include all installations and sections in the detailed risk assessment, which can be time and resource consuming. The selected installations are then taken into consideration in the detailed risk assessment, which is the third step of the systematic risk assessment methodology. Following this step, conclusions can be drawn related to the overall risk characteristics of the site. The proposed methodology can as such be successfully applied to the assessment of risk related to critical infrastructure elements falling under the energy sector of Critical Infrastructure, mainly the sub-sectors oil and gas. Key words: Systematic risk assessment, criterial analysis, energy sector critical infrastructure elements

  14. Portable medical status system. [potential hazards in the use of the telecare system

    NASA Technical Reports Server (NTRS)

    Lindsey, O. C.

    1976-01-01

    The hazards inherent in the Portable Medical Status System are identified, and the measures taken to reduce them to an acceptable level are described. Identification of these hazards is a prerequisite to use of the system on humans in the earth environment. One hazard which is insufficiently controlled and which is considered a constraint to use on humans is the level of current possible in the electrodes for the EEG (electroencephalograph) circuitry. It exceeds the maximum specified. A number of procedural and design recommendations for enhancement of safety are made.

  15. Skin sensitization in chemical risk assessment: Report of aWHO/IPCS international workshop focusing on dose–responseassessment

    EPA Science Inventory

    An international workshop was held in 2006 to evaluate experimental techniques for hazard identification and hazard characterization of sensitizing agents in terms of their ability to produce data, including dose–response information, to inform risk assessment. Human testing to i...

  16. 75 FR 62040 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Proposed Exclusion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-07

    ... on- site in the pickle acid and low level radioactive wastewater treatment systems. Support... water production waste treatment system. Once- through non-contact cooling water does not require... production (deionized and make- up non-contact cooling water) treatment system and once through non- contact...

  17. 75 FR 78918 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Removal of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... management information for saccharin and its salts. This review/assessment demonstrates that saccharin and... Generation and Management Information for Saccharin and Its Salts A. Evaluation of Toxicological Information... generation and management information for saccharin and its salts. This review/assessment demonstrates that...

  18. 40 CFR 261.151 - Wording of the instruments.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 27 2012-07-01 2012-07-01 false Wording of the instruments. 261.151 Section 261.151 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Financial Requirements for Management of Excluded Hazardous Secondary Materials § 261.151...

  19. 40 CFR 261.151 - Wording of the instruments.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Wording of the instruments. 261.151 Section 261.151 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Financial Requirements for Management of Excluded Hazardous Secondary Materials § 261.151...

  20. Hazardous Waste Management System - Identification and Listing of Hazardous Waste - Toxicity Characteristic - Hydrocarbon Recovery Operations - Federal Register Notice, October 5, 1990

    EPA Pesticide Factsheets

    The Agency is promulgating an interim final rule to extend the compliance date of the Toxicity Characteristic rule for petroleum refining facilities, marketing terminals and bulk plants engaged in the recovery and remediation operation for 120 days.

  1. Hazardous Waste Management System - General - Identification and Listing of Hazardous Waste - Used Oil - Federal Register Notice, May 20, 1992

    EPA Pesticide Factsheets

    EPA is today promulgating a final listing decision for used oils based upon the technical criteria provided in the Resource Conservation and Recovery Act (RCRA) sections 1004 and 3001 and in 40 CFR 261.11 (a)(1) and (a)(3).

  2. 49 CFR 178.59 - Specification 8 steel cylinders with porous fillings for acetylene.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS...: Carbon, 0.25; phosphorus, 0.045; sulphur, 0.050. (c) Identification of steel. Materials must be... bottoms closed in by spinning must be subjected to a leakage test by setting the interior air or gas...

  3. 44 CFR 201.4 - Standard State Mitigation Plans.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... resources to reducing the effects of natural hazards. (b) Planning process. An effective planning process is... mitigation as well as to development in hazard-prone areas; a discussion of State funding capabilities for... identified. (iv) Identification of current and potential sources of Federal, State, local, or private funding...

  4. 44 CFR 201.4 - Standard State Mitigation Plans.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... resources to reducing the effects of natural hazards. (b) Planning process. An effective planning process is... mitigation as well as to development in hazard-prone areas; a discussion of State funding capabilities for... identified. (iv) Identification of current and potential sources of Federal, State, local, or private funding...

  5. 29 CFR 1910.144 - Safety color code for marking physical hazards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the basic color for the identification of: (i) Fire protection equipment and apparatus. [Reserved] (ii... 29 Labor 5 2011-07-01 2011-07-01 false Safety color code for marking physical hazards. 1910.144 Section 1910.144 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH...

  6. Simulating Geriatric Home Safety Assessments in a Three-Dimensional Virtual World

    ERIC Educational Resources Information Center

    Andrade, Allen D.; Cifuentes, Pedro; Mintzer, Michael J.; Roos, Bernard A.; Anam, Ramanakumar; Ruiz, Jorge G.

    2012-01-01

    Virtual worlds could offer inexpensive and safe three-dimensional environments in which medical trainees can learn to identify home safety hazards. Our aim was to evaluate the feasibility, usability, and acceptability of virtual worlds for geriatric home safety assessments and to correlate performance efficiency in hazard identification with…

  7. A proposal for a test method for assessment of hazard property HP 12 ("Release of an acute toxic gas") in hazardous waste classification - Experience from 49 waste.

    PubMed

    Hennebert, Pierre; Samaali, Ismahen; Molina, Pauline

    2016-12-01

    A stepwise method for assessment of the HP 12 is proposed and tested with 49 waste samples. The hazard property HP 12 is defined as "Release of an acute toxic gas": waste which releases acute toxic gases (Acute Tox. 1, 2 or 3) in contact with water or an acid. When a waste contains a substance assigned to one of the following supplemental hazards EUH029, EUH031 and EUH032, it shall be classified as hazardous by HP 12 according to test methods or guidelines (EC, 2014a, 2014b). When the substances with the cited hazard statement codes react with water or an acid, they can release HCl, Cl 2 , HF, HCN, PH 3 , H 2 S, SO 2 (and two other gases very unlikely to be emitted, hydrazoic acid HN 3 and selenium oxide SeO 2 - a solid with low vapor pressure). Hence, a method is proposed:For a set of 49 waste, water addition did not produce gas. Nearly all the solid waste produced a gas in contact with hydrochloric acid in 5 min in an automated calcimeter with a volume >0.1L of gas per kg of waste. Since a plateau of pressure is reached only for half of the samples in 5 min, 6 h trial with calorimetric bombs or glass flasks were done and confirmed the results. Identification of the gases by portable probes showed that most of the tested samples emit mainly CO 2 . Toxic gases are emitted by four waste: metallic dust from the aluminum industry (CO), two air pollution control residue of industrial waste incinerator (H 2 S) and a halogenated solvent (organic volatile(s) compound(s)). HF has not been measured in these trials started before the present definition of HP 12. According to the definition of HP 12, only the H 2 S emission of substances with hazard statement EUH031 is accounted for. In view of the calcium content of the two air pollution control residue, the presence of calcium sulphide (EUH031) can be assumed. These two waste are therefore classified potentially hazardous for HP 12, from a total of 49 waste. They are also classified as hazardous for other properties (HP 7, 10and14 for one of them, and HP 10and14 for the other one respectively). Given these results, it can be assumed that few common household and industrial waste will be classified hazardous only by HP 12. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Biokinetically-Based In Vitro Cardiotoxicity of Residual Oil Fly Ash: Hazard Identification and Mechanisms of Injury

    EPA Science Inventory

    Epidemiological studies have associated air pollution particulate matter (PM) exposure with adverse cardiovascular effects. Identification of causal PM sources is critically needed to support regulatory decisions to protect public health. This research examines the in vitro car...

  9. PINS Spectrum Identification Guide

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    A.J. Caffrey

    2012-03-01

    The Portable Isotopic Neutron Spectroscopy—PINS, for short—system identifies the chemicals inside munitions and containers without opening them, a decided safety advantage if the fill chemical is a hazardous substance like a chemical warfare agent or an explosive. The PINS Spectrum Identification Guide is intended as a reference for technical professionals responsible for the interpretation of PINS gamma-ray spectra. The guide is divided into two parts. The three chapters that constitute Part I cover the science and technology of PINS. Neutron activation analysis is the focus of Chapter 1. Chapter 2 explores PINS hardware, software, and related operational issues. Gamma-ray spectralmore » analysis basics are introduced in Chapter 3. The six chapters of Part II cover the identification of PINS spectra in detail. Like the PINS decision tree logic, these chapters are organized by chemical element: phosphorus-based chemicals, chlorine-based chemicals, etc. These descriptions of hazardous, toxic, and/or explosive chemicals conclude with a chapter on the identification of the inert chemicals, e.g. sand, used to fill practice munitions.« less

  10. Geotechnical applications of LiDAR pertaining to geomechanical evaluation and hazard identification

    NASA Astrophysics Data System (ADS)

    Lato, Matthew J.

    Natural hazards related to ground movement that directly affect the safety of motorists and highway infrastructure include, but are not limited to, rockfalls, rockslides, debris flows, and landslides. This thesis specifically deals with the evaluation of rockfall hazards through the evaluation of LiDAR data. Light Detection And Ranging (LiDAR) is an imaging technology that can be used to delineate and evaluate geomechanically-controlled hazards. LiDAR has been adopted to conduct hazard evaluations pertaining to rockfall, rock-avalanches, debris flows, and landslides. Characteristics of LiDAR surveying, such as rapid data acquisition rates, mobile data collection, and high data densities, pose problems to traditional CAD or GIS-based mapping methods. New analyses methods, including tools specifically oriented to geomechanical analyses, are needed. The research completed in this thesis supports development of new methods, including improved survey techniques, innovative software workflows, and processing algorithms to aid in the detection and evaluation of geomechanically controlled rockfall hazards. The scientific research conducted between the years of 2006-2010, as presented in this thesis, are divided into five chapters, each of which has been published by or is under review by an international journal. The five research foci are: (i) geomechanical feature extraction and analysis using LiDAR data in active mining environments; (ii) engineered monitoring of rockfall hazards along transportation corridors: using mobile terrestrial LiDAR; (iii) optimization of LiDAR scanning and processing for automated structural evaluation of discontinuities in rockmasses; (iv) location orientation bias when using static LiDAR data for geomechanical analysis; and (v) evaluating roadside rockmasses for rockfall hazards from LiDAR data: optimizing data collection and processing protocols. The research conducted pertaining to this thesis has direct and significant implications with respect to numerous engineering projects that are affected by geomechanical stability issues. The ability to efficiently and accurately map discontinuities, detect changes, and standardize roadside geomechanical stability analyses from remote locations will fundamentally change the state-of-practice of geotechnical investigation workflows and repeatable monitoring. This, in turn, will lead to earlier detection and definition of potential zones of instability, will allow for progressive monitoring and risk analysis, and will indicate the need for pro-active slope improvement and stabilization.

  11. Integrative Chemical-Biological Read-Across Approach for Chemical Hazard Classification

    PubMed Central

    Low, Yen; Sedykh, Alexander; Fourches, Denis; Golbraikh, Alexander; Whelan, Maurice; Rusyn, Ivan; Tropsha, Alexander

    2013-01-01

    Traditional read-across approaches typically rely on the chemical similarity principle to predict chemical toxicity; however, the accuracy of such predictions is often inadequate due to the underlying complex mechanisms of toxicity. Here we report on the development of a hazard classification and visualization method that draws upon both chemical structural similarity and comparisons of biological responses to chemicals measured in multiple short-term assays (”biological” similarity). The Chemical-Biological Read-Across (CBRA) approach infers each compound's toxicity from those of both chemical and biological analogs whose similarities are determined by the Tanimoto coefficient. Classification accuracy of CBRA was compared to that of classical RA and other methods using chemical descriptors alone, or in combination with biological data. Different types of adverse effects (hepatotoxicity, hepatocarcinogenicity, mutagenicity, and acute lethality) were classified using several biological data types (gene expression profiling and cytotoxicity screening). CBRA-based hazard classification exhibited consistently high external classification accuracy and applicability to diverse chemicals. Transparency of the CBRA approach is aided by the use of radial plots that show the relative contribution of analogous chemical and biological neighbors. Identification of both chemical and biological features that give rise to the high accuracy of CBRA-based toxicity prediction facilitates mechanistic interpretation of the models. PMID:23848138

  12. Evaluation of a Parchment Document, the 13th Century Incorporation Charter for the City of Krakow, Poland, for Microbial Hazards.

    PubMed

    Lech, Tomasz

    2016-05-01

    The literature of environmental microbiology broadly discusses issues associated with microbial hazards in archives, but these publications are mainly devoted to paper documents. There are few articles on historical parchment documents, which used to be very important for the development of literature and the art of writing. These studies present a broad spectrum of methods for the assessment of biodeterioration hazards of the parchment document in question. They are based on both conventional microbiological methods and advanced techniques of molecular biology. Here, a qualitative analysis was conducted, based on genetic identification of bacteria and fungi present on the document as well as denaturing gradient gel electrophoresis profiling and examining the destructive potential of isolated microbes. Moreover, the study involved a quantitative and qualitative microbiological assessment of the indoor air in the room where the parchment was kept. The microbes with the highest destructive potential that were isolated from the investigated item were Bacillus cereus and Acinetobacter lwoffii bacteria and Penicillium chrysogenum,Chaetomium globosum, and Trichoderma longibrachiatum fungi. The presence of the B. cereuss train was particularly interesting since, under appropriate conditions, it leads to complete parchment degradation within several days. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  13. Toward identifying the next generation of superfund and hazardous waste site contaminants.

    PubMed

    Ela, Wendell P; Sedlak, David L; Barlaz, Morton A; Henry, Heather F; Muir, Derek C G; Swackhamer, Deborah L; Weber, Eric J; Arnold, Robert G; Ferguson, P Lee; Field, Jennifer A; Furlong, Edward T; Giesy, John P; Halden, Rolf U; Henry, Tala; Hites, Ronald A; Hornbuckle, Keri C; Howard, Philip H; Luthy, Richard G; Meyer, Anita K; Sáez, A Eduardo; Vom Saal, Frederick S; Vulpe, Chris D; Wiesner, Mark R

    2011-01-01

    This commentary evolved from a workshop sponsored by the National Institute of Environmental Health Sciences titled "Superfund Contaminants: The Next Generation" held in Tucson, Arizona, in August 2009. All the authors were workshop participants. Our aim was to initiate a dynamic, adaptable process for identifying contaminants of emerging concern (CECs) that are likely to be found in future hazardous waste sites, and to identify the gaps in primary research that cause uncertainty in determining future hazardous waste site contaminants. Superfund-relevant CECs can be characterized by specific attributes: They are persistent, bioaccumulative, toxic, occur in large quantities, and have localized accumulation with a likelihood of exposure. Although still under development and incompletely applied, methods to quantify these attributes can assist in winnowing down the list of candidates from the universe of potential CECs. Unfortunately, significant research gaps exist in detection and quantification, environmental fate and transport, health and risk assessment, and site exploration and remediation for CECs. Addressing these gaps is prerequisite to a preventive approach to generating and managing hazardous waste sites. A need exists for a carefully considered and orchestrated expansion of programmatic and research efforts to identify, evaluate, and manage CECs of hazardous waste site relevance, including developing an evolving list of priority CECs, intensifying the identification and monitoring of likely sites of present or future accumulation of CECs, and implementing efforts that focus on a holistic approach to prevention.

  14. Bacillus “next generation” diagnostics: moving from detection toward subtyping and risk-related strain profiling

    PubMed Central

    Ehling-Schulz, Monika; Messelhäusser, Ute

    2013-01-01

    The highly heterogeneous genus Bacillus comprises the largest species group of endospore forming bacteria. Because of their ubiquitous nature, Bacillus spores can enter food production at several stages resulting in significant economic losses and posing a potential risk to consumers due the capacity of certain Bacillus strains for toxin production. In the past, food microbiological diagnostics was focused on the determination of species using conventional culture-based methods, which are still widely used. However, due to the extreme intra-species diversity found in the genus Bacillus, DNA-based identification and typing methods are gaining increasing importance in routine diagnostics. Several studies showed that certain characteristics are rather strain-dependent than species-specific. Therefore, the challenge for current and future Bacillus diagnostics is not only the efficient and accurate identification on species level but also the development of rapid methods to identify strains with specific characteristics (such as stress resistance or spoilage potential), trace contamination sources, and last but not least discriminate potential hazardous strains from non-toxic strains. PMID:23440299

  15. Review article: the use of remotely piloted aircraft systems (RPASs) for natural hazards monitoring and management

    NASA Astrophysics Data System (ADS)

    Giordan, Daniele; Hayakawa, Yuichi; Nex, Francesco; Remondino, Fabio; Tarolli, Paolo

    2018-04-01

    The number of scientific studies that consider possible applications of remotely piloted aircraft systems (RPASs) for the management of natural hazards effects and the identification of occurred damages strongly increased in the last decade. Nowadays, in the scientific community, the use of these systems is not a novelty, but a deeper analysis of the literature shows a lack of codified complex methodologies that can be used not only for scientific experiments but also for normal codified emergency operations. RPASs can acquire on-demand ultra-high-resolution images that can be used for the identification of active processes such as landslides or volcanic activities but can also define the effects of earthquakes, wildfires and floods. In this paper, we present a review of published literature that describes experimental methodologies developed for the study and monitoring of natural hazards.

  16. DTREEv2, a computer-based support system for the risk assessment of genetically modified plants.

    PubMed

    Pertry, Ine; Nothegger, Clemens; Sweet, Jeremy; Kuiper, Harry; Davies, Howard; Iserentant, Dirk; Hull, Roger; Mezzetti, Bruno; Messens, Kathy; De Loose, Marc; de Oliveira, Dulce; Burssens, Sylvia; Gheysen, Godelieve; Tzotzos, George

    2014-03-25

    Risk assessment of genetically modified organisms (GMOs) remains a contentious area and a major factor influencing the adoption of agricultural biotech. Methodologically, in many countries, risk assessment is conducted by expert committees with little or no recourse to databases and expert systems that can facilitate the risk assessment process. In this paper we describe DTREEv2, a computer-based decision support system for the identification of hazards related to the introduction of GM-crops into the environment. DTREEv2 structures hazard identification and evaluation by means of an Event-Tree type of analysis. The system produces an output flagging identified hazards and potential risks. It is intended to be used for the preparation and evaluation of biosafety dossiers and, as such, its usefulness extends to researchers, risk assessors and regulators in government and industry. Copyright © 2013 Elsevier B.V. All rights reserved.

  17. Recording and cataloging hazards information, revision A

    NASA Technical Reports Server (NTRS)

    Stein, R. J.

    1974-01-01

    A data collection process is described for the purpose of discerning causation factors of accidents, and the establishment of boundaries or controls aimed at mitigating and eliminating accidents. A procedure is proposed that suggests a discipline approach to hazard identification based on energy interrelationships together with an integrated control technique which takes the form of checklists.

  18. 41 CFR 101-42.202 - Identification of hazardous materials.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...'s Federal Supply Service (4FQ) maintains an automated data base, accessible via modem and computer... on the terminal screen, the system allows for the addition of the MSDS to the user's local data base... personnel who handle, store, ship, use or dispose of hazardous materials. Each record in the data base is...

  19. 41 CFR 101-42.202 - Identification of hazardous materials.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...'s Federal Supply Service (4FQ) maintains an automated data base, accessible via modem and computer... on the terminal screen, the system allows for the addition of the MSDS to the user's local data base... personnel who handle, store, ship, use or dispose of hazardous materials. Each record in the data base is...

  20. 41 CFR 101-42.202 - Identification of hazardous materials.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...'s Federal Supply Service (4FQ) maintains an automated data base, accessible via modem and computer... on the terminal screen, the system allows for the addition of the MSDS to the user's local data base... personnel who handle, store, ship, use or dispose of hazardous materials. Each record in the data base is...

  1. 41 CFR 101-42.202 - Identification of hazardous materials.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...'s Federal Supply Service (4FQ) maintains an automated data base, accessible via modem and computer... on the terminal screen, the system allows for the addition of the MSDS to the user's local data base... personnel who handle, store, ship, use or dispose of hazardous materials. Each record in the data base is...

  2. 41 CFR 101-42.202 - Identification of hazardous materials.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...'s Federal Supply Service (4FQ) maintains an automated data base, accessible via modem and computer... on the terminal screen, the system allows for the addition of the MSDS to the user's local data base... personnel who handle, store, ship, use or dispose of hazardous materials. Each record in the data base is...

  3. 40 CFR 261.141 - Definitions of terms as used in this subpart.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) SOLID WASTES (CONTINUED) IDENTIFICATION AND LISTING OF HAZARDOUS WASTE Financial Requirements for Management of Excluded Hazardous Secondary Materials § 261.141 Definitions of terms as used in this subpart... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Definitions of terms as used in this...

  4. Further Evaluation of DNT Hazard Screening using Neural Networks from Rat Cortical Neurons on Multi-well Microelectrode Arrays

    EPA Science Inventory

    Thousands of chemicals have not been characterized for their DNT potential. Due to the need for DNT hazard identification, efforts to develop screening assays for DNT potential is a high priority. Multi-well microelectrode arrays (MEA) measure the spontaneous activity of electr...

  5. 77 FR 36447 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-19

    ... the point of waste generation. C. How did ExxonMobil sample and analyze the data in this petition? To support its petition, ExxonMobil submitted: (1) Historical information on waste generation and management... North Landfarm underflow water twice during the first six months of waste generation. ExxonMobil would...

  6. 77 FR 56558 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Final Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-13

    ... determination (regarding a federally regulated waste), the delisting determination takes effect within that... from taking effect in the state, or that requires a State concurrence before the federal exclusion takes effect, or that allows the State to add conditions to any federal exclusion. We urge the...

  7. 76 FR 72311 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Final Exclusion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-23

    ... waste in any State with delisting authorization, Eastman Chemical must obtain delisting authorization... benzene, ethyl ether, methyl isobutyl ketone, n-butyl alcohol, cyclohexane, methanol. F005 Toluene, methyl... Isobutyl alcohol. U147 Maleic anhydride. U154 Methanol. U159 Methyl ethyl ketone. U161 Methyl isobutyl...

  8. Brief Alcohol Interventions and Multiple Risk Factors in Primary Care

    ERIC Educational Resources Information Center

    Funderburk, Jennifer S.; Maisto, Stephen A.; Sugarman, Dawn E.

    2007-01-01

    Early identification and intervention of harmful/hazardous drinking in primary care are U.S. healthcare priorities. Traditionally, research has focused on designing interventions for patients in primary care who report hazardous/harmful alcohol use, even though it is likely for a patient to be at risk for multiple problems. This article has three…

  9. Non-target screening of Allura Red AC photodegradation products in a beverage through ultra high performance liquid chromatography coupled with hybrid triple quadrupole/linear ion trap mass spectrometry.

    PubMed

    Gosetti, Fabio; Chiuminatto, Ugo; Mazzucco, Eleonora; Calabrese, Giorgio; Gennaro, Maria Carla; Marengo, Emilio

    2013-01-15

    The study deals with the identification of the degradation products formed by simulated sunlight photoirradiation in a commercial beverage that contains Allura Red AC dye. An UHPLC-MS/MS method, that makes use of hybrid triple quadrupole/linear ion trap, was developed. In the identification step the software tool information dependent acquisition (IDA) was used to automatically obtain information about the species present and to build a multiple reaction monitoring (MRM) method with the MS/MS fragmentation pattern of the species considered. The results indicate that the identified degradation products are formed from side-reactions and/or interactions among the dye and other ingredients present in the beverage (ascorbic acid, citric acid, sucrose, aromas, strawberry juice, and extract of chamomile flowers). The presence of aromatic amine or amide functionalities in the chemical structures proposed for the degradation products might suggest potential hazards to consumer health. Copyright © 2012 Elsevier Ltd. All rights reserved.

  10. The identification and classification of skin irritation hazard by a human patch test.

    PubMed

    Basketter, D A; Whittle, E; Griffiths, H A; York, M

    1994-08-01

    There exist various regulatory instruments the purpose of which is to ensure that the intrinsic toxic hazards associated with substances and preparations are identified. In the context of identification of skin irritation potential, the method is normally the Draize test. Guidance notes provided by the OECD and the EEC expect that corrosive substances will have been screened out by a variety of methods. Substances or preparations which cause a sufficient degree of skin irritation will be classified as skin irritants. The primary motivation behind the present work was to introduce the concept that it is possible to assess the hazard potential of a substance or preparation to produce skin irritation in a human study. In the example presented here, 20% sodium lauryl sulfate (SLS) has been chosen as the positive control. With the protocol currently devised, occluded patch treatment with 20% SLS for up to 4 hr produces an irritant response in just over half of the panel. An irritant response is taken as a clinically evident and significant increase in erythema, oedema or dryness--a minimum of a+ reaction on the ICDRG scale. At such a level of response with the positive control (both in terms of intensity and in proportion of the panel), it is then possible to judge and/or to determine statistically, whether the test material has produced a level of skin irritation which is similar to, greater, or lower than the positive control. In this way a human patch test protocol can form a fundamental component of a strategy for the replacement of animals in determination of skin irritation and corrosion potential. By use of a careful and progressive protocol and by comparison of test data against a positive control it is both possible and practical to classify substances and preparations in terms of their skin irritation potential using that endpoint in the species of concern, man.

  11. Forensic and homeland security applications of modern portable Raman spectroscopy.

    PubMed

    Izake, Emad L

    2010-10-10

    Modern detection and identification of chemical and biological hazards within the forensic and homeland security contexts may well require conducting the analysis in field while adapting a non-contact approach to the hazard. Technological achievements on both surface and resonance enhancement Raman scattering re-developed Raman spectroscopy to become the most adaptable spectroscopy technique for stand-off and non-contact analysis of hazards. On the other hand, spatially offset Raman spectroscopy proved to be very valuable for non-invasive chemical analysis of hazards concealed within non-transparent containers and packaging. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  12. 40 CFR 63.107 - Identification of process vents subject to this subpart.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... CATEGORIES National Emission Standards for Organic Hazardous Air Pollutants From the Synthetic Organic Chemical Manufacturing Industry § 63.107 Identification of process vents subject to this subpart. (a) The..., distillation unit, or reactor during operation of the chemical manufacturing process unit. (c) The discharge to...

  13. 40 CFR 63.107 - Identification of process vents subject to this subpart.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... CATEGORIES National Emission Standards for Organic Hazardous Air Pollutants From the Synthetic Organic Chemical Manufacturing Industry § 63.107 Identification of process vents subject to this subpart. (a) The..., distillation unit, or reactor during operation of the chemical manufacturing process unit. (c) The discharge to...

  14. 40 CFR 63.107 - Identification of process vents subject to this subpart.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... CATEGORIES National Emission Standards for Organic Hazardous Air Pollutants From the Synthetic Organic Chemical Manufacturing Industry § 63.107 Identification of process vents subject to this subpart. (a) The..., distillation unit, or reactor during operation of the chemical manufacturing process unit. (c) The discharge to...

  15. 40 CFR 63.1589 - What records must I keep?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Standards for Hazardous Air Pollutants: Publicly Owned Treatment Works Non-Industrial Potw Treatment Plant... section: (1) A record for each treatment unit inspection required by § 63.1588(a). You must include a treatment unit identification number (or other unique identification description as selected by you) and the...

  16. Plenary lecture: innovative modeling approaches applicable to risk assessments

    USDA-ARS?s Scientific Manuscript database

    Proper identification of safe and unsafe food at the processing plant is important for maximizing the public health benefit of food by ensuring both its consumption and safety. Risk assessment is a holistic approach to food safety that consists of four steps: 1) hazard identification; 2) exposure a...

  17. 49 CFR 172.334 - Identification numbers; prohibited display.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... or 1.6, DANGEROUS, or subsidiary hazard placard. (b) No person may display an identification number on a placard, orange panel or white square-on-point display configuration unless— (1) The... the placard, orange panel or white square-on-point configuration authorized by § 172.332 or § 172.336...

  18. 49 CFR 172.334 - Identification numbers; prohibited display.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... or 1.6, DANGEROUS, or subsidiary hazard placard. (b) No person may display an identification number on a placard, orange panel or white square-on-point display configuration unless— (1) The... the placard, orange panel or white square-on-point configuration authorized by § 172.332 or § 172.336...

  19. 49 CFR 172.334 - Identification numbers; prohibited display.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... or 1.6, DANGEROUS, or subsidiary hazard placard. (b) No person may display an identification number on a placard, orange panel or white square-on-point display configuration unless— (1) The... the placard, orange panel or white square-on-point configuration authorized by § 172.332 or § 172.336...

  20. 49 CFR 172.334 - Identification numbers; prohibited display.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... or 1.6, DANGEROUS, or subsidiary hazard placard. (b) No person may display an identification number on a placard, orange panel or white square-on-point display configuration unless— (1) The... the placard, orange panel or white square-on-point configuration authorized by § 172.332 or § 172.336...

  1. 49 CFR 172.334 - Identification numbers; prohibited display.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... or 1.6, DANGEROUS, or subsidiary hazard placard. (b) No person may display an identification number on a placard, orange panel or white square-on-point display configuration unless— (1) The... the placard, orange panel or white square-on-point configuration authorized by § 172.332 or § 172.336...

  2. Modified extraction procedure for gas-liquid chromatography applied to the identification of anaerobic bacteria.

    PubMed Central

    Thomann, W R; Hill, G B

    1986-01-01

    Chloroform and ether commonly are used as solvents to extract metabolic organic acids for analysis by gas-liquid chromatography in the identification of anaerobic bacteria. Because these solvents are potentially hazardous to personnel, modified extraction procedures involving the use of a safer solvent, methyl tert-butyl ether were developed which remained both simple to perform and effective for organism identification. PMID:3700623

  3. A modeling framework for investment planning in interdependent infrastructures in multi-hazard environments.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, Nathanael J. K.; Gearhart, Jared Lee; Jones, Dean A.

    Currently, much of protection planning is conducted separately for each infrastructure and hazard. Limited funding requires a balance of expenditures between terrorism and natural hazards based on potential impacts. This report documents the results of a Laboratory Directed Research & Development (LDRD) project that created a modeling framework for investment planning in interdependent infrastructures focused on multiple hazards, including terrorism. To develop this framework, three modeling elements were integrated: natural hazards, terrorism, and interdependent infrastructures. For natural hazards, a methodology was created for specifying events consistent with regional hazards. For terrorism, we modeled the terrorists actions based on assumptions regardingmore » their knowledge, goals, and target identification strategy. For infrastructures, we focused on predicting post-event performance due to specific terrorist attacks and natural hazard events, tempered by appropriate infrastructure investments. We demonstrate the utility of this framework with various examples, including protection of electric power, roadway, and hospital networks.« less

  4. Using hazard maps to identify and eliminate workplace hazards: a union-led health and safety training program.

    PubMed

    Anderson, Joe; Collins, Michele; Devlin, John; Renner, Paul

    2012-01-01

    The Institute for Sustainable Work and Environment and the Utility Workers Union of America worked with a professional evaluator to design, implement, and evaluate the results of a union-led system of safety-based hazard identification program that trained workers to use hazard maps to identify workplace hazards and target them for elimination. The evaluation documented program implementation and impact using data collected from both qualitative interviews and an on-line survey from worker trainers, plant managers, and health and safety staff. Managers and workers reported that not only were many dangerous hazards eliminated as a result of hazard mapping, some of which were long-standing, difficult-to-resolve issues, but the evaluation also documented improved communication between union members and management that both workers and managers agreed resulted in better, more sustainable hazard elimination.

  5. Using Climate Information for Disaster Risk Identification in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Zubair, L.

    2004-12-01

    We have engaged in a concerted attempt to undertake research and apply earth science information for development in Sri Lanka, with a focus on climate sciences. Here, we provide details of an ongoing attempt to harness science for disaster identification as a prelude to informed disaster management. Natural disasters not only result in death and destruction but also undermine decades of development gains as highlighted by recent examples from Sri Lanka. First, in May 2003, flooding and landslides in the South-West led to 260 deaths, damage to 120,000 homes and destruction of schools, infrastructure and agricultural land. Second, on December 26, 2000, a cyclone in the North-Central region left 8 dead, 55,000 displaced, with severe damage to fishing, agriculture, infrastructure and cultural sites. Third, an extended island-wide drought in 2001 and 2002 resulted in a 2% drop in GDP. In the aftermath of these disasters, improved disaster management has been deemed to be urgent by the Government of Sri Lanka. In the past the primary policy response to disasters was to provide emergency relief. It is increasingly recognized that appropriate disaster risk management, including risk assessment, preventive measures to reduce losses and improved preparedness, can help reduce death, destruction and socio-economic disruption. The overwhelming majority of hazards in Sri Lanka - droughts, floods, cyclones and landslides -have hydro-meteorological antecedents. Little systematic advantage has, however, been taken of hydro-meteorological information and advances in climate prediction for disaster management. Disaster risks are created by the interaction between hazard events and vulnerabilities of communities, infrastructure and economically important activities. A comprehensive disaster risk management system encompasses risk identification, risk reduction and risk transfer. We undertook an identification of risks for Sri Lanka at fine scale with the support of the Global Disaster Hotspots project of the Earth Institute at Columbia University. We developed tools that translate meteorological, environmental and socio-economic exposure and vulnerability information into assessments of relevant hazard related disaster risk at appropriate spatial and temporal scales. We also developed high-resolution predictive capabilities for assessing seasonal hazard event. We found that useful hazard risk and vulnerability analysis can be carried out with the type of data that is available in Sri Lanka with sufficiently fine scale as to be useful for national level planning and action. Also, hydro-meteorological information was essential to estimate hazard risks. This analysis brought out a distinct seasonality to drought, floods, landslides and cyclone hazards in Sri Lanka. This work provides a foundation for systematic disaster management that shall manage risks through measures such as hazard warnings, scenario-based relief identification and planning, strategic river basin management, risk mapping and land use zoning, standards for construction and infrastructure. The fostering of research and application capacity in the vulnerable community leads to the appropriate and sustainable use of earth science information. This work contributes to the mitigation of risk of vulnerable communities and provides an example of the harnessing of geosciences for poverty alleviation and improvement of human well-being. Note: The contributions of Vidhura Ralapanawe, Upamala Tennakoon, Ruvini Perera, Maxx Dilley, Bob Chen and the Hotspots team are gratefully acknowledged.

  6. Potential slab avalanche release area identification from estimated winter terrain: a multi-scale, fuzzy logic approach

    NASA Astrophysics Data System (ADS)

    Veitinger, Jochen; Purves, Ross Stuart; Sovilla, Betty

    2016-10-01

    Avalanche hazard assessment requires a very precise estimation of the release area, which still depends, to a large extent, on expert judgement of avalanche specialists. Therefore, a new algorithm for automated identification of potential avalanche release areas was developed. It overcomes some of the limitations of previous tools, which are currently not often applied in hazard mitigation practice. By introducing a multi-scale roughness parameter, fine-scale topography and its attenuation under snow influence is captured. This allows the assessment of snow influence on terrain morphology and, consequently, potential release area size and location. The integration of a wind shelter index enables the user to define release area scenarios as a function of the prevailing wind direction or single storm events. A case study illustrates the practical usefulness of this approach for the definition of release area scenarios under varying snow cover and wind conditions. A validation with historical data demonstrated an improved estimation of avalanche release areas. Our method outperforms a slope-based approach, in particular for more frequent avalanches; however, the application of the algorithm as a forecasting tool remains limited, as snowpack stability is not integrated. Future research activity should therefore focus on the coupling of the algorithm with snowpack conditions.

  7. Identification of the Polaris Fault using lidar and shallow geophysical methods

    USGS Publications Warehouse

    Hunter, Lewis E.; Powers, Michael H.; Burton, Bethany L.

    2017-01-01

    As part of the U.S. Army Corps of Engineers' (USACE) Dam Safety Assurance Program, Martis Creek Dam near Truckee, CA, is under evaluation for earthquake and seepage hazards. The investigations to date have included LiDAR (Light Detection and Ranging) and a wide range of geophysical surveys. The LiDAR data led to the discovery of an important and previously unknown fault tracing very near and possibly under Martis Creek Dam. The geophysical surveys of the dam foundation area confirm evidence of the fault in the area.

  8. Thresholds in chemical respiratory sensitisation.

    PubMed

    Cochrane, Stella A; Arts, Josje H E; Ehnes, Colin; Hindle, Stuart; Hollnagel, Heli M; Poole, Alan; Suto, Hidenori; Kimber, Ian

    2015-07-03

    There is a continuing interest in determining whether it is possible to identify thresholds for chemical allergy. Here allergic sensitisation of the respiratory tract by chemicals is considered in this context. This is an important occupational health problem, being associated with rhinitis and asthma, and in addition provides toxicologists and risk assessors with a number of challenges. In common with all forms of allergic disease chemical respiratory allergy develops in two phases. In the first (induction) phase exposure to a chemical allergen (by an appropriate route of exposure) causes immunological priming and sensitisation of the respiratory tract. The second (elicitation) phase is triggered if a sensitised subject is exposed subsequently to the same chemical allergen via inhalation. A secondary immune response will be provoked in the respiratory tract resulting in inflammation and the signs and symptoms of a respiratory hypersensitivity reaction. In this article attention has focused on the identification of threshold values during the acquisition of sensitisation. Current mechanistic understanding of allergy is such that it can be assumed that the development of sensitisation (and also the elicitation of an allergic reaction) is a threshold phenomenon; there will be levels of exposure below which sensitisation will not be acquired. That is, all immune responses, including allergic sensitisation, have threshold requirement for the availability of antigen/allergen, below which a response will fail to develop. The issue addressed here is whether there are methods available or clinical/epidemiological data that permit the identification of such thresholds. This document reviews briefly relevant human studies of occupational asthma, and experimental models that have been developed (or are being developed) for the identification and characterisation of chemical respiratory allergens. The main conclusion drawn is that although there is evidence that the acquisition of sensitisation to chemical respiratory allergens is a dose-related phenomenon, and that thresholds exist, it is frequently difficult to define accurate numerical values for threshold exposure levels. Nevertheless, based on occupational exposure data it may sometimes be possible to derive levels of exposure in the workplace, which are safe. An additional observation is the lack currently of suitable experimental methods for both routine hazard characterisation and the measurement of thresholds, and that such methods are still some way off. Given the current trajectory of toxicology, and the move towards the use of non-animal in vitro and/or in silico) methods, there is a need to consider the development of alternative approaches for the identification and characterisation of respiratory sensitisation hazards, and for risk assessment. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  9. Strongly Iridescent Hybrid Photonic Sensors Based on Self-Assembled Nanoparticles for Hazardous Solvent Detection.

    PubMed

    Sato, Ayaka; Ikeda, Yuya; Yamaguchi, Koichi; Vohra, Varun

    2018-03-16

    Facile detection and the identification of hazardous organic solvents are essential for ensuring global safety and avoiding harm to the environment caused by industrial wastes. Here, we present a simple method for the fabrication of silver-coated monodisperse polystyrene nanoparticle photonic structures that are embedded into a polydimethylsiloxane (PDMS) matrix. These hybrid materials exhibit a strong green iridescence with a reflectance peak at 550 nm that originates from the close-packed arrangement of the nanoparticles. This reflectance peak measured under Wulff-Bragg conditions displays a 20 to 50 nm red shift when the photonic sensors are exposed to five commonly employed and highly hazardous organic solvents. These red-shifts correlate well with PDMS swelling ratios using the various solvents, which suggests that the observable color variations result from an increase in the photonic crystal lattice parameter with a similar mechanism to the color modulation of the chameleon skin. Dynamic reflectance measurements enable the possibility of clearly identifying each of the tested solvents. Furthermore, as small amounts of hazardous solvents such as tetrahydrofuran can be detected even when mixed with water, the nanostructured solvent sensors we introduce here could have a major impact on global safety measures as innovative photonic technology for easily visualizing and identifying the presence of contaminants in water.

  10. 76 FR 48073 - Hazardous Waste Management System: Identification and Listing of Hazardous Waste: Carbon Dioxide...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-08

    ... Science Basis. Contribution of Working Group I to the Fourth Assessment Report of the Intergovernmental Panel on Climate Change [Solomon, S., D. Qin, M. Manning, Z. Chen, M. Marquis, K.B. Averyt, M. Tignor... Vulnerability. Contribution of Working Group II to the Fourth Assessment Report of the Intergovernmental Panel...

  11. 76 FR 76677 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Proposed Exclusion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-08

    ... filter press and/or portable centrifuge, and the resulting residual solids are disposed of in a RCRA... dewatered and de- oiled using a filter press and/or portable centrifuge and the resulting solids disposed in... tanks at approximately 18 month intervals and processed via centrifuge and/or filter press for oil...

  12. 76 FR 74709 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Final Exclusion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-01

    ... stated that ExxonMobil's waste is not subject to the LDR standards, because the waste was not delisted at the point of generation, ExxonMobil may submit a variance to the treatment standards as described in... granting a petition submitted by ExxonMobil Refining and Supply Company--Beaumont Refinery (Beaumont...

  13. Evaluation of In Vitro Biotransformation Using HepaRG Cells to Improve High-Throughput Chemical Hazard Prediction: A Toxicogenomics Analysis (SOT)

    EPA Science Inventory

    The US EPA’s ToxCast program has generated a wealth of data in >600 in vitro assayson a library of 1060 environmentally relevant chemicals and failed pharmaceuticals to facilitate hazard identification. An inherent criticism of many in vitro-based strategies is the inability of a...

  14. 75 FR 11002 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Final Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... effect in the State. A dual system (that is, both Federal (RCRA) and State (non-RCRA) programs) may... does not have federalism implications. It will not have substantial direct effects on the States, on... Act of 1996, generally provides that before a rule may take effect, the agency promulgating the rule...

  15. 76 FR 16534 - Hazardous Waste Management System Identification and Listing of Hazardous Waste; Final Exclusion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-24

    ... issued exclusion from taking effect in the State until the State approves the exclusion through a..., this final rule does not have federalism implications. It will not have substantial direct effects on... provides that before a rule may take effect, the agency promulgating the rule must submit a rule report...

  16. 75 FR 58315 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Direct Final...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... benzene, ethyl ether, methyl isobutyl ketone, n-butyl alcohol, cyclohexane, methanol. F005 Toluene, methyl... alcohol. U147 Maleic anhydride. U154 Methanol. U159 Methyl ethyl ketone. U161 Methyl isobutyl ketone. U213..., methyl isobutyl ketone, n-butyl alcohol, cyclohexane, methanol. F005 Toluene, methyl ethyl ketone, carbon...

  17. 77 FR 58315 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Final Exclusion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-20

    ... E (Phosphorus), and 1613B (Dioxins and Furans). The laboratory Quality Assurance Plan (Attachment 2... fine sand layer that underlies the North Landfarm but overlies a clay liner. Within said sand layer are... Quality Objectives are to demonstrate that samples of the ExxonMobil North Landfarm underflow water are...

  18. Identification and Validation of Agricultural Hazardous Occupations Order Certification Program Instructor Criteria and Competencies

    ERIC Educational Resources Information Center

    Snyder, Shannon; French, Brian; Field, William; Tormoehlen, Roger; Ess, Daniel

    2013-01-01

    The USDA/NIFA has awarded funding to Land Grant Institutions to conduct and enhance the Hazardous Occupations Safety Training in Agriculture (HOSTA) program. The HOSTA program is designed to provide relevant educational opportunities in an effort to reduce the frequency and severity of farm-related injuries to all youth who work in agricultural…

  19. Omnisphero: a high-content image analysis (HCA) approach for phenotypic developmental neurotoxicity (DNT) screenings of organoid neurosphere cultures in vitro.

    PubMed

    Schmuck, Martin R; Temme, Thomas; Dach, Katharina; de Boer, Denise; Barenys, Marta; Bendt, Farina; Mosig, Axel; Fritsche, Ellen

    2017-04-01

    Current developmental neurotoxicity (DNT) testing in animals faces major limitations, such as high cost and time demands as well as uncertainties in their methodology, evaluation and regulation. Therefore, the use of human-based 3D in vitro systems in combination with high-content image analysis (HCA) might contribute to DNT testing with lower costs, increased throughput and enhanced predictivity for human hazard identification. Human neural progenitor cells (hNPCs) grown as 3D neurospheres mimic basic processes of brain development including hNPC migration and differentiation and are therefore useful for DNT hazard identification. HCA of migrated neurospheres creates new challenges for automated evaluations because it encompasses variable cell densities, inconsistent z-layers and heterogeneous cell populations. We tackle those challenges with our Omnisphero software, which assesses multiple endpoints of the 'Neurosphere Assay.' For neuronal identification, Omnisphero reaches a true positive rate (TPR) of 83.8 % and a false discovery rate (FDR) of 11.4 %, thus being comparable to the interindividual difference among two researchers (TPR = 94.3, FDR = 11.0 %) and largely improving the results obtained by an existing HCA approach, whose TPR does not exceed 50 % at a FDR above 50 %. The high FDR of existing methods results in incorrect measurements of neuronal morphological features accompanied by an overestimation of compound effects. Omnisphero additionally includes novel algorithms to assess 'neurosphere-specific' endpoints like radial migration and neuronal density distribution within the migration area. Furthermore, a user-assisted parameter optimization procedure makes Omnisphero accessible to non-expert end users.

  20. Toward the characterization of biological toxins using field-based FT-IR spectroscopic instrumentation

    NASA Astrophysics Data System (ADS)

    Schiering, David W.; Walton, Robert B.; Brown, Christopher W.; Norman, Mark L.; Brewer, Joseph; Scott, James

    2004-12-01

    IR spectroscopy is a broadly applicable technique for the identification of covalent materials. Recent advances in instrumentation have made Fourier Transform infrared (FT-IR) spectroscopy available for field characterization of suspect materials. Presently, this instrumentation is broadly deployed and used for the identification of potential chemical hazards. This discussion concerns work towards expanding the analytical utility of field-based FT-IR spectrometry in the characterization of biological threats. Two classes of materials were studied: biologically produced chemical toxins which were non-peptide in nature and peptide toxin. The IR spectroscopic identification of aflatoxin-B1, trichothecene T2 mycotoxin, and strychnine was evaluated using the approach of spectral searching against large libraries of materials. For pure components, the IR method discriminated the above toxins at better than the 99% confidence level. The ability to identify non-peptide toxins in mixtures was also evaluated using a "spectral stripping" search approach. For the mixtures evaluated, this method was able to identify the mixture components from ca. 32K spectral library entries. Castor bean extract containing ricin was used as a representative peptide toxin. Due to similarity in protein spectra, a SIMCA pattern recognition methodology was evaluated for classifying peptide toxins. In addition to castor bean extract the method was validated using bovine serum albumin and myoglobin as simulants. The SIMCA approach was successful in correctly classifying these samples at the 95% confidence level.

  1. [Chemical hazards in the workplace environment of painting restorer].

    PubMed

    Jezewska, Anna; Szewczyńska, Małgorzata

    2012-01-01

    This paper presents the results of the identification of chemical substances present in the air in the workplace of painting restorer. Identification tests were carried out in university and museum easel paintings conservation studios. Air samples were taken for testing at various stages of restoration works. In the qualitative analysis chemical substances in the air samples were measured by GC-MSD and HPLC-DAD methods. In the air samples collected during the cleaning of paintings, such substances as aliphatic and aromatic hydrocarbons, acetone, ethanol and terpenes were mainly identified. While the painting was doubled toluene and while varnished, propan-2-ol, propane, butane and substances derived from turpentine and white spirit were mainly emitted. During the course of painting conservation numerous chemical substances that may pose a threat to the worker's health were identified in their breathing zone.

  2. Advances in DNA metabarcoding for food and wildlife forensic species identification.

    PubMed

    Staats, Martijn; Arulandhu, Alfred J; Gravendeel, Barbara; Holst-Jensen, Arne; Scholtens, Ingrid; Peelen, Tamara; Prins, Theo W; Kok, Esther

    2016-07-01

    Species identification using DNA barcodes has been widely adopted by forensic scientists as an effective molecular tool for tracking adulterations in food and for analysing samples from alleged wildlife crime incidents. DNA barcoding is an approach that involves sequencing of short DNA sequences from standardized regions and comparison to a reference database as a molecular diagnostic tool in species identification. In recent years, remarkable progress has been made towards developing DNA metabarcoding strategies, which involves next-generation sequencing of DNA barcodes for the simultaneous detection of multiple species in complex samples. Metabarcoding strategies can be used in processed materials containing highly degraded DNA e.g. for the identification of endangered and hazardous species in traditional medicine. This review aims to provide insight into advances of plant and animal DNA barcoding and highlights current practices and recent developments for DNA metabarcoding of food and wildlife forensic samples from a practical point of view. Special emphasis is placed on new developments for identifying species listed in the Convention on International Trade of Endangered Species (CITES) appendices for which reliable methods for species identification may signal and/or prevent illegal trade. Current technological developments and challenges of DNA metabarcoding for forensic scientists will be assessed in the light of stakeholders' needs.

  3. Fine-tuned evaluation of olfactory function in patients operated for nasal polyposis.

    PubMed

    Sonnet, Marie-Hortense; Nguyen, Duc Trung; Nguyen-Thi, Phi-Linh; Arous, Fabien; Jankowski, Roger; Rumeau, Cécile

    2017-07-01

    Given the forced-choice procedure of the identification test, patients with profound anosmia are more likely to have higher identification scores by chance than patients with hyposmia or normosmia. This may be a confusing factor when assessing the sense of smell, which alters the appreciation of real olfaction improvement. The aim of this study was to fine-tune the results of the identification Sniffin' Sticks test before and 6 weeks after surgery using the real identification score. A total of 133 patients underwent the Identification (I) and Threshold (T) tests the day before and 6 weeks after nasalization surgery. The scores of the identification test, called I G (global identification), were ranked from 0 to 16. Patients had to specify if their forced-choice answers were given either surely or randomly, called I H (hazard identification). The real score of identification I R was obtained as follow: I R  = I G  - I H . Patients with an immeasurable threshold according to the T test were more prone to give randomly correct answers. On the basis of I G scores, 43.6% of patients remained hypo-anosmic after surgery compared to 72.9% before surgery. Using I R scores, only 3.8% of patients remained anosmic (I R  = 0) at 6 weeks after surgery. Hence, patients with real anosmia (I R  = 0) were less prone to improve their olfaction than patients with I R  > 0. The analysis of random factor when using identification test allows differentiating a real anosmia from a hyposmia. An I G  ≤ 4 could be considered as a profound/real anosmia or a severe hyposmia. This procedure cannot, however, replace the forced-choice method in odor identification testing.

  4. Assessment of the Acute and Chronic Health Hazards of Hydraulic Fracturing Fluids.

    PubMed

    Wattenberg, Elizabeth V; Bielicki, Jeffrey M; Suchomel, Ashley E; Sweet, Jessica T; Vold, Elizabeth M; Ramachandran, Gurumurthy

    2015-01-01

    There is growing concern about how hydraulic fracturing affects public health because this activity involves handling large volumes of fluids that contain toxic and carcinogenic constituents, which are injected under high pressure through wells into the subsurface to release oil and gas from tight shale formations. The constituents of hydraulic fracturing fluids (HFFs) present occupational health risks because workers may be directly exposed to them, and general public health risks because of potential air and water contamination. Hazard identification, which focuses on the types of toxicity that substances may cause, is an important step in the complex health risk assessment of hydraulic fracturing. This article presents a practical and adaptable tool for the hazard identification of HFF constituents, and its use in the analysis of HFF constituents reported to be used in 2,850 wells in North Dakota between December 2009 and November 2013. Of the 569 reported constituents, 347 could be identified by a Chemical Abstract Service Registration Number (CASRN) and matching constituent name. The remainder could not be identified either because of trade secret labeling (210) or because of an invalid CASRN (12). Eleven public databases were searched for health hazard information on thirteen health hazard endpoints for 168 identifiable constituents that had at least 25 reports of use. Health hazard counts were generated for chronic and acute endpoints, including those associated with oral, inhalation, ocular, and dermal exposure. Eleven of the constituents listed in the top 30 by total health hazard count were also listed in the top 30 by reports of use. This includes naphthalene, which along with benzyl chloride, has the highest health hazard count. The top 25 constituents reportedly used in North Dakota largely overlap with those reported for Texas and Pennsylvania, despite different geologic formations, target resources (oil vs. gas), and disclosure requirements. Altogether, this database provides a public health tool to help inform stakeholders about potential health hazards, and to aid in the reformulation of less hazardous HFFs.

  5. Real-Time Identification and Characterization of Asbestos and Concrete Materials with Radioactive Contamination

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xu, George; Zhang, Xi-Cheng

    Concrete and asbestos-containing materials were widely used in U.S. Department of Energy (DOE) building construction in the 1940s and 1950s. Over the years, many of these porous building materials have been contaminated with radioactive sources, on and below the surface. This intractable radioactive-and-hazardous- asbestos mixed-waste-stream has created a tremendous challenge to DOE decontamination and decommissioning (D&D) project managers. The current practice to identify asbestos and to characterize radioactive contamination depth profiles involve bore sampling, and is inefficient, costly, and unsafe. A three-year research project was started on 10/1/98 at Rensselaer with the following ultimate goals: (1) development of novel non-destructivemore » methods for identifying the hazardous asbestos in real-time and in-situ, and (2) development of new algorithms and apparatus for characterizing the radioactive contamination depth profile in real-time and in-situ.« less

  6. Real-Time Identification and Characterization of Asbestos and Concrete Materials with Radioactive Contamination

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xu, George; Zhang, Xi-Cheng

    Concrete and asbestos-containing materials were widely used in U.S. Department of Energy (DOE) building construction in the 1940s and 1950s. Over the years, many of these porous building materials have been contaminated with radioactive sources, on and below the surface. This intractable radioactive-and-hazardous-asbestos mixed-waste stream has created a tremendous challenge to DOE decontamination and decommissioning (D&D) project managers. The current practice to identify asbestos and to characterize radioactive contamination depth profiles in based solely on bore sampling, which is inefficient, costly, and unsafe. A three-year research project was started 1998 at Rensselaer with the following ultimate goals: (1) development ofmore » novel non-destructive methods for identifying the hazardous asbestos in real-time and in-situ, and (2) development of new algorithms and apparatus for characterizing the radioactive contamination depth profile in real-time and in-situ.« less

  7. Stream network analysis and geomorphic flood plain mapping from orbital and suborbital remote sensing imagery application to flood hazard studies in central Texas

    NASA Technical Reports Server (NTRS)

    Baker, V. R. (Principal Investigator); Holz, R. K.; Hulke, S. D.; Patton, P. C.; Penteado, M. M.

    1975-01-01

    The author has identified the following significant results. Development of a quantitative hydrogeomorphic approach to flood hazard evaluation was hindered by (1) problems of resolution and definition of the morphometric parameters which have hydrologic significance, and (2) mechanical difficulties in creating the necessary volume of data for meaningful analysis. Measures of network resolution such as drainage density and basin Shreve magnitude indicated that large scale topographic maps offered greater resolution than small scale suborbital imagery and orbital imagery. The disparity in network resolution capabilities between orbital and suborbital imagery formats depends on factors such as rock type, vegetation, and land use. The problem of morphometric data analysis was approached by developing a computer-assisted method for network analysis. The system allows rapid identification of network properties which can then be related to measures of flood response.

  8. Clinical and Serological Predictors of Suicide in Schizophrenia and Major Mood Disorders.

    PubMed

    Dickerson, Faith; Origoni, Andrea; Schweinfurth, Lucy A B; Stallings, Cassie; Savage, Christina L G; Sweeney, Kevin; Katsafanas, Emily; Wilcox, Holly C; Khushalani, Sunil; Yolken, Robert

    2018-03-01

    Persons with serious mental illness are at high risk for suicide, but this outcome is difficult to predict. Serological markers may help to identify suicide risk. We prospectively assessed 733 persons with a schizophrenia spectrum disorder, 483 with bipolar disorder, and 76 with major depressive disorder for an average of 8.15 years. The initial evaluation consisted of clinical and demographic data as well as a blood samples from which immunoglobulin G antibodies to herpes viruses and Toxoplasma gondii were measured. Suicide was determined using data from the National Death Index. Cox proportional hazard regression models examined the role of baseline variables on suicide outcomes. Suicide was associated with male sex, divorced/separated status, Caucasian race, and elevated levels of antibodies to Cytomegalovirus (CMV). Increasing levels of CMV antibodies were associated with increasing hazard ratios for suicide. The identification of serological variables associated with suicide might provide more personalized methods for suicide prevention.

  9. Global Assessment of Volcanic Debris Hazards from Space

    NASA Technical Reports Server (NTRS)

    Watters, Robert J.

    2003-01-01

    Hazard (slope stability) assessment for different sectors of volcano edifices was successfully obtained from volcanoes in North and South America. The assessment entailed Hyperion images to locate portions of the volcano that were hydrothermally altered to clay rich rocks with zones that were also rich in alunite and other minerals. The identified altered rock zones were field checked and sampled. The rock strength of these zones was calculated from the field and laboratory measurements. Volcano modeling utilizing the distinct element method and limit equilibrium technique, with the calculated strength data was used to assess stability and deformation of the edifice. Modeling results give indications of possible failure volumes, velocities and direction. The models show the crucial role hydrothermally weak rock plays in reducing the strength o the volcano edifice and the rapid identification of weak rock through remote sensing techniques. Volcanoes were assessed in the Cascade Range (USA), Mexico, and Chile (ongoing).

  10. Efficiency improvement by navigated safety inspection involving visual clutter based on the random search model.

    PubMed

    Sun, Xinlu; Chong, Heap-Yih; Liao, Pin-Chao

    2018-06-25

    Navigated inspection seeks to improve hazard identification (HI) accuracy. With tight inspection schedule, HI also requires efficiency. However, lacking quantification of HI efficiency, navigated inspection strategies cannot be comprehensively assessed. This work aims to determine inspection efficiency in navigated safety inspection, controlling for the HI accuracy. Based on a cognitive method of the random search model (RSM), an experiment was conducted to observe the HI efficiency in navigation, for a variety of visual clutter (VC) scenarios, while using eye-tracking devices to record the search process and analyze the search performance. The results show that the RSM is an appropriate instrument, and VC serves as a hazard classifier for navigation inspection in improving inspection efficiency. This suggests a new and effective solution for addressing the low accuracy and efficiency of manual inspection through navigated inspection involving VC and the RSM. It also provides insights into the inspectors' safety inspection ability.

  11. Skin sensitisation, vehicle effects and the local lymph node assay.

    PubMed

    Basketter, D A; Gerberick, G F; Kimber, I

    2001-06-01

    Accurate risk assessment in allergic contact dermatitis is dependent on the successful prospective identification of chemicals which possess the ability to behave as skin sensitisers, followed by appropriate measurement of the relative ability to cause sensitisation; their potency. Tools for hazard identification have been available for many years; more recently, a novel approach to the quantitative assessment of potency--the derivation of EC3 values in the local lymph node assay (LLNA)--has been described. It must be recognised, however, that these evaluations of chemical sensitisers also may be affected by the vehicle matrix in which skin exposure occurs. In this article, our knowledge of this area is reviewed and potential mechanisms through which vehicle effects may occur are detailed. Using the LLNA as an example, it is demonstrated that the vehicle may have little impact on the accuracy of basic hazard identification; the data also therefore support the view that testing ingredients in specific product formulations is not warranted for hazard identification purposes. However, the effect on potency estimations is of greater significance. Although not all chemical allergens are affected similarly, for certain substances a greater than 10-fold vehicle-dependent change in potency is observed. Such data are vital for accurate risk assessment. Unfortunately, it does not at present appear possible to predict notionally the effect of the vehicle matrix on skin sensitising potency without recourse to direct testing, for example by estimation of LLNA EC3 data, which provides a valuable tool for this purpose.

  12. Impact of the new handling recommendations for hazardous drugs in a hospital pharmacy service.

    PubMed

    García-Alcántara, Beatriz G; Perelló Alomar, Catalina; Moreno Centeno, Elena; Modamio, Pilar; Mariño, Eduardo L; Delgado Sánchez, Olga

    2017-03-01

    To describe the actions taken by the Pharmacy Unit in a tertiary hospital in order to adapt to the recommendations established by NIOSH 2014 for handling Hazardous Drugs. Method: A retrospective observational study. A list was prepared including all hazardous drugs according to NIOSH 2014 that were available at the hospital as marketed or foreign drugs, or used in clinical trials, and there was a review of the processes of acquisition, repackaging, preparation, circuits, organizational, dispensing and identification. Results: After the analysis, a report including all needs was prepared and sent to the Hospital Management. Any relevant information about the handling and administration of hazardous drugs was included in the prescription computer program. There were changes in the acquisition process of two drugs, in order to avoid splitting and multi-dose formulations. An alternative or improvement was found for 35 253 of the 75 779 units of hazardous drugs repackaged in one year. The Pharmacy Unit took over the preparation of four non-sterile medications, as well as the preparation of all sterile parenteral medications included in Lists 1 and 2 that were not previously prepared there, as well as one from List 3. Information was also included about the preparation processes of Magistral Formulations that involved hazardous drugs from Lists 2 or 3. The adaptation to the recommendations by NIOSH 2014 has represented a change, but also a significant reduction in the handling process of hazardous drugs by the healthcare staff, therefore reducing the risk of occupational exposure. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

  13. GPR survey, as one of the best geophysical methods for social and industrial needs

    NASA Astrophysics Data System (ADS)

    Chernov, Anatolii

    2016-04-01

    This paper is about ways and methods of applying non-invasive geophysical method - Ground penetrating radar (GPR) survey in different spheres of science, industry, social life and culture. Author would like to show that geological methods could be widely used for solving great variety of industrial, human safety and other problems. In that article, we take GPR survey as an example of such useful geophysical methods. It is a fact that investigation of near surface underground medium is important process, which influence on development of different spheres of science and social life: investigation of near surface geology (layering, spreading of rock types, identification of voids, etc.), hydrogeology (depth to water horizons, their thickness), preparation step for construction of roads and buildings (civil geology, engineering geology), investigation of cultural heritage (burial places, building remains,...), ecological investigations (land slides, variation in underground water level, etc.), glaciology. These tasks can be solved by geological methods, but as usual, geophysical survey takes a lot of time and energy (especially electric current and resistivity methods, seismic survey). Author claims that GPR survey can be performed faster than other geophysical surveys and results of GPR survey are informative enough to make proper conclusions. Some problems even cannot be solved without GPR. For example, identification of burial place (one of author's research objects): results of magnetic and electric resistivity tomography survey do not contain enough information to identify burial place, but according to anomalies on GPR survey radarograms, presence of burial place can be proven. Identification of voids and non-magnetic objects also hardly can be done by another non-invasive geophysics surveys and GPR is applicable for that purpose. GPR can be applied for monitoring of dangerous processes in geological medium under roads, buildings, parks and other places of human activity. Monitoring of such hazards as landslides, underground erosion, variation in ground water level can help prevent dangerous processes with destructive consequences, which can result in peoples' injuries and even death. Moreover, GPR can be used in other spheres of life, where investigation of hidden (under or behind conductive for electromagnetic wave material) objects is needed: rescue operations (finding of people after natural and human-made disasters under snow, under debris of building material); military purpose (security systems, identification of people presence through walls, doors, ground etc.). Author work on algorithms (first of all for VIY GPRs (http://viy.ua/)), which will help more precisely find objects of interest on radarograms and even solve inverse problem of geophysics. According to information in that article, geophysical methods can be widely used to solve great variety of tasks and help to investigate humans' past (researches of cultural heritage) and provide information to create safe and comfortable future (preventing of natural hazards and better planning of construction).

  14. The application of quality risk management to the bacterial endotoxins test: use of hazard analysis and critical control points.

    PubMed

    Annalaura, Carducci; Giulia, Davini; Stefano, Ceccanti

    2013-01-01

    Risk analysis is widely used in the pharmaceutical industry to manage production processes, validation activities, training, and other activities. Several methods of risk analysis are available (for example, failure mode and effects analysis, fault tree analysis), and one or more should be chosen and adapted to the specific field where they will be applied. Among the methods available, hazard analysis and critical control points (HACCP) is a methodology that has been applied since the 1960s, and whose areas of application have expanded over time from food to the pharmaceutical industry. It can be easily and successfully applied to several processes because its main feature is the identification, assessment, and control of hazards. It can be also integrated with other tools, such as fishbone diagram and flowcharting. The aim of this article is to show how HACCP can be used to manage an analytical process, propose how to conduct the necessary steps, and provide data templates necessary to document and useful to follow current good manufacturing practices. In the quality control process, risk analysis is a useful tool for enhancing the uniformity of technical choices and their documented rationale. Accordingly, it allows for more effective and economical laboratory management, is capable of increasing the reliability of analytical results, and enables auditors and authorities to better understand choices that have been made. The aim of this article is to show how hazard analysis and critical control points can be used to manage bacterial endotoxins testing and other analytical processes in a formal, clear, and detailed manner.

  15. Creating an Oversight Infrastructure for Electronic Health Record-Related Patient Safety Hazards

    PubMed Central

    Singh, Hardeep; Classen, David C.; Sittig, Dean F.

    2013-01-01

    Electronic health records (EHRs) have potential quality and safety benefits. However, reports of EHR-related safety hazards are now emerging. The Office of the National Coordinator (ONC) for Health Information Technology (HIT) recently sponsored an Institute of Medicine committee to evaluate how HIT use affects patient safety. In this paper, we propose the creation of a national EHR oversight program to provide dedicated surveillance of EHR-related safety hazards and to promote learning from identified errors, close calls, and adverse events. The program calls for data gathering, investigation/analysis and regulatory components. The first two functions will depend on institution-level EHR safety committees that will investigate all known EHR-related adverse events and near-misses and report them nationally using standardized methods. These committees should also perform routine safety self-assessments to proactively identify new risks. Nationally, we propose the long-term creation of a centralized, non-partisan board with an appropriate legal and regulatory infrastructure to ensure the safety of EHRs. We discuss the rationale of the proposed oversight program and its potential organizational components and functions. These include mechanisms for robust data collection and analyses of all safety concerns using multiple methods that extend beyond reporting; multidisciplinary investigation of selected high-risk safety events; and enhanced coordination with other national agencies in order to facilitate broad dissemination of hazards information. Implementation of this proposed infrastructure can facilitate identification of EHR-related adverse events and errors and potentially create a safer and more effective EHR-based health care delivery system. PMID:22080284

  16. 29 CFR 1915.89 - Control of hazardous energy (lockout/tags-plus).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... employee: (A) Sign a group tag (or a group tag equivalent), attach a personal identification device to a... group tag (or the group tag equivalent), remove the personal identification device, or perform a... safe exposure status of each authorized employee, and (b) signs a group tag (or a group tag equivalent...

  17. 29 CFR 1915.89 - Control of hazardous energy (lockout/tags-plus).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... employee: (A) Sign a group tag (or a group tag equivalent), attach a personal identification device to a... group tag (or the group tag equivalent), remove the personal identification device, or perform a... safe exposure status of each authorized employee, and (b) signs a group tag (or a group tag equivalent...

  18. 29 CFR 1915.89 - Control of hazardous energy (lockout/tags-plus).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... employee: (A) Sign a group tag (or a group tag equivalent), attach a personal identification device to a... group tag (or the group tag equivalent), remove the personal identification device, or perform a... safe exposure status of each authorized employee, and (b) signs a group tag (or a group tag equivalent...

  19. Instructions and Form for Hazardous Waste Generators, Transporters and Treatment, Storage and Disposal Facilities to Obtain an EPA Identification Number (EPA Form 8700-12/Site Identification Form)

    EPA Pesticide Factsheets

    This booklet is designed to help you determine if you are subject to requirements under the Resource Conservation and Recovery Act (RCRA) for notifying the U.S. Environmental Protection Agency (EPA) of your regulated waste activities.

  20. Rapid test for the detection of hazardous microbiological material

    NASA Astrophysics Data System (ADS)

    Mordmueller, Mario; Bohling, Christian; John, Andreas; Schade, Wolfgang

    2009-09-01

    After attacks with anthrax pathogens have been committed since 2001 all over the world the fast detection and determination of biological samples has attracted interest. A very promising method for a rapid test is Laser Induced Breakdown Spectroscopy (LIBS). LIBS is an optical method which uses time-resolved or time-integrated spectral analysis of optical plasma emission after pulsed laser excitation. Even though LIBS is well established for the determination of metals and other inorganic materials the analysis of microbiological organisms is difficult due to their very similar stoichiometric composition. To analyze similar LIBS-spectra computer assisted chemometrics is a very useful approach. In this paper we report on first results of developing a compact and fully automated rapid test for the detection of hazardous microbiological material. Experiments have been carried out with two setups: A bulky one which is composed of standard laboratory components and a compact one consisting of miniaturized industrial components. Both setups work at an excitation wavelength of λ=1064nm (Nd:YAG). Data analysis is done by Principal Component Analysis (PCA) with an adjacent neural network for fully automated sample identification.

  1. Development of methodologies for identification and quantification of hazardous air pollutants from turbine engine emissions.

    PubMed

    Anneken, David; Striebich, Richard; DeWitt, Matthew J; Klingshirn, Christopher; Corporan, Edwin

    2015-03-01

    Aircraft turbine engines are a significant source of particulate matter (PM) and gaseous emissions in the vicinity of airports and military installations. Hazardous air pollutants (HAPs) (e.g., formaldehyde, benzene, naphthalene and other compounds) associated with aircraft emissions are an environmental concern both in flight and at ground level. Therefore, effective sampling, identification, and accurate measurement of these trace species are important to assess their environmental impact. This effort evaluates two established ambient air sampling and analysis methods, U.S. Environmental Protection Agency (EPA) Method TO-11A and National Institute for Occupational Safety and Health (NIOSH) Method 1501, for potential use to quantify HAPs from aircraft turbine engines. The techniques were used to perform analysis of the exhaust from a T63 turboshaft engine, and were examined using certified gas standards transferred through the heated sampling systems used for engine exhaust gaseous emissions measurements. Test results show that the EPA Method TO-11A (for aldehydes) and NIOSH Method 1501 (for semivolatile hydrocarbons) were effective techniques for the sampling and analysis of most HAPs of interest. Both methods showed reasonable extraction efficiencies of HAP species from the sorbent tubes, with the exception of acrolein, styrene, and phenol, which were not well quantified. Formaldehyde measurements using dinitrophenylhydrazine (DNPH) tubes (EPA method TO-11A) were accurate for gas-phase standards, and compared favorably to measurements using gas-phase Fourier-transform infrared (FTIR) spectroscopy. In general, these two standard methodologies proved to be suitable techniques for field measurement of turbine engine HAPs within a reasonable (5-10 minutes) sampling period. Details of the tests, the analysis methods, calibration procedures, and results from the gas standards and T63 engine tested using a conventional JP-8 jet fuel are provided. HAPs from aviation-related sources are important because of their adverse health and environmental impacts in and around airports and flight lines. Simpler, more convenient techniques to measure the important HAPs, especially aldehydes and volatile organic HAPs, are needed to provide information about their occurrence and assist in the development of engines that emit fewer harmful emissions.

  2. Comparative Coastal Risk Index (CCRI): A multidisciplinary risk index for Latin America and the Caribbean

    PubMed Central

    Reguero, Borja G.; Zamora, Ana R.; Losada, Iñigo J.; Méndez, Fernando J.

    2017-01-01

    As the world’s population grows to a projected 11.2 billion by 2100, the number of people living in low-lying areas exposed to coastal hazards is projected to increase. Critical infrastructure and valuable assets continue to be placed in vulnerable areas, and in recent years, millions of people have been displaced by natural hazards. Impacts from coastal hazards depend on the number of people, value of assets, and presence of critical resources in harm’s way. Risks related to natural hazards are determined by a complex interaction between physical hazards, the vulnerability of a society or social-ecological system and its exposure to such hazards. Moreover, these risks are amplified by challenging socioeconomic dynamics, including poorly planned urban development, income inequality, and poverty. This study employs a combination of machine learning clustering techniques (Self Organizing Maps and K-Means) and a spatial index, to assess coastal risks in Latin America and the Caribbean (LAC) on a comparative scale. The proposed method meets multiple objectives, including the identification of hotspots and key drivers of coastal risk, and the ability to process large-volume multidimensional and multivariate datasets, effectively reducing sixteen variables related to coastal hazards, geographic exposure, and socioeconomic vulnerability, into a single index. Our results demonstrate that in LAC, more than 500,000 people live in areas where coastal hazards, exposure (of people, assets and ecosystems) and poverty converge, creating the ideal conditions for a perfect storm. Hotspot locations of coastal risk, identified by the proposed Comparative Coastal Risk Index (CCRI), contain more than 300,00 people and include: El Oro, Ecuador; Sinaloa, Mexico; Usulutan, El Salvador; and Chiapas, Mexico. Our results provide important insights into potential adaptation alternatives that could reduce the impacts of future hazards. Effective adaptation options must not only focus on developing coastal defenses, but also on improving practices and policies related to urban development, agricultural land use, and conservation, as well as ameliorating socioeconomic conditions. PMID:29095841

  3. Comparative Coastal Risk Index (CCRI): A multidisciplinary risk index for Latin America and the Caribbean.

    PubMed

    Calil, Juliano; Reguero, Borja G; Zamora, Ana R; Losada, Iñigo J; Méndez, Fernando J

    2017-01-01

    As the world's population grows to a projected 11.2 billion by 2100, the number of people living in low-lying areas exposed to coastal hazards is projected to increase. Critical infrastructure and valuable assets continue to be placed in vulnerable areas, and in recent years, millions of people have been displaced by natural hazards. Impacts from coastal hazards depend on the number of people, value of assets, and presence of critical resources in harm's way. Risks related to natural hazards are determined by a complex interaction between physical hazards, the vulnerability of a society or social-ecological system and its exposure to such hazards. Moreover, these risks are amplified by challenging socioeconomic dynamics, including poorly planned urban development, income inequality, and poverty. This study employs a combination of machine learning clustering techniques (Self Organizing Maps and K-Means) and a spatial index, to assess coastal risks in Latin America and the Caribbean (LAC) on a comparative scale. The proposed method meets multiple objectives, including the identification of hotspots and key drivers of coastal risk, and the ability to process large-volume multidimensional and multivariate datasets, effectively reducing sixteen variables related to coastal hazards, geographic exposure, and socioeconomic vulnerability, into a single index. Our results demonstrate that in LAC, more than 500,000 people live in areas where coastal hazards, exposure (of people, assets and ecosystems) and poverty converge, creating the ideal conditions for a perfect storm. Hotspot locations of coastal risk, identified by the proposed Comparative Coastal Risk Index (CCRI), contain more than 300,00 people and include: El Oro, Ecuador; Sinaloa, Mexico; Usulutan, El Salvador; and Chiapas, Mexico. Our results provide important insights into potential adaptation alternatives that could reduce the impacts of future hazards. Effective adaptation options must not only focus on developing coastal defenses, but also on improving practices and policies related to urban development, agricultural land use, and conservation, as well as ameliorating socioeconomic conditions.

  4. 48 CFR 223.303 - Contract clause.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material Identification and Material...

  5. 48 CFR 3023.303 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ACQUISITION REGULATION (HSAR) SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material Identification and...

  6. Signal transduction profile of chemical sensitisers in dendritic cells: An endpoint to be included in a cell-based in vitro alternative approach to hazard identification?

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Neves, Bruno Miguel; Centro de Neurociencias e Biologia Celular, Universidade de Coimbra, Coimbra 3004-517; Goncalo, Margarida

    2011-01-15

    The development of non-animal testing methods for the assessment of skin sensitisation potential is an urgent challenge within the framework of existing and forthcoming legislation. Efforts have been made to replace current animal tests, but so far no alternative methods have been developed. It is widely recognised that alternatives to animal testing cannot be accomplished with a single approach, but rather will require the integration of results obtained from different in vitro and in silico assays. The argument subjacent to the development of in vitro dendritic cell (DC)-based assays is that sensitiser-induced changes in the DC phenotype can be differentiatedmore » from those induced by irritants. This assumption is derived from the unique capacity of DC to convert environmental signals encountered at the skin into a receptor expression pattern (MHC class II molecules, co-stimulatory molecules, chemokine receptors) and a soluble mediator release profile that will stimulate T lymphocytes. Since signal transduction cascades precede changes in surface marker expression and cytokine/chemokine secretion, these phenotypic modifications are a consequence of a signal transduction profile that is specifically triggered by sensitisers and not by irritants. A limited number of studies have addressed this subject and the present review attempts to summarise and highlight all of the signalling pathways modulated by skin sensitisers and irritants. Furthermore, we conclude this review by focusing on the most promising strategies suitable for inclusion into a cell-based in vitro alternative approach to hazard identification.« less

  7. Method, system and apparatus for monitoring and adjusting the quality of indoor air

    DOEpatents

    Hartenstein, Steven D.; Tremblay, Paul L.; Fryer, Michael O.; Hohorst, Frederick A.

    2004-03-23

    A system, method and apparatus is provided for monitoring and adjusting the quality of indoor air. A sensor array senses an air sample from the indoor air and analyzes the air sample to obtain signatures representative of contaminants in the air sample. When the level or type of contaminant poses a threat or hazard to the occupants, the present invention takes corrective actions which may include introducing additional fresh air. The corrective actions taken are intended to promote overall health of personnel, prevent personnel from being overexposed to hazardous contaminants and minimize the cost of operating the HVAC system. The identification of the contaminants is performed by comparing the signatures provided by the sensor array with a database of known signatures. Upon identification, the system takes corrective actions based on the level of contaminant present. The present invention is capable of learning the identity of previously unknown contaminants, which increases its ability to identify contaminants in the future. Indoor air quality is assured by monitoring the contaminants not only in the indoor air, but also in the outdoor air and the air which is to be recirculated. The present invention is easily adaptable to new and existing HVAC systems. In sum, the present invention is able to monitor and adjust the quality of indoor air in real time by sensing the level and type of contaminants present in indoor air, outdoor and recirculated air, providing an intelligent decision about the quality of the air, and minimizing the cost of operating an HVAC system.

  8. Laser Scanning Systems and Techniques in Rockfall Source Identification and Risk Assessment: A Critical Review

    NASA Astrophysics Data System (ADS)

    Fanos, Ali Mutar; Pradhan, Biswajeet

    2018-04-01

    Rockfall poses risk to people, their properties and to transportation ways in mountainous and hilly regions. This catastrophe shows various characteristics such as vast distribution, sudden occurrence, variable magnitude, strong fatalness and randomicity. Therefore, prediction of rockfall phenomenon both spatially and temporally is a challenging task. Digital Terrain model (DTM) is one of the most significant elements in rockfall source identification and risk assessment. Light detection and ranging (LiDAR) is the most advanced effective technique to derive high-resolution and accurate DTM. This paper presents a critical overview of rockfall phenomenon (definition, triggering factors, motion modes and modeling) and LiDAR technique in terms of data pre-processing, DTM generation and the factors that can be obtained from this technique for rockfall source identification and risk assessment. It also reviews the existing methods that are utilized for the evaluation of the rockfall trajectories and their characteristics (frequency, velocity, bouncing height and kinetic energy), probability, susceptibility, hazard and risk. Detail consideration is given on quantitative methodologies in addition to the qualitative ones. Various methods are demonstrated with respect to their application scales (local and regional). Additionally, attention is given to the latest improvement, particularly including the consideration of the intensity of the phenomena and the magnitude of the events at chosen sites.

  9. 75 FR 51678 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Final Exclusion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ... present a disproportionate risk to children. The basis for this belief is that the Agency used the DRAS...: ``Under civil and criminal penalty of law for the making or submission of false or fraudulent statements... determined by EPA in its sole discretion to be false, inaccurate or incomplete, and upon conveyance of this...

  10. Man-rating of a launch vehicle

    NASA Astrophysics Data System (ADS)

    Soeffker, D.

    Analysis techniques for hazard identification, classification, and control, developed for Spacelab, are presented. Hazards were classified as catastrophic (leading to crew or vehicle loss) critical (could lead to serious injury or damage) and controlled (counteracted by design). All nonmetallic materials were rated for flammability in oxygen enriched atmospheres, toxic offgassing, and odor. Any element with less than 200 mission capability was rated life limited.

  11. The Development of an Earthquake Preparedness Plan for a Child Care Center in a Geologically Hazardous Region.

    ERIC Educational Resources Information Center

    Wokurka, Linda

    The director of a child care center at a community college in California developed an earthquake preparedness plan for the center which met state and local requirements for earthquake preparedness at schools. The plan consisted of: (1) the identification and reduction of nonstructural hazards in classrooms, office, and staff rooms; (2) storage of…

  12. RCRA Refresher Self-Study, Course 28582

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Simpson, Lewis Edward

    Federal and state regulations require hazardous and mixed waste facility workers at treatment and storage facilities (TSFs) and <90-day accumulation areas to be trained in hazardous and mixed waste management. This course will refamiliarize and update <90-day accumulation area workers, TSF workers, and supervisors of TSF workers regarding waste identification, pollution prevention, storage area requirements, emergency response procedures, and record-keeping requirements.

  13. RCRA Personnel Training, Course 7488

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Simpson, Lewis Edward

    Federal and state regulations require hazardous and mixed waste facility workers at treatment and storage facilities (TSFs) and <90-day accumulation areas to be trained in hazardous and mixed waste management. This course will refamiliarize and update <90-day accumulation area workers, TSF workers, and supervisors of TSF workers regarding waste identification, pollution prevention, storage area requirements, emergency response procedures, and record-keeping requirements.

  14. 77 FR 41720 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Proposed Exclusion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-16

    ... delist? B. How does IBM generate the waste? C. How did IBM sample and analyze the petitioned waste? D..., thickened/conditioned, and pressed to generate the F006 waste stream. C. How did IBM sample and analyze the... the volatiles and semi-volatiles samples were non- detect. E. How did EPA evaluate the risk of...

  15. 75 FR 60632 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste; Direct Final Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-01

    ... action is EPA approving? B. Why is EPA approving this delisting? C. How will Beaumont Refinery manage the wastes, if it is delisted? D. When would the delisting exclusion be finalized? E. How would this action... petition? D. What were the results of Beaumont Refinery's analysis? E. How did EPA evaluate the risk of...

  16. Does Workplace Social Capital Associate with Hazardous Drinking Among Chinese Rural-Urban Migrant Workers?

    PubMed Central

    Gao, Junling; Weaver, Scott R.; Fua, Hua; Pan, Zhigang

    2014-01-01

    Background The present study sought to investigate the associations between workplace social capital and hazardous drinking (HD) among Chinese rural-urban migrant workers (RUMW). Methods A cross sectional study with a multi-stage stratified sampling procedure was conducted in Shanghai during July 2012 to January 2013. In total, 5,318 RUMWs from 77 workplaces were involved. Work-place social capital was assessed using a validated and psychometrically tested eight-item measure. The Chinese version of Alcohol Use Disorders Identification Test (AUDIT) was used to assess hazardous drinking. Control variables included gender, age, marital status, education level, salary, and current smoking. Multilevel logistic regression analysis was conducted to test whether individual- and workplace-level social capital was associated with hazardous drinking. Results Overall, the prevalence of HD was 10.6%. After controlling for individual-level socio-demographic and lifestyle variables, compared to workers in the highest quartile of individual-level social capital, the odds of HD for workers in the three bottom quartiles were 1.13(95%CI: 1.04–1.23), 1.17(95%CI: 1.05–1.56) and 1.26(95%CI: 1.13–1.72), respectively. However, contrary to hypothesis, there was no relationship between workplace-level social capital and hazardous drinking. Conclusions Higher individual-level social capital may protect against HD among Chinese RUMWs. Interventions to build individual social capital among RUMWs in China may help reduce HD among this population. PMID:25502013

  17. Toward Identifying the Next Generation of Superfund and Hazardous Waste Site Contaminants

    PubMed Central

    Ela, Wendell P.; Sedlak, David L.; Barlaz, Morton A.; Henry, Heather F.; Muir, Derek C.G.; Swackhamer, Deborah L.; Weber, Eric J.; Arnold, Robert G.; Ferguson, P. Lee; Field, Jennifer A.; Furlong, Edward T.; Giesy, John P.; Halden, Rolf U.; Henry, Tala; Hites, Ronald A.; Hornbuckle, Keri C.; Howard, Philip H.; Luthy, Richard G.; Meyer, Anita K.; Sáez, A. Eduardo; vom Saal, Frederick S.; Vulpe, Chris D.; Wiesner, Mark R.

    2011-01-01

    Background This commentary evolved from a workshop sponsored by the National Institute of Environmental Health Sciences titled “Superfund Contaminants: The Next Generation” held in Tucson, Arizona, in August 2009. All the authors were workshop participants. Objectives Our aim was to initiate a dynamic, adaptable process for identifying contaminants of emerging concern (CECs) that are likely to be found in future hazardous waste sites, and to identify the gaps in primary research that cause uncertainty in determining future hazardous waste site contaminants. Discussion Superfund-relevant CECs can be characterized by specific attributes: They are persistent, bioaccumulative, toxic, occur in large quantities, and have localized accumulation with a likelihood of exposure. Although still under development and incompletely applied, methods to quantify these attributes can assist in winnowing down the list of candidates from the universe of potential CECs. Unfortunately, significant research gaps exist in detection and quantification, environmental fate and transport, health and risk assessment, and site exploration and remediation for CECs. Addressing these gaps is prerequisite to a preventive approach to generating and managing hazardous waste sites. Conclusions A need exists for a carefully considered and orchestrated expansion of programmatic and research efforts to identify, evaluate, and manage CECs of hazardous waste site relevance, including developing an evolving list of priority CECs, intensifying the identification and monitoring of likely sites of present or future accumulation of CECs, and implementing efforts that focus on a holistic approach to prevention. PMID:21205582

  18. Prospective Changes in Alcohol Use Among Hazardous Drinkers in the Absence of Treatment

    PubMed Central

    Dearing, Ronda L.; Witkiewitz, Katie; Connors, Gerard J.; Walitzer, Kimberly S.

    2012-01-01

    Gaining a better understanding of the natural course of hazardous alcohol consumption could inform the development of brief interventions to encourage self-change. In the current study, hazardous drinkers (based on Alcohol Use Disorders Identification Test score) were recruited using advertisements to participate in a 2-year multi-wave prospective study. Participants (N = 206) provided self-reports every six months during the study, including reports of daily alcohol consumption. The current investigation focuses on self-initiated change in participants’ frequency of heavy drinking days (i.e., ≥ 5/4 drinks per day for men/women), as predicted by a number of demographic (e.g., age) and psychosocial (e.g., guilt-proneness) variables. Latent growth curve models of the change in percent heavy drinking days over the 2-year period provided an excellent fit to the observed data and indicated a significant decline in percent heavy drinking days over time. Reductions in heavy drinking frequency were predicted by younger age and higher guilt-proneness. The identification of these predictors of reductions in heavy drinking frequency provides information to guide future work investigating self-change among hazardous drinkers. PMID:22612252

  19. Prospective changes in alcohol use among hazardous drinkers in the absence of treatment.

    PubMed

    Dearing, Ronda L; Witkiewitz, Katie; Connors, Gerard J; Walitzer, Kimberly S

    2013-03-01

    Gaining a better understanding of the natural course of hazardous alcohol consumption could inform the development of brief interventions to encourage self-change. In the current study, hazardous drinkers (based on Alcohol Use Disorders Identification Test score) were recruited using advertisements to participate in a 2-year multiwave prospective study. Participants (n = 206) provided self-reports every six months during the study, including reports of daily alcohol consumption. The current investigation focuses on self-initiated change in participants' frequency of heavy drinking days (i.e., ≥ 5/4 drinks per day for men/women), as predicted by a number of demographic (e.g., age) and psychosocial (e.g., guilt-proneness) variables. Latent growth curve models of the change in percent heavy drinking days over the 2-year period provided an excellent fit to the observed data and indicated a significant decline in percent heavy drinking days over time. Reductions in heavy drinking frequency were predicted by younger age and higher guilt-proneness. The identification of these predictors of reductions in heavy drinking frequency provides information to guide future work investigating self-change among hazardous drinkers. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

  20. Precursors of dangerous substances formed in the loss of control of chemical systems.

    PubMed

    Cozzani, V; Zanelli, S

    1999-03-01

    Article 2 of Directive 96/82/EC on the control of major accident hazards caused by dangerous substances requires to consider also the hazards due to the dangerous substances "which it is believed may be generated during loss of control of an industrial chemical process", although no generally accepted guidelines are available for the identification of these substances. In the present study, the accidents involving the unwanted formation of dangerous substances as a consequence of the loss of control of chemical systems were investigated. A specifically developed database was used, containing data on more than 400 of these accidents and on the substances involved. The hazardous substances formed in the accidents and the precursors of these substances were identified. The influence of accident characteristics on the substances formed was investigated. In the context of the application of Directive 96/82/EC, an accident severity index and a hazard rating of the precursors of dangerous substances formed in the accidents were proposed. A lumping approach was used in order to develop schemes for the preliminary identification of substances that may be formed in the loss of control of chemical system. The results of accident analysis were used to test the schemes developed.

  1. Panel 2: anticipatory risk assessment: identifying, assessing, and mitigating exposure risks before they occur.

    PubMed

    Guidotti, Tee L; Pacha, Laura

    2011-07-01

    Health threats place the military mission and deployed service members at risk. A commander's focus is on preventing acute health risks, such as diarrhea, because these quickly compromise the mission. However, in recent conflicts chronic and long-term illness risks have emerged as concerns. Department of Defense and Joint Chiefs of Staff mandates require documentation of exposures and environmental conditions to reconstruct exposures and evaluate future health risks. Current processes for identifying and assessing hazards, including identification and assessment before deployment and in time to take action to prevent or reduce exposures, when followed, are generally adequate for known hazards. Identifying and addressing novel, unexpected risks remain challenges. Armed conflicts are associated with rapidly changing conditions, making ongoing hazard identification and assessment difficult. Therefore, surveillance of the environment for hazards and surveillance of personnel for morbidity must be practiced at all times. Communication of risk information to decision makers is critical but problematic. Preventive Medicine (PM) personnel should take responsibility for communicating this information to non-PM military medical people and to military commanders. Communication of risks identified and lessons learned between PM personnel of different military units is extremely important when one military unit replaces another in a deployed environment.

  2. 48 CFR 223.370-4 - Procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material Identification and Material...

  3. 48 CFR 223.370-2 - Definition.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material Identification and Material...

  4. Use of a remotely piloted aircraft system for hazard assessment in a rocky mining area (Lucca, Italy)

    NASA Astrophysics Data System (ADS)

    Salvini, Riccardo; Mastrorocco, Giovanni; Esposito, Giuseppe; Di Bartolo, Silvia; Coggan, John; Vanneschi, Claudio

    2018-01-01

    The use of remote sensing techniques is now common practice in different working environments, including engineering geology. Moreover, in recent years the development of structure from motion (SfM) methods, together with rapid technological improvement, has allowed the widespread use of cost-effective remotely piloted aircraft systems (RPAS) for acquiring detailed and accurate geometrical information even in evolving environments, such as mining contexts. Indeed, the acquisition of remotely sensed data from hazardous areas provides accurate 3-D models and high-resolution orthophotos minimizing the risk for operators. The quality and quantity of the data obtainable from RPAS surveys can then be used for inspection of mining areas, audit of mining design, rock mass characterizations, stability analysis investigations and monitoring activities. Despite the widespread use of RPAS, its potential and limitations still have to be fully understood.In this paper a case study is shown where a RPAS was used for the engineering geological investigation of a closed marble mine area in Italy; direct ground-based techniques could not be applied for safety reasons. In view of the re-activation of mining operations, high-resolution images taken from different positions and heights were acquired and processed using SfM techniques to obtain an accurate and detailed 3-D model of the area. The geometrical and radiometrical information was subsequently used for a deterministic rock mass characterization, which led to the identification of two large marble blocks that pose a potential significant hazard issue for the future workforce. A preliminary stability analysis, with a focus on investigating the contribution of potential rock bridges, was then performed in order to demonstrate the potential use of RPAS information in engineering geological contexts for geohazard identification, awareness and reduction.

  5. 49 CFR 390.19 - Motor carrier, hazardous material shipper, and intermodal equipment provider identification reports.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... file a Motor Carrier Identification Report, Form MCS-150. (2) A motor carrier conducting operations in... this section at the following times: (1) Before it begins operations; and (2) Every 24 months, according to the following schedule: USDOT numberending in Must file by last day of 1 January. 2 February. 3...

  6. 49 CFR 390.19 - Motor carrier, hazardous material shipper, and intermodal equipment provider identification reports.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... file a Motor Carrier Identification Report, Form MCS-150. (2) A motor carrier conducting operations in... this section at the following times: (1) Before it begins operations; and (2) Every 24 months, according to the following schedule: USDOT numberending in Must file by last day of 1 January. 2 February. 3...

  7. 76 FR 68193 - Notice of the Revised Priority List of Hazardous Substances That Will Be the Subject of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ... assessments and from site-file data packages used to develop the public health assessments. Since the... toxicological profile subject, as well as a candidate for identification of priority data needs. In addition to... toxicological profile prepared by ATSDR and, subsequently, a candidate for the identification of priority data...

  8. 48 CFR 223.302 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material Identification and Material Safety Data 223.302...

  9. 48 CFR 223.370-5 - Contract clauses.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ..., DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material Identification and Material...

  10. How Prepared Are Medical and Nursing Students to Identify Common Hazards in the Intensive Care Unit?

    PubMed

    Clay, Alison S; Chudgar, Saumil M; Turner, Kathleen M; Vaughn, Jacqueline; Knudsen, Nancy W; Farnan, Jeanne M; Arora, Vineet M; Molloy, Margory A

    2017-04-01

    Care in the hospital is hazardous. Harm in the hospital may prolong hospitalization, increase suffering, result in death, and increase costs of care. Although the interprofessional team is critical to eliminating hazards that may result in adverse events to patients, professional students' formal education may not prepare them adequately for this role. To determine if medical and nursing students can identify hazards of hospitalization that could result in harm to patients and to detect differences between professions in the types of hazards identified. Mixed-methods observational study of graduating nursing (n = 51) and medical (n = 93) students who completed two "Room of Horrors" simulations to identify patient safety hazards. Qualitative analysis was used to extract themes from students' written hazard descriptions. Fisher's exact test was used to determine differences in frequency of hazards identified between groups. Identification of hazards by students was low: 66% did not identify missing personal protective equipment for a patient on contact isolation, and 58% did not identify a medication administration error (medication hanging for a patient with similar name). Interprofessional differences existed in how hazards were identified: medical students noted that restraints were not indicated (73 vs. 2%, P < 0.001), whereas nursing students noted that there was no order for the restraints (58.5 vs. 0%, P < 0.0001). Nursing students discovered more issues with malfunctioning or incorrectly used equipment than medical students. Teams performed better than individuals, especially for hazards in the second simulation that were similar to those in the first: need to replace a central line with erythema (73% teams identified) versus need to replace a peripheral intravenous line (10% individuals, P < 0.0001). Nevertheless, teams of students missed many intensive care unit-specific hazards: 54% failed to identify the presence of pressure ulcers; 85% did not notice high tidal volumes on the ventilator; and 90% did not identify the absence of missing spontaneous awakening/breathing trials and absent stress ulcer prophylaxis. Graduating nursing and medical students missed several hazards of hospitalization, especially those related to the intensive care unit. Orientation for residents and new nurses should include education on hospitalization hazards. Ideally, this orientation should be interprofessional to allow appreciation for each other's roles and responsibilities.

  11. Hazards on Hazards, Ensuring Spacecraft Safety While Sampling Asteroid Surface Materials

    NASA Astrophysics Data System (ADS)

    Johnson, C. A.; DellaGiustina, D. N.

    2016-12-01

    The near-Earth object Bennu is a carbonaceous asteroid that is a remnant from the earliest stages of the solar-system formation. It is also a potentially hazardous asteroid with a relatively high probability of impacting Earth late in the 22nd century. While the primary focus of the NASA funded OSIRIS-REx mission is the return of pristine organic material from the asteroid's surface, information about Bennu's physical and chemical properties gleaned throughout operations will be critical for a possible future impact mitigation mission. In order to ensure a regolith sample can be successfully acquired, the sample site and surrounding area must be thoroughly assessed for any potential hazards to the spacecraft. The OSIRIS-REx Image Processing Working Group has been tasked with generating global and site-specific hazard maps using mosaics and a trio of fea­­­ture identification techniques. These techniques include expert-lead manual classification, internet-based amateur classification using the citizen science platform CosmoQuest, and automated classification using machine learning and computer vision tools. Because proximity operations around Bennu do not begin until the end of 2018, we have an opportunity to test t­­­he performance of our software on analogue surfaces of other asteroids from previous NASA and other space agencies missions. The entire pipeline from image processing and mosaicking to hazard identification, analysis and mapping will be performed on asteroids of varying size, shape and surface morphology. As a result, upon arrival at Bennu, we will have the software and processes in place to quickly and confidently produce the hazard maps needed to ensure the success of our mission.

  12. 48 CFR 23.303 - Contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material Identification and Material Safety Data 23.303 Contract clause...

  13. 48 CFR 223.370-3 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material Identification and Material Safety Data 223.370...

  14. 48 CFR 1223.303 - Contract clause.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material Identification and Material Safety Data 1223.303 Contract clause...

  15. 48 CFR 23.303 - Contract clause.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material Identification and Material Safety Data 23.303 Contract clause...

  16. 48 CFR 223.370-1 - Scope.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... DEFENSE SOCIOECONOMIC PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material Identification and Material Safety Data 223.370...

  17. Regional danger assessment of Debris flow and its engineering mitigation practice in Sichuan-Tibet highway

    NASA Astrophysics Data System (ADS)

    Su, Pengcheng; Sun, Zhengchao; li, Yong

    2017-04-01

    Luding-Kangding highway cross the eastern edge of Qinghai-Tibet Plateau where belong to the most deep canyon area of plateau and mountains in western Sichuan with high mountain and steep slope. This area belongs to the intersection among Xianshuihe, Longmenshan and Anninghe fault zones which are best known in Sichuan province. In the region, seismic intensity is with high frequency and strength, new tectonic movement is strong, rock is cracked, there are much loose solid materials. Debris flow disaster is well developed under the multiple effects of the earthquake, strong rainfall and human activity which poses a great threat to the local people's life and property security. So this paper chooses Kangding and LuDing as the study area to do the debris flow hazard assessment through the in-depth analysis of development characteristics and formation mechanism of debris flow. Which can provide important evidence for local disaster assessment and early warning forecast. It also has the important scientific significance and practical value to safeguard the people's life and property safety and the security implementation of the national major project. In this article, occurrence mechanism of debris flow disasters in the study area is explored, factor of evaluation with high impact to debris flow hazards is identified, the database of initial evaluation factors is made by the evaluation unit of basin. The factors with high impact to hazards occurrence are selected by using the stepwise regression method of logistic regression model, at the same time the factors with low impact are eliminated, then the hazard evaluation factor system of debris flow is determined in the study area. Then every factors of evaluation factor system are quantified, and the weights of all evaluation factors are determined by using the analysis of stepwise regression. The debris flows hazard assessment and regionalization of all the whole study area are achieved eventually after establishing the hazard assessment model. In this paper, regional debris flows hazard assessment method with strong universality and reliable evaluation result is presented. The whole study area is divided into 1674 units by automatically extracting and artificial identification, and then 11 factors are selected as the initial assessment factors of debris flow hazard assessment in the study area. The factors of the evaluation index system are quantified using the method of standardized watershed unit amount ratio. The relationship between debris flow occurrence and each evaluation factor is simulated using logistic regression model. The weights of evaluation factors are determined, and the model of debris flows hazard assessment is established in the study area. Danger assessment result of debris flow was applied in line optimization and engineering disaster reduction of Sichuan-Tibet highway (section of Luding-Kangding).

  18. DOE Office of Scientific and Technical Information (OSTI.GOV)

    R. Camp

    Over the past four years, the Electrical Safety Program at PPPL has evolved in addressing changing regulatory requirements and lessons learned from accident events, particularly in regards to arc flash hazards and implementing NFPA 70E requirements. This presentation will discuss PPPL's approaches to the areas of electrical hazards evaluation, both shock and arc flash; engineered solutions for hazards mitigation such as remote racking of medium voltage breakers, operational changes for hazards avoidance, targeted personnel training and hazard appropriate personal protective equipment. Practical solutions for nominal voltage identification and zero voltage checks for lockout/tagout will also be covered. Finally, we willmore » review the value of a comprehensive electrical drawing program, employee attitudes expressed as a personal safety work ethic, integrated safety management, and sustained management support for continuous safety improvement.« less

  19. Towards identifying the next generation of superfund and hazardous waste site contaminants

    USGS Publications Warehouse

    Ela, Wendell P.; Sedlak, David L.; Barlaz, Morton A.; Henry, Heather F.; Muir, Derek C.G.; Swackhamer, Deborah L.; Weber, Eric J.; Arnold, Robert G.; Ferguson, P. Lee; Field, Jennifer A.; Furlong, Edward T.; Giesy, John P.; Halden, Rolf U.; Henry, Tala; Hites, Ronald A.; Hornbuckle, Keri C.; Howard, Philip H.; Luthy, Richard G.; Meyer, Anita K.; Saez, A. Eduardo; vom Saal, Frederick S.; Vulpe, Chris D.; Wiesner, Mark R.

    2011-01-01

    Conclusions A need exists for a carefully considered and orchestrated expansion of programmatic and research efforts to identify, evaluate, and manage CECs of hazardous waste site relevance, including developing an evolving list of priority CECs, intensifying the identification and monitoring of likely sites of present or future accumulation of CECs, and implementing efforts that focus on a holistic approach to prevention.

  20. Identification of Critical Biological Parameters Affecting Gastrointestinal Absorption

    DTIC Science & Technology

    1990-01-01

    invention that may in any way be related thereto. Please do not request copies of this report from the Harry G. Armstrong Aerospace Medical Research...BALLINGER, Lt Col, USAF, BSC Chief, Toxic Hazards Division Harry G. Armstrong Aerospace Medical Research Laboratory UNCLASSIFIED SECURITY CLASSIFICATION OF...involved in a very large task of hazard management through its Installation Restoration Program. The pioneering efforts of the Armstrong Aerospace

  1. Quantitative Microbial Risk Assessment for Clostridium perfringens in Natural and Processed Cheeses

    PubMed Central

    Lee, Heeyoung; Lee, Soomin; Kim, Sejeong; Lee, Jeeyeon; Ha, Jimyeong; Yoon, Yohan

    2016-01-01

    This study evaluated the risk of Clostridium perfringens (C. perfringens) foodborne illness from natural and processed cheeses. Microbial risk assessment in this study was conducted according to four steps: hazard identification, hazard characterization, exposure assessment, and risk characterization. The hazard identification of C. perfringens on cheese was identified through literature, and dose response models were utilized for hazard characterization of the pathogen. For exposure assessment, the prevalence of C. perfringens, storage temperatures, storage time, and annual amounts of cheese consumption were surveyed. Eventually, a simulation model was developed using the collected data and the simulation result was used to estimate the probability of C. perfringens foodborne illness by cheese consumption with @RISK. C. perfringens was determined to be low risk on cheese based on hazard identification, and the exponential model (r = 1.82×10−11) was deemed appropriate for hazard characterization. Annual amounts of natural and processed cheese consumption were 12.40±19.43 g and 19.46±14.39 g, respectively. Since the contamination levels of C. perfringens on natural (0.30 Log CFU/g) and processed cheeses (0.45 Log CFU/g) were below the detection limit, the initial contamination levels of natural and processed cheeses were estimated by beta distribution (α1 = 1, α2 = 91; α1 = 1, α2 = 309)×uniform distribution (a = 0, b = 2; a = 0, b = 2.8) to be −2.35 and −2.73 Log CFU/g, respectively. Moreover, no growth of C. perfringens was observed for exposure assessment to simulated conditions of distribution and storage. These data were used for risk characterization by a simulation model, and the mean values of the probability of C. perfringens foodborne illness by cheese consumption per person per day for natural and processed cheeses were 9.57×10−14 and 3.58×10−14, respectively. These results indicate that probability of C. perfringens foodborne illness by consumption cheese is low, and it can be used to establish microbial criteria for C. perfringens on natural and processed cheeses. PMID:26954204

  2. Pressure vessel burst test program - Initial program paper

    NASA Technical Reports Server (NTRS)

    Cain, Maurice R.; Sharp, Douglas E.; Coleman, Michael D.; Webb, Bobby L.

    1990-01-01

    The current status of a pressure vessel burst test program, aimed at the study of the blast waves and fragmentation characteristics of ruptured gas-filled pressure vessels, is reported. The program includes a series of test plans, each involving multiple bursts with burst pressures ranging to 7500 psig. The discussion covers the identification of concerns and hazards, application of the data generated, and a brief review of the current methods for assessing vessel safety and burst parameters. Attention is also given to pretest activities, including completed vessel and facility/instrumentation preparation and results of completed preliminary burst tests.

  3. Communication path for extreme environments

    NASA Technical Reports Server (NTRS)

    Jorgensen, Charles C. (Inventor); Betts, Bradley J. (Inventor)

    2010-01-01

    Methods and systems for using one or more radio frequency identification devices (RFIDs), or other suitable signal transmitters and/or receivers, to provide a sensor information communication path, to provide location and/or spatial orientation information for an emergency service worker (ESW), to provide an ESW escape route, to indicate a direction from an ESW to an ES appliance, to provide updated information on a region or structure that presents an extreme environment (fire, hazardous fluid leak, underwater, nuclear, etc.) in which an ESW works, and to provide accumulated thermal load or thermal breakdown information on one or more locations in the region.

  4. Risk assessment for safety laboratories in Politeknik Negeri Medan

    NASA Astrophysics Data System (ADS)

    Viyata Sundawa, Bakti; Hutajulu, Elferida; Sirait, Regina; Banurea, Waldemar; Indrayadi; Mulyadi, Sangap

    2017-09-01

    International Labour Organization (ILO) estimated 2.34 million people die each year because accidents and diseases in workplace. It also impact to economic losses in some countries. It need to do safety and healthy in working environment especially in laboratory. Identification of potential hazards and risks must be done in Telecommunication Laboratory Politeknik Negeri Medan. Therefore, this study was assessed 5 of potential hazards and risks in our laboratory by Likert Scale. This object was divided into 2 assessment namely likelihood of hazards and severity of consequences. Collecting data is taken from questionnaire who involved 100 students at random academic level. The result showed The highest score is chemical hazards 73.2% in likelihood of hazards and electrical hazards 85% in severity of consequences. This condition is classified as “high” state. Big attention must be given to “high” state because it can help us to determine mitigate action.

  5. Quantitative risk assessment for skin sensitization: Success or failure?

    PubMed

    Kimber, Ian; Gerberick, G Frank; Basketter, David A

    2017-02-01

    Skin sensitization is unique in the world of toxicology. There is a combination of reliable, validated predictive test methods for identification of skin sensitizing chemicals, a clearly documented and transparent approach to risk assessment, and effective feedback from dermatology clinics around the world delivering evidence of the success or failure of the hazard identification/risk assessment/management process. Recent epidemics of contact allergy, particularly to preservatives, have raised questions of whether the safety/risk assessment process is working in an optimal manner (or indeed is working at all!). This review has as its focus skin sensitization quantitative risk assessment (QRA). The core toxicological principles of QRA are reviewed, and evidence of use and misuse examined. What becomes clear is that skin sensitization QRA will only function adequately if two essential criteria are met. The first is that QRA is applied rigourously, and the second is that potential exposure to the sensitizing substance is assessed adequately. This conclusion will come as no surprise to any toxicologist who appreciates the basic premise that "risk = hazard x exposure". Accordingly, use of skin sensitization QRA is encouraged, not least because the essential feedback from dermatology clinics can be used as a tool to refine QRA in situations where this risk assessment tool has not been properly used. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Occupational hazards to health of port workers.

    PubMed

    Wang, Yukun; Zhan, Shuifen; Liu, Yan; Li, Yan

    2017-12-01

    The aim of this article is to reduce the risk of occupational hazards and improve safety conditions by enhancing hazard knowledge and identification as well as improving safety behavior for freight port enterprises. In the article, occupational hazards to health and their prevention measures of freight port enterprises have been summarized through a lot of occupational health evaluation work, experience and understanding. Workers of freight port enterprises confront an equally wide variety of chemical, physical and psychological hazards in production technology, production environment and the course of labor. Such health hazards have been identified, the risks evaluated, the dangers to health notified and effective prevention measures which should be put in place to ensure the health of the port workers summarized. There is still a long way to go for the freight port enterprises to prevent and control the occupational hazards. Except for occupational hazards and their prevention measures, other factors that influence the health of port workers should also be paid attention to, such as age, work history, gender, contraindication and even the occurrence and development rules of occupational hazards in current production conditions.

  7. Predictors of hazardous drinking, tobacco smoking and physical inactivity in vocational school students

    PubMed Central

    2013-01-01

    Background Tobacco smoking, hazardous drinking and physical inactivity during adolescence are risk factors that are associated with poorer health in adulthood. The identification of subgroups of young people with a high prevalence of one or more of these risk factors allows an optimised allocation of preventive measures. This study aimed at investigating hazardous drinking, tobacco smoking and physical inactivity as well as their associations and demographic predictors in vocational school students. Methods Out of 57 contacted vocational schools in Switzerland, a total of 24 schools participated in a survey assessing gender, age, immigrant background, educational attainment and vocational field as well as the above mentioned health risk factors. Out of the 2659 students present in 177 included vocational school classes, 2647 (99.5%) completed the survey. Binary logistic regression analyses were conducted to investigate the demographic predictors of each health risk factor and a multinomial logistic regression analysis was conducted to investigate predictors of different risk factor combinations. Results Of the surveyed students, 79.4% showed at least one risk factor, 43.6% showed two or more and 9.6% showed all three health risk factors. Hazardous drinking was more prevalent in male, physical inactivity was more prevalent in female vocational school students. The proportion of students with low physical activity and tobacco smoking increased with increasing age. While the combination of hazardous drinking and tobacco smoking was higher in males, the other risk factor combinations were observed particularly among females. Conclusions Multiple risk factors were ascertained in a significant proportion of vocational school students. Specifically, tobacco smoking and hazardous drinking were coexistent. The study underlines the need for preventive measures in specific subpopulations of adolescents and young adults with lower educational level. PMID:23672294

  8. NEW TECHNOLOGY FOR CONDUCTING RADIATION HAZARD ASSESSMENTS: THE APPLICATION OF THE UNDERWATER RADIATION SPECTRAL IDENTIFICATION SYSTEM (URSIS) AT THE MASSACHUSETTS BAY INDUSTRIAL WASTE (SITE) (U.S.A.)

    EPA Science Inventory

    The Underwater Radiation Spectral Identification System (URSIS) is a portable spectrometer used for the in situ detection of radioactivity in the marine environment. This paper reports on the first time application of this technology to assess, in a preliminary manner, the potent...

  9. Dual-use applications of laser remote sensing to the military battlefield and environmental monitoring

    NASA Astrophysics Data System (ADS)

    Leonelli, Joseph

    1994-06-01

    For the past 20 years, the Department of Defense has sponsored investigations and studies on the use of laser remote sensing techniques and light detection and ranging (lidar) methods for the detection, identification, and tracking of toxic and hazardous battlefield materials. The same lidar methods used by NASA, EPA, and several industry research groups to detect and measure the movement and concentration of air pollution near urban centers have been applied to the national security problem of detecting chemical and biological warfare agents that might be used on the modern battlefield. Significant government investment in the technology base and laser technology has resulted in advanced hardware configurations that are now available for demonstration and evaluation for industrial and environmental monitoring.

  10. Characterization of Aspergillus species on Brazil nut from the Brazilian Amazonian region and development of a PCR assay for identification at the genus level

    PubMed Central

    2014-01-01

    Background Brazil nut is a protein-rich extractivist tree crop in the Amazon region. Fungal contamination of shells and kernel material frequently includes the presence of aflatoxigenic Aspergillus species from the section Flavi. Aflatoxins are polyketide secondary metabolites, which are hepatotoxic carcinogens in mammals. The objectives of this study were to identify Aspergillus species occurring on Brazil nut grown in different states in the Brazilian Amazon region and develop a specific PCR method for collective identification of member species of the genus Aspergillus. Results Polyphasic identification of 137 Aspergillus strains isolated from Brazil nut shell material from cooperatives across the Brazilian Amazon states of Acre, Amapá and Amazonas revealed five species, with Aspergillus section Flavi species A. nomius and A. flavus the most abundant. PCR primers ASP_GEN_MTSSU_F1 and ASP_GEN_MTSSU_R1 were designed for the genus Aspergillus, targeting a portion of the mitochondrial small subunit ribosomal RNA gene. Primer specificity was validated through both electronic PCR against target gene sequences at Genbank and in PCR reactions against DNA from Aspergillus species and other fungal genera common on Brazil nut. Collective differentiation of the observed section Flavi species A. flavus, A. nomius and A. tamarii from other Aspergillus species was possible on the basis of RFLP polymorphism. Conclusions Given the abundance of Aspergillus section Flavi species A. nomius and A. flavus observed on Brazil nut, and associated risk of mycotoxin accumulation, simple identification methods for such mycotoxigenic species are of importance for Hazard Analysis Critical Control Point system implementation. The assay for the genus Aspergillus represents progress towards specific PCR identification and detection of mycotoxigenic species. PMID:24885088

  11. Industrial Accidents Triggered by Natural Hazards: an Emerging Risk Issue

    NASA Astrophysics Data System (ADS)

    Renni, Elisabetta; Krausmann, Elisabeth; Basco, Anna; Salzano, Ernesto; Cozzani, Valerio

    2010-05-01

    Natural disasters such as earthquakes, tsunamis, flooding or hurricanes have recently and dramatically hit several countries worldwide. Both direct and indirect consequences involved the population, causing on the one hand a high number of fatalities and on the other hand so relevant economical losses that the national gross product may be affected for many years. Loss of critical industrial infrastructures (electricity generation and distribution, gas pipelines, oil refineries, etc.) also occurred, causing further indirect damage to the population. In several cases, accident scenarios with large releases of hazardous materials were triggered by these natural events, causing so-called "Natech events", in which the overall damage resulted from the simultaneous consequences of the natural event and of the release of hazardous substances. Toxic releases, large fires and explosions, as well as possible long-term environmental pollution, economical losses, and overloading of emergency systems were recognised by post-event studies as the main issues of these Natech scenarios. In recent years the increasing frequency and severity of some natural hazards due to climate change has slowly increased the awareness of Natech risk as an emerging risk among the stakeholders. Indeed, the iNTeg-Risk project, co-funded by the European Commission within the 7th Framework Program specifically addresses these scenarios among new technological issues on public safety. The present study, in part carried out within the iNTeg-Risk project, was aimed at the analysis and further development of methods and tools for the assessment and mitigation of Natech accidents. Available tools and knowledge gaps in the assessment of Natech scenarios were highlighted. The analysis mainly addressed the potential impact of flood, lightning and earthquake events on industrial installations where hazardous substances are present. Preliminary screening methodologies and more detailed methods based on quantitative risk analysis were developed. Strategies based on the use of multiple information layers aiming at the identification of mitigation and early warning systems were also explored. A case-study in the Emilia-Romagna region is presented.

  12. 48 CFR 23.300 - Scope of subpart.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material Identification and Material Safety Data 23.300 Scope of subpart...

  13. 48 CFR 23.300 - Scope of subpart.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... PROGRAMS ENVIRONMENT, ENERGY AND WATER EFFICIENCY, RENEWABLE ENERGY TECHNOLOGIES, OCCUPATIONAL SAFETY, AND DRUG-FREE WORKPLACE Hazardous Material Identification and Material Safety Data 23.300 Scope of subpart...

  14. Multi-Hazard Interactions in Guatemala

    NASA Astrophysics Data System (ADS)

    Gill, Joel; Malamud, Bruce D.

    2017-04-01

    In this paper, we combine physical and social science approaches to develop a multi-scale regional framework for natural hazard interactions in Guatemala. The identification and characterisation of natural hazard interactions is an important input for comprehensive multi-hazard approaches to disaster risk reduction at a regional level. We use five transdisciplinary evidence sources to organise and populate our framework: (i) internationally-accessible literature; (ii) civil protection bulletins; (iii) field observations; (iv) stakeholder interviews (hazard and civil protection professionals); and (v) stakeholder workshop results. These five evidence sources are synthesised to determine an appropriate natural hazard classification scheme for Guatemala (6 hazard groups, 19 hazard types, and 37 hazard sub-types). For a national spatial extent (Guatemala), we construct and populate a "21×21" hazard interaction matrix, identifying 49 possible interactions between 21 hazard types. For a sub-national spatial extent (Southern Highlands, Guatemala), we construct and populate a "33×33" hazard interaction matrix, identifying 112 possible interactions between 33 hazard sub-types. Evidence sources are also used to constrain anthropogenic processes that could trigger natural hazards in Guatemala, and characterise possible networks of natural hazard interactions (cascades). The outcomes of this approach are among the most comprehensive interaction frameworks for national and sub-national spatial scales in the published literature. These can be used to support disaster risk reduction and civil protection professionals in better understanding natural hazards and potential disasters at a regional scale.

  15. Hazard Identification, Risk Assessment, and Control Measures as an Effective Tool of Occupational Health Assessment of Hazardous Process in an Iron Ore Pelletizing Industry.

    PubMed

    Rout, B K; Sikdar, B K

    2017-01-01

    With the growing numbers of iron ore pelletization industries in India, various impacts on environment and health in relation to the workplace will rise. Therefore, understanding the hazardous process is crucial in the development of effective control measures. Hazard Identification, Risk Assessment, and Control measures (HIRAC) acts as an effective tool of Occupational Health Assessment. The aim of the study was to identify all the possible hazards at different workplaces of an iron ore pelletizing industry, to conduct an occupational health risk assessment, to calculate the risk rating based on the risk matrix, and to compare the risk rating before and after the control measures. The research was a cross-sectional study done from March to December 2015 in an iron ore pelletizing industry located in Odisha, India. Data from the survey were collected by inspecting the workplace, responses of employees regarding possible hazards in their workplace, reviewing department procedure manual, work instructions, standard operating procedure, previous incident reports, material safety data sheet, first aid/injury register, and health record of employees. A total of 116 hazards were identified. Results of the paired-sample's t -test showed that mean risk rating differs before taking control measures (M = 9.13, SD = 5.99) and after taking control measures (M = 2.80, SD = 1.38) at the 0.0001 level of significance ( t = 12.6428, df = 115, N = 116, P < 0.0001, 95% CI for mean difference 5.34 to 7.32). On an average, risk reduction was about 6.33 points lower after taking control measures. The hazards having high-risk rating and above were reduced to a level considered As Low as Reasonably Practicable (ALARP) when the control measures were applied, thereby reducing the occurrence of injury or disease in the workplace.

  16. Hot wet spots of Swiss buildings - detecting clusters of flood exposure

    NASA Astrophysics Data System (ADS)

    Röthlisberger, Veronika; Zischg, Andreas; Keiler, Margreth

    2016-04-01

    Where are the hotspots of flood exposure in Switzerland? There is no single answer but rather a wide range of findings depending on the databases and methods used. In principle, the analysis of flood exposure is the overlay of two spatial datasets, one on flood hazard and one on assets, e.g. buildings. The presented study aims to test a new developed approach which is based on public available Swiss data. On the hazard side, these are two different types of flood hazard maps each representing a similar return period beyond the dimensioning of structural protection systems. When it comes to assets we use nationwide harmonized data on building, namely a complete dataset of building polygons to which we assign features as volume, residents and monetary value. For the latter we apply findings of multivariate analyses of insurance data. By overlaying building polygons with the flood hazard map we identify the exposed buildings. We analyse the resulting spatial distribution of flood exposure at different levels of scales (local to regional) using administrative units (e.g. municipalities) but also artificial grids with a corresponding size (e.g. 5 000 m). The presentation focuses on the identification of hotspots highlighting the influence of the applied data and methods, e.g. local scan statistics testing intensities within and without potential clusters or log relative exposure surfaces based on kernel intensity estimates. We find a major difference of identified hotspots between absolute values and normalized values of exposure. Whereas the hotspots of flood exposure in absolute figures mirrors the underlying distribution of buildings, the hotspots of flood exposure ratios show very different pictures. We conclude that findings on flood exposure vary depending on the data and moreover the methods used and therefore need to be communicated carefully and appropriate to different stakeholders who may use the information for decision making on flood risk management.

  17. Hazard identification and risk assessment for biologics targeting the immune system.

    PubMed

    Weir, Andrea B

    2008-01-01

    Biologic pharmaceuticals include a variety of products, such as monoclonal antibodies, fusion proteins and cytokines. Products in those classes include immunomodulatory biologics, which are intended to enhance or diminish the activity of the immune system. Immunomodulatory biologics have been approved by the U.S. FDA for a variety of indications, including cancer and inflammatory conditions. Prior to gaining approval for marketing, sponsoring companies for all types of products must demonstrate a product's safety in toxicology studies conducted in animals and show safety and efficacy in clinical trials conducted in patients. The overall goal of toxicology studies, which applies to immunomodulatory and other product types, is to identify the hazards that products pose to humans. Because biologics are generally highly selective for specific targets (receptors/epitopes), conducting toxicology studies in animal models with the target is essential. Such animals are referred to as pharmacologically relevant. Endpoints routinely included in toxicology studies, such as hematology, organ weight and histopathology, can be used to assess the effect of a product on the structure of the immune system. Additionally, specialized endpoints, such as immunophenotyping and immune function tests, can be used to define effects of immunomodulatory products on the immune system. Following hazard identification, risks posed to patients are assessed and managed. Risks can be managed through clinical trial design and risk communication, a practice that applies to immunomodulatory and other product types. Examples of risk management in clinical trial design include establishing a safe starting dose, defining the appropriate patient population and establishing appropriate patient monitoring. Risk communication starts during clinical trials and continues after product approval. A combination of hazard identification, risk assessment and risk management allows for drug development to proceed with minimum risks to patients.

  18. Microseismic Precursory Characteristics of Rock Burst Hazard in Mining Areas Near a Large Residual Coal Pillar: A Case Study from Xuzhuang Coal Mine, Xuzhou, China

    NASA Astrophysics Data System (ADS)

    Cao, An-ye; Dou, Lin-ming; Wang, Chang-bin; Yao, Xiao-xiao; Dong, Jing-yuan; Gu, Yu

    2016-11-01

    Identification of precursory characteristics is a key issue for rock burst prevention. The aim of this research is to provide a reference for assessing rock burst risk and determining potential rock burst risk areas in coal mining. In this work, the microseismic multidimensional information for the identification of rock bursts and spatial-temporal pre-warning was investigated in a specific coalface which suffered high rock burst risk in a mining area near a large residual coal pillar. Firstly, microseismicity evolution prior to a disastrous rock burst was qualitatively analysed, and the abnormal clustering of seismic sources, abnormal variations in daily total energy release, and event counts can be regarded as precursors to rock burst. Secondly, passive tomographic imaging has been used to locate high seismic activity zones and assess rock burst hazard when the coalface passes through residual pillar areas. The results show that high-velocity or velocity anomaly regions correlated well with strong seismic activities in future mining periods and that passive tomography has the potential to describe, both quantitatively and periodically, hazardous regions and assess rock burst risk. Finally, the bursting strain energy index was further used for short-term spatial-temporal pre-warning of rock bursts. The temporal sequence curve and spatial contour nephograms indicate that the status of the danger and the specific hazardous zones, and levels of rock burst risk can be quantitatively and rapidly analysed in short time and in space. The multidimensional precursory characteristic identification of rock bursts, including qualitative analysis, intermediate and short-time quantitative predictions, can guide the choice of measures implemented to control rock bursts in the field, and provides a new approach to monitor and forecast rock bursts in space and time.

  19. Identification of hazardous drinking with the Young Adult Alcohol Consequences Questionnaire: Relative operating characteristics as a function of gender.

    PubMed

    Read, Jennifer P; Haas, Amie L; Radomski, Sharon; Wickham, Robert E; Borish, Sarah E

    2016-10-01

    Heavy and problematic drinking is common on college campuses and is associated with myriad hazardous outcomes. The Young Adult Alcohol Consequences Questionnaire (YAACQ; Read et al., 2006) was developed to provide comprehensive and expedient assessment of negative consequences of young adult drinking and has been used in a number of research and clinical settings. To date, no empirically derived cutoffs for the YAACQ have been available for use in the identification of those drinkers at greatest risk. This was the objective of the present study. In a large (N = 1,311) and demographically heterogeneous multisite sample, we identified cutoff scores for the YAACQ, and the contrasted detection of hazardous drinking using these cutoffs with those recommended for the Alcohol Use Disorders Identification Test (AUDIT). We also examined whether cutoffs differed by gender. Results of receiver operating characteristic (ROC) analysis yielded cutoffs that delineate 3 levels (or zones) of hazardous drinking risk: low, moderate, and high. A cutoff of 8 differentiated those at low risk from those at moderate risk or greater, and a cutoff of 16 differentiated between moderate and high risk. These zones corresponded to other indices of risky drinking, including heavy episodic "binge" drinking, more frequent alcohol consumption, and engagement in alcohol risk behaviors. Scores differentiating low to moderate risk differed for men (8) and women (10), whereas the cutoff for high risk was the same (16) across the sexes. Findings suggest that the YAACQ can be used to reliably assess level of drinking risk among college students. Furthermore, these cut scores may be used to refer to interventions varying in intensity level, based on level of indicated alcohol risk. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  20. US Army Medical Department Journal, April - June 2007

    DTIC Science & Technology

    2007-06-01

    through early identification and occupational hazards , and food and water reduced stigma. vulnerabilities. All have various causes and effects, and all... meat barely palatable, but it was all to be had amid that remaining ones was given to food and ammunition. desolate country of want.3(pi49) The men...held in Oklahoma during the summer decades. In addition, many military missions support of 2005. uniquely hazardous industrial operations, including

  1. Hazard identification and pre-map with a simple specific tool: synthesis of application experience in handicrafts in various productive sectors.

    PubMed

    Colombini, Daniela; Occhipinti, Enrico; Peluso, Raffaele; Montomoli, Loretta

    2012-01-01

    In August 2009, an international group was founded with the task of developing a "toolkit for MSD prevention" under the IEA and in collaboration with the World Health Organization.According to the ISO standard 11228 series and the new Draft ISO TR 12259 "Application document guides for the potential user", our group developed a preliminary "mapping" methodology of occupational hazards in the craft industry, supported by software (Excel®, free download on: www.epmresearch.org).The possible users of toolkits are: members of health and safety committees; health and safety representatives; line supervisors; foremen; workers; government representatives; health workers providing basic occupational health services; occupational health and safety specialists.The proposed methodology, using specific key enters and quick assessment criteria, allows a simple ergonomics hazards identification and risk estimation to be made. It is thus possible to decide for which occupational hazards a more exhaustive risk assessment will be necessary and which occupational consultant should be involved (occupational physician, safety engineer, industrial hygienist, etc.).The methodology has been applied in different situations of small and medium craftsmanship Italian enterprises: leather goods, food, technical dental work, production of artistic ceramics and stained glass, beekeeping activities. The results are synthetically reported and discussed in this paper.

  2. Research on factors allowing a risk assessment of spore-forming pathogenic bacteria in cooked chilled foods containing vegetables: a FAIR collaborative project.

    PubMed

    Carlin, F; Girardin, H; Peck, M W; Stringer, S C; Barker, G C; Martinez, A; Fernandez, A; Fernandez, P; Waites, W M; Movahedi, S; van Leusden, F; Nauta, M; Moezelaar, R; Torre, M D; Litman, S

    2000-09-25

    Vegetables are frequent ingredients of cooked chilled foods and are frequently contaminated with spore-forming bacteria (SFB). Therefore, risk assessment studies have been carried out, including the following: hazard identification and characterisation--from an extensive literature review and expertise of the participants, B. cereus and C. botulinum were identified as the main hazards; exposure assessment--consisting of determination of the prevalence of hazardous SFB in cooked chilled foods containing vegetables and in unprocessed vegetables, and identification of SFB representative of the bacterial community in cooked chilled foods containing vegetables, determination of heat-resistance parameters and factors affecting heat resistance of SFB, determination of the growth kinetics of SFB in vegetable substrate and of the influence of controlling factors, validation of previous work in complex food systems and by challenge testing and information about process and storage conditions of cooked chilled foods containing vegetables. The paper illustrates some original results obtained in the course of the project. The results and information collected from scientific literature or from the expertise of the participants are integrated into the microbial risk assessment, using both a Bayesian belief network approach and a process risk model approach, previously applied to other foodborne hazards.

  3. Hydrothermal Liquefaction Treatment Hazard Analysis Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lowry, Peter P.; Wagner, Katie A.

    Hazard analyses were performed to evaluate the modular hydrothermal liquefaction treatment system. The hazard assessment process was performed in 2 stages. An initial assessment utilizing Hazard Identification and Preliminary Hazards Analysis (PHA) techniques identified areas with significant or unique hazards (process safety-related hazards) that fall outside of the normal operating envelope of PNNL and warranted additional analysis. The subsequent assessment was based on a qualitative What-If analysis. The analysis was augmented, as necessary, by additional quantitative analysis for scenarios involving a release of hazardous material or energy with the potential for affecting the public. The following selected hazardous scenarios receivedmore » increased attention: •Scenarios involving a release of hazardous material or energy, controls were identified in the What-If analysis table that prevent the occurrence or mitigate the effects of the release. •Scenarios with significant consequences that could impact personnel outside the immediate operations area, quantitative analyses were performed to determine the potential magnitude of the scenario. The set of “critical controls” were identified for these scenarios (see Section 4) which prevent the occurrence or mitigate the effects of the release of events with significant consequences.« less

  4. Surficial Seismology: Landslides, Glaciers, and Volcanoes in the Pacific Northwest through a Seismic Lens

    NASA Astrophysics Data System (ADS)

    Allstadt, Kate

    The following work is focused on the use of both traditional and novel seismological tools, combined with concepts from other disciplines, to investigate shallow seismic sources and hazards. The study area is the dynamic landscape of the Pacific Northwest and its wide-ranging earthquake, landslide, glacier, and volcano-related hazards. The first chapter focuses on landsliding triggered by earthquakes, with a shallow crustal earthquake in Seattle as a case study. The study demonstrates that utilizing broadband synthetic seismograms and rigorously incorporating 3D basin amplification, 1D site effects, and fault directivity, allows for a more complete assessment of regional seismically induced landslide hazard. The study shows that the hazard is severe for Seattle, and provides a framework for future probabilistic maps and near real-time hazard assessment. The second chapter focuses on landslides that generate seismic waves and how these signals can be harnessed to better understand landslide dynamics. This is demonstrated using two contrasting Pacific Northwest landslides. The 2010 Mount Meager, BC, landslide generated strong long period waves. New full waveform inversion methods reveal the time history of forces the landslide exerted on the earth that is used to quantify event dynamics. Despite having a similar volume (˜107 m3), The 2009 Nile Valley, WA, landslide did not generate observable long period motions because of its smaller accelerations, but pulses of higher frequency waves were valuable in piecing together the complex sequence of events. The final chapter details the difficulties of monitoring glacier-clad volcanoes. The focus is on small, repeating, low-frequency earthquakes at Mount Rainier that resemble volcanic earthquakes. However, based on this investigation, they are actually glacial in origin: most likely stick-slip sliding of glaciers triggered by snow loading. Identification of the source offers a view of basal glacier processes, discriminates against alarming volcanic noises, and has implications for repeating earthquakes in tectonic environments. This body of work demonstrates that by combining methods and concepts from seismology and other disciplines in new ways, we can obtain a better understanding and a fresh perspective of the physics behind the shallow seismic sources and hazards that threaten the Pacific Northwest.

  5. Assessing community vulnerabilities to natural hazards on the Island of Hawaii

    NASA Astrophysics Data System (ADS)

    Nishioka, Chris; Delparte, Donna

    2010-05-01

    The island of Hawaii is susceptible to numerous natural hazards such as tsunamis, flooding, lava flow, earthquakes, hurricanes, landslides, wildfires and storm surge. The impact of a natural disaster on the island's communities has the potential to endanger peoples' lives and threaten critical infrastructure, homes, businesses and economic drivers such as tourism. A Geographic Information System (GIS) has the ability to assess community vulnerabilities by examining the spatial relationships between hazard zones, socioeconomic infrastructure and demographic data. By drawing together existing datasets, GIS was used to examine a number of community vulnerabilities. Key areas of interest were government services, utilities, property assets, industry and transportation. GIS was also used to investigate population dynamics in hazard zones. Identification of community vulnerabilities from GIS analysis can support mitigation measures and assist planning and response measures to natural hazards.

  6. Label-free pharmacological profiling based on dynamic mass redistribution for characterization and authentication of hazardous natural products.

    PubMed

    Song, Hui-Peng; Wang, Hong; Zhao, Xiaoai; He, Ling; Zhong, Huailing; Wu, Si-Qi; Li, Ping; Yang, Hua

    2017-07-05

    Natural products are becoming increasingly popular in multiple fields involving medicines, foods and beverages. However, due to the frequent occurrence of poisoning incidents, their toxicity and safety have caused a serious concern. Here we report a method of biosensor-based two-phase pharmacological profiling (BTPP) for discovery, monitor and control of receptor-targeted natural products. BTPP uses a resonant waveguide grating biosensor for label-free and non-invasive detection of intracellular dynamic mass redistribution (DMR), a phenomenon caused by protein relocalization after receptors receiving stimulation from toxicants. The method can not only facilitate the identification of hazardous materials but also quantify their bioactivity by EC 50 . As a proof of concept, the method was successfully applied to recognize Daturae Flos (DF), an herb that can antagonize muscarinic acetylcholine M 2 receptor and further cause poisoning, from other easily confused species. BTPP combined with high performance liquid chromatography revealed that scopolamine and hyoscyamine in DF were the key marker compounds. Moreover, the method accurately picked out 2 M 2 receptor antagonists from 25 natural compounds, displaying its potential in high-throughput screening. This study provides a systematic illustration about the establishment, applicability and advantages of BTPP, which contributes to the safety assessment of natural products in related fields. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Automated identification of potential snow avalanche release areas based on digital elevation models

    NASA Astrophysics Data System (ADS)

    Bühler, Y.; Kumar, S.; Veitinger, J.; Christen, M.; Stoffel, A.; Snehmani

    2013-05-01

    The identification of snow avalanche release areas is a very difficult task. The release mechanism of snow avalanches depends on many different terrain, meteorological, snowpack and triggering parameters and their interactions, which are very difficult to assess. In many alpine regions such as the Indian Himalaya, nearly no information on avalanche release areas exists mainly due to the very rough and poorly accessible terrain, the vast size of the region and the lack of avalanche records. However avalanche release information is urgently required for numerical simulation of avalanche events to plan mitigation measures, for hazard mapping and to secure important roads. The Rohtang tunnel access road near Manali, Himachal Pradesh, India, is such an example. By far the most reliable way to identify avalanche release areas is using historic avalanche records and field investigations accomplished by avalanche experts in the formation zones. But both methods are not feasible for this area due to the rough terrain, its vast extent and lack of time. Therefore, we develop an operational, easy-to-use automated potential release area (PRA) detection tool in Python/ArcGIS which uses high spatial resolution digital elevation models (DEMs) and forest cover information derived from airborne remote sensing instruments as input. Such instruments can acquire spatially continuous data even over inaccessible terrain and cover large areas. We validate our tool using a database of historic avalanches acquired over 56 yr in the neighborhood of Davos, Switzerland, and apply this method for the avalanche tracks along the Rohtang tunnel access road. This tool, used by avalanche experts, delivers valuable input to identify focus areas for more-detailed investigations on avalanche release areas in remote regions such as the Indian Himalaya and is a precondition for large-scale avalanche hazard mapping.

  8. Automatic extraction of blocks from 3D point clouds of fractured rock

    NASA Astrophysics Data System (ADS)

    Chen, Na; Kemeny, John; Jiang, Qinghui; Pan, Zhiwen

    2017-12-01

    This paper presents a new method for extracting blocks and calculating block size automatically from rock surface 3D point clouds. Block size is an important rock mass characteristic and forms the basis for several rock mass classification schemes. The proposed method consists of four steps: 1) the automatic extraction of discontinuities using an improved Ransac Shape Detection method, 2) the calculation of discontinuity intersections based on plane geometry, 3) the extraction of block candidates based on three discontinuities intersecting one another to form corners, and 4) the identification of "true" blocks using an improved Floodfill algorithm. The calculated block sizes were compared with manual measurements in two case studies, one with fabricated cardboard blocks and the other from an actual rock mass outcrop. The results demonstrate that the proposed method is accurate and overcomes the inaccuracies, safety hazards, and biases of traditional techniques.

  9. 48 CFR 970.2303 - Hazardous materials identification and material safety.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Environment, Energy and Water Efficiency, Renewable Energy Technologies, Occupational Safety and Drug-Free Work Place 970...

  10. 48 CFR 970.2303 - Hazardous materials identification and material safety.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Environment, Energy and Water Efficiency, Renewable Energy Technologies, Occupational Safety and Drug-Free Work Place 970...

  11. 48 CFR 970.2303 - Hazardous materials identification and material safety.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Environment, Energy and Water Efficiency, Renewable Energy Technologies, Occupational Safety and Drug-Free Work Place 970...

  12. 48 CFR 970.2303 - Hazardous materials identification and material safety.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Environment, Energy and Water Efficiency, Renewable Energy Technologies, Occupational Safety and Drug-Free Work Place 970...

  13. 40 CFR 63.2182 - What records must I keep?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Standards for Hazardous Air Pollutants: Manufacturing of Nutritional Yeast Notification, Reports, and...) Fermentation stage for which you are using the fermenter. (3) Unique CEMS equipment identification number. ...

  14. 48 CFR 970.2303 - Hazardous materials identification and material safety.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... OF ENERGY AGENCY SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Environment, Energy and Water Efficiency, Renewable Energy Technologies, Occupational Safety and Drug-Free Work Place 970...

  15. Hazard recognition in mining: A psychological perspective. Information circular/1995

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Perdue, C.W.; Kowalski, K.M.; Barrett, E.A.

    1995-07-01

    This U.S. Bureau of Mines report considers, from a psychological perspective, the perceptual process by which miners recognize and respond to mining hazards. It proposes that if the hazard recognition skills of miners can be improved, mining accidents may be reduced to a significant degree. Prior studies of hazard perception in mining are considered, as are relevant studies from investigations of military target identification, pilot and gunnery officer training, transportation safety, automobile operator behavior, as well as research into sensory functioning and visual information processing. A general model of hazard perception is introduced, and selected concepts from the psychology ofmore » perception that are applicable to the detection of mining hazards are reviewed. Hazard recognition is discussed as a function of the perceptual cues available to the miner as well as the cognitive resources and strategies employed by the miner. The development of expertise in resonding to hazards is related to individual differences in the experience, aptitude, and personality of the worker. Potential applications to miner safety and training are presented.« less

  16. Earth based approaches to enhancing the health and safety of space operations

    NASA Technical Reports Server (NTRS)

    Koller, A. M., Jr.

    1985-01-01

    This paper provides an overview of the current state of our earth based knowledge of space safety hazards; identification of several key areas of concern for space operations; and proposed approaches to providing technology enhancement and information needed to improve the health and safety to those conducting space operations. Included are a review of the identified hazards for space oeprations by hazard classification; a summarization of the information currently available on space experiences and an assessment of potential hazards for long duration spaceflight; a discussion of potential failure modes and their significance for Space Station work: and an assessment of current work which indicates additional research and experimentation which can only be accomplished in actual space missions.

  17. UV-Enhanced IR Raman System for Identifying Biohazards

    NASA Technical Reports Server (NTRS)

    Stirbl, Robert; Moynihan, Philip; Lane, Arthur

    2003-01-01

    An instrumentation system that would include an ultraviolet (UV) laser or light-emitting diode, an infrared (IR) laser, and the equivalent of an IR Raman spectrometer has been proposed to enable noncontact identification of hazardous biological agents and chemicals. In prior research, IR Raman scattering had shown promise as a means of such identification, except that the Raman-scattered light was often found to be too weak to be detected or to enable unambiguous identification in practical applications. The proposed system would utilize UV illumination as part of a two-level optical-pumping scheme to intensify the Raman signal sufficiently to enable positive identification.

  18. Reprint of "CON4EI: Bovine Corneal Opacity and Permeability (BCOP) test for hazard identification and labelling of eye irritating chemicals".

    PubMed

    Verstraelen, Sandra; Maglennon, Gareth; Hollanders, Karen; Boonen, Francis; Adriaens, Els; Alépée, Nathalie; Drzewiecka, Agnieszka; Gruszka, Katarzyna; Kandarova, Helena; Willoughby, Jamin A; Guest, Robert; Schofield, Jane; Van Rompay, An R

    2018-06-01

    Assessment of ocular irritation potential is an international regulatory requirement in the safety evaluation of industrial and consumer products. None in vitro ocular irritation assays are capable of fully categorizing chemicals as stand-alone. Therefore, the CEFIC-LRI-AIMT6-VITO CON4EI consortium assessed the reliability of eight in vitro test methods and computational models as well as established a tiered-testing strategy. One of the selected assays was Bovine Corneal Opacity and Permeability (BCOP). In this project, the same corneas were used for measurement of opacity using the OP-KIT, the Laser Light-Based Opacitometer (LLBO) and for histopathological analysis. The results show that the accuracy of the BCOP OP-KIT in identifying Cat 1 chemicals was 73.8% while the accuracy was 86.3% for No Cat chemicals. BCOP OP-KIT false negative results were often related to an in vivo classification driven by conjunctival effects only. For the BCOP LLBO, the accuracy in identifying Cat 1 chemicals was 74.4% versus 88.8% for No Cat chemicals. The BCOP LLBO seems very promising for the identification of No Cat liquids but less so for the identification of solids. Histopathology as an additional endpoint to the BCOP test method does not reduce the false negative rate substantially for in vivo Cat 1 chemicals. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. CON4EI: Bovine Corneal Opacity and Permeability (BCOP) test for hazard identification and labelling of eye irritating chemicals.

    PubMed

    Verstraelen, Sandra; Maglennon, Gareth; Hollanders, Karen; Boonen, Francis; Adriaens, Els; Alépée, Nathalie; Drzewiecka, Agnieszka; Gruszka, Katarzyna; Kandarova, Helena; Willoughby, Jamin A; Guest, Robert; Schofield, Jane; Van Rompay, An R

    2017-10-01

    Assessment of ocular irritation potential is an international regulatory requirement in the safety evaluation of industrial and consumer products. None in vitro ocular irritation assays are capable of fully categorizing chemicals as stand-alone. Therefore, the CEFIC-LRI-AIMT6-VITO CON4EI consortium assessed the reliability of eight in vitro test methods and computational models as well as established a tiered-testing strategy. One of the selected assays was Bovine Corneal Opacity and Permeability (BCOP). In this project, the same corneas were used for measurement of opacity using the OP-KIT, the Laser Light-Based Opacitometer (LLBO) and for histopathological analysis. The results show that the accuracy of the BCOP OP-KIT in identifying Cat 1 chemicals was 73.8% while the accuracy was 86.3% for No Cat chemicals. BCOP OP-KIT false negative results were often related to an in vivo classification driven by conjunctival effects only. For the BCOP LLBO, the accuracy in identifying Cat 1 chemicals was 74.4% versus 88.8% for No Cat chemicals. The BCOP LLBO seems very promising for the identification of No Cat liquids but less so for the identification of solids. Histopathology as an additional endpoint to the BCOP test method does not reduce the false negative rate substantially for in vivo Cat 1 chemicals. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Tidal triggering of earthquakes suggests poroelastic behavior on the San Andreas Fault

    DOE PAGES

    Delorey, Andrew A.; van der Elst, Nicholas J.; Johnson, Paul Allan

    2016-12-28

    Tidal triggering of earthquakes is hypothesized to provide quantitative information regarding the fault's stress state, poroelastic properties, and may be significant for our understanding of seismic hazard. To date, studies of regional or global earthquake catalogs have had only modest successes in identifying tidal triggering. We posit that the smallest events that may provide additional evidence of triggering go unidentified and thus we developed a technique to improve the identification of very small magnitude events. We identify events applying a method known as inter-station seismic coherence where we prioritize detection and discrimination over characterization. Here we show tidal triggering ofmore » earthquakes on the San Andreas Fault. We find the complex interaction of semi-diurnal and fortnightly tidal periods exposes both stress threshold and critical state behavior. Lastly, our findings reveal earthquake nucleation processes and pore pressure conditions – properties of faults that are difficult to measure, yet extremely important for characterizing earthquake physics and seismic hazards.« less

  1. Analysis of Operational Hazards and Safety Requirements for Traffic Aware Strategic Aircrew Requests (TASAR)

    NASA Technical Reports Server (NTRS)

    Koczo, Stefan, Jr.

    2013-01-01

    Safety analyses of the Traffic Aware Strategic Aircrew Requests (TASAR) Electronic Flight Bag (EFB) application are provided to establish its Failure Effects Classification which affects certification and operational approval requirements. TASAR was developed by NASA Langley Research Center to offer flight path improvement opportunities to the pilot during flight for operational benefits (e.g., reduced fuel, flight time). TASAR, using own-ship and network-enabled information concerning the flight and its environment, including weather and Air Traffic Control (ATC) system constraints, provides recommended improvements to the flight trajectory that the pilot can choose to request via Change Requests to ATC for revised clearance. This study reviews the Change Request process of requesting updates to the current clearance, examines the intended function of TASAR, and utilizes two safety assessment methods to establish the Failure Effects Classification of TASAR. Considerable attention has been given in this report to the identification of operational hazards potentially associated with TASAR.

  2. Tidal triggering of earthquakes suggests poroelastic behavior on the San Andreas Fault

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Delorey, Andrew A.; van der Elst, Nicholas J.; Johnson, Paul Allan

    Tidal triggering of earthquakes is hypothesized to provide quantitative information regarding the fault's stress state, poroelastic properties, and may be significant for our understanding of seismic hazard. To date, studies of regional or global earthquake catalogs have had only modest successes in identifying tidal triggering. We posit that the smallest events that may provide additional evidence of triggering go unidentified and thus we developed a technique to improve the identification of very small magnitude events. We identify events applying a method known as inter-station seismic coherence where we prioritize detection and discrimination over characterization. Here we show tidal triggering ofmore » earthquakes on the San Andreas Fault. We find the complex interaction of semi-diurnal and fortnightly tidal periods exposes both stress threshold and critical state behavior. Lastly, our findings reveal earthquake nucleation processes and pore pressure conditions – properties of faults that are difficult to measure, yet extremely important for characterizing earthquake physics and seismic hazards.« less

  3. Tidal triggering of earthquakes suggests poroelastic behavior on the San Andreas Fault

    USGS Publications Warehouse

    Delorey, Andrew; Van Der Elst, Nicholas; Johnson, Paul

    2017-01-01

    Tidal triggering of earthquakes is hypothesized to provide quantitative information regarding the fault's stress state, poroelastic properties, and may be significant for our understanding of seismic hazard. To date, studies of regional or global earthquake catalogs have had only modest successes in identifying tidal triggering. We posit that the smallest events that may provide additional evidence of triggering go unidentified and thus we developed a technique to improve the identification of very small magnitude events. We identify events applying a method known as inter-station seismic coherence where we prioritize detection and discrimination over characterization. Here we show tidal triggering of earthquakes on the San Andreas Fault. We find the complex interaction of semi-diurnal and fortnightly tidal periods exposes both stress threshold and critical state behavior. Our findings reveal earthquake nucleation processes and pore pressure conditions – properties of faults that are difficult to measure, yet extremely important for characterizing earthquake physics and seismic hazards.

  4. Elimination of bioweapons agents from forensic samples during extraction of human DNA.

    PubMed

    Timbers, Jason; Wilkinson, Della; Hause, Christine C; Smith, Myron L; Zaidi, Mohsin A; Laframboise, Denis; Wright, Kathryn E

    2014-11-01

    Collection of DNA for genetic profiling is a powerful means for the identification of individuals responsible for crimes and terrorist acts. Biologic hazards, such as bacteria, endospores, toxins, and viruses, could contaminate sites of terrorist activities and thus could be present in samples collected for profiling. The fate of these hazards during DNA isolation has not been thoroughly examined. Our goals were to determine whether the DNA extraction process used by the Royal Canadian Mounted Police eliminates or neutralizes these agents and if not, to establish methods that render samples safe without compromising the human DNA. Our results show that bacteria, viruses, and toxins were reduced to undetectable levels during DNA extraction, but endospores remained viable. Filtration of samples after DNA isolation eliminated viable spores from the samples but left DNA intact. We also demonstrated that contamination of samples with some bacteria, endospores, and toxins for longer than 1 h compromised the ability to complete genetic profiling. © 2014 American Academy of Forensic Sciences.

  5. Ethical and scientific issues of nanotechnology in the workplace.

    PubMed

    Schulte, Paul A; Salamanca-Buentello, Fabio

    2007-01-01

    In the absence of scientific clarity about the potential health effects of occupational exposure to nanoparticles, a need exists for guidance in decision making about hazards, risks, and controls. An identification of the ethical issues involved may be useful to decision makers, particularly employers, workers, investors, and health authorities. Because the goal of occupational safety and health is the prevention of disease in workers, the situations that have ethical implications that most affect workers have been identified. These situations include the a) identification and communication of hazards and risks by scientists, authorities, and employers; b) workers' acceptance of risk; c) selection and implementation of controls; d) establishment of medical screening programs; and e) investment in toxicologic and control research. The ethical issues involve the unbiased determination of hazards and risks, nonmaleficence (doing no harm), autonomy, justice, privacy, and promoting respect for persons. As the ethical issues are identified and explored, options for decision makers can be developed. Additionally, societal deliberations about workplace risks of nanotechnologies may be enhanced by special emphasis on small businesses and adoption of a global perspective.

  6. Ethical and scientific issues of nanotechnology in the workplace.

    PubMed

    Schulte, Paul A; Salamanca-Buentello, Fabio

    2007-01-01

    In the absence of scientific clarity about the potential health effects of occupational exposure to nanoparticles, a need exists for guidance in decisionmaking about hazards, risks, and controls. An identification of the ethical issues involved may be useful to decision makers, particularly employers, workers, investors, and health authorities. Because the goal of occupational safety and health is the prevention of disease in workers, the situations that have ethical implications that most affect workers have been identified. These situations include the a) identification and communication of hazards and risks by scientists, authorities, and employers; b) workers' acceptance of risk; c) selection and implementation of controls; d) establishment of medical screening programs; and e) investment in toxicologic and control research. The ethical issues involve the unbiased determination of hazards and risks, nonmaleficence (doing no harm), autonomy, justice, privacy, and promoting respect for persons. As the ethical issues are identified and explored, options for decision makers can be developed. Additionally, societal deliberations about workplace risks of nanotechnologies may be enhanced by special emphasis on small businesses and adoption of a global perspective.

  7. Ethical and Scientific Issues of Nanotechnology in the Workplace

    PubMed Central

    Schulte, Paul A.; Salamanca-Buentello, Fabio

    2007-01-01

    In the absence of scientific clarity about the potential health effects of occupational exposure to nanoparticles, a need exists for guidance in decisionmaking about hazards, risks, and controls. An identification of the ethical issues involved may be useful to decision makers, particularly employers, workers, investors, and health authorities. Because the goal of occupational safety and health is the prevention of disease in workers, the situations that have ethical implications that most affect workers have been identified. These situations include the a) identification and communication of hazards and risks by scientists, authorities, and employers; b) workers’ acceptance of risk; c) selection and implementation of controls; d) establishment of medical screening programs; and e) investment in toxicologic and control research. The ethical issues involve the unbiased determination of hazards and risks, nonmaleficence (doing no harm), autonomy, justice, privacy, and promoting respect for persons. As the ethical issues are identified and explored, options for decision makers can be developed. Additionally, societal deliberations about workplace risks of nanotechnologies may be enhanced by special emphasis on small businesses and adoption of a global perspective. PMID:17366812

  8. Identification of the traditional methods of newborn mothers regarding jaundice in Turkey.

    PubMed

    Aydin, Diler; Karaca Ciftci, Esra; Karatas, Hulya

    2014-02-01

    To detect traditional methods applied for the treatment of newborn jaundice by mothers in Turkey. Traditional methods are generally used in our society. Instead of using medical services, people often use already-known traditional methods to treat the disease. In such cases, the prognosis of the disease generally becomes worse, the treatment period longer and healthcare costs higher, and more medicine is used. A cross-sectional descriptive study. The participants of this study were 229 mothers with newborn babies aged 0-28 days in one university hospital and one public children's hospital in Sanliurfa. The study was conducted between March and May 2012. In this research, the Beliefs and Traditional Methods of Mothers for Jaundice Questionnaire, which was formed by searching the relevant literature, is used as a data collection tool. The data are evaluated by percentage distributions. Mothers apply conventional practices in cases of health problems such as jaundice, and application of these methods is important to mothers. Moreover, mothers reported applying hazardous conventional methods in cases of neonatal jaundice, such as cutting the area between the baby's eyebrows with a blade, cutting the back of the ear and the body and burning the body, which are not applied in different cultures. Education regarding the effects of conventional methods being applied in families should be provided, and the results of this study should serve to guide further studies in assessing the effects of such education. This approach can support beneficial practices involving individual care and prevent the negative health effects of hazardous practices. © 2013 John Wiley & Sons Ltd.

  9. The alcohol use disorders identification test (AUDIT): validation of a Nepali version for the detection of alcohol use disorders and hazardous drinking in medical settings

    PubMed Central

    2012-01-01

    Background Alcohol problems are a major health issue in Nepal and remain under diagnosed. Increase in consumption are due to many factors, including advertising, pricing and availability, but accurate information is lacking on the prevalence of current alcohol use disorders. The AUDIT (Alcohol Use Disorder Identification Test) questionnaire developed by WHO identifies individuals along the full spectrum of alcohol misuse and hence provides an opportunity for early intervention in non-specialty settings. This study aims to validate a Nepali version of AUDIT among patients attending a university hospital and assess the prevalence of alcohol use disorders along the full spectrum of alcohol misuse. Methods This cross-sectional study was conducted in patients attending the medicine out-patient department of a university hospital. DSM-IV diagnostic categories (alcohol abuse and alcohol dependence) were used as the gold standard to calculate the diagnostic parameters of the AUDIT. Hazardous drinking was defined as self reported consumption of ≥21 standard drink units per week for males and ≥14 standard drink units per week for females. Results A total of 1068 individuals successfully completed the study. According to DSM-IV, drinkers were classified as follows: No alcohol problem (n=562; 59.5%), alcohol abusers (n= 78; 8.3%) and alcohol dependent (n=304; 32.2%). The prevalence of hazardous drinker was 67.1%. The Nepali version of AUDIT is a reliable and valid screening tool to identify individuals with alcohol use disorders in the Nepalese population. AUDIT showed a good capacity to discriminate dependent patients (with AUDIT ≥11 for both the gender) and hazardous drinkers (with AUDIT ≥5 for males and ≥4 for females). For alcohol dependence/abuse the cut off values was ≥9 for both males and females. Conclusion The AUDIT questionnaire is a good screening instrument for detecting alcohol use disorders in patients attending a university hospital. This study also reveals a very high prevalence of alcohol use disorders in Nepal. PMID:23039711

  10. The Alcohol Use Disorders Identification Test for Consumption (AUDIT-C) is more useful than pre-existing laboratory tests for predicting hazardous drinking: a cross-sectional study.

    PubMed

    Fujii, Hideki; Nishimoto, Naoki; Yamaguchi, Seiko; Kurai, Osamu; Miyano, Masato; Ueda, Wataru; Oba, Hiroko; Aoki, Tetsuya; Kawada, Norifumi; Okawa, Kiyotaka

    2016-05-10

    It is important to screen for alcohol consumption and drinking customs in a standardized manner. The aim of this study was 1) to investigate whether the AUDIT score is useful for predicting hazardous drinking using optimal cutoff scores and 2) to use multivariate analysis to evaluate whether the AUDIT score was more useful than pre-existing laboratory tests for predicting hazardous drinking. A cross-sectional study using the Alcohol Use Disorders Identification Test (AUDIT) was conducted in 334 outpatients who consulted our internal medicine department. The patients completed self-reported questionnaires and underwent a diagnostic interview, physical examination, and laboratory testing. Forty (23 %) male patients reported daily alcohol consumption ≥ 40 g, and 16 (10 %) female patients reported consumption ≥ 20 g. The optimal cutoff values of hazardous drinking were calculated using a 10-fold cross validation, resulting in an optimal AUDIT score cutoff of 8.2, with a sensitivity of 95.5 %, specificity of 87.0 %, false positive rate of 13.0 %, false negative rate of 4.5 %, and area under the receiver operating characteristic curve of 0.97. Multivariate analysis revealed that the most popular short version of the AUDIT consisting solely of its three consumption items (AUDIT-C) and patient sex were significantly associated with hazardous drinking. The aspartate transaminase (AST)/alanine transaminase (ALT) ratio and mean corpuscular volume (MCV) were weakly significant. This study showed that the AUDIT score and particularly the AUDIT-C score were more useful than the AST/ALT ratio and MCV for predicting hazardous drinking.

  11. Climate Change Indicator for Hazard Identification of Indian North West Coast Marine Environment Using Synthetic Aperture Radar (sar)

    NASA Astrophysics Data System (ADS)

    Gambheer, Phani Raj

    2012-07-01

    Stormwater runoff, Petroleum Hydrocarbon plumes are found abundantly near coastal cities, coastal population settlements especially in developing nations as more than half the world's human population. Ever increasing coastal populations and development in coastal areas have led to increased loading of toxic substances, nutrients and pathogens. These hazards cause deleterious effects on the population in many ways directly or indirectly which lead to algal blooms, hypoxia, beach closures, and damage to coastal fisheries. Hence these pollution hazards are important and the coastal administrations and people need to be aware of such a danger lurking very close to them. These hazards due to their small size, dynamic and episodic in nature are difficult to be visualized or to sample using in-situ traditional scientific methods. Natural obstructions like cloud cover and complex coastal circulations can hinder to detect and monitor such occurrences in the selected areas chosen for observations. This study takes recourse to Synthetic Aperture Radar (SAR) imagery because the pollution hazards are easily detectable as surfactants are deposited on the sea surface, along with nutrients and pathogens, smoothing capillary and small gravity waves to produce areas of reduced backscatter compared with surrounding ocean. These black spots can be termed as `Ecologic Indicator' and formed probably due to stronger thermal stratification, a deepening event of thermocline. SAR imagery that delivers useful data better than others regardless of darkness or cloud cover, should be made as an important observational tool for assessment and monitoring marine pollution hazards in the areas close to coastal regions. Till now the effects of climate change, sea level rise and global warming seems to have not affected the coastal populace of India in intrusions of sea water but it takes significance to the human health as the tides dominate these latitudes with bringing these polluted waters. KEY WORDS Coastal, ecologic, estuarine, hazard, indicator, marine, pollution, stressor, tides

  12. WE-G-BRA-06: Application of Systems and Control Theory-Based Hazard Analysis to Radiotherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pawlicki, T; Samost, A; Leveson, N

    Purpose: The process of delivering radiation occurs in a complex socio-technical system heavily reliant on human operators. Furthermore, both humans and software are notoriously challenging to account for in traditional hazard analysis models. High reliability industries such as aviation have approached this problem through using hazard analysis techniques grounded in systems and control theory. The purpose of this work is to apply the Systems Theoretic Accident Model Processes (STAMP) hazard model to radiotherapy. In particular, the System-Theoretic Process Analysis (STPA) approach is used to perform a hazard analysis of a proposed on-line adaptive cranial radiosurgery procedure that omits the CTmore » Simulation step and uses only CBCT for planning, localization, and treatment. Methods: The STPA procedure first requires the definition of high-level accidents and hazards leading to those accidents. From there, hierarchical control structures were created followed by the identification and description of control actions for each control structure. Utilizing these control structures, unsafe states of each control action were created. Scenarios contributing to unsafe control action states were then identified and translated into system requirements to constrain process behavior within safe boundaries. Results: Ten control structures were created for this new CBCT-only process which covered the areas of hospital and department management, treatment design and delivery, and vendor service. Twenty three control actions were identified that contributed to over 80 unsafe states of those control actions resulting in over 220 failure scenarios. Conclusion: The interaction of people, hardware, and software are highlighted through the STPA approach. STPA provides a hierarchical model for understanding the role of management decisions in impacting system safety so that a process design requirement can be traced back to the hazard and accident that it is intended to mitigate. Varian Medical Systems, Inc.« less

  13. Airborne EM survey in volcanoes : Application to a volcanic hazards assessment

    NASA Astrophysics Data System (ADS)

    Mogi, T.

    2010-12-01

    Airborne electromagnetics (AEM) is a useful tool for investigating subsurface structures of volcanoes because it can survey large areas involving inaccessible areas. Disadvantages include lower accuracy and limited depth of investigation. AEM has been widely used in mineral exploration in frontier areas, and have been applying to engineering and environmental fields, particularly in studies involving active volcanoes. AEM systems typically comprise a transmitter and a receiver on an aircraft or in a towed bird, and although effective for surveying large areas, their penetration depth is limited because the distance between the transmitter and receiver is small and higher-frequency signals are used. To explore deeper structures using AEM, a semi-airborne system called GRounded Electrical source Airborne Transient ElectroMagnetics (GREATEM) has been developed. The system uses a grounded-electrical-dipole as the transmitter and generates horizontal electric fields. The GREATEM technology, first proposed by Mogi et al. (1998), has recently been improved and used in practical surveys (Mogi et al., 2009). The GREATEM survey system was developed to increase the depth of investigation possible using AEM. The method was tested in some volcanoes at 2004-2005. Here I will talk about some results of typical AEM surveys and GREATEM surveys in some volcanoes in Japan to mitigate hazards associated with volcano eruption. Geologic hazards caused by volcanic eruptions can be mitigated by a combination of prediction, preparedness and land-use control. Risk management depends on the identification of hazard zones and forecasting of eruptions. Hazard zoning involves the mapping of deposits which have formed during particular phases of volcanic activity and their extrapolation to identify the area which would be likely to suffer a similar hazard at some future time. The mapping is usually performed by surface geological surveys of volcanic deposits. Resistivity mapping by AEM is useful tool to identify each volcanic deposit on the surface and at shallower depth as well. This suggests that more efficient hazard map involving subsurface information can be supplied by AEM resistivity mapping.

  14. Alcohol misuse, risky sexual behaviors, and HIV or syphilis infections among Chinese men who have sex with men

    PubMed Central

    Liu, Yu; Ruan, Yuhua; Strauss, Shiela M.; Yin, Lu; Liu, Hongjie; Amico, K. Rivet; Zhang, Chen; Shao, Yiming; Qian, Han-Zhu; Vermund, Sten H.

    2017-01-01

    Background Few studies have employed standardized alcohol misuse measures to assess relationships with sexual risk and HIV/syphilis infections among Chinese men who have sex with men (MSM). Methods We conducted a cross-sectional study among MSM in Beijing during 2013–2014. An interviewer-administered survey was conducted to collect data on sociodemographics, high-risk behaviors, and alcohol use/misuse patterns (hazardous/binge drinking and risk of alcohol dependence) in the past 3 months using Alcohol Use Disorder Identification Test-Consumption (AUDIT-C). We defined AUDIT-C score ≥4 as recent hazardous drinkers, and drinking ≥6 standard drinks on one occasion as recent binge drinkers. Results Of 3,588 participants, 14.4% reported hazardous drinking, 16.8% reported binge drinking. Hazardous and binge drinking are both associated with these factors (p<0.05): older age, being migrants, living longer in Beijing, township/village origin, being employed, higher income, self-perceived low/no HIV risk, and sex-finding via non-Internet venues. Hazardous (vs non-hazardous) or binge (vs. non-binge) drinkers were more likely to use illicit drugs, use alcohol before sex, have multiple partnerships, pay for sex, and have condomless insertive anal intercourse. MSM who reported binge (AOR, 1.34, 95% CI, 1.02–1.77) or hazardous (AOR, 1.36, 95% CI, 1.02–1.82) drinking were more likely to be HIV-infected. MSM at high risk of current alcohol dependence (AUDIT-C ≥8) were more likely to be HIV- (AOR, 2.37, 95% CI, 1.39–4.04) or syphilis-infected (AOR, 1.96, 95% CI, 1.01–3.86). Conclusions Recent alcohol misuse was associated with increased sexual and HIV/syphilis risks among Chinese MSM, emphasizing the needs of implementing alcohol risk reduction programs in this population. PMID:27723554

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fenner-Crisp, P.

    The application of information available for risk assessment from the federal perspective is described. Different federal agencies conduct varying degrees of hazard evaluation, and some also generate empirical data. The role of the Agency for Toxic Substances and Disease Registry in hazard assessments of potential public health impacts of Superfund sites includes identification of the 275 most significant substances. ATSDR is responsible for preparing toxicological profiles. ATSDR also identifies data gaps and needs critical to adequately assessing human health impacts.

  16. Plenary: Progress in Regional Landslide Hazard Assessment—Examples from the USA

    USGS Publications Warehouse

    Baum, Rex L.; Schulz, William; Brien, Dianne L.; Burns, William J.; Reid, Mark E.; Godt, Jonathan W.

    2014-01-01

    Landslide hazard assessment at local and regional scales contributes to mitigation of landslides in developing and densely populated areas by providing information for (1) land development and redevelopment plans and regulations, (2) emergency preparedness plans, and (3) economic analysis to (a) set priorities for engineered mitigation projects and (b) define areas of similar levels of hazard for insurance purposes. US Geological Survey (USGS) research on landslide hazard assessment has explored a range of methods that can be used to estimate temporal and spatial landslide potential and probability for various scales and purposes. Cases taken primarily from our work in the U.S. Pacific Northwest illustrate and compare a sampling of methods, approaches, and progress. For example, landform mapping using high-resolution topographic data resulted in identification of about four times more landslides in Seattle, Washington, than previous efforts using aerial photography. Susceptibility classes based on the landforms captured 93 % of all historical landslides (all types) throughout the city. A deterministic model for rainfall infiltration and shallow landslide initiation, TRIGRS, was able to identify locations of 92 % of historical shallow landslides in southwest Seattle. The potentially unstable areas identified by TRIGRS occupied only 26 % of the slope areas steeper than 20°. Addition of an unsaturated infiltration model to TRIGRS expands the applicability of the model to areas of highly permeable soils. Replacement of the single cell, 1D factor of safety with a simple 3D method of columns improves accuracy of factor of safety predictions for both saturated and unsaturated infiltration models. A 3D deterministic model for large, deep landslides, SCOOPS, combined with a three-dimensional model for groundwater flow, successfully predicted instability in steep areas of permeable outwash sand and topographic reentrants. These locations are consistent with locations of large, deep, historically active landslides. For an area in Seattle, a composite of the three maps illustrates how maps produced by different approaches might be combined to assess overall landslide potential. Examples from Oregon, USA, illustrate how landform mapping and deterministic analysis for shallow landslide potential have been adapted into standardized methods for efficiently producing detailed landslide inventory and shallow landslide susceptibility maps that have consistent content and format statewide.

  17. 40 CFR 272.2201 - Texas State-Administered program: Final authorization.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) (Checklist 187) 64 FR 36365 June 8, 2000. Zinc Fertilizers Made from Recycled Hazardous Secondary Materials... 16, 2001. Inorganic Chemical Manufacturing Waste Identification and Listing (HSWA/Non-HSWA...

  18. Risk assessment in infrastructure in educational institution: A study in Malaysia

    NASA Astrophysics Data System (ADS)

    Rasdan Ismail, Ahmad; Adilah Hamzah, Noor; Kamilah Makhtar, Nor; Azhar Mat Daud, Khairul; Zulkarnaen Khidzir, Nik; Husna Che Hassan, Nurul; Arifpin Mansor, Muhamad

    2017-10-01

    This particular study was conducted to assess the hazard exposure in education institution and to highlight the possible risk level available. The assessment utilised is Hazard Identification, Risk Assessment and Risk Control (HIRARC). There was a 2008’s form in order to determine the risk level of the hazard. There were over 111 of education institutions were selected around Malaysia to perform this assessment. Area chosen for each institution was office, playing field, canteen, classroom, toilet and drainage. By referring HIRARC Guideline 2008, the determination of risk rank is measure based on the formula likelihood multiply severity and the rank need to refer from risk matrix standard. There are several hazard have be found and shows the high, medium and low of risk level. The higher level of risk was discussed in the study which is hazard found in playing field and hazard in office. There several hazard that need to be control by education management to avoid increase of case accident in Education Sector, Malaysia. As conclusion, the exposure hazard among the staff and educators is high and further action and control are needed. Further study need to explore the best recommendation for control measure of the hazard exposed by education institution.

  19. Metabarcoding avian diets at airports: implications for birdstrike hazard management planning

    PubMed Central

    2013-01-01

    Background Wildlife collisions with aircraft cost the airline industry billions of dollars per annum and represent a public safety risk. Clearly, adapting aerodrome habitats to become less attractive to hazardous wildlife will reduce the incidence of collisions. Formulating effective habitat management strategies relies on accurate species identification of high-risk species. This can be successfully achieved for all strikes either through morphology and/or DNA-based identifications. Beyond species identification, dietary analysis of birdstrike gut contents can provide valuable intelligence for airport hazard management practices in regards to what food is attracting which species to aerodromes. Here, we present birdstrike identification and dietary data from Perth Airport, Western Australia, an aerodrome that saw approximately 140,000 aircraft movements in 2012. Next-generation high throughput DNA sequencing was employed to investigate 77 carcasses from 16 bird species collected over a 12-month period. Five DNA markers, which broadly characterize vertebrates, invertebrates and plants, were used to target three animal mitochondrial genes (12S rRNA, 16S rRNA, and COI) and a plastid gene (trnL) from DNA extracted from birdstrike carcass gastrointestinal tracts. Results Over 151,000 DNA sequences were generated, filtered and analyzed by a fusion-tag amplicon sequencing approach. Across the 77 carcasses, the most commonly identified vertebrate was Mus musculus (house mouse). Acrididae (grasshoppers) was the most common invertebrate family identified, and Poaceae (grasses) the most commonly identified plant family. The DNA-based dietary data has the potential to provide some key insights into feeding ecologies within and around the aerodrome. Conclusions The data generated here, together with the methodological approach, will greatly assist in the development of hazard management plans and, in combination with existing observational studies, provide an improved way to monitor the effectiveness of mitigation strategies (for example, netting of water, grass type, insecticides and so on) at aerodromes. It is hoped that with the insights provided by dietary data, airports will be able to allocate financial resources to the areas that will achieve the best outcomes for birdstrike reduction. PMID:24330620

  20. Metabarcoding avian diets at airports: implications for birdstrike hazard management planning.

    PubMed

    Coghlan, Megan L; White, Nicole E; Murray, Dáithí C; Houston, Jayne; Rutherford, William; Bellgard, Matthew I; Haile, James; Bunce, Michael

    2013-12-11

    Wildlife collisions with aircraft cost the airline industry billions of dollars per annum and represent a public safety risk. Clearly, adapting aerodrome habitats to become less attractive to hazardous wildlife will reduce the incidence of collisions. Formulating effective habitat management strategies relies on accurate species identification of high-risk species. This can be successfully achieved for all strikes either through morphology and/or DNA-based identifications. Beyond species identification, dietary analysis of birdstrike gut contents can provide valuable intelligence for airport hazard management practices in regards to what food is attracting which species to aerodromes. Here, we present birdstrike identification and dietary data from Perth Airport, Western Australia, an aerodrome that saw approximately 140,000 aircraft movements in 2012. Next-generation high throughput DNA sequencing was employed to investigate 77 carcasses from 16 bird species collected over a 12-month period. Five DNA markers, which broadly characterize vertebrates, invertebrates and plants, were used to target three animal mitochondrial genes (12S rRNA, 16S rRNA, and COI) and a plastid gene (trnL) from DNA extracted from birdstrike carcass gastrointestinal tracts. Over 151,000 DNA sequences were generated, filtered and analyzed by a fusion-tag amplicon sequencing approach. Across the 77 carcasses, the most commonly identified vertebrate was Mus musculus (house mouse). Acrididae (grasshoppers) was the most common invertebrate family identified, and Poaceae (grasses) the most commonly identified plant family. The DNA-based dietary data has the potential to provide some key insights into feeding ecologies within and around the aerodrome. The data generated here, together with the methodological approach, will greatly assist in the development of hazard management plans and, in combination with existing observational studies, provide an improved way to monitor the effectiveness of mitigation strategies (for example, netting of water, grass type, insecticides and so on) at aerodromes. It is hoped that with the insights provided by dietary data, airports will be able to allocate financial resources to the areas that will achieve the best outcomes for birdstrike reduction.

  1. ORNL necessary and sufficient standards for environment, safety, and health. Final report of the Identification Team for other industrial, radiological, and non-radiological hazard facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1998-07-01

    This Necessary and Sufficient (N and S) set of standards is for Other Industrial, Radiological, and Non-Radiological Hazard Facilities at Oak Ridge National Laboratory (ORNL). These facility classifications are based on a laboratory-wide approach to classify facilities by hazard category. An analysis of the hazards associated with the facilities at ORNL was conducted in 1993. To identify standards appropriate for these Other Industrial, Radiological, and Non-Radiological Hazard Facilities, the activities conducted in these facilities were assessed, and the hazards associated with the activities were identified. A preliminary hazards list was distributed to all ORNL organizations. The hazards identified in priormore » hazard analyses are contained in the list, and a category of other was provided in each general hazard area. A workshop to assist organizations in properly completing the list was held. Completed hazard screening lists were compiled for each ORNL division, and a master list was compiled for all Other Industrial, Radiological Hazard, and Non-Radiological facilities and activities. The master list was compared against the results of prior hazard analyses by research and development and environment, safety, and health personnel to ensure completeness. This list, which served as a basis for identifying applicable environment, safety, and health standards, appears in Appendix A.« less

  2. U.S. Geological Survey research in radioactive waste disposal - Fiscal years 1986-1990

    USGS Publications Warehouse

    Trask, N.J.; Stevens, P.R.

    1991-01-01

    The report summarizes progress on geologic and hydrologic research related to the disposal of radioactive wastes. The research efforts are categorized according to whether they are related most directly to: (1) high-level wastes, (2) transuranic wastes, (3) low-level and mixed low-level and hazardous wastes, or (4) uranium mill tailings. Included is research applicable to the identification and geohydrologic characterization of waste-disposal sites, to investigations of specific sites where wastes have been stored, to development of techniques and methods for characterizing disposal sites, and to studies of geologic and hydrologic processes related to the transport and/or retention of waste radionuclides.

  3. An assessment of the crash fire hazard of liquid hydrogen fueled aircraft

    NASA Technical Reports Server (NTRS)

    1982-01-01

    The crash fire hazards of liquid hydrogen fueled aircraft relative to those of mission equivalent aircraft fueled either with conventional fuel or with liquefied methane were evaluated. The aircraft evaluated were based on Lockheed Corporation design for 400 passenger, Mach 0.85, 5500 n. mile aircraft. Four crash scenarios were considered ranging from a minor incident causing some loss of fuel system integrity to a catastrophic crash. Major tasks included a review of hazardous properties of the alternate fuels and of historic crash fire data; a comparative hazard evluation for each of the three fuels under four crash scenarios a comprehensive review and analysis and an identification of areas further development work. The conclusion was that the crash fire hazards are not significantly different when compared in general for the three fuels, although some fuels showed minor advantages in one respect or another.

  4. RCRA Facility Information

    EPA Pesticide Factsheets

    This asset includes hazardous waste information, which is mostly contained in the Resource Conservation and Recovery Act Information (RCRAInfo) System, a national program management and inventory system addressing hazardous waste handlers. In general, all entities that generate, transport, treat, store, and dispose of hazardous waste are required to provide information about their activities to state environmental agencies. These agencies pass on that information to regional and national EPA offices. This regulation is governed by the Resource Conservation and Recovery Act (RCRA), as amended by the Hazardous and Solid Waste Amendments of 1984. RCRAInfo Search can be used to determine identification and location data for specific hazardous waste handlers and to find a wide range of information on treatment, storage, and disposal facilities regarding permit/closure status, compliance with Federal and State regulations, and cleanup activities. Categories of information in this asset include:-- Handlers-- Permit Information-- GIS information on facility location-- Financial Assurance-- Corrective Action-- Compliance Monitoring and Enforcement (CM&E)

  5. Installation-Restoration Program. Preliminary assessment; records search for the 155th Tactical Reconnaissance Group, Nebraska Air National Guard, Lincoln Municipal Airport, Lincoln, Nebraska

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1987-11-01

    The Hazardous Materials Technical Center (HMTC) was retained in May 1986 to conduct the Installation-Restoration Program (IRP) Preliminary Assessment (PA) - Records Search for the 155th Tactical Reconnaissance Group (TRG), Nebraska Air National Guard, Lincoln Municipal Airport, Lincoln, Nebraska (hereinafter referred to as the Base). The Records Search included: an onsite visit including interviews with 19 Base personnel conducted by HMTC personnel on 21-23 May 1986; the acquisition and analysis of pertinent information and records on hazardous materials use and hazardous-waste generation and disposal at the Base; the acquisition and analysis of available geologic, hydrologic, meteorologic, and environmental data frommore » pertinent Federal, State, and local agencies; and the identification of sites on the Base that may be potentially contaminated with hazardous materials/hazardous wastes (HM/HW).« less

  6. Mechanisms of and facility types involved in hazardous materials incidents.

    PubMed Central

    Kales, S N; Polyhronopoulos, G N; Castro, M J; Goldman, R H; Christiani, D C

    1997-01-01

    The purpose of this study was to systematically investigate hazardous materials (hazmat) releases and determine the mechanisms of these accidents, and the industries/activities and chemicals involved. We analyzed responses by Massachusetts' six district hazmat teams from their inception through May 1996. Information from incident reports was extracted onto standard coding sheets. The majority of hazardous materials incidents were caused by spills, leaks, or escapes of hazardous materials (76%) and occurred at fixed facilities (80%). Transportation-related accidents accounted for 20% of incidents. Eleven percent of hazardous materials incidents were at schools or health care facilities. Petroleum-derived fuels were involved in over half of transportation-related accidents, and these accounted for the majority of petroleum fuel releases. Chlorine derivatives were involved in 18% of all accidents and were associated with a wide variety of facility types and activities. In conclusion, systematic study of hazardous materials incidents allows the identification of preventable causes of these incidents. PMID:9300926

  7. Hooked on a feeling: emotional labor as an occupational hazard of the post-industrial age.

    PubMed

    Andrews, Bonnie K; Karcz, Susan; Rosenberg, Beth

    2008-01-01

    Emotional labor is a subtle but serious occupational hazard that is likely to spread rapidly as the global service economy continues to grow. Emotional labor requires more than just acting friendly and being helpful to customers; the worker must manage his or her emotions to create a company-dictated experience for customers. The practice of emotional labor in an unsupportive work environment produces work-related stress, which has a wide range of potentially serious health effects. Though many employers do not acknowledge the existence of emotional labor, it is a real occupational hazard that may generate life-altering effects on physical and emotional health. While no official regulations or identification standards specify emotional labor as an occupational hazard, some guidelines exist regarding its outcome: occupational stress. Emotional labor should be recognized as an occupational hazard by the Occupational Safety and Health Administration (OSHA), but this hazard does not lend itself to regulation through standards. The business culture that demands its performance is questioned.

  8. Defining hazard from the mine worker's perspective

    PubMed Central

    Eiter, B.M.; Kosmoski, C.L.; Connor, B.P.

    2016-01-01

    In the recent past, the mining industry has witnessed a substantial increase in the numbers of fatalities occurring at metal and nonmetal mine sites, but it is unclear why this is occurring. One possible explanation is that workers struggle with identifying worksite hazards and accurately assessing the associated risk. The purpose of this research was to explore this possibility within the mining industry and to more fully understand stone, sand and gravel (SSG) mine workers' thoughts, understandings and perceptions of worksite hazards and risks. Eight mine workers were interviewed and asked to identify common hazards they come across when doing their jobs and to then discuss their perceptions of the risks associated with those identified hazards. The results of this exploratory study indicate the importance of workers' job-related experience as it applies to hazard identification and risk perception, particularly their knowledge of or familiarity with a task, whether or not they had personal control over that task, and the frequency with which they perform that task. PMID:28042176

  9. Evaluation of performance of footwear and flooring systems in combination with personnel using voltage probability analysis

    NASA Astrophysics Data System (ADS)

    Smallwood, Jeremy; Swenson, David E.

    2011-06-01

    Evaluation of electrostatic performance of footwear and flooring in combination is necessary in applications such as electrostatic discharge (ESD) control in electronics manufacture, evaluation of equipment for avoidance of factory process electrostatic ignition risks and avoidance of electrostatic shocks to personnel in working environments. Typical standards use a walking test in which the voltage produced on a subject is evaluated by identification and measurement of the magnitude of the 5 highest "peaks" and "valleys" of the recorded voltage waveform. This method does not lend itself to effective analysis of the risk that the voltage will exceed a hazard threshold. This paper shows the advantages of voltage probability analysis and recommends that the method is adopted for use in future standards.

  10. The use of Matrix-assisted laser desorption ionization-time of flight mass spectrometry in the identification of Francisella tularensis.

    PubMed

    Karatuna, Onur; Celebi, Bekir; Can, Simge; Akyar, Isin; Kilic, Selcuk

    2016-01-15

    Francisella tularensis is the cause of the zoonotic disease tularemia and is classified among highly pathogenic bacteria (HPB) due to its low infection dose and potential for airborne transmission. In the case of HBP, there is a pressing need for rapid, accurate and reliable identification. Phenotypic identification of Francisella species is inappropriate for clinical microbiology laboratories because it is time-consuming, hazardous and subject to variable interpretation. Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) was recently evaluated as a useful tool for the rapid identification of a variety of microorganisms. In this study, we evaluated the use of MALDI-TOF MS for the rapid identification of Francisella tularensis and differentiation of its subspecies. Using national collection of Francisella isolates from the National Tularemia Reference Laboratory (Public Health Institute of Turkey, Ankara), a total of 75 clinical isolates were investigated by species and subspecies-specific polymerase chain reaction (PCR) test and MALDI-TOF MS. All isolates were originally identified as F. tularensis subsp. holarctica due to RD1 subspecies-specific PCR result. For all isolates MALDI-TOF MS provided results in concordance with subspecies-specific PCR analysis. Although PCR-based methods are effective in identifying Francisella species, they are labor-intensive and take longer periods of time to obtain the results when compared with MALDI-TOF MS. MALDI-TOF MS appeared to be a rapid, reliable and cost-effective identification technique for Francisella spp. Shorter analysis time and low cost make this an appealing new option in microbiology laboratories.

  11. The use of matrix-assisted laser desorption ionization-time of flight mass spectrometry in the identification of Francisella tularensis

    PubMed Central

    Karatuna, Onur; Çelebi, Bekir; Can, Simge; Akyar, Işın; Kiliç, Selçuk

    2016-01-01

    Francisella tularensis is the cause of the zoonotic disease tularemia and is classified among highly pathogenic bacteria (HPB) due to its low infection dose and potential for airborne transmission. In the case of HBP, there is a pressing need for rapid, accurate and reliable identification. Phenotypic identification of Francisella species is inappropriate for clinical microbiology laboratories because it is time-consuming, hazardous and subject to variable interpretation. Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) was recently evaluated as a useful tool for the rapid identification of a variety of microorganisms. In this study, we evaluated the use of MALDI-TOF MS for the rapid identification of Francisella tularensis and differentiation of its subspecies. Using national collection of Francisella isolates from the National Tularemia Reference Laboratory (Public Health Institution of Turkey, Ankara), a total of 75 clinical isolates were investigated by species and subspecies-specific polymerase chain reaction (PCR) test and MALDI-TOF MS. All isolates were originally identified as F. tularensis subsp. holarctica according to region of difference 1 (RD1) subspecies-specific PCR results. For all isolates MALDI-TOF MS provided results in concordance with subspecies-specific PCR analysis. Although PCR-based methods are effective in identifying Francisella species, they are labor-intensive and take longer periods of time to obtain the results when compared with MALDI-TOF MS. MALDI-TOF MS appeared to be a rapid, reliable and cost-effective identification technique for Francisella spp. Shorter analysis time and low cost make this an appealing new option in microbiology laboratories. PMID:26773181

  12. Talent in Female Gymnastics: a Survival Analysis Based upon Performance Characteristics.

    PubMed

    Pion, J; Lenoir, M; Vandorpe, B; Segers, V

    2015-11-01

    This study investigated the link between the anthropometric, physical and motor characteristics assessed during talent identification and dropout in young female gymnasts. 3 cohorts of female gymnasts (n=243; 6-9 years) completed a test battery for talent identification. Performance-levels were monitored over 5 years of competition. Kaplan-Meier and Cox Proportional Hazards analyses were conducted to determine the survival rate and the characteristics that influence dropout respectively. Kaplan-Meier analysis indicated that only 18% of the female gymnasts that passed the baseline talent identification test survived at the highest competition level 5 years later. The Cox Proportional Hazards Model indicated that gymnasts with a score in the best quartile for a specific characteristic significantly increased chances of survival by 45-129%. These characteristics being: basic motor skills (129%), shoulder strength (96%), leg strength (53%) and 3 gross motor coordination items (45-73%). These results suggest that tests batteries commonly used for talent identification in young female gymnasts may also provide valuable insights into future dropout. Therefore, multidimensional test batteries deserve a prominent place in the selection process. The individual test results should encourage trainers to invest in an early development of basic physical and motor characteristics to prevent attrition. © Georg Thieme Verlag KG Stuttgart · New York.

  13. European Union's strategy on endocrine disrupting chemicals and the current position of Slovenia.

    PubMed

    Perharič, Lucija; Fatur, Tanja; Drofenik, Jernej

    2016-06-01

    In view of the European Union regulations 1107/2009 and 528/2012, which say that basic substances in plant protection and biocidal products marketed in the European Union (EU) should not have an inherent capacity to cause endocrine disruption, an initiative was started to define scientific criteria for the identification of endocrine disruptors (EDs). The objectives of the EU strategy on EDs are to protect human health and the environment, to assure the functioning of the market, and to provide clear and coherent criteria for the identification of EDs that could have broad application in the EU legislation. Policy issues were to be addressed by the Ad-hoc group of Commission Services, EU Agencies and Member States established in 2010, whereas the scientific issues were to be addressed by the Endocrine Disruptors Expert Advisory Group (ED EAG), established in 2011. The ED EAG adopted the 2002 World Health Organization (WHO) definition of endocrine disruptor and agreed that for its identification it is necessary to produce convincing evidence of a biologically plausible causal link between an adverse effect and endocrine disrupting mode of action. In 2014, the European Commission proposed four ED identification criteria options and three regulatory options, which are now being assessed for socio-economic, environmental, and health impact. Slovenia supports the establishing of identification criteria and favours option 4, according to which ED identification should be based on the WHO definition with the addition of potency as an element of hazard characterisation. As for regulatory options, Slovenia favours the risk-based rather than hazard-based regulation.

  14. Passive RFID Rotation Dimension Reduction via Aggregation

    NASA Astrophysics Data System (ADS)

    Matthews, Eric

    Radio Frequency IDentification (RFID) has applications in object identification, position, and orientation tracking. RFID technology can be applied in hospitals for patient and equipment tracking, stores and warehouses for product tracking, robots for self-localisation, tracking hazardous materials, or locating any other desired object. Efficient and accurate algorithms that perform localisation are required to extract meaningful data beyond simple identification. A Received Signal Strength Indicator (RSSI) is the strength of a received radio frequency signal used to localise passive and active RFID tags. Many factors affect RSSI such as reflections, tag rotation in 3D space, and obstacles blocking line-of-sight. LANDMARC is a statistical method for estimating tag location based on a target tag's similarity to surrounding reference tags. LANDMARC does not take into account the rotation of the target tag. By either aggregating multiple reference tag positions at various rotations, or by determining a rotation value for a newly read tag, we can perform an expected value calculation based on a comparison to the k-most similar training samples via an algorithm called K-Nearest Neighbours (KNN) more accurately. By choosing the average as the aggregation function, we improve the relative accuracy of single-rotation LANDMARC localisation by 10%, and any-rotation localisation by 20%.

  15. Development of a toxicity identification evaluation procedure for characterizing metal toxicity in marine sediments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burgess, R.M.; Cantwell, M.G.; Pelletier, M.C.

    2000-04-01

    A multiagency effort is underway to develop whole sediment toxicity identification evaluation (TIE) methods. Whole sediment TIE methods will be critical tools for characterizing toxicity at hazardous waste sites and in the conduct of environmental risk assessments. The research approach is based on the predominance of three classes of toxicants in sediments: ammonia, nonpolar organic chemicals, and metals. Here the authors describe a procedure for characterizing acute toxicity caused by metals in whole marine sediments. The procedure involves adding a chelating resin to sediments, resulting in the sequestration of bioavailable metal while not stressing testing organisms. Within the testing chambers,more » the presence of resin resulted in statistically significant reductions in the overlying and interstitial water concentrations of five metals (cadmium, copper, nickel, lead, and zinc) generally by factors of 40 and 200. Toxicity to both the amphipod Ampelisca abdita and mysid Americamysis bahia (formerly Mysidopsis bahia) of sediments spiked with the five metals was decreased by approximately a factor of four when resin was present. While very effective at reducing the concentrations and toxicity of metals, the resin has only minor ameliorative effects on the toxicity of ammonia and a representative nonpolar toxicant (Endosulfan). Resin and accumulated metal were easily isolated from the testing system following exposures allowing for the initiation of phase II TIE (identification) procedures. This procedure using the addition of a chelating resin provides an approach for determining the importance of metals to the toxicity of marine sediments. Work is continuing to validate the method with environmentally contaminated sediments.« less

  16. Probabilistic seismic hazard analyses for ground motions and fault displacement at Yucca Mountain, Nevada

    USGS Publications Warehouse

    Stepp, J.C.; Wong, I.; Whitney, J.; Quittmeyer, R.; Abrahamson, N.; Toro, G.; Young, S.R.; Coppersmith, K.; Savy, J.; Sullivan, T.

    2001-01-01

    Probabilistic seismic hazard analyses were conducted to estimate both ground motion and fault displacement hazards at the potential geologic repository for spent nuclear fuel and high-level radioactive waste at Yucca Mountain, Nevada. The study is believed to be the largest and most comprehensive analyses ever conducted for ground-shaking hazard and is a first-of-a-kind assessment of probabilistic fault displacement hazard. The major emphasis of the study was on the quantification of epistemic uncertainty. Six teams of three experts performed seismic source and fault displacement evaluations, and seven individual experts provided ground motion evaluations. State-of-the-practice expert elicitation processes involving structured workshops, consensus identification of parameters and issues to be evaluated, common sharing of data and information, and open exchanges about the basis for preliminary interpretations were implemented. Ground-shaking hazard was computed for a hypothetical rock outcrop at -300 m, the depth of the potential waste emplacement drifts, at the designated design annual exceedance probabilities of 10-3 and 10-4. The fault displacement hazard was calculated at the design annual exceedance probabilities of 10-4 and 10-5.

  17. Grand Junction projects office mixed-waste treatment program, VAC*TRAX mobile treatment unit process hazards analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bloom, R.R.

    1996-04-01

    The objective of this report is to demonstrate that a thorough assessment of the risks associated with the operation of the Rust Geotech patented VAC*TRAX mobile treatment unit (MTU) has been performed and documented. The MTU was developed to treat mixed wastes at the US Department of Energy (DOE) Albuquerque Operations Office sites. The MTU uses an indirectly heated, batch vacuum dryer to thermally desorb organic compounds from mixed wastes. This process hazards analysis evaluated 102 potential hazards. The three significant hazards identified involved the inclusion of oxygen in a process that also included an ignition source and fuel. Changesmore » to the design of the MTU were made concurrent with the hazard identification and analysis; all hazards with initial risk rankings of 1 or 2 were reduced to acceptable risk rankings of 3 or 4. The overall risk to any population group from operation of the MTU was determined to be very low; the MTU is classified as a Radiological Facility with low hazards.« less

  18. Detection of hazardous chemicals using field-portable Raman spectroscopy

    NASA Astrophysics Data System (ADS)

    Wright, Cherylyn W.; Harvey, Scott D.; Wright, Bob W.

    2003-07-01

    A major challenge confronting emergency response, border control, and other security-related functions is the accurate, rapid, and safe identification of potentially hazardous chemicals outside a laboratory environment. Raman spectroscopy is a rapid, non-intrusive technique that can be used to confidently identify many classes of hazardous and potentially explosive compounds based on molecular vibration information. Advances in instrumentation now allow reliable field - portable measurements to be made. Before the Raman technique can be effectively applied and be accepted within the scientific community, realistic studies must be performed to develop methods, define limitations, and rigorously evaluate its effectiveness. Examples of a variety of chemicals (including neat and diluted chemical warfare [CW] agents, a CW agent precursor, a biological warfare (BW)-related compound, an illicit drug, and explosives) identified using Raman spectroscopy in various types of containers and on surfaces are given, as well as results from a blind field test of 29 unknown samples which included CW agent precursors and/or degradation products, solvents associated with CW agent production, pesticides, explosives, and BW toxins (mostly mycotoxins). Additionally, results of experimental studies to evaluate the analysis of flammable organic solvents, propellants, military explosives, mixtures containing military explosives, shock-sensitive explosives, and gun powders are described with safety guidelines. Spectral masks for screening unknown samples for explosives and nerve agents are given.

  19. Critical control points of complementary food preparation and handling in eastern Nigeria.

    PubMed Central

    Ehiri, J. E.; Azubuike, M. C.; Ubbaonu, C. N.; Anyanwu, E. C.; Ibe, K. M.; Ogbonna, M. O.

    2001-01-01

    OBJECTIVE: To investigate microbial contamination and critical control points (CCPs) in the preparation and handling of complementary foods in 120 households in Imo state, Nigeria. METHODS: The Hazard Analysis Critical Control Point (HACCP) approach was used to investigate processes and procedures that contributed to microbial contamination, growth and survival, and to identify points where controls could be applied to prevent or eliminate these microbiological hazards or reduce them to acceptable levels. Food samples were collected and tested microbiologically at different stages of preparation and handling. FINDINGS: During cooking, all foods attained temperatures capable of destroying vegetative forms of food-borne pathogens. However, the risk of contamination increased by storage of food at ambient temperature, by using insufficiently high temperatures to reheat the food, and by adding contaminated ingredients such as dried ground crayfish and soybean powder at stages where no further heat treatment was applied. The purchasing of contaminated raw foodstuffs and ingredients, particularly raw akamu, from vendors in open markets is also a CCP. CONCLUSION: Although an unsafe environment poses many hazards for children's food, the hygienic quality of prepared food can be assured if basic food safety principles are observed. When many factors contribute to food contamination, identification of CCPs becomes particularly important and can facilitate appropriate targeting of resources and prevention efforts. PMID:11417038

  20. Volcanic hazard communication using maps: an evaluation of their effectiveness

    NASA Astrophysics Data System (ADS)

    Haynes, Katharine; Barclay, Jenni; Pidgeon, Nick

    2007-11-01

    Hazard maps are considered essential tools in the communication of volcanic risk between scientists, the local authorities and the public. This study investigates the efficacy of such maps for the volcanic island of Montserrat in the West Indies using both quantitative and qualitative research techniques. Normal plan view maps, which have been used on the island over the last 10 years of the crisis, are evaluated against specially produced three-dimensional (3D) maps and perspective photographs. Thirty-two demographically representative respondents of mixed backgrounds, sex, education and location were interviewed and asked to complete a range of tasks and identification on the maps and photographs. The overall results show that ordinary people have problems interpreting their environment as a mapped representation. We found respondents’ ability to locate and orientate themselves as well as convey information relating to volcanic hazards was improved when using aerial photographs rather than traditional plan view contour maps. There was a slight improvement in the use of the 3D maps, especially in terms of topographic recognition. However, the most striking increase in effectiveness was found with the perspective photographs, which enabled people to identify features and their orientation much more readily. For Montserrat it appears that well labelled aerial and perspective photographs are the most effective geo-spatial method of communicating volcanic risks.

  1. Evaluation of protein safety in the context of agricultural biotechnology.

    PubMed

    Delaney, Bryan; Astwood, James D; Cunny, Helen; Conn, Robin Eichen; Herouet-Guicheney, Corinne; Macintosh, Susan; Meyer, Linda S; Privalle, Laura; Gao, Yong; Mattsson, Joel; Levine, Marci

    2008-05-01

    One component of the safety assessment of agricultural products produced through biotechnology is evaluation of the safety of newly expressed proteins. The ILSI International Food Biotechnology Committee has developed a scientifically based two-tiered, weight-of-evidence strategy to assess the safety of novel proteins used in the context of agricultural biotechnology. Recommendations draw upon knowledge of the biological and chemical characteristics of proteins and testing methods for evaluating potential intrinsic hazards of chemicals. Tier I (potential hazard identification) includes an assessment of the biological function or mode of action and intended application of the protein, history of safe use, comparison of the amino acid sequence of the protein to other proteins, as well as the biochemical and physico-chemical properties of the proteins. Studies outlined in Tier II (hazard characterization) are conducted when the results from Tier I are not sufficient to allow a determination of safety (reasonable certainty of no harm) on a case-by-case basis. These studies may include acute and repeated dose toxicology studies and hypothesis-based testing. The application of these guidelines is presented using examples of transgenic proteins applied for agricultural input and output traits in genetically modified crops along with recommendations for future research considerations related to protein safety assessment.

  2. Recommended approaches to the scientific evaluation of ...

    EPA Pesticide Factsheets

    A SETAC Pellston Workshop™ ?‘Environmental Hazard and Risk Assessment Approaches for Endocrine-Active Substances (EHRA)’ was held from 31st January to 5th February 2016 in Pensacola, Florida, USA. The primary aim of the workshop was to provide objective advice, based on current scientific understanding, to regulators and policy makers, whether in industry, government or academia. The aim being to make considered, informed decisions on whether to select an environmental hazard- or a risk-based approach for regulating a given endocrine-disrupting substance (EDS) under review. The workshop additionally considered recent developments in the identification of EDS. Case studies were undertaken on six endocrine active substances (EAS not necessarily proven EDS), that are representative of a range of endocrine system perturbations and considered to be data-rich in relevant information at multiple biological levels of organisation for one or more ecologically-relevant taxa. The substances selected were 17á-ethinylestradiol, perchlorate, propiconazole, 17â-trenbolone, tributyltin and vinclozolin. The six case studies were not comprehensive safety evaluations, but provided the foundations for clarifying key issues and procedures that should be considered when assessing the environmental hazards and risks of EAS and EDS. The workshop also highlighted areas of scientific uncertainty, and made specific recommendations for research and methods-development to resolve

  3. Hazard identification, dose-response and environmental characteristics of stachybotryotoxins and other health-related products from Stachybotrys.

    PubMed

    Lai, K M

    2006-03-01

    An extensive growth of Stachybotrys in water-damaged buildings is of great public health concern. It is inconclusive whether Stachybotrys is responsible for the reported health effects on the occupants in these contaminated environments. However, based on the veterinary, occupational and laboratory toxicity studies, it is reasonable to project that Stachybotrys can cause adverse health responses once the toxic level of the corresponding agents reached the target systems. In order to assess the risk to occupants in contaminated buildings, it is essential to outline and collect information for risk assessment. This review paper presents the current information in the format of hazard identification, dose-response and environmental characteristics and aims to discuss existing information with researchers and risk assessors and help to conduct risk characterization under different indoor conditions.

  4. Effects of organizational safety on employees' proactivity safety behaviors and occupational health and safety management systems in Chinese high-risk small-scale enterprises.

    PubMed

    Mei, Qiang; Wang, Qiwei; Liu, Suxia; Zhou, Qiaomei; Zhang, Jingjing

    2018-06-07

    Based on the characteristics of small-scale enterprises, the improvement of occupational health and safety management systems (OHS MS) needs an effective intervention. This study proposed a structural equation model and examined the relationships of perceived organization support for safety (POSS), person-organization safety fit (POSF) and proactivity safety behaviors with safety management, safety procedures and safety hazards identification. Data were collected from 503 employees of 105 Chinese high-risk small-scale enterprises over 6 months. The results showed that both POSS and POSF were positively related to improvement in safety management, safety procedures and safety hazards identification through proactivity safety behaviors. Our findings provide a new perspective on organizational safety for improving OHS MS for small-scale enterprises and extend the application of proactivity safety behaviors.

  5. Implementation of health and safety management system to reduce hazardous potential in PT.XYZ Indonesia

    NASA Astrophysics Data System (ADS)

    Widodo, L.; Adianto; Sartika, D. I.

    2017-12-01

    PT. XYZ is a large automotive manufacturing company that manufacture, assemble as well as a car exporter. The other products are spare parts, jig and dies. PT. XYZ has long been implementing the Occupational Safety and Health Management System (OSHMS) to reduce the potential hazards that cause work accidents. However, this does not mean that OSHMS that has been implemented does not need to be upgraded and improved. This is due to the potential danger caused by work is quite high. This research was conducted in Sunter 2 Plant where its production activities have a high level of potential hazard. Based on Hazard Identification risk assessment, Risk Assessment, and Risk Control (HIRARC) found 10 potential hazards in Plant Stamping Production, consisting of 4 very high risk potential hazards (E), 5 high risk potential hazards (H), and 1 moderate risk potential hazard (M). While in Plant Casting Production found 22 potential hazards findings consist of 7 very high risk potential hazards (E), 12 high risk potential hazards (H), and 3 medium risk potential hazards (M). Based on the result of Fault Tree Analysis (FTA), the main priority is the high risk potential hazards (H) and very high risk potential hazards (E). The proposed improvement are to make the visual display of the importance of always using the correct Personal Protective Equipment (PPE), establishing good working procedures, conducting OSH training for workers on a regular basis, and continuing to conduct safety campaigns.

  6. Computer Model Locates Environmental Hazards

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Catherine Huybrechts Burton founded San Francisco-based Endpoint Environmental (2E) LLC in 2005 while she was a student intern and project manager at Ames Research Center with NASA's DEVELOP program. The 2E team created the Tire Identification from Reflectance model, which algorithmically processes satellite images using turnkey technology to retain only the darkest parts of an image. This model allows 2E to locate piles of rubber tires, which often are stockpiled illegally and cause hazardous environmental conditions and fires.

  7. Preliminary Assessment McGhee - Tyson ANGB, McGhee - Tyson Municipal Airport, Knoxville, Tennessee

    DTIC Science & Technology

    1988-06-01

    and assessment of sites on the Base which may have been contaminated with hazardous materials/hazardous waste. B. MAJOR FINDINGS The Air National Guard...identification of eleven (11) sites (see Figure ES.I). Of this total, seven exhibit the potential for contaminant presence and possible migration. The remaining...four sites pose no potential threat to human and environmental receptors from either surface or ground water contamination . I I ES-i Source: McGhee

  8. Rapid screening and identification of improvised explosive and hazardous precursor materials by Raman spectroscopy

    NASA Astrophysics Data System (ADS)

    Stokes, Robert J.; Smith, W. Ewen; Foulger, Brian; Lewis, Colin

    2008-10-01

    A low cost technique is reported for the rapid screening of containers for materials that potentially could be used for terrorist activities. For peroxide based samples it is demonstrated that full characterisation can be achieved in a continuous curve fitting monitoring mode acquiring up to 10 spectra per second. This clearly demonstrates the potential for a Raman based method to be incorporated into a check-point whilst retaining fast throughput. A number of precursor compounds to nerve agents and peroxide and nitrate based improvised explosive materials have been studied. The potential strengths and weaknesses of using Raman for multiple target identification are discussed with regard to the common vibrations associated with each group of agents. Within this context we also introduce the use of fast Raman line mapping into the trace analysis of multiple component targets. The method presented is suited to volatile or light sensitive samples (such as derived peroxides) and can be employed on a variety of surfaces. As speed and throughput are traded against spectral bandwidth categorising threat compounds into groups based on common functionalities allows the full potential for multiplexed targeting to be realised.

  9. Identification of Critical Vulnerable Areas During a Typhoon Haiyan Event in the Metro Manila Area Using Storm Surge Hazard Maps

    NASA Astrophysics Data System (ADS)

    Briones, J. B. L. T.; Puno, J. V.; Lapidez, J. P. B.; Muldong, T. M. M.; Ramos, M. M.; Caro, C. V.; Ladiero, C.; Bahala, M. A.; Suarez, J. K. B.; Santiago, J. T.

    2014-12-01

    Sudden rises in sea water over and above astronomical tides due to an approaching storm are known as storm surges. The development of an early warning system for storm surges is imperative, due to the high threat level of these events; Typhoon Haiyan in 08 November 2013 generated storm surges that caused casualties of over 6,000. Under the Department of Science and Technology, the Nationwide Operational Assessment of Hazards (DOST - Project NOAH) was tasked to generate storm surge hazard maps for all the coastal areas in the Philippines. The objective of this paper is to create guidelines on how to utilize the storm surge hazard map as a tool for planning and disaster mitigation. This study uses the case of the hypothetical situation in which a tropical storm with an intensity similar to Typhoon Haiyan hits Metro Manila. This site was chosen for various reasons, among them the economic, political, and cultural importance of Metro Manila as the location of the capital of the Philippines and the coastal bay length of the area. The concentration of residential areas and other establishments were also taken into account. Using the Japan Meteorology Association (JMA) Storm Surge Model, FLO-2D flood modelling software and the application of other GIS technology, the impact of Haiyan-strength typhoon passing through Manila was analysed. We were able to identify the population affected, number of affected critical facilities under each storm surge hazard level, and possible evacuation sites. The results of the study can be used as the basis of policies involving disaster response and mitigation by city authorities. The methods used by the study can be used as a replicable framework for the analysis of other sites in the Philippines.

  10. Tourism hazard potentials in Mount Merapi: how to deal with the risk

    NASA Astrophysics Data System (ADS)

    Muthiah, J.; Muntasib, E. K. S. H.; Meilani, R.

    2018-05-01

    Mount Merapi as one of the most popular natural tourism destination in Indonesia, indicated as disaster prone area. Hazard management is required to ensure visitors safety. Hazard identification and mapping are prerequisite in developing proper hazard management recommendation. This study aimed to map hazard potentials’ geographical positions obtained with geographical positioning system and to identify the hazard management being implemented. Data collection was carried out in Mei – June 2017 through observation and interview. Hiking trail and Lava tour area was selected as the study site, since the sites are the main areas for tourism activities in Mount Merapi. The type of hazards found in the area included lava, tephra, eruption cloud, ash, earthquake, land slide, extreme weather, slope and loose rock. Early warning system had been developed in this area, however the mechanism to regulate tourism activities still had to be improved. Local tourism entrepreneurs should be involved in the network of early warning system stakeholders to ensure tourist safety, and their capacity should be improved in order to be able to perform the measures needed for handling accident and disaster occurrences. Interpretive media explaining hazard potentials may be used to improve visitors’ awareness and ability to cope with the risk.

  11. Characteristics, Properties and Analytical Methods of Amoxicillin: A Review with Green Approach.

    PubMed

    de Marco, Bianca Aparecida; Natori, Jéssica Sayuri Hisano; Fanelli, Stefany; Tótoli, Eliane Gandolpho; Salgado, Hérida Regina Nunes

    2017-05-04

    Bacterial infections are the second leading cause of global mortality. Considering this fact, it is extremely important studying the antimicrobial agents. Amoxicillin is an antimicrobial agent that belongs to the class of penicillins; it has bactericidal activity and is widely used in the Brazilian health system. In literature, some analytical methods are found for the identification and quantification of this penicillin, which are essential for its quality control, which ensures maintaining the product characteristics, therapeutic efficacy and patient's safety. Thus, this study presents a brief literature review on amoxicillin and the analytical methods developed for the analysis of this drug in official and scientific papers. The major analytical methods found were high-performance liquid chromatography (HPLC), ultra-performance liquid chromatography (U-HPLC), capillary electrophoresis and iodometry and diffuse reflectance infrared Fourier transform. It is essential to note that most of the developed methods used toxic and hazardous solvents, which makes necessary industries and researchers choose to develop environmental-friendly techniques to provide enhanced benefits to environment and staff.

  12. Development of a LIBS assay for the detection of Salmonella enterica serovar Typhimurium from food.

    PubMed

    Barnett, Cleon; Bell, Courtneé; Vig, Komal; Akpovo, A C; Johnson, Lewis; Pillai, Shreekumar; Singh, Shree

    2011-07-01

    Laser-induced breakdown spectroscopy (LIBS) is used for the identification of the presence of hazardous bacteria in food. In this study, our main focus was centered on the identification of S. enterica serovar Typhimurium, a Gram-negative foodborne pathogen, in various liquids such as milk, chicken broth, and brain heart infusion due to the infection being most prevalent in raw meat and dairy products. A Nd:YAG laser of operating wavelength 266 nm was used to obtain the spectra from the artificially inoculated liquid samples. A series of experiments were performed to determine the effectiveness of LIBS to discriminate the bacteria from the background liquids. These results are compared with competing modern molecular methods of detection which include polymerase chain reaction (PCR) and quantitative real-time PCR. In addition to analyzing S. enterica serovar Typhimurium, another common Gram-negative, Escherichia coli, as well as Gram-positive pathogen, Staphlycoccus auerus, were used to determine the specificity of the LIBS technique.

  13. The diagnosis of Echinococcus granulosus in dogs.

    PubMed

    Varcasia, A; Garippa, G; Scala, A

    2004-12-01

    The problem of diagnosing Echinococcus granulosus in dogs has still only been partially resolved, even after the advent of biotechnology. The eggs of taeniid Cestoda are extremely similar, and thus identification by microscopic examination of the faeces is risky and non-specific. For this reason, Echinococcus granulosus was traditionally diagnosed in dogs ante mortem after an arecoline hydrobromate purge. The faeces were examined macro and microscopically to establish if the adult tapeworm or its proglottids were present. Although this method is 100% specific, it is bio-hazardous and time-consuming, requires trained personnel, and its sensitivity varies. In the 1990s copro-antigens were discovered and characterised. These are released by the adult worm in the faeces. This made it possible to use enzyme-linked immune-adsorbent assay (ELISA) for in vitam diagnosis of Echinococcus granulosus. In recent years several PCR protocols have been published on the identification of Echinococcus granulosus DNA from eggs or from adult parasites and new ways of diagnosing this cestode have been developed.

  14. A discussion of occupational health and safety management for the catering industry in China.

    PubMed

    Qiang, Chen; Chow, Wan Ki

    2007-01-01

    The catering industry is developing rapidly in China. Statistics in 2002 indicated that there were over 3.5 million dining places in China, hiring over 18 million people. However, the accident rate was high. Occupational health and safety (OHS) has to be watched more carefully. It is proposed to develop an OHS management system for the catering industry and to integrate it with an ongoing management system by referring to OHSAS 18001:1999. The first step is risk identification and evaluating the major factors concerned by referring to the codes in China, the list of occupational diseases, operation rules, requirements of the law, and records of past incidents. The technological aspect has to be considered in working out the safety strategies. This includes technical measures in accident prevention at the workplace. The kitchen is the main area to be focused on. Methods for hazard identification and risk assessment of dangerous factors in kitchens are proposed in this paper.

  15. Surveillance and Molecular Identification of Acanthamoeba and Naegleria Species in Two Swimming Pools in Alexandria University, Egypt

    PubMed Central

    AL-HERRAWY, Ahmad Z.; KHALIL, Mahmoud I.; EL-SHERIF, Soheir S.; OMAR, Fatima A. E.; LOTFY, Wael M.

    2017-01-01

    Background: Swimming in contaminated water was reported to be associated with Acanthamoeba and N. fowleri human infections. The present study was carried out with the aim of isolation and identification of the different species of Acanthamoeba and Naegleria from two swimming pools in Alexandria University. Methods: Samples were collected from the swimming pools of Alexandria University Stadium and Faculty of Agriculture-Alexandria University during the period from May 2012 to April 2013. Results: Free-living amoebae were prevalent in the collected samples. Molecular characterization confirmed the identity of ten Acanthamoeba isolates and seven Naegleria isolates. Acanthamoeba T3, T4, T5, T11 and T15 genotypes were identified. Acanthamoeba T4 was the most prevalent genotype. Conclusion: The relatively high prevalence of Acanthamoeba, especially genotype T4, indicates the presence of a health hazard to swimmers particularly those wearing contact lenses. Naegleria fowleri was not found during the present study. PMID:28761479

  16. Application of quality risk management to set viable environmental monitoring frequencies in biotechnology processing and support areas.

    PubMed

    Sandle, Tim

    2012-01-01

    Environmental monitoring programs are essential for pharmaceutical facilities in order to assess the level of environmental control. For biotechnology facilities there is little advice as to the frequency at which viable environmental monitoring should be conducted. This paper outlines an approach, based on the principles of quality risk management, for the development of a framework from which monitoring frequencies can be determined. This involved the identification of common hazards and the evaluation those hazards in terms of the severity of contamination and the probability of contamination occurring. These elements of risk were evaluated for different cleanrooms and the relative risks ranked. Once the risk scores were calculated, the methods for detecting risks within the cleanrooms were assessed. Risk filtering was then used to group different cleanrooms based on their relative risks and detection methods against predetermined monitoring frequencies. Through use of case study examples, the paper presents the model and describes how appropriate frequencies for the environmental monitoring of cleanrooms can be set. Cleanrooms in which biotechnology pharmaceutical processing takes place are subject to environmental monitoring. The frequency at which such monitoring should be performed can be difficult to determine. This paper uses quality risk assessment methods to construct a framework for determining monitoring frequencies and illustrates the suitability of the framework through a case study.

  17. Alternatives for skin sensitisation: Hazard identification and potency categorisation: Report from an EPAA/CEFIC LRI/Cosmetics Europe cross sector workshop, ECHA Helsinki, April 23rd and 24th 2015.

    PubMed

    Basketter, David; Ashikaga, Takao; Casati, Silvia; Hubesch, Bruno; Jaworska, Joanna; de Knecht, Joop; Landsiedel, Robert; Manou, Irene; Mehling, Annette; Petersohn, Dirk; Rorije, Emiel; Rossi, Laura H; Steiling, Winfried; Teissier, Silvia; Worth, Andrew

    2015-11-01

    In the two years since the last workshop report, the environment surrounding the prediction of skin sensitisation hazards has experienced major change. Validated non-animal tests are now OECD Test Guidelines. Accordingly, the recent cross sector workshop focused on how to use in vitro data for regulatory decision-making. After a review of general approaches and six case studies, there was broad consensus that a simple, transparent stepwise process involving non-animal methods was an opportunity waiting to be seized. There was also strong feeling the approach should not be so rigidly defined that assay variations/additional tests are locked out. Neither should it preclude more complex integrated approaches being used for other purposes, e.g. potency estimation. All agreed the ultimate goal is a high level of protection of human health. Thus, experience in the population will be the final arbiter of whether toxicological predictions are fit for purpose. Central to this is the reflection that none of the existing animal assays is perfect; the non-animal methods should not be expected to be so either, but by integrated use of methods and all other relevant information, including clinical feedback, we have the opportunity to continue to improve toxicology whilst avoiding animal use. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. 44 CFR 65.3 - Requirement to submit new technical data.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... available, a community shall notify the Administrator of the changes by submitting technical or scientific... IDENTIFICATION AND MAPPING OF SPECIAL HAZARD AREAS § 65.3 Requirement to submit new technical data. A community's...

  19. INHALATION EXPOSURE-RESPONSE METHODOLOGY

    EPA Science Inventory

    The Inhalation Exposure-Response Analysis Methodology Document is expected to provide guidance on the development of the basic toxicological foundations for deriving reference values for human health effects, focusing on the hazard identification and dose-response aspects of the ...

  20. Identification, prediction, and mitigation of sinkhole hazards in evaporite karst areas

    USGS Publications Warehouse

    Gutierrez, F.; Cooper, A.H.; Johnson, K.S.

    2008-01-01

    Sinkholes usually have a higher probability of occurrence and a greater genetic diversity in evaporite terrains than in carbonate karst areas. This is because evaporites have a higher solubility and, commonly, a lower mechanical strength. Subsidence damage resulting from evaporite dissolution generates substantial losses throughout the world, but the causes are only well understood in a few areas. To deal with these hazards, a phased approach is needed for sinkhole identification, investigation, prediction, and mitigation. Identification techniques include field surveys and geomorphological mapping combined with accounts from local people and historical sources. Detailed sinkhole maps can be constructed from sequential historical maps, recent topographical maps, and digital elevation models (DEMs) complemented with building-damage surveying, remote sensing, and high-resolution geodetic surveys. On a more detailed level, information from exposed paleosubsidence features (paleokarst), speleological explorations, geophysical investigations, trenching, dating techniques, and boreholes may help in investigating dissolution and subsidence features. Information on the hydrogeological pathways including caves, springs, and swallow holes are particularly important especially when corroborated by tracer tests. These diverse data sources make a valuable database-the karst inventory. From this dataset, sinkhole susceptibility zonations (relative probability) may be produced based on the spatial distribution of the features and good knowledge of the local geology. Sinkhole distribution can be investigated by spatial distribution analysis techniques including studies of preferential elongation, alignment, and nearest neighbor analysis. More objective susceptibility models may be obtained by analyzing the statistical relationships between the known sinkholes and the conditioning factors. Chronological information on sinkhole formation is required to estimate the probability of occurrence of sinkholes (number of sinkholes/km2 year). Such spatial and temporal predictions, frequently derived from limited records and based on the assumption that past sinkhole activity may be extrapolated to the future, are non-corroborated hypotheses. Validation methods allow us to assess the predictive capability of the susceptibility maps and to transform them into probability maps. Avoiding the most hazardous areas by preventive planning is the safest strategy for development in sinkhole-prone areas. Corrective measures could be applied to reduce the dissolution activity and subsidence processes. A more practical solution for safe development is to reduce the vulnerability of the structures by using subsidence-proof designs. ?? 2007 Springer-Verlag.

  1. Seeing Eye Drones: How The DOD Can Transform CBM And Disaster Response In The Homeland

    DTIC Science & Technology

    2016-12-01

    thesis explores the possibility of integrating small unmanned aircraft systems (sUAS) with video capability and CBRN detection and identification sensors...small, unmanned aircraft systems (sUAS) with video capability and CBRN detection and identification sensors for use by National Guard civil support...CBRN) and hazardous material (HAZMAT) materials, as well as providing video to the incident commander. One of the primary benefits of providing

  2. Remotely Sensed Quantitative Drought Risk Assessment in Vulnerable Agroecosystems

    NASA Astrophysics Data System (ADS)

    Dalezios, N. R.; Blanta, A.; Spyropoulos, N. V.

    2012-04-01

    Hazard may be defined as a potential threat to humans and their welfare and risk (or consequence) as the probability of a hazard occurring and creating loss. Drought is considered as one of the major natural hazards with significant impact to agriculture, environment, economy and society. This paper deals with drought risk assessment, which the first step designed to find out what the problems are and comprises three distinct steps, namely risk identification, risk management which is not covered in this paper, there should be a fourth step to address the need for feedback and to take post-audits of all risk assessment exercises. In particular, quantitative drought risk assessment is attempted by using statistical methods. For the qualification of drought, the Reconnaissance Drought Index (RDI) is employed, which is a new index based on hydrometeorological parameters, such as precipitation and potential evapotranspiration. The remotely sensed estimation of RDI is based on NOA-AVHRR satellite data for a period of 20 years (1981-2001). The study area is Thessaly, central Greece, which is a drought-prone agricultural region characterized by vulnerable agriculture. Specifically, the undertaken drought risk assessment processes are specified as follows: 1. Risk identification: This step involves drought quantification and monitoring based on remotely sensed RDI and extraction of several features such as severity, duration, areal extent, onset and end time. Moreover, it involves a drought early warning system based on the above parameters. 2. Risk estimation: This step includes an analysis of drought severity, frequency and their relationships. 3. Risk evaluation: This step covers drought evaluation based on analysis of RDI images before and after each drought episode, which usually lasts one hydrological year (12month). The results of these three-step drought assessment processes are considered quite satisfactory in a drought-prone region such as Thessaly in central Greece. Moreover, remote sensing has proven very effective in delineating spatial variability and features in drought monitoring and assessment.

  3. Inception horizon concept as a basis for sinkhole hazard mapping

    NASA Astrophysics Data System (ADS)

    Vouillamoz, J.; Jeannin, P.-Y.; Kopp, L.; Chantry, R.

    2012-04-01

    The office for natural hazards of the Vaud canton (Switzerland) is interested for a pragmatic approach to map sinkhole hazard in karst areas. A team was created by merging resources from a geoengineering company (CSD) and a karst specialist (SISKA). Large areas in Vaud territory are limestone karst in which the collapse hazard is essentially related to the collapse of soft-rocks covering underground cavities, rather than the collapse of limestone roofs or underground chambers. This statement is probably not valid for cases in gypsum and salt. Thus, for limestone areas, zones of highest danger are voids covered by a thin layer of soft-sediments. The spatial distributions of void and cover-thickness should therefore be used for the hazard assessment. VOID ASSESSMENT Inception features (IF) are millimetre to decimetre thick planes (mainly bedding but also fractures) showing a mineralogical, a granulometrical or a physical contrast with the surrounding formation that make them especially susceptible to karst development (FILIPPONI ET AL., 2009). The analysis of more than 1500 km of cave passage showed that karst conduits are mainly developed along such discrete layers within a limestone series. The so-called Karst-ALEA method (FILIPPONI ET AL., 2011) is based on this concept and aims at assessing the probability of karst conduit occurrences in the drilling of a tunnel. This approach requires as entries the identification of inception features (IF), the recognition of paleo-water-table (PWT), and their respective spatial distribution in a 3D geological model. We suggest the Karst-ALEA method to be adjusted in order to assess the void distribution in subsurface as a basis for sinkhole hazard mapping. Inception features (horizons or fractures) and paleo-water-tables (PWT) have to be first identified using visible caves and dolines. These features should then be introduced into a 3D geological model. Intersections of HI and PWT located close to landsurface are areas with a high probability of karst occurrence. ASSESSMENT OF THE SOFT-SEDIMENT COVER Classical geological investigations (mapping, DEM analysis, drilling, etc.) are used to establish a map of the thickness of soft-sediment on top of the limestone. This can also be included in the 3D model. The combination of the void and soft-sediment information in the 3D model makes it possible to derive the sinkhole hazard map. This is currently being developed and applied in the Vaud canton and first results will be presented. BIBLIOGRAPHY FILIPPONI, M., JEANNIN, P. & TACHER, L. (2009): Evidence of inception horizons in karst conduit networks. Geomorphology, 106, 86-99. FILIPPONI, M., SCHMASSMANN, S., JEANNIN, P. Y. & PARRIAUX, A. (2011): Karst - ALEA - Method a risk assessment method of karst for tunnel projects: Application to the Tunnel of Flims (GR, Switzerland). Proc. 9th conference on limestone hydrogeology. Besançon, France. p. 181-184.

  4. The Alcohol Use Disorders Identification Scale (AUDIT) normative scores for a multiracial sample of Rhodes University residence students.

    PubMed

    Young, Charles; Mayson, Tamara

    2010-06-01

    The objective of this research is to obtain accurate drinking norms for students living in the university residences in preparation for future social norms interventions that would allow individual students to compare their drinking to an appropriate reference group. Random cluster sampling was used to obtain data from 318 residence students who completed the Alcohol Use Disorders Identification Test (AUDIT), a brief, reliable and valid screening measure designed by the World Health Organisation (Babor et al. 2001). The Cronbach alpha coefficient of 0.83 reported for this multicultural sample is high, suggesting that the AUDIT may be reliably used in this and similar contexts. Normative scores are reported in the form of percentiles. Comparisons between the portions of students drinking safely and hazardously according to race and gender indicate that while male students are drinking no more hazardously than female students, white students drink far more hazardously than black students. These differences suggest that both race- and gender-specific norms would be essential for an effective social norms intervention in this multicultural South African context. Finally, the racialised drinking patterns might reflect an informal segregation of social space at Rhodes University.

  5. Techniques for development of safety-related software for surgical robots.

    PubMed

    Varley, P

    1999-12-01

    Regulatory bodies require evidence that software controlling potentially hazardous devices is developed to good manufacturing practices. Effective techniques used in other industries assume long timescales and high staffing levels and can be unsuitable for use without adaptation in developing electronic healthcare devices. This paper discusses a set of techniques used in practice to develop software for a particular innovative medical product, an endoscopic camera manipulator. These techniques include identification of potential hazards and tracing their mitigating factors through the project lifecycle.

  6. Directory of aerospace safety specialized information sources, volume 2

    NASA Technical Reports Server (NTRS)

    Rubinstein, R. I.; Pinto, J. J.; Meschkow, S. Z.

    1976-01-01

    A handbook of organizations and experts in specific and well-defined areas of safety technology is presented. It is designed for the safety specialist as an aid for locating both information sources and individual points of contact (experts) in engineering related fields. The file covers sources of data in aerospace design, tests, and operations, as well as information on hazard and failure cause identification, accident analysis, and materials characteristics. Other related areas include the handling and transportation of hazardous chemicals, radioactive isotopes, and liquified natural gases.

  7. OSL Dating and GPR Mapping of Palaeotsunami Inundation: A 4000-Year History of Indian Ocean Tsunamis as recorded in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Premasiri, Ranjith; Styles, Peter; Shrira, Victor; Cassidy, Nigel; Schwenninger, Jean-Luc

    2015-12-01

    To evaluate and mitigate tsunami hazard, as long as possible records of inundations and dates of past events are needed. Coastal sediments deposited by tsunamis (tsunamites) can potentially provide this information. However, of the three key elements needed for reconstruction of palaeotsunamis (identification of sediments, dating and finding the inundation distance) the latter remains the most difficult. The existing methods for estimating the extent of a palaeotsunami inundation rely on extensive excavation, which is not always possible. Here, by analysing tsunamites from Sri Lanka identified using sedimentological and paleontological characteristics, we show that their internal dielectric properties differ significantly from surrounding sediments. The significant difference in the value of dielectric constant of the otherwise almost indistinguishable sediments is due to higher water content of tsunamites. The contrasts were found to be sharp and not to erode over thousands of years; they cause sizeable electromagnetic wave reflections from tsunamite sediments, which permit the use of ground-penetrating radar (GPR) to trace their extent and morphology. In this study of the 2004 Boxing Day Indian Ocean tsunami, we use GPR in two locations in Sri Lanka to trace four identified major palaeotsunami deposits for at least 400 m inland (investigation inland was constrained by inaccessible security zones). The subsurface extent of tsunamites (not available without extensive excavation) provides a good proxy for inundation. The deposits were dated using the established method of optically stimulated luminescence (OSL). This dating, partly corroborated by available historical records and independent studies, contributes to the global picture of tsunami hazard in the Indian Ocean. The proposed method of combined GPR/OSL-based reconstruction of palaeotsunami deposits enables estimates of inundation, recurrence and, therefore, tsunami hazard for any sandy coast with identifiable tsunamite deposits. The method could be also used for anchoring and synchronizing chronologies of ancient civilisations adjacent to the ocean shores.

  8. A Graph-Centric Approach for Metagenome-Guided Peptide and Protein Identification in Metaproteomics

    PubMed Central

    Tang, Haixu; Li, Sujun; Ye, Yuzhen

    2016-01-01

    Metaproteomic studies adopt the common bottom-up proteomics approach to investigate the protein composition and the dynamics of protein expression in microbial communities. When matched metagenomic and/or metatranscriptomic data of the microbial communities are available, metaproteomic data analyses often employ a metagenome-guided approach, in which complete or fragmental protein-coding genes are first directly predicted from metagenomic (and/or metatranscriptomic) sequences or from their assemblies, and the resulting protein sequences are then used as the reference database for peptide/protein identification from MS/MS spectra. This approach is often limited because protein coding genes predicted from metagenomes are incomplete and fragmental. In this paper, we present a graph-centric approach to improving metagenome-guided peptide and protein identification in metaproteomics. Our method exploits the de Bruijn graph structure reported by metagenome assembly algorithms to generate a comprehensive database of protein sequences encoded in the community. We tested our method using several public metaproteomic datasets with matched metagenomic and metatranscriptomic sequencing data acquired from complex microbial communities in a biological wastewater treatment plant. The results showed that many more peptides and proteins can be identified when assembly graphs were utilized, improving the characterization of the proteins expressed in the microbial communities. The additional proteins we identified contribute to the characterization of important pathways such as those involved in degradation of chemical hazards. Our tools are released as open-source software on github at https://github.com/COL-IU/Graph2Pro. PMID:27918579

  9. Systematic identification of high crash locations

    DOT National Transportation Integrated Search

    2001-05-01

    The objective of this project is to develop tools and procedures by which Iowa engineers can identify potentially hazardous roadway locations and designs, and to demonstrate the utility of these tools by developing candidate lists of high crash locat...

  10. Opportunity Stretches Out 3-D

    NASA Image and Video Library

    2004-02-02

    This is a three-dimensional stereo anaglyph of an image taken by the front hazard-identification camera onboard NASA Mars Exploration Rover Opportunity, showing the rover arm in its extended position. 3D glasses are necessary to view this image.

  11. 40 CFR 256.11 - Recommendations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... authorized State hazardous waste management program under subtitle C of the Act. (e) The State plan should... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Identification of Responsibilities...

  12. 40 CFR 256.11 - Recommendations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... authorized State hazardous waste management program under subtitle C of the Act. (e) The State plan should... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR DEVELOPMENT AND IMPLEMENTATION OF STATE SOLID WASTE MANAGEMENT PLANS Identification of Responsibilities...

  13. Modeling Philosophies and Applications

    EPA Pesticide Factsheets

    All models begin with a framework and a set of assumptions and limitations that go along with that framework. In terms of fracing and RA, there are several places where models and parameters must be chosen to complete hazard identification.

  14. About the Environmental Public Health Division (EPHD) of EPA's National Health and Environmental Effects Research Laboratory

    EPA Pesticide Factsheets

    The EPHD performs integrated epidemiological, clinical, animal and cellular biological research and statistical modeling to provide the scientific foundation in support of hazard identification, risk assessment, and standard setting.

  15. Limitations related to marine operations in the Barents Sea

    NASA Astrophysics Data System (ADS)

    Gudmestad, O. T.

    2017-12-01

    Some marine activities in the Barents Sea are normally ongoing year-round; others are dependent on limited weather windows. The limitations for the marine operations are the special weather conditions characterized by unpredictable Polar Low situations during the fall, winter and spring seasons, as well as cold temperatures that also are causing sea spray icing and the potential for drifting ice in certain parts of the Sea. It must also be realized that large distances combined with challenging meteorological and oceanographic criteria as well as darkness during the winter period represents a concern for evacuation and rescue, should it be necessary to abandon ships and platforms. The long distances to the locations farthest away from shore are, furthermore, out of reach of helicopter assistance. These aspects make it necessary to conduct hazard identification studies and to include all relevant historical knowledge in the hazard identification session, prior to the execution of marine operations in the Barents Sea.

  16. An interlaboratory comparison of nanosilver characterisation and hazard identification: Harmonising techniques for high quality data.

    PubMed

    Jemec, Anita; Kahru, Anne; Potthoff, Annegret; Drobne, Damjana; Heinlaan, Margit; Böhme, Steffi; Geppert, Mark; Novak, Sara; Schirmer, Kristin; Rekulapally, Rohit; Singh, Shashi; Aruoja, Villem; Sihtmäe, Mariliis; Juganson, Katre; Käkinen, Aleksandr; Kühnel, Dana

    2016-02-01

    Within the FP7 EU project NanoValid a consortium of six partners jointly investigated the hazard of silver nanoparticles (AgNPs) paying special attention to methodical aspects that are important for providing high-quality ecotoxicity data. Laboratories were supplied with the same original stock dispersion of AgNPs. All partners applied a harmonised procedure for storage and preparation of toxicity test suspensions. Altogether ten different toxicity assays with a range of environmentally relevant test species from different trophic levels were conducted in parallel to AgNP characterisation in the respective test media. The paper presents a comprehensive dataset of toxicity values and AgNP characteristics like hydrodynamic sizes of AgNP agglomerates and the share (%) of Ag(+)-species (the concentration of Ag(+)-species in relation to the total measured concentration of Ag). The studied AgNP preparation (20.4±6.8 nm primary size, mean total Ag concentration 41.14 mg/L, 46-68% of soluble Ag(+)-species in stock, 123.8±12.2 nm mean z-average value in dH2O) showed extreme toxicity to crustaceans Daphnia magna, algae Pseudokirchneriella subcapitata and zebrafish Danio rerio embryos (EC50<0.01 mg total Ag/L), was very toxic in the in vitro assay with rainbow trout Oncorhynchus mykiss gut cells (EC50: 0.01-1 mg total Ag/L); toxic to bacteria Vibrio fischeri, protozoa Tetrahymena thermophila (EC50: 1-10 mg total Ag/L) and harmful to marine crustaceans Artemia franciscana (EC50: 10-100 mg total Ag/L). Along with AgNPs, also the toxicity of AgNO3 was analyzed. The toxicity data revealed the same hazard ranking for AgNPs and AgNO3 (i.e. the EC50 values were in the same order of magnitude) proving the importance of soluble Ag(+)-species analysis for predicting the hazard of AgNPs. The study clearly points to the need for harmonised procedures for the characterisation of NMs. Harmonised procedures should consider: (i) measuring the AgNP properties like hydrodynamic size and metal ions species in each toxicity test medium at a range of concentrations, and (ii) including soluble metal salt control both in toxicity testing as well as in Ag(+)-species measurements. The present study is among the first nanomaterial interlaboratory comparison studies with the aim to improve the hazard identification testing protocols. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  17. Coastal Risk Assessment Framework tool for the identification of hotspots along the Emilia-Romagna coastline (northern Italy)

    NASA Astrophysics Data System (ADS)

    Armaroli, Clara; Duo, Enrico; Ciavola, Paolo

    2017-04-01

    The Emilia-Romagna coastline is located in northern Italy, facing the Adriatic sea. The area is especially exposed to the flooding hazard because of its low lying nature, high urbanisation and the large exploitation of beach resources for tourism. The identification of hotspots where marine flooding can cause significant damages is, therefore, a key issue. The methodology implemented to identify hotspots is based on the Coastal Risk Assessment Framework tool that was developed in the RISC-KIT project (www.risckit.eu). The tool combines the hazard component with different exposure indicators and is applied along predefined coastal sectors of almost 1 Km alongshore length. The coastline was divided into 106 sectors in which each component was analysed. The hazard part was evaluated through the computation of maximum water levels, obtained as the sum of wave set-up, storm surge and tide, calculated along representative beach profiles, one per sector, and for two return periods (10 and 100 years). The data for the computation of the maximum water level were extracted from the literature. The landward extension of flood-prone areas in each sector was the extension of the flood maps produced by the regional authorities for the EU Flood Directive and for the same return periods. The exposure indicators were evaluated taking into account the location and type of different assets in each sector and in flood-prone areas. Specifically, the assets that were taken into account are: the transport network, the utilities (water, gas and electricity) networks, the land use typologies, the social vulnerability status of the population and the business sector. Each component was then ranked from 1 to 5, considering a scale based on their computed value (hazard), importance and location (exposure indicators). A final coastal index (CI) was computed as the root mean square of the geometrical mean of the exposure indicators multiplied by the hazard indicator. Land use typologies were valued taking into account a classification produced by the regional authorities for the Flood Directive. The social vulnerability status of the population was derived from data produced by the National Statistic Institute. The regional managers provided the location of transport and utilities networks. The business indicator was built considering the tourist arrivals in each coastal municipality compared to the total number of arrivals. The results showed that the coast is very exposed to flooding and that the 100 year return period event leads to the identification of a large number of hotspots (65 over 106) defined as sectors with CI > 2.5. The main drivers for the hotspot identification were the hazard indicator and the land use typologies, because important transport/utilities network are not located in flood-prone areas. The most critical sectors are situated in the central-southern part of the coastline, where the most attractive tourist facilities are located and where the coastal corridor is occupied by a continuous urbanisation.

  18. The local lymph node assay and skin sensitization testing.

    PubMed

    Kimber, Ian; Dearman, Rebecca J

    2010-01-01

    The mouse local lymph node assay (LLNA) is a method for the identification and characterization of skin sensitization hazards. In this context the method can be used both to identify contact allergens, and also determine the relative skin sensitizing potency as a basis for derivation of effective risk assessments.The assay is based on measurement of proliferative responses by draining lymph node cells induced following topical exposure of mice to test chemicals. Such responses are known to be causally and quantitatively associated with the acquisition of skin sensitization and therefore provide a relevant marker for characterization of contact allergic potential.The LLNA has been the subject of exhaustive evaluation and validation exercises and has been assigned Organization for Economic Cooperation and Development (OECD) test guideline 429. Herein we describe the conduct and interpretation of the LLNA.

  19. Landscape Hazards in Yukon Communities: Geological Mapping for Climate Change Adaptation Planning

    NASA Astrophysics Data System (ADS)

    Kennedy, K.; Kinnear, L.

    2010-12-01

    Climate change is considered to be a significant challenge for northern communities where the effects of increased temperature and climate variability are beginning to affect infrastructure and livelihoods (Arctic Climate Impact Assessment, 2004). Planning for and adapting to ongoing and future changes in climate will require the identification and characterization of social, economic, cultural, political and biophysical vulnerabilities. This pilot project addresses physical landscape vulnerabilities in two communities in the Yukon Territory through community-scale landscape hazard mapping and focused investigations of community permafrost conditions. Landscape hazards are identified by combining pre-existing data from public utilities and private-sector consultants with new geophysical techniques (ground penetrating radar and electrical resistivity), shallow drilling, surficial geological mapping, and permafrost characterization. Existing landscape vulnerabilities are evaluated based on their potential for hazard (low, medium or high) under current climate conditions, as well as under future climate scenarios. Detailed hazard maps and landscape characterizations for both communities will contribute to overall adaptation plans and allow for informed development, planning and mitigation of potentially threatening hazards in and around the communities.

  20. Pre-deployment Alcohol Misuse Among Shipboard Active-Duty U.S. Military Personnel.

    PubMed

    Harbertson, Judith; Hale, Braden R; Watkins, Eren Y; Michael, Nelson L; Scott, Paul T

    2016-08-01

    The burden of alcohol misuse is unknown among shipboard U.S. Navy and Marine Corps military personnel immediately prior to deployment and may be elevated. Anonymous survey data on hazardous, dependent, and binge alcohol misuse and involuntary drug consumption were collected during 2012-2014 among shipboard personnel within approximately 2 weeks of deployment. Using the Alcohol Use Disorders Identification Test Consumption (AUDIT-C), hazardous alcohol misuse was defined using two cut-point scoring criteria: (1) ≥3 for women and ≥4 for men; and (2) ≥4 for women and ≥5 for men; binge drinking as ≥4 drinks for women and ≥5 drinks for men on a typical day in past 30 days; and dependent alcohol misuse as an AUDIT-C score of ≥8. Demographic- and sex-stratified self-reported alcohol misuse prevalence was reported for analysis conducted during 2014-2015. Among 2,351 male and female shipboard personnel, 39%-54% screened positive for hazardous, 27% for binge, and 15% for dependent alcohol use. Seven percent reported involuntary drug consumption history. A larger proportion of those aged 17-20 years screened positive for dependent alcohol use compared with the overall study population prevalence. A large proportion of shipboard personnel screened positive for hazardous and dependent alcohol use (18% among those aged <21 years) at deployment onset. These data can inform interventions targeting shipboard personnel engaging in hazardous use before progression to dependent use and enable early identification and care for dependent users. Future studies should include more comprehensive assessment of factors associated with involuntary drug consumption. Copyright © 2016 American Journal of Preventive Medicine. All rights reserved.

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