Sample records for hell nord-troendelag 20-21

  1. Exhumation Across Hells Canyon and the Arc-continent Boundary of Idaho-Oregon

    NASA Astrophysics Data System (ADS)

    Kahn, M.; Fayon, A. K.; Tikoff, B.

    2015-12-01

    Hells Canyon is located along the Idaho-Oregon border. It is proximal to the Salmon River suture zone, the Cretaceous-age western margin of North America that juxtaposes accreted terranes to the west and cratonic North America to the east. We applied (U-Th)/He zircon and apatite thermochronometry to samples along an EW transect across Hells Canyon. (U-Th)/He zircon and apatite ages record the time at which rocks cool below ~ 200 and 60 °C, respectively, providing information on both the timing and rate at which rocks cooled. Samples were collected with respect to structural position relative to the basal Columbia River basalt flow (Imnaha), dated at ~ 17.4 Ma, with most samples taken <100 m below the contact. Given that all localities were at the Earth's surface - and thus cooled below 60˚C - at ~ 17.4 Ma, the variation in obtained ages are assessed relative to this common datum. The easternmost sites were taken on the western margin of the Idaho batholith at Lava Buttes, ID at ~2,700 m elevation: The (U-Th)/He zircon and apatite ages are 64.9±4.6 Ma and 53.8±4.9 Ma, respectively. The westernmost sites occur in the Wallowa Mountains, Oregon, where the base of the Imnaha flow exists at ~3,000 m: The (U-Th)/He zircon and apatite ages are 136.2±42.8 Ma and 21.7±10.0 Ma. Additionally, the basal basalt contact occurs at ~900 m and ~600 m at the bottom of the Salmon River Canyon and Hells Canyon respectively. The (U-Th)/He zircon and apatite ages are 73.1±14.6 Ma and 20.0±7.4 Ma, respectively, for the Salmon River Canyon and 88.6±2.4 Ma and 3.4±0.6 Ma, respectively, for Hells Canyon. The data indicate that: 1) The western Wallowa (accreted) terrane cooled below ~200 °C prior to the formation of the Idaho batholith; 2) The western side of the Idaho batholith shows a rapid and consistent cooling between ~200 °C and ~60 °C in the Paleogene; and 3) Samples at low elevation in Hells Canyon cooled below 60˚C in the Pliocene, which requires reburial of the rocks

  2. HELLS HOLE ROADLESS AREA, ARIZONA AND NEW MEXICO.

    USGS Publications Warehouse

    Ratte, James C.; Briggs, John P.

    1984-01-01

    The Hells Hole Roadless Area encompasses about 50 sq mi along the Arizona-New Mexico State line. The area was studied and the southeastern part was determined to have a probable mineral-resource potential for the discovery of base- or precious-metal deposits related to igneous intrusions of middle to late Tertiary age. There also is a probable resource potential for porphyry copper mineralization of Laramide age beneath the Tertiary volcanic rocks that cover the area. There is little promise for the occurrence of energy resources in the area. Additional geochemical and petrological studies of the rocks of the Hells Hole volcanic center and modeling of geophysical anomalies are necessary to adequately appraise the mineral-resource potential of the area.

  3. An ATPase-deficient variant of the SNF2 family member HELLS shows altered dynamics at pericentromeric heterochromatin.

    PubMed

    Lungu, Cristiana; Muegge, Kathrin; Jeltsch, Albert; Jurkowska, Renata Z

    2015-05-22

    The HELLS (helicase, lymphoid specific, also known as lymphoid-specific helicase) protein is related to the SNF2 (sucrose non-fermentable 2) family of chromatin remodeling ATPases. It is required for efficient DNA methylation in mammals, particularly at heterochromatin-located repetitive sequences. In this study, we investigated the interaction of HELLS with chromatin and used an ATPase-deficient HELLS variant to address the role of ATP hydrolysis in this process. Chromatin fractionation experiments demonstrated that, in the absence of the ATPase activity, HELLS is retained at the nuclear matrix compartment, defined in part by lamin B1. Microscopy studies revealed a stronger association of the ATPase-deficient mutant with heterochromatin. These results were further supported by fluorescence recovery after photobleaching measurements, which showed that, at heterochromatic sites, wild-type HELLS is very dynamic, with a recovery half-time of 0.8s and a mobile protein fraction of 61%. In contrast, the ATPase-deficient mutant displayed 4.5-s recovery half-time and a reduction in the mobile fraction to 30%. We also present evidence suggesting that, in addition to the ATPase activity, a functional H3K9me3 signaling pathway contributes to an efficient release of HELLS from pericentromeric chromatin. Overall, our results show that a functional ATPase activity is not required for the recruitment of HELLS to heterochromatin, but it is important for the release of the enzyme from these sites. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Mineral Resources of the Hells Canyon Study Area, Wallowa County, Oregon, and Idaho and Adams Counties, Idaho

    USGS Publications Warehouse

    Simmons, George C.; Gualtieri, James L.; Close, Terry J.; Federspiel, Francis E.; Leszcykowski, Andrew M.

    2007-01-01

    Field studies supporting the evaluation of the mineral potential of the Hells Canyon study area were carried out by the U.S. Geological Survey and the U.S. Bureau of Mines in 1974-76 and 1979. The study area includes (1) the Hells Canyon Wilderness; (2) parts of the Snake River, Rapid River, and West Fork Rapid River Wild and Scenic Rivers; (3) lands included in the second Roadless Area Review and Evaluation (RARE II); and (4) part of the Hells Canyon National Recreation Area. The survey is one of a series of studies to appraise the suitability of the area for inclusion in the National Wilderness Preservation System as required by the Wilderness Act of 1964. The spectacular and mineralized area covers nearly 950 mi2 (2,460 km2) in northeast Oregon and west-central Idaho at the junction of the Northern Rocky Mountains and the Columbia Plateau.

  5. Imported fire ants: the ants from hell!

    PubMed

    Freeman, T M

    1994-01-01

    Imported fire ants may certainly be considered the ANTS FROM HELL! This review focuses on both the interesting entomology of fire ants and the important medical characteristics of fire ant stings. They sting and they kill; they destroy; they mate in mid-air; and we may not be able to stop them. However, although they inject extremely potent venom, individuals can prevent secondary infections by leaving the so-called pustules alone and not opening them. Individuals who suffer systemic reactions may receive adequate treatment with the whole body extract immunotherapy.

  6. Escape from Management Hell: 12 Tales of Horror, Humor, and Heroism.

    ERIC Educational Resources Information Center

    Gilbreath, Robert D.

    This book offers a set of stories in which corporate executives demonstrate the folly and futility of their own business practices. In the stories, 12 executives are trying to escape from a hell of their own making. The tales provide insights into the management woes with which people at all levels deal on a daily basis. Topics include: the…

  7. Mercury cycling in the Hells Canyon Complex of the Snake River, Idaho and Oregon

    USGS Publications Warehouse

    Clark, Gregory M.; Naymik, Jesse; Krabbenhoft, David P.; Eagles-Smith, Collin A.; Aiken, George R.; Marvin-DiPasquale, Mark C.; Harris, Reed C.; Myers, Ralph

    2016-07-11

    The Hells Canyon Complex (HCC) is a hydroelectric project built and operated by the Idaho Power Company (IPC) that consists of three dams on the Snake River along the Oregon and Idaho border (fig. 1). The dams have resulted in the creation of Brownlee, Oxbow, and Hells Canyon Reservoirs, which have a combined storage capacity of more than 1.5 million acre-feet and span about 90 miles of the Snake River. The Snake River upstream of and through the HCC historically has been impaired by water-quality issues related to excessive contributions of nutrients, algae, sediment, and other pollutants. In addition, historical data collected since the 1960s from the Snake River and tributaries near the HCC have documented high concentrations of mercury in fish tissue and sediment (Harris and Beals, 2013). Data collected from more recent investigations within the HCC continue to indicate elevated concentrations of mercury and methylmercury in the water column, bottom sediments, and biota (Clark and Maret, 1998; Essig, 2010; Fosness and others, 2013). As a result, Brownlee and Hells Canyon Reservoirs are listed as impaired for mercury by the State of Idaho, and the Snake River from the Oregon and Idaho border through the HCC downstream to the Oregon and Washington border is listed as impaired for mercury by the State of Oregon.

  8. 20 CFR 355.21 - Discovery.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true Discovery. 355.21 Section 355.21 Employees... UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for inspection and copying; (2) Requests...

  9. 20 CFR 355.21 - Discovery.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false Discovery. 355.21 Section 355.21 Employees... UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for inspection and copying; (2) Requests...

  10. 20 CFR 355.21 - Discovery.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false Discovery. 355.21 Section 355.21 Employees... UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for inspection and copying; (2) Requests...

  11. 20 CFR 355.21 - Discovery.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true Discovery. 355.21 Section 355.21 Employees... UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for inspection and copying; (2) Requests...

  12. 20 CFR 355.21 - Discovery.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Discovery. 355.21 Section 355.21 Employees... UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for inspection and copying; (2) Requests...

  13. Visual resource inventory and Imnaha Valley study: Hells Canyon National Recreation Area

    Treesearch

    David H. Blau; Michael C. Bowie; Frank Hunsaker

    1979-01-01

    Hells Canyon National Recreation Area was established by an Act of Congress in December 1975. At that time, the U.S. Forest Service, which administers most of the land included, was given the responsibility of developing a Comprehensive Management Plan for the NRA within five years. In order to minimize future visual degradation, the Forest Service planning team for...

  14. 21 CFR 606.20 - Personnel.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Personnel. 606.20 Section 606.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS CURRENT GOOD MANUFACTURING PRACTICE FOR BLOOD AND BLOOD COMPONENTS Organization and Personnel § 606.20...

  15. Seismic profile analysis of sediment deposits in Brownlee and Hells Canyon Reservoirs near Cambridge, Idaho

    USGS Publications Warehouse

    Flocks, James; Kelso, Kyle; Fosness, Ryan; Welcker, Chris

    2014-01-01

    The U.S. Geological Survey (USGS) St. Petersburg Coastal and Marine Science Center, in cooperation with the USGS Idaho Water Science Center and the Idaho Power Company, collected high-resolution seismic reflection data in the Brownlee and Hells Canyon Reservoirs, in March of 2013.These reservoirs are located along the Snake River, and were constructed in 1958 (Brownlee) and 1967 (Hells Canyon). The purpose of the survey was to gain a better understanding of sediment accumulation within the reservoirs since their construction. The chirp system used in the survey was an EdgeTech Geo-Star Full Spectrum Sub-Bottom (FSSB) system coupled with an SB-424 towfish with a frequency range of 4 to 24 kHz. Approximately 325 kilometers of chirp data were collected, with water depths ranging from 0-90 meters. These reservoirs are characterized by very steep rock valley walls, very low flow rates, and minimal sediment input into the system. Sediments deposited in the reservoirs are characterized as highly fluid clays. Since the acoustic signal was not able to penetrate the rock substrate, only the thin veneer of these recent deposits were imaged. Results from the seismic survey indicate that throughout both of the Brownlee and Hells Canyon reservoirs the accumulation of sediments ranged from 0 to 2.5 m, with an average of 0.5 m. Areas of above average sediment accumulation may be related to lower slope, longer flooding history, and proximity to fluvial sources.

  16. 21 CFR 123.20 - General.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false General. 123.20 Section 123.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION FISH AND FISHERY PRODUCTS Raw Molluscan Shellfish § 123.20 General. This subpart augments subpart...

  17. 21 CFR 123.20 - General.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false General. 123.20 Section 123.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION FISH AND FISHERY PRODUCTS Raw Molluscan Shellfish § 123.20 General. This subpart augments subpart...

  18. 21 CFR 808.20 - Application.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Application. 808.20 Section 808.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES....20 Application. (a) Any State or political subdivision may apply to the Food and Drug Administration...

  19. 21 CFR 808.20 - Application.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Application. 808.20 Section 808.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES....20 Application. (a) Any State or political subdivision may apply to the Food and Drug Administration...

  20. 21 CFR 20.103 - Correspondence.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Correspondence. 20.103 Section 20.103 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.103 Correspondence. (a) All correspondence to and from...

  1. 21 CFR 120.20 - General.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false General. 120.20 Section 120.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION HAZARD ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS Pathogen Reduction § 120.20 General...

  2. 21 CFR 120.20 - General.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false General. 120.20 Section 120.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION HAZARD ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS Pathogen Reduction § 120.20 General...

  3. 21 CFR 120.20 - General.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false General. 120.20 Section 120.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION HAZARD ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS Pathogen Reduction § 120.20 General...

  4. 21 CFR 120.20 - General.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false General. 120.20 Section 120.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION HAZARD ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS Pathogen Reduction § 120.20 General...

  5. 21 CFR 120.20 - General.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false General. 120.20 Section 120.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION HAZARD ANALYSIS AND CRITICAL CONTROL POINT (HACCP) SYSTEMS Pathogen Reduction § 120.20 General...

  6. The NordICC Study: Rationale and design of a randomized trial on colonoscopy screening for colorectal cancer

    PubMed Central

    F.Kaminski, Michal; Bretthauer, Michael; Zauber, Ann G.; Kuipers, Ernst J.; Adami, Hans-Olov; van Ballegooijen, Marjolein; Regula, Jaroslaw; van Leerdam, Monique; Stefansson, Tryggvi; Påhlman, Lars; Dekker, Evelien; Hernán, Miguel A.; Garborg, Kjetil; Hoff, Geir

    2017-01-01

    Background While colonoscopy screening is widely used in several European countries and the United States, no randomised trials exist to quantify its benefits. The Nordic-European Initiative on Colorectal Cancer (NordICC) is a multinational, randomized controlled trial aiming at investigating the effect of colonoscopy screening on CRC incidence and mortality. This paper describes the rationale and design of the NordICC trial. Material and methods Men and women age 55 to 64 years are drawn from the population registries in the participating countries and randomly assigned to either once-only colonoscopy screening with removal of all detected lesions, or no screening (standard of care in the trial regions). All individuals are followed for 15 years after inclusion using dedicated national registries. Results The primary endpoints of the trial are cumulative CRC-specific death and CRC incidence during 15 years of follow up. We hypothesize a 50% CRC mortality-reducing efficacy of the colonoscopy intervention and predict 50% compliance, yielding a 25% mortality reduction among those invited to screening. For 90% power and a two-sided alpha level of 0.05, using a 2:1 randomisation, 45,600 individuals will be randomised to control, and 22,800 individuals to the colonoscopy group. Interim analyses of the effect of colonoscopy on CRC incidence and mortality will be performed at 10 years follow-up. Conclusions The aim of the NordICC trial is to quantify the effectiveness of population-based colonoscopy screening. This will allow development of evidence-based guidelines for CRC screening in the general population. PMID:22723185

  7. 21 CFR 1005.20 - Hearing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Hearing. 1005.20 Section 1005.20 Food and Drugs... IMPORTATION OF ELECTRONIC PRODUCTS Bonding and Compliance Procedures § 1005.20 Hearing. (a) If, from an... is not submitted at or prior to the hearing, the Secretary may allow a reasonable time for filing...

  8. 21 CFR 808.20 - Application.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Application. 808.20 Section 808.20 Food and Drugs....20 Application. (a) Any State or political subdivision may apply to the Food and Drug Administration... effect of law. However, an application for exemption may be submitted before the effective date of the...

  9. With Dante in Hell on 9/11: "That Day We Read No Further"

    ERIC Educational Resources Information Center

    Rosenstein, Roy

    2015-01-01

    In this article, Roy Rosenstein shares the events that occurred during his first day of teaching the Dante and Medieval Culture course in the fall semester of 2001 at the American University of Paris (AUP). On, September 11, 2001, immediately following Rosenstein's opening statement of "Welcome to hell," the class was alerted to the…

  10. Socioeconomic inequalities in dental services utilisation in a Norwegian county: the third Nord-Trondelag Health Survey.

    PubMed

    Vikum, Eirik; Krokstad, Steinar; Holst, Dorthe; Westin, Steinar

    2012-11-01

    To assess the level of socioeconomic inequity in dental care utilisation in Norway and enable comparison with recent international comparative studies. We studied dental care utilisation among 17,136 men and 21,414 women in the third Nord-Trøndelag Health Survey (2006-08). Respondents aged 20 years and above were included in the study, and analyses were also performed within subgroups of age and gender (20-39, 40-59, and ≥60 years). Income-related horizontal inequity was estimated by means of concentration indices. Education-related inequity was estimated as relative risks. We found consistent pro-rich income inequity among men and women of all ages. The level of income inequity was highest among men and women ≥60 years, and in this group the income gradient was steepest between the poorest and the middle quintiles. Pro-educated inequity was found exclusively among men and women ≥60 years. General attendance was high (77%). The overall level of income-related inequity in dental services utilisation was low compared to other European countries as reported in two recent international studies of socioeconomic inequalities in dental care utilisation. Pro-rich and pro-educated inequity is a public health challenge mainly in the older part of the population.

  11. Teaching Religion in Public Schools: Review of Warren A. Nord, "Does God Make a Difference?"

    ERIC Educational Resources Information Center

    Feinberg, Walter

    2013-01-01

    In this review of Warren Nord's "Does God Make a Difference? Taking Religion Seriously in Our Schools and Universities," Walter Feinberg provides a detailed analysis of Nord's argument that the study of religion should be constitutionally mandated as a corrective to the overwhelmingly secular course of study offered in…

  12. 49 CFR 392.20-392.21 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false [Reserved] 392.20-392.21 Section 392.20-392.21 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL MOTOR CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS DRIVING OF COMMERCIAL MOTOR...

  13. 21 CFR 1250.20 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Applicability. 1250.20 Section 1250.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION INTERSTATE CONVEYANCE...

  14. 21 CFR 226.20 - Buildings.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Buildings. 226.20 Section 226.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL... insecticides, fungicides, rodenticides, or other pesticides or their components unless such materials are...

  15. 21 CFR 226.20 - Buildings.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Buildings. 226.20 Section 226.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR TYPE A MEDICATED ARTICLES Construction and Maintenance of...

  16. 21 CFR 1250.20 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Applicability. 1250.20 Section 1250.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS UNDER CERTAIN OTHER ACTS ADMINISTERED BY THE FOOD AND DRUG ADMINISTRATION INTERSTATE CONVEYANCE...

  17. Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo)

    PubMed Central

    Wahlin, Karl; Artama, Miia; Brusselaers, Nele; Färkkilä, Martti; Lynge, Elsebeth; Mattsson, Fredrik; Pukkala, Eero; Romundstad, Pål; Tryggvadóttir, Laufey; von Euler-Chelpin, My; Lagergren, Jesper

    2017-01-01

    Purpose To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery with those who have not regarding risk of cancers, other diseases and mortality. Participants Included were individuals with a GORD diagnosis recorded in any of the nationwide patient registries in the Nordic countries (Denmark, Finland, Iceland, Norway and Sweden) in 1964–2014 (with various start and end years in different countries). Data regarding cancer, other diseases and mortality were retrieved from the nationwide registries for cancer, patients and causes of death, respectively. Findings to date The NordASCo includes 945 153 individuals with a diagnosis of GORD. Of these, 48 433 (5.1%) have undergone primary antireflux surgery. Median age at primary antireflux surgery ranged from 47 to 52 years in the different countries. The coding practices of GORD seem to have differed between the Nordic countries. Future plans The NordASCo will initially be used to analyse the risk of developing known or potential GORD-related cancers, that is, tumours of the oesophagus, stomach, larynx, pharynx and lung, and to evaluate the mortality in the short-term and long-term perspectives. Additionally, the cohort will be used to evaluate the risk of non-malignant respiratory conditions that might be caused by aspiration of gastric contents. PMID:28600380

  18. 45 CFR 400.20-400.21 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false [Reserved] 400.20-400.21 Section 400.20-400.21 Public Welfare Regulations Relating to Public Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM General...

  19. 21 CFR 1250.20 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Applicability. 1250.20 Section 1250.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS... conveyances engaged in interstate traffic shall comply with the requirements prescribed in this subpart and...

  20. 21 CFR 1250.20 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Applicability. 1250.20 Section 1250.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS... conveyances engaged in interstate traffic shall comply with the requirements prescribed in this subpart and...

  1. 21 CFR 1250.20 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Applicability. 1250.20 Section 1250.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) REGULATIONS... conveyances engaged in interstate traffic shall comply with the requirements prescribed in this subpart and...

  2. 21 CFR 600.20 - Inspectors.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... the Food and Drug Administration having special knowledge of the methods used in the manufacture and... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Inspectors. 600.20 Section 600.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS BIOLOGICAL...

  3. 21 CFR 600.20 - Inspectors.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... the Food and Drug Administration having special knowledge of the methods used in the manufacture and... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Inspectors. 600.20 Section 600.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS BIOLOGICAL...

  4. 21 CFR 600.20 - Inspectors.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... the Food and Drug Administration having special knowledge of the methods used in the manufacture and... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Inspectors. 600.20 Section 600.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS BIOLOGICAL...

  5. 21 CFR 106.20 - Ingredient control.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Ingredient control. 106.20 Section 106.20 Food and... CONSUMPTION INFANT FORMULA QUALITY CONTROL PROCEDURES Quality Control Procedures for Assuring Nutrient Content of Infant Formulas § 106.20 Ingredient control. (a) Except as provided in § 106.20(b), no analysis...

  6. 21 CFR 106.20 - Ingredient control.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Ingredient control. 106.20 Section 106.20 Food and... CONSUMPTION INFANT FORMULA QUALITY CONTROL PROCEDURES Quality Control Procedures for Assuring Nutrient Content of Infant Formulas § 106.20 Ingredient control. (a) Except as provided in § 106.20(b), no analysis...

  7. 21 CFR 106.20 - Ingredient control.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Ingredient control. 106.20 Section 106.20 Food and... CONSUMPTION INFANT FORMULA QUALITY CONTROL PROCEDURES Quality Control Procedures for Assuring Nutrient Content of Infant Formulas § 106.20 Ingredient control. (a) Except as provided in § 106.20(b), no analysis...

  8. 21 CFR 820.20 - Management responsibility.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Management responsibility. 820.20 Section 820.20...) MEDICAL DEVICES QUALITY SYSTEM REGULATION Quality System Requirements § 820.20 Management responsibility. (a) Quality policy. Management with executive responsibility shall establish its policy and...

  9. 21 CFR 820.20 - Management responsibility.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Management responsibility. 820.20 Section 820.20...) MEDICAL DEVICES QUALITY SYSTEM REGULATION Quality System Requirements § 820.20 Management responsibility. (a) Quality policy. Management with executive responsibility shall establish its policy and...

  10. 21 CFR 820.20 - Management responsibility.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Management responsibility. 820.20 Section 820.20...) MEDICAL DEVICES QUALITY SYSTEM REGULATION Quality System Requirements § 820.20 Management responsibility. (a) Quality policy. Management with executive responsibility shall establish its policy and...

  11. 21 CFR 820.20 - Management responsibility.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Management responsibility. 820.20 Section 820.20...) MEDICAL DEVICES QUALITY SYSTEM REGULATION Quality System Requirements § 820.20 Management responsibility. (a) Quality policy. Management with executive responsibility shall establish its policy and...

  12. 21 CFR 820.20 - Management responsibility.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Management responsibility. 820.20 Section 820.20...) MEDICAL DEVICES QUALITY SYSTEM REGULATION Quality System Requirements § 820.20 Management responsibility. (a) Quality policy. Management with executive responsibility shall establish its policy and...

  13. 21 CFR 600.20 - Inspectors.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Inspectors. 600.20 Section 600.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS BIOLOGICAL... control of products and designated for such purposes by the Commissioner of Food and Drugs, or by any...

  14. 21 CFR 600.20 - Inspectors.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Inspectors. 600.20 Section 600.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) BIOLOGICS BIOLOGICAL... control of products and designated for such purposes by the Commissioner of Food and Drugs, or by any...

  15. Prevalence and associated factors of DSM-V insomnia in Norway: the Nord-Trøndelag Health Study (HUNT 3).

    PubMed

    Uhlig, Benjamin Langsæter; Sand, Trond; Odegård, Siv Steinsmo; Hagen, Knut

    2014-06-01

    Many studies have assessed the prevalence of insomnia, but the influence of non-participants has largely been ignored. The objective of the present study was to estimate the prevalence and associated factors of insomnia in a large adult population using DSM-V (diagnostic and statistical manual of mental disorders, 5th ed.) criteria, also taking non-participants into account. This cross-sectional study used data from a questionnaire in The Nord-Trøndelag Health Study (HUNT 3) performed in 2006-2008, and a subsequent non-participant study. The total adult population (n=93,860 aged > or =20 years) of Nord-Trøndelag County, Norway, was invited. Of these, 40,535 responded to the insomnia questionnaire. Among 42,024 eligible non-participants, 6918 (17%) responded to two insomnia questions. Insomnia was diagnosed by applying modified DSM-V criteria. The age-adjusted insomnia prevalence was estimated using the age distribution of all adult inhabitants of Nord-Trøndelag. Supplementary prevalence data were estimated by extrapolating data from the non-participant study. Additionally, the association between insomnia and self-reported health was estimated, adjusting for known confounders. The total age-adjusted prevalence of insomnia was 7.1% (95% confidence interval [CI], 6.9-7.4) (8.6% for women, 5.5% for men). Adjusting for non-participants, the prevalence estimate changed to 7.9% (95% CI, 7.3-8.6) (9.4% for women, 6.4% for men). Insomnia was more than eight times more likely (OR, 8.3; 95% CI, 6.2-11.1) among individuals with very poor versus very good self-reported health, adjusting for age, gender, employment status, chronic musculoskeletal complaints, anxiety and depression. The adjusted insomnia prevalence estimate in Nord-Trøndelag was 7.9%. Insomnia was strongly associated with poor self-reported health. Copyright © 2014 Elsevier B.V. All rights reserved.

  16. Politicians, Patriots and Plotters: Unlikely Debates Occasioned by Maximilian Hell's Venus Transit Expedition of 1769

    NASA Astrophysics Data System (ADS)

    Kontler, Laszlo

    2013-05-01

    This paper discusses the cultural and political contexts and reception of the most important by-product of Maximilian Hell's famous Venus transit expedition of 1768-69, the Demonstratio. Idioma Ungarorum et Lapponum idem esse (1770) by Hell's associate Janos Sajnovics. Now considered a landmark in Finno-Ugrian linguistics, the Demonstratio addressed an academic subject that was at that time almost destined to be caught up in an ideological battlefield defined by the shifting relationship between the Habsburg government, the Society of Jesus, and the Hungarian nobility. The "enlightened absolutist" policies of the former aimed at consolidating the Habsburg monarchy as an empire, at the expense of privileged groups, including religious orders as well as the noble estates. In the situation created by the 1773 suppression of the Jesuit order (a signal of declining patronage from the dynasty), the growing preoccupation on the part of ex-Jesuits like Hell and Sajnovics with "things Hungarian" could have been part of an attempt to re-situate themselves on the Central European map of learning. At the same time, the founding document of this interest, the Demonstratio, evoked violent protests from the other target of Habsburg policies, the Hungarian nobility, because its basic assumptions - the kinship of the Hungarian and the Sami (Lappian) language - potentially undermined the noble ideology of social exclusiveness, established on the alleged "Scythian" ancestry of Hungarians. By exploring the complex motives, intentions, reactions and responses of the chief agents in this story, it is possible to highlight the extra-scientific constraints and facilitators for the practice of knowledge in late eighteenth century Central Europe.

  17. Cohort profile: the Nordic Antireflux Surgery Cohort (NordASCo).

    PubMed

    Maret-Ouda, John; Wahlin, Karl; Artama, Miia; Brusselaers, Nele; Färkkilä, Martti; Lynge, Elsebeth; Mattsson, Fredrik; Pukkala, Eero; Romundstad, Pål; Tryggvadóttir, Laufey; Euler-Chelpin, My von; Lagergren, Jesper

    2017-06-08

    To describe a newly created all-Nordic cohort of patients with gastro-oesophageal reflux disease (GORD), entitled the Nordic Antireflux Surgery Cohort (NordASCo), which will be used to compare participants having undergone antireflux surgery with those who have not regarding risk of cancers, other diseases and mortality. Included were individuals with a GORD diagnosis recorded in any of the nationwide patient registries in the Nordic countries (Denmark, Finland, Iceland, Norway and Sweden) in 1964-2014 (with various start and end years in different countries). Data regarding cancer, other diseases and mortality were retrieved from the nationwide registries for cancer, patients and causes of death, respectively. The NordASCo includes 945 153 individuals with a diagnosis of GORD. Of these, 48 433 (5.1%) have undergone primary antireflux surgery. Median age at primary antireflux surgery ranged from 47 to 52 years in the different countries. The coding practices of GORD seem to have differed between the Nordic countries. The NordASCo will initially be used to analyse the risk of developing known or potential GORD-related cancers, that is, tumours of the oesophagus, stomach, larynx, pharynx and lung, and to evaluate the mortality in the short-term and long-term perspectives. Additionally, the cohort will be used to evaluate the risk of non-malignant respiratory conditions that might be caused by aspiration of gastric contents. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  18. 20 CFR 656.21 - Supervised recruitment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Supervised recruitment. 656.21 Section 656.21... Supervised recruitment. (a) Supervised recruitment. Where the Certifying Officer determines it appropriate, post-filing supervised recruitment may be required of the employer for the pending application or...

  19. 21 CFR 203.20 - Sales restrictions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Sales restrictions. 203.20 Section 203.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL PRESCRIPTION DRUG MARKETING Sales Restrictions § 203.20 Sales restrictions. Except as provided in § 203.22 or...

  20. 21 CFR 26.20 - Alert system.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Alert system. 26.20 Section 26.20 Food and Drugs... PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT REPORTS, AND CERTAIN... Provisions for Pharmaceutical Good Manufacturing Practices § 26.20 Alert system. (a) The details of an alert...

  1. 21 CFR 26.20 - Alert system.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Alert system. 26.20 Section 26.20 Food and Drugs... PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT REPORTS, AND CERTAIN... Provisions for Pharmaceutical Good Manufacturing Practices § 26.20 Alert system. (a) The details of an alert...

  2. 21 CFR 355.20 - Packaging conditions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... HUMAN USE ANTICARIES DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 355.20 Packaging conditions. (a) Package size limitation. Due to the toxicity associated with fluoride active ingredients, the... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Packaging conditions. 355.20 Section 355.20 Food...

  3. 21 CFR 203.20 - Sales restrictions.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Sales restrictions. 203.20 Section 203.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL PRESCRIPTION DRUG MARKETING Sales Restrictions § 203.20 Sales restrictions. Except as provided in § 203.22 or...

  4. 21 CFR 203.20 - Sales restrictions.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 4 2013-04-01 2013-04-01 false Sales restrictions. 203.20 Section 203.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL PRESCRIPTION DRUG MARKETING Sales Restrictions § 203.20 Sales restrictions. Except as provided in § 203.22 or...

  5. 21 CFR 203.20 - Sales restrictions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Sales restrictions. 203.20 Section 203.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL PRESCRIPTION DRUG MARKETING Sales Restrictions § 203.20 Sales restrictions. Except as provided in § 203.22 or...

  6. 21 CFR 203.20 - Sales restrictions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Sales restrictions. 203.20 Section 203.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL PRESCRIPTION DRUG MARKETING Sales Restrictions § 203.20 Sales restrictions. Except as provided in § 203.22 or...

  7. 21 CFR 26.20 - Alert system.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... PHARMACEUTICAL GOOD MANUFACTURING PRACTICE REPORTS, MEDICAL DEVICE QUALITY SYSTEM AUDIT REPORTS, AND CERTAIN... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Alert system. 26.20 Section 26.20 Food and Drugs... Provisions for Pharmaceutical Good Manufacturing Practices § 26.20 Alert system. (a) The details of an alert...

  8. Tiffany Diamonds and Classical Music as Influences on the Performance of "Don Juan in Hell".

    ERIC Educational Resources Information Center

    Johnson, Jim

    This paper analyzes Paul Gregory's 1951 production of "Don Juan in Hell," now considered to be a seminal work in the development of professional and educational readers theatre. The paper contends that the production, which presented a nondramatic work without the usual emphasis on design and spectacle, forced a reexamination of the role…

  9. 21 CFR 106.20 - Ingredient control.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Ingredient control. 106.20 Section 106.20 Food and... CONSUMPTION INFANT FORMULA QUALITY CONTROL PROCEDURES (Eff. until 7-10-14) Quality Control Procedures for Assuring Nutrient Content of Infant Formulas § 106.20 Ingredient control. (a) Except as provided in § 106...

  10. 21 CFR 20.41 - Time limitations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Time limitations. 20.41 Section 20.41 Food and... Procedures and Fees § 20.41 Time limitations. (a) All time limitations prescribed pursuant to this section shall begin as of the time at which a request for records is logged in by the Freedom of Information...

  11. 21 CFR 20.41 - Time limitations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Time limitations. 20.41 Section 20.41 Food and... Procedures and Fees § 20.41 Time limitations. (a) All time limitations prescribed pursuant to this section shall begin as of the time at which a request for records is logged in by the Division of Freedom of...

  12. 21 CFR 20.41 - Time limitations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Time limitations. 20.41 Section 20.41 Food and... Procedures and Fees § 20.41 Time limitations. (a) All time limitations prescribed pursuant to this section shall begin as of the time at which a request for records is logged in by the Division of Freedom of...

  13. 21 CFR 21.20 - Procedures for notice of Food and Drug Administration Privacy Act Record Systems.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Administration Privacy Act Record Systems. 21.20 Section 21.20 Food and Drugs FOOD AND DRUG ADMINISTRATION... Act Record Systems § 21.20 Procedures for notice of Food and Drug Administration Privacy Act Record... of each year a notice concerning each Privacy Act Record System as defined in § 21.3(c) that is not...

  14. 21 CFR 21.20 - Procedures for notice of Food and Drug Administration Privacy Act Record Systems.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Administration Privacy Act Record Systems. 21.20 Section 21.20 Food and Drugs FOOD AND DRUG ADMINISTRATION... Act Record Systems § 21.20 Procedures for notice of Food and Drug Administration Privacy Act Record... of each year a notice concerning each Privacy Act Record System as defined in § 21.3(c) that is not...

  15. 21 CFR 21.20 - Procedures for notice of Food and Drug Administration Privacy Act Record Systems.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Administration Privacy Act Record Systems. 21.20 Section 21.20 Food and Drugs FOOD AND DRUG ADMINISTRATION... Act Record Systems § 21.20 Procedures for notice of Food and Drug Administration Privacy Act Record... of each year a notice concerning each Privacy Act Record System as defined in § 21.3(c) that is not...

  16. 21 CFR 21.20 - Procedures for notice of Food and Drug Administration Privacy Act Record Systems.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Administration Privacy Act Record Systems. 21.20 Section 21.20 Food and Drugs FOOD AND DRUG ADMINISTRATION... Act Record Systems § 21.20 Procedures for notice of Food and Drug Administration Privacy Act Record... of each year a notice concerning each Privacy Act Record System as defined in § 21.3(c) that is not...

  17. 20 CFR 606.21 - Criteria for cap.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Criteria for cap. 606.21 Section 606.21 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR TAX CREDITS UNDER THE... Reduction § 606.21 Criteria for cap. (a) Reduction in unemployment tax effort. (1) For purposes of paragraph...

  18. Dinosaur Census Reveals Abundant Tyrannosaurus and Rare Ontogenetic Stages in the Upper Cretaceous Hell Creek Formation (Maastrichtian), Montana, USA

    PubMed Central

    Horner, John R.; Goodwin, Mark B.; Myhrvold, Nathan

    2011-01-01

    Background A dinosaur census recorded during the Hell Creek Project (1999–2009) incorporates multiple lines of evidence from geography, taphohistory, stratigraphy, phylogeny and ontogeny to investigate the relative abundance of large dinosaurs preserved in the Upper Cretaceous Hell Creek Formation of northeastern Montana, USA. Overall, the dinosaur skeletal assemblages in the Hell Creek Formation (excluding lag-influenced records) consist primarily of subadult or small adult size individuals. Small juveniles and large adults are both extremely rare, whereas subadult individuals are relatively common. We propose that mature individuals of at least some dinosaur taxa either lived in a separate geographic locale analogous to younger individuals inhabiting an upland environment where sedimentation rates were relatively less, or these taxa experienced high mortality before reaching terminal size where late stage and often extreme cranial morphology is expressed. Methodology/Principal Findings Tyrannosaurus skeletons are as abundant as Edmontosaurus, an herbivore, in the upper Hell Creek Formation and nearly twice as common in the lower third of the formation. Smaller, predatory dinosaurs (e.g., Troodon and dromaeosaurids) are primarily represented by teeth found in microvertebrate localities and their skeletons or identifiable lag specimens were conspicuously absent. This relative abundance suggests Tyrannosaurus was not a typical predator and likely benefited from much wider food choice opportunities than exclusively live prey and/or specific taxa. Tyrannosaurus adults may not have competed with Tyrannosaurus juveniles if the potential for selecting carrion increased with size during ontogeny. Conclusions/Significance Triceratops is the most common dinosaur and isolated skulls contribute to a significant portion of this census. Associated specimens of Triceratops consisting of both cranial and postcranial elements remain relatively rare. This rarity may be explained

  19. 34 CFR 21.20 - Types of eligible applicants.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Types of eligible applicants. 21.20 Section 21.20 Education Office of the Secretary, Department of Education EQUAL ACCESS TO JUSTICE How Is Eligibility... employees. (d) A cooperative association— (1) As defined in section 15(a) of the Agricultural Marketing Act...

  20. Analysis of modeling aircraft noise with the Nord2000 noise model

    DOT National Transportation Integrated Search

    2012-10-31

    This report provides comparisons between AEDT/INM and the Nord 2000 Noise Models for the following parameters: ground type, simple terrain (downward slope, upward slope, hill), temperature and humidity, temperature gradients (positive and negative), ...

  1. 21 CFR 21.20 - Procedures for notice of Food and Drug Administration Privacy Act Record Systems.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Administration Privacy Act Record Systems. 21.20 Section 21.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROTECTION OF PRIVACY Food and Drug Administration Privacy Act Record Systems § 21.20 Procedures for notice of Food and Drug Administration Privacy Act Record...

  2. 21 CFR 355.20 - Packaging conditions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Packaging conditions. 355.20 Section 355.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR... accord with § 355.60. (b) Tight container packaging. To minimize moisture contamination, all fluoride...

  3. 21 CFR 20.101 - Administrative enforcement records.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Administrative enforcement records. 20.101 Section 20.101 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.101 Administrative enforcement...

  4. 21 CFR 20.117 - New drug information.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false New drug information. 20.117 Section 20.117 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.117 New drug information. (a) The following...

  5. 21 CFR 20.117 - New drug information.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false New drug information. 20.117 Section 20.117 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.117 New drug information. (a) The following...

  6. 21 CFR 20.90 - Disclosure to contractors.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... INFORMATION Limitations on Exemptions § 20.90 Disclosure to contractors. (a) Data and information otherwise... employees; (4) Limitations on reproduction, transmission, and disclosure of the data and information; (5) A... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Disclosure to contractors. 20.90 Section 20.90...

  7. 21 CFR 20.90 - Disclosure to contractors.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... INFORMATION Limitations on Exemptions § 20.90 Disclosure to contractors. (a) Data and information otherwise... employees; (4) Limitations on reproduction, transmission, and disclosure of the data and information; (5) A... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Disclosure to contractors. 20.90 Section 20.90...

  8. 21 CFR 20.102 - Court enforcement records.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Court enforcement records. 20.102 Section 20.102 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.102 Court enforcement records. (a) All records...

  9. 21 CFR 20.117 - New drug information.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false New drug information. 20.117 Section 20.117 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.117 New drug information. (a) The following...

  10. 21 CFR 20.118 - Advisory committee records.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Advisory committee records. 20.118 Section 20.118 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.118 Advisory committee records. All advisory...

  11. 21 CFR 20.90 - Disclosure to contractors.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Disclosure to contractors. 20.90 Section 20.90... INFORMATION Limitations on Exemptions § 20.90 Disclosure to contractors. (a) Data and information otherwise exempt from public disclosure may be disclosed to contractors with the Food and Drug Administration and...

  12. 21 CFR 20.117 - New drug information.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false New drug information. 20.117 Section 20.117 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.117 New drug information. (a) The following...

  13. Coulomb excitation of radioactive 20, 21Na

    NASA Astrophysics Data System (ADS)

    Schumaker, M. A.; Cline, D.; Hackman, G.; Pearson, C.; Svensson, C. E.; Wu, C. Y.; Andreyev, A.; Austin, R. A. E.; Ball, G. C.; Bandyopadhyay, D.; Becker, J. A.; Boston, A. J.; Boston, H. C.; Buchmann, L.; Churchman, R.; Cifarelli, F.; Cooper, R. J.; Cross, D. S.; Dashdorj, D.; Demand, G. A.; Dimmock, M. R.; Drake, T. E.; Finlay, P.; Gallant, A. T.; Garrett, P. E.; Green, K. L.; Grint, A. N.; Grinyer, G. F.; Harkness, L. J.; Hayes, A. B.; Kanungo, R.; Lisetskiy, A. F.; Leach, K. G.; Lee, G.; Maharaj, R.; Martin, J.-P.; Moisan, F.; Morton, A. C.; Mythili, S.; Nelson, L.; Newman, O.; Nolan, P. J.; Orce, J. N.; Padilla-Rodal, E.; Phillips, A. A.; Porter-Peden, M.; Ressler, J. J.; Roy, R.; Ruiz, C.; Sarazin, F.; Scraggs, D. P.; Waddington, J. C.; Wan, J. M.; Whitbeck, A.; Williams, S. J.; Wong, J.

    2009-12-01

    The low-energy structures of the radioactive nuclei 20, 21Na have been examined using Coulomb excitation at the TRIUMF-ISAC radioactive ion beam facility. Beams of ˜ 5×106 ions/s were accelerated to 1.7MeV/A and Coulomb excited in a 0.5mg/cm^2 natTi target. Two TIGRESS HPGe clover detectors perpendicular to the beam axis were used for γ -ray detection, while scattered nuclei were observed by the Si detector BAMBINO. For 21Na , Coulomb excitation from the 3/2+ ground state to the first excited 5/2+ state was observed, while for 20Na , Coulomb excitation was observed from the 2+ ground state to the first excited 3+ and 4+ states. For both beams, B ( λ L) values were determined using the 2+ rightarrow 0+ de-excitation in 48Ti as a reference. The resulting B( E2) ↓ value for 21Na is 137±9 e^2fm^4, while the resulting B( λ L) ↓ values for 20Na are 55±6 e^2fm^4 for the 3+ rightarrow 2+ , 35.7±5.7 e^2 fm^4 for the 4+ rightarrow 2+ , and 0.154±0.030 μ_ N^2 for the 4+ rightarrow 3+ transitions. This analysis significantly improves the measurement of the 21Na B( E2) value, and provides the first experimental determination of B( λ L) values for the proton dripline nucleus 20Na .-1

  14. 21 CFR 660.20 - Blood Grouping Reagent.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Blood Grouping Reagent. 660.20 Section 660.20 Food... ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Blood Grouping Reagent § 660.20 Blood Grouping Reagent. (a) Proper name and definition. The proper name of this product shall be Blood Grouping...

  15. 21 CFR 660.20 - Blood Grouping Reagent.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Blood Grouping Reagent. 660.20 Section 660.20 Food... ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Blood Grouping Reagent § 660.20 Blood Grouping Reagent. (a) Proper name and definition. The proper name of this product shall be Blood Grouping...

  16. 21 CFR 660.20 - Blood Grouping Reagent.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Blood Grouping Reagent. 660.20 Section 660.20 Food... ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Blood Grouping Reagent § 660.20 Blood Grouping Reagent. (a) Proper name and definition. The proper name of this product shall be Blood Grouping...

  17. 21 CFR 660.20 - Blood Grouping Reagent.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Blood Grouping Reagent. 660.20 Section 660.20 Food... ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Blood Grouping Reagent § 660.20 Blood Grouping Reagent. (a) Proper name and definition. The proper name of this product shall be Blood Grouping...

  18. 21 CFR 660.20 - Blood Grouping Reagent.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Blood Grouping Reagent. 660.20 Section 660.20 Food... ADDITIONAL STANDARDS FOR DIAGNOSTIC SUBSTANCES FOR LABORATORY TESTS Blood Grouping Reagent § 660.20 Blood Grouping Reagent. (a) Proper name and definition. The proper name of this product shall be Blood Grouping...

  19. 21 CFR 110.20 - Plant and grounds.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Plant and grounds. 110.20 Section 110.20 Food and... Facilities § 110.20 Plant and grounds. (a) Grounds. The grounds about a food plant under the control of the... litter and waste, and cutting weeds or grass within the immediate vicinity of the plant buildings or...

  20. 21 CFR 71.20 - Publication of regulation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Publication of regulation. 71.20 Section 71.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR... food, drug, or cosmetic or article intended for coloring the human body; the manner in which such color...

  1. 21 CFR 71.20 - Publication of regulation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Publication of regulation. 71.20 Section 71.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR... food, drug, or cosmetic or article intended for coloring the human body; the manner in which such color...

  2. 21 CFR 71.20 - Publication of regulation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Publication of regulation. 71.20 Section 71.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR... food, drug, or cosmetic or article intended for coloring the human body; the manner in which such color...

  3. 21 CFR 346.20 - Keratolytic active ingredients.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Keratolytic active ingredients. 346.20 Section 346...) DRUGS FOR HUMAN USE ANORECTAL DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 346.20 Keratolytic active ingredients. The active ingredient of the product consists of any of the following when...

  4. 21 CFR 346.20 - Keratolytic active ingredients.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Keratolytic active ingredients. 346.20 Section 346...) DRUGS FOR HUMAN USE ANORECTAL DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 346.20 Keratolytic active ingredients. The active ingredient of the product consists of any of the following when...

  5. 21 CFR 346.20 - Keratolytic active ingredients.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Keratolytic active ingredients. 346.20 Section 346...) DRUGS FOR HUMAN USE ANORECTAL DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 346.20 Keratolytic active ingredients. The active ingredient of the product consists of any of the following when...

  6. 21 CFR 346.20 - Keratolytic active ingredients.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Keratolytic active ingredients. 346.20 Section 346...) DRUGS FOR HUMAN USE ANORECTAL DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 346.20 Keratolytic active ingredients. The active ingredient of the product consists of any of the following when...

  7. 21 CFR 346.20 - Keratolytic active ingredients.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Keratolytic active ingredients. 346.20 Section 346...) DRUGS FOR HUMAN USE ANORECTAL DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 346.20 Keratolytic active ingredients. The active ingredient of the product consists of any of the following when...

  8. 21 CFR 20.113 - Voluntary product defect reports.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Voluntary product defect reports. 20.113 Section 20.113 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.113 Voluntary product defect...

  9. 21 CFR 20.104 - Summaries of oral discussions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Summaries of oral discussions. 20.104 Section 20.104 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.104 Summaries of oral discussions...

  10. 21 CFR 129.20 - Plant construction and design.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Plant construction and design. 129.20 Section 129.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... § 129.20 Plant construction and design. (a) The bottling room shall be separated from other plant...

  11. 21 CFR 129.20 - Plant construction and design.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Plant construction and design. 129.20 Section 129.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... § 129.20 Plant construction and design. (a) The bottling room shall be separated from other plant...

  12. 21 CFR 129.20 - Plant construction and design.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Plant construction and design. 129.20 Section 129.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... § 129.20 Plant construction and design. (a) The bottling room shall be separated from other plant...

  13. 21 CFR 129.20 - Plant construction and design.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Plant construction and design. 129.20 Section 129.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION PROCESSING AND BOTTLING OF BOTTLED DRINKING WATER Buildings and Facilities...

  14. 21 CFR 341.20 - Nasal decongestant active ingredients.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Nasal decongestant active ingredients. 341.20 Section 341.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE COLD, COUGH, ALLERGY, BRONCHODILATOR, AND ANTIASTHMATIC DRUG PRODUCTS FOR...

  15. 21 CFR 129.20 - Plant construction and design.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Plant construction and design. 129.20 Section 129.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION PROCESSING AND BOTTLING OF BOTTLED DRINKING WATER Buildings and Facilities...

  16. 21 CFR 341.20 - Nasal decongestant active ingredients.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Nasal decongestant active ingredients. 341.20... OVER-THE-COUNTER HUMAN USE Active Ingredients § 341.20 Nasal decongestant active ingredients. The active ingredient of the product consists of any of the following when used within the dosage limits and...

  17. 21 CFR 341.20 - Nasal decongestant active ingredients.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Nasal decongestant active ingredients. 341.20... OVER-THE-COUNTER HUMAN USE Active Ingredients § 341.20 Nasal decongestant active ingredients. The active ingredient of the product consists of any of the following when used within the dosage limits and...

  18. 21 CFR 341.20 - Nasal decongestant active ingredients.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Nasal decongestant active ingredients. 341.20... OVER-THE-COUNTER HUMAN USE Active Ingredients § 341.20 Nasal decongestant active ingredients. The active ingredient of the product consists of any of the following when used within the dosage limits and...

  19. 21 CFR 341.20 - Nasal decongestant active ingredients.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Nasal decongestant active ingredients. 341.20... OVER-THE-COUNTER HUMAN USE Active Ingredients § 341.20 Nasal decongestant active ingredients. The active ingredient of the product consists of any of the following when used within the dosage limits and...

  20. 21 CFR 20.107 - Food and Drug Administration manuals.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Food and Drug Administration manuals. 20.107 Section 20.107 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.107 Food and Drug...

  1. 21 CFR 20.107 - Food and Drug Administration manuals.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Food and Drug Administration manuals. 20.107 Section 20.107 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.107 Food and Drug...

  2. 21 CFR 20.107 - Food and Drug Administration manuals.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Food and Drug Administration manuals. 20.107 Section 20.107 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.107 Food and Drug...

  3. 21 CFR 20.107 - Food and Drug Administration manuals.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Food and Drug Administration manuals. 20.107 Section 20.107 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.107 Food and Drug...

  4. 21 CFR 20.116 - Drug and device listing information.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Drug and device listing information. 20.116 Section 20.116 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.116 Drug and device listing...

  5. 21 CFR 20.107 - Food and Drug Administration manuals.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Food and Drug Administration manuals. 20.107 Section 20.107 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.107 Food and Drug...

  6. 21 CFR 20.119 - Lists of names and addresses.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Lists of names and addresses. 20.119 Section 20.119 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.119 Lists of names and addresses...

  7. 20 CFR 614.21 - Findings of Federal military agency.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Findings of Federal military agency. 614.21 Section 614.21 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR....23 applies as to: (1) Whether the individual has performed active service in the Armed Forces or the...

  8. 21 CFR 20.33 - Form or format of response.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Form or format of response. 20.33 Section 20.33 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION General Policy § 20.33 Form or format of response. (a) The Food and Drug Administration shall make...

  9. Identifying and Quantifying Sources of Fall Chinook Salmon Spawning Gravel to the Snake River in Hells Canyon

    NASA Astrophysics Data System (ADS)

    Welcker, C. W.; Burke, M.

    2015-12-01

    The Snake River in Hells Canyon supports a growing population of spawning Fall Chinook Salmon (Oncorhynchus tshawytscha) immediately downstream of the Hells Canyon Complex (HCC) of hydroelectric dams for the last 60 years. The long-term survival of this salmon run depends on the input of spawning gravel (25-150 mm) from local tributaries balancing the losses of spawning gravel through attrition and export out of the reach between the HCC and the Salmon River confluence. We are working to quantify the gravel input of these local tributaries at different time-scales and put this into the context of historical supply and transport. Long-term total sediment production rates of these tributaries estimated through various methods have varied by over 2 orders of magnitude, but we have recently completed 10Be work to constrain these estimates. We are measuring the change in storage of Fall Chinook spawning-size gravel through repeat multibeam echosounder surveys of the riverbed. The limited amount of repeat data collected to date has shown complex patterns of change in the riverbed. One possible driver of this complexity is the episodic and spatially variable nature of sediment inputs from these tributaries. We are attempting to quantify the frequency of the debris flows or floods capable of transporting spawning gravel through digitizing historic imagery of the last 60 years to determine the recurrence interval. We are measuring the magnitude of these events by surveying tributary fans pre and post-event to measure the sediment volume and particle size produced by specific events. These floods and debris flows are driven by extreme rainfall or snowmelt events, so we have also reconstructed historical meteorological conditions to identify the triggering conditions for transport, and identify the areas where snowmelt or rainfall is the more likely trigger. We are currently testing whether the unique bedrock geology of Hells Canyon can be used as a tracer to identify the

  10. 21 CFR 1010.20 - Electronic products intended for export.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Electronic products intended for export. 1010.20... (CONTINUED) RADIOLOGICAL HEALTH PERFORMANCE STANDARDS FOR ELECTRONIC PRODUCTS: GENERAL Exportation of Electronic Products § 1010.20 Electronic products intended for export. The performance standards prescribed...

  11. 21 CFR 1010.20 - Electronic products intended for export.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Electronic products intended for export. 1010.20... (CONTINUED) RADIOLOGICAL HEALTH PERFORMANCE STANDARDS FOR ELECTRONIC PRODUCTS: GENERAL Exportation of Electronic Products § 1010.20 Electronic products intended for export. The performance standards prescribed...

  12. 21 CFR 1010.20 - Electronic products intended for export.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Electronic products intended for export. 1010.20... (CONTINUED) RADIOLOGICAL HEALTH PERFORMANCE STANDARDS FOR ELECTRONIC PRODUCTS: GENERAL Exportation of Electronic Products § 1010.20 Electronic products intended for export. The performance standards prescribed...

  13. Divergent Effects of Beliefs in Heaven and Hell on National Crime Rates

    PubMed Central

    Shariff, Azim F.; Rhemtulla, Mijke

    2012-01-01

    Though religion has been shown to have generally positive effects on normative ‘prosocial’ behavior, recent laboratory research suggests that these effects may be driven primarily by supernatural punishment. Supernatural benevolence, on the other hand, may actually be associated with less prosocial behavior. Here, we investigate these effects at the societal level, showing that the proportion of people who believe in hell negatively predicts national crime rates whereas belief in heaven predicts higher crime rates. These effects remain after accounting for a host of covariates, and ultimately prove stronger predictors of national crime rates than economic variables such as GDP and income inequality. Expanding on laboratory research on religious prosociality, this is the first study to tie religious beliefs to large-scale cross-national trends in pro- and anti-social behavior. PMID:22723927

  14. 21 CFR 601.20 - Biologics licenses; issuance and conditions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Biologics licenses; issuance and conditions. 601.20 Section 601.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... examination of the product and upon a determination that the product complies with the standards established...

  15. 21 CFR 601.20 - Biologics licenses; issuance and conditions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Biologics licenses; issuance and conditions. 601.20 Section 601.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... only upon examination of the product and upon a determination that the product complies with the...

  16. Interview: Professor Helle Neergaard, President of the European Council for Small Business and Entrepreneurship, on the Nature of Creativity, Innovation and Entrepreneurship

    ERIC Educational Resources Information Center

    Industry and Higher Education, 2015

    2015-01-01

    On August 13, 2014, Rita G. Klapper conducted a Skype interview with Helle Neergaard. Neergaard is not only President of the European Council for Small Business and Entrepreneurship, but also Docent at the Hanken School of Economics, and Professor at iCARE, Department of Business Administration, School of Business and Social Sciences, University…

  17. 21 CFR 20.109 - Data and information obtained by contract.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Data and information obtained by contract. 20.109 Section 20.109 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.109 Data and information...

  18. 21 CFR 20.115 - Product codes for manufacturing or sales dates.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Product codes for manufacturing or sales dates. 20.115 Section 20.115 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.115 Product codes...

  19. Hell Is Other People? Gender and Interactions with Strangers in the Workplace Influence a Person’s Risk of Depression

    PubMed Central

    Fischer, Sebastian; Wiemer, Anita; Diedrich, Laura; Moock, Jörn; Rössler, Wulf

    2014-01-01

    We suggest that interactions with strangers at work influence the likelihood of depressive disorders, as they serve as an environmental stressor, which are a necessary condition for the onset of depression according to diathesis-stress models of depression. We examined a large dataset (N = 76,563 in K = 196 occupations) from the German pension insurance program and the Occupational Information Network dataset on occupational characteristics. We used a multilevel framework with individuals and occupations as levels of analysis. We found that occupational environments influence employees’ risks of depression. In line with the quotation that ‘hell is other people’ frequent conflictual contacts were related to greater likelihoods of depression in both males and females (OR = 1.14, p<.05). However, interactions with the public were related to greater likelihoods of depression for males but lower likelihoods of depression for females (ORintercation = 1.21, p<.01). We theorize that some occupations may involve interpersonal experiences with negative emotional tones that make functional coping difficult and increase the risk of depression. In other occupations, these experiences have neutral tones and allow for functional coping strategies. Functional strategies are more often found in women than in men. PMID:25075855

  20. 21 CFR 20.109 - Data and information obtained by contract.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Data and information obtained by contract. 20.109... GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.109 Data and information obtained by contract. (a) All data and information obtained by the Food and Drug Administration by contract...

  1. 21 CFR 20.62 - Inter- or intra-agency memoranda or letters.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Inter- or intra-agency memoranda or letters. 20.62 Section 20.62 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Exemptions § 20.62 Inter- or intra-agency memoranda or letters. All communications...

  2. 21 CFR 20.100 - Applicability; cross-reference to other regulations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... chapter. (8) Action levels for natural and unavoidable defects in food for human use, in § 110.110(e) of... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Applicability; cross-reference to other regulations. 20.100 Section 20.100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN...

  3. 21 CFR 20.100 - Applicability; cross-reference to other regulations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... chapter. (8) Action levels for natural and unavoidable defects in food for human use, in § 110.110(e) of... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Applicability; cross-reference to other regulations. 20.100 Section 20.100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN...

  4. 21 CFR 20.100 - Applicability; cross-reference to other regulations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... chapter. (8) Action levels for natural and unavoidable defects in food for human use, in § 110.110(e) of... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Applicability; cross-reference to other regulations. 20.100 Section 20.100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN...

  5. Stories of Hell and Healing: Internet Users' Construction of Benzodiazepine Distress and Withdrawal.

    PubMed

    Fixsen, Alison M; Ridge, Damien

    2017-11-01

    Benzodiazepines are a group of drugs used mainly as sedatives, hypnotics, antiepileptics, and muscle relaxants. Consumption is recommended for 2 to 4 weeks only, due to fast onset of dependency and potentially distressing withdrawal symptoms. Few peer-review studies have drawn on the user experiences and language to appreciate firsthand experiences of benzodiazepine withdrawal or discontinuation syndrome. We looked extensively at patient stories of benzodiazepine withdrawal and recovery on Internet support sites and YouTube. Our analysis indicated that users employ rich metaphors to portray the psychologically disturbing and protracted nature of their suffering. We identified seven major themes: hell and isolation, anxiety and depression, alienation, physical distress, anger and remorse, waves and windows, and healing and renewal. By posting success stories, ex-users make known that "healing" can be a long, unpredictable process, but distress does lessen, and recovery can happen.

  6. 20 CFR 435.21 - Standards for financial management systems.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ORGANIZATIONS, AND COMMERCIAL ORGANIZATIONS Post-Award Requirements Financial and Program Management § 435.21 Standards for financial management systems. (a) Introduction. SSA requires recipients to relate financial... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Standards for financial management systems...

  7. 21 CFR 1002.20 - Reporting of accidental radiation occurrences.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Reporting of accidental radiation occurrences... SERVICES (CONTINUED) RADIOLOGICAL HEALTH RECORDS AND REPORTS Manufacturers' Reports on Accidental Radiation Occurrences § 1002.20 Reporting of accidental radiation occurrences. (a) Manufacturers of electronic products...

  8. 21 CFR 1002.20 - Reporting of accidental radiation occurrences.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Reporting of accidental radiation occurrences... SERVICES (CONTINUED) RADIOLOGICAL HEALTH RECORDS AND REPORTS Manufacturers' Reports on Accidental Radiation Occurrences § 1002.20 Reporting of accidental radiation occurrences. (a) Manufacturers of electronic products...

  9. 21 CFR 1002.20 - Reporting of accidental radiation occurrences.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Reporting of accidental radiation occurrences... SERVICES (CONTINUED) RADIOLOGICAL HEALTH RECORDS AND REPORTS Manufacturers' Reports on Accidental Radiation Occurrences § 1002.20 Reporting of accidental radiation occurrences. (a) Manufacturers of electronic products...

  10. 21 CFR 25.20 - Actions requiring preparation of an environmental assessment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Actions requiring preparation of an environmental assessment. 25.20 Section 25.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ENVIRONMENTAL IMPACT CONSIDERATIONS Agency Actions Requiring Environmental Consideration...

  11. 21 CFR 20.89 - Communications with foreign government officials.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.89 Communications with foreign... communications with any member of the public, except that: (a) Investigatory records compiled for law enforcement... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Communications with foreign government officials...

  12. 21 CFR 352.20 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Permitted combinations of active ingredients. 352... INDEFINITELY] Active Ingredients § 352.20 Permitted combinations of active ingredients. The SPF of any...) Combinations of sunscreen active ingredients. (1) Two or more sunscreen active ingredients identified in § 352...

  13. 21 CFR 352.20 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Permitted combinations of active ingredients. 352... INDEFINITELY] Active Ingredients § 352.20 Permitted combinations of active ingredients. The SPF of any...) Combinations of sunscreen active ingredients. (1) Two or more sunscreen active ingredients identified in § 352...

  14. 21 CFR 352.20 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Permitted combinations of active ingredients. 352... INDEFINITELY] Active Ingredients § 352.20 Permitted combinations of active ingredients. The SPF of any...) Combinations of sunscreen active ingredients. (1) Two or more sunscreen active ingredients identified in § 352...

  15. 21 CFR 352.20 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Permitted combinations of active ingredients. 352... INDEFINITELY] Active Ingredients § 352.20 Permitted combinations of active ingredients. The SPF of any...) Combinations of sunscreen active ingredients. (1) Two or more sunscreen active ingredients identified in § 352...

  16. 21 CFR 352.20 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Permitted combinations of active ingredients. 352... INDEFINITELY] Active Ingredients § 352.20 Permitted combinations of active ingredients. The SPF of any...) Combinations of sunscreen active ingredients. (1) Two or more sunscreen active ingredients identified in § 352...

  17. 21 CFR 1403.20 - Standards for financial management systems.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 9 2011-04-01 2011-04-01 false Standards for financial management systems. 1403... Financial Administration § 1403.20 Standards for financial management systems. (a) A State must expend and... of applicable statutes. (b) The financial management systems of other grantees and subgrantees must...

  18. 21 CFR 1403.20 - Standards for financial management systems.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 9 2013-04-01 2013-04-01 false Standards for financial management systems. 1403... Financial Administration § 1403.20 Standards for financial management systems. (a) A State must expend and... of applicable statutes. (b) The financial management systems of other grantees and subgrantees must...

  19. 21 CFR 1403.20 - Standards for financial management systems.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 9 2012-04-01 2012-04-01 false Standards for financial management systems. 1403... Financial Administration § 1403.20 Standards for financial management systems. (a) A State must expend and... of applicable statutes. (b) The financial management systems of other grantees and subgrantees must...

  20. 21 CFR 1403.20 - Standards for financial management systems.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 9 2014-04-01 2014-04-01 false Standards for financial management systems. 1403... Financial Administration § 1403.20 Standards for financial management systems. (a) A State must expend and... of applicable statutes. (b) The financial management systems of other grantees and subgrantees must...

  1. 21 CFR 20.1 - Testimony by Food and Drug Administration employees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Testimony by Food and Drug Administration employees. 20.1 Section 20.1 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... laws administered by the Food and Drug Administration, shall give any testimony before any tribunal...

  2. 21 CFR 1403.20 - Standards for financial management systems.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Standards for financial management systems. 1403... Financial Administration § 1403.20 Standards for financial management systems. (a) A State must expend and account for grant funds in accordance with State laws and procedures for expending and accounting for its...

  3. 21 CFR 20.115 - Product codes for manufacturing or sales dates.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Product codes for manufacturing or sales dates. 20.115 Section 20.115 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... the label or in labeling or otherwise used in connection with a product subject to the jurisdiction of...

  4. 21 CFR 347.20 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Permitted combinations of active ingredients. 347... Active Ingredients § 347.20 Permitted combinations of active ingredients. (a) Combinations of skin protectant active ingredients. (1) Any two or more of the ingredients identified in § 347.10(a), (d), (e), (i...

  5. 21 CFR 347.20 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Permitted combinations of active ingredients. 347... Active Ingredients § 347.20 Permitted combinations of active ingredients. (a) Combinations of skin protectant active ingredients. (1) Any two or more of the ingredients identified in § 347.10(a), (d), (e), (i...

  6. 21 CFR 347.20 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Permitted combinations of active ingredients. 347... Active Ingredients § 347.20 Permitted combinations of active ingredients. (a) Combinations of skin protectant active ingredients. (1) Any two or more of the ingredients identified in § 347.10(a), (d), (e), (i...

  7. 21 CFR 347.20 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Permitted combinations of active ingredients. 347... Active Ingredients § 347.20 Permitted combinations of active ingredients. (a) Combinations of skin protectant active ingredients. (1) Any two or more of the ingredients identified in § 347.10(a), (d), (e), (i...

  8. 21 CFR 14.20 - Notice of hearing before an advisory committee.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Notice of hearing before an advisory committee. 14.20 Section 14.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... function of the committee; (4) A list of all agenda items, showing whether each will be discussed in an...

  9. 21 CFR 14.20 - Notice of hearing before an advisory committee.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Notice of hearing before an advisory committee. 14.20 Section 14.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... function of the committee; (4) A list of all agenda items, showing whether each will be discussed in an...

  10. 21 CFR 14.20 - Notice of hearing before an advisory committee.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Notice of hearing before an advisory committee. 14.20 Section 14.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... function of the committee; (4) A list of all agenda items, showing whether each will be discussed in an...

  11. 21 CFR 14.20 - Notice of hearing before an advisory committee.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Notice of hearing before an advisory committee. 14.20 Section 14.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... function of the committee; (4) A list of all agenda items, showing whether each will be discussed in an...

  12. 21 CFR 14.20 - Notice of hearing before an advisory committee.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Notice of hearing before an advisory committee. 14.20 Section 14.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... function of the committee; (4) A list of all agenda items, showing whether each will be discussed in an...

  13. Highlights from the CERN/ESO/NordForsk ''Gender in Physics Day''

    NASA Astrophysics Data System (ADS)

    Primas, F.; Guinot, G.; Strandberg, L.

    2017-03-01

    In their role as observers on the EU Gender Equality Network in the European Research Area (GENERA) project, funded under the Horizon 2020 framework, CERN, ESO and NordForsk joined forces and organised a Gender in Physics Day at the CERN Globe of Science and Innovation. The one-day conference aimed to examine innovative activities promoting gender equality, and to discuss gender-oriented policies and best practice in the European Research Area (with special emphasis on intergovernmental organisations), as well as the importance of building solid networks. The event was very well attended and was declared a success. The main highlights of the meeting are reported.

  14. Pregna-5,17(20)-dien-21-oyl amides affecting sterol and triglyceride biosynthesis in Hep G2 cells.

    PubMed

    Stulov, Sergey V; Mankevich, Olga V; Dugin, Nikita O; Novikov, Roman A; Timofeev, Vladimir P; Misharin, Alexander Yu

    2013-04-01

    Synthesis of series [17(20)Z]- and [17(20)E]-pregna-5,17(20)-dien-21-oyl amides, containing polar substituents in amide moiety, based on rearrangement of 17α-bromo-21-iodo-3β-acetoxypregn-5-en-20-one caused by amines, is presented. The titled compounds were evaluated for their potency to regulate sterol and triglyceride biosynthesis in human hepatoma Hep G2 cells in comparison with 25-hydroxycholesterol. Three [17(20)E]-pregna-5,17(20)-dien-21-oyl amides at a concentrations of 5 μM inhibited sterol biosynthesis and stimulated triglyceride biosynthesis; their regulatory potency was dependent on the structure of amide moiety; the isomeric [17(20)Z]-pregna-5,17(20)-dien-21-oyl amides were inactive. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. 21 CFR 20.112 - Voluntary drug experience reports submitted by physicians and hospitals.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Voluntary drug experience reports submitted by physicians and hospitals. 20.112 Section 20.112 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20...

  16. 21 CFR 20.110 - Data and information about Food and Drug Administration employees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Data and information about Food and Drug Administration employees. 20.110 Section 20.110 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.110...

  17. 21 CFR 20.86 - Disclosure in administrative or court proceedings.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.86 Disclosure in administrative or court proceedings. Data and information otherwise exempt from public disclosure may be revealed in Food and Drug... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Disclosure in administrative or court proceedings...

  18. 21 CFR 20.86 - Disclosure in administrative or court proceedings.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.86 Disclosure in administrative or court proceedings. Data and information otherwise exempt from public disclosure may be revealed in Food and Drug... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Disclosure in administrative or court proceedings...

  19. 21 CFR 20.86 - Disclosure in administrative or court proceedings.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.86 Disclosure in administrative or court proceedings. Data and information otherwise exempt from public disclosure may be revealed in Food and Drug... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Disclosure in administrative or court proceedings...

  20. 21 CFR 20.86 - Disclosure in administrative or court proceedings.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.86 Disclosure in administrative or court proceedings. Data and information otherwise exempt from public disclosure may be revealed in Food and Drug... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Disclosure in administrative or court proceedings...

  1. 21 CFR 20.86 - Disclosure in administrative or court proceedings.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.86 Disclosure in administrative or court proceedings. Data and information otherwise exempt from public disclosure may be revealed in Food and Drug... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Disclosure in administrative or court proceedings...

  2. 21 CFR 1311.20 - Coordinators for CSOS digital certificate holders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Coordinators for CSOS digital certificate holders... REQUIREMENTS FOR ELECTRONIC ORDERS AND PRESCRIPTIONS (Eff. 6-1-10) Obtaining and Using Digital Certificates for Electronic Orders § 1311.20 Coordinators for CSOS digital certificate holders. (a) Each registrant...

  3. 21 CFR 70.20 - Packaging requirements for straight colors (other than hair dyes).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Packaging requirements for straight colors (other than hair dyes). 70.20 Section 70.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL COLOR ADDITIVES Packaging and Labeling § 70.20 Packaging requirements for straight colors (other than hair dyes)....

  4. Reworking of Cretaceous dinosaurs into Paleocene channel deposits, upper Hell Creek Formation, Montana

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lofgren, D.L.; Hotton, C.L.; Runkel, A.C.

    1990-09-01

    Dinosaur teeth from Paleocene channel fills have been interpreted as indicating dinosaur survival into the Paleocene. However, enormous potential for reworking exists because these records are restricted to large channel fills that are deeply incised into Cretaceous strata. Identification of reworked fossils is usually equivocal. This problem is illustrated by the Black Spring Coulee channel fill, a dinosaur-bearing Paleocene deposit in the upper Hell Creek Formation of eastern Montana. In this example, the reworked nature of well-preserved dinosaur bones is apparent only after detailed sedimentological and palynological analysis. Because of the potential for reworking, dinosaur remains derived from Paleocene fluvialmore » deposits should not be assigned a Paleocene age unless the (1) are found in floodplain deposits, (2) are articulated, (3) are in channels that do not incise Cretaceous strata, or (4) are demonstrably reworked from Paleocene deposits. To date, reports of Paleocene dinosaurs do not fulfill any of these criteria. Thus, the proposal that dinosaurs persisted into the Paleocene remains unsubstantiated.« less

  5. Listen; There's a Hell of a Good Universe Next Door; Let's Go

    NASA Technical Reports Server (NTRS)

    Rigby, Jane R.

    2012-01-01

    Scientific research is key to our nation's technological and economic development. One can attempt to focus research toward specific applications, but science has a way of surprising us. Think for example of the "charge-couple device", which was originally invented for memory storage, but became the modern digital camera that is used everywhere from camera phones to the Hubble Space Telescope. Using digital cameras, Hubble has taken pictures that reach back 12 billion light-years into the past, when the Universe was only 1-2 billion years old. Such results would never have been possible with the film cameras Hubble was originally supposed to use. Over the past two decades, Hubble and other telescopes have shown us much about the Universe -- many of these results are shocking. Our galaxy is swarming with planets; most of the mass in the Universe is invisible; and our Universe is accelerating ever faster and faster for unknown reasons. Thus, we live in a "hell of a good universe", to quote e.e. cummings, that we fundamentally don't understand. This means that you, as young scientists, have many worlds to discover

  6. Polymorphisme de l'apolipoprotéine E dans la population du nord du Maroc: fréquence et influence sur les paramètres lipidiques

    PubMed Central

    Benyahya, Fatiha; Barakat, Amina; Ghailani, Naima; Bennani, Mohcine

    2013-01-01

    Introduction L'objectif de ce travail est de déterminer les fréquences alléliques et génotypiques des sites polymorphes situés dans le gène de l'apolipoprotéine E (apo E) ainsi que leur impact sur les paramètres cliniques et lipidiques dans un échantillon de la population du nord du Maroc cliniquement diagnostiqué ADH. Méthodes Le génotype de l'apo E a été analysé par séquençage direct chez 46 patients cliniquement diagnostiqués ADH selon les critères standards. Résultats Les fréquences des allèles epsilon 3, epsilon 2 et epsilon 4 ont été respectivement 78.3%, 2.2% et 19.6%. La fréquence de l'allèle epsilon 4 est très élevée chez la population du nord du Maroc en comparaison avec les populations des autres régions marocaines. Elle est similaire à celle rapportée dans les pays de l'Europe du nord. Les taux du cholestérol total, du cholestérol LDL ainsi que la présence des xanthomes et les maladies cardiovasculaires ne différent pas entre les génotypes de l'apoE. En revanche, les résultats ont montré une influence de l'allèle epsilon4 sur le taux des triglycérides chez les sujets obèses. Conclusion Le génotype de l'apoE ne peut expliquer le phénotype clinique et biochimique présenté par des patients du Nord du Maroc cliniquement diagnostiqués ADH. PMID:24396563

  7. Research Priorities for FCTC Articles 20, 21, and 22: Surveillance/Evaluation and Information Exchange

    PubMed Central

    2013-01-01

    Introduction: Framework Convention on Tobacco Control (FCTC) Articles 20, 21, and 22 call for strong monitoring and reporting of tobacco use and factors influencing use and disease (Articles 20 and 21) and for collaboration among the Parties and relevant organizations to share resources, knowledge, and expertise on all relevant tobacco control strategies (Article 22). Methods: This paper provides background information and discusses research strategies that would strengthen these efforts and better inform the Parties. By necessity, Articles 20 and 21 are discussed separately from Article 22, although 1 example that relates to both 20/21 and 22 is discussed at the end. Results: Twelve important research opportunities on surveillance and evaluation are recognized, along with 4 on collaboration. The authors believe that the 6 most important areas for research would study (a) possible underreporting of tobacco use among certain demographic groups in some countries, (b) measures of industry activities, (c) optimal sampling strategies, (d) sentinel surveillance, (e) networks of tobacco companies and their partners as they promote tobacco use and interfere with implementation of the FCTC, and (f) network/relationship factors that impact diffusion of knowledge and decision making on the implementation of the FCTC. In addition, we call for a review process of existing surveillance and evaluation strategies to coordinate activities to make optimal use of existing resources. This activity would involve networking as prescribed in Article 22. Conclusions: Studies and activities such as these would facilitate control of the tobacco epidemic. PMID:23335488

  8. Research priorities for FCTC Articles 20, 21, and 22: surveillance/evaluation and information exchange.

    PubMed

    Giovino, Gary A; Kulak, Jessica A; Kalsbeek, William D; Leischow, Scott J

    2013-04-01

    Framework Convention on Tobacco Control (FCTC) Articles 20, 21, and 22 call for strong monitoring and reporting of tobacco use and factors influencing use and disease (Articles 20 and 21) and for collaboration among the Parties and relevant organizations to share resources, knowledge, and expertise on all relevant tobacco control strategies (Article 22). This paper provides background information and discusses research strategies that would strengthen these efforts and better inform the parties. By necessity, Articles 20 and 21 are discussed separately from Article 22, although 1 example that relates to both 20/21 and 22 is discussed at the end. Twelve important research opportunities on surveillance and evaluation are recognized, along with 4 on collaboration. The authors believe that the 6 most important areas for research would study (a) possible underreporting of tobacco use among certain demographic groups in some countries, (b) measures of industry activities, (c) optimal sampling strategies, (d) sentinel surveillance, (e) networks of tobacco companies and their partners as they promote tobacco use and interfere with implementation of the FCTC, and (f) network/relationship factors that impact diffusion of knowledge and decision making on the implementation of the FCTC. In addition, we call for a review process of existing surveillance and evaluation strategies to coordinate activities to make optimal use of existing resources. This activity would involve networking as prescribed in Article 22. Studies and activities such as these would facilitate control of the tobacco epidemic.

  9. 21 CFR 212.20 - What activities must I perform to ensure drug quality?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false What activities must I perform to ensure drug quality? 212.20 Section 212.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR POSITRON EMISSION TOMOGRAPHY...

  10. 21 CFR 212.20 - What activities must I perform to ensure drug quality?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 4 2011-04-01 2011-04-01 false What activities must I perform to ensure drug quality? 212.20 Section 212.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR POSITRON EMISSION TOMOGRAPHY...

  11. 21 CFR 70.20 - Packaging requirements for straight colors (other than hair dyes).

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Packaging requirements for straight colors (other than hair dyes). 70.20 Section 70.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH... straight colors (other than hair dyes). Straight colors shall be packaged in containers which prevent...

  12. 21 CFR 70.20 - Packaging requirements for straight colors (other than hair dyes).

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Packaging requirements for straight colors (other than hair dyes). 70.20 Section 70.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH... straight colors (other than hair dyes). Straight colors shall be packaged in containers which prevent...

  13. 21 CFR 70.20 - Packaging requirements for straight colors (other than hair dyes).

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Packaging requirements for straight colors (other than hair dyes). 70.20 Section 70.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH... straight colors (other than hair dyes). Straight colors shall be packaged in containers which prevent...

  14. 21 CFR 70.20 - Packaging requirements for straight colors (other than hair dyes).

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Packaging requirements for straight colors (other than hair dyes). 70.20 Section 70.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH... straight colors (other than hair dyes). Straight colors shall be packaged in containers which prevent...

  15. 21 CFR 570.20 - General principles for evaluating the safety of food additives.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 6 2011-04-01 2011-04-01 false General principles for evaluating the safety of food additives. 570.20 Section 570.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES Food Additive...

  16. Configurational Reassignment and Improved Preparation of the Competitive IL-6 Receptor Antagonist 20R,21R-Epoxyresibufogenin-3-formate

    PubMed Central

    Boos, Terrence L.; Cheng, Kejun; Greiner, Elisabeth; Deschamps, Jeffrey R.; Jacobson, Arthur E.; Rice, Kenner C.

    2012-01-01

    20R,21R-Epoxyresibufogenin-3-formate (1) and 20S,21S-epoxyresibufogenin-3-formate (2) were synthesized from commercial resibufogenin (3) using known procedures. The major product (1) was dextrorotatory, as was the major product from the reported synthesis of epoxyresibufogenin-3-formate; however, the literature (+)-compound was assigned the 20S,21S-configuration based on NMR data. We have now unequivocally determined, using single-crystal X-ray structure analyses of the major and minor products of the synthesis and of their derivatives, that the major product from the synthesis was (+)-20R,21R-epoxyresibufogenin-3-formate (1). Our minor synthetic product was determined to have the (-)-20S,21S-configuration (2). The (+)-20R,21R-compound 1 has been found to have high affinity for the IL-6 receptor and to act as an IL-6 antagonist. A greatly improved synthesis of 1 was achieved through oxidation of preformed resibufogenin-3-formate. This has enabled us to prepare, from the very expensive commercial resibufogenin, considerably larger quantities of 1, the only known non-peptide small molecule IL-6 antagonist. PMID:22360661

  17. 21 CFR 515.20 - Approval of medicated feed mill license applications.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Approval of medicated feed mill license... SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS MEDICATED FEED MILL LICENSE Administrative Actions on Licenses § 515.20 Approval of medicated feed mill license applications. Within 90 days after an...

  18. 21 CFR 331.20 - Determination of percent contribution of active ingredients.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 5 2011-04-01 2011-04-01 false Determination of percent contribution of active... Procedures § 331.20 Determination of percent contribution of active ingredients. To determine the percent contribution of an antacid active ingredient, place an accurately weighed amount of the antacid active...

  19. 21 CFR 331.20 - Determination of percent contribution of active ingredients.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Determination of percent contribution of active... Procedures § 331.20 Determination of percent contribution of active ingredients. To determine the percent contribution of an antacid active ingredient, place an accurately weighed amount of the antacid active...

  20. 21 CFR 331.20 - Determination of percent contribution of active ingredients.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Determination of percent contribution of active... Procedures § 331.20 Determination of percent contribution of active ingredients. To determine the percent contribution of an antacid active ingredient, place an accurately weighed amount of the antacid active...

  1. 21 CFR 331.20 - Determination of percent contribution of active ingredients.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Determination of percent contribution of active... Procedures § 331.20 Determination of percent contribution of active ingredients. To determine the percent contribution of an antacid active ingredient, place an accurately weighed amount of the antacid active...

  2. Proceedings Report from the Sustainability Education Summit, September 20-21, 2010

    ERIC Educational Resources Information Center

    US Department of Education, 2011

    2011-01-01

    The first-ever U. S. Department of Education summit on sustainability, "Sustainability Education Summit: Citizenship and Pathways for a Green Economy," was held on Sept. 20-21, 2010, in Washington, D.C. The Sustainability Education Summit (the Summit) brought together leaders from higher education, business and industry, labor,…

  3. 21 CFR 20.88 - Communications with State and local government officials.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.88 Communications with State and local... status as communications with any member of the public, except that: (1) Investigatory records compiled... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Communications with State and local government...

  4. 21 CFR 60.20 - FDA action on regulatory review period determinations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false FDA action on regulatory review period... SERVICES GENERAL PATENT TERM RESTORATION Regulatory Review Period Determinations § 60.20 FDA action on regulatory review period determinations. (a) FDA will consult its records and experts to verify the dates...

  5. 21 CFR 60.20 - FDA action on regulatory review period determinations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false FDA action on regulatory review period... SERVICES GENERAL PATENT TERM RESTORATION Regulatory Review Period Determinations § 60.20 FDA action on regulatory review period determinations. (a) FDA will consult its records and experts to verify the dates...

  6. 21 CFR 60.20 - FDA action on regulatory review period determinations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false FDA action on regulatory review period... SERVICES GENERAL PATENT TERM RESTORATION Regulatory Review Period Determinations § 60.20 FDA action on regulatory review period determinations. (a) FDA will consult its records and experts to verify the dates...

  7. 21 CFR 60.20 - FDA action on regulatory review period determinations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false FDA action on regulatory review period... SERVICES GENERAL PATENT TERM RESTORATION Regulatory Review Period Determinations § 60.20 FDA action on regulatory review period determinations. (a) FDA will consult its records and experts to verify the dates...

  8. 21 CFR 60.20 - FDA action on regulatory review period determinations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false FDA action on regulatory review period... SERVICES GENERAL PATENT TERM RESTORATION Regulatory Review Period Determinations § 60.20 FDA action on regulatory review period determinations. (a) FDA will consult its records and experts to verify the dates...

  9. 21 CFR 20.120 - Records available in Food and Drug Administration Public Reading Rooms.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Records available in Food and Drug Administration Public Reading Rooms. 20.120 Section 20.120 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.120 Records available in Food and Drug...

  10. 21 CFR 20.120 - Records available in Food and Drug Administration Public Reading Rooms.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Records available in Food and Drug Administration Public Reading Rooms. 20.120 Section 20.120 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.120 Records available in Food and Drug...

  11. 21 CFR 20.120 - Records available in Food and Drug Administration Public Reading Rooms.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Records available in Food and Drug Administration Public Reading Rooms. 20.120 Section 20.120 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of Records § 20.120 Records available in Food and Drug...

  12. 21 CFR 20.2 - Production of records by Food and Drug Administration employees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... upon an officer or employee of the Food and Drug Administration commanding the production of any record... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Production of records by Food and Drug Administration employees. 20.2 Section 20.2 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND...

  13. 20 CFR 222.21 - When marriage is terminated by final divorce.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 1 2012-04-01 2012-04-01 false When marriage is terminated by final divorce... Widow(er) § 222.21 When marriage is terminated by final divorce. A final divorce, often referred to as an absolute divorce, completely dissolves the marriage relationship and restores the parties to the...

  14. 20 CFR 222.21 - When marriage is terminated by final divorce.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When marriage is terminated by final divorce... Widow(er) § 222.21 When marriage is terminated by final divorce. A final divorce, often referred to as an absolute divorce, completely dissolves the marriage relationship and restores the parties to the...

  15. 20 CFR 222.21 - When marriage is terminated by final divorce.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 1 2013-04-01 2012-04-01 true When marriage is terminated by final divorce... Widow(er) § 222.21 When marriage is terminated by final divorce. A final divorce, often referred to as an absolute divorce, completely dissolves the marriage relationship and restores the parties to the...

  16. 20 CFR 222.21 - When marriage is terminated by final divorce.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 1 2011-04-01 2011-04-01 false When marriage is terminated by final divorce... Widow(er) § 222.21 When marriage is terminated by final divorce. A final divorce, often referred to as an absolute divorce, completely dissolves the marriage relationship and restores the parties to the...

  17. 20 CFR 222.21 - When marriage is terminated by final divorce.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 1 2014-04-01 2012-04-01 true When marriage is terminated by final divorce... Widow(er) § 222.21 When marriage is terminated by final divorce. A final divorce, often referred to as an absolute divorce, completely dissolves the marriage relationship and restores the parties to the...

  18. 21 CFR 20.114 - Data and information submitted pursuant to cooperative quality assurance agreements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Data and information submitted pursuant to cooperative quality assurance agreements. 20.114 Section 20.114 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Availability of Specific Categories of...

  19. 21 CFR 111.20 - What design and construction requirements apply to your physical plant?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What design and construction requirements apply to your physical plant? 111.20 Section 111.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION CURRENT GOOD MANUFACTURING PRACTICE IN...

  20. Anthropogenic Impacts of Recreational Use on Sandbars in Hells Canyon on the Snake River, Idaho

    NASA Astrophysics Data System (ADS)

    Morehead, M. D.

    2014-12-01

    Sandbars along large rivers are important cultural, recreational, and natural resources. In modern, historic and prehistoric times the sandbars have been used for camping, hunting, fishing and recreational activities. Sandbars are a dynamic geomorphic unit of the river system that stores and exchanges sand with the main river channel. Both natural and anthropogenic changes to river systems affect the size, shape and dynamics of sandbars. During high spring flows, the Snake River can resupply and build the sand bars. During the lower flows of the summer and fall the sand is redistributed to lower levels by natural and anthropogenic forces, where it can be remobilized by the river and exported from the bar. During the summer and fall high use season many people camp and recreate on the bars and redistribute the sand. This study utilizes change detection from repeat high resolution terrestrial LiDAR scanning surveys to study the impacts humans have on the sandbars in Hells Canyon. Nearly a decade of annual LiDAR and Bathymetric surveys were used to place these recreational impacts into the context of overall sandbar dynamics.

  1. 21 CFR 20.30 - Food and Drug Administration Freedom of Information Staff.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Food and Drug Administration Freedom of... HUMAN SERVICES GENERAL PUBLIC INFORMATION General Policy § 20.30 Food and Drug Administration Freedom of Information Staff. (a) The Office responsible for agency compliance with the Freedom of Information Act and...

  2. 21 CFR 20.81 - Data and information previously disclosed to the public.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Data and information previously disclosed to the... SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.81 Data and information previously... disclosure pursuant to subpart D of this part is available for public disclosure to the extent that it...

  3. 21 CFR 20.81 - Data and information previously disclosed to the public.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Data and information previously disclosed to the... SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.81 Data and information previously... disclosure pursuant to subpart D of this part is available for public disclosure to the extent that it...

  4. 21 CFR 20.81 - Data and information previously disclosed to the public.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Data and information previously disclosed to the... SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.81 Data and information previously... disclosure pursuant to subpart D of this part is available for public disclosure to the extent that it...

  5. 21 CFR 20.108 - Agreements between the Food and Drug Administration and other departments, agencies, and...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Specific Categories of Records § 20.108 Agreements between the Food and Drug Administration and other... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Agreements between the Food and Drug Administration and other departments, agencies, and organizations. 20.108 Section 20.108 Food and Drugs FOOD AND...

  6. 21 CFR 20.63 - Personnel, medical, and similar files, disclosure of which constitutes a clearly unwarranted...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Personnel, medical, and similar files, disclosure of which constitutes a clearly unwarranted invasion of personal privacy. 20.63 Section 20.63 Food and... Exemptions § 20.63 Personnel, medical, and similar files, disclosure of which constitutes a clearly...

  7. 21 CFR 20.63 - Personnel, medical, and similar files, disclosure of which constitutes a clearly unwarranted...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Personnel, medical, and similar files, disclosure of which constitutes a clearly unwarranted invasion of personal privacy. 20.63 Section 20.63 Food and... Exemptions § 20.63 Personnel, medical, and similar files, disclosure of which constitutes a clearly...

  8. 21 CFR 207.20 - Who must register and submit a drug list.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., preparation, propagation, compounding, or processing of an animal feed bearing or containing an animal drug (i... drug application, a new animal drug application, an abbreviated new animal drug application, a... 21 Food and Drugs 4 2012-04-01 2012-04-01 false Who must register and submit a drug list. 207.20...

  9. 21 CFR 207.20 - Who must register and submit a drug list.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., preparation, propagation, compounding, or processing of an animal feed bearing or containing an animal drug (i... drug application, a new animal drug application, an abbreviated new animal drug application, a... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Who must register and submit a drug list. 207.20...

  10. 21 CFR 207.20 - Who must register and submit a drug list.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., preparation, propagation, compounding, or processing of an animal feed bearing or containing an animal drug (i... drug application, a new animal drug application, an abbreviated new animal drug application, a... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Who must register and submit a drug list. 207.20...

  11. 21 CFR 207.20 - Who must register and submit a drug list.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., preparation, propagation, compounding, or processing of an animal feed bearing or containing an animal drug (i... drug application, a new animal drug application, an abbreviated new animal drug application, a... 21 Food and Drugs 4 2011-04-01 2011-04-01 false Who must register and submit a drug list. 207.20...

  12. 21 CFR 207.20 - Who must register and submit a drug list.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., preparation, propagation, compounding, or processing of an animal feed bearing or containing an animal drug (i... drug application, a new animal drug application, an abbreviated new animal drug application, a... 21 Food and Drugs 4 2013-04-01 2013-04-01 false Who must register and submit a drug list. 207.20...

  13. Education-based health inequalities in 18,000 Norwegian couples: the Nord-Trøndelag Health Study (HUNT).

    PubMed

    Nilsen, Sara Marie; Bjørngaard, Johan Håkon; Ernstsen, Linda; Krokstad, Steinar; Westin, Steinar

    2012-11-19

    Education-based inequalities in health are well established, but they are usually studied from an individual perspective. However, many individuals are part of a couple. We studied education-based health inequalities from the perspective of couples where indicators of health were measured by subjective health, anxiety and depression. A sample of 35,980 women and men (17,990 couples) was derived from the Norwegian Nord-Trøndelag Health Study 1995-97 (HUNT 2). Educational data and family identification numbers were obtained from Statistics Norway. The dependent variables were subjective health (four-integer scale), anxiety (21-integer scale) and depression (21-integer scale), which were captured using the Hospital Anxiety and Depression Scale. The dependent variables were rescaled from 0 to 100 where 100 was the worst score. Cross-sectional analyses were performed using two-level linear random effect regression models. The variance attributable to the couple level was 42% for education, 16% for subjective health, 19% for anxiety and 25% for depression. A one-year increase in education relative to that of one's partner was associated with an improvement of 0.6 scale points (95% confidence interval = 0.5-0.8) in the subjective health score (within-couple coefficient). A one-year increase in a couple's average education was associated with an improvement of 1.7 scale points (95% confidence interval = 1.6-1.8) in the subjective health score (between-couple coefficient). There were no education-based differences in the anxiety or depression scores when partners were compared, whereas there were substantial education-based differences between couples in all three outcome measures. We found considerable clustering of education and health within couples, which highlighted the importance of the family environment. Our results support previous studies that report the mutual effects of spouses on education-based inequalities in health, suggesting that couples develop

  14. Analyzing the Impacts of Dams on Riparian Ecosystems: A Review of Research Strategies and Their Relevance to the Snake River Through Hells Canyon

    PubMed Central

    Braatne, Jeffrey H.; Goater, Lori A.; Blair, Charles L.

    2007-01-01

    River damming provides a dominant human impact on river environments worldwide, and while local impacts of reservoir flooding are immediate, subsequent ecological impacts downstream can be extensive. In this article, we assess seven research strategies for analyzing the impacts of dams and river flow regulation on riparian ecosystems. These include spatial comparisons of (1) upstream versus downstream reaches, (2) progressive downstream patterns, or (3) the dammed river versus an adjacent free-flowing or differently regulated river(s). Temporal comparisons consider (4) pre- versus post-dam, or (5) sequential post-dam conditions. However, spatial comparisons are complicated by the fact that dams are not randomly located, and temporal comparisons are commonly limited by sparse historic information. As a result, comparative approaches are often correlative and vulnerable to confounding factors. To complement these analyses, (6) flow or sediment modifications can be implemented to test causal associations. Finally, (7) process-based modeling represents a predictive approach incorporating hydrogeomorphic processes and their biological consequences. In a case study of Hells Canyon, the upstream versus downstream comparison is confounded by a dramatic geomorphic transition. Comparison of the multiple reaches below the dams should be useful, and the comparison of Snake River with the adjacent free-flowing Salmon River may provide the strongest spatial comparison. A pre- versus post-dam comparison would provide the most direct study approach, but pre-dam information is limited to historic reports and archival photographs. We conclude that multiple study approaches are essential to provide confident interpretations of ecological impacts downstream from dams, and propose a comprehensive study for Hells Canyon that integrates multiple research strategies. PMID:18043964

  15. THE LAST PURSUIT: The 2d Armored Division’s Exploitation from the Rhine to the Elbe, 24 March-14 April 1945,

    DTIC Science & Technology

    1984-05-23

    34 - .- " MacDonald, Charles B. The Last Offensive. Ryan, Cornelius The Last Battle. 6 . i Toland, Joyn The Last 100 Days. Trahan, E. History of the 2d...18. Weigley, Eisenhower’s Lieutenants, pp. 17-19. 19. Ibid. 20. Ibid. 21. Ian V. Hog, The Enccopedia of Infantry Weapons of World~~War II (New York...Hogg, Ian V., The Encyclopedia of Infantry Weapons of World War II . New York: Thomas Y. Crowell Company, 1977. Houston, Donald E., Hell on Wheels

  16. A kidney from hell? A nephrological view of the Whitechapel murders in 1888.

    PubMed

    Wolf, Gunter

    2008-10-01

    In the poor Whitechapel district of the East End of London in the fall of 1888, at least five prostitutes were brutally murdered, and in all but one case, also mutilated. The murderer was never caught and became known by his nickname 'Jack the Ripper'. The left kidney and the uterus were cut out and taken away from one of the victims named Catherine Eddowes. A kidney was also cut out of the body from another victim, but not taken away. Two weeks later, George Lusk, president of the Whitechapel Vigilance Committee, received a small cardboard box with half of a longitudinally divided kidney and a letter entitled 'From hell' claiming that the kidney inside the box was taken from the victim. The kidney was brought to Dr Thomas Horrocks Openshaw, the Curator of the London Pathological Museum, where the kidney could be microscopically examined. The press jumped on the topic and made a circumstantial case that this kidney had been indeed torn from the body of Catherine Eddowes. According to the later memoirs of Major Henry Smith of the City Police published more than 20 years after the incident, the kidney left in the corpse of Catherine Eddowes was in an advanced stage of Bright's disease and the kidney sent to George Lusk was in exactly a similar stage. Today, the majority of criminologists believe that the kidney sent to Mr Lusk was a hoax as were other letters signed with Jack the Ripper. However, the murderer took organs from his victims, and in the case of Catherine Eddowes, the kidney. Serial killers often mutilate their victims and abscond with the removed body parts as trophies. By removing the kidney from Catherine Eddowes, Jack the Ripper may have tried to take possession of the conscience, emotions and desires of one of his victims, attributes residing in the kidney as described in the Bible. Jack the Ripper was never caught; many suspects have been suggested, and the murder series ended as suddenly as it had begun. We will never know who this mentally

  17. Summary of the Border Infrastructure Finance Workshop : January 20-21, 2016, San Diego, California

    DOT National Transportation Integrated Search

    2016-02-01

    On January 20-21, 2016, the U.S.-Mexico Joint Working Committee for Transportation Planning (JWC), the Federal Highway Administration (FHWA), and the Secretariat of Communications and Transportation (SCT) sponsored a workshop on Border Infrastructure...

  18. Mineralized soft-tissue structure and chemistry in a mummified hadrosaur from the Hell Creek Formation, North Dakota (USA).

    PubMed

    Manning, Phillip L; Morris, Peter M; McMahon, Adam; Jones, Emrys; Gize, Andy; Macquaker, Joe H S; Wolff, George; Thompson, Anu; Marshall, Jim; Taylor, Kevin G; Lyson, Tyler; Gaskell, Simon; Reamtong, Onrapak; Sellers, William I; van Dongen, Bart E; Buckley, Mike; Wogelius, Roy A

    2009-10-07

    An extremely well-preserved dinosaur (Cf. Edmontosaurus sp.) found in the Hell Creek Formation (Upper Cretaceous, North Dakota) retains soft-tissue replacement structures and associated organic compounds. Mineral cements precipitated in the skin apparently follow original cell boundaries, partially preserving epidermis microstructure. Infrared and electron microprobe images of ossified tendon clearly show preserved mineral zonation, with silica and trapped carbon dioxide forming thin linings on Haversian canals within apatite. Furthermore, Fourier transform infrared spectroscopy (FTIR) of materials recovered from the skin and terminal ungual phalanx suggests the presence of compounds containing amide groups. Amino acid composition analyses of the mineralized skin envelope clearly differ from the surrounding matrix; however, intact proteins could not be obtained using protein mass spectrometry. The presence of endogenously derived organics from the skin was further demonstrated by pyrolysis gas chromatography mass spectrometry (Py-GCMS), indicating survival and presence of macromolecules that were in part aliphatic (see the electronic supplementary material).

  19. Mineralized soft-tissue structure and chemistry in a mummified hadrosaur from the Hell Creek Formation, North Dakota (USA)

    PubMed Central

    Manning, Phillip L.; Morris, Peter M.; McMahon, Adam; Jones, Emrys; Gize, Andy; Macquaker, Joe H. S.; Wolff, George; Thompson, Anu; Marshall, Jim; Taylor, Kevin G.; Lyson, Tyler; Gaskell, Simon; Reamtong, Onrapak; Sellers, William I.; van Dongen, Bart E.; Buckley, Mike; Wogelius, Roy A.

    2009-01-01

    An extremely well-preserved dinosaur (Cf. Edmontosaurus sp.) found in the Hell Creek Formation (Upper Cretaceous, North Dakota) retains soft-tissue replacement structures and associated organic compounds. Mineral cements precipitated in the skin apparently follow original cell boundaries, partially preserving epidermis microstructure. Infrared and electron microprobe images of ossified tendon clearly show preserved mineral zonation, with silica and trapped carbon dioxide forming thin linings on Haversian canals within apatite. Furthermore, Fourier transform infrared spectroscopy (FTIR) of materials recovered from the skin and terminal ungual phalanx suggests the presence of compounds containing amide groups. Amino acid composition analyses of the mineralized skin envelope clearly differ from the surrounding matrix; however, intact proteins could not be obtained using protein mass spectrometry. The presence of endogenously derived organics from the skin was further demonstrated by pyrolysis gas chromatography mass spectrometry (Py-GCMS), indicating survival and presence of macromolecules that were in part aliphatic (see the electronic supplementary material). PMID:19570788

  20. The 20Ne(d,p) 21Ne Transfer Reaction in Relation to the s-Process Abundances

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nsangu, C. T.; Laird, A. M.; Parikh, A.

    2016-01-01

    A study of the Ne-20(d,p)Ne-21 transfer reaction was performed using the Quadrupole Dipole Dipole Dipole (Q3D) magnetic spectrograph in Garching, Germany. The experiment probed excitation energies in Ne-21 ranging from 6.9 MeV to 8.5 MeV. The aim was to investigate the spectroscopic information of Ne-21 within the Gamow window of core helium burning in massive stars. Further information in this region will help reduce the uncertainties on the extrapolation down to Gamow window cross sections of the O-17(alpha,gamma)Ne-21 reaction. In low metallicity stars, this reaction has a direct impact on s-process abundances by determining the fate of O-16 as eithermore » a neutron poison or a neutron absorber. The experiment used a 22-MeV deuteron beam, with intensities varying from 0.5-1 mu A, and an implanted target of Ne-20 of 7 mu g/cm(2) in 40 mu g/cm(2) carbon foils. Sixteen Ne-21 peaks have been identified in the E-x = 6.9-8.5 MeV range, of which only thirteen peaks correspond to known states. Only the previously-known E-x = 7.960 MeV state was observed within the Gamow window.« less

  1. 21 CFR 607.20 - Who must register and submit a blood product list.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Who must register and submit a blood product list... BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.20 Who must register and submit a blood product list. (a) Owners or operators of all establishments, not exempt under...

  2. 21 CFR 607.20 - Who must register and submit a blood product list.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Who must register and submit a blood product list... BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.20 Who must register and submit a blood product list. (a) Owners or operators of all establishments, not exempt under...

  3. 21 CFR 607.20 - Who must register and submit a blood product list.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Who must register and submit a blood product list... BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.20 Who must register and submit a blood product list. (a) Owners or operators of all establishments, not exempt under...

  4. 21 CFR 607.20 - Who must register and submit a blood product list.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Who must register and submit a blood product list... BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.20 Who must register and submit a blood product list. (a) Owners or operators of all establishments, not exempt under...

  5. 21 CFR 607.20 - Who must register and submit a blood product list.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 7 2011-04-01 2010-04-01 true Who must register and submit a blood product list... BLOOD AND BLOOD PRODUCTS Procedures for Domestic Blood Product Establishments § 607.20 Who must register and submit a blood product list. (a) Owners or operators of all establishments, not exempt under...

  6. [From the glorious time of homeopathy medicine chests in Nord-Schleswing (South Justland) about 1900].

    PubMed

    Marckmann, Anton

    2003-01-01

    The article deals with the origin, background and development of homoeopathy over a hundred years span, beginning with its "invention" in the early 19th century (Hahnemann). Leipzig became a center for a huge production of homoeopathic remedies through Dr. W. Schwabe's "Central-Apoteke", founded in 1878, with customers all over the world. The preparation of around one thousand products were described in 1880 in Schwabes "Pharmacopoea homoeopatica polyglotta", in five languages, and this article gives a survey of the principles in the production of the final remedies which were distributed as Schwabes homoeopatic house-chests of many varieties, containing from a few up to more than hundred bottles. Detailed instructions and guidance in the applications of the content of these popular and wide-spread chests were available for laymen from hand-books. However their use vanished gradually in the third decade of the 20th century and later, and the chests were either destroyed or put away. This was also true for the situation in South Jutland (before 1920 a german province called Nord Schleswig), nevertheless the author's research succeeded in detecting thirteen homoeopathic house-chests from the region, purchased about year 1900. An attempt is made to throw light on their origin, their use and their users at a time, when homoeopathy played a role for layman in the treatment of diseases, outside the authorized health service - or as a supplement to this.

  7. La tectonique active de la région nord-algérienne

    NASA Astrophysics Data System (ADS)

    Yelles-Chaouche, AbdelKrim; Boudiaf, Azzedine; Djellit, Hamou; Bracene, Rabah

    2006-01-01

    En Algérie, la tectonique active est localisée dans la région nord du pays, essentiellement dans le Tell. Dans cette région, frontière entre les plaques Africaine et Eurasiatique, la déformation tectonique est l'expression de la convergence actuelle des ces deux plaques et se traduit par la fermeture progressive des bassins néogènes et par la poursuite de l'édification de la chaîne. Le long de la marge, la déformation s'exprime dans la partie de la plaine abyssale proche du continent, par le plissement de la couverture plio-quaternaire. Au niveau de la pente et sur le plateau continental, la sismicité est générée par des accidents qui se prolongent parfois à terre. Cette tectonique littorale active est à l'origine de la surrection de la côte, comme cela fut le cas lors du dernier séisme de Boumerdes du 21 mai 2003, où le soulèvement cosismique a été estimé en moyenne à 0,50 m. À terre, la sismicité s'exprime surtout le long des bordures des bassins néogènes qui longent la côte. Ces bassins se déforment en donnant des structures plicatives (synclinaux, anticlinaux) et parfois cassantes (pli-failles, failles inverses, chevauchements) orientées NE-SW à NNE-SSW. Ces dernières sont le plus souvent à l'origine des violents tremblements de terre que connaît l'Algérie. Plus au sud, la sismicité s'exprime, tout le long du Tell, le long des faisceaux de plis de direction NE-SW. Actuellement, dans les régions des Hauts Plateaux et la région de l'Atlas saharien, l'activité sismique est faible. Pour citer cet article : A. Yelles-Chaouche et al., C. R. Geoscience 338 (2006).

  8. Interim Letter Report - Verification Survey of Partial Grids H19, J21, J22, X20, and X21 at the David Witherspoon, Inc. 1630 Site, Knoxville Tennessee

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    P.C. Weaver

    2008-03-19

    Conduct verification surveys of available grids at the David Witherspoon Incorporated 1630 Site (DWI 1630) in Knoxville, Tennessee. The IVT conducted verification activities of partial grids H19, J21, J22, X20, and X21.

  9. 21 CFR 1005.20 - Hearing.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... application for permission to perform such action as is necessary to bring the product into compliance with the Act, such application shall include the information required by § 1005.21. (c) If the application... such application. ...

  10. 21 CFR 20.114 - Data and information submitted pursuant to cooperative quality assurance agreements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Records § 20.114 Data and information submitted pursuant to cooperative quality assurance agreements. Data and information submitted to the Food and Drug Administration pursuant to a cooperative quality... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Data and information submitted pursuant to...

  11. 21 CFR 20.114 - Data and information submitted pursuant to cooperative quality assurance agreements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Records § 20.114 Data and information submitted pursuant to cooperative quality assurance agreements. Data and information submitted to the Food and Drug Administration pursuant to a cooperative quality... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Data and information submitted pursuant to...

  12. 21 CFR 20.114 - Data and information submitted pursuant to cooperative quality assurance agreements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Records § 20.114 Data and information submitted pursuant to cooperative quality assurance agreements. Data and information submitted to the Food and Drug Administration pursuant to a cooperative quality... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Data and information submitted pursuant to...

  13. 21 CFR 20.114 - Data and information submitted pursuant to cooperative quality assurance agreements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Records § 20.114 Data and information submitted pursuant to cooperative quality assurance agreements. Data and information submitted to the Food and Drug Administration pursuant to a cooperative quality... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Data and information submitted pursuant to...

  14. Geology, geochronology, and potential volcanic hazards in the Lava Ridge-Hells Half Acre area, eastern Snake River Plain, Idaho

    USGS Publications Warehouse

    Kuntz, Mel A.; Dalrymple, G. Brent

    1979-01-01

    The evaluation of volcanic hazards for the proposed Safety Test Reactor Facility (STF) at the Argonne National Laboratory-West (ANLW) site, Idaho National Engineering Laboratory (INEL), Idaho, involves an analysis of the geology of the Lava Ridge-Hells Half Acre area and of K-At age determinations on lava flows in cored drill holes. The ANLW site at INEL lies in a shallow topographic depression bounded on the east and south by volcanic rift zones that are the locus of past shield-type basalt volcanism and by rhyolite domes erupted along the ring fracture of an inferred rhyolite caldera. The K-At age data indicate that the ANLW site has been flooded by basalt lava flows at irregular intervals from perhaps a few thousand years to as much as 300,000-400,000 years, with an average recurrence interval between flows of approximately 80,000-100,000 years. At least five major lava flows have covered the ANLW site within the past 500,000 years.

  15. Education-based health inequalities in 18,000 Norwegian couples: the Nord-Trøndelag Health Study (HUNT)

    PubMed Central

    2012-01-01

    Background Education-based inequalities in health are well established, but they are usually studied from an individual perspective. However, many individuals are part of a couple. We studied education-based health inequalities from the perspective of couples where indicators of health were measured by subjective health, anxiety and depression. Methods A sample of 35,980 women and men (17,990 couples) was derived from the Norwegian Nord-Trøndelag Health Study 1995–97 (HUNT 2). Educational data and family identification numbers were obtained from Statistics Norway. The dependent variables were subjective health (four-integer scale), anxiety (21-integer scale) and depression (21-integer scale), which were captured using the Hospital Anxiety and Depression Scale. The dependent variables were rescaled from 0 to 100 where 100 was the worst score. Cross-sectional analyses were performed using two-level linear random effect regression models. Results The variance attributable to the couple level was 42% for education, 16% for subjective health, 19% for anxiety and 25% for depression. A one-year increase in education relative to that of one’s partner was associated with an improvement of 0.6 scale points (95% confidence interval = 0.5–0.8) in the subjective health score (within-couple coefficient). A one-year increase in a couple’s average education was associated with an improvement of 1.7 scale points (95% confidence interval = 1.6–1.8) in the subjective health score (between-couple coefficient). There were no education-based differences in the anxiety or depression scores when partners were compared, whereas there were substantial education-based differences between couples in all three outcome measures. Conclusions We found considerable clustering of education and health within couples, which highlighted the importance of the family environment. Our results support previous studies that report the mutual effects of spouses on education

  16. 21 CFR 530.20 - Conditions for permitted extralabel animal and human drug use in food-producing animals.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... illegal drug residues occur in any food-producing animal subjected to extralabel treatment. (b) The... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Conditions for permitted extralabel animal and human drug use in food-producing animals. 530.20 Section 530.20 Food and Drugs FOOD AND DRUG...

  17. 21 CFR 530.20 - Conditions for permitted extralabel animal and human drug use in food-producing animals.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... illegal drug residues occur in any food-producing animal subjected to extralabel treatment. (b) The... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Conditions for permitted extralabel animal and human drug use in food-producing animals. 530.20 Section 530.20 Food and Drugs FOOD AND DRUG...

  18. 21 CFR 530.20 - Conditions for permitted extralabel animal and human drug use in food-producing animals.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... illegal drug residues occur in any food-producing animal subjected to extralabel treatment. (b) The... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Conditions for permitted extralabel animal and human drug use in food-producing animals. 530.20 Section 530.20 Food and Drugs FOOD AND DRUG...

  19. 21 CFR 530.20 - Conditions for permitted extralabel animal and human drug use in food-producing animals.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... illegal drug residues occur in any food-producing animal subjected to extralabel treatment. (b) The... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Conditions for permitted extralabel animal and human drug use in food-producing animals. 530.20 Section 530.20 Food and Drugs FOOD AND DRUG...

  20. Hierarchical and chemical space partitioning in new intermetallic borides MNi21B20 (M = In, Sn).

    PubMed

    Wagner, Frank R; Zheng, Qiang; Gumeniuk, Roman; Bende, David; Prots, Yurii; Bobnar, Matej; Hu, Dong-Li; Burkhardt, Ulrich; Grin, Yuri; Leithe-Jasper, Andreas

    2017-10-10

    The compounds MNi 21 B 20 (M = In, Sn) have been synthesized and their cubic crystal structure determined (space group Pm3[combining macron]m, lattice parameters a = 7.1730(1) Å and a = 7.1834(1) Å, respectively). The structure can be described as a hierarchical partitioning of space based on a reo-e net formed by Ni3 species with large cubical, cuboctahedral and rhombicuboctahedral voids being filled according to [Ni1@Ni3 8 ], [M@Ni3 12 ], and [Ni2 6 @B 20 @Ni3 24 ], respectively. The [Ni 6 @B 20 ] motif inside the rhombicuboctahedral voids features an empty [Ni 6 ] octahedron surrounded by a [B 20 ] cage recently described in E 2 Ni 21 B 20 (E = Zn, Ga). Position-space bonding analysis using ELI-D and QTAIM space partitioning as well as 2- and 3-center delocalization indices gives strong support to an alternative chemical description of space partitioning based on face-condensed [B@Ni 6 ] trigonal prisms as basic building blocks. The shortest B-B contacts display locally nested 3-center B-B-Ni bonding inside each trigonal prism. This clearly rules out the notion of [Ni 6 @B 20 ] clusters and leads to the arrangement of 20 face-condensed [B@Ni2 3 Ni3 3 ] trigonal prisms resulting in a triple-shell like situation Ni2 6 @B 20 @Ni3 24 (reo-e), where the shells display comparable intra- and inter-shell bonding. Both compounds are Pauli paramagnets displaying metallic conductivity.

  1. Medical Surveillance Monthly Report (MSMR). Volume 20, Number 7

    DTIC Science & Technology

    2013-07-01

    involves social support, education, group therapy, mind- body medicine, virtual reality , hypnosis , spiritual counseling, cognitive behavioral therapy...deaths of innocent civilians including children. Sometimes the reality of what these service members have experienced is inde- scribable and usually...Th is month’s edition of the MSMR highlights the stark reality that “war is hell.” Forceful and intense physical and mental stress is a natural

  2. Archive of digital chirp subbottom profile data collected during USGS Cruise 13GFP01, Brownlee Dam and Hells Canyon Reservoir, Idaho and Oregon, 2013

    USGS Publications Warehouse

    Forde, Arnell S.; Dadisman, Shawn V.; Flocks, James G.; Fosness, Ryan L.; Welcker, Chris; Kelso, Kyle W.

    2014-01-01

    From March 16 - 31, 2013, the U.S. Geological Survey in cooperation with the Idaho Power Company conducted a geophysical survey to investigate sediment deposits and long-term sediment transport within the Snake River from Brownlee Dam to Hells Canyon Reservoir, along the Idaho and Oregon border; this effort will help the USGS to better understand geologic processes. This report serves as an archive of unprocessed digital chirp subbottom data, trackline maps, navigation files, Geographic Information System (GIS) files, Field Activity Collection System (FACS) logs, and formal Federal Geographic Data Committee (FGDC) metadata. Gained (showing a relative increase in signal amplitude) digital images of the seismic profiles are also provided. Refer to the Acronyms page for expansions of acronyms and abbreviations used in this report.

  3. Historical and Projected Surface Temperature over India during the 20th and 21st century.

    PubMed

    Basha, Ghouse; Kishore, P; Ratnam, M Venkat; Jayaraman, A; Agha Kouchak, Amir; Ouarda, Taha B M J; Velicogna, Isabella

    2017-06-07

    Surface Temperature (ST) over India has increased by ~0.055 K/decade during 1860-2005 and follows the global warming trend. Here, the natural and external forcings (e.g., natural and anthropogenic) responsible for ST variability are studied from Coupled Model Inter-comparison phase 5 (CMIP5) models during the 20 th century and projections during the 21 st century along with seasonal variability. Greenhouse Gases (GHG) and Land Use (LU) are the major factors that gave rise to warming during the 20 th century. Anthropogenic Aerosols (AA) have slowed down the warming rate. The CMIP5 projection over India shows a sharp increase in ST under Representative Concentration Pathways (RCP) 8.5 where it reaches a maximum of 5 K by the end of the 21 st century. Under RCP2.6 emission scenarios, ST increases up to the year 2050 and decreases afterwards. The seasonal variability of ST during the 21 st century shows significant increase during summer. Analysis of rare heat and cold events for 2080-2099 relative to a base period of 1986-2006 under RCP8.5 scenarios reveals that both are likely to increase substantially. However, by controlling the regional AA and LU change in India, a reduction in further warming over India region might be achieved.

  4. Alcohol consumption is associated with reduced risk of Type 2 diabetes and autoimmune diabetes in adults: results from the Nord-Trøndelag health study.

    PubMed

    Rasouli, B; Ahlbom, A; Andersson, T; Grill, V; Midthjell, K; Olsson, L; Carlsson, S

    2013-01-01

    We investigated the influence of different aspects of alcohol consumption on the risk of Type 2 diabetes and autoimmune diabetes in adults. We used data from the Nord-Trøndelag Health Survey (HUNT) study, in which all adults aged ≥ 20 years from Nord-Trondelag County were invited to participate in three surveys in 1984-1986, 1995-1997 and 2006-2008. Patients with diabetes were identified using self-reports, and participants with onset age ≥ 35 years were classified as having Type 2 diabetes if they were negative for anti-glutamic acid decarboxylase (n = 1841) and as having autoimmune diabetes if they were positive for anti-glutamic acid decarboxylase (n = 140). Hazard ratios of amount and frequency of alcohol use, alcoholic beverage choice, and binge drinking and alcohol use disorders were estimated. Moderate alcohol consumption (adjusted for confounders) was associated with a reduced risk of Type 2 diabetes in men, but not in women (hazard ratio for men 10-15 g/day 0.48, 95% CI 0.28-0.77; hazard ratio for women ≥ 10 g/day 0.81, 95% CI 0.33-1.96). The reduced risk was primarily linked to consumption of wine [hazard ratio 0.93, 95% CI 0.87-0.99 (per g/day)]. No increased risk was seen in participants reporting binge drinking or in problem drinkers. The results were also compatible with a reduced risk of autoimmune diabetes associated with alcohol consumption [hazard ratio 0.70, 95% CI 0.45-1.08 (frequent consumption) and hazard ratio 0.36, 95% CI 0.13-0.97 (2-7 g/day)]. Moderate alcohol consumption associates with reduced risk of both Type 2 diabetes and autoimmune diabetes. A protective effect of alcohol intake may be limited to men. High alcohol consumption does not seem to carry an increased risk of diabetes. © 2012 The Authors. Diabetic Medicine © 2012 Diabetes UK.

  5. Bleeding pattern with drospirenone 3 mg+ethinyl estradiol 20 mcg 24/4 combined oral contraceptive compared with desogestrel 150 mcg+ethinyl estradiol 20 mcg 21/7 combined oral contraceptive.

    PubMed

    Anttila, Leena; Kunz, Michael; Marr, Joachim

    2009-11-01

    The study was conducted to compare cycle control, bleeding pattern and efficacy of two low-dose combined oral contraceptives. Four hundred fifty-three women were randomized to receive a 24/4 regimen of drospirenone 3 mg/ethinyl estradiol 20 mcg (drsp 3 mg/EE 20 mcg; n=230) or a 21/7 regimen of desogestrel 150 mcg/EE 20 mcg (DSG 150 mcg/EE 20 mcg; n=223), and recorded bleeding daily over 7 treatment cycles. The duration [mean 4.7 (SD 1.5)-5.2 (SD 2.2) days in the drsp 3 mg/EE 20 mcg 24/4 group and 5.1 (SD 1.5)-5.4 (SD 2.1) days in the DSG 150 mcg/ EE 20 mcg group] and maximum intensity ("normal bleeding" for >50% of all subjects) of scheduled bleeding in Cycles 1-6 was comparable between treatment groups. The incidence of unscheduled bleeding during Cycles 2-6 was also similar between the two groups (drsp 3 mg/EE 20 mcg, 8.8-17.3%; DSG 150 mcg/ EE 20 mcg, 9.4-16.3%). Drsp 3 mg/EE 20 mcg 24/4 achieved an acceptable bleeding profile with reliable cycle control, comparable with an established formulation.

  6. Mental health and wellbeing in spouses of persons with dementia: the Nord-Trøndelag Health Study.

    PubMed

    Ask, Helga; Langballe, Ellen Melbye; Holmen, Jostein; Selbæk, Geir; Saltvedt, Ingvild; Tambs, Kristian

    2014-05-01

    Caring for a spouse diagnosed with dementia can be a stressful situation and can put the caregiving partner at risk of loss of mental health and wellbeing. The main aim of this study was to investigate the relationship between dementia and spousal mental health in a population-based sample of married couples older than 55 years of age. The association was investigated for individuals living together with their demented partner, as well as for individuals whose demented partner was living in an institution. Data on dementia were collected from hospitals and nursing homes in the county of Nord-Trøndelag, Norway. These data were combined with data on spousal mental health, which were collected in a population-based health screening: the Nord-Trøndelag Health Study (HUNT). Of 6,951 participating couples (>55 years), 131 included one partner that had been diagnosed with dementia. Our results indicate that after adjustment for covariates, having a partner with dementia is associated with lower levels of life satisfaction and more symptoms of anxiety and depression than reported by spouses of elderly individuals without dementia. Spouses living together with a partner diagnosed with dementia experienced moderately lower levels of life satisfaction (0.35 standard deviation [SD]) and more symptoms of depression (0.38 SD) and anxiety (0.23 SD) than did their non-caregiving counterparts. Having a partner with dementia that resided in a nursing home was associated with clearly lower life satisfaction. Compared with non-caregivers, these spouses reported lower levels of life satisfaction (1.16 SD), and also more symptoms of depression (0.38 SD), and more symptoms of anxiety (0.42 SD). Having a partner with dementia is associated with loss of mental health and reduced life satisfaction. The risk of adverse mental health outcomes is greatest after the partner's nursing home admission.

  7. Ionospheric convection during the magnetic storm of 20-21 March 1991

    NASA Technical Reports Server (NTRS)

    Taylor, J. R.; Yeoman, T. K.; Lester, M.; Buonsanto, M. J.; Scali, J. L.; Ruohoniemi, J. M.; Kelly, J. D.

    1994-01-01

    We report on the response of high-latitude ionospheric convection during the magnetic storm of March 20-21 1990. IMP-8 measurements of solar wind plasma and interplanetary magnetic field (IMF), ionospheric convection flow measurements from the Wick and Goose Bay coherent radars, EISCAT, Millstone Hill and Sondrestorm incoherent radars and three digisondes at Millstone Hill, Goose Bay and Qaanaaq are presented. Two intervals of particular interest have been indentified. The first starts with a storm sudden commencement at 2243 UT on March 20 and includes the ionospheric activity in the following 7 h. The response time of the ionospheric convection to the southward tuning of the IMF in the dusk to midnight local times is found to be approximately half that measured in a similar study at comparable local times during more normal solar wind conditions. A subsequent reconfiguration of the nightside convection pattern was also observed, although it was not possible to distinguish between effects due to possible changes in B(sub y) and effects due to substorm activity. The second interval, 1200-2100 UT 21 March 1990, included a southward turning of the IMF which resulted in the B(sub z) component becoming -10 nT. The response time on the dayside to this change in the IMF at the magnetopause was approximately 15 min to 30 min which is a factor of approximately 2 greater than those previously measured at higher latitudes. A movement of the nightside flow reversal, possibly driven by current systems associated with the substorm expansion phases, was observed, implying that the nightside convection pattern can be dominated by substorm activity.

  8. 21 CFR 20.84 - Disclosure to consultants, advisory committees, State and local government officials commissioned...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... the same restrictions with respect to the disclosure of such data and information as any other Food... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Disclosure to consultants, advisory committees... AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.84 Disclosure to...

  9. 21 CFR 20.84 - Disclosure to consultants, advisory committees, State and local government officials commissioned...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... the same restrictions with respect to the disclosure of such data and information as any other Food... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Disclosure to consultants, advisory committees... AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.84 Disclosure to...

  10. 21 CFR 20.84 - Disclosure to consultants, advisory committees, State and local government officials commissioned...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the same restrictions with respect to the disclosure of such data and information as any other Food... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Disclosure to consultants, advisory committees... AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.84 Disclosure to...

  11. 21 CFR 20.84 - Disclosure to consultants, advisory committees, State and local government officials commissioned...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... the same restrictions with respect to the disclosure of such data and information as any other Food... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Disclosure to consultants, advisory committees... AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.84 Disclosure to...

  12. 21 CFR 20.84 - Disclosure to consultants, advisory committees, State and local government officials commissioned...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... the same restrictions with respect to the disclosure of such data and information as any other Food... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Disclosure to consultants, advisory committees... AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.84 Disclosure to...

  13. 21 CFR 20.106 - Studies and reports prepared by or with funds provided by the Food and Drug Administration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Categories of Records § 20.106 Studies and reports prepared by or with funds provided by the Food and Drug... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Studies and reports prepared by or with funds provided by the Food and Drug Administration. 20.106 Section 20.106 Food and Drugs FOOD AND DRUG...

  14. 17,20β,21-Trihydroxy-4-pregnen-3-one biosynthesis and 20β-hydroxysteroid dehydrogenase expression during final oocyte maturation in the protandrous yellowfin porgy, Acanthopagrus latus.

    PubMed

    Jeng, Shan-Ru; Yueh, Wen-Shiun; Lee, Yan-Horn; Yen, Hsiu-Fang; Chang, Ching-Fong

    2012-04-01

    The purpose of this study was to investigate the physiological maturation-inducing steroid (MIS) in the marine protandrous yellowfin porgy (Acanthopagrus latus). Female fish were injected with 2 doses of LHRH analog (10 and 40 μg per kg). Ovarian tissue was obtained at 6 h intervals for in vitro analysis of oocyte maturation. The most effective steroids for inducing in vitro maturation (germinal vesicle breakdown and GVBD) in cultured oocytes were 17,20β-dihydroxy-4-pregnen-3-one (17,20βP) and 17,20β,21-trihydroxy-4-pregnen-3-one (20β-S). 17,20βP was less potent than 20βS in inducing oocyte maturation. At higher concentrations, 11-deoxycortisol, 17α-hydroxy-progesterone, and 20β-21-dihydroxy-4-pregnen-3-one also significantly induced oocyte maturation. A tritiated precursor [(3)H]-pregnenolone, was cultured in vitro together with the maturing ovarian tissue. The tritiated metabolites were purified and identified by solvent extraction, HPLC, TLC, acetylation reaction and recrystallization. HPLC, TLC and recrystallization analysis showed that significant levels of tritiated 11-deoxycortisol (a precursor of 20β-S) and 20β-S, but not 17,20βP, were biosynthesized from [(3)H]-pregnenolone. Similar TLC profiles were obtained from the tritiated products that were isolated from the HPLC/TLC 20β-S fraction and standard 20β-S after the acetylation reaction. Constant specific radioactivity of tritiated 11-deoxycortisol and 20β-S but not 17,20βP by recrystallization was obtained in the tritiated metabolites isolated from HPLC and TLC fractions. The expression of 20β-hydroxysteroid dehydrogenase (20β-HSD) mRNA (a key enzyme that converts 11-deoxycortisol to 20β-S) was significantly increased in maturing ovarian tissue. This study provides the first evidence that 20β-S is converted from 11-deoxycortisol and is the possible MIS in yellowfin porgy. Copyright © 2012. Published by Elsevier Inc.

  15. 21 CFR 20.91 - Use of data or information for administrative or court enforcement action.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Use of data or information for administrative or... HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.91 Use of data or... the Food and Drug Administration from using any data or information, whether obtained voluntarily or...

  16. 21 CFR 20.91 - Use of data or information for administrative or court enforcement action.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Use of data or information for administrative or... HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.91 Use of data or... the Food and Drug Administration from using any data or information, whether obtained voluntarily or...

  17. 21 CFR 20.91 - Use of data or information for administrative or court enforcement action.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Use of data or information for administrative or... HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.91 Use of data or... the Food and Drug Administration from using any data or information, whether obtained voluntarily or...

  18. 21 CFR 20.91 - Use of data or information for administrative or court enforcement action.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Use of data or information for administrative or... HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.91 Use of data or... the Food and Drug Administration from using any data or information, whether obtained voluntarily or...

  19. 21 CFR 20.91 - Use of data or information for administrative or court enforcement action.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Use of data or information for administrative or... HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Limitations on Exemptions § 20.91 Use of data or... the Food and Drug Administration from using any data or information, whether obtained voluntarily or...

  20. 21 CFR 101.44 - What are the 20 most frequently consumed raw fruits, vegetables, and fish in the United States?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false What are the 20 most frequently consumed raw... raw fruits, vegetables, and fish in the United States? (a) The 20 most frequently consumed raw fruits..., and watermelon. (b) The 20 most frequently consumed raw vegetables are: Asparagus, bell pepper...

  1. 21 CFR 101.44 - What are the 20 most frequently consumed raw fruits, vegetables, and fish in the United States?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false What are the 20 most frequently consumed raw... raw fruits, vegetables, and fish in the United States? (a) The 20 most frequently consumed raw fruits..., and watermelon. (b) The 20 most frequently consumed raw vegetables are: Asparagus, bell pepper...

  2. 21 CFR 20.111 - Data and information submitted voluntarily to the Food and Drug Administration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... in a way that does not reveal data or information which is not available for public disclosure under... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Data and information submitted voluntarily to the... Records § 20.111 Data and information submitted voluntarily to the Food and Drug Administration. (a) The...

  3. 26 CFR 20.2041-2 - Powers of appointment created on or before October 21, 1942.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... estate for the reason that the power will not be treated as having been exercised. Example (4). A... 26 Internal Revenue 14 2010-04-01 2010-04-01 false Powers of appointment created on or before... Gross Estate § 20.2041-2 Powers of appointment created on or before October 21, 1942. (a) In general...

  4. Parental occupational exposure to solvents and heavy metals and risk of developing testicular germ cell tumors in sons (NORD-TEST Denmark).

    PubMed

    Olsson, Ann; Togawa, Kayo; Schüz, Joachim; Le Cornet, Charlotte; Fervers, Beatrice; Oksbjerg Dalton, Susanne; Pukkala, Eero; Feychting, Maria; Skakkebæk, Niels Erik; Hansen, Johnni

    2018-06-07

    Objective The present study aims to assess if parental occupational exposure to solvents or heavy metals is associated with risk of testicular germ cell tumors (TGCT) in sons in Denmark. Methods The NORD-TEST Denmark included 3421 cases diagnosed with TGCT at ages 14-49 years in Denmark between 1981 and 2014. Controls (N=14 024) selected from the central population registry were matched to cases on birth year. The Danish Supplementary Pension Fund provided parental occupational information. A job-exposure matrix was used to assign exposures, and conditional logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (CI). Results The overall analyses showed no significant associations except for paternal exposure to a sub-group of "heavy metal(s) and solvent(s)" (OR 1.50, 95% CI 1.01-2.24). Most fathers in this category had worked in wood related jobs and were assigned exposure to chromium VI and toluene. Other sub-group analyses suggested that maternal exposure to aromatic hydrocarbon were associated with TGCT risk, in sons born in 1970-1979, and to heavy metals (chromium, iron and nickel) in sons born in 1980-1998. Conclusion NORD-TEST Denmark provides no strong support for an association between parental exposures to solvents or heavy metals and TGCT in sons, and only weak support for an association between paternal exposure to chromium and toluene and TGCT risk in sons.

  5. [Consistency study of PowerPlex 21 kit and Goldeneye 20A kit and forensic application].

    PubMed

    Ren, He; Liu, Ying; Zhang, Qing-Xia; Jiao, Zhang-Ping

    2014-06-01

    To ensure the consistency of genotype results for PowerPlex 21 kit and Goldeneye 20A kit. The STR loci were amplified in DNA samples from 205 unrelated individuals in Beijing Han population. And consistency of 19 overlap STR loci typing were observed. The genetic polymorphism of D1S1656 locus was obtained. All 19 overlap loci typing showed consistent. The proportion of peak height of heterozygous loci in two kits showed no statistical difference (P > 0.05). The observed heterozygosis of D1S1656 was 0.878. The discrimination power was 0.949. The excluding probability of paternity of triplet was 0.751. The excluding probability of paternity of diploid was 0.506. The polymorphism information content was 0.810. PowerPlex 21 kit and Goldeneye 20A kit present a good consistency. The primer design is reasonable. The polymorphism of D1S1656 is good. The two kits can be used for human genetic analysis, paternity test, and individual identification in forensic practice.

  6. p21WAF1 and tumourigenesis: 20 years after.

    PubMed

    Warfel, Noel A; El-Deiry, Wafik S

    2013-01-01

    This review provides an overview of the structure, regulation and physiological functions of p21, the product of the cyclin-dependent kinase inhibitor 1A (CDKN1A) gene, with a focus on its dual role in promoting and repressing biological processes that are hallmarks of tumourigenesis. Recent work has provided a better understanding of the molecular mechanisms of how oncogenic signalling pathways influence p21 expression. In response to cellular stimuli, p21 expression is tightly regulated at transcriptional and post-translational levels through mechanisms involving RNA stabilization, phosphorylation and ubiquitination. As a result, growing evidence reveals that several important tumour suppressor and oncogenic signalling pathways alter p21 expression to elicit their effects on cell cycle progression and survival. Thus, p21 expression can both promote and inhibit tumourigenic processes, depending on the cellular context. Since its discovery, it has become increasingly clear that p21 can function as both a classical tumour suppressor and an oncogene. In order to effectively utilize p21 as a therapeutic target, it will be necessary to design therapeutic strategies that preferentially block the ability of p21 to promote senescence, stem cell renewal and cyclin/CDK activation, while leaving its tumour suppressive functions intact.

  7. Potentially inappropriate medication prescribing is associated with socioeconomic factors: a spatial analysis in the French Nord-Pas-de-Calais Region.

    PubMed

    Beuscart, Jean-Baptiste; Genin, Michael; Dupont, Corrine; Verloop, David; Duhamel, Alain; Defebvre, Marguerite-Marie; Puisieux, François

    2017-07-01

    potentially inappropriate medication (PIM) prescribing is common in older people and leads to adverse events and hospital admissions. to determine whether prevalence of PIM prescribing varies according to healthcare supply and socioeconomic status. all prescriptions dispensed at community pharmacies for patients aged 75 and older between 1 January  and 31 March 2012 were retrieved from French Health Insurance Information System of the Nord-Pas-de-Calais Region for patients affiliated to the Social Security scheme. PIM was defined according to the French list of Laroche. The geographic distribution of PIM prescribing in this area was analysed using spatial scan statistics. overall, 65.6% (n = 207,979) of people aged 75 years and over living in the Nord-Pas-de-Calais Region were included. Among them, 32.6% (n = 67,863) received at least one PIM. The spatial analysis identified 16 and 10 clusters of municipalities with a high and a low prevalence of PIM prescribing, respectively. Municipalities with a low prevalence of PIM were characterised by a high socioeconomic status whereas those with a high prevalence of PIM were mainly characterised by a low socioeconomic status, such as a high unemployment rate and low household incomes. Markers of healthcare supply were weakly associated with high or low prevalence clusters. significant geographic variation in PIM prescribing was observed in the study territory and was mainly associated with socioeconomic factors. © The Author 2017. Published by Oxford University Press on behalf of the British Geriatrics Society.All rights reserved. For permissions, please email: journals.permissions@oup.com

  8. Phase stability, crystal structure and magnetism in (U1-xNbx)2 Ni21B6 and (UyNb1-y)3Ni20B6

    NASA Astrophysics Data System (ADS)

    Provino, Alessia; Bhattacharya, Amitava; Dhar, Sudesh K.; Pani, Marcella; Gatti, Flavio; Paudyal, Durga; Manfrinetti, Pietro

    Ternary phases with composition T2M21X6 and T3M20X6 (T = transition metal; M = 3 d metal; X = B, C, P) are reported to crystallize with the W2Cr21C6-type and Mg3Ni20B6-type, respectively (ternary ordered derivatives of the cubic Cr23C6-type, cF116). They attract interest due to their refractory, mechanical, and peculiar magnetic properties. Literature data on these compounds only concern apparently stoichiometric 2:21:6 and 3:20:6 phases. Often only nominal composition has been reported, with few structural refinements and no measurements of physical properties. Lack of detailed stoichiometry and crystallographic data does not allow sufficient understanding of the crystal chemistry and properties of these compounds. We studied stability, crystal structure and magnetism of (U1-xNbx)2 Ni21B6 and (UyNb1-y)3Ni20B6; stable phases are U2Ni21B6 and Nb3Ni20B6, as also confirmed by theoretical calculations. The two pristine compounds solubilize Nb and U, respectively, up to a given extent. The substitution of U by Nb leads to a structural change from the W2Cr21C6- to the Mg3Ni20B6-type. While U2Ni21B6 is a Pauli paramagnet (itinerant non-magnetic state of U-5 f electrons), in agreement with literature, magnetization data for (UyNb1-y)3 Ni20B6 show itinerant ferromagnetism with TC >300 K.

  9. 18 CFR 35.21 - Applicability to licensees and others subject to section 19 or 20 of the Federal Power Act.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Applicability to licensees and others subject to section 19 or 20 of the Federal Power Act. 35.21 Section 35.21 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS...

  10. Determination of 20Ne(p ,γ )21Na cross sections from Ep=500 -2000 keV

    NASA Astrophysics Data System (ADS)

    Lyons, S.; Görres, J.; deBoer, R. J.; Stech, E.; Chen, Y.; Gilardy, G.; Liu, Q.; Long, A. M.; Moran, M.; Robertson, D.; Seymour, C.; Vande Kolk, B.; Wiescher, M.; Best, A.

    2018-06-01

    Background: The reaction 20Ne(p ,γ )21Na influences the nucleosynthesis of Ne, Na, and Mg isotopes while contributing to hydrogen burning in several stellar sites, such as red giants, asymptotic giant branch (AGB) stars, massive stars, and oxygen-neon (ONe) novae. In the relevant temperature range for these environments (T = 0.05-0.5 GK), the main contributions to this reaction rate are from the direct capture process as well as the high-energy tail of a subthreshold resonance in the ground-state transition at Ex = 2425 keV in the 21Na compound nucleus. Purpose: The previous measurement of this reaction reports cross sections with large uncertainties for the ground-state transition. At higher energies, where the subthreshold resonance makes a smaller contribution to the total cross section, only upper limits are provided. This work aims to reduce the uncertainty in the cross section where direct capture dominates, as well as provide cross-section data in previously unmeasured regions. Method: The 20Ne(p ,γ )21Na reaction was measured over a wide proton energy range (Ep = 0.5-2.0 MeV) at θlab = 90∘. Transitions to the ground state and to the 332 and 2425 keV excited states were observed. The primary transitions to these three bound states were utilized in an R -matrix analysis to determine the contributions of the direct capture and the subthreshold resonance to the total cross section. Results: The cross sections of the present measurements have been found to be in good agreement with the previous data at low energy. Significantly improved cross-section measurements have been obtained over the Ep = 1300-1900 keV region. The narrow resonance at Ec.m. = 1113 keV (Ex = 3544.3 keV) has also been remeasured and its strength has been found to be in good agreement with previous measurements. Conclusions: An extrapolation of the S factor of 20Ne(p ,γ )21Na has been made to low energies using the R -matrix fit. The reaction rate from the subthreshold resonance was

  11. 21 CFR 701.20 - Detergent substances, other than soap, intended for use in cleansing the body.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 7 2013-04-01 2013-04-01 false Detergent substances, other than soap, intended... Ingredients § 701.20 Detergent substances, other than soap, intended for use in cleansing the body. (a) In its definition of the term cosmetic, the Federal Food, Drug, and Cosmetic Act specifically excludes soap. The...

  12. 21 CFR 701.20 - Detergent substances, other than soap, intended for use in cleansing the body.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 7 2012-04-01 2012-04-01 false Detergent substances, other than soap, intended... Ingredients § 701.20 Detergent substances, other than soap, intended for use in cleansing the body. (a) In its definition of the term cosmetic, the Federal Food, Drug, and Cosmetic Act specifically excludes soap. The...

  13. 21 CFR 701.20 - Detergent substances, other than soap, intended for use in cleansing the body.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 7 2014-04-01 2014-04-01 false Detergent substances, other than soap, intended... Ingredients § 701.20 Detergent substances, other than soap, intended for use in cleansing the body. (a) In its definition of the term cosmetic, the Federal Food, Drug, and Cosmetic Act specifically excludes soap. The...

  14. Past and current weight change and forearm bone loss in middle-aged women: the Nord-Trøndelag Health Study, Norway.

    PubMed

    Forsmo, Siri; Langhammer, Arnulf; Schei, Berit

    2009-01-01

    The aim of this study was to investigate the association between bone loss and weight change before and concurrently to the assessment of forearm bone loss over 4.6 years in a population-based cohort of middle-aged women followed for more than 15 years. Among 8,856 women aged 45 to 60 years attending the first Nord-Trøndelag Health Study study, Norway (1984-1986), a 35% random sample was invited for forearm densitometry at Nord-Trøndelag Health Study 2 (1995-1997), and 2,188 women (78%) attended. After an average period of 4.6 years, they were subsequently invited for follow-up densitometry in 2001, and 1,421 women (67.8%) met. Weight and height were measured on all three occasions. During the total period of observation since baseline (15.5 y), the mean weight had increased by 3.4 kg, mostly in the youngest women. Weight loss had an accelerating and weight gain a decelerating effect on bone loss, and this was observed both for weight change occurring before the bone mineral density follow-up and for concurrent weight change. The relationship between prior weight gain or loss and bone loss seemed to persist, independent of the weight change observed during the period of bone loss assessment. Despite no mechanical impact of body weight on the forearm, weight loss in midlife women seems to be associated with a long-lasting negative effect on bone and vice versa for weight gain. This is presumably explained by humoral factors.

  15. The relationship between headache and religious attendance (the Nord-Trøndelag health study- HUNT)

    PubMed Central

    2014-01-01

    Background Religious belief can be used as a pain coping strategy. Our purpose was to evaluate the relationship between headache and religious activity using prospective data from a large population-based study. Methods This longitudinal cohort study used data from two consecutive surveys in the Nord-Trøndelag Health Survey (HUNT 2 and 3) performed in 1995–1997; and 2006–2008. Among the 51,383 participants aged ≥ 20 years who answered headache questions at baseline, 41,766 were eligible approximately 11 years later. Of these, 25,177 (60%) completed the question in HUNT 3 regarding religious activity. Frequent religious attendees (fRA) (used as a marker of stronger religious belief than average) were defined as those who had been to church/prayer house at least once monthly during the last six months. Results In the multivariate analyses, adjusting for known potential confounders, individuals with headache 1–14 days/month in HUNT 2 were more likely to be fRA 11 years later than headache-free individuals. Migraine at baseline predisposed more strongly to fRA at follow-up (OR = 1.25; 95% CI 1.19-1.40) than did non-migrainous headache (OR = 1.13; 95% 1.04-1.23). The odds of being fRA was 48% increased (OR 1.48; 95% 1.19-1.83) among those with migraine 7–14 days/month at baseline compared to subjects without headache. In contrast, headache status at baseline did not influence the odds of being frequent visitors of concerts, cinema and/or theatre at follow-up 11 years later. Conclusions In this prospective study, headache, in particular migraine, at baseline slightly increased the odds of being fRA 11 years later. PMID:24386923

  16. 21 CFR 106.20 - Ingredient control.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... CONSUMPTION INFANT FORMULA QUALITY CONTROL PROCEDURES Quality Control Procedures for Assuring Nutrient Content of Infant Formulas § 106.20 Ingredient control. (a) Except as provided in § 106.20(b), no analysis... prepared by the infant formula manufacturer shall be sampled and analyzed for each relied-upon nutrient...

  17. Surveys of microfungi in a former industrial area in Duisburg-Nord.

    PubMed

    Feige, G B; Ale-Agha, N; Dachowski, M; Kricke, R

    2002-01-01

    One hundred and forty microfungi (Ascomycetes and Deuteromycetes) were collected in the "Landschaftspark Duisburg-Nord" located in North Rhine-Westphalia. New hosts for rarely found fungi are recorded for the first time. New for Germany are Massaria inquinans (Tode) De Not. and Nitschkia grevillei (Rhem) Nannf. on Acer pseudoplatanus L., Pirottaea nigrostriata Graddon on Artemisia vulgaris L., Ceratopycnis clematidis Höhn. on Clematis vitalba L., Dasyscyphus aff. humuli (W. Phillips) Dennis on Humulus lupulus L. and Leptosphaeria derasa (Berk. & Br.) Auersw. on Senecio inaequidens DC. New for North Rhine-Westphalia are Chaetosphaerella phaeostroma (Durieu & Mont.) E. Müller & Booth and Phomopsis platanoides (Cooke) Died. on Acer pseudoplatanus L., Microsphaeropsis pseudaspera Sutton, Mycosphaerella osborniae D. Hawksw. & Sivan. and Phomopsis oblita Sacc. on Artemisia vulgaris L., Leptosphaeria acuta (Fr.) P. Karst. and Leptosphaeria doliolum (Pers.) Ces. & De Not. on Bryonia dioica Jacq., Ophiobolus erythrosporus (Riess) G. Winter and Pleospora herbarum (Pers.) Rabenh. ex Ces. & De Not. on Dipsacus sylvestris (Huds), Keissleriella ocellata (Niessl) Bose on Hypericum perforatum L., Dactylaria aff. graminicola on Lolium perenne L., Siroplacodium aff. atrum on Oenothera beinnis L., Diatrypella favacea (Fr.) Sacc. on Prunus spec., Hapalosphaeria deformans (Syd.) Syd. and Microdiscula rubicola (Bres.) Höhn. on Rubus fructicosus agg. L., Cryptodiaporthe salicina (Pers.) Wehm. on Salix alba L. and Pleurophoma pleurospora (Sacc.) Höhn. on Salix caprea L.

  18. Self-rated health and mortality in different occupational classes and income groups in Nord-Trøndelag County, Norway.

    PubMed

    Holseter, Christoffer; Dalen, Joakim Døving; Krokstad, Steinar; Eikemo, Terje Andreas

    2015-03-10

    People with a lower socioeconomic position have a higher the prevalence of most self-rated health problems. In this article we ask whether this may be attributed to self-rated health not reflecting actual health, understood as mortality, in different socioeconomic groups. For the study we used data from the Nord-Trøndelag Health Study 1984-86 (HUNT1), in which the county's entire adult population aged 20 years and above were invited to participate. The association between self-rated health and mortality in different occupational classes and income groups was analysed. The analysis corrected for age, chronic disease, functional impairment and lifestyle factors. The association between self-rated health and mortality was of the same order of magnitude for the occupational classes and income groups, but persons without work/income and with poor self-rated health stood out. Compared with persons in the highest socioeconomic class, unemployed men had a hazard ratio for death that was three times higher in the follow-up period. For women with no income, the ratio was twice as high. INTERPRETATION Self-rated health and mortality largely conform to the different socioeconomic strata. This supports the perception that socioeconomic differences in health are a reality and represent a significant challenge nationally. Our results also increase the credibility of findings from other studies that use self-reported health in surveys to measure differences and identify the mechanisms that create them.

  19. Absorbing Aerosols Workshop, January 20-21, 2016

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nasiri, Shaima; Williamson, Ashley; Cappa, Christopher D.

    2016-07-01

    A workshop was held at DOE Headquarters on January 20-21, 2016 during which experts within and outside DOE were brought together to identify knowledge gaps in modeling and measurement of the contribution of absorbing aerosols (AA) to radiative forcing. Absorbing aerosols refer to those aerosols that absorb light, whereby they both reduce the amount of sunlight reaching the surface (direct effect) and heat their surroundings. By doing so, they modify the vertical distribution of heat in the atmosphere and affect atmospheric thermodynamics and stability, possibly hastening cloud drop evaporation, and thereby affecting cloud amount, formation, dissipation and, ultimately, precipitation. Depositionmore » of AA on snow and ice reduces surface albedo leading to accelerated melt. The most abundant AA type is black carbon (BC), which results from combustion of fossil fuel and biofuel. The other key AA types are brown carbon (BrC), which also results from combustion of fossil fuel and biofuel, and dust (crustal material). Each of these sources may result from, and be strongly influenced by, anthropogenic activities. The properties and amounts of AA depend upon various factors, primarily fuel source and burn conditions (e.g., internal combustion engine, flaming or smoldering wildfire), vegetation type (in the case of BC and BrC), and in the case of dust, soil type and ground cover (i.e., vegetation, snow, etc.). After emission, AA undergo chemical processing in the atmosphere that affects their physical and chemical properties. Thus, attribution of sources of AA, and understanding processes AA undergo during their atmospheric lifetimes, are necessary to understand how they will behave in a changing climate.« less

  20. 20 CFR 411.551 - How are EN payments calculated for transition cases pending on July 21, 2008?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false How are EN payments calculated for transition cases pending on July 21, 2008? 411.551 Section 411.551 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Network Payment Systems § 411.551 How...

  1. 20 CFR 411.551 - How are EN payments calculated for transition cases pending on July 21, 2008?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false How are EN payments calculated for transition cases pending on July 21, 2008? 411.551 Section 411.551 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Network Payment Systems § 411.551 How...

  2. 20 CFR 411.551 - How are EN payments calculated for transition cases pending on July 21, 2008?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false How are EN payments calculated for transition cases pending on July 21, 2008? 411.551 Section 411.551 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Network Payment Systems § 411.551 How...

  3. 20 CFR 411.551 - How are EN payments calculated for transition cases pending on July 21, 2008?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false How are EN payments calculated for transition cases pending on July 21, 2008? 411.551 Section 411.551 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Network Payment Systems § 411.551 How...

  4. 20 CFR 411.551 - How are EN payments calculated for transition cases pending on July 21, 2008?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false How are EN payments calculated for transition cases pending on July 21, 2008? 411.551 Section 411.551 Employees' Benefits SOCIAL SECURITY ADMINISTRATION THE TICKET TO WORK AND SELF-SUFFICIENCY PROGRAM Employment Network Payment Systems § 411.551 How...

  5. [Sources of information on suicide attempts in the Nord - Pas-de-Calais (France). Contributions and limitations].

    PubMed

    Plancke, L; Ducrocq, F; Clément, G; Chaud, P; Haeghebaert, S; Amariei, A; Chan-Chee, C; Goldstein, P; Vaiva, G

    2014-12-01

    There are very few permanent indicators of mental health in France; suicidal behavior is often only understood on the basis of deaths by suicide. The epidemiological interest and methodological limits of four medico-administrative databases from which data on suicide attempts can be extracted have been the subject of a study in the Nord - Pas-de-Calais Region of France: telephone calls for emergency medical assistance after suicide attempt (2009 to 2011), admissions in emergency services with a diagnosis of suicide attempt (2012), medical-surgical hospital admissions as a result of suicide attempt (2009 to 2011), and psychiatric admissions with a diagnosis of suicide attempt (2011). Usable data were provided by one of two emergency medical assistance units, five of thirty emergency departments and all medical-surgical and psychiatric units; in data from the latter two sources, a unique anonymous identifier gave individual statistics, while the first two covered only suicide attempts. In 2011, the number of suicide attempt calls per 100,000 inhabitants was 304, whereas the number of hospitalisations with this diagnosis was 275; rates are highest in men between 20 and 49 years of age, and in women below 20 years of age and between 40 and 49. Sources are seen to be very homogeneous with regards to the average age at which suicide took place (between 37.8 and 38.5 years, depending on the source), and to the sex (55.0% to 57.6% of women). In 2011, the number of patients with a diagnosis of suicide attempt treated in psychiatry is 2.6 times lower than the number hospitalised for suicide attempt in medical-surgical units (3563 vs 9327). Permanent gathering of data, and the large volume of data recorded, should encourage the use of these databases in the definition and assessment of mental health policy: an increased contribution from emergency call centers and emergency services, and the coding of the suicidal nature of intoxications by a few clearly under-declaring units

  6. 21 CFR 225.20 - Buildings.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... CURRENT GOOD MANUFACTURING PRACTICE FOR MEDICATED FEEDS Construction and Maintenance of Facilities and Equipment § 225.20 Buildings. (a) The location, design, construction, and physical size of the buildings and other production facilities are factors important to the manufacture of medicated feed. The features of...

  7. Telecourses: 20 Myths, 21 Realities.

    ERIC Educational Resources Information Center

    Luskin, Bernard J.

    1983-01-01

    Refutes 20 myths about telecourses, e.g., telecourses require only television viewing, they are easy, they will replace classroom teachers and all courses on campus, they dehumanize learning, and they do not undergo a rigorous curriculum process, and are too expensive to produce and offer. (DMM)

  8. A bronze matryoshka: the discrete intermetalloid cluster [Sn@Cu12@Sn20](12-) in the ternary phases A12Cu12Sn21 (A = Na, K).

    PubMed

    Stegmaier, Saskia; Fässler, Thomas F

    2011-12-14

    The synthesis and crystal structure of the first ternary A-Cu-Sn intermetallic phases for the heavier alkali metals A = Na to Cs is reported. The title compounds A(12)Cu(12)Sn(21) show discrete 33-atom intermetalloid Cu-Sn clusters {Sn@Cu(12)@Sn(20)}, which are composed of {Sn(20)} pentagonal dodecahedra surrounding {Cu(12)} icosahedra with single Sn atoms at the center. Na(12)Cu(12)Sn(21) and K(12)Cu(12)Sn(21) were characterized by single-crystal XRD studies, and the successful synthesis of analogous A-Cu-Sn compounds with A = Rb and Cs is deduced from powder XRD data. The isotypic A(12)Cu(12)Sn(21) phases crystallize in the cubic space group Pn ̅3m (No. 224), with the Cu-Sn clusters adopting a face centered cubic arrangement. A formal charge of 12- can be assigned to the {Sn@Cu(12)@Sn(20)} cluster unit, and the interpretation of the title compounds as salt-like intermetallic phases featuring discrete anionic intermetalloid [Sn@Cu(12)@Sn(20)](12-) clusters separated by alkali metal cations is supported by electronic structure calculations. For both Na(12)Cu(12)Sn(21) and K(12)Cu(12)Sn(21), DFT band structure calculations (TB-LMTO-ASA) reveal a band gap. The discrete [Sn@Cu(12)@Sn(20)](12-) cluster is analyzed in consideration of the molecular orbitals obtained from hybrid DFT calculations (Gaussian 09) for the cluster anion. The [Sn@Cu(12)@Sn(20)](12-) cluster MOs can be classified with labels indicating the numbers of radial and angular nodes, in the style of spherical shell models of cluster bonding. © 2011 American Chemical Society

  9. Spectroscopic study of the radionuclide 21Na for the astrophysical 17F(α ,p )20Ne reaction rate

    NASA Astrophysics Data System (ADS)

    Cha, S. M.; Chae, K. Y.; Ahn, S.; Bardayan, D. W.; Chipps, K. A.; Cizewski, J. A.; Howard, M. E.; Kozub, R. L.; Kwak, K.; Manning, B.; Matos, M.; O'Malley, P. D.; Pain, S. D.; Peters, W. A.; Pittman, S. T.; Ratkiewicz, A.; Smith, M. S.; Strauss, S.

    2017-08-01

    The 24Mg(p ,α )21Na reaction was measured at the Holifield Radioactive Ion Beam Facility of the Oak Ridge National Laboratory to study the spectroscopy of the radionuclide 21Na. A 31-MeV proton beam from the 25 MV tandem accelerator bombarded isotopically enriched 24Mg targets. Recoiling 4He particles were identified by an annular silicon strip detector array. Two energy levels at Ex=6.594 and 7.132 MeV were observed for the first time. By comparing the experimentally obtained angular distributions and distorted wave Born approximation calculations, the spins and parities of 21Na energy levels were constrained. The astrophysically-important 17F(α ,p )20Ne reaction rate was also calculated for the first time using resonance parameters for 12 energy levels.

  10. 21 CFR 20.20 - Policy on disclosure of Food and Drug Administration records.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Administration records. 20.20 Section 20.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND... the record will be so used, may be requested when: (1) The requested record is contained in a Privacy... Administration records. (a) The Food and Drug Administration will make the fullest possible disclosure of records...

  11. 21 CFR 349.20 - Eyewashes.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE OPHTHALMIC DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 349.20 Eyewashes. The active... isotonicity with tears, suitable agents for establishing pH and buffering to achieve the same pH as tears, and...

  12. 21 CFR 349.20 - Eyewashes.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS FOR HUMAN USE OPHTHALMIC DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 349.20 Eyewashes. The active... isotonicity with tears, suitable agents for establishing pH and buffering to achieve the same pH as tears, and...

  13. Biocatalytic synthesis of 4-pregnen-20,21-diol-3-one, a selective inhibitor of human 5alpha-reductase type II.

    PubMed

    Hannemann, Frank; Bernhardt, Rita; Jose, Joachim

    2007-10-01

    Biocatalysis, the conversion of substrates into valuable products by the use of enzymes, has some striking advantages in comparison to standard organic chemistry for drug synthesis. By biocatalysis, substrates that contain several identical reactive groups at different positions can be converted with high regio-selectivity and enantio-selectivity. In this study, an E. coli isolate (E132) was identified which was able to convert the steroid desoxycorticosterone into the product 4-pregnen-20,21-diol-3-one in real terms. The product was purified from the cell culture supernatant by HPLC and its structure was demonstrated by mass spectrometry and NMR spectroscopy. It was tested on inhibition of human 5alpha-reductases type I and type II. At a concentration of 10 microM, inhibition was 49.0% for type I and 81.8% for type II, whereas there was no inhibition of human aromatase (CYP19) at 20 microM and human 17alpha-hydroxylase-C17,20-lyase (CYP17) at 2.5 microM detectable. The IC50 value of 4-pregnen-20,21-diol-3-one for human 5alpha-reductase type II was determined to be 1.56 microM.

  14. Functional Conservation and Divergence among Homoeologs of TaSPL20 and TaSPL21, Two SBP-Box Genes Governing Yield-Related Traits in Hexaploid Wheat1[OPEN

    PubMed Central

    Mao, Xinguo; Li, Ang; Wang, Jingyi; Chang, Xiaoping; Zhang, Xueyong

    2017-01-01

    Maintaining high and stable yields has become an increasing challenge in wheat breeding due to climate change. Although Squamosa-promoter binding protein (SBP)-box genes have important roles in plant development, very little is known about the actual biological functions of wheat SBP-box family members. Here, we dissect the functional conservation, divergence, and exploitation of homoeologs of two paralogous TaSPL wheat loci during domestication and breeding. TaSPL20 and TaSPL21 were highly expressed in the lemma and palea. Ectopic expressions of TaSPL20/21 in rice exhibited similar functions in terms of promoting panicle branching but had different functions during seed development. We characterized all six TaSPL20/21 genes located across the three homoeologous (A, B, and D) genomes. According to the functional analysis of naturally occurring variants in 20 environments, four favorable haplotypes were identified. Together, they reduced plant height by up to 27.5%, and TaSPL21-6D-HapII increased 1000-grain weight by 9.73%. Our study suggests that TaSPL20 and TaSPL21 homoeologs underwent diversification in function with each evolving its own distinctive characteristics. During domestication and breeding of wheat in China, favorable haplotypes of each set were selected and exploited to varying degrees due to their large effects on plant height and 1000-grain weight. PMID:28424214

  15. The Effect of Sequential Dependence on the Sampling Distributions of KR-20, KR-21, and Split-Halves Reliabilities.

    ERIC Educational Resources Information Center

    Sullins, Walter L.

    Five-hundred dichotomously scored response patterns were generated with sequentially independent (SI) items and 500 with dependent (SD) items for each of thirty-six combinations of sampling parameters (i.e., three test lengths, three sample sizes, and four item difficulty distributions). KR-20, KR-21, and Split-Half (S-H) reliabilities were…

  16. Suppression of ovarian activity with a low-dose 21/7-day regimen oral contraceptive containing ethinylestradiol 20 mcg/drospirenone 3 mg in Japanese and Caucasian women.

    PubMed

    Anzai, Yuzuru; Heger-Mahn, Doris; Schellschmidt, Ilka; Marr, Joachim

    2012-07-01

    Two studies assessed the effect of a low-estrogen-dose 21/7-day oral contraceptive containing ethinylestradiol and drospirenone (EE 20 mcg/drsp 3 mg) on ovarian activity in Japanese and Caucasian women. Study 1 was conducted in Japanese women (20-35 years), and Study 2 was conducted in Caucasian women (18-35 years). All women received EE 20 mcg/drsp 3 mg in a 21-day active pill regimen. The primary endpoint was the proportion of women with ovulation inhibition (Hoogland score <6; as assessed by transvaginal ultrasonography) during treatment cycle 2. Japanese (n=23) and Caucasian (n=30) women received two cycles of study treatment. During treatment cycle 2, ovulation was inhibited in 100% and 92.9% of Japanese and Caucasian women, respectively. EE 20 mcg/drsp 3 mg in a 21/7-day regimen provides comparable ovarian suppression in Japanese and Caucasian women, with normal ovarian function resuming shortly after treatment end in both populations. Copyright © 2012 Elsevier Inc. All rights reserved.

  17. The Opinions of Music Education Students about 20th and 21st Centuries Classical Music: Uludag University Exemplification

    ERIC Educational Resources Information Center

    Sakin, Ajda Senol

    2016-01-01

    The debates of music historians, composers, and performers on difficulties in understanding the 20th and 21st Centuries international classical music and the reasons have been ongoing for years. The opinions of music education students on this matter and their interests in music of these periods are a matter of curiosity. With this research,…

  18. The Pathology of Chronic Obstructive Pulmonary Disease: Progress in the 20th and 21st Centuries.

    PubMed

    Berg, Kyra; Wright, Joanne L

    2016-12-01

    Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and is the fourth leading cause of death worldwide. There has been significant progress in the pathologic description and pathophysiologic analysis of COPD in the 20th and 21st centuries. We review the history, progression, and significance of pathologic alterations in COPD, including emphysematous changes, airway alterations, and vascular alterations. We also indicate what pathologic features of COPD the practicing pathologist should be describing in standard surgical and autopsy specimens.

  19. Synthesis and characterization of metastable, 20 nm-sized Pna21-LiCoPO4 nanospheres

    NASA Astrophysics Data System (ADS)

    Ludwig, Jennifer; Nordlund, Dennis; Doeff, Marca M.; Nilges, Tom

    2017-04-01

    The majority of research activities on LiCoPO4 are focused on the phospho-olivine (space group Pnma), which is a promising high-voltage cathode material for Li-ion batteries. In contrast, comparably little is known about its metastable Pna21 modification. Herein, we present a comprehensive study on the structure-property relationships of 15-20 nm Pna21-LiCoPO4 nanospheres prepared by a simple microwave-assisted solvothermal process. Unlike previous reports, the results indicate that the compound is non-stoichiometric and shows cation-mixing with Co ions on the Li sites, which provides an explanation for the poor electrochemical performance. Co L2,3-edge X-ray absorption spectroscopic data confirm the local tetrahedral symmetry of Co2+. Comprehensive studies on the thermal stability using thermogravimetric analysis, differential scanning calorimetry, and in situ powder X-ray diffraction show an exothermic phase transition to olivine Pnma-LiCoPO4 at 527 °C. The influence of the atmosphere and the particle size on the thermal stability is also investigated.

  20. 21 CFR 1230.20 - General guaranty.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... CAUSTIC POISON ACT Guaranty § 1230.20 General guaranty. In lieu of a particular guaranty for each lot of... to _____ are not misbranded within the meaning of the Federal Caustic Poison Act. (Date) (Signature... Poison Act. (Date) (Signature and address of manufacturer or wholesaler) ...

  1. 21 CFR 1230.20 - General guaranty.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... CAUSTIC POISON ACT Guaranty § 1230.20 General guaranty. In lieu of a particular guaranty for each lot of... to _____ are not misbranded within the meaning of the Federal Caustic Poison Act. (Date) (Signature... Poison Act. (Date) (Signature and address of manufacturer or wholesaler) ...

  2. 21 CFR 1230.20 - General guaranty.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... CAUSTIC POISON ACT Guaranty § 1230.20 General guaranty. In lieu of a particular guaranty for each lot of... to _____ are not misbranded within the meaning of the Federal Caustic Poison Act. (Date) (Signature... Poison Act. (Date) (Signature and address of manufacturer or wholesaler) ...

  3. 21 CFR 1230.20 - General guaranty.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... CAUSTIC POISON ACT Guaranty § 1230.20 General guaranty. In lieu of a particular guaranty for each lot of... to _____ are not misbranded within the meaning of the Federal Caustic Poison Act. (Date) (Signature... Poison Act. (Date) (Signature and address of manufacturer or wholesaler) ...

  4. 21 CFR 1230.20 - General guaranty.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... CAUSTIC POISON ACT Guaranty § 1230.20 General guaranty. In lieu of a particular guaranty for each lot of... to _____ are not misbranded within the meaning of the Federal Caustic Poison Act. (Date) (Signature... Poison Act. (Date) (Signature and address of manufacturer or wholesaler) ...

  5. 21 CFR 20.105 - Testing and research conducted by or with funds provided by the Food and Drug Administration.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Testing and research conducted by or with funds... Categories of Records § 20.105 Testing and research conducted by or with funds provided by the Food and Drug Administration. (a) Any list that may be prepared by the Food and Drug Administration of testing and research...

  6. 21 CFR 20.105 - Testing and research conducted by or with funds provided by the Food and Drug Administration.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Testing and research conducted by or with funds... Categories of Records § 20.105 Testing and research conducted by or with funds provided by the Food and Drug Administration. (a) Any list that may be prepared by the Food and Drug Administration of testing and research...

  7. 21 CFR 130.20 - Food additives proposed for use in foods for which definitions and standards of identity are...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Food additives proposed for use in foods for which...: GENERAL Food Additives in Standardized Foods § 130.20 Food additives proposed for use in foods for which... the act, which proposes the inclusion of a food additive in such definition and standard of identity...

  8. 21 CFR 130.20 - Food additives proposed for use in foods for which definitions and standards of identity are...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Food additives proposed for use in foods for which...: GENERAL Food Additives in Standardized Foods § 130.20 Food additives proposed for use in foods for which... the act, which proposes the inclusion of a food additive in such definition and standard of identity...

  9. 21 CFR 130.20 - Food additives proposed for use in foods for which definitions and standards of identity are...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Food additives proposed for use in foods for which...: GENERAL Food Additives in Standardized Foods § 130.20 Food additives proposed for use in foods for which... the act, which proposes the inclusion of a food additive in such definition and standard of identity...

  10. 21 CFR 130.20 - Food additives proposed for use in foods for which definitions and standards of identity are...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Food additives proposed for use in foods for which...: GENERAL Food Additives in Standardized Foods § 130.20 Food additives proposed for use in foods for which... the act, which proposes the inclusion of a food additive in such definition and standard of identity...

  11. 21 CFR 130.20 - Food additives proposed for use in foods for which definitions and standards of identity are...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Food additives proposed for use in foods for which...: GENERAL Food Additives in Standardized Foods § 130.20 Food additives proposed for use in foods for which... the act, which proposes the inclusion of a food additive in such definition and standard of identity...

  12. Drilling, construction, and aquifer-test data from wells 3-3307-20 and -21, Thompson Corner exploratory wells I and II, Oahu, Hawaii

    USGS Publications Warehouse

    Presley, T.K.; Oki, D.S.

    1996-01-01

    The Thompson Corner exploratory wells I and II (State well numbers 3-3307-20 and -21) were drilled near Thompson Corner, about 2.2 miles south-southwest of the town of Haleiwa. The wells are located on agricultural land in the Waialua ground-water area. The wells are about 50 feet apart and penetrate about 90 feet into the ground water. Aquifer tests were conducted using well 3-3307-20 as a pumping well and well 3-3307-21 as an observation well. Well-construction data, logs of drilling notes, geologic descriptions for the samples, and aquifer-test data are presented for the wells. The wells are two of twelve exploratory wells drilled in the north-central Oahu area between July 1993 and May 1994 in cooperation with the Honolulu Board of Water Supply.

  13. Geomorphic Change Detection and Quantification Using LiDAR, SONAR and RTK-GPS of Sandbars along the Snake River in Hells Canyon

    NASA Astrophysics Data System (ADS)

    Morehead, M. D.; Wilson, T.; Butler, M.; Seal, N.

    2012-12-01

    Sediment depletion downstream of large dams causes long-term geomorphic change along a river reach. Short- and long-term, natural and human-altered discharge patterns cause additional geomorphic change. Annual high-resolution, topobathymetry data are being collected on sandbars to track patterns of geomorphic and volumetric change through time. The sandbars are located along the Hells Canyon reach of the Snake River on the Oregon/Idaho border. The bars are downstream of a number of dams that have cut off the upstream source of sand to the Hells Canyon reach. We are combining LiDAR data for above water areas, multibeam SONAR data for below water areas and RTK-GPS data for the water/land interface and densely vegetated areas. Idaho Power has installed and surveyed a control point network to allow accurate positioning of the data and aligning of the various data sets. Data densities are a few points per square meter with the RTK-GPS, tens of points per square meter with the SONAR, and up to hundreds of points per square meter with the ground-based LiDAR. Automated and manual methods are being used to clean the point cloud data. A number of techniques are being used to convert the point clouds to grids, typically utilizing a unique technique for each data type (GPS, LiDAR, and SONAR). Surface roughness data are being used to determine the edges of the sand region, especially in the underwater area where we do not have visual confirmation of the boundary. After the different data types are gridded, they are combined to create seamless surfaces which are then analyzed. The morphologies of the central crest and the back channel of the sandbars are changing between years. In years with higher than average spring flows, the central crest of the sandbars increases in elevation and the back channels deepen. In years with moderate and low spring flows, the height of the crests decline and the back channels fill in. The flattening of the sandbars is attributed to natural

  14. Funding Proposal for EDISON’20 Conference Buffalo, New York, 07/17 - 07/21, 2017

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bird, Jonathan

    EDISON’20 – The 20th International Conference on Electron Dynamics in Semiconductors, Optoe- lectronics and Nanostructures – was held at the Hyatt Regency Hotel, Buffalo, NY from July 17 – 21, 2017. The technical focus of this conference was on the fundamental physics and applications of nonequilibrium classical and quantum carrier dynamics in semiconductors, optoelectronic de- vices, and nanostructures. This five-day, single-session conference featured a program consisting of some 15 invited talks, given by internationally-renowned academics from the U.S., Europe, and Japan. Their keynote presentations covered topics including: terahertz phenomena in semiconductors; quantum transport in novel two-dimensional semiconductors; topological insulators; mesoscopicmore » phenomena in semiconductors, and; semiconductor spintronics. The invited papers were supplemented by some 30 contributed talks, selected from almost 120 abstracts submitted in response to the conference’s call for papers, and by two poster sessions that each consisted of close to 40 different reports. This critical mass in terms of scientific content ensured a highly vibrant conference, in which leaders in the field had the opportunity to interact closely with early-career scientists.« less

  15. Cycle control and bleeding pattern of a 24/4 regimen of drospirenone 3 mg/ethinylestradiol 20 μg compared with a 21/7 regimen of desogestrel 150 μg/ethinylestradiol 20 μg: a pooled analysis.

    PubMed

    Anttila, Leena; Neunteufel, Walter; Petraglia, Felice; Marr, Joachim; Kunz, Michael

    2011-01-01

    The degree of cycle control achieved with a hormonal contraceptive method is an important determinant of its acceptance and continuation. This study set out to compare the cycle control and bleeding profile of drospirenone (DRSP) 3 mg/ethinylestradiol (EE) 20 μg in a 24-active pill/4-inert pill (24/4) regimen (YAZ®) with those of desogestrel (DSG) 150 μg/EE 20 μg in a 21/7 regimen (Mercilon®), an established European combined oral contraceptive (COC). Bleeding data from women aged 17-36 years who received either DRSP 3 mg/EE 20 μg in a 24/4 regimen (n = 1285) or DSG 150 μg/EE 20 μg in a 21/7 regimen (n = 471) during four clinical studies were pooled and analysed over seven treatment cycles. The maximum intensity of scheduled withdrawal bleeding was 'normal bleeding' for >50% of subjects in cycles 1-6 in both treatment groups. Moreover, the incidence of unscheduled intracyclic bleeding during cycles 2-7 was comparable between treatment types (10.2-14.9% in women treated with DRSP 3 mg/EE 20 μg 24/4 vs 8.6-13.8% in women treated with DSG 150 μg/EE 20 μg 21/7). Overall, similar bleeding patterns were observed with both treatments. DRSP 3 mg/EE 20 μg 24/4 is associated with a bleeding profile and cycle control that is comparable to that of an established, low-dose COC formulation.

  16. The insertion of the non-heme FeB cofactor into nitric oxide reductase from P. denitrificans depends on NorQ and NorD accessory proteins.

    PubMed

    Kahle, Maximilian; Ter Beek, Josy; Hosler, Jonathan P; Ädelroth, Pia

    2018-06-03

    Bacterial NO reductases (NOR) catalyze the reduction of NO into N 2 O, either as a step in denitrification or as a detoxification mechanism. cNOR from Paracoccus (P.) denitrificans is expressed from the norCBQDEF operon, but only the NorB and NorC proteins are found in the purified NOR complex. Here, we established a new purification method for the P. denitrificans cNOR via a His-tag using heterologous expression in E. coli. The His-tagged enzyme is both structurally and functionally very similar to non-tagged cNOR. We were also able to express and purify cNOR from the structural genes norCB only, in absence of the accessory genes norQDEF. The produced protein is a stable NorCB complex containing all hemes and it can bind gaseous ligands (CO) to heme b 3 , but it is catalytically inactive. We show that this deficient cNOR lacks the non-heme iron cofactor Fe B . Mutational analysis of the nor gene cluster revealed that it is the norQ and norD genes that are essential to form functional cNOR. NorQ belongs to the family of MoxR P-loop AAA+ ATPases, which are in general considered to facilitate enzyme activation processes often involving metal insertion. Our data indicates that NorQ and NorD work together in order to facilitate non-heme Fe insertion. This is noteworthy since in many cases Fe cofactor binding occurs spontaneously. We further suggest a model for NorQ/D-facilitated metal insertion into cNOR. Copyright © 2018 Elsevier B.V. All rights reserved.

  17. Proceedings of the Very Low Frequency (VLF) Ambient Noise Workshop Held in Stennis, Mississippi on 20-21 September 1988

    DTIC Science & Technology

    1988-12-01

    20-21 September 1988 (This document contains the unclassified presentations only.) DTIC Ronad A by&S"LECTE 0 iCompiled W.y: Ronald A. Wagstaff 0140...7 IV* Summary........................11 V. Presentations ................................... 37 "Opening Remarks," R. Wagstaff ............... 39...34Influence of Noise Source Distributions and Propagation Mechanisms on Noise Field Directionality," M. Bradley/R. Wagstaff ...... 51 "Distant Storm

  18. 21 CFR 20.41 - Time limitations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... shall begin as of the time at which a request for records is logged in by the Freedom of Information... is redirected to the Freedom of Information Staff and is logged in there in accordance with § 20.40(c... for records is logged in at the Freedom of Information Staff, the agency shall send a letter to the...

  19. Hells Canyon to the Bitterroot front: A transect from the accretionary margin eastward across the Idaho batholith

    USGS Publications Warehouse

    Lewis, Reed S.; Smith, Keegan L.; Gaschnig, Richard M.; LaMaskin, Todd A.; Lund, Karen; Gray, Keith D.; Tikoff, Basil; Stetson-Lee, Tor; Moore, Nicholas

    2014-01-01

    This field guide covers geology across north-central Idaho from the Snake River in the west across the Bitterroot Mountains to the east to near Missoula, Montana. The regional geology includes a much-modified Mesozoic accretionary boundary along the western side of Idaho across which allochthonous Permian to Cretaceous arc complexes of the Blue Mountains province to the west are juxtaposed against autochthonous Mesoproterozoic and Neoproterozoic North American metasedimentary assemblages intruded by Cretaceous and Paleogene plutons to the east. The accretionary boundary turns sharply near Orofino, Idaho, from north-trending in the south to west-trending, forming the Syringa embayment, then disappears westward under Miocene cover rocks of the Columbia River Basalt Group. The Coolwater culmination east of the Syringa embayment exposes allochthonous rocks well east of an ideal steep suture. North and east of it is the Bitterroot lobe of the Idaho batholith, which intruded Precambrian continental crust in the Cretaceous and Paleocene to form one of the classical North American Cordilleran batholiths. Eocene Challis plutons, products of the Tertiary western U.S. ignimbrite flare-up, intrude those batholith rocks. This guide describes the geology in three separate road logs: (1) The Wallowa terrane of the Blue Mountains province from White Bird, Idaho, west into Hells Canyon and faults that complicate the story; (2) the Mesozoic accretionary boundary from White Bird to the South Fork Clearwater River east of Grangeville and then north to Kooskia, Idaho; and (3) the bend in the accretionary boundary, the Coolwater culmination, and the Bitterroot lobe of the Idaho batholith along Highway 12 east from near Lewiston, Idaho, to Lolo, Montana.

  20. 20 CFR 225.21 - Survivor Tier I PIA.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... INSURANCE AMOUNT DETERMINATIONS PIA's Used in Computing Survivor Annuities and the Amount of the Residual Lump-Sum Payable § 225.21 Survivor Tier I PIA. The Survivor Tier I PIA is used in computing the tier I... Security Act using the deceased employee's combined railroad and social security earnings after 1950 (or...

  1. Timing of metamorphism and exhumation in the Nordøyane ultra-high-pressure domain, Western Gneiss Region, Norway: New constraints from complementary CA-ID-TIMS and LA-MC-ICP-MS geochronology

    NASA Astrophysics Data System (ADS)

    Butler, J. P.; Jamieson, R. A.; Dunning, G. R.; Pecha, M. E.; Robinson, P.; Steenkamp, H. M.

    2018-06-01

    We present the results of a combined CA-ID-TIMS and LA-MC-ICP-MS U-Pb geochronology study of zircon and associated rutile and titanite from the Nordøyane ultra-high-pressure (UHP) domain in the Western Gneiss Region (WGR) of Norway. The dated samples include 4 eclogite bodies, 2 host-rock migmatites, and 2 cross-cutting pegmatites and leucosomes, all from the island of Harøya. Zircon from a coesite eclogite yielded an age of ca. 413 Ma, interpreted as the time of UHP metamorphism in this sample. Zircon data from the other eclogite bodies yielded metamorphic ages of ca. 413 Ma, 407 Ma, and 406 Ma; zircon trace-element data associated with 413 Ma and 407 Ma ages are consistent with eclogite-facies crystallization. In all of the eclogites, U-Pb dates from zircon cores, interpreted as the times of protolith crystallization, range from ca. 1680-1586 Ma, consistent with Gothian ages from orthogneisses in Nordøyane and elsewhere in the WGR. A zircon core age of ca. 943 Ma from one sample agrees with Sveconorwegian ages of felsic gneisses and pegmatites in the western part of the area. Migmatites hosting the eclogite bodies yielded zircon core ages of ca. 1657-1591 Ma and rim ages of ca. 395-392 Ma, interpreted as the times of Gothian protolith formation and Scandian partial melt crystallization, respectively. Pegmatite in an eclogite boudin neck yielded a crystallization age of ca. 388 Ma, interpreted as the time of melt crystallization. Rutile and titanite from 3 samples (an eclogite and two migmatites) yielded concordant ID-TIMS ages of 378-376 Ma. The results are similar to existing U-Pb data from other Nordøyane eclogites (415-405 Ma). In combination with previous pressure-temperature data from the coesite eclogite, these ages indicate that peak metamorphic conditions of 3 GPa/760 °C were reached ca. 413 Ma, followed by decompression to 1 GPa/810 °C by ca. 397 Ma and cooling below ca. 600 °C by ca. 375 Ma. The results are compatible with protracted UHP

  2. 21 CFR 20.113 - Voluntary product defect reports.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... deletion of data and information falling within the exemptions established in § 20.61 for trade secrets and confidential commercial or financial information and in § 20.63 for personal privacy. (b) If the report is... would identify the person submitting the report and any data or information falling within the exemption...

  3. 21 CFR 20.113 - Voluntary product defect reports.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... deletion of data and information falling within the exemptions established in § 20.61 for trade secrets and confidential commercial or financial information and in § 20.63 for personal privacy. (b) If the report is... would identify the person submitting the report and any data or information falling within the exemption...

  4. Forensic parameters and admixture in Mestizos from five geographic regions of Mexico based on 20 autosomal STRs (Powerplex 21 system).

    PubMed

    Aguilar-Velázquez, J A; Martínez-Cortés, G; Inclán-Sánchez, A; Favela-Mendoza, A F; Velarde-Félix, J S; Rangel-Villalobos, H

    2018-03-01

    We analyzed Mestizo (admixed) population samples from different geographic regions of Mexico (n = 1283) with 20 autosomal STRs (PowerPlex® 21, Promega Corp.). Allele frequencies and forensic parameters from the Northwest, Northeast, West, Center, and Southeast regions are reported, as well as from the pooled Mexican population sample. The combined PD and PE for this 20 STR system were > 0.9999999999 and > 0.99999996593% in all five population samples, respectively. Analysis of molecular variance (AMOVA) of these Mexican population samples, plus Monterrey (Northeast) and Mexico (Center) Cities, showed low but significant differences among Mexican-Mestizos from the seven populations (Fst = 0.20%; p = 0.0000). Structure analysis showed the highest proportion of Native American ancestry in Mexico City, Center, and Southeast regions, respectively, which was in agreement with the estimated genetic distances represented in a MDS plot and a NJ tree. The best fit of population clusters (K = 4) obtained with the Structure software indicates that Mexican-Mestizos are mainly composed by European, African, and two Native American ancestries. The European and Native American ancestries displayed a contrary gradient, increasing toward the North-West and South-Southeast, respectively. These 20 autosomal STR loci improved the admixture estimation regarding previous studies with the 13 CODIS-STRs, as supported by the higher similarity with previous estimates based on genome-wide SNP. In brief, this study validates the confident use of the PowerPlex® 21 system for human identification purposes in Mestizo populations throughout the Mexican territory.

  5. The geochemistry of the Fox Hills-Basal Hell Creek Aquifer in southwestern North Dakota and northwestern South Dakota

    USGS Publications Warehouse

    Thorstenson, Donald C.; Fisher, Donald W.; Croft, Mack G.

    1979-01-01

    The Late Cretaceous Fox Hills Formation and the basal portion of the overlying Hell Creek Formation constitute an important aquifer in the Fort Union coal region. Throughout most of southwestern North Dakota and northwestern South Dakota the aquifer is at depths ranging from 1000 to 2000 ft, except for exposures along the Cedar Creek anticline. Water flows in the aquifer from southwest to northeast, with flow rates of a few feet per year. The recharge and discharge areas of the aquifer are separated by a north-south trending transition zone in which significant changes in water chemistry occur. Dissolved constituents in the recharge area (the western part of the study area) are Na+ = 18 mmol/l, Cl− = 0.7 mmol/1, SO42− = 2.7 mmol/1, and HCO3− = 13 mmol/l (δ13C = −12‰) with pH = 8.5. Ca2+, Mg2+, and K+ are each less than 0.1 mmol/l, dissolved O2 = 0, and traces of H2S and CH4 are present. Computer modeling and carbon isotope data suggest the following reactions in the recharge area. CO2 derived from lignitic carbon reacts to dissolve carbonate minerals, with cations then being exchanged for Na+ on clay minerals. The high pH in the aquifer is the result of buffering by carbonate-ion exchange equilibria. In the discharge area, pH values have declined to 8.3, Cl− has increased from 0.7 to 5.5 mmol/l, with a parallel increase in Na+ SO42− has essentially disappeared, HCO3− has increased from 13 to 21 mmol/l (δ13C = −9‰), CH4 has attained concentrations greater than 0.5 mmol/l, and small amounts of He are present. Traces of H2S are present, and Ca2+, Mg2+, and K+concentrations remain low throughout the aquifer: These changes can be accounted for by reactions in the aquifer: (1) sulfate reduction to pyrite with lignitic material as the carbon source and (2) continuous buffering of pH by the carbonate-ion exchange equilibria. Chemical and hydrologic data suggest that the increase in NaCl results from upward movement of small volumes

  6. 27 CFR 21.24 - Formula No. 20.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... add: A total of 2.0 gallons of either unleaded gasoline, rubber hydrocarbon solvent, kerosene, or deodorized kerosene; or any combination of these. (b) Authorized use. Restricted to fuel use, comparable to...

  7. 27 CFR 21.24 - Formula No. 20.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... add: A total of 2.0 gallons of either unleaded gasoline, rubber hydrocarbon solvent, kerosene, or deodorized kerosene; or any combination of these. (b) Authorized use. Restricted to fuel use, comparable to...

  8. 27 CFR 21.24 - Formula No. 20.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... add: A total of 2.0 gallons of either unleaded gasoline, rubber hydrocarbon solvent, kerosene, or deodorized kerosene; or any combination of these. (b) Authorized use. Restricted to fuel use, comparable to...

  9. 27 CFR 21.24 - Formula No. 20.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... add: A total of 2.0 gallons of either unleaded gasoline, rubber hydrocarbon solvent, kerosene, or deodorized kerosene; or any combination of these. (b) Authorized use. Restricted to fuel use, comparable to...

  10. 27 CFR 21.24 - Formula No. 20.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... add: A total of 2.0 gallons of either unleaded gasoline, rubber hydrocarbon solvent, kerosene, or deodorized kerosene; or any combination of these. (b) Authorized use. Restricted to fuel use, comparable to...

  11. 21 CFR 822.20 - What are the consequences if I fail to submit a postmarket surveillance plan, my plan is...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false What are the consequences if I fail to submit a postmarket surveillance plan, my plan is disapproved and I fail to submit a new plan, or I fail to conduct... Review and Action § 822.20 What are the consequences if I fail to submit a postmarket surveillance plan...

  12. 21 CFR 822.20 - What are the consequences if I fail to submit a postmarket surveillance plan, my plan is...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false What are the consequences if I fail to submit a postmarket surveillance plan, my plan is disapproved and I fail to submit a new plan, or I fail to conduct... Review and Action § 822.20 What are the consequences if I fail to submit a postmarket surveillance plan...

  13. 21 CFR 822.20 - What are the consequences if I fail to submit a postmarket surveillance plan, my plan is...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false What are the consequences if I fail to submit a postmarket surveillance plan, my plan is disapproved and I fail to submit a new plan, or I fail to conduct... Review and Action § 822.20 What are the consequences if I fail to submit a postmarket surveillance plan...

  14. 21 CFR 822.20 - What are the consequences if I fail to submit a postmarket surveillance plan, my plan is...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false What are the consequences if I fail to submit a postmarket surveillance plan, my plan is disapproved and I fail to submit a new plan, or I fail to conduct... Review and Action § 822.20 What are the consequences if I fail to submit a postmarket surveillance plan...

  15. 21 CFR 822.20 - What are the consequences if I fail to submit a postmarket surveillance plan, my plan is...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false What are the consequences if I fail to submit a postmarket surveillance plan, my plan is disapproved and I fail to submit a new plan, or I fail to conduct... Review and Action § 822.20 What are the consequences if I fail to submit a postmarket surveillance plan...

  16. A new species of Ischyodus (Chondrichthyes: Holocephali: Callorhynchidae) from Upper Maastrichtian Shallow marine facies of the Fox Hills and Hell Creek Formations, Williston basin, North Dakota, USA

    USGS Publications Warehouse

    Hoganson, J.W.; Erickson, J.M.

    2005-01-01

    A new species of chimaeroid, Ischyodus rayhaasi sp. nov., is described based primarily upon the number and configuration of tritors on palatine and mandibular tooth plates. This new species is named in honour of Mr Raymond Haas. Fossils of I. rayhaasi have been recovered from the Upper Maastrichtian Fox Hills Formation and the Breien Member and an unnamed member of the Hell Creek Formation at sites in south-central North Dakota and north-central South Dakota, USA. Ischyodus rayhaasi inhabited shallow marine waters in the central part of the Western Interior Seaway during the latest Cretaceous. Apparently it was also present in similar habitats at that time in the Volga region of Russia. Ischyodus rayhaasi is the youngest Cretaceous species Ischyodus known to exist before the Cretaceous/Tertiary extinction, and the species apparently did not survive that event. It was replaced by Ischyodus dolloi, which is found in the Paleocene Cannonball Formation of the Williston Basin region of North Dakota and is widely distributed elsewhere. ?? The Palaeontological Association.

  17. Solar-geophysical activity reports for STIP (study of travelling interplanetary phenomena) Interval 15, 12-21 February 1984 ground-level event and STIP Interval 16, 20 April-4 May 1984 Forbush decrease

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Coffey, H.E.; Allen, J.H.

    1987-07-01

    Contents include: solar-geophysical activity reports for STIP Interval XV 12-21 February 1984 ground-level event and STIP interval XVI 20 April-4 May 1984 Forbush decrease; overview of solar-terrestrial physics phenomena for STIP interval XV (12-21 February 1984) and STIP interval XVI (20 April-4 May 1984) (solar optical reports, solar radio events, spacecraft observations, cosmic ray observations, ionosphere, geomagnetism).

  18. 40 CFR 264.231 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.231 Section 264.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Surface Impoundments § 264.231 Special...

  19. 40 CFR 264.317 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.317 Section 264.317 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Landfills § 264.317 Special requirements for...

  20. 40 CFR 264.317 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.317 Section 264.317 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Landfills § 264.317 Special requirements for...

  1. 40 CFR 264.231 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.231 Section 264.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Surface Impoundments § 264.231 Special...

  2. 40 CFR 264.231 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.231 Section 264.231 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Surface Impoundments § 264.231 Special...

  3. 40 CFR 264.317 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.317 Section 264.317 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Landfills § 264.317 Special requirements for...

  4. 40 CFR 264.283 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.283 Section 264.283 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment § 264.283 Special requirements...

  5. 40 CFR 264.283 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.283 Section 264.283 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment § 264.283 Special requirements...

  6. 40 CFR 264.283 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.283 Section 264.283 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment § 264.283 Special requirements...

  7. 40 CFR 264.283 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.283 Section 264.283 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Land Treatment § 264.283 Special requirements...

  8. Improving irrigation management in L'Horta Nord (Valencia, Spain)

    NASA Astrophysics Data System (ADS)

    Pascual-Seva, Nuria; San Bautista, Alberto; López-Galarza, Salvador; Maroto, Jose Vicente; Pascual, Bernardo

    2014-05-01

    L'Horta Nord is an important irrigation district in Valencia (Spain), especially for vegetable crops. The traditional cropping pattern in the region consists of a rotation of chufa with crops such as potato, onion, lettuce, escarole and red cabbage, being all these crops furrow irrigated. Currently, the quality of the water used is acceptable, water is not expensive and there are no limitations on supply. Consequently, growers are not aware of the volumes of water used, application efficiencies, nor water productivity for any of the crops cited. The European Framework Directive 2000/60, based on the precautionary principle, considers preventive action for measures to be taken; moreover, drought periods are becoming more frequent and extended, and water is being diverted to other uses. Thus, water use is an issue to improve. In this sense, the current situation of the irrigation in the area is analysed using chufa (Cyperus esculentus L. var. sativus Boeck.) as representative of the crops, since most of the crops in the area have shallow root systems, as chufa, which are irrigated in similar patterns. In order to analyse the irrigation performance of the traditional chufa crop as well as to achieve more sustainable results, different studies have been carried out, during the last decade. Efforts have been directed to increase water productivity, increasing yield and minimising the volumes of water applied. Different planting configurations and different irrigation thresholds, not only in furrow irrigation but also in drip irrigation, are examples of how the irrigation performance could be improved. Herein is presented a two-year study, comparing, in both furrow and drip irrigation, two irrigation schedules based on the volumetric soil water content, which was continuously monitored using capacitance sensors. Yield was significantly affected by the growing season, the irrigation system and by the irrigation schedule, and by the second order interactions of the

  9. Psychosocial working conditions and sickness absence in a general population: a cohort study of 21,834 workers in Norway (The HUNT Study).

    PubMed

    Strømholm, Tonje; Pape, Kristine; Ose, Solveig Osborg; Krokstad, Steinar; Bjørngaard, Johan Håkon

    2015-04-01

    To examine the associations between psychosocial working conditions and sickness absence. Data for 21,834 employed adults from the Nord-Trøndelag Health Study (HUNT) were linked to the sickness benefit register and sickness absence during 1 year after survey participation was analyzed with logistic regression. A one unit change on a 0 to 3 self-reported job demand scale was associated with a fully adjusted 24% and 25% increased odds of sickness absence in men and women, respectively. A one unit change on a 0 to 3 scale for self-reported support at work was associated with a fully adjusted 13% and 17% reduced odds of sickness absence in men and women, respectively. The results of this study indicate that demands, and to some extent support, at work might influence sickness absence-also when adjusting for a detailed categorization of occupations.

  10. 21 CFR 107.20 - Directions for use.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION INFANT FORMULA Labeling § 107.20 Directions for use. In addition to the applicable labeling... Before Opening”; (3) “Sterilization” of water, bottle, and nipples when necessary for preparing infant...

  11. 21 CFR 20.90 - Disclosure to contractors.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... INFORMATION Limitations on Exemptions § 20.90 Disclosure to contractors. (a) Data and information otherwise... of such data and information as Food and Drug Administration employees. (b) A written agreement between the Food and Drug Administration and any contractor shall be entered into before data and...

  12. 21 CFR 20.90 - Disclosure to contractors.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... INFORMATION Limitations on Exemptions § 20.90 Disclosure to contractors. (a) Data and information otherwise... of such data and information as Food and Drug Administration employees. (b) A written agreement between the Food and Drug Administration and any contractor shall be entered into before data and...

  13. 40 CFR 264.259 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.259 Section 264.259 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Waste Piles § 264.259 Special requirements for...

  14. 40 CFR 264.259 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.259 Section 264.259 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Waste Piles § 264.259 Special requirements for...

  15. 40 CFR 264.259 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.259 Section 264.259 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Waste Piles § 264.259 Special requirements for...

  16. 21 CFR 1210.20 - Application for permit.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... FEDERAL IMPORT MILK ACT Permit Control § 1210.20 Application for permit. Application for a permit to ship or transport milk or cream into the United States shall be made by the actual shipper upon forms...

  17. 21 CFR 1210.20 - Application for permit.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... FEDERAL IMPORT MILK ACT Permit Control § 1210.20 Application for permit. Application for a permit to ship or transport milk or cream into the United States shall be made by the actual shipper upon forms...

  18. 40 CFR 264.231 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.231 Section 264.231 Protection of Environment... chemical characteristics of the wastes, including their potential to migrate through soil or to volatilize...

  19. CDC20 maintains tumor initiating cells

    PubMed Central

    Xie, Qi; Wu, Qiulian; Mack, Stephen C.; Yang, Kailin; Kim, Leo; Hubert, Christopher G.; Flavahan, William A.; Chu, Chengwei; Bao, Shideng; Rich, Jeremy N.

    2015-01-01

    Glioblastoma is the most prevalent and lethal primary intrinsic brain tumor. Glioblastoma displays hierarchical arrangement with a population of self-renewing and tumorigenic glioma tumor initiating cells (TICs), or cancer stem cells. While non-neoplastic neural stem cells are generally quiescent, glioblastoma TICs are often proliferative with mitotic control offering a potential point of fragility. Here, we interrogate the role of cell-division cycle protein 20 (CDC20), an essential activator of anaphase-promoting complex (APC) E3 ubiquitination ligase, in the maintenance of TICs. By chromatin analysis and immunoblotting, CDC20 was preferentially expressed in TICs relative to matched non-TICs. Targeting CDC20 expression by RNA interference attenuated TIC proliferation, self-renewal and in vivo tumor growth. CDC20 disruption mediated its effects through induction of apoptosis and inhibition of cell cycle progression. CDC20 maintains TICs through degradation of p21CIP1/WAF1, a critical negative regulator of TICs. Inhibiting CDC20 stabilized p21CIP1/WAF1, resulting in repression of several genes critical to tumor growth and survival, including CDC25C, c-Myc and Survivin. Transcriptional control of CDC20 is mediated by FOXM1, a central transcription factor in TICs. These results suggest CDC20 is a critical regulator of TIC proliferation and survival, linking two key TIC nodes – FOXM1 and p21CIP1/WAF1 — elucidating a potential point for therapeutic intervention. PMID:25938542

  20. 21 CFR 1.20 - Presence of mandatory label information.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... information. The term package means any container or wrapping in which any food, drug, device, or cosmetic is...) of the Family Smoking Prevention and Tobacco Control Act (21 U.S.C. 387(13)) defining “package,” the term package means any container or wrapping in which any food, drug, device, or cosmetic is enclosed...

  1. Source tracing of fluvial suspended sediments by magnetic and geochemical particle characterization: example of the Canche watershed (Nord-Pas-de-Calais, France)

    NASA Astrophysics Data System (ADS)

    Patault, Edouard; Alary, Claire; Franke, Christine; Gauthier, Arnaud; Abriak, Nor-Edine

    2016-04-01

    In France, erosion by water run-off is estimated to 1.5 t ha-1yr-1 and can exceed 10 t ha-1yr-1 in large growing areas, such as the North of France (Nord-Pas-de-Calais). In this region, the Canche watershed (1294 km2) sustains heavy loss of fertile soils. The land use is mainly dominated by arable lands (80%) and in 2013, 104 kt of suspended sediment transited to the estuary. As demonstrated in literature, agricultural soil erosion leads to the gradual disappearance and depletion of fertile soil, which constitute a non-renewable resource at human time scale. Additionally, water erosion can significantly damage the aquatic habitat and can be responsible for the input of nutrients, bacteria, pesticides, heavy metals and radionuclides into surface waters. Conscious of these effects, many programs have emerged in the Nord-Pas-de-Calais to reduce erosion. This study presents a combination of environmental magnetic proxy parameters and geochemical analyses on sediments and suspended particulate matter. The aim is to develop effective tools to trace erosion by water run-off and quantify this process. In order to identify the respective sediment sources in the Canche watershed, sediment trap samples of suspended particulate matter were recovered at key positions along the Canche watershed. The preliminary results show that magnetic concentration (Mrs) shows typical values for the agricultural soils in the region, but these variations in magnetic concentrations and total irons concentrations are not always correlated, which may be explained by the iron speciation. In calculating the so-called S-ratio for each sample we can distinguish changes in magneto-mineralogy (and thus iron speciation) from magnetite-dominated assemblages in the mainstream Canche (naturel background signal) to high-coercivity-dominated assemblages in the tributaries, typical for soil erosion material rich in hematite/goethite. In combination with the element concentrations from ICP analyses, this proxy

  2. Isolation of a new anti-inflammatory 20, 21, 22, 23, 24, 25, 26, 27-octanorcucurbitacin-type triterpene from Ibervillea sonorae.

    PubMed

    Jardón-Delgado, Angel; Magos-Guerrero, Gil Alfonso; Martínez-Vázquez, Mariano

    2014-01-01

    A new cucurbitane-type triterpene, 20, 21, 22, 23, 24, 25, 26, 27-octanorcucurbita-5-ene-3, 11, 16-trione (1), named kinoin D, was isolated from the roots of the medicinal plant Ibervillea sonorae, (wereque). The structure of 1 was established on the basis of extensive NMR and MS studies. In addition, the known kinoins B (3) and C (5) were isolated, as were 16alpha-20,25-trihydroxy-3alpha-(2-O-alpha-L-rhamnopyranosiyl-D-glucopyranosyloxy)-(10alpha)-cucurbit-5-en-11,22-dione (6), (22S)-16alpha,22-diacetoxy-20,25-dihydroxy-3alpha-[3,4,6-tri-O-acetyl-2-O-(2,3,4-tri-O-acetyl-alpha-L-rhamnopyranosyl)-beta-glucopyranosyl]-(10alpha)-cucurbita-5,23t-dien-11-one (7) and 16alpha-acetoxy-20,25-dihydroxy-3alpha-[3,4,6-tri-O-acetyl-2-O-(2,3,4,-tri-O-acetyl-alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl]-(10alpha)-cucurbita-5-ene-11,22-dione (8). Compound 1 exhibited anti-inflammatory activity in TPA-induced edema in mice.

  3. 40 CFR 264.283 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.283 Section 264.283 Protection of Environment... characteristics of the wastes, including their potential to migrate through soil or to volatilize or escape into...

  4. 40 CFR 264.317 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.317 Section 264.317 Protection of Environment..., including their potential to migrate through the soil or to volatilize or escape into the atmosphere; (2...

  5. 40 CFR 264.259 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27. 264.259 Section 264.259 Protection of Environment... through soil or to volatilize or escape into the atmosphere; (2) The attenuative properties of underlying...

  6. Familial translocation t(6;20)(p21;p13) resulting in partial trisomy 6p and partial monosomy 20p: report of a new case and review of the literature.

    PubMed

    Berner, A L; Bağci, S; Wohlleber, E; Engels, E; Müller, A; Bartmann, P; Weber, R G; Reutter, H

    2012-01-01

    Carriers of completely balanced chromosomal translocations have all necessary genetic information. Nevertheless, because of the possibility of maldistribution during gametogenesis, they are at increased risk for infertility, miscarriage, stillbirth or having a child with congenital anomalies including mental retardation. As postnatal clinical reports are infrequent, prediction of clinical course for specific unbalanced karyotypes diagnosed during pregnancy remains difficult. Here, we report the 6th case of partial trisomy 6p and partial monosomy 20p due to an unbalanced adjacent-1 segregation of the rare familial translocation t(6;20)(p21;p13). We give a thorough clinical description of the present case, demonstrating broad phenotypic overlap with the 5 previously published cases reviewed here, providing important data on postnatal outcome. Copyright © 2012 S. Karger AG, Basel.

  7. Atmospheric 21Ne abundance determined by the Helix-MC Plus mass spectrometer

    NASA Astrophysics Data System (ADS)

    Honda, M.; Zhang, X.; Phillips, D.; Hamilton, D.; Deerberg, M.; Schwieters, J. B.

    2014-12-01

    Analyses of noble gas isotopes by multi-collector, high resolution mass spectrometry have the potential to revolutionise applications in the cosmo-geo-sciences. The Helix-MC Plus noble gas mass spectrometer installed at the Australian National University (ANU) is equipped with unique high mass resolution collectors [mass resolution (MR): ~1,800 and mass resolving power (MRP): ~8,000], including fixed axial (Ax), adjustable high mass (H2) and adjustable low mass (L2) detectors. The high mass resolution of the L2, Ax and H2 collectors permits complete separation of 20Ne (measured on L2 detector) from doubly charged interfering 40Ar (required MR of 1,777), 1H19F (MR = 1450), 1H218O (MR = 894) and partial separation of the 21Ne peak (on Ax detector) from interfering 20Ne1H (MR = 3,271), and 22Ne (on H2 detector) from interfering doubly charged CO2 (MR = 6,231). Because of the high MRP of ~8,000, 21Ne can be measured, essentially without interference from 20Ne1H, by setting the magnet position on a 20Ne1H interference-free position. This capability provides an important opportunity to re-evaluate the 21Ne abundance in the atmosphere. Our analyses demonstrate that 20Ne1H contributes ~4% to atmospheric 21Ne measurements, with the corresponding production ratio of 20Ne1H to 20Ne being ~1E-4. We calculate a new atmospheric 21Ne/20Ne ratio of 0.00287 relative to an atmospheric 22Ne/20Ne ratio of 0.102; this new value is distinctly lower than the current IUPAC recommended 21Ne/20Ne value of 0.00298. There are several significant implications ensuing from the newly determined atmospheric 21Ne abundance. For example, in the area of Earth sciences the most critical issue relates to cosmogenic 21Ne surface exposure ages, which involve the calculation of 21Ne concentrations from excess 21Ne, relative to the atmospheric 21Ne/20Ne ratio. For young samples, where cosmogenic 21Ne contents are small and the 21Ne/20Ne ratio is close to the atmospheric value, the revised value could

  8. Transforming Pedagogies: Integrating 21st Century Skills and Web 2.0 Technology

    ERIC Educational Resources Information Center

    Tucker, Shelia Y.

    2014-01-01

    According to (P21), Partnership for 21st Century Skills (n.d.), unless the gap is bridged between how students learn and how they live, today's education system will face irrelevance. The way people work and live has been transformed by demographic, economic, political, technological, and informational forces. Schools must adapt to these…

  9. First Results with TIGRESS and Accelerated Radioactive Ion Beams from ISAC: Coulomb Excitation of 20,21,29Na

    NASA Astrophysics Data System (ADS)

    Schumaker, M. A.; Hurst, A. M.; Svensson, C. E.; Wu, C. Y.; Becker, J. A.; Cline, D.; Hackman, G.; Pearson, C. J.; Stoyer, M. A.; Andreyev, A.; Austin, R. A. E.; Ball, G. C.; Bandyopadhyay, D.; Barton, C. J.; Boston, A. J.; Boston, H. C.; Buchmann, L.; Churchman, R.; Cifarelli, F.; Colosimo, S. J.; Cooper, R. J.; Cross, D. S.; Dashdorj, D.; Demand, G. A.; Dimmock, M. R.; Djongolov, M.; Drake, T. E.; Finlay, P.; Gallant, A. T.; Garrett, P. E.; Gray-Jones, C.; Green, K. L.; Grint, A. N.; Grinyer, G. F.; Harkness, L. J.; Hayes, A. B.; Kanungo, R.; Leach, K. G.; Kulp, W. D.; Lisetskiy, A. F.; Lee, G.; Lloyd, S.; Maharaj, R.; Martin, J.-P.; Millar, B. A.; Moisan, F.; Morton, A. C.; Mythili, S.; Nelson, L.; Newman, O.; Nolan, P. J.; Orce, J. N.; Oxley, D. C.; Padilla-Rodal, E.; Phillips, A. A.; Porter-Peden, M.; Ressler, J. J.; Rigby, S. V.; Roy, R.; Ruiz, C.; Sarazin, F.; Scraggs, D. P.; Sumithrarachchi, C. S.; Triambak, S.; Waddington, J. C.; Walker, P. M.; Wan, J.; Whitbeck, A.; Williams, S. J.; Wong, J.; Wood, J. L.

    2009-03-01

    The TRIUMF-ISAC Gamma-Ray Escape Suppressed Spectrometer (TIGRESS) is a state-of-the-art γ-ray spectrometer being constructed at the ISAC-II radioactive ion beam facility at TRIUMF. TIGRESS will be comprised of twelve 32-fold segmented high-purity germanium (HPGe) clover-type γ-ray detectors, with BGO/CsI(Tl) Compton-suppression shields, and is currently operational at ISAC-II in an early-implementation configuration of six detectors. Results have been obtained for the first experiments performed using TIGRESS, which examined the A = 20, 21, and 29 isotopes of Na by Coulomb excitation.

  10. Etude de la qualité bactériologique de l’eau utilisée dans l’industrie agroalimentaire dans le Nord du Maroc

    PubMed Central

    Haijoubi, El Houcine; Benyahya, Fatiha; Bendahou, Abdrezzak; Essadqui, Faima Zahra; Behhari, Mohammed El; El Mamoune, Ahmed Fouad; Ghailani, Naima Nourouti; Mechita, Mohcine Bennani; Barakat, Amina

    2017-01-01

    Introduction L'eau est utilisée d'une façon primordiale dans tout le processus de la fabrication des produits alimentaires. Les industries agroalimentaires du Nord du Maroc utilisent différentes sources d'eaux mais l'eau de réseau public et l'eau de puits sont les principales sources d'eau utilisée. Cette eau peut s'avérer la source principale des éventuelles contaminations et altérations des aliments. Notre but est d'évaluer la qualité bactériologique de l'eau utilisée par les industries agroalimentaires dans la région du Nord du Maroc, d'identifier les différents germes responsables de la pollution de ces eaux et de définir les principales causes de cette pollution. Méthodes Des échantillons d'eau prélevés aux robinets ou des puits ont été analysés pour la recherche des germes indicateurs de la pollution (coliformes totaux (CT), coliformes fécaux (CF), entérocoques intestinaux (E), microorganismes revivifiables (MOR), anaérobies sulfitoréducteurs) et les germes pathogènes (Salmonelles, Staphylocoques, Pseudomonas aeruginosa). Le dénombrement des bactéries a été fait par la technique de filtration et par incorporation en milieu solide en surfusion. Résultats Les résultats ont montré que les eaux du réseau public ont été de qualité bactériologique satisfaisante tandis que 40% des eaux des puits ont été non conformes aux normes à cause de la présence des indicateurs de pollution CT, CF, E et MOR. En revanche, les germes pathogènes, en particulier les Salmonelles, ont été absents dans les eaux de tous les puits analysés. Conclusion La pollution de ces puits a été généralement liée au non-respect des conditions de puisage hygiéniques. La qualité bactériologique des eaux de ces puits peut être améliorée par une protection adéquate. PMID:28450992

  11. Educating about Social Issues in the 20th and 21st Centuries: A Critical Annotated Bibliography. Research in Curriculum and Instruction. Volume 1

    ERIC Educational Resources Information Center

    Totten, Samuel, Ed.; Pedersen, Jon, Ed.

    2012-01-01

    Educating About Social Issues in the 20th and 21st Centuries: A Critical Annotated Bibliography, is comprised of critical essays accompanied by annotated bibliographies on a host of programs, models, strategies and concerns vis-a-vis teaching and learning about social issues facing society. The primary goal of the book is to provide undergraduate…

  12. 21 CFR 13.20 - Submissions to a Board.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... to be filed with the Division of Dockets Management under § 10.20. (b) The person making a submission... 13.45. Submissions of documentary data and information need not be sent to each participant, but any...

  13. Downscaling 20th century flooding events in complex terrain (Switzerland) using the WRF regional climate model

    NASA Astrophysics Data System (ADS)

    Heikkilä, Ulla; Gómez Navarro, Juan Jose; Franke, Jörg; Brönnimann, Stefan; Cattin, Réne

    2016-04-01

    Switzerland has experienced a number of severe precipitation events during the last few decades, such as during the 14-16 November of 2002 or during the 21-22 August of 2005. Both events, and subsequent extreme floods, caused fatalities and severe financial losses, and have been well studied both in terms of atmospheric conditions leading to extreme precipitation, and their consequences [e.g. Hohenegger et al., 2008, Stucki et al., 2012]. These examples highlight the need to better characterise the frequency and severity of flooding in the Alpine area. In a larger framework we will ultimately produce a high-resolution data set covering the entire 20th century to be used for detailed hydrological studies including all atmospheric parameters relevant for flooding events. In a first step, we downscale the aforementioned two events of 2002 and 2005 to assess the model performance regarding precipitation extremes. The complexity of the topography in the Alpine area demands high resolution datasets. To achieve a sufficient detail in resolution we employ the Weather Research and Forecasting regional climate model (WRF). A set of 4 nested domains is used with a 2-km resolution horizontal resolution over Switzerland. The NCAR 20th century reanalysis (20CR) with a horizontal resolution of 2.5° serves as boundary condition [Compo et al., 2011]. First results of the downscaling the 2002 and 2005 extreme precipitation events show that, compared to station observations provided by the Swiss Meteorological Office MeteoSwiss, the model strongly underestimates the strength of these events. This is mainly due to the coarse resolution of the 20CR data, which underestimates the moisture fluxes during these events. We tested driving WRF with the higher-resolved NCEP reanalysis and found a significant improvement in the amount of precipitation of the 2005 event. In a next step we will downscale the precipitation and wind fields during a 6-year period 2002-2007 to investigate and

  14. 21 CFR 556.20 - 2-Acetylamino-5-nitrothiazole.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD Specific Tolerances for Residues of New Animal Drugs § 556.20 2-Acetylamino-5-nitrothiazole. A tolerance of 0.1 part... tissues of turkeys. ...

  15. 12 CFR 217.21 - Minority interest.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 2 2014-01-01 2014-01-01 false Minority interest. 217.21 Section 217.21 Banks... OF BOARD-REGULATED INSTITUTIONS Definition of Capital § 217.21 Minority interest. (a) Applicability. For purposes of § 217.20, a Board-regulated institution is subject to the minority interest...

  16. 12 CFR 324.21 - Minority interest.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Minority interest. 324.21 Section 324.21 Banks... ADEQUACY OF FDIC-SUPERVISED INSTITUTIONS Definition of Capital § 324.21 Minority interest. (a) Applicability. For purposes of § 324.20, an FDIC-supervised institution is subject to the minority interest...

  17. Identification of 17,20beta,21-trihydroxy-4-pregnen-3-one as an oocyte maturation-inducing steroid in black porgy, Acanthopagrus schlegeli.

    PubMed

    Yueh, Wen-Shiun; Thomas, Peter; Chang, Ching-Fong

    2005-02-01

    The identity of the maturation-inducing steroid (MIS) in black porgy, Acanthopagrus schlegeli, a marine protandrous teleost, is unknown. Previous studies demonstrated that two teleost MISs, the progestins 17,20beta,21-trihydroxy-4-pregnen-3-one (20beta-S) and 17,20beta-dihydroxy-4-pregnen-3-one (DHP) can induce maturation of black porgy oocytes in vitro. The purpose of the present study was to identify the major progestin produced during oocyte maturation (OM) in black porgy and investigate whether its secretion increases during this process. Females were injected twice with a LHRH analog to induce OM. Ovarian follicles undergoing OM were incubated in vitro with tritiated [3H]pregnenolone precursor and the tritiated products were extracted, purified, and identified by HPLC, TLC, acetylation, and recrystallization. Significant amounts of tritiated products were biosynthesized from [3H]pregnenolone that co-migrated with 20beta-S but not with DHP on HPLC and TLC. Similar TLC profiles were obtained with the tritiated products isolated from the HPLC/TLC 20beta-S fraction and standard 20beta-S after the acetylation reaction. The identity of the tritiated products as 20beta-S was confirmed by recrystallization. 20beta-S had a slightly higher potency than DHP in the inducing in vitro final oocyte maturation. Plasma 20beta-S concentrations increased significantly during the oocyte maturation after injection with a LHRH analog. The present data suggest that 20beta-S is the MIS in black porgy.

  18. Hypertension in Pregnancy and Offspring Cardiovascular Risk in Young Adulthood: Prospective and Sibling Studies in the HUNT Study (Nord-Trøndelag Health Study) in Norway.

    PubMed

    Alsnes, Ingvild V; Vatten, Lars J; Fraser, Abigail; Bjørngaard, Johan Håkon; Rich-Edwards, Janet; Romundstad, Pål R; Åsvold, Bjørn O

    2017-04-01

    Women with hypertensive disorders in pregnancy are at increased lifetime risk for cardiovascular disease. We examined the offspring's cardiovascular risk profile in young adulthood and their siblings' cardiovascular risk profile. From the HUNT study (Nord-Trøndelag Health Study) in Norway, 15 778 participants (mean age: 29 years), including 210 sibling groups, were linked to information from the Medical Birth Registry of Norway. Blood pressure, anthropometry, serum lipids, and C-reactive protein were assessed. Seven hundred and six participants were born after exposure to maternal hypertension in pregnancy: 336 mothers had gestational hypertension, 343 had term preeclampsia, and 27 had preterm preeclampsia. Offspring whose mothers had hypertension in pregnancy had 2.7 (95% confidence interval, 1.8-3.5) mm Hg higher systolic blood pressure, 1.5 (0.9-2.1) mm Hg higher diastolic blood pressure, 0.66 (0.31-1.01) kg/m 2 higher body mass index, and 1.49 (0.65-2.33) cm wider waist circumference, compared with offspring of normotensive pregnancies. Similar differences were observed for gestational hypertension and term preeclampsia. Term preeclampsia was also associated with higher concentrations of non-high-density lipoprotein cholesterol (0.14 mmol/L, 0.03-0.25) and triglycerides (0.13 mmol/L, 0.06-0.21). Siblings born after a normotensive pregnancy had nearly identical risk factor levels as siblings born after maternal hypertension. Offspring born after maternal hypertension in pregnancy have a more adverse cardiovascular risk profile in young adulthood than offspring of normotensive pregnancies. Their siblings, born after a normotensive pregnancy, have a similar risk profile, suggesting that shared genes or lifestyle may account for the association, rather than an intrauterine effect. All children of mothers who have experienced hypertension in pregnancy may be at increased lifetime risk of cardiovascular disease. © 2017 American Heart Association, Inc.

  19. 12 CFR 237.20 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... the Board's Regulation K (12 CFR 211.21(n)). Major security-based swap participant has the same... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Definitions. 237.20 Section 237.20 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED...

  20. 50 CFR 20.22 - Closed seasons.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 6 2010-10-01 2010-10-01 false Closed seasons. 20.22 Section 20.22... PLANTS (CONTINUED) MIGRATORY BIRD HUNTING Taking § 20.22 Closed seasons. No person shall take migratory game birds during the closed season except as provided in part 21 of this chapter. [73 FR 65951, Nov. 5...

  1. 21 CFR 20.22 - Partial disclosure of records.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION General Policy § 20.22 Partial disclosure of records. (a) If a record contains both disclosable and nondisclosable information, the nondisclosable information will be deleted and the remaining...

  2. 21 CFR 20.22 - Partial disclosure of records.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION General Policy § 20.22 Partial disclosure of records. (a) If a record contains both disclosable and nondisclosable information, the nondisclosable information will be deleted and the remaining...

  3. 21 CFR 20.22 - Partial disclosure of records.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION General Policy § 20.22 Partial disclosure of records. (a) If a record contains both disclosable and nondisclosable information, the nondisclosable information will be deleted and the remaining...

  4. 21 CFR 20.22 - Partial disclosure of records.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION General Policy § 20.22 Partial disclosure of records. (a) If a record contains both disclosable and nondisclosable information, the nondisclosable information will be deleted and the remaining...

  5. Detailed study of sulfide scaling at La Courneuve Nord, a geothermal exploitation of the Paris basin, France

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Honegger, J.L.; Czernichowski-Lauriol, I.; Criaud, A.

    1989-01-01

    The fluid of the Dogger aquifer is always used through a closed loop formed by the production well, the heating plant and the injection well. After two or three years of exploitation of the geothermal doublets in the northern part of the Paris basin, scaling and plugging problems have appeared in some cases. The results of the detailed study carried out at La Courneuve Nord, a typical site of this area, are presented. The drawdown of production rate, scaling in the heat exchanger and the increase of injection pressure required a rapid decision for workover operations on the wells. Thesemore » cleaning operations and joint research studies allowed the authors to identify the cause of the plugging as well as to locate these deposits and to estimate their importance. After cleaning operations, the hydraulic properties of the reservoir seem to be recovered. Chemical and mineralogical analyses of these deposits identified the presence of a large variety of iron sulfide and a typical corrosion product. Biochemical and bacteriological studies show a very high content of micro-organisms. A chemical model, IPDEGAZ, is used to calculate the evolution of the saturation indexes of the fluid with respect to iron sulfide phases. The effects of parameters such as pressure, temperature, degassing and addition of iron by corrosion are simulated. The results of the observation and modeling approaches are compared.« less

  6. Webquest 2.0: Best Practices for the 21st Century

    ERIC Educational Resources Information Center

    Levin-Goldberg, Jennifer

    2014-01-01

    Over the last decade, WebQuests have grown in popularity in educational environments. In order to effectively implement a WebQuest in the classroom, best pedagogical practices must be employed; however, these best WebQuest practices should reflect the exigent 21st century skills students need to be successful, productive members of the global…

  7. Depressed Physical Performance Outlasts Hormonal Disturbances after Military Training.

    PubMed

    Hamarsland, Håvard; Paulsen, Gøran; Solberg, Paul A; Slaathaug, Ole Gunnar; Raastad, Truls

    2018-06-21

    The aim of this study was to investigate the effect of an arduous one-week military course on measures of physical performance, body composition and blood biomarkers. Participants were apprentices in an annual selection course for the Norwegian Special Forces. Fifteen soldiers (23±4 yrs., 1.81±0.06 m, 78±7 kg) completed a hell-week consisting of rigorous activity only interspersed by 2-3 hours of sleep per day. Testing was conducted before and 0, 1, 3, 7 and 14 days after the hell-week. Physical performance was measured as muscle strength and jump performance. Body composition was measured by bioelectrical impedance and blood samples were collected and analyzed for hormones, creatine kinase, and C-reactive protein. Body mass was reduced by 5.3±1.9 kg during the hell-week and returned to baseline within one week. Fat mass was reduced by 2.1±1.7 kg and muscle mass by 1.9±0.9 kg. Muscle strength in leg-press and bench-press was reduced by 20±9% and 9±7%, respectively, and both were ~10% lower than baseline after one week of recovery. Jump-height was reduced by 28±13% and was still 14±5% below baseline after 2 weeks of recovery. Testosterone was reduced by 70±12% and recovered gradually within a week. Cortisol was increased by 154±74%, and did not fully recover during the next week. IGF-1 was reduced by 51±10% and T3 and T4 by 12-30%, all recovered within a week. One-week arduous military exercise resulted in reductions in body mass and performance, as well as considerable hormonal disturbances. Our most important observation was that whereas the hormonal systems was normalized within one week of rest and proper nutrition, lower body strength and jump performance were still depressed after two weeks.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be

  8. 12 CFR 3.21 - Minority interest.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Minority interest. 3.21 Section 3.21 Banks and... Capital § 3.21 Minority interest. (a) Applicability. For purposes of § 3.20, a national bank or Federal savings association is subject to the minority interest limitations in this section if: (1) A consolidated...

  9. A Review of Chemical Warfare Agent (CWA) Detector Technologies and Commercial-Off-The-Shelf Items

    DTIC Science & Technology

    2009-03-01

    Environmental Health Perspectives 1994, 102, 18-38. 21. La Franchi , P., Chemical and Biological Weapons: The War from Hell. ADM September, 1995, pp 9-10...One-to-Five Gas Monitor with VOC Detection. In ENVCO Global . DSTO-GD-0570 98 152. MultiRAE Plus. In RAE Systems: San Jose, CA. 153. ToxiRAE Plus PID...158. Rippen, M., Chemical and Biological Agent Sensor/Detector Systems Technology Development for Applications in the Global War on Terrorism. In

  10. Non-random mating and convergence over time for alcohol consumption, smoking, and exercise: the Nord-Trøndelag Health Study.

    PubMed

    Ask, Helga; Rognmo, Kamilla; Torvik, Fartein Ask; Røysamb, Espen; Tambs, Kristian

    2012-05-01

    Spouses tend to have similar lifestyles. We explored the degree to which spouse similarity in alcohol use, smoking, and physical exercise is caused by non-random mating or convergence. We used data collected for the Nord-Trøndelag Health Study from 1984 to 1986 and prospective registry information about when and with whom people entered marriage/cohabitation between 1970 and 2000. Our sample included 19,599 married/cohabitating couples and 1,551 future couples that were to marry/cohabitate in the 14-16 years following data collection. All couples were grouped according to the duration between data collection and entering into marriage/cohabitation. Age-adjusted polychoric spouse correlations were used as the dependent variables in non-linear segmented regression analysis; the independent variable was time. The results indicate that spouse concordance in lifestyle is due to both non-random mating and convergence. Non-random mating appeared to be strongest for smoking. Convergence in alcohol use and smoking was evident during the period prior to marriage/cohabitation, whereas convergence in exercise was evident throughout life. Reduced spouse similarity in smoking with relationship duration may reflect secular trends.

  11. A historical cycle control comparison of two drospirenone-containing combined oral contraceptives: ethinylestradiol 30 μg/drospirenone 3 mg administered in a 21/7 regimen versus ethinylestradiol 20 μg/drospirenone 3 mg administered in a 24/4 regimen.

    PubMed

    Marr, Joachim; Gerlinger, Christoph; Kunz, Michael

    2012-05-01

    To compare the bleeding patterns and cycle control of an oral contraceptive (OC) containing ethinylestradiol (EE) 30 μg/drospirenone (drsp) 3mg administered in a 21/7 regimen versus a lower-dose OC containing EE 20 μg/drsp 3mg administered in a 24/4 regimen, using data from two identically designed studies. In the first study, 326 healthy women (18-35 years) received EE 30 μg/drsp 3mg in a 21/7 regimen. In the second study, 1027 healthy women (17-36 years) received EE 20 μg/drsp 3mg in a 24/4 regimen. Participants recorded bleeding using daily completed diaries over 13 treatment cycles. During cycles 1-12, the prevalence of scheduled withdrawal bleeding was lower with EE 20 μg/drsp 3mg 24/4 than with EE 30 μg/drsp 3mg 21/7 (82.0-91.7% versus 94.8-100.0% of women, respectively); moreover, a higher proportion of women reported a maximum intensity of light scheduled withdrawal bleeding with EE 20 μg/drsp 3mg 24/4 than with EE 30 μg/drsp 3mg 21/7 (30.9-39.0% versus 13.8-20.5% of women, respectively). In cycles 2-13, unscheduled intracyclic bleeding was reported by 7.7-13.8% of EE 20 μg/drsp 3mg 24/4 recipients and 3.8-7.9% of EE 30 μg/drsp 3mg 21/7 recipients; these were mainly single bleeding days. During reference periods 1-4, the mean number of bleeding episodes was similar between groups (3.1-3.3 episodes with EE 20 μg/drsp 3mg 24/4 versus 3.2 episodes with EE 30 μg/drsp 3mg 21/7). A low-dose 24/4 regimen OC containing EE 20 μg/drsp 3mg is generally comparable in terms of bleeding to a higher-dose 21/7 regimen OC containing EE30 μg/drsp 3mg. Between-treatment differences in bleeding intensity and unscheduled intracyclic bleeding rates were observed. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  12. Angular Motion of Projectiles with a Moving Internal Part.

    DTIC Science & Technology

    1977-02-01

    Ball Rotor T317 hellIntermal Projectile RingsM505 Fuze Quasi-linear Angular Motion N\\ ANSTRACT (-jCanhs si rveree side ff naeweemv end identify by...LIST OF FIGURES Figure Page 1. 20mm Shell T282E1 with Arming Ball Rotor .... .......... 20 2. Fast Mode Damping Rate for the 20mm T282E1...fuze has a spherical arming rotor in a cylindrical cavity with small but non-zero clearanc’es (Figure 1). The fourth sa.ell - the 8-inch T317 - showed

  13. Teaching Human Rights? "All Hell Will Break Loose!"

    ERIC Educational Resources Information Center

    Cassidy, Claire; Brunner, Richard; Webster, Elaine

    2014-01-01

    Human rights education is a prominent concern of a number of international organisations and has been dominant on the United Nations' agenda for the past 20 years. The UN Decade for Human Rights Education (1995-2004) has been followed by the World Programme for Human Rights Education (2005-ongoing) and the recently adopted UN Declaration on Human…

  14. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    A Russian doctor monitors Expedition 20 Flight Engineer Michael Barratt onboard a helicopter heading to Kustanay, Kazakhstan shortly after Barratt, Expedition 20 Commander Gennady Padalka, and spaceflight participant Guy Laliberté landed their Soyuz TMA-14 capsule near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  15. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    Expedition 20 Flight Engineer Michael Barratt rests in a chair and is checked by medical personnel shortly after he and Spaceflight participant Guy Laliberté, and Expedition 20 Commander Gennady Padalka landed in their Soyuz TMA-14 capsule near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  16. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    Expedition 20 Flight Engineer Michael Barratt signs an autograph inside a helicopter shortly after shortly after he and Expedition 20 Commander Gennady Padalka, and spaceflight participant Guy Laliberté landed their Soyuz TMA-14 capsule near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  17. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    Expedition 20 Flight Engineer Michael Barratt is carried in a chair to the medical tent shortly after he and Spaceflight participant Guy Laliberté, and Expedition 20 Commander Gennady Padalka landed in their Soyuz TMA-14 capsule near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  18. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    Astronaut Sunita WIlliams, left, talks with Expedition 20 Flight Engineer Michael Barratt onboard a helicopter shortly after shortly after he and Expedition 20 Commander Gennady Padalka, and spaceflight participant Guy Laliberté landed their Soyuz TMA-14 capsule near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  19. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    Expedition 20 Flight Engineer Michael Barratt signs the inside of his helicopter shortly after shortly after he and Expedition 20 Commander Gennady Padalka, and spaceflight participant Guy Laliberté landed their Soyuz TMA-14 capsule near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  20. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    Expedition 20 Flight Engineer Michael Barratt rests in a chair shortly after he and Spaceflight participant Guy Laliberté, and Expedition 20 Commander Gennady Padalka landed in their Soyuz TMA-14 capsule near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  1. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    Russian medical personnel monitor Expedition 20 Flight Engineer Michael Barratt onboard a helicopter heading to Kustanay, Kazakhstan shortly after Barratt, Expedition 20 Commander Gennady Padalka, and spaceflight participant Guy Laliberté landed their Soyuz TMA-14 capsule near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  2. Cyclin-dependent kinase inhibitor p20 controls circadian cell-cycle timing

    PubMed Central

    Laranjeiro, Ricardo; Tamai, T. Katherine; Peyric, Elodie; Krusche, Peter; Ott, Sascha; Whitmore, David

    2013-01-01

    Specific stages of the cell cycle are often restricted to particular times of day because of regulation by the circadian clock. In zebrafish, both mitosis (M phase) and DNA synthesis (S phase) are clock-controlled in cell lines and during embryo development. Despite the ubiquitousness of this phenomenon, relatively little is known about the underlying mechanism linking the clock to the cell cycle. In this study, we describe an evolutionarily conserved cell-cycle regulator, cyclin-dependent kinase inhibitor 1d (20 kDa protein, p20), which along with p21, is a strongly rhythmic gene and directly clock-controlled. Both p20 and p21 regulate the G1/S transition of the cell cycle. However, their expression patterns differ, with p20 predominant in developing brain and peak expression occurring 6 h earlier than p21. p20 expression is also p53-independent in contrast to p21 regulation. Such differences provide a unique mechanism whereby S phase is set to different times of day in a tissue-specific manner, depending on the balance of these two inhibitors. PMID:23569261

  3. Cyclin-dependent kinase inhibitor p20 controls circadian cell-cycle timing.

    PubMed

    Laranjeiro, Ricardo; Tamai, T Katherine; Peyric, Elodie; Krusche, Peter; Ott, Sascha; Whitmore, David

    2013-04-23

    Specific stages of the cell cycle are often restricted to particular times of day because of regulation by the circadian clock. In zebrafish, both mitosis (M phase) and DNA synthesis (S phase) are clock-controlled in cell lines and during embryo development. Despite the ubiquitousness of this phenomenon, relatively little is known about the underlying mechanism linking the clock to the cell cycle. In this study, we describe an evolutionarily conserved cell-cycle regulator, cyclin-dependent kinase inhibitor 1d (20 kDa protein, p20), which along with p21, is a strongly rhythmic gene and directly clock-controlled. Both p20 and p21 regulate the G1/S transition of the cell cycle. However, their expression patterns differ, with p20 predominant in developing brain and peak expression occurring 6 h earlier than p21. p20 expression is also p53-independent in contrast to p21 regulation. Such differences provide a unique mechanism whereby S phase is set to different times of day in a tissue-specific manner, depending on the balance of these two inhibitors.

  4. Highlights from the IV International Symposium of Thrombosis and Anticoagulation (ISTA), October 20-21, 2011, Salvador, Bahia, Brazil.

    PubMed

    Lopes, Renato D; Becker, Richard C; Newby, L Kristin; Peterson, Eric D; Hylek, Elaine M; Granger, Christopher B; Crowther, Mark; Wang, Tracy; Carvalho, Antonio C; Berwanger, Otavio; Giraldez, Roberto R; Feitosa, Gilson Soares; Ribeiro, Jorge Pinto; Darze, Eduardo; Kalil, Renato A K; Andrande, Marianna; Boas, Fabio Villas; Andrade, Jadelson; Rocha, Ana Thereza; Harrington, Robert A; Lopes, Antonio C; Garcia, David A

    2012-07-01

    To discuss and share knowledge about advances in the care of patients with thrombotic disorders, the Fourth International Symposium of Thrombosis and Anticoagulation was held in Salvador, Bahia, Brazil, from October 20-21, 2011. This scientific program was developed by clinicians for clinicians and was promoted by three major clinical research institutes: the Brazilian Clinical Research Institute, the Duke Clinical Research Institute of the Duke University School of Medicine, and Hospital do Coração Research Institute. Comprising 2 days of academic presentations and open discussion, the symposium had as its primary goal to educate, motivate, and inspire internists, cardiologists, hematologists, and other physicians by convening national and international visionaries, thought-leaders, and dedicated clinician-scientists. This paper summarizes the symposium proceedings.

  5. Chronicle of Higher Education. Volume 51, Number 20, January 21, 2005

    ERIC Educational Resources Information Center

    Chronicle of Higher Education, 2005

    2005-01-01

    "Chronicle of Higher Education" presents an abundant source of news and information for college and university faculty members and administrators. This January 21, 2005 issue of "Chronicle of Higher Education" includes the following articles: (1) "The Perils of Pursuing Prestige" (Lovett, Clara M.); (2) "A…

  6. Teaching of Psychology: Ideas and Innovations. Proceedings of the Annual Conference on Undergraduate Teaching of Psychology (23rd, Tarrytown, New York, March 20-21, 2009)

    ERIC Educational Resources Information Center

    Howell-Carter, Marya, Ed.; Gonder, Jennifer, Ed.

    2009-01-01

    The document is a summary of the conference proceedings for the 23rd Annual Farmingdale State College Teaching of Psychology Conference held on March 20-21, 2009 at the DoubleTree Hotel in Tarrytown, New York. The conference featured a keynote address by Dr. Jeffrey Nevid on Reaching and teaching the millennials: Helping today's students become…

  7. 28 CFR 552.21 - Types of force.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Types of force. 552.21 Section 552.21... Force and Application of Restraints on Inmates § 552.21 Types of force. (a) Immediate use of force. Staff may immediately use force and/or apply restraints when the behavior described in § 552.20...

  8. 38 CFR 21.150 - Reader service.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Special Rehabilitation Services § 21.150 Reader service. (a) Limitations on vision. A veteran considered... vision is 20/200 in both eyes; (2) Whose central vision is greater than 20/200 but whose field of vision... greater than 20 degrees; or (3) With impaired vision, whose condition or prognosis indicates that the...

  9. 38 CFR 21.150 - Reader service.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Special Rehabilitation Services § 21.150 Reader service. (a) Limitations on vision. A veteran considered... vision is 20/200 in both eyes; (2) Whose central vision is greater than 20/200 but whose field of vision... greater than 20 degrees; or (3) With impaired vision, whose condition or prognosis indicates that the...

  10. [{(Mo)Mo5O21(H2O)3(SO4)}12(VO)30(H2O)20]36-: a molecular quantum spin icosidodecahedron.

    PubMed

    Botar, Bogdan; Kögerler, Paul; Hill, Craig L

    2005-07-07

    Self-assembly of aqueous solutions of molybdate and vanadate under reducing, mildly acidic conditions results in a polyoxomolybdate-based {Mo72V30} cluster compound Na8K16(VO)(H2O)5[K10 subset{(Mo)Mo5O21(H2O)3(SO4)}12(VO)30(H2O)20].150H2O, 1, a quantum spin-based Keplerate structure.

  11. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    A Russian Search and Rescue team All Terrain Vehicle (ATV) brings Expedition 20 Flight Engineer Michael Barratt to his helicopter shortly after he and Expedition 20 Commander Gennady Padalka, and spaceflight participant Guy Laliberté landed their Soyuz TMA-14 capsule near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  12. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    Russian Search and Rescue helicopters are seen out the window of another helicopter carrying Expedition 20 Flight Engineer Michael Barratt shortly after shortly after he and Expedition 20 Commander Gennady Padalka, and spaceflight participant Guy Laliberté landed their Soyuz TMA-14 capsule near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  13. 21 CFR 522.1680 - Oxytocin injection.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Oxytocin injection. 522.1680 Section 522.1680 Food... Oxytocin injection. (a) Specifications. Each milliliter (mL) of solution contains 20 USP units oxytocin. (b... 10 to 20. Sows 0.25 to 1.0 5 to 20. (2) Indications for use. Oxytocin may be used as a uterine...

  14. 21 CFR 347.20 - Permitted combinations of active ingredients.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... SERVICES (CONTINUED) DRUGS FOR HUMAN USE SKIN PROTECTANT DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Active Ingredients § 347.20 Permitted combinations of active ingredients. (a) Combinations of skin...) Combinations of skin protectant and external analgesic active ingredients. Any one (two when required to be in...

  15. 21 CFR 1020.20 - Cold-cathode gas discharge tubes.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) RADIOLOGICAL HEALTH PERFORMANCE STANDARDS FOR IONIZING RADIATION EMITTING PRODUCTS § 1020.20 Cold-cathode gas... discharge tubes designed to demonstrate the effects of a flow of electrons or the production of x-radiation... cathode. Exit beam means that portion of the radiation which passes through the aperture resulting from...

  16. 21 CFR 20.50 - Nonspecific and overly burdensome requests.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... policy reasons justifying the requests. A decision on the processing of such a request for information... PUBLIC INFORMATION Procedures and Fees § 20.50 Nonspecific and overly burdensome requests. The Food and... taking into account the staff-hours required, the tasks from which these resources must be diverted, the...

  17. Potentially dangerous 24-hour rainfall in the Provadiyska vally system at the end of the 20th and early 21st Centuries

    NASA Astrophysics Data System (ADS)

    Vladev, Dimitar

    2018-03-01

    Extreme rainfalls are of paramount importance for the formation of river springs and, consequently, the occurrence of spills and floods. The article presents the results of a case study of the potentially dangerous 24-hour eruptions in the Provadiyska valley system from the end of the 20th and the beginning of the 21st century. Particular attention is paid to the morphometric parameters and the configuration of the river-valley supply network of the Provadiyska river. On this basis, there are defined areas in which there are favorable conditions for forming high river waves.

  18. 21 CFR 20.46 - Waiver or reduction of fees.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... information to the public. An unsupported claim to be doing research for a book or article does not.... The interest of a representative of the news media in using the information for news dissemination... INFORMATION Procedures and Fees § 20.46 Waiver or reduction of fees. (a) Standard. The Assistant Commissioner...

  19. 21 CFR 20.46 - Waiver or reduction of fees.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... information to the public. An unsupported claim to be doing research for a book or article does not.... The interest of a representative of the news media in using the information for news dissemination... INFORMATION Procedures and Fees § 20.46 Waiver or reduction of fees. (a) Standard. The Assistant Commissioner...

  20. 21 CFR 20.46 - Waiver or reduction of fees.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... information to the public. An unsupported claim to be doing research for a book or article does not.... The interest of a representative of the news media in using the information for news dissemination... INFORMATION Procedures and Fees § 20.46 Waiver or reduction of fees. (a) Standard. The Assistant Commissioner...

  1. 21 CFR 20.46 - Waiver or reduction of fees.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... information to the public. An unsupported claim to be doing research for a book or article does not.... The interest of a representative of the news media in using the information for news dissemination... INFORMATION Procedures and Fees § 20.46 Waiver or reduction of fees. (a) Standard. The Assistant Commissioner...

  2. 21 CFR 20.46 - Waiver or reduction of fees.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... information to the public. An unsupported claim to be doing research for a book or article does not.... The interest of a representative of the news media in using the information for news dissemination... INFORMATION Procedures and Fees § 20.46 Waiver or reduction of fees. (a) Standard. The Assistant Commissioner...

  3. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    Expedition 20 Flight Engineer Michael Barratt is helped out of a Russian Search and Rescue helicopter after a two hour helicopter flight from the Soyuz TMA-14 landing site to Kustanay, kazakhstan on Sunday, Oct. 11, 2009. Barratt, Expedition 20 Commander Gennady Padalka, and spaceflight participant Guy Laliberté landed their Soyuz TMA-14 capsule near the town of Arkalyk, Kazakhstan. Padalka and Barratt are returned from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  4. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    NASA Flight Surgeon Ed Powers, left, laughs as Expedition 20 Flight Engineer Michael Barratt talks about how strange, weight and gravity feel when holding a bottle of water shortly after Barratt, Expedition 20 Commander Gennady Padalka, and spaceflight participant Guy Laliberté landed their Soyuz TMA-14 capsule near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  5. A 21st Century Library in a 20th Century Space

    ERIC Educational Resources Information Center

    Graboyes, Alanna S.

    2012-01-01

    The library at George C. Marshall High School in Fairfax County, Virginia, needed an update to better meet the needs of 21st century students. A major renovation was in the works, but head librarian Graboyes wanted to do something to make the library useful and appealing for current students. With careful budgeting and donations of time and money,…

  6. Photoemission study of absorption mechanisms in Bi2.0Sr1.8Ca0.8La0.3Cu2.1O8+δ, BaBiO3, and Nd1.85Ce0.15CuO4

    NASA Astrophysics Data System (ADS)

    Lindberg, P. A. P.; Shen, Z.-X.; Wells, B. O.; Dessau, D. S.; Ellis, W. P.; Borg, A.; Kang, J.-S.; Mitzi, D. B.; Lindau, I.; Spicer, W. E.; Kapitulnik, A.

    1989-11-01

    Photoemission measurements in the constant-final-state (absorption) mode were performed on three different classes of high-temperature superconductors Bi2.0Sr1.8Ca0.8La0.3Cu2.1O8+δ, BaBiO3, and Nd1.85Ce0.15CuO4 using synchrotron radiation from 20 to 200 eV. Absorption signals from all elements but Ce are identified. The results firmly show that the Bi 6s electrons are more delocalized in BaBiO3 than in Bi2.0Sr1.8Ca0.8La0.3Cu2.1O8+δ, in agreement with the results of band-structure calculations. Differences in the absorption signals due to O and Bi excitations between BaBiO3 and Bi2.0Sr1.8Ca0.8La0.3Cu2.1O8+δ are discussed. Delayed absorption onsets attributed to giant resonances (Ba 4d-->4f, La 4d-->4f, and Nd 4d-->4f transitions) are also reported.

  7. P values are only an index to evidence: 20th- vs. 21st-century statistical science.

    PubMed

    Burnham, K P; Anderson, D R

    2014-03-01

    Early statistical methods focused on pre-data probability statements (i.e., data as random variables) such as P values; these are not really inferences nor are P values evidential. Statistical science clung to these principles throughout much of the 20th century as a wide variety of methods were developed for special cases. Looking back, it is clear that the underlying paradigm (i.e., testing and P values) was weak. As Kuhn (1970) suggests, new paradigms have taken the place of earlier ones: this is a goal of good science. New methods have been developed and older methods extended and these allow proper measures of strength of evidence and multimodel inference. It is time to move forward with sound theory and practice for the difficult practical problems that lie ahead. Given data the useful foundation shifts to post-data probability statements such as model probabilities (Akaike weights) or related quantities such as odds ratios and likelihood intervals. These new methods allow formal inference from multiple models in the a prior set. These quantities are properly evidential. The past century was aimed at finding the "best" model and making inferences from it. The goal in the 21st century is to base inference on all the models weighted by their model probabilities (model averaging). Estimates of precision can include model selection uncertainty leading to variances conditional on the model set. The 21st century will be about the quantification of information, proper measures of evidence, and multi-model inference. Nelder (1999:261) concludes, "The most important task before us in developing statistical science is to demolish the P-value culture, which has taken root to a frightening extent in many areas of both pure and applied science and technology".

  8. Developpement D'un Modele Climatique Regional: Fizr Simulation des Conditions de Janvier de la Cote Ouest Nord Americaine

    NASA Astrophysics Data System (ADS)

    Goyette, Stephane

    1995-11-01

    Le sujet de cette these concerne la modelisation numerique du climat regional. L'objectif principal de l'exercice est de developper un modele climatique regional ayant les capacites de simuler des phenomenes de meso-echelle spatiale. Notre domaine d'etude se situe sur la Cote Ouest nord americaine. Ce dernier a retenu notre attention a cause de la complexite du relief et de son controle sur le climat. Les raisons qui motivent cette etude sont multiples: d'une part, nous ne pouvons pas augmenter, en pratique, la faible resolution spatiale des modeles de la circulation generale de l'atmosphere (MCG) sans augmenter a outrance les couts d'integration et, d'autre part, la gestion de l'environnement exige de plus en plus de donnees climatiques regionales determinees avec une meilleure resolution spatiale. Jusqu'alors, les MCG constituaient les modeles les plus estimes pour leurs aptitudes a simuler le climat ainsi que les changements climatiques mondiaux. Toutefois, les phenomenes climatiques de fine echelle echappent encore aux MCG a cause de leur faible resolution spatiale. De plus, les repercussions socio-economiques des modifications possibles des climats sont etroitement liees a des phenomenes imperceptibles par les MCG actuels. Afin de circonvenir certains problemes inherents a la resolution, une approche pratique vise a prendre un domaine spatial limite d'un MCG et a y imbriquer un autre modele numerique possedant, lui, un maillage de haute resolution spatiale. Ce processus d'imbrication implique alors une nouvelle simulation numerique. Cette "retro-simulation" est guidee dans le domaine restreint a partir de pieces d'informations fournies par le MCG et forcee par des mecanismes pris en charge uniquement par le modele imbrique. Ainsi, afin de raffiner la precision spatiale des previsions climatiques de grande echelle, nous developpons ici un modele numerique appele FIZR, permettant d'obtenir de l'information climatique regionale valide a la fine echelle spatiale

  9. 14 CFR 34.20 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... EXHAUST EMISSION REQUIREMENTS FOR TURBINE ENGINE POWERED AIRPLANES Exhaust Emissions (New Aircraft Gas Turbine Engines) § 34.20 Applicability. The provisions of this subpart are applicable to all aircraft gas turbine engines of the classes specified beginning on the dates specified in § 34.21. ...

  10. 14 CFR 34.20 - Applicability.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... EXHAUST EMISSION REQUIREMENTS FOR TURBINE ENGINE POWERED AIRPLANES Exhaust Emissions (New Aircraft Gas Turbine Engines) § 34.20 Applicability. The provisions of this subpart are applicable to all aircraft gas turbine engines of the classes specified beginning on the dates specified in § 34.21. ...

  11. 14 CFR 34.20 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... EXHAUST EMISSION REQUIREMENTS FOR TURBINE ENGINE POWERED AIRPLANES Exhaust Emissions (New Aircraft Gas Turbine Engines) § 34.20 Applicability. The provisions of this subpart are applicable to all aircraft gas turbine engines of the classes specified beginning on the dates specified in § 34.21. ...

  12. 50 CFR 20.22 - Closed seasons.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... PLANTS (CONTINUED) MIGRATORY BIRD HUNTING Taking § 20.22 Closed seasons. No person shall take migratory game birds during the closed season except as provided in part 21 of this chapter. [73 FR 65951, Nov. 5...

  13. Encapsulating Moral Dilemma through Short Story: Challenging Pre-Service Teachers to Critically Think about the Student/Teacher Personality and Leadership Dynamic

    ERIC Educational Resources Information Center

    Lennon, Sean M.

    2007-01-01

    Pre-service teachers and education students in three different classes (N = 53) were directed to read a short story by Mark Twain titled "Heaven or Hell?" written within a compilation of short stories late in his career. The story, "Heaven or Hell?" illustrates a koan, or an unanswerable moral or ethical dilemma. The students,…

  14. 22 CFR 228.20 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Relations AGENCY FOR INTERNATIONAL DEVELOPMENT RULES ON SOURCE, ORIGIN AND NATIONALITY FOR COMMODITIES AND... Financing § 228.20 Purpose. Sections 228.21 through 228.25 set forth the rules governing the eligibility of commodity-related services, both delivery services and incidental services, for USAID financing. These rules...

  15. 21 CFR 189.155 - Monochloroacetic acid.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... monochloroacetic acid in food are in sections 20.067-20.072 of the “Official Methods of Analysis of the Association... 21 Food and Drugs 3 2014-04-01 2014-04-01 false Monochloroacetic acid. 189.155 Section 189.155 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED...

  16. 18,21-Anhydroaldosterone and derivatives.

    PubMed

    Harnik, M; Kashman, Y; Cojocaru, M; Lewicka, S; Vecsei, P

    1989-07-01

    18,21-Anhydroaldosterone 8, 18,21-anhydro-19-noraldosterone 9, and 3 alpha, 5 beta-tetrahydro-18,21-anhydro-19-noraldosterone 13, which may be present in acid-processed urine, were prepared by cleaving their 20-ketal derivatives 2, 3, and 12 with hot mineral acid. Compounds 8 and 9 were also made by direct dehydration of aldosterone 5 and 19-noraldosterone 10 in good yield. The reverse ring opening of 8 to 5 could be carried out in moderate yield with an acetic acid-acetic anhydride-perchloric acid mixture, while an analogous ring opening of 9 gave only a poor yield of 10.

  17. A strong enrichment of potentially toxic elements (PTEs) in Nord-Trøndelag (central Norway) forest soil.

    PubMed

    Reimann, C; Fabian, K; Schilling, J; Roberts, D; Englmaier, P

    2015-12-01

    Analysis of soil C and O horizon samples in a recent regional geochemical survey of Nord-Trøndelag, central Norway (752 sample sites covering 25,000 km2), identified a strong enrichment of several potentially toxic elements (PTEs) in the O horizon. Of 53 elements analysed in both materials, Cd concentrations are, on average, 17 times higher in the O horizon than in the C horizon and other PTEs such as Ag (11-fold), Hg (10-fold), Sb (8-fold), Pb (4-fold) and Sn (2-fold) are all strongly enriched relative to the C horizon. Geochemical maps of the survey area do not reflect an impact from local or distant anthropogenic contamination sources in the data for O horizon soil samples. The higher concentrations of PTEs in the O horizon are the result of the interaction of the underlying geology, the vegetation zone and type, and climatic effects. Based on the general accordance with existing data from earlier surveys in other parts of northern Europe, the presence of a location-independent, superordinate natural trend towards enrichment of these elements in the O horizon relative to the C horizon soil is indicated. The results imply that the O and C horizons of soils are different geochemical entities and that their respective compositions are controlled by different processes. Local mineral soil analyses (or published data for the chemical composition of the average continental crust) cannot be used to provide a geochemical background for surface soil. At the regional scale used here surface soil chemistry is still dominated by natural sources and processes. Copyright © 2015 Elsevier B.V. All rights reserved.

  18. 21 CFR 177.1550 - Perfluorocarbon resins.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... may not be used with the optional component, lithium polysilicate, mentioned in paragraph (b)(4) of... substances Limitations Lithium polysilicate containing not more than 20 weight percent silica, not more than 2.1 percent lithium oxide and having a maximum mole ratio of Si02/Li20 of 8.5 to 1 For use only as a...

  19. 21 CFR 177.1550 - Perfluorocarbon resins.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... may not be used with the optional component, lithium polysilicate, mentioned in paragraph (b)(4) of... substances Limitations Lithium polysilicate containing not more than 20 weight percent silica, not more than 2.1 percent lithium oxide and having a maximum mole ratio of Si02/Li20 of 8.5 to 1 For use only as a...

  20. 21 CFR 177.1550 - Perfluorocarbon resins.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... may not be used with the optional component, lithium polysilicate, mentioned in paragraph (b)(4) of... substances Limitations Lithium polysilicate containing not more than 20 weight percent silica, not more than 2.1 percent lithium oxide and having a maximum mole ratio of Si02/Li20 of 8.5 to 1 For use only as a...

  1. 21 CFR 177.1550 - Perfluorocarbon resins.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... may not be used with the optional component, lithium polysilicate, mentioned in paragraph (b)(4) of... substances Limitations Lithium polysilicate containing not more than 20 weight percent silica, not more than 2.1 percent lithium oxide and having a maximum mole ratio of Si02/Li20 of 8.5 to 1 For use only as a...

  2. 21 CFR 170.20 - General principles for evaluating the safety of food additives.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... food additives. 170.20 Section 170.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES Food Additive Safety § 170.20 General principles for evaluating the safety of food additives. (a) In reaching a...

  3. 21 CFR 170.20 - General principles for evaluating the safety of food additives.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... food additives. 170.20 Section 170.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES Food Additive Safety § 170.20 General principles for evaluating the safety of food additives. (a) In reaching a...

  4. 21 CFR 170.20 - General principles for evaluating the safety of food additives.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... food additives. 170.20 Section 170.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES Food Additive Safety § 170.20 General principles for evaluating the safety of food additives. (a) In reaching a...

  5. 21 CFR 170.20 - General principles for evaluating the safety of food additives.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... food additives. 170.20 Section 170.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES Food Additive Safety § 170.20 General principles for evaluating the safety of food additives. (a) In reaching a...

  6. 21 CFR 570.20 - General principles for evaluating the safety of food additives.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... food additives. 570.20 Section 570.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES Food Additive Safety § 570.20 General principles for evaluating the safety of food additives. (a) In reaching a...

  7. 21 CFR 570.20 - General principles for evaluating the safety of food additives.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... food additives. 570.20 Section 570.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES Food Additive Safety § 570.20 General principles for evaluating the safety of food additives. (a) In reaching a...

  8. 21 CFR 570.20 - General principles for evaluating the safety of food additives.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... food additives. 570.20 Section 570.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS FOOD ADDITIVES Food Additive Safety § 570.20 General principles for evaluating the safety of food additives. (a) In reaching a...

  9. 21 CFR 170.20 - General principles for evaluating the safety of food additives.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... food additives. 170.20 Section 170.20 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD ADDITIVES Food Additive Safety § 170.20 General principles for evaluating the safety of food additives. (a) In reaching a decision on any petition filed under section 409...

  10. 24Mg(p, α) 21Na reaction study for spectroscopy of 21Na

    DOE PAGES

    Cha, S. M.; Chae, K. Y.; Kim, A.; ...

    2015-11-03

    The Mg-24(p, alpha)Na-21 reaction was measured at the Holifield Radioactive Ion Beam Facility at Oak Ridge National Laboratory in order to better constrain the spins and parities of the energy levels in Na-21 for the astrophysically important F-17(alpha, p)Ne-20 reaction rate calculation. 31-MeV proton beams from the 25-MV tandem accelerator and enriched Mg-24 solid targets were used. When recoiling He-4 particles from the Mg-24(p, alpha)Na-21 reaction we used a highly segmented silicon detector array to detect them; it measured the yields of He-4 particles over a range of angles simultaneously. A observed a new level at 6661 ± 5 keVmore » in the present work. The extracted angular distributions for the first four levels of Na-21 and the results from distorted wave Born approximation (DWBA) calculations were compared to verify and extract the angular momentum transfer.« less

  11. Has life satisfaction in Norway increased over a 20-year period? Exploring age and gender differences in a prospective longitudinal study, HUNT.

    PubMed

    Lysberg, Frode; Gjerstad, PåL; Småstuen, Milada Cvancarova; Innstrand, Siw Tone; Høie, Magnhild Mjåvatn; Arild Espnes, Geir

    2018-02-01

    The aim of the present study was to investigate the change in overall life satisfaction for different age groups and between genders over a 20-year period. Data from 1984 to 2008 were extracted from a large prospective longitudinal health study of Nord-Trøndelag (HUNT), Norway. The study included more than 176,000 participants ranging from 20 to 70+ years of age. Data were analysed using logistic regression and adjusted for gender. The analyses revealed an increase in life satisfaction for all age groups from 1984-1986 (HUNT 1) to 1995-1997 (HUNT 2), with the highest levels being reached at 2006-2008 (HUNT 3). For all age groups, the data showed an increase of about 20% for the period from 1984-1986 (HUNT 1) to 1995-1997 (HUNT 2). From 1995-1997 (HUNT 2) to 2006-2008 (HUNT 3), the increase in overall life satisfaction was 16% for the younger age groups, and about 32% for the older age groups (40-69 and 70+ years). Women's scores for overall life satisfaction were higher for nearly all age groups when compared to men using HUNT 3 as a reference. These findings suggest an increase in life satisfaction for all age groups from 1984 to 2008, especially for the older age group (40-69 and 70+ years). The data indicate that women score higher on life satisfaction for most age groups as compared to men.

  12. USH1K, a novel locus for type I Usher syndrome, maps to chromosome 10p11.21-q21.1.

    PubMed

    Jaworek, Thomas J; Bhatti, Rashid; Latief, Noreen; Khan, Shaheen N; Riazuddin, Saima; Ahmed, Zubair M

    2012-10-01

    We ascertained two large Pakistani consanguineous families (PKDF231 and PKDF608) segregating profound hearing loss, vestibular dysfunction, and retinitis pigmentosa; the defining features of Usher syndrome type 1 (USH1). To date, seven USH1 loci have been reported. Here, we map a novel locus, USH1K, on chromosome 10p11.21-q21.1. In family PKDF231, we performed a genome-wide linkage screen and found a region of homozygosity shared among the affected individuals at chromosome 10p11.21-q21.1. Meiotic recombination events in family PKDF231 define a critical interval of 11.74 cM (20.20 Mb) bounded by markers D10S1780 (63.83 cM) and D10S546 (75.57 cM). Affected individuals of family PKDF608 were also homozygous for chromosome 10p11.21-q21.1-linked STR markers. Of the 85 genes within the linkage interval, PCDH15, GJD4, FZD4, RET and LRRC18 were sequenced in both families, but no potential pathogenic mutation was identified. The USH1K locus overlaps the non-syndromic deafness locus DFNB33 raising the possibility that the two disorders may be caused by allelic mutations.

  13. On the Relative Influences of Different Ocean Basin Sea Surface Temperature Anomalies on Southern African Rainfall in 20th and 21st Century GCM Simulations

    NASA Astrophysics Data System (ADS)

    Lickley, M.; Solomon, S.

    2017-12-01

    Southern Africa rainfall (SAR) is generally projected to decrease during the 21st century as a result of climate change, though there is some disagreement regarding the location and magnitude of this reduction in General Circulation Models (GCMs). Here we examine the robustness of the rainfall response to sea surface temperature (SST) anomalies. Previous work argues that warmer SSTs in the Indian Ocean suppress SAR. Other studies argue that El Niños lead to suppressed SAR. We examine the SAR response to SST anomalies in the Indian Ocean, Atlantic Ocean and ENSO 3.4 region both in observations and in two large ensembles of GCMs run over the 20th and 21st century. We find that ENSO SSTs are most correlated with SAR, while correlations between SAR and the Indian Ocean are dominated by their respective responses to ENSO. This relationship appears to persist under a warming background state.

  14. Project WET Curriculum and Activity Guide 2.0

    ERIC Educational Resources Information Center

    Project WET Foundation, 2011

    2011-01-01

    The "Project WET Curriculum and Activity Guide 2.0" continues Project WET's dedication to 21st-century, cutting-edge water education. Now in full color, Guide 2.0 offers new activities on topics such as National Parks and storm water, fully revised and updated activities from the original Guide and the very best activities gathered from all of…

  15. Paternal and maternal alcohol abuse and offspring mental distress in the general population: the Nord-Trøndelag health study

    PubMed Central

    2012-01-01

    Background The degree to which parental alcohol abuse is a risk factor for offspring mental distress is unclear, due to conflicting results of previous research. The inconsistencies in previous findings may be related to sample characteristics and lack of control of confounding or moderating factors. One such factor may be the gender of the abusing parent. Also, other factors, such as parental mental health, divorce, adolescent social network, school functioning or self-esteem, may impact the outcome. This study examines the impact of maternal and paternal alcohol abuse on adolescent mental distress, including potentially confounding, mediating or moderating effects of various variables. Methods Data from the Nord-Trøndelag Health Study (HUNT), a Norwegian population based health survey, from 4012 offspring and their parents were analyzed. Parental alcohol abuse was measured by numerical consumption indicators and CAGE, whereas offspring mental distress was measured by SCL-5, an abbreviated instrument tapping symptoms of anxiety and depression. Statistical method was analysis of variance. Results Maternal alcohol abuse was related to offspring mental distress, whereas no effect could be shown of paternal alcohol abuse. Effects of maternal alcohol abuse was partly mediated by parental mental distress, offspring social network and school functioning. However, all effects were relatively small. Conclusions The results indicate graver consequences for offspring of alcohol abusing mothers compared to offspring of alcohol abusing fathers. However, small effect sizes suggest that adolescent offspring of alcohol abusing parents in general manage quite well. PMID:22708789

  16. Risk and protective factors for psychological distress among adolescents: a family study in the Nord-Trøndelag Health Study.

    PubMed

    Myklestad, Ingri; Røysamb, Espen; Tambs, Kristian

    2012-05-01

    The study aimed to investigate potential adolescent and parental psychosocial risk and protective factors for psychological distress among adolescents and, in addition, to examine potential gender and age differences in the effects of risk factors on adolescent psychological distress. Data were collected among 8,984 Norwegian adolescents (13-19 years) and their parents in the Nord-Trøndelag Health Study (HUNT). The outcome measure was psychological distress (SCL-5). Bivariate regression analysis with generalized estimating equation (GEE) model showed that all parental self-reported variables (mental distress, substance use, social network, economic problems, unemployment and family structure) and adolescents' self-reported variables (leisure activities, social support from friends, school-related problems and substance use) were significantly associated with psychological distress among adolescents. Results revealed that in a multiple regression analysis with a GEE model, adolescent psychosocial variables, specifically academic-related problems and being bullied at school, emerged as the strongest predictors of psychological distress among adolescents after controlling for age, gender, and all parental and adolescent variables. The following psychosocial risk factors were significantly more important for girl's psychological distress compared to boys: problems with academic achievement, conduct problems in school, frequency of being drunk, smoking, dissatisfaction in school, living alone and seen parents being drunk. Academic achievement and being bullied at school were the psychosocial factors most strongly associated with psychological distress among adolescents. Parental factors had an indirect effect on adolescent psychological distress, through adolescents' psychosocial factors.

  17. Utilisation d'images aeroportees a tres haute resolution spatiale pour l'estimation de la vigueur des peuplements forestiers du nord-ouest du Nouveau-Brunswick

    NASA Astrophysics Data System (ADS)

    Louis, Ognel Pierre

    Le but de cette etude est de developper un outil permettant d'estimer le niveau de risque de perte de vigueur des peuplements forestiers de la region de Gounamitz au nord-ouest du Nouveau-Brunswick via des donnees d'inventaires forestiers et des donnees de teledetection. Pour ce faire, un marteloscope de 100m x 100m et 20 parcelles d'echantillonnages ont ete delimites. A l'interieur de ces derniers, le niveau de risque de perte de vigueur des arbres ayant un DHP superieur ou egal a 9 cm a ete determine. Afin de caracteriser le risque de perte de vigueur des arbres, leurs positions spatiales ont ete repertoriees a partir d'un GPS en tenant compte des defauts au niveau des tiges. Pour mener a bien ce travail, les indices de vegetation et de textures et les bandes spectrales de l'image aeroportee ont ete extraits et consideres comme variables independantes. Le niveau de risque de perte de vigueur obtenu par espece d'arbre a travers les inventaires forestiers a ete considere comme variable dependante. En vue d'obtenir la superficie des peuplements forestiers de la region d'etude, une classification dirigee des images a partir de l'algorithme maximum de vraisemblance a ete effectuee. Le niveau de risque de perte de vigueur par type d'arbre a ensuite ete estime a l'aide des reseaux de neurones en utilisant un reseau dit perceptron multicouches. Il s'agit d'un modele de reseau de neurones compose de : 11 neurones sur la couche d'entree, correspondant aux variables independantes, 35 neurones sur la couche cachee et 4 neurones sur la couche de sortie. La prediction a partir des reseaux de neurones produit une matrice de confusion qui permet d'obtenir des mesures quantitatives d'estimation, notamment un pourcentage de classification globale de 91,7% pour la prediction du risque de perte de vigueur du peuplement de resineux et de 89,7% pour celui du peuplement de feuillus. L'evaluation de la performance des reseaux de neurones fournit une valeur de MSE globale de 0,04, et une

  18. Transformations in Air Transportation Systems For the 21st Century

    NASA Technical Reports Server (NTRS)

    Holmes, Bruce J.

    2004-01-01

    Globally, our transportation systems face increasingly discomforting realities: certain of the legacy air and ground infrastructures of the 20th century will not satisfy our 21st century mobility needs. The consequence of inaction is diminished quality of life and economic opportunity for those nations unable to transform from the 20th to 21st century systems. Clearly, new thinking is required regarding business models that cater to consumers value of time, airspace architectures that enable those new business models, and technology strategies for innovating at the system-of-networks level. This lecture proposes a structured way of thinking about transformation from the legacy systems of the 20th century toward new systems for the 21st century. The comparison and contrast between the legacy systems of the 20th century and the transformed systems of the 21st century provides insights into the structure of transformation of air transportation. Where the legacy systems tend to be analog (versus digital), centralized (versus distributed), and scheduled (versus on-demand) for example, transformed 21st century systems become capable of scalability through technological, business, and policy innovations. Where air mobility in our legacy systems of the 20th century brought economic opportunity and quality of life to large service markets, transformed air mobility of the 21st century becomes more equitable available to ever-thinner and widely distributed populations. Several technological developments in the traditional aircraft disciplines as well as in communication, navigation, surveillance and information systems create new foundations for 21st thinking about air transportation. One of the technological developments of importance arises from complexity science and modern network theory. Scale-free (i.e., scalable) networks represent a promising concept space for modeling airspace system architectures, and for assessing network performance in terms of robustness

  19. European Energy Security and Nord Stream: A Case Study of the Nord Stream Pipeline, Its Opportunities and Risks for Europe, and Its Impact on European Energy Security

    DTIC Science & Technology

    2011-06-01

    Union is willing to reduce its greenhouse gas emissions by 20% by 2020 and increase the overall share of renewables by 20% by 2020,4 fossil fuels will...Europe‘s climate change opportunity.‖ It addresses two key targets—the reduction of 20% of all greenhouse gas emissions by 2020 and a 20% share of the...fuels are accountable for the biggest part of greenhouse gas emissions , and invest in new CO2- 88

  20. 21 CFR 20.55 - Indexing trade secrets and confidential commercial or financial information.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Indexing trade secrets and confidential commercial... secrets and confidential commercial or financial information. Whenever the Food and Drug Administration... exempt from public disclosure as trade secret or confidential commercial or financial data and...

  1. 21 CFR 20.55 - Indexing trade secrets and confidential commercial or financial information.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 1 2014-04-01 2014-04-01 false Indexing trade secrets and confidential commercial... secrets and confidential commercial or financial information. Whenever the Food and Drug Administration... exempt from public disclosure as trade secret or confidential commercial or financial data and...

  2. 21 CFR 20.55 - Indexing trade secrets and confidential commercial or financial information.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Indexing trade secrets and confidential commercial... secrets and confidential commercial or financial information. Whenever the Food and Drug Administration... exempt from public disclosure as trade secret or confidential commercial or financial data and...

  3. 21 CFR 20.55 - Indexing trade secrets and confidential commercial or financial information.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Indexing trade secrets and confidential commercial... secrets and confidential commercial or financial information. Whenever the Food and Drug Administration... exempt from public disclosure as trade secret or confidential commercial or financial data and...

  4. 21 CFR 20.55 - Indexing trade secrets and confidential commercial or financial information.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Indexing trade secrets and confidential commercial... secrets and confidential commercial or financial information. Whenever the Food and Drug Administration... exempt from public disclosure as trade secret or confidential commercial or financial data and...

  5. Upregulation of Interleukin 21 and Interleukin 21 Receptor in Patients with Dermatomyositis and Polymyositis.

    PubMed

    Liu, Tao; Hou, Ying; Dai, Ting-Jun; Yan, Chuan-Zhu

    2017-09-05

    The immunopathologic mechanism underlying dermatomyositis (DM) and polymyositis (PM) remains poorly understood. Many cytokines play a pathogenic role in DM and PM. Interleukin 21 (IL-21) has a pleiotropic effect on inflammation regulation. This study aimed to detect the serum IL-21 level and investigate the expression of IL-21 and IL-21 receptor (IL-21R) in muscle tissues of patients with DM and PM. Biopsied muscle samples were obtained from 11 patients with DM, 12 with PM, and six controls; mRNA levels of IL-21 and IL-21R were analyzed by real-time quantitative reverse transcription-polymerase chain reaction; and immunohistochemical staining was used to evaluate the protein expression of IL-21 and IL-21R. Serum samples were obtained from 36 patients with DM, 19 with PM, and 20 healthy controls. The serum IL-21 level was detected by enzyme-linked immunosorbent assay. The expression of IL-21 was upregulated in patients with DM and PM. The IL-21 mRNA level was significantly increased in muscle tissues of patients with DM and PM (DM vs. control, P= 0.001; PM vs. control, P= 0.001), whereas IL-21R mRNA level in patients with DM/PM was not statistically different from that of healthy controls. Immunohistochemical staining showed both IL-21 and IL-21R were significantly expressed in the inflammatory cells in muscle tissues of patients with DM and PM. The serum IL-21 level was also significantly higher in patients with DM/PM than in controls (DM vs. control, 49.12 [45.28, 60.07] pg/ml vs. 42.54 [38.69, 48.85] pg/ml, P= 0.001; PM vs. control, 50.77 [44.19, 60.62] pg/ml vs. 42.54 [38.69, 48.85] pg/ml, P= 0.005). IL-21 expression is upregulated in patients with DM and PM in both muscle tissue and serum. In addition, IL-21R protein is highly expressed in affected muscle tissues of patients with DM and PM. IL-21 may play a pathogenic role through IL-21R in patients with DM and PM.

  6. 16 CFR 1115.20 - Voluntary remedial actions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... following week's agenda. All comments must be in writing, and final written comments must be submitted at... may subject a violator to civil and/or criminal penalties under sections 20 and 21 of the CPSA (15 U.S...

  7. 16 CFR 1115.20 - Voluntary remedial actions.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... following week's agenda. All comments must be in writing, and final written comments must be submitted at... may subject a violator to civil and/or criminal penalties under sections 20 and 21 of the CPSA (15 U.S...

  8. 16 CFR 1115.20 - Voluntary remedial actions.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... following week's agenda. All comments must be in writing, and final written comments must be submitted at... may subject a violator to civil and/or criminal penalties under sections 20 and 21 of the CPSA (15 U.S...

  9. 24 CFR 8.20 - General requirement concerning program accessibility.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false General requirement concerning program accessibility. 8.20 Section 8.20 Housing and Urban Development Office of the Secretary, Department... requirement concerning program accessibility. Except as otherwise provided in §§ 8.21(c)(1), 8.24(a), 8.25...

  10. 10 CFR 765.21 - Procedures for processing reimbursement claims.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Section 765.21 Energy DEPARTMENT OF ENERGY REIMBURSEMENT FOR COSTS OF REMEDIAL ACTION AT ACTIVE URANIUM AND THORIUM PROCESSING SITES Procedures for Submitting and Processing Reimbursement Claims § 765.21... specified in § 765.20(g) to determine the completeness of each claim. Payments from the Fund to active...

  11. Weather, Climate, Web 2.0: 21st Century Students Speak Climate Science Well

    ERIC Educational Resources Information Center

    Sundberg, Cheryl White; Kennedy, Teresa; Odell, Michael R. L.

    2013-01-01

    Problem-based learning (PBL) and inquiry learning (IL) employ extensive scaffolding that results in cognitive load reduction and allows students to learn in complex domains. Hybrid teacher professional development models (PDM) using 21st century social collaboration tools embedding PBL and IL shows promise as a systemic approach for increasing…

  12. 21 CFR 20.110 - Data and information about Food and Drug Administration employees.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 1 2011-04-01 2011-04-01 false Data and information about Food and Drug... Data and information about Food and Drug Administration employees. (a) The name, title, grade, position... are available for public disclosure. The home address and home telephone number of any such employee...

  13. 21 CFR 20.110 - Data and information about Food and Drug Administration employees.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 1 2013-04-01 2013-04-01 false Data and information about Food and Drug... Data and information about Food and Drug Administration employees. (a) The name, title, grade, position... are available for public disclosure. The home address and home telephone number of any such employee...

  14. 21 CFR 20.110 - Data and information about Food and Drug Administration employees.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 1 2012-04-01 2012-04-01 false Data and information about Food and Drug... Data and information about Food and Drug Administration employees. (a) The name, title, grade, position... are available for public disclosure. The home address and home telephone number of any such employee...

  15. Reading & Accountability: Improving 21st Century Schools. Hearing before the Committee on Education and the Workforce. House of Representatives, One Hundred Seventh Congress, First Session (Marietta, Georgia, February 20, 2001).

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Committee on Education and the Workforce.

    A hearing, held in Marietta, Georgia, on February 20, 2001, before the Committee on Education and the Workforce, House of Representatives, 107th Congress, dealt with reading and accountability and improving 21st century schools. These proceedings of the hearing contain the following: Statement of Congressman Bob Barr, 7th District of Georgia, U.S.…

  16. 21 CFR 20.3 - Certification and authentication of Food and Drug Administration records.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Certification and authentication of Food and Drug... authentication of Food and Drug Administration records. (a) Upon request, the Food and Drug Administration will... or for authentication of records shall be sent in writing to the Freedom of Information Staff (HFI-35...

  17. Inheritance of a Balanced t(12;20)(q24.33;p12.2) and Unbalanced der(13)t(7;13)(p21.3;q33.2) from a Maternally Derived Double Balanced Translocation Carrier.

    PubMed

    Peterson, Jess F; Geddes, Gabrielle C; Basel, Donald G; Schippman, Dana; Grignon, John W; vanTuinen, Peter; Kappes, Ulrike P

    2018-03-01

    We report a 4-month-old male proband with a history of prominent forehead, hypertelorism, ear abnormalities, micrognathia, hypospadias, and multiple cardiac abnormalities. Initial microarray analysis detected a concurrent 7p21.3-p22.3 duplication and 13q33.2-q34 deletion indicating an unbalanced rearrangement. However, subsequent conventional cytogenetic studies only revealed what appeared to be a balanced t(12;20)(q24.33;p12.2). Fluorescence in situ hybridization (FISH) using chromosome-specific subtelomere probes confirmed the presence of an unbalanced der(13)t(7;13)(p21.3;q33.2) and balanced t(12;20)(q24.33;p12.2), both of maternal origin. In addition to our unique clinical findings, this case highlights the benefits and limitations of both conventional cytogenetic studies and microarray analysis and how FISH complements each methodology.

  18. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    Russian Search and Rescue force vehicles follow the Soyuz TMA-14 spacecraft as it lands with Expedition 20 Commander Gennady Padalka, Flight Engineer Michael Barratt, and spaceflight participant Guy Laliberté near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  19. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    A Russian Search and Rescue force helicopter flies around the Soyuz TMA-14 spacecraft as it lands with Expedition 20 Commander Gennady Padalka, Flight Engineer Michael Barratt, and spaceflight participant Guy Laliberté near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)

  20. Expedition 20 Landing

    NASA Image and Video Library

    2009-10-10

    Russian Search and Rescue force vehicles and helicopter arrive within seconds of the Soyuz TMA-14 spacecraft landing with Expedition 20 Commander Gennady Padalka, Flight Engineer Michael Barratt, and spaceflight participant Guy Laliberté near the town of Arkalyk, Kazakhstan on Sunday, Oct. 11, 2009. Padalka and Barratt are returning from six months onboard the International Space Station, along with Laliberté who arrived at the station on Oct. 2 with Expedition 21 Flight Engineers Jeff Williams and Maxim Suraev aboard the Soyuz TMA-16 spacecraft. Photo Credit: (NASA/Bill Ingalls)