Key Topics for High-Lift Research: A Joint Wind Tunnel/Flight Test Approach

NASA Technical Reports Server (NTRS)

Fisher, David; Thomas, Flint O.; Nelson, Robert C.

1996-01-01

Future high-lift systems must achieve improved aerodynamic performance with simpler designs that involve fewer elements and reduced maintenance costs. To expeditiously achieve this, reliable CFD design tools are required. The development of useful CFD-based design tools for high lift systems requires increased attention to unresolved flow physics issues. The complex flow field over any multi-element airfoil may be broken down into certain generic component flows which are termed high-lift building block flows. In this report a broad spectrum of key flow field physics issues relevant to the design of improved high lift systems are considered. It is demonstrated that in-flight experiments utilizing the NASA Dryden Flight Test Fixture (which is essentially an instrumented ventral fin) carried on an F-15B support aircraft can provide a novel and cost effective method by which both Reynolds and Mach number effects associated with specific high lift building block flows can be investigated. These in-flight high lift building block flow experiments are most effective when performed in conjunction with coordinated ground based wind tunnel experiments in low speed facilities. For illustrative purposes three specific examples of in-flight high lift building block flow experiments capable of yielding a high payoff are described. The report concludes with a description of a joint wind tunnel/flight test approach to high lift aerodynamics research.

Technical advances in flow cytometry-based diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria

PubMed Central

Correia, Rodolfo Patussi; Bento, Laiz Cameirão; Bortolucci, Ana Carolina Apelle; Alexandre, Anderson Marega; Vaz, Andressa da Costa; Schimidell, Daniela; Pedro, Eduardo de Carvalho; Perin, Fabricio Simões; Nozawa, Sonia Tsukasa; Mendes, Cláudio Ernesto Albers; Barroso, Rodrigo de Souza; Bacal, Nydia Strachman

2016-01-01

ABSTRACT Objective: To discuss the implementation of technical advances in laboratory diagnosis and monitoring of paroxysmal nocturnal hemoglobinuria for validation of high-sensitivity flow cytometry protocols. Methods: A retrospective study based on analysis of laboratory data from 745 patient samples submitted to flow cytometry for diagnosis and/or monitoring of paroxysmal nocturnal hemoglobinuria. Results: Implementation of technical advances reduced test costs and improved flow cytometry resolution for paroxysmal nocturnal hemoglobinuria clone detection. Conclusion: High-sensitivity flow cytometry allowed more sensitive determination of paroxysmal nocturnal hemoglobinuria clone type and size, particularly in samples with small clones. PMID:27759825

Base flow of streams in the outcrop area of southeastern sand aquifer, South Carolina, Georgia, Alabama, and Mississippi

USGS Publications Warehouse

Stricker, Virginia

1983-01-01

The base flow component of streamflow was separated from hydrographs for unregulated streams in the Cretaceous and Tertiary clastic outcrop area of South Carolina, Georgia, Alabama, and Mississippi. The base flow values are used in estimating recharge to the sand aquifer. Relations developed between mean annual base flow and stream discharge at the 60- and 65-percent streamflow duration point can be used to approximate mean annual base flow in lieu of hydrograph separation methods for base flows above 10 cu ft/s. Base flow recession curves were used to derive estimates of hydraulic diffusivity of the aquifer which was converted to transmissivity using estimated specific yield. These base-flow-derived transmissivities are in general agreement with transmissivities derived from well data. The shape of flow duration curves of streams is affected by the lithology of the Coastal Plain sediments. Steep flow duration curves appear to be associated with basins underlain by clay or chalk where a low percentage of the discharge is base flow while flatter curves appear to be associated with basins underlain by sand and gravel where a high percentage of the discharge is base flow. (USGS)

Structure and shale gas production patterns from eastern Kentucky field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shumaker, R.C.

Computer-derived subsurface structure, isopach, and gas-flow maps, based on 4000 drillers logs, have been generated for eastern Kentucky under a project sponsored by the Gas Research Institute. Structure maps show low-relief flextures related to basement structure. Some structures have been mapped at the surface, others have not. Highest final open-flow (fof) of shale gas from wells in Martin County follow a structural low between (basement) anticlines. From there, elevated gas flows (fof) extend westward along the Warfield monocline to Floyd County where the high flow (fof) trend extends southward along the Floyd County channel. In Knott County, the number ofmore » wells with high gas flow (fof) decreases abruptly. The center of highest gas flow (fof) in Floyd County spreads eastward to Pike County, forming a triangular shaped area of high production (fof). The center of highest gas flow (fof) is in an area where possible (basement) structure trends intersect and where low-relief surface folds (probably detached structure) were mapped and shown on the 1922 version of the Floyd County structure map. Modern regional maps, based on geophysical logs from widely spaced wells, do not define the low-relief structures that have been useful in predicting gas flow trends. Detailed maps based on drillers logs can be misleading unless carefully edited. Comparative analysis of high gas flows (fof) and 10-year cumulative production figures in a small area confirms that there is a relationship between gas flow (fof) values and long-term cumulative production.« less

Large-Eddy Simulation of the Base Flow of a Cylindrical Space Vehicle Configuration

NASA Astrophysics Data System (ADS)

Meiß, J.-H.; Schröder, W.

2009-01-01

A Large-Eddy Simulation (LES) is performed out to in- vestigate high Reynolds number base flow of an axisymmetric rocket-like configuration having an underex- panded nozzle flow. The subsonic base region of low pressure levels is characterized and bounded by the interaction of the freestream of Mach 5.3 and the wide plume of the hot exhaust jet of Mach 3.8. An analysis of the base flow shows that the system of base area vortices determines the highly time-dependent pressure distribution and causes an upstream convection of hot exhaust gas. A comparison of the results with experiments conducted at the German Aerospace Center (DLR) Cologne shows good agreement. The investigation is part of the German RESPACE Pro- gram, which focuses on Key Technologies for Reusable Space Systems.

Flow field design and optimization based on the mass transport polarization regulation in a flow-through type vanadium flow battery

NASA Astrophysics Data System (ADS)

Zheng, Qiong; Xing, Feng; Li, Xianfeng; Ning, Guiling; Zhang, Huamin

2016-08-01

Vanadium flow battery holds great promise for use in large scale energy storage applications. However, the power density is relatively low, leading to significant increase in the system cost. Apart from the kinetic and electronic conductivity improvement, the mass transport enhancement is also necessary to further increase the power density and reduce the system cost. To better understand the mass transport limitations, in the research, the space-varying and time-varying characteristic of the mass transport polarization is investigated based on the analysis of the flow velocity and reactant concentration in the bulk electrolyte by modeling. The result demonstrates that the varying characteristic of mass transport polarization is more obvious at high SoC or high current densities. To soften the adverse impact of the mass transport polarization, a new rectangular plug flow battery with a plug flow and short flow path is designed and optimized based on the mass transport polarization regulation (reducing the mass transport polarization and improving its uniformity of distribution). The regulation strategy of mass transport polarization is practical for the performance improvement in VFBs, especially for high power density VFBs. The findings in the research are also applicable for other flow batteries and instructive for practical use.

Fifth Graders' Flow Experience in a Digital Game-Based Science Learning Environment

ERIC Educational Resources Information Center

Zheng, Meixun; Spires, Hiller A.

2014-01-01

This mixed methods study examined 73 5th graders' flow experience in a game-based science learning environment using two gameplay approaches (solo and collaborative gameplay). Both survey and focus group interview findings revealed that students had high flow experience; however, there were no flow experience differences that were contingent upon…

Flow theory – goal orientation theory: positive experience is related to athlete’s goal orientation

PubMed Central

Stavrou, Nektarios A. M.; Psychountaki, Maria; Georgiadis, Emmanouil; Karteroliotis, Konstantinos; Zervas, Yannis

2015-01-01

The main purpose of this study was to examine the relationship between flow experience and goal orientation theory, as well as, the differences in flow experience based on the orthogonal model of goal orientation theory. Two hundred and seventy eight athletes completed the Task and Ego Orientation Sport Questionnaire based on how they usually feel. The challenge and skills ratings were completed 1 h before the competition, based on how they felt at the exact time of answering. In the following, the Flow State Scale-2 was completed up to 30 min after the competition they just participated, along with the challenge-skill ratings, based on how athletes felt during the competition. The results indicated that the athletes’ task orientation may be an important factor for attaining flow in competitive sport, feeling more skillful and estimating the upcoming competition as challenging, while low ego and low task oriented athletes lack these elements, which are important for them to get into flow. Additionally, not the level of task and ego orientation per se, but the balance between athletes’ goal orientation preferences seems important for the formation of flow experience, indicating that high task – high ego and high task – low ego athletes are experiencing the most positive mental state. PMID:26500577

Debris flow initiation by runoff in a recently burned basin: Is grain-by-grain sediment bulking or en masse failure to blame?

NASA Astrophysics Data System (ADS)

McGuire, Luke A.; Rengers, Francis K.; Kean, Jason W.; Staley, Dennis M.

2017-07-01

Postwildfire debris flows are frequently triggered by runoff following high-intensity rainfall, but the physical mechanisms by which water-dominated flows transition to debris flows are poorly understood relative to debris flow initiation from shallow landslides. In this study, we combined a numerical model with high-resolution hydrologic and geomorphic data sets to test two different hypotheses for debris flow initiation during a rainfall event that produced numerous debris flows within a recently burned drainage basin. Based on simulations, large volumes of sediment eroded from the hillslopes were redeposited within the channel network throughout the storm, leading to the initiation of numerous debris flows as a result of the mass failure of sediment dams that built up within the channel. More generally, results provide a quantitative framework for assessing the potential of runoff-generated debris flows based on sediment supply and hydrologic conditions.

Debris flow initiation by runoff in a recently burned basin: Is grain-by-grain sediment bulking or en masse failure to blame?

USGS Publications Warehouse

McGuire, Luke; Rengers, Francis K.; Kean, Jason W.; Staley, Dennis M.

2017-01-01

Postwildfire debris flows are frequently triggered by runoff following high-intensity rainfall, but the physical mechanisms by which water-dominated flows transition to debris flows are poorly understood relative to debris flow initiation from shallow landslides. In this study, we combined a numerical model with high-resolution hydrologic and geomorphic data sets to test two different hypotheses for debris flow initiation during a rainfall event that produced numerous debris flows within a recently burned drainage basin. Based on simulations, large volumes of sediment eroded from the hillslopes were redeposited within the channel network throughout the storm, leading to the initiation of numerous debris flows as a result of the mass failure of sediment dams that built up within the channel. More generally, results provide a quantitative framework for assessing the potential of runoff-generated debris flows based on sediment supply and hydrologic conditions.

A highly accurate symmetric optical flow based high-dimensional nonlinear spatial normalization of brain images.

PubMed

Wen, Ying; Hou, Lili; He, Lianghua; Peterson, Bradley S; Xu, Dongrong

2015-05-01

Spatial normalization plays a key role in voxel-based analyses of brain images. We propose a highly accurate algorithm for high-dimensional spatial normalization of brain images based on the technique of symmetric optical flow. We first construct a three dimension optical model with the consistency assumption of intensity and consistency of the gradient of intensity under a constraint of discontinuity-preserving spatio-temporal smoothness. Then, an efficient inverse consistency optical flow is proposed with aims of higher registration accuracy, where the flow is naturally symmetric. By employing a hierarchical strategy ranging from coarse to fine scales of resolution and a method of Euler-Lagrange numerical analysis, our algorithm is capable of registering brain images data. Experiments using both simulated and real datasets demonstrated that the accuracy of our algorithm is not only better than that of those traditional optical flow algorithms, but also comparable to other registration methods used extensively in the medical imaging community. Moreover, our registration algorithm is fully automated, requiring a very limited number of parameters and no manual intervention. Copyright © 2015 Elsevier Inc. All rights reserved.

High order entropy conservative central schemes for wide ranges of compressible gas dynamics and MHD flows

NASA Astrophysics Data System (ADS)

Sjögreen, Björn; Yee, H. C.

2018-07-01

The Sjogreen and Yee [31] high order entropy conservative numerical method for compressible gas dynamics is extended to include discontinuities and also extended to equations of ideal magnetohydrodynamics (MHD). The basic idea is based on Tadmor's [40] original work for inviscid perfect gas flows. For the MHD four formulations of the MHD are considered: (a) the conservative MHD, (b) the Godunov [14] non-conservative form, (c) the Janhunen [19] - MHD with magnetic field source terms, and (d) a MHD with source terms by Brackbill and Barnes [5]. Three forms of the high order entropy numerical fluxes for the MHD in the finite difference framework are constructed. They are based on the extension of the low order form of Chandrashekar and Klingenberg [9], and two forms with modifications of the Winters and Gassner [49] numerical fluxes. For flows containing discontinuities and multiscale turbulence fluctuations the high order entropy conservative numerical fluxes as the new base scheme under the Yee and Sjogreen [31] and Kotov et al. [21,22] high order nonlinear filter approach is developed. The added nonlinear filter step on the high order centered entropy conservative spatial base scheme is only utilized at isolated computational regions, while maintaining high accuracy almost everywhere for long time integration of unsteady flows and DNS and LES of turbulence computations. Representative test cases for both smooth flows and problems containing discontinuities for the gas dynamics and the ideal MHD are included. The results illustrate the improved stability by using the high order entropy conservative numerical flux as the base scheme instead of the pure high order central scheme.

Gene delivery by microfluidic flow-through electroporation based on constant DC and AC field.

PubMed

Geng, Tao; Zhan, Yihong; Lu, Chang

2012-01-01

Electroporation is one of the most widely used physical methods to deliver exogenous nucleic acids into cells with high efficiency and low toxicity. Conventional electroporation systems typically require expensive pulse generators to provide short electrical pulses at high voltage. In this work, we demonstrate a flow-through electroporation method for continuous transfection of cells based on disposable chips, a syringe pump, and a low-cost power supply that provides a constant voltage. We successfully transfect cells using either DC or AC voltage with high flow rates (ranging from 40 µl/min to 20 ml/min) and high efficiency (up to 75%). We also enable the entire cell membrane to be uniformly permeabilized and dramatically improve gene delivery by inducing complex migrations of cells during the flow.

Development of an Active Flow Control Technique for an Airplane High-Lift Configuration

NASA Technical Reports Server (NTRS)

Shmilovich, Arvin; Yadlin, Yoram; Dickey, Eric D.; Hartwich, Peter M.; Khodadoust, Abdi

2017-01-01

This study focuses on Active Flow Control methods used in conjunction with airplane high-lift systems. The project is motivated by the simplified high-lift system, which offers enhanced airplane performance compared to conventional high-lift systems. Computational simulations are used to guide the implementation of preferred flow control methods, which require a fluidic supply. It is first demonstrated that flow control applied to a high-lift configuration that consists of simple hinge flaps is capable of attaining the performance of the conventional high-lift counterpart. A set of flow control techniques has been subsequently considered to identify promising candidates, where the central requirement is that the mass flow for actuation has to be within available resources onboard. The flow control methods are based on constant blowing, fluidic oscillators, and traverse actuation. The simulations indicate that the traverse actuation offers a substantial reduction in required mass flow, and it is especially effective when the frequency of actuation is consistent with the characteristic time scale of the flow.

Selected Streamflow Statistics and Regression Equations for Predicting Statistics at Stream Locations in Monroe County, Pennsylvania

USGS Publications Warehouse

Thompson, Ronald E.; Hoffman, Scott A.

2006-01-01

A suite of 28 streamflow statistics, ranging from extreme low to high flows, was computed for 17 continuous-record streamflow-gaging stations and predicted for 20 partial-record stations in Monroe County and contiguous counties in north-eastern Pennsylvania. The predicted statistics for the partial-record stations were based on regression analyses relating inter-mittent flow measurements made at the partial-record stations indexed to concurrent daily mean flows at continuous-record stations during base-flow conditions. The same statistics also were predicted for 134 ungaged stream locations in Monroe County on the basis of regression analyses relating the statistics to GIS-determined basin characteristics for the continuous-record station drainage areas. The prediction methodology for developing the regression equations used to estimate statistics was developed for estimating low-flow frequencies. This study and a companion study found that the methodology also has application potential for predicting intermediate- and high-flow statistics. The statistics included mean monthly flows, mean annual flow, 7-day low flows for three recurrence intervals, nine flow durations, mean annual base flow, and annual mean base flows for two recurrence intervals. Low standard errors of prediction and high coefficients of determination (R2) indicated good results in using the regression equations to predict the statistics. Regression equations for the larger flow statistics tended to have lower standard errors of prediction and higher coefficients of determination (R2) than equations for the smaller flow statistics. The report discusses the methodologies used in determining the statistics and the limitations of the statistics and the equations used to predict the statistics. Caution is indicated in using the predicted statistics for small drainage area situations. Study results constitute input needed by water-resource managers in Monroe County for planning purposes and evaluation of water-resources availability.

Fuzzy Temporal Logic Based Railway Passenger Flow Forecast Model

PubMed Central

Dou, Fei; Jia, Limin; Wang, Li; Xu, Jie; Huang, Yakun

2014-01-01

Passenger flow forecast is of essential importance to the organization of railway transportation and is one of the most important basics for the decision-making on transportation pattern and train operation planning. Passenger flow of high-speed railway features the quasi-periodic variations in a short time and complex nonlinear fluctuation because of existence of many influencing factors. In this study, a fuzzy temporal logic based passenger flow forecast model (FTLPFFM) is presented based on fuzzy logic relationship recognition techniques that predicts the short-term passenger flow for high-speed railway, and the forecast accuracy is also significantly improved. An applied case that uses the real-world data illustrates the precision and accuracy of FTLPFFM. For this applied case, the proposed model performs better than the k-nearest neighbor (KNN) and autoregressive integrated moving average (ARIMA) models. PMID:25431586

Flow Disturbance Characterization Measurements in the National Transonic Facility

NASA Technical Reports Server (NTRS)

King, Rudolph A.; Andino, Marlyn Y.; Melton, Latunia; Eppink, Jenna; Kegerise, Michael A.; Tsoi, Andrew

2012-01-01

Recent flow measurements have been acquired in the National Transonic Facility (NTF) to assess the unsteady flow environment in the test section. The primary purpose of the test is to determine the feasibility of the NTF to conduct laminar-flow-control testing and boundary-layer transition sensitive testing. The NTF can operate in two modes, warm (air) and cold/cryogenic (nitrogen) test conditions for testing full and semispan scaled models. The warm-air mode enables low to moderately high Reynolds numbers through the use of high tunnel pressure, and the nitrogen mode enables high Reynolds numbers up to flight conditions, depending on aircraft type and size, utilizing high tunnel pressure and cryogenic temperatures. NASA's Environmentally Responsible Aviation (ERA) project is interested in demonstrating different laminar-flow technologies at flight-relevant operating conditions throughout the transonic Mach number range and the NTF is well suited for the initial ground-based demonstrations. Roll polar data at selected test conditions were obtained to look at the uniformity of the flow disturbance field in the test section. Data acquired from the rake probes included mean total temperatures, mean and fluctuating static/total pressures, and mean and fluctuating hot-wire measurements. . Based on the current measurements and previous data, an assessment was made that the NTF is a suitable facility for ground-based demonstrations of laminar-flow technologies at flight-relevant conditions in the cryogenic mode.

An impact of environmental changes on flows in the reach scale under a range of climatic conditions

NASA Astrophysics Data System (ADS)

Karamuz, Emilia; Romanowicz, Renata J.

2016-04-01

The present paper combines detection and adequate identification of causes of changes in flow regime at cross-sections along the Middle River Vistula reach using different methods. Two main experimental set ups (designs) have been applied to study the changes, a moving three-year window and low- and high-flow event based approach. In the first experiment, a Stochastic Transfer Function (STF) model and a quantile-based statistical analysis of flow patterns were compared. These two methods are based on the analysis of changes of the STF model parameters and standardised differences of flow quantile values. In the second experiment, in addition to the STF-based also a 1-D distributed model, MIKE11 was applied. The first step of the procedure used in the study is to define the river reaches that have recorded information on land use and water management changes. The second task is to perform the moving window analysis of standardised differences of flow quantiles and moving window optimisation of the STF model for flow routing. The third step consists of an optimisation of the STF and MIKE11 models for high- and low-flow events. The final step is to analyse the results and relate the standardised quantile changes and model parameter changes to historical land use changes and water management practices. Results indicate that both models give consistent assessment of changes in the channel for medium and high flows. ACKNOWLEDGEMENTS This research was supported by the Institute of Geophysics Polish Academy of Sciences through the Young Scientist Grant no. 3b/IGF PAN/2015.

A High-Order Immersed Boundary Method for Acoustic Wave Scattering and Low-Mach Number Flow-Induced Sound in Complex Geometries

PubMed Central

Seo, Jung Hee; Mittal, Rajat

2010-01-01

A new sharp-interface immersed boundary method based approach for the computation of low-Mach number flow-induced sound around complex geometries is described. The underlying approach is based on a hydrodynamic/acoustic splitting technique where the incompressible flow is first computed using a second-order accurate immersed boundary solver. This is followed by the computation of sound using the linearized perturbed compressible equations (LPCE). The primary contribution of the current work is the development of a versatile, high-order accurate immersed boundary method for solving the LPCE in complex domains. This new method applies the boundary condition on the immersed boundary to a high-order by combining the ghost-cell approach with a weighted least-squares error method based on a high-order approximating polynomial. The method is validated for canonical acoustic wave scattering and flow-induced noise problems. Applications of this technique to relatively complex cases of practical interest are also presented. PMID:21318129

3-D High-Lift Flow-Physics Experiment - Transition Measurements

NASA Technical Reports Server (NTRS)

McGinley, Catherine B.; Jenkins, Luther N.; Watson, Ralph D.; Bertelrud, Arild

2005-01-01

An analysis of the flow state on a trapezoidal wing model from the NASA 3-D High Lift Flow Physics Experiment is presented. The objective of the experiment was to characterize the flow over a non-proprietary semi-span three-element high-lift configuration to aid in assessing the state of the art in the computation of three-dimensional high-lift flows. Surface pressures and hot-film sensors are used to determine the flow conditions on the slat, main, and flap. The locations of the attachments lines and the values of the attachment line Reynolds number are estimated based on the model surface pressures. Data from the hot-films are used to determine if the flow is laminar, transitional, or turbulent by examining the hot-film time histories, statistics, and frequency spectra.

Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cary, Robert E.

2015-12-08

Highly simplified lateral flow chromatographic nucleic acid sample preparation methods, devices, and integrated systems are provided for the efficient concentration of trace samples and the removal of nucleic acid amplification inhibitors. Methods for capturing and reducing inhibitors of nucleic acid amplification reactions, such as humic acid, using polyvinylpyrrolidone treated elements of the lateral flow device are also provided. Further provided are passive fluid control methods and systems for use in lateral flow assays.

Highly simplified lateral flow-based nucleic acid sample preparation and passive fluid flow control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cary, Robert B.

Highly simplified lateral flow chromatographic nucleic acid sample preparation methods, devices, and integrated systems are provided for the efficient concentration of trace samples and the removal of nucleic acid amplification inhibitors. Methods for capturing and reducing inhibitors of nucleic acid amplification reactions, such as humic acid, using polyvinylpyrrolidone treated elements of the lateral flow device are also provided. Further provided are passive fluid control methods and systems for use in lateral flow assays.

Multiplex immunoassay for persistent organic pollutants in tilapia: Comparison of imaging- and flow cytometry-based platforms using spectrally encoded paramagnetic microspheres

USDA-ARS?s Scientific Manuscript database

Recent developments in spectrally encoded microspheres (SEMs)-based technologies provide high multiplexing possibilities. Most SEMs-based assays required a flow cytometer with sophisticated fluidics and optics. The new imaging superparamagnetic SEMs-based platform transports SEMs with considerably ...

Large eddy simulations of time-dependent and buoyancy-driven channel flows

NASA Technical Reports Server (NTRS)

Cabot, William H.

1993-01-01

The primary goal of this work has been to assess the performance of the dynamic SGS model in the large eddy simulation (LES) of channel flows in a variety of situations, viz., in temporal development of channel flow turned by a transverse pressure gradient and especially in buoyancy-driven turbulent flows such as Rayleigh-Benard and internally heated channel convection. For buoyancy-driven flows, there are additional buoyant terms that are possible in the base models, and one objective has been to determine if the dynamic SGS model results are sensitive to such terms. The ultimate goal is to determine the minimal base model needed in the dynamic SGS model to provide accurate results in flows with more complicated physical features. In addition, a program of direct numerical simulation (DNS) of fully compressible channel convection has been undertaken to determine stratification and compressibility effects. These simulations are intended to provide a comparative base for performing the LES of compressible (or highly stratified, pseudo-compressible) convection at high Reynolds number in the future.

A biomimetic redox flow battery based on flavin mononucleotide

PubMed Central

Orita, Akihiro; Verde, Michael G.; Sakai, Masanori; Meng, Ying Shirley

2016-01-01

The versatility in design of redox flow batteries makes them apt to efficiently store energy in large-scale applications at low cost. The discovery of inexpensive organic electroactive materials for use in aqueous flow battery electrolytes is highly attractive, but is thus far limited. Here we report on a flow battery using an aqueous electrolyte based on the sodium salt of flavin mononucleotide. Flavins are highly versatile electroactive molecules, which catalyse a multitude of redox reactions in biological systems. We use nicotinamide (vitamin B3) as a hydrotropic agent to enhance the water solubility of flavin mononucleotide. A redox flow battery using flavin mononucleotide negative and ferrocyanide positive electrolytes in strong base shows stable cycling performance, with over 99% capacity retention over the course of 100 cycles. We hypothesize that this is enabled due to the oxidized and reduced forms of FMN-Na being stabilized by resonance structures. PMID:27767026

A biomimetic redox flow battery based on flavin mononucleotide

NASA Astrophysics Data System (ADS)

Orita, Akihiro; Verde, Michael G.; Sakai, Masanori; Meng, Ying Shirley

2016-10-01

The versatility in design of redox flow batteries makes them apt to efficiently store energy in large-scale applications at low cost. The discovery of inexpensive organic electroactive materials for use in aqueous flow battery electrolytes is highly attractive, but is thus far limited. Here we report on a flow battery using an aqueous electrolyte based on the sodium salt of flavin mononucleotide. Flavins are highly versatile electroactive molecules, which catalyse a multitude of redox reactions in biological systems. We use nicotinamide (vitamin B3) as a hydrotropic agent to enhance the water solubility of flavin mononucleotide. A redox flow battery using flavin mononucleotide negative and ferrocyanide positive electrolytes in strong base shows stable cycling performance, with over 99% capacity retention over the course of 100 cycles. We hypothesize that this is enabled due to the oxidized and reduced forms of FMN-Na being stabilized by resonance structures.

A biomimetic redox flow battery based on flavin mononucleotide.

PubMed

Orita, Akihiro; Verde, Michael G; Sakai, Masanori; Meng, Ying Shirley

2016-10-21

The versatility in design of redox flow batteries makes them apt to efficiently store energy in large-scale applications at low cost. The discovery of inexpensive organic electroactive materials for use in aqueous flow battery electrolytes is highly attractive, but is thus far limited. Here we report on a flow battery using an aqueous electrolyte based on the sodium salt of flavin mononucleotide. Flavins are highly versatile electroactive molecules, which catalyse a multitude of redox reactions in biological systems. We use nicotinamide (vitamin B3) as a hydrotropic agent to enhance the water solubility of flavin mononucleotide. A redox flow battery using flavin mononucleotide negative and ferrocyanide positive electrolytes in strong base shows stable cycling performance, with over 99% capacity retention over the course of 100 cycles. We hypothesize that this is enabled due to the oxidized and reduced forms of FMN-Na being stabilized by resonance structures.

Forecasting the short-term passenger flow on high-speed railway with neural networks.

PubMed

Xie, Mei-Quan; Li, Xia-Miao; Zhou, Wen-Liang; Fu, Yan-Bing

2014-01-01

Short-term passenger flow forecasting is an important component of transportation systems. The forecasting result can be applied to support transportation system operation and management such as operation planning and revenue management. In this paper, a divide-and-conquer method based on neural network and origin-destination (OD) matrix estimation is developed to forecast the short-term passenger flow in high-speed railway system. There are three steps in the forecasting method. Firstly, the numbers of passengers who arrive at each station or depart from each station are obtained from historical passenger flow data, which are OD matrices in this paper. Secondly, short-term passenger flow forecasting of the numbers of passengers who arrive at each station or depart from each station based on neural network is realized. At last, the OD matrices in short-term time are obtained with an OD matrix estimation method. The experimental results indicate that the proposed divide-and-conquer method performs well in forecasting the short-term passenger flow on high-speed railway.

Fluid mechanics based classification of the respiratory efficiency of several nasal cavities.

PubMed

Lintermann, Andreas; Meinke, Matthias; Schröder, Wolfgang

2013-11-01

The flow in the human nasal cavity is of great importance to understand rhinologic pathologies like impaired respiration or heating capabilities, a diminished sense of taste and smell, and the presence of dry mucous membranes. To numerically analyze this flow problem a highly efficient and scalable Thermal Lattice-BGK (TLBGK) solver is used, which is very well suited for flows in intricate geometries. The generation of the computational mesh is completely automatic and highly parallelized such that it can be executed efficiently on High Performance Computers (HPCs). An evaluation of the functionality of nasal cavities is based on an analysis of pressure drop, secondary flow structures, wall-shear stress distributions, and temperature variations from the nostrils to the pharynx. The results of the flow fields of three completely different nasal cavities allow their classification into ability groups and support the a priori decision process on surgical interventions. © 2013 Elsevier Ltd. All rights reserved.

Sensing and Active Flow Control for Advanced BWB Propulsion-Airframe Integration Concepts

NASA Technical Reports Server (NTRS)

Fleming, John; Anderson, Jason; Ng, Wing; Harrison, Neal

2005-01-01

In order to realize the substantial performance benefits of serpentine boundary layer ingesting diffusers, this study investigated the use of enabling flow control methods to reduce engine-face flow distortion. Computational methods and novel flow control modeling techniques were utilized that allowed for rapid, accurate analysis of flow control geometries. Results were validated experimentally using the Techsburg Ejector-based wind tunnel facility; this facility is capable of simulating the high-altitude, high subsonic Mach number conditions representative of BWB cruise conditions.

A biogeochemical comparison of two well-buffered catchments with contrasting histories of acid deposition

USGS Publications Warehouse

Shanley, J.B.; Kram, P.; Hruska, J.; Bullen, T.D.

2004-01-01

Much of the biogeochemical cycling research in catchments in the past 25 years has been driven by acid deposition research funding. This research has focused on vulnerable base-poor systems; catchments on alkaline lithologies have received little attention. In regions of high acid loadings, however, even well-buffered catchments are susceptible to forest decline and episodes of low alkalinity in streamwater. As part of a collaboration between the Czech and U.S. Geological Surveys, we compared biogeochemical patterns in two well-studied, well-buffered catchments: Pluhuv Bor in the western Czech Republic, which has received high loading of atmospheric acidity, and Sleepers River Research Watershed in Vermont, U.S.A., where acid loading has been considerably less. Despite differences in lithology, wetness, forest type, and glacial history, the catchments displayed similar patterns of solute concentrations and flow. At both catchments, base cation and alkalinity diluted with increasing flow, whereas nitrate and dissolved organic carbon increased with increasing flow. Sulfate diluted with increasing flow at Sleepers River, while at Pluhuv Bor the sulfate-flow relation shifted from positive to negative as atmospheric sulfur (S) loadings decreased and soil S pools were depleted during the 1990s. At high flow, alkalinity decreased to near 100 ??eq L-1 at Pluhuv Bor compared to 400 ??eq L-1 at Sleepers River. Despite the large amounts of S flushed from Pluhuv Bor soils, these alkalinity declines were caused solely by dilution, which was greater at Pluhuv Bor relative to Sleepers River due to greater contributions from shallow flow paths at high flow. Although the historical high S loading at Pluhuv Bor has caused soil acidification and possible forest damage, it has had little effect on the acid/base status of streamwater in this well-buffered catchment. ?? 2004 Kluwer Academic Publishers.

Effects of deposition temperature and ammonia flow on metal-organic chemical vapor deposition of hexagonal boron nitride

NASA Astrophysics Data System (ADS)

Rice, Anthony; Allerman, Andrew; Crawford, Mary; Beechem, Thomas; Ohta, Taisuke; Spataru, Catalin; Figiel, Jeffrey; Smith, Michael

2018-03-01

The use of metal-organic chemical vapor deposition at high temperature is investigated as a means to produce epitaxial hexagonal boron nitride (hBN) at the wafer scale. Several categories of hBN films were found to exist based upon precursor flows and deposition temperature. Low, intermediate, and high NH3 flow regimes were found to lead to fundamentally different deposition behaviors. The low NH3 flow regimes yielded discolored films of boron sub-nitride. The intermediate NH3 flow regime yielded stoichiometric films that could be deposited as thick films. The high NH3 flow regime yielded self-limited deposition with thicknesses limited to a few mono-layers. A Langmuir-Hinshelwood mechanism is proposed to explain the onset of self-limited behavior for the high NH3 flow regime. Photoluminescence characterization determined that the intermediate and high NH3 flow regimes could be further divided into low and high temperature behaviors with a boundary at 1500 °C. Films deposited with both high NH3 flow and high temperature exhibited room temperature free exciton emission at 210 nm and 215.9 nm.

A High Performance Pulsatile Pump for Aortic Flow Experiments in 3-Dimensional Models.

PubMed

Chaudhury, Rafeed A; Atlasman, Victor; Pathangey, Girish; Pracht, Nicholas; Adrian, Ronald J; Frakes, David H

2016-06-01

Aortic pathologies such as coarctation, dissection, and aneurysm represent a particularly emergent class of cardiovascular diseases. Computational simulations of aortic flows are growing increasingly important as tools for gaining understanding of these pathologies, as well as for planning their surgical repair. In vitro experiments are required to validate the simulations against real world data, and the experiments require a pulsatile flow pump system that can provide physiologic flow conditions characteristic of the aorta. We designed a newly capable piston-based pulsatile flow pump system that can generate high volume flow rates (850 mL/s), replicate physiologic waveforms, and pump high viscosity fluids against large impedances. The system is also compatible with a broad range of fluid types, and is operable in magnetic resonance imaging environments. Performance of the system was validated using image processing-based analysis of piston motion as well as particle image velocimetry. The new system represents a more capable pumping solution for aortic flow experiments than other available designs, and can be manufactured at a relatively low cost.

The temperature measurement research for high-speed flow based on tunable diode laser absorption spectroscopy

NASA Astrophysics Data System (ADS)

Di, Yue; Jin, Yi; Jiang, Hong-liang; Zhai, Chao

2013-09-01

Due to the particularity of the high-speed flow, in order to accurately obtain its' temperature, the measurement system should has some characteristics of not interfereing with the flow, non-contact measurement and high time resolution. The traditional measurement method cannot meet the above requirements, however the measurement method based on tunable diode laser absorption spectroscopy (TDLAS) technology can meet the requirements for high-speed flow temperature measurement. When the near-infared light of a specific frequency is through the media to be measured, it will be absorbed by the water vapor molecules and then the transmission light intensity is detected by the detector. The temperature of the water vapor which is also the high-speed flow temperature, can be accurately obtained by the Beer-Lambert law. This paper focused on the research of absorption spectrum method for high speed flow temperature measurement with the scope of 250K-500K. Firstly, spectral line selection method for low temperature measurement of high-speed flow is discussed. Selected absorption lines should be isolated and have a high peak absorption within the range of 250-500K, at the same time the interference of the other lines should be avoided, so that a high measurement accuracy can be obtained. According to the near-infrared absorption spectra characteristics of water vapor, four absorption lines at the near 1395 nm and 1409 nm are selected. Secondly, a system for the temperature measurement of the water vapor in the high-speed flow is established. Room temperature are measured through two methods, direct absorption spectroscopy (DAS) and wavelength modulation spectroscopy (WMS) ,the results show that this system can realize on-line measurement of the temperature and the measurement error is about 3%. Finally, the system will be used for temperature measurement of the high-speed flow in the shock tunnel, its feasibility of measurement is analyzed.

Large eddy simulations and direct numerical simulations of high speed turbulent reacting flows

NASA Technical Reports Server (NTRS)

Givi, Peyman; Madnia, Cyrus K.; Steinberger, Craig J.

1990-01-01

This research is involved with the implementation of advanced computational schemes based on large eddy simulations (LES) and direct numerical simulations (DNS) to study the phenomenon of mixing and its coupling with chemical reactions in compressible turbulent flows. In the efforts related to LES, a research program to extend the present capabilities of this method was initiated for the treatment of chemically reacting flows. In the DNS efforts, the focus is on detailed investigations of the effects of compressibility, heat release, and non-equilibrium kinetics modelings in high speed reacting flows. Emphasis was on the simulations of simple flows, namely homogeneous compressible flows, and temporally developing high speed mixing layers.

Total synthesis of feglymycin based on a linear/convergent hybrid approach using micro-flow amide bond formation

NASA Astrophysics Data System (ADS)

Fuse, Shinichiro; Mifune, Yuto; Nakamura, Hiroyuki; Tanaka, Hiroshi

2016-11-01

Feglymycin is a naturally occurring, anti-HIV and antimicrobial 13-mer peptide that includes highly racemizable 3,5-dihydroxyphenylglycines (Dpgs). Here we describe the total synthesis of feglymycin based on a linear/convergent hybrid approach. Our originally developed micro-flow amide bond formation enabled highly racemizable peptide chain elongation based on a linear approach that was previously considered impossible. Our developed approach will enable the practical preparation of biologically active oligopeptides that contain highly racemizable amino acids, which are attractive drug candidates.

Influence of observers and stream flow on northern two-lined salamander (Eurycea bislineata bislineata) relative abundance estimates in Acadia and Shenandoah National Parks, USA

USGS Publications Warehouse

Crocker, J.B.; Bank, M.S.; Loftin, C.S.; Jung Brown, R.E.

2007-01-01

We investigated effects of observers and stream flow on Northern Two-Lined Salamander (Eurycea bislineata bislineata) counts in streams in Acadia (ANP) and Shenandoah National Parks (SNP). We counted salamanders in 22 ANP streams during high flow (May to June 2002) and during low flow (July 2002). We also counted salamanders in SNP in nine streams during high flow (summer 2003) and 11 streams during low flow (summers 2001?02, 2004). In 2002, we used a modified cover-controlled active search method with a first and second observer. In succession, observers turned over 100 rocks along five 1-m belt transects across the streambed. The difference between observers in total salamander counts was not significant. We counted fewer E. b. bislineata during high flow conditions, confirming that detection of this species is reduced during high flow periods and that assessment of stream salamander relative abundance is likely more reliable during low or base flow conditions.

Research on virtual network load balancing based on OpenFlow

NASA Astrophysics Data System (ADS)

Peng, Rong; Ding, Lei

2017-08-01

The Network based on OpenFlow technology separate the control module and data forwarding module. Global deployment of load balancing strategy through network view of control plane is fast and of high efficiency. This paper proposes a Weighted Round-Robin Scheduling algorithm for virtual network and a load balancing plan for server load based on OpenFlow. Load of service nodes and load balancing tasks distribution algorithm will be taken into account.

Numerical Investigation of Physical Processes in High-Temperature MEMS-based Nozzle Flows

NASA Astrophysics Data System (ADS)

Alexeenko, A. A.; Levin, D. A.; Gimelshein, S. F.; Reed, B. D.

2003-05-01

Three-dimensional high-temperature flows in a MEMS-based micronozzle has been modeled using the DSMC method for Reynolds number at the throat from 30 to 440 and two different propellants. For these conditions, the gas flow and thrust performance are strongly influenced by surface effects, including friction and heat transfer losses. The calculated specific impulse is about 170 sec for Re=440 and about 120 sec for Re=43. In addition, the gas-surface interaction is the main mechanism for the change in vibrational energy of molecules in such flows. The calculated infrared spectra for the LAX112 propellant suggest that the infrared signal from such plumes can be detected and used to determine the influence of the cold wall boundary layer on the flow parameters at the nozzle exit.

Vulnerability of streams to legacy nitrate sources

USGS Publications Warehouse

Tesoriero, Anthony J.; Duff, John H.; Saad, David A.; Spahr, Norman E.; Wolock, David M.

2013-01-01

The influence of hydrogeologic setting on the susceptibility of streams to legacy nitrate was examined at seven study sites having a wide range of base flow index (BFI) values. BFI is the ratio of base flow to total streamflow volume. The portion of annual stream nitrate loads from base flow was strongly correlated with BFI. Furthermore, dissolved oxygen concentrations in streambed pore water were significantly higher in high BFI watersheds than in low BFI watersheds suggesting that geochemical conditions favor nitrate transport through the bed when BFI is high. Results from a groundwater-surface water interaction study at a high BFI watershed indicate that decades old nitrate-laden water is discharging to this stream. These findings indicate that high nitrate levels in this stream may be sustained for decades to come regardless of current practices. It is hypothesized that a first approximation of stream vulnerability to legacy nutrients may be made by geospatial analysis of watersheds with high nitrogen inputs and a strong connection to groundwater (e.g., high BFI).

Survey of literature on convective heat transfer coefficients and recovery factors for high atmosphere thermometry

NASA Technical Reports Server (NTRS)

Chung, S.

1973-01-01

Heat transfer phenomena of rarefied gas flows is discussed based on a literature survey of analytical and experimental rarefied gas dynamics. Subsonic flows are emphasized for the purposes of meteorological thermometry in the high atmosphere. The heat transfer coefficients for three basic geometries are given in the regimes of free molecular flow, transition flow, slip flow, and continuum flow. Different types of heat phenomena, and the analysis of theoretical and experimental data are presented. The uncertainties calculated from the interpolation rule compared with the available experimental data are discussed. The recovery factor for each geometry in subsonic rarefied flows is also given.

Method and apparatus for making articles from particle based materials

DOEpatents

Moorhead, Arthur J.; Menchhofer, Paul A.

1995-01-01

A method and apparatus for the production of articles made of a particle-based material; e.g., ceramics and sintered metals. In accordance with the invention, a thermally settable slurry containing a relatively high concentration of the particles is conveyed through an elongate flow area having a desired cross-sectional configuration. The slurry is heated as it is advanced through the flow area causing the slurry to set or harden in a shape which conforms to the cross-sectional configuration of the flow area. The material discharges from the flow area as a self-supporting solid of near net final dimensions. The article may then be sintered to consolidate the particles and provide a high density product.

Numerical simulation of polishing U-tube based on solid-liquid two-phase

NASA Astrophysics Data System (ADS)

Li, Jun-ye; Meng, Wen-qing; Wu, Gui-ling; Hu, Jing-lei; Wang, Bao-zuo

2018-03-01

As the advanced technology to solve the ultra-precision machining of small hole structure parts and complex cavity parts, the abrasive grain flow processing technology has the characteristics of high efficiency, high quality and low cost. So this technology in many areas of precision machining has an important role. Based on the theory of solid-liquid two-phase flow coupling, a solid-liquid two-phase MIXTURE model is used to simulate the abrasive flow polishing process on the inner surface of U-tube, and the temperature, turbulent viscosity and turbulent dissipation rate in the process of abrasive flow machining of U-tube were compared and analyzed under different inlet pressure. In this paper, the influence of different inlet pressure on the surface quality of the workpiece during abrasive flow machining is studied and discussed, which provides a theoretical basis for the research of abrasive flow machining process.

Real-time Image Processing for Microscopy-based Label-free Imaging Flow Cytometry in a Microfluidic Chip.

PubMed

Heo, Young Jin; Lee, Donghyeon; Kang, Junsu; Lee, Keondo; Chung, Wan Kyun

2017-09-14

Imaging flow cytometry (IFC) is an emerging technology that acquires single-cell images at high-throughput for analysis of a cell population. Rich information that comes from high sensitivity and spatial resolution of a single-cell microscopic image is beneficial for single-cell analysis in various biological applications. In this paper, we present a fast image-processing pipeline (R-MOD: Real-time Moving Object Detector) based on deep learning for high-throughput microscopy-based label-free IFC in a microfluidic chip. The R-MOD pipeline acquires all single-cell images of cells in flow, and identifies the acquired images as a real-time process with minimum hardware that consists of a microscope and a high-speed camera. Experiments show that R-MOD has the fast and reliable accuracy (500 fps and 93.3% mAP), and is expected to be used as a powerful tool for biomedical and clinical applications.

High frequency flow-structural interaction in dense subsonic fluids

NASA Technical Reports Server (NTRS)

Liu, Baw-Lin; Ofarrell, J. M.

1995-01-01

Prediction of the detailed dynamic behavior in rocket propellant feed systems and engines and other such high-energy fluid systems requires precise analysis to assure structural performance. Designs sometimes require placement of bluff bodies in a flow passage. Additionally, there are flexibilities in ducts, liners, and piping systems. A design handbook and interactive data base have been developed for assessing flow/structural interactions to be used as a tool in design and development, to evaluate applicable geometries before problems develop, or to eliminate or minimize problems with existing hardware. This is a compilation of analytical/empirical data and techniques to evaluate detailed dynamic characteristics of both the fluid and structures. These techniques have direct applicability to rocket engine internal flow passages, hot gas drive systems, and vehicle propellant feed systems. Organization of the handbook is by basic geometries for estimating Strouhal numbers, added mass effects, mode shapes for various end constraints, critical onset flow conditions, and possible structural response amplitudes. Emphasis is on dense fluids and high structural loading potential for fatigue at low subsonic flow speeds where high-frequency excitations are possible. Avoidance and corrective measure illustrations are presented together with analytical curve fits for predictions compiled from a comprehensive data base.

Robust-mode analysis of hydrodynamic flows

NASA Astrophysics Data System (ADS)

Roy, Sukesh; Gord, James R.; Hua, Jia-Chen; Gunaratne, Gemunu H.

2017-04-01

The emergence of techniques to extract high-frequency high-resolution data introduces a new avenue for modal decomposition to assess the underlying dynamics, especially of complex flows. However, this task requires the differentiation of robust, repeatable flow constituents from noise and other irregular features of a flow. Traditional approaches involving low-pass filtering and principle components analysis have shortcomings. The approach outlined here, referred to as robust-mode analysis, is based on Koopman decomposition. Three applications to (a) a counter-rotating cellular flame state, (b) variations in financial markets, and (c) turbulent injector flows are provided.

Fundamentals of microfluidics for high school students with no prior knowledge of fluid mechanics.

PubMed

Tandon, Vishal; Peck, Walter

2013-01-01

Three microfluidics-based laboratory exercises were developed and implemented in a high school science classroom setting. The first exercise demonstrated ways in which flows are characterized, including viscosity, turbulence, shear stress, reversibility, compressibility, and hydrodynamic resistance. Students characterized flows in poly(dimethylsiloxane) microfluidic devices in the other two exercises, where they observed the mixing characteristics of laminar flows, and conservation of volumetric flow rate for incompressible flows. In surveys, the students self-reported increased knowledge of microfluidics, and an improved attitude toward science and nanotechnology.

Concentrations and Loads of Nutrients and Suspended Sediments in Englesby Brook and Little Otter Creek, Lake Champlain Basin, Vermont, 2000-2005

USGS Publications Warehouse

Medalie, Laura

2007-01-01

The effectiveness of best-management practices (BMPs) in improving water quality in Lake Champlain tributaries was evaluated from 2000 through 2005 on the basis of analysis of data collected on concentrations of total phosphorus and suspended sediment in Englesby Brook, an urban stream in Burlington, and Little Otter Creek, an agricultural stream in Ferrisburg. Data also were collected on concentrations of total nitrogen in the Englesby Brook watershed. In the winter of 2001-2002, one of three planned structural BMPs was installed in the urban watershed. At approximately the same time, a set of barnyard BMPs was installed in the agricultural watershed; however, the other planned BMPs, which included streambank fencing and nutrient management, were not implemented within the study period. At Englesby Brook, concentrations of phosphorus ranged from 0.024 to 0.3 milligrams per liter (mg/L) during base-flow and from 0.032 to 11.8 mg/L during high-flow conditions. Concentrations of suspended sediment ranged from 3 to 189 mg/L during base-flow and from 5 to 6,880 mg/L during high-flow conditions. An assessment of the effectiveness of an urban BMP was made by comparing concentrations and loads of phosphorus and suspended sediment before and after a golf-course irrigation pond in the Englesby Brook watershed was retrofitted with the objective of reducing sediment transport. Results from a modified paired watershed study design showed that the BMP reduced concentrations of phosphorus and suspended sediment during high-flow events - when average streamflow was greater than 3 cubic feet per second. While construction of the BMP did not reduce storm loads of phosphorus or suspended sediment, an evaluation of changes in slope of double-mass curves showing cumulative monthly streamflow plotted against cumulative monthly loads indicated a possible reduction in cumulative loads of phosphorus and suspended sediment after BMP construction. Results from the Little Otter Creek assessment of agricultural BMPs showed that concentrations of phosphorus ranged from 0.016 to 0.141 mg/L during base-flow and from 0.019 to 0.565 mg/L during high-flow conditions at the upstream monitoring station. Concentrations of suspended sediment ranged from 2 to 13 mg/L during base-flow and from 1 to 473 mg/L during high-flow conditions at the upstream monitoring station. Concentrations of phosphorus ranged from 0.018 to 0.233 mg/L during base-flow and from 0.019 to 1.95 mg/L during high-flow conditions at the downstream monitoring station. Concentrations of suspended sediment ranged from 10 to 132 mg/L during base-flow and from 8 to 1,190 mg/L during high-flow conditions at the downstream monitoring station. Annual loads of phosphorus at the downstream monitoring station were significantly larger than loads at the upstream monitoring station, and annual loads of suspended sediment at the downstream monitoring station were larger than loads at the upstream monitoring station for 4 out of 6 years. On a monthly basis, loads of phosphorus and suspended sediment at the downstream monitoring station were significantly larger than loads at the upstream monitoring station. Pairs of concentrations of phosphorus and monthly loads of phosphorus and suspended sediment from the upstream and downstream monitoring stations were evaluated using the paired watershed study design. The only significant reduction between the calibration and treatment periods was for monthly loads of phosphorus; all other evaluations showed no change between periods.

Four-Nozzle Benchmark Wind Tunnel Model USA Code Solutions for Simulation of Multiple Rocket Base Flow Recirculation at 145,000 Feet Altitude

NASA Technical Reports Server (NTRS)

Dougherty, N. S.; Johnson, S. L.

1993-01-01

Multiple rocket exhaust plume interactions at high altitudes can produce base flow recirculation with attendant alteration of the base pressure coefficient and increased base heating. A search for a good wind tunnel benchmark problem to check grid clustering technique and turbulence modeling turned up the experiment done at AEDC in 1961 by Goethert and Matz on a 4.25-in. diameter domed missile base model with four rocket nozzles. This wind tunnel model with varied external bleed air flow for the base flow wake produced measured p/p(sub ref) at the center of the base as high as 3.3 due to plume flow recirculation back onto the base. At that time in 1961, relatively inexpensive experimentation with air at gamma = 1.4 and nozzle A(sub e)/A of 10.6 and theta(sub n) = 7.55 deg with P(sub c) = 155 psia simulated a LO2/LH2 rocket exhaust plume with gamma = 1.20, A(sub e)/A of 78 and P(sub c) about 1,000 psia. An array of base pressure taps on the aft dome gave a clear measurement of the plume recirculation effects at p(infinity) = 4.76 psfa corresponding to 145,000 ft altitude. Our CFD computations of the flow field with direct comparison of computed-versus-measured base pressure distribution (across the dome) provide detailed information on velocities and particle traces as well eddy viscosity in the base and nozzle region. The solution was obtained using a six-zone mesh with 284,000 grid points for one quadrant taking advantage of symmetry. Results are compared using a zero-equation algebraic and a one-equation pointwise R(sub t) turbulence model (work in progress). Good agreement with the experimental pressure data was obtained with both; and this benchmark showed the importance of: (1) proper grid clustering and (2) proper choice of turbulence modeling for rocket plume problems/recirculation at high altitude.

Mitigating the Hook Effect in Lateral Flow Sandwich Immunoassays Using Real-Time Reaction Kinetics.

PubMed

Rey, Elizabeth G; O'Dell, Dakota; Mehta, Saurabh; Erickson, David

2017-05-02

The quantification of analyte concentrations using lateral flow assays is a low-cost and user-friendly alternative to traditional lab-based assays. However, sandwich-type immunoassays are often limited by the high-dose hook effect, which causes falsely low results when analytes are present at very high concentrations. In this paper, we present a reaction kinetics-based technique that solves this problem, significantly increasing the dynamic range of these devices. With the use of a traditional sandwich lateral flow immunoassay, a portable imaging device, and a mobile interface, we demonstrate the technique by quantifying C-reactive protein concentrations in human serum over a large portion of the physiological range. The technique could be applied to any hook effect-limited sandwich lateral flow assay and has a high level of accuracy even in the hook effect range.

High resolution light-sheet based high-throughput imaging cytometry system enables visualization of intra-cellular organelles

NASA Astrophysics Data System (ADS)

Regmi, Raju; Mohan, Kavya; Mondal, Partha Pratim

2014-09-01

Visualization of intracellular organelles is achieved using a newly developed high throughput imaging cytometry system. This system interrogates the microfluidic channel using a sheet of light rather than the existing point-based scanning techniques. The advantages of the developed system are many, including, single-shot scanning of specimens flowing through the microfluidic channel at flow rate ranging from micro- to nano- lit./min. Moreover, this opens-up in-vivo imaging of sub-cellular structures and simultaneous cell counting in an imaging cytometry system. We recorded a maximum count of 2400 cells/min at a flow-rate of 700 nl/min, and simultaneous visualization of fluorescently-labeled mitochondrial network in HeLa cells during flow. The developed imaging cytometry system may find immediate application in biotechnology, fluorescence microscopy and nano-medicine.

Flow Control Research at NASA Langley in Support of High-Lift Augmentation

NASA Technical Reports Server (NTRS)

Sellers, William L., III; Jones, Gregory S.; Moore, Mark D.

2002-01-01

The paper describes the efforts at NASA Langley to apply active and passive flow control techniques for improved high-lift systems, and advanced vehicle concepts utilizing powered high-lift techniques. The development of simplified high-lift systems utilizing active flow control is shown to provide significant weight and drag reduction benefits based on system studies. Active flow control that focuses on separation, and the development of advanced circulation control wings (CCW) utilizing unsteady excitation techniques will be discussed. The advanced CCW airfoils can provide multifunctional controls throughout the flight envelope. Computational and experimental data are shown to illustrate the benefits and issues with implementation of the technology.

Enhanced model-based design of a high-throughput three dimensional micromixer driven by alternating-current electrothermal flow.

PubMed

Wu, Yupan; Ren, Yukun; Jiang, Hongyuan

2017-01-01

We propose a 3D microfluidic mixer based on the alternating current electrothermal (ACET) flow. The ACET vortex is produced by 3D electrodes embedded in the sidewall of the microchannel and is used to stir the fluidic sample throughout the entire channel depth. An optimized geometrical structure of the proposed 3D micromixer device is obtained based on the enhanced theoretical model of ACET flow and natural convection. We quantitatively analyze the flow field driven by the ACET, and a pattern of electrothermal microvortex is visualized by the micro-particle imaging velocimetry. Then, the mixing experiment is conducted using dye solutions with varying solution conductivities. Mixing efficiency can exceed 90% for electrolytes with 0.2 S/m (1 S/m) when the flow rate is 0.364 μL/min (0.728 μL/min) and the imposed peak-to-peak voltage is 52.5 V (35 V). A critical analysis of our micromixer in comparison with different mixer designs using a comparative mixing index is also performed. The ACET micromixer embedded with sidewall 3D electrodes can achieve a highly effective mixing performance and can generate high throughput in the continuous-flow condition. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

High Fidelity Simulations for Unsteady Flow Through the Orbiter LH2 Feedline Flowliner

NASA Technical Reports Server (NTRS)

Kiris, Cetin C.; Kwak, Dochan; Chan, William; Housman, Jeffrey

2005-01-01

High fidelity computations were carried out to analyze the orbiter M2 feedline flowliner. Various computational models were used to characterize the unsteady flow features in the turbopump, including the orbiter Low-Pressure-Fuel-Turbopump (LPFTP) inducer, the orbiter manifold and a test article used to represent the manifold. Unsteady flow originating from the orbiter LPFTP inducer is one of the major contributors to the high frequency cyclic loading that results in high cycle fatigue damage to the gimbal flowliners just upstream of the LPFTP. The flow fields for the orbiter manifold and representative test article are computed and analyzed for similarities and differences. An incompressible Navier-Stokes flow solver INS3D, based on the artificial compressibility method, was used to compute the flow of liquid hydrogen in each test article.

Navier-Stokes simulations of slender axisymmetric shapes in supersonic, turbulent flow

NASA Astrophysics Data System (ADS)

Moran, Kenneth J.; Beran, Philip S.

1994-07-01

Computational fluid dynamics is used to study flows about slender, axisymmetric bodies at very high speeds. Numerical experiments are conducted to simulate a broad range of flight conditions. Mach number is varied from 1.5 to 8 and Reynolds number is varied from 1 X 10(exp 6)/m to 10(exp 8)/m. The primary objective is to develop and validate a computational and methodology for the accurate simulation of a wide variety of flow structures. Accurate results are obtained for detached bow shocks, recompression shocks, corner-point expansions, base-flow recirculations, and turbulent boundary layers. Accuracy is assessed through comparison with theory and experimental data; computed surface pressure, shock structure, base-flow structure, and velocity profiles are within measurement accuracy throughout the range of conditions tested. The methodology is both practical and general: general in its applicability, and practicaal in its performance. To achieve high accuracy, modifications to previously reported techniques are implemented in the scheme. These modifications improve computed results in the vicinity of symmetry lines and in the base flow region, including the turbulent wake.

Forecasting the Short-Term Passenger Flow on High-Speed Railway with Neural Networks

PubMed Central

Xie, Mei-Quan; Li, Xia-Miao; Zhou, Wen-Liang; Fu, Yan-Bing

2014-01-01

Short-term passenger flow forecasting is an important component of transportation systems. The forecasting result can be applied to support transportation system operation and management such as operation planning and revenue management. In this paper, a divide-and-conquer method based on neural network and origin-destination (OD) matrix estimation is developed to forecast the short-term passenger flow in high-speed railway system. There are three steps in the forecasting method. Firstly, the numbers of passengers who arrive at each station or depart from each station are obtained from historical passenger flow data, which are OD matrices in this paper. Secondly, short-term passenger flow forecasting of the numbers of passengers who arrive at each station or depart from each station based on neural network is realized. At last, the OD matrices in short-term time are obtained with an OD matrix estimation method. The experimental results indicate that the proposed divide-and-conquer method performs well in forecasting the short-term passenger flow on high-speed railway. PMID:25544838

Cavitation erosion prediction based on analysis of flow dynamics and impact load spectra

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mihatsch, Michael S., E-mail: michael.mihatsch@aer.mw.tum.de; Schmidt, Steffen J.; Adams, Nikolaus A.

2015-10-15

Cavitation erosion is the consequence of repeated collapse-induced high pressure-loads on a material surface. The present paper assesses the prediction of impact load spectra of cavitating flows, i.e., the rate and intensity distribution of collapse events based on a detailed analysis of flow dynamics. Data are obtained from a numerical simulation which employs a density-based finite volume method, taking into account the compressibility of both phases, and resolves collapse-induced pressure waves. To determine the spectrum of collapse events in the fluid domain, we detect and quantify the collapse of isolated vapor structures. As reference configuration we consider the expansion ofmore » a liquid into a radially divergent gap which exhibits unsteady sheet and cloud cavitation. Analysis of simulation data shows that global cavitation dynamics and dominant flow events are well resolved, even though the spatial resolution is too coarse to resolve individual vapor bubbles. The inviscid flow model recovers increasingly fine-scale vapor structures and collapses with increasing resolution. We demonstrate that frequency and intensity of these collapse events scale with grid resolution. Scaling laws based on two reference lengths are introduced for this purpose. We show that upon applying these laws impact load spectra recorded on experimental and numerical pressure sensors agree with each other. Furthermore, correlation between experimental pitting rates and collapse-event rates is found. Locations of high maximum wall pressures and high densities of collapse events near walls obtained numerically agree well with areas of erosion damage in the experiment. The investigation shows that impact load spectra of cavitating flows can be inferred from flow data that captures the main vapor structures and wave dynamics without the need for resolving all flow scales.« less

Network community-based model reduction for vortical flows

NASA Astrophysics Data System (ADS)

Gopalakrishnan Meena, Muralikrishnan; Nair, Aditya G.; Taira, Kunihiko

2018-06-01

A network community-based reduced-order model is developed to capture key interactions among coherent structures in high-dimensional unsteady vortical flows. The present approach is data-inspired and founded on network-theoretic techniques to identify important vortical communities that are comprised of vortical elements that share similar dynamical behavior. The overall interaction-based physics of the high-dimensional flow field is distilled into the vortical community centroids, considerably reducing the system dimension. Taking advantage of these vortical interactions, the proposed methodology is applied to formulate reduced-order models for the inter-community dynamics of vortical flows, and predict lift and drag forces on bodies in wake flows. We demonstrate the capabilities of these models by accurately capturing the macroscopic dynamics of a collection of discrete point vortices, and the complex unsteady aerodynamic forces on a circular cylinder and an airfoil with a Gurney flap. The present formulation is found to be robust against simulated experimental noise and turbulence due to its integrating nature of the system reduction.

Direct Numerical Simulation of Incompressible Pipe Flow Using a B-Spline Spectral Method

NASA Technical Reports Server (NTRS)

Loulou, Patrick; Moser, Robert D.; Mansour, Nagi N.; Cantwell, Brian J.

1997-01-01

A numerical method based on b-spline polynomials was developed to study incompressible flows in cylindrical geometries. A b-spline method has the advantages of possessing spectral accuracy and the flexibility of standard finite element methods. Using this method it was possible to ensure regularity of the solution near the origin, i.e. smoothness and boundedness. Because b-splines have compact support, it is also possible to remove b-splines near the center to alleviate the constraint placed on the time step by an overly fine grid. Using the natural periodicity in the azimuthal direction and approximating the streamwise direction as periodic, so-called time evolving flow, greatly reduced the cost and complexity of the computations. A direct numerical simulation of pipe flow was carried out using the method described above at a Reynolds number of 5600 based on diameter and bulk velocity. General knowledge of pipe flow and the availability of experimental measurements make pipe flow the ideal test case with which to validate the numerical method. Results indicated that high flatness levels of the radial component of velocity in the near wall region are physical; regions of high radial velocity were detected and appear to be related to high speed streaks in the boundary layer. Budgets of Reynolds stress transport equations showed close similarity with those of channel flow. However contrary to channel flow, the log layer of pipe flow is not homogeneous for the present Reynolds number. A topological method based on a classification of the invariants of the velocity gradient tensor was used. Plotting iso-surfaces of the discriminant of the invariants proved to be a good method for identifying vortical eddies in the flow field.

A high-resolution Godunov method for compressible multi-material flow on overlapping grids

NASA Astrophysics Data System (ADS)

Banks, J. W.; Schwendeman, D. W.; Kapila, A. K.; Henshaw, W. D.

2007-04-01

A numerical method is described for inviscid, compressible, multi-material flow in two space dimensions. The flow is governed by the multi-material Euler equations with a general mixture equation of state. Composite overlapping grids are used to handle complex flow geometry and block-structured adaptive mesh refinement (AMR) is used to locally increase grid resolution near shocks and material interfaces. The discretization of the governing equations is based on a high-resolution Godunov method, but includes an energy correction designed to suppress numerical errors that develop near a material interface for standard, conservative shock-capturing schemes. The energy correction is constructed based on a uniform-pressure-velocity flow and is significant only near the captured interface. A variety of two-material flows are presented to verify the accuracy of the numerical approach and to illustrate its use. These flows assume an equation of state for the mixture based on the Jones-Wilkins-Lee (JWL) forms for the components. This equation of state includes a mixture of ideal gases as a special case. Flow problems considered include unsteady one-dimensional shock-interface collision, steady interaction of a planar interface and an oblique shock, planar shock interaction with a collection of gas-filled cylindrical inhomogeneities, and the impulsive motion of the two-component mixture in a rigid cylindrical vessel.

Characterising Dynamic Instability in High Water-Cut Oil-Water Flows Using High-Resolution Microwave Sensor Signals

NASA Astrophysics Data System (ADS)

Liu, Weixin; Jin, Ningde; Han, Yunfeng; Ma, Jing

2018-06-01

In the present study, multi-scale entropy algorithm was used to characterise the complex flow phenomena of turbulent droplets in high water-cut oil-water two-phase flow. First, we compared multi-scale weighted permutation entropy (MWPE), multi-scale approximate entropy (MAE), multi-scale sample entropy (MSE) and multi-scale complexity measure (MCM) for typical nonlinear systems. The results show that MWPE presents satisfied variability with scale and anti-noise ability. Accordingly, we conducted an experiment of vertical upward oil-water two-phase flow with high water-cut and collected the signals of a high-resolution microwave resonant sensor, based on which two indexes, the entropy rate and mean value of MWPE, were extracted. Besides, the effects of total flow rate and water-cut on these two indexes were analysed. Our researches show that MWPE is an effective method to uncover the dynamic instability of oil-water two-phase flow with high water-cut.

Microfluidic Impedance Flow Cytometry Enabling High-Throughput Single-Cell Electrical Property Characterization

PubMed Central

Chen, Jian; Xue, Chengcheng; Zhao, Yang; Chen, Deyong; Wu, Min-Hsien; Wang, Junbo

2015-01-01

This article reviews recent developments in microfluidic impedance flow cytometry for high-throughput electrical property characterization of single cells. Four major perspectives of microfluidic impedance flow cytometry for single-cell characterization are included in this review: (1) early developments of microfluidic impedance flow cytometry for single-cell electrical property characterization; (2) microfluidic impedance flow cytometry with enhanced sensitivity; (3) microfluidic impedance and optical flow cytometry for single-cell analysis and (4) integrated point of care system based on microfluidic impedance flow cytometry. We examine the advantages and limitations of each technique and discuss future research opportunities from the perspectives of both technical innovation and clinical applications. PMID:25938973

Experimental study of overland flow resistance coefficient model of grassland based on BP neural network

NASA Astrophysics Data System (ADS)

Jiao, Peng; Yang, Er; Ni, Yong Xin

2018-06-01

The overland flow resistance on grassland slope of 20° was studied by using simulated rainfall experiments. Model of overland flow resistance coefficient was established based on BP neural network. The input variations of model were rainfall intensity, flow velocity, water depth, and roughness of slope surface, and the output variations was overland flow resistance coefficient. Model was optimized by Genetic Algorithm. The results show that the model can be used to calculate overland flow resistance coefficient, and has high simulation accuracy. The average prediction error of the optimized model of test set is 8.02%, and the maximum prediction error was 18.34%.

Analysis of HRCT-derived xylem network reveals reverse flow in some vessels

USDA-ARS?s Scientific Manuscript database

Flow in xylem vessels is modeled based on constructions of three dimensional xylem networks derived from High Resolution Computed Tomography (HRCT) images of grapevine (Vitis vinifera) stems. Flow in 6-14% of the vessels was found to be oriented in the opposite direction to the bulk flow under norma...

A novel stationary phase derivatized from hydrophilic gigaporous polystyrene-based microspheres for high-speed protein chromatography.

PubMed

Qu, Jian-Bo; Wan, Xing-Zhong; Zhai, Yan-Qin; Zhou, Wei-Qing; Su, Zhi-Guo; Ma, Guang-Hui

2009-09-11

Using agarose coated gigaporous polystyrene microspheres as a base support, a novel anion exchanger (DEAE-AP) has been developed after functionalization with diethylaminoethyl chloride. The gigaporous structure, static adsorption behavior, and chromatographic properties of DEAE-AP medium were characterized and compared with those of commercially available resin DEAE Sepharose Fast Flow (DEAE-FF). The results implied that there existed some through pores in DEAE-AP microspheres, which effectively reduced resistance to stagnant mobile phase mass transfer by inducing convective flow of mobile phase in the gigapores of medium. As a consequence, the column packed with DEAE-AP exhibited low column backpressure, high column efficiency, high dynamic binding capacity and high protein resolution at high flow velocity up to 2600cm/h. In conclusion, all the results suggested that the gigaporous absorbent is promising for high-speed protein chromatography.

Method and apparatus for making articles from particle based materials

DOEpatents

Moorhead, A.J.; Menchhofer, P.A.

1995-12-19

A method and apparatus are disclosed for the production of articles made of a particle-based material; e.g., ceramics and sintered metals. In accordance with the invention, a thermally settable slurry containing a relatively high concentration of the particles is conveyed through an elongate flow area having a desired cross-sectional configuration. The slurry is heated as it is advanced through the flow area causing the slurry to set or harden in a shape which conforms to the cross-sectional configuration of the flow area. The material discharges from the flow area as a self-supporting solid of near net final dimensions. The article may then be sintered to consolidate the particles and provide a high density product. 10 figs.

Ultrasensitive SERS Flow Detector Using Hydrodynamic Focusing

PubMed Central

Negri, Pierre; Jacobs, Kevin T.; Dada, Oluwatosin O.; Schultz, Zachary D.

2013-01-01

Label-free, chemical specific detection in flow is important for high throughput characterization of analytes in applications such as flow injection analysis, electrophoresis, and chromatography. We have developed a surface-enhanced Raman scattering (SERS) flow detector capable of ultrasensitive optical detection on the millisecond time scale. The device employs hydrodynamic focusing to improve SERS detection in a flow channel where a sheath flow confines analyte molecules eluted from a fused silica capillary over a planar SERS-active substrate. Increased analyte interactions with the SERS substrate significantly improve detection sensitivity. The performance of this flow detector was investigated using a combination of finite element simulations, fluorescence imaging, and Raman experiments. Computational fluid dynamics based on finite element analysis was used to optimize the flow conditions. The modeling indicates that a number of factors, such as the capillary dimensions and the ratio of the sheath flow to analyte flow rates, are critical for obtaining optimal results. Sample confinement resulting from the flow dynamics was confirmed using wide-field fluorescence imaging of rhodamine 6G (R6G). Raman experiments at different sheath flow rates showed increased sensitivity compared with the modeling predictions, suggesting increased adsorption. Using a 50-millisecond acquisitions, a sheath flow rate of 180 μL/min, and a sample flow rate of 5 μL/min, a linear dynamic range from nanomolar to micromolar concentrations of R6G with a LOD of 1 nM is observed. At low analyte concentrations, rapid analyte desorption is observed, enabling repeated and high-throughput SERS detection. The flow detector offers substantial advantages over conventional SERS-based assays such as minimal sample volumes and high detection efficiency. PMID:24074461

Verification of a ground-based method for simulating high-altitude, supersonic flight conditions

NASA Astrophysics Data System (ADS)

Zhou, Xuewen; Xu, Jian; Lv, Shuiyan

Ground-based methods for accurately representing high-altitude, high-speed flight conditions have been an important research topic in the aerospace field. Based on an analysis of the requirements for high-altitude supersonic flight tests, a ground-based test bed was designed combining Laval nozzle, which is often found in wind tunnels, with a rocket sled system. Sled tests were used to verify the performance of the test bed. The test results indicated that the test bed produced a uniform-flow field with a static pressure and density equivalent to atmospheric conditions at an altitude of 13-15km and at a flow velocity of approximately M 2.4. This test method has the advantages of accuracy, fewer experimental limitations, and reusability.

Influence of the nuclear symmetry energy on the collective flows of charged pions

NASA Astrophysics Data System (ADS)

Gao, Yuan; Yong, Gao-Chan; Zhang, Lei; Zuo, Wei

2018-01-01

Based on the isospin-dependent Boltzmann-Uehling-Uhlenbeck (IBUU) transport model, we studied charged pion transverse and elliptic flows in semicentral 197Au+197Au collisions at 600 MeV/nucleon. It is found that π+-π- differential transverse flow and the difference of π+ and π- transverse flows almost show no effects of the symmetry energy. Their corresponding elliptic flows are largely affected by the symmetry energy, especially at high transverse momenta. The isospin-dependent pion elliptic flow at high transverse momenta thus provides a promising way to probe the high-density behavior of the symmetry energy in heavy-ion collisions at the Facility for Antiproton and Ion Research (FAIR) at GSI, Darmstadt or at the Cooling Storage Ring (CSR) at HIRFL, Lanzhou.

Ground Based Studies of Gas-Liquid Flows in Microgravity Using Learjet Trajectories

NASA Technical Reports Server (NTRS)

Bousman, W. S.; Dukler, A. E.

1994-01-01

A 1.27 cm diameter two phase gas-liquid flow experiment has been developed with the NASA Lewis Research Center to study two-phase flows in microgravity. The experiment allows for the measurement of void fraction, pressure drop, film thickness and bubble and wave velocities as well as for high speed photography. Three liquids were used to study the effects of liquid viscosity and surface tension, and flow pattern maps are presented for each. The experimental results are used to develop mechanistically based models to predict void fraction, bubble velocity, pressure drop and flow pattern transitions in microgravity.

Multiplexed and Microparticle-based Analyses: Quantitative Tools for the Large-Scale Analysis of Biological Systems

PubMed Central

Nolan, John P.; Mandy, Francis

2008-01-01

While the term flow cytometry refers to the measurement of cells, the approach of making sensitive multiparameter optical measurements in a flowing sample stream is a very general analytical approach. The past few years have seen an explosion in the application of flow cytometry technology for molecular analysis and measurements using micro-particles as solid supports. While microsphere-based molecular analyses using flow cytometry date back three decades, the need for highly parallel quantitative molecular measurements that has arisen from various genomic and proteomic advances has driven the development in particle encoding technology to enable highly multiplexed assays. Multiplexed particle-based immunoassays are now common place, and new assays to study genes, protein function, and molecular assembly. Numerous efforts are underway to extend the multiplexing capabilities of microparticle-based assays through new approaches to particle encoding and analyte reporting. The impact of these developments will be seen in the basic research and clinical laboratories, as well as in drug development. PMID:16604537

High Fidelity Simulations of Unsteady Flow through Turbopumps and Flowliners

NASA Technical Reports Server (NTRS)

Kiris, Cetin C.; Kwak, dochan; Chan, William; Housman, Jeff

2006-01-01

High fidelity computations were carried out to analyze the orbiter LH2 feedline flowliner. Computations were performed on the Columbia platform which is a 10,240-processor supercluster consisting of 20 Altix nodes with 512 processor each. Various computational models were used to characterize the unsteady flow features in the turbopump, including the orbiter Low-Pressure-Fuel-Turbopump (LPFTP) inducer, the orbiter manifold and a test article used to represent the manifold. Unsteady flow originating from the orbiter LPFTP inducer is one of the major contributors to the high frequency cyclic loading that results in high cycle fatigue damage to the gimbal flowliners just upstream of the LPFTP. The flow fields for the orbiter manifold and representative test article are computed and analyzed for similarities and differences. The incompressible Navier-Stokes flow solver INS3D, based on the artificial compressibility method, was used to compute the flow of liquid hydrogen in each test article.

Can hydraulic-modelled rating curves reduce uncertainty in high flow data?

NASA Astrophysics Data System (ADS)

Westerberg, Ida; Lam, Norris; Lyon, Steve W.

2017-04-01

Flood risk assessments rely on accurate discharge data records. Establishing a reliable rating curve for calculating discharge from stage at a gauging station normally takes years of data collection efforts. Estimation of high flows is particularly difficult as high flows occur rarely and are often practically difficult to gauge. Hydraulically-modelled rating curves can be derived based on as few as two concurrent stage-discharge and water-surface slope measurements at different flow conditions. This means that a reliable rating curve can, potentially, be derived much faster than a traditional rating curve based on numerous stage-discharge gaugings. In this study we compared the uncertainty in discharge data that resulted from these two rating curve modelling approaches. We applied both methods to a Swedish catchment, accounting for uncertainties in the stage-discharge gauging and water-surface slope data for the hydraulic model and in the stage-discharge gauging data and rating-curve parameters for the traditional method. We focused our analyses on high-flow uncertainty and the factors that could reduce this uncertainty. In particular, we investigated which data uncertainties were most important, and at what flow conditions the gaugings should preferably be taken. First results show that the hydraulically-modelled rating curves were more sensitive to uncertainties in the calibration measurements of discharge than water surface slope. The uncertainty of the hydraulically-modelled rating curves were lowest within the range of the three calibration stage-discharge gaugings (i.e. between median and two-times median flow) whereas uncertainties were higher outside of this range. For instance, at the highest observed stage of the 24-year stage record, the 90% uncertainty band was -15% to +40% of the official rating curve. Additional gaugings at high flows (i.e. four to five times median flow) would likely substantially reduce those uncertainties. These first results show the potential of the hydraulically-modelled curves, particularly where the calibration gaugings are of high quality and cover a wide range of flow conditions.

Fiber-optic-based laser vapor screen flow visualization system for aerodynamic research in larger scale subsonic and transonic wind tunnels

NASA Technical Reports Server (NTRS)

Erickson, Gary E.; Inenaga, Andrew S.

1994-01-01

Laser vapor screen (LVS) flow visualization systems that are fiber-optic based were developed and installed for aerodynamic research in the Langley 8-Foot Transonic Pressure Tunnel and the Langley 7- by 10-Foot High Speed Tunnel. Fiber optics are used to deliver the laser beam through the plenum shell that surrounds the test section of each facility and to the light-sheet-generating optics positioned in the ceiling window of the test section. Water is injected into the wind tunnel diffuser section to increase the relative humidity and promote condensation of the water vapor in the flow field about the model. The condensed water vapor is then illuminated with an intense sheet of laser light to reveal features of the flow field. The plenum shells are optically sealed; therefore, video-based systems are used to observe and document the flow field. Operational experience shows that the fiber-optic-based systems provide safe, reliable, and high-quality off-surface flow visualization in smaller and larger scale subsonic and transonic wind tunnels. The design, the installation, and the application of the Langley Research Center (LaRC) LVS flow visualization systems in larger scale wind tunnels are highlighted. The efficiency of the fiber optic LVS systems and their insensitivity to wind tunnel vibration, the tunnel operating temperature and pressure variations, and the airborne contaminants are discussed.

The critical role of uncertainty in projections of hydrological extremes

NASA Astrophysics Data System (ADS)

Meresa, Hadush K.; Romanowicz, Renata J.

2017-08-01

This paper aims to quantify the uncertainty in projections of future hydrological extremes in the Biala Tarnowska River at Koszyce gauging station, south Poland. The approach followed is based on several climate projections obtained from the EURO-CORDEX initiative, raw and bias-corrected realizations of catchment precipitation, and flow simulations derived using multiple hydrological model parameter sets. The projections cover the 21st century. Three sources of uncertainty are considered: one related to climate projection ensemble spread, the second related to the uncertainty in hydrological model parameters and the third related to the error in fitting theoretical distribution models to annual extreme flow series. The uncertainty of projected extreme indices related to hydrological model parameters was conditioned on flow observations from the reference period using the generalized likelihood uncertainty estimation (GLUE) approach, with separate criteria for high- and low-flow extremes. Extreme (low and high) flow quantiles were estimated using the generalized extreme value (GEV) distribution at different return periods and were based on two different lengths of the flow time series. A sensitivity analysis based on the analysis of variance (ANOVA) shows that the uncertainty introduced by the hydrological model parameters can be larger than the climate model variability and the distribution fit uncertainty for the low-flow extremes whilst for the high-flow extremes higher uncertainty is observed from climate models than from hydrological parameter and distribution fit uncertainties. This implies that ignoring one of the three uncertainty sources may cause great risk to future hydrological extreme adaptations and water resource planning and management.

Modeling the hydrodynamic and electrochemical efficiency of semi-solid flow batteries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brunini, VE; Chiang, YM; Carter, WC

2012-05-01

A mathematical model of flow cell operation incorporating hydrodynamic and electrochemical effects in three dimensions is developed. The model and resulting simulations apply to recently demonstrated high energy-density semi-solid flow cells. In particular, state of charge gradients that develop during low flow rate operation and their effects on the spatial non-uniformity of current density within flow cells are quantified. A one-dimensional scaling model is also developed and compared to the full three-dimensional simulation. The models are used to demonstrate the impact of the choice of electrochemical couple on flow cell performance. For semi-solid flow electrodes, which can use solid activemore » materials with a wide variety of voltage-capacity responses, we find that cell efficiency is maximized for electrochemical couples that have a relatively flat voltage vs. capacity curve, operated under slow flow conditions. For example, in flow electrodes limited by macroscopic charge transport, an LiFePO4-based system requires one-third the polarization to reach the same cycling rate as an LiCoO2-based system, all else being equal. Our conclusions are generally applicable to high energy density flow battery systems, in which flow rates can be comparatively low for a given required power. (C) 2012 Elsevier Ltd. All rights reserved.« less

Evaluation of particle-based flow characteristics using novel Eulerian indices

NASA Astrophysics Data System (ADS)

Cho, Youngmoon; Kang, Seongwon

2017-11-01

The main objective of this study is to evaluate flow characteristics in complex particle-laden flows efficiently using novel Eulerian indices. For flows with a large number of particles, a Lagrangian approach leads to accurate yet inefficient prediction in many engineering problems. We propose a technique based on Eulerian transport equation and ensemble-averaged particle properties, which enables efficient evaluation of various particle-based flow characteristics such as the residence time, accumulated travel distance, mean radial force, etc. As a verification study, we compare the developed Eulerian indices with those using Lagrangian approaches for laminar flows with and without a swirling motion and density ratio. The results show satisfactory agreement between two approaches. The accumulated travel distance is modified to analyze flow motions inside IC engines and, when applied to flow bench cases, it can predict swirling and tumbling motions successfully. For flows inside a cyclone separator, the mean radial force is applied to predict the separation of particles and is shown to have a high correlation to the separation efficiency for various working conditions. In conclusion, the proposed Eulerian indices are shown to be useful tools to analyze complex particle-based flow characteristics. Corresponding author.

Flow restrictor silicon membrane microvalve actuated by optically controlled paraffin phase transition

NASA Astrophysics Data System (ADS)

Kolari, K.; Havia, T.; Stuns, I.; Hjort, K.

2014-08-01

Restrictor valves allow proportional control of fluid flow but are rarely integrated in microfluidic systems. In this study, an optically actuated silicon membrane restrictor microvalve is demonstrated. Its actuation is based on the phase transition of paraffin, using a paraffin wax mixed with a suitable concentration of optically absorbing nanographite particles. Backing up the membrane with oil (the melted paraffin) allows for a compliant yet strong contact to the valve seat, which enables handling of high pressures. At flow rates up to 30 µL min-1 and at a pressure of 2 bars, the valve can successfully be closed and control the flow level by restriction. The use of this paraffin composite as an adhesive layer sandwiched between the silicon valve and glass eases fabrication. This type of restrictor valve is best suited for high pressure, low volume flow silicon-based nanofluidic systems.

A MEMS-based Air Flow Sensor with a Free-standing Micro-cantilever Structure

PubMed Central

Wang, Yu-Hsiang; Lee, Chia-Yen; Chiang, Che-Ming

2007-01-01

This paper presents a micro-scale air flow sensor based on a free-standing cantilever structure. In the fabrication process, MEMS techniques are used to deposit a silicon nitride layer on a silicon wafer. A platinum layer is deposited on the silicon nitride layer to form a piezoresistor, and the resulting structure is then etched to create a freestanding micro-cantilever. When an air flow passes over the surface of the cantilever beam, the beam deflects in the downward direction, resulting in a small variation in the resistance of the piezoelectric layer. The air flow velocity is determined by measuring the change in resistance using an external LCR meter. The experimental results indicate that the flow sensor has a high sensitivity (0.0284 Ω/ms-1), a high velocity measurement limit (45 ms-1) and a rapid response time (0.53 s). PMID:28903233

Viscous investigation of a flapping foil propulsor

NASA Astrophysics Data System (ADS)

Posri, Attapol; Phoemsapthawee, Surasak; Thaweewat, Nonthipat

2018-01-01

Inspired by how fishes propel themselves, a flapping-foil device is invented as an alternative propulsion system for ships and boats. The performance of such propulsor has been formerly investigated using a potential flow code. The simulation results have shown that the device has high propulsive efficiency over a wide range of operation. However, the potential flow gives good results only when flow separation is not present. In case of high flapping frequency, the flow separation can occur over a short instant due to fluid viscosity and high angle of attack. This may cause a reduction of propulsive efficiency. A commercial CFD code based on Lattice Boltzmann Method, XFlow, is then employed in order to investigate the viscous effect over the propulsive performance of the flapping foil. The viscous results agree well with the potential flow results, confirming the high efficiency of the propulsor. As expected, viscous results show lower efficiency in high flapping frequency zone.

Multi-phase imaging of intermittency at steady state using differential imaging method by X-ray micro-tomography

NASA Astrophysics Data System (ADS)

Gao, Y.; Lin, Q.; Bijeljic, B.; Blunt, M. J.

2017-12-01

To observe intermittency in consolidated rock, we image a steady state flow of brine and decane in Bentheimer sandstone. We devise an experimental method based on X-ray differential imaging method to examine how changes in flow rate impact the pore-scale distribution of fluids during co-injection flow under dynamic flow conditions at steady state. This helps us elucidate the diverse flow regimes (connected, intermittent break-up, or continual break-up of the non-wetting phase pathways) for two capillary numbers. Also, relative permeability curves under both capillary and viscous limited conditions could be measured. We have performed imbibition sample floods using oil-brine and measured steady state relative permeability on a sandstone rock core in order to fully characterize the flow behaviour at low and high Ca. Two sets of experiments at high and low flow rates are provided to explore the time-evolution of the non-wetting phase clusters distribution under different flow conditions. The high flow rate is 0.5 mL/min, whose corresponding capillary number is 7.7×10-6. The low flow rate is 0.02 mL/min, whose capillary number is 3.1×10-7. A procedure based on using high-salinity brine as the contrast phase and applying differential imaging between the dry scan and that of the sample saturation with a 30 wt% Potassium iodide (KI) doped brine help to make sure there is no non-wetting phase in micro-pores. Then the intermittent phase in multiphase flow image at high Ca can be quantified by obtaining the differential image between the 30 wt% KI brine image and the scans that taken at each fixed fractional flow. By using the grey scale histogram distribution of the raw images at each condition, the oil proportion in the intermittent phase can be calculated. The pressure drops at each fractional flow at low and high Ca can be measured by high-precision pressure differential sensors and utilized to calculate to the relative permeability at pore scale. The relative permeability data and fw-Sw relationship obtained by our experiment at pore scale are compared with the data collected from experiments which were conducted at core scale, and they match well.

Pressure-based high-order TVD methodology for dynamic stall control

NASA Astrophysics Data System (ADS)

Yang, H. Q.; Przekwas, A. J.

1992-01-01

The quantitative prediction of the dynamics of separating unsteady flows, such as dynamic stall, is of crucial importance. This six-month SBIR Phase 1 study has developed several new pressure-based methodologies for solving 3D Navier-Stokes equations in both stationary and moving (body-comforting) coordinates. The present pressure-based algorithm is equally efficient for low speed incompressible flows and high speed compressible flows. The discretization of convective terms by the presently developed high-order TVD schemes requires no artificial dissipation and can properly resolve the concentrated vortices in the wing-body with minimum numerical diffusion. It is demonstrated that the proposed Newton's iteration technique not only increases the convergence rate but also strongly couples the iteration between pressure and velocities. The proposed hyperbolization of the pressure correction equation is shown to increase the solver's efficiency. The above proposed methodologies were implemented in an existing CFD code, REFLEQS. The modified code was used to simulate both static and dynamic stalls on two- and three-dimensional wing-body configurations. Three-dimensional effect and flow physics are discussed.

Fast cholesterol detection using flow injection microfluidic device with functionalized carbon nanotubes based electrochemical sensor.

PubMed

Wisitsoraat, A; Sritongkham, P; Karuwan, C; Phokharatkul, D; Maturos, T; Tuantranont, A

2010-12-15

This work reports a new cholesterol detection scheme using functionalized carbon nanotube (CNT) electrode in a polydimethylsiloxane/glass based flow injection microfluidic chip. CNTs working, silver reference and platinum counter electrode layers were fabricated on the chip by sputtering and low temperature chemical vapor deposition methods. Cholesterol oxidase prepared in polyvinyl alcohol solution was immobilized on CNTs by in-channel flow technique. Cholesterol analysis based on flow injection chronoamperometric measurement was performed in 150-μm-wide and 150-μm-deep microchannels. Fast and sensitive real-time detection was achieved with high throughput of more than 60 samples per hour and small sample volume of 15 μl. The cholesterol sensor had a linear detection range between 50 and 400 mg/dl. In addition, low cross-sensitivities toward glucose, ascorbic acid, acetaminophen and uric acid were confirmed. The proposed system is promising for clinical diagnostics of cholesterol with high speed real-time detection capability, very low sample consumption, high sensitivity, low interference and good stability. Copyright © 2010 Elsevier B.V. All rights reserved.

High-repetition-rate interferometric Rayleigh scattering for flow-velocity measurements

NASA Astrophysics Data System (ADS)

Estevadeordal, Jordi; Jiang, Naibo; Cutler, Andrew D.; Felver, Josef J.; Slipchenko, Mikhail N.; Danehy, Paul M.; Gord, James R.; Roy, Sukesh

2018-03-01

High-repetition-rate interferometric-Rayleigh-scattering (IRS) velocimetry is demonstrated for non-intrusive, high-speed flow-velocity measurements. High temporal resolution is obtained with a quasi-continuous burst-mode laser that is capable of operating at 10-100 kHz, providing 10-ms bursts with pulse widths of 5-1000 ns and pulse energy > 100 mJ at 532 nm. Coupled with a high-speed camera system, the IRS method is based on imaging the flow field through an etalon with 8-GHz free spectral range and capturing the Doppler shift of the Rayleigh-scattered light from the flow at multiple points having constructive interference. The seed-laser linewidth permits a laser linewidth of < 150 MHz at 532 nm. The technique is demonstrated in a high-speed jet, and high-repetition-rate image sequences are shown.

High-Fidelity Geometric Modeling and Mesh Generation for Mechanics Characterization of Polycrystalline Materials

DTIC Science & Technology

2014-10-26

From the parameterization results, we extract adaptive and anisotropic T-meshes for the further T- spline surface construction. Finally, a gradient flow...field-based method [7, 12] to generate adaptive and anisotropic quadrilateral meshes, which can be used as the control mesh for high-order T- spline ...parameterization results, we extract adaptive and anisotropic T-meshes for the further T- spline surface construction. Finally, a gradient flow-based

Development of a diffraction imaging flow cytometer

PubMed Central

Jacobs, Kenneth M.; Lu, Jun Q.

2013-01-01

Diffraction images record angle-resolved distribution of scattered light from a particle excited by coherent light and can correlate highly with the 3D morphology of a particle. We present a jet-in-fluid design of flow chamber for acquisition of clear diffraction images in a laminar flow. Diffraction images of polystyrene spheres of different diameters were acquired and found to correlate highly with the calculated ones based on the Mie theory. Fast Fourier transform analysis indicated that the measured images can be used to extract sphere diameter values. These results demonstrate the significant potentials of high-throughput diffraction imaging flow cytometry for extracting 3D morphological features of cells. PMID:19794790

Flow control of a centrifugal fan in a commercial air conditioner

NASA Astrophysics Data System (ADS)

Kim, Jiyu; Bang, Kyeongtae; Choi, Haecheon; Seo, Eung Ryeol; Kang, Yonghun

2015-11-01

Air-conditioning fans require a low noise level to provide user comfort and quietness. The aerodynamic noise sources are generated by highly unsteady, turbulent structures near the fan blade. In this study, we investigate the flow characteristics of a centrifugal fan in an air-conditioner indoor unit and suggest control ideas to develop a low noise fan. The experiment is conducted at the operation condition where the Reynolds number is 163000 based on the blade tip velocity and chord length. Intermittent separation occurs at the blade leading edge and thus flow significantly fluctuates there, whereas vortex shedding occurs at the blade trailing edge. Furthermore, the discharge flow observed in the axial plane near the shroud shows low-frequency intermittent behaviors, resulting in high Reynolds stresses. To control these flow structures, we modify the shapes of the blade leading edge and shroud of the centrifugal fan and obtain noise reduction. The flow characteristics of the base and modified fans will be discussed. Supported by 0420-20130051.

Lithium-Based High Energy Density Flow Batteries

NASA Technical Reports Server (NTRS)

Bugga, Ratnakumar V. (Inventor); West, William C. (Inventor); Kindler, Andrew (Inventor); Smart, Marshall C. (Inventor)

2014-01-01

Systems and methods in accordance with embodiments of the invention implement a lithium-based high energy density flow battery. In one embodiment, a lithium-based high energy density flow battery includes a first anodic conductive solution that includes a lithium polyaromatic hydrocarbon complex dissolved in a solvent, a second cathodic conductive solution that includes a cathodic complex dissolved in a solvent, a solid lithium ion conductor disposed so as to separate the first solution from the second solution, such that the first conductive solution, the second conductive solution, and the solid lithium ionic conductor define a circuit, where when the circuit is closed, lithium from the lithium polyaromatic hydrocarbon complex in the first conductive solution dissociates from the lithium polyaromatic hydrocarbon complex, migrates through the solid lithium ionic conductor, and associates with the cathodic complex of the second conductive solution, and a current is generated.

High-speed Particle Image Velocimetry Near Surfaces

PubMed Central

Lu, Louise; Sick, Volker

2013-01-01

Multi-dimensional and transient flows play a key role in many areas of science, engineering, and health sciences but are often not well understood. The complex nature of these flows may be studied using particle image velocimetry (PIV), a laser-based imaging technique for optically accessible flows. Though many forms of PIV exist that extend the technique beyond the original planar two-component velocity measurement capabilities, the basic PIV system consists of a light source (laser), a camera, tracer particles, and analysis algorithms. The imaging and recording parameters, the light source, and the algorithms are adjusted to optimize the recording for the flow of interest and obtain valid velocity data. Common PIV investigations measure two-component velocities in a plane at a few frames per second. However, recent developments in instrumentation have facilitated high-frame rate (> 1 kHz) measurements capable of resolving transient flows with high temporal resolution. Therefore, high-frame rate measurements have enabled investigations on the evolution of the structure and dynamics of highly transient flows. These investigations play a critical role in understanding the fundamental physics of complex flows. A detailed description for performing high-resolution, high-speed planar PIV to study a transient flow near the surface of a flat plate is presented here. Details for adjusting the parameter constraints such as image and recording properties, the laser sheet properties, and processing algorithms to adapt PIV for any flow of interest are included. PMID:23851899

Construction and evaluation of a capillary array DNA sequencer based on a micromachined sheath-flow cuvette.

PubMed

Crabtree, H J; Bay, S J; Lewis, D F; Zhang, J; Coulson, L D; Fitzpatrick, G A; Delinger, S L; Harrison, D J; Dovichi, N J

2000-04-01

A capillary array electrophoresis DNA sequencer is reported based on a micromachined sheath-flow cuvette as the detection chamber. This cuvette is equipped with a set of micromachined features that hold the capillaries in precise registration to ensure uniform spacing between the capillaries, in order to generate uniform hydrodynamic flow in the cuvette. A laser beam excites all of the samples simultaneously, and a microscope objective images fluorescence onto a set of avalanche photodiodes, which operate in the analog mode. A high-gain transimpedance amplifier is used for each photodiode, providing high duty-cycle detection of fluorescence.

Chemical Vapor Deposition at High Pressure in a Microgravity Environment

NASA Technical Reports Server (NTRS)

McCall, Sonya; Bachmann, Klaus; LeSure, Stacie; Sukidi, Nkadi; Wang, Fuchao

1999-01-01

In this paper we present an evaluation of critical requirements of organometallic chemical vapor deposition (OMCVD) at elevated pressure for a channel flow reactor in a microgravity environment. The objective of using high pressure is to maintain single-phase surface composition for materials that have high thermal decomposition pressure at their optimum growth temperature. Access to microgravity is needed to maintain conditions of laminar flow, which is essential for process analysis. Based on ground based observations we present an optimized reactor design for OMCVD at high pressure and reduced gravity. Also, we discuss non-intrusive real-time optical monitoring of flow dynamics coupled to homogeneous gas phase reactions, transport and surface processes. While suborbital flights may suffice for studies of initial stages of heteroepitaxy experiments in space are essential for a complete evaluation of steady-state growth.

Experimental study on rotating instability mode characteristics of axial compressor tip flow

NASA Astrophysics Data System (ADS)

Tian, Jie; Yao, Dan; Wu, Yadong; Ouyang, Hua

2018-04-01

This paper investigates the rotating instabilities that occurred on the single-stage axial compressor designed for aerodynamic performance validation, which was tested with two sets of circumferential measuring points in combination. Circumferential mode characteristics of compressors are usually too high to be captured experimentally, and aliasing of the circumferential mode order occurs when not enough sensors are used. A calibration and prediction method to capture the higher circumferential mode of unsteady flow in a compressor was proposed. Unsteady pressure fluctuations near the tip region in an axial compressor were studied, and high circumferential mode characteristics were captured on both the blade passing frequency (BPF) and the rotational instability frequency (RIF) under different flow rate conditions based on this novel method. The characteristic RI spectrum with a broadband hump was present in a large range of flow conditions. Both the frequency range and the dominant circumferential mode order decreased as the flow rate decreased. Based on the calibrated mode characteristics, a rotating aerodynamic source model is used to explain the side-by-side peak of RIF spectrum and rotating characteristics of RI. The calibration and prediction method of the high circumferential mode is beneficial for the research of unsteady flow in an axial compressor.

Study on the flow nonuniformity in a high capacity Stirling pulse tube cryocooler

NASA Astrophysics Data System (ADS)

You, X.; Zhi, X.; Duan, C.; Jiang, X.; Qiu, L.; Li, J.

2017-12-01

High capacity Stirling-type pulse tube cryocoolers (SPTC) have promising applications in high temperature superconductive motor and gas liquefaction. However, with the increase of cooling capacity, its performance deviates from well-accepted one-dimensional model simulation, such as Sage and Regen, mainly due to the strong field nonuniformity. In this study, several flow straighteners placed at both ends of the pulse tube are investigated to improve the flow distribution. A two-dimensional model of the pulse tube based on the computational fluid dynamics (CFD) method has been built to study the flow distribution of the pulse tube with different flow straighteners including copper screens, copper slots, taper transition and taper stainless slot. A SPTC set-up which has more than one hundred Watts cooling power at 80 K has been built and tested. The flow straighteners mentioned above have been applied and tested. The results show that with the best flow straightener the cooling performance of the SPTC can be significantly improved. Both CFD simulation and experiment show that the straighteners have impacts on the flow distribution and the performance of the high capacity SPTC.

Sublingual microcirculatory blood flow and vessel density in Sherpas at high altitude

PubMed Central

Coppel, Jonny; Court, Jo; van der Kaaij, Jildou; Vercueil, Andre; Feelisch, Martin; Levett, Denny; Mythen, Monty; Grocott, Michael P.; Martin, Daniel

2017-01-01

Anecdotal reports suggest that Sherpa highlanders demonstrate extraordinary tolerance to hypoxia at high altitude, despite exhibiting lower arterial oxygen content than acclimatized lowlanders. This study tested the hypothesis that Sherpas exposed to hypobaric hypoxia on ascent to 5,300 m develop increased microcirculatory blood flow as a means of maintaining tissue oxygen delivery. Incident dark-field imaging was used to obtain images of the sublingual microcirculation from 64 Sherpas and 69 lowlanders. Serial measurements were obtained from participants undertaking an ascent from baseline testing (35 m or 1,300 m) to Everest base camp (5,300 m) and following subsequent descent in Kathmandu (1,300 m). Microcirculatory flow index and heterogeneity index were used to provide indexes of microcirculatory flow, while capillary density was assessed using small vessel density. Sherpas demonstrated significantly greater microcirculatory blood flow at Everest base camp, but not at baseline testing or on return in Kathmandu, than lowlanders. Additionally, blood flow exhibited greater homogeneity at 5,300 and 1,300 m (descent) in Sherpas than lowlanders. Sublingual small vessel density was not different between the two cohorts at baseline testing or at 1,300 m; however, at 5,300 m, capillary density was up to 30% greater in Sherpas. These data suggest that Sherpas can maintain a significantly greater microcirculatory flow per unit time and flow per unit volume of tissue at high altitude than lowlanders. These findings support the notion that peripheral vascular factors at the microcirculatory level may be important in the process of adaptation to hypoxia. NEW & NOTEWORTHY Sherpa highlanders demonstrate extraordinary tolerance to hypoxia at high altitude, yet the physiological mechanisms underlying this tolerance remain unknown. In our prospective study, conducted on healthy volunteers ascending to Everest base camp (5,300 m), we demonstrated that Sherpas have a higher sublingual microcirculatory blood flow and greater capillary density at high altitude than lowlanders. These findings support the notion that the peripheral microcirculation plays a key role in the process of long-term adaptation to hypoxia. PMID:28126908

Arsine flow requirement for the flow modulation growth of high purity GaAs using adduct-grade triethylgallium

NASA Astrophysics Data System (ADS)

Pitts, B. L.; Emerson, D. T.; Shealy, J. R.

1992-10-01

Using arsine and triethylgallium with flow modulation, organometallic vapor phase epitaxy can produce high purity GaAs layers with V/III molar ratios near unity. We have estimated that under appropriate growth conditions the arsine incorporation efficiency into epitaxial GaAs can exceed 30%. The arsine flow requirement for obtaining good morphology has been identified over a range of substrate temperatures using adduct-grade triethylgallium. The process described reduces the environmental impact and life safety risk of the hydride based organometallic vapor phase epitaxial method.

Numerical Analysis of Base Flowfield for a Four-Engine Clustered Nozzle Configuration

NASA Technical Reports Server (NTRS)

Wang, Ten-See

1995-01-01

Excessive base heating has been a problem for many launch vehicles. For certain designs such as the direct dump of turbine exhaust inside and at the lip of the nozzle, the potential burning of the turbine exhaust in the base region can be of great concern. Accurate prediction of the base environment at altitudes is therefore very important during the vehicle design phase. Otherwise, undesirable consequences may occur. In this study, the turbulent base flowfield of a cold flow experimental investigation for a four-engine clustered nozzle was numerically benchmarked using a pressure-based computational fluid dynamics (CFD) method. This is a necessary step before the benchmarking of hot flow and combustion flow tests can be considered. Since the medium was unheated air, reasonable prediction of the base pressure distribution at high altitude was the main goal. Several physical phenomena pertaining to the multiengine clustered nozzle base flow physics were deduced from the analysis.

A high-energy-density redox flow battery based on zinc/polyhalide chemistry.

PubMed

Zhang, Liqun; Lai, Qinzhi; Zhang, Jianlu; Zhang, Huamin

2012-05-01

Zn and the Art of Battery Development: A zinc/polyhalide redox flow battery employs Br(-) /ClBr(2-) and Zn/Zn(2+) redox couples in its positive and negative half-cells, respectively. The performance of the battery is evaluated by charge-discharge cycling tests and reveals a high energy efficiency of 81%, based on a Coulombic efficiency of 96% and voltage efficiency of 84%. The new battery technology can provide high performance and energy density at an acceptable cost. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

A High-Resolution Godunov Method for Compressible Multi-Material Flow on Overlapping Grids

DOE Office of Scientific and Technical Information (OSTI.GOV)

Banks, J W; Schwendeman, D W; Kapila, A K

2006-02-13

A numerical method is described for inviscid, compressible, multi-material flow in two space dimensions. The flow is governed by the multi-material Euler equations with a general mixture equation of state. Composite overlapping grids are used to handle complex flow geometry and block-structured adaptive mesh refinement (AMR) is used to locally increase grid resolution near shocks and material interfaces. The discretization of the governing equations is based on a high-resolution Godunov method, but includes an energy correction designed to suppress numerical errors that develop near a material interface for standard, conservative shock-capturing schemes. The energy correction is constructed based on amore » uniform pressure-velocity flow and is significant only near the captured interface. A variety of two-material flows are presented to verify the accuracy of the numerical approach and to illustrate its use. These flows assume an equation of state for the mixture based on Jones-Wilkins-Lee (JWL) forms for the components. This equation of state includes a mixture of ideal gases as a special case. Flow problems considered include unsteady one-dimensional shock-interface collision, steady interaction of an planar interface and an oblique shock, planar shock interaction with a collection of gas-filled cylindrical inhomogeneities, and the impulsive motion of the two-component mixture in a rigid cylindrical vessel.« less

Report on Technology Horizons: A Vision for Air Force Science and Technology During 2010-2030. Volume 1

DTIC Science & Technology

2010-05-15

flow and decision processes across the air and space domains. It thus comprises traditional wired and fiber-optic computer networks based on...dual flow path design allow high volumetric efficiency, and high cruise speed provides significantly increased survivability. Vertical takeoff...emerging “third-stream engine architectures” can enable for constant mass flow engines that can provide further reductions in fuel consumption. A wide

Numerical Simulation of Non-Rotating and Rotating Coolant Channel Flow Fields. Part 1

NASA Technical Reports Server (NTRS)

Rigby, David L.

2000-01-01

Future generations of ultra high bypass-ratio jet engines will require far higher pressure ratios and operating temperatures than those of current engines. For the foreseeable future, engine materials will not be able to withstand the high temperatures without some form of cooling. In particular the turbine blades, which are under high thermal as well as mechanical loads, must be cooled. Cooling of turbine blades is achieved by bleeding air from the compressor stage of the engine through complicated internal passages in the turbine blades (internal cooling, including jet-impingement cooling) and by bleeding small amounts of air into the boundary layer of the external flow through small discrete holes on the surface of the blade (film cooling and transpiration cooling). The cooling must be done using a minimum amount of air or any increases in efficiency gained through higher operating temperature will be lost due to added load on the compressor stage. Turbine cooling schemes have traditionally been based on extensive empirical data bases, quasi-one-dimensional computational fluid dynamics (CFD) analysis, and trial and error. With improved capabilities of CFD, these traditional methods can be augmented by full three-dimensional simulations of the coolant flow to predict in detail the heat transfer and metal temperatures. Several aspects of turbine coolant flows make such application of CFD difficult, thus a highly effective CFD methodology must be used. First, high resolution of the flow field is required to attain the needed accuracy for heat transfer predictions, making highly efficient flow solvers essential for such computations. Second, the geometries of the flow passages are complicated but must be modeled accurately in order to capture all important details of the flow. This makes grid generation and grid quality important issues. Finally, since coolant flows are turbulent and separated the effects of turbulence must be modeled with a low Reynolds number turbulence model to accurately predict details of heat transfer.

Unsteady Analysis of Turbine Main Flow Coupled with Secondary Air Flow

NASA Technical Reports Server (NTRS)

Hah, Chunill

2006-01-01

Two numerical approaches are used to model the interaction between the turbine main gas flow and the wheelspace cavity seal flow. The 3-D, unsteady Reynolds-averaged Navier-Stokes equations are solved with a CFD code based on a structured grid to study the interaction between the turbine main gas flow and the wheelspace cavity seal flow. A CFD code based on an unstructured grid is used to solve detailed flow feature in the cavity seal which has a complex geometry. The numerical results confirm various observations from earlier experimental studies under similar flow conditions. When the flow rate through the rim cavity seal is increased, the ingestion of the main turbine flow into the rim seal area decreases drastically. However, a small amount of main gas flow is ingested to the rim seal area even with very high level of seal flow rate. This is due to the complex nature of 3-D, unsteady flow interaction near the hub of the turbine stage.

Highly sensitive determination of cadmium and lead using a low-cost electrochemical flow-through cell based on a carbon paste electrode.

PubMed

Wonsawat, Wanida; Dungchai, Wijitar; Motomizu, Shoji; Chuanuwatanakul, Suchada; Chailapakul, Orawon

2012-01-01

A low-cost thin-layer electrochemical flow-through cell based on a carbon paste electrode (CPE), was constructed for the highly sensitive determination of cadmium(II) (Cd(2+)) and lead(II) (Pb(2+)) ions. The sensitivity of the proposed cell for Cd(2+) and Pb(2+) ion detection was improved by using the smallest channel height without the need for any complicated electrode modification. Under the optimum conditions, the detection limits of Cd(2+) and Pb(2+) ions (0.08 and 0.07 µg dm(-3), respectively) were 13.8- and 11.4-fold lower than that of a commercial flow cell (1.1 and 0.8 µg dm(-3), respectively). Moreover, the percentage recoveries of Cd(2+) and Pb(2+) for the in-house designed thin-layer flow cell were higher than those for the commercially available cell in all tested water samples, and within the acceptable range. The proposed flow cell is promising as an inexpensive and alternative one for the highly sensitive monitoring of heavy metal ions. 2012 © The Japan Society for Analytical Chemistry

Development and simulation of microfluidic Wheatstone bridge for high-precision sensor

NASA Astrophysics Data System (ADS)

Shipulya, N. D.; Konakov, S. A.; Krzhizhanovskaya, V. V.

2016-08-01

In this work we present the results of analytical modeling and 3D computer simulation of microfluidic Wheatstone bridge, which is used for high-accuracy measurements and precision instruments. We propose and simulate a new method of a bridge balancing process by changing the microchannel geometry. This process is based on the “etching in microchannel” technology we developed earlier (doi:10.1088/1742-6596/681/1/012035). Our method ensures a precise control of the flow rate and flow direction in the bridge microchannel. The advantage of our approach is the ability to work without any control valves and other active electronic systems, which are usually used for bridge balancing. The geometrical configuration of microchannels was selected based on the analytical estimations. A detailed 3D numerical model was based on Navier-Stokes equations for a laminar fluid flow at low Reynolds numbers. We investigated the behavior of the Wheatstone bridge under different process conditions; found a relation between the channel resistance and flow rate through the bridge; and calculated the pressure drop across the system under different total flow rates and viscosities. Finally, we describe a high-precision microfluidic pressure sensor that employs the Wheatstone bridge and discuss other applications in complex precision microfluidic systems.

When and where does preferential flow matter - from observation to large scale modelling

NASA Astrophysics Data System (ADS)

Weiler, Markus; Leistert, Hannes; Steinbrich, Andreas

2017-04-01

Preferential flow can be of relevance in a wide range of soils and the interaction of different processes and factors are still difficult to assess. As most studies (including our own studies) focusing on the effect of preferential flow are based on relatively high precipitation rates, there is always the question how relevant preferential flow is under natural conditions, considering the site specific precipitation characteristics, the effect of the drying and wetting cycle on the initial soil water condition and shrinkage cracks, the site specific soil properties, soil structure and rock fragments, and the effect of plant roots and soil fauna (e.g. earthworm channels). In order to assess this question, we developed the distributed, process-based model RoGeR (Runoff Generation Research) to include a large number relevant features and processes of preferential flow in soils. The model was developed from a large number of process based research and experiments and includes preferential flow in roots, earthworm channels, along rock fragments and shrinkage cracks. We parameterized the uncalibrated model at a high spatial resolution of 5x5m for the whole state of Baden-Württemberg in Germany using LiDAR data, degree of sealing, landuse, soil properties and geology. As the model is an event based model, we derived typical event based precipitation characteristics based on rainfall duration, mean intensity and amount. Using the site-specific variability of initial soil moisture derived from a water balance model based on the same dataset, we simulated the infiltration and recharge amounts of all event classes derived from the event precipitation characteristics and initial soil moisture conditions. The analysis of the simulation results allowed us to extracts the relevance of preferential flow for infiltration and recharge considering all factors above. We could clearly see a strong effect of the soil properties and land-use, but also, particular for clay rich soils a strong effect of the initial conditions due to the development of soil cracks. Not too surprisingly, the relevance of preferential flow was much lower when considering the whole range of precipitation events as only considering events with a high rainfall intensity. Also, the influence on infiltration and recharge were different. Despite the model can still be improved in particular considering more realistic information about the spatial and temporal variability of preferential flow by soil fauna and plants, the model already shows under what situation we need to be very careful when predicting infiltration and recharge with models considering only longer time steps (daily) or only matrix flow.

Simulation of interior ballistics flows in a shock tube

NASA Astrophysics Data System (ADS)

Seiler, F.

1983-07-01

The flow in front of and behind a projectile was investigated in a interior ballistics shock tube simulator. Flow patterns and heat flow were examined for flows with and without gas leakage. The boundary layers behind the piston can clearly be shown by differential interferograms. The dependence of the heat flow into the measuring tube wall on the base form is smaller than the signal perturbations. Flow patterns show no appreciable effect of gas leakage on the flow behind the piston; strong flow effects arise in front of the piston. The same effects are shown by heat flow measurements. In case of gas leakage heat flows into the tube wall before the piston reaches the wall. In the slit between piston and wall a maximum heat flow is found. High temperature gradients, due to the fact that hot gases come closer to the tube wall than in the boundary layer flow behind the piston, lead to high thermal loading of the wall materials which can cause cracks.

Large eddy simulations and direct numerical simulations of high speed turbulent reacting flows

NASA Technical Reports Server (NTRS)

Givi, P.; Madnia, C. K.; Steinberger, C. J.; Frankel, S. H.

1992-01-01

The basic objective of this research is to extend the capabilities of Large Eddy Simulations (LES) and Direct Numerical Simulations (DNS) for the computational analyses of high speed reacting flows. In the efforts related to LES, we were primarily involved with assessing the performance of the various modern methods based on the Probability Density Function (PDF) methods for providing closures for treating the subgrid fluctuation correlations of scalar quantities in reacting turbulent flows. In the work on DNS, we concentrated on understanding some of the relevant physics of compressible reacting flows by means of statistical analysis of the data generated by DNS of such flows. In the research conducted in the second year of this program, our efforts focused on the modeling of homogeneous compressible turbulent flows by PDF methods, and on DNS of non-equilibrium reacting high speed mixing layers. Some preliminary work is also in progress on PDF modeling of shear flows, and also on LES of such flows.

Early harvesting of the vascularized pedicled nasoseptal flap during endoscopic skull base surgery.

PubMed

Eloy, Jean Anderson; Patel, Amit A; Shukla, Pratik A; Choudhry, Osamah J; Liu, James K

2013-01-01

The vascularized pedicled nasoseptal flap (PNSF) represents a successful option for reconstruction of large skull base defects after expanded endoscopic endonasal approaches (EEA). This vascularized flap can be harvested early or late in the operation depending on the anticipation of high-flow CSF leaks. Each harvesting technique (early vs. late) is associated with different advantages and disadvantages. In this study, we evaluate our experience with early harvesting of the PNSF for repair of large skull base defects after EEA. A retrospective review was performed at a tertiary care medical center on patients who underwent early PNSF harvesting during reconstruction of intraoperative high-flow CSF leaks after EEA between December 2008 and March 2012. Demographic data, repair materials, surgical approach, and incidence of PNSF usage were collected. Eighty-seven patients meeting the inclusion criteria were identified. In 86 procedures (98.9%), the PNSF harvested at the beginning of the operation was used. In 1 case (1.1%), the PNSF was not used because a high-flow intraoperative CSF leak was not encountered. This patient had recurrence of intradural disease 8months later, and the previously elevated PNSF was subsequent used after tumor resection. Based on our data, a high-flow CSF leak and need for a PNSF can be accurately anticipated in patients undergoing EEA for skull base lesions. Because of the advantages of early harvesting of the PNSF and the high preoperative predictive value of CSF leak anticipations, this technique represents a feasible harvesting practice for EEA surgeries. Copyright © 2013 Elsevier Inc. All rights reserved.

High-speed technique based on a parallel projection correlation procedure for digital image correlation

NASA Astrophysics Data System (ADS)

Zaripov, D. I.; Renfu, Li

2018-05-01

The implementation of high-efficiency digital image correlation methods based on a zero-normalized cross-correlation (ZNCC) procedure for high-speed, time-resolved measurements using a high-resolution digital camera is associated with big data processing and is often time consuming. In order to speed-up ZNCC computation, a high-speed technique based on a parallel projection correlation procedure is proposed. The proposed technique involves the use of interrogation window projections instead of its two-dimensional field of luminous intensity. This simplification allows acceleration of ZNCC computation up to 28.8 times compared to ZNCC calculated directly, depending on the size of interrogation window and region of interest. The results of three synthetic test cases, such as a one-dimensional uniform flow, a linear shear flow and a turbulent boundary-layer flow, are discussed in terms of accuracy. In the latter case, the proposed technique is implemented together with an iterative window-deformation technique. On the basis of the results of the present work, the proposed technique is recommended to be used for initial velocity field calculation, with further correction using more accurate techniques.

Identifying Hydrogeological Controls of Catchment Low-Flow Dynamics Using Physically Based Modelling

NASA Astrophysics Data System (ADS)

Cochand, F.; Carlier, C.; Staudinger, M.; Seibert, J.; Hunkeler, D.; Brunner, P.

2017-12-01

Identifying key catchment characteristics and processes which control the hydrological response under low-flow conditions is important to assess the catchments' vulnerability to dry periods. In the context of a Swiss Federal Office for the Environment (FOEN) project, the low-flow behaviours of two mountainous catchments were investigated. These neighboring catchments are characterized by the same meteorological conditions, but feature completely different river flow dynamics. The Roethenbach is characterized by high peak flows and low mean flows. Conversely, the Langete is characterized by relatively low peak flows and high mean flow rates. To understand the fundamentally different behaviour of the two catchments, a physically-based surface-subsurface flow HydroGeoSphere (HGS) model for each catchment was developed. The main advantage of a physically-based model is its ability to realistically reproduce processes which play a key role during low-flow periods such as surface-subsurface interactions or evapotranspiration. Both models were calibrated to reproduce measured groundwater heads and the surface flow dynamics. Subsequently, the calibrated models were used to explore the fundamental physics that control hydrological processes during low-flow periods. To achieve this, a comparative sensitivity analysis of model parameters of both catchments was carried out. Results show that the hydraulic conductivity of the bedrock (and weathered bedrock) controls the catchment water dynamics in both models. Conversely, the properties of other geological formations such as alluvial aquifer or soil layer hydraulic conductivity or porosity play a less important role. These results change significantly our perception of the streamflow catchment dynamics and more specifically the way to assess catchment vulnerability to dry period. This study suggests that by analysing catchment scale bedrock properties, the catchment dynamics and the vulnerability to dry period may be assessed.

Vortex dynamics studies in supersonic flow

NASA Astrophysics Data System (ADS)

Vergine, Fabrizio

This dissertation covers the study of selected vortex interaction scenarios both in cold and high enthalpy reacting flows. Specifically, the experimental results and the analysis of the flowfields resulting from two selected supersonic vortex interaction modes in a Mach 2.5 cold flow are presented. Additionally, the experiment design, based on vortex dynamics concepts, and the reacting plume survey of two pylon injectors in a Mach 2.4 high enthalpy flow are shown. All the cold flow experiments were conducted in the supersonic wind tunnel of the Aerodynamics Research Center at the University of Texas at Arlington. A strut injector equipped with specified ramp configurations was designed and used to produce the flowfields of interest. The reacting flow experiments were conducted in the the Expansion Tube Facility located in the High Temperature Gasdynamics Laboratory of Stanford University. A detailed description of the supersonic wind tunnel, the instrumentation, the strut injector and the supersonic wake flow downstream is shown as part of the characterization of the facility. As Stereoscopic Particle Image Velocimetry was the principal flow measurement technique used in this work to probe the streamwise vortices shed from ramps mounted on the strut, this dissertation provides a deep overview of the challenges and the application of the aforementioned technique to the survey of vortical flows. Moreover, the dissertation provides the comprehensive analysis of the mean and fluctuating velocity flowfields associated with two distinct vortex dynamics scenarios, as chosen by means of the outcomes of the simulations of a reduced order model developed in the research group. Specifically, the same streamwise vortices (strength, size and Reynolds number) were used experimentally to investigate both a case in which the resulting dynamics evolve in a vortex merging scenario and a case where the merging process is voluntarily avoided in order to focus the analysis on the fundamental differences associated with the amalgamation processes alone. The results from the mean flow highlight major differences between the two cases and will justify the use of the inviscid reduced order model used to predict the main flow physics. The analysis of the turbulence quantities based on concepts borrowed from incompressible turbulence theory explains interesting features of the fluctuating flowfields, suggesting that turbulence associated with the inspected flow conditions is essentially incompressible. Once the interactions among the vortical structures in cold flow were assessed, these vortex dynamics concepts were probed in a reacting environment. The dissertation describes the design phase of two pylon injectors based on the prediction capabilities of the aforementioned model. Then, the results of a set of combustion experiments conducted utilizing hydrogen fuel injected into Mach 2.4, high-enthalpy (2.8˜MJ/kg) air flow are discussed. The results show that, for the heat release levels considered in this study, the morphology of the plume and its evolution is very similar to the results produced by the code, enabling an interpretation of the phenomena based on vortex dynamics considerations. The persistence of the streamwise vortical structures created by the selected ramp configurations is shown together with the effectiveness of the coherent structures in successfully anchoring the flame very close to the injection point. The work shows the possibility of a new approach in the design of injection strategies (i.e., not limited to injection devices) suitable for adoption in scramjet combustors based on the ability to predict, with basic vortex dynamics concepts and a highly reduced computational cost, the main features of flows of technological interest.

Dynamics of current-use pesticides in the agricultural model basin

NASA Astrophysics Data System (ADS)

Perez, Debora; Okada, Elena; Menone, Mirta; Aparicio, Virginia; Costa, Jose Luis

2017-04-01

The southeast of the Pampas plains is a zone with intensive agricultural activities; this zone is highly irrigated by wetlands, rivers and many streams. The stream flow dynamics are strongly related to the regional humidity, mainly given by runoff water and phreatic surface level, and can change dramatically during storm events. In this sense, it is important to study the fluctuations in the loads and mass of current-use pesticide (CUPs) to examine the influence of hydrologic and seasonal variability on the response of pesticide levels. The objective of this work was to determine the maximum loads reached of ∑CUPs and mass of CUPs associated with the flow dynamic in surface waters of "El Crespo" stream. "El Crespo" stream is only influenced by farming activities, with intensive crop systems upstream (US) and extensive livestock production downstream (DS). It is an optimal site for pesticide monitoring studies since there are no urban or industrial inputs into the system. Water samples were collected monthly from October 2014 to October 2015 in the UP and DN sites using 1 L polypropylene bottles and stored at -20°C until analysis. The samples were analyzed using liquid chromatography coupled to a tandem mass spectrometer (UPLC-MS/MS). The stream flow was measured during the sampling times in both sites, covering low base-flow and high base-flow periods. The most frequently detected residues (>40%) were glyphosate and its metabolite AMPA, atrazine, acetochlor, metolachlor, 2,4-D, metsulfuron methyl, fluorocloridone, imidacloprid, tebuconazole and epoxiconazole. The mean concentrations of ∑CUPs during the sampling period were 1.62µg/L and 1.66µg/L in UP site and DN site, respectively. The highest levels of ∑CUPs were 4.03 µg/L in UP site during spring 2014 and 2.53 µg/L in DN site during winter 2014. The mass of ∑CUPs showed a direct relation between low base flow and high base flow periods. During high base flow during spring 2014, the stream discharge showed peak of 6.16 mt3/s and 6.77 mt3/s, in UP and DN site, respectively; where the total loads of ∑CUPs were 3.7 µg/L and 2.88 µg/L and the associated mass were 22.74 and 19.54 µg/s, in UP and DN site, respectively. During low base flow the discharge were lower than 1 mt3/s and the total loads of ∑CUPs were variable between 1-3 µg/L, but the mass never were higher than 3 µg/s. The intensive rain during the spring 2014, were the mainly factor that influence the stream flow and pesticide dynamics in the model basin

Measurement and control systems for an imaging electromagnetic flow metre.

PubMed

Zhao, Y Y; Lucas, G; Leeungculsatien, T

2014-03-01

Electromagnetic flow metres based on the principles of Faraday's laws of induction have been used successfully in many industries. The conventional electromagnetic flow metre can measure the mean liquid velocity in axisymmetric single phase flows. However, in order to achieve velocity profile measurements in single phase flows with non-uniform velocity profiles, a novel imaging electromagnetic flow metre (IEF) has been developed which is described in this paper. The novel electromagnetic flow metre which is based on the 'weight value' theory to reconstruct velocity profiles is interfaced with a 'Microrobotics VM1' microcontroller as a stand-alone unit. The work undertaken in the paper demonstrates that an imaging electromagnetic flow metre for liquid velocity profile measurement is an instrument that is highly suited for control via a microcontroller. © 2013 ISA Published by ISA All rights reserved.

Heat Transfer Enhancement in High Performance Heat Sink Channels by Autonomous, Aero-Elastic Reed Fluttering

NASA Astrophysics Data System (ADS)

Jha, Sourabh; Crittenden, Thomas; Glezer, Ari

2016-11-01

Heat transport within high aspect ratio, rectangular mm-scale channels that model segments of a high-performance, air-cooled heat sink is enhanced by the formation of unsteady small-scale vortical motions induced by autonomous, aeroelastic fluttering of cantilevered planar thin-film reeds. The flow mechanisms and scaling of the interactions between the reed and the channel flow are explored to overcome the limits of forced convection heat transport from air-side heat exchangers. High-resolution PIV measurements in a testbed model show that undulations of the reed's surface lead to formation and advection of vorticity concentrations, and to alternate shedding of spanwise CW and CCW vortices. These vortices scale with the reed motion amplitude, and ultimately result in motions of decreasing scales and enhanced dissipation that are reminiscent of a turbulent flow. The vorticity shedding lead to strong enhancement in heat transfer that increases with the Reynolds number of the base flow (e.g., the channel's thermal coefficient of performance is enhanced by 2.4-fold and 9-fold for base flow Re = 4,000 and 17,400, respectively, with corresponding decreases of 50 and 77% in the required channel flow rates). This is demonstrated in heat sinks for improving the thermal performance of low-Re thermoelectric power plant air-cooled condensers, where the global air-side pressure losses can be significantly reduced by lowering the required air volume flow rate at a given heat flux and surface temperature. AFOSR and NSF-EPRI.

Natural streamflow simulation for two largest river basins in Poland: a baseline for identification of flow alterations

NASA Astrophysics Data System (ADS)

Piniewski, Mikołaj

2016-05-01

The objective of this study was to apply a previously developed large-scale and high-resolution SWAT model of the Vistula and the Odra basins, calibrated with the focus of natural flow simulation, in order to assess the impact of three different dam reservoirs on streamflow using the Indicators of Hydrologic Alteration (IHA). A tailored spatial calibration approach was designed, in which calibration was focused on a large set of relatively small non-nested sub-catchments with semi-natural flow regime. These were classified into calibration clusters based on the flow statistics similarity. After performing calibration and validation that gave overall positive results, the calibrated parameter values were transferred to the remaining part of the basins using an approach based on hydrological similarity of donor and target catchments. The calibrated model was applied in three case studies with the purpose of assessing the effect of dam reservoirs (Włocławek, Siemianówka and Czorsztyn Reservoirs) on streamflow alteration. Both the assessment based on gauged streamflow (Before-After design) and the one based on simulated natural streamflow showed large alterations in selected flow statistics related to magnitude, duration, high and low flow pulses and rate of change. Some benefits of using a large-scale and high-resolution hydrological model for the assessment of streamflow alteration include: (1) providing an alternative or complementary approach to the classical Before-After designs, (2) isolating the climate variability effect from the dam (or any other source of alteration) effect, (3) providing a practical tool that can be applied at a range of spatial scales over large area such as a country, in a uniform way. Thus, presented approach can be applied for designing more natural flow regimes, which is crucial for river and floodplain ecosystem restoration in the context of the European Union's policy on environmental flows.

High-speed engine/component performance assessment using exergy and thrust-based methods

NASA Technical Reports Server (NTRS)

Riggins, D. W.

1996-01-01

This investigation summarizes a comparative study of two high-speed engine performance assessment techniques based on energy (available work) and thrust-potential (thrust availability). Simple flow-fields utilizing Rayleigh heat addition and one-dimensional flow with friction are used to demonstrate the fundamental inability of conventional energy techniques to predict engine component performance, aid in component design, or accurately assess flow losses. The use of the thrust-based method on these same examples demonstrates its ability to yield useful information in all these categories. Energy and thrust are related and discussed from the stand-point of their fundamental thermodynamic and fluid dynamic definitions in order to explain the differences in information obtained using the two methods. The conventional definition of energy is shown to include work which is inherently unavailable to an aerospace Brayton engine. An engine-based energy is then developed which accurately accounts for this inherently unavailable work; performance parameters based on this quantity are then shown to yield design and loss information equivalent to the thrust-based method.

Dynamics and Control of Newtonian and Viscoelastic Fluids

NASA Astrophysics Data System (ADS)

Lieu, Binh K.

Transition to turbulence represents one of the most intriguing natural phenomena. Flows that are smooth and ordered may become complex and disordered as the flow strength increases. This process is known as transition to turbulence. In this dissertation, we develop theoretical and computational tools for analysis and control of transition and turbulence in shear flows of Newtonian, such as air and water, and complex viscoelastic fluids, such as polymers and molten plastics. Part I of the dissertation is devoted to the design and verification of sensor-free and feedback-based strategies for controlling the onset of turbulence in channel flows of Newtonian fluids. We use high fidelity simulations of the nonlinear flow dynamics to demonstrate the effectiveness of our model-based approach to flow control design. In Part II, we utilize systems theoretic tools to study transition and turbulence in channel flows of viscoelastic fluids. For flows with strong elastic forces, we demonstrate that flow fluctuations can experience significant amplification even in the absence of inertia. We use our theoretical developments to uncover the underlying physical mechanism that leads to this high amplification. For turbulent flows with polymer additives, we develop a model-based method for analyzing the influence of polymers on drag reduction. We demonstrate that our approach predicts drag reducing trends observed in full-scale numerical simulations. In Part III, we develop mathematical framework and computational tools for calculating frequency responses of spatially distributed systems. Using state-of-the-art automatic spectral collocation techniques and new integral formulation, we show that our approach yields more reliable and accurate solutions than currently available methods.

Traffic Flow Density Distribution Based on FEM

NASA Astrophysics Data System (ADS)

Ma, Jing; Cui, Jianming

In analysis of normal traffic flow, it usually uses the static or dynamic model to numerical analyze based on fluid mechanics. However, in such handling process, the problem of massive modeling and data handling exist, and the accuracy is not high. Finite Element Method (FEM) is a production which is developed from the combination of a modern mathematics, mathematics and computer technology, and it has been widely applied in various domain such as engineering. Based on existing theory of traffic flow, ITS and the development of FEM, a simulation theory of the FEM that solves the problems existing in traffic flow is put forward. Based on this theory, using the existing Finite Element Analysis (FEA) software, the traffic flow is simulated analyzed with fluid mechanics and the dynamics. Massive data processing problem of manually modeling and numerical analysis is solved, and the authenticity of simulation is enhanced.

Regional variation of flow duration curves in the eastern United States: Process-based analyses of the interaction between climate and landscape properties

NASA Astrophysics Data System (ADS)

Chouaib, Wafa; Caldwell, Peter V.; Alila, Younes

2018-04-01

This paper advances the physical understanding of the flow duration curve (FDC) regional variation. It provides a process-based analysis of the interaction between climate and landscape properties to explain disparities in FDC shapes. We used (i) long term measured flow and precipitation data over 73 catchments from the eastern US. (ii) We calibrated the Sacramento model (SAC-SMA) to simulate soil moisture and flow components FDCs. The catchments classification based on storm characteristics pointed to the effect of catchments landscape properties on the precipitation variability and consequently on the FDC shapes. The landscape properties effect was pronounce such that low value of the slope of FDC (SFDC)-hinting at limited flow variability-were present in regions of high precipitation variability. Whereas, in regions with low precipitation variability the SFDCs were of larger values. The topographic index distribution, at the catchment scale, indicated that saturation excess overland flow mitigated the flow variability under conditions of low elevations with large soil moisture storage capacity and high infiltration rates. The SFDCs increased due to the predominant subsurface stormflow in catchments at high elevations with limited soil moisture storage capacity and low infiltration rates. Our analyses also highlighted the major role of soil infiltration rates on the FDC despite the impact of the predominant runoff generation mechanism and catchment elevation. In conditions of slow infiltration rates in soils of large moisture storage capacity (at low elevations) and predominant saturation excess, the SFDCs were of larger values. On the other hand, the SFDCs decreased in catchments of prevalent subsurface stormflow and poorly drained soils of small soil moisture storage capacity. The analysis of the flow components FDCs demonstrated that the interflow contribution to the response was the higher in catchments with large value of slope of the FDC. The surface flow FDC was the most affected by the precipitation as it tracked the precipitation duration curve (PDC). In catchments with low SFDCs, this became less applicable as surface flow FDC diverged from PDC at the upper tail (> 40% of the flow percentile). The interflow and baseflow FDCs illustrated most the filtering effect on the precipitation. The process understanding we achieved in this study is key for flow simulation and assessment in addition to future works focusing on process-based FDC predictions.

A new strategy to produce low-density polyethylene (LDPE)-based composites simultaneously with high flame retardancy and high mechanical properties

NASA Astrophysics Data System (ADS)

Shen, Liguo; Li, Jianxi; Li, Renjie; Lin, Hongjun; Chen, Jianrong; Liao, Bao-Qiang

2018-04-01

In this study, a new strategy which blends low-density polyethylene (LDPE), magnesium hydroxide (MH) and lauryl acrylate by electron-beam radiation for production of LDPE-based composites with high performance was proposed. It was found that, MH played main roles in flame retardancy but reduced processing flow and mechanical properties of the composites. Meanwhile, melt flow rate (MFR) increased while viscosity of the composites decreased with lauryl acrylate content increased, facilitating LDPE composites processing. Electron beam radiation could prompt crosslinking of lauryl acrylate, which significantly enhanced the mechanical properties of LDPE composites. Meanwhile, lauryl acrylate addition only slightly decreased the flame retardancy, suggesting that LDPE composites could remain high flame retardancy even when lauryl acrylate content was high. The study highly demonstrated the feasibility to produce LDPE-based composites simultaneously with high flame retardancy and high mechanical properties by the blending strategy provided in this study.

Flow cytometric HyPer-based assay for hydrogen peroxide.

PubMed

Lyublinskaya, O G; Antonov, S A; Gorokhovtsev, S G; Pugovkina, N A; Kornienko, Ju S; Ivanova, Ju S; Shatrova, A N; Aksenov, N D; Zenin, V V; Nikolsky, N N

2018-05-30

HyPer is a genetically encoded fluorogenic sensor for hydrogen peroxide which is generally used for the ratiometric imaging of H 2 O 2 fluxes in living cells. Here, we demonstrate the advantages of HyPer-based ratiometric flow cytometry assay for H 2 O 2 , by using K562 and human mesenchymal stem cell lines expressing HyPer. We show that flow cytometry analysis is suitable to detect HyPer response to submicromolar concentrations of extracellularly added H 2 O 2 that is much lower than concentrations addressed previously in the other HyPer-based assays (such as cell imaging or fluorimetry). Suggested technique is also much more sensitive to hydrogen peroxide than the widespread flow cytometry assay exploiting H 2 O 2 -reactive dye H 2 DCFDA and, contrary to the H 2 DCFDA-based assay, can be employed for the kinetic studies of H 2 O 2 utilization by cells, including measurements of the rate constants of H 2 O 2 removal. In addition, flow cytometry multi-parameter ratiometric measurements enable rapid and high-throughput detection of endogenously generated H 2 O 2 in different subpopulations of HyPer-expressing cells. To sum up, HyPer can be used in multi-parameter flow cytometry studies as a highly sensitive indicator of intracellular H 2 O 2 . Copyright © 2018. Published by Elsevier Inc.

On the peculiarities of LDA method in two-phase flows with high concentrations of particles

NASA Astrophysics Data System (ADS)

Poplavski, S. V.; Boiko, V. M.; Nesterov, A. U.

2016-10-01

Popular applications of laser Doppler anemometry (LDA) in gas dynamics are reviewed. It is shown that the most popular method cannot be used in supersonic flows and two-phase flows with high concentrations of particles. A new approach to implementation of the known LDA method based on direct spectral analysis, which offers better prospects for such problems, is presented. It is demonstrated that the method is suitable for gas-liquid jets. Owing to the progress in laser engineering, digital recording of spectra, and computer processing of data, the method is implemented at a higher technical level and provides new prospects of diagnostics of high-velocity dense two-phase flows.

Simulation of thermal transpiration flow using a high-order moment method

NASA Astrophysics Data System (ADS)

Sheng, Qiang; Tang, Gui-Hua; Gu, Xiao-Jun; Emerson, David R.; Zhang, Yong-Hao

2014-04-01

Nonequilibrium thermal transpiration flow is numerically analyzed by an extended thermodynamic approach, a high-order moment method. The captured velocity profiles of temperature-driven flow in a parallel microchannel and in a micro-chamber are compared with available kinetic data or direct simulation Monte Carlo (DSMC) results. The advantages of the high-order moment method are shown as a combination of more accuracy than the Navier-Stokes-Fourier (NSF) equations and less computation cost than the DSMC method. In addition, the high-order moment method is also employed to simulate the thermal transpiration flow in complex geometries in two types of Knudsen pumps. One is based on micro-mechanized channels, where the effect of different wall temperature distributions on thermal transpiration flow is studied. The other relies on porous structures, where the variation of flow rate with a changing porosity or pore surface area ratio is investigated. These simulations can help to optimize the design of a real Knudsen pump.

Determining the frequency, depth and velocity of preferential flow by high frequency soil moisture monitoring

NASA Astrophysics Data System (ADS)

Hardie, Marcus; Lisson, Shaun; Doyle, Richard; Cotching, William

2013-01-01

Preferential flow in agricultural soils has been demonstrated to result in agrochemical mobilisation to shallow ground water. Land managers and environmental regulators need simple cost effective techniques for identifying soil - land use combinations in which preferential flow occurs. Existing techniques for identifying preferential flow have a range of limitations including; often being destructive, non in situ, small sampling volumes, or are subject to artificial boundary conditions. This study demonstrated that high frequency soil moisture monitoring using a multi-sensory capacitance probe mounted within a vertically rammed access tube, was able to determine the occurrence, depth, and wetting front velocity of preferential flow events following rainfall. Occurrence of preferential flow was not related to either rainfall intensity or rainfall amount, rather preferential flow occurred when antecedent soil moisture content was below 226 mm soil moisture storage (0-70 cm). Results indicate that high temporal frequency soil moisture monitoring may be used to identify soil type - land use combinations in which the presence of preferential flow increases the risk of shallow groundwater contamination by rapid transport of agrochemicals through the soil profile. However use of high frequency based soil moisture monitoring to determine agrochemical mobilisation risk may be limited by, inability to determine the volume of preferential flow, difficulty observing macropore flow at high antecedent soil moisture content, and creation of artificial voids during installation of access tubes in stony soils.

High-performance, low-voltage electroosmotic pumps with molecularly thin silicon nanomembranes

PubMed Central

Snyder, Jessica L.; Getpreecharsawas, Jirachai; Fang, David Z.; Gaborski, Thomas R.; Striemer, Christopher C.; Fauchet, Philippe M.; Borkholder, David A.; McGrath, James L.

2013-01-01

We have developed electroosmotic pumps (EOPs) fabricated from 15-nm-thick porous nanocrystalline silicon (pnc-Si) membranes. Ultrathin pnc-Si membranes enable high electroosmotic flow per unit voltage. We demonstrate that electroosmosis theory compares well with the observed pnc-Si flow rates. We attribute the high flow rates to high electrical fields present across the 15-nm span of the membrane. Surface modifications, such as plasma oxidation or silanization, can influence the electroosmotic flow rates through pnc-Si membranes by alteration of the zeta potential of the material. A prototype EOP that uses pnc-Si membranes and Ag/AgCl electrodes was shown to pump microliter per minute-range flow through a 0.5-mm-diameter capillary tubing with as low as 250 mV of applied voltage. This silicon-based platform enables straightforward integration of low-voltage, on-chip EOPs into portable microfluidic devices with low back pressures. PMID:24167263

Some predictions of the attached eddy model for a high Reynolds number boundary layer.

PubMed

Nickels, T B; Marusic, I; Hafez, S; Hutchins, N; Chong, M S

2007-03-15

Many flows of practical interest occur at high Reynolds number, at which the flow in most of the boundary layer is turbulent, showing apparently random fluctuations in velocity across a wide range of scales. The range of scales over which these fluctuations occur increases with the Reynolds number and hence high Reynolds number flows are difficult to compute or predict. In this paper, we discuss the structure of these flows and describe a physical model, based on the attached eddy hypothesis, which makes predictions for the statistical properties of these flows and their variation with Reynolds number. The predictions are shown to compare well with the results from recent experiments in a new purpose-built high Reynolds number facility. The model is also shown to provide a clear physical explanation for the trends in the data. The limits of applicability of the model are also discussed.

Deployable Emergency Shutoff Device Blocks High-Velocity Fluid Flows

NASA Technical Reports Server (NTRS)

Nabors, Sammy A.

2015-01-01

NASA's Marshall Space Flight Center has developed a device and method for blocking the flow of fluid from an open pipe. Motivated by the sea-bed oil-drilling catastrophe in the Gulf of Mexico in 2010, NASA innovators designed the device to plug, control, and meter the flow of gases and liquids. Anchored with friction fittings, spikes, or explosively activated fasteners, the device is well-suited for harsh environments and high fluid velocities and pressures. With the addition of instrumentation, it can also be used as a variable area flow metering valve that can be set based upon flow conditions. With robotic additions, this patent-pending innovation can be configured to crawl into a pipe then anchor and activate itself to block or control fluid flow.

Large eddy simulations and direct numerical simulations of high speed turbulent reacting flows

NASA Technical Reports Server (NTRS)

Givi, Peyman; Madnia, C. K.; Steinberger, C. J.; Tsai, A.

1991-01-01

This research is involved with the implementations of advanced computational schemes based on large eddy simulations (LES) and direct numerical simulations (DNS) to study the phenomenon of mixing and its coupling with chemical reactions in compressible turbulent flows. In the efforts related to LES, a research program was initiated to extend the present capabilities of this method for the treatment of chemically reacting flows, whereas in the DNS efforts, focus was on detailed investigations of the effects of compressibility, heat release, and nonequilibrium kinetics modeling in high speed reacting flows. The efforts to date were primarily focussed on simulations of simple flows, namely, homogeneous compressible flows and temporally developing hign speed mixing layers. A summary of the accomplishments is provided.

A hydrometric and geochemical approach to test the transmissivity feedback hypothesis during snowmelt

USGS Publications Warehouse

Kendall, K.A.; Shanley, J.B.; McDonnell, Jeffery J.

1999-01-01

To test the transmissivity feedback hypothesis of runoff generation, surface and subsurface waters were monitored and sampled during the 1996 snowmelt at various topographic positions in a 41 ha forested headwater catchment at Sleepers River, Vermont. Two conditions that promote transmissivity feedback existed in the catchment during the melt period. First, saturated hydraulic conductivity increased toward land surface, from a geometric mean of 3.6 mm h-1 in glacial till to 25.6 mm h-1 in deep soil to 54.0 mm h-1 in shallow soil. Second, groundwater levels rose to within 0.3 m of land surface at all riparian sites and most hillslope sites at peak melt. The importance of transmissivity feedback to streamflow generation was tested at the catchment scale by examination of physical and chemical patterns of groundwater in near-stream (discharge) and hillslope (recharge/lateral flow) zones, and within a geomorphic hollow (convergent flow). The presence of transmissivity feedback was supported by the abrupt increase in streamflow as the water table rose into the surficial, transmissive zone; a flattening of the groundwater level vs. streamflow curve occurred at most sites. This relation had a clockwise hysteresis (higher groundwater level for given discharge on rising limb than at same discharge on falling limb) at riparian sites, suggesting that the riparian zone was the dominant source area during the rising limb of the melt hydrograph. Hysteresis was counterclockwise at hillslope sites, suggesting that hillslope drainage controlled the snowmelt recession. End member mixing analysis using Ca, Mg, Na, dissolved organic carbon (DOC), and Si showed that stream chemistry could be explained as a two-component mixture of groundwater high in base cations and an O-horizon/overland flow water high in DOC. The dominance of shallow flow paths during events was indicated by the high positive correlation of DOC with streamflow (r2 = 0.82). Despite the occurrence of transmissivity feedback, hillslope till and soil water were ruled out as end members primarily because their distinctive high-Si composition had little or no effect on streamwater composition. Till water from the geomorphic hollow had a chemistry very close to streamwater base flow, and may represent the base flow end member better than the more concentrated riparian groundwater. During snowmelt, streamwater composition shifted as this base flow was diluted - not by shallow groundwater from the hillslope, but rather by a more surficial O-horizon/overland flow water.Surface and subsurface waters were analyzed to test the transmissivity feedback of runoff generation during the 1996 snowmelt in a catchment at Sleepers River, Vermont. The importance of transmissivity feedback to stream flow generation was tested by examination of physical and chemical patterns of groundwater in near-stream and hillslope zones within a geomorphic hollow. End member mixing analysis of Ca, Mg, Na, dissolved organic carbon (DOC), and Si showed that stream chemistry could be explained as a two-component mixture of groundwater high in base cations and an O-horizon/overland flow water high in DOC. The dominance of shallow water paths during the events was indicated by the high positive correlation of DOC with streamflow (r2 = 0.82).

Towards an entropy-based detached-eddy simulation

NASA Astrophysics Data System (ADS)

Zhao, Rui; Yan, Chao; Li, XinLiang; Kong, WeiXuan

2013-10-01

A concept of entropy increment ratio ( s¯) is introduced for compressible turbulence simulation through a series of direct numerical simulations (DNS). s¯ represents the dissipation rate per unit mechanical energy with the benefit of independence of freestream Mach numbers. Based on this feature, we construct the shielding function f s to describe the boundary layer region and propose an entropy-based detached-eddy simulation method (SDES). This approach follows the spirit of delayed detached-eddy simulation (DDES) proposed by Spalart et al. in 2005, but it exhibits much better behavior after their performances are compared in the following flows, namely, pure attached flow with thick boundary layer (a supersonic flat-plate flow with high Reynolds number), fully separated flow (the supersonic base flow), and separated-reattached flow (the supersonic cavity-ramp flow). The Reynolds-averaged Navier-Stokes (RANS) resolved region is reliably preserved and the modeled stress depletion (MSD) phenomenon which is inherent in DES and DDES is partly alleviated. Moreover, this new hybrid strategy is simple and general, making it applicable to other models related to the boundary layer predictions.

On the development of OpenFOAM solvers based on explicit and implicit high-order Runge-Kutta schemes for incompressible flows with heat transfer

NASA Astrophysics Data System (ADS)

D'Alessandro, Valerio; Binci, Lorenzo; Montelpare, Sergio; Ricci, Renato

2018-01-01

Open-source CFD codes provide suitable environments for implementing and testing low-dissipative algorithms typically used to simulate turbulence. In this research work we developed CFD solvers for incompressible flows based on high-order explicit and diagonally implicit Runge-Kutta (RK) schemes for time integration. In particular, an iterated PISO-like procedure based on Rhie-Chow correction was used to handle pressure-velocity coupling within each implicit RK stage. For the explicit approach, a projected scheme was used to avoid the "checker-board" effect. The above-mentioned approaches were also extended to flow problems involving heat transfer. It is worth noting that the numerical technology available in the OpenFOAM library was used for space discretization. In this work, we additionally explore the reliability and effectiveness of the proposed implementations by computing several unsteady flow benchmarks; we also show that the numerical diffusion due to the time integration approach is completely canceled using the solution techniques proposed here.

Battery operated preconcentration-assisted lateral flow assay.

PubMed

Kim, Cheonjung; Yoo, Yong Kyoung; Han, Sung Il; Lee, Junwoo; Lee, Dohwan; Lee, Kyungjae; Hwang, Kyo Seon; Lee, Kyu Hyoung; Chung, Seok; Lee, Jeong Hoon

2017-07-11

Paper-based analytical devices (e.g. lateral flow assays) are highly advantageous as portable diagnostic systems owing to their low costs and ease of use. Because of their low sensitivity and detection limits for biomolecules, these devices have several limitations in applications for real-field diagnosis. Here, we demonstrate a paper-based preconcentration enhanced lateral flow assay using a commercial β-hCG-based test. Utilizing a simple 9 V battery operation with a low power consumption of approximately 81 μW, we acquire a 25-fold preconcentration factor, demonstrating a clear sensitivity enhancement in the colorimetric lateral flow assay; consequently, clear colors are observed in a rapid kit test line, which cannot be monitored without preconcentration. This device can also facilitate a semi-quantitative platform using the saturation value and/or color intensity in both paper-based colorimetric assays and smartphone-based diagnostics.

A MEMS-based Air Flow Sensor with a Free-standing Micro-cantilever Structure.

PubMed

Wang, Yu-Hsiang; Lee, Chia-Yen; Chiang, Che-Ming

2007-10-17

This paper presents a micro-scale air flow sensor based on a free-standingcantilever structure. In the fabrication process, MEMS techniques are used to deposit asilicon nitride layer on a silicon wafer. A platinum layer is deposited on the silicon nitridelayer to form a piezoresistor, and the resulting structure is then etched to create afreestanding micro-cantilever. When an air flow passes over the surface of the cantileverbeam, the beam deflects in the downward direction, resulting in a small variation in theresistance of the piezoelectric layer. The air flow velocity is determined by measuring thechange in resistance using an external LCR meter. The experimental results indicate that theflow sensor has a high sensitivity (0.0284 ω/ms -1 ), a high velocity measurement limit (45ms -1 ) and a rapid response time (0.53 s).

Flow-Visualization Techniques Used at High Speed by Configuration Aerodynamics Wind-Tunnel-Test Team

NASA Technical Reports Server (NTRS)

Lamar, John E. (Editor)

2001-01-01

This paper summarizes a variety of optically based flow-visualization techniques used for high-speed research by the Configuration Aerodynamics Wind-Tunnel Test Team of the High-Speed Research Program during its tenure. The work of other national experts is included for completeness. Details of each technique with applications and status in various national wind tunnels are given.

Satellite-driven modeling approach for monitoring lava flow hazards during the 2017 Etna eruption

NASA Astrophysics Data System (ADS)

Del Negro, C.; Bilotta, G.; Cappello, A.; Ganci, G.; Herault, A.; Zago, V.

2017-12-01

The integration of satellite data and modeling represents an efficient strategy that may provide immediate answers to the main issues raised at the onset of a new effusive eruption. Satellite-based thermal remote sensing of hotspots related to effusive activity can effectively provide a variety of products suited to timing, locating, and tracking the radiant character of lava flows. Hotspots show the location and occurrence of eruptive events (vents). Discharge rate estimates may indicate the current intensity (effusion rate) and potential magnitude (volume). High-spatial resolution multispectral satellite data can complement field observations for monitoring the front position (length) and extension of flows (area). Physics-based models driven, or validated, by satellite-derived parameters are now capable of fast and accurate forecast of lava flow inundation scenarios (hazard). Here, we demonstrate the potential of the integrated application of satellite remote-sensing techniques and lava flow models during the 2017 effusive eruption at Mount Etna in Italy. This combined approach provided insights into lava flow field evolution by supplying detailed views of flow field construction (e.g., the opening of ephemeral vents) that were useful for more accurate and reliable forecasts of eruptive activity. Moreover, we gave a detailed chronology of the lava flow activity based on field observations and satellite images, assessed the potential extent of impacted areas, mapped the evolution of lava flow field, and executed hazard projections. The underside of this combination is the high sensitivity of lava flow inundation scenarios to uncertainties in vent location, discharge rate, and other parameters, which can make interpreting hazard forecasts difficult during an effusive crisis. However, such integration at last makes timely forecasts of lava flow hazards during effusive crises possible at the great majority of volcanoes for which no monitoring exists.

Unstructured and adaptive mesh generation for high Reynolds number viscous flows

NASA Technical Reports Server (NTRS)

Mavriplis, Dimitri J.

1991-01-01

A method for generating and adaptively refining a highly stretched unstructured mesh suitable for the computation of high-Reynolds-number viscous flows about arbitrary two-dimensional geometries was developed. The method is based on the Delaunay triangulation of a predetermined set of points and employs a local mapping in order to achieve the high stretching rates required in the boundary-layer and wake regions. The initial mesh-point distribution is determined in a geometry-adaptive manner which clusters points in regions of high curvature and sharp corners. Adaptive mesh refinement is achieved by adding new points in regions of large flow gradients, and locally retriangulating; thus, obviating the need for global mesh regeneration. Initial and adapted meshes about complex multi-element airfoil geometries are shown and compressible flow solutions are computed on these meshes.

Development and numerical analysis of low specific speed mixed-flow pump

NASA Astrophysics Data System (ADS)

Li, H. F.; Huo, Y. W.; Pan, Z. B.; Zhou, W. C.; He, M. H.

2012-11-01

With the development of the city, the market of the mixed flow pump with large flux and high head is prospect. The KSB Shanghai Pump Co., LTD decided to develop low speed specific speed mixed flow pump to meet the market requirements. Based on the centrifugal pump and axial flow pump model, aiming at the characteristics of large flux and high head, a new type of guide vane mixed flow pump was designed. The computational fluid dynamics method was adopted to analyze the internal flow of the new type model and predict its performances. The time-averaged Navier-Stokes equations were closed by SST k-ω turbulent model to adapt internal flow of guide vane with larger curvatures. The multi-reference frame(MRF) method was used to deal with the coupling of rotating impeller and static guide vane, and the SIMPLEC method was adopted to achieve the coupling solution of velocity and pressure. The computational results shows that there is great flow impact on the head of vanes at different working conditions, and there is great flow separation at the tailing of the guide vanes at different working conditions, and all will affect the performance of pump. Based on the computational results, optimizations were carried out to decrease the impact on the head of vanes and flow separation at the tailing of the guide vanes. The optimized model was simulated and its performance was predicted. The computational results show that the impact on the head of vanes and the separation at the tailing of the guide vanes disappeared. The high efficiency of the optimized pump is wide, and it fit the original design destination. The newly designed mixed flow pump is now in modeling and its experimental performance will be getting soon.

Power Grid Maintenance Scheduling Intelligence Arrangement Supporting System Based on Power Flow Forecasting

NASA Astrophysics Data System (ADS)

Xie, Chang; Wen, Jing; Liu, Wenying; Wang, Jiaming

With the development of intelligent dispatching, the intelligence level of network control center full-service urgent need to raise. As an important daily work of network control center, the application of maintenance scheduling intelligent arrangement to achieve high-quality and safety operation of power grid is very important. By analyzing the shortages of the traditional maintenance scheduling software, this paper designs a power grid maintenance scheduling intelligence arrangement supporting system based on power flow forecasting, which uses the advanced technologies in maintenance scheduling, such as artificial intelligence, online security checking, intelligent visualization techniques. It implements the online security checking of maintenance scheduling based on power flow forecasting and power flow adjusting based on visualization, in order to make the maintenance scheduling arrangement moreintelligent and visual.

Water-quality assessment of the eastern Iowa basins- nitrogen, phosphorus, suspended sediment, and organic carbon in surface water, 1996-98

USGS Publications Warehouse

Becher, Kent D.; Kalkhoff, Stephen J.; Schnoebelen, Douglas J.; Barnes, Kimberlee K.; Miller, Von E.

2001-01-01

Synoptic samples collected during low and high base flow had nitrogen, phosphorus, and organic-carbon concentrations that varied spatially and seasonally. Comparisons of water-quality data from six basic-fixed sampling sites and 19 other synoptic sites suggest that the water-quality data from basic-fixed sampling sites were representative of the entire study unit during periods of low and high base flow when most streamflow originates from ground water.

Webcam-based flow cytometer using wide-field imaging for low cell number detection at high throughput.

PubMed

Balsam, Joshua; Bruck, Hugh Alan; Rasooly, Avraham

2014-09-07

Here we describe a novel low-cost flow cytometer based on a webcam capable of low cell number detection in a large volume which may overcome the limitations of current flow cytometry. Several key elements have been combined to yield both high throughput and high sensitivity. The first element is a commercially available webcam capable of 187 frames per second video capture at a resolution of 320 × 240 pixels. The second element in this design is a 1 W 450 nm laser module for area-excitation, which combined with the webcam allows for rapid interrogation of a flow field. The final element is a 2D flow-cell which overcomes the flow limitation of hydrodynamic focusing and allows for higher sample throughput in a wider flow field. This cell allows for the linear velocity of target cells to be lower than in a conventional "1D" hydrodynamic focusing flow-cells typically used in cytometry at similar volumetric flow rates. It also allows cells to be imaged at the full frame rate of the webcam. Using this webcam-based flow cytometer with wide-field imaging, it was confirmed that the detection of fluorescently tagged 5 μm polystyrene beads in "1D" hydrodynamic focusing flow-cells was not practical for low cell number detection due to streaking from the motion of the beads, which did not occur with the 2D flow-cell design. The sensitivity and throughput of this webcam-based flow cytometer was then investigated using THP-1 human monocytes stained with SYTO-9 florescent dye in the 2D flow-cell. The flow cytometer was found to be capable of detecting fluorescently tagged cells at concentrations as low as 1 cell per mL at flow rates of 500 μL min(-1) in buffer and in blood. The effectiveness of detection was concentration dependent: at 100 cells per mL 84% of the cells were detected compared to microscopy, 10 cells per mL 79% detected and 1 cell per mL 59% of the cells were detected. With the blood samples spiked to 100 cells per mL, the average concentration for all samples was 91.4 cells per mL, with a 95% confidence interval of 86-97 cells per mL. These low cell concentrations and the large volume capabilities of the system may overcome the limitations of current cytometry, and are applicable to rare cell (such as circulating tumor cell) detection The simplicity and low cost of this device suggests that it may have a potential use in developing point-of-care clinical flow cytometry for resource-poor settings associated with global health.

Overland Flow Analysis Using Time Series of Suas-Derived Elevation Models

NASA Astrophysics Data System (ADS)

Jeziorska, J.; Mitasova, H.; Petrasova, A.; Petras, V.; Divakaran, D.; Zajkowski, T.

2016-06-01

With the advent of the innovative techniques for generating high temporal and spatial resolution terrain models from Unmanned Aerial Systems (UAS) imagery, it has become possible to precisely map overland flow patterns. Furthermore, the process has become more affordable and efficient through the coupling of small UAS (sUAS) that are easily deployed with Structure from Motion (SfM) algorithms that can efficiently derive 3D data from RGB imagery captured with consumer grade cameras. We propose applying the robust overland flow algorithm based on the path sampling technique for mapping flow paths in the arable land on a small test site in Raleigh, North Carolina. By comparing a time series of five flights in 2015 with the results of a simulation based on the most recent lidar derived DEM (2013), we show that the sUAS based data is suitable for overland flow predictions and has several advantages over the lidar data. The sUAS based data captures preferential flow along tillage and more accurately represents gullies. Furthermore the simulated water flow patterns over the sUAS based terrain models are consistent throughout the year. When terrain models are reconstructed only from sUAS captured RGB imagery, however, water flow modeling is only appropriate in areas with sparse or no vegetation cover.

Evolution of finite-amplitude localized vortices in planar homogeneous shear flows

NASA Astrophysics Data System (ADS)

Karp, Michael; Shukhman, Ilia G.; Cohen, Jacob

2017-02-01

An analytical-based method is utilized to follow the evolution of localized initially Gaussian disturbances in flows with homogeneous shear, in which the base velocity components are at most linear functions of the coordinates, including hyperbolic, elliptic, and simple shear. Coherent structures, including counterrotating vortex pairs (CVPs) and hairpin vortices, are formed for the cases where the streamlines of the base flow are open (hyperbolic and simple shear). For hyperbolic base flows, the dominance of shear over rotation leads to elongation of the localized disturbance along the outlet asymptote and formation of CVPs. For simple shear CVPs are formed from linear and nonlinear disturbances, whereas hairpins are observed only for highly nonlinear disturbances. For elliptic base flows CVPs, hairpins and vortex loops form initially, however they do not last and break into various vortical structures that spread in the spanwise direction. The effect of the disturbance's initial amplitude and orientation is examined and the optimal orientation achieving maximal growth is identified.

Trends and shifts in streamflow in Hawaii, 1913-2008

USGS Publications Warehouse

Bassiouni, Maoya; Oki, Delwyn S.

2013-01-01

This study addresses a need to document changes in streamflow and base flow (groundwater discharge to streams) in Hawai'i during the past century. Statistically significant long-term (1913-2008) downward trends were detected (using the nonparametric Mann-Kendall test) in low-streamflow and base-flow records. These long-term downward trends are likely related to a statistically significant downward shift around 1943 detected (using the nonparametric Pettitt test) in index records of streamflow and base flow. The downward shift corresponds to a decrease of 22% in median streamflow and a decrease of 23% in median base flow between the periods 1913-1943 and 1943-2008. The shift coincides with other local and regional factors, including a change from a positive to a negative phase in the Pacific Decadal Oscillation, shifts in the direction of the trade winds over Hawai'i, and a reforestation programme. The detected shift and long-term trends reflect region-wide changes in climatic and land-cover factors. A weak pattern of downward trends in base flows during the period 1943-2008 may indicate a continued decrease in base flows after the 1943 shift. Downward trends were detected more commonly in base-flow records than in high-streamflow, peak-flow, and rainfall records. The decrease in base flow is likely related to a decrease in groundwater storage and recharge and therefore is a valuable indicator of decreasing water availability and watershed vulnerability to hydrologic changes. Whether the downward trends will continue is largely uncertain given the uncertainty in climate-change projections and watershed responses to changes.

Flow structure and unsteadiness in the supersonic wake of a generic space launcher

NASA Astrophysics Data System (ADS)

Schreyer, Anne-Marie; Stephan, Sören; Radespiel, Rolf

2015-11-01

At the junction between the rocket engine and the main body of a classical space launcher, a separation-dominated and highly unstable flow field develops and induces strong wall-pressure oscillations. These can excite structural vibrations detrimental to the launcher. It is desirable to minimize these effects, for which a better understanding of the flow field is required. We study the wake flow of a generic axisymmetric space-launcher model with and without propulsive jet (cold air). Experimental investigations are performed at Mach 2.9 and a Reynolds number ReD = 1 . 3 .106 based on model diameter D. The jet exits the nozzle at Mach 2.5. Velocity measurements by means of Particle Image Velocimetry and mean and unsteady wall-pressure measurements on the main-body base are performed simultaneously. Additionally, we performed hot-wire measurements at selected points in the wake. We can thus observe the evolution of the wake flow along with its spectral content. We describe the mean and turbulent flow topology and evolution of the structures in the wake flow and discuss the origin of characteristic frequencies observed in the pressure signal at the launcher base. The influence of a propulsive jet on the evolution and topology of the wake flow is discussed in detail. The German Research Foundation DFG is gratefully acknowledged for funding this research within the SFB-TR40 ``Technological foundations for the design of thermally and mechanically highly loaded components of future space transportation systems.''

High Average Power Laser Gain Medium With Low Optical Distortion Using A Transverse Flowing Liquid Host

DOEpatents

Comaskey, Brian J.; Ault, Earl R.; Kuklo, Thomas C.

2005-07-05

A high average power, low optical distortion laser gain media is based on a flowing liquid media. A diode laser pumping device with tailored irradiance excites the laser active atom, ion or molecule within the liquid media. A laser active component of the liquid media exhibits energy storage times longer than or comparable to the thermal optical response time of the liquid. A circulation system that provides a closed loop for mixing and circulating the lasing liquid into and out of the optical cavity includes a pump, a diffuser, and a heat exchanger. A liquid flow gain cell includes flow straighteners and flow channel compression.

Advanced Laser-Based Techniques for Gas-Phase Diagnostics in Combustion and Aerospace Engineering.

PubMed

Ehn, Andreas; Zhu, Jiajian; Li, Xuesong; Kiefer, Johannes

2017-03-01

Gaining information of species, temperature, and velocity distributions in turbulent combustion and high-speed reactive flows is challenging, particularly for conducting measurements without influencing the experimental object itself. The use of optical and spectroscopic techniques, and in particular laser-based diagnostics, has shown outstanding abilities for performing non-intrusive in situ diagnostics. The development of instrumentation, such as robust lasers with high pulse energy, ultra-short pulse duration, and high repetition rate along with digitized cameras exhibiting high sensitivity, large dynamic range, and frame rates on the order of MHz, has opened up for temporally and spatially resolved volumetric measurements of extreme dynamics and complexities. The aim of this article is to present selected important laser-based techniques for gas-phase diagnostics focusing on their applications in combustion and aerospace engineering. Applicable laser-based techniques for investigations of turbulent flows and combustion such as planar laser-induced fluorescence, Raman and Rayleigh scattering, coherent anti-Stokes Raman scattering, laser-induced grating scattering, particle image velocimetry, laser Doppler anemometry, and tomographic imaging are reviewed and described with some background physics. In addition, demands on instrumentation are further discussed to give insight in the possibilities that are offered by laser flow diagnostics.

An auxiliary method to reduce potential adverse impacts of projected land developments: subwatershed prioritization.

PubMed

Kalin, Latif; Hantush, Mohamed M

2009-02-01

An index based method is developed that ranks the subwatersheds of a watershed based on their relative impacts on watershed response to anticipated land developments, and then applied to an urbanizing watershed in Eastern Pennsylvania. Simulations with a semi-distributed hydrologic model show that computed low- and high-flow frequencies at the main outlet increase significantly with the projected landscape changes in the watershed. The developed index is utilized to prioritize areas in the urbanizing watershed based on their contributions to alterations in the magnitude of selected flow characteristics at two spatial resolutions. The low-flow measure, 7Q10, rankings are shown to mimic the spatial trend of groundwater recharge rates, whereas average annual maximum daily flow, QAMAX, and average monthly median of daily flows, QMMED, rankings are influenced by both recharge and proximity to watershed outlet. Results indicate that, especially with the higher resolution, areas having quicker responses are not necessarily the more critical areas for high-flow scenarios. Subwatershed rankings are shown to vary slightly with the location of water quality/quantity criteria enforcement. It is also found that rankings of subwatersheds upstream from the site of interest, which could be the main outlet or any interior point in the watershed, may be influenced by the time scale of the hydrologic processes.

An experimental investigation of the flow physics of high-lift systems

NASA Technical Reports Server (NTRS)

Thomas, Flint O.; Nelson, R. C.

1995-01-01

This progress report, a series of viewgraphs, outlines experiments on the flow physics of confluent boundary layers for high lift systems. The design objective is to design high lift systems with improved C(sub Lmax) for landing approach and improved take-off L/D and simultaneously reduce acquisition and maintenance costs. In effect, achieve improved performance with simpler designs. The research objectives include: establish the role of confluent boundary layer flow physics in high-lift production; contrast confluent boundary layer structure for optimum and non-optimum C(sub L) cases; formation of a high quality, detailed archival data base for CFD/modeling; and examination of the role of relaminarization and streamline curvature.

Modeling Coherent Structures in Canopy Flows

NASA Astrophysics Data System (ADS)

Luhar, Mitul

2017-11-01

It is well known that flows over vegetation canopies are characterized by the presence of energetic coherent structures. Since the mean profile over dense canopies exhibits an inflection point, the emergence of such structures is often attributed to a Kelvin-Helmholtz instability. However, though stability analyses provide useful mechanistic insights into canopy flows, they are limited in their ability to generate predictions for spectra and coherent structure. The present effort seeks to address this limitation by extending the resolvent formulation (McKeon and Sharma, 2010, J. Fluid Mech.) to canopy flows. Under the resolvent formulation, the turbulent velocity field is expressed as a superposition of propagating modes, identified via a gain-based (singular value) decomposition of the Navier-Stokes equations. A key advantage of this approach is that it reconciles multiple mechanisms that lead to high amplification in turbulent flows, including modal instability, transient growth, and critical-layer phenomena. Further, individual high-gain modes can be combined to generate more complete models for coherent structure and velocity spectra. Preliminary resolvent-based model predictions for canopy flows agree well with existing experiments and simulations.

Flowable Conducting Particle Networks in Redox-Active Electrolytes for Grid Energy Storage

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hatzell, K. B.; Boota, M.; Kumbur, E. C.

2015-01-01

This study reports a new hybrid approach toward achieving high volumetric energy and power densities in an electrochemical flow capacitor for grid energy storage. The electrochemical flow capacitor suffers from high self-discharge and low energy density because charge storage is limited to the available surface area (electric double layer charge storage). Here, we examine two carbon materials as conducting particles in a flow battery electrolyte containing the VO2+/VO2+ redox couple. Highly porous activated carbon spheres (CSs) and multi-walled carbon nanotubes (MWCNTs) are investigated as conducting particle networks that facilitate both faradaic and electric double layer charge storage. Charge storage contributionsmore » (electric double layer and faradaic) are distinguished for flow-electrodes composed of MWCNTs and activated CSs. A MWCNT flow-electrode based in a redox-active electrolyte containing the VO2+/VO2+ redox couple demonstrates 18% less self-discharge, 10 X more energy density, and 20 X greater power densities (at 20 mV s-1) than one based on a non-redox active electrolyte. Furthermore, a MWCNT redox-active flow electrode demonstrates 80% capacitance retention, and >95% coulombic efficiency over 100 cycles, indicating the feasibility of utilizing conducting networks with redox chemistries for grid energy storage.« less

Flowable conducting particle networks in redox-active electrolytes for grid energy storage

DOE PAGES

Hatzell, K. B.; Boota, M.; Kumbur, E. C.; ...

2015-01-09

This paper reports a new hybrid approach toward achieving high volumetric energy and power densities in an electrochemical flow capacitor for grid energy storage. The electrochemical flow capacitor suffers from high self-discharge and low energy density because charge storage is limited to the available surface area (electric double layer charge storage). Here, we examine two carbon materials as conducting particles in a flow battery electrolyte containing the VO 2+/VO 2 + redox couple. Highly porous activated carbon spheres (CSs) and multi-walled carbon nanotubes (MWCNTs) are investigated as conducting particle networks that facilitate both faradaic and electric double layer charge storage.more » Charge storage contributions (electric double layer and faradaic) are distinguished for flow-electrodes composed of MWCNTs and activated CSs. A MWCNT flow-electrode based in a redox-active electrolyte containing the VO 2+/VO 2 + redox couple demonstrates 18% less self-discharge, 10 X more energy density, and 20 X greater power densities (at 20 mV s -1) than one based on a non-redox active electrolyte. Additionally, a MWCNT redox-active flow electrode demonstrates 80% capacitance retention, and >95% coulombic efficiency over 100 cycles, indicating the feasibility of utilizing conducting networks with redox chemistries for grid energy storage.« less

Coherent flow structures and heat transfer in a duct with electromagnetic forcing

NASA Astrophysics Data System (ADS)

Himo, Rawad; Habchi, Charbel

2018-04-01

Coherent vortices are generated electromagnetically in a square duct flow. The vortices are induced by a Lorentz force applied in a small section near the entrance of the duct. The flow structure complexity increases with the electromagnetic forcing since the primary vortices propagating along the duct detach to generate secondary smaller streamwise vortices and hairpin-like structures. The Reynolds number based on the mean flow velocity and hydraulic diameter is 500, and five cases were studied by varying the electromagnetic forcing. Even though this Reynolds number is relatively low, a periodic sequence of hairpin-like structure flow was observed for the high forcing cases. This mechanism enhances the mixing process between the different flow regions resulting in an increase in the thermal performances which reaches 66% relative to the duct flow without forcing. In addition to the flow complexity, lower forcing cases remained steady, unlike high Lorentz forces that induced periodic instabilities with a Strouhal number around 0.59 for the transient eddies. The effect of the flow structure on the heat transfer is analyzed qualitatively and quantitatively using numerical simulations based on the finite volume method. Moreover, proper orthogonal decomposition (POD) analysis was performed on the flow structures to evaluate the most energetic modes contributing in the flow. It is found from the POD analysis that the primary streamwise vortices and hairpin legs are the flow structures that are the most contributing to the heat transfer process.

Monitoring of surface velocity of hyper-concentrated flow in a laboratory flume by means of fully-digital PIV

NASA Astrophysics Data System (ADS)

Termini, Donatella; Di Leonardo, Alice

2016-04-01

High flow conditions, which are generally characterized by high sediment concentrations, do not permit the use of traditional measurement equipment. Traditional techniques usually are based on the intrusive measure of the vertical profile of flow velocity and on the linking of water depth with the discharge through the rating curve. The major disadvantage of these measurement techniques is that they are difficult to use and not safe for operators especially in high flow conditions. The point is that, as literature shows (see as an example Moramarco and Termini, 2015), especially in such conditions, the measurement of surface velocity distribution is important to evaluate the mean flow velocity and, thus, the flow discharge. In the last decade, image-based techniques have been increasingly used for surface velocity measurements (among others Joeau et al., 2008). Experimental program has been recently conducted at the Hydraulic laboratory of the Department of Civil, Environmental, Aerospatial and of Materials Engineering (DICAM) - University of Palermo (Italy) in order to analyze the propagation phenomenon of hyper-concentrated flow in a defense channel. The experimental apparatus includes a high-precision camera and a system allowing the images recording. This paper investigates the utility and the efficiency of the digital image-technique for remote monitoring of surface velocity in hyper-concentrated flow by the aid of data collected during experiments conducted in the laboratory flume. In particular the present paper attention is focused on the estimation procedure of the velocity vectors and on their sensitivity with parameters (number of images, spatial resolution of interrogation area,) of the images processing procedure. References Jodeau M., A. Hauet, A. Paquier, Le Coz J., Dramais G., Application and evaluation of LS-PIV technique for the monitoring of river surface in high flow conditions, Flow Measurements and Instrumentation, Vol.19, No.2, 2008, pp.117-127. Moramarco T., Termini D., Entropic approach to estimate the mean flow velocity: experimental investigation in laboratory flumes, Environmental Fluid mechanics, Vol. 15, No.1, 2015.

EuroFlow standardization of flow cytometer instrument settings and immunophenotyping protocols

PubMed Central

Kalina, T; Flores-Montero, J; van der Velden, V H J; Martin-Ayuso, M; Böttcher, S; Ritgen, M; Almeida, J; Lhermitte, L; Asnafi, V; Mendonça, A; de Tute, R; Cullen, M; Sedek, L; Vidriales, M B; Pérez, J J; te Marvelde, J G; Mejstrikova, E; Hrusak, O; Szczepański, T; van Dongen, J J M; Orfao, A

2012-01-01

The EU-supported EuroFlow Consortium aimed at innovation and standardization of immunophenotyping for diagnosis and classification of hematological malignancies by introducing 8-color flow cytometry with fully standardized laboratory procedures and antibody panels in order to achieve maximally comparable results among different laboratories. This required the selection of optimal combinations of compatible fluorochromes and the design and evaluation of adequate standard operating procedures (SOPs) for instrument setup, fluorescence compensation and sample preparation. Additionally, we developed software tools for the evaluation of individual antibody reagents and antibody panels. Each section describes what has been evaluated experimentally versus adopted based on existing data and experience. Multicentric evaluation demonstrated high levels of reproducibility based on strict implementation of the EuroFlow SOPs and antibody panels. Overall, the 6 years of extensive collaborative experiments and the analysis of hundreds of cell samples of patients and healthy controls in the EuroFlow centers have provided for the first time laboratory protocols and software tools for fully standardized 8-color flow cytometric immunophenotyping of normal and malignant leukocytes in bone marrow and blood; this has yielded highly comparable data sets, which can be integrated in a single database. PMID:22948490

A multilayer microdevice for cell-based high-throughput drug screening

NASA Astrophysics Data System (ADS)

Liu, Chong; Wang, Lei; Xu, Zheng; Li, Jingmin; Ding, Xiping; Wang, Qi; Chunyu, Li

2012-06-01

A multilayer polydimethylsiloxane microdevice for cell-based high-throughput drug screening is described in this paper. This established microdevice was based on a modularization method and it integrated a drug/medium concentration gradient generator (CGG), pneumatic microvalves and a cell culture microchamber array. The CGG was able to generate five steps of linear concentrations with the same outlet flow rate. The medium/drug flowed through CGG and then into the pear-shaped cell culture microchambers vertically. This vertical perfusion mode was used to reduce the impact of the shear stress on the physiology of cells induced by the fluid flow in the microchambers. Pear-shaped microchambers with two arrays of miropillars at each outlet were adopted in this microdevice, which were beneficial to cell distribution. The chemotherapeutics Cisplatin (DDP)-induced Cisplatin-resistant cell line A549/DDP apoptotic experiments were performed well on this platform. The results showed that this novel microdevice could not only provide well-defined and stable conditions for cell culture, but was also useful for cell-based high-throughput drug screening with less reagents and time consumption.

Impact of Climate Change and Human Intervention on River Flow Regimes

NASA Astrophysics Data System (ADS)

Singh, Rajendra; Mittal, Neha; Mishra, Ashok

2017-04-01

Climate change and human interventions like dam construction bring freshwater ecosystem under stress by changing flow regime. It is important to analyse their impact at a regional scale along with changes in the extremes of temperature and precipitation which further modify the flow regime components such as magnitude, timing, frequency, duration, and rate of change of flow. In this study, the Kangsabati river is chosen to analyse the hydrological alterations in its flow regime caused by dam, climate change and their combined impact using Soil and Water Assessment Tool (SWAT) and the Indicators of Hydrologic Alteration (IHA) program based on the Range of Variability Approach (RVA). Results show that flow variability is significantly reduced due to dam construction with high flows getting absorbed and pre-monsoon low flows being augmented by the reservoir. Climate change alone reduces the high peaks whereas a combination of dam and climate change significantly reduces variability by affecting both high and low flows, thereby further disrupting the functioning of riverine ecosystems. Analysis shows that in the Kangsabati basin, influence of dam is greater than that of the climate change, thereby emphasising the significance of direct human intervention. Keywords: Climate change, human impact, flow regime, Kangsabati river, SWAT, IHA, RVA.

Streamflow characteristics and trends in New Jersey, water years 1897-2003

USGS Publications Warehouse

Watson, Kara M.; Reiser, Robert G.; Nieswand, Steven P.; Schopp, Robert D.

2005-01-01

Streamflow statistics were computed for 111 continuous-record streamflow-gaging stations with 20 or more years of continuous record and for 500 low-flow partial-record stations, including 66 gaging stations with less than 20 years of continuous record. Daily mean streamflow data from water year 1897 through water year 2001 were used for the computations at the gaging stations. (The water year is the 12-month period, October 1 through September 30, designated by the calendar year in which it ends). The characteristics presented for the long-term continuous-record stations are daily streamflow, harmonic mean flow, flow frequency, daily flow durations, trend analysis, and streamflow variability. Low-flow statistics for gaging stations with less than 20 years of record and for partial-record stations were estimated by correlating base-flow measurements with daily mean flows at long-term (more than 20 years) continuous-record stations. Instantaneous streamflow measurements through water year 2003 were used to estimate low-flow statistics at the partial-record stations. The characteristics presented for partial-record stations are mean annual flow; harmonic mean flow; and annual and winter low-flow frequency. The annual 1-, 7-, and 30-day low- and high-flow data sets were tested for trends. The results of trend tests for high flows indicate relations between upward trends for high flows and stream regulation, and high flows and development in the basin. The relation between development and low-flow trends does not appear to be as strong as for development and high-flow trends. Monthly, seasonal, and annual precipitation data for selected long-term meteorological stations also were tested for trends to analyze the effects of climate. A significant upward trend in precipitation in northern New Jersey, Climate Division 1 was identified. For Climate Division 2, no general increase in average precipitation was observed. Trend test results indicate that high flows at undeveloped, unregulated sites have not been affected by the increase in average precipitation. The ratio of instantaneous peak flow to 3-day mean flow, ratios of flow duration, ratios of high-flow/low-flow frequency, and coefficient of variation were used to define streamflow variability. Streamflow variability was significantly greater among the group of gaging stations located outside the Coastal Plain than among the group of gaging stations located in the Coastal Plain.

Microelectrokinetic turbulence in microfluidics at low Reynolds number.

PubMed

Wang, Guiren; Yang, Fang; Zhao, Wei

2016-01-01

There is commonly no turbulence in microfluidics, and the flows are believed to be either laminar or chaotic, since Reynolds number (Re) in microflows is usually on the order of unity or lower. However, we recently demonstrated that it is possible to achieve turbulence with low Re (based on the measured flow velocity and the width of the channel entrance) when a pressure-driven flow is electrokinetically forced in a quasi T-microchannel. To be able to measure high frequency velocity fluctuations in microchannels, a velocimeter with submicrometer spatial resolution and microsecond temporal resolution, called a laser-induced fluorescence photobleaching anemometer, is developed. Here we characterize the microelectrokinetic turbulence and observe some typical and important features of high Re flows, such as Kolmogorov -5/3 spectrum of velocity fluctuation, which usually can be realized only at very high Re in macroturbulent flows.

Adaptive Numerical Dissipative Control in High Order Schemes for Multi-D Non-Ideal MHD

NASA Technical Reports Server (NTRS)

Yee, H. C.; Sjoegreen, B.

2004-01-01

The goal is to extend our adaptive numerical dissipation control in high order filter schemes and our new divergence-free methods for ideal MHD to non-ideal MHD that include viscosity and resistivity. The key idea consists of automatic detection of different flow features as distinct sensors to signal the appropriate type and amount of numerical dissipation/filter where needed and leave the rest of the region free of numerical dissipation contamination. These scheme-independent detectors are capable of distinguishing shocks/shears, flame sheets, turbulent fluctuations and spurious high-frequency oscillations. The detection algorithm is based on an artificial compression method (ACM) (for shocks/shears), and redundant multi-resolution wavelets (WAV) (for the above types of flow feature). These filter approaches also provide a natural and efficient way for the minimization of Div(B) numerical error. The filter scheme consists of spatially sixth order or higher non-dissipative spatial difference operators as the base scheme for the inviscid flux derivatives. If necessary, a small amount of high order linear dissipation is used to remove spurious high frequency oscillations. For example, an eighth-order centered linear dissipation (AD8) might be included in conjunction with a spatially sixth-order base scheme. The inviscid difference operator is applied twice for the viscous flux derivatives. After the completion of a full time step of the base scheme step, the solution is adaptively filtered by the product of a 'flow detector' and the 'nonlinear dissipative portion' of a high-resolution shock-capturing scheme. In addition, the scheme independent wavelet flow detector can be used in conjunction with spatially compact, spectral or spectral element type of base schemes. The ACM and wavelet filter schemes using the dissipative portion of a second-order shock-capturing scheme with sixth-order spatial central base scheme for both the inviscid and viscous MHD flux derivatives and a fourth-order Runge-Kutta method are denoted.

Functional language and data flow architectures

NASA Technical Reports Server (NTRS)

Ercegovac, M. D.; Patel, D. R.; Lang, T.

1983-01-01

This is a tutorial article about language and architecture approaches for highly concurrent computer systems based on the functional style of programming. The discussion concentrates on the basic aspects of functional languages, and sequencing models such as data-flow, demand-driven and reduction which are essential at the machine organization level. Several examples of highly concurrent machines are described.

Computational Aeroacoustic Analysis of Slat Trailing-Edge Flow

NASA Technical Reports Server (NTRS)

Singer, Bart A.; Lockard, David P.; Brentner, Kenneth S.; Khorrami, Mehdi R.; Berkman, Mert E.; Choudhari, Meelan

2000-01-01

An acoustic analysis based on the Ffowcs Williams and Hawkings equation was performed for a high-lift system. As input, the acoustic analysis used un- steady flow data obtained from a highly resolved, time-dependent, Reynolds-averaged Navier-Stokes calculation. The analysis strongly suggests that vor- tex shedding from the trailing edge of the slat results in a high-amplitude, high-frequency acoustic signal, similar to that which was observed in a correspond- ing experimental study of the high-lift system.

Abnormal high surface heat flow caused by the Emeishan mantle plume

NASA Astrophysics Data System (ADS)

Jiang, Qiang; Qiu, Nansheng; Zhu, Chuanqing

2016-04-01

It is commonly believed that increase of heat flow caused by a mantle plume is small and transient. Seafloor heat flow data near the Hawaiian hotspot and the Iceland are comparable to that for oceanic lithosphere elsewhere. Numerical modeling of the thermal effect of the Parana large igneous province shows that the added heat flow at the surface caused by the magmatic underplating is less than 5mW/m2. However, the thermal effect of Emeishan mantle plume (EMP) may cause the surface hear-flow abnormally high. The Middle-Late Emeishan mantle plume is located in the western Yangtze Craton. The Sichuan basin, to the northeast of the EMP, is a superimposed basin composed of Paleozoic marine carbonate rocks and Mesozoic-Cenozoic terrestrial clastic rocks. The vitrinite reflectance (Ro) data as a paleogeothermal indicator records an apparent change of thermal regime of the Sichuan basin. The Ro profiles from boreholes and outcrops which are close to the center of the basalt province exhibit a 'dog-leg' style at the unconformity between the Middle and Upper Permian, and they show significantly higher gradients in the lower subsection (pre-Middle Permian) than the Upper subsection (Upper Permian to Mesozoic). Thermal history inversion based on these Ro data shows that the lower subsection experienced a heat flow peak much higher than that of the upper subsection. The abnormal heat flow in the Sichuan basin is consistent with the EMP in temporal and spatial distribution. The high-temperature magmas from deep mantle brought heat to the base of the lithosphere, and then large amount of heat was conducted upwards, resulting in the abnormal high surface heat flow.

The Gravity of High-Skilled Migration Policies.

PubMed

Czaika, Mathias; Parsons, Christopher R

2017-04-01

Combining unique, annual, bilateral data on labor flows of highly skilled immigrants for 10 OECD destinations between 2000 and 2012, with new databases comprising both unilateral and bilateral policy instruments, we present the first judicious cross-country assessment of policies aimed to attract and select high-skilled workers. Points-based systems are much more effective in attracting and selecting high-skilled migrants than requiring a job offer, labor market tests, and shortage lists. Offers of permanent residency, while attracting the highly skilled, overall reduce the human capital content of labor flows because they prove more attractive to non-high-skilled workers. Bilateral recognition of diploma and social security agreements foster greater flows of high-skilled workers and improve the skill selectivity of immigrant flows. Conversely, double taxation agreements deter high-skilled migrants, although they do not alter overall skill selectivity. Our results are robust to a variety of empirical specifications that account for destination-specific amenities, multilateral resistance to migration, and the endogeneity of immigration policies.

Numerical investigation of hub clearance flow in a Kaplan turbine

NASA Astrophysics Data System (ADS)

Wu, H.; Feng, J. J.; Wu, G. K.; Luo, X. Q.

2012-11-01

In this paper, the flow field considering the hub clearance flow in a Kaplan turbine has been investigated through using the commercial CFD code ANSYS CFX based on high-quality structured grids generated by ANSYS ICEM CFD. The turbulence is simulated by k-ω based shear stress transport (SST) turbulence model together with automatic near wall treatments. Four kinds of simulations have been conducted for the runner geometry without hub clearance, with only the hub front clearance, with only the rear hub clearance, and with both front and rear clearance. The analysis of the obtained results is focused on the flow structure of the hub clearance flow, the effect on the turbine performance including hydraulic efficiency and cavitation performance, which can improve the understanding on the flow field in a Kaplan turbine.

Relation between ground water and surface water in Brandywine Creek basin, Pennsylvania

USGS Publications Warehouse

Olmsted, F.H.; Hely, A.G.

1962-01-01

The relation between ground water and surface water was studied in Brandywine Creek basin, an area of 287 square miles in the Piedmont physiographic province in southeastern Pennsylvania. Most of the basin is underlain by crystalline rocks that yield only small to moderate supplies of water to wells, but the creek has an unusually well-sustained base flow. Streamflow records for the Chadds Ford, Pa., gaging station were analyzed; base flow recession curves and hydrographs of base flow were defined for the calendar years 1928-31 and 1952-53. Water budgets calculated for these two periods indicate that about two-thirds of the runoff of Brandywine Creek is base flow--a significantly higher proportion of base flow than in streams draining most other types of consolidated rocks in the region and almost as high as in streams in sandy parts of the Coastal Plain province in New Jersey and Delaware. Ground-water levels in 16 observation wells were compared with the base flow of the creek for 1952-53. The wells are assumed to provide a reasonably good sample of average fluctuations of the water table and its depth below the land surface. Three of the wells having the most suitable records were selected as index wells to use in a more detailed analysis. A direct, linear relation between the monthly average ground-water stage in the index wells and the base flow of the creek in winter months was found. The average ground-water discharge in the basin for 1952-53 was 489 cfs (316 mgd), of which slightly less than one-fourth was estimated to be loss by evapotranspiration. However, the estimated evapotranspiration from ground water, and consequently the estimated total ground-water discharge, may be somewhat high. The average gravity yield (short-term coefficient of storage) of the zone of water-table fluctuation was calculated by two methods. The first method, based on the ratio of change in ground-water storage as calculated from a witner base-flow recession curve is seasonal change in ground-water stage in the observation wells, gave values of about 7 percent using 16 wells) and 7 1/2 percent (using 3 index wells). The second method, in which the change in ground water storage is based on a hypothetical base-flow recession curve (derived from the observed linear relation between ground-water stage in the index wells and base flow), gave a value of about 10 1/2 percent. The most probable value of gravity yield is between 7 1/2 and 10 percent, but this estimate may require modification when more information on the average magnitude of water-table fluctuation and the sources of base flow of the creek become available. Rough estimates were made of the average coefficient of transmissibility of the rocks in the basin by use of the estimated total ground-water discharge for the period 1952-53, approximate values of length of discharge areas, and average water-table gradients adjacent to the discharge areas. The estimated average coefficient of transmissibility for 1952-53 is roughly 1,000 gpd per foot. The transmissibility is variable, decreasing with decreasing ground-water stage. The seeming inconsistency between the small to moderate ground-water yield to wells and the high yield to streams is explained in terms of the deep permeable soils, the relatively high gravity yield of the zone of water-table fluctuation, the steep water-table gradients toward the streams, the relatively low transmissibility of the rocks, and the rapid decreases in gravity yield below the lower limit of water-table fluctuation. It is concluded that no simple relation exists between the amount of natural ground-water discharge in an area and all the proportion of this discharge that can be diverted to wells.

In Vitro MRV-based Hemodynamic Study of Complex Helical Flow in a Patient-specific Jugular Model

NASA Astrophysics Data System (ADS)

Kefayati, Sarah; Acevedo-Bolton, Gabriel; Haraldsson, Henrik; Saloner, David

2014-11-01

Neurointerventional Radiologists are frequently requested to evaluate the venous side of the intracranial circulation for a variety of conditions including: Chronic Cerebrospinal Venous Insufficiency thought to play a role in the development of multiple sclerosis; sigmoid sinus diverticulum which has been linked to the presence of pulsatile tinnitus; and jugular vein distension which is related to cardiac dysfunction. Most approaches to evaluating these conditions rely on structural assessment or two dimensional flow analyses. This study was designed to investigate the highly complex jugular flow conditions using magnetic resonance velocimetry (MRV). A jugular phantom was fabricated based on the geometry of the dominant jugular in a tinnitus patient. Volumetric three-component time-resolved velocity fields were obtained using 4D PC-MRI -with the protocol enabling turbulence acquisition- and the patient-specific pulsatile waveform. Flow was highly complex exhibiting regions of jet, high swirling strength, and strong helical pattern with the core originating from the focal point of the jugular bulb. Specifically, flow was analyzed for helicity and the level of turbulence kinetic energy elevated in the core of helix and distally, in the post-narrowing region.

Diffuse flow environments within basalt- and sediment-based hydrothermal vent ecosystems harbor specialized microbial communities.

PubMed

Campbell, Barbara J; Polson, Shawn W; Zeigler Allen, Lisa; Williamson, Shannon J; Lee, Charles K; Wommack, K Eric; Cary, S Craig

2013-01-01

Hydrothermal vents differ both in surface input and subsurface geochemistry. The effects of these differences on their microbial communities are not clear. Here, we investigated both alpha and beta diversity of diffuse flow-associated microbial communities emanating from vents at a basalt-based hydrothermal system along the East Pacific Rise (EPR) and a sediment-based hydrothermal system, Guaymas Basin. Both Bacteria and Archaea were targeted using high throughput 16S rRNA gene pyrosequencing analyses. A unique aspect of this study was the use of a universal set of 16S rRNA gene primers to characterize total and diffuse flow-specific microbial communities from varied deep-sea hydrothermal environments. Both surrounding seawater and diffuse flow water samples contained large numbers of Marine Group I (MGI) Thaumarchaea and Gammaproteobacteria taxa previously observed in deep-sea systems. However, these taxa were geographically distinct and segregated according to type of spreading center. Diffuse flow microbial community profiles were highly differentiated. In particular, EPR dominant diffuse flow taxa were most closely associated with chemolithoautotrophs, and off axis water was dominated by heterotrophic-related taxa, whereas the opposite was true for Guaymas Basin. The diversity and richness of diffuse flow-specific microbial communities were strongly correlated to the relative abundance of Epsilonproteobacteria, proximity to macrofauna, and hydrothermal system type. Archaeal diversity was higher than or equivalent to bacterial diversity in about one third of the samples. Most diffuse flow-specific communities were dominated by OTUs associated with Epsilonproteobacteria, but many of the Guaymas Basin diffuse flow samples were dominated by either OTUs within the Planctomycetes or hyperthermophilic Archaea. This study emphasizes the unique microbial communities associated with geochemically and geographically distinct hydrothermal diffuse flow environments.

Diffuse flow environments within basalt- and sediment-based hydrothermal vent ecosystems harbor specialized microbial communities

PubMed Central

Campbell, Barbara J.; Polson, Shawn W.; Zeigler Allen, Lisa; Williamson, Shannon J.; Lee, Charles K.; Wommack, K. Eric; Cary, S. Craig

2013-01-01

Hydrothermal vents differ both in surface input and subsurface geochemistry. The effects of these differences on their microbial communities are not clear. Here, we investigated both alpha and beta diversity of diffuse flow-associated microbial communities emanating from vents at a basalt-based hydrothermal system along the East Pacific Rise (EPR) and a sediment-based hydrothermal system, Guaymas Basin. Both Bacteria and Archaea were targeted using high throughput 16S rRNA gene pyrosequencing analyses. A unique aspect of this study was the use of a universal set of 16S rRNA gene primers to characterize total and diffuse flow-specific microbial communities from varied deep-sea hydrothermal environments. Both surrounding seawater and diffuse flow water samples contained large numbers of Marine Group I (MGI) Thaumarchaea and Gammaproteobacteria taxa previously observed in deep-sea systems. However, these taxa were geographically distinct and segregated according to type of spreading center. Diffuse flow microbial community profiles were highly differentiated. In particular, EPR dominant diffuse flow taxa were most closely associated with chemolithoautotrophs, and off axis water was dominated by heterotrophic-related taxa, whereas the opposite was true for Guaymas Basin. The diversity and richness of diffuse flow-specific microbial communities were strongly correlated to the relative abundance of Epsilonproteobacteria, proximity to macrofauna, and hydrothermal system type. Archaeal diversity was higher than or equivalent to bacterial diversity in about one third of the samples. Most diffuse flow-specific communities were dominated by OTUs associated with Epsilonproteobacteria, but many of the Guaymas Basin diffuse flow samples were dominated by either OTUs within the Planctomycetes or hyperthermophilic Archaea. This study emphasizes the unique microbial communities associated with geochemically and geographically distinct hydrothermal diffuse flow environments. PMID:23898323

Quantifying the fate of agricultural nitrogen in an unconfined aquifer: Stream-based observations at three measurement scales

NASA Astrophysics Data System (ADS)

Gilmore, Troy E.; Genereux, David P.; Solomon, D. Kip; Solder, John E.; Kimball, Briant A.; Mitasova, Helena; Birgand, François

2016-03-01

We compared three stream-based sampling methods to study the fate of nitrate in groundwater in a coastal plain watershed: point measurements beneath the streambed, seepage blankets (novel seepage-meter design), and reach mass-balance. The methods gave similar mean groundwater seepage rates into the stream (0.3-0.6 m/d) during two 3-4 day field campaigns despite an order of magnitude difference in stream discharge between the campaigns. At low flow, estimates of flow-weighted mean nitrate concentrations in groundwater discharge ([NO3-]FWM) and nitrate flux from groundwater to the stream decreased with increasing degree of channel influence and measurement scale, i.e., [NO3-]FWM was 654, 561, and 451 µM for point, blanket, and reach mass-balance sampling, respectively. At high flow the trend was reversed, likely because reach mass-balance captured inputs from shallow transient high-nitrate flow paths while point and blanket measurements did not. Point sampling may be better suited to estimating aquifer discharge of nitrate, while reach mass-balance reflects full nitrate inputs into the channel (which at high flow may be more than aquifer discharge due to transient flow paths, and at low flow may be less than aquifer discharge due to channel-based nitrate removal). Modeling dissolved N2 from streambed samples suggested (1) about half of groundwater nitrate was denitrified prior to discharge from the aquifer, and (2) both extent of denitrification and initial nitrate concentration in groundwater (700-1300 µM) were related to land use, suggesting these forms of streambed sampling for groundwater can reveal watershed spatial relations relevant to nitrate contamination and fate in the aquifer.

Observing hydrological processes: recent advancements in surface flow monitoring through image analysis

NASA Astrophysics Data System (ADS)

Tauro, Flavia; Grimaldi, Salvatore

2017-04-01

Recently, several efforts have been devoted to the design and development of innovative, and often unintended, approaches for the acquisition of hydrological data. Among such pioneering techniques, this presentation reports recent advancements towards the establishment of a novel noninvasive and potentially continuous methodology based on the acquisition and analysis of images for spatially distributed observations of the kinematics of surface waters. The approach aims at enabling rapid, affordable, and accurate surface flow monitoring of natural streams. Flow monitoring is an integral part of hydrological sciences and is essential for disaster risk reduction and the comprehension of natural phenomena. However, water processes are inherently complex to observe: they are characterized by multiscale and highly heterogeneous phenomena which have traditionally demanded sophisticated and costly measurement techniques. Challenges in the implementation of such techniques have also resulted in lack of hydrological data during extreme events, in difficult-to-access environments, and at high temporal resolution. By combining low-cost yet high-resolution images and several velocimetry algorithms, noninvasive flow monitoring has been successfully conducted at highly heterogeneous scales, spanning from rills to highly turbulent streams, and medium-scale rivers, with minimal supervision by external users. Noninvasive image data acquisition has also afforded observations in high flow conditions. Latest novelties towards continuous flow monitoring at the catchment scale have entailed the development of a remote gauge-cam station on the Tiber River and integration of flow monitoring through image analysis with unmanned aerial systems (UASs) technology. The gauge-cam station and the UAS platform both afford noninvasive image acquisition and calibration through an innovative laser-based setup. Compared to traditional point-based instrumentation, images allow for generating surface flow velocity maps which fully describe the kinematics of the velocity field in natural streams. Also, continuous observations provide a close picture of the evolving dynamics of natural water bodies. Despite such promising achievements, dealing with images also involves coping with adverse illumination, massive data handling and storage, and data-intensive computing. Most importantly, establishing a novel observational technique requires estimation of the uncertainty associated to measurements and thorough comparison to existing benchmark approaches. In this presentation, we provide answers to some of these issues and perspectives for future research.

Assessment of flow regime alterations over a spectrum of temporal scales using wavelet-based approaches

NASA Astrophysics Data System (ADS)

Wu, Fu-Chun; Chang, Ching-Fu; Shiau, Jenq-Tzong

2015-05-01

The full range of natural flow regime is essential for sustaining the riverine ecosystems and biodiversity, yet there are still limited tools available for assessment of flow regime alterations over a spectrum of temporal scales. Wavelet analysis has proven useful for detecting hydrologic alterations at multiple scales via the wavelet power spectrum (WPS) series. The existing approach based on the global WPS (GWPS) ratio tends to be dominated by the rare high-power flows so that alterations of the more frequent low-power flows are often underrepresented. We devise a new approach based on individual deviations between WPS (DWPS) that are root-mean-squared to yield the global DWPS (GDWPS). We test these two approaches on the three reaches of the Feitsui Reservoir system (Taiwan) that are subjected to different classes of anthropogenic interventions. The GDWPS reveal unique features that are not detected with the GWPS ratios. We also segregate the effects of individual subflow components on the overall flow regime alterations using the subflow GDWPS. The results show that the daily hydropeaking waves below the reservoir not only intensified the flow oscillations at daily scale but most significantly eliminated subweekly flow variability. Alterations of flow regime were most severe below the diversion weir, where the residual hydropeaking resulted in a maximum impact at daily scale while the postdiversion null flows led to large hydrologic alterations over submonthly scales. The smallest impacts below the confluence reveal that the hydrologic alterations at scales longer than 2 days were substantially mitigated with the joining of the unregulated tributary flows, whereas the daily-scale hydrologic alteration was retained because of the hydropeaking inherited from the reservoir releases. The proposed DWPS approach unravels for the first time the details of flow regime alterations at these intermediate scales that are overridden by the low-frequency high-power flows when the long-term averaged GWPS are used.

Highly Sensitive Hot-Wire Anemometry Based on Macro-Sized Double-Walled Carbon Nanotube Strands.

PubMed

Wang, Dingqu; Xiong, Wei; Zhou, Zhaoying; Zhu, Rong; Yang, Xing; Li, Weihua; Jiang, Yueyuan; Zhang, Yajun

2017-08-01

This paper presents a highly sensitive flow-rate sensor with carbon nanotubes (CNTs) as sensing elements. The sensor uses micro-size centimeters long double-walled CNT (DWCNT) strands as hot-wires to sense fluid velocity. In the theoretical analysis, the sensitivity of the sensor is demonstrated to be positively related to the ratio of its surface. We assemble the flow sensor by suspending the DWCNT strand directly on two tungsten prongs and dripping a small amount of silver glue onto each contact between the DWCNT and the prongs. The DWCNT exhibits a positive TCR of 1980 ppm/K. The self-heating effect on the DWCNT was observed while constant current was applied between the two prongs. This sensor can evidently respond to flow rate, and requires only several milliwatts to operate. We have, thus far, demonstrated that the CNT-based flow sensor has better sensitivity than the Pt-coated DWCNT sensor.

An experimental investigation of the flow physics of high-lift systems

NASA Technical Reports Server (NTRS)

Thomas, Flint O.; Nelson, R. C.

1995-01-01

This progress report is a series of overviews outlining experiments on the flow physics of confluent boundary layers for high-lift systems. The research objectives include establishing the role of confluent boundary layer flow physics in high-lift production; contrasting confluent boundary layer structures for optimum and non-optimum C(sub L) cases; forming a high quality, detailed archival data base for CFD/modelling; and examining the role of relaminarization and streamline curvature. Goals of this research include completing LDV study of an optimum C(sub L) case; performing detailed LDV confluent boundary layer surveys for multiple non-optimum C(sub L) cases; obtaining skin friction distributions for both optimum and non-optimum C(sub L) cases for scaling purposes; data analysis and inner and outer variable scaling; setting-up and performing relaminarization experiments; and a final report establishing the role of leading edge confluent boundary layer flow physics on high-lift performance.

Computed Flow Through An Artificial Heart Valve

NASA Technical Reports Server (NTRS)

Rogers, Stewart E.; Kwak, Dochan; Kiris, Cetin; Chang, I-Dee

1994-01-01

Report discusses computations of blood flow through prosthetic tilting disk valve. Computational procedure developed in simulation used to design better artificial hearts and valves by reducing or eliminating following adverse flow characteristics: large pressure losses, which prevent hearts from working efficiently; separated and secondary flows, which causes clotting; and high turbulent shear stresses, which damages red blood cells. Report reiterates and expands upon part of NASA technical memorandum "Computed Flow Through an Artificial Heart and Valve" (ARC-12983). Also based partly on research described in "Numerical Simulation of Flow Through an Artificial Heart" (ARC-12478).

Modified Beer-Lambert law for blood flow.

PubMed

Baker, Wesley B; Parthasarathy, Ashwin B; Busch, David R; Mesquita, Rickson C; Greenberg, Joel H; Yodh, A G

2014-11-01

We develop and validate a Modified Beer-Lambert law for blood flow based on diffuse correlation spectroscopy (DCS) measurements. The new formulation enables blood flow monitoring from temporal intensity autocorrelation function data taken at single or multiple delay-times. Consequentially, the speed of the optical blood flow measurement can be substantially increased. The scheme facilitates blood flow monitoring of highly scattering tissues in geometries wherein light propagation is diffusive or non-diffusive, and it is particularly well-suited for utilization with pressure measurement paradigms that employ differential flow signals to reduce contributions of superficial tissues.

Microfluidic Imaging Flow Cytometry by Asymmetric-detection Time-stretch Optical Microscopy (ATOM).

PubMed

Tang, Anson H L; Lai, Queenie T K; Chung, Bob M F; Lee, Kelvin C M; Mok, Aaron T Y; Yip, G K; Shum, Anderson H C; Wong, Kenneth K Y; Tsia, Kevin K

2017-06-28

Scaling the number of measurable parameters, which allows for multidimensional data analysis and thus higher-confidence statistical results, has been the main trend in the advanced development of flow cytometry. Notably, adding high-resolution imaging capabilities allows for the complex morphological analysis of cellular/sub-cellular structures. This is not possible with standard flow cytometers. However, it is valuable for advancing our knowledge of cellular functions and can benefit life science research, clinical diagnostics, and environmental monitoring. Incorporating imaging capabilities into flow cytometry compromises the assay throughput, primarily due to the limitations on speed and sensitivity in the camera technologies. To overcome this speed or throughput challenge facing imaging flow cytometry while preserving the image quality, asymmetric-detection time-stretch optical microscopy (ATOM) has been demonstrated to enable high-contrast, single-cell imaging with sub-cellular resolution, at an imaging throughput as high as 100,000 cells/s. Based on the imaging concept of conventional time-stretch imaging, which relies on all-optical image encoding and retrieval through the use of ultrafast broadband laser pulses, ATOM further advances imaging performance by enhancing the image contrast of unlabeled/unstained cells. This is achieved by accessing the phase-gradient information of the cells, which is spectrally encoded into single-shot broadband pulses. Hence, ATOM is particularly advantageous in high-throughput measurements of single-cell morphology and texture - information indicative of cell types, states, and even functions. Ultimately, this could become a powerful imaging flow cytometry platform for the biophysical phenotyping of cells, complementing the current state-of-the-art biochemical-marker-based cellular assay. This work describes a protocol to establish the key modules of an ATOM system (from optical frontend to data processing and visualization backend), as well as the workflow of imaging flow cytometry based on ATOM, using human cells and micro-algae as the examples.

Sensitivity of boundary-layer stability to base-state distortions at high Mach numbers

NASA Astrophysics Data System (ADS)

Park, Junho; Zaki, Tamer

2017-11-01

The stability diagram of high-speed boundary layers has been established by evaluating the linear instability modes of the similarity profile, over wide ranges of Reynolds and Mach numbers. In real flows, however, the base state can deviate from the similarity profile. Both the base velocity and temperature can be distorted, for example due to roughness and thermal wall treatments. We review the stability problem of high-speed boundary layer, and derive a new formulation of the sensitivity to base-state distortion using forward and adjoint parabolized stability equations. The new formulation provides qualitative and quantitative interpretations on change in growth rate due to modifications of mean-flow and mean-temperature in heated high-speed boundary layers, and establishes the foundation for future control strategies. This work has been funded by the Air Force Office of Scientific Research (AFOSR) Grant: FA9550-16-1-0103.

In vivo vascular flow profiling combined with optical tweezers based blood routing

NASA Astrophysics Data System (ADS)

Meissner, Robert; Sugden, Wade W.; Siekmann, Arndt F.; Denz, Cornelia

2017-07-01

In vivo wall shear rate is quantified during zebrafish development using particle image velocimetry for biomedical diagnosis and modeling of artificial vessels. By using brightfield microscopy based high speed video tracking we can resolve single heart-beat cycles of blood flow in both space and time. Maximum blood flow velocities and wall shear rates are presented for zebrafish at two and three days post fertilization. By applying biocompatible optical tweezers as an Optical rail we present rerouting of red blood cells in vivo. With purely light-driven means we are able to compensate the lack of proper red blood cell blood flow in so far unperfused capillaries.

Evaluation of Streamflow Requirements for Habitat Protection by Comparison to Streamflow Characteristics at Index Streamflow-Gaging Stations in Southern New England

USGS Publications Warehouse

Armstrong, David S.; Parker, Gene W.; Richards, Todd A.

2003-01-01

Streamflow characteristics and methods for determining streamflow requirements for habitat protection were investigated at 23 active index streamflow-gaging stations in southern New England. Fish communities sampled near index streamflow-gaging stations in Massachusetts have a high percentage of fish that require flowing-water habitats for some or all of their life cycle. The relatively unaltered flow condition at these sites was assumed to be one factor that has contributed to this condition. Monthly flow durations and low flow statistics were determined for the index streamflow-gaging stations for a 25- year period from 1976 to 2000. Annual hydrographs were prepared for each index station from median streamflows at the 50-percent monthly flow duration, normalized by drainage area. A median monthly flow of 1 ft3/s/mi2 was used to split hydrographs into a high-flow period (November–May), and a low-flow period (June–October). The hydrographs were used to classify index stations into groups with similar median monthly flow durations. Index stations were divided into four regional groups, roughly paralleling the coast, to characterize streamflows for November to May; and into two groups, on the basis of base-flow index and percentage of sand and gravel in the contributing area, for June to October. For the June to October period, for index stations with a high base-flow index and contributing areas greater than 20 percent sand and gravel, median streamflows at the 50-percent monthly flow duration, normalized by drainage area, were 0.57, 0.49, and 0.46 ft3/s/mi2 for July, August, and September, respectively. For index stations with a low base-flow index and contributing areas less than 20 percent sand and gravel, median streamflows at the 50-percent monthly flow duration, normalized by drainage area, were 0.34, 0.28, and 0.27 ft3/s/mi2 for July, August, and September, respectively. Streamflow variability between wet and dry years can be characterized by use of the interquartile range of median streamflows at selected monthly flow durations. For example, the median Q50 discharge for August had an interquartile range of 0.30 to 0.87 ft3/s/mi2 for the high-flow group and 0.16 to 0.47 ft3/s/mi2 for the low-flow group. Streamflow requirements for habitat protection were determined for 23 index stations by use of three methods based on hydrologic records, the Range of Variability Approach, the Tennant method, and the New England Aquatic-Base-Flow method. Normalized flow management targets determined by the Range of Variability Approach for July, August, and September ranged between 0.21 and 0.84 ft3/s/mi2 for the low monthly flow duration group, and 0.37 and 1.27 ft3/s/mi2 for the high monthly flow duration group. Median streamflow requirements for habitat protection during summer for the 23 index streamflow-gaging stations determined by the Tennant method, normalized by drainage area, were 0.81, 0.61, and 0.21 ft3/s/mi2 for the Tennant 40-, 30-, and 10-percent of the mean annual flow methods, representing good, fair, and poor stream habitat conditions in summer, according to Tennant. New England Aquatic-Base-Flow streamflow requirements for habitat protection during summer were determined from median of monthly mean flows for August for index streamflow-gaging stations having drainage areas greater than 50 mi2 . For five index streamflow-gaging stations in the low median monthly flow group, the average median monthly mean streamflow for August, normalized by drainage area, was 0.48 ft3/s/mi2. Streamflow requirements for habitat protection were determined for riffle habitats near 10 index stations by use of two methods based on hydraulic ratings, the Wetted-Perimeter and R2Cross methods. Hydraulic parameters required by these methods were simulated by calibrated HEC-RAS models. Wetted-Perimeter streamflow requirements for habitat protection, normalized by drainage area, ranged between 0.13 and 0.58 ft3/s/mi2, and had a median value of 0.37 ft3/s/mi2. Streamflow requirements determined by the R2Cross 3-of-3 criteria method ranged between 0.39 and 2.1 ft3/s/mi2 , and had a median of 0.84 ft3/s/mi2. Streamflow requirements determined by the R2Cross 2-of-3 criteria method, normalized by drainage area, ranged between 0.16 and 0.85 ft3/s/mi2 and had a median of 0.36 ft3/s/mi2 , respectively. Streamflow requirements determined by the different methods were evaluated by comparison to streamflow statistics from the index streamflow-gaging stations.

Systematic characterization of degas-driven flow for poly(dimethylsiloxane) microfluidic devices

DOE PAGES

Liang, David Y.; Tentori, Augusto M.; Dimov, Ivan K.; ...

2011-01-01

Degas-driven flow is a novel phenomenon used to propel fluids in poly(dimethylsiloxane) (PDMS)-based microfluidic devices without requiring any external power. This method takes advantage of the inherently high porosity and air solubility of PDMS by removing air molecules from the bulk PDMS before initiating the flow. The dynamics of degas-driven flow are dependent on the channel and device geometries and are highly sensitive to temporal parameters. These dependencies have not been fully characterized, hindering broad use of degas-driven flow as a microfluidic pumping mechanism. Here, we characterize, for the first time, the effect of various parameters on the dynamics ofmore » degas-driven flow, including channel geometry, PDMS thickness, PDMS exposure area, vacuum degassing time, and idle time at atmospheric pressure before loading. We investigate the effect of these parameters on flow velocity as well as channel fill time for the degas-driven flow process. Using our devices, we achieved reproducible flow with a standard deviation of less than 8% for flow velocity, as well as maximum flow rates of up to 3 nL/s and mean flow rates of approximately 1-1.5 nL/s. Parameters such as channel surface area and PDMS chip exposure area were found to have negligible impact on degas-driven flow dynamics, whereas channel cross-sectional area, degas time, PDMS thickness, and idle time were found to have a larger impact. In addition, we develop a physical model that can predict mean flow velocities within 6% of experimental values and can be used as a tool for future design of PDMS-based microfluidic devices that utilize degas-driven flow.« less

Performance of the active sidewall boundary-layer removal system for the Langley 0.3-meter Transonic Cryogenic Tunnel

NASA Technical Reports Server (NTRS)

Balakrishna, S.; Kilgore, W. Allen; Murthy, A. V.

1989-01-01

A performance evaluation of an active sidewall boundary-layer removal system for the Langley 0.3-m Transonic Cryogenic Tunnel (TCT) was evaluated in 1988. This system uses a compressor and two throttling digital valves to control the boundary-layer mass flow removal from the tunnel. The compressor operates near the maximum pressure ratio for all conditions. The system uses a surge prevention and flow recirculation scheme. A microprocessor based controller is used to provide the necessary mass flow and compressor pressure ratio control. Initial tests on the system indicated problems in realizing smooth mass flow control while running the compressor at high speed and high pressure ratios. An alternate method has been conceived to realize boundary-layer mass flow control which avoids the recirculation of the compressor mass flow and operation near the compressor surge point. This scheme is based on varying the speed of the compressor for a sufficient pressure ratio to provide needed mass flow removal. The system has a mass flow removal capability of about 10 percent of test section flow at M = 0.3 and 4 percent at M = 0.8. The system performance has been evaluated in the form of the compressor map, and compressor tunnel interface characteristics covering most of the 0.3-m TCT operational envelope.

Dynamic MRI for distinguishing high-flow from low-flow peripheral vascular malformations.

PubMed

Ohgiya, Yoshimitsu; Hashimoto, Toshi; Gokan, Takehiko; Watanabe, Shouji; Kuroda, Masayoshi; Hirose, Masanori; Matsui, Seishi; Nobusawa, Hiroshi; Kitanosono, Takashi; Munechika, Hirotsugu

2005-11-01

The purpose of our study was to assess the usefulness of dynamic MRI in distinguishing high-flow vascular malformations from low-flow vascular malformations, which do not need angiography for treatment. Between September 2001 and January 2003, 16 patients who underwent conventional and dynamic MRI had peripheral vascular malformations (six high- and 10 low-flow). The temporal resolution of dynamic MRI was 5 sec. Time intervals between beginning of enhancement of an arterial branch in the vicinity of a lesion in the same slice and the onset of enhancement in the lesion were calculated. We defined these time intervals as "artery-lesion enhancement time." Time intervals between the onset of enhancement in the lesion and the time of the maximal percentage of enhancement above baseline of the lesion within 120 sec were measured. We defined these time intervals as "contrast rise time" of the lesion. Diagnosis of the peripheral vascular malformations was based on angiographic or venographic findings. The mean artery-lesion enhancement time of the high-flow vascular malformations (3.3 sec [range, 0-5 sec]) was significantly shorter than that of the low-flow vascular malformations (8.8 sec [range, 0-20 sec]) (Mann-Whitney test, p < 0.05). The mean maximal lesion enhancement time of the high-flow vascular malformations (5.8 sec [range, 5-10 sec]) was significantly shorter than that of the low-flow vascular malformations (88.4 sec [range, 50-100 sec]) (Mann-Whitney test, p < 0.01). Dynamic MRI is useful for distinguishing high-flow from low-flow vascular malformations, especially when the contrast rise time of the lesion is measured.

Thermal Flow Sensors for Harsh Environments.

PubMed

Balakrishnan, Vivekananthan; Phan, Hoang-Phuong; Dinh, Toan; Dao, Dzung Viet; Nguyen, Nam-Trung

2017-09-08

Flow sensing in hostile environments is of increasing interest for applications in the automotive, aerospace, and chemical and resource industries. There are thermal and non-thermal approaches for high-temperature flow measurement. Compared to their non-thermal counterparts, thermal flow sensors have recently attracted a great deal of interest due to the ease of fabrication, lack of moving parts and higher sensitivity. In recent years, various thermal flow sensors have been developed to operate at temperatures above 500 °C. Microelectronic technologies such as silicon-on-insulator (SOI), and complementary metal-oxide semiconductor (CMOS) have been used to make thermal flow sensors. Thermal sensors with various heating and sensing materials such as metals, semiconductors, polymers and ceramics can be selected according to the targeted working temperature. The performance of these thermal flow sensors is evaluated based on parameters such as thermal response time, flow sensitivity. The data from thermal flow sensors reviewed in this paper indicate that the sensing principle is suitable for the operation under harsh environments. Finally, the paper discusses the packaging of the sensor, which is the most important aspect of any high-temperature sensing application. Other than the conventional wire-bonding, various novel packaging techniques have been developed for high-temperature application.

Thermal Flow Sensors for Harsh Environments

PubMed Central

Dinh, Toan; Dao, Dzung Viet

2017-01-01

Flow sensing in hostile environments is of increasing interest for applications in the automotive, aerospace, and chemical and resource industries. There are thermal and non-thermal approaches for high-temperature flow measurement. Compared to their non-thermal counterparts, thermal flow sensors have recently attracted a great deal of interest due to the ease of fabrication, lack of moving parts and higher sensitivity. In recent years, various thermal flow sensors have been developed to operate at temperatures above 500 °C. Microelectronic technologies such as silicon-on-insulator (SOI), and complementary metal-oxide semiconductor (CMOS) have been used to make thermal flow sensors. Thermal sensors with various heating and sensing materials such as metals, semiconductors, polymers and ceramics can be selected according to the targeted working temperature. The performance of these thermal flow sensors is evaluated based on parameters such as thermal response time, flow sensitivity. The data from thermal flow sensors reviewed in this paper indicate that the sensing principle is suitable for the operation under harsh environments. Finally, the paper discusses the packaging of the sensor, which is the most important aspect of any high-temperature sensing application. Other than the conventional wire-bonding, various novel packaging techniques have been developed for high-temperature application. PMID:28885595

Cross-flow shearing effects on the trajectory of highly buoyant bent-over plumes

NASA Astrophysics Data System (ADS)

Tohidi, Ali; Kaye, Nigel Berkeley; Gollner, Michael J.

2017-11-01

The dynamics of highly buoyant plumes in cross-flow is ubiquitous throughout both industrial and environmental phenomena. The rise of smoke from a chimney, wastewater discharge into river currents, and dispersion of wildfire plumes are only a few instances. There have been many previous studies investigating the behavior of jets and highly buoyant plumes in cross-flow. So far, however, very little attention has been paid to the role of shearing effects in the boundary layer on the plume trajectory, particularly on the rise height. Numerical simulations and dimensional analysis are conducted to characterize the near- and far-field behavior of a highly buoyant plume in a boundary layer cross-flow. The results show that shear in the cross-flow leads to large differences in the rise height of the plume in relation to a uniform cross-flow, especially at far-field. This material is based upon work supported by the National Science Foundation under Grant No.1200560. Any opinions, findings, and conclusions or recommendations expressed in the material are of the authors and do not necessarily reflect the views of NSF.

A study of high speed flows in an aircraft transition duct. Ph.D. Thesis - Iowa State Univ.

NASA Technical Reports Server (NTRS)

Reichert, Bruce A.

1991-01-01

The study of circular-to-rectangular transition duct flows with and without inlet swirl is presented. A method was devised to create a swirling, solid body rotational flow with minimal associated disturbances. Details of the swirl generator design and construction are discussed. Coefficients based on velocities and total and static pressures measured in cross stream planes at four axial locations within the transition duct along with surface static pressures and surface oil film visualization are presented for both nonswirling and swirling incoming flows. A method was developed to acquire trace gas measurements within the transition duct at high flow velocities. Statistical methods are used to help interpret the trace gas results.

Investigations on the Aerodynamic Characteristics and Blade Excitations of the Radial Turbine with Pulsating Inlet Flow

NASA Astrophysics Data System (ADS)

Liu, Yixiong; Yang, Ce; Yang, Dengfeng; Zhang, Rui

2016-04-01

The aerodynamic performance, detailed unsteady flow and time-based excitations acting on blade surfaces of a radial flow turbine have been investigated with pulsation flow condition. The results show that the turbine instantaneous performance under pulsation flow condition deviates from the quasi-steady value significantly and forms obvious hysteretic loops around the quasi-steady conditions. The detailed analysis of unsteady flow shows that the characteristic of pulsation flow field in radial turbine is highly influenced by the pulsation inlet condition. The blade torque, power and loading fluctuate with the inlet pulsation wave in a pulse period. For the blade excitations, the maximum and the minimum blade excitations conform to the wave crest and wave trough of the inlet pulsation, respectively, in time-based scale. And toward blade chord direction, the maximum loading distributes along the blade leading edge until 20% chord position and decreases from the leading to trailing edge.

Radical Compatibility with Nonaqueous Electrolytes and Its Impact on an All-Organic Redox Flow Battery.

PubMed

Wei, Xiaoliang; Xu, Wu; Huang, Jinhua; Zhang, Lu; Walter, Eric; Lawrence, Chad; Vijayakumar, M; Henderson, Wesley A; Liu, Tianbiao; Cosimbescu, Lelia; Li, Bin; Sprenkle, Vincent; Wang, Wei

2015-07-20

Nonaqueous redox flow batteries hold the promise of achieving higher energy density because of the broader voltage window than aqueous systems, but their current performance is limited by low redox material concentration, cell efficiency, cycling stability, and current density. We report a new nonaqueous all-organic flow battery based on high concentrations of redox materials, which shows significant, comprehensive improvement in flow battery performance. A mechanistic electron spin resonance study reveals that the choice of supporting electrolytes greatly affects the chemical stability of the charged radical species especially the negative side radical anion, which dominates the cycling stability of these flow cells. This finding not only increases our fundamental understanding of performance degradation in flow batteries using radical-based redox species, but also offers insights toward rational electrolyte optimization for improving the cycling stability of these flow batteries. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Historical changes in annual peak flows in Maine and implications for flood-frequency analyses

USGS Publications Warehouse

Hodgkins, Glenn A.

2010-01-01

Flood-frequency analyses use statistical methods to compute peak streamflows for selected recurrence intervals— the average number of years between peak flows that are equal to or greater than a specified peak flow. Analyses are based on annual peak flows at a stream. It has long been assumed that the annual peak streamflows used in these computations were stationary (non-changing) over very long periods of time, except in river basins subject to direct effects of human activities, such as urbanization and regulation. Because of the potential effects of global warming on peak flows, the assumption of peak-flow stationarity has recently been questioned. Maine has many streamgages with 50 to 105 years of recorded annual peak streamflows. In this study, this long-term record has been tested for historical flood-frequency stationarity, to provide some insight into future flood frequency. Changes over time in annual instantaneous peak streamflows at 28 U.S. Geological Survey streamgages with long-term data (50 or more years) and relatively complete records were investigated by examining linear trends for each streamgage’s period of record. None of the 28 streamgages had more than 5 years of missing data. Eight streamgages have substantial streamflow regulation. Because previous studies have suggested that changes over time may have occurred as a step change around 1970, step changes between each streamgage’s older record (start year to 1970) and newer record (1971 to 2006) also were computed. The median change over time for all 28 streamgages is an increase of 15.9 percent based on a linear change and an increase of 12.4 percent based on a step change. The median change for the 20 unregulated streamgages is slightly higher than for all 28 streamgages; it is 18.4 percent based on a linear change and 15.0 percent based on a step change. Peak flows with 100- and 5-year recurrence intervals were computed for the 28 streamgages using the full annual peak-flow record and multiple sub-periods of that record using the guidelines (Bulletin 17B) of the Interagency Advisory Committee on Water Data. Magnitudes of 100- and 5-year peak flows computed from sub-periods then were compared to those computed from the full period. Sub-periods of 30 years with starting years staggered by 10 years were evaluated (1907–36, 1917–46, 1927–56, 1937–66, 1947–76, 1957–86, 1967–96, and 1977–2006). Two other sub-periods were evaluated using older data (start-of-record to 1970) and newer data (1971 to 2006). The 5-year peak flow is used to represent small and relatively frequent flood flows in Maine, whereas the 100-year peak flow is used to represent large flood flows. The 1967–96 sub-period generated the highest 100- and 5-year peak flows overall when compared to peak flows based on the full period of record; the median difference for all 28 streamgages is 8 percent for 100- and 5-year peak flows. The 1977–2006 and 1971–2006 sub-periods also generated 100- and 5-year peak flows higher than peak flows based on the full period of record, but not as high as the peak flows based on the 1967–96 sub-period. The 1937–66 sub-period generated the lowest 100- and 5-year peak flows overall. The median difference from full-period peak flows is -11 percent for 100-year peak flows and -8 percent for 5-year peak flows. Overall, differences between peak flows based on the sub-periods and those based on the full periods, generated using the 20 unregulated streamgages, are similar to differences using all 28 streamgages. Increases in the 5- and 100-year peak flows based on recent years of record are, in general, modest when compared to peak flows based on complete periods of record. The highest peak flows are based on the 1967–96 sub-period rather than the most recent sub-period (1977-2006). Peak flows for selected recurrence intervals are sensitive to very high peak flows that may occur once in a century or even less frequently. It is difficult, therefore, to determine which approach will produce the most reliable future estimates of peak flows for selected recurrence intervals, using only recent years of record or the traditional method using the entire historical period. One possible conservative approach to computing peak flows of selected recurrence intervals would be to compute peak flows using recent annual peak flows and the entire period of record, then choose the higher computed value. Whether recent or entire periods of record are used to compute peak flows of selected recurrence intervals, the results of this study highlight the importance of using recent data in the computation of the peak flows. The use of older records alone could result in underestimation of peak flows, particularly peak flows with short recurrence intervals, such as the 5-year peak flows.

Evaluation of geophysical mass flow models using the 2006 block-and-ash flows of Merapi Volcano, Java, Indonesia: Towards a short-term hazard assessment tool

NASA Astrophysics Data System (ADS)

Charbonnier, S. J.; Gertisser, R.

2012-06-01

The dynamics and depositional processes associated with block-and-ash flows (BAFs) are most commonly inferred to be a function of granular or inertial grain flow, similar to debris flows and cold rock avalanches. Existing geophysical mass flow models are either based on frictional (Mohr-Coulomb) behavior (the Titan2D model developed at the State University of New York at Buffalo, USA) or another rheological law (i.e., a constant retarding stress), eventually adding some viscous and turbulent components (the VolcFlow model developed at the Laboratoire Magmas et Volcans, Clermont-Ferrand, France). The 2006 BAFs of Merapi present a rare opportunity to test these two well-established models against a well-constrained field example. Integration of high-resolution field-based data into numerical simulations allows the validity of these models to be tested and rapid quantification of best-fit input parameters. We first show that with the incorporation of spatially varying bed friction angles, Titan2D is capable of reproducing the paths, runout distances, areas covered and deposited volumes of the 2006 Merapi flows over highly complex topography. However, some discrepancies with field data are noted and the velocity and travel time of the flows do not match entirely. Using a single free parameter (a constant retarding stress), simulations obtained with the VolcFlow model also reproduce the morphology and distribution of the natural deposits as well as the time of emplacement and velocities of the flows. The results suggest that the performance of these models in simulating actual events is critically dependent on: (1) the calibration of the model by using extensive field-based data such as deposit distribution, and processes of flow generation, transport and deposition; (2) the incorporation of a suitable numerical topographic dataset (i.e., high-resolution digital elevation model), and (3) the choice of input parameters, such as location and volume of the initial pile of material and source characteristics (single or multiple dome-collapse, dome-collapse duration and total volume of collapsed material). Sensitivity analyses and inundation maps based on the probability of impact were used to produce a suite of potentially inundated areas from future gravitational dome-collapse events affecting the Gendol valley and adjacent areas on the southern flank of the volcano. Our results provide the basis for defining hazard zonations of key areas at risk from BAFs which will be generated during future comparable eruptions at Merapi.

Investigation of wood combustion in the high-enthalpy oxidizer flow

NASA Astrophysics Data System (ADS)

Reshetnikov, S. M.; Zyryanov, I. A.; Budin, A. G.; Pozolotin, A. P.

2017-01-01

The experimental data of wood combustion in the high-enthalpy oxidizer flowresearch is presented. Combustion laws of two wood species (pine and birch) in a hybrid rocket engine (HRE) are obtained. Heat flows from the flame to the condensed phase surface are defined. The prospects of the wood use in the HRE (based on thrust characteristics) are shown.

Modeling highly transient flow, mass, and heat transport in the Chattahoochee River near Atlanta, Georgia

USGS Publications Warehouse

Jobson, Harvey E.; Keefer, Thomas N.

1979-01-01

A coupled flow-temperature model has been developed and verified for a 27.9-km reach of the Chattahoochee River between Buford Dam and Norcross, Ga. Flow in this reach of the Chattahoochee is continuous but highly regulated by Buford Dam, a flood-control and hydroelectric facility located near Buford, Ga. Calibration and verification utilized two sets of data collected under highly unsteady discharge conditions. Existing solution techniques, with certain minor improvements, were applied to verify the existing technology of flow and transport modeling. A linear, implicit finite-difference flow model was coupled with implicit, finite-difference transport and temperature models. Both the conservative and nonconservative forms of the transport equation were solved, and the difference in the predicted concentrations of dye were found to be insignificant. The temperature model, therefore, was based on the simpler nonconservative form of the transport equation. (Woodard-USGS)

Unsteady Computational Tests of a Non-Equilibrium

NASA Astrophysics Data System (ADS)

Jirasek, Adam; Hamlington, Peter; Lofthouse, Andrew; Usafa Collaboration; Cu Boulder Collaboration

2017-11-01

A non-equilibrium turbulence model is assessed on simulations of three practically-relevant unsteady test cases; oscillating channel flow, transonic flow around an oscillating airfoil, and transonic flow around the Benchmark Super-Critical Wing. The first case is related to piston-driven flows while the remaining cases are relevant to unsteady aerodynamics at high angles of attack and transonic speeds. Non-equilibrium turbulence effects arise in each of these cases in the form of a lag between the mean strain rate and Reynolds stresses, resulting in reduced kinetic energy production compared to classical equilibrium turbulence models that are based on the gradient transport (or Boussinesq) hypothesis. As a result of the improved representation of unsteady flow effects, the non-equilibrium model provides substantially better agreement with available experimental data than do classical equilibrium turbulence models. This suggests that the non-equilibrium model may be ideally suited for simulations of modern high-speed, high angle of attack aerodynamics problems.

Ambipolar zinc-polyiodide electrolyte for a high-energy density aqueous redox flow battery

PubMed Central

Li, Bin; Nie, Zimin; Vijayakumar, M.; Li, Guosheng; Liu, Jun; Sprenkle, Vincent; Wang, Wei

2015-01-01

Redox flow batteries are receiving wide attention for electrochemical energy storage due to their unique architecture and advantages, but progress has so far been limited by their low energy density (~25 Wh l−1). Here we report a high-energy density aqueous zinc-polyiodide flow battery. Using the highly soluble iodide/triiodide redox couple, a discharge energy density of 167 Wh l−1 is demonstrated with a near-neutral 5.0 M ZnI2 electrolyte. Nuclear magnetic resonance study and density functional theory-based simulation along with flow test data indicate that the addition of an alcohol (ethanol) induces ligand formation between oxygen on the hydroxyl group and the zinc ions, which expands the stable electrolyte temperature window to from −20 to 50 °C, while ameliorating the zinc dendrite. With the high-energy density and its benign nature free from strong acids and corrosive components, zinc-polyiodide flow battery is a promising candidate for various energy storage applications. PMID:25709083

Ambipolar zinc-polyiodide electrolyte for a high-energy density aqueous redox flow battery.

PubMed

Li, Bin; Nie, Zimin; Vijayakumar, M; Li, Guosheng; Liu, Jun; Sprenkle, Vincent; Wang, Wei

2015-02-24

Redox flow batteries are receiving wide attention for electrochemical energy storage due to their unique architecture and advantages, but progress has so far been limited by their low energy density (~25 Wh l(-1)). Here we report a high-energy density aqueous zinc-polyiodide flow battery. Using the highly soluble iodide/triiodide redox couple, a discharge energy density of 167 Wh l(-1) is demonstrated with a near-neutral 5.0 M ZnI2 electrolyte. Nuclear magnetic resonance study and density functional theory-based simulation along with flow test data indicate that the addition of an alcohol (ethanol) induces ligand formation between oxygen on the hydroxyl group and the zinc ions, which expands the stable electrolyte temperature window to from -20 to 50 °C, while ameliorating the zinc dendrite. With the high-energy density and its benign nature free from strong acids and corrosive components, zinc-polyiodide flow battery is a promising candidate for various energy storage applications.

Comparison of standard- and nano-flow liquid chromatography platforms for MRM-based quantitation of putative plasma biomarker proteins.

PubMed

Percy, Andrew J; Chambers, Andrew G; Yang, Juncong; Domanski, Dominik; Borchers, Christoph H

2012-09-01

The analytical performance of a standard-flow ultra-high-performance liquid chromatography (UHPLC) and a nano-flow high-performance liquid chromatography (HPLC) system, interfaced to the same state-of-the-art triple-quadrupole mass spectrometer, were compared for the multiple reaction monitoring (MRM)-mass spectrometry (MS)-based quantitation of a panel of 48 high-to-moderate-abundance cardiovascular disease-related plasma proteins. After optimization of the MRM transitions for sensitivity and testing for chemical interference, the optimum sensitivity, loading capacity, gradient, and retention-time reproducibilities were determined. We previously demonstrated the increased robustness of the standard-flow platform, but we expected that the standard-flow platform would have an overall lower sensitivity. This study was designed to determine if this decreased sensitivity could be compensated for by increased sample loading. Significantly fewer interferences with the MRM transitions were found for the standard-flow platform than for the nano-flow platform (2 out of 103 transitions compared with 42 out of 103 transitions, respectively), which demonstrates the importance of interference-testing when nano-flow systems are used. Using only interference-free transitions, 36 replicate LC/MRM-MS analyses resulted in equal signal reproducibilities between the two platforms (9.3 % coefficient of variation (CV) for 88 peptide targets), with superior retention-time precision for the standard-flow platform (0.13 vs. 6.1 % CV). Surprisingly, for 41 of the 81 proteotypic peptides in the final assay, the standard-flow platform was more sensitive while for 9 of 81 the nano-flow platform was more sensitive. For these 81 peptides, there was a good correlation between the two sets of results (R(2) = 0.98, slope = 0.97). Overall, the standard-flow platform had superior performance metrics for most peptides, and is a good choice if sufficient sample is available.

Analog laboratory experiments on the influence of substrate roughness on the run out distance of pyroclastic flows

NASA Astrophysics Data System (ADS)

Roche, O.; Chedevile, C.

2012-12-01

We carried out scaled experiments on gas-particles flows propagating on a rough substrate in order to investigate the emplacement of pyroclastic flows. The flows were generated from the release of non-fluidized or gas-fluidized columns of fine (80 μm) glass beads of height of 30 cm into a 3 m-long horizontal channel. The base of the channel was either smooth or was made rough by gluing a monodisperse layer of spherical particles of diameter of 80 μm to 3 mm. We defined the substrate roughness as the size of the glued particles, which corresponded to up to several tens of centimeters when scaled to the natural system. The flow front kinematics and the detailed interactions between the base of the flow and the rough substrate were investigated from high speed videos. We measured systematically the run out distance of the flows, and experiments were repeated 8-10 times for each configuration to obtain a mean value. The run out distance increased with the substrate roughness for both initially non-fluidized and fluidized flows. The run out had a minimum value for a smooth base and was about twice that value for the highest roughness of 3 mm. Analysis of the flow kinematics revealed that the increase in run out was caused by higher front velocities essentially at late stages of emplacement, during which the head of the flows stretched considerably. High speed videos made at the base of the flows showed that their head first slid over the substrate before aggregates of particles fell into the interstices between the particles forming the rough substrate, at a mean speed of several centimeters per second. In contrast, complementary experiments on flows of coarse beads of 350 μm showed that the substrate roughness did not influence their run out, and at the flow base their particles bumped into those of the substrate before falling individually into the interstices. These observations suggest that the positive correlation between the flow run out and the substrate roughness for flows of fine particles could result from two mechanisms. The first was the reduction of the contact area between the flow base and the substrate as the roughness increased because of the reduced number of particles per unit length. The second, main mechanism was auto-fluidization generated as the fine particles falling into the interstices expulsed the air upward at a velocity much larger than the minimum fluidization velocity. This promoted at least partial fluidization or additional pore pressure in case of initially non-fluidized or fluidized flows, respectively. This experimental investigation provides some counterintuitive results and has implication for hazards assessment. Other things being equal, the run out distance of fines-rich pyroclastic flows is expected to increase with the roughness of the terrain on which they propagate.

Extension of sonic anemometry to high subsonic Mach number flows

NASA Astrophysics Data System (ADS)

Otero, R.; Lowe, K. T.; Ng, W. F.

2017-03-01

In the literature, the application of sonic anemometry has been limited to low subsonic Mach number, near-incompressible flow conditions. To the best of the authors’ knowledge, this paper represents the first time a sonic anemometry approach has been used to characterize flow velocity beyond Mach 0.3. Using a high speed jet, flow velocity was measured using a modified sonic anemometry technique in flow conditions up to Mach 0.83. A numerical study was conducted to identify the effects of microphone placement on the accuracy of the measured velocity. Based on estimated error strictly due to uncertainty in time-of-acoustic flight, a random error of +/- 4 m s-1 was identified for the configuration used in this experiment. Comparison with measurements from a Pitot probe indicated a velocity RMS error of +/- 9 m s-1. The discrepancy in error is attributed to a systematic error which may be calibrated out in future work. Overall, the experimental results from this preliminary study support the use of acoustics for high subsonic flow characterization.

Characteristics of ion flow in the quiet state of the inner plasma sheet

NASA Technical Reports Server (NTRS)

Angelopoulos, V.; Kennel, C. F.; Coroniti, F. V.; Pellat, R.; Spence, H. E.; Kivelson, M. G.; Walker, R. J.; Baumjohann, W.; Feldman, W. C.; Gosling, J. T.

1993-01-01

We use AMPTE/IRM and ISEE 2 data to study the properties of the high beta plasma sheet, the inner plasma sheet (IPS). Bursty bulk flows (BBFs) are excised from the two databases, and the average flow pattern in the non-BBF (quiet) IPS is constructed. At local midnight this ensemble-average flow is predominantly duskward; closer to the flanks it is mostly earthward. The flow pattern agrees qualitatively with calculations based on the Tsyganenko (1987) model (T87), where the earthward flow is due to the ensemble-average cross tail electric field and the duskward flow is the diamagnetic drift due to an inward pressure gradient. The IPS is on the average in pressure equilibrium with the lobes. Because of its large variance the average flow does not represent the instantaneous flow field. Case studies also show that the non-BBF flow is highly irregular and inherently unsteady, a reason why earthward convection can avoid a pressure balance inconsistency with the lobes. The ensemble distribution of velocities is a fundamental observable of the quiet plasma sheet flow field.

Dynamics of Active Separation Control at High Reynolds Numbers

NASA Technical Reports Server (NTRS)

Pack, LaTunia G.; Seifert, Avi

2000-01-01

A series of active flow control experiments were recently conducted at high Reynolds numbers on a generic separated configuration. The model simulates the upper surface of a 20% thick Glauert-Goldschmied type airfoil at zero angle of attack. The flow is fully turbulent since the tunnel sidewall boundary layer flows over the model. The main motivation for the experiments is to generate a comprehensive data base for validation of unsteady numerical simulation as a first step in the development of a CFD design tool, without which it would not be possible to effectively utilize the great potential of unsteady flow control. This paper focuses on the dynamics of several key features of the baseline as well as the controlled flow. It was found that the thickness of the upstream boundary layer has a negligible effect on the flow dynamics. It is speculated that separation is caused mainly by the highly convex surface while viscous effects are less important. The two-dimensional separated flow contains unsteady waves centered on a reduced frequency of 0.9, while in the three dimensional separated flow, frequencies around a reduced frequency of 0.3 and 1 are active. Several scenarios of resonant wave interaction take place at the separated shear-layer and in the pressure recovery region. The unstable reduced frequency bands for periodic excitation are centered on 1.5 and 5, but these reduced frequencies are based on the length of the baseline bubble that shortens due to the excitation. The conventional works well for the coherent wave features. Reproduction of these dynamic effects by a numerical simulation would provide benchmark validation.

Design and Characterization of a Novel Bio-inspired Hair Flow Sensor Based on Resonant Sensing

NASA Astrophysics Data System (ADS)

Guo, X.; Yang, B.; Wang, Q. H.; Lu, C. F.; Hu, D.

2018-03-01

Flow sensors inspired by the natural hair sensing mechanism have great prospect in the research of micro-autonomous system and technology (MAST) for the three-dimensional structure characteristics with high spatial and quality utilization. A novel bio-inspired hair flow sensor (BHFS) based on resonant sensing with a unique asymmetric design is presented in this paper. A hair transducer and a signal detector which is constituted of a two-stage micro-leverage mechanism and two symmetrical resonators (double ended tuning fork, DETF) are adopted to realize the high sensitivity to air flow. The sensitivity of the proposed BHFS is improved significantly than the published ones due to the high sensitivity of resonators and the higher amplification factor possessed by the two-stage micro-leverage mechanism. The standard deep dry silicon on glass (DDSOG) process is chosen to fabricate the proposed BHFS. The experiment result demonstrates that the fabricated BHFS has a mechanical sensitivity of 5.26 Hz/(m/s)2 at a resonant frequency of 22 kHz with the hair height of 6 mm.

Reconstruction and analysis of the past five centuries of streamflow on northern slopes on Tianshan Mountains in Northern Xinjiang, China

NASA Astrophysics Data System (ADS)

Yang, Yuhui; Chen, Yaning; Wang, Minzhong; Sun, Huilan

2017-07-01

We examined the changes in streamflow on the northern slopes of the Tianshan Mountains in northern Xinjiang, China, over two time scales: the past 500 years, based on dendrochronology data; and the past 50 years, based on streamflow data from hydrological stations. The method of artificial neural networks built from the data of the 50-year period was used to reconstruct the streamflow of the 500-year period. The results indicate that streamflow has undergone seven high-flow periods and four low-flow periods during the past 500 years. To identify possible transition points in the streamflow, we applied the Mann-Kendall and running T tests to the 50- and 500-year periods, respectively. During the past 500 years, streamflow has changed significantly from low to high flow about three to four times, and from high to low flow about three to five times. Over the recent 50 years, there have been three phases of variation in river runoff, and the most distinct transition of streamflow occurred in 1996.

Exact docking flight controller for autonomous aerial refueling with back-stepping based high order sliding mode

NASA Astrophysics Data System (ADS)

Su, Zikang; Wang, Honglun; Li, Na; Yu, Yue; Wu, Jianfa

2018-02-01

Autonomous aerial refueling (AAR) exact docking control has always been an intractable problem due to the strong nonlinearity, the tight coupling of the 6 DOF aircraft model and the complex disturbances of the multiple environment flows. In this paper, the strongly coupled nonlinear 6 DOF model of the receiver aircraft which considers the multiple flow disturbances is established in the affine nonlinear form to facilitate the nonlinear controller design. The items reflecting the influence of the unknown flow disturbances in the receiver dynamics are taken as the components of the "lumped disturbances" together with the items which have no linear correlation with the virtual control variables. These unmeasurable lumped disturbances are estimated and compensated by a specially designed high order sliding mode observer (HOSMO) with excellent estimation property. With the compensation of the estimated lumped disturbances, a back-stepping high order sliding mode based exact docking flight controller is proposed for AAR in the presence of multiple flow disturbances. Extensive simulation results demonstrate the feasibility and superiority of the proposed docking controller.

New Developments of Computational Fluid Dynamics and Their Applications to Practical Engineering Problems

NASA Astrophysics Data System (ADS)

Chen, Hudong

2001-06-01

There have been considerable advances in Lattice Boltzmann (LB) based methods in the last decade. By now, the fundamental concept of using the approach as an alternative tool for computational fluid dynamics (CFD) has been substantially appreciated and validated in mainstream scientific research and in industrial engineering communities. Lattice Boltzmann based methods possess several major advantages: a) less numerical dissipation due to the linear Lagrange type advection operator in the Boltzmann equation; b) local dynamic interactions suitable for highly parallel processing; c) physical handling of boundary conditions for complicated geometries and accurate control of fluxes; d) microscopically consistent modeling of thermodynamics and of interface properties in complex multiphase flows. It provides a great opportunity to apply the method to practical engineering problems encountered in a wide range of industries from automotive, aerospace to chemical, biomedical, petroleum, nuclear, and others. One of the key challenges is to extend the applicability of this alternative approach to regimes of highly turbulent flows commonly encountered in practical engineering situations involving high Reynolds numbers. Over the past ten years, significant efforts have been made on this front at Exa Corporation in developing a lattice Boltzmann based commercial CFD software, PowerFLOW. It has become a useful computational tool for the simulation of turbulent aerodynamics in practical engineering problems involving extremely complex geometries and flow situations, such as in new automotive vehicle designs world wide. In this talk, we present an overall LB based algorithm concept along with certain key extensions in order to accurately handle turbulent flows involving extremely complex geometries. To demonstrate the accuracy of turbulent flow simulations, we provide a set of validation results for some well known academic benchmarks. These include straight channels, backward-facing steps, flows over a curved hill and typical NACA airfoils at various angles of attack including prediction of stall angle. We further provide numerous engineering cases, ranging from external aerodynamics around various car bodies to internal flows involved in various industrial devices. We conclude with a discussion of certain future extensions for complex fluids.

A new contrast-assisted method in microcirculation volumetric flow assessment

NASA Astrophysics Data System (ADS)

Lu, Sheng-Yi; Chen, Yung-Sheng; Yeh, Chih-Kuang

2007-03-01

Microcirculation volumetric flow rate is a significant index in diseases diagnosis and treatment such as diabetes and cancer. In this study, we propose an integrated algorithm to assess microcirculation volumetric flow rate including estimation of blood perfused area and corresponding flow velocity maps based on high frequency destruction/contrast replenishment imaging technique. The perfused area indicates the blood flow regions including capillaries, arterioles and venules. Due to the echo variance changes between ultrasonic contrast agents (UCAs) pre- and post-destruction two images, the perfused area can be estimated by the correlation-based approach. The flow velocity distribution within the perfused area can be estimated by refilling time-intensity curves (TICs) after UCAs destruction. Most studies introduced the rising exponential model proposed by Wei (1998) to fit the TICs. Nevertheless, we found the TICs profile has a great resemblance to sigmoid function in simulations and in vitro experiments results. Good fitting correlation reveals that sigmoid model was more close to actual fact in describing destruction/contrast replenishment phenomenon. We derived that the saddle point of sigmoid model is proportional to blood flow velocity. A strong linear relationship (R = 0.97) between the actual flow velocities (0.4-2.1 mm/s) and the estimated saddle constants was found in M-mode and B-mode flow phantom experiments. Potential applications of this technique include high-resolution volumetric flow rate assessment in small animal tumor and the evaluation of superficial vasculature in clinical studies.

Flow stabilization with active hydrodynamic cloaks.

PubMed

Urzhumov, Yaroslav A; Smith, David R

2012-11-01

We demonstrate that fluid flow cloaking solutions, based on active hydrodynamic metamaterials, exist for two-dimensional flows past a cylinder in a wide range of Reynolds numbers (Re's), up to approximately 200. Within the framework of the classical Brinkman equation for homogenized porous flow, we demonstrate using two different methods that such cloaked flows can be dynamically stable for Re's in the range of 5-119. The first highly efficient method is based on a linearization of the Brinkman-Navier-Stokes equation and finding the eigenfrequencies of the least stable eigenperturbations; the second method is a direct numerical integration in the time domain. We show that, by suppressing the von Kármán vortex street in the weakly turbulent wake, porous flow cloaks can raise the critical Reynolds number up to about 120 or five times greater than for a bare uncloaked cylinder.

Hydrological control over stream nitrate loss in an aggrading New Hampshire forest

NASA Astrophysics Data System (ADS)

Daley, R.; Goodale, C. L.; Buso, D.; Driscoll, C. T.; Fuss, C.; Likens, G. E.

2008-12-01

Stream chemistry of a small watershed in the Hubbard Brook Experimental Forest (Watershed 4) displays higher nitrate export than expected for an early successional forest in this region. Within Watershed 4, a small tributary (300 m in length) has a chemical signature far different from the main channel (1000 m in length). Previous monitoring has shown that the pH of the side tributary was significantly higher than that of the main channel and contains detectable levels of nitrate whereas the main channel had no detectable nitrate, and it is suspected that this side tributary significantly contributes to watershed export under base flow conditions. We expected that watershed's dominant water and chemical sources would vary with flow conditions, especially during summer thunderstorms. We hypothesized that the side tributary is the dominant source area under the normal base flow conditions of the summer (usually under 1 L/s) and that the main stem exerts dominance under the high flow conditions brought on by events. Daily water samples were taken throughout summer 2008 with three ISCO automated samplers: One ISCO was placed at the main stem of the stream, a second at the small internal tributary, and a third was placed at the weir. The samples were analyzed for pH, specific conductivity, and ANC, DOC, DON, and major anions and cations. The chemical data was compared to precipitation and rate of watershed flow calculated at each sampling hour to detect associations between chemical dominance and hydrological conditions. Under the base flow conditions of the summer, the chemistry of watershed outflow was dominated by that of the short side tributary, with lower acidity and higher nitrate levels than the longer main channel, but with notable contributions from the main channel. During each of the three high flow events that occurred over the summer, flow in the main channel increased dramatically and flow at the weir corresponded to temporarily increased acidity and decreased ANC. Preliminary nitrate data shows that a dilution response was associated with these events since there were significant declines in the nitrate levels of both the side tributary and watershed export during high flow conditions.

Variable disparity estimation based intermediate view reconstruction in dynamic flow allocation over EPON-based access networks

NASA Astrophysics Data System (ADS)

Bae, Kyung-Hoon; Lee, Jungjoon; Kim, Eun-Soo

2008-06-01

In this paper, a variable disparity estimation (VDE)-based intermediate view reconstruction (IVR) in dynamic flow allocation (DFA) over an Ethernet passive optical network (EPON)-based access network is proposed. In the proposed system, the stereoscopic images are estimated by a variable block-matching algorithm (VBMA), and they are transmitted to the receiver through DFA over EPON. This scheme improves a priority-based access network by converting it to a flow-based access network with a new access mechanism and scheduling algorithm, and then 16-view images are synthesized by the IVR using VDE. Some experimental results indicate that the proposed system improves the peak-signal-to-noise ratio (PSNR) to as high as 4.86 dB and reduces the processing time to 3.52 s. Additionally, the network service provider can provide upper limits of transmission delays by the flow. The modeling and simulation results, including mathematical analyses, from this scheme are also provided.

DIRECT NUMERICAL SIMULATION OF TRANSITIONAL FLOW IN A STENOSED CAROTID BIFURCATION

PubMed Central

Lee, Seung E.; Lee, Sang-Wook; Fischer, Paul F.; Bassiouny, Hisham S.; Loth, Francis

2008-01-01

The blood flow dynamics of a stenosed, subject-specific, carotid bifurcation were numerically simulated using the spectral element method. Pulsatile inlet conditions were based on in vivo color Doppler ultrasound measurements of blood velocity. The results demonstrated the transitional or weakly turbulent state of the blood flow, which featured rapid velocity and pressure fluctuations in the post-stenotic region of the internal carotid artery during systole and laminar flow during diastole. High-frequency vortex shedding was greatest downstream of the stenosis during the deceleration phase of systole. Velocity fluctuations had a frequency within the audible range of 100–300 Hz. Instantaneous wall shear stress within the stenosis was relatively high during systole (~25-45 Pa) compared to that in a healthy carotid. In addition, high spatial gradients of wall shear stress were present due to flow separation on the inner wall. Oscillatory flow reversal and low pressure were observed distal to the stenosis in the internal carotid artery. This study predicts the complex flow field, the turbulence levels and the distribution of the biomechanical stresses present in vivo within a stenosed carotid artery. PMID:18656199

Numerical Modelling and Prediction of Erosion Induced by Hydrodynamic Cavitation

NASA Astrophysics Data System (ADS)

Peters, A.; Lantermann, U.; el Moctar, O.

2015-12-01

The present work aims to predict cavitation erosion using a numerical flow solver together with a new developed erosion model. The erosion model is based on the hypothesis that collapses of single cavitation bubbles near solid boundaries form high velocity microjets, which cause sonic impacts with high pressure amplitudes damaging the surface. The erosion model uses information from a numerical Euler-Euler flow simulation to predict erosion sensitive areas and assess the erosion aggressiveness of the flow. The obtained numerical results were compared to experimental results from tests of an axisymmetric nozzle.

Exploring Flow Procedures for Diazonium Formation.

PubMed

Hu, Te; Baxendale, Ian R; Baumann, Marcus

2016-07-14

The synthesis of diazonium salts is historically an important transformation extensively utilized in dye manufacture. However the highly reactive nature of the diazonium functionality has additionally led to the development of many new reactions including several carbon-carbon bond forming processes. It is therefore highly desirable to determine optimum conditions for the formation of diazonium compounds utilizing the latest processing tools such as flow chemistry to take advantage of the increased safety and continuous manufacturing capabilities. Herein we report a series of flow-based procedures to prepare diazonium salts for subsequent in-situ consumption.

The Aeroacoustics and Aerodynamics of High-Speed Coanda Devices, Part 1: Conventional Arrangement of Exit Nozzle and Surface

NASA Astrophysics Data System (ADS)

Carpenter, P. W.; Green, P. N.

1997-12-01

The literature on high-speed Coanda flows and its applications is reviewed. The lack of basic information for design engineers is noted. The present paper is based on an investigation of the aeroacoustics and aerodynamics of the high-speed Coanda flow that is formed when a supersonic jet issues from a radial nozzle and adheres to a tulip-shaped body of revolution. Schlieren and other flow visualization techniques together with theoretical methods are used to reveal the various features of this complex flow field. The acoustic characteristics were obtained from measurements with an array of microphones in an anechoic chamber. The emphasis is placed on those features of the aerodynamics and aeroacoustics which may be of general interest.

Flow Asymmetric Propargylation: Development of Continuous Processes for the Preparation of a Chiral β-Amino Alcohol.

PubMed

Li, Hui; Sheeran, Jillian W; Clausen, Andrew M; Fang, Yuan-Qing; Bio, Matthew M; Bader, Scott

2017-08-01

The development of a flow chemistry process for asymmetric propargylation using allene gas as a reagent is reported. The connected continuous process of allene dissolution, lithiation, Li-Zn transmetallation, and asymmetric propargylation provides homopropargyl β-amino alcohol 1 with high regio- and diastereoselectivity in high yield. This flow process enables practical use of an unstable allenyllithium intermediate. The process uses the commercially available and recyclable (1S,2R)-N-pyrrolidinyl norephedrine as a ligand to promote the highly diastereoselective (32:1) propargylation. Judicious selection of mixers based on the chemistry requirement and real-time monitoring of the process using process analytical technology (PAT) enabled stable and scalable flow chemistry runs. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

An ab initio chemical reaction model for the direct simulation Monte Carlo study of non-equilibrium nitrogen flows.

PubMed

Mankodi, T K; Bhandarkar, U V; Puranik, B P

2017-08-28

A new ab initio based chemical model for a Direct Simulation Monte Carlo (DSMC) study suitable for simulating rarefied flows with a high degree of non-equilibrium is presented. To this end, Collision Induced Dissociation (CID) cross sections for N 2 +N 2 →N 2 +2N are calculated and published using a global complete active space self-consistent field-complete active space second order perturbation theory N 4 potential energy surface and quasi-classical trajectory algorithm for high energy collisions (up to 30 eV). CID cross sections are calculated for only a selected set of ro-vibrational combinations of the two nitrogen molecules, and a fitting scheme based on spectroscopic weights is presented to interpolate the CID cross section for all possible ro-vibrational combinations. The new chemical model is validated by calculating equilibrium reaction rate coefficients that can be compared well with existing shock tube and computational results. High-enthalpy hypersonic nitrogen flows around a cylinder in the transition flow regime are simulated using DSMC to compare the predictions of the current ab initio based chemical model with the prevailing phenomenological model (the total collision energy model). The differences in the predictions are discussed.

Loss reduction in axial-flow compressors through low-speed model testing

NASA Technical Reports Server (NTRS)

Wisler, D. C.

1984-01-01

A systematic procedure for reducing losses in axial-flow compressors is presented. In this procedure, a large, low-speed, aerodynamic model of a high-speed core compressor is designed and fabricated based on aerodynamic similarity principles. This model is then tested at low speed where high-loss regions associated with three-dimensional endwall boundary layers flow separation, leakage, and secondary flows can be located, detailed measurements made, and loss mechanisms determined with much greater accuracy and much lower cost and risk than is possible in small, high-speed compressors. Design modifications are made by using custom-tailored airfoils and vector diagrams, airfoil endbends, and modified wall geometries in the high-loss regions. The design improvements resulting in reduced loss or increased stall margin are then scaled to high speed. This paper describes the procedure and presents experimental results to show that in some cases endwall loss has been reduced by as much as 10 percent, flow separation has been reduced or eliminated, and stall margin has been substantially improved by using these techniques.

Evidence for gap flows in the Birch Creek Valley, Idaho

Treesearch

D. Finn; B. Reese; B. Butler; N. Wagenbrenner; K. L. Clawson; J. Rich; E. Russell; Z. Gao; H. Liu

2016-01-01

A field study was conducted of flows in the Birch Creek Valley in eastern Idaho. There is a distinct topographic constriction in the Birch Creek Valley that creates two subbasins: an upper and lower valley. The data were classified into one of three groups based on synoptic influence (weak/absent, high wind speeds, and other evidence of synoptic influence). Gap flows...

NeuroFlow: A General Purpose Spiking Neural Network Simulation Platform using Customizable Processors.

PubMed

Cheung, Kit; Schultz, Simon R; Luk, Wayne

2015-01-01

NeuroFlow is a scalable spiking neural network simulation platform for off-the-shelf high performance computing systems using customizable hardware processors such as Field-Programmable Gate Arrays (FPGAs). Unlike multi-core processors and application-specific integrated circuits, the processor architecture of NeuroFlow can be redesigned and reconfigured to suit a particular simulation to deliver optimized performance, such as the degree of parallelism to employ. The compilation process supports using PyNN, a simulator-independent neural network description language, to configure the processor. NeuroFlow supports a number of commonly used current or conductance based neuronal models such as integrate-and-fire and Izhikevich models, and the spike-timing-dependent plasticity (STDP) rule for learning. A 6-FPGA system can simulate a network of up to ~600,000 neurons and can achieve a real-time performance of 400,000 neurons. Using one FPGA, NeuroFlow delivers a speedup of up to 33.6 times the speed of an 8-core processor, or 2.83 times the speed of GPU-based platforms. With high flexibility and throughput, NeuroFlow provides a viable environment for large-scale neural network simulation.

NeuroFlow: A General Purpose Spiking Neural Network Simulation Platform using Customizable Processors

PubMed Central

Cheung, Kit; Schultz, Simon R.; Luk, Wayne

2016-01-01

NeuroFlow is a scalable spiking neural network simulation platform for off-the-shelf high performance computing systems using customizable hardware processors such as Field-Programmable Gate Arrays (FPGAs). Unlike multi-core processors and application-specific integrated circuits, the processor architecture of NeuroFlow can be redesigned and reconfigured to suit a particular simulation to deliver optimized performance, such as the degree of parallelism to employ. The compilation process supports using PyNN, a simulator-independent neural network description language, to configure the processor. NeuroFlow supports a number of commonly used current or conductance based neuronal models such as integrate-and-fire and Izhikevich models, and the spike-timing-dependent plasticity (STDP) rule for learning. A 6-FPGA system can simulate a network of up to ~600,000 neurons and can achieve a real-time performance of 400,000 neurons. Using one FPGA, NeuroFlow delivers a speedup of up to 33.6 times the speed of an 8-core processor, or 2.83 times the speed of GPU-based platforms. With high flexibility and throughput, NeuroFlow provides a viable environment for large-scale neural network simulation. PMID:26834542

Simultaneous ultrasound and photoacoustics based flow cytometry

NASA Astrophysics Data System (ADS)

Gnyawali, Vaskar; Strohm, Eric M.; Tsai, Scott S. H.; Kolios, Michael C.

2018-04-01

We have developed a flow cytometer based on simultaneous detection of ultrasound and photoacoustic waves from individual particles/cells flowing in a microfluidic channel. Our polydimethylsiloxane (PDMS) based hydrodynamic 3-dimensional (3D) flow-focusing microfluidic device contains a cross-junction channel, a micro-needle (ID 100 μm and OD 200 μm) insert, and a 3D printed frame to hold and align a high frequency (center frequency 375 MHz) ultrasound transducer. The focused flow passes through a narrow focal zone with lateral and axial focal lengths of 6-8 μm and 15-20 μm, respectively. Both the lateral and axial alignments are achieved by screwing the transducer to the frame onto the PDMS device. Individual particles pass through an interrogation zone in the microfluidic channel with a collinearly aligned ultrasound transducer and a focused 532 nm wavelength laser beam. The particles are simultaneously insonified by high-frequency ultrasound and irradiated by a laser beam. The ultrasound backscatter and laser generated photoacoustic waves are detected for each passing particle. The backscattered ultrasound and photoacoustic signal are strongly dependent on the size, morphology, mechanical properties, and material properties of the flowing particles; these parameters can be extracted by analyzing unique features in the power spectrum of the signals. Frequencies less than 100 MHz do not have these unique spectral signatures. We show that we can reliably distinguish between different particles in a sample using the acoustic-based flow cytometer. This technique, when extended to biomedical applications, allows us to rapidly analyze the spectral signatures from individual single cells of a large cell population, with applications towards label-free detection and characterization of healthy and diseased cells.

The Characteristics of Heat Flow in the Ryukyu Trench-Arc-Basin System: Constraints on Thermal Structure and Evolution of the Okinawa Trough

NASA Astrophysics Data System (ADS)

Zhang, L.

2017-12-01

Heat flow is an important constraint to study the thermal structure and evolution in modeling experiments. Based on the surface heat flow map and recent geochemistry results, a 2D transient heat conduction-advection model is used to investigate how the effects of sedimentation rate, magmatic intrusion, extension duration and rate on the surface heat flow distribution of the Okinawa Trough. Surface heat flow distribution map is interpolated based on a data set with 664 measurements in the Ryukyu trench-arc-basin system. The map shows an obviously correspondence between heat flows and tectonic zones, characterized by belts in E-W and blocks in S-N. The heat flow is extremely high and variable in the central Okinawa Trough (COT). The lowest heat values are distributed in the northwest of West Philippine Sea near the Ryukyu Trench. This phenomenon is likely related to increasing hydrothermal circulation of cold water into the upper portion of the incoming plate because of bend-faulting and little sediment coverage. Simulation results show that (1) High sedimentation rate can reduce heat flow by 30-35 % in the southern OT. (2) The sedimentation-corrected heat flow indicates that mantle upwelling occurred in the whole OT. The isotherm of 1000°C reaches to the depth of 19 km in the axil of the COT after 10 Ma. (3) The heat flow can be improved drastically by dyke intrusion along normal faults, but subsequent decreases rapidly about 15% after 0.1 Ma, which indicates the age of dyke intrusion under the Iheya area is younger than 0.5 Ma, and the depth is shallower than 2 km. Moreover, the magma fluid upward migrated along the magma conduits is required for the extremely high heat flow and its Darcy velocity can reach to 9 cm/yr. Based on the distribution of heat flow, we suggest that there is a different evolution model between the central- northern OT and the southern. The time of rifting in the NOT-COT began at 10 Ma with the mean rate of 0.4 cm/yr, while the rifting of the SOT started from 6 Ma with higher rate of 0.6 cm/yr.

Flow field and friction factor of slush nitrogen in a horizontal circular pipe

NASA Astrophysics Data System (ADS)

Jin, Tao; Li, Yijian; Wu, Shuqin; Wei, Jianjian

2018-04-01

Slush nitrogen is the low-temperature two-phase fluid with solid nitrogen particle suspended in the liquid nitrogen. The flow characteristics of slush nitrogen in a horizontal pipe with the diameter of 16 mm have been experimentally and numerically investigated, under the operating conditions with the inlet flow velocity of 0-4 m/s and the solid volume fraction of 0-23%. The numerical results for pressure drop agree well with those of the experiments, with the relative errors of ±5%. The experimental and numerical results both show that the pressure drop of slush nitrogen is greater than that of subcooled liquid nitrogen and rises with the increasing particle concentration, under the working conditions in present work. Based on the simulation result, the flow pattern evolution of slush nitrogen with the increasing slush Reynolds number has been discussed, which can be classified into homogenous flow, heterogeneous flow and moving bed. The slush effective viscosity and the slush Reynolds number are calculated with Cheng & Law formula, which includes the effects of particle shape, size and type and has a high accuracy for high concentration slurries. Based on the slush Reynolds number, an experimental empirical correlation considering particle conditions for the friction factor of slush nitrogen flow is obtained.

Circumventing Imprecise Geometric Information and Development of a Unified Modeling Technique for Various Flow Regimes in Capillary Tubes

NASA Astrophysics Data System (ADS)

Abbasi, Bahman

2012-11-01

Owing to their manufacturability and reliability, capillary tubes are the most common expansion devices in household refrigerators. Therefore, investigating flow properties in the capillary tubes is of immense appeal in the said business. The models to predict pressure drop in two-phase internal flows invariably rely upon highly precise geometric information. The manner in which capillary tubes are manufactured makes them highly susceptible to geometric imprecisions, which renders geometry-based models unreliable to the point of obsoleteness. Aware of the issue, manufacturers categorize capillary tubes based on Nitrogen flow rate through them. This categorization method presents an opportunity to substitute geometric details with Nitrogen flow data as the basis for customized models. The simulation tools developed by implementation of this technique have the singular advantage of being applicable across flow regimes. Thus the error-prone process of identifying compatible correlations is eliminated. Equally importantly, compressibility and chocking effects can be incorporated in the same model. The outcome is a standalone correlation that provides accurate predictions, regardless of any particular fluid or flow regime. Thereby, exploratory investigations for capillary tube design and optimization are greatly simplified. Bahman Abbasi, Ph.D., is Lead Advanced Systems Engineer at General Electric Appliances in Louisville, KY. He conducts research projects across disciplines in the household refrigeration industry.

A stochastic two-scale model for pressure-driven flow between rough surfaces

PubMed Central

Larsson, Roland; Lundström, Staffan; Wall, Peter; Almqvist, Andreas

2016-01-01

Seal surface topography typically consists of global-scale geometric features as well as local-scale roughness details and homogenization-based approaches are, therefore, readily applied. These provide for resolving the global scale (large domain) with a relatively coarse mesh, while resolving the local scale (small domain) in high detail. As the total flow decreases, however, the flow pattern becomes tortuous and this requires a larger local-scale domain to obtain a converged solution. Therefore, a classical homogenization-based approach might not be feasible for simulation of very small flows. In order to study small flows, a model allowing feasibly-sized local domains, for really small flow rates, is developed. Realization was made possible by coupling the two scales with a stochastic element. Results from numerical experiments, show that the present model is in better agreement with the direct deterministic one than the conventional homogenization type of model, both quantitatively in terms of flow rate and qualitatively in reflecting the flow pattern. PMID:27436975

Poiseuille, thermal transpiration and Couette flows of a rarefied gas between plane parallel walls with nonuniform surface properties in the transverse direction and their reciprocity relations

NASA Astrophysics Data System (ADS)

Doi, Toshiyuki

2018-04-01

Slow flows of a rarefied gas between two plane parallel walls with nonuniform surface properties are studied based on kinetic theory. It is assumed that one wall is a diffuse reflection boundary and the other wall is a Maxwell-type boundary whose accommodation coefficient varies periodically in the direction perpendicular to the flow. The time-independent Poiseuille, thermal transpiration and Couette flows are considered. The flow behavior is numerically studied based on the linearized Bhatnagar-Gross-Krook-Welander model of the Boltzmann equation. The flow field, the mass and heat flow rates in the gas, and the tangential force acting on the wall surface are studied over a wide range of the gas rarefaction degree and the parameters characterizing the distribution of the accommodation coefficient. The locally convex velocity distribution is observed in Couette flow of a highly rarefied gas, similarly to Poiseuille flow and thermal transpiration. The reciprocity relations are numerically confirmed over a wide range of the flow parameters.

Modified Beer-Lambert law for blood flow

PubMed Central

Baker, Wesley B.; Parthasarathy, Ashwin B.; Busch, David R.; Mesquita, Rickson C.; Greenberg, Joel H.; Yodh, A. G.

2014-01-01

We develop and validate a Modified Beer-Lambert law for blood flow based on diffuse correlation spectroscopy (DCS) measurements. The new formulation enables blood flow monitoring from temporal intensity autocorrelation function data taken at single or multiple delay-times. Consequentially, the speed of the optical blood flow measurement can be substantially increased. The scheme facilitates blood flow monitoring of highly scattering tissues in geometries wherein light propagation is diffusive or non-diffusive, and it is particularly well-suited for utilization with pressure measurement paradigms that employ differential flow signals to reduce contributions of superficial tissues. PMID:25426330

High-resolution numerical approximation of traffic flow problems with variable lanes and free-flow velocities.

PubMed

Zhang, Peng; Liu, Ru-Xun; Wong, S C

2005-05-01

This paper develops macroscopic traffic flow models for a highway section with variable lanes and free-flow velocities, that involve spatially varying flux functions. To address this complex physical property, we develop a Riemann solver that derives the exact flux values at the interface of the Riemann problem. Based on this solver, we formulate Godunov-type numerical schemes to solve the traffic flow models. Numerical examples that simulate the traffic flow around a bottleneck that arises from a drop in traffic capacity on the highway section are given to illustrate the efficiency of these schemes.

GREEN + IDMaps: A practical soulution for ensuring fairness in a biased internet

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kapadia, A. C.; Thulasidasan, S.; Feng, W. C.

2002-01-01

GREEN is a proactive queue-management (PQM) algorithm that removes TCP's bias against connections with longer round-trip times, while maintaining high link utilization and low packet-loss. GREEN applies knowledge of the steady-state behavior of TCP connections to proactively drop packets, thus preventing congestion from ever occurring. As a result, GREEN ensures much higher fairness between flows than other active queue management schemes like Flow Random Early Drop (FRED) and Stochastic Fair Blue (SFB), which suffer in topologies where a large number of flows have widely varying round-trip times. GREEN'S performance relies on its ability to gauge a flow's round-trip time (RTT).more » In previous work, we presented results for an ideal GREEN router which has accurate RTT information for a flow. In this paper, we present a practical solution based on IDMaps, an Internet distance-estimation service, and compare its performance to an ideal GREEN router. We show that a solution based on IDMaps is practical and maintains high fairness and link utilization, and low packet-loss rates.« less

qFlow Cytometry-Based Receptoromic Screening: A High-Throughput Quantification Approach Informing Biomarker Selection and Nanosensor Development.

PubMed

Chen, Si; Weddell, Jared; Gupta, Pavan; Conard, Grace; Parkin, James; Imoukhuede, Princess I

2017-01-01

Nanosensor-based detection of biomarkers can improve medical diagnosis; however, a critical factor in nanosensor development is deciding which biomarker to target, as most diseases present several biomarkers. Biomarker-targeting decisions can be informed via an understanding of biomarker expression. Currently, immunohistochemistry (IHC) is the accepted standard for profiling biomarker expression. While IHC provides a relative mapping of biomarker expression, it does not provide cell-by-cell readouts of biomarker expression or absolute biomarker quantification. Flow cytometry overcomes both these IHC challenges by offering biomarker expression on a cell-by-cell basis, and when combined with calibration standards, providing quantitation of biomarker concentrations: this is known as qFlow cytometry. Here, we outline the key components for applying qFlow cytometry to detect biomarkers within the angiogenic vascular endothelial growth factor receptor family. The key aspects of the qFlow cytometry methodology include: antibody specificity testing, immunofluorescent cell labeling, saturation analysis, fluorescent microsphere calibration, and quantitative analysis of both ensemble and cell-by-cell data. Together, these methods enable high-throughput quantification of biomarker expression.

Export of nutrients and major ionic solutes from a rain forest catchment in the Central Amazon Basin

NASA Astrophysics Data System (ADS)

Lesack, Lance F. W.

1993-03-01

The relative roles of base flow runoff versus storm flow runoff versus subsurface outflow in controlling total export of solutes from a 23.4-ha catchment of undisturbed rain forest in the central Amazon Basin were evaluated from water and solute flux measurements performed over a 1 year period. Solutes exported via 173 storms during the study were estimated from stream water samples collected during base flow conditions and during eight storms, and by utilizing a hydrograph separation technique in combination with a mixing model to partition storm flow from base flow fluxes. Solutes exported by subsurface outflow were estimated from groundwater samples from three nests of piezometers installed into the streambed, and concurrent measurements of hydraulic conductivity and hydraulic head gradients. Base flow discharge represented 92% of water outflow from the basin and was the dominant pathway of solute export. Although storm flow discharge represented only 5% of total water outflow, storm flow solute fluxes represented up to 25% of the total annual export flux, though for many solutes the portion was less. Subsurface outflow represented only 2.5% of total water outflow, and subsurface solute fluxes never represented more than 5% of the total annual export flux. Measurement errors were relatively high for storm flow and subsurface outflow fluxes, but cumulative measurement errors associated with the total solute fluxes exported from the catchment, in most cases, ranged from only ±7% to 14% because base flow fluxes were measured relatively well. The export fluxes of most solutes are substantially less than previously reported for comparable small catchments in the Amazon basin, and these differences cannot be reconciled by the fact that storm flow and subsurface outflows were not appropriately measured in previous studies.

Advances in the U.S. Navy Non-hydrostatic Unified Model of the Atmosphere (NUMA): LES as a Stabilization Methodology for High-Order Spectral Elements in the Simulation of Deep Convection

NASA Astrophysics Data System (ADS)

Marras, Simone; Giraldo, Frank

2015-04-01

The prediction of extreme weather sufficiently ahead of its occurrence impacts society as a whole and coastal communities specifically (e.g. Hurricane Sandy that impacted the eastern seaboard of the U.S. in the fall of 2012). With the final goal of solving hurricanes at very high resolution and numerical accuracy, we have been developing the Non-hydrostatic Unified Model of the Atmosphere (NUMA) to solve the Euler and Navier-Stokes equations by arbitrary high-order element-based Galerkin methods on massively parallel computers. NUMA is a unified model with respect to the following criteria: (a) it is based on unified numerics in that element-based Galerkin methods allow the user to choose between continuous (spectral elements, CG) or discontinuous Galerkin (DG) methods and from a large spectrum of time integrators, (b) it is unified across scales in that it can solve flow in limited-area mode (flow in a box) or in global mode (flow on the sphere). NUMA is the dynamical core that powers the U.S. Naval Research Laboratory's next-generation global weather prediction system NEPTUNE (Navy's Environmental Prediction sysTem Utilizing the NUMA corE). Because the solution of the Euler equations by high order methods is prone to instabilities that must be damped in some way, we approach the problem of stabilization via an adaptive Large Eddy Simulation (LES) scheme meant to treat such instabilities by modeling the sub-grid scale features of the flow. The novelty of our effort lies in the extension to high order spectral elements for low Mach number stratified flows of a method that was originally designed for low order, adaptive finite elements in the high Mach number regime [1]. The Euler equations are regularized by means of a dynamically adaptive stress tensor that is proportional to the residual of the unperturbed equations. Its effect is close to none where the solution is sufficiently smooth, whereas it increases elsewhere, with a direct contribution to the stabilization of the otherwise oscillatory solution. As a first step toward the Large Eddy Simulation of a hurricane, we verify the model via a high-order and high resolution idealized simulation of deep convection on the sphere. References [1] M. Nazarov and J. Hoffman (2013) Residual-based artificial viscosity for simulation of turbulent compressible flow using adaptive finite element methods Int. J. Numer. Methods Fluids, 71:339-357

A high-order vertex-based central ENO finite-volume scheme for three-dimensional compressible flows

DOE PAGES

Charest, Marc R.J.; Canfield, Thomas R.; Morgan, Nathaniel R.; ...

2015-03-11

High-order discretization methods offer the potential to reduce the computational cost associated with modeling compressible flows. However, it is difficult to obtain accurate high-order discretizations of conservation laws that do not produce spurious oscillations near discontinuities, especially on multi-dimensional unstructured meshes. A novel, high-order, central essentially non-oscillatory (CENO) finite-volume method that does not have these difficulties is proposed for tetrahedral meshes. The proposed unstructured method is vertex-based, which differs from existing cell-based CENO formulations, and uses a hybrid reconstruction procedure that switches between two different solution representations. It applies a high-order k-exact reconstruction in smooth regions and a limited linearmore » reconstruction when discontinuities are encountered. Both reconstructions use a single, central stencil for all variables, making the application of CENO to arbitrary unstructured meshes relatively straightforward. The new approach was applied to the conservation equations governing compressible flows and assessed in terms of accuracy and computational cost. For all problems considered, which included various function reconstructions and idealized flows, CENO demonstrated excellent reliability and robustness. Up to fifth-order accuracy was achieved in smooth regions and essentially non-oscillatory solutions were obtained near discontinuities. The high-order schemes were also more computationally efficient for high-accuracy solutions, i.e., they took less wall time than the lower-order schemes to achieve a desired level of error. In one particular case, it took a factor of 24 less wall-time to obtain a given level of error with the fourth-order CENO scheme than to obtain the same error with the second-order scheme.« less

Frequency-Domain Characterization of Optic Flow and Vision-Based Ocellar Sensing for Rotational Motion

DTIC Science & Technology

2017-04-01

complementary fusion: Fourth-order Butterworth filter was used to high -pass ocelli and low-pass optic flow. The normalized cutoff frequency had to be kept...information introduced by luminance change. The high - frequency cutoff was added to reject the flickering noise for indoor usage. The filtered signals from the...function of the low- pass filter is to attenuate high - frequency noise. The final band-pass filter transfer function is in Eq. 2. (()

Rapid and Sensitive Detection of Protein Biomarker Using a Portable Fluorescence Biosensor based on Quantum Dots and a Lateral Flow Test Strip

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Zhaohui; Wang, Ying; Wang, Jun

2010-08-15

A portable fluorescence biosensor with rapid and ultrasensitive response for trace protein has been built up with quantum dots and lateral flow test strip. The superior signal brightness and high photostability of quantum dots are combined with the promising advantages of lateral flow test strip and resulted in high sensitivity, selectivity and speedy for protein detection. Nitrated ceruloplasmin, a significant biomarker for cardiovascular disease, lung cancer and stress response to smoking, was used as model protein to demonstrate the good performances of this proposed Qdot-based lateral flow test strip. Quantitative detection of nitrated ceruloplasmin was realized by recording the fluorescencemore » intensity of quantum dots captured on the test line. Under optimal conditions, this portable fluorescence biosensor displays rapid responses for nitrated ceruloplasmin in wide dynamic range with a detection limit of 0.1ng/mL (S/N=3). Furthermore, the biosensor was successfully utilized for spiked human plasma sample detection with the concentration as low as 1ng/mL. The results demonstrate that the quantum dot-based lateral flow test strip is capable for rapid, sensitive, and quantitative detection of nitrated ceruloplasmin and hold a great promise for point-of-care and in field analysis of other protein biomarkers.« less

Characterization of Arcjet Flows Using Laser-Induced Fluorescence

NASA Technical Reports Server (NTRS)

Bamford, Douglas J.; O'Keefe, Anthony; Babikian, Dikran S.; Stewart, David A.; Strawa, Anthony W.

1995-01-01

A sensor based on laser-induced fluorescence has been installed at the 20-MW NASA Ames Aerodynamic Heating Facility. The sensor has provided new, quantitative, real-time information about properties of the arcjet flow in the highly dissociated, partially ionized, nonequilibrium regime. Number densities of atomic oxygen, flow velocities, heavy particle translational temperatures, and collisional quenching rates have been measured. These results have been used to test and refine computational models of the arcjet flow. The calculated number densities, translational temperatures, and flow velocities are in moderately good agreement with experiment

Planar temperature measurement in compressible flows using laser-induced iodine fluorescence

NASA Technical Reports Server (NTRS)

Hartfield, Roy J., Jr.; Hollo, Steven D.; Mcdaniel, James C.

1991-01-01

A laser-induced iodine fluorescence technique that is suitable for the planar measurement of temperature in cold nonreacting compressible air flows is investigated analytically and demonstrated in a known flow field. The technique is based on the temperature dependence of the broadband fluorescence from iodine excited by the 514-nm line of an argon-ion laser. Temperatures ranging from 165 to 245 K were measured in the calibration flow field. This technique makes complete, spatially resolved surveys of temperature practical in highly three-dimensional, low-temperature compressible flows.

Electrical resistance tomography to monitor unsaturated moisture flow in cementitious materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hallaji, Milad; Seppänen, Aku; Pour-Ghaz, Mohammad, E-mail: mpourghaz@ncsu.edu

2015-03-15

Traditionally the electrically-based assessment of the moisture flow in cement-based materials relies on two- or four-point measurements. In this paper, imaging of moisture distribution with electrical resistance tomography (ERT) is considered. Especially, the aim is to study whether ERT could give information on unsaturated moisture flows in cases where the flow is non-uniform. In the experiment, the specimens are monitored with ERT during the water ingress. The ERT reconstructions are compared with neutron radiographs, which provide high resolution information on the 2D distribution of the moisture. The results indicate that ERT is able to detect the moisture movement and tomore » show approximately the shape and position of the water front even if the flow is nonuniform.« less

Flash chemistry: flow chemistry that cannot be done in batch.

PubMed

Yoshida, Jun-ichi; Takahashi, Yusuke; Nagaki, Aiichiro

2013-11-04

Flash chemistry based on high-resolution reaction time control using flow microreactors enables chemical reactions that cannot be done in batch and serves as a powerful tool for laboratory synthesis of organic compounds and for production in chemical and pharmaceutical industries.

Highly selective deuteration of pharmaceutically relevant nitrogen-containing heterocycles: a flow chemistry approach.

PubMed

Ötvös, Sándor B; Mándity, István M; Fülöp, Ferenc

2011-08-01

A simple and efficient flow-based technique is reported for the catalytic deuteration of several model nitrogen-containing heterocyclic compounds which are important building blocks of pharmacologically active materials. A continuous flow reactor was used in combination with on-demand pressure-controlled electrolytic D(2) production. The D(2) source was D(2)O, the consumption of which was very low. The experimental set-up allows the fine-tuning of pressure, temperature, and flow rate so as to determine the optimal conditions for the deuteration reactions. The described procedure lacks most of the drawbacks of the conventional batch deuteration techniques, and additionally is highly selective and reproducible.

Multigrid schemes for viscous hypersonic flows

NASA Technical Reports Server (NTRS)

Swanson, R. C.; Radespiel, R.

1993-01-01

Several multigrid schemes are considered for the numerical computation of viscous hypersonic flows. For each scheme, the basic solution algorithm employs upwind spatial discretization with explicit multistage time stepping. Two-level versions of the various multigrid algorithms are applied to the two-dimensional advection equation, and Fourier analysis is used to determine their damping properties. The capabilities of the multigrid methods are assessed by solving two different hypersonic flow problems. Some new multigrid schemes, based on semicoarsening strategies, are shown to be quite effective in relieving the stiffness caused by the high-aspect-ratio cells required to resolve high Reynolds number flows. These schemes exhibit good convergence rates for Reynolds numbers up to 200 x 10(exp 6).

Linking water quality and quantity in environmental flow assessment in deteriorated ecosystems: a food web view.

PubMed

Chen, He; Ma, Lekuan; Guo, Wei; Yang, Ying; Guo, Tong; Feng, Cheng

2013-01-01

Most rivers worldwide are highly regulated by anthropogenic activities through flow regulation and water pollution. Environmental flow regulation is used to reduce the effects of anthropogenic activities on aquatic ecosystems. Formulating flow alteration-ecological response relationships is a key factor in environmental flow assessment. Traditional environmental flow models are characterized by natural relationships between flow regimes and ecosystem factors. However, food webs are often altered from natural states, which disturb environmental flow assessment in such ecosystems. In ecosystems deteriorated by heavy anthropogenic activities, the effects of environmental flow regulation on species are difficult to assess with current modeling approaches. Environmental flow management compels the development of tools that link flow regimes and food webs in an ecosystem. Food web approaches are more suitable for the task because they are more adaptive for disordered multiple species in a food web deteriorated by anthropogenic activities. This paper presents a global method of environmental flow assessment in deteriorated aquatic ecosystems. Linkages between flow regimes and food web dynamics are modeled by incorporating multiple species into an ecosystem to explore ecosystem-based environmental flow management. The approach allows scientists and water resources managers to analyze environmental flows in deteriorated ecosystems in an ecosystem-based way.

Deep Packet/Flow Analysis using GPUs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gong, Qian; Wu, Wenji; DeMar, Phil

Deep packet inspection (DPI) faces severe performance challenges in high-speed networks (40/100 GE) as it requires a large amount of raw computing power and high I/O throughputs. Recently, researchers have tentatively used GPUs to address the above issues and boost the performance of DPI. Typically, DPI applications involve highly complex operations in both per-packet and per-flow data level, often in real-time. The parallel architecture of GPUs fits exceptionally well for per-packet network traffic processing. However, for stateful network protocols such as TCP, their data stream need to be reconstructed in a per-flow level to deliver a consistent content analysis. Sincemore » the flow-centric operations are naturally antiparallel and often require large memory space for buffering out-of-sequence packets, they can be problematic for GPUs, whose memory is normally limited to several gigabytes. In this work, we present a highly efficient GPU-based deep packet/flow analysis framework. The proposed design includes a purely GPU-implemented flow tracking and TCP stream reassembly. Instead of buffering and waiting for TCP packets to become in sequence, our framework process the packets in batch and uses a deterministic finite automaton (DFA) with prefix-/suffix- tree method to detect patterns across out-of-sequence packets that happen to be located in different batches. In conclusion, evaluation shows that our code can reassemble and forward tens of millions of packets per second and conduct a stateful signature-based deep packet inspection at 55 Gbit/s using an NVIDIA K40 GPU.« less

Implicit gas-kinetic unified algorithm based on multi-block docking grid for multi-body reentry flows covering all flow regimes

NASA Astrophysics Data System (ADS)

Peng, Ao-Ping; Li, Zhi-Hui; Wu, Jun-Lin; Jiang, Xin-Yu

2016-12-01

Based on the previous researches of the Gas-Kinetic Unified Algorithm (GKUA) for flows from highly rarefied free-molecule transition to continuum, a new implicit scheme of cell-centered finite volume method is presented for directly solving the unified Boltzmann model equation covering various flow regimes. In view of the difficulty in generating the single-block grid system with high quality for complex irregular bodies, a multi-block docking grid generation method is designed on the basis of data transmission between blocks, and the data structure is constructed for processing arbitrary connection relations between blocks with high efficiency and reliability. As a result, the gas-kinetic unified algorithm with the implicit scheme and multi-block docking grid has been firstly established and used to solve the reentry flow problems around the multi-bodies covering all flow regimes with the whole range of Knudsen numbers from 10 to 3.7E-6. The implicit and explicit schemes are applied to computing and analyzing the supersonic flows in near-continuum and continuum regimes around a circular cylinder with careful comparison each other. It is shown that the present algorithm and modelling possess much higher computational efficiency and faster converging properties. The flow problems including two and three side-by-side cylinders are simulated from highly rarefied to near-continuum flow regimes, and the present computed results are found in good agreement with the related DSMC simulation and theoretical analysis solutions, which verify the good accuracy and reliability of the present method. It is observed that the spacing of the multi-body is smaller, the cylindrical throat obstruction is greater with the flow field of single-body asymmetrical more obviously and the normal force coefficient bigger. While in the near-continuum transitional flow regime of near-space flying surroundings, the spacing of the multi-body increases to six times of the diameter of the single-body, the interference effects of the multi-bodies tend to be negligible. The computing practice has confirmed that it is feasible for the present method to compute the aerodynamics and reveal flow mechanism around complex multi-body vehicles covering all flow regimes from the gas-kinetic point of view of solving the unified Boltzmann model velocity distribution function equation.

Braided river flow and invasive vegetation dynamics in the Southern Alps, New Zealand.

PubMed

Caruso, Brian S; Edmondson, Laura; Pithie, Callum

2013-07-01

In mountain braided rivers, extreme flow variability, floods and high flow pulses are fundamental elements of natural flow regimes and drivers of floodplain processes, understanding of which is essential for management and restoration. This study evaluated flow dynamics and invasive vegetation characteristics and changes in the Ahuriri River, a free-flowing braided, gravel-bed river in the Southern Alps of New Zealand's South Island. Sixty-seven flow metrics based on indicators of hydrologic alteration and environmental flow components (extreme low flows, low flows, high flow pulses, small floods and large floods) were analyzed using a 48-year flow record. Changes in the areal cover of floodplain and invasive vegetation classes and patch characteristics over 20 years (1991-2011) were quantified using five sets of aerial photographs, and the correlation between flow metrics and cover changes were evaluated. The river exhibits considerable hydrologic variability characteristic of mountain braided rivers, with large variation in floods and other flow regime metrics. The flow regime, including flood and high flow pulses, has variable effects on floodplain invasive vegetation, and creates dynamic patch mosaics that demonstrate the concepts of a shifting mosaic steady state and biogeomorphic succession. As much as 25 % of the vegetation cover was removed by the largest flood on record (570 m(3)/s, ~50-year return period), with preferential removal of lupin and less removal of willow. However, most of the vegetation regenerated and spread relatively quickly after floods. Some flow metrics analyzed were highly correlated with vegetation cover, and key metrics included the peak magnitude of the largest flood, flood frequency, and time since the last flood in the interval between photos. These metrics provided a simple multiple regression model of invasive vegetation cover in the aerial photos evaluated. Our analysis of relationships among flow regimes and invasive vegetation cover has implications for braided rivers impacted by hydroelectric power production, where increases in invasive vegetation cover are typically greater than in unimpacted rivers.

Polyvinylpyrrolidone-based semi-interpenetrating polymer networks as highly selective and chemically stable membranes for all vanadium redox flow batteries

NASA Astrophysics Data System (ADS)

Zeng, L.; Zhao, T. S.; Wei, L.; Zeng, Y. K.; Zhang, Z. H.

2016-09-01

Vanadium redox flow batteries (VRFBs) with their high flexibility in configuration and operation, as well as long cycle life are competent for the requirement of future energy storage systems. Nevertheless, due to the application of perfluorinated membranes, VRFBs are plagued by not only the severe migration issue of vanadium ions, but also their high cost. Herein, we fabricate semi-interpenetrating polymer networks (SIPNs), consisting of cross-linked polyvinylpyrrolidone (PVP) and polysulfone (PSF), as alternative membranes for VRFBs. It is demonstrated that the PVP-based SIPNs exhibit extremely low vanadium permeabilities, which contribute to the well-established hydrophilic/hydrophobic microstructures and the Donnan exclusion effect. As a result, the coulombic efficiencies of VRFBs with PVP-based SIPNs reach almost 100% at 40 mA cm-2 to 100 mA cm-2; the energy efficiencies are more than 3% higher than those of VRFBs with Nafion 212. More importantly, the PVP-based SIPNs exhibit a superior chemical stability, as demonstrated both by an ex situ immersion test and continuously cycling test. Hence, all the characterizations and performance tests reported here suggest that PVP-based SIPNs are a promising alternative membrane for redox flow batteries to achieve superior cell performance and excellent cycling stability at the fraction of the cost of perfluorinated membranes.

Spiral Flow Phantom for Ultrasound Flow Imaging Experimentation.

PubMed

Yiu, Billy Y S; Yu, Alfred C H

2017-12-01

As new ultrasound flow imaging methods are being developed, there is a growing need to devise appropriate flow phantoms that can holistically assess the accuracy of the derived flow estimates. In this paper, we present a novel spiral flow phantom design whose Archimedean spiral lumen naturally gives rise to multi-directional flow over all possible angles (i.e., from 0° to 360°). Developed using lost-core casting principles, the phantom geometry comprised a three-loop spiral (4-mm diameter and 5-mm pitch), and it was set to operate in steady flow mode (3 mL/s flow rate). After characterizing the flow pattern within the spiral vessel using computational fluid dynamics (CFD) simulations, the phantom was applied to evaluate the performance of color flow imaging (CFI) and high-frame-rate vector flow imaging. Significant spurious coloring artifacts were found when using CFI to visualize flow in the spiral phantom. In contrast, using vector flow imaging (least-squares multi-angle Doppler based on a three-transmit and three-receive configuration), we observed consistent depiction of flow velocity magnitude and direction within the spiral vessel lumen. The spiral flow phantom was also found to be a useful tool in facilitating demonstration of dynamic flow visualization based on vector projectile imaging. Overall, these results demonstrate the spiral flow phantom's practical value in analyzing the efficacy of ultrasound flow estimation methods.

Dense Pyroclastic Flows of the 16 -17 August 2006 Eruption of Tungurahua Volcano, Ecuador

NASA Astrophysics Data System (ADS)

Hall, M. L.; Mothes, P. A.; Ramon, P.; Arellano, S.; Barba, D.; Palacios, P.

2007-05-01

The 16-17 August 2006 eruption of Tungurahua volcano in central Ecuador was preceded by 7 years of threatening activity and finally a VEI=2 eruption on 14-15 July 2006. The larger August eruption witnessed tens of pyroclastic flows that descended 17 different channels up to 8.5 km to the volcano's base on the NW, N, W, and SW sides. Tungurahua (5023m) is a steep-sided, low SiO2 andesitic volcano with 2600 to 3200m of relief. The initial, small nuee ardentes began around 1700hr (local time), the larger flows occurred between 2147hr and 0100hr (17 Aug.), and a total of 31 events were indicated by seismic signals. The deposits of three distinct flow cycles are recognized at the NW base of the cone. On the Los Pajaros depositional fan, deposits of flows 1 and 2 are widespread laterally (<600m) and have low-aspect morphologies with low snouts and without levees. Their outer surfaces are covered with accessory > juvenile clasts that mainly range from 15 to 25cm in diameter, conversely their interiors are comprised of 40-42% clasts of 1-25cm size and a matrix (58-60%) of sand-size grains. The earlier flow 1 was accompanied by an ash cloud surge that leveled, but did not scorch, all trees, brush, even metal antenna posts, leaving a 1-10cm thick sandy ash layer upon flow 1's deposit. On the fan as well as in gullies on the upper flanks, flow 3 deposits form long narrow lobes with 1-2m high frontal snouts that are followed by empty flow channels, 5-15m wide, bounded by parallel levees 1-1.5m high. Within these channels subsequent flow lobes are found as remnant pulses. Unlike flows 1 and 2, flow 3 lobes are covered with 0.5-3m cauliflower-shaped, slightly vesiculated bombs that are rarely abraded; the deposit's interior has a 45% sandy matrix. During the climatic eruptive phase continuous lava fountaining, 500-700m high, and crater spilling likely fed a continual stream of fragmented lava onto the cone's upper steep flanks, from which dense pyroclastic mass flows were initiated by gravity. Flows 1 and 2 were more fluidized (due to entrained air and fines), faster, and had wider lateral extents. Flow 3 was poorly fluidized, highly channelized, and behaved more like an inertial granular flow that formed as a continuous avalanche stream that separated into consecutive pulses along the runout channel.

Development and application of computational aerothermodynamics flowfield computer codes

NASA Technical Reports Server (NTRS)

Venkatapathy, Ethiraj

1994-01-01

Research was performed in the area of computational modeling and application of hypersonic, high-enthalpy, thermo-chemical nonequilibrium flow (Aerothermodynamics) problems. A number of computational fluid dynamic (CFD) codes were developed and applied to simulate high altitude rocket-plume, the Aeroassist Flight Experiment (AFE), hypersonic base flow for planetary probes, the single expansion ramp model (SERN) connected with the National Aerospace Plane, hypersonic drag devices, hypersonic ramp flows, ballistic range models, shock tunnel facility nozzles, transient and steady flows in the shock tunnel facility, arc-jet flows, thermochemical nonequilibrium flows around simple and complex bodies, axisymmetric ionized flows of interest to re-entry, unsteady shock induced combustion phenomena, high enthalpy pulsed facility simulations, and unsteady shock boundary layer interactions in shock tunnels. Computational modeling involved developing appropriate numerical schemes for the flows on interest and developing, applying, and validating appropriate thermochemical processes. As part of improving the accuracy of the numerical predictions, adaptive grid algorithms were explored, and a user-friendly, self-adaptive code (SAGE) was developed. Aerothermodynamic flows of interest included energy transfer due to strong radiation, and a significant level of effort was spent in developing computational codes for calculating radiation and radiation modeling. In addition, computational tools were developed and applied to predict the radiative heat flux and spectra that reach the model surface.

Data flow modeling techniques

NASA Technical Reports Server (NTRS)

Kavi, K. M.

1984-01-01

There have been a number of simulation packages developed for the purpose of designing, testing and validating computer systems, digital systems and software systems. Complex analytical tools based on Markov and semi-Markov processes have been designed to estimate the reliability and performance of simulated systems. Petri nets have received wide acceptance for modeling complex and highly parallel computers. In this research data flow models for computer systems are investigated. Data flow models can be used to simulate both software and hardware in a uniform manner. Data flow simulation techniques provide the computer systems designer with a CAD environment which enables highly parallel complex systems to be defined, evaluated at all levels and finally implemented in either hardware or software. Inherent in data flow concept is the hierarchical handling of complex systems. In this paper we will describe how data flow can be used to model computer system.

A chemistry and material perspective on lithium redox flow batteries towards high-density electrical energy storage.

PubMed

Zhao, Yu; Ding, Yu; Li, Yutao; Peng, Lele; Byon, Hye Ryung; Goodenough, John B; Yu, Guihua

2015-11-21

Electrical energy storage system such as secondary batteries is the principle power source for portable electronics, electric vehicles and stationary energy storage. As an emerging battery technology, Li-redox flow batteries inherit the advantageous features of modular design of conventional redox flow batteries and high voltage and energy efficiency of Li-ion batteries, showing great promise as efficient electrical energy storage system in transportation, commercial, and residential applications. The chemistry of lithium redox flow batteries with aqueous or non-aqueous electrolyte enables widened electrochemical potential window thus may provide much greater energy density and efficiency than conventional redox flow batteries based on proton chemistry. This Review summarizes the design rationale, fundamentals and characterization of Li-redox flow batteries from a chemistry and material perspective, with particular emphasis on the new chemistries and materials. The latest advances and associated challenges/opportunities are comprehensively discussed.

Geology, Streamflow, and Water Chemistry of the Talufofo Stream Basin, Saipan, Northern Mariana Islands

USGS Publications Warehouse

Izuka, Scot K.; Ewart, Charles J.

1995-01-01

A study of the geology, streamflow, and water chemistry of Talufofo Stream Basin, Saipan, Commonwealth of the Northern Mariana Islands, was undertaken to determine the flow characteristics of Talufofo Stream and the relation to the geology of the drainage basin. The Commonwealth government is exploring the feasibility of using water from Talufofo Stream to supplement Saipan's stressed municipal water supply. Streamflow records from gaging stations on the principal forks of Talufofo Stream indicate that peak streamflows and long-term average flow are higher at the South Fork gaging station than at the Middle Fork gaging station because the drainage area of the South Fork gaging station is larger, but persistent base flow from ground-water discharge during dry weather is greater in the Middle Fork gaging station. The sum of the average flows at the Middle Fork and South Fork gaging stations, plus an estimate of the average flow at a point in the lower reaches of the North Fork, is about 2.96 cubic feet per second or 1.91 million gallons per day. Although this average represents the theoretical maximum long-term draft rate possible from the Talufofo Stream Basin if an adequate reservoir can be built, the actual amount of surface water available will be less because of evaporation, leaks, induced infiltration, and reservoir-design constraints. Base-flow characteristics, such as stream seepage and spring discharge, are related to geology of the basin. Base flow in the Talufofo Stream Basin originates as discharge from springs near the base of limestones located in the headwaters of Talufofo Stream, flows over low-permeability volcanic rocks in the middle reaches, and seeps back into the high-permeability limestones in the lower reaches. Water sampled from Talufofo Stream during base flow had high dissolved-calcium concentrations (between 35 and 98 milligrams per liter), characteristic of water from a limestone aquifer. Concentrations of potassium, sodium, and chloride ions in water samples from Talufofo Stream are characteristic of water draining a heavily vegetated basin near the ocean. The streamflow and water-chemistry data indicate that discharge from springs is in hydraulic connection with the limestone aquifer near the headwaters of the basin. The base flow therefore is subject to stresses placed on the nearby limestone ground-water system. Pumping from wells in the limestones at the headwaters of Talufofo Stream Basin may decrease spring flow in Talufofo Stream.

Review of Fluorescence-Based Velocimetry Techniques to Study High-Speed Compressible Flows

NASA Technical Reports Server (NTRS)

Bathel, Brett F.; Johansen, Criag; Inman, Jennifer A.; Jones, Stephen B.; Danehy, Paul M.

2013-01-01

This paper reviews five laser-induced fluorescence-based velocimetry techniques that have been used to study high-speed compressible flows at NASA Langley Research Center. The techniques discussed in this paper include nitric oxide (NO) molecular tagging velocimetry (MTV), nitrogen dioxide photodissociation (NO2-to-NO) MTV, and NO and atomic oxygen (O-atom) Doppler-shift-based velocimetry. Measurements of both single-component and two-component velocity have been performed using these techniques. This paper details the specific application and experiment for which each technique has been used, the facility in which the experiment was performed, the experimental setup, sample results, and a discussion of the lessons learned from each experiment.

Elongational Flow Assists with the Assembly of Protein Nanofibrils

NASA Astrophysics Data System (ADS)

Mittal, Nitesh; Kamada, Ayaka; Lendel, Christofer; Lundell, Fredrik; Soderberg, Daniel

2016-11-01

Controlling the aggregation process of protein-based macromolecular structures in a confined environment using small-scale flow devices and understanding their assembly mechanisms is essential to develop bio-based materials. Whey protein, a protein mixture with β-lactoglobulin as main component, is able to self-assemble into amyloid-like protein nanofibers which are stabilized by hydrogen bonds. The conditions at which the fibrillation process occurs can affect the properties and morphology of the fibrils. Here, we show that the morphology of protein nanofibers greatly affects their assembly. We used elongational flow based double flow-focusing device for this study. In-situ behavior of the straight and flexible fibrils in the flow channel is determined using small-angle X-ray scattering (SAXS) technique. Our process combines hydrodynamic alignment with dispersion to gel-transition that produces homogeneous and smooth fibers. Moreover, successful alignment before gelation demands a proper separation of the time-scales involved, which we tried to identify in the current study. The presented approach combining small scale flow devices with in-situ synchrotron X-ray studies and protein engineering is a promising route to design high performance protein-based materials with controlled physical and chemical properties. We acknowledge the support from Wallenberg Wood Science Center.

Improving visit cycle time using patient flow analysis in a high-volume inner-city hospital-based ambulatory clinic serving minority New Yorkers.

PubMed

Dhar, Sanjay; Michel, Raquel; Kanna, Balavenkatesh

2011-01-01

Patient waiting time and waiting room congestion are quality indicators that are related to efficiency of ambulatory care systems and patient satisfaction. Our main purpose was to test a program to decrease patient visit cycle time, while maintaining high-quality healthcare in a high-volume inner-city hospital-based clinic in New York City. Use of patient flow analysis and the creation of patient care teams proved useful in identifying areas for improvement, target, and measure effectiveness of interventions. The end result is reduced visit cycle time, improved provider team performance, and sustained patient care outcomes. © 2010 National Association for Healthcare Quality.

A sampling plan for conduit-flow karst springs: Minimizing sampling cost and maximizing statistical utility

USGS Publications Warehouse

Currens, J.C.

1999-01-01

Analytical data for nitrate and triazines from 566 samples collected over a 3-year period at Pleasant Grove Spring, Logan County, KY, were statistically analyzed to determine the minimum data set needed to calculate meaningful yearly averages for a conduit-flow karst spring. Results indicate that a biweekly sampling schedule augmented with bihourly samples from high-flow events will provide meaningful suspended-constituent and dissolved-constituent statistics. Unless collected over an extensive period of time, daily samples may not be representative and may also be autocorrelated. All high-flow events resulting in a significant deflection of a constituent from base-line concentrations should be sampled. Either the geometric mean or the flow-weighted average of the suspended constituents should be used. If automatic samplers are used, then they may be programmed to collect storm samples as frequently as every few minutes to provide details on the arrival time of constituents of interest. However, only samples collected bihourly should be used to calculate averages. By adopting a biweekly sampling schedule augmented with high-flow samples, the need to continuously monitor discharge, or to search for and analyze existing data to develop a statistically valid monitoring plan, is lessened.Analytical data for nitrate and triazines from 566 samples collected over a 3-year period at Pleasant Grove Spring, Logan County, KY, were statistically analyzed to determine the minimum data set needed to calculate meaningful yearly averages for a conduit-flow karst spring. Results indicate that a biweekly sampling schedule augmented with bihourly samples from high-flow events will provide meaningful suspended-constituent and dissolved-constituent statistics. Unless collected over an extensive period of time, daily samples may not be representative and may also be autocorrelated. All high-flow events resulting in a significant deflection of a constituent from base-line concentrations should be sampled. Either the geometric mean or the flow-weighted average of the suspended constituents should be used. If automatic samplers are used, then they may be programmed to collect storm samples as frequently as every few minutes to provide details on the arrival time of constituents of interest. However, only samples collected bihourly should be used to calculate averages. By adopting a biweekly sampling schedule augmented with high-flow samples, the need to continuously monitor discharge, or to search for and analyze existing data to develop a statistically valid monitoring plan, is lessened.

Dissolved oxygen in the Tualatin River, Oregon, during winter flow conditions, 1991 and 1992

USGS Publications Warehouse

Kelly, V.J.

1996-01-01

Throughout the winter period, November through April, wastewater treatment plants in the Tualatin River Basin discharge from 10,000 to 15,000 pounds per day of biochemical oxygen demand to the river. These loads often increase substantially during storms when streamflow is high. During the early winter season, when streamflow is frequently less than the average winter flow, the treatment plants discharge about 2,000 pounds per day of ammonia. This study focused on the capacity of the Tualatin River to assimilat oxygen-demanding loads under winter streamflow conditions during the 1992 water year, with an emphasis on peak-flow conditions in the river, and winter-base-flow conditions during November 1992. Concentrations of dissolved oxygen throughout the main stem of the river during the winter remained generally high relative to the State standard for Oregon of 6 milligrams per liter. The most important factors controlling oxygen consumption during winter-low-flow conditions were carbonaceous biochemical oxygen demand and input of oxygen-depleted waters from tributaries. During peak-flow conditions, reduced travel time and increased dilution associated with the increased streamflow minimized the effect of increased oxygen-demanding loads. During the base-flow period in November 1992, concentrations of dissolved oxygen were consistently below 6 milligrams per liter. A hydrodynamic water-quality model was used to identify the processes depleting dissolved oxygen, including sediment oxygen demand, nitrification, and carbonaceous biochemical oxygen demand. Sediment oxygen demand was the most significant factor; nitrification was also important. Hypothetical scenarios were posed to evaluate the effect of different wastewater treatment plant loads during winter-base-flow conditions. Streamflow and temperature were significant factors governing concentrations of dissolved oxygen in the main-stem river.

The characterisation and application of a pulsed neodymium YAG laser DGV system to a time-varying high-speed flow

NASA Astrophysics Data System (ADS)

Thorpe, S. J.; Quinlan, N.; Ainsworth, R. W.

2000-10-01

Doppler Global Velocimetry (DGV) is a whole-field measurement technique which has attracted significant interest from the fluid-flow research community since its introduction in 1991. Practical implementations of the methodology have focused on two principal laser light sources: the argon ion laser, applied to steady state or slowly varying flows; and the pulsed neodymium YAG laser for the measurement of instantaneous velocity fields. However, the emphasis in the published literature has been very much on research using the argon laser. This paper reports the application of a Q-switched, injection-seeded neodymium YAG laser to the proven Oxford DGV system, and the use of this combination in a short duration unsteady high-speed flow. The pertinent characteristics of the apparatus are described, and the impact of these on the integrity of the resulting velocity measurements is presented. Adaptations to the commercial laser system that make it suitable for application to the measurement of transient high-speed flows are described. Finally, the application of this system to a short duration unsteady flow is described. This application is based on the flow found in a new type of transdermal drug delivery device, where particles of the drug material are projected at high speed through the skin. Whole-field velocities are recorded, and values as high as 800 m/ s are evident.

Hemodynamic Study of Flow Remodeling Stent Graft for the Treatment of Highly Angulated Abdominal Aortic Aneurysm

PubMed Central

Yeow, Siang Lin; Leo, Hwa Liang

2016-01-01

This study investigates the effect of a novel flow remodeling stent graft (FRSG) on the hemodynamic characteristics in highly angulated abdominal aortic aneurysm based on computational fluid dynamics (CFD) approach. An idealized aortic aneurysm with varying aortic neck angulations was constructed and CFD simulations were performed on nonstented models and stented models with FRSG. The influence of FRSG intervention on the hemodynamic performance is analyzed and compared in terms of flow patterns, wall shear stress (WSS), and pressure distribution in the aneurysm. The findings showed that aortic neck angulations significantly influence the velocity flow field in nonstented models, with larger angulations shifting the mainstream blood flow towards the center of the aorta. By introducing FRSG treatment into the aneurysm, erratic flow recirculation pattern in the aneurysm sac diminishes while the average velocity magnitude in the aneurysm sac was reduced in the range of 39% to 53%. FRSG intervention protects the aneurysm against the impacts of high velocity concentrated flow and decreases wall shear stress by more than 50%. The simulation results highlighted that FRSG may effectively treat aneurysm with high aortic neck angulations via the mechanism of promoting thrombus formation and subsequently led to the resorption of the aneurysm. PMID:27247612

Dynamics of Active Separation Control at High Reynolds Numbers

NASA Technical Reports Server (NTRS)

Pack, LaTunia G.; Seifert, Avi

2000-01-01

A series of active flow control experiments were recently conducted at high Reynolds numbers on a generic separated configuration. The model simulates the upper surface of a 20% thick Glauert-Goldschmied type airfoil at zero angle of attack. The flow is fully turbulent since the tunnel sidewall boundary layer flows over the model. The main motivation for the experiments is to generate a comprehensive data base for validation of unsteady numerical simulation as a first step in the development of a CFD design tool, without which it would not be possible to effectively utilize the great potential of unsteady flow control. This paper focuses on the dynamics of several key features of the baseline as well as the controlled flow. It was found that the thickness of the upstream boundary layer has a negligible effect on the flow dynamics. It is speculated that separation is caused mainly by the highly convex surface while viscous effects are less important. The two-dimensional separated flow contains unsteady waves centered on a reduced frequency of 0.8, while in the three dimensional separated flow, frequencies around a reduced frequency of 0.3 and 1 are active. Several scenarios of resonant wave interaction take place at the separated shear-layer and in the pressure recovery region. The unstable reduced frequency bands for periodic excitation are centered on 1.5 and 5, but these reduced frequencies are based on the length of the baseline bubble that shortens due to the excitation. The conventional swept wing-scaling works well for the coherent wave features. Reproduction of these dynamic effects by a numerical simulation would provide benchmark validation.

Study the effect of nitrogen flow rate on tribological properties of tantalum nitride based coatings

NASA Astrophysics Data System (ADS)

Chauhan, Dharmesh B.; Chauhan, Kamlesh V.; Sonera, Akshay L.; Makwana, Nishant S.; Dave, Divyeshkumar P.; Rawal, Sushant K.

2018-05-01

Tantalum Nitride (TaN) based coatings are well-known for their high temperature stability and chemical inertness. We have studied the effect of nitrogen flow rate variation on the structural and tribological properties of TaN based coating deposited by RF magnetron sputtering process. The nitrogen flow rate was varied from 5 to 30 sccm. X-ray diffractometer (XRD) and Atomic Force Microscopy (AFM) were used to determine structure and surface topography of coating. Pin on disc tribometer was used to determine tribological properties of coating. TaN coated brass and mild steel substrates shows higher wear resistance compared to uncoated substrates of brass and mild steel.

Development and application of a particle image velocimeter for high-speed flows

NASA Astrophysics Data System (ADS)

Molezzi, M. J.; Dutton, J. C.

1992-01-01

A particle image velocimetry (PIV) system has been developed for use in high-speed separated air flows. The image acquisition system uses two 550 mJ/pulse Nd:YAG lasers and is fully controlled by a host Macintosh computer. The interrogation system is also Macintosh-based and performs interrogations at approximately 2.3 sec/spot and 4.0 sec/spot when using the Young's fringe and autocorrelation methods, respectively. The system has been proven in preliminary experiments using known-displacement simulated PIV photographs and a simple axisymmetric jet flow. Further results have been obtained in a transonic wind tunnel operating at Mach 0.4 to 0.5 (135 m/s to 170 m/s). PIV experiments were done with an empty test section to provide uniform flow data for comparison with pressure and LDV data, then with a two-dimensional base model, revealing features of the von Karman vortex street wake and underlying small scale turbulence.

Robust optical flow using adaptive Lorentzian filter for image reconstruction under noisy condition

NASA Astrophysics Data System (ADS)

Kesrarat, Darun; Patanavijit, Vorapoj

2017-02-01

In optical flow for motion allocation, the efficient result in Motion Vector (MV) is an important issue. Several noisy conditions may cause the unreliable result in optical flow algorithms. We discover that many classical optical flows algorithms perform better result under noisy condition when combined with modern optimized model. This paper introduces effective robust models of optical flow by using Robust high reliability spatial based optical flow algorithms using the adaptive Lorentzian norm influence function in computation on simple spatial temporal optical flows algorithm. Experiment on our proposed models confirm better noise tolerance in optical flow's MV under noisy condition when they are applied over simple spatial temporal optical flow algorithms as a filtering model in simple frame-to-frame correlation technique. We illustrate the performance of our models by performing an experiment on several typical sequences with differences in movement speed of foreground and background where the experiment sequences are contaminated by the additive white Gaussian noise (AWGN) at different noise decibels (dB). This paper shows very high effectiveness of noise tolerance models that they are indicated by peak signal to noise ratio (PSNR).

Vortical Flow Prediction Using an Adaptive Unstructured Grid Method

NASA Technical Reports Server (NTRS)

Pirzadeh, Shahyar Z.

2001-01-01

A computational fluid dynamics (CFD) method has been employed to compute vortical flows around slender wing/body configurations. The emphasis of the paper is on the effectiveness of an adaptive grid procedure in "capturing" concentrated vortices generated at sharp edges or flow separation lines of lifting surfaces flying at high angles of attack. The method is based on a tetrahedral unstructured grid technology developed at the NASA Langley Research Center. Two steady-state, subsonic, inviscid and Navier-Stokes flow test cases are presented to demonstrate the applicability of the method for solving practical vortical flow problems. The first test case concerns vortex flow over a simple 65deg delta wing with different values of leading-edge bluntness, and the second case is that of a more complex fighter configuration. The superiority of the adapted solutions in capturing the vortex flow structure over the conventional unadapted results is demonstrated by comparisons with the windtunnel experimental data. The study shows that numerical prediction of vortical flows is highly sensitive to the local grid resolution and that the implementation of grid adaptation is essential when applying CFD methods to such complicated flow problems.

The three-dimensional flow past a rapidly rotating circular cylinder

NASA Technical Reports Server (NTRS)

Denier, James P.; Duck, Peter W.

1993-01-01

The high Reynolds number (Re) flow past a rapidly rotating circular cylinder is investigated. The rotation rate of the cylinder is allowed to vary (slightly) along the axis of the cylinder, thereby provoking three-dimensional flow disturbances, which are shown to involve relatively massive (O(Re)) velocity perturbations to the flow away from the cylinder surface. Additionally, three integral conditions, analogous to the single condition determined in two dimensions by Batchelor, are derived, based on the condition of periodicity in the azimuthal direction.

Computation of Incompressible Potential Flow over an Airfoil Using a High Order Aerodynamic Panel Method Based on Circular Arc Panels.

DTIC Science & Technology

1982-08-01

Vortex Sheet Figure 4 - Properties of Singularity Sheets they may be used to model different types of flow. Transfer of boundary... Vortex Sheet Equivalence Singularity Behavior Using Green’s theorem it is clear that the problem of potential flow over a body can be modeled using ...that source, doublet, or vortex singularities can be used to model potential flow problems, and that the doublet and vortex singularities are

Heat transfer measurements on biconics at incidence in hypersonic high enthalpy air and nitrogen flows

NASA Technical Reports Server (NTRS)

Gai, S. L.; Cain, T.; Joe, W. S.; Sandeman, R. J.; Miller, C. G.

1988-01-01

Heat transfer rate measurements have been obtained at 0, 5, 15, and 21 deg angles-of-attack for a straight biconic scale model of an aeroassisted orbital vehicle proposed for planetary probe missions. Heat-transfer distributions were measured using palladium thin-film resistance gauges deposited on a glass-ceramic substrate. The windward heat transfer correlations were based on equilibrium flow in the shock layer of the model, although the flow may depart from equilibrium in the flow-field.

Speckle contrast diffuse correlation tomography of complex turbid medium flow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Huang, Chong; Irwin, Daniel; Lin, Yu

2015-07-15

Purpose: Developed herein is a three-dimensional (3D) flow contrast imaging system leveraging advancements in the extension of laser speckle contrast imaging theories to deep tissues along with our recently developed finite-element diffuse correlation tomography (DCT) reconstruction scheme. This technique, termed speckle contrast diffuse correlation tomography (scDCT), enables incorporation of complex optical property heterogeneities and sample boundaries. When combined with a reflectance-based design, this system facilitates a rapid segue into flow contrast imaging of larger, in vivo applications such as humans. Methods: A highly sensitive CCD camera was integrated into a reflectance-based optical system. Four long-coherence laser source positions were coupledmore » to an optical switch for sequencing of tomographic data acquisition providing multiple projections through the sample. This system was investigated through incorporation of liquid and solid tissue-like phantoms exhibiting optical properties and flow characteristics typical of human tissues. Computer simulations were also performed for comparisons. A uniquely encountered smear correction algorithm was employed to correct point-source illumination contributions during image capture with the frame-transfer CCD and reflectance setup. Results: Measurements with scDCT on a homogeneous liquid phantom showed that speckle contrast-based deep flow indices were within 12% of those from standard DCT. Inclusion of a solid phantom submerged below the liquid phantom surface allowed for heterogeneity detection and validation. The heterogeneity was identified successfully by reconstructed 3D flow contrast tomography with scDCT. The heterogeneity center and dimensions and averaged relative flow (within 3%) and localization were in agreement with actuality and computer simulations, respectively. Conclusions: A custom cost-effective CCD-based reflectance 3D flow imaging system demonstrated rapid acquisition of dense boundary data and, with further studies, a high potential for translatability to real tissues with arbitrary boundaries. A requisite correction was also found for measurements in the fashion of scDCT to recover accurate speckle contrast of deep tissues.« less

Pre-Darcy Flow in Porous Media

NASA Astrophysics Data System (ADS)

Dejam, Morteza; Hassanzadeh, Hassan; Chen, Zhangxin

2017-10-01

Fluid flow in porous media is very important in a wide range of science and engineering applications. The entire establishment of fluid flow application in porous media is based on the use of an experimental law proposed by Darcy (1856). There are evidences in the literature that the flow of a fluid in consolidated and unconsolidated porous media does not follow Darcy law at very low fluxes, which is called pre-Darcy flow. In this paper, the unsteady flow regimes of a slightly compressible fluid under the linear and radial pre-Darcy flow conditions are modeled and the corresponding highly nonlinear diffusivity equations are solved analytically by aid of a generalized Boltzmann transformation technique. The influence of pre-Darcy flow on the pressure diffusion for homogeneous porous media is studied in terms of the nonlinear exponent and the threshold pressure gradient. In addition, the pressure gradient, flux, and cumulative production per unit area are compared with the classical solution of the diffusivity equation based on Darcy flow. The presented results advance our understanding of fluid flow in low-permeability media such as shale and tight formations, where pre-Darcy is the dominant flow regime.

A new method for calculating ecological flow: Distribution flow method

NASA Astrophysics Data System (ADS)

Tan, Guangming; Yi, Ran; Chang, Jianbo; Shu, Caiwen; Yin, Zhi; Han, Shasha; Feng, Zhiyong; Lyu, Yiwei

2018-04-01

A distribution flow method (DFM) and its ecological flow index and evaluation grade standard are proposed to study the ecological flow of rivers based on broadening kernel density estimation. The proposed DFM and its ecological flow index and evaluation grade standard are applied into the calculation of ecological flow in the middle reaches of the Yangtze River and compared with traditional calculation method of hydrological ecological flow, method of flow evaluation, and calculation result of fish ecological flow. Results show that the DFM considers the intra- and inter-annual variations in natural runoff, thereby reducing the influence of extreme flow and uneven flow distributions during the year. This method also satisfies the actual runoff demand of river ecosystems, demonstrates superiority over the traditional hydrological methods, and shows a high space-time applicability and application value.

High order spectral difference lattice Boltzmann method for incompressible hydrodynamics

NASA Astrophysics Data System (ADS)

Li, Weidong

2017-09-01

This work presents a lattice Boltzmann equation (LBE) based high order spectral difference method for incompressible flows. In the present method, the spectral difference (SD) method is adopted to discretize the convection and collision term of the LBE to obtain high order (≥3) accuracy. Because the SD scheme represents the solution as cell local polynomials and the solution polynomials have good tensor-product property, the present spectral difference lattice Boltzmann method (SD-LBM) can be implemented on arbitrary unstructured quadrilateral meshes for effective and efficient treatment of complex geometries. Thanks to only first oder PDEs involved in the LBE, no special techniques, such as hybridizable discontinuous Galerkin method (HDG), local discontinuous Galerkin method (LDG) and so on, are needed to discrete diffusion term, and thus, it simplifies the algorithm and implementation of the high order spectral difference method for simulating viscous flows. The proposed SD-LBM is validated with four incompressible flow benchmarks in two-dimensions: (a) the Poiseuille flow driven by a constant body force; (b) the lid-driven cavity flow without singularity at the two top corners-Burggraf flow; and (c) the unsteady Taylor-Green vortex flow; (d) the Blasius boundary-layer flow past a flat plate. Computational results are compared with analytical solutions of these cases and convergence studies of these cases are also given. The designed accuracy of the proposed SD-LBM is clearly verified.

Electrokinetic high pressure hydraulic system

DOEpatents

Paul, Phillip H.; Rakestraw, David J.

2000-01-01

A compact high pressure hydraulic pump having no moving mechanical parts for converting electric potential to hydraulic force. The electrokinetic pump, which can generate hydraulic pressures greater than 2500 psi, can be employed to compress a fluid, either liquid or gas, and manipulate fluid flow. The pump is particularly useful for capillary-base systems. By combining the electrokinetic pump with a housing having chambers separated by a flexible member, fluid flow, including high pressure fluids, is controlled by the application of an electric potential, that can vary with time.

Hydrogeological characterization of flow system in a karstic aquifer, Seymareh dam, Iran

NASA Astrophysics Data System (ADS)

Behrouj Peely, Ahmad; Mohammadi, Zargham; Raeisi, Ezzatollah; Solgi, Khashayar; Mosavi, Mohammad J.; Kamali, Majid

2018-07-01

In order to determine the characteristics of the flow system in a karstic aquifer, an extensive hydrogeological study includes dye tracing test was conducted. The aquifer suited left abutment of Seymareh Dam, in Ravandi Anticline and discharges by more than 50 springs in the southern flank. Flow system in the aquifer is mainly controlled by the reservoir of Seymareh Dam. Time variations of the spring discharge and water table in the observation wells were highly correlated with the reservoir water level. The average groundwater velocity ranges from 0.2 to more than 14 m/h based on the dye tracing test. The probable flow paths were differentiated in two groups including the flow paths in the northern and southern flanks of Ravandi Anticline. Types of groundwater flow in the proposed flow paths are determined as diffuse or conduit flow type considering groundwater velocity and shape of the breakthrough curves. An index is proposed for differentiation of diffuse and conduit flow system based on relationship of groundwater velocity and hydraulic gradient. Dominant geometry of the flow routs (e.g., conduit diameter and fracture aperture) is estimated for the groundwater flow paths toward the springs. Based on velocity variations and variance coefficient of the water table and discharge of springs on map view a major karst conduit was probably developed in the aquifer. This research emphasizes applying of an extensive hydrogeological study for characterization of flow system in the karst aquifer.

IR-thermography-based investigation of critical heat flux in subcooled flow boiling of water at atmospheric and high pressure conditions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bucci, Matteo; Seong, Jee H.; Buongiorno, Jdacopo

Here we report on MIT’s THM work in Q4 2016 and Q1 2017. The goal of this project is to design, construct and execute tests of flow boiling critical heat flux (CHF) at high-pressure using high-resolution and high-speed video and infrared (IR) thermometry, to generate unique data to inform the development of and validate mechanistic boiling heat transfer and CHF models. In FY2016, a new test section was designed and fabricated. Data was collected at atmospheric conditions at 10, 25 and 50 K subcoolings, and three mass fluxes, i.e. 500, 750 and 1000 kg/m2/s. Starting in Q4 2016 and continuingmore » forward, new post-processing techniques have been developed to analyze the data collected. These new algorithms analyze the time-dependent temperature and heat flux distributions to calculate nucleation site density, nucleation frequency, growth and wait time, dry area fraction, and the complete heat flux partitioning. In Q1 2017 a new flow boiling loop was designed and constructed to support flow boiling tests up 10 bar pressure and 180 °C. Initial shakedown and testing has been completed. The flow loop and test section are now ready to begin high-pressure flow boiling testing.« less

Simulation of High-Speed Droplet Impact Against Dry Substrates with Partial Velocity Slip

NASA Astrophysics Data System (ADS)

Kondo, Tomoki; Ando, Keita

2017-11-01

High-speed droplet impact can be used to clean substrates such as silicon wafers. Radially spreading shear flow after the impact may allow for mechanically removing contaminant particles at substrate surfaces. Since it is a big challenge to experimentally explore such complicated flow that exhibits contact line motion and water hammer, its flow feature is not well understood. Here, we aim to numerically evaluate shear flow caused by the impact of a spherical water droplet (of submillimeter sizes) at high speed (up to 50 m/s) against a dry rigid wall. We model the flow based on compressible Navier-Stokes equations with Stokes' hypothesis and solve them by a high-order-accurate finite volume method equipped with shock and interface capturing. To treat the motion of a contact line between the three phases (the droplet, the rigid wall, and the ambient air) in a robust manner, we permit velocity slip at the wall with Navier's model, for wall slip is known to come into play under steep velocity gradients that can arise from high-speed droplet impact. In our presentation, we will examine radially spreading flow after the droplet impact and the resulting wall shear stress generation from the simulation. This work was supported by JSPS KAKENHI Grant Number JP17J02211.

The effect of inflation on the morphology-derived rheological parameters of lava flows and its implications for interpreting remote sensing data - A case study on the 2014/2015 eruption at Holuhraun, Iceland

NASA Astrophysics Data System (ADS)

Kolzenburg, S.; Jaenicke, J.; Münzer, U.; Dingwell, D. B.

2018-05-01

Morphology-derived lava flow rheology is a frequently used tool in volcanology and planetary science to determine rheological parameters and deduce the composition of lavas on terrestrial planets and their moons. These calculations are usually based on physical equations incorporating 1) lava flow driving forces: gravity, slope and flow-rate and 2) morphological data such as lava flow geometry: flow-width, -height or shape of the flow outline. All available methods assume that no geometrical changes occur after emplacement and that the measured flow geometry reflects the lava's apparent viscosity and/or yield strength during emplacement. It is however well-established from terrestrial examples that lava flows may inflate significantly after the cessation of flow advance. This inflation affects, in turn, the width-to-height ratio upon which the rheological estimates are based and thus must result in uncertainties in the determination of flow rheology, as the flow height is one of the key parameters in the morphology-based deduction of flow properties. Previous studies have recognized this issue but, to date, no assessment of the magnitude of this error has been presented. This is likely due to a lack of digital elevation models (DEMs) at sufficiently high spatial and temporal resolution. The 2014/15 Holuhraun eruption in central Iceland represents one of the best monitored large volume (1.5 km3) lava flow fields (85 km2) to date. An abundance of scientific field and remote sensing data were collected during its emplacement. Moreover, inflation plays a key role in the emplacement dynamics of the late stage of the lava field. Here, we use a time series of high resolution DEMs acquired by the TanDEM-X satellite mission prior, during and after the eruption to evaluate the error associated with the most common methods of deriving lava flow rheology from morphological parameters used in planetary science. We can distinguish two dominant processes as sources of error in the determination of lava flow rheology from morphology 1) wholesale inflation of lava channels and 2) post halting inflation of individual lava toes. These result in a 2.4- to 17 - fold overestimation of apparent viscosity and a 0.7- to 2.4 - fold overestimation of yield strength. When applied in planetary sciences, this overestimation in rheological parameters translates directly to an overestimation of the respective lavas silica content. We conclude that, although qualitatively informative, morphological analysis is insufficient to discern lava rheology and composition. Instead, in-situ analysis together with high resolution remote sensing data is needed to properly constrain the compositions involved in planetary volcanism.

Trends in Flow-based Biosensing Systems for Pesticide Assessment

PubMed Central

Prieto-Simón, Beatriz; Campàs, Mònica; Andreescu, Silvana; Marty, Jean-Louis

2006-01-01

This review gives a survey on the state of the art of pesticide detection using flow-based biosensing systems for sample screening. Although immunosensor systems have been proposed as powerful pesticide monitoring tools, this review is mainly focused on enzyme-based biosensors, as they are the most commonly employed when using a flow system. Among the different detection methods able to be integrated into flow-injection analysis (FIA) systems, the electrochemical ones will be treated in more detail, due to their high sensitivity, simple sample pretreatment, easy operational procedures and real-time detection. During the last decade, new trends have been emerging in order to increase the enzyme stability, the sensitivity and selectivity of the measurements, and to lower the detection limits. These approaches are based on (i) the design of novel matrices for enzyme immobilisation, (ii) new manifold configurations of the FIA system, sometimes including miniaturisation or lab-on-chip protocols thanks to micromachining technology, (iii) the use of cholinesterase enzymes either from various commercial sources or genetically modified with the aim of being more sensitive, (iv) the incorporation of other highly specific enzymes, such as organophosphate hydrolase (OPH) or parathion hydrolase (PH) and (v) the combination of different electrochemical methods of detection. This article discusses these novel strategies and their advantages and limitations.

Eruption and emplacement dynamics of a thick trachytic lava flow of the Sancy volcano (France)

NASA Astrophysics Data System (ADS)

Latutrie, Benjamin; Harris, Andrew; Médard, Etienne; Gurioli, Lucia

2017-01-01

A 70-m-thick, 2200-m-long (51 × 106 m3) trachytic lava flow unit underlies the Puy de Cliergue (Mt. Dore, France). Excellent exposure along a 400-m-long and 60- to 85-m-high section allows the flow interior to be accessed on two sides of a glacial valley that cuts through the unit. We completed an integrated morphological, structural, textural, and chemical analysis of the unit to gain insights into eruption and flow processes during emplacement of this thick silicic lava flow, so as to elucidate the chamber and flow dynamic processed that operate during the emplacement of such systems. The unit is characterized by an inverse chemical stratification, where there is primitive lava beneath the evolved lava. The interior is plug dominated with a thin basal shear zone overlying a thick basal breccia, with ramping affecting the entire flow thickness. To understand these characteristics, we propose an eruption model that first involves processes operating in the magma chamber whereby a primitive melt is injected into an evolved magma to create a mixed zone at the chamber base. The eruption triggered by this event first emplaced a trachytic dome, into which banded lava from the chamber base was injected. Subsequent endogenous dome growth led to flow down the shallow slope to the east on which the highly viscous (1012 Pa s) coulée was emplaced. The flow likely moved extremely slowly, being emplaced over a period of 4-10 years in a glacial manner, where a thick (>60-m) plug slid over a thin (5-m-thick) basal shear zone. Excellent exposure means that the Puy de Cliergue complex can be viewed as a case type location for understanding and defining the eruption and emplacement of thick, high-viscosity, silicic lava flow systems.

Large Eddy Simulation of High Reynolds Number Complex Flows

NASA Astrophysics Data System (ADS)

Verma, Aman

Marine configurations are subject to a variety of complex hydrodynamic phenomena affecting the overall performance of the vessel. The turbulent flow affects the hydrodynamic drag, propulsor performance and structural integrity, control-surface effectiveness, and acoustic signature of the marine vessel. Due to advances in massively parallel computers and numerical techniques, an unsteady numerical simulation methodology such as Large Eddy Simulation (LES) is well suited to study such complex turbulent flows whose Reynolds numbers (Re) are typically on the order of 10. 6. LES also promises increasedaccuracy over RANS based methods in predicting unsteady phenomena such as cavitation and noise production. This dissertation develops the capability to enable LES of high Re flows in complex geometries (e.g. a marine vessel) on unstructured grids and provide physical insight into the turbulent flow. LES is performed to investigate the geometry induced separated flow past a marine propeller attached to a hull, in an off-design condition called crashback. LES shows good quantitative agreement with experiments and provides a physical mechanism to explain the increase in side-force on the propeller blades below an advance ratio of J=-0.7. Fundamental developments in the dynamic subgrid-scale model for LES are pursued to improve the LES predictions, especially for complex flows on unstructured grids. A dynamic procedure is proposed to estimate a Lagrangian time scale based on a surrogate correlation without any adjustable parameter. The proposed model is applied to turbulent channel, cylinder and marine propeller flows and predicts improved results over other model variants due to a physically consistent Lagrangian time scale. A wall model is proposed for application to LES of high Reynolds number wall-bounded flows. The wall model is formulated as the minimization of a generalized constraint in the dynamic model for LES and applied to LES of turbulent channel flow at various Reynolds numbers up to Reτ=10000 and coarse grid resolutions to obtain significant improvement.

Solution of the Euler equations with viscous-inviscid interaction for high Reynolds number transonic flow past wing/body configurations

NASA Technical Reports Server (NTRS)

Koenig, Keith

1986-01-01

The theoretical and numerical bases of a program for the solution of the Euler equations with viscous-inviscid interaction for high Reynolds number transonic flow past wing/body configurations are explained. The emphasis is upon the logic behind the equation development. The program is fully detailed so that the user can quickly become familiar with its operation.

Enhanced H-filter based on Fåhræus-Lindqvist effect for efficient and robust dialysis without membrane

PubMed Central

Zheng, Wei-Chao; Xie, Rui; He, Li-Qun; Xi, Yue-Heng; Liu, Ying-Mei; Meng, Zhi-Jun; Wang, Wei; Ju, Xiao-Jie; Chen, Gang; Chu, Liang-Yin

2015-01-01

A novel microfluidic device for highly efficient and robust dialysis without membrane is highly desired for the development of portable or wearable microdialyzer. Here we report an enhanced H-filter with pillar array based on Fåhræus-Lindqvist effect (F-L effect) for highly efficient and robust membraneless dialysis of simplified blood for the first time. The H-filter employs two fluids laminarly flowing in the microchannel for continuously membraneless dialysis. With pillar array in the microchannel, the two laminar flows, with one containing blood cells and small molecules and another containing dialyzate solution, can form a cell-free layer at the interface as selective zones for separation. This provides enhanced mixing yet extremely low shear for extraction of small molecules from the blood-cell-containing flow into the dialyzate flow, resulting in robust separation with reduced cell loss and improved efficiency. We demonstrate this by first using Chlorella pyrenoidosa as model cells to quantitatively study the separation performances, and then using simplified human blood for dialysis. The advanced H-filter, with highly efficient and robust performance for membraneless dialysis, shows great potential as promising candidate for rapid blood analysis/separation, and as fundamental structure for portable dialyzer. PMID:26339313

Enhanced H-filter based on Fåhræus-Lindqvist effect for efficient and robust dialysis without membrane.

PubMed

Zheng, Wei-Chao; Xie, Rui; He, Li-Qun; Xi, Yue-Heng; Liu, Ying-Mei; Meng, Zhi-Jun; Wang, Wei; Ju, Xiao-Jie; Chen, Gang; Chu, Liang-Yin

2015-07-01

A novel microfluidic device for highly efficient and robust dialysis without membrane is highly desired for the development of portable or wearable microdialyzer. Here we report an enhanced H-filter with pillar array based on Fåhræus-Lindqvist effect (F-L effect) for highly efficient and robust membraneless dialysis of simplified blood for the first time. The H-filter employs two fluids laminarly flowing in the microchannel for continuously membraneless dialysis. With pillar array in the microchannel, the two laminar flows, with one containing blood cells and small molecules and another containing dialyzate solution, can form a cell-free layer at the interface as selective zones for separation. This provides enhanced mixing yet extremely low shear for extraction of small molecules from the blood-cell-containing flow into the dialyzate flow, resulting in robust separation with reduced cell loss and improved efficiency. We demonstrate this by first using Chlorella pyrenoidosa as model cells to quantitatively study the separation performances, and then using simplified human blood for dialysis. The advanced H-filter, with highly efficient and robust performance for membraneless dialysis, shows great potential as promising candidate for rapid blood analysis/separation, and as fundamental structure for portable dialyzer.

Development of a J-T Micro Compressor

NASA Astrophysics Data System (ADS)

Champagne, P.; Olson, J. R.; Nast, T.; Roth, E.; Collaco, A.; Kaldas, G.; Saito, E.; Loung, V.

2015-12-01

Lockheed Martin has developed and tested a space-quality compressor capable of delivering closed-loop gas flow with a high pressure ratio, suitable for driving a Joule- Thomson cold head. The compressor is based on a traditional “Oxford style” dual-opposed piston compressor with linear drive motors and flexure-bearing clearance-seal technology for high reliability and long life. This J-T compressor retains the approximate size, weight, and cost of the ultra-compact, 200 gram Lockheed Martin Pulse Tube Micro Compressor, despite the addition of a flow-rectifying system to convert the AC pressure wave into a steady flow.

Experimental Investigation of Droplet Evaporation of Water with Ground Admixtures while Motion in a Flame of Liquid Fuel

NASA Astrophysics Data System (ADS)

Dmitriyenko, Margarita A.; Nyashina, Galina S.; Zhdanova, Alena O.; Vysokomornaya, Olga V.

2016-02-01

The evaporation features for the atomized flow of suspension on the base of water with ground admixtures in an area of high-temperature combustion products of liquid flammable substance (acetone) were investigated experimentally by the optical methods of gas flow diagnostic and the high-speed video recording. The scales of influence of clay and silt concentration in droplets of atomized flow on the intensity of its evaporation were determined. The approximation dependences describing a decrease in typical size of suspension droplets at various values of ground admixtures were obtained.

Analytical method for predicting the pressure distribution about a nacelle at transonic speeds

NASA Technical Reports Server (NTRS)

Keith, J. S.; Ferguson, D. R.; Merkle, C. L.; Heck, P. H.; Lahti, D. J.

1973-01-01

The formulation and development of a computer analysis for the calculation of streamlines and pressure distributions around two-dimensional (planar and axisymmetric) isolated nacelles at transonic speeds are described. The computerized flow field analysis is designed to predict the transonic flow around long and short high-bypass-ratio fan duct nacelles with inlet flows and with exhaust flows having appropriate aerothermodynamic properties. The flow field boundaries are located as far upstream and downstream as necessary to obtain minimum disturbances at the boundary. The far-field lateral flow field boundary is analytically defined to exactly represent free-flight conditions or solid wind tunnel wall effects. The inviscid solution technique is based on a Streamtube Curvature Analysis. The computer program utilizes an automatic grid refinement procedure and solves the flow field equations with a matrix relaxation technique. The boundary layer displacement effects and the onset of turbulent separation are included, based on the compressible turbulent boundary layer solution method of Stratford and Beavers and on the turbulent separation prediction method of Stratford.

Navigating the flow: individual and continuum models for homing in flowing environments

PubMed Central

Painter, Kevin J.; Hillen, Thomas

2015-01-01

Navigation for aquatic and airborne species often takes place in the face of complicated flows, from persistent currents to highly unpredictable storms. Hydrodynamic models are capable of simulating flow dynamics and provide the impetus for much individual-based modelling, in which particle-sized individuals are immersed into a flowing medium. These models yield insights on the impact of currents on population distributions from fish eggs to large organisms, yet their computational demands and intractability reduce their capacity to generate the broader, less parameter-specific, insights allowed by traditional continuous approaches. In this paper, we formulate an individual-based model for navigation within a flowing field and apply scaling to derive its corresponding macroscopic and continuous model. We apply it to various movement classes, from drifters that simply go with the flow to navigators that respond to environmental orienteering cues. The utility of the model is demonstrated via its application to ‘homing’ problems and, in particular, the navigation of the marine green turtle Chelonia mydas to Ascension Island. PMID:26538557

Temporal and spatial evolution characteristics of gas-liquid two-phase flow pattern based on image texture spectrum descriptor

NASA Astrophysics Data System (ADS)

Zhou, Xi-Guo; Jin, Ning-De; Wang, Zhen-Ya; Zhang, Wen-Yin

2009-11-01

The dynamic image information of typical gas-liquid two-phase flow patterns in vertical upward pipe is captured by a highspeed dynamic camera. The texture spectrum descriptor is used to describe the texture characteristics of the processed images whose content is represented in the form of texture spectrum histogram, and four time-varying characteristic parameter indexes which represent image texture structure of different flow patterns are extracted. The study results show that the amplitude fluctuation of texture characteristic parameter indexes of bubble flow is lowest and shows very random complex dynamic behavior; the amplitude fluctuation of slug flow is higher and shows intermittent motion behavior between gas slug and liquid slug, and the amplitude fluctuation of churn flow is the highest and shows better periodicity; the amplitude fluctuation of bubble-slug flow is from low to high and oscillating frequence is higher than that of slug flow, and includes the features of both slug flow and bubble flow; the slug-churn flow loses the periodicity of slug flow and churn flow, and the amplitude fluctuation is high. The results indicate that the image texture characteristic parameter indexes of different flow pattern can reflect the flow characteristics of gas-liquid two-phase flow, which provides a new approach to understand the temporal and spatial evolution of flow pattern dynamics.

Long-Term Patterns in C-Q Relations in an Adirondack Stream Reveal Decreasing Severity of Episodic Acidification

NASA Astrophysics Data System (ADS)

Burns, D. A.; Lawrence, G. B.; Driscoll, C. T.; Sullivan, T. J.; Shao, S.; McDonnell, T. C.

2017-12-01

Episodic acidification occurs when surface water pH and ANC decrease temporarily during rain events and snowmelt. The principal drivers of episodic acidification are increases in sulfuric acid, nitric acid, organic acids, and dilution of base cations. In regions where surface waters are sensitive to acid deposition, ANC values may approach or decline below 0 µeq/L during high flows, which may result in deleterious effects to sensitive aquatic biota. The Adirondack Mountains of New York have abundant streams and lakes, many of which are highly sensitive to the effects of acid deposition. Long-term monitoring data indicate that pH and ANC in regional surface waters are increasing in response to decreases in the acidity of atmospheric deposition that result from decreasing SO2 and NOx emissions as the Clean Air Act and its ancillary rules and amendments have been implemented. Most surface-water monitoring focuses on low-flow and broad seasonal patterns, and less is known about how episodic acidification has responded to emissions decreases. Here, we report on spatial and temporal patterns in episodic acidification through analysis of C-Q relations from surveys that target varying flow conditions as well as data from a few long-term intensively sampled stream monitoring sites. Each stream sample was assigned a Q percentile value based on a resident or nearby gage, and a statistical relation between ANC values and Q percentile was developed. The magnitude of episodic decreases in ANC increases as low-flow ANC increases, a pattern that likely results from an increasing influence of dilution, especially evident when low-flow ANC values exceed 100 µeq/L. Chronically acidic streams with low-flow ANC near 0 µeq/L show little episodic acidification, whereas streams with low-flow ANC values of about 50 µeq/L generally show ANC decreases to less than 0 µeq/L at high flow. Preliminary analysis of a 24-yr data set (1991-2014) at Buck Creek indicates that increases in high-flow ANC are more than twice those of low-flow ANC. These ANC values generally no longer decline below 0 µeq/L at the highest flows, which typically occur during spring snowmelt. Further analyses will explore how the drivers of episodic acidification vary across the region with low-flow ANC and whether clear trends in these drivers are evident across the region.

Overview of High-Fidelity Modeling Activities in the Numerical Propulsion System Simulations (NPSS) Project

NASA Technical Reports Server (NTRS)

Veres, Joseph P.

2002-01-01

A high-fidelity simulation of a commercial turbofan engine has been created as part of the Numerical Propulsion System Simulation Project. The high-fidelity computer simulation utilizes computer models that were developed at NASA Glenn Research Center in cooperation with turbofan engine manufacturers. The average-passage (APNASA) Navier-Stokes based viscous flow computer code is used to simulate the 3D flow in the compressors and turbines of the advanced commercial turbofan engine. The 3D National Combustion Code (NCC) is used to simulate the flow and chemistry in the advanced aircraft combustor. The APNASA turbomachinery code and the NCC combustor code exchange boundary conditions at the interface planes at the combustor inlet and exit. This computer simulation technique can evaluate engine performance at steady operating conditions. The 3D flow models provide detailed knowledge of the airflow within the fan and compressor, the high and low pressure turbines, and the flow and chemistry within the combustor. The models simulate the performance of the engine at operating conditions that include sea level takeoff and the altitude cruise condition.

Measurement of Gas-Liquid Two-Phase Flow in Micro-Pipes by a Capacitance Sensor

PubMed Central

Ji, Haifeng; Li, Huajun; Huang, Zhiyao; Wang, Baoliang; Li, Haiqing

2014-01-01

A capacitance measurement system is developed for the measurement of gas-liquid two-phase flow in glass micro-pipes with inner diameters of 3.96, 2.65 and 1.56 mm, respectively. As a typical flow regime in a micro-pipe two-phase flow system, slug flow is chosen for this investigation. A capacitance sensor is designed and a high-resolution and high-speed capacitance measurement circuit is used to measure the small capacitance signals based on the differential sampling method. The performance and feasibility of the capacitance method are investigated and discussed. The capacitance signal is analyzed, which can reflect the voidage variation of two-phase flow. The gas slug velocity is determined through a cross-correlation technique using two identical capacitance sensors. The simulation and experimental results show that the presented capacitance measurement system is successful. Research work also verifies that the capacitance sensor is an effective method for the measurement of gas liquid two-phase flow parameters in micro-pipes. PMID:25587879

Measurement of gas-liquid two-phase flow in micro-pipes by a capacitance sensor.

PubMed

Ji, Haifeng; Li, Huajun; Huang, Zhiyao; Wang, Baoliang; Li, Haiqing

2014-11-26

A capacitance measurement system is developed for the measurement of gas-liquid two-phase flow in glass micro-pipes with inner diameters of 3.96, 2.65 and 1.56 mm, respectively. As a typical flow regime in a micro-pipe two-phase flow system, slug flow is chosen for this investigation. A capacitance sensor is designed and a high-resolution and high-speed capacitance measurement circuit is used to measure the small capacitance signals based on the differential sampling method. The performance and feasibility of the capacitance method are investigated and discussed. The capacitance signal is analyzed, which can reflect the voidage variation of two-phase flow. The gas slug velocity is determined through a cross-correlation technique using two identical capacitance sensors. The simulation and experimental results show that the presented capacitance measurement system is successful. Research work also verifies that the capacitance sensor is an effective method for the measurement of gas liquid two-phase flow parameters in micro-pipes.

Recent theoretical developments and experimental studies pertinent to vortex flow aerodynamics - With a view towards design

NASA Technical Reports Server (NTRS)

Lamar, J. E.; Luckring, J. M.

1978-01-01

A review is presented of recent progress in a research program directed towards the development of an improved vortex-flow technology base. It is pointed out that separation induced vortex-flows from the leading and side edges play an important role in the high angle-of-attack aerodynamic characteristics of a wide range of modern aircraft. In the analysis and design of high-speed aircraft, a detailed knowledge of this type of separation is required, particularly with regard to critical wind loads and the stability and performance at various off-design conditions. A description of analytical methods is presented. The theoretical methods employed are divided into two classes which are dependent upon the underlying aerodynamic assumptions. One conical flow method is considered along with three different nonconical flow methods. Comparisons are conducted between the described methods and available aerodynamic data. Attention is also given to a vortex flow drag study and a vortex flow wing design using suction analogy.

Vibration characteristics of an inclined flip-flow screen panel in banana flip-flow screens

NASA Astrophysics Data System (ADS)

Xiong, Xiaoyan; Niu, Linkai; Gu, Chengxiang; Wang, Yinhua

2017-12-01

A banana flip-flow screen is an effective solution for the screening of high-viscosity, high-water and fine materials. As one of the key components, the vibration characteristics of the inclined flip-flow screen panel largely affects the screen performance and the processing capacity. In this paper, a mathematical model for the vibration characteristic of the inclined flip-flow screen panel is proposed based on Catenary theory. The reasonability of Catenary theory in analyzing the vibration characteristic of flip-flow screen panels is verified by a published experiment. Moreover, the effects of the rotation speed of exciters, the incline angle, the slack length and the characteristics of the screen on the vertical deflection, the vertical velocity and the vertical acceleration of the screen panel are investigated parametrically. The results show that the rotation speed of exciters, the incline angle, the slack length and the characteristics of the screen have significant effects on the vibrations of an inclined flip-flow screen panel, and these parameters should be optimized.

Velocity and void distribution in a counter-current two-phase flow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gabriel, S.; Schulenberg, T.; Laurien, E.

2012-07-01

Different flow regimes were investigated in a horizontal channel. Simulating a hot leg injection in case of a loss of coolant accident or flow conditions in reflux condenser mode, the hydraulic jump and partially reversed flow were identified as major constraints for a high amount of entrained water. Trying to simulate the reflux condenser mode, the test section now includes an inclined section connected to a horizontal channel. The channel is 90 mm high and 110 mm wide. Tests were carried out for water and air at ambient pressure and temperature. High speed video-metry was applied to obtain velocities frommore » flow pattern maps of the rising and falling fluid. In the horizontal part of the channel with partially reversed flow the fluid velocities were measured by planar particle image velocimetry. To obtain reliable results for the gaseous phase, this analysis was extended by endoscope measurements. Additionally, a new method based on the optical refraction at the interface between air and water in a back-light was used to obtain time-averaged void fraction. (authors)« less

Evolution of shock-induced pressure on a flat-face/flat-base body and afterbody flow separation

NASA Technical Reports Server (NTRS)

Yoshikawa, K. K.; Wray, A. A.

1982-01-01

The time-dependent, compressible Reynolds-averaged, Navier-Stokes equations are applied to solve an axisymmetric supersonic flow around a flat-face/flat-base body with and without a sting support. Important transient phenomena, not yet well understood, are investigated, and the significance of the present solution to the phenomena is discussed. The phenomena, described in detail, are as follows: the transient formation of the bow and recompression shock waves; the evolution of a pressure buildup due to diffraction of the incident shock wave in the forebody and afterbody regions, including the luminosity accompanying the pressure buildup; the separation of the flow as influenced by pressure buildup; the location of the separation and the reattachment points; and the transient period of the shock-induced base flow. The important influence of the nonsteady (transient) and steady flow on the aerodynamic characteristics, radiative heat transfer, and, thus, on the survivability or safeguard problems for an aircraft fuselage, missile, or planetary entry probe at very high flight speeds is described.

Predicting nitrate discharge dynamics in mesoscale catchments using the lumped StreamGEM model and Bayesian parameter inference

NASA Astrophysics Data System (ADS)

Woodward, Simon James Roy; Wöhling, Thomas; Rode, Michael; Stenger, Roland

2017-09-01

The common practice of infrequent (e.g., monthly) stream water quality sampling for state of the environment monitoring may, when combined with high resolution stream flow data, provide sufficient information to accurately characterise the dominant nutrient transfer pathways and predict annual catchment yields. In the proposed approach, we use the spatially lumped catchment model StreamGEM to predict daily stream flow and nitrate concentration (mg L-1 NO3-N) in four contrasting mesoscale headwater catchments based on four years of daily rainfall, potential evapotranspiration, and stream flow measurements, and monthly or daily nitrate concentrations. Posterior model parameter distributions were estimated using the Markov Chain Monte Carlo sampling code DREAMZS and a log-likelihood function assuming heteroscedastic, t-distributed residuals. Despite high uncertainty in some model parameters, the flow and nitrate calibration data was well reproduced across all catchments (Nash-Sutcliffe efficiency against Log transformed data, NSL, in the range 0.62-0.83 for daily flow and 0.17-0.88 for nitrate concentration). The slight increase in the size of the residuals for a separate validation period was considered acceptable (NSL in the range 0.60-0.89 for daily flow and 0.10-0.74 for nitrate concentration, excluding one data set with limited validation data). Proportions of flow and nitrate discharge attributed to near-surface, fast seasonal groundwater and slow deeper groundwater were consistent with expectations based on catchment geology. The results for the Weida Stream in Thuringia, Germany, using monthly as opposed to daily nitrate data were, for all intents and purposes, identical, suggesting that four years of monthly nitrate sampling provides sufficient information for calibration of the StreamGEM model and prediction of catchment dynamics. This study highlights the remarkable effectiveness of process based, spatially lumped modelling with commonly available monthly stream sample data, to elucidate high resolution catchment function, when appropriate calibration methods are used that correctly handle the inherent uncertainties.

FISHIS: Fluorescence In Situ Hybridization in Suspension and Chromosome Flow Sorting Made Easy

PubMed Central

Giorgi, Debora; Farina, Anna; Grosso, Valentina; Gennaro, Andrea; Ceoloni, Carla; Lucretti, Sergio

2013-01-01

The large size and complex polyploid nature of many genomes has often hampered genomics development, as is the case for several plants of high agronomic value. Isolating single chromosomes or chromosome arms via flow sorting offers a clue to resolve such complexity by focusing sequencing to a discrete and self-consistent part of the whole genome. The occurrence of sufficient differences in the size and or base-pair composition of the individual chromosomes, which is uncommon in plants, is critical for the success of flow sorting. We overcome this limitation by developing a robust method for labeling isolated chromosomes, named Fluorescent In situ Hybridization In suspension (FISHIS). FISHIS employs fluorescently labeled synthetic repetitive DNA probes, which are hybridized, in a wash-less procedure, to chromosomes in suspension following DNA alkaline denaturation. All typical A, B and D genomes of wheat, as well as individual chromosomes from pasta (T. durum L.) and bread (T. aestivum L.) wheat, were flow-sorted, after FISHIS, at high purity. For the first time in eukaryotes, each individual chromosome of a diploid organism, Dasypyrum villosum (L.) Candargy, was flow-sorted regardless of its size or base-pair related content. FISHIS-based chromosome sorting is a powerful and innovative flow cytogenetic tool which can develop new genomic resources from each plant species, where microsatellite DNA probes are available and high quality chromosome suspensions could be produced. The joining of FISHIS labeling and flow sorting with the Next Generation Sequencing methodology will enforce genomics for more species, and by this mightier chromosome approach it will be possible to increase our knowledge about structure, evolution and function of plant genome to be used for crop improvement. It is also anticipated that this technique could contribute to analyze and sort animal chromosomes with peculiar cytogenetic abnormalities, such as copy number variations or cytogenetic aberrations. PMID:23469124

FISHIS: fluorescence in situ hybridization in suspension and chromosome flow sorting made easy.

PubMed

Giorgi, Debora; Farina, Anna; Grosso, Valentina; Gennaro, Andrea; Ceoloni, Carla; Lucretti, Sergio

2013-01-01

The large size and complex polyploid nature of many genomes has often hampered genomics development, as is the case for several plants of high agronomic value. Isolating single chromosomes or chromosome arms via flow sorting offers a clue to resolve such complexity by focusing sequencing to a discrete and self-consistent part of the whole genome. The occurrence of sufficient differences in the size and or base-pair composition of the individual chromosomes, which is uncommon in plants, is critical for the success of flow sorting. We overcome this limitation by developing a robust method for labeling isolated chromosomes, named Fluorescent In situ Hybridization In suspension (FISHIS). FISHIS employs fluorescently labeled synthetic repetitive DNA probes, which are hybridized, in a wash-less procedure, to chromosomes in suspension following DNA alkaline denaturation. All typical A, B and D genomes of wheat, as well as individual chromosomes from pasta (T. durum L.) and bread (T. aestivum L.) wheat, were flow-sorted, after FISHIS, at high purity. For the first time in eukaryotes, each individual chromosome of a diploid organism, Dasypyrum villosum (L.) Candargy, was flow-sorted regardless of its size or base-pair related content. FISHIS-based chromosome sorting is a powerful and innovative flow cytogenetic tool which can develop new genomic resources from each plant species, where microsatellite DNA probes are available and high quality chromosome suspensions could be produced. The joining of FISHIS labeling and flow sorting with the Next Generation Sequencing methodology will enforce genomics for more species, and by this mightier chromosome approach it will be possible to increase our knowledge about structure, evolution and function of plant genome to be used for crop improvement. It is also anticipated that this technique could contribute to analyze and sort animal chromosomes with peculiar cytogenetic abnormalities, such as copy number variations or cytogenetic aberrations.

Base pressure associated with incompressible flow past wedges at high Reynolds numbers

NASA Technical Reports Server (NTRS)

Warpinski, N. R.; Chow, W. L.

1979-01-01

A model is suggested to study the viscid-inviscid interaction associated with steady incompressible flow past wedges of arbitrary angles. It is shown from this analysis that the determination of the nearly constant pressure (base pressure) prevailing within the near wake is really the heart of the problem and this pressure can only be determined from these interactive considerations. The basic free streamline flow field is established through two discrete parameters which should adequately describe the inviscid flow around the body and the wake. The viscous flow processes such as boundary-layer buildup along the wedge surface, jet mixing, recompression, and reattachment which occurs along the region attached to the inviscid flow in the sense of the boundary-layer concept, serve to determine the aforementioned parameters needed for the establishment of the inviscid flow. It is found that the point of reattachment behaves as a saddle point singularity for the system of equations describing the viscous recompression process. Detailed results such as the base pressure, pressure distributions on the wedge surface, and the wake geometry as well as the influence of the characteristic Reynolds number are obtained. Discussion of these results and their comparison with the experimental data are reported.

Slow-moving and far-travelled dense pyroclastic flows during the Peach Spring super-eruption.

PubMed

Roche, O; Buesch, D C; Valentine, G A

2016-03-07

Explosive volcanic super-eruptions of several hundred cubic kilometres or more generate long run-out pyroclastic density currents the dynamics of which are poorly understood and controversial. Deposits of one such event in the southwestern USA, the 18.8 Ma Peach Spring Tuff, were formed by pyroclastic flows that travelled >170 km from the eruptive centre and entrained blocks up to ∼ 70-90 cm diameter from the substrates along the flow paths. Here we combine these data with new experimental results to show that the flow's base had high-particle concentration and relatively modest speeds of ∼ 5-20 m s(-1), fed by an eruption discharging magma at rates up to ∼ 10(7)-10(8) m(3) s(-1) for a minimum of 2.5-10 h. We conclude that sustained high-eruption discharge and long-lived high-pore pressure in dense granular dispersion can be more important than large initial velocity and turbulent transport with dilute suspension in promoting long pyroclastic flow distance.

Modeling dam-break flows using finite volume method on unstructured grid

USDA-ARS?s Scientific Manuscript database

Two-dimensional shallow water models based on unstructured finite volume method and approximate Riemann solvers for computing the intercell fluxes have drawn growing attention because of their robustness, high adaptivity to complicated geometry and ability to simulate flows with mixed regimes and di...

An eigenvalue approach for the automatic scaling of unknowns in model-based reconstructions: Application to real-time phase-contrast flow MRI.

PubMed

Tan, Zhengguo; Hohage, Thorsten; Kalentev, Oleksandr; Joseph, Arun A; Wang, Xiaoqing; Voit, Dirk; Merboldt, K Dietmar; Frahm, Jens

2017-12-01

The purpose of this work is to develop an automatic method for the scaling of unknowns in model-based nonlinear inverse reconstructions and to evaluate its application to real-time phase-contrast (RT-PC) flow magnetic resonance imaging (MRI). Model-based MRI reconstructions of parametric maps which describe a physical or physiological function require the solution of a nonlinear inverse problem, because the list of unknowns in the extended MRI signal equation comprises multiple functional parameters and all coil sensitivity profiles. Iterative solutions therefore rely on an appropriate scaling of unknowns to numerically balance partial derivatives and regularization terms. The scaling of unknowns emerges as a self-adjoint and positive-definite matrix which is expressible by its maximal eigenvalue and solved by power iterations. The proposed method is applied to RT-PC flow MRI based on highly undersampled acquisitions. Experimental validations include numerical phantoms providing ground truth and a wide range of human studies in the ascending aorta, carotid arteries, deep veins during muscular exercise and cerebrospinal fluid during deep respiration. For RT-PC flow MRI, model-based reconstructions with automatic scaling not only offer velocity maps with high spatiotemporal acuity and much reduced phase noise, but also ensure fast convergence as well as accurate and precise velocities for all conditions tested, i.e. for different velocity ranges, vessel sizes and the simultaneous presence of signals with velocity aliasing. In summary, the proposed automatic scaling of unknowns in model-based MRI reconstructions yields quantitatively reliable velocities for RT-PC flow MRI in various experimental scenarios. Copyright © 2017 John Wiley & Sons, Ltd.

Flow visualization for investigating stator losses in a multistage axial compressor

NASA Astrophysics Data System (ADS)

Smith, Natalie R.; Key, Nicole L.

2015-05-01

The methodology and implementation of a powder-paint-based flow visualization technique along with the illuminated flow physics are presented in detail for application in a three-stage axial compressor. While flow visualization often accompanies detailed studies, the turbomachinery literature lacks a comprehensive study which both utilizes flow visualization to interrupt the flow field and explains the intricacies of execution. Lessons learned for obtaining high-quality images of surface flow patterns are discussed in this study. Fluorescent paint is used to provide clear, high-contrast pictures of the recirculation regions on shrouded vane rows. An edge-finding image processing procedure is implemented to provide a quantitative measure of vane-to-vane variability in flow separation, which is approximately 7 % of the suction surface length for Stator 1. Results include images of vane suction side corner separations from all three stages at three loading conditions. Additionally, streakline patterns obtained experimentally are compared with those calculated from computational models. Flow physics associated with vane clocking and increased rotor tip clearance and their implications to stator loss are also investigated with this flow visualization technique. With increased rotor tip clearance, the vane surface flow patterns show a shift to larger separations and more radial flow at the tip. Finally, the effects of instrumentation on the flow field are highlighted.

On the POD based reduced order modeling of high Reynolds flows

NASA Astrophysics Data System (ADS)

Behzad, Fariduddin; Helenbrook, Brian; Ahmadi, Goodarz

2012-11-01

Reduced-order modeling (ROM) of a high Reynolds fluid flow using the proper orthogonal decomposition (POD) was studied. Particular attention was given to incompressible, unsteady flow over a two-dimensional NACA0015 airfoil. The Reynolds number is 105 and the angle of attacked of the airfoil is 12°. For DNS solution, hp-finite element method is employed to drive flow samples from which the POD modes are extracted. Particular attention is paid on two issues. First, the stability of POD-ROM resimulation of the turbulent flow is studied. High Reynolds flow contains a lot of fluctuating modes. So, to reach a certain amount of error, more POD modes are needed and the effect of truncation of POD modes is more important. Second, the role of convergence rate on the results of POD. Due to complexity of the flow, convergence of the governing equations is more difficult and the influences of weak convergence appear in the results of POD-ROM. For each issue, the capability of the POD-ROM is assessed in terms of predictions quality of times upon which the POD model was derived. The results are compared with DNS solution and the accuracy and efficiency of different cases are evaluated.

Effect of cannula shape on aortic wall and flow turbulence: hydrodynamic study during extracorporeal circulation in mock thoracic aorta.

PubMed

Minakawa, Masahito; Fukuda, Ikuo; Yamazaki, Junichi; Fukui, Kozo; Yanaoka, Hideki; Inamura, Takao

2007-12-01

This study was designed to analyze flow pattern, velocity, and strain on the aortic wall of a glass aortic model during extracorporeal circulation, and to elucidate the characteristics of flow pattern in four aortic cannulas. Different patterns of large vortices and helical flow were made by each cannula. The high-velocity flow (0.6 m/s) was observed in end-hole cannula, causing high strain rate tensor (0.3~0.4 without unit) on the aortic arch. In dispersion cannula, a decreased strain rate tensor (less than 0.1) was found on the outer curvature of the aortic arch. In Soft-flow cannula (3M Cardiovascular, Ann Arbor, MI, USA), further decreased flow velocity (0.2 m/s) and strain (less than 0.2) were observed. In Select 3D cannula (Medtronic, Inc., Minneapolis, MN, USA), a high strain (0.4~0.5) was observed along the inner curvature of the aortic arch. In conclusion, end-hole cannula should not be used in atherosclerotic aorta. Particular attention should be paid both for selection of cannulas and cannulation site based on this result.

A hydrometric and geochemical approach to test the transmissivity feedback hypothesis during snowmelt

NASA Astrophysics Data System (ADS)

Kendall, K. A.; Shanley, J. B.; McDonnell, J. J.

1999-07-01

To test the transmissivity feedback hypothesis of runoff generation, surface and subsurface waters were monitored and sampled during the 1996 snowmelt at various topographic positions in a 41 ha forested headwater catchment at Sleepers River, Vermont. Two conditions that promote transmissivity feedback existed in the catchment during the melt period. First, saturated hydraulic conductivity increased toward land surface, from a geometric mean of 3.6 mm h -1 in glacial till to 25.6 mm h -1 in deep soil to 54.0 mm h -1 in shallow soil. Second, groundwater levels rose to within 0.3 m of land surface at all riparian sites and most hillslope sites at peak melt. The importance of transmissivity feedback to streamflow generation was tested at the catchment scale by examination of physical and chemical patterns of groundwater in near-stream (discharge) and hillslope (recharge/lateral flow) zones, and within a geomorphic hollow (convergent flow). The presence of transmissivity feedback was supported by the abrupt increase in streamflow as the water table rose into the surficial, transmissive zone; a flattening of the groundwater level vs. streamflow curve occurred at most sites. This relation had a clockwise hysteresis (higher groundwater level for given discharge on rising limb than at same discharge on falling limb) at riparian sites, suggesting that the riparian zone was the dominant source area during the rising limb of the melt hydrograph. Hysteresis was counterclockwise at hillslope sites, suggesting that hillslope drainage controlled the snowmelt recession. End member mixing analysis using Ca, Mg, Na, dissolved organic carbon (DOC), and Si showed that stream chemistry could be explained as a two-component mixture of groundwater high in base cations and an O-horizon/overland flow water high in DOC. The dominance of shallow flow paths during events was indicated by the high positive correlation of DOC with streamflow ( r2=0.82). Despite the occurrence of transmissivity feedback, hillslope till and soil water were ruled out as end members primarily because their distinctive high-Si composition had little or no effect on streamwater composition. Till water from the geomorphic hollow had a chemistry very close to streamwater base flow, and may represent the base flow end member better than the more concentrated riparian groundwater. During snowmelt, streamwater composition shifted as this base flow was diluted—not by shallow groundwater from the hillslope, but rather by a more surficial O-horizon/overland flow water.

Modeling study of rarefied gas effects on hypersonic reacting stagnation flows

NASA Astrophysics Data System (ADS)

Wang, Zhihui; Bao, Lin

2014-12-01

Recent development of the near space hypersonic sharp leading vehicles has raised a necessity to fast and accurately predict the aeroheating in hypersonic rarefied flows, which challenges our understanding of the aerothermodynamics and aerothermochemistry. The present flow and heat transfer problem involves complex rarefied gas effects and nonequilibrium real gas effects which are beyond the scope of the traditional prediction theory based on the continuum hypothesis and equilibrium assumption. As a typical example, it has been found that the classical Fay-Riddell equation fails to predict the stagnation point heat flux, when the flow is either rarefied or chemical nonequilibrium. In order to design a more general theory covering the rarefied reacting flow cases, an intuitive model is proposed in this paper to describe the nonequilibrium dissociation-recombination flow along the stagnation streamline towards a slightly blunted nose in hypersonic rarefied flows. Some characteristic flow parameters are introduced, and based on these parameters, an explicitly analytical bridging function is established to correct the traditional theory to accurately predict the actual aeroheating performance. It is shown that for a small size nose in medium density flows, the flow at the outer edge of the stagnation point boundary layer could be highly nonequilibrium, and the aeroheating performance is distinguished from that of the big blunt body reentry flows at high altitudes. As a result, when the rarefied gas effects and the nonequilibrium real gas effects are both significant, the classical similarity law could be questionable, and it is inadequate to directly analogize results from the classical blunt body reentry problems to the present new generation sharp-leading vehicles. In addition, the direct simulation Monte Carlo method is also employed to validate the conclusion.

High-speed aerodynamic design of space vehicle and required hypersonic wind tunnel facilities

NASA Astrophysics Data System (ADS)

Sakakibara, Seizou; Hozumi, Kouichi; Soga, Kunio; Nomura, Shigeaki

Problems associated with the aerodynamic design of space vehicles with emphasis of the role of hypersonic wind tunnel facilities in the development of the vehicle are considered. At first, to identify wind tunnel and computational fluid dynamics (CFD) requirements, operational environments are postulated for hypervelocity vehicles. Typical flight corridors are shown with the associated flow density: real gas effects, low density flow, and non-equilibrium flow. Based on an evaluation of these flight regimes and consideration of the operational requirements, the wind tunnel testing requirements for the aerodynamic design are examined. Then, the aerodynamic design logic and optimization techniques to develop and refine the configurations in a traditional phased approach based on the programmatic design of space vehicle are considered. Current design methodology for the determination of aerodynamic characteristics for designing the space vehicle, i.e., (1) ground test data, (2) numerical flow field solutions and (3) flight test data, are also discussed. Based on these considerations and by identifying capabilities and limits of experimental and computational methods, the role of a large conventional hypersonic wind tunnel and the high enthalpy tunnel and the interrelationship of the wind tunnels and CFD methods in actual aerodynamic design and analysis are discussed.

Structured-illumination photoacoustic Doppler flowmetry of axial flow in homogeneous scattering media

NASA Astrophysics Data System (ADS)

Zhang, Ruiying; Yao, Junjie; Maslov, Konstantin I.; Wang, Lihong V.

2013-08-01

We propose a method for photoacoustic flow measurement based on the Doppler effect from a flowing homogeneous medium. Excited by spatially modulated laser pulses, the flowing medium induces a Doppler frequency shift in the received photoacoustic signals. The frequency shift is proportional to the component of the flow speed projected onto the acoustic beam axis, and the sign of the shift reflects the flow direction. Unlike conventional flowmetry, this method does not rely on particle heterogeneity in the medium; thus, it can tolerate extremely high particle density. A red-ink phantom flowing in a tube immersed in water was used to validate the method in both the frequency and time domains. The phantom flow immersed in an intralipid solution was also measured.

Least Squares Shadowing Sensitivity Analysis of Chaotic Flow Around a Two-Dimensional Airfoil

NASA Technical Reports Server (NTRS)

Blonigan, Patrick J.; Wang, Qiqi; Nielsen, Eric J.; Diskin, Boris

2016-01-01

Gradient-based sensitivity analysis has proven to be an enabling technology for many applications, including design of aerospace vehicles. However, conventional sensitivity analysis methods break down when applied to long-time averages of chaotic systems. This breakdown is a serious limitation because many aerospace applications involve physical phenomena that exhibit chaotic dynamics, most notably high-resolution large-eddy and direct numerical simulations of turbulent aerodynamic flows. A recently proposed methodology, Least Squares Shadowing (LSS), avoids this breakdown and advances the state of the art in sensitivity analysis for chaotic flows. The first application of LSS to a chaotic flow simulated with a large-scale computational fluid dynamics solver is presented. The LSS sensitivity computed for this chaotic flow is verified and shown to be accurate, but the computational cost of the current LSS implementation is high.

Aerodynamic Design of a Dual-Flow Mach 7 Hypersonic Inlet System for a Turbine-Based Combined-Cycle Hypersonic Propulsion System

NASA Technical Reports Server (NTRS)

Sanders, Bobby W.; Weir, Lois J.

2008-01-01

A new hypersonic inlet for a turbine-based combined-cycle (TBCC) engine has been designed. This split-flow inlet is designed to provide flow to an over-under propulsion system with turbofan and dual-mode scramjet engines for flight from takeoff to Mach 7. It utilizes a variable-geometry ramp, high-speed cowl lip rotation, and a rotating low-speed cowl that serves as a splitter to divide the flow between the low-speed turbofan and the high-speed scramjet and to isolate the turbofan at high Mach numbers. The low-speed inlet was designed for Mach 4, the maximum mode transition Mach number. Integration of the Mach 4 inlet into the Mach 7 inlet imposed significant constraints on the low-speed inlet design, including a large amount of internal compression. The inlet design was used to develop mechanical designs for two inlet mode transition test models: small-scale (IMX) and large-scale (LIMX) research models. The large-scale model is designed to facilitate multi-phase testing including inlet mode transition and inlet performance assessment, controls development, and integrated systems testing with turbofan and scramjet engines.

Investigating low flow process controls, through complex modelling, in a UK chalk catchment

NASA Astrophysics Data System (ADS)

Lubega Musuuza, Jude; Wagener, Thorsten; Coxon, Gemma; Freer, Jim; Woods, Ross; Howden, Nicholas

2017-04-01

The typical streamflow response of Chalk catchments is dominated by groundwater contributions due the high degree of groundwater recharge through preferential flow pathways. The groundwater store attenuates the precipitation signal, which causes a delay between the corresponding high and low extremes in the precipitation and the stream flow signals. Streamflow responses can therefore be quite out of phase with the precipitation input to a Chalk catchment. Therefore characterising such catchment systems, including modelling approaches, clearly need to reproduce these percolation and groundwater dominated pathways to capture these dominant flow pathways. The simulation of low flow conditions for chalk catchments in numerical models is especially difficult due to the complex interactions between various processes that may not be adequately represented or resolved in the models. Periods of low stream flows are particularly important due to competing water uses in the summer, including agriculture and water supply. In this study we apply and evaluate the physically-based Pennstate Integrated Hydrologic Model (PIHM) to the River Kennet, a sub-catchment of the Thames Basin, to demonstrate how the simulations of a chalk catchment are improved by a physically-based system representation. We also use an ensemble of simulations to investigate the sensitivity of various hydrologic signatures (relevant to low flows and droughts) to the different parameters in the model, thereby inferring the levels of control exerted by the processes that the parameters represent.

Bi-functional effects of lengthening aliphatic chain of phthalimide-based negative redox couple and its non-aqueous flow battery performance at stack cell

NASA Astrophysics Data System (ADS)

Kim, Hyun-seung; Hwang, Seunghae; Kim, Youngjin; Ryu, Ji Heon; Oh, Seung M.; Kim, Ki Jae

2018-04-01

Effects of lengthening an aliphatic chain of a phthalimide-based negative redox couple for non-aqueous flow batteries are examined. The working voltage and solubility of N-butylphthalimide are 0.1 V lower and four times greater (2.0 M) than those of methyl-substituted phthalimide. These enhanced properties are attributed to a lower packing density. Consequently, the energy density of the proposed redox couple is greatly enhanced from butyl substitution. Furthermore, the results of the stack flow cell test with N,N,N',N'-tetramethyl-p-phenylenediamine positive redox couple show advantageous features of this non-aqueous flow battery system: a stable Coulombic efficiency and high working voltage.

A stereoselective, catalytic strategy for the in-flow synthesis of advanced precursors of rasagiline and tamsulosin.

PubMed

Brenna, Davide; Pirola, Margherita; Raimondi, Laura; Burke, Anthony J; Benaglia, Maurizio

2017-12-01

The diastereoselective, trichlorosilane-mediate reduction of imines, bearing different and removable chiral auxiliaries, in combination either with achiral bases or catalytic amounts of chiral Lewis bases, was investigated to afford immediate precursors of chiral APIs (Active Pharmaceutical Ingredients). The carbon-nitrogen double bond reduction was successfully performed in batch and in flow mode, in high yields and almost complete stereocontrol. By this metal-free approach, the formal synthesis of rasagiline and tamsulosin was successfully accomplished in micro(meso) flow reactors, under continuous flow conditions. The results of these explorative studies represent a new, important step towards the development of automated processes for the preparation of enantiopure biologically active compounds. Copyright © 2017 Elsevier Ltd. All rights reserved.

FastLane: Agile Drop Notification for Datacenter Networks

DTIC Science & Technology

2013-10-23

interactivity dead- lines mean that networks are increasingly evaluated on high percentile completion times of these short flows. Achieving consistent flow...triggering retransmissions based on out-of-order delivery. We evaluate FastLane in a number of scenarios, us- ing both testbed experiments and simulations...Results from our evaluation demonstrate that FastLane improves the 99.9th percentile completion time of short flows by up to 75% compared to TCP

An efficient multi-dimensional implementation of VSIAM3 and its applications to free surface flows

NASA Astrophysics Data System (ADS)

Yokoi, Kensuke; Furuichi, Mikito; Sakai, Mikio

2017-12-01

We propose an efficient multidimensional implementation of VSIAM3 (volume/surface integrated average-based multi-moment method). Although VSIAM3 is a highly capable fluid solver based on a multi-moment concept and has been used for a wide variety of fluid problems, VSIAM3 could not simulate some simple benchmark problems well (for instance, lid-driven cavity flows) due to relatively high numerical viscosity. In this paper, we resolve the issue by using the efficient multidimensional approach. The proposed VSIAM3 is shown to capture lid-driven cavity flows of the Reynolds number up to Re = 7500 with a Cartesian grid of 128 × 128, which was not capable for the original VSIAM3. We also tested the proposed framework in free surface flow problems (droplet collision and separation of We = 40 and droplet splashing on a superhydrophobic substrate). The numerical results by the proposed VSIAM3 showed reasonable agreements with these experiments. The proposed VSIAM3 could capture droplet collision and separation of We = 40 with a low numerical resolution (8 meshes for the initial diameter of droplets). We also simulated free surface flows including particles toward non-Newtonian flow applications. These numerical results have showed that the proposed VSIAM3 can robustly simulate interactions among air, particles (solid), and liquid.

Correlations of Surface Deformation and 3D Flow Field in a Compliant Wall Turbulent Channel Flow.

NASA Astrophysics Data System (ADS)

Wang, Jin; Zhang, Cao; Katz, Joseph

2015-11-01

This study focuses on the correlations between surface deformation and flow features, including velocity, vorticity and pressure, in a turbulent channel flow over a flat, compliant Polydimethylsiloxane (PDMS) wall. The channel centerline velocity is 2.5 m/s, and the friction Reynolds number is 2.3x103. Analysis is based on simultaneous measurements of the time resolved 3D velocity and surface deformation using tomographic PIV and Mach-Zehnder Interferometry. The volumetric pressure distribution is calculated plane by plane by spatially integrating the material acceleration using virtual boundary, omni-directional method. Conditional sampling based on local high/low pressure and deformation events reveals the primary flow structures causing the deformation. High pressure peaks appear at the interface between sweep and ejection, whereas the negative deformations peaks (dent) appear upstream, under the sweeps. The persistent phase lag between flow and deformations are presumably caused by internal damping within the PDMS. Some of the low pressure peaks and strong ejections are located under the head of hairpin vortices, and accordingly, are associated with positive deformation (bump). Others bumps and dents are correlated with some spanwise offset large inclined quasi-streamwise vortices that are not necessarily associated with hairpins. Sponsored by ONR.

A pilot study of change in cerebral activity during personality rating by questionnaire and personal computer.

PubMed

Sato, Emi; Matsuda, Kouhei

2018-06-11

The purpose of this study was to examine cerebral blood flow in the frontal cortex area during personality self-rating tasks. Our two hypotheses were (1) cerebral blood flow varies based on personality rating condition and (2) cerebral blood flow varies based on the personality traits. This experiment measured cerebral blood flow under 3 personal computer rating conditions and 2 questionnaire conditions. Comparing the rating conditions, the results of the t-test indicated that cerebral blood flow was higher in the questionnaire condition than it was in the personal computer condition. With respect to the Big Five, the result of the correlation coefficient, that is, cerebral blood flow during a personality rating task, changed according to the trait for agreeableness. The results of the analysis of the 5-cluster on individual differences indicated that certain personality traits were related to the factors that increased or decreased cerebral blood flow. An analysis of variance indicated that openness to experience and Behavioural Activation System-drive was significant given that participants with high intellectual curiosity were motivated in this experiment, thus, their cerebral blood flow may have increased. The significance of this experiment was that by employing certain performance measures we could examine differences in physical changes based on personality traits. © 2018 International Union of Psychological Science.

Nanostructured tracers for laser-based diagnostics in high-speed flows

NASA Astrophysics Data System (ADS)

Ghaemi, S.; Schmidt-Ott, A.; Scarano, F.

2010-10-01

The potential application of aggregates of nanoparticles for high-speed flow diagnostics is investigated. Aluminum nanoparticles around 10 nm in diameter are produced by spark discharge in argon gas. Through rapid coagulation and oxidation, aggregates of small effective density are formed. They are characterized by microscopy and their aerodynamics and optical properties are theoretically evaluated. The performance of the aggregates is experimentally investigated across an oblique shock wave in a supersonic wind tunnel of 3 × 3 cm2 cross-section at Mach 2. Particle image velocimetry is used to quantify the time response of the aggregates. The investigations are also carried out on compact titanium agglomerates to provide a base for comparison. The results yield a relaxation time of 0.27 µs for the nanostructured aluminum aggregates, which is an order of magnitude reduction with respect to the compact titanium nanoparticles. This work demonstrates the applicability of nanostructured aggregates for laser-based diagnostics in supersonic and hypersonic flows.

Numerical models of jet disruption in cluster cooling flows

NASA Technical Reports Server (NTRS)

Loken, Chris; Burns, Jack O.; Roettiger, Kurt; Norman, Mike

1993-01-01

We present a coherent picture for the formation of the observed diverse radio morphological structures in dominant cluster galaxies based on the jet Mach number. Realistic, supersonic, steady-state cooling flow atmospheres are evolved numerically and then used as the ambient medium through which jets of various properties are propagated. Low Mach number jets effectively stagnate due to the ram pressure of the cooling flow atmosphere while medium Mach number jets become unstable and disrupt in the cooling flow to form amorphous structures. High Mach number jets manage to avoid disruption and are able to propagate through the cooling flow.

Progress with multigrid schemes for hypersonic flow problems

NASA Technical Reports Server (NTRS)

Radespiel, R.; Swanson, R. C.

1991-01-01

Several multigrid schemes are considered for the numerical computation of viscous hypersonic flows. For each scheme, the basic solution algorithm uses upwind spatial discretization with explicit multistage time stepping. Two level versions of the various multigrid algorithms are applied to the two dimensional advection equation, and Fourier analysis is used to determine their damping properties. The capabilities of the multigrid methods are assessed by solving three different hypersonic flow problems. Some new multigrid schemes based on semicoarsening strategies are shown to be quite effective in relieving the stiffness caused by the high aspect ratio cells required to resolve high Reynolds number flows. These schemes exhibit good convergence rates for Reynolds numbers up to 200 x 10(exp 6) and Mach numbers up to 25.

A nano cold-wire for velocity measurements

NASA Astrophysics Data System (ADS)

Huang, Yi-Chun; Fu, Matthew; Fan, Yuyang; Byers, Clayton; Hultmark, Marcus

2016-11-01

We introduce a novel, strain-based sensor for both gaseous and liquid flows. The sensor consists of a free-standing, electrically conductive, nanoscale ribbon suspended between silicon supports. Due to its size, the nanoribbon deflects in flow under viscously dominated fluid forcing, which induces axial strain and a resistance change in the sensing element. The change in resistance can then be measured by a Wheatstone bridge, resulting in straightforward design and operation of the sensor. Since its operating principle is based on viscous fluid forcing, the sensor has high sensitivity especially in liquid or other highly viscous flows. A simple analytical model to understand the relation between forcing and strain is derived from the geometric and material constraints, and preliminary analysis using a low order model of the dynamic systems suggests that the sensor has a high frequency response. Lastly, a cylindrical structure to house the sensor with an axial and ventral channel to generate a pressure differential is being considered for typical velocimetry applications.

Brief Communication: A low-cost Arduino®-based wire extensometer for earth flow monitoring

NASA Astrophysics Data System (ADS)

Guerriero, Luigi; Guerriero, Giovanni; Grelle, Gerardo; Guadagno, Francesco M.; Revellino, Paola

2017-06-01

Continuous monitoring of earth flow displacement is essential for the understanding of the dynamic of the process, its ongoing evolution and designing mitigation measures. Despite its importance, it is not always applied due to its expense and the need for integration with additional sensors to monitor factors controlling movement. To overcome these problems, we developed and tested a low-cost Arduino-based wire-rail extensometer integrating a data logger, a power system and multiple digital and analog inputs. The system is equipped with a high-precision position transducer that in the test configuration offers a measuring range of 1023 mm and an associated accuracy of ±1 mm, and integrates an operating temperature sensor that should allow potential thermal drift that typically affects this kind of systems to be identified and corrected. A field test, conducted at the Pietrafitta earth flow where additional monitoring systems had been installed, indicates a high reliability of the measurement and a high monitoring stability without visible thermal drift.

Sheathless focusing and separation of microparticles using tilted angle travelling surface acoustic waves.

PubMed

Ahmed, Husnain; Destgeer, Ghulam; Park, Jinsoo; Afzal, Muhammad; Sung, Hyung Jin

2018-06-18

The sheathless focusing and separation of microparticles is an important pre-processing step in various biochemical assays in which enriched sample isolation is critical. Most previous microfluidic particle separation techniques have used a sheath flow to achieve efficient sample focusing. The sheath flow diluted the analyte, and required additional microchannels and accurate flow control. We demonstrated a tilted angle travelling surface acoustic wave (taTSAW)-based sheathless focusing and separation of particles in a continuous flow. The proposed device consisted of a piezoelectric substrate with a pair of interdigitated transducers (IDTs) deposited at two different angles relative to the flow direction. A Y-shaped polydimethylsiloxane (PDMS) microchannel having one inlet and two outlet ports was positioned on top of the IDTs such that the acoustic energy coupling into the fluid was maximized and wave attenuation by the PDMS walls was minimized. The two IDTs independently produced high-frequency taTSAWs, which propagated at ±30° with respect to the flow direction and imparted a direct acoustic radiation force onto the target particles. A sample mixture containing 4.8 and 3.2 µm particles was focused and then separated by the actuation of the IDTs at 194 and 136 MHz frequencies, respectively, without using an additional sheath flow. The proposed taTSAW-based particle separation device offered a high purity > 99% at the both outlets over a wide range of flow speeds (up to 83.3 mm/s).

Optimal design of high damping force engine mount featuring MR valve structure with both annular and radial flow paths

NASA Astrophysics Data System (ADS)

Nguyen, Q. H.; Choi, S. B.; Lee, Y. S.; Han, M. S.

2013-11-01

This paper focuses on the optimal design of a compact and high damping force engine mount featuring magnetorheological fluid (MRF). In the mount, a MR valve structure with both annular and radial flows is employed to generate a high damping force. First, the configuration and working principle of the proposed MR mount is introduced. The MRF flows in the mount are then analyzed and the governing equations of the MR mount are derived based on the Bingham plastic behavior of the MRF. An optimal design of the MR mount is then performed to find the optimal structure of the MR valve to generate a maximum damping force with certain design constraints. In addition, the gap size of MRF ducts is empirically chosen considering the ‘lockup’ problem of the mount at high frequency. Performance of the optimized MR mount is then evaluated based on finite element analysis and discussions on performance results of the optimized MR mount are given. The effectiveness of the proposed MR engine mount is demonstrated via computer simulation by presenting damping force and power consumption.

In situ IR and X-ray high spatial-resolution microspectroscopy measurements of multistep organic transformation in flow microreactor catalyzed by Au nanoclusters.

PubMed

Gross, Elad; Shu, Xing-Zhong; Alayoglu, Selim; Bechtel, Hans A; Martin, Michael C; Toste, F Dean; Somorjai, Gabor A

2014-03-05

Analysis of catalytic organic transformations in flow reactors and detection of short-lived intermediates are essential for optimization of these complex reactions. In this study, spectral mapping of a multistep catalytic reaction in a flow microreactor was performed with a spatial resolution of 15 μm, employing micrometer-sized synchrotron-based IR and X-ray beams. Two nanometer sized Au nanoclusters were supported on mesoporous SiO2, packed in a flow microreactor, and activated toward the cascade reaction of pyran formation. High catalytic conversion and tunable products selectivity were achieved under continuous flow conditions. In situ synchrotron-sourced IR microspectroscopy detected the evolution of the reactant, vinyl ether, into the primary product, allenic aldehyde, which then catalytically transformed into acetal, the secondary product. By tuning the residence time of the reactants in a flow microreactor a detailed analysis of the reaction kinetics was performed. An in situ micrometer X-ray absorption spectroscopy scan along the flow reactor correlated locally enhanced catalytic conversion, as detected by IR microspectroscopy, to areas with high concentration of Au(III), the catalytically active species. These results demonstrate the fundamental understanding of the mechanism of catalytic reactions which can be achieved by the detailed mapping of organic transformations in flow reactors.

An experimental investigation on fluid dynamics of an automotive torque converter

NASA Astrophysics Data System (ADS)

Dong, Yu

The objective of the automotive torque converter fluid dynamics experimental investigation is to understand the flow field inside the torque converter, improve the performance, and increase the fuel economy of vehicles. A high-frequency response five-hole probe was developed for the unsteady flow measurement. The dynamic performance of this probe was examined, and the corresponding data processing technique was also developed. The accuracy of this probe unsteady flow measurement was assessed using a hot-film sensor and a high-frequency response total pressure Pitot probe. The pump passage relative flow field was measured by a rotating five-hole probe system at three chord-wise locations. The rotating probe system is designed and developed for both pump and turbine flow measurement, and it was proved to be accurate and successful. A strong secondary flow is observed to dominate the flow structure at the pump mid-chord. At the pump 3/4 chord, the flow concentration on the pressure side is clearly observed. The secondary flow is found to change direction of rotation between the 3/4 chord and the 4/4 chord. High losses are found in the core-suction corner "wake" flow. The pump exit and turbine exit unsteady flow fields were measured by a high-frequency response five-hole probe in the stationary frame. At the pump exit, the flow is concentrated on the pressure side due to the strong secondary flow in the pump passage. A strong secondary flow is observed. At the turbine exit, a fully developed flow is found caused by the turbulent mixing. The stator exit steady flow was measured by a conventional five-hole probe. A strong secondary flow is found due to the inlet vorticity and axial velocity deficit near the core. The radially inward velocity and the secondary flow produce a large radial transport of mass flow in the stator passage. The stator passage flow is found to be turbulent at the normal operating condition by the measurement using the surface hot-film sensors mounted on the stator blade surface. Based on the experimental data and analysis, recommendations are proposed for the hydraulic design and the fluid dynamics research of the torque converter.

Relationship between salivary immunoglobulin a, lactoferrin and lysozyme flow rates and lifestyle factors in Japanese children: a cross-sectional study.

PubMed

Ide, Momo; Saruta, Juri; To, Masahiro; Yamamoto, Yuko; Sugimoto, Masahiro; Fuchida, Shinya; Yokoyama, Mina; Kimoto, Shigenari; Tsukinoki, Keiichi

2016-10-01

The antimicrobial substances in saliva contribute to the maintenance of both oral health and overall health of the body. Therefore, the associations among immunoglobulin A (IgA), lactoferrin and lysozyme flow rates in the saliva of children, and their relationships with the physical attributes and lifestyle factors of children, were examined. Saliva was collected from 90 children who visited the Kanagawa Dental University Hospital Pediatric Dentistry, and questionnaires were completed by guardians. IgA, lactoferrin and lysozyme concentrations were measured in the saliva samples using enzyme-linked immunosorbent assays (ELISAs). The IgA flow rate in saliva increased as age, height and weight increased. A correlation was found between lactoferrin and lysozyme flow rates. When the antimicrobial substance flow rates in the saliva were divided into two groups of 22 children each based on the highest and lowest quartiles, children with either a low or high IgA flow rate also had a high or low lactoferrin flow rate, respectively. The same pattern was observed for lactoferrin and lysozyme flow rates. There is a high probability that the IgA flow rate in the saliva of children reflects and corresponds to the developmental status of immune function as the child ages and increases in height and weight. The flow rates of lactoferrin and lysozyme were correlated in children. In addition, regarding lifestyle factors, the duration of sleep and lactoferrin flow rate were also related.

Natural history of definitive diverticular hemorrhage based upon stigmata of recent hemorrhage and colonoscopic Doppler blood flow monitoring for risk stratification and definitive hemostasis

PubMed Central

Jensen, Dennis M.; Ohning, Gordon V.; Kovacs, Thomas O.G.; Jutabha, Rome; Ghassemi, Kevin; Dulai, Gareth S.; Machicado, Gustavo A.

2015-01-01

BACKGROUND AND AIMS Few prospective reports describe the short term natural history of colon diverticular hemorrhage based upon stigmata of recent hemorrhage and none include blood flow detection for risk stratification or as a guide to definitive hemostasis. Our purposes are to report the 30 day natural history of definitive diverticular hemorrhage based upon stigmata and to describe Doppler probe blood flow detection and as a guide to definitive hemostasis. METHODS Different cohorts of patients with severe diverticular bleeding and stigmata on urgent colonoscopy are reported. For 30 day natural history, patients were treated medically. If severe rebleeding occurred, they had surgical or angiographic treatment. Natural history with major stigmata (active bleeding, visible vessel, or adherent clot) and no stigmata or flat spots after washing away clots are reported. Doppler probe detection of arterial blood flow underneath stigmata before and after hemostasis is also reported in a recent cohort. RESULTS For natural history patients with major stigmata treated medically had 65.8% (25/38) rebleeding rates and 44.7% (17/38) had intervention for hemostasis. Patients with spots or clean bases had no rebleeding. Doppler probe detected arterial blood flow in 92% of major stigmata, none after hemostasis and no one rebled. CONCLUSIONS 1. Patients with major stigmata treated medically had high rates of rebleeding and intervention for hemostasis. 2. Patients with clean diverticula or only flat spots had no rebleeding. 3. High rates of arterial blood flow were detected under major stigmata with Doppler probe but with obliteration by hemostasis no rebleeding occurred. PMID:26227931

Effect of inlet modelling on surface drainage in coupled urban flood simulation

NASA Astrophysics Data System (ADS)

Jang, Jiun-Huei; Chang, Tien-Hao; Chen, Wei-Bo

2018-07-01

For a highly developed urban area with complete drainage systems, flood simulation is necessary for describing the flow dynamics from rainfall, to surface runoff, and to sewer flow. In this study, a coupled flood model based on diffusion wave equations was proposed to simulate one-dimensional sewer flow and two-dimensional overland flow simultaneously. The overland flow model provides details on the rainfall-runoff process to estimate the excess runoff that enters the sewer system through street inlets for sewer flow routing. Three types of inlet modelling are considered in this study, including the manhole-based approach that ignores the street inlets by draining surface water directly into manholes, the inlet-manhole approach that drains surface water into manholes that are each connected to multiple inlets, and the inlet-node approach that drains surface water into sewer nodes that are connected to individual inlets. The simulation results were compared with a high-intensity rainstorm event that occurred in 2015 in Taipei City. In the verification of the maximum flood extent, the two approaches that considered street inlets performed considerably better than that without street inlets. When considering the aforementioned models in terms of temporal flood variation, using manholes as receivers leads to an overall inefficient draining of the surface water either by the manhole-based approach or by the inlet-manhole approach. Using the inlet-node approach is more reasonable than using the inlet-manhole approach because the inlet-node approach greatly reduces the fluctuation of the sewer water level. The inlet-node approach is more efficient in draining surface water by reducing flood volume by 13% compared with the inlet-manhole approach and by 41% compared with the manhole-based approach. The results show that inlet modeling has a strong influence on drainage efficiency in coupled flood simulation.

Computational modeling of magnetic particle margination within blood flow through LAMMPS

NASA Astrophysics Data System (ADS)

Ye, Huilin; Shen, Zhiqiang; Li, Ying

2017-11-01

We develop a multiscale and multiphysics computational method to investigate the transport of magnetic particles as drug carriers in blood flow under influence of hydrodynamic interaction and external magnetic field. A hybrid coupling method is proposed to handle red blood cell (RBC)-fluid interface (CFI) and magnetic particle-fluid interface (PFI), respectively. Immersed boundary method (IBM)-based velocity coupling is used to account for CFI, which is validated by tank-treading and tumbling behaviors of a single RBC in simple shear flow. While PFI is captured by IBM-based force coupling, which is verified through movement of a single magnetic particle under non-uniform external magnetic field and breakup of a magnetic chain in rotating magnetic field. These two components are seamlessly integrated within the LAMMPS framework, which is a highly parallelized molecular dynamics solver. In addition, we also implement a parallelized lattice Boltzmann simulator within LAMMPS to handle the fluid flow simulation. Based on the proposed method, we explore the margination behaviors of magnetic particles and magnetic chains within blood flow. We find that the external magnetic field can be used to guide the motion of these magnetic materials and promote their margination to the vascular wall region. Moreover, the scaling performance and speedup test further confirm the high efficiency and robustness of proposed computational method. Therefore, it provides an efficient way to simulate the transport of nanoparticle-based drug carriers within blood flow in a large scale. The simulation results can be applied in the design of efficient drug delivery vehicles that optimally accumulate within diseased tissue, thus providing better imaging sensitivity, therapeutic efficacy and lower toxicity.

Note: Ultrasonic gas flowmeter based on optimized time-of-flight algorithms

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, X. F.; Tang, Z. A.

2011-04-15

A new digital signal processor based single path ultrasonic gas flowmeter is designed, constructed, and experimentally tested. To achieve high accuracy measurements, an optimized ultrasound driven method of incorporation of the amplitude modulation and the phase modulation of the transmit-receive technique is used to stimulate the transmitter. Based on the regularities among the received envelope zero-crossings, different received signal's signal-to-noise ratio situations are discriminated and optional time-of-flight algorithms are applied to take flow rate calculations. Experimental results from the dry calibration indicate that the designed flowmeter prototype can meet the zero-flow verification test requirements of the American Gas Association Reportmore » No. 9. Furthermore, the results derived from the flow calibration prove that the proposed flowmeter prototype can measure flow rate accurately in the practical experiments, and the nominal accuracies after FWME adjustment are lower than 0.8% throughout the calibration range.« less

Renewable Wood Pulp Paper Reactor with Hierarchical Micro/Nanopores for Continuous-Flow Nanocatalysis.

PubMed

Koga, Hirotaka; Namba, Naoko; Takahashi, Tsukasa; Nogi, Masaya; Nishina, Yuta

2017-06-22

Continuous-flow nanocatalysis based on metal nanoparticle catalyst-anchored flow reactors has recently provided an excellent platform for effective chemical manufacturing. However, there has been limited progress in porous structure design and recycling systems for metal nanoparticle-anchored flow reactors to create more efficient and sustainable catalytic processes. In this study, traditional paper is used for a highly efficient, recyclable, and even renewable flow reactor by tailoring the ultrastructures of wood pulp. The "paper reactor" offers hierarchically interconnected micro- and nanoscale pores, which can act as convective-flow and rapid-diffusion channels, respectively, for efficient access of reactants to metal nanoparticle catalysts. In continuous-flow, aqueous, room-temperature catalytic reduction of 4-nitrophenol to 4-aminophenol, a gold nanoparticle (AuNP)-anchored paper reactor with hierarchical micro/nanopores provided higher reaction efficiency than state-of-the-art AuNP-anchored flow reactors. Inspired by traditional paper materials, successful recycling and renewal of AuNP-anchored paper reactors were also demonstrated while high reaction efficiency was maintained. © 2017 The Authors. Published by Wiley-VCH Verlag GmbH & Co. KGaA.

Renewable Wood Pulp Paper Reactor with Hierarchical Micro/Nanopores for Continuous‐Flow Nanocatalysis

PubMed Central

Namba, Naoko; Takahashi, Tsukasa; Nogi, Masaya; Nishina, Yuta

2017-01-01

Abstract Continuous‐flow nanocatalysis based on metal nanoparticle catalyst‐anchored flow reactors has recently provided an excellent platform for effective chemical manufacturing. However, there has been limited progress in porous structure design and recycling systems for metal nanoparticle‐anchored flow reactors to create more efficient and sustainable catalytic processes. In this study, traditional paper is used for a highly efficient, recyclable, and even renewable flow reactor by tailoring the ultrastructures of wood pulp. The “paper reactor” offers hierarchically interconnected micro‐ and nanoscale pores, which can act as convective‐flow and rapid‐diffusion channels, respectively, for efficient access of reactants to metal nanoparticle catalysts. In continuous‐flow, aqueous, room‐temperature catalytic reduction of 4‐nitrophenol to 4‐aminophenol, a gold nanoparticle (AuNP)‐anchored paper reactor with hierarchical micro/nanopores provided higher reaction efficiency than state‐of‐the‐art AuNP‐anchored flow reactors. Inspired by traditional paper materials, successful recycling and renewal of AuNP‐anchored paper reactors were also demonstrated while high reaction efficiency was maintained. PMID:28394501

Evidence for the Activation of Shallow Preferential Flow Paths in a Tropical Panama Watershed Using Germanium and Silicon

NASA Astrophysics Data System (ADS)

Gardner, Christopher B.; Litt, Guy F.; Lyons, W. Berry; Ogden, Fred L.

2017-10-01

In humid tropical watersheds, the hydrologic flow paths taken by rain event waters and how they interact with groundwater and soil matrix water to form streamflow are poorly understood. Preferential flow paths (PFPs) confound storm infiltration processes, especially in the humid tropics where PFPs are common. This work applies germanium (Ge) and silicon (Si) as natural flow path tracers in conjunction with water stable isotopes and electrical conductivity to examine the rapid delivery of shallow soil water, the activation of PFPs, and event water partitioning in an experimental catchment in central Panama. We employed a three-component mixing model for hydrograph separation using the following end-member waters: (i) base flow (high [Si], low [Ge], and low Ge/Si ratio), (ii) dilute canopy throughfall (low [Si] and low [Ge]), and (iii) shallow (<15 cm) soil matrix water (low [Si], high [Ge], and high Ge/Si ratio). These three end-members bounded all observed Ge/Si streamflow ratios. During small rain events (<˜24 mm), base flow and dilute canopy throughfall components dominated stormflow. During larger precipitation events (>˜35 mm), we detected the third shallow soil water component with an elevated [Ge] and Ge/Si ratio. This component reached its maximum during the hydrograph's receding limb coincident with the maximum event fraction, and increased proportionally to the total storm rainfall exceeding ˜35 mm. Only shallow (<15 cm) soil matrix water exhibited elevated Ge concentrations and high Ge/Si ratios. This third component represents rapidly delivered soil matrix water combined with shallow lateral PFP activation through which event waters interact with soil minerals.

Label-free cell-cycle analysis by high-throughput quantitative phase time-stretch imaging flow cytometry

NASA Astrophysics Data System (ADS)

Mok, Aaron T. Y.; Lee, Kelvin C. M.; Wong, Kenneth K. Y.; Tsia, Kevin K.

2018-02-01

Biophysical properties of cells could complement and correlate biochemical markers to characterize a multitude of cellular states. Changes in cell size, dry mass and subcellular morphology, for instance, are relevant to cell-cycle progression which is prevalently evaluated by DNA-targeted fluorescence measurements. Quantitative-phase microscopy (QPM) is among the effective biophysical phenotyping tools that can quantify cell sizes and sub-cellular dry mass density distribution of single cells at high spatial resolution. However, limited camera frame rate and thus imaging throughput makes QPM incompatible with high-throughput flow cytometry - a gold standard in multiparametric cell-based assay. Here we present a high-throughput approach for label-free analysis of cell cycle based on quantitative-phase time-stretch imaging flow cytometry at a throughput of > 10,000 cells/s. Our time-stretch QPM system enables sub-cellular resolution even at high speed, allowing us to extract a multitude (at least 24) of single-cell biophysical phenotypes (from both amplitude and phase images). Those phenotypes can be combined to track cell-cycle progression based on a t-distributed stochastic neighbor embedding (t-SNE) algorithm. Using multivariate analysis of variance (MANOVA) discriminant analysis, cell-cycle phases can also be predicted label-free with high accuracy at >90% in G1 and G2 phase, and >80% in S phase. We anticipate that high throughput label-free cell cycle characterization could open new approaches for large-scale single-cell analysis, bringing new mechanistic insights into complex biological processes including diseases pathogenesis.

Ultrafast Ultrasound Imaging of Ocular Anatomy and Blood Flow

PubMed Central

Urs, Raksha; Ketterling, Jeffrey A.; Silverman, Ronald H.

2016-01-01

Purpose Ophthalmic ultrasound imaging is currently performed with mechanically scanned single-element probes. These probes have limited capabilities overall and lack the ability to image blood flow. Linear-array systems are able to detect blood flow, but these systems exceed ophthalmic acoustic intensity safety guidelines. Our aim was to implement and evaluate a new linear-array–based technology, compound coherent plane-wave ultrasound, which offers ultrafast imaging and depiction of blood flow at safe acoustic intensity levels. Methods We compared acoustic intensity generated by a 128-element, 18-MHz linear array operated in conventionally focused and plane-wave modes and characterized signal-to-noise ratio (SNR) and lateral resolution. We developed plane-wave B-mode, real-time color-flow, and high-resolution depiction of slow flow in postprocessed data collected continuously at a rate of 20,000 frames/s. We acquired in vivo images of the posterior pole of the eye by compounding plane-wave images acquired over ±10° and produced images depicting orbital and choroidal blood flow. Results With the array operated conventionally, Doppler modes exceeded Food and Drug Administration safety guidelines, but plane-wave modalities were well within guidelines. Plane-wave data allowed generation of high-quality compound B-mode images, with SNR increasing with the number of compounded frames. Real-time color-flow Doppler readily visualized orbital blood flow. Postprocessing of continuously acquired data blocks of 1.6-second duration allowed high-resolution depiction of orbital and choroidal flow over the cardiac cycle. Conclusions Newly developed high-frequency linear arrays in combination with plane-wave techniques present opportunities for the evaluation of ocular anatomy and blood flow, as well as visualization and analysis of other transient phenomena such as vessel wall motion over the cardiac cycle and saccade-induced vitreous motion. PMID:27428169

High-resolution submillimeter-wave radiometry of supersonic flow

NASA Technical Reports Server (NTRS)

Dionne, G. F.; Weiss, J. A.; Fitzgerald, J. F.; Fetterman, H. R.; Litvak, M. M.

1983-01-01

The recent development of a high-resolution submillimeter-wave heterodyne radiometer has made possible the first measurements of H2O molecule rotational line excitation temperatures and detailed profiles in supersonic flow. Absorption signals were measured across the flow for the 2/11/ from 2//02/ (752 GHz) para-H2O rotational transition against a hot background. These signals decrease downstream owing to the volume expansion of the gas away from the sonic nozle exit in the high-vacuum chamber. Radiative transfer calculations based on the large-velocity-gradient approximation and multilevel statistical equilibrium agree with these results and with the measured spectral line shapes. The data reveal nearly isentropic gas expansion and cooling. These studies have shown that submillimeter-wave heterodyne radiometry can be useful for remote sensing of supersonic flow with low mass flux, provided the signal transmission is through a dry or thin atmosphere.

Automated Low-Cost Smartphone-Based Lateral Flow Saliva Test Reader for Drugs-of-Abuse Detection.

PubMed

Carrio, Adrian; Sampedro, Carlos; Sanchez-Lopez, Jose Luis; Pimienta, Miguel; Campoy, Pascual

2015-11-24

Lateral flow assay tests are nowadays becoming powerful, low-cost diagnostic tools. Obtaining a result is usually subject to visual interpretation of colored areas on the test by a human operator, introducing subjectivity and the possibility of errors in the extraction of the results. While automated test readers providing a result-consistent solution are widely available, they usually lack portability. In this paper, we present a smartphone-based automated reader for drug-of-abuse lateral flow assay tests, consisting of an inexpensive light box and a smartphone device. Test images captured with the smartphone camera are processed in the device using computer vision and machine learning techniques to perform automatic extraction of the results. A deep validation of the system has been carried out showing the high accuracy of the system. The proposed approach, applicable to any line-based or color-based lateral flow test in the market, effectively reduces the manufacturing costs of the reader and makes it portable and massively available while providing accurate, reliable results.

Uncertainty in simulated groundwater-quality trends in transient flow

USGS Publications Warehouse

Starn, J. Jeffrey; Bagtzoglou, Amvrossios; Robbins, Gary A.

2013-01-01

In numerical modeling of groundwater flow, the result of a given solution method is affected by the way in which transient flow conditions and geologic heterogeneity are simulated. An algorithm is demonstrated that simulates breakthrough curves at a pumping well by convolution-based particle tracking in a transient flow field for several synthetic basin-scale aquifers. In comparison to grid-based (Eulerian) methods, the particle (Lagrangian) method is better able to capture multimodal breakthrough caused by changes in pumping at the well, although the particle method may be apparently nonlinear because of the discrete nature of particle arrival times. Trial-and-error choice of number of particles and release times can perhaps overcome the apparent nonlinearity. Heterogeneous aquifer properties tend to smooth the effects of transient pumping, making it difficult to separate their effects in parameter estimation. Porosity, a new parameter added for advective transport, can be accurately estimated using both grid-based and particle-based methods, but predictions can be highly uncertain, even in the simple, nonreactive case.

Vortex Imprints at the Wall, But Not in the Bulk, Distinguish Ruptured from Unruptured Intracranial Aneurysms

NASA Astrophysics Data System (ADS)

Varble, Nicole; Meng, Hui

2015-11-01

Intracranial aneurysms affect 3% of the population. Risk stratification of aneurysms is important, as rupture often leads to death or permanent disability. Image-based CFD analyses of patient-specific aneurysms have identified low and oscillatory wall shear stress to predict rupture. These stresses are sensed biologically at the luminal wall, but the flow dynamics related to aneurysm rupture requires further understanding. We have conducted two studies: one examines vortex dynamics, and the other, high frequency flow fluctuations in patient-specific aneurysms. In the first study, based on Q-criterion vortex identification, we developed two measures to quantify regions within the aneurysm where rotational flow is dominate: the ratio of volume or surface area where Q >0 vs. the total aneurysmal volume or surface area, respectively termed volume vortex fraction (VVF) and surface vortex fraction (SVF). Statistical analysis of 204 aneurysms shows that SVF, but not VVF, distinguishes ruptured from unruptured aneurysms, suggesting that once again, the local flow patterns on the wall is directly relevant to rupture. In the second study, high-resolution CFD (high spatial and temporal resolutions and second-order discretization schemes) on 56 middle cerebral artery aneurysms shows the presence of temporal fluctuations in 8 aneurysms, but such flow instability bears no correlation with rupture. Support for this work was partially provided by NIH grant (R01 NS091075-01) and a grant from Toshiba Medical Systems Corp.

Squirt flow due to interfacial water films in hydrate bearing sediments

NASA Astrophysics Data System (ADS)

Sell, Kathleen; Quintal, Beatriz; Kersten, Michael; Saenger, Erik H.

2018-05-01

Sediments containing gas hydrate dispersed in the pore space are known to show a characteristic seismic anomaly which is a high attenuation along with increasing seismic velocities. Currently, this observation cannot be fully explained albeit squirt-flow type mechanisms on the microscale have been speculated to be the cause. Recent major findings from in situ experiments, using the gas in excess and water in excess formation method, and coupled with high-resolution synchrotron-based X-ray micro-tomography, have revealed the systematic presence of thin water films between the quartz grains and the encrusting hydrate. The data obtained from these experiments underwent an image processing procedure to quantify the thicknesses and geometries of the aforementioned interfacial water films. Overall, the water films vary from sub-micrometer to a few micrometers in thickness. In addition, some of the water films interconnect through water bridges. This geometrical analysis is used to propose a new conceptual squirt flow model for hydrate bearing sediments. A series of numerical simulations is performed considering variations of the proposed model to study seismic attenuation caused by such thin water films. Our results support previous speculation that squirt flow can explain high attenuation at seismic frequencies in hydrate bearing sediments, but based on a conceptual squirt flow model which is geometrically different than those previously considered.

Optimization of an electrokinetic mixer for microfluidic applications.

PubMed

Bockelmann, Hendryk; Heuveline, Vincent; Barz, Dominik P J

2012-06-01

This work is concerned with the investigation of the concentration fields in an electrokinetic micromixer and its optimization in order to achieve high mixing rates. The mixing concept is based on the combination of an alternating electrical excitation applied to a pressure-driven base flow in a meandering microchannel geometry. The electrical excitation induces a secondary electrokinetic velocity component, which results in a complex flow field within the meander bends. A mathematical model describing the physicochemical phenomena present within the micromixer is implemented in an in-house finite-element-method code. We first perform simulations comparable to experiments concerned with the investigation of the flow field in the bends. The comparison of the complex flow topology found in simulation and experiment reveals excellent agreement. Hence, the validated model and numerical schemes are employed for a numerical optimization of the micromixer performance. In detail, we optimize the secondary electrokinetic flow by finding the best electrical excitation parameters, i.e., frequency and amplitude, for a given waveform. Two optimized electrical excitations featuring a discrete and a continuous waveform are discussed with respect to characteristic time scales of our mixing problem. The results demonstrate that the micromixer is able to achieve high mixing degrees very rapidly.

Optimization of an electrokinetic mixer for microfluidic applications

PubMed Central

Bockelmann, Hendryk; Heuveline, Vincent; Barz, Dominik P. J.

2012-01-01

This work is concerned with the investigation of the concentration fields in an electrokinetic micromixer and its optimization in order to achieve high mixing rates. The mixing concept is based on the combination of an alternating electrical excitation applied to a pressure-driven base flow in a meandering microchannel geometry. The electrical excitation induces a secondary electrokinetic velocity component, which results in a complex flow field within the meander bends. A mathematical model describing the physicochemical phenomena present within the micromixer is implemented in an in-house finite-element-method code. We first perform simulations comparable to experiments concerned with the investigation of the flow field in the bends. The comparison of the complex flow topology found in simulation and experiment reveals excellent agreement. Hence, the validated model and numerical schemes are employed for a numerical optimization of the micromixer performance. In detail, we optimize the secondary electrokinetic flow by finding the best electrical excitation parameters, i.e., frequency and amplitude, for a given waveform. Two optimized electrical excitations featuring a discrete and a continuous waveform are discussed with respect to characteristic time scales of our mixing problem. The results demonstrate that the micromixer is able to achieve high mixing degrees very rapidly. PMID:22712034

Real-time monitoring of capacity loss for vanadium redox flow battery

NASA Astrophysics Data System (ADS)

Wei, Zhongbao; Bhattarai, Arjun; Zou, Changfu; Meng, Shujuan; Lim, Tuti Mariana; Skyllas-Kazacos, Maria

2018-06-01

The long-term operation of the vanadium redox flow battery is accompanied by ion diffusion across the separator and side reactions, which can lead to electrolyte imbalance and capacity loss. The accurate online monitoring of capacity loss is therefore valuable for the reliable and efficient operation of vanadium redox flow battery system. In this paper, a model-based online monitoring method is proposed to detect capacity loss in the vanadium redox flow battery in real time. A first-order equivalent circuit model is built to capture the dynamics of the vanadium redox flow battery. The model parameters are online identified from the onboard measureable signals with the recursive least squares, in seeking to keep a high modeling accuracy and robustness under a wide range of working scenarios. Based on the online adapted model, an observer is designed with the extended Kalman Filter to keep tracking both the capacity and state of charge of the battery in real time. Experiments are conducted on a lab-scale battery system. Results suggest that the online adapted model is able to simulate the battery behavior with high accuracy. The capacity loss as well as the state of charge can be estimated accurately in a real-time manner.

Use of thermoacoustic excitation for control of turbulent flow over a wall-mounted hump

NASA Astrophysics Data System (ADS)

Yeh, Chi-An; Munday, Phillip; Taira, Kunihiko

2014-11-01

We numerically examine the effectiveness of high-frequency acoustic excitation for drag reduction control of turbulent flow over a wall-mounted hump at a free stream Reynolds number of 500,000 and Mach number of 0.25. Actuation frequencies around Helmholtz number of 3 are considered based on the characteristics of recently developed graphene/carbon nanotube-based surface compliant loud speakers. The present study utilizes LES (CharLES) with an oscillatory heat flux boundary condition to produce high-intensity acoustic waves, which interact with the turbulent flow structures by introducing small-scale perturbations to the shear layer in the wake of the hump. With thermoacoustic control, the recirculation zone downstream of the hump becomes elongated with thinner shear layer profile compared to the uncontrolled case. This change in the flow shifts the low-pressure region of the wake further downstream and results in reduction in drag by 10% for two-dimensional and 15% for three-dimensional flows. The influence of actuation frequency and amplitude is also examined. This work is supported by the US Army Research Office (W911NF-13-1-0062, W911NF-14-1-0224).

10 CFR 430.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... identical water-passage design features that use the same path of water in the highest flow mode. Batch... as 8-foot high output lamps) with recessed double contact bases of nominal overall length of 96... (commonly referred to 4-foot miniature bipin high output lamps) with miniature bipin bases of nominal...

Perspectives in flow-based microfluidic gradient generators for characterizing bacterial chemotaxis

PubMed Central

Wolfram, Christopher J.; Rubloff, Gary W.; Luo, Xiaolong

2016-01-01

Chemotaxis is a phenomenon which enables cells to sense concentrations of certain chemical species in their microenvironment and move towards chemically favorable regions. Recent advances in microbiology have engineered the chemotactic properties of bacteria to perform novel functions, but traditional methods of characterizing chemotaxis do not fully capture the associated cell motion, making it difficult to infer mechanisms that link the motion to the microbiology which induces it. Microfluidics offers a potential solution in the form of gradient generators. Many of the gradient generators studied to date for this application are flow-based, where a chemical species diffuses across the laminar flow interface between two solutions moving through a microchannel. Despite significant research efforts, flow-based gradient generators have achieved mixed success at accurately capturing the highly subtle chemotactic responses exhibited by bacteria. Here we present an analysis encompassing previously published versions of flow-based gradient generators, the theories that govern their gradient-generating properties, and new, more practical considerations that result from experimental factors. We conclude that flow-based gradient generators present a challenge inherent to their design in that the residence time and gradient decay must be finely balanced, and that this significantly narrows the window for reliable observation and quantification of chemotactic motion. This challenge is compounded by the effects of shear on an ellipsoidal bacterium that causes it to preferentially align with the direction of flow and subsequently suppresses the cross-flow chemotactic response. These problems suggest that a static, non-flowing gradient generator may be a more suitable platform for chemotaxis studies in the long run, despite posing greater difficulties in design and fabrication. PMID:27917249

Perspectives in flow-based microfluidic gradient generators for characterizing bacterial chemotaxis.

PubMed

Wolfram, Christopher J; Rubloff, Gary W; Luo, Xiaolong

2016-11-01

Chemotaxis is a phenomenon which enables cells to sense concentrations of certain chemical species in their microenvironment and move towards chemically favorable regions. Recent advances in microbiology have engineered the chemotactic properties of bacteria to perform novel functions, but traditional methods of characterizing chemotaxis do not fully capture the associated cell motion, making it difficult to infer mechanisms that link the motion to the microbiology which induces it. Microfluidics offers a potential solution in the form of gradient generators. Many of the gradient generators studied to date for this application are flow-based, where a chemical species diffuses across the laminar flow interface between two solutions moving through a microchannel. Despite significant research efforts, flow-based gradient generators have achieved mixed success at accurately capturing the highly subtle chemotactic responses exhibited by bacteria. Here we present an analysis encompassing previously published versions of flow-based gradient generators, the theories that govern their gradient-generating properties, and new, more practical considerations that result from experimental factors. We conclude that flow-based gradient generators present a challenge inherent to their design in that the residence time and gradient decay must be finely balanced, and that this significantly narrows the window for reliable observation and quantification of chemotactic motion. This challenge is compounded by the effects of shear on an ellipsoidal bacterium that causes it to preferentially align with the direction of flow and subsequently suppresses the cross-flow chemotactic response. These problems suggest that a static, non-flowing gradient generator may be a more suitable platform for chemotaxis studies in the long run, despite posing greater difficulties in design and fabrication.

Tidal current energy potential of Nalón river estuary assessment using a high precision flow model

NASA Astrophysics Data System (ADS)

Badano, Nicolás; Valdés, Rodolfo Espina; Álvarez, Eduardo Álvarez

2018-05-01

Obtaining energy from tide currents in onshore locations is of great interest due to the proximity to the points of consumption. This opens the door to the feasibility of new installations based on hydrokinetic microturbines even in zones of moderate speed. In this context, the accuracy of energy predictions based on hydrodynamic models is of paramount importance. This research presents a high precision methodology based on a multidimensional hydrodynamic model that is used to study the energetic potential in estuaries. Moreover, it is able to estimate the flow variations caused by microturbine installations. The paper also shows the results obtained from the application of the methodology in a study of the Nalón river mouth (Asturias, Spain).

Superfluid high REynolds von Kármán experiment.

PubMed

Rousset, B; Bonnay, P; Diribarne, P; Girard, A; Poncet, J M; Herbert, E; Salort, J; Baudet, C; Castaing, B; Chevillard, L; Daviaud, F; Dubrulle, B; Gagne, Y; Gibert, M; Hébral, B; Lehner, Th; Roche, P-E; Saint-Michel, B; Bon Mardion, M

2014-10-01

The Superfluid High REynolds von Kármán experiment facility exploits the capacities of a high cooling power refrigerator (400 W at 1.8 K) for a large dimension von Kármán flow (inner diameter 0.78 m), which can work with gaseous or subcooled liquid (He-I or He-II) from room temperature down to 1.6 K. The flow is produced between two counter-rotating or co-rotating disks. The large size of the experiment allows exploration of ultra high Reynolds numbers based on Taylor microscale and rms velocity [S. B. Pope, Turbulent Flows (Cambridge University Press, 2000)] (Rλ > 10000) or resolution of the dissipative scale for lower Re. This article presents the design and first performance of this apparatus. Measurements carried out in the first runs of the facility address the global flow behavior: calorimetric measurement of the dissipation, torque and velocity measurements on the two turbines. Moreover first local measurements (micro-Pitot, hot wire,…) have been installed and are presented.

Superfluid high REynolds von Kármán experiment

NASA Astrophysics Data System (ADS)

Rousset, B.; Bonnay, P.; Diribarne, P.; Girard, A.; Poncet, J. M.; Herbert, E.; Salort, J.; Baudet, C.; Castaing, B.; Chevillard, L.; Daviaud, F.; Dubrulle, B.; Gagne, Y.; Gibert, M.; Hébral, B.; Lehner, Th.; Roche, P.-E.; Saint-Michel, B.; Bon Mardion, M.

2014-10-01

The Superfluid High REynolds von Kármán experiment facility exploits the capacities of a high cooling power refrigerator (400 W at 1.8 K) for a large dimension von Kármán flow (inner diameter 0.78 m), which can work with gaseous or subcooled liquid (He-I or He-II) from room temperature down to 1.6 K. The flow is produced between two counter-rotating or co-rotating disks. The large size of the experiment allows exploration of ultra high Reynolds numbers based on Taylor microscale and rms velocity [S. B. Pope, Turbulent Flows (Cambridge University Press, 2000)] (Rλ > 10000) or resolution of the dissipative scale for lower Re. This article presents the design and first performance of this apparatus. Measurements carried out in the first runs of the facility address the global flow behavior: calorimetric measurement of the dissipation, torque and velocity measurements on the two turbines. Moreover first local measurements (micro-Pitot, hot wire,…) have been installed and are presented.

Blurring the boundary between rapid granular flow and dense granular flow regimes: Evidence from DEM simulations

NASA Astrophysics Data System (ADS)

Tripathi, Anurag; Prasad, Mahesh; Kumar, Puneet

2017-11-01

The saturation of the effective friction coefficient for granular flows at high inertial numbers has been assumed widely by researchers, despite little simulation/experimental evidence. In contrast, a recent simulation study of plane shear flows by Mandal and Khakhar, suggests that the effective friction coefficient becomes maximum and then starts to decrease with increase in the inertial number for I > 0.5 . In order to investigate whether such a dip at higher inertial numbers is indeed a feature of granular rheology, we perform DEM simulations of chute flow of highly inelastic disks. We show that steady, fully developed flows are possible at inclinations much higher than those normally reported in literature. At such high inclinations, the flow is characterised by a significant slip at the base; the height of the layer increases by more than 300 % and kinetic energy of the layer increases by nearly 5 orders of magnitude. We observe, for the first time, steady chute flows at inertial number I 2 and show that the dip at higher inertial numbers can be observed in case of chute flow as well. The predictions of modified μ - I rheology, however, seem to remain valid in the bulk of the layer for packing fractions as low as 0.2. AT acknowledges the funding obtained from IIT Kanpur through the initiation Grant for this study.

Relations of Water Quality to Streamflow, Season, and Land Use for Four Tributaries to the Toms River, Ocean County, New Jersey, 1994-99

USGS Publications Warehouse

Baker, Ronald J.; Hunchak-Kariouk, Kathryn

2006-01-01

The effects of nonpoint-source contamination on the water quality of four tributaries to the Toms River in Ocean County, New Jersey, have been investigated in a 5-year study by the U.S. Geological Survey (USGS), in cooperation with the New Jersey Department of Environmental Protection (NJDEP). The purpose of the study was to relate the extent of land development to loads of nutrients and other contaminants to these streams, and ultimately to Barnegat Bay. Volumetric streamflow (discharge) was measured at 6 monitoring sites during 37 stormflow and base-flow sampling events over a 5-year period (May 1994-September 1999). Concentrations and yields (area-normalized instantaneous load values) of nitrogen and phosphorus species, total suspended solids, and fecal coliform bacteria were quantified, and pH, dissolved oxygen, and stream stage were monitored during base-flow conditions and storms. Sufficient data were collected to allow for a statistical evaluation of differences in water quality among streams in subbasins with high, medium, and low levels of land development. Long Swamp Creek, in a highly developed subbasin (64.2 percent developed); Wrangle Brook, in a moderately developed subbasin (34.5 percent); Davenport Branch, in a slightly developed subbasin (22.8 percent); and Jakes Branch, in an undeveloped subbasin (0 percent) are the subbasins selected for this study. No point-source discharges are known to be present on these streams. Water samples were collected and analyzed by the NJDEP, and discharge measurements and data analysis were conducted by the USGS. Total nitrogen concentrations were lower in Davenport Branch than in Long Swamp Creek and Wrangle Brook during base flow and stormflow. Concentrations of total nitrogen and nitrate were highest in Wrangle Brook (as high as 3.0 mg/L and 1.6 mg/L, respectively) as a result of high concentrations of nitrate in samples collected during base flow; nitrate loading from ground-water discharge is much higher in Wrangle Brook than in any of the other streams, possibly as a result of an experimental wastewater-(secondary effluent) disposal site that was in operation during the 1980's. Ammonia concentrations were higher in samples from Long Swamp Creek than in those from the other two monitoring sites under all flow conditions, and ammonia yields were higher during stormflow than base flow at all monitoring sites. Concentrations and yields of fecal coliform bacteria and total suspended solids were higher during stormflow than during base flow at all monitoring sites. Concentrations and yields were significantly higher in Long Swamp Creek, a highly developed subbasin and Wrangle Brook, a moderately developed subbasin than in Davenport Branch, a slightly developed subbasin. Concentrations and yields of phosphate species, which also are strongly related to stormflow, were higher during stormflow in Long Swamp Creek than in the other subbasins. Base-flow separation techniques were used on hydrographs generated for storms to distinguish the fraction of discharge and constituent loading attributable to storm runoff (overland flow) from the fraction contributed by ground-water discharge. Precipitation records were used to determine the total annual volumes of ground-water discharge and runoff at each monitoring site. These volumes were used in conjunction with water-quality data to calculate total annual loads of each constituent at each monitoring site, separated into ground-water discharge and runoff fractions. It was determined that loads of ammonia, nitrate, organic nitrogen, total nitrogen, and orthophosphate in ground-water discharge were significantly higher in the moderately developed Wrangle Brook subbasin than in the highly developed Long Swamp Creek subbasin, and that no relation was apparent between the percent of land development and constituent loads from ground-water discharge. The loading of each constituent contributed by ground-water discharge is specific

High resolution modelling of extreme precipitation events in urban areas

NASA Astrophysics Data System (ADS)

Siemerink, Martijn; Volp, Nicolette; Schuurmans, Wytze; Deckers, Dave

2015-04-01

The present day society needs to adjust to the effects of climate change. More extreme weather conditions are expected, which can lead to longer periods of drought, but also to more extreme precipitation events. Urban water systems are not designed for such extreme events. Most sewer systems are not able to drain the excessive storm water, causing urban flooding. This leads to high economic damage. In order to take appropriate measures against extreme urban storms, detailed knowledge about the behaviour of the urban water system above and below the streets is required. To investigate the behaviour of urban water systems during extreme precipitation events new assessment tools are necessary. These tools should provide a detailed and integral description of the flow in the full domain of overland runoff, sewer flow, surface water flow and groundwater flow. We developed a new assessment tool, called 3Di, which provides detailed insight in the urban water system. This tool is based on a new numerical methodology that can accurately deal with the interaction between overland runoff, sewer flow and surface water flow. A one-dimensional model for the sewer system and open channel flow is fully coupled to a two-dimensional depth-averaged model that simulates the overland flow. The tool uses a subgrid-based approach in order to take high resolution information of the sewer system and of the terrain into account [1, 2]. The combination of using the high resolution information and the subgrid based approach results in an accurate and efficient modelling tool. It is now possible to simulate entire urban water systems using extreme high resolution (0.5m x 0.5m) terrain data in combination with a detailed sewer and surface water network representation. The new tool has been tested in several Dutch cities, such as Rotterdam, Amsterdam and The Hague. We will present the results of an extreme precipitation event in the city of Schiedam (The Netherlands). This city deals with significant soil consolidation and the low-lying areas are prone to urban flooding. The simulation results are compared with measurements in the sewer network. References [1] Guus S. Stelling G.S., 2012. Quadtree flood simulations with subgrid digital elevation models. Water Management 165 (WM1):1329-1354. [2] Vincenzo Cassuli and Guus S. Stelling, 2013. A semi-implicit numerical model for urban drainage systems. International Journal for Numerical Methods in Fluids. Vol. 73:600-614. DOI: 10.1002/fld.3817

Flow field analysis of high-speed helium turboexpander for cryogenic refrigeration and liquefaction cycles

NASA Astrophysics Data System (ADS)

Sam, Ashish Alex; Ghosh, Parthasarathi

2017-03-01

Turboexpander constitutes one of the vital components of Claude cycle based helium refrigerators and liquefiers that are gaining increasing technological importance. These turboexpanders which are of radial inflow in configuration are generally high-speed micro turbines, due to the low molecular weight and density of helium. Any improvement in efficiency of these machines requires a detailed understanding of the flow field. Computational Fluid Dynamics analysis (CFD) has emerged as a necessary tool for the determination of the flow fields in cryogenic turboexpanders, which is often not possible through experiments. In the present work three-dimensional transient flow analysis of a cryogenic turboexpander for helium refrigeration and liquefaction cycles were performed using Ansys CFX®, to understand the flow field of a high-speed helium turboexpander, which in turn will help in taking appropriate decisions regarding modifications of established design methodology for improved efficiency of these machines. The turboexpander is designed based on Balje's nsds diagram and the inverse design blade profile generation formalism prescribed by Hasselgruber and Balje. The analyses include the study of several losses, their origins, the increase in entropy due to these losses, quantification of losses and the effects of various geometrical parameters on these losses. Through the flow field analysis it was observed that in the nozzle, flow separation at the nozzle blade suction side and trailing edge vortices resulted in loss generation, which calls for better nozzle blade profile. The turbine wheel flow field analysis revealed that the significant geometrical parameters of the turbine wheel blade like blade inlet angle, blade profile, tip clearance height and trailing edge thickness need to be optimised for improved performance of the turboexpander. The detailed flow field analysis in this paper can be used to improve the mean line design methodology for turboexpanders used in helium refrigeration and liquefaction cycles.

Projected Changes in Hydrological Extremes in a Cold Region Watershed: Sensitivity of Results to Statistical Methods of Analysis

NASA Astrophysics Data System (ADS)

Dibike, Y. B.; Eum, H. I.; Prowse, T. D.

2017-12-01

Flows originating from alpine dominated cold region watersheds typically experience extended winter low flows followed by spring snowmelt and summer rainfall driven high flows. In a warmer climate, there will be temperature- induced shift in precipitation from snow towards rain as well as changes in snowmelt timing affecting the frequency of extreme high and low flow events which could significantly alter ecosystem services. This study examines the potential changes in the frequency and severity of hydrologic extremes in the Athabasca River watershed in Alberta, Canada based on the Variable Infiltration Capacity (VIC) hydrologic model and selected and statistically downscaled climate change scenario data from the latest Coupled Model Intercomparison Project (CMIP5). The sensitivity of these projected changes is also examined by applying different extreme flow analysis methods. The hydrological model projections show an overall increase in mean annual streamflow in the watershed and a corresponding shift in the freshet timing to earlier period. Most of the streams are projected to experience increases during the winter and spring seasons and decreases during the summer and early fall seasons, with an overall projected increases in extreme high flows, especially for low frequency events. While the middle and lower parts of the watershed are characterised by projected increases in extreme high flows, the high elevation alpine region is mainly characterised by corresponding decreases in extreme low flow events. However, the magnitude of projected changes in extreme flow varies over a wide range, especially for low frequent events, depending on the climate scenario and period of analysis, and sometimes in a nonlinear way. Nonetheless, the sensitivity of the projected changes to the statistical method of analysis is found to be relatively small compared to the inter-model variability.

The flow dynamics of an extremely large volume pyroclastic flow, the 2.08-Ma Cerro Galán Ignimbrite, NW Argentina, and comparison with other flow types

USGS Publications Warehouse

Cas, Ray A.F.; Wright, Heather M.; Folkes, Christopher B.; Lesti, Chiara; Porreca, Massimiliano; Giordano, Guido; Viramonte, Jose G.

2011-01-01

The 2.08-Ma Cerro Galán Ignimbrite (CGI) represents a >630-km3 dense rock equivalent (VEI 8) eruption from the long-lived Cerro Galán magma system (∼6 Ma). It is a crystal-rich (35–60%), pumice (<10% generally) and lithic-poor (<5% generally) rhyodacitic ignimbrite, lacking a preceding plinian fallout deposit. The CGI is preserved up to 80 km from the structural margins of the caldera, but almost certainly was deposited up to 100 km from the caldera in some places. Only one emplacement unit is preserved in proximal to medial settings and in most distal settings, suggesting constant flow conditions, but where the pyroclastic flow moved into a palaeotopography of substantial valleys and ridges, it interacted with valley walls, resulting in flow instabilities that generated multiple depositional units, often separated by pyroclastic surge deposits. The CGI preserves a widespread sub-horizontal fabric, defined by aligned elongate pumice and lithic clasts, and minerals (e.g. biotite). A sub-horizontal anisotropy of magnetic susceptibility fabric is defined by minute magnetic minerals in all localities where it has been analysed. The CGI is poor in both vent-derived (‘accessory’) lithics and locally derived lithics from the ground surface (‘accidental’) lithics. Locally derived lithics are small (<20 cm) and were not transported far from source points. All data suggest that the pyroclastic flow system producing the CGI was characterised throughout by high sedimentation rates, resulting from high particle concentration and suppressed turbulence at the depositional boundary layer, despite being a low aspect ratio ignimbrite. Based on these features, we question whether high velocity and momentum are necessary to account for extensive flow mobility. It is proposed that the CGI was deposited by a pyroclastic flow system that developed a substantial, high particle concentration granular under-flow, which flowed with suppressed turbulence. High particle concentration and fine-ash content hindered gas loss and maintained flow mobility. In order to explain the contemporaneous maintenance of high particle concentration, high sedimentation rate at the depositional boundary layer and a high level of mobility, it is also proposed that the flow(s) was continuously supplied at a high mass feeding rate. It is also proposed that internal gas pressure within the flow, directed downwards onto the substrate over which the flow was passing, reduced the friction between the flow and the substrate and also enhanced its mobility. The pervasive sub-horizontal fabric of aligned pumice, lithic and even biotite crystals indicates a consistent horizontal shear force existed during transport and deposition in the basal granular flow, consistent with the existence of a laminar, shearing, granular flow regime during the final stages of transport and deposition.

Temporal Large-Eddy Simulation

NASA Technical Reports Server (NTRS)

Pruett, C. D.; Thomas, B. C.

2004-01-01

In 1999, Stolz and Adams unveiled a subgrid-scale model for LES based upon approximately inverting (defiltering) the spatial grid-filter operator and termed .the approximate deconvolution model (ADM). Subsequently, the utility and accuracy of the ADM were demonstrated in a posteriori analyses of flows as diverse as incompressible plane-channel flow and supersonic compression-ramp flow. In a prelude to the current paper, a parameterized temporal ADM (TADM) was developed and demonstrated in both a priori and a posteriori analyses for forced, viscous Burger's flow. The development of a time-filtered variant of the ADM was motivated-primarily by the desire for a unifying theoretical and computational context to encompass direct numerical simulation (DNS), large-eddy simulation (LES), and Reynolds averaged Navier-Stokes simulation (RANS). The resultant methodology was termed temporal LES (TLES). To permit exploration of the parameter space, however, previous analyses of the TADM were restricted to Burger's flow, and it has remained to demonstrate the TADM and TLES methodology for three-dimensional flow. For several reasons, plane-channel flow presents an ideal test case for the TADM. Among these reasons, channel flow is anisotropic, yet it lends itself to highly efficient and accurate spectral numerical methods. Moreover, channel-flow has been investigated extensively by DNS, and a highly accurate data base of Moser et.al. exists. In the present paper, we develop a fully anisotropic TADM model and demonstrate its utility in simulating incompressible plane-channel flow at nominal values of Re(sub tau) = 180 and Re(sub tau) = 590 by the TLES method. The TADM model is shown to perform nearly as well as the ADM at equivalent resolution, thereby establishing TLES as a viable alternative to LES. Moreover, as the current model is suboptimal is some respects, there is considerable room to improve TLES.

Ground-based LiDAR Measurements of Actively Inflating Pahoehoe Flows, Kilauea Volcano, Hawaii: Implications for Emplacement of Basaltic Units on Mars

NASA Astrophysics Data System (ADS)

Byrnes, J. M.; Finnegan, D. C.; Nicoll, K.; Anderson, S. W.

2007-05-01

Remote sensing datasets enable planetary volcanologists to extract information regarding eruption processes. Long-lived effusive eruptions at sites such as Kilauea Volcano (HI) provide opportunities to collect rich observational data sets, including detailed measurements of topography and extrusion rates, that allow comparisons between lava flow surface morphologies and emplacement conditions for use in interpreting similar morphological features associated with planetary lava flows. On Mars, the emplacement of basaltic lava flows is a volumetrically and spatially important process, creating both large-scale and small-scale surface morphologies. On Earth, low effusion rate eruptions on relatively horizontal slopes tend to create inflated lava flows that display hummocky topography. To better understand the processes involved in creating observed surface characteristics, we repeatedly measured the surface topography of an actively flowing and inflating basaltic unit within the Pu'u O'o flow field over a 5-day period. We used a ground-based laser-scanner (LiDAR) system that provided vertical and horizontal accuracies of 4 mm. Comparing DEMs from repeated laser scans yielded the magnitudes and styles of constructional processes, allowing us to quantify the relationship between pre- and post-emplacement surface topography. Our study site (roughly 200 m x 200 m) experienced about 5 m of vertical inflation over a 3 day period and created a new hummocky surface containing several tumuli. The temporal and spatial patterns of inflation were complex and showed no obvious relationship with underlying topography. High-precision morphometric measurements acquired using ground-based LiDAR affords us the opportunity to capture the essential boundary conditions necessary for evaluating and comparing high-resolution planetary data sets, such as those acquired by the MOC, HRSC, and HiRISE instruments.

Towards designing an optical-flow based colonoscopy tracking algorithm: a comparative study

NASA Astrophysics Data System (ADS)

Liu, Jianfei; Subramanian, Kalpathi R.; Yoo, Terry S.

2013-03-01

Automatic co-alignment of optical and virtual colonoscopy images can supplement traditional endoscopic procedures, by providing more complete information of clinical value to the gastroenterologist. In this work, we present a comparative analysis of our optical flow based technique for colonoscopy tracking, in relation to current state of the art methods, in terms of tracking accuracy, system stability, and computational efficiency. Our optical-flow based colonoscopy tracking algorithm starts with computing multi-scale dense and sparse optical flow fields to measure image displacements. Camera motion parameters are then determined from optical flow fields by employing a Focus of Expansion (FOE) constrained egomotion estimation scheme. We analyze the design choices involved in the three major components of our algorithm: dense optical flow, sparse optical flow, and egomotion estimation. Brox's optical flow method,1 due to its high accuracy, was used to compare and evaluate our multi-scale dense optical flow scheme. SIFT6 and Harris-affine features7 were used to assess the accuracy of the multi-scale sparse optical flow, because of their wide use in tracking applications; the FOE-constrained egomotion estimation was compared with collinear,2 image deformation10 and image derivative4 based egomotion estimation methods, to understand the stability of our tracking system. Two virtual colonoscopy (VC) image sequences were used in the study, since the exact camera parameters(for each frame) were known; dense optical flow results indicated that Brox's method was superior to multi-scale dense optical flow in estimating camera rotational velocities, but the final tracking errors were comparable, viz., 6mm vs. 8mm after the VC camera traveled 110mm. Our approach was computationally more efficient, averaging 7.2 sec. vs. 38 sec. per frame. SIFT and Harris affine features resulted in tracking errors of up to 70mm, while our sparse optical flow error was 6mm. The comparison among egomotion estimation algorithms showed that our FOE-constrained egomotion estimation method achieved the optimal balance between tracking accuracy and robustness. The comparative study demonstrated that our optical-flow based colonoscopy tracking algorithm maintains good accuracy and stability for routine use in clinical practice.

High pressure die casting of Fe-based metallic glass.

PubMed

Ramasamy, Parthiban; Szabo, Attila; Borzel, Stefan; Eckert, Jürgen; Stoica, Mihai; Bárdos, András

2016-10-11

Soft ferromagnetic Fe-based bulk metallic glass key-shaped specimens with a maximum and minimum width of 25.4 and 5 mm, respectively, were successfully produced using a high pressure die casting (HPDC) method, The influence of die material, alloy temperature and flow rate on the microstructure, thermal stability and soft ferromagnetic properties has been studied. The results suggest that a steel die in which the molten metal flows at low rate and high temperature can be used to produce completely glassy samples. This can be attributed to the laminar filling of the mold and to a lower heat transfer coefficient, which avoids the skin effect in the steel mold. In addition, magnetic measurements reveal that the amorphous structure of the material is maintained throughout the key-shaped samples. Although it is difficult to control the flow and cooling rate of the molten metal in the corners of the key due to different cross sections, this can be overcome by proper tool geometry. The present results confirm that HPDC is a suitable method for the casting of Fe-based bulk glassy alloys even with complex geometries for a broad range of applications.

High pressure die casting of Fe-based metallic glass

NASA Astrophysics Data System (ADS)

Ramasamy, Parthiban; Szabo, Attila; Borzel, Stefan; Eckert, Jürgen; Stoica, Mihai; Bárdos, András

2016-10-01

Soft ferromagnetic Fe-based bulk metallic glass key-shaped specimens with a maximum and minimum width of 25.4 and 5 mm, respectively, were successfully produced using a high pressure die casting (HPDC) method, The influence of die material, alloy temperature and flow rate on the microstructure, thermal stability and soft ferromagnetic properties has been studied. The results suggest that a steel die in which the molten metal flows at low rate and high temperature can be used to produce completely glassy samples. This can be attributed to the laminar filling of the mold and to a lower heat transfer coefficient, which avoids the skin effect in the steel mold. In addition, magnetic measurements reveal that the amorphous structure of the material is maintained throughout the key-shaped samples. Although it is difficult to control the flow and cooling rate of the molten metal in the corners of the key due to different cross sections, this can be overcome by proper tool geometry. The present results confirm that HPDC is a suitable method for the casting of Fe-based bulk glassy alloys even with complex geometries for a broad range of applications.

High pressure die casting of Fe-based metallic glass

PubMed Central

Ramasamy, Parthiban; Szabo, Attila; Borzel, Stefan; Eckert, Jürgen; Stoica, Mihai; Bárdos, András

2016-01-01

Soft ferromagnetic Fe-based bulk metallic glass key-shaped specimens with a maximum and minimum width of 25.4 and 5 mm, respectively, were successfully produced using a high pressure die casting (HPDC) method, The influence of die material, alloy temperature and flow rate on the microstructure, thermal stability and soft ferromagnetic properties has been studied. The results suggest that a steel die in which the molten metal flows at low rate and high temperature can be used to produce completely glassy samples. This can be attributed to the laminar filling of the mold and to a lower heat transfer coefficient, which avoids the skin effect in the steel mold. In addition, magnetic measurements reveal that the amorphous structure of the material is maintained throughout the key-shaped samples. Although it is difficult to control the flow and cooling rate of the molten metal in the corners of the key due to different cross sections, this can be overcome by proper tool geometry. The present results confirm that HPDC is a suitable method for the casting of Fe-based bulk glassy alloys even with complex geometries for a broad range of applications. PMID:27725780

Flow Effects on the Flammability Diagrams of Solid Fuels

NASA Technical Reports Server (NTRS)

Cordova, J. L.; Ceamanos, J.; Fernandez-Pello, A. C.; Long, R. T.; Torero, J. L.; Quintiere, J. G.

1997-01-01

A research program is currently underway with the final objective of developing a fundamental understanding of the controlling mechanisms underlying the flammability diagrams of solid combustible materials and their derived fire properties. Given that there is a high possibility of an accidental fire occurring in a space-based facility, understanding the fire properties of materials that will be used in such facilities is of critical importance. With this purpose, the flammability diagrams of the materials, as those produced by the Lateral Ignition and Flame Spread Test (LIFT) apparatus and by a new forced flow device, the Forced Flow Ignition and Flame Spread Test (FIST) apparatus, will be obtained. The specific objective of the program is to apply the new flammability apparatus, which will more accurately reflect the potential ambient conditions of space-based environments, to the characterization of the materials for space applications. This paper presents a parametric study of oxidizer flow effects on the ignition curve of the flammability diagrams of PMMA. The dependence of the ignition delay time on the external radiant flux and either the sample width (LIFT) or the flow velocity (FIST) has been studied. Although preliminary, the results indicate that natural and forced convection flow changes, affect the characteristics of the ignition curves of the flammability diagrams. The major effect on the ignition time appears to be due to convective transfer variations at the fuel surface. At high radiant fluxes or high flow velocities, however, it appears that gas phase processes become increasingly important, affecting the overall ignition delay time. A numerical analysis of the solid fuel heating and pyrolysis has also been developed. The theoretical predictions approximate the experiments well for conditions in which the gas phase induction time is negligible.

Density-based global sensitivity analysis of sheet-flow travel time: Kinematic wave-based formulations

NASA Astrophysics Data System (ADS)

Hosseini, Seiyed Mossa; Ataie-Ashtiani, Behzad; Simmons, Craig T.

2018-04-01

Despite advancements in developing physics-based formulations to estimate the sheet-flow travel time (tSHF), the quantification of the relative impacts of influential parameters on tSHF has not previously been considered. In this study, a brief review of the physics-based formulations to estimate tSHF including kinematic wave (K-W) theory in combination with Manning's roughness (K-M) and with Darcy-Weisbach friction formula (K-D) over single and multiple planes is provided. Then, the relative significance of input parameters to the developed approaches is quantified by a density-based global sensitivity analysis (GSA). The performance of K-M considering zero-upstream and uniform flow depth (so-called K-M1 and K-M2), and K-D formulae to estimate the tSHF over single plane surface were assessed using several sets of experimental data collected from the previous studies. The compatibility of the developed models to estimate tSHF over multiple planes considering temporal rainfall distributions of Natural Resources Conservation Service, NRCS (I, Ia, II, and III) are scrutinized by several real-world examples. The results obtained demonstrated that the main controlling parameters of tSHF through K-D and K-M formulae are the length of surface plane (mean sensitivity index T̂i = 0.72) and flow resistance (mean T̂i = 0.52), respectively. Conversely, the flow temperature and initial abstraction ratio of rainfall have the lowest influence on tSHF (mean T̂i is 0.11 and 0.12, respectively). The significant role of the flow regime on the estimation of tSHF over a single and a cascade of planes are also demonstrated. Results reveal that the K-D formulation provides more precise tSHF over the single plane surface with an average percentage of error, APE equal to 9.23% (the APE for K-M1 and K-M2 formulae were 13.8%, and 36.33%, respectively). The superiority of Manning-jointed formulae in estimation of tSHF is due to the incorporation of effects from different flow regimes as flow moves downgradient that is affected by one or more factors including high excess rainfall intensities, low flow resistance, high degrees of imperviousness, long surfaces, steep slope, and domination of rainfall distribution as NRCS Type I, II, or III.

Base flow investigation of the Apollo AS-202 Command Module

NASA Astrophysics Data System (ADS)

Walpot, Louis M. G.; Wright, Michael J.; Noeding, Peter; Schrijer, Ferry

2012-01-01

A major contributor to the overall vehicle mass of re-entry vehicles is the afterbody thermal protection system. This is due to the large acreage (equal or bigger than that of the forebody) to be protected. The present predictive capabilities for base flows are comparatively lower than those for windward flowfields and offer therefore a substantial potential for improving the design of future re-entry vehicles. To that end, it is essential to address the accuracy of high fidelity CFD tools exercised in the US and EU, which motivates a thorough investigation of the present status of hypersonic flight afterbody heating. This paper addresses the predictive capabilities of afterbody flow fields of re-entry vehicles investigated in the frame of the NATO/RTO-RTG-043 task group. First, the verification of base flow topologies on the basis of available wind-tunnel results performed under controlled supersonic conditions (i.e. cold flows devoid of reactive effects) is performed. Such tests address the detailed characterization of the base flow with particular emphasis on separation/reattachment and their relation to Mach number effects. The tests have been performed on an Apollo-like re-entry capsule configuration. Second, the tools validated in the frame of the previous effort are exercised and appraised against flight-test data collected during the Apollo AS-202 re-entry.

Co-Flow Hollow Cathode Technology

NASA Technical Reports Server (NTRS)

Hofer, Richard R.; Goebel, Dan M.

2011-01-01

Hall thrusters utilize identical hollow cathode technology as ion thrusters, yet must operate at much higher mass flow rates in order to efficiently couple to the bulk plasma discharge. Higher flow rates are necessary in order to provide enough neutral collisions to transport electrons across magnetic fields so that they can reach the discharge. This higher flow rate, however, has potential life-limiting implications for the operation of the cathode. A solution to the problem involves splitting the mass flow into the hollow cathode into two streams, the internal and external flows. The internal flow is fixed and set such that the neutral pressure in the cathode allows for a high utilization of the emitter surface area. The external flow is variable depending on the flow rate through the anode of the Hall thruster, but also has a minimum in order to suppress high-energy ion generation. In the co-flow hollow cathode, the cathode assembly is mounted on thruster centerline, inside the inner magnetic core of the thruster. An annular gas plenum is placed at the base of the cathode and propellant is fed throughout to produce an azimuthally symmetric flow of gas that evenly expands around the cathode keeper. This configuration maximizes propellant utilization and is not subject to erosion processes. External gas feeds have been considered in the past for ion thruster applications, but usually in the context of eliminating high energy ion production. This approach is adapted specifically for the Hall thruster and exploits the geometry of a Hall thruster to feed and focus the external flow without introducing significant new complexity to the thruster design.

The effects of Missouri River mainstem reservoir system operations on 2011 flooding using a Precipitation-Runoff Modeling System model: Chapter K in 2011 Floods of the Central United States

USGS Publications Warehouse

Haj, Adel E.; Christiansen, Daniel E.; Viger, Roland J.

2014-01-01

In 2011 the Missouri River Mainstem Reservoir System (Reservoir System) experienced the largest volume of flood waters since the initiation of record-keeping in the nineteenth century. The high levels of runoff from both snowpack and rainfall stressed the Reservoir System’s capacity to control flood waters and caused massive damage and disruption along the river. The flooding and resulting damage along the Missouri River brought increased public attention to the U.S. Army Corps of Engineers (USACE) operation of the Reservoir System. To help understand the effects of Reservoir System operation on the 2011 Missouri River flood flows, the U.S. Geological Survey Precipitation-Runoff Modeling System was used to construct a model of the Missouri River Basin to simulate flows at streamgages and dam locations with the effects of Reservoir System operation (regulation) on flow removed. Statistical tests indicate that the Missouri River Precipitation-Runoff Modeling System model is a good fit for high-flow monthly and annual stream flow estimation. A comparison of simulated unregulated flows and measured regulated flows show that regulation greatly reduced spring peak flow events, consolidated two summer peak flow events to one with a markedly decreased magnitude, and maintained higher than normal base flow beyond the end of water year 2011. Further comparison of results indicate that without regulation, flows greater than those measured would have occurred and been sustained for much longer, frequently in excess of 30 days, and flooding associated with high-flow events would have been more severe.

Next Generation Flow for highly sensitive and standardized detection of minimal residual disease in multiple myeloma.

PubMed

Flores-Montero, J; Sanoja-Flores, L; Paiva, B; Puig, N; García-Sánchez, O; Böttcher, S; van der Velden, V H J; Pérez-Morán, J-J; Vidriales, M-B; García-Sanz, R; Jimenez, C; González, M; Martínez-López, J; Corral-Mateos, A; Grigore, G-E; Fluxá, R; Pontes, R; Caetano, J; Sedek, L; Del Cañizo, M-C; Bladé, J; Lahuerta, J-J; Aguilar, C; Bárez, A; García-Mateo, A; Labrador, J; Leoz, P; Aguilera-Sanz, C; San-Miguel, J; Mateos, M-V; Durie, B; van Dongen, J J M; Orfao, A

2017-10-01

Flow cytometry has become a highly valuable method to monitor minimal residual disease (MRD) and evaluate the depth of complete response (CR) in bone marrow (BM) of multiple myeloma (MM) after therapy. However, current flow-MRD has lower sensitivity than molecular methods and lacks standardization. Here we report on a novel next generation flow (NGF) approach for highly sensitive and standardized MRD detection in MM. An optimized 2-tube 8-color antibody panel was constructed in five cycles of design-evaluation-redesign. In addition, a bulk-lysis procedure was established for acquisition of ⩾10 7 cells/sample, and novel software tools were constructed for automatic plasma cell gating. Multicenter evaluation of 110 follow-up BM from MM patients in very good partial response (VGPR) or CR showed a higher sensitivity for NGF-MRD vs conventional 8-color flow-MRD -MRD-positive rate of 47 vs 34% (P=0.003)-. Thus, 25% of patients classified as MRD-negative by conventional 8-color flow were MRD-positive by NGF, translating into a significantly longer progression-free survival for MRD-negative vs MRD-positive CR patients by NGF (75% progression-free survival not reached vs 7 months; P=0.02). This study establishes EuroFlow-based NGF as a highly sensitive, fully standardized approach for MRD detection in MM which overcomes the major limitations of conventional flow-MRD methods and is ready for implementation in routine diagnostics.

A fiber-optic water flow sensor based on laser-heated silicon Fabry-Pérot cavity

NASA Astrophysics Data System (ADS)

Liu, Guigen; Sheng, Qiwen; Resende Lisboa Piassetta, Geraldo; Hou, Weilin; Han, Ming

2016-05-01

A hot-wire fiber-optic water flow sensor based on laser-heated silicon Fabry-Pérot interferometer (FPI) has been proposed and demonstrated in this paper. The operation of the sensor is based on the convective heat loss to water from a heated silicon FPI attached to the cleaved enface of a piece of single-mode fiber. The flow-induced change in the temperature is demodulated by the spectral shifts of the reflection fringes. An analytical model based on the FPI theory and heat transfer analysis has been developed for performance analysis. Numerical simulations based on finite element analysis have been conducted. The analytical and numerical results agree with each other in predicting the behavior of the sensor. Experiments have also been carried to demonstrate the sensing principle and verify the theoretical analysis. Investigations suggest that the sensitivity at low flow rates are much larger than that at high flow rates and the sensitivity can be easily improved by increasing the heating laser power. Experimental results show that an average sensitivity of 52.4 nm/(m/s) for the flow speed range of 1.5 mm/s to 12 mm/s was obtained with a heating power of ~12 mW, suggesting a resolution of ~1 μm/s assuming a wavelength resolution of 0.05 pm.

Assessment of nonequilibrium radiation computation methods for hypersonic flows

NASA Technical Reports Server (NTRS)

Sharma, Surendra

1993-01-01

The present understanding of shock-layer radiation in the low density regime, as appropriate to hypersonic vehicles, is surveyed. Based on the relative importance of electron excitation and radiation transport, the hypersonic flows are divided into three groups: weakly ionized, moderately ionized, and highly ionized flows. In the light of this division, the existing laboratory and flight data are scrutinized. Finally, an assessment of the nonequilibrium radiation computation methods for the three regimes in hypersonic flows is presented. The assessment is conducted by comparing experimental data against the values predicted by the physical model.

Numerical analysis of base flowfield at high altitude for a four-engine clustered nozzle configuration

NASA Technical Reports Server (NTRS)

Wang, Ten-See

1993-01-01

The objective of this study is to benchmark a four-engine clustered nozzle base flowfield with a computational fluid dynamics (CFD) model. The CFD model is a pressure based, viscous flow formulation. An adaptive upwind scheme is employed for the spatial discretization. The upwind scheme is based on second and fourth order central differencing with adaptive artificial dissipation. Qualitative base flow features such as the reverse jet, wall jet, recompression shock, and plume-plume impingement have been captured. The computed quantitative flow properties such as the radial base pressure distribution, model centerline Mach number and static pressure variation, and base pressure characteristic curve agreed reasonably well with those of the measurement. Parametric study on the effect of grid resolution, turbulence model, inlet boundary condition and difference scheme on convective terms has been performed. The results showed that grid resolution and turbulence model are two primary factors that influence the accuracy of the base flowfield prediction.

High Precision 40Ar/39Ar Geochronology of Servilleta Basalts of the Rio Grande Gorge, New Mexico

NASA Astrophysics Data System (ADS)

Cosca, M. A.; Thompson, R. A.; Turner, K. J.

2014-12-01

New geologic mapping and high-precision 40Ar/39Ar geochronology within the Taos Plateau in northern New Mexico indicate a period of vigorous volcanic activity between ~5.5 and ~1 Ma. Over 50 visible volcanic centers formed during this time together with an unresolved number of vents, fissures, and volcanic centers buried by intercalated volcanic rock and sedimentary basin fill. Defining the volcanic stratigraphy is essential for models of regional groundwater flow and for understanding the geologic evolution of the Pliocene to Recent Rio Grande rift. A spectacular stratigraphic section of volcanic rock related to Rio Grande rifting is visible from the High Bridge, just a few miles outside of Taos, NM, where a 240 m canyon is incised through the basal, middle, and upper Servilleta basalt flow packages (Dungan et al., 1984). Fresh basalt from a vertical transect of the canyon near the High Bridge were analyzed by 40Ar/39Ar methods on ~3 mm3 rock fragments using an ARGUS VI mass spectrometer and the resulting 40Ar/39Ar ages define a precise emplacement chronology of the entire stratigraphic section. The basal flow package records ages of 4.78 ± 0.03 Ma (relative to FCT sanidine = 28.204 Ma; all errors 2 sigma) at river level, 4.77 ± 0.03 Ma at mid flow, and 4.50 ± 0.04 Ma at the top of the flow. The middle flow package records ages of 4.11 ± 0.03 Ma at the base of the flow, 4.08 ± 0.04 Ma mid flow, and 4.02 ± 0.06 Ma at the top of the flow. The upper basalt package records ages of 3.69 ± 0.06 Ma at the base of the flow and 3.59 ± 0.08 Ma at the top of the flow. These data support rapid effusion of voluminous lava flows on time scales of 100-200 ka. Two reddish paleosols separating the Servilleta packages each developed during a 400 ka period of volcanic quiescence. First order calculations using exposed lava thicknesses in the gorge and areal exposures suggest each flow package represents emplacement of ~200 km3 of basalt. Because no exposed vent of appropriate age has been identified that could produce such basalt volumes, the Servilleta basalts probably erputed from buried vents and/or fissures, possibly oriented along the northwest trending fault systems defining the Rio Grande rift graben.

Base-flow characteristics of streams in the Valley and Ridge, Blue Ridge, and Piedmont physiographic provinces of Virginia

USGS Publications Warehouse

Nelms, D.L.; Harlow, G.E.; Hayes, Donald C.

1995-01-01

Growth within the Valley and Ridge, Blue Ridge, and Piedmont Physiographic Provinces of Virginia has focussed concern about allocation of surface-water flow and increased demands on the ground-water resources. The purpose of this report is to (1) describe the base-flow characteristics of streams, (2) identify regional differences in these flow characteristics, and (3) describe, if possible, the potential surface-water and ground-water yields of basins on the basis of the base-flow character- istics. Base-flow characteristics are presented for streams in the Valley and Ridge, Blue Ridge, and Piedmont Physiographic Provinces of Virginia. The provinces are separated into five regions: (1) Valley and Ridge, (2) Blue Ridge, (3) Piedmont/Blue Ridge transition, (4) Piedmont northern, and (5) Piedmont southern. Different flow statistics, which represent streamflows predominantly comprised of base flow, were determined for 217 continuous-record streamflow-gaging stations from historical mean daily discharge and for 192 partial-record streamflow-gaging stations by means of correlation of discharge measurements. Variability of base flow is represented by a duration ratio developed during this investigation. Effective recharge rates were also calculated. Median values for the different flow statistics range from 0.05 cubic foot per second per square mile for the 90-percent discharge on the streamflow-duration curve to 0.61 cubic foot per second per square mile for mean base flow. An excellent estimator of mean base flow for the Piedmont/Blue Ridge transition region and Piedmont southern region is the 50-percent discharge on the streamflow-duration curve, but tends to under- estimate mean base flow for the remaining regions. The base-flow variability index ranges from 0.07 to 2.27, with a median value of 0.55. Effective recharge rates range from 0.07 to 33.07 inches per year, with a median value of 8.32 inches per year. Differences in the base-flow characteristics exist between regions. The median discharges for the Valley and Ridge, Blue Ridge, and Piedmont/Blue Ridge transition regions are higher than those for the Piedmont regions. Results from statistical analysis indicate that the regions can be ranked in terms of base-flow characteristics from highest to lowest as follows: (1) Piedmont/Blue Ridge transition, (2) Valley and Ridge and Blue Ridge, (3) Piedmont southern, and (4) Piedmont northern. The flow statistics are consistently higher and the values for base-flow variability are lower for basins within the Piedmont/Blue Ridge transition region relative to those from the other regions, whereas the basins within the Piedmont northern region show the opposite pattern. The group rankings of the base-flow characteristics were used to designate the potential surface-water yield for the regions. In addition, an approach developed for this investigation assigns a rank for potential surface- water yield to a basin according to the quartiles in which the values for the base-flow character- istics are located. Both procedures indicate that the Valley and Ridge, Blue Ridge, and Piedmont/Blue Ridge transition regions have moderate-to-high potential surface-water yield and the Piedmont regions have low-to-moderate potential surface- water yield. In order to indicate potential ground-water yield from base-flow characteristics, aquifer properties for 51 streamflow-gaging stations with continuous record of streamflow data were determined by methods that use streamflow records and basin characteristics. Areal diffusivity ranges from 17,100 to 88,400 feet squared per day, with a median value of 38,400 feet squared per day. Areal transmissivity ranges from 63 to 830 feet squared per day, with a median value of 270 feet squared per day. Storage coefficients, which were estimated by dividing areal transmissivity by areal diffusivity, range from approximately 0.001 to 0.019 (dimensionless), with a median value of 0.007. The median value for areal diffus

Discrete sonic jets used as boundary-layer trips at Mach numbers of 6 and 8.5

NASA Technical Reports Server (NTRS)

Stone, D. R.; Cary, A. M., Jr.

1972-01-01

The effect of discrete three-dimensional sonic jets used to promote transition on a sharp-leading-edge flat plate at Mach numbers of 6 and 8.5 and unit Reynolds numbers as high as 2.5 x 100,000 per cm in the Langley 20-inch hypersonic tunnels is discussed. An examination of the downstream flow-field distortions associated with the discrete jets for the Mach 8.5 flow was also conducted. Jet trips are found to produce lengths of turbulent flow comparable to those obtained for spherical-roughness-element trips while significantly reducing the downstream flow distortions. A Reynolds number based upon secondary jet penetration into a supersonic main flow is used to correlate jet-trip effectiveness just as a Reynolds number based upon roughness height is used to correlate spherical-trip effectiveness. Measured heat-transfer data are in agreement with the predictions.

A radial flow microfluidic device for ultra-high-throughput affinity-based isolation of circulating tumor cells.

PubMed

Murlidhar, Vasudha; Zeinali, Mina; Grabauskiene, Svetlana; Ghannad-Rezaie, Mostafa; Wicha, Max S; Simeone, Diane M; Ramnath, Nithya; Reddy, Rishindra M; Nagrath, Sunitha

2014-12-10

Circulating tumor cells (CTCs) are believed to play an important role in metastasis, a process responsible for the majority of cancer-related deaths. But their rarity in the bloodstream makes microfluidic isolation complex and time-consuming. Additionally the low processing speeds can be a hindrance to obtaining higher yields of CTCs, limiting their potential use as biomarkers for early diagnosis. Here, a high throughput microfluidic technology, the OncoBean Chip, is reported. It employs radial flow that introduces a varying shear profile across the device, enabling efficient cell capture by affinity at high flow rates. The recovery from whole blood is validated with cancer cell lines H1650 and MCF7, achieving a mean efficiency >80% at a throughput of 10 mL h(-1) in contrast to a flow rate of 1 mL h(-1) standardly reported with other microfluidic devices. Cells are recovered with a viability rate of 93% at these high speeds, increasing the ability to use captured CTCs for downstream analysis. Broad clinical application is demonstrated using comparable flow rates from blood specimens obtained from breast, pancreatic, and lung cancer patients. Comparable CTC numbers are recovered in all the samples at the two flow rates, demonstrating the ability of the technology to perform at high throughputs. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Optimization Design of Bipolar Plate Flow Field in PEM Stack

NASA Astrophysics Data System (ADS)

Wen, Ming; He, Kanghao; Li, Peilong; Yang, Lei; Deng, Li; Jiang, Fei; Yao, Yong

2017-12-01

A new design of bipolar plate flow field in proton exchange membrane (PEM) stack was presented to develop a high-performance transfer efficiency of the two-phase flow. Two different flow fields were studied by using numerical simulations and the performance of the flow fields was presented. the hydrodynamic properties include pressure gap between inlet and outlet, the Reynold’s number of the two types were compared based on the Navier-Stokes equations. Computer aided optimization software was implemented in the design of experiments of the preferable flow field. The design of experiments (DOE) for the favorable concept was carried out to study the hydrodynamic properties when changing the design parameters of the bipolar plate.

Comparison of intersecting pedestrian flows based on experiments

NASA Astrophysics Data System (ADS)

Zhang, J.; Seyfried, A.

2014-07-01

Intersections of pedestrian flows feature multiple types, varying in the numbers of flow directions as well as intersecting angles. In this article results from intersecting flow experiments with two different intersecting angles are compared. To analyze the transport capabilities the Voronoi method is used to resolve the fine structure of the resulting velocity-density relations and spatial dependence of the measurements. The fundamental diagrams of various flow types are compared and show no apparent difference with respect to the intersecting angle 90° and 180°. This result indicates that head-on conflicts of different types of flow have the same influence on the transport properties of the system, which demonstrates the high self-organization capabilities of pedestrians.

Bed-material entrainment and associated transportation infrastructure problems in streams of the Edwards Plateau, central Texas

USGS Publications Warehouse

Heitmuller, Franklin T.; Asquith, William H.

2008-01-01

The Texas Department of Transportation commonly builds and maintains low-water crossings (LWCs) over streams in the Edwards Plateau in Central Texas. LWCs are low-height structures, typically constructed of concrete and asphalt, that provide acceptable passage over seasonal rivers or streams with relatively low normal-depth flow. They are designed to accommodate flow by roadway overtopping during high-flow events. The streams of the Edwards Plateau are characterized by cobble- and gravel-sized bed material and highly variable flow regimes. Low base flows that occur most of the time occasionally are interrupted by severe floods. The floods entrain and transport substantial loads of bed material in the stream channels. As a result, LWCs over streams in the Edwards Plateau are bombarded and abraded by bed material during floods and periodically must be maintained or even replaced.

Sulfur volcanoes on Io?

NASA Astrophysics Data System (ADS)

Greeley, R.; Fink, J.

1985-04-01

The unusual rheological properties of molten sulfur, in which viscosity decreases approximately four orders of magnitude as it cools from 170 to 120 C, may result in distinctive volcanic flow morphologies that allow sulfur flows and volcanoes to be identified on Io. Search of high resolution Voyager images reveals three features--Atar Patera, Daedalus Patera, and Kibero Patera--considered to be possible sulfur volcanoes based on their morphology. All three average 250 km in diameter and are distinguished by circular-to-oval central masses surrounded by irregular, widespread flows. Geometric relations indicate that the flows were emplaced after the central zone and appear to have emanated from their margins. The central zones are interpreted to be domes representing the high temperature stage of sulfur formed initially upon eruption. Rapid quenching formed a crust which preserved this phase of the emplacement. Upon cooling to 170 C, the sulfur reached a low viscosity runny stage and was released as the thin, widespread flows.

Sulfur Volcanoes on Io?

NASA Technical Reports Server (NTRS)

Greeley, R.; Fink, J.

1985-01-01

The unusual rheological properties of molten sulfur, in which viscosity decreases approximately four orders of magnitude as it cools from 170 to 120 C, may result in distinctive volcanic flow morphologies that allow sulfur flows and volcanoes to be identified on Io. Search of high resolution Voyager images reveals three features--Atar Patera, Daedalus Patera, and Kibero Patera--considered to be possible sulfur volcanoes based on their morphology. All three average 250 km in diameter and are distinguished by circular-to-oval central masses surrounded by irregular, widespread flows. Geometric relations indicate that the flows were emplaced after the central zone and appear to have emanated from their margins. The central zones are interpreted to be domes representing the high temperature stage of sulfur formed initially upon eruption. Rapid quenching formed a crust which preserved this phase of the emplacement. Upon cooling to 170 C, the sulfur reached a low viscosity runny stage and was released as the thin, widespread flows.

Statistical parameters of thermally driven turbulent anabatic flow

NASA Astrophysics Data System (ADS)

Hilel, Roni; Liberzon, Dan

2016-11-01

Field measurements of thermally driven turbulent anabatic flow over a moderate slope are reported. A collocated hot-films-sonic anemometer (Combo) obtained the finer scales of the flow by implementing a Neural Networks based in-situ calibration technique. Eight days of continuous measurements of the wind and temperature fluctuations reviled a diurnal pattern of unstable stratification that forced development of highly turbulent unidirectional up slope flow. Empirical fits of important turbulence statistics were obtained from velocity fluctuations' time series alongside fully resolved spectra of velocity field components and characteristic length scales. TKE and TI showed linear dependence on Re, while velocity derivative skewness and dissipation rates indicated the anisotropic nature of the flow. Empirical fits of normalized velocity fluctuations power density spectra were derived as spectral shapes exhibited high level of similarity. Bursting phenomenon was detected at 15% of the total time. Frequency of occurrence, spectral characteristics and possible generation mechanism are discussed. BSF Grant #2014075.

Corner flow control in high through-flow axial commercial fan/booster using blade 3-D optimization

NASA Astrophysics Data System (ADS)

Zhu, Fang; Jin, Donghai; Gui, Xingmin

2012-02-01

This study is aimed at using blade 3-D optimization to control corner flows in the high through-flow fan/booster of a high bypass ratio commercial turbofan engine. Two kinds of blade 3-D optimization, end-bending and bow, are focused on. On account of the respective operation mode and environment, the approach to 3-D aerodynamic modeling of rotor blades is different from stator vanes. Based on the understanding of the mechanism of the corner flow and the consideration of intensity problem for rotors, this paper uses a variety of blade 3-D optimization approaches, such as loading distribution optimization, perturbation of departure angles and stacking-axis manipulation, which are suitable for rotors and stators respectively. The obtained 3-D blades and vanes can improve the corner flow features by end-bending and bow effects. The results of this study show that flows in corners of the fan/booster, such as the fan hub region, the tip and hub of the vanes of the booster, are very complex and dominated by 3-D effects. The secondary flows there are found to have a strong detrimental effect on the compressor performance. The effects of both end-bending and bow can improve the flow separation in corners, but the specific ways they work and application scope are somewhat different. Redesigning the blades via blade 3-D optimization to control the corner flow has effectively reduced the loss generation and improved the stall margin by a large amount.

High-lift flow-physics flight experiments on a subsonic civil transport aircraft (B737-100)

NASA Technical Reports Server (NTRS)

Vandam, Cornelis P.

1994-01-01

As part of the subsonic transport high-lift program, flight experiments are being conducted using NASA Langley's B737-100 to measure the flow characteristics of the multi-element high-lift system at full-scale high-Reynolds-number conditions. The instrumentation consists of hot-film anemometers to measure boundary-layer states, an infra-red camera to detect transition from laminar to turbulent flow, Preston tubes to measure wall shear stress, boundary-layer rakes to measure off-surface velocity profiles, and pressure orifices to measure surface pressure distributions. The initial phase of this research project was recently concluded with two flights on July 14. This phase consisted of a total of twenty flights over a period of about ten weeks. In the coming months the data obtained in this initial set of flight experiments will be analyzed and the results will be used to finalize the instrumentation layout for the next set of flight experiments scheduled for Winter and Spring of 1995. The main goal of these upcoming flights will be: (1) to measure more detailed surface pressure distributions across the wing for a range of flight conditions and flap settings; (2) to visualize the surface flows across the multi-element wing at high-lift conditions using fluorescent mini tufts; and (3) to measure in more detail the changes in boundary-layer state on the various flap elements as a result of changes in flight condition and flap deflection. These flight measured results are being correlated with experimental data measured in ground-based facilities as well as with computational data calculated with methods based on the Navier-Stokes equations or a reduced set of these equations. Also these results provide insight into the extent of laminar flow that exists on actual multi-element lifting surfaces at full-scale high-life conditions. Preliminary results indicate that depending on the deflection angle, the slat and flap elements have significant regions of laminar flow over a wide range of angles of attack. Boundary-layer transition mechanisms that were observed include attachment-line contamination on the slat and inflectional instability on the slat and fore flap. Also, the results agree fairly well with the predictions reported in a paper presented at last year's AIAA Fluid Dynamics Conference. The fact that extended regions of laminar flow are shown to exist on the various elements of the high-lift system raises the question what the effect is of loss of laminar flow as a result of insect contamiantion, rain or ice accumulation on high-life performance.

Modification of the Douglas Neumann program to improve the efficiency of predicting component interference and high lift characteristics

NASA Technical Reports Server (NTRS)

Bristow, D. R.; Grose, G. G.

1978-01-01

The Douglas Neumann method for low-speed potential flow on arbitrary three-dimensional lifting bodies was modified by substituting the combined source and doublet surface paneling based on Green's identity for the original source panels. Numerical studies show improved accuracy and stability for thin lifting surfaces, permitting reduced panel number for high-lift devices and supercritical airfoil sections. The accuracy of flow in concave corners is improved. A method of airfoil section design for a given pressure distribution, based on Green's identity, was demonstrated. The program uses panels on the body surface with constant source strength and parabolic distribution of doublet strength, and a doublet sheet on the wake. The program is written for the CDC CYBER 175 computer. Results of calculations are presented for isolated bodies, wings, wing-body combinations, and internal flow.

FISH-Flow, a protocol for the concurrent detection of mRNA and protein in single cells using fluorescence in situ hybridization and flow cytometry

PubMed Central

Arrigucci, Riccardo; Bushkin, Yuri; Radford, Felix; Lakehal, Karim; Vir, Pooja; Pine, Richard; Martin, December; Sugarman, Jeffrey; Zhao, Yanlin; Yap, George S; Lardizabal, Alfred A; Tyagi, Sanjay; Gennaro, Maria Laura

2017-01-01

We describe a flow-cytometry-based protocol for intracellular mRNA measurements in nonadherent mammalian cells using fluorescence in situ hybridization (FISH) probes. The method, which we call FISH-Flow, allows for high-throughput multiparametric measurements of gene expression, a task that was not feasible with earlier, microscopy-based approaches. The FISH-Flow protocol involves cell fixation, permeabilization and hybridization with a set of fluorescently labeled oligonucleotide probes. In this protocol, surface and intracellular protein markers can also be stained with fluorescently labeled antibodies for simultaneous protein and mRNA measurement. Moreover, a semiautomated, single-tube version of the protocol can be performed with a commercially available cell-wash device that reduces cell loss, operator time and interoperator variability. It takes ~30 h to perform this protocol. An example of FISH-Flow measurements of cytokine mRNA induction by ex vivo stimulation of primed T cells with specific antigens is described. PMID:28518171

Adjoint Sensitivity Analysis for Scale-Resolving Turbulent Flow Solvers

NASA Astrophysics Data System (ADS)

Blonigan, Patrick; Garai, Anirban; Diosady, Laslo; Murman, Scott

2017-11-01

Adjoint-based sensitivity analysis methods are powerful design tools for engineers who use computational fluid dynamics. In recent years, these engineers have started to use scale-resolving simulations like large-eddy simulations (LES) and direct numerical simulations (DNS), which resolve more scales in complex flows with unsteady separation and jets than the widely-used Reynolds-averaged Navier-Stokes (RANS) methods. However, the conventional adjoint method computes large, unusable sensitivities for scale-resolving simulations, which unlike RANS simulations exhibit the chaotic dynamics inherent in turbulent flows. Sensitivity analysis based on least-squares shadowing (LSS) avoids the issues encountered by conventional adjoint methods, but has a high computational cost even for relatively small simulations. The following talk discusses a more computationally efficient formulation of LSS, ``non-intrusive'' LSS, and its application to turbulent flows simulated with a discontinuous-Galkerin spectral-element-method LES/DNS solver. Results are presented for the minimal flow unit, a turbulent channel flow with a limited streamwise and spanwise domain.

Fast blood flow monitoring in deep tissues with real-time software correlators

PubMed Central

Wang, Detian; Parthasarathy, Ashwin B.; Baker, Wesley B.; Gannon, Kimberly; Kavuri, Venki; Ko, Tiffany; Schenkel, Steven; Li, Zhe; Li, Zeren; Mullen, Michael T.; Detre, John A.; Yodh, Arjun G.

2016-01-01

We introduce, validate and demonstrate a new software correlator for high-speed measurement of blood flow in deep tissues based on diffuse correlation spectroscopy (DCS). The software correlator scheme employs standard PC-based data acquisition boards to measure temporal intensity autocorrelation functions continuously at 50 – 100 Hz, the fastest blood flow measurements reported with DCS to date. The data streams, obtained in vivo for typical source-detector separations of 2.5 cm, easily resolve pulsatile heart-beat fluctuations in blood flow which were previously considered to be noise. We employ the device to separate tissue blood flow from tissue absorption/scattering dynamics and thereby show that the origin of the pulsatile DCS signal is primarily flow, and we monitor cerebral autoregulation dynamics in healthy volunteers more accurately than with traditional instrumentation as a result of increased data acquisition rates. Finally, we characterize measurement signal-to-noise ratio and identify count rate and averaging parameters needed for optimal performance. PMID:27231588

Performance of high flow rate samplers for respirable particle collection.

PubMed

Lee, Taekhee; Kim, Seung Won; Chisholm, William P; Slaven, James; Harper, Martin

2010-08-01

The American Conference of Governmental Industrial hygienists (ACGIH) lowered the threshold limit value (TLV) for respirable crystalline silica (RCS) exposure from 0.05 to 0.025 mg m(-3) in 2006. For a working environment with an airborne dust concentration near this lowered TLV, the sample collected with current standard respirable aerosol samplers might not provide enough RCS for quantitative analysis. Adopting high flow rate sampling devices for respirable dust containing silica may provide a sufficient amount of RCS to be above the limit of quantification even for samples collected for less than full shift. The performances of three high flow rate respirable samplers (CIP10-R, GK2.69, and FSP10) have been evaluated in this study. Eleven different sizes of monodisperse aerosols of ammonium fluorescein were generated with a vibrating orifice aerosol generator in a calm air chamber in order to determine the sampling efficiency of each sampler. Aluminum oxide particles generated by a fluidized bed aerosol generator were used to test (i) the uniformity of a modified calm air chamber, (ii) the effect of loading on the sampling efficiency, and (iii) the performance of dust collection compared to lower flow rate cyclones in common use in the USA (10-mm nylon and Higgins-Dewell cyclones). The coefficient of variation for eight simultaneous samples in the modified calm air chamber ranged from 1.9 to 6.1% for triplicate measures of three different aerosols. The 50% cutoff size ((50)d(ae)) of the high flow rate samplers operated at the flow rates recommended by manufacturers were determined as 4.7, 4.1, and 4.8 microm for CIP10-R, GK2.69, and FSP10, respectively. The mass concentration ratio of the high flow rate samplers to the low flow rate cyclones decreased with decreasing mass median aerodynamic diameter (MMAD) and high flow rate samplers collected more dust than low flow rate samplers by a range of 2-11 times based on gravimetric analysis. Dust loading inside the high flow rate samplers does not appear to affect the particle separation in either FSP10 or GK2.69. The high flow rate samplers overestimated compared to the International Standards Organization/Comité Européen de Normalisation/ACGIH respirable convention [up to 40% at large MMAD (27.5 microm)] and could provide overestimated exposure data with the current flow rates. However, both cyclones appeared to be able to provide relatively unbiased assessments of RCS when their flow rates were adjusted.

Performance of High Flow Rate Samplers for Respirable Particle Collection

PubMed Central

Lee, Taekhee; Kim, Seung Won; Chisholm, William P.; Slaven, James; Harper, Martin

2010-01-01

The American Conference of Governmental Industrial hygienists (ACGIH) lowered the threshold limit value (TLV) for respirable crystalline silica (RCS) exposure from 0.05 to 0.025 mg m−3 in 2006. For a working environment with an airborne dust concentration near this lowered TLV, the sample collected with current standard respirable aerosol samplers might not provide enough RCS for quantitative analysis. Adopting high flow rate sampling devices for respirable dust containing silica may provide a sufficient amount of RCS to be above the limit of quantification even for samples collected for less than full shift. The performances of three high flow rate respirable samplers (CIP10-R, GK2.69, and FSP10) have been evaluated in this study. Eleven different sizes of monodisperse aerosols of ammonium fluorescein were generated with a vibrating orifice aerosol generator in a calm air chamber in order to determine the sampling efficiency of each sampler. Aluminum oxide particles generated by a fluidized bed aerosol generator were used to test (i) the uniformity of a modified calm air chamber, (ii) the effect of loading on the sampling efficiency, and (iii) the performance of dust collection compared to lower flow rate cyclones in common use in the USA (10-mm nylon and Higgins–Dewell cyclones). The coefficient of variation for eight simultaneous samples in the modified calm air chamber ranged from 1.9 to 6.1% for triplicate measures of three different aerosols. The 50% cutoff size (50dae) of the high flow rate samplers operated at the flow rates recommended by manufacturers were determined as 4.7, 4.1, and 4.8 μm for CIP10-R, GK2.69, and FSP10, respectively. The mass concentration ratio of the high flow rate samplers to the low flow rate cyclones decreased with decreasing mass median aerodynamic diameter (MMAD) and high flow rate samplers collected more dust than low flow rate samplers by a range of 2–11 times based on gravimetric analysis. Dust loading inside the high flow rate samplers does not appear to affect the particle separation in either FSP10 or GK2.69. The high flow rate samplers overestimated compared to the International Standards Organization/Comité Européen de Normalisation/ACGIH respirable convention [up to 40% at large MMAD (27.5 μm)] and could provide overestimated exposure data with the current flow rates. However, both cyclones appeared to be able to provide relatively unbiased assessments of RCS when their flow rates were adjusted. PMID:20660144

A new method to calculate unsteady particle kinematics and drag coefficient in a subsonic post-shock flow

NASA Astrophysics Data System (ADS)

Bordoloi, Ankur D.; Ding, Liuyang; Martinez, Adam A.; Prestridge, Katherine; Adrian, Ronald J.

2018-07-01

We introduce a new method (piecewise integrated dynamics equation fit, PIDEF) that uses the particle dynamics equation to determine unsteady kinematics and drag coefficient (C D) for a particle in subsonic post-shock flow. The uncertainty of this method is assessed based on simulated trajectories for both quasi-steady and unsteady flow conditions. Traditional piecewise polynomial fitting (PPF) shows high sensitivity to measurement error and the function used to describe C D, creating high levels of relative error (1) when applied to unsteady shock-accelerated flows. The PIDEF method provides reduced uncertainty in calculations of unsteady acceleration and drag coefficient for both quasi-steady and unsteady flows. This makes PIDEF a preferable method over PPF for complex flows where the temporal response of C D is unknown. We apply PIDEF to experimental measurements of particle trajectories from 8-pulse particle tracking and determine the effect of incident Mach number on relaxation kinematics and drag coefficient of micron-sized particles.

Automated flow cytometric analysis across large numbers of samples and cell types.

PubMed

Chen, Xiaoyi; Hasan, Milena; Libri, Valentina; Urrutia, Alejandra; Beitz, Benoît; Rouilly, Vincent; Duffy, Darragh; Patin, Étienne; Chalmond, Bernard; Rogge, Lars; Quintana-Murci, Lluis; Albert, Matthew L; Schwikowski, Benno

2015-04-01

Multi-parametric flow cytometry is a key technology for characterization of immune cell phenotypes. However, robust high-dimensional post-analytic strategies for automated data analysis in large numbers of donors are still lacking. Here, we report a computational pipeline, called FlowGM, which minimizes operator input, is insensitive to compensation settings, and can be adapted to different analytic panels. A Gaussian Mixture Model (GMM)-based approach was utilized for initial clustering, with the number of clusters determined using Bayesian Information Criterion. Meta-clustering in a reference donor permitted automated identification of 24 cell types across four panels. Cluster labels were integrated into FCS files, thus permitting comparisons to manual gating. Cell numbers and coefficient of variation (CV) were similar between FlowGM and conventional gating for lymphocyte populations, but notably FlowGM provided improved discrimination of "hard-to-gate" monocyte and dendritic cell (DC) subsets. FlowGM thus provides rapid high-dimensional analysis of cell phenotypes and is amenable to cohort studies. Copyright © 2015. Published by Elsevier Inc.

Plastic deformation treated as material flow through adjustable crystal lattice

NASA Astrophysics Data System (ADS)

Minakowski, P.; Hron, J.; Kratochvíl, J.; Kružík, M.; Málek, J.

2014-08-01

Looking at severe plastic deformation experiments, it seems that crystalline materials at yield behave as a special kind of anisotropic, highly viscous fluids flowing through an adjustable crystal lattice space. High viscosity provides a possibility to describe the flow as a quasi-static process, where inertial and other body forces can be neglected. The flow through the lattice space is restricted to preferred crystallographic planes and directions causing anisotropy. In the deformation process the lattice is strained and rotated. The proposed model is based on the rate form of the decomposition rule: the velocity gradient consists of the lattice velocity gradient and the sum of the velocity gradients corresponding to the slip rates of individual slip systems. The proposed crystal plasticity model allowing for large deformations is treated as the flow-adjusted boundary value problem. As a test example we analyze a plastic flow of an single crystal compressed in a channel die. We propose three step algorithm of finite element discretization for a numerical solution in the Arbitrary Lagrangian Eulerian (ALE) configuration.

Testing Small CPAS Parachutes Using HIVAS

NASA Technical Reports Server (NTRS)

Ray, Eric S.; Hennings, Elsa; Bernatovich, Michael A.

2013-01-01

The High Velocity Airflow System (HIVAS) facility at the Naval Air Warfare Center (NAWC) at China Lake was successfully used as an alternative to flight test to determine parachute drag performance of two small Capsule Parachute Assembly System (CPAS) canopies. A similar parachute with known performance was also tested as a control. Realtime computations of drag coefficient were unrealistically low. This is because HIVAS produces a non-uniform flow which rapidly decays from a high central core flow. Additional calibration runs were performed to characterize this flow assuming radial symmetry from the centerline. The flow field was used to post-process effective flow velocities at each throttle setting and parachute diameter using the definition of the momentum flux factor. Because one parachute had significant oscillations, additional calculations were required to estimate the projected flow at off-axis angles. The resulting drag data from HIVAS compared favorably to previously estimated parachute performance based on scaled data from analogous CPAS parachutes. The data will improve drag area distributions in the next version of the CPAS Model Memo.

Contrasting dissolved organic carbon dynamics at two forested catchments interpreted from high-frequency optical sensor measurements

NASA Astrophysics Data System (ADS)

Saraceno, J.; Shanley, J. B.

2015-12-01

Stream dissolved organic carbon (DOC) concentrations can change rapidly during high-flow events. The timing and magnitude of these changes relative to the event hydrograph can yield insights about possible DOC sources its flow paths to the stream. In situ fluorescent dissolved organic matter (FDOM) sensors that generate high-frequency observations enable detailed examination of high-flow DOC- discharge hysteresis. In this presentation, we interpret high-flow DOC dynamics at two of the five U.S. Geological Survey (USGS) Water, Energy, and Biogeochemical Budgets (WEBB) sites - Panola Mountain, Georgia and Sleepers River, Vermont. Based on laboratory analyses of weekly and event grab samples, both USGS WEBB sites had a similar DOC ranges: from ~1 milligrams per liter (mg/L) at base flow to ~11-15 mg/L during the largest events. A curvilinear relationship between DOC and FDOM (corrected for temperature and turbidity interferences) was used to model a continuous time series of DOC. At the Sleepers River site, DOC showed a seasonal pattern of increasing DOC response; from fairly subdued during spring snowmelt, to a maximum during autumn leaf-fall. The DOC response to discharge showed a consistent clockwise hysteresis (DOC peak, lagged discharge peak). At the Panola Mountain site, maximum event DOC response was lower during wet conditions in the winter and spring. Hysteresis was less expressed at Panola Mountain relative to Sleepers River and displayed both clockwise and counterclockwise patterns, which were dependent on antecedent moisture conditions. The greater synchrony of DOC and discharge peaks at Panola Mountain suggests that DOC sources are closer to the stream and (or) move to the stream more quickly, than at Sleepers River.

Development of a novel parallel-spool pilot operated high-pressure solenoid valve with high flow rate and high speed

NASA Astrophysics Data System (ADS)

Dong, Dai; Li, Xiaoning

2015-03-01

High-pressure solenoid valve with high flow rate and high speed is a key component in an underwater driving system. However, traditional single spool pilot operated valve cannot meet the demands of both high flow rate and high speed simultaneously. A new structure for a high pressure solenoid valve is needed to meet the demand of the underwater driving system. A novel parallel-spool pilot operated high-pressure solenoid valve is proposed to overcome the drawback of the current single spool design. Mathematical models of the opening process and flow rate of the valve are established. Opening response time of the valve is subdivided into 4 parts to analyze the properties of the opening response. Corresponding formulas to solve 4 parts of the response time are derived. Key factors that influence the opening response time are analyzed. According to the mathematical model of the valve, a simulation of the opening process is carried out by MATLAB. Parameters are chosen based on theoretical analysis to design the test prototype of the new type of valve. Opening response time of the designed valve is tested by verifying response of the current in the coil and displacement of the main valve spool. The experimental results are in agreement with the simulated results, therefore the validity of the theoretical analysis is verified. Experimental opening response time of the valve is 48.3 ms at working pressure of 10 MPa. The flow capacity test shows that the largest effective area is 126 mm2 and the largest air flow rate is 2320 L/s. According to the result of the load driving test, the valve can meet the demands of the driving system. The proposed valve with parallel spools provides a new method for the design of a high-pressure valve with fast response and large flow rate.

Properties of the Mean Momentum Balance in Polymer Drag Reduced Channel Flow

NASA Astrophysics Data System (ADS)

White, Christopher; Dubief, Yves; Klewicki, Joseph

2014-11-01

The redistribution of mean momentum and the underlying mechanisms of the redistribution process in polymer drag reduced channel flow are investigated by employing a mean momentum equation based analysis. The work is motivated by recent studies that showed (contrary to long-held views) that polymers modify the von Karman coefficient, κ, at low drag reduction, and at some relatively high drag reduction eradicate the inertially dominated logarithmic region. Since κ is a manifestation of the underlying dynamical behaviors of wall-bounded flow, understanding how polymers modify κ is inherently important to understanding the dynamics of polymer drag reduced flow, and, consequently, the phenomenon of polymer drag reduction. The goal of the present study is to explore and quantify these effects within the framework of a mean momentum based analysis.

High resolution solutions of the Euler equations for vortex flows

NASA Technical Reports Server (NTRS)

Murman, E. M.; Powell, K. G.; Rizzi, A.

1985-01-01

Solutions of the Euler equations are presented for M = 1.5 flow past a 70-degree-swept delta wing. At an angle of attack of 10 degrees, strong leading-edge vortices are produced. Two computational approaches are taken, based upon fully three-dimensional and conical flow theory. Both methods utilize a finite-volume discretization solved by a pseudounsteady multistage scheme. Results from the two approaches are in good agreement. Computations have been done on a 16-million-word CYBER 205 using 196 x 56 x 96 and 128 x 128 cells for the two methods. A sizable data base is generated, and some of the practical aspects of manipulating it are mentioned. The results reveal many interesting physical features of the compressible vortical flow field and also suggest new areas needing research.

Dynamic autonomous routing technology for IP-based satellite ad hoc networks

NASA Astrophysics Data System (ADS)

Wang, Xiaofei; Deng, Jing; Kostas, Theresa; Rajappan, Gowri

2014-06-01

IP-based routing for military LEO/MEO satellite ad hoc networks is very challenging due to network and traffic heterogeneity, network topology and traffic dynamics. In this paper, we describe a traffic priority-aware routing scheme for such networks, namely Dynamic Autonomous Routing Technology (DART) for satellite ad hoc networks. DART has a cross-layer design, and conducts routing and resource reservation concurrently for optimal performance in the fluid but predictable satellite ad hoc networks. DART ensures end-to-end data delivery with QoS assurances by only choosing routing paths that have sufficient resources, supporting different packet priority levels. In order to do so, DART incorporates several resource management and innovative routing mechanisms, which dynamically adapt to best fit the prevailing conditions. In particular, DART integrates a resource reservation mechanism to reserve network bandwidth resources; a proactive routing mechanism to set up non-overlapping spanning trees to segregate high priority traffic flows from lower priority flows so that the high priority flows do not face contention from low priority flows; a reactive routing mechanism to arbitrate resources between various traffic priorities when needed; a predictive routing mechanism to set up routes for scheduled missions and for anticipated topology changes for QoS assurance. We present simulation results showing the performance of DART. We have conducted these simulations using the Iridium constellation and trajectories as well as realistic military communications scenarios. The simulation results demonstrate DART's ability to discriminate between high-priority and low-priority traffic flows and ensure disparate QoS requirements of these traffic flows.

Through-Flow Calculations in Axial Turbomachinery

DTIC Science & Technology

1976-10-01

coilditions should be next on the agenda. Authors’ response: I think the process is essentially iterative between SI and S2 solutions. If SI surfaces...secondary flows in high Mach number situations. Concerning Gelder’s approach, i think that your remark is rather optimistic. We use a method based on...my remarks on Gelder’s work were based on calculations made by Gelder himself. One or two other people have managed to get the calculation through

Effective star tracking method based on optical flow analysis for star trackers.

PubMed

Sun, Ting; Xing, Fei; Wang, Xiaochu; Li, Jin; Wei, Minsong; You, Zheng

2016-12-20

Benefiting from rapid development of imaging sensor technology, modern optical technology, and a high-speed computing chip, the star tracker's accuracy, dynamic performance, and update rate have been greatly improved with low power consumption and miniature size. The star tracker is currently one of the most competitive attitude measurement sensors. However, due to restrictions of the optical imaging system, difficulties still exist in moving star spot detection and star tracking when in special motion conditions. An effective star tracking method based on optical flow analysis for star trackers is proposed in this paper. Spot-based optical flow, based on a gray gradient between two adjacent star images, is analyzed to distinguish the star spot region and obtain an accurate star spot position so that the star tracking can keep continuous under high dynamic conditions. The obtained star vectors and extended Kalman filter (EKF) are then combined to conduct an angular velocity estimation to ensure region prediction of the star spot; this can be combined with the optical flow analysis result. Experiment results show that the method proposed in this paper has advantages in conditions of large angular velocity and large angular acceleration, despite the presence of noise. Higher functional density and better performance can be achieved; thus, the star tracker can be more widely applied in small satellites, remote sensing, and other complex space missions.

Dataflow computing approach in high-speed digital simulation

NASA Technical Reports Server (NTRS)

Ercegovac, M. D.; Karplus, W. J.

1984-01-01

New computational tools and methodologies for the digital simulation of continuous systems were explored. Programmability, and cost effective performance in multiprocessor organizations for real time simulation was investigated. Approach is based on functional style languages and data flow computing principles, which allow for the natural representation of parallelism in algorithms and provides a suitable basis for the design of cost effective high performance distributed systems. The objectives of this research are to: (1) perform comparative evaluation of several existing data flow languages and develop an experimental data flow language suitable for real time simulation using multiprocessor systems; (2) investigate the main issues that arise in the architecture and organization of data flow multiprocessors for real time simulation; and (3) develop and apply performance evaluation models in typical applications.

High-Fidelity Thermal Radiation Models and Measurements for High-Pressure Reacting Laminar and Turbulent Flows

DTIC Science & Technology

2013-06-26

flow code used ( OpenFOAM ) to include differential diffusion and cell-based stochastic RTE solvers. The models were validated by simulation of laminar...wavenumber selection is improved about by a factor of 10. (5) OpenFOAM Improvements for Laminar Flames A laminar-diffusion combustion solver, taking into...account the effects of differential diffusion, was developed within the open source CFD package OpenFOAM [18]. In addition, OpenFOAM was augmented to take

Tendon exhibits complex poroelastic behavior at the nanoscale as revealed by high-frequency AFM-based rheology.

PubMed

Connizzo, Brianne K; Grodzinsky, Alan J

2017-03-21

Tendons transmit load from muscle to bone by utilizing their unique static and viscoelastic tensile properties. These properties are highly dependent on the composition and structure of the tissue matrix, including the collagen I hierarchy, proteoglycans, and water. While the role of matrix constituents in the tensile response has been studied, their role in compression, particularly in matrix pressurization via regulation of fluid flow, is not well understood. Injured or diseased tendons and tendon regions that naturally experience compression are known to have alterations in glycosaminoglycan content, which could modulate fluid flow and ultimately mechanical function. While recent theoretical studies have predicted tendon mechanics using poroelastic theory, no experimental data have directly demonstrated such behavior. In this study, we use high-bandwidth AFM-based rheology to determine the dynamic response of tendons to compressive loading at the nanoscale and to determine the presence of poroelastic behavior. Tendons are found to have significant characteristic dynamic relaxation behavior occurring at both low and high frequencies. Classic poroelastic behavior is observed, although we hypothesize that the full dynamic response is caused by a combination of flow-dependent poroelasticity as well as flow-independent viscoelasticity. Tendons also demonstrate regional dependence in their dynamic response, particularly near the junction of tendon and bone, suggesting that the structural and compositional heterogeneity in tendon may be responsible for regional poroelastic behavior. Overall, these experiments provide the foundation for understanding fluid-flow-dependent poroelastic mechanics of tendon, and the methodology is valuable for assessing changes in tendon matrix compressive behavior at the nanoscale. Copyright © 2017 Elsevier Ltd. All rights reserved.

Effects of Experimental High Flow Releases and Increased Fluctuations in Flow from Glen Canyon Dam on Abundance, Growth, and Survival Rates of Early Life Stages of Rainbow Trout in the Lee's Ferry Reach of the Colorado River

NASA Astrophysics Data System (ADS)

Korman, Josh

2010-05-01

The abundance of adult fish populations is controlled by the growth and survival rates of early life stages. Evaluating the effects of flow regimes on early life stages is therefore critical to determine how these regimes affect the abundance of adult populations. Experimental high flow releases from Glen Canyon Dam, primarily intended to conserve fine sediment and improve habitat conditions for native fish in the Colorado River in Grand Canyon, AZ, have been conducted in 1996, 2004, and 2008. These flows potentially affect the Lee's Ferry reach rainbow trout population, located immediately downstream of the dam, which supports a highly valued fishery and likely influences the abundance of rainbow trout in Grand Canyon. Due to concerns about negative effects of high trout abundance on endangered native fish, hourly variation in flow from Glen Canyon Dam was experimentally increased between 2003 and 2005 to reduce trout abundance. This study reports on the effects of experimental high flow releases and fluctuating flows on early life stages of rainbow trout in the Lee's Ferry reach based on monthly sampling of redds (egg nests) and the abundance and growth of age-0 trout between 2003 and 2009. Data on spawn timing, spawning elevations, and intergravel temperatures were integrated in a model to estimate the magnitude and seasonal trend in incubation mortality resulting from redd dewatering due to fluctuations in flow. Experimental fluctuations from January through March promoted spawning at higher elevations where the duration of dewatering was longer and intergravel temperatures exceeded lethal thresholds. Flow-dependent incubation mortality rates were 24% (2003) and 50% (2004) in years with higher flow fluctuations, compared to 5-11% under normal operations (2006-2009). Spatial and temporal predictions of mortality were consistent with direct observations of egg mortality determined from the excavation of 125 redds. The amount of variation in backcalculated hatch date distributions predicted by flow-independent (84-93%) and flow-dependent (82-91%) incubation loss models were similar. Age-0 abundance was generally independent of viable egg deposition, except in one year when egg deposition was 10-fold lower due to reduced spawning activity. There was no evidence from the hatch date or stock-recruitment analysis that flow-dependent incubation losses, although large in experimental years, affected the abundance of the age-0 population. The data indicate that strong compensation in survival rates shortly after emergence mitigated the impact of flow-dependent losses. Multiple lines of evidence demonstrated that the March 2008 high flow experiment (HFE) resulted in a large increase in early survival rates (fertilization to ~1-2 months from emergence) of age-0 trout due an improvement in habitat conditions. A stock-recruitment analysis indicated that age-0 abundance in July 2008 was over four-fold higher than expected given the number of viable redds that produced these fish. A hatch date analysis indicated that early survival rates were much higher for cohorts that emerged about two months after the HFE. These cohorts, which were fertilized after the HFE, were not exposed to high flows and emerged into better quality habitat. Inter annual differences in growth of age-0 trout based on otolith microstructure support this hypothesis. Growth rates in the summer and fall of 2008 (0.44 mm·day-1) were virtually the same as in 2006 (0.46 mm·day-1), the highest recorded over six years, even though abundance was eight-fold greater in 2008. I speculate that high flows in 2008 increased interstitial spaces in the substrate and food availability or quality, leading to higher early survival of recently emerged trout and better growth during summer and fall. Abundance in 2009 was over two-fold higher than expected, possibly indicating that the effect of the HFE on early life stages was somewhat persistent.

Flow cytometry sorting of nuclei enables the first global characterization of Paramecium germline DNA and transposable elements.

PubMed

Guérin, Frédéric; Arnaiz, Olivier; Boggetto, Nicole; Denby Wilkes, Cyril; Meyer, Eric; Sperling, Linda; Duharcourt, Sandra

2017-04-26

DNA elimination is developmentally programmed in a wide variety of eukaryotes, including unicellular ciliates, and leads to the generation of distinct germline and somatic genomes. The ciliate Paramecium tetraurelia harbors two types of nuclei with different functions and genome structures. The transcriptionally inactive micronucleus contains the complete germline genome, while the somatic macronucleus contains a reduced genome streamlined for gene expression. During development of the somatic macronucleus, the germline genome undergoes massive and reproducible DNA elimination events. Availability of both the somatic and germline genomes is essential to examine the genome changes that occur during programmed DNA elimination and ultimately decipher the mechanisms underlying the specific removal of germline-limited sequences. We developed a novel experimental approach that uses flow cell imaging and flow cytometry to sort subpopulations of nuclei to high purity. We sorted vegetative micronuclei and macronuclei during development of P. tetraurelia. We validated the method by flow cell imaging and by high throughput DNA sequencing. Our work establishes the proof of principle that developing somatic macronuclei can be sorted from a complex biological sample to high purity based on their size, shape and DNA content. This method enabled us to sequence, for the first time, the germline DNA from pure micronuclei and to identify novel transposable elements. Sequencing the germline DNA confirms that the Pgm domesticated transposase is required for the excision of all ~45,000 Internal Eliminated Sequences. Comparison of the germline DNA and unrearranged DNA obtained from PGM-silenced cells reveals that the latter does not provide a faithful representation of the germline genome. We developed a flow cytometry-based method to purify P. tetraurelia nuclei to high purity and provided quality control with flow cell imaging and high throughput DNA sequencing. We identified 61 germline transposable elements including the first Paramecium retrotransposons. This approach paves the way to sequence the germline genomes of P. aurelia sibling species for future comparative genomic studies.

Ultrafast Microfluidic Cellular Imaging by Optical Time-Stretch.

PubMed

Lau, Andy K S; Wong, Terence T W; Shum, Ho Cheung; Wong, Kenneth K Y; Tsia, Kevin K

2016-01-01

There is an unmet need in biomedicine for measuring a multitude of parameters of individual cells (i.e., high content) in a large population efficiently (i.e., high throughput). This is particularly driven by the emerging interest in bringing Big-Data analysis into this arena, encompassing pathology, drug discovery, rare cancer cell detection, emulsion microdroplet assays, to name a few. This momentum is particularly evident in recent advancements in flow cytometry. They include scaling of the number of measurable colors from the labeled cells and incorporation of imaging capability to access the morphological information of the cells. However, an unspoken predicament appears in the current technologies: higher content comes at the expense of lower throughput, and vice versa. For example, accessing additional spatial information of individual cells, imaging flow cytometers only achieve an imaging throughput ~1000 cells/s, orders of magnitude slower than the non-imaging flow cytometers. In this chapter, we introduce an entirely new imaging platform, namely optical time-stretch microscopy, for ultrahigh speed and high contrast label-free single-cell (in a ultrafast microfluidic flow up to 10 m/s) imaging and analysis with an ultra-fast imaging line-scan rate as high as tens of MHz. Based on this technique, not only morphological information of the individual cells can be obtained in an ultrafast manner, quantitative evaluation of cellular information (e.g., cell volume, mass, refractive index, stiffness, membrane tension) at nanometer scale based on the optical phase is also possible. The technology can also be integrated with conventional fluorescence measurements widely adopted in the non-imaging flow cytometers. Therefore, these two combinatorial and complementary measurement capabilities in long run is an attractive platform for addressing the pressing need for expanding the "parameter space" in high-throughput single-cell analysis. This chapter provides the general guidelines of constructing the optical system for time stretch imaging, fabrication and design of the microfluidic chip for ultrafast fluidic flow, as well as the image acquisition and processing.

Least Median of Squares Filtering of Locally Optimal Point Matches for Compressible Flow Image Registration

PubMed Central

Castillo, Edward; Castillo, Richard; White, Benjamin; Rojo, Javier; Guerrero, Thomas

2012-01-01

Compressible flow based image registration operates under the assumption that the mass of the imaged material is conserved from one image to the next. Depending on how the mass conservation assumption is modeled, the performance of existing compressible flow methods is limited by factors such as image quality, noise, large magnitude voxel displacements, and computational requirements. The Least Median of Squares Filtered Compressible Flow (LFC) method introduced here is based on a localized, nonlinear least squares, compressible flow model that describes the displacement of a single voxel that lends itself to a simple grid search (block matching) optimization strategy. Spatially inaccurate grid search point matches, corresponding to erroneous local minimizers of the nonlinear compressible flow model, are removed by a novel filtering approach based on least median of squares fitting and the forward search outlier detection method. The spatial accuracy of the method is measured using ten thoracic CT image sets and large samples of expert determined landmarks (available at www.dir-lab.com). The LFC method produces an average error within the intra-observer error on eight of the ten cases, indicating that the method is capable of achieving a high spatial accuracy for thoracic CT registration. PMID:22797602

Flight-measured pressure characteristics of aft-facing steps in high Reynolds number flow at Mach numbers of 2.20, 2.50, and 2.80 and comparison with other data

NASA Technical Reports Server (NTRS)

Powers, S. G.

1978-01-01

The YF-12 airplane was studied to determine the pressure characteristics associated with an aft-facing step in high Reynolds number flow for nominal Mach numbers of 2.20, 2.50, and 2.80. Base pressure coefficients were obtained for three step heights. The surface static pressures ahead of and behind the step were measured for the no-step condition and for each of the step heights. A boundary layer rake was used to determine the local boundary layer conditions. The Reynolds number based on the length of flow ahead of the step was approximately 10 to the 8th power and the ratios of momentum thickness to step height ranged from 0.2 to 1.0. Base pressure coefficients were compared with other available data at similar Mach numbers and at ratios of momentum thickness to step height near 1.0. In addition, the data were compared with base pressure coefficients calculated by a semiempirical prediction method. The base pressure ratios are shown to be a function of Reynolds number based on momentum thickness. Profiles of the surface pressures ahead of and behind the step and the local boundary layer conditions are also presented.

Methylation of 2-Naphthol Using Dimethyl Carbonate under Continuous-Flow Gas-Phase Conditions

ERIC Educational Resources Information Center

Tundo, Pietro; Rosamilia, Anthony E.; Arico, Fabio

2010-01-01

This experiment investigates the methylation of 2-naphthol with dimethyl carbonate. The volatility of the substrates, products, and co-products allows the reaction to be performed using a continuous-flow gas-phase setup at ambient pressure. The reaction uses catalytic quantities of base, achieves high conversion, produces little waste, and…

Spectroscopy-based thrust sensor for high-speed gaseous flows

NASA Technical Reports Server (NTRS)

Hanson, Ronald K. (Inventor)

1993-01-01

A system and method for non-intrusively obtaining the thrust value of combustion by-products of a jet engine is disclosed herein. The system includes laser elements for inducing absorption for use in determining the axial velocity and density of the jet flow stream and elements for calculating the thrust value therefrom.

Prediction of E. coli release from streambed to water column during base flow periods using SWAT model

USDA-ARS?s Scientific Manuscript database

Microbial water quality in streams is of importance for recreation, irrigation, and other uses. The streambed sediment has been shown to harbor large fecal indicator bacteria (FIB) population that can be released to water column during high-flow events when sediments are resuspended. There have been...

Potential effects of elevated base flow and midsummer spike flow experiments on riparian vegetation along the Green River

USGS Publications Warehouse

Friedman, Jonathan M.

2018-01-01

needs of other riverine resources. Use of high flows to remove unwanted vegetation is constrained by current operational guidance for Flaming Gorge Dam, which attempts to limit spills (i.e., flows greater than 8600 ft3 /s) that might contribute to cavitation and lead to dam safety concerns. Therefore, reversing vegetation encroachment is more likely to succeed if implemented while plants are still small. Annual monitoring of near-channel vegetation and topography would enable managers to prescribe a timely hydrologic response in case the proposed flow experiments lead to vegetation encroachment and habitat degradation.

Modelling the Transport of Nanoparticles under Blood Flow using an Agent-based Approach.

PubMed

Fullstone, Gavin; Wood, Jonathan; Holcombe, Mike; Battaglia, Giuseppe

2015-06-10

Blood-mediated nanoparticle delivery is a new and growing field in the development of therapeutics and diagnostics. Nanoparticle properties such as size, shape and surface chemistry can be controlled to improve their performance in biological systems. This enables modulation of immune system interactions, blood clearance profile and interaction with target cells, thereby aiding effective delivery of cargo within cells or tissues. Their ability to target and enter tissues from the blood is highly dependent on their behaviour under blood flow. Here we have produced an agent-based model of nanoparticle behaviour under blood flow in capillaries. We demonstrate that red blood cells are highly important for effective nanoparticle distribution within capillaries. Furthermore, we use this model to demonstrate how nanoparticle size can selectively target tumour tissue over normal tissue. We demonstrate that the polydispersity of nanoparticle populations is an important consideration in achieving optimal specificity and to avoid off-target effects. In future this model could be used for informing new nanoparticle design and to predict general and specific uptake properties under blood flow.

Grid refinement in Cartesian coordinates for groundwater flow models using the divergence theorem and Taylor's series.

PubMed

Mansour, M M; Spink, A E F

2013-01-01

Grid refinement is introduced in a numerical groundwater model to increase the accuracy of the solution over local areas without compromising the run time of the model. Numerical methods developed for grid refinement suffered certain drawbacks, for example, deficiencies in the implemented interpolation technique; the non-reciprocity in head calculations or flow calculations; lack of accuracy resulting from high truncation errors, and numerical problems resulting from the construction of elongated meshes. A refinement scheme based on the divergence theorem and Taylor's expansions is presented in this article. This scheme is based on the work of De Marsily (1986) but includes more terms of the Taylor's series to improve the numerical solution. In this scheme, flow reciprocity is maintained and high order of refinement was achievable. The new numerical method is applied to simulate groundwater flows in homogeneous and heterogeneous confined aquifers. It produced results with acceptable degrees of accuracy. This method shows the potential for its application to solving groundwater heads over nested meshes with irregular shapes. © 2012, British Geological Survey © NERC 2012. Ground Water © 2012, National GroundWater Association.

Recharge Area, Base-Flow and Quick-Flow Discharge Rates and Ages, and General Water Quality of Big Spring in Carter County, Missouri, 2000-04

USGS Publications Warehouse

Imes, Jeffrey L.; Plummer, Niel; Kleeschulte, Michael J.; Schumacher, John G.

2007-01-01

Exploration for lead deposits has occurred in a mature karst area of southeast Missouri that is highly valued for its scenic beauty and recreational opportunities. The area contains the two largest springs in Missouri (Big Spring and Greer Spring), both of which flow into federally designated scenic rivers. Concerns about potential mining effects on the area ground water and aquatic biota prompted an investigation of Big Spring. Water-level measurements made during 2000 helped define the recharge area of Big Spring, Greer Spring, Mammoth Spring, and Boze Mill Spring. The data infer two distinct potentiometric surfaces. The shallow potentiometric surface, where the depth-to-water is less than about 250 feet, tends to mimic topographic features and is strongly controlled by streams. The deep potentiometric surface, where the depth-to-water is greater than about 250 feet represents ground-water hydraulic heads within the more mature karst areas. A highly permeable zone extends about 20 mile west of Big Spring toward the upper Hurricane Creek Basin. Deeper flowing water in the Big Spring recharge area is directed toward this permeable zone. The estimated sizes of the spring recharge areas are 426 square miles for Big Spring, 352 square miles for Greer Spring, 290 square miles for Mammoth Spring, and 54 square miles for Boze Mill Spring. A discharge accumulation curve using Big Spring daily mean discharge data shows no substantial change in the discharge pattern of Big Spring during the period of record (water years 1922 through 2004). The extended periods when the spring flow deviated from the trend line can be attributed to prolonged departures from normal precipitation. The maximum possible instantaneous flow from Big Spring has not been adequately defined because of backwater effects from the Current River during high-flow conditions. Physical constraints within the spring conduit system may restrict its maximum flow. The largest discharge measured at Big Spring during the period of record (water years 1922 through 2004) was 1,170 cubic feet per second on December 7, 1982. The daily mean water temperature of Big Spring was monitored during water years 2001 through 2004 and showed little variability, ranging from 13 to 15? C (degree Celsius). Water temperatures generally vary less than 1? C throughout the year. The warmest temperatures occur during October and November and decrease until April, indicating Big Spring water temperature does show a slight seasonal variation. The use of the traditional hydrograph separation program HYSEP to determine the base flow and quick flow or runoff components at Big Spring failed to yield base-flow and quick-flow discharge curves that matched observations of spring characteristics. Big Spring discharge data were used in combination with specific conductance data to develop an improved hydrograph separation method for the spring. The estimated annual mean quick flow ranged from 15 to 48 cubic feet per second for the HYSEP analysis and ranged from 26 to 154 cubic feet per second for the discharge and specific conductance method for water years 2001 to 2004. Using the discharge and specific conductance method, the estimated base-flow component rises abruptly as the spring hydrograph rises, attains a peak value on the same day as the discharge peak, and then declines abruptly from its peak value. Several days later, base flow begins to increase again at an approximately linear trend, coinciding with the time at which the percentage of quick flow has reached a maximum after each recharge-induced discharge peak. The interval between the discharge peak and the peak in percentage quick flow ranges from 8 to 11 days for seven hydrograph peaks, consistent with quick-flow traveltime estimates by dye-trace tests from the mature karst Hurricane Creek Basin in the central part of the recharge area. Concentrations of environmental tracers chlorofluorocarbons (CFCs: CFC-11, CFC-12, CFC-113)

Investigation of the relative effects of vascular branching structure and gravity on pulmonary arterial blood flow heterogeneity via an image-based computational model.

PubMed

Burrowes, Kelly S; Hunter, Peter J; Tawhai, Merryn H

2005-11-01

A computational model of blood flow through the human pulmonary arterial tree has been developed to investigate the relative influence of branching structure and gravity on blood flow distribution in the human lung. Geometric models of the largest arterial vessels and lobar boundaries were first derived using multidetector row x-ray computed tomography (MDCT) scans. Further accompanying arterial vessels were generated from the MDCT vessel endpoints into the lobar volumes using a volume-filling branching algorithm. Equations governing the conservation of mass and momentum were solved within the geometric model to calculate pressure, velocity, and vessel radius. Blood flow results in the anatomically based model, with and without gravity, and in a symmetric geometric model were compared to investigate their relative contributions to blood flow heterogeneity. Results showed a persistent blood flow gradient and flow heterogeneity in the absence of gravitational forces in the anatomically based model. Comparison with flow results in the symmetric model revealed that the asymmetric vascular branching structure was largely responsible for producing this heterogeneity. Analysis of average results in varying slice thicknesses illustrated a clear flow gradient because of gravity in "lower resolution" data (thicker slices), but on examination of higher resolution data, a trend was less obvious. Results suggest that although gravity does influence flow distribution, the influence of the tree branching structure is also a dominant factor. These results are consistent with high-resolution experimental studies that have demonstrated gravity to be only a minor determinant of blood flow distribution.

Vulnerability assessment of groundwater-dependent ecosystems based on integrated groundwater flow modell construction

NASA Astrophysics Data System (ADS)

Tóth, Ádám; Simon, Szilvia; Galsa, Attila; Havril, Timea; Monteiro Santos, Fernando A.; Müller, Imre; Mádl-Szőnyi, Judit

2017-04-01

Groundwater-dependent ecosystems (GDEs) are highly influenced by the amount of groundwater, seasonal variation of precipitation and consequent water table fluctuation and also the anthropogenic activities. They can be regarded as natural surface manifestations of the flowing groundwater. The preservation of environment and biodiversity of these GDEs is an important issue worldwide, however, the water management policy and action plan could not be constructed in absense of proper hydrogeological knowledge. The concept of gravity-driven regional groundwater flow could aid the understanding of flow pattern and interpretation of environmental processes and conditions. Unless the required well data are available, the geological-hydrogeological numerical model of the study area cannot be constructed based only on borehole information. In this case, spatially continuous geophysical data can support groundwater flow model building: systematically combined geophysical methods can provide model input. Integration of lithostratigraphic, electrostratigraphic and hydrostratigraphic information could aid groundwater flow model construction: hydrostratigraphic units and their hydraulic behaviour, boundaries and geometry can be obtained. Groundwater-related natural manifestations, such as GDEs, can be explained with the help of the revealed flow pattern and field mapping of features. Integrated groundwater flow model construction for assessing the vulnerability of GDEs was presented via the case study of the geologically complex area of Tihany Peninsula, Hungary, with the aims of understanding the background and occurrence of groundwater-related environmental phenomena, surface water-groundwater interaction, and revealing the potential effect of anthropogenic activity and climate change. In spite of its important and protected status, fluid flow model of the area, which could support water management and natural protection policy, had not been constructed previously. The 3D groundwater flow model, which was based on the scarce geologic information and the electromagnetic geophysical results, could answer the subsurface hydraulic connection between GDEs. Moreover, the gravity-driven regional groundwater flow concept could help to interpret the hydraulically nested flow systems (local and intermediate). Validation of numerical simulation by natural surface conditions and phenomena was performed. Consequently, the position of wetlands, their vegetation type, discharge features and induced landslides were explained as environmental imprints of groundwater. Anthropogenic activities and climate change have great impact on groundwater. Since the GDEs are fed by local flow systems, the impact of climate change and anthropogenic activities could be notable, therefore the highly vulnerable wetlands have to be in focus of water management and natural conservation policy.

Simulation of ground-water flow and evaluation of water-management alternatives in the upper Charles River basin, eastern Massachusetts

USGS Publications Warehouse

DeSimone, Leslie A.; Walter, Donald A.; Eggleston, John R.; Nimiroski, Mark T.

2002-01-01

Ground water is the primary source of drinking water for towns in the upper Charles River Basin, an area of 105 square miles in eastern Massachusetts that is undergoing rapid growth. The stratified-glacial aquifers in the basin are high yield, but also are thin, discontinuous, and in close hydraulic connection with streams, ponds, and wetlands. Water withdrawals averaged 10.1 million gallons per day in 1989?98 and are likely to increase in response to rapid growth. These withdrawals deplete streamflow and lower pond levels. A study was conducted to develop tools for evaluating water-management alternatives at the regional scale in the basin. Geologic and hydrologic data were compiled and collected to characterize the ground- and surface-water systems. Numerical flow modeling techniques were applied to evaluate the effects of increased withdrawals and altered recharge on ground-water levels, pond levels, and stream base flow. Simulation-optimization methods also were applied to test their efficacy for management of multiple water-supply and water-resource needs. Steady-state and transient ground-water-flow models were developed using the numerical modeling code MODFLOW-2000. The models were calibrated to 1989?98 average annual conditions of water withdrawals, water levels, and stream base flow. Model recharge rates were varied spatially, by land use, surficial geology, and septic-tank return flow. Recharge was changed during model calibration by means of parameter-estimation techniques to better match the estimated average annual base flow; area-weighted rates averaged 22.5 inches per year for the basin. Water withdrawals accounted for about 7 percent of total simulated flows through the stream-aquifer system and were about equal in magnitude to model-calculated rates of ground-water evapotranspiration from wetlands and ponds in aquifer areas. Water withdrawals as percentages of total flow varied spatially and temporally within an average year; maximum values were 12 to 13 percent of total annual flow in some subbasins and of total monthly flow throughout the basin in summer and early fall. Water-management alternatives were evaluated by simulating hypothetical scenarios of increased withdrawals and altered recharge for average 1989?98 conditions with the flow models. Increased withdrawals to maximum State-permitted levels would result in withdrawals of about 15 million gallons per day, or about 50 percent more than current withdrawals. Model-calculated effects of these increased withdrawals included reductions in stream base flow that were greatest (as a percentage of total flow) in late summer and early fall. These reductions ranged from less than 5 percent to more than 60 percent of model-calculated 1989?98 base flow along reaches of the Charles River and major tributaries during low-flow periods. Reductions in base flow generally were comparable to upstream increases in withdrawals, but were slightly less than upstream withdrawals in areas where septic-system return flow was simulated. Increased withdrawals also increased the proportion of wastewater in the Charles River downstream of treatment facilities. The wastewater component increased downstream from a treatment facility in Milford from 80 percent of September base flow under 1989?98 conditions to 90 percent of base flow, and from 18 to 27 percent of September base flow downstream of a treatment facility in Medway. In another set of hypothetical scenarios, additional recharge equal to the transfer of water out of a typical subbasin by sewers was found to increase model-calculated base flows by about 12 percent of model-calculated base flows. Addition of recharge equal to that available from artificial recharge of residential rooftop runoff had smaller effects, augmenting simulated September base flow by about 3 percent. Simulation-optimization methods were applied to an area near Populatic Pond and the confluence of the Mill and Charles Rivers in Franklin,

Unsteady flow motions in the supraglottal region during phonation

NASA Astrophysics Data System (ADS)

Luo, Haoxiang; Dai, Hu

2008-11-01

The highly unsteady flow motions in the larynx are not only responsible for producing the fundamental frequency tone in phonation, but also have a significant contribution to the broadband noise in the human voice. In this work, the laryngeal flow is modeled either as an incompressible pulsatile jet confined in a two-dimensional channel, or a pressure-driven flow modulated by a pair of viscoelastic vocal folds through the flow--structure interaction. The flow in the supraglottal region is found to be dominated by large-scale vortices whose unsteady motions significantly deflect the glottal jet. In the flow--structure interaction, a hybrid model based on the immersed-boundary method is developed to simulate the flow-induced vocal fold vibration, which involves a three-dimensional vocal fold prototype and a two-dimensional viscous flow. Both the flow behavior and the vibratory characteristics of the vocal folds will be presented.

Flash chemistry: flow microreactor synthesis based on high-resolution reaction time control.

PubMed

Yoshida, Jun-ichi

2010-10-01

This article addresses a fascinating aspect of flash chemistry, high-resolution reaction-time control by virtue of a flow microreactor system, and its applications. The length of time that the solution remains inside the reactor is called the residence time. The residence time between the addition of a reagent and that of a quenching agent or the next reagent in a flow microreactor is the reaction time, and the reaction time can be greatly reduced by adjusting the length of a reaction channel in a flow microreactor. This feature is quite effective for conducting reactions involving short-lived reactive intermediates. A reactive species can be generated and transferred to another location to be used in the next reaction before it decomposes by adjusting the residence time in the millisecond to second timescale. The principle of such high-resolution reaction-time control, which can be achieved only by flow microreactors, and its applications to synthetic reactions including Swern-Moffatt-type oxidation, as well as the generation and reactions of aryllithium compounds bearing electrophilic substituents, such as alkoxycarbonyl groups, are presented. Integration of such reactions using integrated flow microreactor systems is also demonstrated. © 2010 The Japan Chemical Journal Forum and Wiley Periodicals, Inc.

Large Eddy Simulation of "turbulent-like" flow in intracranial aneurysms

NASA Astrophysics Data System (ADS)

Khan, Muhammad Owais; Chnafa, Christophe; Steinman, David A.; Mendez, Simon; Nicoud, Franck

2016-11-01

Hemodynamic forces are thought to contribute to pathogenesis and rupture of intracranial aneurysms (IA). Recent high-resolution patient-specific computational fluid dynamics (CFD) simulations have highlighted the presence of "turbulent-like" flow features, characterized by transient high-frequency flow instabilities. In-vitro studies have shown that such "turbulent-like" flows can lead to lack of endothelial cell orientation and cell depletion, and thus, may also have relevance to IA rupture risk assessment. From a modelling perspective, previous studies have relied on DNS to resolve the small-scale structures in these flows. While accurate, DNS is clinically infeasible due to high computational cost and long simulation times. In this study, we present the applicability of LES for IAs using a LES/blood flow dedicated solver (YALES2BIO) and compare against respective DNS. As a qualitative analysis, we compute time-averaged WSS and OSI maps, as well as, novel frequency-based WSS indices. As a quantitative analysis, we show the differences in POD eigenspectra for LES vs. DNS and wavelet analysis of intra-saccular velocity traces. Differences in two SGS models (i.e. Dynamic Smagorinsky vs. Sigma) are also compared against DNS, and computational gains of LES are discussed.

Comparison of Themodynamic and Transport Property Models for Computing Equilibrium High Enthalpy Flows

NASA Astrophysics Data System (ADS)

Ramasahayam, Veda Krishna Vyas; Diwakar, Anant; Bodi, Kowsik

2017-11-01

To study the flow of high temperature air in vibrational and chemical equilibrium, accurate models for thermodynamic state and transport phenomena are required. In the present work, the performance of a state equation model and two mixing rules for determining equilibrium air thermodynamic and transport properties are compared with that of curve fits. The thermodynamic state model considers 11 species which computes flow chemistry by an iterative process and the mixing rules considered for viscosity are Wilke and Armaly-Sutton. The curve fits of Srinivasan, which are based on Grabau type transition functions, are chosen for comparison. A two-dimensional Navier-Stokes solver is developed to simulate high enthalpy flows with numerical fluxes computed by AUSM+-up. The accuracy of state equation model and curve fits for thermodynamic properties is determined using hypersonic inviscid flow over a circular cylinder. The performance of mixing rules and curve fits for viscosity are compared using hypersonic laminar boundary layer prediction on a flat plate. It is observed that steady state solutions from state equation model and curve fits match with each other. Though curve fits are significantly faster the state equation model is more general and can be adapted to any flow composition.

Navigating the flow: individual and continuum models for homing in flowing environments.

PubMed

Painter, Kevin J; Hillen, Thomas

2015-11-06

Navigation for aquatic and airborne species often takes place in the face of complicated flows, from persistent currents to highly unpredictable storms. Hydrodynamic models are capable of simulating flow dynamics and provide the impetus for much individual-based modelling, in which particle-sized individuals are immersed into a flowing medium. These models yield insights on the impact of currents on population distributions from fish eggs to large organisms, yet their computational demands and intractability reduce their capacity to generate the broader, less parameter-specific, insights allowed by traditional continuous approaches. In this paper, we formulate an individual-based model for navigation within a flowing field and apply scaling to derive its corresponding macroscopic and continuous model. We apply it to various movement classes, from drifters that simply go with the flow to navigators that respond to environmental orienteering cues. The utility of the model is demonstrated via its application to 'homing' problems and, in particular, the navigation of the marine green turtle Chelonia mydas to Ascension Island. © 2015 The Author(s).

Highly sensitive miniature fluidic flowmeter based on an FBG heated by Co²⁺-doped fiber.

PubMed

Liu, Zhengyong; Htein, Lin; Cheng, Lun-Kai; Martina, Quincy; Jansen, Rob; Tam, Hwa-Yaw

2017-02-20

In this paper, we present a miniature fluidic flow sensor based on a short fiber Bragg grating inscribed in a single mode fiber and heated by Co²⁺-doped multimode fibers. The proposed flow sensor was employed to measure the flow rates of oil and water, showing good sensitivity of 0.339 nm/(m/s) and 0.578 nm/(m/s) for water and oil, flowing at v = 0.2 m/s. The sensitivity can be increased with higher laser power launched to the Co²⁺-doped multimode fibers. A small flow rate of 0.005 m/s and 0.002 m/s can be distinguished for a particular phase of water or oil, respectively, at a certain laser power (i.e. ~1.43W). The flow sensor can measure volume speed up to 30 L/min, which is limited by the test rig. The experimental results show that the sensor can discriminate slight variation of flow rates as small as 0.002m/s.

Optofluidic bioimaging platform for quantitative phase imaging of lab on a chip devices using digital holographic microscopy.

PubMed

Pandiyan, Vimal Prabhu; John, Renu

2016-01-20

We propose a versatile 3D phase-imaging microscope platform for real-time imaging of optomicrofluidic devices based on the principle of digital holographic microscopy (DHM). Lab-on-chip microfluidic devices fabricated on transparent polydimethylsiloxane (PDMS) and glass substrates have attained wide popularity in biological sensing applications. However, monitoring, visualization, and characterization of microfluidic devices, microfluidic flows, and the biochemical kinetics happening in these devices is difficult due to the lack of proper techniques for real-time imaging and analysis. The traditional bright-field microscopic techniques fail in imaging applications, as the microfluidic channels and the fluids carrying biological samples are transparent and not visible in bright light. Phase-based microscopy techniques that can image the phase of the microfluidic channel and changes in refractive indices due to the fluids and biological samples present in the channel are ideal for imaging the fluid flow dynamics in a microfluidic channel at high resolutions. This paper demonstrates three-dimensional imaging of a microfluidic device with nanometric depth precisions and high SNR. We demonstrate imaging of microelectrodes of nanometric thickness patterned on glass substrate and the microfluidic channel. Three-dimensional imaging of a transparent PDMS optomicrofluidic channel, fluid flow, and live yeast cell flow in this channel has been demonstrated using DHM. We also quantify the average velocity of fluid flow through the channel. In comparison to any conventional bright-field microscope, the 3D depth information in the images illustrated in this work carry much information about the biological system under observation. The results demonstrated in this paper prove the high potential of DHM in imaging optofluidic devices; detection of pathogens, cells, and bioanalytes on lab-on-chip devices; and in studying microfluidic dynamics in real time based on phase changes.

Device specific analysis of neonatal aortic outflow cannula jet flows for improved cardiopulmonary bypass hemodynamics

NASA Astrophysics Data System (ADS)

Menon, Prahlad; Sotiropoulos, Fotis; Undar, Akif; Pekkan, Kerem

2011-11-01

Hemodynamically efficient aortic outflow cannulae can provide high blood volume flow rates at low exit force during extracorporeal circulation in pediatric or neonatal cardiopulmonary bypass repairs. Furthermore, optimal hemolytic aortic insertion configurations can significantly reduce risk of post-surgical neurological complications and developmental defects in the young patient. The methodology and results presented in this study serve as a baseline for design of superior aortic outflow cannulae based on a novel paradigm of characterizing jet-flows at different flow regimes. In-silico evaluations of multiple cannula tips were used to delineate baseline hemodynamic performance of the popular pediatric cannula tips in an experimental cuboidal test-rig, using PIV. High resolution CFD jet-flow simulations performed for various cannula tips in the cuboidal test-rig as well as in-vivo insertion configurations have suggested the existence of optimal surgically relevant characteristics such as cannula outflow angle and insertion depth for improved hemodynamic performance during surgery. Improved cannula tips were designed with internal flow-control features for decreased blood damage and increased permissible flow rates.

A Geochemical Mass-Balance Method for Base-Flow Separation, Upper Hillsborough River Watershed, West-Central Florida, 2003-2005 and 2009

USGS Publications Warehouse

Kish, G.R.; Stringer, C.E.; Stewart, M.T.; Rains, M.C.; Torres, A.E.

2010-01-01

Geochemical mass-balance (GMB) and conductivity mass-balance (CMB) methods for hydrograph separation were used to determine the contribution of base flow to total stormflow at two sites in the upper Hillsborough River watershed in west-central Florida from 2003-2005 and at one site in 2009. The chemical and isotopic composition of streamflow and precipitation was measured during selected local and frontal low- and high-intensity storm events and compared to the geochemical and isotopic composition of groundwater. Input for the GMB method included cation, anion, and stable isotope concentrations of surface water and groundwater, whereas input for the CMB method included continuous or point-sample measurement of specific conductance. The surface water is a calcium-bicarbonate type water, which closely resembles groundwater geochemically, indicating that much of the surface water in the upper Hillsborough River basin is derived from local groundwater discharge. This discharge into the Hillsborough River at State Road 39 and at Hillsborough River State Park becomes diluted by precipitation and runoff during the wet season, but retains the calcium-bicarbonate characteristics of Upper Floridan aquifer water. Field conditions limited the application of the GMB method to low-intensity storms but the CMB method was applied to both low-intensity and high-intensity storms. The average contribution of base flow to total discharge for all storms ranged from 31 to 100 percent, whereas the contribution of base flow to total discharge during peak discharge periods ranged from less than 10 percent to 100 percent. Although calcium, magnesium, and silica were consistent markers of Upper Floridan aquifer chemistry, their use in calculating base flow by the GMB method was limited because the frequency of point data collected in this study was not sufficient to capture the complete hydrograph from pre-event base-flow to post-event base-flow concentrations. In this study, pre-event water represented somewhat diluted groundwater. Streamflow conductivity integrates the concentrations of the major ions, and the logistics of acquiring specific conductance at frequent time intervals are less complicated than data collection, sample processing, shipment, and analysis of water samples in a laboratory. The acquisition of continuous specific conductance data reduces uncertainty associated with less-frequently collected geochemical point data.

Panorama of Reconstruction of Skull Base Defects: From Traditional Open to Endonasal Endoscopic Approaches, from Free Grafts to Microvascular Flaps

PubMed Central

Reyes, Camilo; Mason, Eric; Solares, C. Arturo

2014-01-01

Introduction A substantial body of literature has been devoted to the distinct characteristics and surgical options to repair the skull base. However, the skull base is an anatomically challenging location that requires a three-dimensional reconstruction approach. Furthermore, advances in endoscopic skull base surgery encompass a wide range of surgical pathology, from benign tumors to sinonasal cancer. This has resulted in the creation of wide defects that yield a new challenge in skull base reconstruction. Progress in technology and imaging has made this approach an internationally accepted method to repair these defects. Objectives Discuss historical developments and flaps available for skull base reconstruction. Data Synthesis Free grafts in skull base reconstruction are a viable option in small defects and low-flow leaks. Vascularized flaps pose a distinct advantage in large defects and high-flow leaks. When open techniques are used, free flap reconstruction techniques are often necessary to repair large entry wound defects. Conclusions Reconstruction of skull base defects requires a thorough knowledge of surgical anatomy, disease, and patient risk factors associated with high-flow cerebrospinal fluid leaks. Various reconstruction techniques are available, from free tissue grafting to vascularized flaps. Possible complications that can befall after these procedures need to be considered. Although endonasal techniques are being used with increasing frequency, open techniques are still necessary in selected cases. PMID:25992142

Analysis of flow patterns in a patient-specific aortic dissection model.

PubMed

Cheng, Z; Tan, F P P; Riga, C V; Bicknell, C D; Hamady, M S; Gibbs, R G J; Wood, N B; Xu, X Y

2010-05-01

Aortic dissection is the most common acute catastrophic event affecting the thoracic aorta. The majority of patients presenting with an uncomplicated type B dissection are treated medically, but 25% of these patients develop subsequent aneurysmal dilatation of the thoracic aorta. This study aimed at gaining more detailed knowledge of the flow phenomena associated with this condition. Morphological features and flow patterns in a dissected aortic segment of a presurgery type B dissection patient were analyzed based on computed tomography images acquired from the patient. Computational simulations of blood flow in the patient-specific model were performed by employing a correlation-based transitional version of Menter's hybrid k-epsilon/k-omega shear stress transport turbulence model implemented in ANSYS CFX 11. Our results show that the dissected aorta is dominated by locally highly disturbed, and possibly turbulent, flow with strong recirculation. A significant proportion (about 80%) of the aortic flow enters the false lumen, which may further increase the dilatation of the aorta. High values of wall shear stress have been found around the tear on the true lumen wall, perhaps increasing the likelihood of expanding the tear. Turbulence intensity in the tear region reaches a maximum of 70% at midsystolic deceleration phase. Incorporating the non-Newtonian behavior of blood into the same transitional flow model has yielded a slightly lower peak wall shear stress and higher maximum turbulence intensity without causing discernible changes to the distribution patterns. Comparisons between the laminar and turbulent flow simulations show a qualitatively similar distribution of wall shear stress but a significantly higher magnitude with the transitional turbulence model.

The Role of Forests in Regulating the River Flow Regime of Large Basins of the World

NASA Astrophysics Data System (ADS)

Salazar, J. F.; Villegas, J. C.; Mercado-Bettin, D. A.; Rodríguez, E.

2016-12-01

Many natural and social phenomena depend on river flow regimes that are being altered by global change. Understanding the mechanisms behind such alterations is crucial for predicting river flow regimes in a changing environment. Here we explore potential linkages between the presence of forests and the capacity of river basins for regulating river flows. Regulation is defined here as the capacity of river basins to attenuate the amplitude of the river flow regime, that is to reduce the difference between high and low flows. We first use scaling theory to show how scaling properties of observed river flows can be used to classify river basins as regulated or unregulated. This parsimonious classification is based on a physical interpretation of the scaling properties (particularly the scaling exponents) that is novel (most previous studies have focused on the interpretation of the scaling exponents for floods only), and widely-applicable to different basins (the only assumption is that river flows in a given river basin exhibit scaling properties through well-known power laws). Then we show how this scaling framework can be used to explore global-change-induced temporal variations in the regulation capacity of river basins. Finally, we propose a conceptual hypothesis (the "Forest reservoir concept") to explain how large-scale forests can exert important effects on the long-term water balance partitioning and regulation capacity of large basins of the world. Our quantitative results are based on data analysis (river flows and land cover features) from 22 large basins of the world, with emphasis in the Amazon river and its main tributaries. Collectively, our findings support the hypothesis that forest cover enhances the capacity of large river basins to maintain relatively high mean river flows, as well as to regulate (ameliorate) extreme river flows. Advancing towards this quantitative understanding of the relation between forest cover and river flow regimes is crucial for water management- and land cover-related decisions.

The Role of Forests in Regulating the River Flow Regime of Large Basins of the World

NASA Astrophysics Data System (ADS)

Salazar, J. F.; Villegas, J. C.; Mercado-Bettin, D. A.; Rodríguez, E.

2017-12-01

Many natural and social phenomena depend on river flow regimes that are being altered by global change. Understanding the mechanisms behind such alterations is crucial for predicting river flow regimes in a changing environment. Here we explore potential linkages between the presence of forests and the capacity of river basins for regulating river flows. Regulation is defined here as the capacity of river basins to attenuate the amplitude of the river flow regime, that is to reduce the difference between high and low flows. We first use scaling theory to show how scaling properties of observed river flows can be used to classify river basins as regulated or unregulated. This parsimonious classification is based on a physical interpretation of the scaling properties (particularly the scaling exponents) that is novel (most previous studies have focused on the interpretation of the scaling exponents for floods only), and widely-applicable to different basins (the only assumption is that river flows in a given river basin exhibit scaling properties through well-known power laws). Then we show how this scaling framework can be used to explore global-change-induced temporal variations in the regulation capacity of river basins. Finally, we propose a conceptual hypothesis (the "Forest reservoir concept") to explain how large-scale forests can exert important effects on the long-term water balance partitioning and regulation capacity of large basins of the world. Our quantitative results are based on data analysis (river flows and land cover features) from 22 large basins of the world, with emphasis in the Amazon river and its main tributaries. Collectively, our findings support the hypothesis that forest cover enhances the capacity of large river basins to maintain relatively high mean river flows, as well as to regulate (ameliorate) extreme river flows. Advancing towards this quantitative understanding of the relation between forest cover and river flow regimes is crucial for water management- and land cover-related decisions.

High Resolution Time Series of Plankton Communities: From Early Warning of Harmful Blooms to Sentinels of Climate Change

NASA Astrophysics Data System (ADS)

Sosik, H. M.; Campbell, L.; Olson, R. J.

2016-02-01

The combination of ocean observatory infrastructure and automated submersible flow cytometry provides an unprecedented capability for sustained high resolution time series of plankton, including taxa that are harmful or early indicators of ecosystem response to environmental change. On-going time series produced with the FlowCytobot series of instruments document important ways this challenge is already being met for phytoplankton and microzooplankton. FlowCytobot and Imaging FlowCytobot use a combination of laser-based scattering and fluorescence measurements and video imaging of individual particles to enumerate and characterize cells ranging from picocyanobacteria to large chaining-forming diatoms. Over a decade of observations at the Martha's Vineyard Coastal Observatory (MVCO), a cabled facility on the New England Shelf, have been compiled from repeated instrument deployments, typically 6 months or longer in duration. These multi-year high resolution (hourly to daily) time series are providing new insights into dynamics of community structure such as blooms, seasonality, and multi-year trends linked to regional climate-related variables. Similar observations in Texas coastal waters at the Texas Observatory for Algal Succession Time series (TOAST) have repeatedly provided early warning of harmful algal bloom events that threaten human and ecosystem health. As coastal ocean observing systems mature and expand, the continued integration of these type of detailed observations of the plankton will provide unparalleled information about variability and patterns of change at the base of the marine food webs, with direct implications for informed ecosystem-based management.

Absorption Filter Based Optical Diagnostics in High Speed Flows

NASA Technical Reports Server (NTRS)

Samimy, Mo; Elliott, Gregory; Arnette, Stephen

1996-01-01

Two major regimes where laser light scattered by molecules or particles in a flow contains significant information about the flow are Mie scattering and Rayleigh scattering. Mie scattering is used to obtain only velocity information, while Rayleigh scattering can be used to measure both the velocity and the thermodynamic properties of the flow. Now, recently introduced (1990, 1991) absorption filter based diagnostic techniques have started a new era in flow visualization, simultaneous velocity and thermodynamic measurements, and planar velocity measurements. Using a filtered planar velocimetry (FPV) technique, we have modified the optically thick iodine filter profile of Miles, et al., and used it in the pressure-broaden regime which accommodates measurements in a wide range of velocity applications. Measuring velocity and thermodynamic properties simultaneously, using absorption filtered based Rayleigh scattering, involves not only the measurement of the Doppler shift, but also the spectral profile of the Rayleigh scattering signal. Using multiple observation angles, simultaneous measurement of one component velocity and thermodynamic properties in a supersonic jet were measured. Presently, the technique is being extended for simultaneous measurements of all three components of velocity and thermodynamic properties.

Processing methods for photoacoustic Doppler flowmetry with a clinical ultrasound scanner

NASA Astrophysics Data System (ADS)

Bücking, Thore M.; van den Berg, Pim J.; Balabani, Stavroula; Steenbergen, Wiendelt; Beard, Paul C.; Brunker, Joanna

2018-02-01

Photoacoustic flowmetry (PAF) based on time-domain cross correlation of photoacoustic signals is a promising technique for deep tissue measurement of blood flow velocity. Signal processing has previously been developed for single element transducers. Here, the processing methods for acoustic resolution PAF using a clinical ultrasound transducer array are developed and validated using a 64-element transducer array with a -6 dB detection band of 11 to 17 MHz. Measurements were performed on a flow phantom consisting of a tube (580 μm inner diameter) perfused with human blood flowing at physiological speeds ranging from 3 to 25 mm / s. The processing pipeline comprised: image reconstruction, filtering, displacement detection, and masking. High-pass filtering and background subtraction were found to be key preprocessing steps to enable accurate flow velocity estimates, which were calculated using a cross-correlation based method. In addition, the regions of interest in the calculated velocity maps were defined using a masking approach based on the amplitude of the cross-correlation functions. These developments enabled blood flow measurements using a transducer array, bringing PAF one step closer to clinical applicability.

Viscid-inviscid interaction associated with incompressible flow past wedges at high Reynolds number

NASA Technical Reports Server (NTRS)

Warpinski, N. R.; Chow, W. L.

1977-01-01

An analytical method is suggested for the study of the viscid inviscid interaction associated with incompressible flow past wedges with arbitrary angles. It is shown that the determination of the nearly constant pressure (base pressure) prevailing within the near wake is really the heart of the problem, and the pressure can only be established from these interactive considerations. The basic free streamline flow field is established through two discrete parameters which adequately describe the inviscid flow around the body and the wake. The viscous flow processes such as the boundary layer buildup, turbulent jet mixing, and recompression are individually analyzed and attached to the inviscid flow in the sense of the boundary layer concept. The interaction between the viscous and inviscid streams is properly displayed by the fact that the aforementioned discrete parameters needed for the inviscid flow are determined by the viscous flow condition at the point of reattachment. It is found that the reattachment point behaves as a saddle point singularity for the system of equations describing the recompressive viscous flow processes, and this behavior is exploited for the establishment of the overall flow field. Detailed results such as the base pressure, pressure distributions on the wedge, and the geometry of the wake are determined as functions of the wedge angle.

A high-order 3D spectral difference solver for simulating flows about rotating geometries

NASA Astrophysics Data System (ADS)

Zhang, Bin; Liang, Chunlei

2017-11-01

Fluid flows around rotating geometries are ubiquitous. For example, a spinning ping pong ball can quickly change its trajectory in an air flow; a marine propeller can provide enormous amount of thrust to a ship. It has been a long-time challenge to accurately simulate these flows. In this work, we present a high-order and efficient 3D flow solver based on unstructured spectral difference (SD) method and a novel sliding-mesh method. In the SD method, solution and fluxes are reconstructed using tensor products of 1D polynomials and the equations are solved in differential-form, which leads to high-order accuracy and high efficiency. In the sliding-mesh method, a computational domain is decomposed into non-overlapping subdomains. Each subdomain can enclose a geometry and can rotate relative to its neighbor, resulting in nonconforming sliding interfaces. A curved dynamic mortar approach is designed for communication on these interfaces. In this approach, solutions and fluxes are projected from cell faces to mortars to compute common values which are then projected back to ensures continuity and conservation. Through theoretical analysis and numerical tests, it is shown that this solver is conservative, free-stream preservative, and high-order accurate in both space and time.

Probability modeling of high flow extremes in Yingluoxia watershed, the upper reaches of Heihe River basin

NASA Astrophysics Data System (ADS)

Li, Zhanling; Li, Zhanjie; Li, Chengcheng

2014-05-01

Probability modeling of hydrological extremes is one of the major research areas in hydrological science. Most basins in humid and semi-humid south and east of China are concerned for probability modeling analysis of high flow extremes. While, for the inland river basin which occupies about 35% of the country area, there is a limited presence of such studies partly due to the limited data availability and a relatively low mean annual flow. The objective of this study is to carry out probability modeling of high flow extremes in the upper reach of Heihe River basin, the second largest inland river basin in China, by using the peak over threshold (POT) method and Generalized Pareto Distribution (GPD), in which the selection of threshold and inherent assumptions for POT series are elaborated in details. For comparison, other widely used probability distributions including generalized extreme value (GEV), Lognormal, Log-logistic and Gamma are employed as well. Maximum likelihood estimate is used for parameter estimations. Daily flow data at Yingluoxia station from 1978 to 2008 are used. Results show that, synthesizing the approaches of mean excess plot, stability features of model parameters, return level plot and the inherent independence assumption of POT series, an optimum threshold of 340m3/s is finally determined for high flow extremes in Yingluoxia watershed. The resulting POT series is proved to be stationary and independent based on Mann-Kendall test, Pettitt test and autocorrelation test. In terms of Kolmogorov-Smirnov test, Anderson-Darling test and several graphical diagnostics such as quantile and cumulative density function plots, GPD provides the best fit to high flow extremes in the study area. The estimated high flows for long return periods demonstrate that, as the return period increasing, the return level estimates are probably more uncertain. The frequency of high flow extremes exhibits a very slight but not significant decreasing trend from 1978 to 2008, while the intensity of such flow extremes is comparatively increasing especially for the higher return levels.

Time-dependent jet flow and noise computations

NASA Technical Reports Server (NTRS)

Berman, C. H.; Ramos, J. I.; Karniadakis, G. E.; Orszag, S. A.

1990-01-01

Methods for computing jet turbulence noise based on the time-dependent solution of Lighthill's (1952) differential equation are demonstrated. A key element in this approach is a flow code for solving the time-dependent Navier-Stokes equations at relatively high Reynolds numbers. Jet flow results at Re = 10,000 are presented here. This code combines a computationally efficient spectral element technique and a new self-consistent turbulence subgrid model to supply values for Lighthill's turbulence noise source tensor.

Label-free high-throughput imaging flow cytometry

NASA Astrophysics Data System (ADS)

Mahjoubfar, A.; Chen, C.; Niazi, K. R.; Rabizadeh, S.; Jalali, B.

2014-03-01

Flow cytometry is an optical method for studying cells based on their individual physical and chemical characteristics. It is widely used in clinical diagnosis, medical research, and biotechnology for analysis of blood cells and other cells in suspension. Conventional flow cytometers aim a laser beam at a stream of cells and measure the elastic scattering of light at forward and side angles. They also perform single-point measurements of fluorescent emissions from labeled cells. However, many reagents used in cell labeling reduce cellular viability or change the behavior of the target cells through the activation of undesired cellular processes or inhibition of normal cellular activity. Therefore, labeled cells are not completely representative of their unaltered form nor are they fully reliable for downstream studies. To remove the requirement of cell labeling in flow cytometry, while still meeting the classification sensitivity and specificity goals, measurement of additional biophysical parameters is essential. Here, we introduce an interferometric imaging flow cytometer based on the world's fastest continuous-time camera. Our system simultaneously measures cellular size, scattering, and protein concentration as supplementary biophysical parameters for label-free cell classification. It exploits the wide bandwidth of ultrafast laser pulses to perform blur-free quantitative phase and intensity imaging at flow speeds as high as 10 meters per second and achieves nanometer-scale optical path length resolution for precise measurements of cellular protein concentration.

Implementation of density-based solver for all speeds in the framework of OpenFOAM

NASA Astrophysics Data System (ADS)

Shen, Chun; Sun, Fengxian; Xia, Xinlin

2014-10-01

In the framework of open source CFD code OpenFOAM, a density-based solver for all speeds flow field is developed. In this solver the preconditioned all speeds AUSM+(P) scheme is adopted and the dual time scheme is implemented to complete the unsteady process. Parallel computation could be implemented to accelerate the solving process. Different interface reconstruction algorithms are implemented, and their accuracy with respect to convection is compared. Three benchmark tests of lid-driven cavity flow, flow crossing over a bump, and flow over a forward-facing step are presented to show the accuracy of the AUSM+(P) solver for low-speed incompressible flow, transonic flow, and supersonic/hypersonic flow. Firstly, for the lid driven cavity flow, the computational results obtained by different interface reconstruction algorithms are compared. It is indicated that the one dimensional reconstruction scheme adopted in this solver possesses high accuracy and the solver developed in this paper can effectively catch the features of low incompressible flow. Then via the test cases regarding the flow crossing over bump and over forward step, the ability to capture characteristics of the transonic and supersonic/hypersonic flows are confirmed. The forward-facing step proves to be the most challenging for the preconditioned solvers with and without the dual time scheme. Nonetheless, the solvers described in this paper reproduce the main features of this flow, including the evolution of the initial transient.

Design of a High Voltage Power Supply Providing a Force Field for a Fluid Experiment

NASA Astrophysics Data System (ADS)

Herty, Frank

2005-05-01

As part of the GeoFlow fluid experiment an ac high voltage power supply (HVPS) is used to establish high electrical fields on fluids based on silicon oil. The non- conductive fluid is encapsulated between two spherical electrodes. This experiment cell assembly acts essentially as a capacitive load.The GeoFlow HVPS is an integrated ac high voltage source capable to provide up to 10kVRMS on capacitive loads up to 100pF.This paper presents major design challenges and solutions regarding the high voltage transformer and its driver electronics. Particular high voltage problems like corona effects and dielectric losses are discussed and countermeasures are presented.

High-purity and label-free isolation of circulating tumor cells (CTCs) in a microfluidic platform by using optically-induced-dielectrophoretic (ODEP) force.

PubMed

Huang, Song-Bin; Wu, Min-Hsien; Lin, Yen-Heng; Hsieh, Chia-Hsun; Yang, Chih-Liang; Lin, Hung-Chih; Tseng, Ching-Ping; Lee, Gwo-Bin

2013-04-07

Negative selection-based circulating tumor cell (CTC) isolation is believed valuable to harvest more native, and in particular all possible CTCs without biases relevant to the properties of surface antigens on the CTCs. Under such a cell isolation strategy, however, the CTC purity is normally compromised. To address this issue, this study reports the integration of optically-induced-dielectrophoretic (ODEP) force-based cell manipulation, and a laminar flow regime in a microfluidic platform for the isolation of untreated, and highly pure CTCs after conventional negative selection-based CTC isolation. In the design, six sections of moving light-bar screens were continuously and simultaneously exerted in two parallel laminar flows to concurrently separate the cancer cells from the leukocytes based on their size difference and electric properties. The separated cell populations were further partitioned, delivered, and collected through the two flows. With this approach, the cancer cells can be isolated in a continuous, effective, and efficient manner. In this study, the operating conditions of ODEP for the manipulation of prostate cancer (PC-3) and human oral cancer (OEC-M1) cells, and leukocytes with minor cell aggregation phenomenon were first characterized. Moreover, performances of the proposed method for the isolation of cancer cells were experimentally investigated. The results showed that the presented CTC isolation scheme was able to isolate PC-3 cells or OEC-M1 cells from a leukocyte background with high recovery rate (PC-3 cells: 76-83%, OEC-M1 cells: 61-68%), and high purity (PC-3 cells: 74-82%, OEC-M1 cells: 64-66%) (set flow rate: 0.1 μl min(-1) and sample volume: 1 μl). The latter is beyond what is currently possible in the conventional CTC isolations. Moreover, the viability of isolated cancer cells was evaluated to be as high as 94 ± 2%, and 95 ± 3% for the PC-3, and OEC-M1 cells, respectively. Furthermore, the isolated cancer cells were also shown to preserve their proliferative capability. As a whole, this study has presented an ODEP-based microfluidic platform that is capable of isolating CTCs in a continuous, label-free, cell-friendly, and particularly highly pure manner. All these traits are found particularly meaningful for exploiting the harvested CTCs for the subsequent cell-based, or biochemical assays.

Flow establishment behind blunt bodies at hypersonic speeds in a shock tunnel

NASA Astrophysics Data System (ADS)

Park, G.; Hruschka, R.; Gai, S. L.; Neely, A. J.

2008-11-01

An investigation of flow establishment behind two blunt bodies, a circular cylinder and a 45° half-angle blunted-cone was conducted. Unlike previous studies which relied solely on surface measurements, the present study combines these with unique high-speed visualisation to image the establishment of the flow structure in the base region. Test flows were generated using a free-piston shock tunnel at a nominal Mach number of 10. The freestream unit Reynolds numbers considered were 3.02x105/m and 1.17x106/m at total enthalpies of 13.35MJ/kg and 3.94MJ/kg, respectively. In general, the experiments showed that it takes longer to establish steady heat flux than pressure. The circular cylinder data showed that the near wake had a slight Reynolds number effect, where the size of the near wake was smaller for the high enthalpy flow condition. The blunted-cone data showed that the heat flux and pressures reached steady states in the near wake at similar times for both high and low enthalpy conditions.

Using Selective Drainage Methods to Extract Continuous Surface Flow from 1-Meter Lidar-Derived Digital Elevation Data

USGS Publications Warehouse

Poppenga, Sandra K.; Worstell, Bruce B.; Stoker, Jason M.; Greenlee, Susan K.

2010-01-01

Digital elevation data commonly are used to extract surface flow features. One source for high-resolution elevation data is light detection and ranging (lidar). Lidar can capture a vast amount of topographic detail because of its fine-scale ability to digitally capture the surface of the earth. Because elevation is a key factor in extracting surface flow features, high-resolution lidar-derived digital elevation models (DEMs) provide the detail needed to consistently integrate hydrography with elevation, land cover, structures, and other geospatial features. The U.S. Geological Survey has developed selective drainage methods to extract continuous surface flow from high-resolution lidar-derived digital elevation data. The lidar-derived continuous surface flow network contains valuable information for water resource management involving flood hazard mapping, flood inundation, and coastal erosion. DEMs used in hydrologic applications typically are processed to remove depressions by filling them. High-resolution DEMs derived from lidar can capture much more detail of the land surface than courser elevation data. Therefore, high-resolution DEMs contain more depressions because of obstructions such as roads, railroads, and other elevated structures. The filling of these depressions can significantly affect the DEM-derived surface flow routing and terrain characteristics in an adverse way. In this report, selective draining methods that modify the elevation surface to drain a depression through an obstruction are presented. If such obstructions are not removed from the elevation data, the filling of depressions to create continuous surface flow can cause the flow to spill over an obstruction in the wrong location. Using this modified elevation surface improves the quality of derived surface flow and retains more of the true surface characteristics by correcting large filled depressions. A reliable flow surface is necessary for deriving a consistently connected drainage network, which is important in understanding surface water movement and developing applications for surface water runoff, flood inundation, and erosion. Improved methods are needed to extract continuous surface flow features from high-resolution elevation data based on lidar.

Three-Dimensional Navier-Stokes Method with Two-Equation Turbulence Models for Efficient Numerical Simulation of Hypersonic Flows

NASA Technical Reports Server (NTRS)

Bardina, J. E.

1994-01-01

A new computational efficient 3-D compressible Reynolds-averaged implicit Navier-Stokes method with advanced two equation turbulence models for high speed flows is presented. All convective terms are modeled using an entropy satisfying higher-order Total Variation Diminishing (TVD) scheme based on implicit upwind flux-difference split approximations and arithmetic averaging procedure of primitive variables. This method combines the best features of data management and computational efficiency of space marching procedures with the generality and stability of time dependent Navier-Stokes procedures to solve flows with mixed supersonic and subsonic zones, including streamwise separated flows. Its robust stability derives from a combination of conservative implicit upwind flux-difference splitting with Roe's property U to provide accurate shock capturing capability that non-conservative schemes do not guarantee, alternating symmetric Gauss-Seidel 'method of planes' relaxation procedure coupled with a three-dimensional two-factor diagonal-dominant approximate factorization scheme, TVD flux limiters of higher-order flux differences satisfying realizability, and well-posed characteristic-based implicit boundary-point a'pproximations consistent with the local characteristics domain of dependence. The efficiency of the method is highly increased with Newton Raphson acceleration which allows convergence in essentially one forward sweep for supersonic flows. The method is verified by comparing with experiment and other Navier-Stokes methods. Here, results of adiabatic and cooled flat plate flows, compression corner flow, and 3-D hypersonic shock-wave/turbulent boundary layer interaction flows are presented. The robust 3-D method achieves a better computational efficiency of at least one order of magnitude over the CNS Navier-Stokes code. It provides cost-effective aerodynamic predictions in agreement with experiment, and the capability of predicting complex flow structures in complex geometries with good accuracy.

Method of producing thermally sprayed metallic coating

DOEpatents

Byrnes, Larry Edward [Rochester Hills, MI; Kramer, Martin Stephen [Clarkston, MI; Neiser, Richard A [Albuquerque, NM

2003-08-26

The cylinder walls of light metal engine blocks are thermally spray coated with a ferrous-based coating using an HVOF device. A ferrous-based wire is fed to the HVOF device to locate a tip end of the wire in a high temperature zone of the device. Jet flows of oxygen and gaseous fuel are fed to the high temperature zone and are combusted to generate heat to melt the tip end. The oxygen is oversupplied in relation to the gaseous fuel. The excess oxygen reacts with and burns a fraction of the ferrous-based feed wire in an exothermic reaction to generate substantial supplemental heat to the HVOF device. The molten/combusted metal is sprayed by the device onto the walls of the cylinder by the jet flow of gases.

Nd:YAG Laser-Based Dual-Line Detection Rayleigh Scattering and Current Efforts on UV, Filtered Rayleigh Scattering

NASA Technical Reports Server (NTRS)

Otugen, M. Volkan; Popovic, Svetozar

1996-01-01

Ongoing research in Rayleigh scattering diagnostics for variable density low speed flow applications and for supersonic flow measurements are described. During the past several years, the focus has been on the development and use of a Nd:YAG-based Rayleigh scattering system with improved signal-to-noise characteristics and with applicability to complex, confined flows. This activity serves other research projects in the Aerodynamics Laboratory which require the non-contact, accurate, time-frozen measurement of gas density, pressure, and temperature (each separately), in a fairly wide dynamic range of each parameter. Recently, with the acquisition of a new seed-injected Nd:YAG laser, effort also has been directed to the development of a high-speed velocity probe based on a spectrally resolved Rayleigh scattering technique.

Influence of shock waves from plasma actuators on transonic and supersonic airflow

NASA Astrophysics Data System (ADS)

Mursenkova, I. V.; Znamenskaya, I. A.; Lutsky, A. E.

2018-03-01

This paper presents experimental and numerical investigations of high-current sliding surface discharges of nanosecond duration and their effect on high-speed flow as plasma actuators in a shock tube. This study deals with the effectiveness of a sliding surface discharge at low and medium air pressure. Results cover the electrical characteristics of the discharge and optical visualization of the discharge and high-speed post-discharge flow. A sliding surface discharge is first studied in quiescent air conditions and then in high-speed flow, being initiated in the boundary layer at a transverse flow velocity of 50-950 m s-1 behind a flat shock wave in air of density 0.04-0.45 kg m-3. The discharge is powered by a pulse voltage of 25-30 kV and the electric current is ~0.5 kA. Shadow imaging and particle image velocimetry (PIV) are used to measure the flow field parameters after the pulse surface discharge. Shadow imaging reveals shock waves originating from the channels of the discharge configurations. PIV is used to measure the velocity field resulting from the discharge in quiescent air and to determine the homogeneity of energy release along the sliding discharge channel. Semicylindrical shock waves from the channels of the sliding discharge have an initial velocity of more than 600 m s-1. The shock-wave configuration floats in the flow along the streamlined surface. Numerical simulation based on the equations of hydrodynamics matched with the experiment showed that 25%-50% of the discharge energy is instantly transformed into heat energy in a high-speed airflow, leading to the formation of shock waves. This energy is comparable to the flow enthalpy and can result in significant modification of the boundary layer and the entire flow.

Experimental and Computational Studies of the Flow Over a Sting Mounted Planetary Probe Configuration

NASA Technical Reports Server (NTRS)

Holden, Michael S.; Harvey, John K.; Boyd, Iain D.; George, Jyothish; Horvath, Thomas J.

1997-01-01

This paper summarizes the results of a series of experimental studies in the LENS shock tunnel and computations with DSMC and Navier Stokes codes which have been made to examine the aerothermal and flowfield characteristics of the flow over a sting-supported planetary probe configuration in hypervelocity air and nitrogen flows. The experimental program was conducted in the LENS hypervelocity shock tunnel at total enthalpies of 5and 10 MJkg for a range of reservoir pressure conditions from 70 to 500 bars. Heat transfer and pressure measurements were made on the front and rear face of the probe and along the supporting sting. High-speed and single shot schlieren photography were also employed to examine the flow over the model and the time to establish the flow in the base recirculation region. Predictions of the flowfield characteristics and the distributions of heat transfer and pressure were made with DSMC codes for rarefied flow conditions and with the Navier-Stokes solvers for the higher pressure conditions where the flows were assumed to be laminar. Analysis of the time history records from the heat transfer and pressure instrumentation on the face of the probe and in the base region indicated that the base flow was fully established in under 4 milliseconds from flow initiation or between 35 and 50 flow lengths based on base height. The measurements made in three different tunnel entries with two models of identical geometries but with different instrumentation packages, one prepared by NASA Langley and the second prepared by CUBRC, demonstrated good agreement between heat transfer measurements made with two different types of thin film and coaxial gage instrumentation. The measurements of heat transfer and pressure to the front face of the probe were in good agreement with theoretical predictions from both the DSMC and Navier Stokes codes. For the measurements made in low density flows, computations with the DSMC code were found to compare well with the pressure and heat transfer measurements on the sting, although the computed heat transfer rates in the recirculation region did not exhibit the same characteristics as the measurements. For the 10MJkg and 500 bar reservoir match point condition, the measurements and heat transfer along the sting from the first group of studies were in agreement with the Navier Stokes solutions for laminar conditions. A similar set of measurements made in later tests where the model was moved to a slightly different position in the test section indicated that the boundary layer in the reattachment compression region was close to transition or transitional where small changes in the test environment can result in larger than laminar heating rates. The maximum heating coefficients on the sting observed in the present studies was a small fraction of similar measurements obtained at nominally the same conditions in the HEG shock tunnel, where it is possible for transition to occur in the base flow, and in the low enthalpy studies conducted in the NASA Langley high Reynolds number Mach 10 tunnel where the base flow was shown to be turbulent. While the hybrid Navier- StokedDMSC calculations by Gochberg et al. (Reference 1) suggested that employing the Navier- Stokes calculations for the entire flowfield could be seriously in error in the base region for the 10 MJkg, 500 bar test case, similar calculations performed by Cornell, presented here, do not.

High resolution mapping of riffle-pool dynamics based on ADCP and close-range remote sensing data

NASA Astrophysics Data System (ADS)

Salmela, Jouni; Kasvi, Elina; Alho, Petteri

2017-04-01

Present development of mobile laser scanning (MLS) and close-range photogrammetry with unmanned aerial vehicle (UAV) enable us to create seamless digital elevation models (DEMs) of the riverine environment. Remote-controlled flow measurement platforms have also improved spatio-temporal resolution of the flow field data. In this study, acoustic Doppler current profiler (ADCP) attached to remote-controlled mini-boat, UAV-based bathymetry and MLS techniques were utilized to create the high-resolution DEMs of the river channel. These high-resolution measurements can be used in many fluvial applications such as computational fluid dynamics, channel change detection, habitat mapping or hydro-electric power plant planning. In this study we aim: 1) to analyze morphological changes of river channel especially riffle and pool formations based on fine-scale DEMs and ADCP measurements, 2) to analyze flow fields and their effect on morphological changes. The interest was mainly focused on reach-scale riffle-pool dynamics within two-year period of 2013 and 2014. The study was performed in sub-arctic meandering Pulmankijoki River located in Northern Finland. The river itself has shallow and clear water and sandy bed sediment. Discharge remains typically below 10 m3s-1 most of the year but during snow melt period in spring the discharge may exceed 70 m3s-1. We compared DEMs and ADCP measurements to understand both magnitude and spatio-temporal change of the river bed. Models were accurate enough to study bed form changes and locations and persistence of riffles and pools. We analyzed their locations with relation to flow during the peak and low discharge. Our demonstrated method has improved significantly spatio-temporal resolution of riverine DEMs compared to other cross-sectional and photogrammetry based models. Together with flow field measurements we gained better understanding of riverbed-water interaction

Rarefied gas electro jet (RGEJ) micro-thruster for space propulsion

NASA Astrophysics Data System (ADS)

Blanco, Ariel; Roy, Subrata

2017-11-01

This article numerically investigates a micro-thruster for small satellites which utilizes plasma actuators to heat and accelerate the flow in a micro-channel with rarefied gas in the slip flow regime. The inlet plenum condition is considered at 1 Torr with flow discharging to near vacuum conditions (<0.05 Torr). The Knudsen numbers at the inlet and exit planes are ~0.01 and ~0.1, respectively. Although several studies have been performed in micro-hallow cathode discharges at constant pressure, to our knowledge, an integrated study of the glow discharge physics and resulting fluid flow of a plasma thruster under these low pressure and low Knudsen number conditions is yet to be reported. Numerical simulations of the charge distribution due to gas ionization processes and the resulting rarefied gas flow are performed using an in-house code. The mass flow rate, thrust, specific impulse, power consumption and the thrust effectiveness of the thruster are predicted based on these results. The ionized gas is modelled using local mean energy approximation. An electrically induced body force and a thermal heating source are calculated based on the space separated charge distribution and the ion Joule heating, respectively. The rarefied gas flow with these electric force and heating source is modelled using density-based compressible flow equations with slip flow boundary conditions. The results show that a significant improvement of specific impulse can be achieved over highly optimized cold gas thrusters using the same propellant.

Physics-Based Modeling and Measurement of High-Flux Condensation Heat Transfer

DTIC Science & Technology

2011-09-01

TRANSFER (Contract No. N000140811139) by Prof. Issam Mudawar Sung-Min Kim Joseph Kim Boiling and Two-Phase Flow Laboratory School of...Final 01-10-2008 to 30-09-2011 Physics-Based Modeling and Measurement of High-Flux Condensation Heat Transfer NA N00014-08-1-1139 NA NA NA NA Mudawar ...respectively. phase change, condensation, electronics cooling, micro-channel, high-flux U U U UU 107 Mudawar , Issam 765-494-5705 Reset PHYSICS-BASED

Counter Clockwise Rotation of Cylinder with Variable Position to Control Base Flows

NASA Astrophysics Data System (ADS)

Asadullah, Mohammed; Khan, S. A.; Asrar, Waqar; Sulaeman, E.

2018-05-01

Experimental study of supersonic base flow at Mach 2 has been carried out to see the effect of cylinder when rotated counter clockwise inside the dead zone at variable locations near its base to control base pressure for different level of expansion for area ratio 9. Active cylinder of 2 mm diameter rotating counter clockwise when seen from top, is mounted as a controller. Three locations are chosen from the side wall of square duct namely at 2, 4, 6 mm respectively and 8 mm from square nozzle exit in the base region to mount the controller. Base pressure in recirculation zone and wall pressure along the square duct length has been measured with and without control. The experiments were carried out for NPR 2, 3, 6, 7.8 and 8.5. Cylinder when rotated counter clockwise as an active controller were found to reduce the base drag as high as 62 percent at NPR 8.5 when located near to duct wall and 50 percent when located away from duct wall for the same NPR. For perfectly expanded flows at NPR 7.8 the reduction in base drag was 53 percent near duct wall and 44 percent near duct wall. The active controller was up to 19 percentage effective for over expanded flows near to duct wall and up to 12 percent when located away from duct wall. Also, the control did not adversely affect the flow field.

Enstrophy-based proper orthogonal decomposition of flow past rotating cylinder at super-critical rotating rate

NASA Astrophysics Data System (ADS)

Sengupta, Tapan K.; Gullapalli, Atchyut

2016-11-01

Spinning cylinder rotating about its axis experiences a transverse force/lift, an account of this basic aerodynamic phenomenon is known as the Robins-Magnus effect in text books. Prandtl studied this flow by an inviscid irrotational model and postulated an upper limit of the lift experienced by the cylinder for a critical rotation rate. This non-dimensional rate is the ratio of oncoming free stream speed and the surface speed due to rotation. Prandtl predicted a maximum lift coefficient as CLmax = 4π for the critical rotation rate of two. In recent times, evidences show the violation of this upper limit, as in the experiments of Tokumaru and Dimotakis ["The lift of a cylinder executing rotary motions in a uniform flow," J. Fluid Mech. 255, 1-10 (1993)] and in the computed solution in Sengupta et al. ["Temporal flow instability for Magnus-robins effect at high rotation rates," J. Fluids Struct. 17, 941-953 (2003)]. In the latter reference, this was explained as the temporal instability affecting the flow at higher Reynolds number and rotation rates (>2). Here, we analyze the flow past a rotating cylinder at a super-critical rotation rate (=2.5) by the enstrophy-based proper orthogonal decomposition (POD) of direct simulation results. POD identifies the most energetic modes and helps flow field reconstruction by reduced number of modes. One of the motivations for the present study is to explain the shedding of puffs of vortices at low Reynolds number (Re = 60), for the high rotation rate, due to an instability originating in the vicinity of the cylinder, using the computed Navier-Stokes equation (NSE) from t = 0 to t = 300 following an impulsive start. This instability is also explained through the disturbance mechanical energy equation, which has been established earlier in Sengupta et al. ["Temporal flow instability for Magnus-robins effect at high rotation rates," J. Fluids Struct. 17, 941-953 (2003)].

The Burgers/squirt-flow seismic model of the crust and mantle

NASA Astrophysics Data System (ADS)

Carcione, José M.; Poletto, Flavio; Farina, Biancamaria

2018-01-01

Part of the crust shows generally brittle behaviour while areas of high temperature and/or high pore pressure, including the mantle, may present ductile behaviour. For instance, the potential heat source of geothermal fields, overpressured formations and molten rocks. Seismic waves can be used to detect these conditions on the basis of reflection and transmission events. Basically, from the elastic-plastic point of view the seismic properties (seismic velocity, quality factor and density) depend on effective pressure and temperature. Confining and pore pressures have opposite effects on these properties, and high temperatures may induce a similar behaviour by partial melting. In order to model these effects, we consider a poro-viscoelastic model based on the Burgers mechanical element and the squirt-flow model to represent the properties of the rock frame to describe ductility in which deformation takes place by shear plastic flow, and to model local and global fluid flow effects. The Burgers element allows us to model the effects of the steady-state creep flow on the dry-rock frame. The stiffness components of the brittle and ductile media depend on stress and temperature through the shear viscosity, which is obtained by the Arrhenius equation and the octahedral stress criterion. Effective pressure effects are taken into account in the dry-rock moduli by using exponential functions whose parameters are obtained by fitting experimental data as a function of confining pressure. Since fluid effects are important, the density and bulk modulus of the saturating fluids (water at sub- and supercritical conditions) are modeled by using the equations provided by the NIST website. The squirt-flow model has a single free parameter represented by the aspect ratio of the grain contacts. The theory generalizes a preceding theory based on Gassmann (low-frequency) moduli to the more general case of the presence of local (squirt) flow and global (Biot) flow, which contribute with additional attenuation mechanisms to the wave propagation.

Calculation and measurement of a neutral air flow velocity impacting a high voltage capacitor with asymmetrical electrodes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Malík, M., E-mail: michal.malik@tul.cz; Primas, J.; Kopecký, V.

2014-01-15

This paper deals with the effects surrounding phenomenon of a mechanical force generated on a high voltage asymmetrical capacitor (the so called Biefeld-Brown effect). A method to measure this force is described and a formula to calculate its value is also given. Based on this the authors derive a formula characterising the neutral air flow velocity impacting an asymmetrical capacitor connected to high voltage. This air flow under normal circumstances lessens the generated force. In the following part this velocity is measured using Particle Image Velocimetry measuring technique and the results of the theoretically calculated velocity and the experimentally measuredmore » value are compared. The authors found a good agreement between the results of both approaches.« less

Advanced lattice Boltzmann scheme for high-Reynolds-number magneto-hydrodynamic flows

NASA Astrophysics Data System (ADS)

De Rosis, Alessandro; Lévêque, Emmanuel; Chahine, Robert

2018-06-01

Is the lattice Boltzmann method suitable to investigate numerically high-Reynolds-number magneto-hydrodynamic (MHD) flows? It is shown that a standard approach based on the Bhatnagar-Gross-Krook (BGK) collision operator rapidly yields unstable simulations as the Reynolds number increases. In order to circumvent this limitation, it is here suggested to address the collision procedure in the space of central moments for the fluid dynamics. Therefore, an hybrid lattice Boltzmann scheme is introduced, which couples a central-moment scheme for the velocity with a BGK scheme for the space-and-time evolution of the magnetic field. This method outperforms the standard approach in terms of stability, allowing us to simulate high-Reynolds-number MHD flows with non-unitary Prandtl number while maintaining accuracy and physical consistency.

Periodicity and Multi-scale Analysis of Runoff and Sediment Load in the Wulanghe River, Jinsha River

NASA Astrophysics Data System (ADS)

Chen, Yiming

2018-01-01

Based on the annual runoff and sediment data (1959-2014 ) of Zongguantian hydrological station, time-frequency wavelet transform characteristics and their periodic rules of high and low flow alternating change were analyzed in multi-time scales by the Morlet continue wavelet transformation (CWT). It is concluded that the primary periods of runoff and sediment load time series of the high and low annual flow in the different time scales were 12-year, 3-year and 26-year, 18-year, 13-year, 5-year, respectively, and predicted that the major variant trend of the two time series would been gradually decreasing and been in the high flow period around 8-year (from 2014 to 2022) and 10-year (from 2014 to 2020).

Construction of Low Dissipative High Order Well-Balanced Filter Schemes for Non-Equilibrium Flows

NASA Technical Reports Server (NTRS)

Wang, Wei; Yee, H. C.; Sjogreen, Bjorn; Magin, Thierry; Shu, Chi-Wang

2009-01-01

The goal of this paper is to generalize the well-balanced approach for non-equilibrium flow studied by Wang et al. [26] to a class of low dissipative high order shock-capturing filter schemes and to explore more advantages of well-balanced schemes in reacting flows. The class of filter schemes developed by Yee et al. [30], Sjoegreen & Yee [24] and Yee & Sjoegreen [35] consist of two steps, a full time step of spatially high order non-dissipative base scheme and an adaptive nonlinear filter containing shock-capturing dissipation. A good property of the filter scheme is that the base scheme and the filter are stand alone modules in designing. Therefore, the idea of designing a well-balanced filter scheme is straightforward, i.e., choosing a well-balanced base scheme with a well-balanced filter (both with high order). A typical class of these schemes shown in this paper is the high order central difference schemes/predictor-corrector (PC) schemes with a high order well-balanced WENO filter. The new filter scheme with the well-balanced property will gather the features of both filter methods and well-balanced properties: it can preserve certain steady state solutions exactly; it is able to capture small perturbations, e.g., turbulence fluctuations; it adaptively controls numerical dissipation. Thus it shows high accuracy, efficiency and stability in shock/turbulence interactions. Numerical examples containing 1D and 2D smooth problems, 1D stationary contact discontinuity problem and 1D turbulence/shock interactions are included to verify the improved accuracy, in addition to the well-balanced behavior.

A hard-soft microfluidic-based biosensor flow cell for SPR imaging application.

PubMed

Liu, Changchun; Cui, Dafu; Li, Hui

2010-09-15

An ideal microfluidic-based biosensor flow cell should have not only a "soft" interface for high strength sealing with biosensing chips, but also "hard" macro-to-micro interface for tubing connection. Since these properties are exclusive of each other, no one material can provide the advantages of both. In this paper, we explore the application of a SiO(2) thin film, deposited by plasma-enhanced chemical vapor deposition (PECVD) technology, as an intermediate layer for irreversibly adhering polydimethylsiloxane (PDMS) to plastic substrate, and develop a hard-soft, compact, robust microfluidic-based biosensor flow cell for the multi-array immunoassay application of surface plasmon resonance (SPR) imaging. This hard-soft biosensor flow cell consists of one rigid, computer numerically controlled (CNC)-machined poly(methyl methacrylate) (PMMA) base coated with a 200 nm thick SiO(2) thin film, and one soft PDMS microfluidic layer. This novel microfluidic-based biosensor flow cell does not only keep the original advantage of conventional PDMS-based biosensor flow cell such as the intrinsically soft interface, easy-to-fabrication, and low cost, but also has a rigid, robust, easy-to-use interface to tubing connection and can be operated up to 185 kPa in aqueous environments without failure. Its application was successfully demonstrated with two types of experiments by coupling with SPR imaging biosensor: the real-time monitoring of the immunoglobulin G (IgG) interaction, as well as the detection of sulfamethoxazole (SMOZ) and sulfamethazine (SMZ) with the sensitivity of 3.5 and 0.6 ng/mL, respectively. This novel hard-soft microfluidic device is also useful for a variety of other biosensor flow cells. Copyright 2010 Elsevier B.V. All rights reserved.

Comprehensive theory of the Deans' switch as a variable flow splitter: fluid mechanics, mass balance, and system behavior.

PubMed

Boeker, Peter; Leppert, Jan; Mysliwietz, Bodo; Lammers, Peter Schulze

2013-10-01

The Deans' switch is an effluent switching device based on controlling flows of carrier gas instead of mechanical valves in the analytical flow path. This technique offers high inertness and a wear-free operation. Recently new monolithic microfluidic devices have become available. In these devices the whole flow system is integrated into a small metal device with low thermal mass and leak-tight connections. In contrast to a mechanical valve-based system, a flow-controlled system is more difficult to calculate. Usually the Deans' switch is used to switch one inlet to one of two outlets, by means of two auxiliary flows. However, the Deans' switch can also be used to deliver the GC effluent with a specific split ratio to both outlets. The calculation of the split ratio of the inlet flow to the two outlets is challenging because of the asymmetries of the flow resistances. This is especially the case, if one of the outlets is a vacuum device, such as a mass spectrometer, and the other an atmospheric detector, e.g. a flame ionization detector (FID) or an olfactory (sniffing) port. The capillary flows in gas chromatography are calculated with the Hagen-Poiseuille equation of the laminar, isothermal and compressible flow in circular tubes. The flow resistances in the new microfluidic devices have to be calculated with the corresponding equation for rectangular cross-section microchannels. The Hagen-Poiseuille equation underestimates the flow to a vacuum outlet. A corrected equation originating from the theory of rarefied flows is presented. The calculation of pressures and flows of a Deans' switch based chromatographic system is done by the solution of mass balances. A specific challenge is the consideration of the antidiffusion resistor between the two auxiliary gas lines of the Deans' switch. A full solution for the calculation of the Deans' switch including this restrictor is presented. Results from validation measurements are in good accordance with the developed theories. A spreadsheet-based flow calculator is part of the Supporting Information.

A symmetric organic-based nonaqueous redox flow battery and its state of charge diagnostics by FTIR

DOE PAGES

Duan, Wentao; Vemuri, Rama Ses; Milshtein, Jarrod D.; ...

2016-03-10

Redox flow batteries have shown outstanding promise for grid-scale energy storage to promote utilization of renewable energy and improve grid stability. Nonaqueous battery systems can potentially achieve high energy density because of their broad voltage window. In this paper, we report a new organic redox-active material for use in a nonaqueous redox flow battery, 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (PTIO) that has high solubility (>2.6 M) in organic solvents. PTIO exhibits electrochemically reversible disproportionation reactions and thus can serve as both anolyte and catholyte redox materials in a symmetric flow cell. The PTIO flow battery has a moderate cell voltage of ~1.7 V andmore » shows good cyclability under both cyclic voltammetry and flow cell conditions. Moreover, we demonstrate that FTIR can offer accurate estimation of the PTIO concentration in electrolytes and determine the state of charge of the PTIO flow cell, which suggests FTIR potentially as a powerful online battery status sensor. In conclusion, this study is expected to inspire more insights in this under-addressed area of state of charge analysis aiming at operational safety and reliability of flow batteries.« less

Determining the effects of dams on subdaily variation in river flows at a whole-basin scale

USGS Publications Warehouse

Zimmerman, J.K.H.; Letcher, B.H.; Nislow, K.H.; Lutz, K.A.; Magilligan, F.J.

2010-01-01

River regulation can alter the frequency and magnitude of subdaily flow variations causing major impacts on ecological structure and function. We developed an approach to quantify subdaily flow variation for multiple sites across a large watershed to assess the potential impacts of different dam operations (flood control, run-of-river hydropower and peaking hydropower) on natural communities. We used hourly flow data over a 9-year period from 30 stream gages throughout the Connecticut River basin to calculate four metrics of subdaily flow variation and to compare sites downstream of dams with unregulated sites. Our objectives were to (1) determine the temporal scale of data needed to characterize subdaily variability; (2) compare the frequency of days with high subdaily flow variation downstream of dams and unregulated sites; (3) analyse the magnitude of subdaily variation at all sites and (4) identify individual sites that had subdaily variation significantly higher than unregulated locations. We found that estimates of flow variability based on daily mean flow data were not sufficient to characterize subdaily flow patterns. Alteration of subdaily flows was evident in the number of days natural ranges of variability were exceeded, rather than in the magnitude of subdaily variation, suggesting that all rivers may exhibit highly variable subdaily flows, but altered rivers exhibit this variability more frequently. Peaking hydropower facilities had the most highly altered subdaily flows; however, we observed significantly altered ranges of subdaily variability downstream of some flood-control and run-of-river hydropower dams. Our analysis can be used to identify situations where dam operating procedures could be modified to reduce the level of hydrologic alteration. ?? 2009 John Wiley & Sons, Ltd.

Hydrological classification of natural flow regimes to support environmental flow assessments in intensively regulated Mediterranean rivers, Segura River Basin (Spain).

PubMed

Belmar, Oscar; Velasco, Josefa; Martinez-Capel, Francisco

2011-05-01

Hydrological classification constitutes the first step of a new holistic framework for developing regional environmental flow criteria: the "Ecological Limits of Hydrologic Alteration (ELOHA)". The aim of this study was to develop a classification for 390 stream sections of the Segura River Basin based on 73 hydrological indices that characterize their natural flow regimes. The hydrological indices were calculated with 25 years of natural monthly flows (1980/81-2005/06) derived from a rainfall-runoff model developed by the Spanish Ministry of Environment and Public Works. These indices included, at a monthly or annual basis, measures of duration of droughts and central tendency and dispersion of flow magnitude (average, low and high flow conditions). Principal Component Analysis (PCA) indicated high redundancy among most hydrological indices, as well as two gradients: flow magnitude for mainstream rivers and temporal variability for tributary streams. A classification with eight flow-regime classes was chosen as the most easily interpretable in the Segura River Basin, which was supported by ANOSIM analyses. These classes can be simplified in 4 broader groups, with different seasonal discharge pattern: large rivers, perennial stable streams, perennial seasonal streams and intermittent and ephemeral streams. They showed a high degree of spatial cohesion, following a gradient associated with climatic aridity from NW to SE, and were well defined in terms of the fundamental variables in Mediterranean streams: magnitude and temporal variability of flows. Therefore, this classification is a fundamental tool to support water management and planning in the Segura River Basin. Future research will allow us to study the flow alteration-ecological response relationship for each river type, and set the basis to design scientifically credible environmental flows following the ELOHA framework.

A Protocol for Electrochemical Evaluations and State of Charge Diagnostics of a Symmetric Organic Redox Flow Battery

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duan, Wentao; Vemuri, Rama S.; Hu, Dehong

Redox flow batteries have been considered as one of the most promising stationary energy storage solutions for improving the reliability of the power grid and deployment of renewable energy technologies. Among the many flow battery chemistries, nonaqueous flow batteries have the potential to achieve high energy density because of the broad voltage windows of nonaqueous electrolytes. However, significant technical hurdles exist currently limiting nonaqueous flow batteries to demonstrate their full potential, such as low redox concentrations, low operating currents, under-explored battery status monitoring, etc. In an attempt to address these limitations, we report a nonaqueous flow battery based on amore » highly soluble, redox-active organic nitronyl nitroxide radical compound, 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide (PTIO). This redox materials exhibits an ambipolar electrochemical property with two reversible redox pairs that are moderately separated by a voltage gap of ~1.7 V. Therefore, PTIO can serve as both anolyte and catholyte redox materials to form a symmetric flow battery chemistry, which affords the advantages such as high effective redox concentrations and low irreversible redox material crossover. The PTIO flow battery shows decent electrochemical cyclability under cyclic voltammetry and flow cell conditions; an improved redox concentration of 0.5 M PTIO and operational current density of 20 mA cm-2 were achieved in flow cell tests. Moreover, we show that Fourier transform infrared (FTIR) spectroscopy could measure the PTIO concentrations during the PTIO flow battery cycling and offer reasonably accurate detection of the battery state of charge (SOC) as cross-validated by electron spin resonance measurements. This study suggests FTIR can be used as a reliable online SOC sensor to monitor flow battery status and ensure battery operations stringently in a safe SOC range.« less

Ducted fan inlet/exit and rotor tip flow improvements for vertical lift systems

NASA Astrophysics Data System (ADS)

Akturk, Ali

The current research utilized experimental and computational techniques in 5" and 22" diameter ducted fan test systems that have been custom designed and manufactured. Qualitative investigation of flow around the ducted fan was also performed using smoke flow visualizations. Quantitative measurements consisted of 2D and 3D velocity measurements using planar and Stereoscopic Particle Image Velocimetry (PIV and SPIV), high resolution total pressure measurements using Kiel total pressure probes and real time six-component force and torque measurements. The computational techniques used in this thesis included a recently developed radial equilibrium based rotor model(REBRM) and a three dimensional Reynolds-Averaged Navier Stokes (RANS) based CFD model. A radial equilibrium based rotor model (REBRM) developed by the author was effectively integrated into a three-dimensional RANS based computational system. The PIV measurements and computational flow predictions using (REBRM) near the fan inlet plane were in a good agreement at hover and forward flight conditions. The aerodynamic modifications resulting from the fan inlet flow distortions in forward flight regime were clearly captured in 2D PIV results. High resolution total pressure measurements at the downstream of the fan rotor showed that tip leakage, rotor hub separation, and passage flow related total pressure losses were dominant in hover condition. However, the losses were dramatically increased in forward flight because of inlet lip separation and distortion. A novel ducted fan inlet flow conditioning concept named "Double Ducted Fan" (DDF) was developed. The (DDF) concept has a potential to significantly improve the performance and controllability of VTOL UAVs and many other ducted fan based vertical lift systems. The new concept that will significantly reduce the inlet lip separation related performance penalties used a secondary stationary duct system to control "inlet lip separation" occurring especially at elevated forward flight velocities. The (DDF) is self-adjusting in a wide forward flight velocity range. DDFs corrective aerodynamic in influence becomes more pronounced with increasing flight velocity due to its inherent design properties. RANS simulations of the flow around rotor blades and duct geometry in the rotating frame of reference provided a comprehensive description of the tip leakage and passage flow in the flow environment of the two ducted fan research facilities developed throughout this thesis. The aerodynamic measurements and results of the RANS simulation showed good agreement especially near the tip region. A number of novel tip treatments based on custom designed pressure side extensions were introduced. Various tip leakage mitigation schemes were introduced by varying the chordwise location and the width of the extension in the circumferential direction. The current study showed that a proper selection of the pressure side bump location and width were the two critical parameters in influencing the success of the tip leakage mitigation approach. Significant gains in axial mean velocity component were observed when a proper pressure side tip extension was used. It is also observed that an effective tip leakage mitigation scheme significantly reduced the tangential velocity component near the tip of the axial fan blade. Reduced tip clearance related flow interactions were essential in improving the energy efficiency and range of ducted fan based vehicle. Full and inclined pressure side tip squealers were designed. Squealer tips were effective in changing the overall trajectory of the tip vortex to a higher path in radial direction. The interaction of rotor blades and tip vortex was effectively reduced and aerodynamic performance of the rotor blades was improved. The overall aerodynamic gain was a measurable reduction in leakage mass flow rate. This leakage reduction increased thrust significantly. Full and inclined pressure side tip squealers increased thrust obtained in hover condition by 9.1 % and 9.6 % respectively. A reduction or elimination of the momentum deficit in tip vortices is essential to reduce the adverse performance effects originating from the unsteady and highly turbulent tip leakage flows rotating against a stationary casing. The novel tip treatments developed throughout this thesis research are highly effective in reducing the adverse performance effects of ducted fan systems developed for VTOL vehicles. (Abstract shortened by UMI.)

Analysis of Flowfields over Four-Engine DC-X Rockets

NASA Technical Reports Server (NTRS)

Wang, Ten-See; Cornelison, Joni

1996-01-01

The objective of this study is to validate a computational methodology for the aerodynamic performance of an advanced conical launch vehicle configuration. The computational methodology is based on a three-dimensional, viscous flow, pressure-based computational fluid dynamics formulation. Both wind-tunnel and ascent flight-test data are used for validation. Emphasis is placed on multiple-engine power-on effects. Computational characterization of the base drag in the critical subsonic regime is the focus of the validation effort; until recently, almost no multiple-engine data existed for a conical launch vehicle configuration. Parametric studies using high-order difference schemes are performed for the cold-flow tests, whereas grid studies are conducted for the flight tests. The computed vehicle axial force coefficients, forebody, aftbody, and base surface pressures compare favorably with those of tests. The results demonstrate that with adequate grid density and proper distribution, a high-order difference scheme, finite rate afterburning kinetics to model the plume chemistry, and a suitable turbulence model to describe separated flows, plume/air mixing, and boundary layers, computational fluid dynamics is a tool that can be used to predict the low-speed aerodynamic performance for rocket design and operations.

Numerical simulation of liquid droplet breakup in supersonic flows

NASA Astrophysics Data System (ADS)

Liu, Nan; Wang, Zhenguo; Sun, Mingbo; Wang, Hongbo; Wang, Bing

2018-04-01

A five-equation model based on finite-difference frame was utilized to simulate liquid droplet breakup in supersonic flows. To enhance the interface-capturing quality, an anti-diffusion method was introduced as a correction of volume-fraction after each step of calculation to sharpen the interface. The robustness was guaranteed by the hybrid variable reconstruction in which the second-order and high-order method were respectively employed in discontinuous and continuous flow fields. According to the recent classification of droplet breakup regimes, the simulations lay in the shear induced entrainment regime. Comparing to the momentum of the high-speed air flows, surface tension and viscid force were negligible in both two-dimensional and three-dimensional simulations. The inflow conditions were set as Mach 1.2, 1.5 and 1.8 to reach different dynamic pressure with the liquid to gas density ratio being 1000 initially. According to the results of simulations, the breakup process was divided into three stages which were analyzed in details with the consideration of interactions between gas and liquid. The shear between the high-speed gas flow and the liquid droplet was found to be the sources of surface instabilities on windward, while the instabilities on the leeward side were originated by vortices. Movement of the liquid mass center was studied, and the unsteady acceleration was observed. In addition, the characteristic breakup time was around 1.0 based on the criterion of either droplet thickness or liquid volume fraction.

A high sensitivity fiber optic macro-bend based gas flow rate transducer for low flow rates: Theory, working principle, and static calibration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schena, Emiliano; Saccomandi, Paola; Silvestri, Sergio

2013-02-15

A novel fiber optic macro-bend based gas flowmeter for low flow rates is presented. Theoretical analysis of the sensor working principle, design, and static calibration were performed. The measuring system consists of: an optical fiber, a light emitting diode (LED), a Quadrant position sensitive Detector (QD), and an analog electronic circuit for signal processing. The fiber tip undergoes a deflection in the flow, acting like a cantilever. The consequent displacement of light spot center is monitored by the QD generating four unbalanced photocurrents which are function of fiber tip position. The analog electronic circuit processes the photocurrents providing voltage signalmore » proportional to light spot position. A circular target was placed on the fiber in order to increase the sensing surface. Sensor, tested in the measurement range up to 10 l min{sup -1}, shows a discrimination threshold of 2 l min{sup -1}, extremely low fluid dynamic resistance (0.17 Pa min l{sup -1}), and high sensitivity, also at low flow rates (i.e., 33 mV min l{sup -1} up to 4 l min{sup -1} and 98 mV min l{sup -1} from 4 l min{sup -1} up to 10 l min{sup -1}). Experimental results agree with the theoretical predictions. The high sensitivity, along with the reduced dimension and negligible pressure drop, makes the proposed transducer suitable for medical applications in neonatal ventilation.« less

A Novel Uncertainty Framework for Improving Discharge Data Quality Using Hydraulic Modelling.

NASA Astrophysics Data System (ADS)

Mansanarez, V.; Westerberg, I.; Lyon, S. W.; Lam, N.

2017-12-01

Flood risk assessments rely on accurate discharge data records. Establishing a reliable stage-discharge (SD) rating curve for calculating discharge from stage at a gauging station normally takes years of data collection efforts. Estimation of high flows is particularly difficult as high flows occur rarely and are often practically difficult to gauge. Hydraulically-modelled rating curves can be derived based on as few as two concurrent stage-discharge and water-surface slope measurements at different flow conditions. This means that a reliable rating curve can, potentially, be derived much faster than a traditional rating curve based on numerous stage-discharge gaugings. We introduce an uncertainty framework using hydraulic modelling for developing SD rating curves and estimating their uncertainties. The proposed framework incorporates information from both the hydraulic configuration (bed slope, roughness, vegetation) and the information available in the stage-discharge observation data (gaugings). This method provides a direct estimation of the hydraulic configuration (slope, bed roughness and vegetation roughness). Discharge time series are estimated propagating stage records through posterior rating curve results.We applied this novel method to two Swedish hydrometric stations, accounting for uncertainties in the gaugings for the hydraulic model. Results from these applications were compared to discharge measurements and official discharge estimations.Sensitivity analysis was performed. We focused analyses on high-flow uncertainty and the factors that could reduce this uncertainty. In particular, we investigated which data uncertainties were most important, and at what flow conditions the gaugings should preferably be taken.

Artificial sensory hairs based on the flow sensitive receptor hairs of crickets

NASA Astrophysics Data System (ADS)

Dijkstra, M.; van Baar, J. J.; Wiegerink, R. J.; Lammerink, T. S. J.; de Boer, J. H.; Krijnen, G. J. M.

2005-07-01

This paper presents the modelling, design, fabrication and characterization of flow sensors based on the wind-receptor hairs of crickets. Cricket sensory hairs are highly sensitive to drag-forces exerted on the hair shaft. Artificial sensory hairs have been realized in SU-8 on suspended SixNy membranes. The movement of the membranes is detected capacitively. Capacitance versus voltage, frequency dependence and directional sensitivity measurements have been successfully carried out on fabricated sensor arrays, showing the viability of the concept.

Perfect gas effects in compressible rapid distortion theory

NASA Technical Reports Server (NTRS)

Kerschen, E. J.; Myers, M. R.

1987-01-01

The governing equations presented for small amplitude unsteady disturbances imposed on steady, compressible mean flows that are two-dimensional and nearly uniform have their basis in the perfect gas equations of state, and therefore generalize previous results based on tangent gas theory. While these equations are more complex, this complexity is required for adequate treatment of high frequency disturbances, especially when the base flow Mach number is large; under such circumstances, the simplifying assumptions of tangent gas theory are not applicable.

Continuous inertial microparticle and blood cell separation in straight channels with local microstructures.

PubMed

Wu, Zhenlong; Chen, Yu; Wang, Moran; Chung, Aram J

2016-02-07

Fluid inertia which has conventionally been neglected in microfluidics has been gaining much attention for particle and cell manipulation because inertia-based methods inherently provide simple, passive, precise and high-throughput characteristics. Particularly, the inertial approach has been applied to blood separation for various biomedical research studies mainly using spiral microchannels. For higher throughput, parallelization is essential; however, it is difficult to realize using spiral channels because of their large two dimensional layouts. In this work, we present a novel inertial platform for continuous sheathless particle and blood cell separation in straight microchannels containing microstructures. Microstructures within straight channels exert secondary flows to manipulate particle positions similar to Dean flow in curved channels but with higher controllability. Through a balance between inertial lift force and microstructure-induced secondary flow, we deterministically position microspheres and cells based on their sizes to be separated downstream. Using our inertial platform, we successfully sorted microparticles and fractionized blood cells with high separation efficiencies, high purities and high throughputs. The inertial separation platform developed here can be operated to process diluted blood with a throughput of 10.8 mL min(-1)via radially arrayed single channels with one inlet and two rings of outlets.

Noninvasive and label-free detection of circulating melanoma cells by in vivo photoacoustic flow cytometry

NASA Astrophysics Data System (ADS)

Yang, Ping; Liu, Rongrong; Niu, Zhenyu; Suo, Yuanzhen; He, Hao; Wei, Xunbin

2015-03-01

Melanoma is a malignant tumor of melanocytes. Circulating melanoma cell has high light absorption due to melanin highly contained in melanoma cells. This property is employed for the detection of circulating melanoma cell by in vivo photoacoustic flow cytometry (PAFC). PAFC is based on photoacoustic effect. Compared to in vivo flow cytometry based on fluorescence, PAFC can employ high melanin content of melanoma cells as endogenous biomarkers to detect circulating melanoma cells in vivo. In our research, we developed in vitro experiments to prove the ability of PAFC system of detecting PA signals from melanoma cells. For in vivo experiments, we constructed a model of melanoma tumor bearing mice by inoculating highly metastatic murine melanoma cancer cells B16F10 with subcutaneous injection. PA signals were detected in the blood vessels of mouse ears in vivo. By counting circulating melanoma cells termly, we obtained the number variation of circulating melanoma cells as melanoma metastasized. Those results show that PAFC is a noninvasive and label-free method to detect melanoma metastases in blood or lymph circulation. Our PAFC system is an efficient tool to monitor melanoma metastases, cancer recurrence and therapeutic efficacy.

Enabling high-rate electrochemical flow capacitors based on mesoporous carbon microspheres suspension electrodes

NASA Astrophysics Data System (ADS)

Tian, Meng; Sun, Yueqing; Zhang, Chuanfang (John); Wang, Jitong; Qiao, Wenming; Ling, Licheng; Long, Donghui

2017-10-01

Electrochemical flow capacitor (EFC) is a promising technology for grid energy storage, which combines the fast charging/discharging capability of supercapacitors with the scalable energy capacity of flow batteries. In this study, we report a high-power-density EFC using mesoporous carbon microspheres (MCMs) as suspension electrodes. By using a simple yet effective spray-drying technique, monodispersed MCMs with average particle size of 5 μm, high BET surface area of 1150-1267 m2 g-1, large pore volume of 2-4 cm3 g-1 and controllable mesopore size of 7-30 nm have been successfully prepared. The resultant MCMs suspension electrode shows excellent stability and considerable high capacitance of 100 F g-1 and good cycling ability (86% of initial capacitance after 10000 cycles). Specially, the suspension electrode exhibits excellent rate performance with 75% capacitance retention from 2 to 100 mV s-1, significantly higher than that of microporous carbon electrodes (20∼30%), due to the developed mesoporous channels facilitating for rapid ion diffusion. In addition, the electrochemical responses on both negative and positive suspension electrodes are studied, based on which an optimal capacitance matching between them is suggested for large-scale EFC unit.

High-resolution CFD detects high-frequency velocity fluctuations in bifurcation, but not sidewall, aneurysms.

PubMed

Valen-Sendstad, Kristian; Mardal, Kent-André; Steinman, David A

2013-01-18

High-frequency flow fluctuations in intracranial aneurysms have previously been reported in vitro and in vivo. On the other hand, the vast majority of image-based computational fluid dynamics (CFD) studies of cerebral aneurysms report periodic, laminar flow. We have previously demonstrated that transitional flow, consistent with in vivo reports, can occur in a middle cerebral artery (MCA) bifurcation aneurysm when ultra-high-resolution direct numerical simulation methods are applied. The object of the present study was to investigate if such high-frequency flow fluctuations might be more widespread in adequately-resolved CFD models. A sample of N=12 anatomically realistic MCA aneurysms (five unruptured, seven ruptured), was digitally segmented from CT angiograms. Four were classified as sidewall aneurysms, the other eight as bifurcation aneurysms. Transient CFD simulations were carried out assuming a steady inflow velocity of 0.5m/s, corresponding to typical peak systolic conditions at the MCA. To allow for detection of clinically-reported high-frequency flow fluctuations and resulting flow structures, temporal and spatial resolutions of the CFD simulations were in the order of 0.1 ms and 0.1 mm, respectively. A transient flow response to the stationary inflow conditions was found in five of the 12 aneurysms, with energetic fluctuations up to 100 Hz, and in one case up to 900 Hz. Incidentally, all five were ruptured bifurcation aneurysms, whereas all four sidewall aneurysms, including one ruptured case, quickly reached a stable, steady state solution. Energetic, rapid fluctuations may be overlooked in CFD models of bifurcation aneurysms unless adequate temporal and spatial resolutions are used. Such fluctuations may be relevant to the mechanobiology of aneurysm rupture, and to a recently reported dichotomy between predictors of rupture likelihood for bifurcation vs. sidewall aneurysms. Copyright © 2012 Elsevier Ltd. All rights reserved.

The influence of channel bed disturbance on benthic Chlorophyll a: A high resolution perspective

NASA Astrophysics Data System (ADS)

Katz, Scott B.; Segura, Catalina; Warren, Dana R.

2018-03-01

This study explores how spatial dynamics and frequency of bed mobility events in a headwater stream affect the spatial and temporal variability in stream benthic algal abundance and ultimately the resilience of benthic algae to stream scouring events of different magnitudes. We characterized spatial variability in sediment transport for nine separate flow events (0.1-1.7 of bankfull flow), coupling high resolution (< 0.1 m2) two-dimensional shear stress values with detailed measurements of the channel substrate. The stream bed was categorized into regions of high and low disturbance based on potential mobility of different grain sizes. High resolution (< 0.25 m2), in situ measurements of benthic Chlorophyll-a concentrations (Chl-a) were taken on 18 sampling dates before and after high flow events in regions of the streambed with contrasting disturbance to understand how benthic algal communities respond to sediment transport disturbance through space and time. According to the modeling results, the percentage of the channel likely to be disturbed varied greatly across the different flows and considered grain sizes between 7.7 and 70.4% for the lowest and highest flow events respectively. Mean shear stress in the channel bed across all sampling dates explained 49% of the variance in Chl-a. Over the 18 sampling dates - encompassing post-disturbance impacts and subsequent recovery - Chl-a differed between disturbance level categories defined based on the relative movement of the median grain size on 14 occasions. However, low disturbance locations were not always associated with higher Chl-a. The algal Chl-a biomass at any given time was a function of the stage of algal recovery following a high flow event and the magnitude of the disturbance itself - impacting algal loss during the event. Resistance of the algal communities to bed disturbance and resilience to recovery following a flow event varied spatially. Areas with low shear stress were less susceptible to scour during moderate disturbance events but were slower to recover when scour occurred. In contrast, high shear stress areas responded rapidly to flood events with rapid declines, but also recovered more quickly and appeared to have high potential for maximum accrual within our study reach. Ultimately, timing along with the inverse relationship between resiliency and disturbance frequency highlights the complexity of these processes and the importance of studying the interactions between geomorphic and ecological processes with high resolution across spatial and temporal scales.

Space-based laser-driven MHD generator: Feasibility study

NASA Technical Reports Server (NTRS)

Choi, S. H.

1986-01-01

The feasibility of a laser-driven MHD generator, as a candidate receiver for a space-based laser power transmission system, was investigated. On the basis of reasonable parameters obtained in the literature, a model of the laser-driven MHD generator was developed with the assumptions of a steady, turbulent, two-dimensional flow. These assumptions were based on the continuous and steady generation of plasmas by the exposure of the continuous wave laser beam thus inducing a steady back pressure that enables the medium to flow steadily. The model considered here took the turbulent nature of plasmas into account in the two-dimensional geometry of the generator. For these conditions with the plasma parameters defining the thermal conductivity, viscosity, electrical conductivity for the plasma flow, a generator efficiency of 53.3% was calculated. If turbulent effects and nonequilibrium ionization are taken into account, the efficiency is 43.2%. The study shows that the laser-driven MHD system has potential as a laser power receiver for space applications because of its high energy conversion efficiency, high energy density and relatively simple mechanism as compared to other energy conversion cycles.

Studies on unsaturated flow in dual-scale fiber fabrics

NASA Astrophysics Data System (ADS)

Yan, Fei; Yan, Shilin; Li, Yongjing

2018-03-01

Fiber fabrics in liquid composite molding (LCM) can be recognized as a dual-scale structure. As sink theory developed, this unsaturated flow behavior has already been simulated successfully; however, most of simulated results based on a unit cell under ideal status, thus making results were not agreement with experiment. In this study, an experimental method to establish sink function was proposed. After compared the simulation results by this sink function, it shows high accuracy with the experimental data. Subsequently, the key influencing factors for unsaturated flow have been further investigated; results show that the filling time for unsaturated flow was much longer than saturated flow. In addition, the injection pressure and permeability were the key factors lead to unsaturated flow.

Smart catheter flow sensor for real-time continuous regional cerebral blood flow monitoring

NASA Astrophysics Data System (ADS)

Li, Chunyan; Wu, Pei-Ming; Hartings, Jed A.; Wu, Zhizhen; Ahn, Chong H.; LeDoux, David; Shutter, Lori A.; Narayan, Raj K.

2011-12-01

We present a smart catheter flow sensor for real-time, continuous, and quantitative measurement of regional cerebral blood flow using in situ temperature and thermal conductivity compensation. The flow sensor operates in a constant-temperature mode and employs a periodic heating and cooling technique. This approach ensures zero drift and provides highly reliable data with microelectromechanical system-based thin film sensors. The developed flow sensor has a sensitivity of 0.973 mV/ml/100 g/min in the range from 0 to 160 ml/100 g/min with a linear correlation coefficient of R2 = 0.9953. It achieves a resolution of 0.25 ml/100 g/min and an accuracy better than 5 ml/100 g/min.

Isolation and Applications of Prostate Side Population Cells Based on Dye Cycle Violet Efflux

PubMed Central

Gangavarapu, Kalyan J.; Huss, Wendy J.

2011-01-01

This unit describes methods for the digestion of human prostate clinical specimens, dye cycle violet (DCV) staining procedure for the identification, isolation, and quantitation of radiolabeled dihydrotestosterone (DHT) retention of side population cells. The principle of the side population assay is based on differential efflux of DCV, a cell membrane permeable fluorescent dye, by cells with high ATP binding cassette (ABC) transporter activity. Cells with high ABC transporter activity efflux DCV and fall in the lower left quadrant of a flow cytograph are designated as “side population” cells. This unit emphasizes tissue digestion, DCV staining, flow settings for sorting side population cells and quantitation of radiolabeled DHT retention. PMID:21400686