A Nested PCR Assay to Avoid False Positive Detection of the Microsporidian Enterocytozoon hepatopenaei (EHP) in Environmental Samples in Shrimp Farms

PubMed Central

Jaroenlak, Pattana; Sanguanrut, Piyachat; Williams, Bryony A. P.; Stentiford, Grant D.; Flegel, Timothy W.; Sritunyalucksana, Kallaya

2016-01-01

Hepatopancreatic microsporidiosis (HPM) caused by Enterocytozoon hepatopenaei (EHP) is an important disease of cultivated shrimp. Heavy infections may lead to retarded growth and unprofitable harvests. Existing PCR detection methods target the EHP small subunit ribosomal RNA (SSU rRNA) gene (SSU-PCR). However, we discovered that they can give false positive test results due to cross reactivity of the SSU-PCR primers with DNA from closely related microsporidia that infect other aquatic organisms. This is problematic for investigating and monitoring EHP infection pathways. To overcome this problem, a sensitive and specific nested PCR method was developed for detection of the spore wall protein (SWP) gene of EHP (SWP-PCR). The new SWP-PCR method did not produce false positive results from closely related microsporidia. The first PCR step of the SWP-PCR method was 100 times (104 plasmid copies per reaction vial) more sensitive than that of the existing SSU-PCR method (106 copies) but sensitivity was equal for both in the nested step (10 copies). Since the hepatopancreas of cultivated shrimp is not currently known to be infected with microsporidia other than EHP, the SSU-PCR methods are still valid for analyzing hepatopancreatic samples despite the lower sensitivity than the SWP-PCR method. However, due to its greater specificity and sensitivity, we recommend that the SWP-PCR method be used to screen for EHP in feces, feed and environmental samples for potential EHP carriers. PMID:27832178

A Nested PCR Assay to Avoid False Positive Detection of the Microsporidian Enterocytozoon hepatopenaei (EHP) in Environmental Samples in Shrimp Farms.

PubMed

Jaroenlak, Pattana; Sanguanrut, Piyachat; Williams, Bryony A P; Stentiford, Grant D; Flegel, Timothy W; Sritunyalucksana, Kallaya; Itsathitphaisarn, Ornchuma

2016-01-01

Hepatopancreatic microsporidiosis (HPM) caused by Enterocytozoon hepatopenaei (EHP) is an important disease of cultivated shrimp. Heavy infections may lead to retarded growth and unprofitable harvests. Existing PCR detection methods target the EHP small subunit ribosomal RNA (SSU rRNA) gene (SSU-PCR). However, we discovered that they can give false positive test results due to cross reactivity of the SSU-PCR primers with DNA from closely related microsporidia that infect other aquatic organisms. This is problematic for investigating and monitoring EHP infection pathways. To overcome this problem, a sensitive and specific nested PCR method was developed for detection of the spore wall protein (SWP) gene of EHP (SWP-PCR). The new SWP-PCR method did not produce false positive results from closely related microsporidia. The first PCR step of the SWP-PCR method was 100 times (104 plasmid copies per reaction vial) more sensitive than that of the existing SSU-PCR method (106 copies) but sensitivity was equal for both in the nested step (10 copies). Since the hepatopancreas of cultivated shrimp is not currently known to be infected with microsporidia other than EHP, the SSU-PCR methods are still valid for analyzing hepatopancreatic samples despite the lower sensitivity than the SWP-PCR method. However, due to its greater specificity and sensitivity, we recommend that the SWP-PCR method be used to screen for EHP in feces, feed and environmental samples for potential EHP carriers.

Design features to enhance external hip protector adherence in the nursing home setting.

PubMed

Honkanen, Lisa A; Dehner, Melissa L; Lachs, Mark S

2006-11-01

To determine the preferences for external hip protector (EHP) design features of both certified nursing assistants (CNAs) and nursing home laundry personnel, and to test the durability of favored model features. Cross-sectional descriptive study of CNAs' and laundry personnels' preferences and a prospective experimental study of EHP fastener durability under institutional laundry conditions. Three urban nursing homes and a hospital-based laundry service. Twenty-seven CNAs, 4 laundry service supervisors. Five focus groups with CNAs and a survey of laundry supervisors were conducted to elicit preferences of EHP design features with an emphasis on convenience and durability. A laundry test of 20 EHPs was conducted to compare these design features. There was wide agreement among CNAs and laundry personnel that EHPs with soft pads in garments of light neutral colors, and cotton-blend fabrics were most preferred. CNAs preferred sewn-in pads to removeable ones, but laundry personnel had no consensus on this issue. For dependent residents, wraparound (front opening) garments using Velcro were preferred by CNAs, whereas laundry supervisors preferred snap closures. When EHP underwent repeated washing in the laundry test, Velcro and snaps were functionally comparable at 52 cycles. Garments constructed of heavyweight cotton blends, polyester, or cotton with spandex maintained elasticity at 52 weeks, whereas the lightweight cotton blend stretched significantly. Based on CNAs' preferences, laundry personnels' input, and a laundry test, EHP design features that could enhance both caregiver efficiency and resident comfort include soft pads sewn into a light-colored (but non-white) heavier weight cotton-blend garment, with the availability of both a pull-up style and a wraparound style using Velcro fasteners. Snaps did not demonstrate superior durability in the laundry test, but further comparison with Velcro under clinical conditions is indicated. Education and inclusion of CNAs in EHP decision making are important ways to improve EHP adherence.

Atomic resolution structure of EhpR: phenazine resistance in Enterobacter agglomerans Eh1087 follows principles of bleomycin/mitomycin C resistance in other bacteria

PubMed Central

2011-01-01

Background The phenazines are redox-active secondary metabolites that a large number of bacterial strains produce and excrete into the environment. They possess antibiotic activity owing to the fact that they can reduce molecular oxygen to toxic reactive oxygen species. In order to take advantage of this activity, phenazine producers need to protect themselves against phenazine toxicity. Whereas it is believed that phenazine-producing pseudomonads possess highly active superoxide dismutases and catalases, it has recently been found that the plant-colonizing bacterium Enterobacter agglomerans expresses a small gene ehpR to render itself resistant towards D-alanyl-griseoluteic acid, the phenazine antibiotic produced by this strain. Results To understand the resistance mechanism installed by EhpR we have determined its crystal structure in the apo form at 2.15 Å resolution and in complex with griseoluteic acid at 1.01 Å, respectively. While EhpR shares a common fold with glyoxalase-I/bleomycin resistance proteins, the ligand binding site does not contain residues that some related proteins employ to chemically alter their substrates. Binding of the antibiotic is mediated by π-stacking interactions of the aromatic moiety with the side chains of aromatic amino acids and by a few polar interactions. The dissociation constant KD between EhpR and griseoluteic acid was quantified as 244 ± 45 μM by microscale thermophoresis measurements. Conclusions The data accumulated here suggest that EhpR confers resistance by binding D-alanyl-griseoluteic acid and acting as a chaperone involved in exporting the antibiotic rather than by altering it chemically. It is tempting to speculate that EhpR acts in concert with EhpJ, a transport protein of the major facilitator superfamily that is also encoded in the phenazine biosynthesis operon of E. agglomerans. The low affinity of EhpR for griseoluteic acid may be required for its physiological function. PMID:21849072

HLA-inferred extended haplotype disparity level is more relevant than the level of HLA mismatch alone for the patients survival and GvHD in T cell-replate hematopoietic stem cell transplantation from unrelated donor.

PubMed

Nowak, Jacek; Nestorowicz, Klaudia; Graczyk-Pol, Elzbieta; Mika-Witkowska, Renata; Rogatko-Koros, Marta; Jaskula, Emilia; Koscinska, Katarzyna; Madej, Sylwia; Tomaszewska, Agnieszka; Nasilowska-Adamska, Barbara; Szczepinski, Andrzej; Halaburda, Kazimierz; Dybko, Jaroslaw; Kuliczkowski, Kazimierz; Czerw, Tomasz; Giebel, Sebastian; Holowiecki, Jerzy; Baranska, Malgorzata; Pieczonka, Anna; Wachowiak, Jacek; Czyz, Anna; Gil, Lidia; Lojko-Dankowska, Anna; Komarnicki, Mieczyslaw; Bieniaszewska, Maria; Kucharska, Agnieszka; Hellmann, Andrzej; Gronkowska, Anna; Jedrzejczak, Wieslaw W; Markiewicz, Miroslaw; Koclega, Anna; Kyrcz-Krzemien, Slawomira; Mielcarek, Monika; Kalwak, Krzysztof; Styczynski, Jan; Wysocki, Mariusz; Drabko, Katarzyna; Wojcik, Beata; Kowalczyk, Jerzy; Gozdzik, Jolanta; Pawliczak, Daria; Gwozdowicz, Slawomir; Dziopa, Joanna; Szlendak, Urszula; Witkowska, Agnieszka; Zubala, Marta; Gawron, Agnieszka; Warzocha, Krzysztof; Lange, Andrzej

2018-06-01

Serious risks in unrelated hematopoietic stem cell transplantation (HSCT) including graft versus host disease (GvHD) and mortality are associated with HLA disparity between donor and recipient. The increased risks might be dependent on disparity in not-routinely-tested multiple polymorphisms in genetically dense MHC region, being organized in combinations of two extended MHC haplotypes (Ehp). We assessed the clinical role of donor-recipient Ehp disparity levels in N = 889 patients by the population-based detection of HLA allele phase mismatch. We found increased GvHD incidences and mortality rates with increasing Ehp mismatch level even with the same HLA mismatch level. In multivariate analysis HLA mismatch levels were excluded from models and Ehp disparity level remained independent prognostic factor for high grade acute GvHD (p = 0.000037, HR = 10.68, 95%CI 5.50-32.5) and extended chronic GvHD (p < 0.000001, HR = 15.51, CI95% 5.36-44.8). In group with single HLA mismatch, patients with double Ehp disparity had worse 5-year overall survival (45% vs. 56%, p = 0.00065, HR = 4.05, CI95% 1.69-9.71) and non-relapse mortality (40% vs. 31%, p = 0.00037, HR = 5.63, CI95% 2.04-15.5) than patients with single Ehp disparity. We conclude that Ehp-linked factors contribute to the high morbidity and mortality in recipients given HLA-mismatched unrelated transplant and Ehp matching should be considered in clinical HSCT. Copyright © 2018. Published by Elsevier Inc.

Dense populations of the microsporidian Enterocytozoon hepatopenaei (EHP) in feces of Penaeus vannamei exhibiting white feces syndrome and pathways of their transmission to healthy shrimp.

PubMed

Tang, Kathy F J; Han, Jee Eun; Aranguren, Luis Fernando; White-Noble, Brenda; Schmidt, Margeaux M; Piamsomboon, Patharapol; Risdiana, Eris; Hanggono, Bambang

2016-10-01

White feces syndrome (WFS) is an emerging problem for penaeid shrimp farming industries in SE Asia countries, Thailand, Malaysia, Vietnam, Indonesia, China, and in India. This occurrence of this syndrome is usually first evidenced by the appearance of white fecal strings floating on surface of the shrimp ponds. The gross signs of affected shrimp include the appearance of a whitish hindgut and loose carapace, and it is associated with reduced feeding and growth retardation. To investigate the nature of the white feces syndrome, samples of white feces and shrimp hepatopancreas tissue were collected from Penaeus vannamei in affected farms in Indonesia, and these were examined histologically. Within the white feces, we found densely packed spores of the microsporidian Enterocytozoon hepatopenaei (abbreviated as EHP) and relatively fewer numbers of rod-shaped bacteria. From WFS ponds, hepatopancreas samples form 30 individual shrimp were analyzed by histology and in situ hybridization. The results showed that all of the shrimp examined were infected with EHP accompanied by septic hepatopancreatic necrosis (SHPN). Midgut epithelial cells were also infected and this increased the number of tissue types being affected by EHP. By PCR, EHP was detected in all the samples analyzed from WFS-affected ponds, but not in those sampled from healthy shrimp ponds. To determine the modes of transmission for this parasite, we performed feeding and cohabitation bioassays, the results showed that EHP can be transmitted through per os feeding of EHP-infected hepatopancreas tissue to healthy shrimp and through cohabitation ofinfected and healthy shrimp. In addition, we found the use of Fumagillin-B, an antimicrobial agent, was ineffective in either reducing or eliminating EHP in infected shrimp. Copyright © 2016 Elsevier Inc. All rights reserved.

Mixed lineage kinase domain-like protein induces RGC-5 necroptosis following elevated hydrostatic pressure.

PubMed

Liao, Lvshuang; Shang, Lei; Li, Na; Wang, Shuchao; Wang, Mi; Huang, Yanxia; Chen, Dan; Huang, Jufang; Xiong, Kun

2017-10-01

Receptor-interacting protein 3 (RIP3) is an essential component of the necroptosis signaling pathway. Phosphorylation of its downstream target, mixed lineage kinase domain-like protein (MLKL), has been proposed to induce necroptosis by initiating Ca2+ influx. Our previous studies have shown that RGC-5 retinal ganglion cells undergo RIP3-mediated necroptosis following elevated hydrostatic pressure (EHP). However, the molecular mechanism underlying necroptosis induction downstream of RIP3 is still not well understood. Here, we investigated the effects of MLKL during EHP-induced necroptosis, and primarily explored the relationship between MLKL and Ca2+ influx. Immunofluorescence staining showed that the expression of MLKL was increased 12 h after EHP. Western blot analysis demonstrated that the phosphorylated and unphosphorylated forms of both RIP3 and MLKL were up-regulated 12 h after EHP, while inhibition of RIP3 by GSK'872 decreased the expression of phosphorylated MLKL at the same stage. Propidium iodide staining, lactate dehydrogenase release assays, flow cytometry, and electron microscopy revealed the increased necrosis of RGC-5 cells 12 h after EHP, which coincided with elevated cytosolic Ca2+ concentrations. Depletion of extracellular Ca2+ and siRNA-mediated silencing of MLKL significantly reduced EHP-induced necrosis. Both MLKL-specific siRNA and GSK'872 treatment diminished Ca2+ influx. Thus, our findings suggest that MLKL may be the key mediator of necroptosis downstream of RIP3 phosphorylation and may be involved in increasing intracellular Ca2+ concentrations in EHP-induced RGC-5 necroptosis. © The Author 2017. Published by Oxford University Press on behalf of the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Elevated heat pump effects of dust aerosol over Northwestern China during summer

NASA Astrophysics Data System (ADS)

Tang, Yaoguo; Han, Yongxiang; Ma, Xiaoyan; Liu, Zhaohuan

2018-05-01

The Elevated Heat Pump (EHP) effect demonstrates a significant interaction between the aerosol climatic effect and the monsoon, both are important for climate research. In Northwestern China, the influence of EHP mechanism is still lacking in research. In this study, the EHP effects in Northwestern China are investigated by three sensitivity tests using a WRF-Chem model coupled with the Shao dust emission scheme. Results show that: 1) the anomalous circulation caused by dust aerosols are proved to the existence of EHP effect in Northwestern China; 2) three updrafts over the desert are transported eastward at high altitude and subside in Northeastern China, forming a complete secondary circulation with low-level easterly flow from Badain Jaran and Tengger to Taklimakan; 3) a northeasternerly anomaly flow from Northeastern China can affect the intensity of East Asian summer monsoon (EASM), and increase precipitation in the middle and lower reaches of the Yangtze River and decrease precipitation in Northeastern China. 4) We present a conceptual model of EHP in Northwestern China to provide a better understanding of the climatic effects of dust aerosols.

Comments on "The "Elevated Heat Pump" Hypothesis for the Aerosol-Monsoon Hydroclimate Link: "Grounded" in Observations?" by S. Nigam and M. Bollasina

NASA Technical Reports Server (NTRS)

Lau, K. M.; Kim, K. M.

2010-01-01

In their recent paper Nigam and Bollasina [2010, hereafter NB] claimed to have found observational evidences that are at variance with the Elevated Heat Pump (EHP) hypothesis regarding the possible impacts of absorbing aerosols on the South Asian summer monsoon [Lau et al., 2006; Lau and Km 2006). We found NB's arguments and inferences against the EHP hypothesis flawed, stemming from a lack of understanding and an out-of-context interpretation of the hypothesis. It was argued that the simultaneous negative correlation of aerosol with rainfall, and correlations with other quantities in May as evidences against the EHP hypothesis. They cannot be more wrong in that argument. First, Lau and Kim [2006, hereafter, LKO6] never stated that the main rainfall response to EHP is in May. Second, the EHP is about responses of the entire Indian monsoon system that are non-local in space and time with respect to the aerosol forcing. Third, the correlation maps shown in NB, including the increased convection over the Bay of Bengal is not the response to EHP but rather represents the large-scale circulation that provides the build-up of the aerosols, before the onset of the monsoon rainfall over India. Because aerosol can only accumulate where there is little or no wash-out by rain, the negative correlation is a necessary condition for increased atmospheric loading of aerosols.

The effects and regulatory mechanism of RIP3 on RGC-5 necroptosis following elevated hydrostatic pressure.

PubMed

Shang, Lei; Ding, Wei; Li, Na; Liao, Lvshuang; Chen, Dan; Huang, Jufang; Xiong, Kun

2017-02-06

Necroptosis is a type of regulated cell death that has been implicated in various diseases. Receptor-interacting protein 3 (RIP3), a member of the RIP family, is an important mediator of the necroptotic pathway. Cleavage of RIP3 at Asp328 by caspase-8 abolishes the kinase activity of RIP3, which is critical for necroptosis. Moreover, RIP3 is significantly upregulated during the early stages of acute high intra-ocular pressure and oxygen glucose deprivation. In this study, the effects of RIP3 during elevated hydrostatic pressure (EHP) were investigated and the possible mechanism through which caspase-8 regulated RIP3 cleavage was explored. Flow cytometry analysis revealed that the number of EHP-induced necrotic retinal ganglion cell 5 (RGC-5) cells was reduced after RIP3-knockdown. Furthermore, malondialdehyde (MDA) levels and glycogen phosphorylase (PYGL) activity in normal RGC-5 cells were much higher than those in RIP3-knockdown cells after EHP. EHP-induced RGC-5 necrosis was significantly reduced after treatment with butylated hydroxyanisole (BHA), a reactive oxygen species (ROS) scavenger. MDA levels and PYGL activity were lower in normal RGC-5 cells than those in cells with caspase-8 inhibition after EHP. Western blot analysis demonstrated that the RIP3 cleavage product was upregulated in cells with caspase-8 inhibition. Additionally, flow cytometry analysis revealed that the number of EHP-induced necrotic RGC-5 cells was increased after caspase-8 inhibition. Our results suggested that RGC-5 necroptosis following EHP was mediated by RIP3 through induction of PYGL activity and subsequent ROS accumulation. Thus, caspase-8 may participate in the regulation of RGC-5 necroptosis via RIP3 cleavage. © The Author 2016. Published by Oxford University Press on behalf of the Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Combining CMPO and HEH[EHP] for Separating Trivalent Lanthanides from the Transuranic Elements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Braley, Jenifer C.; Lumetta, Gregg J.; Carter, Jennifer C.

2013-09-05

Combining octyl(phenyl)-N,N-diisobutyl-carbamoylmethylphosphine oxide (CMPO) and 2-ethylhexylphosphonic acid mono-2-ethylhexyl ester (HEH[EHP]) into a single process solvent for separating transuranic elements from liquid high-level waste is explored. The lanthanides and americium can be co-extracted from HNO3 into 0.2 mol/L CMPO + 1.0 mol/L HEH[EHP] in n-dodecane. The extraction is relatively insensitive to the HNO3 concentration within 0.1 to 5 mol/L HNO3. Americium can be selectively stripped from the CMPO/HEH[EHP] solvent into a citrate-buffered N-(2-hydroxyethyl)ethylenediaminetriacetic acid solution . Separation factors >14 can be achieved in the range pH 2.5 to 3.7, and the separation factors are relatively insensitive to pH, a major advantagemore » of this solvent formulation.« less

Measuring health-related quality of life in women with endometriosis: comparing the clinimetric properties of the Endometriosis Health Profile-5 (EHP-5) and the EuroQol-5D (EQ-5D).

PubMed

Aubry, G; Panel, P; Thiollier, G; Huchon, C; Fauconnier, A

2017-06-01

Which of the Endometriosis Health Profile-5 (EHP-5) and the EuroQol-5D (EQ-5D) is the most efficient to assess quality of life in women suffering from endometriosis? Although EHP-5 and EQ-5D instruments had an excellent responsiveness, EHP-5 has a better discriminative ability than EQ-5 to measure health-related quality of life (HrQoL). Proper measurement of HrQoL is important in endometriosis. While many quality of life instruments are available, few have been completely validated in endometriosis. The EHP-5 and the EQ-5D are short and practical scales, which may be useful. Literature is lacking to determine which one is the most suitable in clinical practice or in clinical research. This prospective and observational study conducted between 1 January 2012 and 31 December 2013 included a total of 253 consecutive women with proven endometriosis, undergoing medical or surgical treatment, in 2 French tertiary care centers. Women over 18 years consulting for painful symptoms of at least 3 months' duration or for infertility, with endometriosis proven histologically or radiologically, were requested to fill in the 2 scales before (T0) and 12 months after treatment (T1). Construct validity consisted in testing presupposed relationships between the scales and the characteristics of the patients or the endometriosis. Responsiveness to change was calculated for all patients and in each treatment group. Effect sizes were used according to Cohen's d method. A total of 216 women filled in completely all the questionnaires at T0 and 133 (61.6%) at T1. EHP-5 and EQ-5D had good discriminative abilities regarding the patients' symptoms, with significant superiority of EHP-5 concerning three of the nine hypotheses. The largest difference was that calculated for the 'intensity of dysmenorrhea' using the Visual Analogic Scale, with respectively effect size from Cohen's d (ES) = 0.86 95% CI (0.54-1.17) for EHP-5 versus 0.48 95% CI (0.16-0.79) for EQ-5D. There were no differences in EHP-5 or in EQ-5D scores between subgroups according to the characteristics of endometriosis. Overall responsiveness was excellent and equivalent for EHP-5 and for EQ-5D, with, respectively, ES = 0.81 95% CI (0.56-1.56) versus ES = 0.95 95% CI (0.68-1.20). In subgroup analyses, EHP-5 was responsive in case of medical treatment with ES = 0.93 95% CI (0.07-1.70), whereas EQ-5D was not, ES = 0.73 95% CI (-0.06-1.47). Our study population included patients with symptomatic and mainly severe forms of endometriosis, which may suggest a spectrum bias. The evaluation of responsiveness in case of medical treatment was based on a small number of patients, which limits the interpretation of the difference found between the two scales in this subgroup. EHP-5 is a simple, efficient and valid tool for evaluating quality of life in daily practice and also valuable to provide a primary outcome in clinical studies evaluating treatment efficacy. This work was funded by the Direction à la Recherche Clinique et à l'Innovation of Versailles, France. The authors have no conflicts of interest. None. © The Author 2017. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

An Integrated Chemical Environment to Support 21st-Century Toxicology.

PubMed

Bell, Shannon M; Phillips, Jason; Sedykh, Alexander; Tandon, Arpit; Sprankle, Catherine; Morefield, Stephen Q; Shapiro, Andy; Allen, David; Shah, Ruchir; Maull, Elizabeth A; Casey, Warren M; Kleinstreuer, Nicole C

2017-05-25

SUMMARY : Access to high-quality reference data is essential for the development, validation, and implementation of in vitro and in silico approaches that reduce and replace the use of animals in toxicity testing. Currently, these data must often be pooled from a variety of disparate sources to efficiently link a set of assay responses and model predictions to an outcome or hazard classification. To provide a central access point for these purposes, the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods developed the Integrated Chemical Environment (ICE) web resource. The ICE data integrator allows users to retrieve and combine data sets and to develop hypotheses through data exploration. Open-source computational workflows and models will be available for download and application to local data. ICE currently includes curated in vivo test data, reference chemical information, in vitro assay data (including Tox21 TM /ToxCast™ high-throughput screening data), and in silico model predictions. Users can query these data collections focusing on end points of interest such as acute systemic toxicity, endocrine disruption, skin sensitization, and many others. ICE is publicly accessible at https://ice.ntp.niehs.nih.gov. https://doi.org/10.1289/EHP1759.

An Integrated Chemical Environment to Support 21st-Century Toxicology

PubMed Central

Bell, Shannon M.; Phillips, Jason; Sedykh, Alexander; Tandon, Arpit; Sprankle, Catherine; Morefield, Stephen Q.; Shapiro, Andy; Allen, David; Shah, Ruchir; Maull, Elizabeth A.; Casey, Warren M.

2017-01-01

Summary: Access to high-quality reference data is essential for the development, validation, and implementation of in vitro and in silico approaches that reduce and replace the use of animals in toxicity testing. Currently, these data must often be pooled from a variety of disparate sources to efficiently link a set of assay responses and model predictions to an outcome or hazard classification. To provide a central access point for these purposes, the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods developed the Integrated Chemical Environment (ICE) web resource. The ICE data integrator allows users to retrieve and combine data sets and to develop hypotheses through data exploration. Open-source computational workflows and models will be available for download and application to local data. ICE currently includes curated in vivo test data, reference chemical information, in vitro assay data (including Tox21TM/ToxCast™ high-throughput screening data), and in silico model predictions. Users can query these data collections focusing on end points of interest such as acute systemic toxicity, endocrine disruption, skin sensitization, and many others. ICE is publicly accessible at https://ice.ntp.niehs.nih.gov. https://doi.org/10.1289/EHP1759 PMID:28557712

The Florence Statement on Triclosan and Triclocarban

PubMed Central

Halden, Rolf U.; Aiello, Allison E.; Andrews, David; Arnold, William A.; Fair, Patricia; Fuoco, Rebecca E.; Geer, Laura A.; Johnson, Paula I.; Lohmann, Rainer; McNeill, Kristopher; Sacks, Victoria P.; Schettler, Ted; Weber, Roland; Zoeller, R. Thomas; Blum, Arlene

2017-01-01

Summary: The Florence Statement on Triclosan and Triclocarban documents a consensus of more than 200 scientists and medical professionals on the hazards of and lack of demonstrated benefit from common uses of triclosan and triclocarban. These chemicals may be used in thousands of personal care and consumer products as well as in building materials. Based on extensive peer-reviewed research, this statement concludes that triclosan and triclocarban are environmentally persistent endocrine disruptors that bioaccumulate in and are toxic to aquatic and other organisms. Evidence of other hazards to humans and ecosystems from triclosan and triclocarban is presented along with recommendations intended to prevent future harm from triclosan, triclocarban, and antimicrobial substances with similar properties and effects. Because antimicrobials can have unintended adverse health and environmental impacts, they should only be used when they provide an evidence-based health benefit. Greater transparency is needed in product formulations, and before an antimicrobial is incorporated into a product, the long-term health and ecological impacts should be evaluated. https://doi.org/10.1289/EHP1788 PMID:28632490

Stock-outs of essential health products in Mozambique - longitudinal analyses from 2011 to 2013.

PubMed

Wagenaar, Bradley H; Gimbel, Sarah; Hoek, Roxanne; Pfeiffer, James; Michel, Cathy; Manuel, João Luis; Cuembelo, Fatima; Quembo, Titos; Afonso, Pires; Gloyd, Stephen; Sherr, Kenneth

2014-07-01

To assess the relationship between health system factors and facility-level EHP stock-outs in Mozambique. Service provisions were assessed in 26 health facilities and 13 district warehouses in Sofala Province, Mozambique, from July to August in 2011-2013. Generalised estimating equations were used to model factors associated with facility-level availability of essential drugs, supplies and equipment. Stock-out rates for drugs ranged from 1.3% for oral rehydration solution to 20.5% for Depo-Provera and condoms, with a mean stock-out rate of 9.1%; mean stock-out rates were 15.4% for supplies and 4.1% for equipment. Stock-outs at the district level accounted for 27.1% (29/107) of facility-level drug stock-outs and 44.0% (37/84) of supply stock-outs. Each 10-km increase in the distance from district distribution warehouses was associated with a 31% (CI: 22-42%), 28% (CI: 17-40%) or 27% (CI: 7-50%) increase in rates of drug, supply or equipment stock-outs, respectively. The number of heath facility staff was consistently negatively associated with the occurrence of stock-outs. Facility-level stock-outs of EHPs in Mozambique are common and appear to disproportionately affect those living far from district capitals and near facilities with few health staff. The majority of facility-level EHP stock-outs in Mozambique occur when stock exists at the district distribution centre. Innovative methods are urgently needed to improve EHP supply chains, requesting and ordering of drugs, facility and district communication, and forecasting of future EHP needs in Mozambique. Increased investments in public-sector human resources for health could potentially decrease the occurrence of EHP stock-outs. © 2014 John Wiley & Sons Ltd.

Stock-outs of essential health products in Mozambique-longitudinal analyses from 2011 to 2013

PubMed Central

Wagenaar, Bradley H.; Gimbel, Sarah; Hoek, Roxanne; Pfeiffer, James; Michel, Cathy; Manuel, João Luis; Cuembelo, Fatima; Quembo, Titos; Afonso, Pires; Gloyd, Stephen; Sherr, Kenneth

2015-01-01

objectives To assess the relationship between health system factors and facility-level EHP stock-outs in Mozambique. methods Service provisions were assessed in 26 health facilities and 13 district warehouses in Sofala Province, Mozambique, from July to August in 2011–2013. Generalised estimating equations were used to model factors associated with facility-level availability of essential drugs, supplies and equipment. results Stock-out rates for drugs ranged from 1.3% for oral rehydration solution to 20.5% for Depo-Provera and condoms, with a mean stock-out rate of 9.1%; mean stock-out rates were 15.4% for supplies and 4.1% for equipment. Stock-outs at the district level accounted for 27.1% (29/107) of facility-level drug stock-outs and 44.0% (37/84) of supply stock-outs. Each 10-km increase in the distance from district distribution warehouses was associated with a 31% (CI: 22–42%), 28% (CI: 17–40%) or 27% (CI: 7–50%) increase in rates of drug, supply or equipment stock-outs, respectively. The number of heath facility staff was consistently negatively associated with the occurrence of stock-outs. conclusions Facility-level stock-outs of EHPs in Mozambique are common and appear to disproportionately affect those living far from district capitals and near facilities with few health staff. The majority of facility-level EHP stock-outs in Mozambique occur when stock exists at the district distribution centre. Innovative methods are urgently needed to improve EHP supply chains, requesting and ordering of drugs, facility and district communication, and forecasting of future EHP needs in Mozambique. Increased investments in public-sector human resources for health could potentially decrease the occurrence of EHP stock-outs. PMID:24724617

Effect of HEH[EHP] impurities on the ALSEP solvent extraction process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holfeltz, Vanessa E.; Campbell, Emily L.; Peterman, Dean R.

In solvent extraction processes, organic phase impurities can negatively impact separation factors, hydrolytic performance, and overall system robustness. This affects the process-level viability of a separation concept and necessitates knowledge of the behavior and mechanisms to control impurities in the solvent. The most widespread way through which impurities are introduced into a system is through impure extractants and/or diluents used to prepare the solvent, and often development of new purification schemes to achieve the desired level of purity is needed. In this work, the acidic extractant, 2-ethylhexylphosphonic acid mono-2-ethylhexyl ester (HEH[EHP])—proposed for application in extractive processes aimed at separating trivalentmore » minor actinides from lanthanides and other fission products—is characterized with respect to its common impurities and their impact on Am(III) stripping in the Actinide Lanthanide SEParation (ALSEP) system. To control impurities in HEH[EHP], existing purification technologies commonly applied for the acidic organophosphorus reagents are reviewed, and a new method specific to HEH[EHP] purification is presented.« less

Environmental, health, and safety issues of sodium-sulfur batteries for electric and hybrid vehicles. Volume 1, Cell and battery safety

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ohi, J M

1992-09-01

This report is the first of four volumes that identify and assess the environmental, health, and safety issues involved in using sodium-sulfur (Na/S) battery technology as the energy source in electric and hybrid vehicles that may affect the commercialization of Na/S batteries. This and the other reports on recycling, shipping, and vehicle safety are intended to help the Electric and Hybrid Propulsion Division of the Office of Transportation Technologies in the US Department of Energy (DOE/EHP) determine the direction of its research, development, and demonstration (RD&D) program for Na/S battery technology. The reports review the status of Na/S battery RD&Dmore » and identify potential hazards and risks that may require additional research or that may affect the design and use of Na/S batteries. This volume covers cell design and engineering as the basis of safety for Na/S batteries and describes and assesses the potential chemical, electrical, and thermal hazards and risks of Na/S cells and batteries as well as the RD&D performed, under way, or to address these hazards and risks. The report is based on a review of the literature and on discussions with experts at DOE, national laboratories and agencies, universities, and private industry. Subsequent volumes will address environmental, health, and safety issues involved in shipping cells and batteries, using batteries to propel electric vehicles, and recycling and disposing of spent batteries. The remainder of this volume is divided into two major sections on safety at the cell and battery levels. The section on Na/S cells describes major component and potential failure modes, design, life testing and failure testing, thermal cycling, and the safety status of Na/S cells. The section on batteries describes battery design, testing, and safety status. Additional EH&S information on Na/S batteries is provided in the appendices.« less

ELECTRIC AND MAGNETIC FIELDS <100 KHZ IN ELECTRIC AND GASOLINE-POWERED VEHICLES.

PubMed

Tell, Richard A; Kavet, Robert

2016-12-01

Measurements were conducted to investigate electric and magnetic fields (EMFs) from 120 Hz to 10 kHz and 1.2 to 100 kHz in 9 electric or hybrid vehicles and 4 gasoline vehicles, all while being driven. The range of fields in the electric vehicles enclosed the range observed in the gasoline vehicles. Mean magnetic fields ranged from nominally 0.6 to 3.5 µT for electric/hybrids depending on the measurement band compared with nominally 0.4 to 0.6 µT for gasoline vehicles. Mean values of electric fields ranged from nominally 2 to 3 V m -1 for electric/hybrid vehicles depending on the band, compared with 0.9 to 3 V m -1 for gasoline vehicles. In all cases, the fields were well within published exposure limits for the general population. The measurements were performed with Narda model EHP-50C/EHP-50D EMF analysers that revealed the presence of spurious signals in the EHP-50C unit, which were resolved with the EHP-50D model. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Modeling of Optoelectronic Devices

NASA Technical Reports Server (NTRS)

Li, Jian-Zhong; Woo, Alex C. (Technical Monitor)

2000-01-01

Ultrafast modulation of semiconductor quantum well (QW) laser is of technological importance for information technology. Improvement by order(s) of magnitude in data transfer rate is possible as terahertz (THz) radiation is available for heating the laser at picosecond time scale. Optical gain modulation in the QW is achieved via temperature modulation of electron-hole plasma (EHP). Applications include free-space THz communication, optical switching, and pulse generation. The EHP in the semiconductor QW is described with a two-band model. Semiconductor Bloch equations with many-body effects are used to derive a hydrodynamical model for the active QW region. Because of ultrafast carrier-carrier scatterings in the order of 50 fs, EHP follows quasiequilibrium Fermi-Dirac distributions and THz field interacts incoherently with it. Carrier-longitudinal optical (LO) phonon scatterings and coherent laser-EHP interaction are treated microscopically in our physical model. A set of hydrodynamical equations for plasma density, temperature, and laser envelop amplitude are derived and Runge-Kutta method is adopted for numerical simulation. A typical 8 nm GaAs/Al(0.3)Ga(0.7) As single QW at 300 K is used. Additional information is contained in the original extended abstract.

Physiological response of broiler embryos to different incubator temperature profiles and maternal flock age during incubation. 1. Embryonic metabolism and day-old chick quality.

PubMed

Hamidu, J A; Torres, C A; Johnson-Dahl, M L; Korver, D R

2018-05-18

Broiler strain, maternal age, and incubation temperature influence embryo metabolism. Hatching eggs were obtained from young (Y; 28 to 34 wk, $\\bar{\\rm x}$ = 31.2 wk), mid (M; 36 to 45 wk, $\\bar{\\rm x}$ = 40.5 wk) and old (O; 49 to 54 wk, $\\bar{\\rm x}$ = 51.4 wk) Ross 708 (n = 88; Experiment 1) and Ross 308 [(n = 45; Experiment 2: (Y; 25 to 34 wk, $\\bar{\\rm x}$ = 30.5 wk), (M; 35 to 44 wk, $\\bar{\\rm x}$ = 40.2 wk), and (O; 49 to 54 wk, $\\bar{\\rm x}$ = 51.6 wk)] breeders. Eggs were stored for 2 to 4 d (18°C, 73% RH), and incubated for 14 d at 37.5°C and 56% RH. At 15 d (E15), 8 fertile eggs per flock age were incubated in individual metabolic chambers at 36.0, 36.5, 37.0, or 37.5°C until E21.5. Each temperature was repeated one additional time. O2 consumption and CO2 production were used to calculate embryonic heat production (EHP). Embryo temperature was measured as eggshell temperature (EST). Initial egg weight was used as a covariate; significance was assessed at P < 0.05. In Ross 708, daily EHP tended to be higher in M and O than Y treatments at E16; EHP of M was higher than Y and O eggs at E18; M and O were higher than O eggs at E19. Incubation at 37.0°C resulted in the highest EHP from E15 to E21, except at E17. Embryos at 37.5°C had reduced EHP beyond E17. Daily EST from E15 to E21 was higher at 37.5 and 37.0°C than at 36.0 and 36.5°C. In Ross 308, daily EST was highest at 37.5°C except at E20. Incubation temperature and EST were highly correlated (R2 = 0.90 to 0.89; P < 0.001). Ross 708 chicks were longer and hatched earlier at 37.0°C than at 36.0 and 37.5°C. EST and EHP increased with incubation temperature in Ross 708. In Ross 308, maternal flock age and incubation temperature did not impact EHP. However, EST was highest at 37.5°C except at E20. Ross 708 was more sensitive to incubation temperature than Ross 308.

Comment on "'Elevated Heat Pump' Hypothesis for the Aerosol-Monsoon Hydroclimate Link: 'Grounded' in Observations?" by S. Nigam and M. Bollasina

NASA Technical Reports Server (NTRS)

Lau, K. M.; Kim, K. M.

2011-01-01

In their recent paper, Nigam and Bollasina [2010] (hereinafter NB) claimed to have found observational evidences that are at variance with the elevated heat pump (EHP) hypothesis regarding the possible impacts of absorbing aerosols on the South Asian summer monsoon [Lau et al., 2006; Lau and Kim, 2006]. We found NB's arguments and inferences against the EHP hypothesis flawed, stemming from their own out of context interpretation of the hypothesis. NB argued that the simultaneous negative correlation of aerosol with rainfall, and correlations with other quantities in May, are evidence against the EHP hypothesis. Their argument cannot be justified. First, Lau and Kim [2006] (hereinafter LK06) never stated that the main rainfall response to EHP is in May. Second, the EHP is about responses of the entire Indian monsoon system that are nonlocal in space and time with respect to the aerosol forcing. As shown in Figure 4 of LK06, while the aerosol anomalies are strongest in April-May, the strongest rainfall response is in June-July, with the enhanced rainfall fed by an induced thermally driven circulation which brings additional moisture from the ocean to the Indian subcontinent. Third, the increased rainfall over the Bay of Bengal as shown in Figure 1a of NB and the increased low-level convergence in Figure 1f of NB do not necessarily reflect responses associated with EHP but rather the large ]scale circulation that provides the buildup of the aerosols before the onset of the monsoon rainfall over India. Because aerosol can only accumulate where there is little or no washout by rain, the negative correlation is a necessary condition for increased atmospheric loading of aerosols. For the same reason, the spatial distributions of rainfall and aerosol generally are offset with each other, i.e., high aerosol in regions of low rainfall. This is evident in Figure 1, which shows the climatological mean of the MODIS aerosol optical depth (AOD), and TRMM rainfall over India in May. The maximum AOD is found over the Indo-Gangetic Plain and the desert regions of northwest India and Pakistan

Process evaluation of an environmental health risk audit and action plan intervention to reduce alcohol related violence in licensed premises.

PubMed

Williams, Annie; Moore, Simon C; Shovelton, Claire; Moore, Laurence; Murphy, Simon

2016-05-28

Alcohol-related violence is associated with licensed premise environments and their management. There is a lack of evidence for effective interventions to address these, and there are significant barriers to implementation. This study aims to understand how development and implementation processes can facilitate intervention reach, fidelity and receipt and therefore provides key process data necessary to interpret the results of the randomised controlled trial conducted in parallel. A process evaluation, embedded within a randomised controlled trial. Intervention development and implementation were assessed via focus groups (n = 2) and semi-structured interviews (n = 22) with Environmental Health Practitioners (EHPs). Reach and fidelity were assessed via routinely collected intervention data, which was was collected from 276 licenced premises across Wales, UK. Case study semi-structured interviews with licensed premises proprietors (n = 30) explored intervention receipt. Intervention co-production with senior EHPs facilitated organisational adoption and implementation. Training events for EHPs played an important role in addressing wider organisational concerns regarding partnership working and the contextual integration of the intervention. EHPs delivered the intervention to 98 % of intervention premises; 35 % of premises should have received a follow up enforcement visit, however EHP confidence in dealing with alcohol risk factors meant only 7 % of premises received one. Premises therefore received a similar intervention dose regardless of baseline risk. Intervention receipt appeared to be greatest in premises with an existing commitment to prevention and those in urban environments. The study suggests that a collaborative approach to the development and diffusion of interventions is associated with high levels of organisational adoption, implementation and reach. However, the lack of enforcement visits represents implementation failure for a key mechanism of action that is likely to influence intervention effectiveness. To be effective, any future intervention may require a longer implementation period to develop EHP confidence in using enforcement approaches in this area and multiagency enforcement support, which includes the police, to deliver an adequate intervention dose.

Human Health Effects of Biphenyl: Key Findings and Scientific Issues.

PubMed

Li, Zheng; Hogan, Karen A; Cai, Christine; Rieth, Susan

2016-06-01

In support of the Integrated Risk Information System (IRIS), the U.S. Environmental Protection Agency (EPA) has evaluated the human health hazards of biphenyl exposure. We review key findings and scientific issues regarding expected human health effects of biphenyl. Scientific literature from 1926 through September 2012 was critically evaluated to identify potential human health hazards associated with biphenyl exposure. Key issues related to the carcinogenicity and noncancer health hazards of biphenyl were examined based on evidence from experimental animal bioassays and mechanistic studies. Systematic consideration of experimental animal studies of oral biphenyl exposure took into account the variety of study designs (e.g., study sizes, exposure levels, and exposure durations) to reconcile differing reported results. The available mechanistic and toxicokinetic evidence supports the hypothesis that male rat urinary bladder tumors arise through urinary bladder calculi formation but is insufficient to hypothesize a mode of action for liver tumors in female mice. Biphenyl and its metabolites may induce genetic damage, but a role for genotoxicity in biphenyl-induced carcinogenicity has not been established. The available health effects data for biphenyl provides suggestive evidence for carcinogenicity in humans, based on increased incidences of male rat urinary bladder tumors at high exposure levels and on female mouse liver tumors. Kidney toxicity is also a potential human health hazard of biphenyl exposure. Li Z, Hogan KA, Cai C, Rieth S. 2016. Human health effects of biphenyl: key findings and scientific issues. Environ Health Perspect 124:703-712; http://dx.doi.org/10.1289/ehp.1509730.

2012 NEHA/UL sabbatical report: vulnerability to potential impacts of climate change: adaptation and risk communication strategies for environmental health practitioners in the United Kingdom.

PubMed

Ratnapradipa, Dhitinut

2014-04-01

Climate change risk assessment, adaptation, and mitigation planning have become increasingly important to environmental health practitioners (EHPs). The NEHA/UL Sabbatical Exchange Award allowed me to investigate how EHPs in the UK are incorporating climate change planning and communication strategies into their work. Projected climate change risks in the UK include flooding, extreme heat, water shortages, severe weather, decreased air quality, and changes in vectors. Despite public perception and funding challenges, all the local government representatives with whom I met incorporated climate change risk assessment, adaptation, and mitigation planning into their work. The mandated Community Risk Register serves as a key planning document developed by each local government authority and is a meaningful way to look at potential climate change health risks. Adaptation and sustainability were common threads in my meetings. These often took the form of "going green" with transportation, energy efficiency, conserving resources, and building design because the efforts made sense monetarily as future cost savings. Communication strategies targeted a variety of audiences (EHPs, non-EHP government employees, politicians, and the general public) using a broad range of communication channels (professional training, lobbying, conferences and fairs, publications, print materials, Internet resources, social media, billboards, etc).

Electron-hole pairs generation rate estimation irradiated by isotope Nickel-63 in silicone using GEANT4

NASA Astrophysics Data System (ADS)

Kovalev, I. V.; Sidorov, V. G.; Zelenkov, P. V.; Khoroshko, A. Y.; Lelekov, A. T.

2015-10-01

To optimize parameters of beta-electrical converter of isotope Nickel-63 radiation, model of the distribution of EHP generation rate in semiconductor must be derived. By using Monte-Carlo methods in GEANT4 system with ultra-low energy electron physics models this distribution in silicon calculated and approximated with Gauss function. Maximal efficient isotope layer thickness and maximal energy efficiency of EHP generation were estimated.

All-Optical Switching and Unidirectional Plasmon Launching with Nonlinear Dielectric Nanoantennas

NASA Astrophysics Data System (ADS)

Krasnok, Alex; Li, Sergey; Lepeshov, Sergey; Savelev, Roman; Baranov, Denis G.; Alú, Andrea

2018-01-01

High-index dielectric nanoparticles have become a powerful platform for nonlinear nanophotonics due to special types of optical nonlinearity, e.g. caused by electron-hole plasma (EHP) photoexcitation. We propose a highly tunable dielectric nanoantenna consisting of a chain of silicon particles excited by a dipole emitter. The nanoantenna exhibits slow group-velocity guided modes, corresponding to the Van Hove singularity in an infinite structure, which enable a large Purcell factor up to several hundred and are very sensitive to the nanoparticle permittivity. This sensitivity enables the nanoantenna tuning via EHP excitation with an ultrafast laser pumping. Dramatic variations in the nanoantenna radiation patterns and Purcell factor caused by ultrafast laser pumping of several boundary nanoparticles with relatively low intensities of about 25 GW /cm2 are shown. Unidirectional surface-plasmon polaritons launching with EHP excitation in the nanoantenna on a Ag substrate is demonstrated.

Alternatives Assessment Frameworks: Research Needs for the Informed Substitution of Hazardous Chemicals

PubMed Central

Jacobs, Molly M.; Malloy, Timothy F.; Tickner, Joel A.; Edwards, Sally

2015-01-01

Background Given increasing pressures for hazardous chemical replacement, there is growing interest in alternatives assessment to avoid substituting a toxic chemical with another of equal or greater concern. Alternatives assessment is a process for identifying, comparing, and selecting safer alternatives to chemicals of concern (including those used in materials, processes, or technologies) on the basis of their hazards, performance, and economic viability. Objectives The purposes of this substantive review of alternatives assessment frameworks are to identify consistencies and differences in methods and to outline needs for research and collaboration to advance science policy practice. Methods This review compares methods used in six core components of these frameworks: hazard assessment, exposure characterization, life-cycle impacts, technical feasibility evaluation, economic feasibility assessment, and decision making. Alternatives assessment frameworks published from 1990 to 2014 were included. Results Twenty frameworks were reviewed. The frameworks were consistent in terms of general process steps, but some differences were identified in the end points addressed. Methodological gaps were identified in the exposure characterization, life-cycle assessment, and decision–analysis components. Methods for addressing data gaps remain an issue. Discussion Greater consistency in methods and evaluation metrics is needed but with sufficient flexibility to allow the process to be adapted to different decision contexts. Conclusion Although alternatives assessment is becoming an important science policy field, there is a need for increased cross-disciplinary collaboration to refine methodologies in support of the informed substitution and design of safer chemicals, materials, and products. Case studies can provide concrete lessons to improve alternatives assessment. Citation Jacobs MM, Malloy TF, Tickner JA, Edwards S. 2016. Alternatives assessment frameworks: research needs for the informed substitution of hazardous chemicals. Environ Health Perspect 124:265–280; http://dx.doi.org/10.1289/ehp.1409581 PMID:26339778

Children’s Health in Latin America: The Influence of Environmental Exposures

PubMed Central

Laborde, Amalia; Tomasina, Fernando; Bianchi, Fabrizio; Bruné, Marie-Noel; Buka, Irena; Comba, Pietro; Corra, Lilian; Cori, Liliana; Duffert, Christin Maria; Harari, Raul; Iavarone, Ivano; McDiarmid, Melissa A.; Gray, Kimberly A.; Sly, Peter D.; Soares, Agnes; Suk, William A.

2014-01-01

Background Chronic diseases are increasing among children in Latin America. Objective and Methods To examine environmental risk factors for chronic disease in Latin American children and to develop a strategic initiative for control of these exposures, the World Health Organization (WHO) including the Pan American Health Organization (PAHO), the Collegium Ramazzini, and Latin American scientists reviewed regional and relevant global data. Results Industrial development and urbanization are proceeding rapidly in Latin America, and environmental pollution has become widespread. Environmental threats to children’s health include traditional hazards such as indoor air pollution and drinking-water contamination; the newer hazards of urban air pollution; toxic chemicals such as lead, asbestos, mercury, arsenic, and pesticides; hazardous and electronic waste; and climate change. The mix of traditional and modern hazards varies greatly across and within countries reflecting industrialization, urbanization, and socioeconomic forces. Conclusions To control environmental threats to children’s health in Latin America, WHO, including PAHO, will focus on the most highly prevalent and serious hazards—indoor and outdoor air pollution, water pollution, and toxic chemicals. Strategies for controlling these hazards include developing tracking data on regional trends in children’s environmental health (CEH), building a network of Collaborating Centres, promoting biomedical research in CEH, building regional capacity, supporting development of evidence-based prevention policies, studying the economic costs of chronic diseases in children, and developing platforms for dialogue with relevant stakeholders. Citation Laborde A, Tomasina F, Bianchi F, Bruné MN, Buka I, Comba P, Corra L, Cori L, Duffert CM, Harari R, Iavarone I, McDiarmid MA, Gray KA, Sly PD, Soares A, Suk WA, Landrigan PJ. 2015. Children’s health in Latin America: the influence of environmental exposures. Environ Health Perspect 123:201–209; http://dx.doi.org/10.1289/ehp.1408292 PMID:25499717

A combined Cyanex-923/HEH[EHP]/Dodecane solvent for recovery of transuranic elements from used nuclear fuel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, A.; Nash, K.L.

2013-07-01

The separation of minor actinides from fission product lanthanides remains a primary challenge for enabling the recycle of used nuclear fuel. To minimize the complexity of materials handling, combining extractant processes has become an increasingly attractive option. Unfortunately, combined processes sometimes suffer reduced utility due to strong dipole-dipole interactions between the extractants. The results reported here describe a system based on a combination of commercially available extractants Cyanex-923 and HEH[EHP]. In contrast to other combined extractant systems, these extractant molecules exhibit comparatively weak interactions, reducing the impact of secondary interactions. In this process, mixtures containing equal ratios of Cyanex-923 andmore » HEH[EHP] were seen to co-extract americium and the lanthanides from nitric acid solutions. Stripping of An(III) was effectively achieved through contact with an aqueous phase comprised of glycine (for pH control) and a polyamino-poly-carboxylate stripping reagent that selectively removes An(III) from the extractant phase. The lanthanides can then be stripped from the loaded organic phase contacting with high nitric acid concentrations. Extraction of fission products zirconium and molybdenum was also investigated and potential strategies for their management have been identified. The work presented demonstrates the feasibility of combining Cyanex-923 and HEH[EHP] for separating and recovering the transuranic elements from the Ln(III). (authors)« less

Human Health Effects of Biphenyl: Key Findings and Scientific Issues

PubMed Central

Li, Zheng; Hogan, Karen A.; Cai, Christine; Rieth, Susan

2015-01-01

Background: In support of the Integrated Risk Information System (IRIS), the U.S. Environmental Protection Agency (EPA) has evaluated the human health hazards of biphenyl exposure. Objectives: We review key findings and scientific issues regarding expected human health effects of biphenyl. Methods: Scientific literature from 1926 through September 2012 was critically evaluated to identify potential human health hazards associated with biphenyl exposure. Key issues related to the carcinogenicity and noncancer health hazards of biphenyl were examined based on evidence from experimental animal bioassays and mechanistic studies. Discussion: Systematic consideration of experimental animal studies of oral biphenyl exposure took into account the variety of study designs (e.g., study sizes, exposure levels, and exposure durations) to reconcile differing reported results. The available mechanistic and toxicokinetic evidence supports the hypothesis that male rat urinary bladder tumors arise through urinary bladder calculi formation but is insufficient to hypothesize a mode of action for liver tumors in female mice. Biphenyl and its metabolites may induce genetic damage, but a role for genotoxicity in biphenyl-induced carcinogenicity has not been established. Conclusions: The available health effects data for biphenyl provides suggestive evidence for carcinogenicity in humans, based on increased incidences of male rat urinary bladder tumors at high exposure levels and on female mouse liver tumors. Kidney toxicity is also a potential human health hazard of biphenyl exposure. Citation: Li Z, Hogan KA, Cai C, Rieth S. 2016. Human health effects of biphenyl: key findings and scientific issues. Environ Health Perspect 124:703–712; http://dx.doi.org/10.1289/ehp.1509730 PMID:26529796

Assessment of accuracy, fix success rate, and use of estimated horizontal position error (EHPE) to filter inaccurate data collected by a common commercially available GPS logger.

PubMed

Morris, Gail; Conner, L Mike

2017-01-01

Global positioning system (GPS) technologies have improved the ability of researchers to monitor wildlife; however, use of these technologies is often limited by monetary costs. Some researchers have begun to use commercially available GPS loggers as a less expensive means of tracking wildlife, but data regarding performance of these devices are limited. We tested a commercially available GPS logger (i-gotU GT-120) by placing loggers at ground control points with locations known to < 30 cm. In a preliminary investigation, we collected locations every 15 minutes for several days to estimate location error (LE) and circular error probable (CEP). Using similar methods, we then investigated the influence of cover on LE, CEP, and fix success rate (FSR) by constructing cover over ground control points. We found mean LE was < 10 m and mean 50% CEP was < 7 m. FSR was not significantly influenced by cover and in all treatments remained near 100%. Cover had a minor but significant effect on LE. Denser cover was associated with higher mean LE, but the difference in LE between the no cover and highest cover treatments was only 2.2 m. Finally, the most commonly used commercially available devices provide a measure of estimated horizontal position error (EHPE) which potentially may be used to filter inaccurate locations. Using data combined from the preliminary and cover investigations, we modeled LE as a function of EHPE and number of satellites. We found support for use of both EHPE and number of satellites in predicting LE; however, use of EHPE to filter inaccurate locations resulted in the loss of many locations with low error in return for only modest improvements in LE. Even without filtering, the accuracy of the logger was likely sufficient for studies which can accept average location errors of approximately 10 m.

Does Aerosol Weaken or Strengthen the South Asian Monsoon?

NASA Technical Reports Server (NTRS)

Lau, William K. M.

2007-01-01

Aerosols are known to have the ability to block off solar radiation reaching the earth surface, causing it to cool - the so-called solar dimming (SDM) effect. In the Asian monsoon region, the SDM effect by aerosol can produce differential cooling at the surface reducing the meridional thermal contrast between land and ocean, leading to a weakening of the monsoon (Ramanathan et al. 2005). On the other hand, absorbing aerosols such as black carbon and dust, when forced up against the steep slopes of the southern Tibetan Plateau can produce upper tropospheric heating, and induce convection-dynamic feedback leading to an advance of the rainy season over northern India and an enhancement of the South Asian monsoon through the "Elevated Heat Pump" (EHP) effect (Lau et al. 2006). In this paper, we present modeling results showing that in a coupled ocean-atmosphere-land system in which concentrations of greenhouse gases are kept constant, the response of the South Asian monsoon to dust and black carbon forcing is the net result of the two opposing effects of SDM and EHP. For the South Asian monsoon, if the increasing upper tropospheric thermal contrast between the Tibetan Plateau and region to the south spurred by the EHP overwhelms the reduction in surface temperature contrast due to SDM, the monsoon strengthens. Otherwise, the monsoon weakens. Preliminary observations are consistent with the above findings. We find that the two effects are strongly scale dependent. On interannual and shorter time scales, the EHP effect appears to dominate in the early summer season (May-June). On decadal or longer time scales, the SDM dominates for the mature monsoon (July-August). Better understanding the physical mechanisms underlying the SDM and the EHP effects, the local emission and transport of aerosols from surrounding deserts and arid-regions, and their interaction with monsoon water cycle dynamics are important in providing better prediction and assessment of climate change impacts on precipitation of the Asian monsoon land regions.

Does Aerosol Weaken or Strengthen the South Asian Monsoon?

NASA Technical Reports Server (NTRS)

Lau, William K.

2010-01-01

Aerosols are known to have the ability to block off solar radiation reaching the earth surface, causing it to cool - the so-called solar dimming (SDM) effect. In the Asian monsoon region, the SDM effect by aerosol can produce differential cooling at the surface reducing the meridional thermal contrast between land and ocean, leading to a weakening of the monsoon. On the other hand, absorbing aerosols such as black carbon and dust, when forced up against the steep slopes of the southern Tibetan Plateau can produce upper tropospheric heating, and induce convection-dynamic feedback leading to an advance of the rainy season over northern India and an enhancement of the South Asian monsoon through the "Elevated Heat Pump" (EHP) effect. In this paper, we present modeling results showing that in a coupled ocean-atmosphere-land system in which concentrations of greenhouse gases are kept constant, the response of the South Asian monsoon to dust and black carbon forcing is the net result of the two opposing effects of SDM and EHP. For the South Asian monsoon, if the increasing upper tropospheric thermal contrast between the Tibetan Plateau and region to the south spurred by the EHP overwhelms the reduction in surface temperature contrast due to SDM, the monsoon strengthens. Otherwise, the monsoon weakens. Preliminary observations are consistent with the above findings. We find that the two effects are strongly scale dependent. On interannual and shorter time scales, the EHP effect appears to dominate in the early summer season (May-June). On decadal or longer time scales, the SDM dominates for the mature monsoon (July-August). Better understanding the physical mechanisms underlying the SDM and the EHP effects, the local emission and transport of aerosols from surrounding deserts and arid-regions, and their interaction with monsoon water cycle dynamics are important in providing better prediction and assessment of climate change impacts on precipitation of the Asian monsoon land regions.

[Quality of life after deep pelvic endometriosis surgery: Evaluation of a French version of the EHP-30].

PubMed

Selvi Dogan, F; Cottenet, J; Douvier, S; Sagot, P

2016-03-01

To evaluate the changes in the quality of life of patients after deep pelvic endometriosis surgery, with a French version of EHP-30 questionnaire, and the capacity of the EHP-30 to carry out this measurement. Study prospective monocentric, conducted in the obstetrics and gynecology department of the CHU Dijon during the period of October 2012 from October 2013. A EHP-30 questionnaire was given to patients before surgery. The same questionnaire was sent to their homes, away from surgery (3-6 months) to inform about their postoperative quality of life. The difference in preoperative and postoperative scores was tested using the test Wilcoxon signed ranks. A difference was considered significant if the p-value was less than or equal to 0.05. Sensitivity to change was calculated by the method of effect size (ES). The size of the effect is defined as the difference in mean preoperative and postoperative scores divided by the standard deviation of preoperative scores. A size effet of 0.20 indicates less change scores, of 0.50 a moderate change and of 0.80 a material change. We included 22 patients in total in the prospective analysis. The majority of patients had gynecological symptoms of dysmenorrhea with 69.7%, 75.7% and 75.7% dyspareunia chronic pelvic pain. Nineteen patients (57.6%) had gastro-intestinal symptoms. Urinary symptoms were less frequent. The results of the EHP-30 showed a significant improvement for the items "pain" (P=0.01), "control and powerlessness" (P=0.02), "emotional well-being" (P<0,01) "social relations" (P<0.01), "sexual intercourse" (P=0.03) and "relationship with the medical world" (P=0.05). We observed a non-significant improvement for the items "self-image" (P=0.44), "work" (P=0.48) and "relationships with children" (P=0.50). The size of the effect (ES) was low to high for all dimensions of the questionnaire, ranging from 0.1 to 0.6 for the entire group. A significant sensitivity to change was found for the items "pain" (ES=0.60), "control and powerlessness" (ES=0.62), "social relations" (ES=0.57). A moderate sensitivity to change was found for the items "emotional well-being" (ES=0.29), "relationship with the medical world" (ES=0.26). A low sensitivity to change was found for the items "relationships with children" (ES=0.06), "self-image" (ES=0.16), "work" (ES=0.18), "sexual intercourse" (ES=0.20). A size that is important to moderate effect corresponded to a statistically significant improvement of the score EHP-30. This study showed that the EHP-30 is a sensitive tool to change the health status and an appropriate instrument for the assessment of treatment effects in patients with deep pelvic endometriosis. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Serum Vitamin D and Risk of Breast Cancer within Five Years.

PubMed

O'Brien, Katie M; Sandler, Dale P; Taylor, Jack A; Weinberg, Clarice R

2017-07-06

Vitamin D is an environmental and dietary agent with known anticarcinogenic effects, but protection against breast cancer has not been established. We evaluated the association between baseline serum 25-hydroxyvitamin D [25(OH)D] levels, supplemental vitamin D use, and breast cancer incidence over the subsequent 5 y of follow-up. From 2003-2009, the Sister Study enrolled 50,884 U.S. women 35-74 y old who had a sister with breast cancer but had never had breast cancer themselves. Using liquid chromatography-mass spectrometry, we measured 25(OH)D in serum samples from 1,611 women who later developed breast cancer and from 1,843 randomly selected cohort participants. We estimated hazard ratios (HRs) and 95% confidence intervals (CIs) for the risk of developing breast cancer using Cox proportional hazards models. We found that 25(OH)D levels were associated with a 21% lower breast cancer hazard (highest versus lowest quartile: adjusted ; CI: 0.63, 0.98). Analysis of the first 5 y of follow-up for all 50,884 Sister Study participants showed that self-reported vitamin D supplementation was associated with an 11% lower hazard [ (CI: 0.81, 0.99)]. These associations were particularly strong among postmenopausal women [ (CI: 0.57, 0.93) and (CI: 0.74, 0.93), respectively]. In this cohort of women with elevated risk, high serum 25(OH)D levels and regular vitamin D supplement use were associated with lower rates of incident, postmenopausal breast cancer over 5 y of follow-up. These results may help to establish clinical benchmarks for 25(OH)D levels; in addition, they support the hypothesis that vitamin D supplementation is useful in breast cancer prevention. https://doi.org/10.1289/EHP943.

Prioritizing Chemicals for Risk Assessment Using Chemoinformatics: Examples from the IARC Monographs on Pesticides.

PubMed

Guha, Neela; Guyton, Kathryn Z; Loomis, Dana; Barupal, Dinesh Kumar

2016-12-01

Identifying cancer hazards is the first step towards cancer prevention. The International Agency for Research on Cancer (IARC) Monographs Programme, which has evaluated nearly 1,000 agents for their carcinogenic potential since 1971, typically selects agents for hazard identification on the basis of public nominations, expert advice, published data on carcinogenicity, and public health importance. Here, we present a novel and complementary strategy for identifying agents for hazard evaluation using chemoinformatics, database integration, and automated text mining. To inform selection among a broad range of pesticides nominated for evaluation, we identified and screened nearly 6,000 relevant chemical structures, after which we systematically compiled information on 980 pesticides, creating network maps that allowed cluster visualization by chemical similarity, pesticide class, and publicly available information concerning cancer epidemiology, cancer bioassays, and carcinogenic mechanisms. For the IARC Monograph meetings that took place in March and June 2015, this approach supported high-priority evaluation of glyphosate, malathion, parathion, tetrachlorvinphos, diazinon, p,p'-dichlorodiphenyltrichloroethane (DDT), lindane, and 2,4-dichlorophenoxyacetic acid (2,4-D). This systematic approach, accounting for chemical similarity and overlaying multiple data sources, can be used by risk assessors as well as by researchers to systematize, inform, and increase efficiency in selecting and prioritizing agents for hazard identification, risk assessment, regulation, or further investigation. This approach could be extended to an array of outcomes and agents, including occupational carcinogens, drugs, and foods. Citation: Guha N, Guyton KZ, Loomis D, Barupal DK. 2016. Prioritizing chemicals for risk assessment using chemoinformatics: examples from the IARC Monographs on Pesticides. Environ Health Perspect 124:1823-1829; http://dx.doi.org/10.1289/EHP186.

Prioritizing Chemicals for Risk Assessment Using Chemoinformatics: Examples from the IARC Monographs on Pesticides

PubMed Central

Guha, Neela; Guyton, Kathryn Z.; Loomis, Dana; Barupal, Dinesh Kumar

2016-01-01

Background: Identifying cancer hazards is the first step towards cancer prevention. The International Agency for Research on Cancer (IARC) Monographs Programme, which has evaluated nearly 1,000 agents for their carcinogenic potential since 1971, typically selects agents for hazard identification on the basis of public nominations, expert advice, published data on carcinogenicity, and public health importance. Objectives: Here, we present a novel and complementary strategy for identifying agents for hazard evaluation using chemoinformatics, database integration, and automated text mining. Discussion: To inform selection among a broad range of pesticides nominated for evaluation, we identified and screened nearly 6,000 relevant chemical structures, after which we systematically compiled information on 980 pesticides, creating network maps that allowed cluster visualization by chemical similarity, pesticide class, and publicly available information concerning cancer epidemiology, cancer bioassays, and carcinogenic mechanisms. For the IARC Monograph meetings that took place in March and June 2015, this approach supported high-priority evaluation of glyphosate, malathion, parathion, tetrachlorvinphos, diazinon, p,p′-dichlorodiphenyltrichloroethane (DDT), lindane, and 2,4-dichlorophenoxyacetic acid (2,4-D). Conclusions: This systematic approach, accounting for chemical similarity and overlaying multiple data sources, can be used by risk assessors as well as by researchers to systematize, inform, and increase efficiency in selecting and prioritizing agents for hazard identification, risk assessment, regulation, or further investigation. This approach could be extended to an array of outcomes and agents, including occupational carcinogens, drugs, and foods. Citation: Guha N, Guyton KZ, Loomis D, Barupal DK. 2016. Prioritizing chemicals for risk assessment using chemoinformatics: examples from the IARC Monographs on Pesticides. Environ Health Perspect 124:1823–1829; http://dx.doi.org/10.1289/EHP186 PMID:27164621

Population-Based in Vitro Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study

PubMed Central

Abdo, Nour; Xia, Menghang; Brown, Chad C.; Kosyk, Oksana; Huang, Ruili; Sakamuru, Srilatha; Zhou, Yi-Hui; Jack, John R.; Gallins, Paul; Xia, Kai; Li, Yun; Chiu, Weihsueh A.; Motsinger-Reif, Alison A.; Austin, Christopher P.; Tice, Raymond R.

2015-01-01

Background: Understanding of human variation in toxicity to environmental chemicals remains limited, so human health risk assessments still largely rely on a generic 10-fold factor (10½ each for toxicokinetics and toxicodynamics) to account for sensitive individuals or subpopulations. Objectives: We tested a hypothesis that population-wide in vitro cytotoxicity screening can rapidly inform both the magnitude of and molecular causes for interindividual toxicodynamic variability. Methods: We used 1,086 lymphoblastoid cell lines from the 1000 Genomes Project, representing nine populations from five continents, to assess variation in cytotoxic response to 179 chemicals. Analysis included assessments of population variation and heritability, and genome-wide association mapping, with attention to phenotypic relevance to human exposures. Results: For about half the tested compounds, cytotoxic response in the 1% most “sensitive” individual occurred at concentrations within a factor of 10½ (i.e., approximately 3) of that in the median individual; however, for some compounds, this factor was > 10. Genetic mapping suggested important roles for variation in membrane and transmembrane genes, with a number of chemicals showing association with SNP rs13120371 in the solute carrier SLC7A11, previously implicated in chemoresistance. Conclusions: This experimental approach fills critical gaps unaddressed by recent large-scale toxicity testing programs, providing quantitative, experimentally based estimates of human toxicodynamic variability, and also testable hypotheses about mechanisms contributing to interindividual variation. Citation: Abdo N, Xia M, Brown CC, Kosyk O, Huang R, Sakamuru S, Zhou YH, Jack JR, Gallins P, Xia K, Li Y, Chiu WA, Motsinger-Reif AA, Austin CP, Tice RR, Rusyn I, Wright FA. 2015. Population-based in vitro hazard and concentration–response assessment of chemicals: the 1000 Genomes high-throughput screening study. Environ Health Perspect 123:458–466; http://dx.doi.org/10.1289/ehp.1408775 PMID:25622337

Dissolved organic phosphorus speciation in the waters of the Tamar estuary (SW England)

NASA Astrophysics Data System (ADS)

Monbet, Phil; McKelvie, Ian D.; Worsfold, Paul J.

2009-02-01

The speciation of dissolved organic phosphorus (DOP) in the temperate Tamar estuary of SW England is described. Eight stations from the riverine to marine end-members were sampled during four seasonal campaigns in 2007 and the DOP pool in the water column and sediment porewater was characterized and quantified using a flow injection manifold after sequential enzymatic hydrolysis. This enabled the enzymatically hydrolysable phosphorus (EHP) fraction and its component labile monoester phosphates, diester phosphates and a phytase-hydrolysable fraction that includes myo-inositol hexakisphosphate (phytic acid), to be determined and compared with the total DOP, dissolved reactive phosphorus (DRP) and total dissolved phosphorus (TDP) pools. The results showed that the DOP pool in the water column varied temporally and spatially within the estuary (1.1-22 μg L -1) and constituted 6-40% of TDP. The EHP fraction of DOP ranged from 1.1-15 μg L -1 and represented a significant and potentially bioavailable phosphorus fraction. Furthermore the spatial profiles of the three components of the EHP pool generally showed non-conservative behavior along the salinity gradient, with apparent internal estuarine sources. Porewater profiles followed broadly similar trends but were notably higher at the marine station throughout the year. In contrast to soil organic phosphorus profiles, the labile monoester phosphate fraction was the largest component, with diester phosphates also prevalent. Phytic acid concentrations were higher in the lower estuary, possibly due to salinity induced desorption processes. The EHP fraction is not commonly determined in aquatic systems due to the lack of a suitable measurement technique and the Tamar results reported here have important implications for phosphorus biogeochemistry, estuarine ecology and the development of efficient strategies for limiting the effects of phosphorus on water quality.

77 FR 59879 - Idaho: Incorporation by Reference of Approved State Hazardous Waste Management Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-01

...: Incorporation by Reference of Approved State Hazardous Waste Management Program AGENCY: Environmental Protection... ``Approved State Hazardous Waste Management Programs,'' Idaho's authorized hazardous waste program. The EPA... Federal Register, the EPA is codifying and incorporating by reference the State's hazardous waste program...

The Global Food System as a Transport Pathway for Hazardous Chemicals: The Missing Link between Emissions and Exposure.

PubMed

Ng, Carla A; von Goetz, Natalie

2017-01-01

Food is a major pathway for human exposure to hazardous chemicals. The modern food system is becoming increasingly complex and globalized, but models for food-borne exposure typically assume locally derived diets or use concentrations directly measured in foods without accounting for food origin. Such approaches may not reflect actual chemical intakes because concentrations depend on food origin, and representative analysis is seldom available. Processing, packaging, storage, and transportation also impart different chemicals to food and are not yet adequately addressed. Thus, the link between environmental emissions and realistic human exposure is effectively broken. We discuss the need for a fully integrated treatment of the modern industrialized food system, and we propose strategies for using existing models and relevant supporting data sources to track chemicals during production, processing, packaging, storage, and transport. Fate and bioaccumulation models describe how chemicals distribute in the environment and accumulate through local food webs. Human exposure models can use concentrations in food to determine body burdens based on individual or population characteristics. New models now include the impacts of processing and packaging but are far from comprehensive. We propose to close the gap between emissions and exposure by utilizing a wider variety of models and data sources, including global food trade data, processing, and packaging models. A comprehensive approach that takes into account the complexity of the modern global food system is essential to enable better prediction of human exposure to chemicals in food, sound risk assessments, and more focused risk abatement strategies. Citation: Ng CA, von Goetz N. 2017. The global food system as a transport pathway for hazardous chemicals: the missing link between emissions and exposure. Environ Health Perspect 125:1-7; http://dx.doi.org/10.1289/EHP168.

Secondary use of data from hospital electronic prescribing and pharmacy systems to support the quality and safety of antimicrobial use: a systematic review.

PubMed

Micallef, Christianne; Chaudhry, Navila T; Holmes, Alison H; Hopkins, Susan; Benn, Jonathan; Franklin, Bryony Dean

2017-07-01

Electronic prescribing (EP) and electronic hospital pharmacy (EHP) systems are increasingly common. A potential benefit is the extensive data in these systems that could be used to support antimicrobial stewardship, but there is little information on how such data are currently used to support the quality and safety of antimicrobial use. To summarize the literature on secondary use of data (SuD) from EP and EHP systems to support quality and safety of antimicrobial use, to describe any barriers to secondary use and to make recommendations for future work in this field. We conducted a systematic search within four databases; we included original research studies that were (1) based on SuD from hospital EP or EHP systems and (2) reported outcomes relating to quality and/or safety of antimicrobial use and/or qualitative findings relating to SuD in this context. Ninety-four full-text articles were obtained; 14 met our inclusion criteria. Only two described interventions based on SuD; seven described SuD to evaluate other antimicrobial stewardship interventions and five described descriptive or exploratory studies of potential applications of SuD. Types of data used were quantitative antibiotic usage data ( n  =   9 studies), dose administration data ( n  =   4) and user log data from an electronic dashboard ( n  = 1). Barriers included data access, data accuracy and completeness, and complexity when using data from multiple systems or hospital sites. The literature suggests that SuD from EP and EHP systems is potentially useful to support or evaluate antimicrobial stewardship activities; greater system functionality would help to realize these benefits. © The Author 2017. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Environmental Remediation to Address Childhood Lead Poisoning Epidemic due to Artisanal Gold Mining in Zamfara, Nigeria

PubMed Central

Tirima, Simba; Bartrem, Casey; von Lindern, Ian; von Braun, Margrit; Lind, Douglas; Anka, Shehu Mohammed; Abdullahi, Aishat

2016-01-01

Background: From 2010 through 2013, integrated health and environmental responses addressed an unprecedented epidemic lead poisoning in Zamfara State, northern Nigeria. Artisanal gold mining caused widespread contamination resulting in the deaths of > 400 children. Socioeconomic, logistic, and security challenges required remediation and medical protocols within the context of local resources, labor practices, and cultural traditions. Objectives: Our aim was to implement emergency environmental remediation to abate exposures to 17,000 lead poisoned villagers, to facilitate chelation treatment of children ≤ 5 years old, and to establish local technical capacity and lead health advocacy programs to prevent future disasters. Methods: U.S. hazardous waste removal protocols were modified to accommodate local agricultural practices. Remediation was conducted over 4 years in three phases, progressing from an emergency response by international personnel to comprehensive cleanup funded and accomplished by the Nigerian government. Results: More than 27,000 m3 of contaminated soils and mining waste were removed from 820 residences and ore processing areas in eight villages, largely by hand labor, and disposed in constructed landfills. Excavated areas were capped with clean soils (≤ 25 mg/kg lead), decreasing soil lead concentrations by 89%, and 2,349 children received chelation treatment. Pre-chelation geometric mean blood lead levels for children ≤ 5 years old decreased from 149 μg/dL to 15 μg/dL over the 4-year remedial program. Conclusions: The unprecedented outbreak and response demonstrate that, given sufficient political will and modest investment, the world’s most challenging environmental health crises can be addressed by adapting proven response protocols to the capabilities of host countries. Citation: Tirima S, Bartrem C, von Lindern I, von Braun M, Lind D, Anka SM, Abdullahi A. 2016. Environmental remediation to address childhood lead poisoning epidemic due to artisanal gold mining in Zamfara, Nigeria. Environ Health Perspect 124:1471–1478; http://dx.doi.org/10.1289/ehp.1510145 PMID:26745642

Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis

PubMed Central

Smith, Martyn T.; Guyton, Kathryn Z.; Gibbons, Catherine F.; Fritz, Jason M.; Portier, Christopher J.; Rusyn, Ivan; DeMarini, David M.; Caldwell, Jane C.; Kavlock, Robert J.; Lambert, Paul F.; Hecht, Stephen S.; Bucher, John R.; Stewart, Bernard W.; Baan, Robert A.; Cogliano, Vincent J.; Straif, Kurt

2015-01-01

Background: A recent review by the International Agency for Research on Cancer (IARC) updated the assessments of the > 100 agents classified as Group 1, carcinogenic to humans (IARC Monographs Volume 100, parts A–F). This exercise was complicated by the absence of a broadly accepted, systematic method for evaluating mechanistic data to support conclusions regarding human hazard from exposure to carcinogens. Objectives and Methods: IARC therefore convened two workshops in which an international Working Group of experts identified 10 key characteristics, one or more of which are commonly exhibited by established human carcinogens. Discussion: These characteristics provide the basis for an objective approach to identifying and organizing results from pertinent mechanistic studies. The 10 characteristics are the abilities of an agent to 1) act as an electrophile either directly or after metabolic activation; 2) be genotoxic; 3) alter DNA repair or cause genomic instability; 4) induce epigenetic alterations; 5) induce oxidative stress; 6) induce chronic inflammation; 7) be immunosuppressive; 8) modulate receptor-mediated effects; 9) cause immortalization; and 10) alter cell proliferation, cell death, or nutrient supply. Conclusion: We describe the use of the 10 key characteristics to conduct a systematic literature search focused on relevant end points and construct a graphical representation of the identified mechanistic information. Next, we use benzene and polychlorinated biphenyls as examples to illustrate how this approach may work in practice. The approach described is similar in many respects to those currently being implemented by the U.S. EPA’s Integrated Risk Information System Program and the U.S. National Toxicology Program. Citation: Smith MT, Guyton KZ, Gibbons CF, Fritz JM, Portier CJ, Rusyn I, DeMarini DM, Caldwell JC, Kavlock RJ, Lambert P, Hecht SS, Bucher JR, Stewart BW, Baan R, Cogliano VJ, Straif K. 2016. Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis. Environ Health Perspect 124:713–721; http://dx.doi.org/10.1289/ehp.1509912 PMID:26600562

Environmental Remediation to Address Childhood Lead Poisoning Epidemic due to Artisanal Gold Mining in Zamfara, Nigeria.

PubMed

Tirima, Simba; Bartrem, Casey; von Lindern, Ian; von Braun, Margrit; Lind, Douglas; Anka, Shehu Mohammed; Abdullahi, Aishat

2016-09-01

From 2010 through 2013, integrated health and environmental responses addressed an unprecedented epidemic lead poisoning in Zamfara State, northern Nigeria. Artisanal gold mining caused widespread contamination resulting in the deaths of > 400 children. Socioeconomic, logistic, and security challenges required remediation and medical protocols within the context of local resources, labor practices, and cultural traditions. Our aim was to implement emergency environmental remediation to abate exposures to 17,000 lead poisoned villagers, to facilitate chelation treatment of children ≤ 5 years old, and to establish local technical capacity and lead health advocacy programs to prevent future disasters. U.S. hazardous waste removal protocols were modified to accommodate local agricultural practices. Remediation was conducted over 4 years in three phases, progressing from an emergency response by international personnel to comprehensive cleanup funded and accomplished by the Nigerian government. More than 27,000 m3 of contaminated soils and mining waste were removed from 820 residences and ore processing areas in eight villages, largely by hand labor, and disposed in constructed landfills. Excavated areas were capped with clean soils (≤ 25 mg/kg lead), decreasing soil lead concentrations by 89%, and 2,349 children received chelation treatment. Pre-chelation geometric mean blood lead levels for children ≤ 5 years old decreased from 149 μg/dL to 15 μg/dL over the 4-year remedial program. The unprecedented outbreak and response demonstrate that, given sufficient political will and modest investment, the world's most challenging environmental health crises can be addressed by adapting proven response protocols to the capabilities of host countries. Tirima S, Bartrem C, von Lindern I, von Braun M, Lind D, Anka SM, Abdullahi A. 2016. Environmental remediation to address childhood lead poisoning epidemic due to artisanal gold mining in Zamfara, Nigeria. Environ Health Perspect 124:1471-1478; http://dx.doi.org/10.1289/ehp.1510145.

Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis.

PubMed

Smith, Martyn T; Guyton, Kathryn Z; Gibbons, Catherine F; Fritz, Jason M; Portier, Christopher J; Rusyn, Ivan; DeMarini, David M; Caldwell, Jane C; Kavlock, Robert J; Lambert, Paul F; Hecht, Stephen S; Bucher, John R; Stewart, Bernard W; Baan, Robert A; Cogliano, Vincent J; Straif, Kurt

2016-06-01

A recent review by the International Agency for Research on Cancer (IARC) updated the assessments of the > 100 agents classified as Group 1, carcinogenic to humans (IARC Monographs Volume 100, parts A-F). This exercise was complicated by the absence of a broadly accepted, systematic method for evaluating mechanistic data to support conclusions regarding human hazard from exposure to carcinogens. IARC therefore convened two workshops in which an international Working Group of experts identified 10 key characteristics, one or more of which are commonly exhibited by established human carcinogens. These characteristics provide the basis for an objective approach to identifying and organizing results from pertinent mechanistic studies. The 10 characteristics are the abilities of an agent to 1) act as an electrophile either directly or after metabolic activation; 2) be genotoxic; 3) alter DNA repair or cause genomic instability; 4) induce epigenetic alterations; 5) induce oxidative stress; 6) induce chronic inflammation; 7) be immunosuppressive; 8) modulate receptor-mediated effects; 9) cause immortalization; and 10) alter cell proliferation, cell death, or nutrient supply. We describe the use of the 10 key characteristics to conduct a systematic literature search focused on relevant end points and construct a graphical representation of the identified mechanistic information. Next, we use benzene and polychlorinated biphenyls as examples to illustrate how this approach may work in practice. The approach described is similar in many respects to those currently being implemented by the U.S. EPA's Integrated Risk Information System Program and the U.S. National Toxicology Program. Smith MT, Guyton KZ, Gibbons CF, Fritz JM, Portier CJ, Rusyn I, DeMarini DM, Caldwell JC, Kavlock RJ, Lambert P, Hecht SS, Bucher JR, Stewart BW, Baan R, Cogliano VJ, Straif K. 2016. Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis. Environ Health Perspect 124:713-721; http://dx.doi.org/10.1289/ehp.1509912.

Scientific Challenges in the Risk Assessment of Food Contact Materials.

PubMed

Muncke, Jane; Backhaus, Thomas; Geueke, Birgit; Maffini, Maricel V; Martin, Olwenn Viviane; Myers, John Peterson; Soto, Ana M; Trasande, Leonardo; Trier, Xenia; Scheringer, Martin

2017-09-11

Food contact articles (FCAs) are manufactured from food contact materials (FCMs) that include plastics, paper, metal, glass, and printing inks. Chemicals can migrate from FCAs into food during storage, processing, and transportation. Food contact materials' safety is evaluated using chemical risk assessment (RA). Several challenges to the RA of FCAs exist. We review regulatory requirements for RA of FCMs in the United States and Europe, identify gaps in RA, and highlight opportunities for improving the protection of public health. We intend to initiate a discussion in the wider scientific community to enhance the safety of food contact articles. Based on our evaluation of the evidence, we conclude that current regulations are insufficient for addressing chemical exposures from FCAs. RA currently focuses on monomers and additives used in the manufacture of products, but it does not cover all substances formed in the production processes. Several factors hamper effective RA for many FCMs, including a lack of information on chemical identity, inadequate assessment of hazardous properties, and missing exposure data. Companies make decisions about the safety of some food contact chemicals (FCCs) without review by public authorities. Some chemical migration limits cannot be enforced because analytical standards are unavailable. We think that exposures to hazardous substances migrating from FCAs require more attention. We recommend a ) limiting the number and types of chemicals authorized for manufacture and b ) developing novel approaches for assessing the safety of chemicals in FCAs, including unidentified chemicals that form during or after production. https://doi.org/10.1289/EHP644.

Evaluating ligands for use in polymer ligand film (PLF) for plutonium and uranium extraction

DOE PAGES

Rim, Jung H.; Peterson, Dominic S.; Armenta, Claudine E.; ...

2015-05-08

We describe a new analyte extraction technique using Polymer Ligand Film (PLF). PLFs were synthesized to perform direct sorption of analytes onto its surface for direct counting using alpha spectroscopy. The main focus of the new technique is to shorten and simplify the procedure for chemically isolating radionuclides for determination through a radiometric technique. 4'(5')-di-t-butylcyclohexano 18-crown-6 (DtBuCH 18C 6) and 2-ethylhexylphosphonic acid (HEH[EHP]) were examined for plutonium extraction. Di(2-ethyl hexyl) phosphoric acid (HDEHP) were examined for plutonium and uranium extraction. DtBuCH 18C 6 and HEH[EHP] were not effective in plutonium extraction. HDEHP PLFs were effective for plutonium but not formore » uranium.« less

77 FR 46994 - Oklahoma: Incorporation by Reference of State Hazardous Waste Management Program

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2012-08-07

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77 FR 29275 - Oklahoma: Incorporation by Reference of State Hazardous Waste Management Program

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75 FR 36609 - Oklahoma: Incorporation by Reference of State Hazardous Waste Management Program

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2010-06-28

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77 FR 55371 - System Safety Program

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2012-09-07

...-based rule and FRA seeks comments on all aspects of the proposed rule. An SSP would be implemented by a... SSP would be the risk-based hazard management program and risk-based hazard analysis. A properly implemented risk-based hazard management program and risk-based hazard analysis would identify the hazards and...

75 FR 76691 - Oregon; Correction of Federal Authorization of the State's Hazardous Waste Management Program

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2010-12-09

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75 FR 918 - Oregon: Final Authorization of State Hazardous Waste Management Program Revision

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77 FR 75441 - Healthy Home and Lead Hazard Control Grant Programs Data Collection; Progress Reporting

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2012-12-20

... DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT [Docket No. FR-5603-N-93] Healthy Home and Lead Hazard... collection is designed to provide HUD timely information on progress of Healthy Homes Demonstration Program, Healthy Homes Technical Studies Program, Lead Base paint Hazard Control program, Lead Hazard Reduction...

78 FR 25678 - Georgia: Final Authorization of State Hazardous Waste Management Program Revisions

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76 FR 6594 - Florida: Final Authorization of State Hazardous Waste Management Program Revisions

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76 FR 70408 - Information Collection; Understanding Value Trade-Offs Regarding Fire Hazard Reduction Programs...

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78 FR 25579 - Georgia: Final Authorization of State Hazardous Waste Management Program Revisions

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77 FR 3224 - New Mexico: Incorporation by Reference of State Hazardous Waste Management Program

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2012-01-23

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76 FR 6561 - North Carolina: Final Authorization of State Hazardous Waste Management Program Revisions

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Engineering Geology | Alaska Division of Geological & Geophysical Surveys

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in Highway and development of avalanche susceptibility and prediction models near Atigun Pass. Alaska coastal

78 FR 38730 - Announcement of Funding Awards for Lead-Based Paint Hazard Control, and Lead Hazard Reduction...

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2013-06-27

... Awards for Lead-Based Paint Hazard Control, and Lead Hazard Reduction Demonstration Grant Programs for... (OHHLHC) Lead-Based Paint Hazard Control, and Lead Hazard Reduction Demonstration Grant Program Notices of... Grants.gov on December 3, 2012, and amended on January 18, 2013, for the Lead Based Paint Hazard Control...

77 FR 19306 - Announcement of Funding Awards: Office of Healthy Homes and Lead Hazard Control Grant Programs...

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2012-03-30

... Federal Register notice published on May 18, 2011 for Lead Based Paint Hazard Control and Lead Hazard... Based Paint Hazard Control Grant Program A total of $43,206,000 was awarded to 22 grantees for the Lead Based Paint Hazard Control Grant Program and an additional $1,999,971 was awarded to 20 out of the 29...

77 FR 19305 - Announcement of Funding Awards: Office of Healthy Homes and Lead Hazard Control Grant Programs...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-30

... Federal Register notice published on September 9, 2010 for Lead Based Paint Hazard Control and Lead Hazard... follows: 1. Lead Based Paint Hazard Control Grant Program A total of $69,700,000 was awarded to 29 grantees for the Lead Based Paint Hazard Control Grant Program and an additional $2,388,637 was awarded to...

The Practice of Hatha Yoga for the Treatment of Pain Associated with Endometriosis.

PubMed

Gonçalves, Andrea Vasconcelos; Barros, Nelson Filice; Bahamondes, Luis

2017-01-01

The aim of this study was to compare chronic pelvic pain, menstrual patterns, and quality of life (QoL) in two groups of women with endometriosis: those who did and those who did not participate in a specific 8-week yoga intervention. This was a randomized controlled trial. It was conducted at the University of Campinas Medical School, Campinas, SP, Brazil. Forty women were randomly divided into two groups: an intervention group of women who practiced yoga (n = 28), and a control group of women who did not practice yoga (n = 12). Participants attended 90-min scheduled yoga sessions twice a week for 8 weeks. Additionally, an Endometriosis Health Profile (EHP)-30 questionnaire was applied to evaluate women's QoL at admission and 2 months later upon completion of the yoga program. Menstrual and daily pain patterns were evaluated through a daily calendar (visual analog scale). The degree of daily pain was significantly lower among the women who practiced yoga compared with the non-yoga group (p = 0.0007). There was an improvement of QoL in both groups between baseline and the end of the study evaluation. In relation to EHP-30 domains, pain (p = 0.0046), impotence (p = 0.0006), well-being (p = 0.0009), and image (p = 0.0087) from the central questionnaire, and work (p = 0.0027) and treatment (p = 0.0245) from the modular questionnaire were significantly different between the study groups over time. There was no significant difference between the two groups regarding the diary of menstrual patterns (p = 0.96). Yoga practice was associated with a reduction in levels of chronic pelvic pain and an improvement in QoL in women with endometriosis.

75 FR 45583 - New York: Incorporation by Reference of State Hazardous Waste Management Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-03

... authorized and that EPA will enforce under the Solid Waste Disposal Act, as amended and commonly referred to...: Incorporation by Reference of State Hazardous Waste Management Program AGENCY: Environmental Protection Agency... authorized hazardous waste program which is set forth in the regulations entitled ``Approved State Hazardous...

40 CFR 272.1351 - Montana State-Administered Program: Final Authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Montana § 272.1351... its hazardous waste management program. However, EPA retains the authority to exercise its inspection... this section are incorporated by reference as part of the hazardous waste management program under...

Scientific Challenges in the Risk Assessment of Food Contact Materials

PubMed Central

Backhaus, Thomas; Geueke, Birgit; Maffini, Maricel V.; Martin, Olwenn Viviane; Myers, John Peterson; Soto, Ana M.; Trasande, Leonardo; Trier, Xenia; Scheringer, Martin

2017-01-01

Background: Food contact articles (FCAs) are manufactured from food contact materials (FCMs) that include plastics, paper, metal, glass, and printing inks. Chemicals can migrate from FCAs into food during storage, processing, and transportation. Food contact materials’ safety is evaluated using chemical risk assessment (RA). Several challenges to the RA of FCAs exist. Objectives: We review regulatory requirements for RA of FCMs in the United States and Europe, identify gaps in RA, and highlight opportunities for improving the protection of public health. We intend to initiate a discussion in the wider scientific community to enhance the safety of food contact articles. Discussion: Based on our evaluation of the evidence, we conclude that current regulations are insufficient for addressing chemical exposures from FCAs. RA currently focuses on monomers and additives used in the manufacture of products, but it does not cover all substances formed in the production processes. Several factors hamper effective RA for many FCMs, including a lack of information on chemical identity, inadequate assessment of hazardous properties, and missing exposure data. Companies make decisions about the safety of some food contact chemicals (FCCs) without review by public authorities. Some chemical migration limits cannot be enforced because analytical standards are unavailable. Conclusion: We think that exposures to hazardous substances migrating from FCAs require more attention. We recommend a) limiting the number and types of chemicals authorized for manufacture and b) developing novel approaches for assessing the safety of chemicals in FCAs, including unidentified chemicals that form during or after production. https://doi.org/10.1289/EHP644 PMID:28893723

Hazardous materials programs in the fifty states.

DOT National Transportation Integrated Search

1988-01-01

This report describes the hazardous materials transportation safety programs, laws, and regulatory programs enacted by each of the fifty states. The report contains a brief description of common elements in the hazardous materials policy-making proce...

The Global Food System as a Transport Pathway for Hazardous Chemicals: The Missing Link between Emissions and Exposure

PubMed Central

Ng, Carla A.; von Goetz, Natalie

2016-01-01

Background: Food is a major pathway for human exposure to hazardous chemicals. The modern food system is becoming increasingly complex and globalized, but models for food-borne exposure typically assume locally derived diets or use concentrations directly measured in foods without accounting for food origin. Such approaches may not reflect actual chemical intakes because concentrations depend on food origin, and representative analysis is seldom available. Processing, packaging, storage, and transportation also impart different chemicals to food and are not yet adequately addressed. Thus, the link between environmental emissions and realistic human exposure is effectively broken. Objectives: We discuss the need for a fully integrated treatment of the modern industrialized food system, and we propose strategies for using existing models and relevant supporting data sources to track chemicals during production, processing, packaging, storage, and transport. Discussion: Fate and bioaccumulation models describe how chemicals distribute in the environment and accumulate through local food webs. Human exposure models can use concentrations in food to determine body burdens based on individual or population characteristics. New models now include the impacts of processing and packaging but are far from comprehensive. We propose to close the gap between emissions and exposure by utilizing a wider variety of models and data sources, including global food trade data, processing, and packaging models. Conclusions: A comprehensive approach that takes into account the complexity of the modern global food system is essential to enable better prediction of human exposure to chemicals in food, sound risk assessments, and more focused risk abatement strategies. Citation: Ng CA, von Goetz N. 2017. The global food system as a transport pathway for hazardous chemicals: the missing link between emissions and exposure. Environ Health Perspect 125:1–7; http://dx.doi.org/10.1289/EHP168 PMID:27384039

Traffic-Related Air Pollution and All-Cause Mortality during Tuberculosis Treatment in California.

PubMed

Blount, Robert J; Pascopella, Lisa; Catanzaro, Donald G; Barry, Pennan M; English, Paul B; Segal, Mark R; Flood, Jennifer; Meltzer, Dan; Jones, Brenda; Balmes, John; Nahid, Payam

2017-09-29

Ambient air pollution and tuberculosis (TB) have an impact on public health worldwide, yet associations between the two remain uncertain. We determined the impact of residential traffic on mortality during treatment of active TB. From 2000-2012, we enrolled 32,875 patients in California with active TB and followed them throughout treatment. We obtained patient data from the California Tuberculosis Registry and calculated traffic volumes and traffic densities in 100- to 400-m radius buffers around residential addresses. We used Cox models to determine mortality hazard ratios, controlling for demographic, socioeconomic, and clinical potential confounders. We categorized traffic exposures as quintiles and determined trends using Wald tests. Participants contributed 22,576 person-years at risk. There were 2,305 deaths during treatment for a crude mortality rate of 1,021 deaths per 10,000 person-years. Traffic volumes and traffic densities in all buffers around patient residences were associated with increased mortality during TB treatment, although the findings were not statistically significant in all buffers. As the buffer size decreased, fifth-quintile mortality hazards increased, and trends across quintiles of traffic exposure became more statistically significant. Increasing quintiles of nearest-road traffic volumes in the 100-m buffer were associated with 3%, 14%, 19%, and 28% increased risk of death during TB treatment [first quintile, referent; second quintile hazard ratio (HR)=1.03 [95% confidence interval (CI): 0.86, 1.25]; third quintile HR=1.14 (95% CI: 0.95, 1.37); fourth quintile HR=1.19 (95% CI: 0.99, 1.43); fifth quintile HR=1.28 (95% CI: 1.07, 1.53), respectively; p-trend=0.002]. Residential proximity to road traffic volumes and traffic density were associated with increased all-cause mortality in patients undergoing treatment for active tuberculosis even after adjusting for multiple demographic, socioeconomic, and clinical factors, suggesting that TB patients are susceptible to the adverse health effects of traffic-related air pollution. https://doi.org/10.1289/EHP1699.

Associations between Personal Care Product Use Patterns and Breast Cancer Risk among White and Black Women in the Sister Study.

PubMed

Taylor, Kyla W; Troester, Melissa A; Herring, Amy H; Engel, Lawrence S; Nichols, Hazel B; Sandler, Dale P; Baird, Donna D

2018-02-21

Many personal care products include chemicals that might act as endocrine disruptors and thus increase the risk of breast cancer. We examined the association between usage patterns of beauty, hair, and skin-related personal care products and breast cancer incidence in the Sister Study, a national prospective cohort study (enrollment 2003-2009). Non-Hispanic black (4,452) and white women (n=42,453) were examined separately using latent class analysis (LCA) to identify groups of individuals with similar patterns of self-reported product use in three categories (beauty, skin, hair). Multivariable Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for associations between product use and breast cancer incidence. A total of 2,326 women developed breast cancer during follow-up (average follow-up=5.4y). Among black women, none of the latent class hazard ratios was elevated, but there were <100 cases in any category, limiting power. Among white women, those classified as "moderate" and "frequent" users of beauty products had increased risk of breast cancer relative to "infrequent" users [HR=1.13 (95% CI: 1.00, 1.27) and HR=1.15 (95% CI: 1.02, 1.30), respectively]. Frequent users of skincare products also had increased risk of breast cancer relative to infrequent users [HR=1.13 (95% CI: 1.00, 1.29)]. None of the hair product classes was associated with increased breast cancer risk. The associations with beauty and skin products were stronger in postmenopausal women than in premenopausal women, but not significantly so. This work generates novel hypotheses about personal care product use and breast cancer risk. Whether these results are due to specific chemicals or to other correlated behaviors needs to be evaluated. https://doi.org/10.1289/EHP1480.

A Unified Probabilistic Framework for Dose–Response Assessment of Human Health Effects

PubMed Central

Slob, Wout

2015-01-01

Background When chemical health hazards have been identified, probabilistic dose–response assessment (“hazard characterization”) quantifies uncertainty and/or variability in toxicity as a function of human exposure. Existing probabilistic approaches differ for different types of endpoints or modes-of-action, lacking a unifying framework. Objectives We developed a unified framework for probabilistic dose–response assessment. Methods We established a framework based on four principles: a) individual and population dose responses are distinct; b) dose–response relationships for all (including quantal) endpoints can be recast as relating to an underlying continuous measure of response at the individual level; c) for effects relevant to humans, “effect metrics” can be specified to define “toxicologically equivalent” sizes for this underlying individual response; and d) dose–response assessment requires making adjustments and accounting for uncertainty and variability. We then derived a step-by-step probabilistic approach for dose–response assessment of animal toxicology data similar to how nonprobabilistic reference doses are derived, illustrating the approach with example non-cancer and cancer datasets. Results Probabilistically derived exposure limits are based on estimating a “target human dose” (HDMI), which requires risk management–informed choices for the magnitude (M) of individual effect being protected against, the remaining incidence (I) of individuals with effects ≥ M in the population, and the percent confidence. In the example datasets, probabilistically derived 90% confidence intervals for HDMI values span a 40- to 60-fold range, where I = 1% of the population experiences ≥ M = 1%–10% effect sizes. Conclusions Although some implementation challenges remain, this unified probabilistic framework can provide substantially more complete and transparent characterization of chemical hazards and support better-informed risk management decisions. Citation Chiu WA, Slob W. 2015. A unified probabilistic framework for dose–response assessment of human health effects. Environ Health Perspect 123:1241–1254; http://dx.doi.org/10.1289/ehp.1409385 PMID:26006063

76 FR 6594 - North Carolina: Final Authorization of State Hazardous Waste Management Program Revisions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-07

... Carolina: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental... authorization of the changes to its hazardous waste program under the Resource Conservation and Recovery Act... Section, RCRA Programs and Materials Management Branch, RCRA Division, U.S. Environmental Protection...

77 FR 60919 - Tennessee: Final Authorization of State Hazardous Waste Management Program Revisions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-05

...: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental..., Division of Solid Waste Management, 5th Floor, L & C Tower, 401 Church Street, Nashville, Tennessee 37243... RCRA hazardous waste management program. We granted authorization for changes to Tennessee's program on...

40 CFR 272.2501 - Wisconsin State-administered program; final authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Wisconsin § 272.2501... cited in this paragraph are incorporated by reference as part of the hazardous waste management program... Applicable to the Hazardous Waste Management Program, (dated August 9, 1993). (2) EPA Approved Wisconsin...

The evolution of a health hazard assessment database management system for military weapons, equipment, and materiel.

PubMed

Murnyak, George R; Spencer, Clark O; Chaney, Ann E; Roberts, Welford C

2002-04-01

During the 1970s, the Army health hazard assessment (HHA) process developed as a medical program to minimize hazards in military materiel during the development process. The HHA Program characterizes health hazards that soldiers and civilians may encounter as they interact with military weapons and equipment. Thus, it is a resource for medical planners and advisors to use that can identify and estimate potential hazards that soldiers may encounter as they train and conduct missions. The U.S. Army Center for Health Promotion and Preventive Medicine administers the program, which is integrated with the Army's Manpower and Personnel Integration program. As the HHA Program has matured, an electronic database has been developed to record and monitor the health hazards associated with military equipment and systems. The current database tracks the results of HHAs and provides reporting designed to assist the HHA Program manager in daily activities.

40 CFR 272.151 - Arizona State-administered program: Final authorization.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Arizona § 272.151... the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) EPA Approved Arizona Statutory Requirements Applicable to the Hazardous Waste Management Program, June 1995...

40 CFR 272.151 - Arizona State-administered program: Final authorization.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Arizona § 272.151... the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) EPA Approved Arizona Statutory Requirements Applicable to the Hazardous Waste Management Program, June 1995...

40 CFR 272.1301 - State-administered program; Final authorization.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Missouri § 272.1301 State... incorporated by reference as part of the hazardous waste management program under subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) Missouri Statutory Requirements Applicable to the Hazardous Waste Management Program...

40 CFR 272.1301 - State-administered program; Final authorization.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Missouri § 272.1301 State... incorporated by reference as part of the hazardous waste management program under subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) Missouri Statutory Requirements Applicable to the Hazardous Waste Management Program...

40 CFR 272.1301 - State-administered program; Final authorization.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Missouri § 272.1301 State... incorporated by reference as part of the hazardous waste management program under subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) Missouri Statutory Requirements Applicable to the Hazardous Waste Management Program...

40 CFR 272.151 - Arizona State-administered program: Final authorization.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Arizona § 272.151... the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) EPA Approved Arizona Statutory Requirements Applicable to the Hazardous Waste Management Program, June 1995...

40 CFR 272.751 - Indiana state-administered program: Final authorization.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Indiana § 272.751... the hazardous waste management program under subtitle C of RCRA, 42 U.S.C. 6921 et seq. This... Applicable to the Hazardous Waste Management Program, dated March 2001. (ii) The EPA approved Indiana...

40 CFR 272.751 - Indiana state-administered program: Final authorization.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Indiana § 272.751... the hazardous waste management program under subtitle C of RCRA, 42 U.S.C. 6921 et seq. This... Applicable to the Hazardous Waste Management Program, dated March 2001. (ii) The EPA approved Indiana...

40 CFR 272.501 - Florida State-administered program: Final authorization.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Florida § 272.501... part of the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) EPA Approved Florida's Statutory Requirements Applicable to the Hazardous Waste Management Program, dated...

40 CFR 272.1301 - State-administered program; Final authorization.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Missouri § 272.1301 State... incorporated by reference as part of the hazardous waste management program under subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) Missouri Statutory Requirements Applicable to the Hazardous Waste Management Program...

40 CFR 272.151 - Arizona State-administered program: Final authorization.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Arizona § 272.151... the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) EPA Approved Arizona Statutory Requirements Applicable to the Hazardous Waste Management Program, June 1995...

40 CFR 272.501 - Florida State-administered program: Final authorization.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Florida § 272.501... part of the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) EPA Approved Florida's Statutory Requirements Applicable to the Hazardous Waste Management Program, dated...

40 CFR 272.501 - Florida State-administered program: Final authorization.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Florida § 272.501... part of the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) EPA Approved Florida's Statutory Requirements Applicable to the Hazardous Waste Management Program, dated...

40 CFR 272.751 - Indiana state-administered program: Final authorization.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Indiana § 272.751... the hazardous waste management program under subtitle C of RCRA, 42 U.S.C. 6921 et seq. This... Applicable to the Hazardous Waste Management Program, dated March 2001. (ii) The EPA approved Indiana...

40 CFR 272.501 - Florida State-administered program: Final authorization.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Florida § 272.501... part of the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) EPA Approved Florida's Statutory Requirements Applicable to the Hazardous Waste Management Program, dated...

40 CFR 272.501 - Florida State-administered program: Final authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Florida § 272.501... part of the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) EPA Approved Florida's Statutory Requirements Applicable to the Hazardous Waste Management Program, dated...

40 CFR 272.1301 - State-administered program; Final authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Missouri § 272.1301 State... incorporated by reference as part of the hazardous waste management program under subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) Missouri Statutory Requirements Applicable to the Hazardous Waste Management Program...

40 CFR 272.151 - Arizona State-administered program: Final authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Arizona § 272.151... the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i) EPA Approved Arizona Statutory Requirements Applicable to the Hazardous Waste Management Program, June 1995...

40 CFR 272.1801 - State-administered program: Final authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Ohio § 272.1801 State... regulations are incorporated by reference and codified as part of the hazardous waste management program under..., 1989, is codified as part of the authorized hazardous waste management program under Subtitle C of RCRA...

40 CFR 272.1201 - Minnesota State-administered program; Final authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Minnesota § 272.1201... incorporated by reference as part of the hazardous waste management program under subtitle C of RCRA, 42 U.S.C... the Hazardous Waste Management Program, dated April 5, 1994. (2) The following statutes and...

76 FR 6564 - Florida: Final Authorization of State Hazardous Waste Management Program Revisions

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-07

...: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental... implement the RCRA hazardous waste management program. We granted authorization for changes to their program..., 06/ 62-730.185(1) F.A.C. Universal Waste Management. 29/07. State Initiated Changes to the 62-730.210...

40 CFR 272.1151 - State-administered program: Final authorization.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Michigan § 272.1151 State... hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. This incorporation, by... part of the authorized hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et...

40 CFR 272.651 - Idaho State-Administered Program: Final Authorization.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Idaho § 272.651 Idaho... hazardous waste management program. However, the EPA retains the authority to exercise its inspection and... incorporated by reference as part of the hazardous waste management program under subtitle C of RCRA, 42 U.S.C...

40 CFR 272.1151 - State-administered program: Final authorization.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Michigan § 272.1151 State... hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. This incorporation, by... part of the authorized hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et...

40 CFR 272.651 - Idaho State-Administered Program: Final Authorization.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Idaho § 272.651 Idaho... hazardous waste management program. However, the EPA retains the authority to exercise its inspection and... incorporated by reference as part of the hazardous waste management program under subtitle C of RCRA, 42 U.S.C...

40 CFR 272.1151 - State-administered program: Final authorization.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Michigan § 272.1151 State... hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. This incorporation, by... part of the authorized hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et...

40 CFR 68.50 - Hazard review.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 2 Prevention Program § 68.50 Hazard review. (a) The owner or operator shall conduct a review of the hazards associated with the regulated substances, process, and...

40 CFR 25.2 - Scope.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Hazardous Waste Program; the NPDES Permit Program; the Dredge and Fill Permit Program; and the Underground... programs. The requirements for public participation in State Hazardous Waste Programs, Dredge and Fill...

40 CFR 25.2 - Scope.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Hazardous Waste Program; the NPDES Permit Program; the Dredge and Fill Permit Program; and the Underground... programs. The requirements for public participation in State Hazardous Waste Programs, Dredge and Fill...

77 FR 65351 - Missouri: Authorization of State Hazardous Waste Management Program Revisions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-26

...: Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental Protection Agency (EPA... Jackson-Johnson, Environmental Protection Agency, Waste Enforcement & Materials Management Branch, 11201... its hazardous waste program under the Resource Conservation and Recovery Act (RCRA). EPA proposes to...

Dioxins and Cardiovascular Mortality: A Review (EHP)

EPA Science Inventory

In spite of its large public health burden, the risk factors for cardiovascular disease remain incompletely understood. Here we review the association of cardiovascular disease (CVD) mortality with exposure to dioxin, a pollutant resulting from the production and combustion of ch...

40 CFR 68.50 - Hazard review.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 16 2014-07-01 2014-07-01 false Hazard review. 68.50 Section 68.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 2 Prevention Program § 68.50 Hazard review. (a) The owner or...

40 CFR 68.50 - Hazard review.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 16 2013-07-01 2013-07-01 false Hazard review. 68.50 Section 68.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 2 Prevention Program § 68.50 Hazard review. (a) The owner or...

40 CFR 68.50 - Hazard review.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 15 2011-07-01 2011-07-01 false Hazard review. 68.50 Section 68.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 2 Prevention Program § 68.50 Hazard review. (a) The owner or...

40 CFR 68.50 - Hazard review.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 16 2012-07-01 2012-07-01 false Hazard review. 68.50 Section 68.50 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 2 Prevention Program § 68.50 Hazard review. (a) The owner or...

75 FR 58423 - Notice of Funding Availability for HUD's Fiscal Year (FY) 2010 Lead-Based Paint Hazard Control...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-24

... Availability for HUD's Fiscal Year (FY) 2010 Lead-Based Paint Hazard Control Grant Program and Lead Hazard Reduction Demonstration Grant Program; Technical Correction AGENCY: Office of Healthy Homes and Lead Hazard...://www.Grants.gov its Notice of Funding Availability (NOFA) for HUD's FY2010 Lead-Based Paint Hazard...

75 FR 24732 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-05

...; Hazard Mitigation Grant Program Application and Reporting AGENCY: Federal Emergency Management [email protected] . SUPPLEMENTARY INFORMATION: Collection of Information Title: Hazard Mitigation Grant... Titles and Numbers: No Form. Abstract: The Hazard Mitigation Grant Program is a post-disaster program...

75 FR 15613 - Hazardous Materials Transportation; Registration and Fee Assessment Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-30

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part 107 [Docket No. PHMSA-2009-0201 (HM-208H)] RIN 2137-AE47 Hazardous Materials Transportation... registration program are to gather information about the transportation of hazardous materials, and to fund the...

78 FR 70225 - West Virginia: Final Authorization of State Hazardous Waste Management Program Revisions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-25

... Department of Environmental Protection, (WVDEP), Division of Water and Waste Management, 601 57th Street SE...] West Virginia: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY... for final authorization of revisions to its hazardous waste program under the Resource Conservation...

75 FR 40846 - Agency Information Collection Activities: Submission for OMB Review; Comment Request, OMB No...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-14

...; State Administrative Plan for the Hazard Mitigation Grant Program AGENCY: Federal Emergency Management...: Collection of Information Title: State Administrative Plan for the Hazard Mitigation Grant Program. Type of... guide that details how the State will administer the Hazard Mitigation Grant Program (HMGP). An approved...

78 FR 15299 - New York: Final Authorization of State Hazardous Waste Management Program Revision

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-11

... authorization of changes to its hazardous waste program under the Solid Waste Disposal Act, as amended, commonly... Solid Waste Amendments of 1984 (HSWA). New Federal requirements and prohibitions imposed by Federal...: Final Authorization of State Hazardous Waste Management Program Revision AGENCY: Environmental...

75 FR 81187 - South Dakota: Final Authorization of State Hazardous Waste Management Program Revision

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-27

...: Final Authorization of State Hazardous Waste Management Program Revision AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed Rule. SUMMARY: The Solid Waste Disposal Act, as amended, commonly... Agency (EPA) to authorize states to operate their hazardous waste management programs in lieu of the...

Hazardous waste management programs; Florida: authorization for interim authorization phase I--Environmental Protection Agency. Notice of final determination.

PubMed

1982-05-07

The State of Florida has applied for interim Authorization Phase I. EPA has reviewed Florida's application for Phase I and has determined that Florida's hazardous waste program is substantially equivalent to the Federal program covered by Phase I. The State of Florida is, hereby, granted Interim Authorization for Phase I to operate the State 's hazardous waste program, in lieu of the Federal program.

A New Master of Natural Hazards Program at The Australian National University

NASA Astrophysics Data System (ADS)

Pozgay, S.; Zoleta-Nantes, D.

2009-12-01

The new Master of Natural Hazards program at The Australian National University provides a multi-disciplinary approach to the study and monitoring of geophysical processes that can lead to the recognition of hazards and a consequent reduction of their impacts through emergency measures, disaster plans, and relief and rehabilitation. The program provides people with an understanding of the most up-to-date scientific understanding on the causes of natural hazards, their effects on human societies, and ways to mitigate their impacts and reduce their losses by focusing on Australia and the Asia-Pacific case studies. The Master of Natural Hazards program brings together the expertise of researchers across the university to provide an opportunity for students to do coursework and research projects that will provide them with extensive knowledge of the natural hazards that occur and pose the greatest risks on human communities in the Asia-Pacific, and an understanding of the human dimensions of the natural hazards occurrences. The program consists of two compulsory courses each in the Earth Sciences and in the Social Sciences that are designed to provide a complementary and comprehensive overview of natural hazards issues. Elective courses can be of a general grouping, or students may choose one of four Focus Streams: Environmental and Geographic Studies; Climate Change; Earth Structure and Imaging; or Socio-economic, Development and Policy Studies. A special case study project will involve writing a thesis on a topic to be approved by the Program Conveners and will comprise a body of work on an approved topic in natural hazards in the Asia-Pacific region. Students in this program will gain a broad scientific knowledge and methodological skills to understand the physical causes and frequency of the most important natural hazards in the Asia-Pacific region, as well as the latest scientific methods and best practices of monitoring them for hazard mapping and disaster reduction purposes. Furthermore, students will learn to apply critical thinking in studying the involvement of societies’ social systems in framing and influencing the severity of impacts and destructions that are brought about by different physical events. The academic training in hazards and disaster research that the program offers will enable students to get actively involved in the preparation of short- and long-term disaster mitigation programs that can help members of communities in Australia and the Asia-Pacific region who, without sufficient knowledge on hazards and skills on disaster management, would be left vulnerable against the adversities that can be brought about by natural hazards.

Relative roles of aerosols, SST, and snow impurity on snowmelt over the Tibetan Plateau and its their impacts on South Asian summer monsoon

NASA Astrophysics Data System (ADS)

Kim, K. M.; Tsay, S. C.; Lau, W. K. M.; Yasunari, T. J.; Mahanama, S. P. P.; Koster, R. D.; daSilva, A.

2017-12-01

We examine the relative roles of atmospheric aerosol radiative forcing, year-to-year SST (sea surface temperature) variability, and surface radiative forcing by snow impurity on snowmelt over the Tibetan Plateau and their impacts on rainfall and circulation of South Asian summer monsoon. Five-member ensemble experiments are conducted with NASA's GEOS-5 (Goddard Earth Observing System model version 5), equipped with a snow darkening module - GOSWIM (GOddard SnoW Impurity Module), on the Water-Year 2008 (October 2007 to September 2008). Asian summer monsoon in 2008 was near normal in terms of monsoon rainfall over India subcontinent. However, rainfall was excessive in the North while the southern India suffered from the rainfall deficit. The 2008 summer monsoon was accompanied with high loading of aerosols in the Arabian Sea and La Niña condition in the tropical Pacific. To examine the roles high aerosol loading and La Niña condition on the north-south dipole in Indian monsoon rainfall, two sets of experiments, in addition to control runs (CNTRL), are conducted without SST anomalies (CSST) and aerosol radiative feedback (NRF), respectively. Results show that increased aerosol loading in early summer is associated with the increased dust transport during La Niña years. Increased aerosols over the northern India induces EHP-like (elevated heat pump) circulation and increases rainfall over the India subcontinent. Aerosol radiative forcing feedback (CNTRL-NRF) strengthens the EHP-like monsoon circulation even more. Results indicate that anomalous circulation associated with La Niña condition increases aerosol loading by enhancing dust transport as well as by increasing aerosol lifetime. Increased aerosols induces EHP-like feedback processes and increases rainfall over the India subcontinent.

A continuing high incidence of subacute sclerosing panencephalitis (SSPE) in the Eastern Highlands of Papua New Guinea.

PubMed Central

Takasu, T.; Mgone, J. M.; Mgone, C. S.; Miki, K.; Komase, K.; Namae, H.; Saito, Y.; Kokubun, Y.; Nishimura, T.; Kawanishi, R.; Mizutani, T.; Markus, T. J.; Kono, J.; Asuo, P. G.; Alpers, M. P.

2003-01-01

The aims of this descriptive study were to confirm the high incidence of subacute sclerosing panencephalitis (SSPE) previously reported from Papua New Guinea (PNG) and to relate SSPE to previous measles vaccination and measles illness. From February 1997 to April 1999 we diagnosed a total of 55 patients with SSPE at Goroka Base General Hospital in Eastern Highlands Province (EHP) of PNG. The diagnosis was based on high cerebrospinal fluid and serum measles virus antibody titres with progressive neurological disorder and myoclonic jerks. Of these 55 patients 42 were from EHP, including 32 whose onset was in the 2-year period 1997-1998. The annual incidence of SSPE in EHP in these 2 years was 98 per million population under 20 years of age, the highest ever reported. This incidence was more than ten times higher than the highest incidence in the prevaccine era reported from elsewhere. The mean age of onset of SSPE was 7.7 years (range 2.8-14.8 years) and the interval between measles and the onset of SSPE, where known, had a mean of 5.9 years and a range of 2.5-11.1 years. Among the SSPE patients 19 had a documented history of measles vaccination. Eight of these 19 also had documentation of previous measles illness; of these, seven were vaccinated after the development of measles and one was vaccinated 20 days before measles illness. Two non-SSPE children received vaccination twice which was documented and subsequently developed measles which was also substantiated by documentation. Two patients with SSPE yielded amplified nucleotide sequences of measles virus that were different from any of the vaccine strains. We found no evidence to implicate measles vaccination in the development of SSPE. PMID:14596530

40 CFR 265.1 - Purpose, scope, and applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., stores, or disposes of hazardous waste in a State with a RCRA hazardous waste program authorized under... apply: (i) If the authorized State RCRA program does not cover disposal of hazardous waste by means of... them out include all Federal program requirements identified in § 271.1(j); (5) The owner or operator...

HAZ-ED Classroom Activities for Understanding Hazardous Waste.

ERIC Educational Resources Information Center

Environmental Protection Agency, Washington, DC.

The Federal Superfund Program investigates and cleans up hazardous waste sites throughout the United States. Part of this program is devoted to informing the public and involving people in the process of cleaning up hazardous waste sites from beginning to end. The Haz-Ed program was developed to assist the Environmental Protection Agency's (EPA)…

75 FR 8239 - School Food Safety Program Based on Hazard Analysis and Critical Control Point Principles (HACCP...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-24

... 0584-AD65 School Food Safety Program Based on Hazard Analysis and Critical Control Point Principles... Safety Program Based on Hazard Analysis and Critical Control Point Principles (HACCP) was published on... of Management and Budget (OMB) cleared the associated information collection requirements (ICR) on...

40 CFR 272.701 - State-administered program: Final authorization.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Illinois § 272.701 State... Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51 as part of the hazardous waste management... Administrator on January 26, 1990, is part of the authorized hazardous waste management program under Subtitle C...

40 CFR 272.701 - State-administered program: Final authorization.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Illinois § 272.701 State... Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51 as part of the hazardous waste management... Administrator on January 26, 1990, is part of the authorized hazardous waste management program under Subtitle C...

40 CFR 272.651 - Idaho State-Administered Program: Final Authorization.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Idaho § 272.651 Idaho..., 2008. (b) The State of Idaho has primary responsibility for enforcing its hazardous waste management... part of the hazardous waste management program under subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i...

40 CFR 272.701 - State-administered program: Final authorization.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Illinois § 272.701 State... Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51 as part of the hazardous waste management... Administrator on January 26, 1990, is part of the authorized hazardous waste management program under Subtitle C...

40 CFR 272.651 - Idaho State-Administered Program: Final Authorization.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Idaho § 272.651 Idaho..., 2008. (b) The State of Idaho has primary responsibility for enforcing its hazardous waste management... part of the hazardous waste management program under subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i...

40 CFR 272.701 - State-administered program: Final authorization.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Illinois § 272.701 State... Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51 as part of the hazardous waste management... Administrator on January 26, 1990, is part of the authorized hazardous waste management program under Subtitle C...

78 FR 15338 - New York: Final Authorization of State Hazardous Waste Management Program Revisions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-11

... authorization of changes to its hazardous waste program under the Solid Waste Disposal Act, as amended, commonly... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 271 [EPA-R02-RCRA-2013-0144; FRL-9693-3] New York: Final Authorization of State Hazardous Waste Management Program Revisions AGENCY: Environmental...

40 CFR 272.701 - State-administered program: Final authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Illinois § 272.701 State... Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51 as part of the hazardous waste management... Administrator on January 26, 1990, is part of the authorized hazardous waste management program under Subtitle C...

40 CFR 272.651 - Idaho State-Administered Program: Final Authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Idaho § 272.651 Idaho..., 2008. (b) The State of Idaho has primary responsibility for enforcing its hazardous waste management... part of the hazardous waste management program under subtitle C of RCRA, 42 U.S.C. 6921 et seq. (i...

Association between Exposure to p,p′-DDT and Its Metabolite p,p′-DDE with Obesity: Integrated Systematic Review and Meta-Analysis

PubMed Central

Cano-Sancho, German; Salmon, Andrew G.

2017-01-01

Background: The prevalence of obesity is increasing in all countries, becoming a substantial public health concern worldwide. Increasing evidence has associated obesity with persistent pollutants such as the pesticide DDT and its metabolite p,p′-DDE. Objectives: Our objective was to systematically review the literature on the association between exposure to the pesticide DDT and its metabolites and obesity to develop hazard identification conclusions. Methods: We applied a systematic review-based strategy to identify and integrate evidence from epidemiological, in vivo, and in vitro studies. The evidence from prospective epidemiological studies was quantitatively synthesized by meta-analysis. We rated the body of evidence and integrated the streams of evidence to systematically develop hazard identification conclusions. Results: We identified seven epidemiological studies reporting prospective associations between exposure to p,p′-DDE and adiposity assessed by body mass index (BMI) z-score. The results from the meta-analysis revealed positive associations between exposure to p,p′-DDE and BMI z-score (β=0.13 BMI z-score (95% CI: 0.01, 0.25) per log increase of p,p′-DDE). Two studies constituted the primary in vivo evidence. Both studies reported positive associations between exposure to p,p′-DDT and increased adiposity in rodents. We identified 19 in vivo studies and 7 in vitro studies that supported the biological plausibility of the obesogenic effects of p,p′-DDT and p,p′-DDE. Conclusions: We classified p,p′-DDT and p,p′-DDE as “presumed” to be obesogenic for humans, based on a moderate level of primary human evidence, a moderate level of primary in vivo evidence, and a moderate level of supporting evidence from in vivo and in vitro studies. https://doi.org/10.1289/EHP527 PMID:28934091

Projecting Age-Stratified Risk of Exposure to Inland Flooding and Wildfire Smoke in the United States under Two Climate Scenarios.

PubMed

Mills, David; Jones, Russell; Wobus, Cameron; Ekstrom, Julia; Jantarasami, Lesley; St Juliana, Alexis; Crimmins, Allison

2018-04-17

The public health community readily recognizes flooding and wildfires as climate-related health hazards, but few studies quantify changes in risk of exposure, particularly for vulnerable children and older adults. This study quantifies future populations potentially exposed to inland flooding and wildfire smoke under two climate scenarios, highlighting the populations in particularly vulnerable age groups (≤4 y old and ≥65 y old). Spatially explicit projections of inland flooding and wildfire under two representative concentration pathways (RCP8.5 and RCP4.5) are integrated with static (2010) and dynamic (2050 and 2090) age-stratified projections of future contiguous U.S. populations at the county level. In both 2050 and 2090, an additional one-third of the population will live in areas affected by larger and more frequent inland flooding under RCP8.5 than under RCP4.5. Approximately 15 million children and 25 million older adults could avoid this increased risk of flood exposure each year by 2090 under a moderate mitigation scenario (RCP4.5 compared with RCP8.5). We also find reduced exposure to wildfire smoke under the moderate mitigation scenario. Nearly 1 million young children and 1.7 million older adults would avoid exposure to wildfire smoke each year under RCP4.5 than under RCP8.5 by the end of the century. By integrating climate-driven hazard and population projections, newly created county-level exposure maps identify locations of potential significant future public health risk. These potential exposure results can help inform actions to prevent and prepare for associated future adverse health outcomes, particularly for vulnerable children and older adults. https://doi.org/10.1289/EHP2594.

Effects of Radon and UV Exposure on Skin Cancer Mortality in Switzerland.

PubMed

Vienneau, Danielle; de Hoogh, Kees; Hauri, Dimitri; Vicedo-Cabrera, Ana M; Schindler, Christian; Huss, Anke; Röösli, Martin

2017-06-16

Skin cancer incidence in Switzerland is among the highest in the world. In addition to exposure to ultraviolet (UV) radiation, radon alpha particles attached to aerosols can adhere to the skin and potentially cause carcinogenic effects. We investigated the effects of radon and UV exposure on skin cancer mortality. Cox proportional hazard regression was used to study the association between exposures and skin cancer mortality in adults from the Swiss National Cohort. Modeled radon exposure and erythemal-weighted UV dose were assigned to addresses at baseline. Effect estimates were adjusted for sex, civil status, mother tongue, education, job position, neighborhood socioeconomic position, and UV exposure from outdoor occupation. The study included 5.2 million adults (mean age 48 y) and 2,989 skin cancer deaths, with 1,900 indicating malignant melanoma (MM) as the primary cause of death. Adjusted hazard ratios (HR) for MM at age 60 were 1.16 (95% CI: 1.04, 1.29) per 100 Bq/m 3 radon and 1.11 (1.01, 1.23) per W/m 2 in UV dose. Radon effects decreased with age. Risk of MM death associated with residential UV exposure was higher for individuals engaged in outdoor work with UV exposure (HR 1.94 [1.17, 3.23]), though not statistically significantly different compared to not working outdoors (HR 1.09 [0.99, 1.21], p =0.09). There is considerable variation in radon and UV exposure across Switzerland. Our study suggests both are relevant risk factors for skin cancer mortality. A better understanding of the role of the UV radiation and radon exposure is of high public health relevance. https://doi.org/10.1289/EHP825.

Association between Exposure to p,p'-DDT and Its Metabolite p,p'-DDE with Obesity: Integrated Systematic Review and Meta-Analysis.

PubMed

Cano-Sancho, German; Salmon, Andrew G; La Merrill, Michele A

2017-09-18

The prevalence of obesity is increasing in all countries, becoming a substantial public health concern worldwide. Increasing evidence has associated obesity with persistent pollutants such as the pesticide DDT and its metabolite p,p '-DDE. Our objective was to systematically review the literature on the association between exposure to the pesticide DDT and its metabolites and obesity to develop hazard identification conclusions. We applied a systematic review-based strategy to identify and integrate evidence from epidemiological, in vivo , and in vitro studies. The evidence from prospective epidemiological studies was quantitatively synthesized by meta-analysis. We rated the body of evidence and integrated the streams of evidence to systematically develop hazard identification conclusions. We identified seven epidemiological studies reporting prospective associations between exposure to p,p' -DDE and adiposity assessed by body mass index (BMI) z -score. The results from the meta-analysis revealed positive associations between exposure to p,p' -DDE and BMI z -score (β=0.13 BMI z -score (95% CI: 0.01, 0.25) per log increase of p,p' -DDE). Two studies constituted the primary in vivo evidence. Both studies reported positive associations between exposure to p,p' -DDT and increased adiposity in rodents. We identified 19 in vivo studies and 7 in vitro studies that supported the biological plausibility of the obesogenic effects of p,p' -DDT and p,p' -DDE. We classified p,p' -DDT and p,p' -DDE as "presumed" to be obesogenic for humans, based on a moderate level of primary human evidence, a moderate level of primary in vivo evidence, and a moderate level of supporting evidence from in vivo and in vitro studies. https://doi.org/10.1289/EHP527.

Effects of Radon and UV Exposure on Skin Cancer Mortality in Switzerland

PubMed Central

de Hoogh, Kees; Hauri, Dimitri; Vicedo-Cabrera, Ana M.; Schindler, Christian; Huss, Anke; Röösli, Martin

2017-01-01

Background: Skin cancer incidence in Switzerland is among the highest in the world. In addition to exposure to ultraviolet (UV) radiation, radon alpha particles attached to aerosols can adhere to the skin and potentially cause carcinogenic effects. Objectives: We investigated the effects of radon and UV exposure on skin cancer mortality. Methods: Cox proportional hazard regression was used to study the association between exposures and skin cancer mortality in adults from the Swiss National Cohort. Modeled radon exposure and erythemal-weighted UV dose were assigned to addresses at baseline. Effect estimates were adjusted for sex, civil status, mother tongue, education, job position, neighborhood socioeconomic position, and UV exposure from outdoor occupation. Results: The study included 5.2 million adults (mean age 48 y) and 2,989 skin cancer deaths, with 1,900 indicating malignant melanoma (MM) as the primary cause of death. Adjusted hazard ratios (HR) for MM at age 60 were 1.16 (95% CI: 1.04, 1.29) per 100Bq/m3 radon and 1.11 (1.01, 1.23) per W/m2 in UV dose. Radon effects decreased with age. Risk of MM death associated with residential UV exposure was higher for individuals engaged in outdoor work with UV exposure (HR 1.94 [1.17, 3.23]), though not statistically significantly different compared to not working outdoors (HR 1.09 [0.99, 1.21], p=0.09). Conclusions: There is considerable variation in radon and UV exposure across Switzerland. Our study suggests both are relevant risk factors for skin cancer mortality. A better understanding of the role of the UV radiation and radon exposure is of high public health relevance. https://doi.org/10.1289/EHP825 PMID:28686556

Hot off the Press

ERIC Educational Resources Information Center

Hines, Stefani; Tart, Kimberly Thigpen; Hemminger, Laura; Schlegel, Barry; Stephan, Wendy; Pitman, Lisa

2006-01-01

Recently published research can be paired with engaging activities to keep students informed about the rapidly changing world of science. "Environmental Health Perspectives" (EHP), a peer-reviewed environmental health research journal (published by the National Institute of Environmental Health Sciences, part of the National Institutes of Health),…

FY 2017 Hazardous Waste Management Grant Program for Tribes

EPA Pesticide Factsheets

This notice announces the availability of funds and solicits proposals from federally-recognized tribes or intertribal consortia for the development and implementation of hazardous waste programs and for building capacity to address hazardous waste

77 FR 65574 - Notice of Proposed Information Collection: Healthy Homes and Lead Hazard Control Programs Data...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-29

... Information Collection: Healthy Homes and Lead Hazard Control Programs Data Collection--Progress Reporting AGENCY: Office of Healthy Homes and Lead Hazard Control, HUD. ACTION: Notice. SUMMARY: The revised... of Healthy Homes and Lead Hazard Control, Department of Housing and Urban Development, 451 7th Street...

Should non-citizens have access to publicly funded health care?: a study of public attitudes and their affecting factors.

PubMed

Sun, L-Y; Lee, E-W; Zahra, A; Park, J-H

2015-09-01

To analyse public attitudes towards access for non-citizens to publicly funded health care and to assess the factors that affect such attitudes. Cross-sectional study. Data from 29 countries were used for a multilevel regression, and data from four countries (United States, Sweden, Philippines, and Korea) were used for a linear regression. The data were collected from the International Social Survey Program (ISSP), the World Bank, the Organization for Economic Cooperation and Development (OECD), and the United Nations. The dependent variable was considered to be agreement for non-citizen access to publicly funded health care. The independent variables included: the gross national income (GNI), the gross national income coefficient (GINI), sex, age, education, household income, employment, health insurance, self-related health status, chronic illness, percent having insurance, percent having public insurance, percent employed, percent migrants, percent of health expenditure of the total gross domestic product (GDP), and percent of social expenditure of the total GDP. Egalitarianism for education policy (EEP), egalitarianism for health policy (EHP), and willingness to contribute to an egalitarian health policy (WCHP) were also examined. In the countries surveyed, more than half of the citizens agreed that non-citizens should have access to publicly funded health care. Agreement with that statement had a negative trend with respect to the GNI. The percent having public insurance and WCHP had a significantly positive association with agreement while the percent of those with insurance had a negative relationship. In the USA, household income, EHP, and WCHP were positively associated with agreement, while females were inversely associated with agreement. In Sweden, having health insurance had an inverse association to agreement while females, postsecondary education, health insurance coverage, and WCHP were positively associated with agreement. In the Philippines, household income, EEP, and EHP had significant negative associations with agreement while WCHP had a positive relationship. In Korea, household income and self-rated health status were positively associated with agreement, while postsecondary education had a negative association. Public attitudes towards allowing non-citizens to have access to publicly funded health care present high levels of variation, even among developed countries or countries with similar GDPs. The specific socio-economic conditions within a country and an individual's own social, demographic, and economic background can have different effects on the individual's attitudes towards non-citizens. On a global level, coverage of public health insurance plays an important role for enhancing the public's positive attitudes towards non-citizens' access to publicly funded health care. On a national level, health care policies tailored toward non-citizens based on the specific situation of each country and region are necessary. Copyright © 2015 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

Using hazard maps to identify and eliminate workplace hazards: a union-led health and safety training program.

PubMed

Anderson, Joe; Collins, Michele; Devlin, John; Renner, Paul

2012-01-01

The Institute for Sustainable Work and Environment and the Utility Workers Union of America worked with a professional evaluator to design, implement, and evaluate the results of a union-led system of safety-based hazard identification program that trained workers to use hazard maps to identify workplace hazards and target them for elimination. The evaluation documented program implementation and impact using data collected from both qualitative interviews and an on-line survey from worker trainers, plant managers, and health and safety staff. Managers and workers reported that not only were many dangerous hazards eliminated as a result of hazard mapping, some of which were long-standing, difficult-to-resolve issues, but the evaluation also documented improved communication between union members and management that both workers and managers agreed resulted in better, more sustainable hazard elimination.

FY 2018 Hazardous Waste Management Grant Program For Tribes

EPA Pesticide Factsheets

This notice announces the availability of funds and solicits proposals from federally-recognized tribes or intertribal consortia for the development and implementation of hazardous waste programs and for building capacity to address hazardous waste managem

Simulation program for estimating statistical power of Cox's proportional hazards model assuming no specific distribution for the survival time.

PubMed

Akazawa, K; Nakamura, T; Moriguchi, S; Shimada, M; Nose, Y

1991-07-01

Small sample properties of the maximum partial likelihood estimates for Cox's proportional hazards model depend on the sample size, the true values of regression coefficients, covariate structure, censoring pattern and possibly baseline hazard functions. Therefore, it would be difficult to construct a formula or table to calculate the exact power of a statistical test for the treatment effect in any specific clinical trial. The simulation program, written in SAS/IML, described in this paper uses Monte-Carlo methods to provide estimates of the exact power for Cox's proportional hazards model. For illustrative purposes, the program was applied to real data obtained from a clinical trial performed in Japan. Since the program does not assume any specific function for the baseline hazard, it is, in principle, applicable to any censored survival data as long as they follow Cox's proportional hazards model.

A Program on Hazardous Waste Management.

ERIC Educational Resources Information Center

Kummler, Ralph H.; And Others

1989-01-01

Provides an overview of the "Hazardous Waste Management Graduate Certificate" program at Wayne State University. Describes four required courses and nine optional courses. Discusses the development of a Master program and the curriculum of the Master program. (YP)

A pilot outreach program for small quantity generators of hazardous waste.

PubMed Central

Brown, M S; Kelley, B G; Gutensohn, J

1988-01-01

The Massachusetts Department of Environmental Management initiated a pilot project to improve compliance with hazardous waste regulations and management of hazardous wastes with auto body shops around the state. The program consisted of mass mailings, a series of workshops throughout the state, a coordinated inspection program by the state regulatory agency, and technology transfer. At the start of the program in January 1986, approximately 650 of the estimated 2,350 auto body shops in the state had notified EPA of their waste generating activities; by January 1987, approximately 1,200 shops had done so. Suggestions for improving program efforts include tailoring the outreach effort to the industry, government-sponsored research and development directed at the needs of small firms, mandatory participation in hazardous waste transportation programs, and better coordination by EPA of its information collection and distribution program. PMID:3421393

Ab initio molecular dynamics calculations on scattering of hyperthermal H atoms from Cu(111) and Au(111).

PubMed

Kroes, Geert-Jan; Pavanello, Michele; Blanco-Rey, María; Alducin, Maite; Auerbach, Daniel J

2014-08-07

Energy loss from the translational motion of an atom or molecule impinging on a metal surface to the surface may determine whether the incident particle can trap on the surface, and whether it has enough energy left to react with another molecule present at the surface. Although this is relevant to heterogeneous catalysis, the relative extent to which energy loss of hot atoms takes place to phonons or electron-hole pair (ehp) excitation, and its dependence on the system's parameters, remain largely unknown. We address these questions for two systems that present an extreme case of the mass ratio of the incident atom to the surface atom, i.e., H + Cu(111) and H + Au(111), by presenting adiabatic ab initio molecular dynamics (AIMD) predictions of the energy loss and angular distributions for an incidence energy of 5 eV. The results are compared to the results of AIMDEFp calculations modeling energy loss to ehp excitation using an electronic friction ("EF") model applied to the AIMD trajectories, so that the energy loss to the electrons is calculated "post" ("p") the computation of the AIMD trajectory. The AIMD calculations predict average energy losses of 0.38 eV for Cu(111) and 0.13-0.14 eV for Au(111) for H-atoms that scatter from these surfaces without penetrating the surface. These energies closely correspond with energy losses predicted with Baule models, which is suggestive of structure scattering. The predicted adiabatic integral energy loss spectra (integrated over all final scattering angles) all display a lowest energy peak at an energy corresponding to approximately 80% of the average adiabatic energy loss for non-penetrative scattering. In the adiabatic limit, this suggests a way of determining the approximate average energy loss of non-penetratively scattered H-atoms from the integral energy loss spectrum of all scattered H-atoms. The AIMDEFp calculations predict that in each case the lowest energy loss peak should show additional energy loss in the range 0.2-0.3 eV due to ehp excitation, which should be possible to observe. The average non-adiabatic energy losses for non-penetrative scattering exceed the adiabatic losses to phonons by 0.9-1.0 eV. This suggests that for scattering of hyperthermal H-atoms from coinage metals the dominant energy dissipation channel should be to ehp excitation. These predictions can be tested by experiments that combine techniques for generating H-atom beams that are well resolved in translational energy and for detecting the scattered atoms with high energy-resolution.

Blood Cadmium Levels and Incident Cardiovascular Events during Follow-up in a Population-Based Cohort of Swedish Adults: The Malmö Diet and Cancer Study

PubMed Central

Barregard, Lars; Sallsten, Gerd; Fagerberg, Björn; Borné, Yan; Persson, Margaretha; Hedblad, Bo; Engström, Gunnar

2015-01-01

Background: Cadmium exposure may increase the risk of cardiovascular disease. The only published longitudinal study on cadmium and incident cardiovascular disease was performed in American Indians with relatively high cadmium exposure. Objectives: Our aim was to examine the association between blood cadmium at baseline and incident cardiovascular events in a population-based study of Swedish men and women with cadmium levels similar to those of most European and U.S. populations. Methods: A Swedish population-based cohort (n = 6,103, age 46–67 years) was recruited between 1991 and 1994. After we excluded those with missing data on smoking, 4,819 participants remained. Acute coronary events, other major cardiac events, stroke, and cardiovascular mortality were followed until 2010. Associations with blood cadmium (estimated from cadmium in erythrocytes) were analyzed using Cox proportional hazards regression including potential confounders and important cardiovascular risk factors. Results: Hazard ratios for all cardiovascular end points were consistently increased for participants in the 4th blood cadmium quartile (median, 0.99 μg/L). In models that also included sex, smoking, waist circumference, education, physical activity, alcohol intake, serum triglycerides, HbA1c, and C-reactive protein, the hazard ratios comparing the highest and lowest quartiles of exposure were 1.8 (95% CI: 1.2, 2.7) for acute coronary events, and 1.9 (1.3, 2.9) for stroke. Hazard ratios in never-smokers were consistent with these estimates. Conclusions: Blood cadmium in the highest quartile was associated with incident cardiovascular disease and mortality in our population-based samples of Swedish adults. The consistent results among never-smokers are important because smoking is a strong confounder. Our findings suggest that measures to reduce cadmium exposures are warranted, even in populations without unusual sources of exposure. Citation: Barregard L, Sallsten G, Fagerberg B, Borné Y, Persson M, Hedblad B, Engström G. 2016. Blood cadmium levels and incident cardiovascular events during follow-up in a population-based cohort of Swedish adults: the Malmö Diet and Cancer Study. Environ Health Perspect 124:594–600; http://dx.doi.org/10.1289/ehp.1509735 PMID:26517380

Battery testing at Argonne National Laboratory

NASA Astrophysics Data System (ADS)

Deluca, W. H.; Gillie, K. R.; Kulaga, J. E.; Smaga, J. A.; Tummillo, A. F.; Webster, C. E.

1993-03-01

Argonne National Laboratory's Analysis & Diagnostic Laboratory (ADL) tests advanced batteries under simulated electric and hybrid vehicle operating conditions. The ADL facilities also include a post-test analysis laboratory to determine, in a protected atmosphere if needed, component compositional changes and failure mechanisms. The ADL provides a common basis for battery performance characterization and life evaluations with unbiased application of tests and analyses. The battery evaluations and post-test examinations help identify factors that limit system performance and life and the most-promising R&D approaches for overcoming these limitations. Since 1991, performance characterizations and/or life evaluations have been conducted on eight battery technologies: Na/S, Li/S, Zn/Br, Ni/MH, Ni/Zn, Ni/Cd, Ni/Fe, and lead-acid. These evaluations were performed for the Department of Energy's. Office of Transportation Technologies, Electric and Hybrid Propulsion Division (DOE/OTT/EHP), and Electric Power Research Institute (EPRI) Transportation Program. The results obtained are discussed.

National Earthquake Hazards Reduction Program; time to expand

USGS Publications Warehouse

Steinbrugge, K.V.

1990-01-01

All of us in earthquake engineering, seismology, and many related disciplines have been directly or indirectly affected by the National Earthquake Hazards Reduction Program (NEHRP). This program was the result of the Earthquake Hazards Reduction Act of 1977 (Public Law 95-124). With well over a decade of experience, should this expression of public policy now take a different or expanded role? 

Spaceflight Toxicology

NASA Technical Reports Server (NTRS)

Meyers, Valerie

2008-01-01

This viewgraph presentation provides a review of NASA Johnson Space Center's Toxicology program. The mission of this program is to protect crews from toxic exposures during spaceflight. The presentation reviews some of the health hazards. A toxicological hazard level chart is presented that reviews the rating of hazard level, irritancy, systemic effects and containability. The program also participates in the Lunar Airborne Dust Toxicity Advisory Group.

Screening for Chemical Contributions to Breast Cancer Risk: A Case Study for Chemical Safety Evaluation

PubMed Central

Ackerman, Janet M.; Dairkee, Shanaz H.; Fenton, Suzanne E.; Johnson, Dale; Navarro, Kathleen M.; Osborne, Gwendolyn; Rudel, Ruthann A.; Solomon, Gina M.; Zeise, Lauren; Janssen, Sarah

2015-01-01

Background Current approaches to chemical screening, prioritization, and assessment are being reenvisioned, driven by innovations in chemical safety testing, new chemical regulations, and demand for information on human and environmental impacts of chemicals. To conceptualize these changes through the lens of a prevalent disease, the Breast Cancer and Chemicals Policy project convened an interdisciplinary expert panel to investigate methods for identifying chemicals that may increase breast cancer risk. Methods Based on a review of current evidence, the panel identified key biological processes whose perturbation may alter breast cancer risk. We identified corresponding assays to develop the Hazard Identification Approach for Breast Carcinogens (HIA-BC), a method for detecting chemicals that may raise breast cancer risk. Finally, we conducted a literature-based pilot test of the HIA-BC. Results The HIA-BC identifies assays capable of detecting alterations to biological processes relevant to breast cancer, including cellular and molecular events, tissue changes, and factors that alter susceptibility. In the pilot test of the HIA-BC, chemicals associated with breast cancer all demonstrated genotoxic or endocrine activity, but not necessarily both. Significant data gaps persist. Conclusions This approach could inform the development of toxicity testing that targets mechanisms relevant to breast cancer, providing a basis for identifying safer chemicals. The study identified important end points not currently evaluated by federal testing programs, including altered mammary gland development, Her2 activation, progesterone receptor activity, prolactin effects, and aspects of estrogen receptor β activity. This approach could be extended to identify the biological processes and screening methods relevant for other common diseases. Citation Schwarzman MR, Ackerman JM, Dairkee SH, Fenton SE, Johnson D, Navarro KM, Osborne G, Rudel RA, Solomon GM, Zeise L, Janssen S. 2015. Screening for chemical contributions to breast cancer risk: a case study for chemical safety evaluation. Environ Health Perspect 123:1255–1264; http://dx.doi.org/10.1289/ehp.1408337 PMID:26032647

RMP Guidance for Chemical Distributors - Chapter 7: Prevention Program (Program 3)

EPA Pesticide Factsheets

The OSHA Process Safety Management program has legal authority for on-site consequences, EPA's Prevention Program for offsite consequences, so your process hazard analysis (PHA) team may have to assess new hazards to the public and offsite environment.

Thermal and flame retardant behaviors of cotton fiber treated with phosphoramidate derivatives

USDA-ARS?s Scientific Manuscript database

In this research, two phosphoramidate derivatives EHP Diethyl 3-hydroxypropylphos phoramidate and MHP Dimethyl 3-hydroxypropylphos phoramidate were prepared in very high yield and purity by one step procedure and the cotton fabrics treated with them at different levels of add-on (5 - 20 wt %) were c...

Advancing Alternative Analysis: Integration of Decision Science.

PubMed

Malloy, Timothy F; Zaunbrecher, Virginia M; Batteate, Christina M; Blake, Ann; Carroll, William F; Corbett, Charles J; Hansen, Steffen Foss; Lempert, Robert J; Linkov, Igor; McFadden, Roger; Moran, Kelly D; Olivetti, Elsa; Ostrom, Nancy K; Romero, Michelle; Schoenung, Julie M; Seager, Thomas P; Sinsheimer, Peter; Thayer, Kristina A

2017-06-13

Decision analysis-a systematic approach to solving complex problems-offers tools and frameworks to support decision making that are increasingly being applied to environmental challenges. Alternatives analysis is a method used in regulation and product design to identify, compare, and evaluate the safety and viability of potential substitutes for hazardous chemicals. We assessed whether decision science may assist the alternatives analysis decision maker in comparing alternatives across a range of metrics. A workshop was convened that included representatives from government, academia, business, and civil society and included experts in toxicology, decision science, alternatives assessment, engineering, and law and policy. Participants were divided into two groups and were prompted with targeted questions. Throughout the workshop, the groups periodically came together in plenary sessions to reflect on other groups' findings. We concluded that the further incorporation of decision science into alternatives analysis would advance the ability of companies and regulators to select alternatives to harmful ingredients and would also advance the science of decision analysis. We advance four recommendations: a ) engaging the systematic development and evaluation of decision approaches and tools; b ) using case studies to advance the integration of decision analysis into alternatives analysis; c ) supporting transdisciplinary research; and d ) supporting education and outreach efforts. https://doi.org/10.1289/EHP483.

Advancing Alternative Analysis: Integration of Decision Science

PubMed Central

Zaunbrecher, Virginia M.; Batteate, Christina M.; Blake, Ann; Carroll, William F.; Corbett, Charles J.; Hansen, Steffen Foss; Lempert, Robert J.; Linkov, Igor; McFadden, Roger; Moran, Kelly D.; Olivetti, Elsa; Ostrom, Nancy K.; Romero, Michelle; Schoenung, Julie M.; Seager, Thomas P.; Sinsheimer, Peter; Thayer, Kristina A.

2017-01-01

Background: Decision analysis—a systematic approach to solving complex problems—offers tools and frameworks to support decision making that are increasingly being applied to environmental challenges. Alternatives analysis is a method used in regulation and product design to identify, compare, and evaluate the safety and viability of potential substitutes for hazardous chemicals. Objectives: We assessed whether decision science may assist the alternatives analysis decision maker in comparing alternatives across a range of metrics. Methods: A workshop was convened that included representatives from government, academia, business, and civil society and included experts in toxicology, decision science, alternatives assessment, engineering, and law and policy. Participants were divided into two groups and were prompted with targeted questions. Throughout the workshop, the groups periodically came together in plenary sessions to reflect on other groups’ findings. Results: We concluded that the further incorporation of decision science into alternatives analysis would advance the ability of companies and regulators to select alternatives to harmful ingredients and would also advance the science of decision analysis. Conclusions: We advance four recommendations: a) engaging the systematic development and evaluation of decision approaches and tools; b) using case studies to advance the integration of decision analysis into alternatives analysis; c) supporting transdisciplinary research; and d) supporting education and outreach efforts. https://doi.org/10.1289/EHP483 PMID:28669940

40 CFR 270.65 - Research, development, and demonstration permits.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) EPA ADMINISTERED PERMIT PROGRAMS: THE HAZARDOUS WASTE PERMIT PROGRAM... may issue a research, development, and demonstration permit for any hazardous waste treatment facility which proposes to utilize an innovative and experimental hazardous waste treatment technology or process...

40 CFR 270.65 - Research, development, and demonstration permits.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) EPA ADMINISTERED PERMIT PROGRAMS: THE HAZARDOUS WASTE PERMIT PROGRAM... may issue a research, development, and demonstration permit for any hazardous waste treatment facility which proposes to utilize an innovative and experimental hazardous waste treatment technology or process...

14 CFR 91.1085 - Hazardous materials recognition training.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 2 2014-01-01 2014-01-01 false Hazardous materials recognition training. 91.1085 Section 91.1085 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Ownership Operations Program Management § 91.1085 Hazardous materials recognition training. No program...

14 CFR 91.1085 - Hazardous materials recognition training.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 2 2012-01-01 2012-01-01 false Hazardous materials recognition training. 91.1085 Section 91.1085 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Ownership Operations Program Management § 91.1085 Hazardous materials recognition training. No program...

14 CFR 91.1085 - Hazardous materials recognition training.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Hazardous materials recognition training. 91.1085 Section 91.1085 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Ownership Operations Program Management § 91.1085 Hazardous materials recognition training. No program...

14 CFR 91.1085 - Hazardous materials recognition training.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 2 2011-01-01 2011-01-01 false Hazardous materials recognition training. 91.1085 Section 91.1085 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Ownership Operations Program Management § 91.1085 Hazardous materials recognition training. No program...

14 CFR 91.1085 - Hazardous materials recognition training.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 2 2013-01-01 2013-01-01 false Hazardous materials recognition training. 91.1085 Section 91.1085 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Ownership Operations Program Management § 91.1085 Hazardous materials recognition training. No program...

SB 1082 -- Unified hazardous materials/waste program: Local implementation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, W.

California Senate Bill 1082 was signed into law in the fall of 1993 because business and industry believed there were too many hazardous materials inspectors asking the same questions, looking at the same items and requiring similar information on several variations of the same form. Industry was not happy with the large diversity of programs, each with its own inspectors, permits and fees, essentially doing what industry believed was the same inspection. SB 1082 will allow local city and county agencies to apply to the California Environmental Protection Agency to become a Certified Unified Program Agency (CUPA) or work withmore » a CUPA as a Participating Agency (PA) to manage specific program elements. The CUPA will unify six regulatory programs including hazardous waste/tiered permitting, aboveground storage tanks, underground storage tanks, business and area plans/inventory or disclosure, acutely hazardous materials/risk management prevention and Uniform Fire Code programs related to hazardous materials inventory/plan requirements. The bill requires the CUPA to (1) implement a permit consolidation program; (2) implement a single fee system with a state surcharge; (3) consolidate, coordinate and make consistent any local or regional requirements or guidance documents; and (4) implement a single unified inspection and enforcement program.« less

Applications of research from the U.S. Geological Survey program, assessment of regional earthquake hazards and risk along the Wasatch Front, Utah

USGS Publications Warehouse

Gori, Paula L.

1993-01-01

INTERACTIVE WORKSHOPS: ESSENTIAL ELEMENTS OF THE EARTHQUAKE HAZARDS RESEARCH AND REDUCTION PROGRAM IN THE WASATCH FRONT, UTAH: Interactive workshops provided the forum and stimulus necessary to foster collaboration among the participants in the multidisciplinary, 5-yr program of earthquake hazards reduction in the Wasatch Front, Utah. The workshop process validated well-documented social science theories on the importance of interpersonal interaction, including interaction between researchers and users of research to increase the probability that research will be relevant to the user's needs and, therefore, more readily used. REDUCING EARTHQUAKE HAZARDS IN UTAH: THE CRUCIAL CONNECTION BETWEEN RESEARCHERS AND PRACTITIONERS: Complex scientific and engineering studies must be translated for and transferred to nontechnical personnel for use in reducing earthquake hazards in Utah. The three elements needed for effective translation, likelihood of occurrence, location, and severity of potential hazards, and the three elements needed for effective transfer, delivery, assistance, and encouragement, are described and illustrated for Utah. The importance of evaluating and revising earthquake hazard reduction programs and their components is emphasized. More than 30 evaluations of various natural hazard reduction programs and techniques are introduced. This report was prepared for research managers, funding sources, and evaluators of the Utah earthquake hazard reduction program who are concerned about effectiveness. An overview of the Utah program is provided for those researchers, engineers, planners, and decisionmakers, both public and private, who are committed to reducing human casualties, property damage, and interruptions of socioeconomic systems. PUBLIC PERCEPTIONS OF THE IMPLEMENTATION OF EARTHQUAKE MITIGATION POLICIES ALONG THE WASATCH FRONT IN UTAH: The earthquake hazard potential along the Wasatch Front in Utah has been well defined by a number of scientific and engineering studies. Translated earthquake hazard maps have also been developed to identify areas that are particularly vulnerable to various causes of damage such as ground shaking, surface rupturing, and liquefaction. The implementation of earthquake hazard reduction plans are now under way in various communities in Utah. The results of a survey presented in this paper indicate that technical public officials (planners and building officials) have an understanding of the earthquake hazards and how to mitigate the risks. Although the survey shows that the general public has a slightly lower concern about the potential for economic losses, they recognize the potential problems and can support a number of earthquake mitigation measures. The study suggests that many community groups along the Wasatch Front, including volunteer groups, business groups, and elected and appointed officials, are ready for action-oriented educational programs. These programs could lead to a significant reduction in the risks associated with earthquake hazards. A DATA BASE DESIGNED FOR URBAN SEISMIC HAZARDS STUDIES: A computerized data base has been designed for use in urban seismic hazards studies conducted by the U.S. Geological Survey. The design includes file structures for 16 linked data sets, which contain geological, geophysical, and seismological data used in preparing relative ground response maps of large urban areas. The data base is organized along relational data base principles. A prototype urban hazards data base has been created for evaluation in two urban areas currently under investigation: the Wasatch Front region of Utah and the Puget Sound area of Washington. The initial implementation of the urban hazards data base was accomplished on a microcomputer using dBASE III Plus software and transferred to minicomputers and a work station. A MAPPING OF GROUND-SHAKING INTENSITIES FOR SALT LAKE COUNTY, UTAH: This paper documents the development of maps showing a

USEPA'S SITE PROGRAM IMPACT ON THE DEVELOPMENT AND USE OF INNOVATIVE HAZARDOUS WASTE TREATMENT

EPA Science Inventory

The USEPA's SITE Program was created to meet the increased demand for innovative technologies for hazardous waste treatment. The primary mission of the SITe Program is to expedite the cleanup of sites on the NPL. The SITE Program has two components: The Demonstration Program and ...

Efficacy of the California Bureau of Land Management Community Assistance and Hazardous Fuels Programs

Treesearch

David J. Ganz; David S. Saah; Matthew A. Wilson; Austin Troy

2007-01-01

This study provides a framework for assessing the social and environmental benefits and public education outcomes associated with the U.S. Department of the Interior, Bureau of Land Management’s Community Assistance and Hazardous Fuel Programs in California. Evaluations of fire hazard mitigation programs tend to focus primarily on the number of acres treated and...

40 CFR 272.1851 - Oklahoma State-administered program: Final authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Oklahoma § 272.1851...)(1)(i) of this section are incorporated by reference as part of the hazardous waste management... Approved Oklahoma Statutory and Regulatory Requirements Applicable to the Hazardous Waste Management...

76 FR 58492 - Agency Information Collection Activities; Proposed Collection; Comment Request; Final...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-21

... Activities; Proposed Collection; Comment Request; Final Authorization for Hazardous Waste Management Programs... Request (ICR) concerning final authorization for State Hazardous Waste Management Programs. This ICR is... potentially affected by this action are States. Title: Final Authorization for Hazardous Waste Management...

Scientific Issues Relevant to Setting Regulatory Criteria to Identify Endocrine-Disrupting Substances in the European Union.

PubMed

Slama, Rémy; Bourguignon, Jean-Pierre; Demeneix, Barbara; Ivell, Richard; Panzica, Giancarlo; Kortenkamp, Andreas; Zoeller, R Thomas

2016-10-01

Endocrine disruptors (EDs) are defined by the World Health Organization (WHO) as exogenous compounds or mixtures that alter function(s) of the endocrine system and consequently cause adverse effects in an intact organism, or its progeny, or (sub)populations. European regulations on pesticides, biocides, cosmetics, and industrial chemicals require the European Commission to establish scientific criteria to define EDs. We address the scientific relevance of four options for the identification of EDs proposed by the European Commission. Option 1, which does not define EDs and leads to using interim criteria unrelated to the WHO definition of EDs, is not relevant. Options 2 and 3 rely on the WHO definition of EDs, which is widely accepted by the scientific community, with option 3 introducing additional categories based on the strength of evidence (suspected EDs and endocrine-active substances). Option 4 adds potency to the WHO definition, as a decision criterion. We argue that potency is dependent on the adverse effect considered and is scientifically ambiguous, and note that potency is not used as a criterion to define other particularly hazardous substances such as carcinogens and reproductive toxicants. The use of potency requires a context that goes beyond hazard identification and corresponds to risk characterization, in which potency (or, more relevantly, the dose-response function) is combined with exposure levels. There is scientific agreement regarding the adequacy of the WHO definition of EDs. The potency concept is not relevant to the identification of particularly serious hazards such as EDs. As is common practice for carcinogens, mutagens, and reproductive toxicants, a multi-level classification of ED based on the WHO definition, and not considering potency, would be relevant (corresponding to option 3 proposed by the European Commission). Slama R, Bourguignon JP, Demeneix B, Ivell R, Panzica G, Kortenkamp A, Zoeller RT. 2016. Scientific issues relevant to setting regulatory criteria to identify endocrine disrupting substances in the European Union. Environ Health Perspect 124:1497-1503; http://dx.doi.org/10.1289/EHP217.

Traffic-Related Air Pollution and All-Cause Mortality during Tuberculosis Treatment in California

PubMed Central

Pascopella, Lisa; Catanzaro, Donald G.; Barry, Pennan M.; English, Paul B.; Segal, Mark R.; Flood, Jennifer; Meltzer, Dan; Jones, Brenda; Balmes, John; Nahid, Payam

2017-01-01

Background: Ambient air pollution and tuberculosis (TB) have an impact on public health worldwide, yet associations between the two remain uncertain. Objective: We determined the impact of residential traffic on mortality during treatment of active TB. Methods: From 2000–2012, we enrolled 32,875 patients in California with active TB and followed them throughout treatment. We obtained patient data from the California Tuberculosis Registry and calculated traffic volumes and traffic densities in 100- to 400-m radius buffers around residential addresses. We used Cox models to determine mortality hazard ratios, controlling for demographic, socioeconomic, and clinical potential confounders. We categorized traffic exposures as quintiles and determined trends using Wald tests. Results: Participants contributed 22,576 person-years at risk. There were 2,305 deaths during treatment for a crude mortality rate of 1,021 deaths per 10,000 person-years. Traffic volumes and traffic densities in all buffers around patient residences were associated with increased mortality during TB treatment, although the findings were not statistically significant in all buffers. As the buffer size decreased, fifth-quintile mortality hazards increased, and trends across quintiles of traffic exposure became more statistically significant. Increasing quintiles of nearest-road traffic volumes in the 100-m buffer were associated with 3%, 14%, 19%, and 28% increased risk of death during TB treatment [first quintile, referent; second quintile hazard ratio (HR)=1.03 [95% confidence interval (CI): 0.86, 1.25]; third quintile HR=1.14 (95% CI: 0.95, 1.37); fourth quintile HR=1.19 (95% CI: 0.99, 1.43); fifth quintile HR=1.28 (95% CI: 1.07, 1.53), respectively; p-trend=0.002]. Conclusions: Residential proximity to road traffic volumes and traffic density were associated with increased all-cause mortality in patients undergoing treatment for active tuberculosis even after adjusting for multiple demographic, socioeconomic, and clinical factors, suggesting that TB patients are susceptible to the adverse health effects of traffic-related air pollution. https://doi.org/10.1289/EHP1699 PMID:28963088

Scientific Issues Relevant to Setting Regulatory Criteria to Identify Endocrine-Disrupting Substances in the European Union

PubMed Central

Slama, Rémy; Bourguignon, Jean-Pierre; Demeneix, Barbara; Ivell, Richard; Panzica, Giancarlo; Kortenkamp, Andreas; Zoeller, R. Thomas

2016-01-01

Background: Endocrine disruptors (EDs) are defined by the World Health Organization (WHO) as exogenous compounds or mixtures that alter function(s) of the endocrine system and consequently cause adverse effects in an intact organism, or its progeny, or (sub)populations. European regulations on pesticides, biocides, cosmetics, and industrial chemicals require the European Commission to establish scientific criteria to define EDs. Objectives: We address the scientific relevance of four options for the identification of EDs proposed by the European Commission. Discussion: Option 1, which does not define EDs and leads to using interim criteria unrelated to the WHO definition of EDs, is not relevant. Options 2 and 3 rely on the WHO definition of EDs, which is widely accepted by the scientific community, with option 3 introducing additional categories based on the strength of evidence (suspected EDs and endocrine-active substances). Option 4 adds potency to the WHO definition, as a decision criterion. We argue that potency is dependent on the adverse effect considered and is scientifically ambiguous, and note that potency is not used as a criterion to define other particularly hazardous substances such as carcinogens and reproductive toxicants. The use of potency requires a context that goes beyond hazard identification and corresponds to risk characterization, in which potency (or, more relevantly, the dose–response function) is combined with exposure levels. Conclusions: There is scientific agreement regarding the adequacy of the WHO definition of EDs. The potency concept is not relevant to the identification of particularly serious hazards such as EDs. As is common practice for carcinogens, mutagens, and reproductive toxicants, a multi-level classification of ED based on the WHO definition, and not considering potency, would be relevant (corresponding to option 3 proposed by the European Commission). Citation: Slama R, Bourguignon JP, Demeneix B, Ivell R, Panzica G, Kortenkamp A, Zoeller RT. 2016. Scientific issues relevant to setting regulatory criteria to identify endocrine disrupting substances in the European Union. Environ Health Perspect 124:1497–1503; http://dx.doi.org/10.1289/EHP217 PMID:27108591

Moving to a Highly Walkable Neighborhood and Incidence of Hypertension: A Propensity-Score Matched Cohort Study.

PubMed

Chiu, Maria; Rezai, Mohammad-Reza; Maclagan, Laura C; Austin, Peter C; Shah, Baiju R; Redelmeier, Donald A; Tu, Jack V

2016-06-01

The impact of moving to a neighborhood more conducive to utilitarian walking on the risk of incident hypertension is uncertain. Our study aimed to examine the effect of moving to a highly walkable neighborhood on the risk of incident hypertension. A population-based propensity-score matched cohort study design was used based on the Ontario population from the Canadian Community Health Survey (2001-2010). Participants were adults ≥ 20 years of age who moved from a low-walkability neighborhood (defined as any neighborhood with a Walk Score < 90) to either a high- (Walk Score ≥ 90) or another low-walkability neighborhood. The incidence of hypertension was assessed by linking the cohort to administrative health databases using a validated algorithm. Propensity-score matched Cox proportional hazard models were used. Annual health examination was used as a control event. Among the 1,057 propensity-score matched pairs there was a significantly lower risk of incident hypertension in the low to high vs. the low to low-walkability groups [hazard ratio = 0.46; 95% CI, 0.26, 0.81, p < 0.01]. The crude hypertension incidence rates were 18.0 per 1,000 person-years (95% CI: 11.6, 24.8) among the low- to low-walkability movers compared with 8.6 per 1,000 person-years (95% CI: 5.3, 12.7) among the low- to high-walkability movers (p < 0.001). There were no significant differences in the hazard of annual health examination between the two mover groups. Moving to a highly walkable neighborhood was associated with a significantly lower risk of incident hypertension. Future research should assess whether specific attributes of walkable neighborhoods (e.g., amenities, density, land-use mix) may be driving this relationship. Chiu M, Rezai MR, Maclagan LC, Austin PC, Shah BR, Redelmeier DA, Tu JV. 2016. Moving to a highly walkable neighborhood and incidence of hypertension: a propensity-score matched cohort study. Environ Health Perspect 124:754-760; http://dx.doi.org/10.1289/ehp.1510425.

10 CFR 850.21 - Hazard assessment.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Hazard assessment. 850.21 Section 850.21 Energy DEPARTMENT OF ENERGY CHRONIC BERYLLIUM DISEASE PREVENTION PROGRAM Specific Program Requirements § 850.21 Hazard... with the greatest risks of exposure are evaluated first. (b) The responsible employer must ensure that...

Publications - GMC 233 | Alaska Division of Geological & Geophysical

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in geologic field program in Lower Cook Inlet, Alaska Authors: Roberts, Chuck, Coastal Science Laboratories publication sales page for more information. Bibliographic Reference Roberts, Chuck, Coastal Science

75 FR 60457 - Underground Injection Control Program Hazardous Waste Injection Restrictions; Petition for...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-30

... ENVIRONMENTAL PROTECTION AGENCY [FRL-9208-4] Underground Injection Control Program Hazardous Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection Dow Chemical Company (DOW... Petition. SUMMARY: Notice is hereby given that an exemption to the land disposal restrictions under the...

78 FR 42776 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-17

... ENVIRONMENTAL PROTECTION AGENCY [FRL9834-8] Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection; Blanchard Refining... migration petition reissuance. SUMMARY: Notice is hereby given that a reissuance of an exemption to the land...

Preliminary results of the U.S. Nuclear Regulatory Commission collaborative research program to assess tsunami hazard for nuclear power plants on the Atlantic and gulf coasts

USGS Publications Warehouse

Kammerer, A.M.; ten Brink, Uri S.; Twitchell, David C.; Geist, Eric L.; Chaytor, Jason D.; Locat, J.; Lee, H.J.; Buczkowski, Brian J.; Sansoucy, M.

2008-01-01

In response to the 2004 Indian Ocean Tsunami, the United States Nuclear Regulatory Commission (US NRC) initiated a long-term research program to improve understanding of tsunami hazard levels for nuclear facilities in the United States. For this effort, the US NRC organized a collaborative research program with the United States Geological Survey (USGS) and other key researchers for the purpose of assessing tsunami hazard on the Atlantic and Gulf Coasts of the United States. The initial phase of this work consisted principally of collection, interpretation, and analysis of available offshore data and information. Necessarily, the US NRC research program includes both seismic- and landslide-based tsunamigenic sources in both the near and the far fields. The inclusion of tsunamigenic landslides, an important category of sources that impact tsunami hazard levels for the Atlantic and Gulf Coasts over the long time periods of interest to the US NRC is a key difference between this program and most other tsunami hazard assessment programs. Although only a few years old, this program is already producing results that both support current US NRC activities and look toward the long-term goal of probabilistic tsunami hazard assessment. This paper provides a summary of results from several areas of current research. An overview of the broader US NRC research program is provided in a companion paper in this conference.

Technical assistance for hazardous-waste reduction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thompson, F.M.; McComas, C.A.

1987-12-01

Minnesota's Waste Management Board has established, developed, and funded the Minnesota Technical Assistance Program (MnTAP). The MnTAP programs offers technical assistance to generators of hazardous waste by offering telephone and onsite consultation, a waste reduction resource bank, information dissemination, a student intern program, and research awards for waste reduction projects. The program has completed three years of successful operation. The increasing interest in and use of MnTAP's services by hazardous-waste generators has justified the belief that state technical assistance programs have an important role to play in helping generators to reduce their waste production.

Volcano Hazards Program

USGS Publications Warehouse

Venezky, Dina Y.; Myers, Bobbie; Driedger, Carolyn

2008-01-01

Diagram of common volcano hazards. The U.S. Geological Survey Volcano Hazards Program (VHP) monitors unrest and eruptions at U.S. volcanoes, assesses potential hazards, responds to volcanic crises, and conducts research on how volcanoes work. When conditions change at a monitored volcano, the VHP issues public advisories and warnings to alert emergency-management authorities and the public. See http://volcanoes.usgs.gov/ to learn more about volcanoes and find out what's happening now.

Efficient management of cardiovascular risk screening programs

NASA Technical Reports Server (NTRS)

Roth, Carol

1993-01-01

The Environmental Health Unit, located on-site at the the Goddard Space Flight Center (GSFC), is responsible for the implementation of the Center's Employee Environmental and Occupational Health Program. The Health Unit, Health Physics (HP), and Industrial Hygiene (IH) staffs collaborate to provide quality service to the employees at GSFC. The Health Unit staff identifies, evaluates, and ensures the control of occupational hazards on the Center. In the past, components of the Industrial Hygiene Program have included the Industrial Hygiene Health Hazard Identification Program (IHHIP), the Hearing Conservation Program (HCP), the Hazard Communication Program, and the bi-annual fume hood survey. More recently, the Environmental Health Unit has expanded its services by adding the Ergonomics Program. Various aspects of the Ergonomics Program are discussed.

Hazardous waste management in the Pacific basin

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cirillo, R.R.; Chiu, S.; Chun, K.C.

1994-11-01

Hazardous waste control activities in Asia and the Pacific have been reviewed. The review includes China (mainland, Hong Kong, and Taiwan), Indonesia, Korea, Malaysia, Papua New Guinea, the Philippines, Singapore, and Thailand. It covers the sources of hazardous waste, the government structure for dealing with hazardous waste, and current hazardous waste control activities in each country. In addition, the hazardous waste program activities of US government agencies, US private-sector organizations, and international organizations are reviewed. The objective of these reviews is to provide a comprehensive picture of the current hazardous waste problems and the waste management approaches being used tomore » address them so that new program activities can be designed more efficiently.« less

44 CFR 79.3 - Responsibilities.

Code of Federal Regulations, 2011 CFR

2011-10-01

... HOMELAND SECURITY INSURANCE AND HAZARD MITIGATION National Flood Insurance Program FLOOD MITIGATION GRANTS... oversight to all FEMA-related hazard mitigation programs and grants, including: (1) Issue program... Indian tribal governments regarding the mitigation and grants management process; (5) Review and approve...

44 CFR 79.3 - Responsibilities.

Code of Federal Regulations, 2014 CFR

2014-10-01

... HOMELAND SECURITY INSURANCE AND HAZARD MITIGATION National Flood Insurance Program FLOOD MITIGATION GRANTS... oversight to all FEMA-related hazard mitigation programs and grants, including: (1) Issue program... Indian tribal governments regarding the mitigation and grants management process; (5) Review and approve...

44 CFR 79.3 - Responsibilities.

Code of Federal Regulations, 2013 CFR

2013-10-01

... HOMELAND SECURITY INSURANCE AND HAZARD MITIGATION National Flood Insurance Program FLOOD MITIGATION GRANTS... oversight to all FEMA-related hazard mitigation programs and grants, including: (1) Issue program... Indian tribal governments regarding the mitigation and grants management process; (5) Review and approve...

44 CFR 79.3 - Responsibilities.

Code of Federal Regulations, 2012 CFR

2012-10-01

... SECURITY INSURANCE AND HAZARD MITIGATION National Flood Insurance Program FLOOD MITIGATION GRANTS § 79.3...-related hazard mitigation programs and grants, including: (1) Issue program implementation procedures, as... governments regarding the mitigation and grants management process; (5) Review and approve State, Indian...

44 CFR 79.3 - Responsibilities.

Code of Federal Regulations, 2010 CFR

2010-10-01

... HOMELAND SECURITY INSURANCE AND HAZARD MITIGATION National Flood Insurance Program FLOOD MITIGATION GRANTS... oversight to all FEMA-related hazard mitigation programs and grants, including: (1) Issue program... Indian tribal governments regarding the mitigation and grants management process; (5) Review and approve...

Hazardous Materials Emergency Preparedness grants program : assessment of the alignment between local activities and program goals

DOT National Transportation Integrated Search

2005-10-01

This report has been commissioned as a first step in determining the extent of the links between the HMEP Grants Program and the DOT hazardous materials program, and in identifying opportunities to strengthen these links. It presents findings from an...

Algorithmic Skin: Health-Tracking Technologies, Personal Analytics and the Biopedagogies of Digitized Health and Physical Education

ERIC Educational Resources Information Center

Williamson, Ben

2015-01-01

The emergence of digitized health and physical education, or "eHPE", embeds software algorithms in the organization of health and physical education pedagogies. Particularly with the emergence of wearable and mobile activity trackers, biosensors and personal analytics apps, algorithmic processes have an increasingly powerful part to play…

78 FR 31967 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-28

... Historic Preservation Environmental Screening Form. DATES: Comments must be submitted on or before July 29... authorities through one consolidated process. With input from grantees, the EHP Screening Form was revised for clarity and ease of use. The 2013 Screening Form does not require any new information, and includes an...

eHPE: A History of the Future

ERIC Educational Resources Information Center

Gard, Michael

2014-01-01

A grand convergence looms. It seems at least plausible that health and physical education may soon be lived by students in ways that are radically different from the past and sharply at odds with the imaginings of its founders and generations of academic aficionados. Perhaps in some respects, the differences will be superficial and less important…

Photoluminescence of silicon nanowires obtained by epitaxial chemical vapor deposition

NASA Astrophysics Data System (ADS)

Demichel, O.; Oehler, F.; Calvo, V.; Noé, P.; Pauc, N.; Gentile, P.; Ferret, P.; Baron, T.; Magnea, N.

2009-05-01

We have carried out photoluminescence measurements of silicon nanowires (SiNWs) obtained by the chemical vapor deposition method with a copper-catalyzed vapor-liquid-solid mechanism. The nanowires have a typical diameter of 200 nm. Spectrum of the as-grown SiNWs exhibits radiative states below the energy bandgap and a small contribution near the silicon gap energy at 1.08 eV. A thermal oxidation allows to decrease the intensity at low energy and to enhance the intensity of the 1.08 eV contribution. The behavior of this contribution as a function of the pump power is correlated to a free carrier recombination. Furthermore, the spatial confinement of the carriers in SiNWs could explain the difference of shape and recombination energy of this contribution compared to the recombination of free exciton in the bulk silicon. The electronic system seems to be in an electron-hole plasma (ehp), as it has already been shown in SOI structures [M. Tajima, et al., J. Appl. Phys. 84 (1998) 2224]. A simulation of the radiative emission of an ehp is performed and results are discussed.

USEPA SITE PROGRAM APPROACH TO TECHNOLOGY TRANSFER AND REGULATORY ACCEPTANCE

EPA Science Inventory

The SITE Program was created to meet the increased demand for innovative technologies for hazardous waste treatment. To accomplish this mission, the program seeks to advance the development, implementation and commercialization of innovative technologies for hazardous waste chara...

40 CFR 270.13 - Contents of part A of the permit application.

Code of Federal Regulations, 2011 CFR

2011-07-01

... WASTES (CONTINUED) EPA ADMINISTERED PERMIT PROGRAMS: THE HAZARDOUS WASTE PERMIT PROGRAM Permit..., and disposing of hazardous waste, and the design capacity of these items. (j) A specification of the hazardous wastes listed or designated under 40 CFR part 261 to be treated, stored, or disposed of at the...

40 CFR 270.13 - Contents of part A of the permit application.

Code of Federal Regulations, 2010 CFR

2010-07-01

... WASTES (CONTINUED) EPA ADMINISTERED PERMIT PROGRAMS: THE HAZARDOUS WASTE PERMIT PROGRAM Permit..., and disposing of hazardous waste, and the design capacity of these items. (j) A specification of the hazardous wastes listed or designated under 40 CFR part 261 to be treated, stored, or disposed of at the...

Proceedings of Conference V: communicating earthquake hazard reduction information: convened under auspices of National Earthquake Hazards Reduction Program 22-24 May, 1978

USGS Publications Warehouse

Hays, Walter W.

1978-01-01

(11) achieving landslide hazard reduction. The objective was to identify the most significant lessons learned during the course of each experience and to develop recommendations for improving communication that might be incorporated in the search program of the USGS.

76 FR 28803 - Notice of Availability: Notice of Funding Availability (NOFA) for HUD's Fiscal Year (FY) 2011...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-18

...: Notice of Funding Availability (NOFA) for HUD's Fiscal Year (FY) 2011 Lead-Based Paint Hazard Control Grant Program and Lead Hazard Reduction Demonstration Grant Program and Amendment and Technical Corrections AGENCY: Office of Healthy Homes and Lead Hazard Control, HUD. ACTION: Notice of Availability and...

Hazardous Materials Technology: A Community College's Response to a Critical Employment Need.

ERIC Educational Resources Information Center

Friedel, Janice N.; And Others

Studies conducted by the Eastern Iowa Community College District in 1986 revealed a lack of credit programs and curricula for training individuals in the technical aspects of hazardous materials management and need for hazardous materials technicians by local industry. In response, an associate of applied science (AAS) degree program in Hazardous…

EPA issues interim final waste minimization guidance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bergeson, L.L.

1993-08-01

The U.S. Environmental Protection Agency (EPA) has released a new and detailed interim final guidance to assist hazardous waste generators in certifying they have a waste minimization program in place under the Resource Conservation and Recovery Act (RCRA). EPA's guidance identifies the basic elements of a waste minimization program in place that, if present, will allow people to certify they have implemented a program to reduce the volume and toxicity of hazardous waste to the extent economically practical. The guidance is directly applicable to generators of 1000 or more kilograms per month of hazardous waste, or large-quantity generators, and tomore » owners and operators of hazardous waste treatment, storage or disposal facilities who manage their own hazardous waste on site. Small-quantity generators that generate more than 100 kilograms, but less than 1,000 kilograms, per month of hazardous waste are not subject to the same program in place certification requirement. Rather, they must certify on their manifests that they have made a good faith effort to minimize their waste generation.« less

Effects of Absorbing Aerosols on Accelerated Melting of Snowpack in the Hindu-Kush-Himalayas-Tibetan Plateau Region

NASA Technical Reports Server (NTRS)

Lau, William K.; Kyu-Myong, Kim; Yasunari, Teppei; Gautam, Ritesh; Hsu, Christina

2011-01-01

The impacts of absorbing aerosol on melting of snowpack in the Hindu-Kush-Himalayas-Tibetan Plateau (HKHT) region are studied using in-situ, satellite observations, and GEOS-5 GCM. Based on atmospheric black carbon measurements from the Pyramid observation ( 5 km elevation) in Mt. Everest, we estimate that deposition of black carbon on snow surface will give rise to a reduction in snow surface albedo of 2- 5 %, and an increased annual runoff of 12-34% for a typical Tibetan glacier. Examination of satellite reflectivity and re-analysis data reveals signals of possible impacts of dust and black carbon in darkening the snow surface, and accelerating spring melting of snowpack in the HKHT, following a build-up of absorbing aerosols in the Indo-Gangetic Plain. Results from GCM experiments show that 8-10% increase in the rate of melting of snowpack over the western Himalayas and Tibetan Plateau can be attributed to the elevated-heat-pump (EHP) feedback effect, initiated from the absorption of solar radiation by dust and black carbon accumulated to great height ( 5 km) over the Indo-Gangetic Plain and Himalayas foothills in the pre-monsoon season (April-May). The accelerated melting of the snowpack is enabled by an EHP-induced atmosphere-land-snowpack positive feedback involving a) orographic forcing of the monsoon flow by the complex terrain, and thermal forcing of the HKHT region, leading to increased moisture, cloudiness and rainfall over the Himalayas foothills and northern India, b) warming of the upper troposphere over the Tibetan Plateau, and c) an snow albedo-temperature feedback initiated by a transfer of latent and sensible heat from a warmer atmosphere over the HKHT to the underlying snow surface. Results from ongoing modeling work to assess the relative roles of EHP vs. snow-darkening effects on accelerated melting of snowpack in HKHT region will also be discussed.

The Role and Quality of Software Safety in the NASA Constellation Program

NASA Technical Reports Server (NTRS)

Layman, Lucas; Basili, Victor R.; Zelkowitz, Marvin V.

2010-01-01

In this study, we examine software safety risk in the early design phase of the NASA Constellation spaceflight program. Obtaining an accurate, program-wide picture of software safety risk is difficult across multiple, independently-developing systems. We leverage one source of safety information, hazard analysis, to provide NASA quality assurance managers with information regarding the ongoing state of software safety across the program. The goal of this research is two-fold: 1) to quantify the relative importance of software with respect to system safety; and 2) to quantify the level of risk presented by software in the hazard analysis. We examined 154 hazard reports created during the preliminary design phase of three major flight hardware systems within the Constellation program. To quantify the importance of software, we collected metrics based on the number of software-related causes and controls of hazardous conditions. To quantify the level of risk presented by software, we created a metric scheme to measure the specificity of these software causes. We found that from 49-70% of hazardous conditions in the three systems could be caused by software or software was involved in the prevention of the hazardous condition. We also found that 12-17% of the 2013 hazard causes involved software, and that 23-29% of all causes had a software control. Furthermore, 10-12% of all controls were software-based. There is potential for inaccuracy in these counts, however, as software causes are not consistently scoped, and the presence of software in a cause or control is not always clear. The application of our software specificity metrics also identified risks in the hazard reporting process. In particular, we found a number of traceability risks in the hazard reports may impede verification of software and system safety.

Ab initio molecular dynamics calculations on scattering of hyperthermal H atoms from Cu(111) and Au(111)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kroes, Geert-Jan, E-mail: g.j.kroes@chem.leidenuniv.nl; Pavanello, Michele; Blanco-Rey, María

2014-08-07

Energy loss from the translational motion of an atom or molecule impinging on a metal surface to the surface may determine whether the incident particle can trap on the surface, and whether it has enough energy left to react with another molecule present at the surface. Although this is relevant to heterogeneous catalysis, the relative extent to which energy loss of hot atoms takes place to phonons or electron-hole pair (ehp) excitation, and its dependence on the system's parameters, remain largely unknown. We address these questions for two systems that present an extreme case of the mass ratio of themore » incident atom to the surface atom, i.e., H + Cu(111) and H + Au(111), by presenting adiabatic ab initio molecular dynamics (AIMD) predictions of the energy loss and angular distributions for an incidence energy of 5 eV. The results are compared to the results of AIMDEFp calculations modeling energy loss to ehp excitation using an electronic friction (“EF”) model applied to the AIMD trajectories, so that the energy loss to the electrons is calculated “post” (“p”) the computation of the AIMD trajectory. The AIMD calculations predict average energy losses of 0.38 eV for Cu(111) and 0.13-0.14 eV for Au(111) for H-atoms that scatter from these surfaces without penetrating the surface. These energies closely correspond with energy losses predicted with Baule models, which is suggestive of structure scattering. The predicted adiabatic integral energy loss spectra (integrated over all final scattering angles) all display a lowest energy peak at an energy corresponding to approximately 80% of the average adiabatic energy loss for non-penetrative scattering. In the adiabatic limit, this suggests a way of determining the approximate average energy loss of non-penetratively scattered H-atoms from the integral energy loss spectrum of all scattered H-atoms. The AIMDEFp calculations predict that in each case the lowest energy loss peak should show additional energy loss in the range 0.2-0.3 eV due to ehp excitation, which should be possible to observe. The average non-adiabatic energy losses for non-penetrative scattering exceed the adiabatic losses to phonons by 0.9-1.0 eV. This suggests that for scattering of hyperthermal H-atoms from coinage metals the dominant energy dissipation channel should be to ehp excitation. These predictions can be tested by experiments that combine techniques for generating H-atom beams that are well resolved in translational energy and for detecting the scattered atoms with high energy-resolution.« less

44 CFR 79.1 - Purpose.

Code of Federal Regulations, 2011 CFR

2011-10-01

... INSURANCE AND HAZARD MITIGATION National Flood Insurance Program FLOOD MITIGATION GRANTS § 79.1 Purpose. (a... the hazard mitigation grant programs made available under the National Flood Insurance Act of 1968, as... Repetitive Loss (SRL) and Flood Mitigation Assistance (FMA) grant programs mitigate losses from floods...

44 CFR 79.1 - Purpose.

Code of Federal Regulations, 2014 CFR

2014-10-01

... INSURANCE AND HAZARD MITIGATION National Flood Insurance Program FLOOD MITIGATION GRANTS § 79.1 Purpose. (a... the hazard mitigation grant programs made available under the National Flood Insurance Act of 1968, as... Repetitive Loss (SRL) and Flood Mitigation Assistance (FMA) grant programs mitigate losses from floods...

44 CFR 79.1 - Purpose.

Code of Federal Regulations, 2012 CFR

2012-10-01

... INSURANCE AND HAZARD MITIGATION National Flood Insurance Program FLOOD MITIGATION GRANTS § 79.1 Purpose. (a... the hazard mitigation grant programs made available under the National Flood Insurance Act of 1968, as... Repetitive Loss (SRL) and Flood Mitigation Assistance (FMA) grant programs mitigate losses from floods...

44 CFR 79.1 - Purpose.

Code of Federal Regulations, 2013 CFR

2013-10-01

... INSURANCE AND HAZARD MITIGATION National Flood Insurance Program FLOOD MITIGATION GRANTS § 79.1 Purpose. (a... the hazard mitigation grant programs made available under the National Flood Insurance Act of 1968, as... Repetitive Loss (SRL) and Flood Mitigation Assistance (FMA) grant programs mitigate losses from floods...

7 CFR 4280.36 - Other laws that contain compliance requirements for these Programs.

Code of Federal Regulations, 2010 CFR

2010-01-01

... U.S.C. 1352, and 7 CFR part 3018, are applicable to these Programs. (j) Earthquake hazards. These Programs are subject to the seismic requirements of the Earthquake Hazards Reduction Act of 1977 (42 U.S.C...

7 CFR 4280.36 - Other laws that contain compliance requirements for these Programs.

Code of Federal Regulations, 2013 CFR

2013-01-01

... U.S.C. 1352, and 7 CFR part 3018, are applicable to these Programs. (j) Earthquake hazards. These Programs are subject to the seismic requirements of the Earthquake Hazards Reduction Act of 1977 (42 U.S.C...

7 CFR 4280.36 - Other laws that contain compliance requirements for these Programs.

Code of Federal Regulations, 2012 CFR

2012-01-01

... U.S.C. 1352, and 7 CFR part 3018, are applicable to these Programs. (j) Earthquake hazards. These Programs are subject to the seismic requirements of the Earthquake Hazards Reduction Act of 1977 (42 U.S.C...

7 CFR 4280.36 - Other laws that contain compliance requirements for these Programs.

Code of Federal Regulations, 2014 CFR

2014-01-01

... U.S.C. 1352, and 7 CFR part 3018, are applicable to these Programs. (j) Earthquake hazards. These Programs are subject to the seismic requirements of the Earthquake Hazards Reduction Act of 1977 (42 U.S.C...

7 CFR 4280.36 - Other laws that contain compliance requirements for these Programs.

Code of Federal Regulations, 2011 CFR

2011-01-01

... U.S.C. 1352, and 7 CFR part 3018, are applicable to these Programs. (j) Earthquake hazards. These Programs are subject to the seismic requirements of the Earthquake Hazards Reduction Act of 1977 (42 U.S.C...

76 FR 4276 - Hazardous Materials: Improving the Safety of Railroad Transportation of Hazardous Materials

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-25

...-0004] Hazardous Materials: Improving the Safety of Railroad Transportation of Hazardous Materials... hazardous materials program. DATES: The public meeting will be held on Tuesday, February 22, 2011, starting...--Hazardous Materials, FRA Office of Safety Assurance and Compliance, at least 4 business days before the date...

Transportation of Hazardous Materials Emergency Preparedness Hazards Assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Blanchard, A.

This report documents the Emergency Preparedness Hazards Assessment (EPHA) for the Transportation of Hazardous Materials (THM) at the Department of Energy (DOE) Savannah River Site (SRS). This hazards assessment is intended to identify and analyze those transportation hazards significant enough to warrant consideration in the SRS Emergency Management Program.

78 FR 35054 - Proposed Collection; Comment Request; Program to Prevent Smoking in Hazardous Areas (Pertains to...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-11

...; Program to Prevent Smoking in Hazardous Areas (Pertains to Underground Coal Mines) AGENCY: Mine Safety and... Act), 30 U.S.C. 877(c), and 30 CFR 75.1702 prohibits persons from smoking or carrying smoking... carrying smoking materials, matches, or lighters underground and to prevent smoking in hazardous areas...

A joint labor-management hazard communication training program: a case study in worker health and safety training.

PubMed

Robins, T G; Hugentobler, M K; Kaminski, M; Klitzman, S

1994-01-01

The 1983 OSHA Hazard Communication Standard requires training of employees exposed to hazardous chemicals. The authors provide a detailed look at the successes and failures of a joint labor-management training program that was designed to bring a firm with more than 50 manufacturing facilities into compliance with the standard.

75 FR 45149 - Announcement of Funding Awards for Healthy Homes and Lead Hazard Control Grant Programs for...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-02

... announced in a Federal Register notice published on May 22, 2009 for Lead Based Paint Hazard Control and... for the Lead Based Paint Hazard Control Grant Program under the Consolidated Appropriations Act, 2009... Tahoe, 1901 Airport Road, Suite 107, South Lake Tahoe, CA 96150, $1,500,000; State of Connecticut...

40 CFR 68.67 - Process hazard analysis.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.67 Process hazard analysis. (a... instrumentation with alarms, and detection hardware such as hydrocarbon sensors.); (4) Consequences of failure of...

40 CFR 68.67 - Process hazard analysis.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.67 Process hazard analysis. (a... instrumentation with alarms, and detection hardware such as hydrocarbon sensors.); (4) Consequences of failure of...

75 FR 82362 - Nonfederal Oil and Gas Development Within the Boundaries of Units of the National Park System...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-30

... species, water resources, soils, vegetation, wetlands, air resources, night skies, wildlife, cultural..., Associate Director for Natural Resources Stewardship and Science, 1849 C Street, NW., Room 3130, Washington... Stewardship and Science. [FR Doc. 2010-32545 Filed 12-29-10; 8:45 am] BILLING CODE 4310-EH-P ...

Topical Hazard Evaluation Program of Candidate Insect Repellent AI3-20816-a, US Department of Agriculture Proprietary Compound, September 1978-November 1980.

DTIC Science & Technology

1981-02-11

GROUND, MD 21010 TOPICAL HAZARD EVALUATION PROGRAM OF CANDIDATE INSECT REPELLENT AI 3- 20816 -aUS DEPARTMENT OF AGRICULTURE PROPRIETARY COMPOUND STUDY NO...irritation A13- 20816 -a Photochemical irritation Topical Hazard Evaluation Sensitization Candidate repellent ALD Skin irritation 20. ABSTRACT (Continue an...reverse e e if necessary and identify by block number) A hazard evaluation of candidate insect repellent A13- 20816 -a was performed by means of laboratory

Publications - RI 97-15D | Alaska Division of Geological & Geophysical

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in Coastal and River; Coastal and River Hazards; Construction Materials; Derivative; Engineering; Engineering

Overview of the U.S. Nuclear Regulatory Commission collaborative research program to assess tsunami hazard for nuclear power plants on the Atlantic and Gulf Coasts

USGS Publications Warehouse

Kammerer, A.M.; ten Brink, Uri S.; Titov, V.V.

2017-01-01

In response to the 2004 Indian Ocean Tsunami, the United States Nuclear Regulatory Commission (US NRC) initiated a long-term research program to improve understanding of tsunami hazard levels for nuclear facilities in the United States. For this effort, the US NRC organized a collaborative research program with the United States Geological Survey (USGS) and the National Oceanic and Atmospheric Administration (NOAA) with a goal of assessing tsunami hazard on the Atlantic and Gulf Coasts of the United States. Necessarily, the US NRC research program includes both seismic- and landslide-based tsunamigenic sources in both the near and the far fields. The inclusion of tsunamigenic landslides, an important category of sources that impact tsunami hazard levels for the Atlantic and Gulf Coasts is a key difference between this program and most other tsunami hazard assessment programs. The initial phase of this work consisted of collection, interpretation, and analysis of available offshore data, with significant effort focused on characterizing offshore near-field landslides and analyzing their tsunamigenic potential and properties. In the next phase of research, additional field investigations will be conducted in key locations of interest and additional analysis will be undertaken. Simultaneously, the MOST tsunami generation and propagation model used by NOAA will first be enhanced to include landslide-based initiation mechanisms and then will be used to investigate the impact of the tsunamigenic sources identified and characterized by the USGS. The potential for probabilistic tsunami hazard assessment will also be explore in the final phases of the program.

40 CFR 272.401 - State-administered program: Final authorization.

Code of Federal Regulations, 2014 CFR

2014-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Delaware § 272.401 State... regulations cited in this paragraph are incorporated by reference and made a part of the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. This incorporation by reference was...

40 CFR 272.401 - State-administered program: Final authorization.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Delaware § 272.401 State... regulations cited in this paragraph are incorporated by reference and made a part of the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. This incorporation by reference was...

40 CFR 272.401 - State-administered program: Final authorization.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Delaware § 272.401 State... regulations cited in this paragraph are incorporated by reference and made a part of the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. This incorporation by reference was...

40 CFR 272.401 - State-administered program: Final authorization.

Code of Federal Regulations, 2013 CFR

2013-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Delaware § 272.401 State... regulations cited in this paragraph are incorporated by reference and made a part of the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. This incorporation by reference was...

Exposure to Hazardous Chemical Substances--A Major Campus Environmental Health & Safety Concern.

ERIC Educational Resources Information Center

Robinson, Donald A.; Sorensen, Alfred J.

1980-01-01

A broad spectrum of potentially hazardous chemicals offers serious exposure risks to members of college and university communities. A formal program is needed to minimize exposure to these substances and maintain a prevention oriented protective program. The University of Massachusetts has developed such a program. (JN)

40 CFR 239.4 - Narrative description of state permit program.

Code of Federal Regulations, 2010 CFR

2010-07-01

...-hazardous waste disposal units that receive CESQG hazardous waste, January 1, 1998. (e) A discussion of... WASTES REQUIREMENTS FOR STATE PERMIT PROGRAM DETERMINATION OF ADEQUACY State Program Application § 239.4...; (d) The number of facilities within the state's jurisdiction that received waste on or after the...

77 FR 10718 - Request for Proposals: 2012 Hazardous Fuels Woody Biomass Utilization Grant Program

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-23

... DEPARTMENT OF AGRICULTURE Forest Service Request for Proposals: 2012 Hazardous Fuels Woody Biomass Utilization Grant Program AGENCY: Forest Service, USDA. ACTION: Notice; Correction. SUMMARY: The Department of... Biomass Coordinator as listed in the addresses above or contact Susan LeVan-Green, Program Manager of the...

33 CFR 150.625 - What must the hazard communication program contain?

Code of Federal Regulations, 2010 CFR

2010-07-01

... OF HOMELAND SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: OPERATIONS Workplace Safety and...) Each deepwater port must have a hazard communication program available for the training of, and review by, all personnel on the deepwater port. (b) The program must be in writing and describe or include...

40 CFR 272.401 - State-administered program: Final authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Delaware § 272.401 State... regulations cited in this paragraph are incorporated by reference and made a part of the hazardous waste management program under Subtitle C of RCRA, 42 U.S.C. 6921 et seq. This incorporation by reference was...

44 CFR 65.16 - Standard Flood Hazard Determination Form and Instructions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Standard Flood Hazard... MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY INSURANCE AND HAZARD MITIGATION National Flood Insurance Program IDENTIFICATION AND MAPPING OF SPECIAL HAZARD AREAS § 65.16 Standard Flood Hazard Determination...

Evaluation of a community based childhood injury prevention program.

PubMed Central

Bablouzian, L.; Freedman, E. S.; Wolski, K. E.; Fried, L. E.

1997-01-01

OBJECTIVES: This pilot study evaluates the effectiveness of a community based childhood injury prevention program on the reduction of home hazards. METHODS: High risk pregnant women, who were enrolled in a home visiting program that augments existing health and human services, received initial home safety assessments. Clients received education about injury prevention practices, in addition to receiving selected home safety supplies. Fourteen questions from the initial assessment tool were repeated upon discharge from the program. Matched analyses were conducted to evaluate differences from initial assessment to discharge. RESULTS: A significantly larger proportion of homes were assessed as safe at discharge, compared with the initial assessment, for the following hazards: children riding unbuckled in all auto travel, Massachusetts Poison Center sticker on the telephone, outlet plugs in all unused electrical outlets, safety latches on cabinets and drawers, and syrup of ipecac in the home. CONCLUSIONS: A community based childhood injury prevention program providing education and safety supplies to clients significantly reduced four home hazards for which safety supplies were provided. Education and promotion of the proper use of child restraint systems in automobiles significantly reduced a fifth hazard, children riding unbuckled in auto travel. This program appears to reduce the prevalence of home hazards and, therefore, to increase home safety. PMID:9113841

Publications - RI 97-15E | Alaska Division of Geological & Geophysical

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in Metadata - Read me Keywords Avalanche; Coastal and River; Coastal and River Hazards; Derivative; Earthquake

Publications - PDF 98-37D | Alaska Division of Geological & Geophysical

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in - Read me Keywords Coastal and River; Coastal and River Hazards; Construction Materials; Decorative Stone

75 FR 3912 - Agency Information Collection Activities: Proposed Collection; Comment Request, 1660-0076; Hazard...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-25

... Mitigation Grant Program Application and Reporting AGENCY: Federal Emergency Management Agency, DHS. ACTION... Hazard Mitigation Grant Program application and reporting requirements. DATES: Comments must be submitted... . [[Page 3913

49 CFR 107.1 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS AND OIL TRANSPORTATION HAZARDOUS MATERIALS PROGRAM..., Pipeline and Hazardous Materials Safety Administration. Competent Authority means a national agency that is responsible, under its national law, for the control or regulation of some aspect of hazardous materials...

Publications - MP 133 v. 2 | Alaska Division of Geological & Geophysical

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in Maps; Alaska, State of; Aleutian Arc; Aleutian Islands; Coastal and River; Coastal and River Hazards

Publications - PIR 2001-3D | Alaska Division of Geological & Geophysical

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in Shapefile 1.4 M Metadata - Read me Keywords Coastal and River; Coastal and River Hazards; Construction

78 FR 79654 - Vermont: Proposed Authorization of State Hazardous Waste Management Program Revisions

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-31

...EPA proposes to grant final authorization to the State of Vermont for changes to its hazardous waste program. In the ``Rules and Regulations'' section of this Federal Register we are authorizing the changes to the Vermont hazardous waste program under the Resource Conservation and Recovery Act (RCRA) as a direct final rule without prior proposed rule. EPA has determined that these changes satisfy all requirements needed to qualify for final authorization. If we receive no adverse comment, we will not take further action on this proposed rule.

How to HAMMER home hazardous materials training

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ollero, J.

1994-10-01

This article describes HAMMER - the Hazardous Materials Management and Emergency Response Training - program being developed at the Hanford Reservation. The program uses true-to-life props and facilities to simulate emergencies and hazardous conditions. Topics covered include the set-up of the facility and training; the demand for such training; the involvement of the Army Corps of Engineers; the props to be constructed; the educational involvement of Tulane and Xavier Univerisities of Louisiana; temporary facility for the program; partnership with Indian Nations and Stakeholders; and budget plans and constriction. 9 figs.

Construction Management Training in the Navy Seabees

DTIC Science & Technology

1992-01-01

classroom training in developing a variety of skills. Skills attained are recorded under the Personnel Readiness Capability Program (PRCP) and...Functional Skill 090.2) - Hands on safety course required for all crew leaders and project supervisors. e- Hazard Communication (094. 1) - Federal...Hazard Communication Training Program m required by 19CFR1910.1200. This course is required for all personnel. Those exposed to hazardous chemicals

78 FR 43810 - State of Kansas; Authorization of State Hazardous Waste Management Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-22

... seeking authorization for the National Environmental Performance Track Program (April 22, 2004, 69 FR... terminated the National Environmental Performance Track Program. (c) Kansas has not adopted the optional... or more hazardous waste containers are stored, on a monthly basis. (c) At 28-31-262a(f)(2)(B)(i) and...

78 FR 58988 - Louisiana: Final Authorization of State-initiated Changes and Incorporation by Reference of State...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-25

... Waste Management Program AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY... Hazardous Waste Management Programs'', Louisiana's authorized hazardous waste program. The EPA will...), 3006, and 7004(b) of the Solid Waste Disposal Act, as amended, 42 U.S.C. 6912(a), 6926, and 6974(b...

Developing Higher Education Programs in Emergency Management: Ghana's Experience

ERIC Educational Resources Information Center

Yakubu, Mariama Bisongu

2013-01-01

Ghana is highly vulnerable and threatened by several hazards and has sought ways of minimizing impacts of hazards events over time including demonstrating an interest in developing an emergency management training and an higher education degree program. Yet, as of 2013, the country has not developed a disaster management training program or a…

SUPERFUND INNOVATIVE TECHNOLOGY EVALUATION PROGRAM ANNUAL REPORT TO CONGRESS FY2000

EPA Science Inventory

The Superfund Innovative Technology Evaluation Program promotes the development, commercialization, and implementation of innovative hazardous waste treatment technologies. SITE offers a mechanism for conducting joint demonstration and evaluation projects at hazardous waste site...

Rockfall Hazard Process Assessment : Implementation Report

DOT National Transportation Integrated Search

2017-10-01

The Montana Department of Transportation (MDT) commissioned a new research program to improve assessment and management of its rock slope assets. The Department implemented a Rockfall Hazard Rating System (RHRS) program in 2005 and wished to add valu...

THE PENALIZED OPTIMAL EXPERIMENTAL DESIGN: THE PRECISE ESTIMATION OF AN INTERACTION THRESHOLD IN A MIXTURE OF EIGHTEEN POLYHALOGENATED AROMATIC HYDROCARBONS.

EPA Science Inventory

Crofton et al. (EHP, 2005) conducted a study of 18 polyhalogenated aromatic hydrocarbons (PHAHs) on serum total thyroxine (T4). Young female Long-Evans rats were dosed with the 18 single agents or a fixed-ratio mixture, and serum total T4 was measured via radioimmunoassay. The i...

PRESENTED AT TRIANGLE CONSORTIUM OF REPRODUCTIVE BIOLOGY, CHAPEL HILL, NC: GST M1 GENOTYPE INFLUENCES SPERM DNA DAMAGE ASSOCIATED WITH EXPOSURE TO AIR POLLUTION

EPA Science Inventory

Exposure to episodic air pollution in the Czech Republic has been associated with abnormal semen quality and sperm DNA damage (EHP 108:887;2000). A subsequentlongitudinal study evaluated semenfrom 36 men sampled up to 7 times over a period of two years to capture exposures durin...

Engineering risk reduction in satellite programs

NASA Technical Reports Server (NTRS)

Dean, E. S., Jr.

1979-01-01

Methods developed in planning and executing system safety engineering programs for Lockheed satellite integration contracts are presented. These procedures establish the applicable safety design criteria, document design compliance and assess the residual risks where non-compliant design is proposed, and provide for hazard analysis of system level test, handling and launch preparations. Operations hazard analysis identifies product protection and product liability hazards prior to the preparation of operational procedures and provides safety requirements for inclusion in them. The method developed for documenting all residual hazards for the attention of program management assures an acceptable minimum level of risk prior to program deployment. The results are significant for persons responsible for managing or engineering the deployment and production of complex high cost equipment under current product liability law and cost/time constraints, have a responsibility to minimize the possibility of an accident, and should have documentation to provide a defense in a product liability suit.

Perform Thermodynamics Measurements on Fuel Cycle Case Study Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Martin, Leigh R.

This document was prepared to meet FCR&D level 3 milestone M3FT-14IN0304022, “Perform Thermodynamics Measurements on Fuel Cycle Case Study Systems.” This work was carried out under the auspices of the Thermodynamics and Kinetics FCR&D work package. This document reports preliminary work in support of determining the thermodynamic parameters for the ALSEP process. The ALSEP process is a mixed extractant system comprised of a cation exchanger 2-ethylhexyl-phosphonic acid mono-2-ethylhexyl ester (HEH[EHP]) and a neutral solvating extractant N,N,N’,N’-tetraoctyldiglycolamide (TODGA). The extractant combination produces complex organic phase chemistry that is challenging for traditional measurement techniques. To neutralize the complexity, temperature dependent solvent extractionmore » experiments were conducted with neat TODGA and scaled down concentrations of the ALSEP formulation to determine the enthalpies of extraction for the two conditions. A full set of thermodynamic data for Eu, Am, and Cm extraction by TODGA from 3.0 M HNO3 is reported. These data are compared to previous extraction results from a 1.0 M HNO3 aqueous medium, and a short discussion of the mixed HEH[EHP]/TODGA system results is offered.« less

Role of aerosols on the Indian Summer Monsoon variability, as simulated by state-of-the-art global climate models

NASA Astrophysics Data System (ADS)

Cagnazzo, Chiara; Biondi, Riccardo; D'Errico, Miriam; Cherchi, Annalisa; Fierli, Federico; Lau, William K. M.

2016-04-01

Recent observational and modeling analyses have explored the interaction between aerosols and the Indian summer monsoon precipitation on seasonal-to-interannual time scales. By using global scale climate model simulations, we show that when increased aerosol loading is found on the Himalayas slopes in the premonsoon period (April-May), intensification of early monsoon rainfall over India and increased low-level westerly flow follow, in agreement with the elevated-heat-pump (EHP) mechanism. The increase in rainfall during the early monsoon season has a cooling effect on the land surface that may also be amplified through solar dimming (SD) by more cloudiness and aerosol loading with subsequent reduction in monsoon rainfall over India. We extend this analyses to a subset of CMIP5 climate model simulations. Our results suggest that 1) absorbing aerosols, by influencing the seasonal variability of the Indian summer monsoon with the discussed time-lag, may act as a source of predictability for the Indian Summer Monsoon and 2) if the EHP and SD effects are operating also in a number of state-of-the-art climate models, their inclusion could potentially improve seasonal forecasts.

Columnar recombination for X-ray generated electron-holes in amorphous selenium and its significance in a-Se x-ray detectors

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bubon, O.; Thunder Bay Regional Research Institute, Thunder Bay, Ontario, P7A 7T1; Jandieri, K.

Although amorphous selenium (a-Se) has a long and successful history of application in optical and X-ray imaging, some of its fundamental properties are still puzzling. In particularly, the mechanism of carrier recombination following x-ray excitation and electric field and temperature dependences of the electron-hole pair creation energy (W{sub ehp}) remain unclear. Using the combination of X-ray photocurrent and pulse height spectroscopy measurements, we measure W{sub ehp} in a wide range of temperatures (218–320 K) and electric fields (10–100 V/µm) and show that the conventional columnar recombination model which assumes Langevin recombination within a column (a primary electron track) fails to explain experimentalmore » results in a wide range of electric fields and temperatures. The reason for the failure of the conventional model is revealed in this work, and the theory of the columnar recombination is modified to include the saturation of the recombination rate at high electric field in order to account for the experimental results in the entire range of fields and temperatures.« less

Solvent Extraction Separation of Trivalent Americium from Curium and the Lanthanides

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jensen, Mark P.; Chiarizia, Renato; Ulicki, Joseph S.

2015-02-27

The sterically constrained, macrocyclic, aqueous soluble ligand N,N'-bis[(6-carboxy-2-pyridyl)methyl]-1,10-diaza-18-crown-6 (H2BP18C6) was investigated for separating americium from curium and all the lanthanides by solvent extraction. Pairing H2BP18C6, which favors complexation of larger f-element cations, with acidic organophosphorus extractants that favor extraction of smaller f-element cations, such as bis-(2-ethylhexyl)phosphoric acid (HDEHP) or (2-ethylhexyl)phosphonic acid mono(2-ethylhexyl) ester (HEH[EHP]), created solvent extraction systems with good Cm/Am selectivity, excellent trans-lanthanide selectivity (Kex,Lu/Kex,La = 108), but poor selectivity for Am against the lightest lanthanides. However, using an organic phase containing both a neutral extractant, N,N,N’,N’-tetra(2-ethylhexyl)diglycolamide (TEHDGA), and HEH[EHP] enabled rejection of the lightest lanthanides during loading ofmore » the organic phase from aqueous nitric acid, eliminating their interference in the americium stripping stages. In addition, although it is a macrocyclic ligand, H2BP18C6 does not significantly impede the mass transfer kinetics of the HDEHP solvent extraction system« less

Synthesis of hexavalent molybdenum formo- and aceto-hydroxamates and deferoxamine via liquid-liquid metal partitioning

DOE Office of Scientific and Technical Information (OSTI.GOV)

Breshears, Andrew T.; Brown, M. Alex; Bloom, Ira

We report a new method of crystal growth and synthesis based on liquid-liquid partitioning that allows for isolation and in-depth characterization of molybdenyl bis(formohydroxamate), Mo-FHA, molybdenyl bis(acetohydroxamate), Mo-AHA, and molybdenyl deferoxamine, Mo-DFO, for the first time. This novel approach affords shorter crystal growth time (hourly timeframe) without sacrificing crystal size or integrity when other methods of crystallization were unsuccessful. All three Mo complexes are characterized in solution via FTIR, NMR, UV-vis, and EXAFS spectroscopy. Mo-AHA and Mo-FHA structures are resolved by single crystal X-ray diffraction. Using the molybdenyl hydroxamate structural information, the speciation of Mo in a siderophore complex (Mo-DFO)more » is determined via complimentary spectroscopic methods and confirmed by DFT calculations. ESI-MS verifies that a complex of 1:1 molybdenum to deferoxamine is present in solution. Additionally, the Mo solution speciation in the precursor organic phase, MoO2(NO3)2HEH[EHP]2 (where HEH[EHP] is 2-ethylhexylphosphonic acid mono-2-ethylhexyl ester), is characterized by FTIR and EXAFS spectroscopy as well as DFT calculations.« less

75 FR 8042 - Advisory Committee on Earthquake Hazards Reduction Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-23

... Earthquake Hazards Reduction Meeting AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of open meeting. SUMMARY: The Advisory Committee on Earthquake Hazards Reduction.... FOR FURTHER INFORMATION CONTACT: Dr. Jack Hayes, National Earthquake Hazards Reduction Program...

NASA LaRC Hazardous Material Pharmacy

NASA Technical Reports Server (NTRS)

Esquenet, Remy

1995-01-01

In 1993-1994 the Office of Environmental Engineering contracted SAIC to develop NASA Langley's Pollution Prevention (P2) Program. One of the priority projects identified in this contract was the development of a hazardous waste minimization (HAZMIN)/hazardous materials reutilization (HAZMART) program in the form of a Hazardous Materials Pharmacy. A hazardous materials pharmacy is designed to reduce hazardous material procurement costs and hazardous waste disposal costs. This is accomplished through the collection and reissue of excess hazardous material. Currently, a rarely used hazardous material may be stored in a shop area, unused, until it passes its expiration date. The material is then usually disposed of as a hazardous waste, often at a greater expense than the original cost of the material. While this material was on the shelf expiring, other shop areas may have ordered new supplies of the same material. The hazardous material pharmacy would act as a clearinghouse for such materials. Material that is not going to be used would be turned in to the pharmacy. Other users could then be issued this material free of charge, thereby reducing procurement costs. The use of this material by another shop prevents it from expiring, thereby reducing hazardous waste disposal costs.

E-Waste and Harm to Vulnerable Populations: A Growing Global Problem.

PubMed

Heacock, Michelle; Kelly, Carol Bain; Asante, Kwadwo Ansong; Birnbaum, Linda S; Bergman, Åke Lennart; Bruné, Marie-Noel; Buka, Irena; Carpenter, David O; Chen, Aimin; Huo, Xia; Kamel, Mostafa; Landrigan, Philip J; Magalini, Federico; Diaz-Barriga, Fernando; Neira, Maria; Omar, Magdy; Pascale, Antonio; Ruchirawat, Mathuros; Sly, Leith; Sly, Peter D; Van den Berg, Martin; Suk, William A

2016-05-01

Electronic waste (e-waste) is produced in staggering quantities, estimated globally to be 41.8 million tonnes in 2014. Informal e-waste recycling is a source of much-needed income in many low- to middle-income countries. However, its handling and disposal in underdeveloped countries is often unsafe and leads to contaminated environments. Rudimentary and uncontrolled processing methods often result in substantial harmful chemical exposures among vulnerable populations, including women and children. E-waste hazards have not yet received the attention they deserve in research and public health agendas. We provide an overview of the scale and health risks. We review international efforts concerned with environmental hazards, especially affecting children, as a preface to presenting next steps in addressing health issues stemming from the global e-waste problem. The e-waste problem has been building for decades. Increased observation of adverse health effects from e-waste sites calls for protecting human health and the environment from e-waste contamination. Even if e-waste exposure intervention and prevention efforts are implemented, legacy contamination will remain, necessitating increased awareness of e-waste as a major environmental health threat. Global, national, and local levels efforts must aim to create safe recycling operations that consider broad security issues for people who rely on e-waste processing for survival. Paramount to these efforts is reducing pregnant women and children's e-waste exposures to mitigate harmful health effects. With human environmental health in mind, novel dismantling methods and remediation technologies and intervention practices are needed to protect communities. Heacock M, Kelly CB, Asante KA, Birnbaum LS, Bergman AL, Bruné MN, Buka I, Carpenter DO, Chen A, Huo X, Kamel M, Landrigan PJ, Magalini F, Diaz-Barriga F, Neira M, Omar M, Pascale A, Ruchirawat M, Sly L, Sly PD, Van den Berg M, Suk WA. 2016. E-waste and harm to vulnerable populations: a growing global problem. Environ Health Perspect 124:550-555; http://dx.doi.org/10.1289/ehp.1509699.

Polyfluoroalkyl Chemicals and Menopause among Women 20–65 Years of Age (NHANES)

PubMed Central

Hoffman, Kate; Thayer, Kristina A.; Daniels, Julie L.

2013-01-01

Background: Polyfluoroalkyl chemicals (PFCs) such as perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) have been associated with early menopause. However, previous cross-sectional studies have lacked adequate data to investigate possible reverse causality (i.e., higher serum concentrations due to decreased excretion after menopause). Objectives: We investigated the association between PFOS, PFOA, perfluorononanoate (PFNA), and perfluorohexane sulfonate (PFHxS) and age at natural menopause among women 20–65 years of age in NHANES (National Health and Nutrition Examination Survey). Methods: We used proportional hazard models to estimate hazard ratios (HRs) for the onset of natural menopause as a function of age and serum PFC levels, and to investigate reverse causation by estimating associations between PFC levels and the rate of hysterectomy. We also used multivariable linear regression to determine whether time since menopause predicted serum PFC levels. Results: After adjusting for age at survey, race/ethnicity, education, ever smoking, and parity, women with higher levels of PFCs had earlier menopause than did women with the lowest PFC levels. We observed a monotonic association with PFHxS: The HR was 1.42 (95% CI: 1.08, 1.87) for serum concentrations in tertile 2 versus tertile 1, and 1.70 (95% CI: 1.36, 2.12) for tertile 3 versus tertile 1. We also found evidence of reverse causation: PFCs were positively associated with rate of hysterectomy, and time since natural menopause was positively associated with serum PFCs. Conclusions: Our findings suggest a positive association between PFCs and menopause; however, at least part of the association may be due to reverse causation. Regardless of underlying cause, women appear to have higher PFC concentrations after menopause. Citation: Taylor KW, Hoffman K, Thayer KA, Daniels JL. 2014. Polyfluoroalkyl chemicals and menopause among women 20–65 years of age (NHANES). Environ Health Perspect 122:145–150; http://dx.doi.org/10.1289/ehp.1306707 PMID:24280566

Scientific Considerations for Evaluating Cancer Bioassays Conducted by the Ramazzini Institute

PubMed Central

Caldwell, Jane C.; Jinot, Jennifer; Evans, Marina V.; Cote, Ila; Vandenberg, John J.

2013-01-01

Background: The Ramazzini Institute (RI) has completed nearly 400 cancer bioassays on > 200 compounds. The European Food Safety Authority (EFSA) and others have suggested that study design and protocol differences between the RI and other laboratories by may contribute to controversy regarding cancer hazard findings, principally findings on lymphoma/leukemia diagnoses. Objective: We aimed to evaluate RI study design, protocol differences, and accuracy of tumor diagnoses for their impact on carcinogenic hazard characterization. Methods: We analyzed the findings from a recent Pathology Working Group (PWG) review of RI procedures and tumor diagnoses, evaluated consistency of RI and other laboratory findings for chemicals identified by the RI as positive for lymphoma/leukemia, and examined evidence for a number of other issues raised regarding RI bioassays. The RI cancer bioassay design and protocols were evaluated in the context of relevant risk assessment guidance from international authorities. Discussion: Although the PWG identified close agreement with RI diagnoses for most tumor types, it did not find close agreement for lymphoma/leukemia of the respiratory tract or for neoplasms of the inner ear and cranium. Here we discuss a) the implications of the PWG findings, particularly lymphoma diagnostic issues; b) differences between RI studies and those from other laboratories that are relevant to evaluating RI cancer bioassays; and c) future work that may help resolve some concerns. Conclusions: We concluded that a) issues related to respiratory tract infections have complicated diagnoses at that site (i.e., lymphoma/leukemia), as well as for neoplasms of the inner ear and cranium, and b) there is consistency and value in RI studies for identification of other chemical-related neoplasia. Citation: Gift JS, Caldwell JC, Jinot J, Evans MV, Cote I, Vandenberg JJ. 2013. Scientific considerations for evaluating cancer bioassays conducted by the Ramazzini Institute. Environ Health Perspect 121:1253–1263; http://dx.doi.org/10.1289/ehp.1306661 PMID:24045135

Ambient Air Pollution and Cancer Mortality in the Cancer Prevention Study II

PubMed Central

Krewski, Daniel; Diver, W. Ryan; Pope, C. Arden; Burnett, Richard T.; Jerrett, Michael; Marshall, Julian D.; Gapstur, Susan M.

2017-01-01

Background: The International Agency for Research on Cancer classified both outdoor air pollution and airborne particulate matter as carcinogenic to humans (Group 1) for lung cancer. There may be associations with cancer at other sites; however, the epidemiological evidence is limited. Objective: The aim of this study was to clarify whether ambient air pollution is associated with specific types of cancer other than lung cancer by examining associations of ambient air pollution with nonlung cancer death in the Cancer Prevention Study II (CPS-II). Methods: Analysis included 623,048 CPS-II participants who were followed for 22 y (1982–2004). Modeled estimates of particulate matter with aerodynamic diameter <2.5µm (PM2.5) (1999–2004), nitrogen dioxide (NO2) (2006), and ozone (O3) (2002–2004) concentrations were linked to the participant residence at enrollment. Cox proportional hazards models were used to estimate associations per each fifth percentile–mean increment with cancer mortality at 29 anatomic sites, adjusted for individual and ecological covariates. Results: We observed 43,320 nonlung cancer deaths. PM2.5 was significantly positively associated with death from cancers of the kidney {adjusted hazard ratio (HR) per 4.4 μg/m3=1.14 [95% confidence interval (CI): 1.03, 1.27]} and bladder [HR=1.13 (95% CI: 1.03, 1.23)]. NO2 was positively associated with colorectal cancer mortality [HR per 6.5 ppb=1.06 (95% CI: 1.02, 1.10). The results were similar in two-pollutant models including PM2.5 and NO2 and in three-pollutant models with O3. We observed no statistically significant positive associations with death from other types of cancer based on results from adjusted models. Conclusions: The results from this large prospective study suggest that ambient air pollution was not associated with death from most nonlung cancers, but associations with kidney, bladder, and colorectal cancer death warrant further investigation. https://doi.org/10.1289/EHP1249 PMID:28886601

Individual and Neighborhood Socioeconomic Status and the Association between Air Pollution and Cardiovascular Disease.

PubMed

Chi, Gloria C; Hajat, Anjum; Bird, Chloe E; Cullen, Mark R; Griffin, Beth Ann; Miller, Kristin A; Shih, Regina A; Stefanick, Marcia L; Vedal, Sverre; Whitsel, Eric A; Kaufman, Joel D

2016-12-01

Long-term fine particulate matter (PM2.5) exposure is linked with cardiovascular disease, and disadvantaged status may increase susceptibility to air pollution-related health effects. In addition, there are concerns that this association may be partially explained by confounding by socioeconomic status (SES). We examined the roles that individual- and neighborhood-level SES (NSES) play in the association between PM2.5 exposure and cardiovascular disease. The study population comprised 51,754 postmenopausal women from the Women's Health Initiative Observational Study. PM2.5 concentrations were predicted at participant residences using fine-scale regionalized universal kriging models. We assessed individual-level SES and NSES (Census-tract level) across several SES domains including education, occupation, and income/wealth, as well as through an NSES score, which captures several important dimensions of SES. Cox proportional-hazards regression adjusted for SES factors and other covariates to determine the risk of a first cardiovascular event. A 5 μg/m3 higher exposure to PM2.5 was associated with a 13% increased risk of cardiovascular event [hazard ratio (HR) 1.13; 95% confidence interval (CI): 1.02, 1.26]. Adjustment for SES factors did not meaningfully affect the risk estimate. Higher risk estimates were observed among participants living in low-SES neighborhoods. The most and least disadvantaged quartiles of the NSES score had HRs of 1.39 (95% CI: 1.21, 1.61) and 0.90 (95% CI: 0.72, 1.07), respectively. Women with lower NSES may be more susceptible to air pollution-related health effects. The association between air pollution and cardiovascular disease was not explained by confounding from individual-level SES or NSES. Citation: Chi GC, Hajat A, Bird CE, Cullen MR, Griffin BA, Miller KA, Shih RA, Stefanick ML, Vedal S, Whitsel EA, Kaufman JD. 2016. Individual and neighborhood socioeconomic status and the association between air pollution and cardiovascular disease. Environ Health Perspect 124:1840-1847; http://dx.doi.org/10.1289/EHP199.

Mitochondria, Energetics, Epigenetics, and Cellular Responses to Stress

PubMed Central

McAllister, Kimberly; Worth, Leroy; Haugen, Astrid C.; Meyer, Joel N.; Domann, Frederick E.; Van Houten, Bennett; Mostoslavsky, Raul; Bultman, Scott J.; Baccarelli, Andrea A.; Begley, Thomas J.; Sobol, Robert W.; Hirschey, Matthew D.; Ideker, Trey; Santos, Janine H.; Copeland, William C.; Tice, Raymond R.; Balshaw, David M.; Tyson, Frederick L.

2014-01-01

Background: Cells respond to environmental stressors through several key pathways, including response to reactive oxygen species (ROS), nutrient and ATP sensing, DNA damage response (DDR), and epigenetic alterations. Mitochondria play a central role in these pathways not only through energetics and ATP production but also through metabolites generated in the tricarboxylic acid cycle, as well as mitochondria–nuclear signaling related to mitochondria morphology, biogenesis, fission/fusion, mitophagy, apoptosis, and epigenetic regulation. Objectives: We investigated the concept of bidirectional interactions between mitochondria and cellular pathways in response to environmental stress with a focus on epigenetic regulation, and we examined DNA repair and DDR pathways as examples of biological processes that respond to exogenous insults through changes in homeostasis and altered mitochondrial function. Methods: The National Institute of Environmental Health Sciences sponsored the Workshop on Mitochondria, Energetics, Epigenetics, Environment, and DNA Damage Response on 25–26 March 2013. Here, we summarize key points and ideas emerging from this meeting. Discussion: A more comprehensive understanding of signaling mechanisms (cross-talk) between the mitochondria and nucleus is central to elucidating the integration of mitochondrial functions with other cellular response pathways in modulating the effects of environmental agents. Recent studies have highlighted the importance of mitochondrial functions in epigenetic regulation and DDR with environmental stress. Development and application of novel technologies, enhanced experimental models, and a systems-type research approach will help to discern how environmentally induced mitochondrial dysfunction affects key mechanistic pathways. Conclusions: Understanding mitochondria–cell signaling will provide insight into individual responses to environmental hazards, improving prediction of hazard and susceptibility to environmental stressors. Citation: Shaughnessy DT, McAllister K, Worth L, Haugen AC, Meyer JN, Domann FE, Van Houten B, Mostoslavsky R, Bultman SJ, Baccarelli AA, Begley TJ, Sobol RW, Hirschey MD, Ideker T, Santos JH, Copeland WC, Tice RR, Balshaw DM, Tyson FL. 2014. Mitochondria, energetics, epigenetics, and cellular responses to stress. Environ Health Perspect 122:1271–1278; http://dx.doi.org/10.1289/ehp.1408418 PMID:25127496

40 CFR 271.4 - Consistency.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) REQUIREMENTS FOR AUTHORIZATION OF STATE HAZARDOUS WASTE PROGRAMS Requirements for Final Authorization § 271.4... hazardous waste programs which have received final authorization under this part. (a) Any aspect of the...

40 CFR 271.4 - Consistency.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) REQUIREMENTS FOR AUTHORIZATION OF STATE HAZARDOUS WASTE PROGRAMS Requirements for Final Authorization § 271.4... hazardous waste programs which have received final authorization under this part. (a) Any aspect of the...

40 CFR 271.4 - Consistency.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) REQUIREMENTS FOR AUTHORIZATION OF STATE HAZARDOUS WASTE PROGRAMS Requirements for Final Authorization § 271.4... hazardous waste programs which have received final authorization under this part. (a) Any aspect of the...

RMP Guidance for Warehouses - Chapter 7: Prevention Program (Program 3)

EPA Pesticide Factsheets

If you are already complying with the OSHA Process Safety Management standard for on-site consequences, your process hazard analysis (PHA) team may have to assess new hazards that could affect the public or the environment offsite.

77 FR 15453 - Pipeline Safety: Information Collection Activities

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-15

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket No... information collection titled, ``Gas Pipeline Safety Program Certification and Hazardous Liquid Pipeline... collection request that PHMSA will be submitting to OMB for renewal titled, ``Gas Pipeline Safety Program...

40 CFR 264.271 - Treatment program.

Code of Federal Regulations, 2013 CFR

2013-07-01

....271 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land... land treatment program that is designed to ensure that hazardous constituents placed in or on the...

40 CFR 264.271 - Treatment program.

Code of Federal Regulations, 2010 CFR

2010-07-01

....271 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land... land treatment program that is designed to ensure that hazardous constituents placed in or on the...

40 CFR 264.271 - Treatment program.

Code of Federal Regulations, 2014 CFR

2014-07-01

....271 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land... land treatment program that is designed to ensure that hazardous constituents placed in or on the...

40 CFR 264.271 - Treatment program.

Code of Federal Regulations, 2011 CFR

2011-07-01

....271 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land... land treatment program that is designed to ensure that hazardous constituents placed in or on the...

40 CFR 264.271 - Treatment program.

Code of Federal Regulations, 2012 CFR

2012-07-01

....271 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land... land treatment program that is designed to ensure that hazardous constituents placed in or on the...

Remote Excavation of Heavily Contaminated UXO Sites. The Range Master

DTIC Science & Technology

2007-09-05

NUMBER 5c. PROGRAM ELEMENT NUMBER 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 6. AUTHOR(S) 7. PERFORMING ORGANIZATION NAME(S) AND...Master) ESTCP Project UX-200327 ii Final Phase II Report, September 2007 3.5.5 Sampling Plan...Explosive HSP Health and Safety Program HTRW Hazardous, Toxic, and Radioactive Waste HTW Hazardous and Toxic Waste HW Hazardous Waste IAW In

Department of Defense Federal Hazard Communication Training Program

DTIC Science & Technology

1988-04-01

APPLICATION EXERCISE 3A-2 Continued Marilyn works as a supervisor in a plant that uses ammonium nitrate to make gun powder and blasting agents. 3) What...Dimethyl Freehold Products East Base Shop Polysiloxane Maintenance Shop Light Hydraulic Oil Texas Oil Co. Plant Maintenance C-2 Product Name Manufacturer Use ...Defense Federal Hazard Communication Training Program, Student Workbook," when used with "Department of Defense Federal Hazard Communication Training

A Review of Hazard Anticipation Training Programs for Young Drivers

PubMed Central

McDonald, Catherine C.; Goodwin, Arthur H.; Pradhan, Anuj K.; Romoser, Matthew R.E.; Williams, Allan F.

2015-01-01

Purpose Poor hazard anticipation skills are a risk factor associated with high motor vehicle crash rates of young drivers. A number of programs have been developed to improve these skills. The purpose of this review was to assess the empirical literature on hazard anticipation training for young drivers. Methods Studies were included if they: 1) included an assessment of hazard anticipation training outcomes; 2) were published between January 1, 1980 and December 31, 2013 in an English language peer-reviewed journal or conference proceeding; and 3) included at least one group that uniquely comprised a cohort of participants <21 years. Nineteen studies met inclusion criteria. Results Studies used a variety of training methods including interactive computer programs, videos, simulation, commentary driving, or a combination of approaches. Training effects were predominantly measured through computer-based testing and driving simulation with eye tracking. Four studies included an on-road evaluation. Most studies evaluated short-term outcomes (immediate or few days). In all studies, young drivers showed improvement in selected hazard anticipation outcomes, but none investigated crash effects. Conclusions Although there is promise in existing programs, future research should include long-term follow up, evaluate crash outcomes, and assess the optimal timing of hazard anticipation training taking into account the age and experience level of young drivers. PMID:26112734

40 CFR 271.10 - Requirements for generators of hazardous wastes.

Code of Federal Regulations, 2012 CFR

2012-07-01

... hazardous wastes. 271.10 Section 271.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) REQUIREMENTS FOR AUTHORIZATION OF STATE HAZARDOUS WASTE PROGRAMS Requirements for Final Authorization § 271.10 Requirements for generators of hazardous wastes. (a) The State...

40 CFR 271.11 - Requirements for transporters of hazardous wastes.

Code of Federal Regulations, 2012 CFR

2012-07-01

... hazardous wastes. 271.11 Section 271.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) REQUIREMENTS FOR AUTHORIZATION OF STATE HAZARDOUS WASTE PROGRAMS Requirements for Final Authorization § 271.11 Requirements for transporters of hazardous wastes. (a) The State...

40 CFR 271.11 - Requirements for transporters of hazardous wastes.

Code of Federal Regulations, 2013 CFR

2013-07-01

... hazardous wastes. 271.11 Section 271.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) REQUIREMENTS FOR AUTHORIZATION OF STATE HAZARDOUS WASTE PROGRAMS Requirements for Final Authorization § 271.11 Requirements for transporters of hazardous wastes. (a) The State...

40 CFR 271.10 - Requirements for generators of hazardous wastes.

Code of Federal Regulations, 2013 CFR

2013-07-01

... hazardous wastes. 271.10 Section 271.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) REQUIREMENTS FOR AUTHORIZATION OF STATE HAZARDOUS WASTE PROGRAMS Requirements for Final Authorization § 271.10 Requirements for generators of hazardous wastes. (a) The State...

40 CFR 271.10 - Requirements for generators of hazardous wastes.

Code of Federal Regulations, 2011 CFR

2011-07-01

... hazardous wastes. 271.10 Section 271.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) REQUIREMENTS FOR AUTHORIZATION OF STATE HAZARDOUS WASTE PROGRAMS Requirements for Final Authorization § 271.10 Requirements for generators of hazardous wastes. (a) The State...

14 CFR 135.503 - Hazardous materials training: General.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Hazardous materials training: General. 135.503 Section 135.503 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.503 Hazardous materials training: General. (a) Each certificate...

14 CFR 135.507 - Hazardous materials training records.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Hazardous materials training records. 135.507 Section 135.507 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.507 Hazardous materials training records. (a) General requirement...

14 CFR 135.505 - Hazardous materials training required.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Hazardous materials training required. 135.505 Section 135.505 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.505 Hazardous materials training required. (a) Training...

14 CFR 135.507 - Hazardous materials training records.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Hazardous materials training records. 135.507 Section 135.507 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.507 Hazardous materials training records. (a) General requirement...

14 CFR 135.505 - Hazardous materials training required.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Hazardous materials training required. 135.505 Section 135.505 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.505 Hazardous materials training required. (a) Training...

14 CFR 135.503 - Hazardous materials training: General.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Hazardous materials training: General. 135.503 Section 135.503 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.503 Hazardous materials training: General. (a) Each certificate...

14 CFR 135.503 - Hazardous materials training: General.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Hazardous materials training: General. 135.503 Section 135.503 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.503 Hazardous materials training: General. (a) Each certificate...

14 CFR 135.503 - Hazardous materials training: General.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Hazardous materials training: General. 135.503 Section 135.503 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.503 Hazardous materials training: General. (a) Each certificate...

14 CFR 135.505 - Hazardous materials training required.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Hazardous materials training required. 135.505 Section 135.505 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.505 Hazardous materials training required. (a) Training...

14 CFR 135.507 - Hazardous materials training records.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Hazardous materials training records. 135.507 Section 135.507 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.507 Hazardous materials training records. (a) General requirement...

14 CFR 135.505 - Hazardous materials training required.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Hazardous materials training required. 135.505 Section 135.505 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.505 Hazardous materials training required. (a) Training...

14 CFR 135.505 - Hazardous materials training required.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Hazardous materials training required. 135.505 Section 135.505 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.505 Hazardous materials training required. (a) Training...

14 CFR 135.503 - Hazardous materials training: General.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Hazardous materials training: General. 135.503 Section 135.503 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.503 Hazardous materials training: General. (a) Each certificate...

14 CFR 135.507 - Hazardous materials training records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Hazardous materials training records. 135.507 Section 135.507 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.507 Hazardous materials training records. (a) General requirement...

14 CFR 135.507 - Hazardous materials training records.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Hazardous materials training records. 135.507 Section 135.507 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Hazardous Materials Training Program § 135.507 Hazardous materials training records. (a) General requirement...

77 FR 19224 - Advisory Committee on Earthquake Hazards Reduction Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-30

... Earthquake Hazards Reduction Meeting AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of open meeting. SUMMARY: The Advisory Committee on Earthquake Hazards Reduction... should be sent to National Earthquake Hazards Reduction Program Director, National Institute of Standards...

77 FR 27439 - Advisory Committee on Earthquake Hazards Reduction Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-10

... Earthquake Hazards Reduction Meeting AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of open meeting. SUMMARY: The Advisory Committee on Earthquake Hazards Reduction... should be sent to National Earthquake Hazards Reduction Program Director, National Institute of Standards...

75 FR 75457 - Advisory Committee on Earthquake Hazards Reduction Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-03

... Earthquake Hazards Reduction Meeting AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of open meeting. SUMMARY: The Advisory Committee on Earthquake Hazards Reduction... meeting should be sent to National Earthquake Hazards Reduction Program Director, National Institute of...

76 FR 72905 - Advisory Committee on Earthquake Hazards Reduction Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-28

... Earthquake Hazards Reduction Meeting AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of open meeting. SUMMARY: The Advisory Committee on Earthquake Hazards Reduction.... ADDRESSES: Questions regarding the meeting should be sent to National Earthquake Hazards Reduction Program...

76 FR 8712 - Advisory Committee on Earthquake Hazards Reduction Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-15

... Earthquake Hazards Reduction Meeting AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of open meeting. SUMMARY: The Advisory Committee on Earthquake Hazards Reduction... Committee's 2011 Annual Report of the Effectiveness of the National Earthquake Hazards Reduction Program...

77 FR 18792 - Advisory Committee on Earthquake Hazards Reduction Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-28

... Earthquake Hazards Reduction Meeting AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of open meeting. SUMMARY: The Advisory Committee on Earthquake Hazards Reduction... should be sent to National Earthquake Hazards Reduction Program Director, National Institute of Standards...

75 FR 18787 - Advisory Committee on Earthquake Hazards Reduction Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-13

... Earthquake Hazards Reduction Meeting AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of open meeting. SUMMARY: The Advisory Committee on Earthquake Hazards Reduction... sent to National Earthquake Hazards Reduction Program Director, National Institute of Standards and...

2013 Los Alamos National Laboratory Hazardous Waste Minimization Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Salzman, Sonja L.; English, Charles J.

2015-08-24

Waste minimization and pollution prevention are inherent goals within the operating procedures of Los Alamos National Security, LLC (LANS). The US Department of Energy (DOE) and LANS are required to submit an annual hazardous waste minimization report to the New Mexico Environment Department (NMED) in accordance with the Los Alamos National Laboratory (LANL or the Laboratory) Hazardous Waste Facility Permit. The report was prepared pursuant to the requirements of Section 2.9 of the LANL Hazardous Waste Facility Permit. This report describes the hazardous waste minimization program (a component of the overall Waste Minimization/Pollution Prevention [WMin/PP] Program) administered by the Environmentalmore » Stewardship Group (ENV-ES). This report also supports the waste minimization and pollution prevention goals of the Environmental Programs Directorate (EP) organizations that are responsible for implementing remediation activities and describes its programs to incorporate waste reduction practices into remediation activities and procedures. LANS was very successful in fiscal year (FY) 2013 (October 1-September 30) in WMin/PP efforts. Staff funded four projects specifically related to reduction of waste with hazardous constituents, and LANS won four national awards for pollution prevention efforts from the National Nuclear Security Administration (NNSA). In FY13, there was no hazardous, mixedtransuranic (MTRU), or mixed low-level (MLLW) remediation waste generated at the Laboratory. More hazardous waste, MTRU waste, and MLLW was generated in FY13 than in FY12, and the majority of the increase was related to MTRU processing or lab cleanouts. These accomplishments and analysis of the waste streams are discussed in much more detail within this report.« less

Geohazards Graduate Study With the U.S. Peace Corps

NASA Astrophysics Data System (ADS)

Rose, William I.; Bluth, Gregg J. S.

A unique, new educational program that focuses on geological natural hazards, U.S. Peace Corps field work, and on-campus study has begun its second year at Michigan Technological University, in Houghton, Michigan.While “Masters International” programs that combine Peace Corps service with a graduate degree program are available at 49 different universities in a variety of fields, the program at Michigan Tech is the only one with a natural hazards focus offering geological degree programs.

Highway Safety Program Manual: Volume 16: Debris Hazard Control and Cleanup.

ERIC Educational Resources Information Center

National Highway Traffic Safety Administration (DOT), Washington, DC.

Volume 16 of the 19-volume Highway Safety Program Manual (which provides guidance to State and local governments on preferred highway safety practices) concentrates on debris hazard control and cleanup. The purpose and objectives of such a program are outlined. Federal authority in the area of highway safety and policies regarding a debris control…

LABORATORY AND FIELD AUDITS AS PART OF THE EPA (ENVIRONMENTAL PROTECTION AGENCY) HAZARDOUS WASTE ENGINEERING RESEARCH LABORATORY (HWERL) QUALITY ASSURANCE PROGRAM

EPA Science Inventory

Audits are an important and integral part of the EPA Hazardous Waste Engineering Research Laboratory (HWERL) Quality Assurance (QA) Program. As part of the overall QA program, audits are used to determine contractor compliance with quality assurance plans and to assess the overal...

Identification and Validation of Agricultural Hazardous Occupations Order Certification Program Instructor Criteria and Competencies

ERIC Educational Resources Information Center

Snyder, Shannon; French, Brian; Field, William; Tormoehlen, Roger; Ess, Daniel

2013-01-01

The USDA/NIFA has awarded funding to Land Grant Institutions to conduct and enhance the Hazardous Occupations Safety Training in Agriculture (HOSTA) program. The HOSTA program is designed to provide relevant educational opportunities in an effort to reduce the frequency and severity of farm-related injuries to all youth who work in agricultural…

SUPERFUND INNOVATIVE TECHNOLOGY EVALUATION PROGRAM: TECHNOLOGY WITH AN IMPACT

EPA Science Inventory

SITE promotes the development and implementation of innovative technologies for remediating hazardous waste sites and for evaluating the nature and extent of hazardous waste site contamination through four component segments. The SITE Program is a key element in EPA's efforts...

40 CFR 68.67 - Process hazard analysis.

Code of Federal Regulations, 2011 CFR

2011-07-01

...) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.67 Process hazard analysis. (a... potential for catastrophic consequences. (3) Engineering and administrative controls applicable to the... engineering and administrative controls; (5) Stationary source siting; (6) Human factors; and (7) A...

40 CFR 68.67 - Process hazard analysis.

Code of Federal Regulations, 2012 CFR

2012-07-01

...) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.67 Process hazard analysis. (a... potential for catastrophic consequences. (3) Engineering and administrative controls applicable to the... engineering and administrative controls; (5) Stationary source siting; (6) Human factors; and (7) A...

40 CFR 68.67 - Process hazard analysis.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) CHEMICAL ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.67 Process hazard analysis. (a... potential for catastrophic consequences. (3) Engineering and administrative controls applicable to the... engineering and administrative controls; (5) Stationary source siting; (6) Human factors; and (7) A...

40 CFR 146.61 - Applicability

Code of Federal Regulations, 2010 CFR

2010-07-01

... INJECTION CONTROL PROGRAM: CRITERIA AND STANDARDS Criteria and Standards Applicable to Class I Hazardous Waste Injection Wells § 146.61 Applicability (a) This subpart establishes criteria and standards for underground injection control programs to regulate Class I hazardous waste injection wells. Unless otherwise...

40 CFR 272.1300 - State authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 272.1300 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Missouri § 272.1300 State authorization. (a) The State of Missouri is authorized to administer and enforce a hazardous waste management program in lieu of...

Publications of the Volcano Hazards Program 2011

USGS Publications Warehouse

Nathenson, Manuel

2013-01-01

The Volcano Hazards Program of the U.S. Geological Survey (USGS) is part of the Geologic Hazards Assessments subactivity, as funded by Congressional appropriation. Investigations are carried out by the USGS and with cooperators at the Alaska Division of Geological and Geophysical Surveys, University of Alaska Fairbanks Geophysical Institute, University of Hawaii Manoa and Hilo, University of Utah, and University of Washington Geophysics Program. This report lists publications from all these institutions. Only published papers and maps are included here; abstracts presented at scientific meetings are omitted. Publication dates are based on year of issue, with no attempt to assign them to fiscal year.

75 FR 5258 - Hazardous Materials Transportation; Registration and Fee Assessment Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-02

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part 107 [Docket No. PHMSA-2009-0201 (HM-208H)] RIN 2137-AE47 Hazardous Materials Transportation... transportation, certain categories and quantities of hazardous materials. PHMSA's proposal would provide that...

40 CFR Table 8 to Subpart Ffff of... - Soluble Hazardous Air Pollutants

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 14 2013-07-01 2013-07-01 false Soluble Hazardous Air Pollutants 8...) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Miscellaneous Coating...

40 CFR Table 8 to Subpart Ffff of... - Soluble Hazardous Air Pollutants

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 14 2014-07-01 2014-07-01 false Soluble Hazardous Air Pollutants 8...) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Miscellaneous Coating...

40 CFR Table 9 to Subpart Ffff of... - Soluble Hazardous Air Pollutants

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 13 2014-07-01 2014-07-01 false Soluble Hazardous Air Pollutants 9...) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Miscellaneous Organic...

40 CFR Table 16 to Subpart Xxxx of... - Selected Hazardous Air Pollutants

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 13 2012-07-01 2012-07-01 false Selected Hazardous Air Pollutants 16...) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emissions Standards for Hazardous Air Pollutants: Rubber Tire Manufacturing...

40 CFR Table 8 to Subpart Ffff of... - Soluble Hazardous Air Pollutants

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 14 2012-07-01 2011-07-01 true Soluble Hazardous Air Pollutants 8...) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Miscellaneous Coating...

40 CFR Table 16 to Subpart Xxxx of... - Selected Hazardous Air Pollutants

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 13 2014-07-01 2014-07-01 false Selected Hazardous Air Pollutants 16...) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emissions Standards for Hazardous Air Pollutants: Rubber Tire Manufacturing...

40 CFR 271.11 - Requirements for transporters of hazardous wastes.

Code of Federal Regulations, 2010 CFR

2010-07-01

... that such wastes do not present a hazard to human health or the environment. These requirements shall... hazardous wastes. 271.11 Section 271.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) REQUIREMENTS FOR AUTHORIZATION OF STATE HAZARDOUS WASTE PROGRAMS Requirements...

40 CFR 271.11 - Requirements for transporters of hazardous wastes.

Code of Federal Regulations, 2014 CFR

2014-07-01

... that such wastes do not present a hazard to human health or the environment. These requirements shall... hazardous wastes. 271.11 Section 271.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) REQUIREMENTS FOR AUTHORIZATION OF STATE HAZARDOUS WASTE PROGRAMS Requirements...

40 CFR 271.11 - Requirements for transporters of hazardous wastes.

Code of Federal Regulations, 2011 CFR

2011-07-01

... that such wastes do not present a hazard to human health or the environment. These requirements shall... hazardous wastes. 271.11 Section 271.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) REQUIREMENTS FOR AUTHORIZATION OF STATE HAZARDOUS WASTE PROGRAMS Requirements...

40 CFR Table 16 to Subpart Xxxx of... - Selected Hazardous Air Pollutants

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 13 2013-07-01 2012-07-01 true Selected Hazardous Air Pollutants 16...) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emissions Standards for Hazardous Air Pollutants: Rubber Tire Manufacturing...

40 CFR Table 9 to Subpart Ffff of... - Soluble Hazardous Air Pollutants

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 13 2013-07-01 2012-07-01 true Soluble Hazardous Air Pollutants 9...) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Miscellaneous Organic...

40 CFR Table 8 to Subpart Ffff of... - Soluble Hazardous Air Pollutants

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 13 2011-07-01 2011-07-01 false Soluble Hazardous Air Pollutants 8...) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES (CONTINUED) National Emission Standards for Hazardous Air Pollutants: Miscellaneous Coating...

78 FR 8109 - Advisory Committee on Earthquake Hazards Reduction Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-05

... Earthquake Hazards Reduction Meeting AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of open meeting. SUMMARY: The Advisory Committee on Earthquake Hazards Reduction... meeting on the National Earthquake Hazards Reduction Program (NEHRP) web site at http://nehrp.gov...

77 FR 75610 - Advisory Committee on Earthquake Hazards Reduction Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-21

... Earthquake Hazards Reduction Meeting AGENCY: National Institute of Standards and Technology, Department of Commerce. ACTION: Notice of open meeting. SUMMARY: The Advisory Committee on Earthquake Hazards Reduction... meeting on the National Earthquake Hazards Reduction Program (NEHRP) Web site at http://nehrp.gov...

75 FR 60398 - California: Proposed Authorization of State Hazardous Waste Management Program Revision

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-30

...) Hazardous Soils Treatment Standards and Exclusions; (8) Administrative Stay for Zinc Micronutrient... Hazardous Wastes from Carbamate Production; (10) Extension of Compliance Date for Characteristic Slags; (11...

Progress in NTHMP Hazard Assessment

USGS Publications Warehouse

Gonzalez, F.I.; Titov, V.V.; Mofjeld, H.O.; Venturato, A.J.; Simmons, R.S.; Hansen, R.; Combellick, Rodney; Eisner, R.K.; Hoirup, D.F.; Yanagi, B.S.; Yong, S.; Darienzo, M.; Priest, G.R.; Crawford, G.L.; Walsh, T.J.

2005-01-01

The Hazard Assessment component of the U.S. National Tsunami Hazard Mitigation Program has completed 22 modeling efforts covering 113 coastal communities with an estimated population of 1.2 million residents that are at risk. Twenty-three evacuation maps have also been completed. Important improvements in organizational structure have been made with the addition of two State geotechnical agency representatives to Steering Group membership, and progress has been made on other improvements suggested by program reviewers. ?? Springer 2005.

Environmental Assessment for Management of South End of Runway Wetlands, Moody AFB, Georgia

DTIC Science & Technology

2010-11-01

implement a management program for the wetlands at the south end of runway (EOR) at Moody AFB to reduce the bird/wildlife aircraft strike hazard (BASH) risk...because birds and other wildlife pose an increased bird/wildlife aircraft strike hazard (BASH) risk to aircraft utilizing the Moody AFB airfield. ln...support ofthe military mission, Moody AFB has implemented a BASH management program designed to minimize aircraft exposure to potentially hazardous

Medical University of South Carolina Environmental Hazards Assessment Program. Deliverables: Volume 3, Annual report, July 1, 1993--June 30, 1994

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1994-08-18

This reference is concerned with the Crossroads of Humanity workshop which is part of the Environmental Hazards Assessment Program at the Medical University of South Carolina. This workshop was held during the month of June and July 1994. Topics discussed include: Perceived Risk Advisory Committee Meeting, surveys of public opinion about hazardous and radioactive materials, genetics,antibodies, and regulatory agencies.

40 CFR Table 16 to Subpart Xxxx of... - Selected Hazardous Air Pollutants

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 12 2010-07-01 2010-07-01 true Selected Hazardous Air Pollutants 16...) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES National Emissions Standards for Hazardous Air Pollutants: Rubber Tire Manufacturing Pt. 63, Subpt...

40 CFR 373.4 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... COMMUNITY RIGHT-TO-KNOW PROGRAMS REPORTING HAZARDOUS SUBSTANCE ACTIVITY WHEN SELLING OR TRANSFERRING FEDERAL... definitions apply: (a) Hazardous substances means that group of substances defined as hazardous under CERCLA 101(14), and that appear at 40 CFR 302.4. (b) Storage means the holding of hazardous substances for a...

Informing Workers of Chemical Hazards: The OSHA Hazard Communication Standard.

ERIC Educational Resources Information Center

American Chemical Society, Washington, DC.

Practical information on how to implement a chemical-related safety program is outlined in this publication. Highlights of the federal Occupational Safety and Health Administrations (OSHA) Hazard Communication Standard are presented and explained. These include: (1) hazard communication requirements (consisting of warning labels, material safety…

77 FR 37898 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-25

... Activities; Submission to OMB for Review and Approval; Comment Request; Hazardous Remediation Waste....regulations.gov . Title: Hazardous Remediation Waste Management Requirements (HWIR- Media) (Renewal). ICR... program), EPA regulates newly generated hazardous wastes, as well as hazardous remediation wastes (i.e...

78 FR 15735 - Agency Information Collection Activities: Proposed Collection; Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-12

... 1995, this notice seeks comments concerning the Hazard Mitigation Grant Program application and... CONTACT: Cecelia Rosenberg, Chief, Grants Policy Branch, Mitigation Division, (202) 646-3321. You may.... 5170c, established the Hazard Mitigation Grant Program. Grant requirements and grants management...

40 CFR 272.700 - State authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 272.700 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Illinois § 272.700 State authorization. (a) The State of Illinois is authorized to administer and enforce a hazardous waste management program in lieu of the...

40 CFR 272.1800 - State authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 272.1800 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Ohio § 272.1800 State authorization. (a) The State of Ohio is authorized to administer and enforce a hazardous waste management program in lieu of the...

40 CFR 272.400 - State authorization.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 272.400 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Delaware § 272.400 State authorization. (a) The State of Delaware is authorized to administer and enforce a hazardous waste management program in lieu of the...

29 CFR 1960.41 - National committee duties.

Code of Federal Regulations, 2010 CFR

2010-07-01

... plans for abating hazards; and responses to reports of hazardous conditions; safety and health program... report of hazardous working conditions. ... Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR...

Hazardous Waste: Cleanup and Prevention.

ERIC Educational Resources Information Center

Vandas, Steve; Cronin, Nancy L.

1996-01-01

Describes the Superfund, a federal cleanup program created in response to growing public concern over the health and environmental risks posed by hazardous waste sites. Discusses sources, disposal, and movement and risk of hazardous waste. (JRH)

Publications - MP 158 | Alaska Division of Geological & Geophysical Surveys

Science.gov Websites

Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in Alaska Deposits; Bluff; Coastal; Coastal Erosion; Depositional Environment; Dunes; Engineering Geology; Flood

Publications - IC 44 ed. 2004 | Alaska Division of Geological & Geophysical

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in Map; Aeromagnetic Survey; Airborne Geophysical Survey; Alaska, State of; Bibliography; Coastal and

Publications - DDS 10 | Alaska Division of Geological & Geophysical Surveys

Science.gov Websites

Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in Alaska Products Interactive Interactive Map Alaska Tsunami Inundation Maps Keywords Coastal and River; Geologic

Long-term moderate wind induced sediment resuspension meeting phosphorus demand of phytoplankton in the large shallow eutrophic Lake Taihu.

PubMed

Chao, Jian-Ying; Zhang, Yi-Min; Kong, Ming; Zhuang, Wei; Wang, Long-Mian; Shao, Ke-Qiang; Gao, Guang

2017-01-01

The objective of this study was to investigate the impact of sediment resuspension and phosphorus (P) release on phytoplankton growth under different kinds of wind-wave disturbance conditions in the large and shallow eutrophic Lake Taihu in China. Short-term strong wind (STSW) conditions, long-term moderate wind (LTMW) conditions, and static/calm conditions were investigated. To address this objective, we (1) monitored changes in surface water P composition during field-based sediment resuspension caused by STSW conditions in Lake Taihu, and also conducted (2) a series of laboratory-based sediment resuspension experiments to simulate LTMW and calm conditions. The results showed that under both strong and moderate wind-wave conditions, suspended solids (SS) and total phosphorus (TP) in the water column increased significantly, but total dissolved phosphorus (TDP) and soluble reactive phosphorus (SRP) remained low throughout the experiments, indicating that the P released from sediments mainly existed in particulate forms. In STSW conditions, alkaline phosphatase activity (APA) and enzymatically hydrolysable phosphorus (EHP) increased rapidly, with the peak value occurring following the peak value of wind speed for 1-2 days, and then rapidly decreased after the wind stopped. Under LTMW conditions, APA and EHP increased steadily, and by the end of the laboratory experiments, APA increased by 11 times and EHP increased by 5 times. Chlorophyll a (Chl-a) in LTMW conditions increased significantly, but remained low under STSW conditions, demonstrating that the former type of sediment P release promoted phytoplankton growth more effectively, and the latter type did not. Despite the fact that STSW conditions resulted in the release of more TP, TP settled to the bottom rapidly with SS after the wind stopped, and did not promote algal growth. Under LTMW conditions, suspended particulate P was hydrolyzed to SRP by phosphatase and promoted algae growth. Algal growth in turn secreted more phosphatase and accelerated particulate P regeneration, which may be the main mechanism of sediment bio-available P release that promotes phytoplankton growth in shallow lakes.

What next for environmental health?

PubMed

Dhesi, Surindar; Lynch, Zena

2016-07-01

The aim of the wider research was to explore Health and Wellbeing Boards (HWBs) during their early development stages, with a focus on health inequalities and the role of environmental health (EH). This article presents empirical findings relating to challenges facing the EH profession in the new English public health (PH) system and offers new practical suggestions as to how they might be overcome in relation to educating and training the new generation of EH practitioners (EHPs). Four case study HWBs in the Midlands and North of England were followed for 18 months from early 2012. In addition, EHPs and managers from each English region were interviewed. In total, 50 semi-structured interviews were carried out, around 55 h of HWB meetings were observed, and documents associated with HWBs such as strategies and minutes of meetings were collected. Data were analysed thematically, both inductively and deductively, using Atlas.ti. EH is largely invisible in the new PH system due to a variety of internal and external factors, including existing skill sets and practices. There is a new imperative to move away from reliance on statutory functions for funding and to engage with wider PH issues and colleagues, requiring new skills of evaluation and a change in perception from being 'doers' to include a greater role as 'thinkers'. This is being recognised by EHPs and managers, who are seeking ways to adapt to these new expectations. Recent changes to the English PH system have led to a period of reflection and the beginnings of adaptation in EH to overcome new challenges. Linked to this is a need for graduate training to prepare new practitioners to think critically, to thrive and become high-level managers of the future, while being technically competent. We suggest a new, enhanced role for Chartered Institute of Environmental Health (CIEH)-accredited universities in securing the future of the profession by supporting new graduates. Specifically, a mentoring scheme could be introduced for the practical training element for new practitioners. This would help to embed criticality and evaluation in practice, provide consistency in training, and overcome the disconnect between academia and practice. © Royal Society for Public Health 2015.

Occupational safety and health training in Alaska.

PubMed

Hild, C M

1992-01-01

We have eleven years of experience delivering a wide variety of worker education programs in cross-cultural settings to reduce the levels of occupational fatalities and injuries in Alaska. We published an instructional manual and informational poster for workers, on Alaska's "Right-To-Know" law regarding chemical and physical hazards. The "Job Hazard Recognition Program" curriculum for high school students has received national acclaim for being proactive in dealing with worker safety education before the student becomes a member of the work force. Adult educational programs and materials have been designed to include less lecture and formal presentation, and more practical "hands on" and on-the-job experience for specific trades and hazards. New industry specific manuals deal with hazardous waste reduction as a method to reduce harm to the employee. Difficulty in getting instructors and training equipment to rural locations is dealt with by becoming creative in scheduling classes, using locally available equipment, and finding regional contacts who support the overall program. Alternative approaches to funding sources include building on regional long-term plans and establishing complementary program objectives.

Cross Reference Index for Bioenvironmental Engineer and Military Public Health Offices

DTIC Science & Technology

1992-03-01

Food Recall AFR 161-42 DOD Hazardous Food and Nonprescription Drug Recall System Insects and Mite Pests in Food AGR-HB-655 Insects and Mite Pests in Food...Solution, 11 Hazard Communication, 12 Hazardous Energy Control, 21, 22 Hazardous Food Recall Program, 9 Hazardous Waste, 11, 26 Hazardous Materials...34Institutional Meat Purchase Specification" NAMPS "National Association of Meat Purveyor’s" DPSC Support DOD 4155.6 Subsistence Inspection Manual Hazardous

Hazardous waste management at the local level; The Anchorage, Alaska experience

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wigglesworth, D.

1989-07-01

The need to manage hazardous wastes in the municipality of Anchorage, Alaska, has become increasingly evident in recent years. A task force, representing a broad cross-section of the community, was appointed by the mayor to develop a waste management plan that would address community concerns. Between 1984 and 1986, the Anchorage Hazardous Waste Task Force, supported by municipal staff, local consultants and volunteers from the community developed a plan emphasizing local responsibility and pollution prevention, using management capabilities and technical assistance. This paper describes the development of a non-regulatory hazardous waste management program in Anchorage, Alaska. Plan elements, program fundingmore » and the key role of the local Hazardous Waste Task Force are discussed.« less

Lunar mission safety and rescue: Technical summary

NASA Technical Reports Server (NTRS)

1971-01-01

A technical summary is presented of the escape/rescue and the hazards analyses for manned missions and operations in the 1980 time frame. Hazards are interpreted as hazards to man, not to equipment, program schedule, or program objectives. Hazards in 39 individual areas are analyzed, and corrective measures are recommended. Over 200 safety guidelines are proposed, based on significant hazards. Escape and rescue situtations and requirements are identified and analyzed, and escape/survival/rescue concepts are defined to cope with each escape/rescue situation. Areas in which research or technical development efforts could improve mission safety are identified. It is concluded that the primary emphasis should be on survival and escape provisions, with rescue required only where self-help cannot bring the endangered crewmen to a safe haven.

Staff - Jacquelyn R. Overbeck | Alaska Division of Geological & Geophysical

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in main content Jacquelyn R. Overbeck Jacquelyn R. Overbeck Geomorphology, coastal hazards, remote sensing University, Environmental Science Projects and/or Research Interests As the project manager for the Coastal

76 FR 55908 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-09

... of an exemption to the land disposal restrictions, under the 1984 Hazardous and Solid Waste... Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection; Great Lakes... from the injection zone for as long as the waste remains hazardous. This final decision allows the...

78 FR 23246 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-18

... exemption to the land disposal Restrictions, under the 1984 Hazardous and Solid Waste [[Page 23247... Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection; BASF... from the injection zone for as long as the waste remains hazardous. This final decision allows the...

77 FR 26755 - Underground Injection Control Program; Hazardous Waste Injection Restrictions; Petition for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-07

... reissuance of an exemption to the land disposal Restrictions, under the 1984 Hazardous and Solid Waste... Waste Injection Restrictions; Petition for Exemption--Class I Hazardous Waste Injection; Diamond... from the injection zone for as long as the waste remains hazardous. This final decision allows the...

TECHNICAL GUIDANCE DOCUMENT: INSPECTION TECHNIQUES FOR THE FABRICATION OF GEOMEMBRANE FIELD SEAMS

EPA Science Inventory

Subtitle C of the Resource Conservation and Recovery Act (RCRA) requires the U.S. Environmental Protection Agency (EPA) to establish a Federal hazardous waste management program. This program must ensure that hazardous wastes are handled safely from generation until final dispos...

40 CFR 270.60 - Permits by rule.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) EPA ADMINISTERED PERMIT PROGRAMS: THE HAZARDOUS WASTE PERMIT PROGRAM Special Forms of Permits § 270.60 Permits by... operator of a barge or other vessel which accepts hazardous waste for ocean disposal, if the owner or...

40 CFR 270.60 - Permits by rule.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) EPA ADMINISTERED PERMIT PROGRAMS: THE HAZARDOUS WASTE PERMIT PROGRAM Special Forms of Permits § 270.60 Permits by... operator of a barge or other vessel which accepts hazardous waste for ocean disposal, if the owner or...

78 FR 43263 - Paperless Hazard Communications Pilot Program

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-19

... Research Division (PHH-23), Pipeline and Hazardous Materials Safety Administration, 1200 New Jersey Avenue... materials by air, highway, rail, and water) to test the feasibility and then evaluate both the feasibility... times and locations.'' On September 12, 2001, the Research and Special Programs Administration (the...

NASA's aviation safety - meteorology research programs

NASA Technical Reports Server (NTRS)

Winblade, R. L.

1983-01-01

The areas covering the meteorological hazards program are: severe storms and the hazards to flight generated by severe storms; clear air turbulence; icing; warm fog dissipation; and landing systems. Remote sensing of ozone by satellites, and the use of satellites as data relays is also discussed.

40 CFR 68.87 - Contractors.

Code of Federal Regulations, 2011 CFR

2011-07-01

... ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.87 Contractors. (a) Application. This... known potential fire, explosion, or toxic release hazards related to the contractor's work and the... instructed in the known potential fire, explosion, or toxic release hazards related to his/her job and the...

40 CFR 68.87 - Contractors.

Code of Federal Regulations, 2012 CFR

2012-07-01

... ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.87 Contractors. (a) Application. This... known potential fire, explosion, or toxic release hazards related to the contractor's work and the... instructed in the known potential fire, explosion, or toxic release hazards related to his/her job and the...

40 CFR 68.87 - Contractors.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.87 Contractors. (a) Application. This... known potential fire, explosion, or toxic release hazards related to the contractor's work and the... instructed in the known potential fire, explosion, or toxic release hazards related to his/her job and the...

40 CFR 68.87 - Contractors.

Code of Federal Regulations, 2013 CFR

2013-07-01

... ACCIDENT PREVENTION PROVISIONS Program 3 Prevention Program § 68.87 Contractors. (a) Application. This... known potential fire, explosion, or toxic release hazards related to the contractor's work and the... instructed in the known potential fire, explosion, or toxic release hazards related to his/her job and the...

75 FR 5244 - Pipeline Safety: Integrity Management Program for Gas Distribution Pipelines; Correction

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-02

... Management Program for Gas Distribution Pipelines; Correction AGENCY: Pipeline and Hazardous Materials Safety... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part... Regulations to require operators of gas distribution pipelines to develop and implement integrity management...

Publications - RI 97-14B | Alaska Division of Geological & Geophysical

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in , State of; Alluvial Deposits; Avalanche; Cambrian; Carboniferous; Cenozoic; Coastal and River; Coastal

Publications - RI 2016-2 | Alaska Division of Geological & Geophysical

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in ; Bathymetry; Coastal; Coastal and River; Earthquake Related Slope Failure; Emergency Preparedness; Engineering

49 CFR 109.3 - Inspections and Investigations.

Code of Federal Regulations, 2014 CFR

2014-10-01

....3 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS AND OIL TRANSPORTATION HAZARDOUS MATERIALS PROGRAM PROCEDURES Inspections and Investigations § 109.3 Inspections and Investigations. (a...

A Review of Hazard Anticipation Training Programs for Young Drivers.

PubMed

McDonald, Catherine C; Goodwin, Arthur H; Pradhan, Anuj K; Romoser, Matthew R E; Williams, Allan F

2015-07-01

Poor hazard anticipation skills are a risk factor associated with high motor vehicle crash rates of young drivers. A number of programs have been developed to improve these skills. The purpose of this review was to assess the empirical literature on hazard anticipation training for young drivers. Studies were included if they (1) included an assessment of hazard anticipation training outcomes; (2) were published between January 1, 1980 and December 31, 2013 in an English language peer-reviewed journal or conference proceeding; and (3) included at least one group that uniquely comprised a cohort of participants aged <21 years. Nineteen studies met inclusion criteria. Studies used a variety of training methods including interactive computer programs, videos, simulation, commentary driving, or a combination of approaches. Training effects were predominantly measured through computer-based testing and driving simulation with eye tracking. Four studies included an on-road evaluation. Most studies evaluated short-term outcomes (immediate or few days). In all studies, young drivers showed improvement in selected hazard anticipation outcomes but none investigated crash effects. Although there is promise in existing programs, future research should include long-term follow-up, evaluate crash outcomes, and assess the optimal timing of hazard anticipation training taking into account the age and experience level of young drivers. Copyright © 2015 Society for Adolescent Health and Medicine. All rights reserved.

Evaluation of a Home-Based Environmental and Educational Intervention to Improve Health in Vulnerable Households: Southeastern Pennsylvania Lead and Healthy Homes Program.

PubMed

Mankikar, Deepa; Campbell, Carla; Greenberg, Rachael

2016-09-09

This evaluation examined whether participation in a home-based environmental educational intervention would reduce exposure to health and safety hazards and asthma-related medical visits. The home intervention program focused on vulnerable, low-income households, where children had asthma, were at risk for lead poisoning, or faced multiple unsafe housing conditions. Home visitors conducted two home visits, two months apart, consisting of an environmental home assessment, Healthy Homes education, and distribution of Healthy Homes supplies. Measured outcomes included changes in participant knowledge and awareness of environmental home-based hazards, rate of children's asthma-related medical use, and the presence of asthma triggers and safety hazards. Analysis of 2013-2014 baseline and post-intervention program data for a cohort of 150 families revealed a significantly lower three-month rate (p < 0.05) of children's asthma-related doctor visits and hospital admissions at program completion. In addition, there were significantly reduced reports of the presence of home-based hazards, including basement or roof leaks (p = 0.011), plumbing leaks (p = 0.019), and use of an oven to heat the home (p < 0.001). Participants' pre- and post- test scores showed significant improvement (p < 0.05) in knowledge and awareness of home hazards. Comprehensive home interventions may effectively reduce environmental home hazards and improve the health of asthmatic children in the short term.

Publications of the Volcano Hazards Program 2010

USGS Publications Warehouse

Nathenson, Manuel

2012-01-01

The Volcano Hazards Program of the U.S. Geological Survey (USGS) is part of the Geologic Hazards Assessments subactivity as funded by Congressional appropriation. Investigations are carried out in the USGS and with cooperators at the Alaska Division of Geological and Geophysical Surveys, University of Alaska Fairbanks Geophysical Institute, University of Hawaii Manoa and Hilo, University of Utah, and University of Washington Geophysics Program. This report lists publications from all these institutions. Only published papers and maps are included here; numerous abstracts presented at scientific meetings are omitted. Publication dates are based on year of issue, with no attempt to assign them to fiscal year.

Publications of the Volcano Hazards Program 2012

USGS Publications Warehouse

Nathenson, Manuel

2014-01-01

The Volcano Hazards Program of the U.S. Geological Survey (USGS) is part of the Geologic Hazards Assessments subactivity, as funded by Congressional appropriation. Investigations are carried out by the USGS and with cooperators at the Alaska Division of Geological and Geophysical Surveys, University of Alaska Fairbanks Geophysical Institute, University of Hawaii Manoa and Hilo, University of Utah, and University of Washington Geophysics Program. This report lists publications from all of these institutions. Only published papers and maps are included here; abstracts presented at scientific meetings are omitted. Publication dates are based on year of issue, with no attempt to assign them to a fiscal year.

Publications of the Volcano Hazards Program 2009

USGS Publications Warehouse

Nathenson, Manuel

2011-01-01

The Volcano Hazards Program of the U.S. Geological Survey (USGS) is part of the Geologic Hazards Assessments subactivity as funded by congressional appropriation. Investigations are carried out in the USGS and with cooperators at the Alaska Division of Geological and Geophysical Surveys, University of Alaska Fairbanks Geophysical Institute, University of Hawaii Manoa and Hilo, University of Utah, and University of Washington Geophysics Program. This report lists publications from all these institutions. Only published papers and maps are included here; numerous abstracts presented at scientific meetings are omitted. Publications dates are based on year of issue, with no attempt to assign them to fiscal year.

Publications of Volcano Hazards Program 2000

USGS Publications Warehouse

Nathenson, Manuel

2001-01-01

The Volcano Hazards Program of the U.S. Geological Survey (USGS) is part of the Geologic Hazards Assessments subactivity as funded by Congressional appropriation. Investigations are carried out in the Geology and Hydrology Disciplines of the USGS and with cooperators at the Alaska Division of Geological and Geophysical Surveys, University of Alaska Fairbanks Geophysical Institute, University of Utah, and University of Washington Geophysics Program. This report lists publications from all these institutions. This report contains only published papers and maps; numerous abstracts produced for presentations at scientific meetings have not been included. Publications are included based on date of publication with no attempt to assign them to Fiscal Year.

Publications of the Volcano Hazards Program 1997

USGS Publications Warehouse

Nathenson, Manuel

1998-01-01

The Volcano Hazards Program of the U.S. Geological Survey (USGS) is part of the Geologic Hazards Assessments subactivity as funded by Congressional appropriation. Investigations are carried out in the Geologic and Water Resources Divisions of the USGS and with cooperators at the Alaska Division of Geological and Geophysical Surveys, University of Alaska Fairbanks Geophysical Institute, University of Utah, and University of Washington Geophysics Program. This report lists publications from all these institutions. This report contains only published papers and maps; numerous abstracts produced for presentations at scientific meetings have not been included. Publications are included based on date of publication with no attempt to assign them to Fiscal Year.

NASA's Space Environments and Effects (SEE) Program

NASA Technical Reports Server (NTRS)

Kauffman, Billy; Hardage, Donna; Minor, Jody; Barth, Janet; LaBel, Ken

2003-01-01

This viewgraph presentation gives a broad overview of NASA's Space Enivronments and Effects (SEE) Program. The purpose of the program is to protect spacecraft and their systems from damage by radiation, spacecraft charging, micrometeoroids, contamination, and other hazards posed by aerospace environments. The presentation profiles SEE activities to address each of these hazards. SEE is responsible for overseeing research and product development with a variety of partners.

29 CFR 1926.503 - Training requirements.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Fall Protection § 1926.503 Training requirements... training program for each employee who might be exposed to fall hazards. The program shall enable each employee to recognize the hazards of falling and shall train each employee in the procedures to be followed...

29 CFR 1926.503 - Training requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Fall Protection § 1926.503 Training requirements... training program for each employee who might be exposed to fall hazards. The program shall enable each employee to recognize the hazards of falling and shall train each employee in the procedures to be followed...

29 CFR 1926.503 - Training requirements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Fall Protection § 1926.503 Training requirements... training program for each employee who might be exposed to fall hazards. The program shall enable each employee to recognize the hazards of falling and shall train each employee in the procedures to be followed...

29 CFR 1926.503 - Training requirements.

Code of Federal Regulations, 2011 CFR

2011-07-01

... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Fall Protection § 1926.503 Training requirements... training program for each employee who might be exposed to fall hazards. The program shall enable each employee to recognize the hazards of falling and shall train each employee in the procedures to be followed...

29 CFR 1926.503 - Training requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Fall Protection § 1926.503 Training requirements... training program for each employee who might be exposed to fall hazards. The program shall enable each employee to recognize the hazards of falling and shall train each employee in the procedures to be followed...

Publications - RDF 2015-2 | Alaska Division of Geological & Geophysical

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in -bay Shapefile 24.5 M Metadata - Read me Keywords Bathymetry; Bering Sea; Chukchi Sea; Coastal; Gambell

There's Life in Hazard Trees

Treesearch

Mary Torsello; Toni McLellan

The goals of hazard tree management programs are to maximize public safety and maintain a healthy sustainable tree resource. Although hazard tree management frequently targets removal of trees or parts of trees that attract wildlife, it can take into account a diversity of tree values. With just a little extra planning, hazard tree management can be highly beneficial...

Waste certification program plan for Oak Ridge National Laboratory. Revision 2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1997-09-01

This document defines the waste certification program (WCP) developed for implementation at Oak Ridge National Laboratory (ORNL). The document describes the program structure, logic, and methodology for certification of ORNL wastes. The purpose of the WCP is to provide assurance that wastes are properly characterized and that the Waste Acceptance Criteria (WAC) for receiving facilities are met. The program meets the waste certification requirements for mixed (both radioactive and hazardous) and hazardous [including polychlorinated biphenyls (PCB)] waste. Program activities will be conducted according to ORNL Level 1 document requirements.

Hazard calculations of diffuse reflected laser radiation for the SELENE program

NASA Technical Reports Server (NTRS)

Miner, Gilda A.; Babb, Phillip D.

1993-01-01

The hazards from diffuse laser light reflections off water clouds, ice clouds, and fog and from possible specular reflections off ice clouds were assessed with the American National Standards (ANSI Z136.1-1986) for the free-electron-laser parameters under consideration for the Segmented Efficient Laser Emission for Non-Nuclear Electricity (SELENE) Program. Diffuse laser reflection hazards exist for water cloud surfaces less than 722 m in altitude and ice cloud surfaces less than 850 m in altitude. Specular reflections from ice crystals in cirrus clouds are not probable; however, any specular reflection is a hazard to ground observers. The hazard to the laser operators and any ground observers during heavy fog conditions is of such significant magnitude that the laser should not be operated in fog.

DOE Office of Scientific and Technical Information (OSTI.GOV)

R. Camp

Over the past four years, the Electrical Safety Program at PPPL has evolved in addressing changing regulatory requirements and lessons learned from accident events, particularly in regards to arc flash hazards and implementing NFPA 70E requirements. This presentation will discuss PPPL's approaches to the areas of electrical hazards evaluation, both shock and arc flash; engineered solutions for hazards mitigation such as remote racking of medium voltage breakers, operational changes for hazards avoidance, targeted personnel training and hazard appropriate personal protective equipment. Practical solutions for nominal voltage identification and zero voltage checks for lockout/tagout will also be covered. Finally, we willmore » review the value of a comprehensive electrical drawing program, employee attitudes expressed as a personal safety work ethic, integrated safety management, and sustained management support for continuous safety improvement.« less

PRELIMINARY ANALYSIS OF HAZARDOUS AIR POLLUTANT EMISSION INVENTORIES FROM THREE MAJOR URBAN AREAS

EPA Science Inventory

The paper reports EPA/AEERL's progress on emissions inventory evaluation and improvement under a hazardous air pollutant (HAP) emissions research program in support of the Urban Area Source Program required under Title III of the Clean Air Act Amendments of 1990 (CAAA). he paper ...

Risk Management in Adventure Programs with Special Populations: Two Hidden Dangers.

ERIC Educational Resources Information Center

Stich, Thomas; Gaylor, Michael S.

The paper addresses two significant risk management considerations in conducting an adventure program in a therapeutic setting: the potential hazards of psychiatric medications and psychological emergencies. Focusing on the potential hazards of psychiatric medications, the first section discusses climatic conditions (heat, cold, and sun) and the…

Employee health surveillance in the health care industry.

PubMed

Hood, Joyce; Larrañaga, Michael

2007-10-01

This article provides an overview of the fundamental and inherent challenges in developing a health surveillance program for a health care facility. These challenges are similar to those facing individuals responsible for developing health surveillance programs for multiple industries because several "mini-industries" exist within hospitals. Hazards can range from those that are regulated by the Occupational Safety and Health Administration to those that are unregulated but pose a threat to health care workers. Occupational hazards that are unique to the health care industry also exist. A health surveillance program can be developed with focused assessment and a strong occupational safety and health program. Implementation can occur within a health care setting with the buy-in of the many stakeholders involved, especially supervisors managing departments where chemical and other hazards are present.

Guidance Manual for Integrating Hazardous Material Control and Management into System Acquisition Programs

DTIC Science & Technology

1993-04-01

34 in the remainder of this "• IPS. Ensure that system safety, Section refer to the DoD format paragraph health hazards, and environmental for the...hazardous materials is controlled in the manner which protects human health and the environment at the least cost. Hazardous Material Control and Management...of hazardous materials is controlled in a manner which protects human health and the environment at the least cost. Hazardous Material Control and

PRESENTED AT COPENHAGEN WORKSHOP ON ENVIRONMENTAL, REPRODUCTIVE HEALTH AND FERTILITY, COPENHAGEN, DENMARK, 1/15-18/2005: GST M1 GENOTYPE INFLUENCES SPERM DNA DAMAGE ASSOCIATED WITH EXPOSURE TO AIR POLLUTION

EPA Science Inventory

Exposure to episodic air pollution in the Czech Republic has been associated with abnormal semen quality and sperm DNA damage (EHP 108:887;2000). A subsequent longitudinal study evaluated semen from 36 men sampled up to 7 times over a period of two years to capture exposures dur...

Publications - RDF 2014-20 | Alaska Division of Geological & Geophysical

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in Download golovin-lidar-las-index Shapefile 71.0 K Metadata - Read me Keywords Coastal; Coastal and River

Publications - RI 2000-1D | Alaska Division of Geological & Geophysical

Science.gov Websites

Tidal Datum Portal Climate and Cryosphere Hazards Coastal Hazards Program Guide to Geologic Hazards in - Read me Keywords Arctic National Wildlife Refuge; Aufeis; Brooks Range; Coastal and River; Coastal and

40 CFR 63.1210 - What are the notification requirements?

Code of Federal Regulations, 2011 CFR

2011-07-01

...? 63.1210 Section 63.1210 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES National Emission Standards for Hazardous Air Pollutants from Hazardous Waste Combustors Notification...

40 CFR 63.1210 - What are the notification requirements?

Code of Federal Regulations, 2010 CFR

2010-07-01

...? 63.1210 Section 63.1210 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS FOR SOURCE CATEGORIES National Emission Standards for Hazardous Air Pollutants from Hazardous Waste Combustors Notification...

44 CFR 361.7 - General eligible expenditures.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.7 General eligible expenditures... specifically for carrying out earthquake hazards reduction activities are eligible when engaged in the...

44 CFR 361.7 - General eligible expenditures.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.7 General eligible expenditures... specifically for carrying out earthquake hazards reduction activities are eligible when engaged in the...

44 CFR 361.7 - General eligible expenditures.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.7 General eligible expenditures... specifically for carrying out earthquake hazards reduction activities are eligible when engaged in the...

44 CFR 361.7 - General eligible expenditures.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.7 General eligible expenditures... specifically for carrying out earthquake hazards reduction activities are eligible when engaged in the...

44 CFR 361.7 - General eligible expenditures.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.7 General eligible expenditures... specifically for carrying out earthquake hazards reduction activities are eligible when engaged in the...

An integrated environmental and health performance quantification model for pre-occupancy phase of buildings in China

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Xiaodong, E-mail: eastdawn@tsinghua.edu.cn; Su, Shu, E-mail: sushuqh@163.com; Zhang, Zhihui, E-mail: zhzhg@tsinghua.edu.cn

To comprehensively pre-evaluate the damages to both the environment and human health due to construction activities in China, this paper presents an integrated building environmental and health performance (EHP) assessment model based on the Building Environmental Performance Analysis System (BEPAS) and the Building Health Impact Analysis System (BHIAS) models and offers a new inventory data estimation method. The new model follows the life cycle assessment (LCA) framework and the inventory analysis step involves bill of quantity (BOQ) data collection, consumption data formation, and environmental profile transformation. The consumption data are derived from engineering drawings and quotas to conduct the assessmentmore » before construction for pre-evaluation. The new model classifies building impacts into three safeguard areas: ecosystems, natural resources and human health. Thus, this model considers environmental impacts as well as damage to human wellbeing. The monetization approach, distance-to-target method and panel method are considered as optional weighting approaches. Finally, nine residential buildings of different structural types are taken as case studies to test the operability of the integrated model through application. The results indicate that the new model can effectively pre-evaluate building EHP and the structure type significantly affects the performance of residential buildings.« less

Hypoplasia-associated Severe Early Childhood Caries – A Proposed Definition

PubMed Central

Caufield, P.W.; Li, Y.; Bromage, T.G.

2012-01-01

We propose a new classification of severe early childhood caries (S-ECC): hypoplasia-associated severe early childhood caries (HAS-ECC). This form of caries affects mostly young children living at or below poverty, characterized by structurally damaged primary teeth that are particularly vulnerable to dental caries. These predisposing developmental dental defects are mainly permutations of enamel hypoplasia (EHP). Anthropologists and dental researchers consider EHP an indicator for infant and maternal stresses including malnutrition, a variety of illnesses, and adverse birthing conditions. Differentiation of HAS-ECC from other forms of early childhood caries is warranted because of its distinct etiology, clinical presentation, and eventual management. Defining HAS-ECC has important clinical implications: Therapies that control or prevent other types of caries are likely to be less effective with HAS-ECC because the structural integrity of the teeth is compromised prior to their emergence into the oral cavity. By the time these children present to the dentist, the treatment options often become limited to surgical management under general anesthesia. To prevent HAS-ECC, dentists must partner with other health providers to develop interventions that begin with pregnant mothers, with the aim of eliminating or ameliorating the covariates accompanying poverty, including better pre- and post-natal care and nutrition. PMID:22529242

The health hazard assessment process in support of joint weapon system acquisitions.

PubMed

Kluchinsky, Timothy A; Jokel, Charles R; Cambre, John V; Goddard, Donald E; Batts, Robert W

2013-01-01

Since 1981, the Army's HHA Program has provided an invaluable service to combat developers and materiel program managers by providing recommendations designed to eliminate or control health hazards associated with materiel and weapon systems. The program has consistently strived to improve its services by providing more meaningful and efficient assistance to the acquisition community. In the uncertain fiscal times ahead, the Army's HHA Program will continue to provide valuable and cost-effective solutions to mitigate the health risks of weapons systems.

Examining Lead Exposures in California through State-Issued Health Alerts for Food Contamination and an Exposure-Based Candy Testing Program.

PubMed

Handley, Margaret A; Nelson, Kali; Sanford, Eric; Clarity, Cassidy; Emmons-Bell, Sophia; Gorukanti, Anuhandra; Kennelly, Patrick

2017-10-26

In California, the annual number of children under age 6 y of age with blood lead levels (BLL) ≥10μg/dL is estimated at over 1,000 cases, and up to 10,000 cases when BLL between 4.5 and 9.5 μg/dL are included. State-issued health alerts for food contamination provide one strategy for tracking sources of food-related lead exposures. As well, California passed legislation in 2006 for the Food and Drug Branch (FDB) of the state health department to test and identify lead in candy. This report presents health alert data from California over a 14-y period, compares data before and after the candy testing program began, and examines country of origin, ZIP code data, and time from candy testing to release of health alerts for lead-contaminated candies for 2011-2012. After 2007, health alerts issued for lead in candy and food increased significantly. Analysis of candy-testing data indicated that multiple counties and ZIP codes were affected. Seventeen candies with high lead concentrations were identified, resulting in rapid dissemination (<2wk) of health alerts to local health departments and community clinicians and to the public. Surveillance of lead exposures from state-based food and candy testing programs provides an opportunity to identify and immediately act to remove nonpaint sources of lead affecting children. https://doi.org/10.1289/EHP2582.

The Effects of Embedded Generative Learning Strategies and Collaboration on Knowledge Acquisition in a Cognitive Flexibility-Based Computer Learning Environment

DTIC Science & Technology

1998-08-07

cognitive flexibility theory and generative learning theory which focus primarily on the individual student’s cognitive development , collaborative... develop "Handling Transfusion Hazards," a computer program based upon cognitive flexibility theory principles. The Program: Handling Transfusion Hazards...computer program was developed according to cognitive flexibility theory principles. A generative version was then developed by embedding

33 CFR 150.628 - How must the operator label, tag, and mark a container of hazardous material?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Workplace Safety and Health Hazard Communication Program § 150.628 How must the operator label, tag, and..., reactive and other special condition hazard warnings. The only exception is for portable containers that...

14 CFR 121.1003 - Hazardous materials training: General.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Hazardous materials training: General. 121.1003 Section 121.1003 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1003 - Hazardous materials training: General.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Hazardous materials training: General. 121.1003 Section 121.1003 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1007 - Hazardous materials training records.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Hazardous materials training records. 121.1007 Section 121.1007 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1005 - Hazardous materials training required.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Hazardous materials training required. 121.1005 Section 121.1005 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1005 - Hazardous materials training required.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Hazardous materials training required. 121.1005 Section 121.1005 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1003 - Hazardous materials training: General.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Hazardous materials training: General. 121.1003 Section 121.1003 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1005 - Hazardous materials training required.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 14 Aeronautics and Space 3 2014-01-01 2014-01-01 false Hazardous materials training required. 121.1005 Section 121.1005 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1007 - Hazardous materials training records.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Hazardous materials training records. 121.1007 Section 121.1007 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1005 - Hazardous materials training required.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Hazardous materials training required. 121.1005 Section 121.1005 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1007 - Hazardous materials training records.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Hazardous materials training records. 121.1007 Section 121.1007 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1007 - Hazardous materials training records.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Hazardous materials training records. 121.1007 Section 121.1007 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1005 - Hazardous materials training required.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 3 2011-01-01 2011-01-01 false Hazardous materials training required. 121.1005 Section 121.1005 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1003 - Hazardous materials training: General.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 3 2013-01-01 2013-01-01 false Hazardous materials training: General. 121.1003 Section 121.1003 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1007 - Hazardous materials training records.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Hazardous materials training records. 121.1007 Section 121.1007 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

14 CFR 121.1003 - Hazardous materials training: General.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 3 2012-01-01 2012-01-01 false Hazardous materials training: General. 121.1003 Section 121.1003 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Hazardous Materials Training Program...

44 CFR 361.6 - Documentation of matching contributions.

Code of Federal Regulations, 2012 CFR

2012-10-01

..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.6 Documentation of matching... comprising its earthquake hazards reduction project, including the project budget, shall reflect a level of...

44 CFR 361.6 - Documentation of matching contributions.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.6 Documentation of matching... comprising its earthquake hazards reduction project, including the project budget, shall reflect a level of...

44 CFR 361.6 - Documentation of matching contributions.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.6 Documentation of matching... comprising its earthquake hazards reduction project, including the project budget, shall reflect a level of...

78 FR 12780 - Agency Information Collection Activities: Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-25

... INFORMATION CONTACT: To request additional information about this ICR, Elizabeth Lemersal, Earthquake Hazards... . SUPPLEMENTARY INFORMATION: Title: Earthquake Hazards Program Research and Monitoring. OMB Control Number: 1028... findings are essential to fulfilling USGS's responsibility under the Earthquake Hazards Reduction Act to...

44 CFR 361.6 - Documentation of matching contributions.

Code of Federal Regulations, 2011 CFR

2011-10-01

..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.6 Documentation of matching... comprising its earthquake hazards reduction project, including the project budget, shall reflect a level of...

44 CFR 361.6 - Documentation of matching contributions.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS NATIONAL EARTHQUAKE HAZARDS REDUCTION ASSISTANCE TO STATE AND LOCAL GOVERNMENTS Earthquake Hazards Reduction Assistance Program § 361.6 Documentation of matching... comprising its earthquake hazards reduction project, including the project budget, shall reflect a level of...

Evaluation of a Home-Based Environmental and Educational Intervention to Improve Health in Vulnerable Households: Southeastern Pennsylvania Lead and Healthy Homes Program

PubMed Central

Mankikar, Deepa; Campbell, Carla; Greenberg, Rachael

2016-01-01

This evaluation examined whether participation in a home-based environmental educational intervention would reduce exposure to health and safety hazards and asthma-related medical visits. The home intervention program focused on vulnerable, low-income households, where children had asthma, were at risk for lead poisoning, or faced multiple unsafe housing conditions. Home visitors conducted two home visits, two months apart, consisting of an environmental home assessment, Healthy Homes education, and distribution of Healthy Homes supplies. Measured outcomes included changes in participant knowledge and awareness of environmental home-based hazards, rate of children’s asthma-related medical use, and the presence of asthma triggers and safety hazards. Analysis of 2013–2014 baseline and post-intervention program data for a cohort of 150 families revealed a significantly lower three-month rate (p < 0.05) of children’s asthma-related doctor visits and hospital admissions at program completion. In addition, there were significantly reduced reports of the presence of home-based hazards, including basement or roof leaks (p = 0.011), plumbing leaks (p = 0.019), and use of an oven to heat the home (p < 0.001). Participants’ pre- and post- test scores showed significant improvement (p < 0.05) in knowledge and awareness of home hazards. Comprehensive home interventions may effectively reduce environmental home hazards and improve the health of asthmatic children in the short term. PMID:27618087

25 CFR 170.905 - How can tribes obtain training in handling hazardous material?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 1 2011-04-01 2011-04-01 false How can tribes obtain training in handling hazardous... Transportation § 170.905 How can tribes obtain training in handling hazardous material? (a) Tribes cannot use IRR Program funds to train personnel to handle radioactive and hazardous material. (b) Tribes can seek...

Publications of the Volcano Hazards Program 2005

USGS Publications Warehouse

Nathenson, Manuel

2007-01-01

The Volcano Hazards Program of the U.S. Geological Survey (USGS) is part of the Geologic Hazards Assessments subactivity as funded by Congressional appropriation. Investigations are carried out in the Geology and Hydrology Disciplines of the USGS and with cooperators at the Alaska Division of Geological and Geophysical Surveys, University of Alaska Fairbanks Geophysical Institute, University of Hawaii Hilo, University of Utah, and University of Washington Geophysics Program. This report lists publications from all these institutions. This report contains only published papers and maps; numerous abstracts produced for presentations at scientific meetings have not been included. Publications are included based on date of publication with no attempt to assign them to Fiscal Year.

Publications of the Volcano Hazards Program 2002

USGS Publications Warehouse

Nathenson, Manuel

2004-01-01

The Volcano Hazards Program of the U.S. Geological Survey (USGS) is part of the Geologic Hazards Assessments subactivity as funded by Congressional appropriation. Investigations are carried out in the Geology and Hydrology Disciplines of the USGS and with cooperators at the Alaska Division of Geological and Geophysical Surveys, University of Alaska Fairbanks Geophysical Institute, University of Hawaii Hilo, University of Utah, and University of Washington Geophysics Program. This report lists publications from all these institutions. This report contains only published papers and maps; numerous abstracts produced for presentations at scientific meetings have not been included. Publications are included based on date of publication with no attempt to assign them to Fiscal Year.

Publications of the Volcano Hazards Program 2006

USGS Publications Warehouse

Nathenson, Manuel

2008-01-01

The Volcano Hazards Program of the U.S. Geological Survey (USGS) is part of the Geologic Hazards Assessments subactivity as funded by Congressional appropriation. Investigations are carried out in the Geology and Hydrology Disciplines of the USGS and with cooperators at the Alaska Division of Geological and Geophysical Surveys, University of Alaska Fairbanks Geophysical Institute, University of Hawaii Hilo, University of Utah, and University of Washington Geophysics Program. This report lists publications from all these institutions. This report contains only published papers and maps; numerous abstracts produced for presentations at scientific meetings have not been included. Publications are included based on date of publication with no attempt to assign them to Fiscal Year.

Publications of the Volcano Hazards Program 2007

USGS Publications Warehouse

Nathenson, Manuel

2009-01-01

The Volcano Hazards Program of the U.S. Geological Survey (USGS) is part of the Geologic Hazards Assessments subactivity as funded by Congressional appropriation. Investigations are carried out in the Geology and Hydrology Disciplines of the USGS and with cooperators at the Alaska Division of Geological and Geophysical Surveys, University of Alaska Fairbanks Geophysical Institute, University of Hawaii Hilo, University of Utah, and University of Washington Geophysics Program. This report lists publications from all these institutions. This report contains only published papers and maps; numerous abstracts produced for presentations at scientific meetings have not been included. Publications are included based on date of publication with no attempt to assign them to Fiscal Year.

Publications of the Volcano Hazards Program 2004

USGS Publications Warehouse

Nathenson, Manuel

2006-01-01

The Volcano Hazards Program of the U.S. Geological Survey (USGS) is part of the Geologic Hazards Assessments subactivity as funded by Congressional appropriation. Investigations are carried out in the Geology and Hydrology Disciplines of the USGS and with cooperators at the Alaska Division of Geological and Geophysical Surveys, University of Alaska Fairbanks Geophysical Institute, University of Hawaii Hilo, University of Utah, and University of Washington Geophysics Program. This report lists publications from all these institutions. This bibliographic report contains only published papers and maps; numerous abstracts produced for presentations at scientific meetings have not been included. Publications are included based on date of publication with no attempt to assign them to Fiscal Year.

Publications of the Volcano Hazards Program 2001

USGS Publications Warehouse

Nathenson, Manuel

2002-01-01

The Volcano Hazards Program of the U.S. Geological Survey (USGS) is part of the Geologic Hazards Assessments subactivity as funded by Congressional appropriation. Investigations are carried out in the Geology and Hydrology Disciplines of the USGS and with cooperators at the Alaska Division of Geological and Geophysical Surveys, University of Alaska Fairbanks Geophysical Institute, University of Hawaii Hilo, University of Utah, and University of Washington Geophysics Program. This report lists publications from all these institutions. This report contains only published papers and maps; numerous abstracts produced for presentations at scientific meetings have not been included. Publications are included based on date of publication with no attempt to assign them to Fiscal Year.

Publications of the Volcano Hazards Program 2008

USGS Publications Warehouse

Nathenson, Manuel

2010-01-01

The Volcano Hazards Program of the U.S. Geological Survey (USGS) is part of the Geologic Hazards Assessments subactivity as funded by Congressional appropriation. Investigations are carried out in the Geology and Hydrology Disciplines of the USGS and with cooperators at the Alaska Division of Geological and Geophysical Surveys, University of Alaska Fairbanks Geophysical Institute, University of Hawaii Manoa and Hilo, University of Utah, and University of Washington Geophysics Program. This report lists publications from all these institutions. This report contains only published papers and maps; numerous abstracts produced for presentations at scientific meetings have not been included. Publications are included based on date of publication with no attempt to assign them to Fiscal Year.

Program and plans of the U.S. Geological Survey for producing information needed in National Seismic hazards and risk assessment, fiscal years 1980-84

USGS Publications Warehouse

Hays, Walter W.

1979-01-01

In accordance with the provisions of the Earthquake Hazards Reduction Act of 1977 (Public Law 95-124), the U.S. Geological Survey has developed comprehensive plans for producing information needed to assess seismic hazards and risk on a national scale in fiscal years 1980-84. These plans are based on a review of the needs of Federal Government agencies, State and local government agencies, engineers and scientists engaged in consulting and research, professional organizations and societies, model code groups, and others. The Earthquake Hazards Reduction Act provided an unprecedented opportunity for participation in a national program by representatives of State and local governments, business and industry, the design professions, and the research community. The USGS and the NSF (National Science Foundation) have major roles in the national program. The ultimate goal of the program is to reduce losses from earthquakes. Implementation of USGS research in the Earthquake Hazards Reduction Program requires the close coordination of responsibility between Federal, State and local governments. The projected research plan in national seismic hazards and risk for fiscal years 1980-84 will be accomplished by USGS and non-USGS scientists and engineers. The latter group will participate through grants and contracts. The research plan calls for (1) national maps based on existing methods, (2) improved definition of earthquake source zones nationwide, (3) development of improved methodology, (4) regional maps based on the improved methodology, and (5) post-earthquake investigations. Maps and reports designed to meet the needs, priorities, concerns, and recommendations of various user groups will be the products of this research and provide the technical basis for improved implementation.

Safer Schools: Achieving a Healthy Learning Environment through Integrated Pest Management.

ERIC Educational Resources Information Center

2003

Integrated pest management (IPM) is a program of prevention, monitoring, and control that offers the opportunity to eliminate or drastically reduce hazardous pesticide use. IPM is intended to establish a program that uses cultural, mechanical, biological, and other non-toxic practices, and only introduces least-hazardous chemicals as a last…

The Psychometric Properties of the Agricultural Hazardous Occupations Order Certification Training Program Written Examinations

ERIC Educational Resources Information Center

French, Brian F.; Breidenbach, Daniel H.; Field, William E.; Tormoehlen, Roger

2007-01-01

The written certification exam that accompanies the Gearing Up for Safety-Agricultural Production Safety Training for Youth curriculum was designed to partially meet the testing requirements of the Agricultural Hazardous Occupations Order (AgHOs) Certification Training Program. This curriculum and accompanying assessment tools are available for…

33 CFR 150.623 - What are the requirements for protecting personnel from hazards associated with confined spaces?

Code of Federal Regulations, 2011 CFR

2011-07-01

... associated with entering the port's confined spaces, and develop a confined space safe entry program that... implement the confined space safe entry program, the deepwater port operator must determine the education... protecting personnel from hazards associated with confined spaces? 150.623 Section 150.623 Navigation and...

77 FR 69765 - Colorado: Final Authorization of State Hazardous Waste Management Program Revisions

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-21

... Protection Agency (EPA). ACTION: Final rule. SUMMARY: The Solid Waste Disposal Act, as amended, commonly... revised program application, subject to the limitations of the Hazardous and Solid Waste Amendments of... under the authority of sections 2002(a), 3006, and 7004(b) of the Solid Waste Disposal Act as amended 42...

76 FR 26681 - Wisconsin: Incorporation by Reference of Approved State Hazardous Waste Management Program

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-09

... that are authorized and that the EPA will enforce under the Solid Waste Disposal Act, commonly referred...: This action is issued under the authority of sections 2002(a), 3006 and 7004(b) of the Solid Waste and... of Approved State Hazardous Waste Management Program AGENCY: Environmental Protection Agency (EPA...

77 FR 13200 - Texas: Final Authorization of State Hazardous Waste Management Program Revision

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-06

....1. Such wastes are termed ``oil and gas wastes.'' The TCEQ has responsibility to administer the RCRA program, however, hazardous waste generated at natural gas or natural gas liquids processing plants or... with the exploration, development, or production of oil or gas or geothermal resources and other...

77 FR 70724 - Eligibility of the Republic of Korea To Export Poultry Products to the United States

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-27

...) official controls over condemned product; (8) a Hazard Analysis and Critical Control Point (HACCP) system...) Hazard Analysis and Critical Control Point (HACCP) Systems, (5) Chemical Residue Testing Programs, and (6) Microbiological Testing Programs. FSIS evaluates the information submitted to verify that the critical points in...

Environmental health literacy in support of social action: an environmental justice perspective.

PubMed

White, Brandi M; Hall, Eric S; Johnson, Cheryl

2014-01-01

Different demographic groups in the U.S. experience unequal exposures to environmental hazards, i.e., 56% of the population in neighborhoods containing commercial waste facilities are people of color, with the associated poverty rates in those communities being 50% higher than in neighborhoods without commercial waste facilities. Developing programs to educate communities about environmental hazards affecting their health and quality of life is an essential component for a community to understand their true risk. The study described in this article examined the risk of environmental hazards as perceived by public housing residents and assessed the residents' preference for educational programs on environmental hazards. Residents perceived their risk factors in a broad context and they included environmental health risks caused by pollutants along with physical safety concerns from crime and law enforcement interactions. The most trusted sources of information on environmental health include community organizations, trusted individuals in the community, and television programs. Recommendations for developing community-specific environmental health education programs include using sources of environmental health information that community members trust.

Risk Management for Wilderness Programs.

ERIC Educational Resources Information Center

Schimelpfenig, Tod

This paper discusses subjective hazards in wilderness activities and suggests means of assessing and managing related risks. Wilderness educators conveniently group hazards into objective and subjective ones. Objective hazards such as rockfall, moving water, and weather, while not necessarily predictable, are visible and understandable. Subjective…

A comparison of the Landsat image and LAHARZ-simulated lahar inundation hazard zone by the 2010 Merapi eruption

NASA Astrophysics Data System (ADS)

Lee, Seul-Ki; Lee, Chang-Wook; Lee, Saro

2015-06-01

Located above the Java subduction zone, Merapi Volcano is an active stratovolcano with a volcanic activity cycle of 1-5 years. Most Merapi eruptions are relatively small with volcanic explosivity index (VEI) of 1-3. However, the most recent eruption, which occurred in 2010, was quite violent with a VEI of 4 and 386 people were killed. In this study, lahars and pyroclastic flow zones were detected using optical Landsat images and the lahar and pyroclastic flow zone simulated using the LAHARZ program. To detect areal extents of lahar and pyroclastic flows using Landsat images, supervised classification was performed after atmospheric correction by using a cosine of the solar zenith correction (COST) model. As a result, the extracted dimensions of pyroclastic flows are nearly identical to the Calatrava Volcanic Province (CVP) monthly reports. Then, areas of potential lahar and pyroclastic flow inundation based on flow volume using the LAHARZ program were simulated and mapped. Finally, the detected lahars and pyroclastic flow zones were compared with the simulated potential zones using LAHARZ program and verified. Results showed satisfactory similarity (55.63 %) between the detected and simulated zone. The simulated zones using the LAHARZ program can be used as an essential volcanic hazard map for preventing life and property damages for Merapi Volcano and other hazardous volcanic areas. Also, the LAHARZ program can be used to map volcano hazards in other hazardous volcanic areas.

Radon Risk Communication Strategies: A Regional Story.

PubMed

Cheng, Winnie

2016-01-01

Risk communication on the health effects of radon encounters many challenges and requires a variety of risk communication strategies and approaches. The concern over radon exposure and its health effects may vary according to people's level of knowledge and receptivity. Homeowners in radon-prone areas are usually more informed and have greater concern over those not living in radon-prone areas. The latter group is often found to be resistant to testing. In British Columbia as well as many other parts of the country, some homes have been lying outside of the radon-prone areas have radon levels above the Canadian guideline, which is the reason Health Canada recommends that all homes should be tested. Over the last five years, the Environment Health Program (EHP) of Health Canada in the British Columbia region has been using a variety of different approaches in their radon risk communications through social media, workshops, webinars, public forums, poster contests, radon distribution maps, public inquiries, tradeshows and conference events, and partnership with different jurisdictions and nongovernmental organizations. The valuable lessons learned from these approaches are discussed in this special report.

Volunteers in the earthquake hazard reduction program

USGS Publications Warehouse

Ward, P.L.

1978-01-01

With this in mind, I organized a small workshop for approximately 30 people on February 2 and 3, 1978, in Menlo Park, Calif. the purpose of the meeting was to discuss methods of involving volunteers in a meaningful way in earthquake research and in educating the public about earthquake hazards. The emphasis was on earthquake prediction research, but the discussions covered the whole earthquake hazard reduction program. Representatives attended from the earthquake research community, from groups doing socioeconomic research on earthquake matters, and from a wide variety of organizations who might sponsor volunteers. 

Changing tides: Adaptive monitoring, assessment, and management of pharmaceutical hazards in the environment through time.

PubMed

Gaw, Sally; Brooks, Bryan W

2016-04-01

Pharmaceuticals are ubiquitous contaminants in aquatic ecosystems. Adaptive monitoring, assessment, and management programs will be required to reduce the environmental hazards of pharmaceuticals of concern. Potentially underappreciated factors that drive the environmental dose of pharmaceuticals include regulatory approvals, marketing campaigns, pharmaceutical subsidies and reimbursement schemes, and societal acceptance. Sales data for 5 common antidepressants (duloxetine [Cymbalta], escitalopram [Lexapro], venlafaxine [Effexor], bupropion [Wellbutrin], and sertraline [Zoloft]) in the United States from 2004 to 2008 were modeled to explore how environmental hazards in aquatic ecosystems changed after patents were obtained or expired. Therapeutic hazard ratios for Effexor and Lexapro did not exceed 1; however, the therapeutic hazard ratio for Zoloft declined whereas the therapeutic hazard ratio for Cymbalta increased as a function of patent protection and sale patterns. These changes in therapeutic hazard ratios highlight the importance of considering current and future drivers of pharmaceutical use when prioritizing pharmaceuticals for water quality monitoring programs. When urban systems receiving discharges of environmental contaminants are examined, water quality efforts should identify, prioritize, and select target analytes presently in commerce for effluent monitoring and surveillance. © 2015 SETAC.

Preharvest food safety.

PubMed

Childers, A B; Walsh, B

1996-07-23

Preharvest food safety is essential for the protection of our food supply. The production and transport of livestock and poultry play an integral part in the safety of these food products. The goals of this safety assurance include freedom from pathogenic microorganisms, disease, and parasites, and from potentially harmful residues and physical hazards. Its functions should be based on hazard analysis and critical control points from producer to slaughter plant with emphasis on prevention of identifiable hazards rather than on removal of contaminated products. The production goal is to minimize infection and insure freedom from potentially harmful residues and physical hazards. The marketing goal is control of exposure to pathogens and stress. Both groups should have functional hazard analysis and critical control points management programs which include personnel training and certification of producers. These programs must cover production procedures, chemical usage, feeding, treatment practices, drug usage, assembly and transportation, and animal identification. Plans must use risk assessment principles, and the procedures must be defined. Other elements would include preslaughter certification, environmental protection, control of chemical hazards, live-animal drug-testing procedures, and identification of physical hazards.

Environmental hazards assessment program. Annual report, July 1, 1994--June 30, 1995

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

1995-07-31

This report describes activities and reports on progress for the third year of the DOE grant to support the Environmental Hazards Assessment Program (EHAP). It reports progress against grant objectives and the Program Implementation Plan published at the end of the first year of the grant. As the program has evolved, more projects have been funded and many existing projects have become more complex. Thus, to accomplish better the objectives over the years and retain a solid focus on the total mission, we have reorganized the grant effort from three to five majoe elements: Public and professional outreach; Clinical programs;more » Science programs; Information systems; and, Program management.« less

A Methodology for Multidisciplinary Decision Making for a Surface Combatant Main Engine Selection Problem

DTIC Science & Technology

2014-06-01

nautical miles per hour ONR Office of Naval Research OPC overall propulsive coefficient RS repairable at sea SFC specific fuel consumption SHP shaft...fmSFC SHP hp =  (2.3) Overall Propulsive Coefficient ( OPC ) The overall propulsive coefficient is equal to the ratio between the effective...horsepower (EHP), and the total installed shaft horsepower (SHP) delivered by the main engine [6]. OPC can be determined using the following relationship

CES_EHP_Figure_2

EPA Pesticide Factsheets

The increasing number of chemicals for which SHEDS probabilistic exposure assessment has been performed over the yearsThis dataset is associated with the following publication:Egeghy , P., L. Sheldon, K. Isaacs , H. Ozkaynak, M. Goldsmith, J. Wambaugh , R. Judson , and T. Buckley. Computational Exposure Science: An Emerging Discipline to Support 21st-Century Risk Assessment. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 124(6): 697–702, (2016).

40 CFR 373.3 - Content of notice.

Code of Federal Regulations, 2010 CFR

2010-07-01

... COMMUNITY RIGHT-TO-KNOW PROGRAMS REPORTING HAZARDOUS SUBSTANCE ACTIVITY WHEN SELLING OR TRANSFERRING FEDERAL... information: (a) The name of the hazardous substance; the Chemical Abstracts Services Registry Number (CASRN) where applicable; the regulatory synonym for the hazardous substance, as listed in 40 CFR 302.4, where...

24 CFR 35.130 - Lead hazard information pamphlet.

Code of Federal Regulations, 2010 CFR

2010-04-01

... and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES General Lead-Based Paint Requirements and Definitions for All Programs. § 35.130 Lead hazard information... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Lead hazard information pamphlet...

24 CFR 35.130 - Lead hazard information pamphlet.

Code of Federal Regulations, 2011 CFR

2011-04-01

... and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES General Lead-Based Paint Requirements and Definitions for All Programs. § 35.130 Lead hazard information... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Lead hazard information pamphlet...

24 CFR 35.130 - Lead hazard information pamphlet.

Code of Federal Regulations, 2013 CFR

2013-04-01

... and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES General Lead-Based Paint Requirements and Definitions for All Programs. § 35.130 Lead hazard information... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Lead hazard information pamphlet...

24 CFR 35.130 - Lead hazard information pamphlet.

Code of Federal Regulations, 2012 CFR

2012-04-01

... and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES General Lead-Based Paint Requirements and Definitions for All Programs. § 35.130 Lead hazard information... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Lead hazard information pamphlet...

24 CFR 35.130 - Lead hazard information pamphlet.

Code of Federal Regulations, 2014 CFR

2014-04-01

... and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES General Lead-Based Paint Requirements and Definitions for All Programs. § 35.130 Lead hazard information... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Lead hazard information pamphlet...

77 FR 61825 - Pipeline Safety: Notice of Public Meeting on Pipeline Data

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-11

... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration [Docket ID... program performance measures for gas distribution, gas transmission, and hazardous liquids pipelines. The... distribution pipelines (49 CFR 192.1007(e)), gas transmission pipelines (49 CFR 192.945) and hazardous liquids...

76 FR 62303 - California: Final Authorization of State Hazardous Waste Management Program Revision

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-07

...) Land Disposal Restrictions Phase IV--Treatment Standards for Wood Preserving Wastes, Paperwork... the Carbamate Land Disposal Restrictions; (5) Clarification of Standards for Hazardous Waste LDR...) Emergency Revision of the Land Disposal Restrictions (LDR) Treatment Standards for Listed Hazardous Wastes...

13 CFR 120.174 - Earthquake hazards.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Earthquake hazards. 120.174... Applying to All Business Loans Requirements Imposed Under Other Laws and Orders § 120.174 Earthquake..., the construction must conform with the “National Earthquake Hazards Reduction Program (“NEHRP...

13 CFR 120.174 - Earthquake hazards.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false Earthquake hazards. 120.174... Applying to All Business Loans Requirements Imposed Under Other Laws and Orders § 120.174 Earthquake..., the construction must conform with the “National Earthquake Hazards Reduction Program (“NEHRP...

13 CFR 120.174 - Earthquake hazards.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 13 Business Credit and Assistance 1 2012-01-01 2012-01-01 false Earthquake hazards. 120.174... Applying to All Business Loans Requirements Imposed Under Other Laws and Orders § 120.174 Earthquake..., the construction must conform with the “National Earthquake Hazards Reduction Program (“NEHRP...

13 CFR 120.174 - Earthquake hazards.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Earthquake hazards. 120.174... Applying to All Business Loans Requirements Imposed Under Other Laws and Orders § 120.174 Earthquake..., the construction must conform with the “National Earthquake Hazards Reduction Program (“NEHRP...

Multiple-modality program for standoff detection of roadside hazards

NASA Astrophysics Data System (ADS)

Williams, Kathryn; Middleton, Seth; Close, Ryan; Luke, Robert H.; Suri, Rajiv

2016-05-01

The U.S. Army RDECOM CERDEC Night Vision and Electronic Sensors Directorate (NVESD) is executing a program to assess the performance of a variety of sensor modalities for standoff detection of roadside explosive hazards. The program objective is to identify an optimal sensor or combination of fused sensors to incorporate with autonomous detection algorithms into a system of systems for use in future route clearance operations. This paper provides an overview of the program, including a description of the sensors under consideration, sensor test events, and ongoing data analysis.

Hazard Identification and Risk Assessment in Water Treatment Plant considering Environmental Health and Safety Practice

NASA Astrophysics Data System (ADS)

Falakh, Fajrul; Setiani, Onny

2018-02-01

Water Treatment Plant (WTP) is an important infrastructure to ensure human health and the environment. In its development, aspects of environmental safety and health are of concern. This paper case study was conducted at the Water Treatment Plant Company in Semarang, Central Java, Indonesia. Hazard identification and risk assessment is one part of the occupational safety and health program at the risk management stage. The purpose of this study was to identify potential hazards using hazard identification methods and risk assessment methods. Risk assessment is done using criteria of severity and probability of accident. The results obtained from this risk assessment are 22 potential hazards present in the water purification process. Extreme categories that exist in the risk assessment are leakage of chlorine and industrial fires. Chlorine and fire leakage gets the highest value because its impact threatens many things, such as industrial disasters that could endanger human life and the environment. Control measures undertaken to avoid potential hazards are to apply the use of personal protective equipment, but management will also be better managed in accordance with hazard control hazards, occupational safety and health programs such as issuing work permits, emergency response training is required, Very useful in overcoming potential hazards that have been determined.

49 CFR 107.219 - Processing.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS AND OIL TRANSPORTATION HAZARDOUS MATERIALS PROGRAM... with the disposition of previous applications for waiver of preemption determinations. [Amdt. 107-3, 41...

75 FR 51392 - New York: Incorporation by Reference of State Hazardous Waste Management Program

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-20

... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 272 [EPA-R02-RCRA-2010-0249; FRL-9178-8] New York: Incorporation by Reference of State Hazardous Waste Management Program Correction In rule document 2010-18927 beginning on page 45489 in the issue of Tuesday, August 3, 2010, make the following correction: Appendix A...