Are there unmet needs in contraceptive counselling and choice? Findings of the European TANCO Study.

PubMed

Merki-Feld, G S; Caetano, C; Porz, T C; Bitzer, J

2018-05-22

Effective use of contraception requires women to make an informed choice about methods that match their individual needs and expectations. The European Thinking About Needs in Contraception (TANCO) study is a quantitative, online survey of healthcare provider and women's views on aspects of counselling around contraception and contraceptive use. Healthcare providers and women attending their practices for contraceptive counselling were invited to complete online questionnaires. The women's survey explored knowledge and use of contraceptive methods, satisfaction with current method, and interest in receiving more information about all methods. Healthcare provider views were gathered in parallel. A total of 676 healthcare providers and 6027 women completed the online surveys in 11 countries. There was a high prevalence of contraceptive use and general satisfaction with current method across the countries. Fifty-five percent of women were using short-acting contraception (SAC) methods; 19% were using a long-acting reversible contraception (LARC) method. Sixty percent of women were interested in receiving more information about all methods; 73% of women said they would consider LARC if they received more comprehensive information. Healthcare providers tend to underestimate women's interest in receiving information on contraception in general and, more specifically, LARC methods. Despite high levels of use and satisfaction with current methods, women were interested in receiving more information about all contraceptive methods. Greater exploration of women's views on their needs and expectations of contraception could lead to increased knowledge, more effective discussions with healthcare providers and the greater likelihood of informed contraceptive choice.

European Science Notes Information Bulletin. Report on Current European and Middle Eastern Science

DTIC Science & Technology

1992-10-01

oceanographers. This has occurred at a time of current radar systems . The independent develop- rapidly increasing government interest in and fund...over each area in which surface current is ment of the waves (some motions caused by wave determined (for HF systems , averaging time spans action and...Ocean Observing System ; high-resolution model capabilities; ocean- atmosphere interface; Surface Density Depression Pool; forecasting INTRODUCTION tion

Space charge tune shift, fast resonance traversal, and current limits in circular accelerators

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rees, G.H.

1996-06-01

Space charge tune shifts, fast resonance traversals, and current limits are important design issues for low energy, high power circular accelerators. Areas of interest are accumulator rings and fast cycling synchrotrons, and typical applications are for pulsed spallation neutron sources, heavy ion fusion storage ring drivers, and booster injectors for high energy proton and ion facilities. Aspects of the three topics are discussed in the paper. {copyright} {ital 1996 American Institute of Physics.}

Paperbacks Expand High School Collections.

ERIC Educational Resources Information Center

Epstein, Connie C.

1983-01-01

Lists current nonfiction paperback titles of special interest to high school readers submitted by publishers such as Bantam, Harper and Row, MacMillan, and Scholastic from best of titles on their lists. Arrangement is alphabetical by publisher and citations provide author, title, price, publication date, international standard book number, and…

Starch aerogel beads obtained from inclusion complexes prepared from high amylose starch and sodium palmitate

USDA-ARS?s Scientific Manuscript database

Starch aerogels are a class of low density highly porous renewable materials currently prepared from retrograded starch gels and are of interest for their good surface area, porosity, biocompatibility, and biodegradability. Recently, we have reported on starches containing amylose-fatty acid salt h...

Gender, Interest, and Prior Experience Shape Opportunities to Learn Programming in Robotics Competitions

ERIC Educational Resources Information Center

Witherspoon, Eben B.; Schunn, Christian D.; Higashi, Ross M.; Baehr, Emily C.

2016-01-01

Background: Robotics competitions are increasingly popular and potentially provide an on-ramp to computer science, which is currently highly gender imbalanced. However, within competitive robotics teams, student participation in programming is not universal. This study gathered surveys from over 500 elementary, middle, and high school robotics…

Jessica Olstad | NREL

Science.gov Websites

effects of feedstocks and catalysts on gasification products. She is currently the lead engineer on the -based liquid products (such as bio-oil) due to the high oxygen content, high viscosity, and fuel. Olstad is very interested in studying the effects of feeding bio-vapors into the DCR system

Differentiation of High-Functioning Autism and Asperger's Disorder Based on Neuromotor Behaviour

ERIC Educational Resources Information Center

Nayate, Ashwini; Tonge, Bruce J.; Bradshaw, John L.; McGinley, Jennifer L.; Iansek, Robert; Rinehart, Nicole J.

2012-01-01

Autism and Asperger's disorder (AD) are characterised by impairments in social interaction, stereotypic behaviours or restricted interests. Although currently listed as distinct clinical disorders, the validity of their distinction remains controversial. This study examined gait in children with autism and AD. Eleven children with high-functioning…

Kids behind the Camera: Education for the Video Age.

ERIC Educational Resources Information Center

Berwick, Beverly

1994-01-01

Some San Diego teachers created the Montgomery Media Institute to tap the varied talents of young people attending area high schools and junior high schools. Featuring courses in video programming and production, photography, and journalism, this program engages students' interest while introducing them to fields with current employment…

ARRONAX, a high-energy and high-intensity cyclotron for nuclear medicine.

PubMed

Haddad, Ferid; Ferrer, Ludovic; Guertin, Arnaud; Carlier, Thomas; Michel, Nathalie; Barbet, Jacques; Chatal, Jean-François

2008-07-01

This study was aimed at establishing a list of radionuclides of interest for nuclear medicine that can be produced in a high-intensity and high-energy cyclotron. We have considered both therapeutic and positron emission tomography radionuclides that can be produced using a high-energy and a high-intensity cyclotron such as ARRONAX, which will be operating in Nantes (France) by the end of 2008. Novel radionuclides or radionuclides of current limited availability have been selected according to the following criteria: emission of positrons, low-energy beta or alpha particles, stable or short half-life daughters, half-life between 3 h and 10 days or generator-produced, favourable dosimetry, production from stable isotopes with reasonable cross sections. Three radionuclides appear well suited to targeted radionuclide therapy using beta ((67)Cu, (47)Sc) or alpha ((211)At) particles. Positron emitters allowing dosimetry studies prior to radionuclide therapy ((64)Cu, (124)I, (44)Sc), or that can be generator-produced ((82)Rb, (68)Ga) or providing the opportunity of a new imaging modality ((44)Sc) are considered to have a great interest at short term whereas (86)Y, (52)Fe, (55)Co, (76)Br or (89)Zr are considered to have a potential interest at middle term. Several radionuclides not currently used in routine nuclear medicine or not available in sufficient amount for clinical research have been selected for future production. High-energy, high-intensity cyclotrons are necessary to produce some of the selected radionuclides and make possible future clinical developments in nuclear medicine. Associated with appropriate carriers, these radionuclides will respond to a maximum of unmet clinical needs.

High-Resolution of Electron Microscopy of Montmorillonite and Montmorillonite/Epoxy Nanocomposites

DTIC Science & Technology

2005-01-01

AFRL-ML-WP-TP-2006-464 HIGH-RESOLUTION OF ELECTRON MICROSCOPY OF MONTMORILLONITE AND MONTMORILLONITE /EPOXY NANOCOMPOSITES Lawrence F...HIGH-RESOLUTION OF ELECTRON MICROSCOPY OF MONTMORILLONITE AND MONTMORILLONITE /EPOXY NANOCOMPOSITES 5c. PROGRAM ELEMENT NUMBER 62102F 5d...transmission electron microscopy the structure and morphology of montmorillonite (MMT), a material of current interest for use in polymer nanocomposites, was

Correlated selection response of fiber properties measured by high volume instrument and advanced fiber information system in Upland cotton

USDA-ARS?s Scientific Manuscript database

Fiber properties measured by high volume instrument (HVI) and advanced fiber information system (AFIS) are currently being used in Upland cotton (Gossypium hirsutum L.) breeding. It would be interesting to know if selections for parameters measured by the two instrumental systems are equally effici...

Evaluating High School Students' Anxiety and Self-Efficacy towards Biology

ERIC Educational Resources Information Center

Çimen, Osman; Yilmaz, Mehmet

2015-01-01

Anxiety and self-efficacy are among the factors that impact students' performance in biology. The current study aims to investigate high school students' perception of biology anxiety and self-efficacy, in relation to gender, grade level, interest in biology, negative experience associated with biology classes, and teachers' approaches in the…

Marine Algae as Source of Novel Antileishmanial Drugs: A Review.

PubMed

Tchokouaha Yamthe, Lauve Rachel; Appiah-Opong, Regina; Tsouh Fokou, Patrick Valere; Tsabang, Nole; Fekam Boyom, Fabrice; Nyarko, Alexander Kwadwo; Wilson, Michael David

2017-10-29

Leishmaniasis is a vector-borne neglected tropical disease caused by protozoan parasites of the Leishmania genus and transmitted by the female Phlebotomus and Lutzomyia sand flies. The currently prescribed therapies still rely on pentavalent antimonials, pentamidine, paromomycin, liposomal amphotericin B, and miltefosine. However, their low efficacy, long-course treatment regimen, high toxicity, adverse side effects, induction of parasite resistance and high cost require the need for better drugs given that antileishmanial vaccines may not be available in the near future. Although most drugs are still derived from terrestrial sources, the interest in marine organisms as a potential source of promising novel bioactive natural agents has increased in recent years. About 28,000 compounds of marine origin have been isolated with hundreds of new chemical entities. Recent trends in drug research from natural resources indicated the high interest of aquatic eukaryotic photosynthetic organisms, marine algae in the search for new chemical entities given their broad spectrum and high bioactivities including antileishmanial potential. This current review describes prepared extracts and compounds from marine macroalgae along with their antileishmanial activity and provides prospective insights for antileishmanial drug discovery.

Marine Algae as Source of Novel Antileishmanial Drugs: A Review

PubMed Central

Tchokouaha Yamthe, Lauve Rachel; Appiah-Opong, Regina; Tsabang, Nole; Nyarko, Alexander Kwadwo

2017-01-01

Leishmaniasis is a vector-borne neglected tropical disease caused by protozoan parasites of the Leishmania genus and transmitted by the female Phlebotomus and Lutzomyia sand flies. The currently prescribed therapies still rely on pentavalent antimonials, pentamidine, paromomycin, liposomal amphotericin B, and miltefosine. However, their low efficacy, long-course treatment regimen, high toxicity, adverse side effects, induction of parasite resistance and high cost require the need for better drugs given that antileishmanial vaccines may not be available in the near future. Although most drugs are still derived from terrestrial sources, the interest in marine organisms as a potential source of promising novel bioactive natural agents has increased in recent years. About 28,000 compounds of marine origin have been isolated with hundreds of new chemical entities. Recent trends in drug research from natural resources indicated the high interest of aquatic eukaryotic photosynthetic organisms, marine algae in the search for new chemical entities given their broad spectrum and high bioactivities including antileishmanial potential. This current review describes prepared extracts and compounds from marine macroalgae along with their antileishmanial activity and provides prospective insights for antileishmanial drug discovery. PMID:29109372

Interesting experimental results in Japan Proton Accelerator Research Complex H{sup -} ion-source development (invited)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ueno, A.; Oguri, H.; Ikegami, K.

2010-02-15

The following interesting experimental results observed in Japan Proton Accelerator Research Complex (J-PARC) H{sup -} ion-source developments are reviewed. It was proven that almost all of H{sup -} ions were produced with surface reactions in cesium (Cs)-free J-PARC H{sup -} ion-sources. The world's most intense class H{sup -} ion current of 38 mA in Cs-free ion sources for a high-energy linac was attained by an optimal shape and high temperature of the plasma electrode (PE), usage of a lanthanum hexaboride (LaB{sub 6}) filament, and a newly devised high-power constant-current pulsed-arc power supply indispensable for it. It was also proven thatmore » the H{sup -} ion current could be increased to more than 40 mA by optimizing LaB{sub 6}-filament shape. The surface elemental analysis of the PE after operation with a LaB{sub 6}-filament showed that it was coated by boron (B) 95.5%, lanthanum (La) 2.5%, and oxygen (O) 1.9%. The H{sup -} ion current decreased by about 20% when a tungsten (W) filament was used instead of a LaB{sub 6}-filament. The H{sup -} ion current could not be increased by seeding cesium (Cs) if the LaB{sub 6}-filament was used. On the other hand, it was increased to more than 70 mA with much lower arc current of 150 A if Cs was seeded when a W-filament was used.« less

IDENTIFYING ENDOCRINE DISRUPTORS BY HIGH-RESOLUTION MASS SPECTROMETRY

EPA Science Inventory

The EPA is currently interested in human and ecosystem exposure to endocrine disruptors (1)-compounds that interfere with endogenous hormone systems. Possible endocrine disruptors in the environment include certain pesticides, industrial by-products, and pharmaceuticals. Such c...

Metabolic Engineering of Microorganisms for the Production of Higher Alcohols

PubMed Central

Choi, Yong Jun; Lee, Joungmin; Jang, Yu-Sin

2014-01-01

ABSTRACT Due to the increasing concerns about limited fossil resources and environmental problems, there has been much interest in developing biofuels from renewable biomass. Ethanol is currently used as a major biofuel, as it can be easily produced by existing fermentation technology, but it is not the best biofuel due to its low energy density, high vapor pressure, hygroscopy, and incompatibility with current infrastructure. Higher alcohols, including 1-propanol, 1-butanol, isobutanol, 2-methyl-1-butanol, and 3-methyl-1-butanol, which possess fuel properties more similar to those of petroleum-based fuel, have attracted particular interest as alternatives to ethanol. Since microorganisms isolated from nature do not allow production of these alcohols at high enough efficiencies, metabolic engineering has been employed to enhance their production. Here, we review recent advances in metabolic engineering of microorganisms for the production of higher alcohols. PMID:25182323

Metabolic engineering of microorganisms for the production of higher alcohols.

PubMed

Choi, Yong Jun; Lee, Joungmin; Jang, Yu-Sin; Lee, Sang Yup

2014-09-02

Due to the increasing concerns about limited fossil resources and environmental problems, there has been much interest in developing biofuels from renewable biomass. Ethanol is currently used as a major biofuel, as it can be easily produced by existing fermentation technology, but it is not the best biofuel due to its low energy density, high vapor pressure, hygroscopy, and incompatibility with current infrastructure. Higher alcohols, including 1-propanol, 1-butanol, isobutanol, 2-methyl-1-butanol, and 3-methyl-1-butanol, which possess fuel properties more similar to those of petroleum-based fuel, have attracted particular interest as alternatives to ethanol. Since microorganisms isolated from nature do not allow production of these alcohols at high enough efficiencies, metabolic engineering has been employed to enhance their production. Here, we review recent advances in metabolic engineering of microorganisms for the production of higher alcohols. Copyright © 2014 Choi et al.

High Power Laser Hybrid Welding - Challenges and Perspectives

NASA Astrophysics Data System (ADS)

Nielsen, Steen Erik

High power industrial lasers at power levels up to 100 kW is now available on the market. Therefore, welding of thicker materials has become of interest for the heavy metal industry e.g. shipyards and wind mill producers. Further, the power plant industry, producers of steel pipes, heavy machinery and steel producers are following this new technology with great interest. At Lindø Welding Technology (LWT), which is a subsidiary to FORCE Technology, a 32-kwatt disc laser is installed. At this laser facility, welding procedures related to thick section steel applications are developed. Material thicknesses between 40 and 100 mm are currently of interest. This paper describes some of the challenges that are related to the development of the high power hybrid laser welding process as well as to the perspectives for the technology as a production tool for the heavy metal industry.

Trust: Implications for the Army Profession

DTIC Science & Technology

2013-10-01

not competent to handle the tough challenges; that they are not telling us the truth; and that they are more motivated by greed and self -interest...perceive the Army as an opportunistic component of a self - serving civil-military industrial complex, behaving more as a political interest group than a...between cohorts within the Army. Currently, the Army enjoys the public’s trust and the profession is held in high- esteem by most Ameri- cans

Current development of UAV sense and avoid system

NASA Astrophysics Data System (ADS)

Zhahir, A.; Razali, A.; Mohd Ajir, M. R.

2016-10-01

As unmanned aerial vehicles (UAVs) are now gaining high interests from civil and commercialised market, the automatic sense and avoid (SAA) system is currently one of the essential features in research spotlight of UAV. Several sensor types employed in current SAA research and technology of sensor fusion that offers a great opportunity in improving detection and tracking system are presented here. The purpose of this paper is to provide an overview of SAA system development in general, as well as the current challenges facing UAV researchers and designers.

Developing Understanding of Twentieth Century Composition in Junior High School General Music. Final Report.

ERIC Educational Resources Information Center

Adler, Marvin Stanley

To develop an understanding of major 20th century musical styles and compositional techniques in junior high school general music classes, and to utilize rather than ignore student interest in current music, a sequence for units-of-study was developed and tested over a 2-year period in urban junior high schools. The initial units dealt with what…

Bringing Engineering Design into High School Science Classrooms: The Heating/Cooling Unit

ERIC Educational Resources Information Center

Apedoe, Xornam S.; Reynolds, Birdy; Ellefson, Michelle R.; Schunn, Christian D.

2008-01-01

Infusing engineering design projects in K-12 settings can promote interest and attract a wide range of students to engineering careers. However, the current climate of high-stakes testing and accountability to standards leaves little room to incorporate engineering design into K-12 classrooms. We argue that design-based learning, the combination…

In the Public Interest: The Benefits of High Quality Child Care. [Videotape].

ERIC Educational Resources Information Center

Toronto Univ. (Ontario). Centre for Urban and Community Studies.

Noting that, in Canada, 10,000 child care programs serve children and families of diverse cultural and socioeconomic backgrounds, this video examines the characteristics and benefits of high quality programs. The 22-minute video first cites two reasons why quality child care is a current issue: the increasing number of women in the workforce and…

Effects of perfluorinated chemicals on adipocyte development

EPA Science Inventory

Obesity is a growing concern in the US population. Current interest is high in the role played by environmental factors called obesogens that may contribute to obesity through developmental exposure. One class of potential obesogens is the family of perfluorinated chemicals used ...

Natural wax organogels for cookies

USDA-ARS?s Scientific Manuscript database

Organogels formed from vegetable oil and an organogelator have drawn great interest as alternatives to trans fats. Unlike the current alternatives to trans fats such as tropical oils, fully hydrogenated oils and their transesterifed oils containing high contents of saturated fats, organogels can be ...

Interest in use of mHealth technology in HIV prevention and associated factors among high-risk drug users enrolled in methadone maintenance program.

PubMed

Shrestha, Roman; Karki, Pramila; Copenhaver, Michael

2017-09-01

The adoption of mobile technologies for health (mHealth) in healthcare has grown considerably in recent years, but systematic assessment of interest in the use of mHealth in HIV prevention efforts among people who use drugs (PWUD) is lacking. We therefore examined interest in use of mHealth technology in HIV prevention and associated individual-level factors among high-risk PWUD enrolled in methadone maintenance program. A total of 400 HIV-negative PWUD, who reported drug- and/or sex-related risk behaviors completed a standardized assessment using audio computer assisted self-interview (ACASI). Results revealed significant interest in using mHealth-based approaches for specific purposes, including: to receive medication reminders (72.3%), to receive information about HIV risk reduction (65.8%), and to assess HIV risk behaviors (76.5%). Multivariate analysis showed that interest in receiving medication reminders was associated with currently taking medication and being neurocognitively impaired, whereas interest in receiving HIV-risk reduction information was associated with being non-white, married, and perceiving the person was at high-risk for contracting HIV. Similarly, participants' interested in using mHealth for HIV risk behavior assessment was associated with having recently visited a healthcare provider and exhibiting depressive symptoms. Overall, this study demonstrated that high-risk PWUD are interested in using mHealth-based tools as a key part of an HIV prevention approach within a common type of drug treatment settings. Thus, formative research on preferences for design and functionality of mHealth-based HIV prevention tools are now needed, followed by practical development, implementation, and evaluation of these new intervention strategies.

Perceived association between diagnostic and non-diagnostic cues of women's sexual interest: General Recognition Theory predictors of risk for sexual coercion.

PubMed

Farris, Coreen; Viken, Richard J; Treat, Teresa A

2010-01-01

Young men's errors in sexual perception have been linked to sexual coercion. The current investigation sought to explicate the perceptual and decisional sources of these social perception errors, as well as their link to risk for sexual violence. General Recognition Theory (GRT; [Ashby, F. G., & Townsend, J. T. (1986). Varieties of perceptual independence. Psychological Review, 93, 154-179]) was used to estimate participants' ability to discriminate between affective cues and clothing style cues and to measure illusory correlations between men's perception of women's clothing style and sexual interest. High-risk men were less sensitive to the distinction between women's friendly and sexual interest cues relative to other men. In addition, they were more likely to perceive an illusory correlation between women's diagnostic sexual interest cues (e.g., facial affect) and non-diagnostic cues (e.g., provocative clothing), which increases the probability that high-risk men will misperceive friendly women as intending to communicate sexual interest. The results provide information about the degree of risk conferred by individual differences in perceptual processing of women's interest cues, and also illustrate how translational scientists might adapt GRT to examine research questions about individual differences in social perception.

A Simple Analytical Model for Predicting the Detectable Ion Current in Ion Mobility Spectrometry Using Corona Discharge Ionization Sources

NASA Astrophysics Data System (ADS)

Kirk, Ansgar Thomas; Kobelt, Tim; Spehlbrink, Hauke; Zimmermann, Stefan

2018-05-01

Corona discharge ionization sources are often used in ion mobility spectrometers (IMS) when a non-radioactive ion source with high ion currents is required. Typically, the corona discharge is followed by a reaction region where analyte ions are formed from the reactant ions. In this work, we present a simple yet sufficiently accurate model for predicting the ion current available at the end of this reaction region when operating at reduced pressure as in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) or most IMS-MS instruments. It yields excellent qualitative agreement with measurement results and is even able to calculate the ion current within an error of 15%. Additional interesting findings of this model are the ion current at the end of the reaction region being independent from the ion current generated by the corona discharge and the ion current in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) growing quadratically when scaling down the length of the reaction region. [Figure not available: see fulltext.

A Simple Analytical Model for Predicting the Detectable Ion Current in Ion Mobility Spectrometry Using Corona Discharge Ionization Sources.

PubMed

Kirk, Ansgar Thomas; Kobelt, Tim; Spehlbrink, Hauke; Zimmermann, Stefan

2018-05-08

Corona discharge ionization sources are often used in ion mobility spectrometers (IMS) when a non-radioactive ion source with high ion currents is required. Typically, the corona discharge is followed by a reaction region where analyte ions are formed from the reactant ions. In this work, we present a simple yet sufficiently accurate model for predicting the ion current available at the end of this reaction region when operating at reduced pressure as in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) or most IMS-MS instruments. It yields excellent qualitative agreement with measurement results and is even able to calculate the ion current within an error of 15%. Additional interesting findings of this model are the ion current at the end of the reaction region being independent from the ion current generated by the corona discharge and the ion current in High Kinetic Energy Ion Mobility Spectrometers (HiKE-IMS) growing quadratically when scaling down the length of the reaction region. Graphical Abstract ᅟ.

Generation of high-density biskyrmions by electric current

DOE Office of Scientific and Technical Information (OSTI.GOV)

Peng, Licong; Zhang, Ying; He, Min

Much interest has been focused on the manipulation of magnetic skyrmions, including the generation, annihilation, and motion behaviors, for potential applications in spintronics. We experimentally demonstrate that a high-density Bloch-type biskyrmion lattice in MnNiGa can be generated by applying electric current. It is revealed that the density of biskyrmions can be remarkably increased by increasing the electric current, in contrast to the scattered biskyrmions induced by a magnetic field alone. Furthermore, the transition from the ferromagnetic state to the stripe domain structure can be terminated by the electric current, leading to the biskyrmions dominated residual domain pattern. These biskyrmions inmore » such residual domain structure are extremely stable at zero magnetic and electric fields and can further evolve into the high-density biskyrmion lattice over a temperature range from 100 to 330 K. Finally, our experimental findings open up a new pathway for the generation of skyrmion lattice by electric current manipulation.« less

Generation of high-density biskyrmions by electric current

DOE PAGES

Peng, Licong; Zhang, Ying; He, Min; ...

2017-06-16

Much interest has been focused on the manipulation of magnetic skyrmions, including the generation, annihilation, and motion behaviors, for potential applications in spintronics. We experimentally demonstrate that a high-density Bloch-type biskyrmion lattice in MnNiGa can be generated by applying electric current. It is revealed that the density of biskyrmions can be remarkably increased by increasing the electric current, in contrast to the scattered biskyrmions induced by a magnetic field alone. Furthermore, the transition from the ferromagnetic state to the stripe domain structure can be terminated by the electric current, leading to the biskyrmions dominated residual domain pattern. These biskyrmions inmore » such residual domain structure are extremely stable at zero magnetic and electric fields and can further evolve into the high-density biskyrmion lattice over a temperature range from 100 to 330 K. Finally, our experimental findings open up a new pathway for the generation of skyrmion lattice by electric current manipulation.« less

The impact of user centered design on student motivation

NASA Astrophysics Data System (ADS)

Locker, Craig T.

There is a current push for STEM education within the U.S.; however current studies show that students' interest to pursue STEM fields is decreasing as they progress through high school. This lose in interest has shown to have a strong tie to students' perceived levels of motivation towards the subject. The question that this studied set out to answer was if user centered design (UCD) would affect students perceived level of motivation. For this study a treatment of UCD was compared to a traditional high school engineering design curriculum, with the goal to identify if UCD would have a positive effect on the students perceived level of motivation. 59 9th grade high school students from an urban Midwestern city were selected to participate. Students were given a pre and posttest to determine their levels of motivation before and after the comparison or treatment. Analysis showed that students perceived level of intrinsic and extrinsic motivation significantly went up in the treatment group. The study concluded that due to the ease of implementation and low cost of deployment that UCD should be introduced into high school design challenges that focus on developing a solution for an external stakeholder.

Smoking behaviour and preferences for cessation support among clients of an Indigenous community-controlled health service.

PubMed

Cockburn, Nicole; Gartner, Coral; Ford, Pauline J

2018-03-02

Reducing smoking prevalence among Indigenous Australians is a vital part of closing the health gap between Indigenous and non-Indigenous Australians. Community-controlled health clinics are an important setting for delivering smoking cessation advice and assistance. This study measured tobacco and e-cigarette use, knowledge of smoking-related health effects, motivations to quit and interest in cessation aids. Clients of Aboriginal & Torres Strait Islander Community Health Service dental clinics in Southeast Queensland (n = 421) completed a brief written questionnaire while in the waiting room. Nearly half (n = 184, 47%) of the participants currently smoked daily, of which 9% (n = 7) currently used e-cigarettes. Few smokers (8%, n = 13) had no intention to quit smoking. For current smokers, previously used quit methods were abrupt cessation (42%, n = 78), nicotine replacement therapies (NRT; 25%, n = 45), prescription medications (23%, n = 43), e-cigarettes (9%, n = 17) and other methods (3%, n = 6). Current smokers were most interested in cutting down (85%, n = 110), abrupt cessation (75%, n = 98) and free NRT (72%, n = 101). Fewer (34%, n = 36) were interested in purchasing NRT for smoking cessation. Our study found there was interest in accessing smoking cessation aids among the clients of this community-controlled health clinic, particularly if provided free of charge. Embedding smoking cessation advice and assistance into a range of community-controlled health clinics could provide opportunities for addressing the high smoking prevalence among Indigenous Australians. © 2018 Australasian Professional Society on Alcohol and other Drugs.

OCTOCAM: A Workhorse Instrument for the Gemini Telescopes During the Era of LSST

NASA Astrophysics Data System (ADS)

Roming, Peter; van der Horst, Alexander; OCTOCAM Team

2018-01-01

The decade of the 2020s are planned to be an era of large surveys and giant telescopes. A trademark of this era will be the large number of interesting objects observed daily by high-cadence surveys, such as the LSST. Because of the sheer numbers, only a very small fraction of these interesting objects will be observed with extremely large telescopes. The follow up workhorses during this era will be the 8-meter class telescopes and corresponding instruments that are prepared to pursue these interesting objects. One such workhorse instrument is OCTOCAM, a highly efficient instrument designed to probe the time domain window with simulatenous broad-wavelength coverage. OCTOCAM optimizes the use of Gemini for broadband imaging and spectroscopic single-target observations. The instrument is designed for high temporal resolution, broad spectral coverage, and moderate spectral resolution. OCTOCAM was selected as part of the Gemini instrumentation program in early 2017. Here we provide a description of the science cases to be addressed, overall instrument design, and current status.

Seeking science information online: Data mining Google to better understand the roles of the media and the education system.

PubMed

Segev, Elad; Baram-Tsabari, Ayelet

2012-10-01

Which extrinsic cues motivate people to search for science-related information? For many science-related search queries, media attention and time during the academic year are highly correlated with changes in information seeking behavior (expressed by changes in the proportion of Google science-related searches). The data mining analysis presented here shows that changes in the volume of searches for general and well-established science terms are strongly linked to the education system. By contrast, ad-hoc events and current concerns were better aligned with media coverage. The interest and ability to independently seek science knowledge in response to current events or concerns is one of the fundamental goals of the science literacy movement. This method provides a mirror of extrapolated behavior and as such can assist researchers in assessing the role of the media in shaping science interests, and inform the ways in which lifelong interests in science are manifested in real world situations.

Evaluation of new energy cane varieties for Louisiana

USDA-ARS?s Scientific Manuscript database

Renewed interest in U.S bioenergy markets may offer an alternative source of income for Louisiana sugarcane growers. High-fiber sugarcane or energy cane varieties are currently being developed. As with traditional sugarcane varieties, energy-cane varieties need to be evaluated across the sugarca...

Dual Enrollment: The Missing Link to College Readiness

ERIC Educational Resources Information Center

Swanson, Joni

2010-01-01

Dual enrollment programs have sparked the interest of educational researchers and practitioners who want to determine whether offering college courses to high school students might positively affect their persistence in college or other postsecondary education. Current research suggests that participating in dual enrollment programs improves…

"Should I stay or should I go?" Coming off methadone and buprenorphine treatment.

PubMed

Winstock, Adam R; Lintzeris, Nicholas; Lea, Toby

2011-01-01

This study aimed to investigate patient perspectives regarding coming off maintenance opioid substitution treatment (OST). The study explored previous experiences, current interest and concerns about stopping treatment, and perceptions of how and when coming off treatment should be supported. A cross-sectional survey was used. Participants were 145 patients receiving OST at public opioid treatment clinics in Sydney, Australia. Sixty-two percent reported high interest in coming off treatment in the next 6 months. High interest was associated with having discussed coming off treatment with a greater number of categories of people (OR=1.72), not citing concern about heroin relapse (OR=3.18), and shorter duration of current treatment episode (OR=0.99). Seventy-one percent reported previous withdrawal attempts and 23% had achieved opioid abstinence for ≥3 months following a previous withdrawal attempt. Attempts most commonly involved jumping off (59%), and doctor-controlled (52%) or self-controlled (48%) gradual reduction. For future attempts respondents were most interested in doctor-controlled (68%) or self-controlled (41%) gradual reduction. Concerns regarding coming off treatment included withdrawal discomfort (68%), increased pain (50%), and relapse to heroin use (48%). While some patients may require lifetime maintenance, the issue of coming off treatment is important to many patients and should be discussed regularly throughout treatment and where appropriate supported by a menu of clinical options. Crown Copyright © 2010. Published by Elsevier B.V. All rights reserved.

Equilibrium radiative heating tables for Earth entry

NASA Astrophysics Data System (ADS)

Sutton, Kenneth; Hartung, Lin C.

1990-05-01

The recent resurgence of interest in blunt-body atmospheric entry for applications such as aeroassisted orbital transfer and planetary return has engendered a corresponding revival of interest in radiative heating. Radiative heating may be of importance in these blunt-body flows because of the highly energetic shock layer around the blunt nose. Sutton developed an inviscid, stagnation point, radiation coupled flow field code for investigating blunt-body atmospheric entry. The method has been compared with ground-based and flight data, and reasonable agreement has been found. To provide information for entry body studies in support of lunar and Mars return scenarios of interest in the 1970's, the code was exercised over a matrix of Earth entry conditions. Recently, this matrix was extended slightly to reflect entry vehicle designs of current interest. Complete results are presented.

Clinical pathways for primary care: current use, interest and perceived usability.

PubMed

Waters, Richard C; Toy, Jennifer M; Drechsler, Adam

2018-02-26

Translating clinical evidence to daily practice remains a challenge and may improve with clinical pathways. We assessed interest in and usability of clinical pathways by primary care professionals. An online survey was created. Interest in pathways for patient care and learning was assessed at start and finish. Participants completed baseline questions then pathway-associated question sets related to management of 2 chronic diseases. Perceived pathway usability was assessed using the system usability scale. Accuracy and confidence of answers was compared for baseline and pathway-assisted questions. Of 115 participants, 17.4% had used clinical pathways, the lowest of decision support tool types surveyed. Accuracy and confidence in answers significantly improved for all pathways. Interest in using pathways daily or weekly was above 75% for the respondents. There is low utilization of, but high interest in, clinical pathways by primary care clinicians. Pathways improve accuracy and confidence in answering written clinical questions.

Glucose-6-phosphate metabolism in Plasmodium falciparum.

PubMed

Preuss, Janina; Jortzik, Esther; Becker, Katja

2012-07-01

Malaria is still one of the most threatening diseases worldwide. The high drug resistance rates of malarial parasites make its eradication difficult and furthermore necessitate the development of new antimalarial drugs. Plasmodium falciparum is responsible for severe malaria and therefore of special interest with regard to drug development. Plasmodium parasites are highly dependent on glucose and very sensitive to oxidative stress; two observations that drew interest to the pentose phosphate pathway (PPP) with its key enzyme glucose-6-phosphate dehydrogenase (G6PD). A central position of the PPP for malaria parasites is supported by the fact that human G6PD deficiency protects to a certain degree from malaria infections. Plasmodium parasites and the human host possess a complete PPP, both of which seem to be important for the parasites. Interestingly, there are major differences between parasite and human G6PD, making the enzyme of Plasmodium a promising target for antimalarial drug design. This review gives an overview of the current state of research on glucose-6-phosphate metabolism in P. falciparum and its impact on malaria infections. Moreover, the unique characteristics of the enzyme G6PD in P. falciparum are discussed, upon which its current status as promising target for drug development is based. Copyright © 2012 Wiley Periodicals, Inc.

On the Use of PLA-PHB Blends for Sustainable Food Packaging Applications.

PubMed

Arrieta, Marina Patricia; Samper, María Dolores; Aldas, Miguel; López, Juan

2017-08-29

Poly(lactic acid) (PLA) is the most used biopolymer for food packaging applications. Several strategies have been made to improve PLA properties for extending its applications in the packaging field. Melt blending approaches are gaining considerable interest since they are easy, cost-effective and readily available processing technologies at the industrial level. With a similar melting temperature and high crystallinity, poly(hydroxybutyrate) (PHB) represents a good candidate to blend with PLA. The ability of PHB to act as a nucleating agent for PLA improves its mechanical resistance and barrier performance. With the dual objective to improve PLAPHB processing performance and to obtain stretchable materials, plasticizers are frequently added. Current trends to enhance PLA-PHB miscibility are focused on the development of composite and nanocomposites. PLA-PHB blends are also interesting for the controlled release of active compounds in the development of active packaging systems. This review explains the most relevant processing aspects of PLA-PHB based blends such as the influence of polymers molecular weight, the PLA-PHB composition as well as the thermal stability. It also summarizes the recent developments in PLA-PHB formulations with an emphasis on their performance with interest in the sustainable food packaging field. PLA-PHB blends shows highly promising perspectives for the replacement of traditional petrochemical based polymers currently used for food packaging.

An In Vitro Adipocyte Model For Evaluating The Effects Of Environmental Obesogens

EPA Science Inventory

Obesity is a growing concern in the US population. Current interest is high in the role played by environmental factors called obesogens that may contribute to obesity through developmental exposure. Given the importance of understanding the role that these factors play in lipid ...

Determing the feasiblity of chemical imaging of cotton trash

USDA-ARS?s Scientific Manuscript database

There is some interest in the textile community about the identity of cotton trash that has become comingled with cotton lint. Currently, trash is identified visually by human “classers” and instrumentally by the Advanced Fiber Information System (AFIS) and the High Volume Instrument (HVI). Although...

Potential of a national monitoring program for forests to assess change in high-latitude ecosystems

Treesearch

Tara M. Barrett; Andrew N. Gray

2011-01-01

Broad-scale monitoring in Alaska has become of increasing interest due to uncertainty about the potential impacts of changing climate on high-latitude ecosystems. The Forest Inventory and Analysis (FIA) program is a national monitoring program for all public and private forestlands in the US, but the program is not currently implemented in the boreal region of Alaska....

Do Rural and Regional Students in Queensland Experience an ICT "Turn-Off" in the Early High School Years?

ERIC Educational Resources Information Center

Courtney, Lyn; Anderson, Neil

2010-01-01

Students learning in regional, rural and remote locations in Queensland are currently experiencing a "turn-off" in relation to school-based ICT in the first three years of high school. At the same time, students are experiencing increasing levels of interest and motivation from their use of ICT at home. Given the importance of ICT as an…

Human interest meets biodiversity hotspots: A new systematic approach for urban ecosystem conservation.

PubMed

Kasada, Minoru; Matsuba, Misako; Miyashita, Tadashi

2017-01-01

Creating a win-win relationship between biodiversity and human well-being is one of the major current challenges for environmental policy. One way to approach this challenge is to identify sites with both high biodiversity and high human interest in urban areas. Here, we propose a new systematic approach to identify such sites by using land prices and biodiversity indexes for butterflies and birds from a nationwide perspective. As a result, we found sites that are valuable to humans and to other organisms, including national red-list species, and they are located in sites with cultural heritages and near seaside. By referencing the habitat features and landscape characteristics of these sites, we can establish high quality environments that provide a benefit to both humans and biodiversity in urban landscapes.

Spike train generation and current-to-frequency conversion in silicon diodes

NASA Technical Reports Server (NTRS)

Coon, D. D.; Perera, A. G. U.

1989-01-01

A device physics model is developed to analyze spontaneous neuron-like spike train generation in current driven silicon p(+)-n-n(+) devices in cryogenic environments. The model is shown to explain the very high dynamic range (0 to the 7th) current-to-frequency conversion and experimental features of the spike train frequency as a function of input current. The devices are interesting components for implementation of parallel asynchronous processing adjacent to cryogenically cooled focal planes because of their extremely low current and power requirements, their electronic simplicity, and their pulse coding capability, and could be used to form the hardware basis for neural networks which employ biologically plausible means of information coding.

Gender roles and science beliefs and their relationship to science interest

NASA Astrophysics Data System (ADS)

Paolucci, Judith Jean

This study investigated adolescents' views about the nature of science (NOS) and conceptions of their gender identities, and revealed whether these conceptions and views are related to their science interest. Participants were 566 high school students enrolled in chemistry courses at three high schools in a New England state. A questionnaire was used to assess participants' science interest, gender role perceptions, and views about science, as well as to provide background and math and science achievement data. The study found that while student scores of NOS understanding did not differ by gender, some significant differences were noted on the student responses to statements about science. Students with higher-than-average science interest scores responded to these statements differently than students with lower science interest scores; their responses tended to more closely match statements about NOS taken from current reform documents. The study also found that math and science achievement, masculinity scores, and NOS scores accounted for a greater variance of science interest for girls than for boys, though all three also contributed significantly and positively to the regression equation for boys. These predictor variables predicted membership to the lower or higher science interest groups, but could not predict students' career aspiration groups. Thus, other mediating factors not considered in this study may translate high science interest to science career aspiration. The results of this study coed prior research, which found that science and math achievement and masculinity are positively and significantly related to science interest for boy boys and girls. Moreover, the study found that achievement in math and science courses is a greater predictor of science interest for girls than for boys. The results of this study provide a rationale for incorporating the nature of science into the science curriculum. Moreover, since the science interest of boys was also found to be related to NOS understanding, these curricular changes may positively affect all students.

[Intensive care medicine on medical undergraduation: student's perspective].

PubMed

Almeida, Alessandro de Moura; Albuquerque, Ligia Carvalho; Bitencourt, Almir Galvão Vieira; Rolim, Carlos Eduardo Cerqueira; Godinho, Tiana Mascarenhas; Liberato, Maurício Valverde; Oliveira Filho, Fernando Cezar Cabral; Azevedo, Ana Bárbara Galvão de; Neves, Ana Paula Soares da Silva; Martins, Marcelo de Jesus; Silva, João Paulo Maciel; Jesuíno, Paulo André; Souza Filho, Sydney Agareno de

2007-12-01

There are deficiencies on Intensive Medicine (IM) teaching in most of medical undergraduate schools. Those deficiencies may imply damages on their clinical competence. The objective of this study was to analyze current status of IM teaching and the medical undergraduate student interest in this speciality. A cross-sectional study was performed in 2005. We applied a self-reported questionnaire to enrolled students between the sixth and the last semesters of two medical schools from Salvador-Bahia. The questionnaire contained questions about students' interest and knowledge on IM, and opinion on IM teaching in their schools. We studied 570 students. Most of them (57.5%) had never realized a clerkship in intensive care unit (ICU) despite classifying its usefulness as high (mean of 4.14 ± 1.05, in a scale from 1 to 5). IM interest was high or very high in 53.7% of sample. Almost all students (97%) thought that IM topics should be more explored at their curriculum. Only 42.1% reported to be able to assess a critical care patient and this assurance was higher among students with previous clerkship in ICU (p < 0.001). Shock, cardiopulmonary resuscitation and sepsis were the most interesting topics in ICU for students' opinion. This study revealed a high interest in IM among medical undergraduate students. However, most had never practice a clerkship in ICU, demonstrating to be an important factor on undergraduate student performance faced to a critical care patient.

Understanding animal health communication networks among smallholder livestock producers in Australia using stakeholder analysis.

PubMed

Hayes, L; Woodgate, R; Rast, L; Toribio, J-A L M L; Hernández-Jover, M

2017-09-01

Smallholder livestock producers are a diverse population with wide ranging motivations for keeping livestock. The biosecurity risk posed by smallholders has been the subject of much conjecture, with comparisons often made between the level of animal health and biosecurity knowledge of smallholders, versus that of commercial livestock producers. This research aimed to gain a better understanding of current knowledge of smallholder production in Australia, particularly in relation to biosecurity and emergency animal disease, and to investigate the relationships that exist between smallholders and the organisations and individuals from which they seek information, assistance and support. Engagement with stakeholders is an important component of an effective biosecurity communication strategy as the dissemination of biosecurity related information from a single source cannot be expected to satisfy the needs of such a broad ranging population. A qualitative study involving a review of literature, semi-structured interviews with government and non-government stakeholders and the development of smallholder and stakeholder influence and interest grids was undertaken. This paper forms part of a broader mixed methods research project among smallholders. Results from the stakeholder analysis showed variation in the parameters used to define smallholders and in the level of stakeholder involvement. Smallholders identified breeding consultants, other producers, private veterinarians and family, friends and colleagues as having a significant to high level of interest and potential to influence their practices. Government agencies were perceived to only have some level of interest but significant influence. Industry stakeholders and rural suppliers were positioned in the quadrant reflecting perceived low levels of interest and influence. The interest and influence grid developed from stakeholder's perspectives demonstrate a clustering around the mid points for both interest and influence, with the exception of those from industry who described low levels of interest and influence. Commonwealth and State government stakeholders reported a higher level of interest than influence. Veterinarians, both government and private, reported some to significant levels of interest and influence. In contrast to the results from the smallholder grid, rural suppliers reported relatively high levels of both interest and influence. The current study demonstrates that to maximise the effectiveness of biosecurity communication, there is a need for government and industry organisations to further engage with all stakeholders involved with smallholders. Copyright © 2017 Elsevier B.V. All rights reserved.

Is news media related to civic engagement? The effects of interest in and discussions about the news media on current and future civic engagement of adolescents.

PubMed

Erentaitė, Rasa; Žukauskienė, Rita; Beyers, Wim; Pilkauskaitė-Valickienė, Rasa

2012-06-01

This study explored whether discussions about the media, when positively linked to interest in the news media, were related to adolescents' current and future civic engagement. A sample of 2638 adolescents (age M = 17, SD = 1.2), who participated in a school-based study on positive socialization, completed self-report measures on interest in the news media and discussions about the media with parents and friends. Current civic engagement was measured by involvement in volunteering and civic commitments. Future civic engagement was measured by intentions to participate in civic activities in the future. The results showed that more interpersonal discussions about the media and higher interest in the news media both predicted higher civic engagement. Positive links between discussions about the media and current civic engagement were partly mediated by interest in the news media. In addition, interest in the news media together with current civic engagement fully mediated a positive link between discussions about the media and future civic engagement. Moderating effects of gender were observed, with discussions about the media a better predictor of boys' interest in the news media, and current civic engagement a better predictor of girls' future civic engagement. Copyright © 2011 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

Chemoprevention activity of 25-hydroxyvitamin D in the MMTV-PyMT mouse model of breast cancer

USDA-ARS?s Scientific Manuscript database

Development of oncologic conditions is often linked to inadequate vitamin D status. The chemoprevention ability of this molecule is of high interest for breast cancer, the most common malignancy in women worldwide. Current effective vitamin D analogs including the naturally occurring active metabol...

Preliminary studies of cotton non-lint content identification by near-infrared spectroscopy

USDA-ARS?s Scientific Manuscript database

The high demand for cotton production worldwide has presented a need for its standardized classification. There currently exists trained classers and instrumentation to distinguish key cotton quality parameters, such as some trash types and content. However, it is of interest to develop a universal...

NEW TECHNOLOGIES TO SOLVE OLD PROBLEMS AND ADDRESS ISSUES IN RISK ASSESSMENT

EPA Science Inventory

Appropriate utilization of data is an ongoing concern of the regulated industries and the agencies charged with assessing safety or risk. An area of current interest is the possibility that toxicogenomics will enhance our ability to develop higher or high-throughput models for pr...

Fractal and Multifractal Models Applied to Porous Media - Editorial

USDA-ARS?s Scientific Manuscript database

Given the current high level of interest in the use of fractal geometry to characterize natural porous media, a special issue of the Vadose Zone Journal was organized in order to expose established fractal analysis techniques and cutting-edge new developments to a wider Earth science audience. The ...

An Engineering Design STEM Project: T-Shirt Launcher

ERIC Educational Resources Information Center

Fantz, Todd D.; Grant, Melva R.

2013-01-01

The article offers information on making technology education students interested in science and mathematics through the use of a T-shirt launcher design project. This project was designed for junior and senior level high school students who have completed or are currently taking physics and precalculus. The project involves designing an…

Implementing Standards-Based Mathematics Instruction: A Casebook for Professional Development.

ERIC Educational Resources Information Center

Stein, Mary Kay; Smith, Margaret Schwan; Henningsen, Marjorie A.; Silver, Edward A.

Teachers and teacher educators interested in synthesizing their current practice with new mathematics standards will welcome this highly useful volume. The QUASAR Project at the University of Pittsburgh presents prevalent cases of mathematics instruction drawn from their research of nearly 500 classroom lessons. The Mathematical Tasks…

A Project-Based Course on Newton's Laws for Talented Junior High-School Students

ERIC Educational Resources Information Center

Langbeheim, Elon

2015-01-01

Research has shown that project-based learning promotes student interest in science and improves understanding of scientific content. Fostering student motivation is particularly important in accelerated science and technology programmes for talented students, which are often demanding and time-consuming. Current texts provide little guidance on…

Use of Complementary and Alternative Medicine Treatments by Patients with Obstructive Sleep Apnea Hypopnea Syndrome

PubMed Central

Sood, Amit; Narayanan, Sujata; Wahner-Roedler, Dietlind L.; Knudsen, Kayla; Sood, Richa; Loehrer, Laura L.; Hanson, Andrew C.; Kuzniar, Tomasz J.; Olson, Eric J.

2007-01-01

Study Objectives: To assess the proportion of patients with obstructive sleep apnea hypopnea syndrome (OSAHS) reporting previous or current use and interest in future use of complementary and alternative medicine (CAM) therapies. Design: Cross-sectional, point-of-care, anonymous survey. Setting: Sleep disorders center at a Midwest tertiary care center. Participants: Six hundred forty-six consecutive patients undergoing polysomnography. Measurements: The survey instrument comprised 45 items specifically related to CAM therapies, in addition to obtaining baseline data. Results: Response rate was 81% (522/646). A total of 406/522 (78%) patients were diagnosed with OSAHS. Mean age ± SD was 57 ± 14 years, and 267 participants (66%) were men. Overall, 237 (58%) participants reported ever using CAM. Ever and current CAM use specifically for improving sleep was reported by 20% and 7% of the participants, respectively. Twenty-six percent of participants reported ever using biologic products, and 52% reported ever using nonbiologic CAM treatments. A high proportion (58%) of the participants showed interest in future CAM use for improving sleep. Conclusion: A high proportion of patients with OSAHS report previous or current use, and interest in future use, of CAM treatments. This underscores the need to conduct further research in this field. Citation: Sood A; Narayanan S; Wahner-Roedler DL; Knudsen K; Sood R; Loehrer LL; Hanson AC; Kuzniar TJ; Olson EJ. Use of complementary and alternative medicine treatments by patients with obstructive sleep apnea hypopnea syndrome. J Clin Sleep Med 2007;3(6):575-579. PMID:17993037

Transport Gap Opening and High On-Off Current Ratio in Trilayer Graphene with Self-Aligned Nanodomain Boundaries.

PubMed

Wu, Han-Chun; Chaika, Alexander N; Huang, Tsung-Wei; Syrlybekov, Askar; Abid, Mourad; Aristov, Victor Yu; Molodtsova, Olga V; Babenkov, Sergey V; Marchenko, D; Sánchez-Barriga, Jaime; Mandal, Partha Sarathi; Varykhalov, Andrei Yu; Niu, Yuran; Murphy, Barry E; Krasnikov, Sergey A; Lübben, Olaf; Wang, Jing Jing; Liu, Huajun; Yang, Li; Zhang, Hongzhou; Abid, Mohamed; Janabi, Yahya T; Molotkov, Sergei N; Chang, Ching-Ray; Shvets, Igor

2015-09-22

Trilayer graphene exhibits exceptional electronic properties that are of interest both for fundamental science and for technological applications. The ability to achieve a high on-off current ratio is the central question in this field. Here, we propose a simple method to achieve a current on-off ratio of 10(4) by opening a transport gap in Bernal-stacked trilayer graphene. We synthesized Bernal-stacked trilayer graphene with self-aligned periodic nanodomain boundaries (NBs) on the technologically relevant vicinal cubic-SiC(001) substrate and performed electrical measurements. Our low-temperature transport measurements clearly demonstrate that the self-aligned periodic NBs can induce a charge transport gap greater than 1.3 eV. More remarkably, the transport gap of ∼0.4 eV persists even at 100 K. Our results show the feasibility of creating new electronic nanostructures with high on-off current ratios using graphene on cubic-SiC.

On the Maximum and Characteristic Curvature of Current Density of High tc Superconductor Ybco in Flux Relaxation

NASA Astrophysics Data System (ADS)

Ye, Jiping; Sun, Lei; Dai, Xianxi; Dai, Jixin

The flux relaxation is one of important topics in the studies of high Tc superconductivity, because it is related to the energy loss in practical applications. There are many mechanisms, theories and relaxation laws suggested in the literatures. It is very interesting to test them according to the characters and compare them with the experiments. Some people think that the characters of the famous theories are their negative curvature. According our inversion solution, the relaxation ArcG law and experimental data analysis, the relaxation law has both positive and negative signs. This prediction is hopeful to be checked by experiments in future. The current densities of many high Tc superconductors decrease very rapidly in the early time in the relaxation. People do not know what their maximums are. In this work, a theory to determine these maximums of the current densities is presented. The theory is concretely realized by inversion for some real data of the YBCO and their maximum current densities are obtained.

Interest and preferences for contingency management design among addiction treatment clientele.

PubMed

Hartzler, Bryan; Garrett, Sharon

2016-05-01

Despite strong support for its efficacy, debates persist about how dissemination of contingency management is most effectively undertaken. Currently-promoted contingency management methods are empirically-validated, yet their congruence with interests and preferences of addiction treatment clientele is unknown. Such client input is a foundational support for evidence-based clinical practice. This study documented interest in incentives and preferences for fixed-ratio vs. variable-ratio and immediate vs. distal distribution of earned incentives among clients enrolled at three community programs affiliated with the National Institute on Drug Abuse Clinical Trials Network. This multi-site study included anonymous survey completion by an aggregate sample of 358 treatment enrollees. Analyses first ruled out site differences in survey responses, and then tested age and gender as influences on client interest in financial incentives, and preferences for fixed-ratio vs. variable-ratio reinforcement and immediate vs. distal incentive distribution. Interest in different types of $50 incentives (i.e. retail vouchers, transportation vouchers, cash) was highly inter-correlated, with a mean sample rating of 3.49 (0.83) on a five-point scale. While consistent across client gender, age was an inverse predictor of client interest in incentives. A majority of clients stated preference for fixed-ratio incentive magnitude and distal incentive distribution (67% and 63%, respectively), with these preferences voiced by a larger proportion of females. Sample preferences contradict currently-promoted contingency management design features. Future efforts to disseminate contingency management may be more successful if flexibly undertaken in a manner that incorporates the interests and preferences of local client populations.

A study about the interest and previous contact of high school students with Astronomy

NASA Astrophysics Data System (ADS)

Carvalho, C. L.; Zanitti, M. H. R.; Felicidade, B. L.; Gomes, A. D. T.; Dias, E. W.; Coelho, F. O.

2016-04-01

The currently problems in Astronomy teaching in Brazilian Basic Education contrast with the space, and the popularity that astronomical themes have in various media in the country. In this work, we present the results of a study about the interest, and previous contact of high school students from a public school in the city of "São João del-Rei"/MG with topics related to Astronomy. The study and the pedagogical intervention were carried out by students of the PIBID/CAPES/UFSJ. The intervention was performed through an oral exposition with the students' participation, followed by the use of the Stellarium program. The results suggest the majority of students surveyed are interested in Astronomy, and have had some contact with the area. However, some inconsistencies in their responses were identified and examined. The implications for research and for Astronomy Education are discussed. We also make some considerations about relationship between the lack of specific knowledge and the misinformation as one possible reason for the little interest of students in various areas of Science.

Multiphysics Simulations of Hot-Spot Initiation in Shocked Insensitive High-Explosive

NASA Astrophysics Data System (ADS)

Najjar, Fady; Howard, W. M.; Fried, L. E.

2010-11-01

Solid plastic-bonded high-explosive materials consist of crystals with micron-sized pores embedded. Under mechanical or thermal insults, these voids increase the ease of shock initiation by generating high-temperature regions during their collapse that might lead to ignition. Understanding the mechanisms of hot-spot initiation has significant research interest due to safety, reliability and development of new insensitive munitions. Multi-dimensional high-resolution meso-scale simulations are performed using the multiphysics software, ALE3D, to understand the hot-spot initiation. The Cheetah code is coupled to ALE3D, creating multi-dimensional sparse tables for the HE properties. The reaction rates were obtained from MD Quantum computations. Our current predictions showcase several interesting features regarding hot spot dynamics including the formation of a "secondary" jet. We will discuss the results obtained with hydro-thermo-chemical processes leading to ignition growth for various pore sizes and different shock pressures.

Poly(ethylene terephthalate)-based carbons as electrode material in supercapacitors

NASA Astrophysics Data System (ADS)

Domingo-García, M.; Fernández, J. A.; Almazán-Almazán, M. C.; López-Garzón, F. J.; Stoeckli, F.; Centeno, T. A.

A systematic study by complementary techniques shows that PET-waste from plastic vessels is a competitive precursor of carbon electrodes for supercapacitors. PET derived-activated carbons follow the general trends observed for highly porous carbons and display specific capacitances at low current density as high as 197 F g -1 in 2 M H 2SO 4 aqueous electrolyte and 98 F g -1 in the aprotic medium 1 M (C 2H 5) 4NBF 4/acetonitrile. Additionally, high performance has also been achieved at high current densities, which confirms the potential of this type of materials for electrical energy storage. A new method based on the basic solvolysis of PET-waste and the subsequent carbonization seems to be an interesting alternative to obtain porous carbons with enhanced properties for supercapacitors.

Culture and Conflict in the Middle East: Whose Jerusalem? A High School Curriculum. Fulbright-Hays Summer Seminars Abroad, 1998 (Israel and Jordan).

ERIC Educational Resources Information Center

Bloom, Janice

This high school curriculum project/unit of study focuses on providing a framework of ideas for teachers interested in teaching about both the historical and current cultures and conflicts of the Middle East. While the unit is set up to include a more traditional section where both the religious and historical background of Judaism and Islam are…

Planar LTCC transformers for high voltage flyback converters: Part II.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schofield, Daryl; Schare, Joshua M., Ph.D.; Slama, George

This paper is a continuation of the work presented in SAND2007-2591 'Planar LTCC Transformers for High Voltage Flyback Converters'. The designs in that SAND report were all based on a ferrite tape/dielectric paste system originally developed by NASCENTechnoloy, Inc, who collaborated in the design and manufacturing of the planar LTCC flyback converters. The output/volume requirements were targeted to DoD application for hard target/mini fuzing at around 1500 V for reasonable primary peak currents. High voltages could be obtained but with considerable higher current. Work had begun on higher voltage systems and is where this report begins. Limits in material propertiesmore » and processing capabilities show that the state-of-the-art has limited our practical output voltage from such a small part volume. In other words, the technology is currently limited within the allowable funding and interest.« less

Parametric Flutter Analysis of the TCA Configuration and Recommendation for FFM Design and Scaling

NASA Technical Reports Server (NTRS)

Baker, Myles; Lenkey, Peter

1997-01-01

The current HSR Aeroelasticity plan to design, build, and test a full span, free flying transonic flutter model in the TDT has many technical obstacles that must be overcome for a successful program. One technical obstacle is the determination of a suitable configuration and point in the sky to use in setting the scaling point for the ASE models program. Determining this configuration and point in the sky requires balancing several conflicting requirements, including model buildability, tunnel test safety, and the ability of the model to represent the flutter mechanisms of interest. As will be discussed in detail in subsequent sections, the current TCA design exhibits several flutter mechanisms of interest. It has been decided that the ASE models program will focus on the low frequency symmetric flutter mechanism, and will make no attempt to investigate high frequency flutter mechanisms. There are several reasons for this choice. First, it is believed that the high frequency flutter mechanisms are similar in nature to classical wing bending/torsion flutter, and therefore there is more confidence that this mechanism can be predicted using current techniques. The low frequency mode, on the other hand, is a highly coupled mechanism involving wing, body, tail, and engine motion which may be very difficult to predict. Second, the high frequency flutter modes result in very small weight penalties (several hundred pounds), while suppression of the low frequency mechanism inside the flight envelope causes thousands of pounds to be added to the structure. In order to successfully test the low frequency flutter mode of interest, a suitable starting configuration and point in the sky must be identified. The configuration and point in the sky must result in a wind tunnel model that (1) represents the low-frequency wing/body/engine/empennage flutter mechanisms that are unique to HSCT configurations, (2) flutters at an acceptably low frequency in the tunnel, (3) flutters at an acceptably low dynamic pressure in the tunnel, (4) allows sufficient weight for model buildability without inordinately high cost, and (5) has significant separation between the target flutter mechanism and other, potentially catastrophic, flutter mechanisms.

An ionic liquid-gated polymer thin film transistor with exceptionally low "on" resistance

NASA Astrophysics Data System (ADS)

Algarni, Saud A.; Althagafi, Talal M.; Smith, Patrick J.; Grell, Martin

2014-05-01

We report the ionic liquid (IL) gating of a solution processed semiconducting polymer, poly(2,5-bis(3-hexadecylthiophen-2-yl)thieno[3,2-b]thiophene) (PBTTT). IL gating relies on the poor solubility of PBTTT, which requires hot chlorinated benzenes for solution processing. PBTTT, thus, resists dissolution even in IL, which otherwise rapidly dissolves semiconducting polymers. The resulting organic thin film transistors (OTFTs) display low threshold, very high carrier mobility (>3 cm2/Vs), and deliver high currents (in the order of 1 mA) at low operational voltages. Such OTFTs are interesting both practically, for the addressing of current-driven devices (e.g., organic LEDs), and for the study of charge transport in semiconducting polymers at very high carrier density.

Automated Spacecraft Conjunction Assessment at Mars and the Moon

NASA Technical Reports Server (NTRS)

Berry, David; Guinn, Joseph; Tarzi, Zahi; Demcak, Stuart

2012-01-01

Conjunction assessment and collision avoidance are areas of current high interest in space operations. Most current conjunction assessment activity focuses on the Earth orbital environment. Several of the world's space agencies have satellites in orbit at Mars and the Moon, and avoiding collisions there is important too. Smaller number of assets than Earth, and smaller number of organizations involved, but consequences similar to Earth scenarios.This presentation will examine conjunction assessment processes implemented at JPL for spacecraft in orbit at Mars and the Moon.

Perspectives on hypersonic viscous flow research

NASA Technical Reports Server (NTRS)

Cheng, H. K.

1993-01-01

Issues and advances in current hypersonic flow research perceived to be of interest in theoretical fluid/gas dynamics are reviewed. Particular attention is given to the hypersonic aircraft as waverider, computational methods and theoretical development in the study of viscous interaction, and boundary-layer instability and transition studies. In the present framework the study of viscous hypersonic flow faces transition problems of two kinds which represent the two major areas of current research: the turbulence transition in the high Re range and the transition to the free-molecule limit.

High heat-flux self-rotating plasma-facing component: Concept and loading test in TEXTOR

NASA Astrophysics Data System (ADS)

Terra, A.; Sergienko, G.; Hubeny, M.; Huber, A.; Mertens, Ph.; Philipps, V.; The Textor Team

2015-08-01

This contribution reports on the concept of a circular self-rotating and temperature self-stabilising plasma-facing component (PFC), and test of a related prototype in TEXTOR tokamak. This PFC uses the Lorentz force induced by plasma current and magnet field (J × B) to create a torque applied on metallic discs which produce a rotational movement. Additional thermionic current, present at high operation temperatures, brings additional temperature stabilisation ability. This self-rotating disk limiter was exposed to plasma in the TEXTOR tokamak under different radial positions to vary the heat flux. This disk structure shows the interesting ability to stabilise its maximum temperature through the fact that the self-induced rotation is modulated by the thermal emission current. It was observed that the rotation speed increased following both the current collected by the limiter, and the temperature of the tungsten disks.

Human interest meets biodiversity hotspots: A new systematic approach for urban ecosystem conservation

PubMed Central

Kasada, Minoru; Matsuba, Misako; Miyashita, Tadashi

2017-01-01

Creating a win-win relationship between biodiversity and human well-being is one of the major current challenges for environmental policy. One way to approach this challenge is to identify sites with both high biodiversity and high human interest in urban areas. Here, we propose a new systematic approach to identify such sites by using land prices and biodiversity indexes for butterflies and birds from a nationwide perspective. As a result, we found sites that are valuable to humans and to other organisms, including national red-list species, and they are located in sites with cultural heritages and near seaside. By referencing the habitat features and landscape characteristics of these sites, we can establish high quality environments that provide a benefit to both humans and biodiversity in urban landscapes. PMID:28235020

New developments and applications of intense pulsed radiation sources at Sandia National Laboratories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cook, D.

In the past thirty-six months, tremendous strides have been made in x-ray production using high-current z-pinches. Today, the x-ray energy (1.9 MJ) and power (200 TW) output of the Z accelerator (formerly PBFA-II) is the largest available in the laboratory. These z-pinch x-ray sources are being developed for research into the physics of high energy density plasmas of interest in weapon behavior and in inertial confinement fusion. Beyond the Z accelerator current of 20 MA, an extrapolation to the X-1 accelerator level of 60 MA may have the potential to drive high-yield ICF reactions at affordable cost if several challengingmore » technical problems can be overcome. New developments have also taken place at Sandia in the area of high current, mm-diameter electron beams for advanced hydrodynamic radiography. On SABRE, x-ray spot diameters were less than 2 mm with a dose of 100 R at 1 meter in a 40 ns pulse.« less

SiC Nanofibers as Long-Life Lithium-Ion Battery Anode Materials.

PubMed

Sun, Xuejiao; Shao, Changzhen; Zhang, Feng; Li, Yi; Wu, Qi-Hui; Yang, Yonggang

2018-01-01

The development of high energy lithium-ion batteries (LIBs) has spurred the designing and production of novel anode materials to substitute currently commercial using graphitic materials. Herein, twisted SiC nanofibers toward LIBs anode materials, containing 92.5 wt% cubic β-SiC and 7.5 wt% amorphous C, were successfully synthesized from resin-silica composites. The electrochemical measurements showed that the SiC-based electrode delivered a stable reversible capacity of 254.5 mAh g -1 after 250 cycles at a current density of 0.1 A g -1 . It is interesting that a high discharge capacity of 540.1 mAh g -1 was achieved after 500 cycles at an even higher current density of 0.3 A g -1 , which is higher than the theoretical capacity of graphite. The results imply that SiC nanomaterials are potential anode candidate for LIBs with high stability due to their high structure stability as supported with the transmission electron microscopy images.

Tailoring indium oxide nanocrystal synthesis conditions for air-stable high-performance solution-processed thin-film transistors.

PubMed

Swisher, Sarah L; Volkman, Steven K; Subramanian, Vivek

2015-05-20

Semiconducting metal oxides (ZnO, SnO2, In2O3, and combinations thereof) are a uniquely interesting family of materials because of their high carrier mobilities in the amorphous and generally disordered states, and solution-processed routes to these materials are of particular interest to the printed electronics community. Colloidal nanocrystal routes to these materials are particularly interesting, because nanocrystals may be formulated with tunable surface properties into stable inks, and printed to form devices in an additive manner. We report our investigation of an In2O3 nanocrystal synthesis for high-performance solution-deposited semiconductor layers for thin-film transistors (TFTs). We studied the effects of various synthesis parameters on the nanocrystals themselves, and how those changes ultimately impacted the performance of TFTs. Using a sintered film of solution-deposited In2O3 nanocrystals as the TFT channel material, we fabricated devices that exhibit field effect mobility of 10 cm(2)/(V s) and an on/off current ratio greater than 1 × 10(6). These results outperform previous air-stable nanocrystal TFTs, and demonstrate the suitability of colloidal nanocrystal inks for high-performance printed electronics.

Foundational Methane Propulsion Related Technology Efforts, and Challenges for Applications to Human Exploration Beyond Earth Orbit

NASA Technical Reports Server (NTRS)

Brown, Thomas; Klem, Mark; McRight, Patrick

2016-01-01

Current interest in human exploration beyond earth orbit is driving requirements for high performance, long duration space transportation capabilities. Continued advancement in photovoltaic power systems and investments in high performance electric propulsion promise to enable solar electric options for cargo delivery and pre-deployment of operational architecture elements. However, higher thrust options are required for human in-space transportation as well as planetary descent and ascent functions. While high thrust requirements for interplanetary transportation may be provided by chemical or nuclear thermal propulsion systems, planetary descent and ascent systems are limited to chemical solutions due to their higher thrust to weight and potential planetary protection concerns. Liquid hydrogen fueled systems provide high specific impulse, but pose challenges due to low propellant density and the thermal issues of long term propellant storage. Liquid methane fueled propulsion is a promising compromise with lower specific impulse, higher bulk propellant density and compatibility with proposed in-situ propellant production concepts. Additionally, some architecture studies have identified the potential for commonality between interplanetary and descent/ascent propulsion solutions using liquid methane (LCH4) and liquid oxygen (LOX) propellants. These commonalities may lead to reduced overall development costs and more affordable exploration architectures. With this increased interest, it is critical to understand the current state of LOX/LCH4 propulsion technology and the remaining challenges to its application to beyond earth orbit human exploration. This paper provides a survey of NASA's past and current methane propulsion related technology efforts, assesses the accomplishments to date, and examines the remaining risks associated with full scale development.

Recent applications of gas chromatography with high-resolution mass spectrometry.

PubMed

Špánik, Ivan; Machyňáková, Andrea

2018-01-01

Gas chromatography coupled to high-resolution mass spectrometry is a powerful analytical method that combines excellent separation power of gas chromatography with improved identification based on an accurate mass measurement. These features designate gas chromatography with high-resolution mass spectrometry as the first choice for identification and structure elucidation of unknown volatile and semi-volatile organic compounds. Gas chromatography with high-resolution mass spectrometry quantitative analyses was previously focused on the determination of dioxins and related compounds using magnetic sector type analyzers, a standing requirement of many international standards. The introduction of a quadrupole high-resolution time-of-flight mass analyzer broadened interest in this method and novel applications were developed, especially for multi-target screening purposes. This review is focused on the development and the most interesting applications of gas chromatography coupled to high-resolution mass spectrometry towards analysis of environmental matrices, biological fluids, and food safety since 2010. The main attention is paid to various approaches and applications of gas chromatography coupled to high-resolution mass spectrometry for non-target screening to identify contaminants and to characterize the chemical composition of environmental, food, and biological samples. The most interesting quantitative applications, where a significant contribution of gas chromatography with high-resolution mass spectrometry over the currently used methods is expected, will be discussed as well. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

A Multidimensional Analysis of Changes in Mathematics Motivation and Engagement during High School

ERIC Educational Resources Information Center

Plenty, Stephanie; Heubeck, Bernd G.

2013-01-01

Despite concerns about declining interest and enrolments in mathematics, little research has examined change in a broad range of constructs reflecting mathematics motivation and engagement. The current study used an 11-factor model of motivation and engagement to evaluate levels of maths motivation compared to general academic motivation and to…

Graduate Student Support and Manpower Resources in Graduate Science Education, Fall 1970.

ERIC Educational Resources Information Center

National Science Foundation, Washington, DC.

Current data on graduate student support and manpower resources in graduate science education are important to science administrators, educators, and others concerned with the education of highly qualified scientists and engineers and other related manpower issues. They are also of interest to prospective graduate students, vocational counselors,…

Towards Online Delivery of Process-Oriented Guided Inquiry Learning Techniques in Information Technology Courses

ERIC Educational Resources Information Center

Trevathan, Jarrod; Myers, Trina

2013-01-01

Process-Oriented Guided Inquiry Learning (POGIL) is a technique used to teach in large lectures and tutorials. It invokes interaction, team building, learning and interest through highly structured group work. Currently, POGIL has only been implemented in traditional classroom settings where all participants are physically present. However,…

Contemporary Navajo Affairs: Navajo History Volume III, Part B.

ERIC Educational Resources Information Center

Eck, Norman K.

Written specifically for Navajo junior high through college students, but also serving those interested in modern reservation developments and processs, the third volume of a curricular series on Navajo history provides a synthesis of data and pictorial records on current events in the areas of Navajo government, economic development, and health.…

Local Area Networks in Education: Overview, Applications, and Current Limitations.

ERIC Educational Resources Information Center

Piele, Philip K.

Local area networks (LAN) are privately owned communication systems that connect multivendor devices at high speed. As microcomputers become more common in schools, user interest in sharing information, software, and peripherals will increase. A basic understanding of the operation of all LAN's can be gained by knowing four elements: media,…

Oscillations and Analogies: Thomas Young, MD, FRS, Genius.

ERIC Educational Resources Information Center

Martindale, Colin

2001-01-01

Thomas Young was a renowned genius in his time who did important work in many scientific disciplines. In today's specialized environment, scientists in each discipline do not appreciate his work. Despite his current obscurity, Young exemplifies traits found in a first-order genius (analogical thinking, high intelligence, hard work, wide interests,…

Q & A with Ed Tech Leaders: Interview with Stavros Demetriadis

ERIC Educational Resources Information Center

Fulgham, Susan M.; Shaughnessy, Michael F.

2013-01-01

Stavros Demetriadis is currently an Assistant Professor with the Department of Informatics, Aristotle University of Thessaloniki (AUTh) in Greece. He also earned his Bachelor's degree in Physics and a Master Diploma in Electronic Physics from AUTh. He became interested in information and communications technologies when he was a high school…

High School Graduation Rates across English Learner Student Subgroups in Arizona. REL 2017-205

ERIC Educational Resources Information Center

Huang, Min; Haas, Eric; Zhu, Niufeng; Tran, Loan

2016-01-01

Recent studies have documented differences in academic achievement between current and former English learner students. These differences validate calls for more focused analyses of achievement across English learner student subgroups. Specifically, there is interest in examining variation in academic success based on the amount of time a student…

The Perception of Error in Production Plants of a Chemical Organisation

ERIC Educational Resources Information Center

Seifried, Jurgen; Hopfer, Eva

2013-01-01

There is considerable current interest in error-friendly corporate culture, one particular research question being how and under what conditions errors are learnt from in the workplace. This paper starts from the assumption that errors are inevitable and considers key factors which affect learning from errors in high responsibility organisations,…

Chapter 15: Forest Trees

Treesearch

Donald L. Rockwood; Matias Kirst; Judson G. Isebrands; J.Y. Zhu

2012-01-01

Interest in renewable biomass for fuel, chemicals, and materials is high (e.g., Rocha et al. 2002), as many products currently derived from petrochemicals can be produced from biomass (Sims et al. 2006). Biomass can be converted into many energy products and chemicals: e.g., alcohol by fermenting cellulose, charcoal, bio-oil, and gases by biomass pyrolysis (Khesghi et...

Benchmark Problems for Space Mission Formation Flying

NASA Technical Reports Server (NTRS)

Carpenter, J. Russell; Leitner, Jesse A.; Folta, David C.; Burns, Richard

2003-01-01

To provide a high-level focus to distributed space system flight dynamics and control research, several benchmark problems are suggested for space mission formation flying. The problems cover formation flying in low altitude, near-circular Earth orbit, high altitude, highly elliptical Earth orbits, and large amplitude lissajous trajectories about co-linear libration points of the Sun-Earth/Moon system. These problems are not specific to any current or proposed mission, but instead are intended to capture high-level features that would be generic to many similar missions that are of interest to various agencies.

Hydrodynamic Microgap Voltammetry under Couette Flow Conditions: Electrochemistry at a Rotating Drum in Viscous Poly(ethylene glycol).

PubMed

Hotchen, Christopher E; Nguyen, H Viet; Fisher, Adrian C; Frith, Paul E; Marken, Frank

2015-07-21

Electrochemical processes in highly viscous media such as poly(ethylene glycol) (herein PEG200) are interesting for energy-conversion applications, but problematic due to slow diffusion causing low current densities. Here, a hydrodynamic microgap experiment based on Couette flow is introduced for an inlaid disc electrode approaching a rotating drum. Steady-state voltammetric currents are independent of viscosity and readily increased by two orders of magnitude with further potential to go to higher rotation rates and nanogaps. A quantitative theory is derived for the prediction of currents under high-shear Couette flow conditions and generalised for different electrode shapes. The 1,1'-ferrocene dimethanol redox probe in PEG200 (D=1.4×10 -11  m 2  s -1 ) is employed and data are compared with 1) a Levich-type equation expressing the diffusion-convection-limited current and 2) a COMSOL simulation model providing a potential-dependent current trace. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

On the Use of PLA-PHB Blends for Sustainable Food Packaging Applications

PubMed Central

Arrieta, Marina Patricia; Samper, María Dolores; Aldas, Miguel; López, Juan

2017-01-01

Poly(lactic acid) (PLA) is the most used biopolymer for food packaging applications. Several strategies have been made to improve PLA properties for extending its applications in the packaging field. Melt blending approaches are gaining considerable interest since they are easy, cost-effective and readily available processing technologies at the industrial level. With a similar melting temperature and high crystallinity, poly(hydroxybutyrate) (PHB) represents a good candidate to blend with PLA. The ability of PHB to act as a nucleating agent for PLA improves its mechanical resistance and barrier performance. With the dual objective to improve PLAPHB processing performance and to obtain stretchable materials, plasticizers are frequently added. Current trends to enhance PLA-PHB miscibility are focused on the development of composite and nanocomposites. PLA-PHB blends are also interesting for the controlled release of active compounds in the development of active packaging systems. This review explains the most relevant processing aspects of PLA-PHB based blends such as the influence of polymers molecular weight, the PLA-PHB composition as well as the thermal stability. It also summarizes the recent developments in PLA-PHB formulations with an emphasis on their performance with interest in the sustainable food packaging field. PLA-PHB blends shows highly promising perspectives for the replacement of traditional petrochemical based polymers currently used for food packaging. PMID:28850102

Interest in dental implantology and preferences for implant therapy: a survey of Victorian dentists.

PubMed

Cheung, M C; Kao, Plh; Lee, N; Sivathasan, D; Vong, C W; Zhu, J; Polster, A; Darby, I

2016-12-01

The purpose of this study was to gauge dentists' interest, knowledge and training in implantology, and to compare their treatment preferences with current literature. Subsequently, this information may be used to evaluate implantology education pathways. A cross-sectional postal survey of 600 randomly selected dentists registered with the Dental Practice Board of Victoria was conducted. Respondents were asked about background, interest and training in implantology, and implant treatment preferences. Results were analysed according to primary practice location, decade of graduation and attendance at continuing professional development (CPD) programmes. One hundred and seventy-six questionnaires were included for analysis. In general, dentists rate their implant knowledge, interest and enjoyment in restoring implants favourably. No differences were found between city and country practitioners, and different graduation decades. The level of CPD significantly influenced treatment preferences. Practitioners were generally unwilling to treat patients taking bisphosphonates, or to perform grafting procedures. Most dentists provide common services to treat peri-implant conditions. Direct-to-fixture is the most popular fixture-abutment connection. Overall, there is a high level of implant knowledge corresponding to current evidence in the literature. Level of CPD attendance is the most important factor in dentists' willingness to provide more implant therapy options. © 2016 Australian Dental Association.

High-Content Electrophysiological Analysis of Human Pluripotent Stem Cell-Derived Cardiomyocytes (hPSC-CMs).

PubMed

Kong, Chi-Wing; Geng, Lin; Li, Ronald A

2018-01-01

Considerable interest has been raised to develop human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) as a model for drug discovery and cardiotoxicity screening. High-content electrophysiological analysis of currents generated by transmembrane cell surface ion channels has been pursued to complement such emerging applications. Here we describe practical procedures and considerations for accomplishing successful assays of hPSC-CMs using an automated planar patch-clamp system.

76 FR 66758 - Remedies for Small Copyright Claims

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-27

... legal system hinders or prevents copyright owners from pursuing copyright infringement claims that have... helpful and viable. A. Challenges of the Current Legal System Currently, copyright owners interested in... Office is interested in learning about alternatives to the current legal system that might help alleviate...

Interest in cosmetic improvement as a marker for tanning behavior: a survey of 1602 respondents

PubMed Central

Cathcart, Shelley; DeCoster, Jamie; Northington, Marian; Cantrell, Wendy; Elmets, Craig A.; Elewski, Boni E.

2011-01-01

Dermatologists see many patients interested in improving their physical appearance through cosmetic procedures or medical means. Dermatologists frequently counsel patients on sun protection as well, particularly those with a personal or family history of skin cancer, sun-sensitive dermatoses or those with obvious sun damage. Our objective in this study was to identify novel markers of skin cancer risk which may aid dermatologists in targeting extra sun protection counseling for certain groups. A sixteen-question survey was distributed to subjects nineteen years of age and older in public areas of downtown Birmingham, Alabama in August and September of 2008. Overall, about 40% of both genders reported that they were highly concerned that current sun exposure could cause skin cancer. Participants interested in at least one appearance-related questionnaire item were significantly more likely than those not interested to rate tanned skin as highly important (31.6% vs 17.5%, p<0.001), and to report regret for previous sun exposure (12.5% vs 3.6%, p<0.001). Subjects who thought tanned skin was important were significantly more likely to report interest in improving their appearance through cosmetic procedures and medical means. We conclude that individuals with an interest in improving their physical appearance through cosmetic procedures or medical means may be especially in need of sun protection counseling. PMID:21332909

Interest in cosmetic improvement as a marker for tanning behavior: a survey of 1602 respondents.

PubMed

Cathcart, Shelley; DeCoster, Jamie; Northington, Marian; Cantrell, Wendy; Elmets, Craig A; Elewski, Boni E

2011-03-01

Dermatologists see many patients interested in improving their physical appearance through cosmetic procedures or medical means. Dermatologists frequently counsel patients on sun protection as well, particularly those with a personal or family history of skin cancer, sun-sensitive dermatoses or those with obvious sun damage. Our objective in this study was to identify novel markers of skin cancer risk, which may aid dermatologists in targeting extra sun protection counseling for certain groups. A 16-question survey was distributed to subjects 19 years of age and older in public areas of downtown Birmingham, Alabama in August and September of 2008. Overall, about 40% of both genders reported that they were highly concerned that current sun exposure could cause skin cancer. Participants interested in at least one appearance-related questionnaire item were significantly more likely than those not interested to rate tanned skin as highly important (31.6%vs. 17.5%, P<0.001), and to report regret for previous sun exposure (12.5%vs. 3.6%, P<0.001). Subjects who thought tanned skin was important were significantly more likely to report interest in improving their appearance through cosmetic procedures and medical means. We conclude that individuals with an interest in improving their physical appearance through cosmetic procedures or medical means may be especially in need of sun protection counseling. © 2011 Wiley Periodicals, Inc.

Consumer awareness and interest toward sodium reduction trends in Korea.

PubMed

Kim, Mina K; Lee, Kwang-Geun

2014-07-01

Reduction of dietary sodium intake by lowering amount of sodium in foods is a global industry target. Quantitative information on current consumer knowledge of sodium reduction trends in Korea is unknown. The objective of this study was to quantify the consumer knowledge and awareness of sodium and salt reduction in foods and to characterize consumer interest in health labeling on the food package. Additionally, comparison of consumer knowledge status between Korea and United States was followed. Consumers (n = 289) participated in an internet survey designed to gauge consumer knowledge and attitudes toward dietary sodium, the sodium content in representative food products (n = 27), and their interest toward specific health claims, including sodium labeling. Questions regarding demographics as well as consumption characteristics were asked. Sodium knowledge index and saltiness belief index were calculated based on the number of correct responses regarding the salt level and sodium content in given food products. Kano analysis was conducted to determine the role of nutrition labels in consumer satisfaction with products. Current consumer knowledge on the sodium content in food products was high, and consumers were adept at matching the sodium content with the salty taste intensity of food products. Consumers' knowledge of the relationship between diets high in sodium and an increased risk of developing previously reported sodium-related diseases, such as hypertension, coronary heart disease, kidney disease, and stomach cancer, were also high. Information on the nutrition panel that influences the consumer satisfaction (trans-fat, sodium, ingredient list, and country of origin) as well as adjective-nutrition claim pairs that appeal positively to purchase intent of the product were identified. This work provided the current status of Korean consumer knowledge on the amount of sodium in food and that sodium can be a risk factor of developing chronic diseases. It also provided practical information to food marketers on what consumers like and what they want to see on product labels in Korea. © 2014 Institute of Food Technologists®

Eyeballs in the Fridge: Sources of early interest in science

NASA Astrophysics Data System (ADS)

Maltese, Adam V.; Tai, Robert H.

2010-03-01

This paper examines the experiences reported by scientists and graduate students regarding the experiences that first engaged them in science. The interviews analysed for this paper come from Project Crossover, a mixed-methods study of the transition from graduate student to PhD scientist in the fields of chemistry and physics. This analysis involved review of 116 interviews collected from graduate students and scientists and focused on the timing, source, and nature of their earliest interest in science. The majority (65%) of participants reported that their interest in science began before middle school. Females were more likely to report that their interest was sparked by school-related activities, while most males recounted self-initiated activities. Our findings indicate that current policy efforts (which focus on high school science reform) to increase the numbers of students studying in the science fields, may be misguided.

5 CFR 831.613 - Election of insurable interest annuity.

Code of Federal Regulations, 2013 CFR

2013-01-01

... insurable interest annuity is cancelled if— (i) The retiree fails to qualify to receive the insurable... insurable interest is presumed to exist with— (i) The current spouse; (ii) The current same-sex domestic... same-sex domestic partner; (vi) A person to whom the employee or Member is engaged to be married, or a...

5 CFR 831.613 - Election of insurable interest annuity.

Code of Federal Regulations, 2014 CFR

2014-01-01

... insurable interest annuity is cancelled if— (i) The retiree fails to qualify to receive the insurable... insurable interest is presumed to exist with— (i) The current spouse; (ii) The current same-sex domestic... same-sex domestic partner; (vi) A person to whom the employee or Member is engaged to be married, or a...

Cross-Cultural Communication in Oncology: Challenges and Training Interests.

PubMed

Weber, Orest; Sulstarova, Brikela; Singy, Pascal

2016-01-01

To survey oncology nurses and oncologists about difficulties in taking care of culturally and linguistically diverse patients and about interests in cross-cultural training.
. Descriptive, cross-sectional.
. Web-based survey.
. 108 oncology nurses and 44 oncologists. 
. 31-item questionnaire derived from preexisting surveys in the United States and Switzerland.
. Self-rated difficulties in taking care of culturally and linguistically diverse patients and self-rated interests in cross-cultural training.
. All respondents reported communication difficulties in encounters with culturally and linguistically diverse patients. Respondents considered the absence of written materials in other languages, absence of a shared common language with patients, and sensitive subjects (e.g., end of life, sexuality) to be particularly problematic. Respondents also expressed a high level of interest in all aspects of cross-cultural training (task-oriented skills, background knowledge, reflexivity, and attitudes). Nurses perceived several difficulties related to care of migrants as more problematic than physicians did and were more interested in all aspects of cross-cultural training. 
. The need for cross-cultural training is high among oncology clinicians, particularly among nurses.
. The results reported in the current study may help nurses in decision-making positions and educators in introducing elements of cross-cultural education into oncology curricula for nurses. Cross-cultural training should be offered to oncology nurses.

Antepartum Fetal Monitoring and Spectral Analysis of Preterm Birth Risk

NASA Astrophysics Data System (ADS)

Păsăricără, Alexandru; Nemescu, Dragoş; Arotăriţei, Dragoş; Rotariu, Cristian

2017-11-01

The monitoring and analysis of antepartum fetal and maternal recordings is a research area of notable interest due to the relatively high value of preterm birth. The interest stems from the improvement of devices used for monitoring. The current paper presents the spectral analysis of antepartum heart rate recordings conducted during a study in Romania at the Cuza Voda Obstetrics and Gynecology Clinical Hospital from Iasi between 2010 and 2014. The study focuses on normal and preterm birth risk subjects in order to determine differences between these two types or recordings in terms of spectral analysis.

Perspectives on marijuana use and effectiveness: A survey of NARCOMS participants.

PubMed

Cofield, Stacey S; Salter, Amber; Tyry, Tuula; Crowe, Christina; Cutter, Gary R; Fox, Robert J; Marrie, Ruth Ann

2017-08-01

Interest in and use of marijuana by persons with multiple sclerosis (MS) has increased. While potential benefits have been reported, so have concerns about potential risks. Few large studies have been conducted about the perceptions and current usage of marijuana and medical cannabinoids in persons with MS. Participants in the North American Research Committee on Multiple Sclerosis (NARCOMS) registry were surveyed in 2014 regarding legality and history of marijuana usage, both before and after diagnosis with MS. A total of 5,481 participants responded, with 78.2% female, 90% relapsing disease at onset, and a current mean age of 55.5 (10.2) years. Sixty-four percent had tried marijuana prior to their MS diagnosis, 47% have considered using for their MS, 26% have used for their MS, 20% have spoken with their physician about use, and 16% are currently using marijuana. Ninety-one percent think marijuana should be legal in some form. Men, those with higher disability, current and past nicotine smokers, and younger age were associated with a higher likelihood of current use. The majority of responders favor legalization and report high interest in the use of marijuana for treatment of MS symptoms, but may be reluctant to discuss this with health care providers. Health care providers should systematically inquire about use of marijuana.

Open Science CBS Neuroimaging Repository: Sharing ultra-high-field MR images of the brain.

PubMed

Tardif, Christine Lucas; Schäfer, Andreas; Trampel, Robert; Villringer, Arno; Turner, Robert; Bazin, Pierre-Louis

2016-01-01

Magnetic resonance imaging at ultra high field opens the door to quantitative brain imaging at sub-millimeter isotropic resolutions. However, novel image processing tools to analyze these new rich datasets are lacking. In this article, we introduce the Open Science CBS Neuroimaging Repository: a unique repository of high-resolution and quantitative images acquired at 7 T. The motivation for this project is to increase interest for high-resolution and quantitative imaging and stimulate the development of image processing tools developed specifically for high-field data. Our growing repository currently includes datasets from MP2RAGE and multi-echo FLASH sequences from 28 and 20 healthy subjects respectively. These datasets represent the current state-of-the-art in in-vivo relaxometry at 7 T, and are now fully available to the entire neuroimaging community. Copyright © 2015 Elsevier Inc. All rights reserved.

AMON: Transition to real-time operations

NASA Astrophysics Data System (ADS)

Cowen, D. F.; Keivani, A.; Tešić, G.

2016-04-01

The Astrophysical Multimessenger Observatory Network (AMON) will link the world's leading high-energy neutrino, cosmic-ray, gamma-ray and gravitational wave observatories by performing real-time coincidence searches for multimessenger sources from observatories' subthreshold data streams. The resulting coincidences will be distributed to interested parties in the form of electronic alerts for real-time follow-up observation. We will present the science case, design elements, current and projected partner observatories, status of the AMON project, and an initial AMON-enabled analysis. The prototype of the AMON server has been online since August 2014 and processing archival data. Currently, we are deploying new high-uptime servers and will be ready to start issuing alerts as early as winter 2015/16.

Solar array module plasma interactions experiment (SAMPIE) - Science and technology objectives

NASA Technical Reports Server (NTRS)

Hillard, G. B.; Ferguson, Dale C.

1993-01-01

The solar array module plasma interactions experiment (SAMPIE) is an approved NASA flight experiment manifested for Shuttle deployment in early 1994. The SAMPIE experiment is designed to investigate the interaction of high voltage space power systems with ionospheric plasma. To study the behavior of solar cells, a number of solar cell coupons (representing design technologies of current interest) will be biased to high voltages to measure both arcing and current collection. Various theories of arc suppression will be tested by including several specially modified cell coupons. Finally, SAMPIE will include experiments to study the basic nature of arcing and current collection. This paper describes the rationale for a space flight experiment, the measurements to be made, and the significance of the expected results. A future paper will present a detailed discussion of the engineering design.

Microfiber Optical Sensors: A Review

PubMed Central

Lou, Jingyi; Wang, Yipei; Tong, Limin

2014-01-01

With diameter close to or below the wavelength of guided light and high index contrast between the fiber core and the surrounding, an optical microfiber shows a variety of interesting waveguiding properties, including widely tailorable optical confinement, evanescent fields and waveguide dispersion. Among various microfiber applications, optical sensing has been attracting increasing research interest due to its possibilities of realizing miniaturized fiber optic sensors with small footprint, high sensitivity, fast response, high flexibility and low optical power consumption. Here we review recent progress in microfiber optical sensors regarding their fabrication, waveguide properties and sensing applications. Typical microfiber-based sensing structures, including biconical tapers, optical gratings, circular cavities, Mach-Zehnder interferometers and functionally coated/doped microfibers, are summarized. Categorized by sensing structures, microfiber optical sensors for refractive index, concentration, temperature, humidity, strain and current measurement in gas or liquid environments are reviewed. Finally, we conclude with an outlook for challenges and opportunities of microfiber optical sensors. PMID:24670720

Fear versus humor: the impact of sensation seeking on physiological, cognitive, and emotional responses to antialcohol abuse messages.

PubMed

Lee, Moon J; Shin, Mija

2011-01-01

This study investigates the differences in physiological, cognitive, and emotional responses to existing emotional antialcohol abuse advertisements (fear vs. humor appeal) between high and low sensation seekers. A 2 (Message Type) x 2 (Sensation-Seeking Tendency) x 4 (Message Repetition) mixed-model experiment with repeated measures was conducted with 71 college students. The results, based on self-reports, indicated that fear messages generated more interest and perceived danger of excessive drinking regardless of sensation-seeking tendency, whereas humorous messages were rated as more likeable than fear messages, and the difference was bigger among low sensation seekers than among high sensation seekers. One interesting finding was that for both fear and humor appeals, low sensation seekers showed greater emotional responses (greater corrugators activities and greater zygomatic activities) than high sensation seekers overall. The implications of the current study as well as suggestions for future study were discussed.

Psychotraumatology in the Netherlands

PubMed Central

Vermetten, Eric; Olff, Miranda

2013-01-01

The contribution to psychotrauma literature from Dutch authors has a long tradition. The relatively high lifetime prevalence of trauma and posttraumatic stress disorder (PTSD) is not unique for the Netherlands and does not fully explain the interest in trauma and its consequences. In this overview of psychotraumatology in the Netherlands, we will discuss some of the key events and processes that contribute to the current interest. We outlined the historical basis and development of the field in the Netherlands, including the impact of World War II, the effects of major man-made or natural disasters, engagement in military conflicts, as well as smaller scale traumatic events like sexual abuse and traffic accidents. The liberal and open culture may have reduced stigma to trauma, while other sociocultural aspects may have contributed to increased prevalence. Finally, we describe Dutch psychotraumatology today and how history and culture have shaped the current scientific basis. PMID:23671764

The Role of the Urologist in Treating Patients with Hormone-Refractory Prostate Cancer

PubMed Central

Crawford, E. David

2003-01-01

Objectives: To ascertain what percentage of urologists’ oncology practice is dedicated to the care of prostate cancer patients and to determine urologists’ attitudes towards the treatment of patients with metastatic and hormone-refractory prostate cancer (HRPC). An additional objective is to determine urologists’ interest in administering various types of chemotherapy in HRPC patients. Materials and Methods: The American Urological Association (AUA) directory of practicing urologists was obtained, and 3000 randomly selected members of the AUA, as well as the complete list of 168 Society of Urologic Oncology (SUO) members, were chosen for the mailing of a 16-item questionnaire. The urologists were asked about how many of their patients have prostate cancer, how many have metastatic disease, and how many have HRPC and are currently receiving intravenous (IV) chemotherapy. In addition, the urologists were queried regarding their level of interest in learning about chemotherapy options as well as learning how to administer chemotherapy. Results: A total of 654 survey questionnaires were completed and returned for tabulation, resulting in a 21% effective response rate. Sixty-four percent of the responding urologists’ cancer patients had prostate cancer, 21% had metastatic disease, and 19% had HRPC; only 4% of the urologists currently administer IV chemotherapy themselves. When asked to describe their interest in learning how to deliver and be reimbursed for IV chemotherapy, 26% expressed an extremely low level of interest, 23% a low level of interest, 31% a high level of interest, and 17% an extremely high level of interest. The results of other questions are presented and correlated with the number of years the urologists have been in practice and other demographic data. Conclusions: The management of prostate cancer comprises a major portion of urologists’ practices. Almost one half (48%) of the urologists in this survey were interested in administering and being reimbursed for IV chemotherapy. Several chemotherapy regimens have been shown to improve quality of life in patients with HRPC, yet only about 30% of these patients were referred for chemotherapy. If more urologists were able to deliver these drugs, then the number of patients referred for chemotherapy would likely increase, as would accrual to important clinical trials in HRPC. The results of this survey suggest that methods to implement the training and reimbursement of urologists in the use of chemotherapy regimens should be investigated. PMID:16986047

75 FR 58462 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of a Proposed Rule Change...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-24

... resting interest exceeds the Defined Limit, the Market Maker must enter new interest at a price not more than the Designated Percentage of 8% away from the NBBO (or identify to the Corporation current resting... Corporation current resting interest that satisfies the Market Maker's obligation). The Exchange proposes that...

Satellite Ocean Data Tools in the high school classroom.

NASA Astrophysics Data System (ADS)

Tweedie, M.; Snyder, H. D.

2007-12-01

The NASA-sponsored Ocean Motion website (http://www.oceanmotion.org) documents the story of humankind's interest in and observations of surface currents from the early seafaring Polynesians to present day satellite observations. Ocean surface current patterns impact our lives through their influences on the weather, climate, commerce, natural disasters and sea life. The Ocean Motion web site provides inquiry based, classroom ready materials for high school teachers and students to study ocean surface currents. In addition to the information resources posted on the website, there are also investigations that lead students to explore patterns and relationships through data products (color- coded map images, time series graphs and data tables). These investigations are done through an interactive browser interface that provides access to a wealth of oceanography data. This presentation focuses on use of surface current data and models in student investigations to illustrate application of basic science principles found in high school science curriculum. Skills developed using data to discover patterns and relationships will serve students in other courses as well as empower them to become stewards of the Earths environment.

Science vs. Sports: Motivation and Self-Concepts of Participants in Different School Competitions

ERIC Educational Resources Information Center

Höffler, Tim Niclas; Bonin, Victoria; Parchmann, Ilka

2017-01-01

Competitions are discussed as a measure to foster students' interest, especially for highly gifted and talented students. In the current study, participants of a cognitive school competition in science were compared to non-participants of the same age group (14-15) who either did not participate in any competition or who participated in a…

Shining Light into Cosmic Dark Ages

NASA Astrophysics Data System (ADS)

Fialkov, Anastasia

2018-06-01

Exploration of the early Universe is ongoing. One of the most interesting probes of the epoch is the redshifted 21-cm line of neutral hydrogen. Modeling of this signal is difficult due to large uncertainties in both astrophysical and cosmological parameters that describe the high redshift Universe. In my talk I will discuss current theoretical understanding and the status of modeling.

Comparison of soybean and cottonseed oils upon hydrogenation with nickel, palladium and platinum catalysts

USDA-ARS?s Scientific Manuscript database

There is current interest in reducing the trans fatty acids (TFA) in hydrogenated vegetable oils because consumption of foods high in TFA has been linked to increased serum cholesterol content. In this work, hydrogenation was carried out on soybean oil and cottonseed oil at two pressures (2 and 5 b...

Faculty Roles: A Primer for Students and Professionals Interested in Careers in Academia

ERIC Educational Resources Information Center

Harris, Bryn; Sullivan, Amanda L.

2012-01-01

Faculty shortage is a major concern for the field of school psychology in the United States. Graduate students are not entering the field at a rate representative of the current need (Clopton & Haselhuhn, 2009). The reasons for this are multifaceted, but some studies have pointed to perceived high levels of job stress, perceived inadequate…

Studies in Teaching. 1995 Research Digest. Papers Presented at the Annual Research Forum (Winston-Salem, North Carolina, December 1995).

ERIC Educational Resources Information Center

McCoy, Leah P., Ed.

This is a collection of papers reporting student research projects at the Annual Research Forum, Department of Education, Wake Forest University (North Carolina). They include: "Student Interest in Studying World History in Relation to Current Events" (Conan Arthur); "Perceptions of High School Student Athletes and Athletics"…

Postgraduate Preferences: A Study of Factors Contributing to Programme Satisfaction amongst Masters Students

ERIC Educational Resources Information Center

Frumkin, Lara A.; Milankovic-Atkinson, Maya; Sadler, Chris

2007-01-01

Background: Universities have a vested interest in attracting and encouraging enrolment of as many high calibre students as possible. With greater frequency, universities are using marketing techniques to do so. Aims: The study reviewed current student opinions of a programme within a UK university to discover its shortcomings and strengths.…

The Structure of Problem Behavior in a Sample of Maltreated Youths

ERIC Educational Resources Information Center

Culhane, Sara E.; Taussig, Heather N.

2009-01-01

Studies of adolescent community samples suggest that substance use, risky sexual behavior, delinquency, and other problem behaviors can be explained in part by a single, underlying factor or syndrome. Of current interest is the generalizability of these findings to subgroups or special populations of youths who may be at high risk for problem…

BioBridge Professional Development: Bringing Innovative Science into the Classroom

ERIC Educational Resources Information Center

Babendure, Jeremy; Thompson, Loren; Peterman, Karen; Teiper, Leanne; Gastil, Heather; Liwanag, Heather; Glenn-Lee, Shelley

2011-01-01

The BioBridge Professional Development model was created to bring current and relevant science into the high school classroom. The purpose of this intervention was to connect teachers with relevant science and to create innovative, hands-on activities that engage students, with the goal of increasing student interest in STEM careers. To this end,…

Mindfulness-Based Mind Fitness Training: A Case Study of a High-Stress Predeployment Military Cohort

ERIC Educational Resources Information Center

Stanley, Elizabeth A.; Schaldach, John M.; Kiyonaga, Anastasia; Jha, Amishi P.

2011-01-01

Current military deployments have resulted in many psychological and physical health issues and created interest in protective measures to mitigate effects of prolonged and repetitive stress. Mindfulness training has been successfully used for stress reduction in other contexts. The following case report presents a detachment of U.S. Marines who…

High performance mode locking characteristics of single section quantum dash lasers.

PubMed

Rosales, Ricardo; Murdoch, S G; Watts, R T; Merghem, K; Martinez, Anthony; Lelarge, Francois; Accard, Alain; Barry, L P; Ramdane, Abderrahim

2012-04-09

Mode locking features of single section quantum dash based lasers are investigated. Particular interest is given to the static spectral phase profile determining the shape of the mode locked pulses. The phase profile dependence on cavity length and injection current is experimentally evaluated, demonstrating the possibility of efficiently using the wide spectral bandwidth exhibited by these quantum dash structures for the generation of high peak power sub-picosecond pulses with low radio frequency linewidths.

High current densities above 100 K in the high-temperature superconductor HgBa2CaCu2O6+δ

NASA Astrophysics Data System (ADS)

Krusin-Elbaum, L.; Tsuei, C. C.; Gupta, A.

1995-02-01

THE recent discovery1,2 of a family of mercury-based copper oxide superconductors having transition temperatures1-3 above 130 K is of considerable technological interest. But the viability of high-temperature superconductors for many applications will ultimately depend on the size of the current density, Jc, that they are able to support, not only at high temperatures, but also in high magnetic fields. For the cuprate superconductors, and in particular for Hg-based materials, the combination of high transition temperature1-3 and large mass anisotropy implies that the transport properties will be intrinsically limited by large thermal fluctuations and short superconducting coherence lengths4. Here we report that high-quality c-axis-oriented epitaxial films of the compound HgBa2CaCu6O6+δ (Hg-1212; ref. 5) can support large in-plane current densities at temperatures higher than has been achieved for other superconductors. In low magnetic fields oriented normal to the film surface, we find Jc>~107 A cm-2 at 5 K and Jc~ 105 A cm-2 at 110 K, at least an order of magnitude larger than for Bi- or Tl-based films6-11. For in-plane magnetic fields, the critical current (~108 A cm-2) is close to the theoretical limit even at high fields, indicative of strong intrinsic pinning in this compound.

Targeting the human genome-microbiome axis for drug discovery: inspirations from global systems biology and traditional Chinese medicine.

PubMed

Zhao, Liping; Nicholson, Jeremy K; Lu, Aiping; Wang, Zhengtao; Tang, Huiru; Holmes, Elaine; Shen, Jian; Zhang, Xu; Li, Jia V; Lindon, John C

2012-07-06

Most chronic diseases impairing current human public health involve not only the human genome but also gene-environment interactions, and in the latter case the gut microbiome is an important factor. This makes the classical single drug-receptor target drug discovery paradigm much less applicable. There is widespread and increasing international interest in understanding the properties of traditional Chinese medicines (TCMs) for their potential utilization as a source of new drugs for Western markets as emerging evidence indicates that most TCM drugs are actually targeting both the host and its symbiotic microbes. In this review, we explore the challenges of and opportunities for harmonizing Eastern-Western drug discovery paradigms by focusing on emergent functions at the whole body level of humans as superorganisms. This could lead to new drug candidate compounds for chronic diseases targeting receptors outside the currently accepted "druggable genome" and shed light on current high interest issues in Western medicine such as drug-drug and drug-diet-gut microbial interactions that will be crucial in the development and delivery of future therapeutic regimes optimized for the individual patient.

Minimal Unified Resolution to R_{K^{(*)}} and R(D^{(*)}) Anomalies with Lepton Mixing.

PubMed

Choudhury, Debajyoti; Kundu, Anirban; Mandal, Rusa; Sinha, Rahul

2017-10-13

It is a challenging task to explain, in terms of a simple and compelling new physics scenario, the intriguing discrepancies between the standard model expectations and the data for the neutral-current observables R_{K} and R_{K^{*}}, as well as the charged-current observables R(D) and R(D^{*}). We show that this can be achieved in an effective theory with only two unknown parameters. In addition, this class of models predicts some interesting signatures in the context of both B decays as well as high-energy collisions.

Inferring electric fields and currents from ground magnetometer data - A test with theoretically derived inputs

NASA Technical Reports Server (NTRS)

Wolf, R. A.; Kamide, Y.

1983-01-01

Advanced techniques considered by Kamide et al. (1981) seem to have the potential for providing observation-based high time resolution pictures of the global ionospheric current and electric field patterns for interesting events. However, a reliance on the proposed magnetogram-inversion schemes for the deduction of global ionospheric current and electric field patterns requires proof that reliable results are obtained. 'Theoretical' tests of the accuracy of the magnetogram inversion schemes have, therefore, been considered. The present investigation is concerned with a test, involving the developed KRM algorithm and the Rice Convection Model (RCM). The test was successful in the sense that there was overall agreement between electric fields and currents calculated by the RCM and KRM schemes.

High-order ENO schemes applied to two- and three-dimensional compressible flow

NASA Technical Reports Server (NTRS)

Shu, Chi-Wang; Erlebacher, Gordon; Zang, Thomas A.; Whitaker, David; Osher, Stanley

1991-01-01

High order essentially non-oscillatory (ENO) finite difference schemes are applied to the 2-D and 3-D compressible Euler and Navier-Stokes equations. Practical issues, such as vectorization, efficiency of coding, cost comparison with other numerical methods, and accuracy degeneracy effects, are discussed. Numerical examples are provided which are representative of computational problems of current interest in transition and turbulence physics. These require both nonoscillatory shock capturing and high resolution for detailed structures in the smooth regions and demonstrate the advantage of ENO schemes.

Improvements in Calibration and Analysis of the CTBT-relevant Radioxenon Isotopes with High Resolution SiPIN-based Electron Detectors

NASA Astrophysics Data System (ADS)

Khrustalev, K.

2016-12-01

Current process for the calibration of the beta-gamma detectors used for radioxenon isotope measurements for CTBT purposes is laborious and time consuming. It uses a combination of point sources and gaseous sources resulting in differences between energy and resolution calibrations. The emergence of high resolution SiPIN based electron detectors allows improvements in the calibration and analysis process to be made. Thanks to high electron resolution of SiPIN detectors ( 8-9 keV@129 keV) compared to plastic scintillators ( 35 keV@129keV) there are a lot more CE peaks (from radioxenon and radon progenies) can be resolved and used for energy and resolution calibration in the energy range of the CTBT-relevant radioxenon isotopes. The long term stability of the SiPIN energy calibration allows one to significantly reduce the time of the QC measurements needed for checking the stability of the E/R calibration. The currently used second order polynomials for the E/R calibration fitting are unphysical and shall be replaced by a linear energy calibration for NaI and SiPIN, owing to high linearity and dynamic range of the modern digital DAQ systems, and resolution calibration functions shall be modified to reflect the underlying physical processes. Alternatively, one can completely abandon the use of fitting functions and use only point-values of E/R (similar to the efficiency calibration currently used) at the energies relevant for the isotopes of interest (ROI - Regions Of Interest ). Current analysis considers the detector as a set of single channel analysers, with an established set of coefficients relating the positions of ROIs with the positions of the QC peaks. The analysis of the spectra can be made more robust using peak and background fitting in the ROIs with a single free parameter (peak area) of the potential peaks from the known isotopes and a fixed E/R calibration values set.

Study on the feasibility of provision of distance learning programmes in surgery to Malawi.

PubMed

Mains, Edward A A; Blackmur, James P; Dewhurst, David; Ward, Ross M; Garden, O James; Wigmore, Stephen J

2011-12-01

Medical educational opportunities and resources are considerably limited in the developing world. The expansion of computing and Internet access means that there exists a potential to provide education to students through distance learning programmes. This study investigated the feasibility of providing distance learning course in surgery in Malawi. The study investigated the user requirements, technical requirements and Internet connections in two teaching hospitals in Malawi. In addition the appropriateness of current course material from the Edinburgh Surgical Sciences Qualification to Malawi trainees was assessed. The study found a high degree of interest from Malawian trainees in distance learning. The provision of basic science modules such as anatomy and physiology and the ability to access journals were considered highly desirable. The current ESSQ course would require extensive re-modelling to make it suitable to an African trainee's requirements. Internet speeds remain slow and access is currently expensive. There is considerable interest in distance learning programmes in Malawi but access to them is limited partly because of slow and expensive Internet access. Understanding the needs of trainees in countries such as Malawi will allow better direction of educational aid and resources to support surgical training. Copyright © 2010 Royal College of Surgeons of Edinburgh (Scottish charity number SC005317) and Royal College of Surgeons in Ireland. Published by Elsevier Ltd. All rights reserved.

Modification of polymer velvet cathode via metallic Mo coating for enhancement of high-current electron emission performances

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xiong, Ying; Wang, Bing; Yi, Yong

2013-09-15

The effect of surface Mo coating on the high-current electron emission performances for polymer velvet cathode has been investigated in a diode with A-K gap of 11.5 cm by the combination of time-resolved electrical diagnostic and temporal pressure variation. Compared with uncoated polymer velvet cathode under the single-pulsed emission mode, the Mo-coated one shows lower outgassing levels (∼0.40 Pa L), slower cathode plasma expansion velocity (∼2.30 cm/μs), and higher emission stability as evidences by the change in cathode current, temporal pressure variation, and diode perveance. Moreover, after Mo coating, the emission consistency of the polymer velvet cathode between two adjacentmore » pulses is significantly improved in double-pulsed emission mode with ∼500 ns interval between two pulses, which further confirms the effectiveness of Mo coating for enhancement of electron emission performance of polymer velvet cathodes. These results should be of interest to the high-repetitive high-power microwave systems with cold cathodes.« less

The Roles of Ability, Personality, and Interests in Acquiring Current Events Knowledge: A Longitudinal Study

ERIC Educational Resources Information Center

Hambrick, David Z.; Pink, Jeffrey E.; Meinz, Elizabeth J.; Pettibone, Jonathan C.; Oswald, Frederick L.

2008-01-01

The purpose of this study was to investigate sources of inter-individual differences in current events knowledge. The study occurred in two sessions. In the initial session, 579 participants completed tests to ability, personality, and interest factors, as well as prior knowledge of current events. Approximately 10 weeks later, participants…

Proteins in Ionic Liquids: Current Status of Experiments and Simulations.

PubMed

Schröder, Christian

2017-04-01

In the last two decades, while searching for interesting applications of ionic liquids as potent solvents, their solvation properties and their general impact on biomolecules, and in particular on proteins, gained interest. It turned out that ionic liquids are excellent solvents for protein refolding and crystallization. Biomolecules showed increased solubilities and stabilities, both operational and thermal, in ionic liquids, which also seem to prevent self-aggregation during solubilization. Biomolecules can be immobilized, e.g. in highly viscous ionic liquids, for particular biochemical processes and can be designed to some extent by the proper choice of the ionic liquid cations and anions, which can be characterized by the Hofmeister series.

Atomic-Monolayer Two-Dimensional Lateral Quasi-Heterojunction Bipolar Transistors with Resonant Tunneling Phenomenon.

PubMed

Lin, Che-Yu; Zhu, Xiaodan; Tsai, Shin-Hung; Tsai, Shiao-Po; Lei, Sidong; Shi, Yumeng; Li, Lain-Jong; Huang, Shyh-Jer; Wu, Wen-Fa; Yeh, Wen-Kuan; Su, Yan-Kuin; Wang, Kang L; Lan, Yann-Wen

2017-11-28

High-frequency operation with ultrathin, lightweight, and extremely flexible semiconducting electronics is highly desirable for the development of mobile devices, wearable electronic systems, and defense technologies. In this work, the experimental observation of quasi-heterojunction bipolar transistors utilizing a monolayer of the lateral WSe 2 -MoS 2 junctions as the conducting p-n channel is demonstrated. Both lateral n-p-n and p-n-p heterojunction bipolar transistors are fabricated to exhibit the output characteristics and current gain. A maximum common-emitter current gain of around 3 is obtained in our prototype two-dimensional quasi-heterojunction bipolar transistors. Interestingly, we also observe the negative differential resistance in the electrical characteristics. A potential mechanism is that the negative differential resistance is induced by resonant tunneling phenomenon due to the formation of quantum well under applying high bias voltages. Our results open the door to two-dimensional materials for high-frequency, high-speed, high-density, and flexible electronics.

Evidence from Neurolinguistic Methodologies: Can It Actually Inform Linguistic/Language Acquisition Theories and Translate to Evidence-Based Applications?

ERIC Educational Resources Information Center

Roberts, Leah; González Alonso, Jorge; Pliatsikas, Christos; Rothman, Jason

2018-01-01

This special issue is a testament to the recent burgeoning interest by theoretical linguists, language acquisitionists and teaching practitioners in the neuroscience of language. It offers a highly valuable, state-of-the-art overview of the neurophysiological methods that are currently being applied to questions in the field of second language…

Race to the Top Leaves Children and Future Citizens behind: The Devastating Effects of Centralization, Standardization, and High Stakes Accountability

ERIC Educational Resources Information Center

Onosko, Joe

2011-01-01

President Barack Obama's Race to the Top (RTT) is a profoundly flawed educational reform plan that increases standardization, centralization, and test-based accountability in our nation's schools. Following a brief summary of the interest groups supporting the plan, who is currently participating in this race, why so many states voluntarily…

The Current Status and Future Prospects of Corporate e-Learning in Korea

ERIC Educational Resources Information Center

Lim, Cheolil

2007-01-01

Corporate e-Learning in Korea has grown rapidly over the previous six years (2000-2005). This study argues that the main cause of this heightened interest in corporate e-Learning in Korea was not that companies needed to provide high-quality training programs through the Internet, but rather that the government took initiative to transform the…

Genetic Improvement of Southern hardwoods: The Current Status of Research

Treesearch

Robert E. Farmer

1967-01-01

Genetics research in southern hardwoods has moved, during the past decade, from a minor position in a few organizations to major status in most of the South's forest research establishments. This new interest in hardwood tree improvement has stemmed largely from (1) the increasing use of hardwoods for pulp and (2) a decreasing supply of high-quality hardwood...

Reviewing the Differences in Size, Composition and Structure between the Personal Networks of High-and Low-Performing Students

ERIC Educational Resources Information Center

Casquero, Oskar; Ovelar, Ramón; Romo, Jesús; Benito, Manuel

2015-01-01

An interesting aspect in the current literature about learning networks is the shift of focus from the understanding of the "whole network" of a course to the examination of the "personal networks" of individual students. This line of research is relatively new, based on small-scale studies and diverse analysis techniques,…

Using environmental and site-specific variables to model current and potential distribution of red spruce forest habitat in West Virginia

Treesearch

Nathan Beane; James Rentch

2010-01-01

With the extensive loss of presettlement habitat for red spruce, this species is a high priority for restoration in West Virginia. The advent of climate change caused by human activity and the uncertainty of future environmental changes has also raised interests in the protection and restoration of red spruce ecosystems.

Exploring the Spatial Representativeness of NAAQS and Near Roadway Sites Using High-Spatial Resolution Air Pollution Maps Produced by A Mobile Mapping Platform

EPA Science Inventory

In the current study, three Google Street View cars were equipped with the Aclima Environmental Intelligence ™ Platform. The air pollutants of interest, including O3, NO, NO2, CO2, black carbon, and particle number in several size ranges, were measured using a suite of fast...

Sand and Dust on Mars

NASA Technical Reports Server (NTRS)

Greeley, Ronald; Haberle, Robert M.

1991-01-01

Mars is a planet of high scientific interest. Various studies are currently being made that involve vehicles that have landed on Mars. Because Mars is known to experience frequent wind storms, mission planners and engineers require knowledge of the physical and chemical properties of Martian windblown sand and dust, and the processes involved in the origin and evolution of sand and dust storms.

The Forest Biomass Resource of the United States

Treesearch

Noel D. Cost; James O. Howard; Bert Mead; William H. McWilliams; W. Brad Smith; Dwane D. van Hooser; Eric H. Wharton

1990-01-01

Over the last decade, biomass statistics have been published for most states. However, the existing aggregate data are either limited or out of date. The most recent statistics on biomass were for 1980 (U.S. Department of Agriculture 1981). The development of such data continues to lag even though user interest is high. This study was initiated to provide current...

Welding of High-Strength Steels for Aircraft and Missile Applications

DTIC Science & Technology

1959-10-12

40 PRECIPITATION -HARDENING STAINLESS STEELS ...... .............. .. 40 Single-Treatment Martensitic Steelse ...metal. A survey of the procedures currently being used is presented. Low - Alloy Martensitic Steels AISI 4340, AMS 6434, XZOO, 300M, and 17-Z2AS all are...in roughly decreasing order of industry-wide interest: low - alloy martensitic steels , hot-work die steels , martensitic stainless steels , and

Indiana Wesleyan University SPS Physics Outreach to Rural Middle School and High School Students

NASA Astrophysics Data System (ADS)

Ostrander, Joshua; Rose, Heath; Burchell, Robert; Ramos, Roberto

2013-03-01

The Society of Physics Students chapter at Indiana Wesleyan University is unusual in that it has no physics major, only physics minors. Yet while just over a year old, IWU-SPS has been active in performing physics outreach to middle school and high school students, and the rural community of Grant County. Our year-old SPS chapter consists of majors from Chemistry, Nursing, Biology, Exercise Science, Computer Science, Psychology, Pastoral Studies, and Science Education, who share a common interest in physics and service to the community. IWU currently has a physics minor and is currently working to build a physics major program. Despite the intrinsic challenges, our multi-disciplinary group has been successful at using physics demonstration equipment and hands-on activities and their universal appeal to raise the interest in physics in Grant County. We report our experience, challenges, and successes with physics outreach. We describe in detail our two-pronged approach: raising the level of physics appreciation among the IWU student community and among pre-college students in a rural community of Indiana. Acknowledgements: We acknowledge the support of the Society of Physics Students through a Marsh White Outreach Award and a Blake Lilly Prize.

Tidal current energy potential of Nalón river estuary assessment using a high precision flow model

NASA Astrophysics Data System (ADS)

Badano, Nicolás; Valdés, Rodolfo Espina; Álvarez, Eduardo Álvarez

2018-05-01

Obtaining energy from tide currents in onshore locations is of great interest due to the proximity to the points of consumption. This opens the door to the feasibility of new installations based on hydrokinetic microturbines even in zones of moderate speed. In this context, the accuracy of energy predictions based on hydrodynamic models is of paramount importance. This research presents a high precision methodology based on a multidimensional hydrodynamic model that is used to study the energetic potential in estuaries. Moreover, it is able to estimate the flow variations caused by microturbine installations. The paper also shows the results obtained from the application of the methodology in a study of the Nalón river mouth (Asturias, Spain).

Nonlocality and the critical Reynolds numbers of the minimum state magnetohydrodynamic turbulence

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou Ye; Oughton, Sean

2011-07-15

Magnetohydrodynamic (MHD) systems can be strongly nonlinear (turbulent) when their kinetic and magnetic Reynolds numbers are high, as is the case in many astrophysical and space plasma flows. Unfortunately these high Reynolds numbers are typically much greater than those currently attainable in numerical simulations of MHD turbulence. A natural question to ask is how can researchers be sure that their simulations have reproduced all of the most influential physics of the flows and magnetic fields? In this paper, a metric is defined to indicate whether the necessary physics of interest has been captured. It is found that current computing resourcesmore » will typically not be sufficient to achieve this minimum state metric.« less

Circular Bacteriocins: Biosynthesis and Mode of Action

PubMed Central

Brede, Dag A.; Nes, Ingolf F.; Diep, Dzung B.

2014-01-01

Circular bacteriocins are a group of N-to-C-terminally linked antimicrobial peptides, produced by Gram-positive bacteria of the phylum Firmicutes. Circular bacteriocins generally exhibit broad-spectrum antimicrobial activity, including against common food-borne pathogens, such as Clostridium and Listeria spp. These peptides are further known for their high pH and thermal stability, as well as for resistance to many proteolytic enzymes, properties which make this group of bacteriocins highly promising for potential industrial applications and their biosynthesis of particular interest as a possible model system for the synthesis of highly stable bioactive peptides. In this review, we summarize the current knowledge on this group of bacteriocins, with emphasis on the recent progress in understanding circular bacteriocin genetics, biosynthesis, and mode of action; in addition, we highlight the current challenges and future perspectives for the application of these peptides. PMID:25172850

Expectations of Students about Astronomy in High School

NASA Astrophysics Data System (ADS)

Peixoto, Denis Eduardo; Kleinke, Maurício Urban

2016-12-01

Current literature reports that the astronomy education is motivating and interesting for basic education, but the content suggested by the national curriculum guidelines do not seem to attract students and teachers in order to transcend the discipline of Science in the elementary School or Physics in High School. By applying a questionnaire to 80 students of High School and participants of Brazilian Olympiad of Astronomy and Astronautics of two schools of São Paulo state, we obtained results that indicate that astronomy topics that really motivate students are topics linked to science fiction and current research, which are the subject of extensive media release and have a strong interdisciplinary character. At the end of the work we suggest a new context for astronomy education, by inserting topics combined with other areas of knowledge to what we call “interdisciplinary astrophysics teaching”.

Determining the maximum charging currents of lithium-ion cells for small charge quantities

NASA Astrophysics Data System (ADS)

Grimsmann, F.; Gerbert, T.; Brauchle, F.; Gruhle, A.; Parisi, J.; Knipper, M.

2017-10-01

In order to optimize the operating parameters of battery management systems for electric and hybrid vehicles, great interest has been shown in achieving the maximum permissible charging currents during recuperation, without causing a cell damage due to lithium plating, in relation to the temperature, charge quantity and state of charge. One method for determining these recuperation currents is measuring the cell thickness, where excessively high charging currents can be detected by an irreversible increase in thickness. It is not possible to measure particularly small charge quantities by employing mechanic dial indicators, which have a limited resolution of 1 μm. This is why we developed a measuring setup that has a resolution limit of less than 10 nm using a high-resolution contactless inductance sensor. Our results show that the permissible charging current I can be approximated in relation to the charge quantity x by a correlating function I =a /√{(x) } which is compliant with the Arrhenius law. Small charge quantities therefore have an optimization potential for energy recovery during recuperation.

Community males show multiple-perpetrator rape proclivity: development and preliminary validation of an interest scale.

PubMed

Alleyne, Emma; Gannon, Theresa A; Ó Ciardha, Caoilte; Wood, Jane L

2014-02-01

The literature on Multiple Perpetrator Rape (MPR) is scant; however, a significant proportion of sexual offending involves multiple perpetrators. In addition to the need for research with apprehended offenders of MPR, there is also a need to conduct research with members of the general public. Recent advances in the forensic literature have led to the development of self-report proclivity scales. These scales have enabled researchers to conduct evaluative studies sampling from members of the general public who may be perpetrators of sexual offenses and have remained undetected, or at highest risk of engaging in sexual offending. The current study describes the development and preliminary validation of the Multiple-Perpetrator Rape Interest Scale (M-PRIS), a vignette-based measure assessing community males' sexual arousal to MPR, behavioral propensity toward MPR and enjoyment of MPR. The findings show that the M-PRIS is a reliable measure of community males' sexual interest in MPR with high internal reliability and temporal stability. In a sample of university males we found that a large proportion (66%) did not emphatically reject an interest in MPR. We also found that rape-supportive cognitive distortions, antisocial attitudes, and high-risk sexual fantasies were predictors of sexual interest in MPR. We discuss these findings and the implications for further research employing proclivity measures referencing theory development and clinical practice.

Who Chooses STEM Careers? Using A Relative Cognitive Strength and Interest Model to Predict Careers in Science, Technology, Engineering, and Mathematics.

PubMed

Wang, Ming-Te; Ye, Feifei; Degol, Jessica Lauren

2017-08-01

Career aspirations in science, technology, engineering, and mathematics (STEM) are formulated in adolescence, making the high school years a critical time period for identifying the cognitive and motivational factors that increase the likelihood of future STEM employment. While past research has mainly focused on absolute cognitive ability levels in math and verbal domains, the current study tested whether relative cognitive strengths and interests in math, science, and verbal domains in high school were more accurate predictors of STEM career decisions. Data were drawn from a national longitudinal study in the United States (N = 1762; 48 % female; the first wave during ninth grade and the last wave at age 33). Results revealed that in the high-verbal/high-math/high-science ability group, individuals with higher science task values and lower orientation toward altruism were more likely to select STEM occupations. In the low-verbal/moderate-math/moderate-science ability group, individuals with higher math ability and higher math task values were more likely to select STEM occupations. The findings suggest that youth with asymmetrical cognitive ability profiles are more likely to select careers that utilize their cognitive strengths rather than their weaknesses, while symmetrical cognitive ability profiles may grant youth more flexibility in their options, allowing their interests and values to guide their career decisions.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Giaquinto, Joseph M.; Younkin, James R.

The purpose of this letter report is to document the response for an Expression of Interest (EOI) sent to the European Safeguards and research and development (R&D) scientific communities for the distribution of small amounts of high purity 233U materials for use in safeguards, nonproliferation, and basic R&D in the nuclear disciplines. The intent for the EOI was to gauge the level of international interest for these materials from government and research institutions with programmatic missions in the nuclear security or nuclear R&D arena. The information contained herein is intended to provide information to assist key decision makers in DOEmore » as to the ultimate disposition path for the high purity materials currently being recovered at Oak Ridge National Laboratory (ORNL) and only those items for which there is no United States (U.S.) sponsor identified.« less

Assessment of United States and Japanese Athletic Trainers' Satisfaction with Current Ascension Pathways and Interest in Future Transnational Certification

ERIC Educational Resources Information Center

Presuto, Dax A.

2013-01-01

Background: The purpose of this cross-system and cross-cultural study was to investigate the current athletic training systems in the US and Japan, to assess US and Japanese athletic trainers' satisfaction with current athletic training ascension pathways in their respective country and to determine their interest in future transnational…

Harm reduction and cessation efforts and interest in cessation resources among survivors of smoking-related cancers

PubMed Central

Berg, Carla J.; Carpenter, Matthew J.; Jardin, Bianca; Ostroff, Jamie S.

2013-01-01

Purpose Despite the well-established risks associated with persistent smoking, many cancer survivors who were active smokers at the time of cancer diagnosis continue to smoke. In order to guide the development of tobacco cessation interventions for cancer survivors, a better understanding is needed regarding post-diagnosis quitting efforts. Thus, we examined quitting and reduction efforts and interest in cessation resources among cancer survivors who self-identified as current smokers at the time of diagnosis. Methods We conducted analyses of survey participants (n=54) who were current smokers at the time of cancer diagnosis and were continued smokers at the time of assessment. We also conducted semi-structured interviews (n=21) among a subset of those who either continued to smoke or quit smoking post cancer diagnosis. Results Among our survey participants, 22.2% had ever used behavioral cessation resources and 66.7% had use pharmacotherapy, while 62.8% had interest in future use of behavioral cessation resources and 75.0% had interest in pharmacotherapy. The majority reported some quitting efforts including making quit attempts, using cessation medications, and reducing their daily cigarette consumption. Semi-structured interview data revealed various strategies used to aid in smoking reduction and cessation as well as variability in preferences for cessation resources. Conclusions Cancer patients who smoke following diagnosis often engage in smoking reduction and cessation-related behaviors, which may reflect their motivation to reduce their smoking-related risks. They also report high interest in cessation resources. Thus, it is important to explore the acceptability and effectiveness of different cessation intervention components among this group. PMID:23307036

Cigarette Smoking and Interest in Quitting Among Overweight and Obese Adults with Serious Mental Illness Enrolled in a Fitness Intervention

PubMed Central

Aschbrenner, Kelly A.; Brunette, Mary F.; McElvery, Raleigh; Naslund, John A.; Scherer, Emily; Pratt, Sarah I.; Bartels, Stephen J.

2016-01-01

This study explored cigarette smoking, health status, and interest in quitting among overweight and obese adults with serious mental illness enrolled in a fitness intervention. Baseline data from two studies of the In SHAPE fitness intervention were combined. A total of 341 overweight or obese adults with serious mental illness were assessed on smoking, interest in quitting, cardiovascular fitness, lipids, body mass index, readiness to change diet, and psychiatric symptoms. Thirty-six percent (n=122) of participants were categorized as current smokers. The majority of smokers (84%) were interested in quitting. Smokers were more likely to be younger, male, and less educated than non-smokers. Smokers had lower high-density lipoprotein cholesterol and were less ready to reduce dietary fat, after adjusting for age, gender, and education. Findings highlight the potential to address both fitness and smoking in order to reduce cardiovascular risk in individuals with serious mental illness. PMID:26034872

Benefits of Enterprise Social Networking Systems for High Energy Physics community

NASA Astrophysics Data System (ADS)

Silva de Sousa, B.; Wagner, A.; Ormancey, E.; Grzywaczewski, P.

2015-12-01

The emergence of social media platforms in the consumer space unlocked new ways of interaction between individuals on the Web. People develop now their social networks and relations based on common interests and activities with the choice to opt-in or opt-out on content of their interest. This kind of platforms have also an important place to fill inside large organizations and enterprises where communication and collaborators interaction are keys for development. Enterprise Social Networking Systems (ESN) add value to an organization by encouraging information sharing, capturing knowledge, enabling action and empowering people. CERN is currently rolling out an ESN which aims to unify and provide a single point of access to the multitude of information sources in the organization. It also implements social features that can be added on top of existing communication channels. While the deployment of this kind of platforms is not without risks we firmly believe that they are of the best interest for our community, opening the opportunity to evaluate a global social network for High Energy Physics (HEP).

Vertically stacked multi-heterostructures of layered materials for logic transistors and complementary inverters

PubMed Central

Yu, Woo Jong; Li, Zheng; Zhou, Hailong; Chen, Yu; Wang, Yang; Huang, Yu; Duan, Xiangfeng

2014-01-01

The layered materials such as graphene have attracted considerable interest for future electronics. Here we report the vertical integration of multi-heterostructures of layered materials to enable high current density vertical field-effect transistors (VFETs). An n-channel VFET is created by sandwiching few-layer molybdenum disulfide (MoS2) as the semiconducting channel between a monolayer graphene and a metal thin film. The VFETs exhibit a room temperature on-off ratio >103, while at same time deliver a high current density up to 5,000 A/cm2, sufficient for high performance logic applications. This study offers a general strategy for the vertical integration of various layered materials to obtain both p- and n-channel transistors for complementary logic functions. A complementary inverter with larger than unit voltage gain is demonstrated by vertically stacking the layered materials of graphene, Bi2Sr2Co2O8 (p-channel), graphene, MoS2 (n-channel), and metal thin film in sequence. The ability to simultaneously achieve high on-off ratio, high current density, and logic integration in the vertically stacked multi-heterostructures can open up a new dimension for future electronics to enable three-dimensional integration. PMID:23241535

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jordanova, Vania K

Understanding the response at Earth of the Sun's varying energy output and forecasting geomagnetic activity is of central interest to space science, since intense geomagnetic storms may cause severe damages on technological systems and affect communications. Episodes of southward (Bz

Electrochemical characterization of high frequency stimulation electrodes: role of electrode material and stimulation parameters on electrode polarization

NASA Astrophysics Data System (ADS)

Ghazavi, Atefeh; Cogan, Stuart F.

2018-06-01

Objective. With recent interest in kilohertz frequency electrical stimulation for nerve conduction block, understanding the electrochemistry and role of electrode material is important for assessing the safety of these stimulus protocols. Here we describe an approach to determining electrode polarization in response to continuous kilohertz frequency sinusoidal current waveforms. We have also investigated platinum, iridium oxide, and titanium nitride as coatings for high frequency electrodes. The current density distribution at 50 kHz at the electrode–electrolyte interface was also modeled to demonstrate the importance of the primary current distribution in supporting charge injection at high frequencies. Approach. We determined electrode polarization in response to sinusoidal currents with frequencies in the 1–50 kHz range and current amplitudes from 100 to 500 µA and 1–5 mA, depending on the electrode area. The current density distribution at the interface was modeled using the finite element method (FEM). Main results. At low frequencies, 1–5 kHz, polarization on the platinum electrode was significant, exceeding the water oxidation potential for high amplitude (5 mA) waveforms. At frequencies of 20 kHz or higher, the polarization was less than 300 mV from the electrode open circuit potential. The choice of electrode material did not play a significant role in electrode polarization at frequencies higher than 10 kHz. The current density distribution modeled at 50 kHz is non-uniform and this non-uniformity persists throughout charge delivery. Significance. At high frequencies (>10 kHz) electrode double-layer charging is the principal mechanism of charge-injection and selection of the electrode material has little effect on polarization, with platinum, iridium oxide, and titanium nitride exhibiting similar behavior. High frequency stimulation is dominated by a highly nonuniform primary current distribution.

The relationship between challenging behaviours, mood and interest/pleasure in adults with severe and profound intellectual disabilities.

PubMed

Bernstein, A M; Visconti, K J; Csorba, J; Radvanyi, K; Rojahn, J

2015-11-01

We investigated whether current mood and interest/pleasure ratings in adults with moderate to profound intellectual disabilities were predictive of challenging behaviour [self-injurious behaviour (SIB), aggressive/destructive behaviour and stereotypic behaviour] and vice versa. In this combined cross-sectional and longitudinal study, staff members of a Hungarian residential facility completed translated versions of the Behaviour Problems Inventory-Short Form (BPI-S), the Challenging Behaviour Interview (CBI) and the Mood, Interest and Pleasure Questionnaire-Short Form (MIPQ-S) for 50 participants at two time points, approximately 4 to 5 months apart. Bivariate correlations from data concurrently assessed at Time-1 showed significant linear relationships between the SIB (both frequency and severity scores) and Interest/Pleasure sub-scales, and the Aggressive/Destructive Behaviour (severity scores) and the MIPQ-S Mood sub-scales (unadjusted for multiple correlations). All of these effects were found with the BPI-S data, but not with the CBI. Multiple regression analyses revealed that (1) low interest/pleasure assessed at Time-1 predicted high SIB (frequency and severity) at Time-2. (2) Interest/pleasure was not predictive of aggressive or stereotypic behaviour. (3) Mood at Time-1 did not predict any of the three types of behaviour problems at Time-2. (4) In reverse, high SIB (frequency and severity) at Time-1 predicted low interest/pleasure ratings at Time-2. (5) Surprisingly, frequent aggressive/destructive behaviour predicted high interest/pleasure. (6) Stereotypic behaviour scores at Time-1 did not predict interest/pleasure ratings at Time-2. Again, all of these effects were only found with the BPI-S data, but not with the CBI. Internal consistency, test-retest reliability and concurrent validity of the Hungarian versions of all three questionnaires had generally satisfactory outcomes. The fact that increasingly frequent and severe SIB was predicted by declining measures of interest/pleasure is consistent with previous studies. Contrary to those earlier studies, however, we found that SIB was not predicted by mood and that aggressive/destructive behaviour actually predicted future elevated mood. Implications for future research regarding the directional relationship between affective states such as mood and interest and pleasure, on the one hand, and challenging behaviour, on the other, were discussed. © 2015 MENCAP and International Association of the Scientific Study of Intellectual and Developmental Disabilities and John Wiley & Sons Ltd.

Developing Tools and Techniques to Increase Communication Effectiveness

NASA Technical Reports Server (NTRS)

Hayes, Linda A.; Peterson, Doug

1997-01-01

The Public Affairs Office (PAO) of the Johnson Space Center (JSC) is responsible for communicating current JSC Space Program activities as well as goals and objectives to the American Public. As part of the 1996 Strategic Communications Plan, a review of PAO' s current communication procedures was conducted. The 1996 Summer Faculty Fellow performed research activities to support this effort by reviewing current research concerning NASA/JSC's customers' perceptions and interests, developing communications tools which enable PAO to more effectively inform JSC customers about the Space Program, and proposing a process for developing and using consistent messages throughout PAO. Note that this research does not attempt to change or influence customer perceptions or interests but, instead, incorporates current customer interests into PAO's communication process.

12 CFR 602.10 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... information for a use or purpose that furthers the commercial, trade, or profit interests of that individual... higher education, an institution of professional education, or an institution of vocational education... means information about current events or of current interest to the public. Reproduce (or reproduction...

Semi-Supervised Novelty Detection with Adaptive Eigenbases, and Application to Radio Transients

NASA Technical Reports Server (NTRS)

Thompson, David R.; Majid, Walid A.; Reed, Colorado J.; Wagstaff, Kiri L.

2011-01-01

We present a semi-supervised online method for novelty detection and evaluate its performance for radio astronomy time series data. Our approach uses adaptive eigenbases to combine 1) prior knowledge about uninteresting signals with 2) online estimation of the current data properties to enable highly sensitive and precise detection of novel signals. We apply the method to the problem of detecting fast transient radio anomalies and compare it to current alternative algorithms. Tests based on observations from the Parkes Multibeam Survey show both effective detection of interesting rare events and robustness to known false alarm anomalies.

Growth and innovation in medical devices: a conversation with Stryker chairman John Brown. Interview by Lawton R. Burns.

PubMed

Brown, John

2007-01-01

John Brown, current chairman and past chief executive officer (CEO) of the Stryker Corporation, reviews the development of his device firm and the medical device industry over the past thirty years. Brown describes the trajectory of innovation in medical devices and the managerial and organizational strategy he pioneered at Stryker to achieve consistently high growth rates over the long term. He also shares his perspective on some of the current policy issues facing the device industry today, including product safety, conflicts of interest, rising product prices, and direct-to-consumer advertising.

Performance of gigabit FDDI

NASA Technical Reports Server (NTRS)

Game, David; Maly, Kurt J.

1990-01-01

Great interest exists in developing high speed protocols which will be able to support data rates at gigabit speeds. Hardware currently exists which can experimentally transmit at data rates exceeding a gigabit per second, but it is not clear as to what types of protocols will provide the best performance. One possibility is to examine current protocols and their extensibility to these speeds. Scaling of Fiber Distributed Data Interface (FDDI) to gigabit speeds is studied. More specifically, delay statistics are included to provide insight as to which parameters (network length, packet length or number of nodes) have the greatest effect on performance.

Update on diagnosis and treatment of idiopathic pulmonary fibrosis

PubMed Central

Baddini-Martinez, José; Baldi, Bruno Guedes; da Costa, Cláudia Henrique; Jezler, Sérgio; Lima, Mariana Silva; Rufino, Rogério

2015-01-01

Idiopathic pulmonary fibrosis is a type of chronic fibrosing interstitial pneumonia, of unknown etiology, which is associated with a progressive decrease in pulmonary function and with high mortality rates. Interest in and knowledge of this disorder have grown substantially in recent years. In this review article, we broadly discuss distinct aspects related to the diagnosis and treatment of idiopathic pulmonary fibrosis. We list the current diagnostic criteria and describe the therapeutic approaches currently available, symptomatic treatments, the action of new drugs that are effective in slowing the decline in pulmonary function, and indications for lung transplantation. PMID:26578138

Electrically tunable transport and high-frequency dynamics in antiferromagnetic S r3I r2O7

NASA Astrophysics Data System (ADS)

Seinige, Heidi; Williamson, Morgan; Shen, Shida; Wang, Cheng; Cao, Gang; Zhou, Jianshi; Goodenough, John B.; Tsoi, Maxim

2016-12-01

We report dc and high-frequency transport properties of antiferromagnetic S r3I r2O7 . Temperature-dependent resistivity measurements show that the activation energy of this material can be tuned by an applied dc electrical bias. The latter allows for continuous variations in the sample resistivity of as much as 50% followed by a reversible resistive switching at higher biases. Such a switching is of high interest for antiferromagnetic applications in high-speed memory devices. Interestingly, we found the switching behavior to be strongly affected by a high-frequency (microwave) current applied to the sample. The microwaves at 3-7 GHz suppress the dc switching and produce resonancelike features that we tentatively associated with the dissipationless magnonics recently predicted to occur in antiferromagnetic insulators subject to ac electric fields. We have characterized the effects of microwave irradiation on electronic transport in S r3I r2O7 as a function of microwave frequency and power, strength and direction of external magnetic field, strength and polarity of applied dc bias, and temperature. Our observations support the potential of antiferromagnetic materials for high-speed/high-frequency spintronic applications.

Recent Progress on High-Current SRF Cavities at Jlab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert Rimmer, William Clemens, James Henry, Peter Kneisel, Kurt Macha, Frank Marhauser, Larry Turlington, Haipeng Wang, Daniel Forehand

2010-05-01

JLab has designed and fabricated several prototype SRF cavities with cell shapes optimized for high current beams and with strong damping of unwanted higher order modes. We report on the latest test results of these cavities and on developments of concepts for new variants optimized for particular applications such as light sources and high-power proton accelerators, including betas less than one. We also report on progress towards a first beam test of this design in the recirculation loop of the JLab ERL based FEL. With growing interest worldwide in applications of SRF for high-average power electron and hadron machines, amore » practical test of these concepts is highly desirable. We plan to package two prototype cavities in a de-mountable cryomodule for temporary installation into the JLab FEL for testing with RF and beam. This will allow verification of all critical design and operational parameters paving the way to a full-scale prototype cryomodule.« less

Liquid Hydrocarbon Production from CO2 : Recent Development in Metal-Based Electrocatalysis.

PubMed

Daiyan, Rahman; Lu, Xunyu; Ng, Yun Hau; Amal, Rose

2017-11-23

Rising levels of CO 2 accumulation in the atmosphere have attracted considerable interest in technologies capable of CO 2 capture, storage and conversion. The electrochemical reduction of CO 2 into high-value liquid organic products could be of vital importance to mitigate this issue. The conversion of CO 2 into liquid fuels by using photovoltaic cells, which can readily be integrated in the current infrastructure, will help realize the creation of a sustainable cycle of carbon-based fuel that will promote zero net CO 2 emissions. Despite promising findings, significant challenges still persist that must be circumvented to make the technology profitable for large-scale utilization. With such possibilities, this Minireview presents the current high-performing catalysts for the electrochemical reduction of CO 2 to liquid hydrocarbons, address the limitations and unify the current understanding of the different reaction mechanisms. The Minireview also explores current research directions to improve process efficiencies and production rate and discusses the scope of using photo-assisted electrochemical reduction systems to find stable, highly efficient catalysts that can harvest solar energy directly to convert CO 2 into liquid hydrocarbons. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Characterization and growth of epitaxial layers of Gs exhibiting high resistivity for ionic implantation

NASA Technical Reports Server (NTRS)

1979-01-01

Either classical or low temperature epitaxial growth techniques can be used to control the deposition of buffer layers of GaAs on semiconducting substrates and to obtain the resistivity and purity desired. Techniques developed to study, as a function of thickness, the evolution of mobilities by photoHall, and the spectroscopy of shallow and deep centers by cathodoluminescence and current transients reveal one very pure layer of medium resistivity and high mobility, and another "dead layer" of elevated resistivity far from the surface. The highly resistive layer remains pure over several microns, which appears interesting for implantation.

Molecularly imprinted polymers for sample preparation and biosensing in food analysis: Progress and perspectives.

PubMed

Ashley, Jon; Shahbazi, Mohammad-Ali; Kant, Krishna; Chidambara, Vinayaka Aaydha; Wolff, Anders; Bang, Dang Duong; Sun, Yi

2017-05-15

Molecularly imprinted polymers (MIPs) are biomimetics which can selectively bind to analytes of interest. One of the most interesting areas where MIPs have shown the biggest potential is food analysis. MIPs have found use as sorbents in sample preparation attributed to the high selectivity and high loading capacity. MIPs have been intensively employed in classical solid-phase extraction and solid-phase microextraction. More recently, MIPs have been combined with magnetic bead extraction, which greatly simplifies sample handling procedures. Studies have consistently shown that MIPs can effectively minimize complex food matrix effects, and improve recoveries and detection limits. In addition to sample preparation, MIPs have also been viewed as promising alternatives to bio-receptors due to the inherent molecular recognition abilities and the high stability in harsh chemical and physical conditions. MIPs have been utilized as receptors in biosensing platforms such as electrochemical, optical and mass biosensors to detect various analytes in food. In this review, we will discuss the current state-of-the-art of MIP synthesis and applications in the context of food analysis. We will highlight the imprinting methods which are applicable for imprinting food templates, summarize the recent progress in using MIPs for preparing and analysing food samples, and discuss the current limitations in the commercialisation of MIPs technology. Finally, future perspectives will be given. Copyright © 2017 Elsevier B.V. All rights reserved.

Is News Media Related to Civic Engagement? The Effects of Interest in and Discussions about the News Media on Current and Future Civic Engagement of Adolescents

ERIC Educational Resources Information Center

Erentaite, Rasa; Zukauskiene, Rita; Beyers, Wim; Pilkauskaite-Valickiene, Rasa

2012-01-01

This study explored whether discussions about the media, when positively linked to interest in the news media, were related to adolescents' current and future civic engagement. A sample of 2638 adolescents (age M = 17, SD = 1.2), who participated in a school-based study on positive socialization, completed self-report measures on interest in the…

Plato's "Meno" as Form and as Content of Secondary School Courses in Philosophy. An Occasional Paper [And] Plato's "Republic": A Study Guide.

ERIC Educational Resources Information Center

Brumbaugh, Robert; Soderlind, Karen

The document presents two papers related to philosophy instruction at the high school level. The first paper suggests how to motivate beginning philosophy students by injecting a sense of reality and relevance into class discussions. One recommendation for furthering this sense of reality is to ask questions of current interest such as whether…

Men Considering (and Choosing) Teaching as a Career: What Accounts for Their Decision to Become a Teacher?

ERIC Educational Resources Information Center

Keck Frei, Andrea; Berweger, Simone; Bieri Buschor, Christine

2017-01-01

The aim of the current study is to better understand the decision-making of men considering teaching as a career option. By means of a longitudinal study (n = 226), we examined the persistence of male academic high-school students in Switzerland interested in teaching during transition to higher education. For 85 men attending information events…

East Europe Report, Economic and Industrial Affairs

DTIC Science & Technology

1984-08-27

produced at our provincial level turkey broilers consti- tute 50 percent, chickens 40, geese and ducks 10 percent. 45 In addition to the three...opinion. Health care, nutrition , and physical condition, which increase interest in mass sports activities and recreation, are currently becoming such...in years with normal precipitation, the demand for water in regions with high population density and heavy industrialization exceeds the natural

Thomson scattering for core plasma on DEMO

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mukhin, E. E.; Kurskiev, G. S.; Tolstyakov, S. Yu.

2014-08-21

This paper describes the challenges of Thomson scattering implementation for core plasma on DEMO and evaluates the capability to measure extremely high electron temperature range 0.5-40keV. A number of solutions to be developed for ITER diagnostics are suggested in consideration of their realization for DEMO. New approaches suggested for DEMO may also be of interest to ITER and currently operating magnetic confinement devices.

Eye Gaze During Face Processing in Children and Adolescents with 22q11.2 Deletion Syndrome

ERIC Educational Resources Information Center

Glaser, Bronwyn; Debbane, Martin; Ottet, Marie-Christine; Vuilleumier, Patrik; Zesiger, Pascal; Antonarakis, Stylianos E.; Eliez, Stephan

2010-01-01

Objective: The 22q11.2 deletion syndrome (22q11DS) is a neurogenetic syndrome with high risk for the development of psychiatric disorder. There is interest in identifying reliable markers for measuring and monitoring socio-emotional impairments in 22q11DS during development. The current study investigated eye gaze as a potential marker during a…

The study of electrical conductivity of DNA molecules by scanning tunneling spectroscopy

NASA Astrophysics Data System (ADS)

Sharipov, T. I.; Bakhtizin, R. Z.

2017-10-01

An interest to the processes of charge transport in DNA molecules is very high, due to perspective of their using in nanoelectronics. The original sample preparation for studying electrical conductivity of DNA molecules by scanning tunneling spectroscopy has been proposed and tested. The DNA molecules immobilized on gold surface have been imaged clearly and their current-voltage curves have been measured.

An Updated Process for Automated Deepspace Conjunction Assessment

NASA Technical Reports Server (NTRS)

Tarzi, Zahi B.; Berry, David S.; Roncoli, Ralph B.

2015-01-01

There is currently a high level of interest in the areas of conjunction assessment and collision avoidance from organizations conducting space operations. Current conjunction assessment activity is mainly focused on spacecraft and debris in the Earth orbital environment [1]. However, collisions are possible in other orbital environments as well [2]. This paper will focus on the current operations of and recent updates to the Multimission Automated Deep Space Conjunction Assessment Process (MADCAP) used at the Jet Propulsion Laboratory for NASA to perform conjunction assessment at Mars and the Moon. Various space agencies have satellites in orbit at Mars and the Moon with additional future missions planned. The consequences of collisions are catastrophically high. Intuitive notions predict low probability of collisions in these sparsely populated environments, but may be inaccurate due to several factors. Orbits of scientific interest often tend to have similar characteristics as do the orbits of spacecraft that provide a communications relay for surface missions. The MADCAP process is controlled by an automated scheduler which initializes analysis based on a set timetable or the appearance of new ephemeris files either locally or on the Deep Space Network (DSN) Portal. The process then generates and communicates reports which are used to facilitate collision avoidance decisions. The paper also describes the operational experience and utilization of the automated tool during periods of high activity and interest such as: the close approaches of NASA's Lunar Atmosphere & Dust Environment Explorer (LADEE) and Lunar Reconnaissance Orbiter (LRO) during the LADEE mission. In addition, special consideration was required for the treatment of missions with rapidly varying orbits and less reliable long term downtrack estimates; in particular this was necessitated by perturbations to MAVEN's orbit induced by the Martian atmosphere. The application of special techniques to non-operational spacecraft with large uncertainties is also studied. Areas for future work are also described. Although the applications discussed in this paper are in the Martian and Lunar environments, the techniques are not unique to these bodies and could be applied to other orbital environments.

Current Events in Basic Business Education

ERIC Educational Resources Information Center

Van Hook, Barry L.

1974-01-01

The author suggests the use of current events to stimulate student interest in basic business courses. Suggested topics described are monetary devaluation, interest rate adjustments, Illinois no-fault automobile insurance, labor-management disputes, Dow-Jones average, Picasso's death, energy crisis, sale of surplus wheat, local consumer assistance…

Intelligence and EEG current density using low-resolution electromagnetic tomography (LORETA).

PubMed

Thatcher, R W; North, D; Biver, C

2007-02-01

The purpose of this study was to compare EEG current source densities in high IQ subjects vs. low IQ subjects. Resting eyes closed EEG was recorded from 19 scalp locations with a linked ears reference from 442 subjects ages 5 to 52 years. The Wechsler Intelligence Test was administered and subjects were divided into low IQ (< or =90), middle IQ (>90 to <120) and high IQ (> or =120) groups. Low-resolution electromagnetic tomographic current densities (LORETA) from 2,394 cortical gray matter voxels were computed from 1-30 Hz based on each subject's EEG. Differences in current densities using t tests, multivariate analyses of covariance, and regression analyses were used to evaluate the relationships between IQ and current density in Brodmann area groupings of cortical gray matter voxels. Frontal, temporal, parietal, and occipital regions of interest (ROIs) consistently exhibited a direct relationship between LORETA current density and IQ. Maximal t test differences were present at 4 Hz, 9 Hz, 13 Hz, 18 Hz, and 30 Hz with different anatomical regions showing different maxima. Linear regression fits from low to high IQ groups were statistically significant (P < 0.0001). Intelligence is directly related to a general level of arousal and to the synchrony of neural populations driven by thalamo-cortical resonances. A traveling frame model of sequential microstates is hypothesized to explain the results.

Field-aligned current and auroral Hall current characteristics derived from the Swarm constellation

NASA Astrophysics Data System (ADS)

Huang, Tao; Wang, Hui; Hermann, Luehr

2017-04-01

On the basis of field-aligned currents (FACs) and Hall currents derived from high-resolution magnetic field data of the Swarm constellation the average characteristics of these two current systems in the auroral regions are comprehensively investigated by statistical methods. This is the first study considering both current types simultaneously and for both hemispheres. The FAC distribution, derived from the Swarm dual-spacecraft approach, reveals the well-known features of Region 1 (R1) and Region 2 (R2) FACs. At high latitudes, Region 0 (R0) FACs appear on the dayside. Their direction depends on the orientation of the interplanetary magnetic field (IMF) By component. Of particular interest is the distribution of auroral Hall currents. The most prominent auroral electrojets are found to be closely controlled by the solar wind input. But there is no dependence on the IMF By orientation. The eastward electrojet is about twice as strong in summer as in winter. Conversely, the westward electrojet shows less dependence on season. Part of the electrojet current is closed over the polar cap. Here the seasonal variation of conductivity mainly controls the current density. There is a clear channeling of return currents over the polar cap. Depending on IMF By orientation most of the current is flowing either on the dawn or dusk side. The direction of Hall currents in the noon sector depends directly on the orientation of the IMF By. This is true for both signs of the IMF Bz component. But largest differences between summer and winter seasons are found for northward IMF Bz. Around the midnight sector the westward substorm electrojet is dominating. As expected, it is highly dependent on magnetic activity, but shows only little response to the IMF By polarity.

What do we really know about conflicts of interest in biomedical research?

PubMed

Warner, Teddy D; Gluck, John P

2003-12-01

Conflicts of interest in research have long been seen to pose serious threats to the integrity of research. Indeed, the past two decades have revealed increased attention to the possible influence of conflicts of interest as the number of research studies funded by private industry have increased. We review empirical findings directly pertinent to issues concerning financial conflicts of interest in biomedical research, and we provide an overview of the current issues and state of understanding concerning such conflicts in research. We searched Medline from January 1992 to January 2002 to locate current studies that have reported primary or secondary empirical data pertaining to conflicts of interest in research. The rate of potential conflicts of interest for researchers appears to be at least 30% in some situations although the accuracy of such a rate is untested, and the rate of disclosure of conflicts of interest is as low as 2%. Furthermore, some evidence exists to indicate that researchers with conflicting interests may indeed offer different professional opinions and judgments than those for whom such conflicts do not exist. The effectiveness of various disclosure and management methods for conflicts of interest is unknown. We summarize the current empirical literature, concluding that relatively little is known based on such data. We suggest a number of questions that need to be answered by future research, and we offer recommendations for policy makers to consider and evaluate in the future in identifying, revealing, and managing conflicts of interest.

Web-Based Visual Analytics for Social Media

DOE Office of Scientific and Technical Information (OSTI.GOV)

Best, Daniel M.; Bruce, Joseph R.; Dowson, Scott T.

Social media provides a rich source of data that reflects current trends and public opinion on a multitude of topics. The data can be harvested from Twitter, Facebook, Blogs, and other social applications. The high rate of adoption of social media has created a domain that has an ever expanding volume of data that make it difficult to use the raw data for analysis. Information visual analytics is key in drawing out features of interest in social media. The Scalable Reasoning System is an application that couples a back end server performing analysis algorithms and an intuitive front end visualizationmore » to allow for investigation. We provide a componentized system that can be rapidly adapted to customer needs such that the information they are most interested in is brought to their attention through the application. To this end, we have developed a social media application for use by emergency operations for the city of Seattle to show current weather and traffic trends which is important for their tasks.« less

Current Research on Non-Coding Ribonucleic Acid (RNA).

PubMed

Wang, Jing; Samuels, David C; Zhao, Shilin; Xiang, Yu; Zhao, Ying-Yong; Guo, Yan

2017-12-05

Non-coding ribonucleic acid (RNA) has without a doubt captured the interest of biomedical researchers. The ability to screen the entire human genome with high-throughput sequencing technology has greatly enhanced the identification, annotation and prediction of the functionality of non-coding RNAs. In this review, we discuss the current landscape of non-coding RNA research and quantitative analysis. Non-coding RNA will be categorized into two major groups by size: long non-coding RNAs and small RNAs. In long non-coding RNA, we discuss regular long non-coding RNA, pseudogenes and circular RNA. In small RNA, we discuss miRNA, transfer RNA, piwi-interacting RNA, small nucleolar RNA, small nuclear RNA, Y RNA, single recognition particle RNA, and 7SK RNA. We elaborate on the origin, detection method, and potential association with disease, putative functional mechanisms, and public resources for these non-coding RNAs. We aim to provide readers with a complete overview of non-coding RNAs and incite additional interest in non-coding RNA research.

Joint Labeling Of Multiple Regions of Interest (Rois) By Enhanced Auto Context Models.

PubMed

Kim, Minjeong; Wu, Guorong; Guo, Yanrong; Shen, Dinggang

2015-04-01

Accurate segmentation of a set of regions of interest (ROIs) in the brain images is a key step in many neuroscience studies. Due to the complexity of image patterns, many learning-based segmentation methods have been proposed, including auto context model (ACM) that can capture high-level contextual information for guiding segmentation. However, since current ACM can only handle one ROI at a time, neighboring ROIs have to be labeled separately with different ACMs that are trained independently without communicating each other. To address this, we enhance the current single-ROI learning ACM to multi-ROI learning ACM for joint labeling of multiple neighboring ROIs (called e ACM). First, we extend current independently-trained single-ROI ACMs to a set of jointly-trained cross-ROI ACMs, by simultaneous training of ACMs for all spatially-connected ROIs to let them to share their respective intermediate outputs for coordinated labeling of each image point. Then, the context features in each ACM can capture the cross-ROI dependence information from the outputs of other ACMs that are designed for neighboring ROIs. Second, we upgrade the output labeling map of each ACM with the multi-scale representation, thus both local and global context information can be effectively used to increase the robustness in characterizing geometric relationship among neighboring ROIs. Third, we integrate ACM into a multi-atlases segmentation paradigm, for encompassing high variations among subjects. Experiments on LONI LPBA40 dataset show much better performance by our e ACM, compared to the conventional ACM.

DE 1 observations of theta aurora plasma source regions and Birkeland current charge carriers

NASA Technical Reports Server (NTRS)

Menietti, J. D.; Burch, J. L.

1987-01-01

Detailed analyses of the DE 1 high-altitude plasma instrument electron and ion data have been performed for four passes during which theta auroras were observed. The data indicate that the theta auroras occur on what appear to be closed field lines with particle signatures and plasma parameters that are quite similar to those of the magnetospheric boundary plasma sheet. The field-aligned currents computed from particle fluxes in the energy range 18-13 keV above the theta auroras are observed to be generally downward on the dawnside of the arcs with a narrower region of larger (higher density) upward currents on the duskside of the arcs. These currents are carried predominantly by field-aligned beams of accelerated cold electrons. Of particualr interest in regions of upward field-aligned current are downward electron beams at energies less than the inferred potential drop above the spacecraft.

[Practical considerations for high resolution anoscopy in patients infected with human immunodeficiency virus].

PubMed

Iribarren-Díaz, Mauricio; Ocampo Hermida, Antonio; González-Carreró Fojón, Joaquín; Alonso-Parada, María; Rodríguez-Girondo, Mar

2014-12-01

Anal cancer is uncommon in the general population, however its incidence is increasing significantly in certain risk groups, mainly in men who have sex with men, and particularly those infected with human immunodeficiency virus. High resolution anoscopy technique is currently considered the standard in the diagnosis of anal intraepithelial neoplasia, but at present there is no agreed standard method between health areas. High resolution anoscopy is an affordable technique that can be critical in the screening of anal carcinoma and its precursor lesions, but is not without difficulties. We are currently studying the most effective strategy for managing premalignant anal lesions, and with this article we attempt to encourage other groups interested in reducing the incidence of an increasing neoplasia. Copyright © 2013 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

40 CFR 35.6340 - Disposal of CERCLA-funded property.

Code of Federal Regulations, 2014 CFR

2014-07-01

... ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for Superfund... Substance Superfund for EPA's vested interest in the current fair market value of the equipment at the time... supplies and reimburse the Hazardous Substance Superfund for EPA's interest in the current fair market...

36 CFR 1250.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... requester seeking information for a use or purpose that furthers the commercial, trade, or profit interests... professional education, or an institution of vocational education, that operates a program of scholarly... information that is about current events or that would be of current interest to the public. Examples of news...

ISIS and META projects

NASA Technical Reports Server (NTRS)

Birman, Kenneth; Cooper, Robert; Marzullo, Keith

1990-01-01

The ISIS project has developed a new methodology, virtual synchony, for writing robust distributed software. High performance multicast, large scale applications, and wide area networks are the focus of interest. Several interesting applications that exploit the strengths of ISIS, including an NFS-compatible replicated file system, are being developed. The META project is distributed control in a soft real-time environment incorporating feedback. This domain encompasses examples as diverse as monitoring inventory and consumption on a factory floor, and performing load-balancing on a distributed computing system. One of the first uses of META is for distributed application management: the tasks of configuring a distributed program, dynamically adapting to failures, and monitoring its performance. Recent progress and current plans are reported.

A current affair: electrotherapy in wound healing

PubMed Central

Hunckler, Jerome; de Mel, Achala

2017-01-01

New developments in accelerating wound healing can have immense beneficial socioeconomic impact. The wound healing process is a highly orchestrated series of mechanisms where a multitude of cells and biological cascades are involved. The skin battery and current of injury mechanisms have become topics of interest for their influence in chronic wounds. Electrostimulation therapy of wounds has shown to be a promising treatment option with no-device-related adverse effects. This review presents an overview of the understanding and use of applied electrical current in various aspects of wound healing. Rapid clinical translation of the evolving understanding of biomolecular mechanisms underlying the effects of electrical simulation on wound healing would positively impact upon enhancing patient’s quality of life. PMID:28461755

NNEPEQ: Chemical equilibrium version of the Navy/NASA Engine Program

NASA Technical Reports Server (NTRS)

Fishbach, Laurence H.; Gordon, Sanford

1988-01-01

The Navy NASA Engine Program, NNEP, currently is in use at a large number of government agencies, commercial companies and universities. This computer code has bee used extensively to calculate the design and off-design (matched) performance of a broad range of turbine engines, ranging from subsonic turboprops to variable cycle engines for supersonic transports. Recently, there has been increased interest in applications for which NNEP was not capable of simulating, namely, high Mach applications, alternate fuels including cryogenics, and cycles such as the gas generator air-turbo-rocker (ATR). In addition, there is interest in cycles employing ejectors such as for military fighters. New engine component models had to be created for incorporation into NNEP, and it was found necessary to include chemical dissociation effects of high temperature gases. The incorporation of these extended capabilities into NNEP is discussed and some of the effects of these changes are illustrated.

Tacky COC: a solvent bonding technique for fabrication of microfluidic systems

NASA Astrophysics Data System (ADS)

Keller, Nico; Nargang, Tobias M.; Helmer, Dorothea; Rapp, Bastian E.

2016-03-01

The academic community knows cyclic olefin copolymer (COC) as a well suited material for microfluidic applications because COC has numerous interesting properties such as high transmittance, good chemical resistance and good biocompatibility. Here we present a fast and cost-effective method for bonding of two COC substrates: exposure to appropriate solvents gives a tacky COC surface which when brought in contact with untreated COC forms a strong and optical clear bond. The bonding process is carried out at room temperature and takes less than three minutes which makes it significantly faster than currently described methods: This method does not require special lab equipment such as hot plates or hydraulic presses. The mild conditions of the bond process also allow for such "tacky COC" lids to be used for sealing of microfluidic chips containing immobilized protein patterns which is of high interest for immunodiagnostic testing inside microfluidic chips.

NNEPEQ - Chemical equilibrium version of the Navy/NASA Engine Program

NASA Technical Reports Server (NTRS)

Fishbach, L. H.; Gordon, S.

1989-01-01

The Navy NASA Engine Program, NNEP, currently is in use at a large number of government agencies, commercial companies and universities. This computer code has been used extensively to calculate the design and off-design (matched) performance of a broad range of turbine engines, ranging from subsonic turboprops to variable cycle engines for supersonic transports. Recently, there has been increased interest in applications for which NNEP was not capable of simulating, namely, high Mach applications, alternate fuels including cryogenics, and cycles such as the gas generator air-turbo-rocker (ATR). In addition, there is interest in cycles employing ejectors such as for military fighters. New engine component models had to be created for incorporation into NNEP, and it was found necessary to include chemical dissociation effects of high temperature gases. The incorporation of these extended capabilities into NNEP is discussed and some of the effects of these changes are illustrated.

Consumer awareness and attitudes related to new potential reduced-exposure tobacco product brands.

PubMed

Parascandola, Mark; Augustson, Erik; O'Connell, Mary E; Marcus, Stephen

2009-07-01

In recent years, there has been a proliferation of potential reduced-exposure tobacco products (PREPs) marketed that claim to be less harmful or less addictive, compared with conventional cigarettes. Tobacco control scientists have raised concerns about the potential adverse impact of marketing of these products for smoking prevention and cessation efforts. Although these products have not been widely used among smokers, there are few data available on consumers' awareness and attitudes toward these products. Data were obtained from the 2003 and 2005 Health Information National Trends Survey, a nationally representative telephone survey of adults 18 years and older regarding health communication and associated beliefs and behaviors. Our study population consisted of 6,369 respondents in 2003 and 5,586 respondents in 2005, of whom 19% were current smokers and 28% were former smokers. In 2005, 45% of respondents had heard of at least one PREP product, while only 4.8% had actually tried one. Awareness and use were substantially higher among current smokers (55.6% and 12.7%). Awareness was highest for Marlboro Ultra Smooth (MUS) (30.2%), Eclipse (18.2%), Quest (7.8%), and Ariva (5.4%), while less than 2% for any other product. Of respondents who had tried a PREP, 50% cited harm reduction or assistance in quitting as a reason for trying the product and 30% believed that the product was less harmful than their usual brand. In the combined 2003 and 2005 dataset, 54.4% of current smokers stated that they would be "very" or "somewhat" interested in trying a cigarette advertised as less harmful, while only 3.2% of former smokers and 1.1% of never-smokers were interested. Among current smokers, interest was higher in females and non-Hispanic Whites, and among daily smokers, those who smoked 20 or more cigarettes per day and those who were not considering quitting. Smokers interested in PREPs were substantially more likely to rate their perceived lung cancer risk as high (40.3% vs. 8.3%) and to worry frequently about developing lung cancer (19.7% vs. 4%). These results suggest that there is a substantial level of interest among current smokers in cigarettes marketed with claims of reduced exposure or harm. Of particular concern is that "health conscious" smokers and heavy smokers not planning to quit may be especially vulnerable to PREP marketing messages and view such products as an alternative to smoking cessation.

Consumer awareness and attitudes related to new potential reduced-exposure tobacco product brands

PubMed Central

Augustson, Erik; O’Connell, Mary E.; Marcus, Stephen

2009-01-01

Introduction: In recent years, there has been a proliferation of potential reduced-exposure tobacco products (PREPs) marketed that claim to be less harmful or less addictive, compared with conventional cigarettes. Tobacco control scientists have raised concerns about the potential adverse impact of marketing of these products for smoking prevention and cessation efforts. Although these products have not been widely used among smokers, there are few data available on consumers’ awareness and attitudes toward these products. Methods: Data were obtained from the 2003 and 2005 Health Information National Trends Survey, a nationally representative telephone survey of adults 18 years and older regarding health communication and associated beliefs and behaviors. Our study population consisted of 6,369 respondents in 2003 and 5,586 respondents in 2005, of whom 19% were current smokers and 28% were former smokers. Results: In 2005, 45% of respondents had heard of at least one PREP product, while only 4.8% had actually tried one. Awareness and use were substantially higher among current smokers (55.6% and 12.7%). Awareness was highest for Marlboro Ultra Smooth (MUS) (30.2%), Eclipse (18.2%), Quest (7.8%), and Ariva (5.4%), while less than 2% for any other product. Of respondents who had tried a PREP, 50% cited harm reduction or assistance in quitting as a reason for trying the product and 30% believed that the product was less harmful than their usual brand. In the combined 2003 and 2005 dataset, 54.4% of current smokers stated that they would be “very” or “somewhat” interested in trying a cigarette advertised as less harmful, while only 3.2% of former smokers and 1.1% of never-smokers were interested. Among current smokers, interest was higher in females and non-Hispanic Whites, and among daily smokers, those who smoked 20 or more cigarettes per day and those who were not considering quitting. Smokers interested in PREPs were substantially more likely to rate their perceived lung cancer risk as high (40.3% vs. 8.3%) and to worry frequently about developing lung cancer (19.7% vs. 4%). Discussion: These results suggest that there is a substantial level of interest among current smokers in cigarettes marketed with claims of reduced exposure or harm. Of particular concern is that “health conscious” smokers and heavy smokers not planning to quit may be especially vulnerable to PREP marketing messages and view such products as an alternative to smoking cessation. PMID:19541949

Communities of Practice: Professional Development Through Fostering Connections

NASA Astrophysics Data System (ADS)

Ali, N. A.; Raftery, C.; Shackleford, R.; Nelson, A.; Turney, D.

2015-11-01

A community of practice is a group of people informally bound together by shared expertise and passion for a joint enterprise. Through facilitated discussion, we will share best practices and research about communities of practice, and explore how they evolve as they grow. The target audience for this Special Interest Group session is Education and Public Outreach professionals who are interested in using communities of practice as a way to support the professional development of their audiences. This session will be of interest to people who want to learn more about communities of practice as well as those who are currently coordinating similar efforts. Participants will have the opportunity to share their challenges and success, as well as gain new ideas for the planning, implementation, and expansion of efforts. This session will be facilitated by the coordinators of NASA's SMD Heliophysics EPO Forum online community of practice for middle and high school science teachers.

Computational design of auxotrophy-dependent microbial biosensors for combinatorial metabolic engineering experiments.

PubMed

Tepper, Naama; Shlomi, Tomer

2011-01-21

Combinatorial approaches in metabolic engineering work by generating genetic diversity in a microbial population followed by screening for strains with improved phenotypes. One of the most common goals in this field is the generation of a high rate chemical producing strain. A major hurdle with this approach is that many chemicals do not have easy to recognize attributes, making their screening expensive and time consuming. To address this problem, it was previously suggested to use microbial biosensors to facilitate the detection and quantification of chemicals of interest. Here, we present novel computational methods to: (i) rationally design microbial biosensors for chemicals of interest based on substrate auxotrophy that would enable their high-throughput screening; (ii) predict engineering strategies for coupling the synthesis of a chemical of interest with the production of a proxy metabolite for which high-throughput screening is possible via a designed bio-sensor. The biosensor design method is validated based on known genetic modifications in an array of E. coli strains auxotrophic to various amino-acids. Predicted chemical production rates achievable via the biosensor-based approach are shown to potentially improve upon those predicted by current rational strain design approaches. (A Matlab implementation of the biosensor design method is available via http://www.cs.technion.ac.il/~tomersh/tools).

How do self-interest and other-need interact in the brain to determine altruistic behavior?

PubMed

Hu, Jie; Li, Yue; Yin, Yunlu; Blue, Philip R; Yu, Hongbo; Zhou, Xiaolin

2017-08-15

Altruistic behavior, i.e., promoting the welfare of others at a cost to oneself, is subserved by the integration of various social, affective, and economic factors represented in extensive brain regions. However, it is unclear how different regions interact to process/integrate information regarding the helper's interest and recipient's need when deciding whether to behave altruistically. Here we combined an interactive game with functional Magnetic Resonance Imaging (fMRI) and transcranial direct current stimulation (tDCS) to characterize the neural network underlying the processing/integration of self-interest and other-need. At the behavioral level, high self-risk decreased helping behavior and high other-need increased helping behavior. At the neural level, activity in medial prefrontal cortex (MPFC) and right dorsolateral prefrontal cortex (rDLPFC) were positively associated with self-risk levels, and activity in right inferior parietal lobe (rIPL) and rDLPFC were negatively associated with other-need levels. Dynamic causal modeling further suggested that both MPFC and rIPL were extrinsically connected to rDLPFC; high self-risk enhanced the effective connectivity from MPFC to rDLPFC, and the modulatory effect of other-need on the connectivity from rIPL to rDLPFC positively correlated with the modulatory effect of other-need on individuals' helping rate. Two tDCS experiments provided causal evidence that rDLPFC affects both self-interest and other-need concerns, and rIPL selectively affects the other-need concerns. These findings suggest a crucial role of the MPFC-IPL-DLPFC network during altruistic decision-making, with rDLPFC as a central node for integrating and modulating motives regarding self-interest and other-need. Copyright © 2017. Published by Elsevier Inc.

Leakage current and charging/discharging processes in barrier-type anodic alumina thin films for use in metal-insulator-metal capacitors

NASA Astrophysics Data System (ADS)

Hourdakis, E.; Koutsoureli, M.; Papaioannou, G.; Nassiopoulou, A. G.

2018-06-01

Barrier-type anodic alumina thin films are interesting for use in high capacitance density metal-insulator-metal capacitors due to their excellent dielectric properties at small thickness. This thickness is easily controlled by the anodization voltage. In previous papers we studied the main parameters of interest of the Al/barrier-type anodic alumina/Al structure for use in RF applications and showed the great potential of barrier-type anodic alumina in this respect. In this paper, we investigated in detail charging/discharging processes and leakage current of the above dielectric material. Two different sets of metal-insulator-metal capacitors were studied, namely, with the top Al electrode being either e-gun deposited or sputtered. The dielectric constant of the barrier-type anodic alumina was found at 9.3. Low leakage current was observed in all samples studied. Furthermore, depending on the film thickness, field emission following the Fowler-Nordheim mechanism was observed above an applied electric field. Charging of the anodic dielectric was observed, occurring in the bulk of the anodic layer. The stored charge was of the order of few μC/cm2 and the calculated trap density ˜2 × 1018 states/cm3, the most probable origin of charge traps being, in our opinion, positive electrolyte ions trapped in the dielectric during anodization. We do not think that oxygen vacancies play an important role, since their existence would have a more important impact on the leakage current characteristics, such as resistive memory effects or significant changes during annealing, which were not observed. Finally, discharging characteristic times as high as 5 × 109 s were measured.

Complement evasion by Bordetella pertussis: implications for improving current vaccines.

PubMed

Jongerius, Ilse; Schuijt, Tim J; Mooi, Frits R; Pinelli, Elena

2015-04-01

Bordetella pertussis causes whooping cough or pertussis, a highly contagious disease of the respiratory tract. Despite high vaccination coverage, reported cases of pertussis are rising worldwide and it has become clear that the current vaccines must be improved. In addition to the well-known protective role of antibodies and T cells during B. pertussis infection, innate immune responses such as the complement system play an essential role in B. pertussis killing. In order to evade this complement activation and colonize the human host, B. pertussis expresses several molecules that inhibit complement activation. Interestingly, one of the known complement evasion proteins, autotransporter Vag8, is highly expressed in the recently emerged B. pertussis isolates. Here, we describe the current knowledge on how B. pertussis evades complement-mediated killing. In addition, we compare this to complement evasion strategies used by other bacterial species. Finally, we discuss the consequences of complement evasion by B. pertussis on adaptive immunity and how identification of the bacterial molecules and the mechanisms involved in complement evasion might help improve pertussis vaccines.

High resolution multibeam and hydrodynamic datasets of tidal channels and inlets of the Venice Lagoon

NASA Astrophysics Data System (ADS)

Madricardo, Fantina; Foglini, Federica; Kruss, Aleksandra; Ferrarin, Christian; Pizzeghello, Nicola Marco; Murri, Chiara; Rossi, Monica; Bajo, Marco; Bellafiore, Debora; Campiani, Elisabetta; Fogarin, Stefano; Grande, Valentina; Janowski, Lukasz; Keppel, Erica; Leidi, Elisa; Lorenzetti, Giuliano; Maicu, Francesco; Maselli, Vittorio; Mercorella, Alessandra; Montereale Gavazzi, Giacomo; Minuzzo, Tiziano; Pellegrini, Claudio; Petrizzo, Antonio; Prampolini, Mariacristina; Remia, Alessandro; Rizzetto, Federica; Rovere, Marzia; Sarretta, Alessandro; Sigovini, Marco; Sinapi, Luigi; Umgiesser, Georg; Trincardi, Fabio

2017-09-01

Tidal channels are crucial for the functioning of wetlands, though their morphological properties, which are relevant for seafloor habitats and flow, have been understudied so far. Here, we release a dataset composed of Digital Terrain Models (DTMs) extracted from a total of 2,500 linear kilometres of high-resolution multibeam echosounder (MBES) data collected in 2013 covering the entire network of tidal channels and inlets of the Venice Lagoon, Italy. The dataset comprises also the backscatter (BS) data, which reflect the acoustic properties of the seafloor, and the tidal current fields simulated by means of a high-resolution three-dimensional unstructured hydrodynamic model. The DTMs and the current fields help define how morphological and benthic properties of tidal channels are affected by the action of currents. These data are of potential broad interest not only to geomorphologists, oceanographers and ecologists studying the morphology, hydrodynamics, sediment transport and benthic habitats of tidal environments, but also to coastal engineers and stakeholders for cost-effective monitoring and sustainable management of this peculiar shallow coastal system.

High resolution multibeam and hydrodynamic datasets of tidal channels and inlets of the Venice Lagoon

PubMed Central

Madricardo, Fantina; Foglini, Federica; Kruss, Aleksandra; Ferrarin, Christian; Pizzeghello, Nicola Marco; Murri, Chiara; Rossi, Monica; Bajo, Marco; Bellafiore, Debora; Campiani, Elisabetta; Fogarin, Stefano; Grande, Valentina; Janowski, Lukasz; Keppel, Erica; Leidi, Elisa; Lorenzetti, Giuliano; Maicu, Francesco; Maselli, Vittorio; Mercorella, Alessandra; Montereale Gavazzi, Giacomo; Minuzzo, Tiziano; Pellegrini, Claudio; Petrizzo, Antonio; Prampolini, Mariacristina; Remia, Alessandro; Rizzetto, Federica; Rovere, Marzia; Sarretta, Alessandro; Sigovini, Marco; Sinapi, Luigi; Umgiesser, Georg; Trincardi, Fabio

2017-01-01

Tidal channels are crucial for the functioning of wetlands, though their morphological properties, which are relevant for seafloor habitats and flow, have been understudied so far. Here, we release a dataset composed of Digital Terrain Models (DTMs) extracted from a total of 2,500 linear kilometres of high-resolution multibeam echosounder (MBES) data collected in 2013 covering the entire network of tidal channels and inlets of the Venice Lagoon, Italy. The dataset comprises also the backscatter (BS) data, which reflect the acoustic properties of the seafloor, and the tidal current fields simulated by means of a high-resolution three-dimensional unstructured hydrodynamic model. The DTMs and the current fields help define how morphological and benthic properties of tidal channels are affected by the action of currents. These data are of potential broad interest not only to geomorphologists, oceanographers and ecologists studying the morphology, hydrodynamics, sediment transport and benthic habitats of tidal environments, but also to coastal engineers and stakeholders for cost-effective monitoring and sustainable management of this peculiar shallow coastal system. PMID:28872636

High resolution multibeam and hydrodynamic datasets of tidal channels and inlets of the Venice Lagoon.

PubMed

Madricardo, Fantina; Foglini, Federica; Kruss, Aleksandra; Ferrarin, Christian; Pizzeghello, Nicola Marco; Murri, Chiara; Rossi, Monica; Bajo, Marco; Bellafiore, Debora; Campiani, Elisabetta; Fogarin, Stefano; Grande, Valentina; Janowski, Lukasz; Keppel, Erica; Leidi, Elisa; Lorenzetti, Giuliano; Maicu, Francesco; Maselli, Vittorio; Mercorella, Alessandra; Montereale Gavazzi, Giacomo; Minuzzo, Tiziano; Pellegrini, Claudio; Petrizzo, Antonio; Prampolini, Mariacristina; Remia, Alessandro; Rizzetto, Federica; Rovere, Marzia; Sarretta, Alessandro; Sigovini, Marco; Sinapi, Luigi; Umgiesser, Georg; Trincardi, Fabio

2017-09-05

Tidal channels are crucial for the functioning of wetlands, though their morphological properties, which are relevant for seafloor habitats and flow, have been understudied so far. Here, we release a dataset composed of Digital Terrain Models (DTMs) extracted from a total of 2,500 linear kilometres of high-resolution multibeam echosounder (MBES) data collected in 2013 covering the entire network of tidal channels and inlets of the Venice Lagoon, Italy. The dataset comprises also the backscatter (BS) data, which reflect the acoustic properties of the seafloor, and the tidal current fields simulated by means of a high-resolution three-dimensional unstructured hydrodynamic model. The DTMs and the current fields help define how morphological and benthic properties of tidal channels are affected by the action of currents. These data are of potential broad interest not only to geomorphologists, oceanographers and ecologists studying the morphology, hydrodynamics, sediment transport and benthic habitats of tidal environments, but also to coastal engineers and stakeholders for cost-effective monitoring and sustainable management of this peculiar shallow coastal system.

Study of reflection gratings recorded in polyvinyl alcohol/acrylamide-based photopolymer.

PubMed

Fuentes, Rosa; Fernández, Elena; García, Celia; Beléndez, Augusto; Pascual, Inmaculada

2009-12-01

High-spatial-frequency fringes associated with reflection holographic optical elements are difficult to obtain with currently available recording materials. In this work, holographic reflection gratings were stored in a polyvinyl alcohol/acrylamide photopolymer. This material is formed of acrylamide photopolymer, which is considered interesting material for optical storage applications such as holographic memories. The experimental procedure for examining the high-spatial-frequency response of this material is explained, and the experimental results obtained are presented. With the aim of obtaining the best results, the performance of different material compositions is compared.

Imaging of current density distributions with a Nb weak-link scanning nano-SQUID microscope

PubMed Central

Shibata, Yusuke; Nomura, Shintaro; Kashiwaya, Hiromi; Kashiwaya, Satoshi; Ishiguro, Ryosuke; Takayanagi, Hideaki

2015-01-01

Superconducting quantum interference devices (SQUIDs) are accepted as one of the highest magnetic field sensitive probes. There are increasing demands to image local magnetic fields to explore spin properties and current density distributions in a two-dimensional layer of semiconductors or superconductors. Nano-SQUIDs have recently attracting much interest for high spatial resolution measurements in nanometer-scale samples. Whereas weak-link Dayem Josephson junction nano-SQUIDs are suitable to miniaturization, hysteresis in current-voltage (I-V) characteristics that is often observed in Dayem Josephson junction is not desirable for a scanning microscope. Here we report on our development of a weak-link nano-SQUIDs scanning microscope with small hysteresis in I-V curve and on reconstructions of two-dimensional current density vector in two-dimensional electron gas from measured magnetic field. PMID:26459874

Imaging of current density distributions with a Nb weak-link scanning nano-SQUID microscope

NASA Astrophysics Data System (ADS)

Shibata, Yusuke; Nomura, Shintaro; Kashiwaya, Hiromi; Kashiwaya, Satoshi; Ishiguro, Ryosuke; Takayanagi, Hideaki

2015-10-01

Superconducting quantum interference devices (SQUIDs) are accepted as one of the highest magnetic field sensitive probes. There are increasing demands to image local magnetic fields to explore spin properties and current density distributions in a two-dimensional layer of semiconductors or superconductors. Nano-SQUIDs have recently attracting much interest for high spatial resolution measurements in nanometer-scale samples. Whereas weak-link Dayem Josephson junction nano-SQUIDs are suitable to miniaturization, hysteresis in current-voltage (I-V) characteristics that is often observed in Dayem Josephson junction is not desirable for a scanning microscope. Here we report on our development of a weak-link nano-SQUIDs scanning microscope with small hysteresis in I-V curve and on reconstructions of two-dimensional current density vector in two-dimensional electron gas from measured magnetic field.

Flexible, Low-Power Thin-Film Transistors Made of Vapor-Phase Synthesized High-k, Ultrathin Polymer Gate Dielectrics.

PubMed

Choi, Junhwan; Joo, Munkyu; Seong, Hyejeong; Pak, Kwanyong; Park, Hongkeun; Park, Chan Woo; Im, Sung Gap

2017-06-21

A series of high-k, ultrathin copolymer gate dielectrics were synthesized from 2-cyanoethyl acrylate (CEA) and di(ethylene glycol) divinyl ether (DEGDVE) monomers by a free radical polymerization via a one-step, vapor-phase, initiated chemical vapor deposition (iCVD) method. The chemical composition of the copolymers was systematically optimized by tuning the input ratio of the vaporized CEA and DEGDVE monomers to achieve a high dielectric constant (k) as well as excellent dielectric strength. Interestingly, DEGDVE was nonhomopolymerizable but it was able to form a copolymer with other kinds of monomers. Utilizing this interesting property of the DEGDVE cross-linker, the dielectric constant of the copolymer film could be maximized with minimum incorporation of the cross-linker moiety. To our knowledge, this is the first report on the synthesis of a cyanide-containing polymer in the vapor phase, where a high-purity polymer film with a maximized dielectric constant was achieved. The dielectric film with the optimized composition showed a dielectric constant greater than 6 and extremely low leakage current densities (<3 × 10 -8 A/cm 2 in the range of ±2 MV/cm), with a thickness of only 20 nm, which is an outstanding thickness for down-scalable cyanide polymer dielectrics. With this high-k dielectric layer, organic thin-film transistors (OTFTs) and oxide TFTs were fabricated, which showed hysteresis-free transfer characteristics with an operating voltage of less than 3 V. Furthermore, the flexible OTFTs retained their low gate leakage current and ideal TFT characteristics even under 2% applied tensile strain, which makes them some of the most flexible OTFTs reported to date. We believe that these ultrathin, high-k organic dielectric films with excellent mechanical flexibility will play a crucial role in future soft electronics.

Emotion-Related Regulation: An Emerging Construct

ERIC Educational Resources Information Center

Eisenberg, Nancy; Champion, Claire; Ma, Yue

2004-01-01

Emotion-related regulation is a topic of considerable current interest; however, this was not always true. We briefly discuss the history of interest in the topic and then the current state of the field, including definitions of the construct. In addition, we summarize some of the important issues for future attention, including definitional…

Availability and performance of image/video-based vital signs monitoring methods: a systematic review protocol.

PubMed

Harford, Mirae; Catherall, Jacqueline; Gerry, Stephen; Young, Duncan; Watkinson, Peter

2017-10-25

For many vital signs, monitoring methods require contact with the patient and/or are invasive in nature. There is increasing interest in developing still and video image-guided monitoring methods that are non-contact and non-invasive. We will undertake a systematic review of still and video image-based monitoring methods. We will perform searches in multiple databases which include MEDLINE, Embase, CINAHL, Cochrane library, IEEE Xplore and ACM Digital Library. We will use OpenGrey and Google searches to access unpublished or commercial data. We will not use language or publication date restrictions. The primary goal is to summarise current image-based vital signs monitoring methods, limited to heart rate, respiratory rate, oxygen saturations and blood pressure. Of particular interest will be the effectiveness of image-based methods compared to reference devices. Other outcomes of interest include the quality of the method comparison studies with respect to published reporting guidelines, any limitations of non-contact non-invasive technology and application in different populations. To the best of our knowledge, this is the first systematic review of image-based non-contact methods of vital signs monitoring. Synthesis of currently available technology will facilitate future research in this highly topical area. PROSPERO CRD42016029167.

High current density 2D/3D MoS2/GaN Esaki tunnel diodes

NASA Astrophysics Data System (ADS)

Krishnamoorthy, Sriram; Lee, Edwin W.; Lee, Choong Hee; Zhang, Yuewei; McCulloch, William D.; Johnson, Jared M.; Hwang, Jinwoo; Wu, Yiying; Rajan, Siddharth

2016-10-01

The integration of two-dimensional materials such as transition metal dichalcogenides with bulk semiconductors offer interesting opportunities for 2D/3D heterojunction-based device structures without any constraints of lattice matching. By exploiting the favorable band alignment at the GaN/MoS2 heterojunction, an Esaki interband tunnel diode is demonstrated by transferring large area Nb-doped, p-type MoS2 onto heavily n-doped GaN. A peak current density of 446 A/cm2 with repeatable room temperature negative differential resistance, peak to valley current ratio of 1.2, and minimal hysteresis was measured in the MoS2/GaN non-epitaxial tunnel diode. A high current density of 1 kA/cm2 was measured in the Zener mode (reverse bias) at -1 V bias. The GaN/MoS2 tunnel junction was also modeled by treating MoS2 as a bulk semiconductor, and the electrostatics at the 2D/3D interface was found to be crucial in explaining the experimentally observed device characteristics.

A Chemogenetic Receptor That Enhances the Magnitude and Frequency of Glycinergic Inhibitory Postsynaptic Currents without Inducing a Tonic Chloride Flux.

PubMed

Islam, Robiul; Zhang, Yan; Xu, Li; Sah, Pankaj; Lynch, Joseph W

2017-03-15

The gene transfer-mediated expression of inhibitory ion channels in nociceptive neurons holds promise for treating intractable pain. Chemogenetics, which involves expressing constructs activated by biologically inert molecules, is of particular interest as it permits tunable neuromodulation. However, current chloride-permeable chemogenetic constructs are problematic as they mediate a tonic chloride influx which over time would deplete the chloride electrochemical gradient and reduce inhibitory efficacy. Inflammatory pain sensitization can be caused by prostaglandin E2-mediated inhibition of glycinergic inhibitory postsynaptic currents in spinal nociceptive neurons. We developed a highly conducting (100 pS) inhibitory chemogenetic construct based on a human glycine receptor (α1 Y279F,A288G ) with high ivermectin sensitivity. When virally infected into spinal neurons, 10 nM ivermectin increased the magnitude and frequency of glycinergic postsynaptic currents without activating a tonic chloride flux. The construct should thus produce analgesia. Its human origin and the well-established biocompatibility of its ligand suggest it may be suited to human use.

High Temperature Polymers for use in Fuel Cells

NASA Technical Reports Server (NTRS)

Peplowski, Katherine M.

2004-01-01

NASA Glenn Research Center (GRC) is currently working on polymers for fuel cell and lithium battery applications. The desire for more efficient, higher power density, and a lower environmental impact power sources has led to interest in proton exchanges membrane fuels cells (PEMFC) and lithium batteries. A PEMFC has many advantages as a power source. The fuel cell uses oxygen and hydrogen as reactants. The resulting products are electricity, heat, and water. The PEMFC consists of electrodes with a catalyst, and an electrolyte. The electrolyte is an ion-conducting polymer that transports protons from the anode to the cathode. Typically, a PEMFC is operated at a temperature of about 80 C. There is intense interest in developing a fuel cell membrane that can operate at higher temperatures in the range of 80 C- 120 C. Operating the he1 cell at higher temperatures increases the kinetics of the fuel cell reaction as well as decreasing the susceptibility of the catalyst to be poisoned by impurities. Currently, Nafion made by Dupont is the most widely used polymer membrane in PEMFC. Nafion does not function well above 80 C due to a significant decrease in the conductivity of the membrane from a loss of hydration. In addition to the loss of conductivity at high temperatures, the long term stability and relatively high cost of Nafion have stimulated many researches to find a substitute for Nafion. Lithium ion batteries are popular for use in portable electronic devices, such as laptop computers and mobile phones. The high power density of lithium batteries makes them ideal for the high power demand of today s advanced electronics. NASA is developing a solid polymer electrolyte that can be used for lithium batteries. Solid polymer electrolytes have many advantages over the current gel or liquid based systems that are used currently. Among these advantages are the potential for increased power density and design flexibility. Automobiles, computers, and cell phones require highly efficient power density for lowering emissions and meeting increasing consumer demands. Many of the solutions can be provided by proton exchange membrane fuel cells and lithium batteries. NASA Glenn Research Center has recognized this need, and is presently engaged in a solution. The goals for the summer include mastering synthesis techniques, understanding the reactions occurring during the synthesis, and characterizing the resulting polymer membranes using NMR, DSC, and TGA for the PEMFC and lithium batteries.

An internet survey of the characteristics and physical activity of community-dwelling Australian adults with acquired brain injury: Exploring interest in an internet-delivered self-management program focused on physical activity.

PubMed

Jones, Taryn M; Dean, Catherine M; Dear, Blake F; Hush, Julia M; Titov, Nickolai

2016-01-01

Individuals with acquired brain injury (ABI) are more likely to be physically inactive and experience barriers to accessing services to address inactivity. This study was designed to guide the development of an internet-delivered self-management program to increase physical activity after ABI. The aims of this study were to examine the current physical activity status of community-dwelling Australian adults with ABI, the barriers to physical activity they experience and to explore interest an internet-delivered self-management program aimed at increasing physical activity. An online survey of Australian adults with ABI was used to collect information about demographic characteristics; general health; emotional well-being; mobility and physical activity status, and satisfaction; barriers to physical activity; confidence in overcoming barriers, and; interest in an internet self-management program. Data were analyzed descriptively and correlational analyses examined relationships between variables. Data were analyzed from 59 respondents. Over half were not satisfied with their current physical activity status. The most frequently reported barriers were pain/discomfort, fatigue and fear, and confidence to overcome these barriers was very low. Interest in an internet-delivered self-management program was high (74%) and not related to the amount of physical activity, satisfaction with physical activity and mobility status or total number of barriers. Australian adults with ABI are not satisfied with their activity levels and experience barriers in maintaining their physical activity levels. Participants were interested in accessing an internet-delivered self-management program aimed at improving physical activity levels. Therefore such a program warrants development and evaluation. Copyright © 2016 Elsevier Inc. All rights reserved.

Predicting Medical Students’ Current Attitudes Toward Psychiatry, Interest in Psychiatry, and Estimated Likelihood of Working in Psychiatry: A Cross-Sectional Study in Four European Countries

PubMed Central

Warnke, Ingeborg; Gamma, Alex; Buadze, Maria; Schleifer, Roman; Canela, Carlos; Strebel, Bernd; Tényi, Tamás; Rössler, Wulf; Rüsch, Nicolas; Liebrenz, Michael

2018-01-01

Psychiatry as a medical discipline is becoming increasingly important due to the high and increasing worldwide burden associated with mental disorders. Surprisingly, however, there is a lack of young academics choosing psychiatry as a career. Previous evidence on medical students’ perspectives is abundant but has methodological shortcomings. Therefore, by attempting to avoid previous shortcomings, we aimed to contribute to a better understanding of the predictors of the following three outcome variables: current medical students’ attitudes toward psychiatry, interest in psychiatry, and estimated likelihood of working in psychiatry. The sample consisted of N = 1,356 medical students at 45 medical schools in Germany and Austria as well as regions of Switzerland and Hungary with a German language curriculum. We used snowball sampling via Facebook with a link to an online questionnaire as recruitment procedure. Snowball sampling is based on referrals made among people. This questionnaire included a German version of the Attitudes Toward Psychiatry Scale (ATP-30-G) and further variables related to outcomes and potential predictors in terms of sociodemography (e.g., gender) or medical training (e.g., curriculum-related experience with psychiatry). Data were analyzed by linear mixed models and further regression models. On average, students had a positive attitude to and high general interest in, but low professional preference for, psychiatry. A neutral attitude to psychiatry was partly related to the discipline itself, psychiatrists, or psychiatric patients. Female gender and previous experience with psychiatry, particularly curriculum-related and personal experience, were important predictors of all outcomes. Students in the first years of medical training were more interested in pursuing psychiatry as a career. Furthermore, the country of the medical school was related to the outcomes. However, statistical models explained only a small proportion of variance. The findings indicate that particularly curriculum-related experience is important for determining attitudes toward psychiatry, interest in the subject and self-predicted professional career choice. We therefore encourage the provision of opportunities for clinical experience by psychiatrists. However, further predictor variables need to be considered in future studies. PMID:29593577

Predicting Medical Students' Current Attitudes Toward Psychiatry, Interest in Psychiatry, and Estimated Likelihood of Working in Psychiatry: A Cross-Sectional Study in Four European Countries.

PubMed

Warnke, Ingeborg; Gamma, Alex; Buadze, Maria; Schleifer, Roman; Canela, Carlos; Strebel, Bernd; Tényi, Tamás; Rössler, Wulf; Rüsch, Nicolas; Liebrenz, Michael

2018-01-01

Psychiatry as a medical discipline is becoming increasingly important due to the high and increasing worldwide burden associated with mental disorders. Surprisingly, however, there is a lack of young academics choosing psychiatry as a career. Previous evidence on medical students' perspectives is abundant but has methodological shortcomings. Therefore, by attempting to avoid previous shortcomings, we aimed to contribute to a better understanding of the predictors of the following three outcome variables: current medical students' attitudes toward psychiatry, interest in psychiatry, and estimated likelihood of working in psychiatry. The sample consisted of N  = 1,356 medical students at 45 medical schools in Germany and Austria as well as regions of Switzerland and Hungary with a German language curriculum. We used snowball sampling via Facebook with a link to an online questionnaire as recruitment procedure. Snowball sampling is based on referrals made among people. This questionnaire included a German version of the Attitudes Toward Psychiatry Scale (ATP-30-G) and further variables related to outcomes and potential predictors in terms of sociodemography (e.g., gender) or medical training (e.g., curriculum-related experience with psychiatry). Data were analyzed by linear mixed models and further regression models. On average, students had a positive attitude to and high general interest in, but low professional preference for, psychiatry. A neutral attitude to psychiatry was partly related to the discipline itself, psychiatrists, or psychiatric patients. Female gender and previous experience with psychiatry, particularly curriculum-related and personal experience, were important predictors of all outcomes. Students in the first years of medical training were more interested in pursuing psychiatry as a career. Furthermore, the country of the medical school was related to the outcomes. However, statistical models explained only a small proportion of variance. The findings indicate that particularly curriculum-related experience is important for determining attitudes toward psychiatry, interest in the subject and self-predicted professional career choice. We therefore encourage the provision of opportunities for clinical experience by psychiatrists. However, further predictor variables need to be considered in future studies.

Top-gated chemical vapor deposition grown graphene transistors with current saturation.

PubMed

Bai, Jingwei; Liao, Lei; Zhou, Hailong; Cheng, Rui; Liu, Lixin; Huang, Yu; Duan, Xiangfeng

2011-06-08

Graphene transistors are of considerable interest for radio frequency (rf) applications. In general, transistors with large transconductance and drain current saturation are desirable for rf performance, which is however nontrivial to achieve in graphene transistors. Here we report high-performance top-gated graphene transistors based on chemical vapor deposition (CVD) grown graphene with large transconductance and drain current saturation. The graphene transistors were fabricated with evaporated high dielectric constant material (HfO(2)) as the top-gate dielectrics. Length scaling studies of the transistors with channel length from 5.6 μm to 100 nm show that complete current saturation can be achieved in 5.6 μm devices and the saturation characteristics degrade as the channel length shrinks down to the 100-300 nm regime. The drain current saturation was primarily attributed to drain bias induced shift of the Dirac points. With the selective deposition of HfO(2) gate dielectrics, we have further demonstrated a simple scheme to realize a 300 nm channel length graphene transistors with self-aligned source-drain electrodes to achieve the highest transconductance of 250 μS/μm reported in CVD graphene to date.

Social Support and Performance in Complex Organizations.

DTIC Science & Technology

1984-01-30

which subjects’ perceptions of their parents ’ interest in and overprotection of them were related to current social support levels. The findings...support levels are related to subjects’ perceptions of experiences earlier in life. Using the Parental Bonding Instrument, studies were carried out in...indicated clearly that, while parental over-protection is unrelated to scores on the Social Sarason 7 Support Questionnaire there is a highly significant

Wind tunnel magnetic Suspension Systems at the University of Southampton, England

NASA Technical Reports Server (NTRS)

Goodyer, Michael J.

1992-01-01

The magnetic suspension system at Southampton University was used in two roles: as a device for producing useful aerodynamic data, and as a vehicle to develop and demonstrate new technology for application to a projected larger facility. Examples of both follow, beginning with an outline of the quest to develop methods for reaching high angles of attack because of current interest in researching the associated aerodynamics.

The evolving Alaska mapping program.

USGS Publications Warehouse

Brooks, P.D.; O'Brien, T. J.

1986-01-01

This paper describes the development of mapping in Alaska, the current status of the National Mapping Program, and future plans for expanding and improving the mapping coverage. Research projects with Landsat Multispectral Scanner and Return Vidicon imagery and real- and synthetic-aperture radar; image mapping programs; digital mapping; remote sensing projects; the Alaska National Interest Lands Conservation Act; and the Alaska High-Altitude Aerial Photography Program are also discussed.-from Authors

Superconducting Magnet Technology for Future High Energy Proton Colliders

NASA Astrophysics Data System (ADS)

Gourlay, Stephen

2017-01-01

Interest in high field dipoles has been given a boost by new proposals to build a high-energy proton-proton collider to follow the LHC and programs around the world are taking on the task to answer the need. Studies aiming toward future high-energy proton-proton colliders at the 100 TeV scale are now being organized. The LHC and current cost models are based on technology close to four decades old and point to a broad optimum of operation using dipoles with fields between 5 and 12T when site constraints, either geographical or political, are not a factor. Site geography constraints that limit the ring circumference can drive the required dipole field up to 20T, which is more than a factor of two beyond state-of-the-art. After a brief review of current progress, the talk will describe the challenges facing future development and present a roadmap for moving high field accelerator magnet technology forward. This work was supported by the Director, Office of Science, High Energy Physics, US Department of Energy, under contract No. DE-AC02-05CH11231.

High-frequency effects in antiferromagnetic Sr3Ir2O7

NASA Astrophysics Data System (ADS)

Williamson, Morgan; Seinige, Heidi; Shen, Shida; Wang, Cheng; Cao, Gang; Zhou, Jianshi; Goodenough, John; Tsoi, Maxim

Antiferromagnetic (AFM) spintronics is one of many promising routes for `beyond the CMOS' technologies where unique properties of AFM materials are exploited to achieve new and improved functionalities. AFMs are especially interesting for high-speed memory applications thanks to their high natural frequencies. Here we report the effects of high-frequency (microwave) currents on transport properties of antiferromagnetic Mott insulator Sr3Ir2O7. The microwaves at 3-7 GHz were found to affect the material's current-voltage characteristic and produce resonance-like features that we tentatively associate with the dissipationless magnonics recently predicted to occur in antiferromagnetic insulators subject to ac electric fields. Our observations support the potential of antiferromagnetic materials for high-speed/high-frequency spintronic applications. This work was supported in part by C-SPIN, one of six centers of STARnet, a Semiconductor Research Corporation program, sponsored by MARCO and DARPA, by NSF Grants DMR-1207577, DMR-1265162, DMR-1600057, and DMR-1122603, and by the King Abdullah University of Science and Technology (KAUST) Office of Sponsored Research (OSR) under Award No. OSR-2015-CRG4-2626.

29 CFR 20.58 - Rate of interest.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 1 2010-07-01 2010-07-01 true Rate of interest. 20.58 Section 20.58 Labor Office of the Secretary of Labor FEDERAL CLAIMS COLLECTION Interest, Penalties and Administrative Costs § 20.58 Rate of interest. (a) The rate of interest assessed shall be the rate of the current value of funds to the United...

Social Orienting and Attention Is Influenced by the Presence of Competing Nonsocial Information in Adolescents with Autism

PubMed Central

Unruh, Kathryn E.; Sasson, Noah J.; Shafer, Robin L.; Whitten, Allison; Miller, Stephanie J.; Turner-Brown, Lauren; Bodfish, James W.

2016-01-01

Background: Our experiences with the world play a critical role in neural and behavioral development. Children with autism spectrum disorder (ASD) spend a disproportionate amount of time seeking out, attending to, and engaging with aspects of their environment that are largely nonsocial in nature. In this study we adapted an established method for eliciting and quantifying aspects of visual choice behavior related to preference to test the hypothesis that preference for nonsocial sources of stimulation diminishes orientation and attention to social sources of stimulation in children with ASD. Method: Preferential viewing tasks can serve as objective measures of preference, with a greater proportion of viewing time to one item indicative of increased preference. The current task used gaze-tracking technology to examine patterns of visual orientation and attention to stimulus pairs that varied in social (faces) and nonsocial content (high autism interest or low autism interest). Participants included both adolescents diagnosed with ASD and typically developing; groups were matched on IQ and gender. Results: Repeated measures ANOVA revealed that individuals with ASD had a significantly greater latency to first fixate on social images when this image was paired with a high autism interest image, compared to a low autism interest image pairing. Participants with ASD showed greater total look time to objects, while typically developing participants preferred to look at faces. Groups also differed in number and average duration of fixations to social and object images. In the ASD group only, a measure of nonsocial interest was associated with reduced preference for social images when paired with high autism interest images. Conclusions: In ASD, the presence of nonsocial sources of stimulation can significantly increase the latency of look time to social sources of information. These results suggest that atypicalities in social motivation in ASD may be context-dependent, with a greater degree of plasticity than is assumed by existing social motivation accounts of ASD. PMID:28066169

Induction of auroral zone electric currents within the Alaska pipeline

USGS Publications Warehouse

Campbell, W.H.

1978-01-01

The Alaskar pipeline is a highly conducting anomaly extending 800 miles (1300 km) from about 62?? to 69?? geomagnetic latitude beneath the most active regions of the ionospheric electrojet current. The spectral behavior of the magnetic field from this current was analyzed using data from standard geomagnetic observatories to establish the predictable patterns of temporal and spatial changes for field pulsation periods between 5 min and 4 hr. Such behavior is presented in a series of tables, graphs and formulae. Using 2- and 3-layer models of the conducting earth, the induced electric fields associated with the geomagnetic changes were established. From the direct relationship of the current to the geomagnetic field variation patterns one can infer counterpart temporal and spatial characteristics of the pipeline current. The relationship of the field amplitudes to geomagnetic activity indices, Ap, and the established occurrence of various levels of Ap over several solar cycles were employed to show that about half of the time the induced currents in the pipe would be under 1 A for the maximum response oscillatory periods near 1 hr. Such currents should be of minimal consequence in corrosion effects for even a section of the pipeline unprotected by sacrificial electrodes. Of greater interest was the result that the extreme surges of current should reach over one-hundred amperes in the pipeline during high activity. ?? 1978 Birkha??user Verlag.

Surface Currents and Winds at the Delaware Bay Mouth

DOE Office of Scientific and Technical Information (OSTI.GOV)

Muscarella, P A; Barton, N P; Lipphardt, B L

2011-04-06

Knowledge of the circulation of estuaries and adjacent shelf waters has relied on hydrographic measurements, moorings, and local wind observations usually removed from the region of interest. Although these observations are certainly sufficient to identify major characteristics, they lack both spatial resolution and temporal coverage. High resolution synoptic observations are required to identify important coastal processes at smaller scales. Long observation periods are needed to properly sample low-frequency processes that may also be important. The introduction of high-frequency (HF) radar measurements and regional wind models for coastal studies is changing this situation. Here we analyze synoptic, high-resolution surface winds andmore » currents in the Delaware Bay mouth over an eight-month period (October 2007 through May 2008). The surface currents were measured by two high-frequency radars while the surface winds were extracted from a data-assimilating regional wind model. To illustrate the utility of these monitoring tools we focus on two 45-day periods which previously were shown to present contrasting pictures of the circulation. One, the low-outflow period is from 1 October through 14 November 2007; the other is the high-outflow period from 3 March through 16 April 2008. The large-scale characteristics noted by previous workers are clearly corroborated. Specifically the M2 tide dominates the surface currents, and the Delaware Bay outflow plume is clearly evident in the low frequency currents. Several new aspects of the surface circulation were also identified. These include a map of the spatial variability of the M2 tide (validating an earlier model study), persistent low-frequency cross-mouth flow, and a rapid response of the surface currents to a changing wind field. However, strong wind episodes did not persist long enough to set up a sustained Ekman response.« less

A High Efficiency Boost Converter with MPPT Scheme for Low Voltage Thermoelectric Energy Harvesting

NASA Astrophysics Data System (ADS)

Guan, Mingjie; Wang, Kunpeng; Zhu, Qingyuan; Liao, Wei-Hsin

2016-11-01

Using thermoelectric elements to harvest energy from heat has been of great interest during the last decade. This paper presents a direct current-direct current (DC-DC) boost converter with a maximum power point tracking (MPPT) scheme for low input voltage thermoelectric energy harvesting applications. Zero current switch technique is applied in the proposed MPPT scheme. Theoretical analysis on the converter circuits is explored to derive the equations for parameters needed in the design of the boost converter. Simulations and experiments are carried out to verify the theoretical analysis and equations. A prototype of the designed converter is built using discrete components and a low-power microcontroller. The results show that the designed converter can achieve a high efficiency at low input voltage. The experimental efficiency of the designed converter is compared with a commercial converter solution. It is shown that the designed converter has a higher efficiency than the commercial solution in the considered voltage range.

Silicon Carbide Monofilament Reinforced Titanium Composites For Space Structures: A New Material Option

NASA Astrophysics Data System (ADS)

Kyle-Henney, Stephen; Flitcroft, Stephen; Shatwell, Robert; Gibbon, David; Voss, Gary; Harkness, Patrick

2012-07-01

Silicon carbide fibre reinforced titanium composite material has been in development since the 1980s initially for high temperature structures on hypersonic vehicles (HOTOL, NASP). Since then development has focused on military and civil aircraft. Development in the European Union has reached a level of maturity where it is again being considered for space applications. Current activities include pressure vessels and studies for launch vehicles and satellite applications. The paper provides background to the technology key performance characteristics current application work and future activities. The renewed interest in hypersonic vehicles has also picked up on the potential for lightweight metallic composites.

77 FR 2267 - Notice of Intent To Extend a Currently Approved Information Collection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-17

...: 05/31/2012. Type of Request: Extension of a currently approved information collection for three years... preparing a review they do not have a conflict-of-interest with a particular application and will maintain... applications and reviews but also panel discussions. On the Conflict-of-Interest and Confidentiality...

12 CFR 792.20 - What are the charges for each fee category?

Code of Federal Regulations, 2010 CFR

2010-01-01

... a use or purpose that furthers the commercial, trade, or profit interests of the requester or the... higher education, an institution of professional education, and an institution of vocational education... news means information that is about current events or that would be of current interest to the public...

Web 2.0 technologies for undergraduate and postgraduate medical education: an online survey.

PubMed

Sandars, J; Schroter, S

2007-12-01

To identify the current familiarity and use of Web 2.0 technologies by medical students and qualified medical practitioners, and to identify the barriers to its use for medical education. A semi-structured online questionnaire survey of 3000 medical students and 3000 qualified medical practitioners (consultants, general practitioners and doctors in training) on the British Medical Association's membership database. All groups had high familiarity, but low use, of podcasts. Ownership of digital media players was higher among medical students. There was high familiarity, but low use, of other Web 2.0 technologies except for high use of instant messaging and social networking by medical students. All groups stated that they were interested in using Web 2.0 technologies for education but there was lack of knowledge and skills in how to use these new technologies. There is an overall high awareness of a range of new Web 2.0 technologies by both medical students and qualified medical practitioners and high interest in its use for medical education. However, the potential of Web 2.0 technologies for undergraduate and postgraduate medical education will only be achieved if there is increased training in how to use this new approach.

Graduate Students' Interest in Immunology as a Discipline

ERIC Educational Resources Information Center

Kwarteng, Alexander; Frimpong, Michael; Sylverken, Augustina Angelina; Arthur, Yarhands D.; Ahuno, Samuel T.; Owusu-Dabo, Ellis

2017-01-01

Interest and motivation significantly influence achievement; however, interest in immunology remains to be determined. Using a structured questionnaire, the current study assessed for the first time interest in immunology among biomedical graduate students in Ghana after a one-week introduction to immunology course. Our results revealed that…

17 CFR 256.237 - Interest accrued.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Interest accrued. 256.237... COMPANY ACT OF 1935 7. Current and Accrued Liabilities § 256.237 Interest accrued. This account shall include the amount of interest accrued on all liabilities of the service company. Supporting records shall...

17 CFR 256.237 - Interest accrued.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Interest accrued. 256.237... COMPANY ACT OF 1935 7. Current and Accrued Liabilities § 256.237 Interest accrued. This account shall include the amount of interest accrued on all liabilities of the service company. Supporting records shall...

Plasma physics and related challenges of millimeter-wave-to-terahertz and high power microwave generationa)

NASA Astrophysics Data System (ADS)

Booske, John H.

2008-05-01

Homeland security and military defense technology considerations have stimulated intense interest in mobile, high power sources of millimeter-wave (mmw) to terahertz (THz) regime electromagnetic radiation, from 0.1 to 10THz. While vacuum electronic sources are a natural choice for high power, the challenges have yet to be completely met for applications including noninvasive sensing of concealed weapons and dangerous agents, high-data-rate communications, high resolution radar, next generation acceleration drivers, and analysis of fluids and condensed matter. The compact size requirements for many of these high frequency sources require miniscule, microfabricated slow wave circuits. This necessitates electron beams with tiny transverse dimensions and potentially very high current densities for adequate gain. Thus, an emerging family of microfabricated, vacuum electronic devices share many of the same plasma physics challenges that are currently confronting "classic" high power microwave (HPM) generators including long-life bright electron beam sources, intense beam transport, parasitic mode excitation, energetic electron interaction with surfaces, and rf air breakdown at output windows. The contemporary plasma physics and other related issues of compact, high power mmw-to-THz sources are compared and contrasted to those of HPM generation, and future research challenges and opportunities are discussed.

Ex vivo identification and characterization of a population of CD13(high) CD105(+) CD45(-) mesenchymal stem cells in human bone marrow.

PubMed

Muñiz, Carmen; Teodosio, Cristina; Mayado, Andrea; Amaral, Ana Teresa; Matarraz, Sergio; Bárcena, Paloma; Sanchez, Maria Luz; Alvarez-Twose, Iván; Diez-Campelo, María; García-Montero, Andrés C; Blanco, Juan F; Del Cañizo, Maria Consuelo; del Pino Montes, Javier; Orfao, Alberto

2015-09-07

Mesenchymal stem cells (MSCs) are multipotent cells capable of self-renewal and multilineage differentiation. Their multipotential capacity and immunomodulatory properties have led to an increasing interest in their biological properties and therapeutic applications. Currently, the definition of MSCs relies on a combination of phenotypic, morphological and functional characteristics which are typically evaluated upon in vitro expansion, a process that may ultimately lead to modulation of the immunophenotypic, functional and/or genetic features of these cells. Therefore, at present there is great interest in providing markers and phenotypes for direct in vivo and ex vivo identification and isolation of MSCs. Multiparameter flow cytometry immunophenotypic studies were performed on 65 bone marrow (BM) samples for characterization of CD13(high) CD105(+) CD45(-) cells. Isolation and expansion of these cells was performed in a subset of samples in parallel to the expansion of MSCs from mononuclear cells following currently established procedures. The protein expression profile of these cells was further assessed on (paired) primary and in vitro expanded BM MSCs, and their adipogenic, chondrogenic and osteogenic differentiation potential was also determined. Our results show that the CD13(high) CD105(+) CD45(-) immunophenotype defines a minor subset of cells that are systematically present ex vivo in normal/reactive BM (n = 65) and that display immunophenotypic features, plastic adherence ability, and osteogenic, adipogenic and chondrogenic differentiation capacities fully compatible with those of MSCs. In addition, we also show that in vitro expansion of these cells modulates their immunophenotypic characteristics, including changes in the expression of markers currently used for the definition of MSCs, such as CD105, CD146 and HLA-DR. BM MSCs can be identified ex vivo in normal/reactive BM, based on a robust CD13(high) CD105(+) and CD45(-) immunophenotypic profile. Furthermore, in vitro expansion of these cells is associated with significant changes in the immunophenotypic profile of MSCs.

In the Field Feasibility of a Simple Method to Check for Radioactivity in Commodities and in the Environment

PubMed Central

Alessandri, Stefano

2017-01-01

Introduction: Some release of radionuclides into the environment can be expected from the growing number of nuclear plants, either in or out of service. The citizen and the big organization could be both interested in simple and innovative methods for checking the radiological safety of their environment and of commodities, starting from foods. Methods: In this work three methods to detect radioactivity are briefly compared  focusing on the most recent, which converts a smartphone into a radiation counter. Results: The results of a simple sensitivity test are presented showing the measure of the activity of reference sources put at different distances from each sensor. Discussion: The three methods are discussed in terms of availability, technology, sensitivity, resolution and usefulness. The reported results can be usefully transferred into a radiological emergency scenario and they also offer some interesting implication for our current everyday life, but show that the hardware of the tested smart-phone can detect only high levels of radioactivity. However the technology could be interesting to build a working detection and measurement chain which could start from a diffused and networked first screening before the final high resolution analysis. PMID:28744409

Childhood and Current Autistic Features in Adolescents with Schizotypal Personality Disorder

PubMed Central

Esterberg, Michelle L.; Trotman, Hanan D.; Brasfield, Joy L.; Compton, Michael T.; Walker, Elaine F.

2008-01-01

The diagnostic boundaries between autistic- and schizophrenia-spectrum disorders have varied over the years, and some overlap in diagnostic criteria persists. The present study examined childhood and current signs of autistic disorder (AD) in adolescents with schizotypal personality disorder (SPD) or other personality disorders, as well as healthy controls. A structured interview was administered to rate participants’ current symptoms. Participants’ guardians were interviewed with the Autism Diagnostic Inventory-Revised (ADI-R), a clinical assessment of childhood and current autistic signs. Compared to both the other personality-disordered and healthy groups, adolescents with SPD were rated as having significantly more impairment on childhood and current social functioning, and having more unusual interests and behaviors. For the entire sample, impaired childhood social functioning and unusual interests and behaviors were associated with higher negative symptom scores. Current impairments in social functioning, unusual interests and behaviors, and communication were also linked with greater negative symptoms. However, neither childhood nor current autistic features significantly predicted later conversion to an Axis I psychotic disorder over the course of three years of follow-up. The findings indicate that past and current autistic signs are more common in adolescents with SPD, but neither current nor childhood autistic features are linked with conversion to psychosis. PMID:18554872

[Asperger syndrome: evolution of the concept and current clinical data].

PubMed

Aussilloux, C; Baghdadli, A

2008-05-01

Although Asperger syndrome is described by international classifications as a category of pervasive developmental disorder (PDD), its validity as a specific entity distinct from autistic disorders remains controversial. The syndrome, first described by Hans Asperger, could not be distinguished from high functioning autism (onset, symptoms, outcome...). However, international classifications propose a distinction between the two syndromes based on a delayed onset, the absence of speech delay, the presence of motor disorders and a better outcome in Asperger syndrome. This categorical differentiation is not confirmed by current studies and in the absence of biological markers, no clinical, neuropsychological or epidemiological criteria makes it possible to distinguish high functioning autism from Asperger syndrome. From a clinical perspective, it is nevertheless of interest to isolate Asperger syndrome from other autistic disorders to propose specific assessment and therapy.

Social inclusion facilitates risky mating behavior in men.

PubMed

Sacco, Donald F; Brown, Christina M; Young, Steven G; Bernstein, Michael J; Hugenberg, Kurt

2011-07-01

Although past research has reliably established unique effects of social exclusion on human cognition and behavior, the current research focuses on the unique effects of social inclusion. Recent evidence indicates that social inclusion leads to enhanced prioritization of reproductive interests. The current study extends these findings by showing that the pursuit of these inclusion-induced reproductive goals occurs in sex-specific ways. Across three experiments, social inclusion led men, but not women, to endorse riskier, more aggressive mating strategies compared to control and socially excluded participants. Specifically, included men were more likely to endorse sexual aggression (Experiment 1), high-risk mate poaching behaviors (Experiment 2), and high-risk mate retention tactics (Experiment 3). These results demonstrate that the experience of social inclusion can affect sex-differentiated preferences for risky mating strategies. © 2011 by the Society for Personality and Social Psychology, Inc

Toward superconducting critical current by design

DOE PAGES

Sadovskyy, Ivan A.; Jia, Ying; Leroux, Maxime; ...

2016-03-31

The interaction of vortex matter with defects in applied superconductors directly determines their current carrying capacity. Defects range from chemically grown nanostructures and crystalline imperfections to the layered structure of the material itself. The vortex-defect interactions are non-additive in general, leading to complex dynamic behavior that has proven difficult to capture in analytical models. With recent rapid progress in computational powers, a new paradigm has emerged that aims at simulation assisted design of defect structures with predictable ‘critical-current-by-design’: analogous to the materials genome concept of predicting stable materials structures of interest. We demonstrate the feasibility of this paradigm by combiningmore » large-scale time-dependent Ginzburg-Landau numerical simulations with experiments on commercial high temperature superconductor (HTS) containing well-controlled correlated defects.« less

The Self-Assembly of DNA Nanostructures for use as Organizing Templates

NASA Astrophysics Data System (ADS)

Samec, Timothy; Cholewinski, Mitchell; Reamer, Nickalas; Reardon, Michael; Ford, Arlene

There is growing interest in the self-assembling capabilities of DNA to create functional nanodevices for use in cancer detection and treatment. One important reason for this interest is that DNA nanostructures are highly programmable molecules. This means that these structures allow for increased stability and control when designing biomacromolecules via adhesion of plasmonic nanoparticles and other similar materials. Our current work reports on the procedure and construction of hexagonal two-dimensional DNA lattice structures using three specific DNA single strands. We also reflect on several barriers that were presented during fabrication as well as the adaptations made to overcome the aforementioned barriers by improving the quality, reproducibility, and yield of the hexagonal two-dimensional DNA lattice as organizing templates.

Luminescence and scintillation properties of XPO4:Nd3+ (X = Y, Lu, Sc, La) crystals

NASA Astrophysics Data System (ADS)

Makowski, Michał; Witkowski, Marcin E.; Drozdowski, Winicjusz; Wojtowicz, Andrzej J.; Wisniewski, Krzysztof; Boatner, Lynn A.

2018-05-01

Due to their very fast short-wavelength emission, neodymium-doped materials are a subject of current interest as potential scintillators. Although the initial reports regarding neodymium-doped orthophosphates (in crystalline form) and their scintillation properties appeared almost twenty years ago, they remain an interesting class of materials since there is no in-depth understanding of their fundamental scintillation mechanism. In the present research, we focus on the crystalline systems: XPO4:Nd3+, where X = Y, Lu, La, Sc. The pulse height, optical absorption, radioluminescence and photoluminescence spectra were investigated and are reported here for various temperatures from 10 to 350 K. Additionally, results of both low and high temperature thermoluminescence measurements are reported in this communication.

GENIUS: web server to predict local gene networks and key genes for biological functions.

PubMed

Puelma, Tomas; Araus, Viviana; Canales, Javier; Vidal, Elena A; Cabello, Juan M; Soto, Alvaro; Gutiérrez, Rodrigo A

2017-03-01

GENIUS is a user-friendly web server that uses a novel machine learning algorithm to infer functional gene networks focused on specific genes and experimental conditions that are relevant to biological functions of interest. These functions may have different levels of complexity, from specific biological processes to complex traits that involve several interacting processes. GENIUS also enriches the network with new genes related to the biological function of interest, with accuracies comparable to highly discriminative Support Vector Machine methods. GENIUS currently supports eight model organisms and is freely available for public use at http://networks.bio.puc.cl/genius . genius.psbl@gmail.com. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

Thickness-dependently enhanced photodetection performance of vertically grown SnS2 nanoflakes with large size and high production.

PubMed

Jia, Xiansheng; Tang, Chengchun; Pan, Ruhao; Long, Yun-Ze; Gu, Changzhi; Li, Junjie

2018-05-10

Photodetection based on Two-dimensional (2D) SnS2 has attracted a growing interest due to its superiority in response rate and responsivity, but high-quality growth and high performance photodetecting of 2D SnS2still face great challenges. Here, high-quality SnS2 nanoflakes with large-size and high-production are vertically grown on Si substrate by a modified CVD method, having an average size of 30 m with different thicknesses. Then a single SnS2 nanoflake-based phototransistor was fabricated to obtain a high current on/off ratio of 107 and excellent performances in photodetection, including fast response rates, low dark current, high responsivity and detectivity. Specifically, the SnS2 nanoflakes show the thickness-dependent photodetection capability and the highest responsivity of 354.4 A W-1 is obtained at the average thickness of 100.5 nm. A sensitized process using HfO2 nanolayer can further enhance the responsivity up to 1922 A W-1. Our work provides an efficient path to select SnS2 crystal samples with the optimal thickness as promising candidates for high-performance optoelectronic applications.

High Performance Amplifier Element Realization via MoS2/GaTe Heterostructures.

PubMed

Yan, Xiao; Zhang, David Wei; Liu, Chunsen; Bao, Wenzhong; Wang, Shuiyuan; Ding, Shijin; Zheng, Gengfeng; Zhou, Peng

2018-04-01

2D layered materials (2DLMs), together with their heterostructures, have been attracting tremendous research interest in recent years because of their unique physical and electrical properties. A variety of circuit elements have been made using mechanically exfoliated 2DLMs recently, including hard drives, detectors, sensors, and complementary metal oxide semiconductor field-effect transistors. However, 2DLM-based amplifier circuit elements are rarely studied. Here, the integration of 2DLMs with 3D bulk materials to fabricate vertical junction transistors with current amplification based on a MoS 2 /GaTe heterostructure is reported. Vertical junction transistors exhibit the typical current amplification characteristics of conventional bulk bipolar junction transistors while having good current transmission coefficients (α ∼ 0.95) and current gain coefficient (β ∼ 7) at room temperature. The devices provide new attractive prospects in the investigation of 2DLM-based integrated circuits based on amplifier circuits.

The atmospheric effects of stratospheric aircraft: A topical review

NASA Technical Reports Server (NTRS)

Johnston, Harold S.; Prather, M. J.; Watson, R. T.

1991-01-01

In the late 1960s the aircraft industry became interested in developing a fleet of supersonic transports (SSTs). Between 1972 and 1975, the Climatic Impact Assessment Program (CIAP) studied the possible environmental impact of SSTs. For environmental and economic reasons, the fleet of SSTs was not developed. The Upper Atmosphere Research Program (UARP) has recently undertaken the responsibility of directing scientific research needed to assess the atmospheric impact of supersonic transports. The UARP and the High-Speed Research Program asked Harold Johnston to review the current understanding of aircraft emissions and their effect on the stratosphere. Johnston and his colleagues have recently re-examined the SST problem using current models for stratospheric ozone chemistry. A unique view is given here of the current scientific issues and the lessons learned since the beginning of CIAP, and it links the current research program with the assessment process that began two years ago.

Can Direct Current Electrotherapy Be Used for Patients With Orthopedic Implants?

PubMed Central

Thaler, Evangeline; Korte, Holger

2017-01-01

Introduction: Although electrotherapy appears to have particularly interesting applications in the field of postoperative orthopedic rehabilitation, relatively little scientifically based research has been conducted in the area of electrotherapy with regard to safety involving patients with orthopedic implants. Method: Three electrotherapy forms were tested, such as high-volt stimulation (HVS), transcutaneous electric nerve stimulation (TENS), and galvanic current (GAL), using a model system containing a metal implant plate to evaluate whether heating in excess of 3°C would occur. Results: All changes in temperature for HVS, GAL, and TENS therapeutic electrical currents observed in our model system fall below the predefined 3°C. Conclusion: To the best of our knowledge, this is the first experimental based observation that prolonged exposure to a direct electrical current at therapeutic strength does not result in heating of metal titanium plates. PMID:28255511

High Performance Amplifier Element Realization via MoS2/GaTe Heterostructures

PubMed Central

Yan, Xiao; Zhang, David Wei; Liu, Chunsen; Bao, Wenzhong; Wang, Shuiyuan; Ding, Shijin; Zheng, Gengfeng

2018-01-01

Abstract 2D layered materials (2DLMs), together with their heterostructures, have been attracting tremendous research interest in recent years because of their unique physical and electrical properties. A variety of circuit elements have been made using mechanically exfoliated 2DLMs recently, including hard drives, detectors, sensors, and complementary metal oxide semiconductor field‐effect transistors. However, 2DLM‐based amplifier circuit elements are rarely studied. Here, the integration of 2DLMs with 3D bulk materials to fabricate vertical junction transistors with current amplification based on a MoS2/GaTe heterostructure is reported. Vertical junction transistors exhibit the typical current amplification characteristics of conventional bulk bipolar junction transistors while having good current transmission coefficients (α ∼ 0.95) and current gain coefficient (β ∼ 7) at room temperature. The devices provide new attractive prospects in the investigation of 2DLM‐based integrated circuits based on amplifier circuits. PMID:29721428

Nano spin-diodes using FePt-NDs with huge on/off current ratio at room temperature

PubMed Central

Makihara, Katsunori; Kato, Takeshi; Kabeya, Yuuki; Mitsuyuki, Yusuke; Ohta, Akio; Oshima, Daiki; Iwata, Satoshi; Darma, Yudi; Ikeda, Mitsuhisa; Miyazaki, Seiichi

2016-01-01

Spin transistors have attracted tremendous interest as new functional devices. However, few studies have investigated enhancements of the ON/OFF current ratio as a function of the electron spin behavior. Here, we found a significantly high spin-dependent current ratio—more than 102 at 1.5 V—when changing the relative direction of the magnetizations between FePt nanodots (NDs) and the CoPtCr-coated atomic force microscope (AFM) probe at room temperature. This means that ON and OFF states were achieved by switching the magnetization of the FePt NDs, which can be regarded as spin-diodes. The FePt magnetic NDs were fabricated by exposing a bi-layer metal stack to a remote H2 plasma (H2-RP) on ~1.7 nm SiO2/Si(100) substrates. The ultrathin bi-layers with a uniform surface coverage are changed drastically to NDs with an areal density as high as ~5 × 1011 cm−2. The FePt NDs exhibit a large perpendicular anisotropy with an out-of-plane coercivity of ~4.8 kOe, reflecting the magneto-crystalline anisotropy of (001) oriented L10 phase FePt. We also designed and fabricated double-stacked FePt-NDs with low and high coercivities sandwiched between an ultra-thin Si-oxide interlayer, and confirmed a high ON/OFF current ratio when switching the relative magnetization directions of the low and high coercivity FePt NDs. PMID:27615374

Access, interest, and attitudes toward electronic communication for health care among patients in the medical safety net.

PubMed

Schickedanz, Adam; Huang, David; Lopez, Andrea; Cheung, Edna; Lyles, C R; Bodenheimer, Tom; Sarkar, Urmimala

2013-07-01

Electronic and internet-based tools for patient-provider communication are becoming the standard of care, but disparities exist in their adoption among patients. The reasons for these disparities are unclear, and few studies have looked at the potential communication technologies have to benefit vulnerable patient populations. To characterize access to, interest in, and attitudes toward internet-based communication in an ethnically, economically, and linguistically diverse group of patients from a large urban safety net clinic network. Observational, cross-sectional study Adult patients (≥ 18 years) in six resource-limited community clinics in the San Francisco Department of Public Health (SFDPH) MAIN MEASURES: Current email use, interest in communicating electronically with health care professionals, barriers to and facilitators of electronic health-related communication, and demographic data-all self-reported via survey. Sixty percent of patients used email, 71 % were interested in using electronic communication with health care providers, and 19 % reported currently using email informally with these providers for health care. Those already using any email were more likely to express interest in using it for health matters. Most patients agreed electronic communication would improve clinic efficiency and overall communication with clinicians. A significant majority of safety net patients currently use email, text messaging, and the internet, and they expressed an interest in using these tools for electronic communication with their medical providers. This interest is currently unmet within safety net clinics that do not offer a patient portal or secure messaging. Tools such as email encounters and electronic patient portals should be implemented and supported to a greater extent in resource-poor settings, but this will require tailoring these tools to patients' language, literacy level, and experience with communication technology.

Factors influencing the choice of a career in food-animal practice among recent graduates and current students of Texas A&M University, College of Veterinary Medicine.

PubMed

Lenarduzzi, Roland; Sheppard, Guy A; Slater, Margaret R

2009-01-01

Concerns about a shortage of large and mixed-animal veterinarians have been discussed in the profession. To better understand veterinary career choices among currently enrolled veterinary students (classes of 2007-2010) and recent graduate veterinarians in Texas (classes of 2002-2006), an online survey was developed. The objectives were to examine: (1) the respondents' backgrounds, demographic data, and experiences; (2) the respondents' working conditions and rural lifestyle considerations; (3) the respondents' perceptions of large/mixed-animal practice; and (4) the factors that have influenced respondents' career choices. The response rate was 37% (390/1,042). Overall, 72% of students and 55% of recent graduates were interested in large/mixed-animal practice. More than 70% of respondents indicated that veterinary practitioners had the strongest personal influence on career choices. Respondents who were no longer interested in large/mixed-animal practice, or who had never been interested, reported no experience with large animals (42% and 64%, respectively) as the most common reason for their lack of interest. Previous and current interest in large/mixed-animal practice were associated with working in a large/mixed-animal practice, any agricultural experience, and working for at least 6 months on a farm or ranch. Any 4-H experience increased the likelihood of previous interest, while being married decreased the likelihood of current interest. Student contact with practitioners (82%) and financial considerations (77%) were most commonly cited as factors that would make a career in large/mixed-animal practice more attractive. Rural lifestyle drawbacks influenced respondents' career choices. Many forms of agricultural experience may expose and encourage students to consider large/mixed-animal practice.

Smart Distributed Sensor Fields: Algorithms for Tactical Sensors

DTIC Science & Technology

2013-12-23

ranging from detecting, identifying, localizing/tracking interesting events, discarding irrelevant data, to providing actionable intelligence currently...tracking interesting events, discarding irrelevant data, to providing actionable intelligence currently requires significant human super- vision. Human...view of the overall system. The main idea is to reduce the problem to the relevant data, and then reason intelligently over that data. This process

Mind Wandering and Reading Comprehension: Examining the Roles of Working Memory Capacity, Interest, Motivation, and Topic Experience

ERIC Educational Resources Information Center

Unsworth, Nash; McMillan, Brittany D.

2013-01-01

Individual differences in mind wandering and reading comprehension were examined in the current study. In particular, individual differences in mind wandering, working memory capacity, interest in the current topic, motivation to do well on the task, and topic experience and their relations with reading comprehension were examined in the current…

43 CFR 5.12 - How are terms defined in this subpart?

Code of Federal Regulations, 2013 CFR

2013-10-01

.... Representative of the news media means any person or entity that gathers information of potential interest to a... as vehicles, boats, articles of clothing, and food and beverage products, placed on agency lands so... information that is about current events or that would be of current interest to the public, gathered by news...

43 CFR 5.12 - How are terms defined in this subpart?

Code of Federal Regulations, 2014 CFR

2014-10-01

.... Representative of the news media means any person or entity that gathers information of potential interest to a... as vehicles, boats, articles of clothing, and food and beverage products, placed on agency lands so... information that is about current events or that would be of current interest to the public, gathered by news...

Gender, Prior Knowledge, Interest, and Experience in Electricity and Conceptual Change Text Manipulations in Learning about Direct Current.

ERIC Educational Resources Information Center

Chambers, Sharon K.; Andre, Thomas

1997-01-01

Presents a study that investigated relationships between gender, interest, and experience in electricity. Also explored the effect of conceptual change text manipulations on learning fundamental concepts of direct current. Suggests that conceptual change text manipulations are likely to be effective for both men and women. Contains 57 references.…

49 CFR 1017.14 - Interest, penalties, and administrative costs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... OFFSET FROM INDEBTED GOVERNMENT AND FORMER GOVERNMENT EMPLOYEES § 1017.14 Interest, penalties, and administrative costs. (a) The rate of interest assessed shall be the rate of the current value of funds to the U... of interest can be assessed if the Board can reasonably determine that a higher rate is necessary to...

7 CFR 792.10 - Late payment interest, penalty and administrative charges.

Code of Federal Regulations, 2010 CFR

2010-01-01

... State and local governments. Interest on debts owed by such entities shall be charged to the extent... debts. The late payment interest rate shall be equal to the higher of the Treasury Department's current... Prompt Payment Act was chosen as an alternative rate to ensure that the Government would recoup interest...

Restoring longleaf pine (Pinus palustris Mill.) in loblolly pine (Pinus taeda L.) stands: Effects of restoration treatments on natural loblolly pine regeneration

Treesearch

Ben Knapp; Wang Geoff; Huifeng Hu; Joan Walker; Carsyn Tennant

2011-01-01

Historical land use and management practices in the southeastern United States have resulted in the dominance of loblolly pine on many upland sites that historically were occupied by longleaf pine. There is currently much interest in restoring high quality longleaf pine habitats to such areas, but managers may also desire the retention of some existing canopy trees to...

Analytical techniques for identification and study of organic matter in returned lunar samples

NASA Technical Reports Server (NTRS)

Burlingame, A. L.

1974-01-01

The results of geochemical research are reviewed. Emphasis is placed on the contribution of mass spectrometric data to the solution of specific structural problems. Information on the mass spectrometric behavior of compounds of geochemical interest is reviewed and currently available techniques of particular importance to geochemistry, such as gas chromatograph-mass spectrometer coupling, modern sample introduction methods, and computer application in high resolution mass spectrometry, receive particular attention.

Ocean Science Video Challenge Aims to Improve Science Communication

NASA Astrophysics Data System (ADS)

Showstack, Randy

2013-10-01

Given today's enormous management and protection challenges related to the world's oceans, a new competition calls on ocean scientists to effectively communicate their research in videos that last up to 3 minutes. The Ocean 180 Video Challenge, named for the number of seconds in 3 minutes, aims to improve ocean science communication while providing high school and middle school teachers and students with new and interesting educational materials about current science topics.

Delivery Issues in the Day Care Debate. Occasional Papers in Education: Paper No. 2 - Policy Studies of the Early Childhood Planning Project.

ERIC Educational Resources Information Center

McGee, Maureen

The question of who should provide day care services is an unresolved issue in the current day care debate and a topic now on the national agenda because it is the common concern of a constellation of diverse, highly motivated interest groups. Motivation for extending day care in the United States stems from several factors: among these are the…

Payers' Perspectives: Health Economics Outcomes in Managed Care

PubMed Central

Bankhead, Charles

2015-01-01

The following summaries represent a sample of the many studies presented at the 27th Annual Meeting of the Academy of Managed Care Pharmacy (AMCP), April 7–10, 2015, in San Diego, CA. These summaries highlight some of the main trends in the current US healthcare, reflecting the impact of real-world, evidence-based issues of high interest for payers, employers, drug manufacturers, providers, patients, and other healthcare stakeholders. PMID:26085902

A national survey of policies on disclosure of conflicts of interest in biomedical research

NASA Technical Reports Server (NTRS)

McCrary, S. V.; Anderson, C. B.; Jakovljevic, J.; Khan, T.; McCullough, L. B.; Wray, N. P.; Brody, B. A.

2000-01-01

BACKGROUND: Conflicts of interest pose a threat to the integrity of scientific research. The current regulations of the U.S. Public Health Service and the National Science Foundation require that medical schools and other research institutions report the existence of conflicts of interest to the funding agency but allow the institutions to manage conflicts internally. The regulations do not specify how to do so. METHODS: We surveyed all medical schools (127) and other research institutions (170) that received more than $5 million in total grants annually from the National Institutes of Health or the National Science Foundation; 48 journals in basic science and clinical medicine; and 17 federal agencies in order to analyze their policies on conflicts of interest. RESULTS: Of the 297 institutions, 250 (84 percent) responded by March 2000, as did 47 of the 48 journals and 16 of the 17 federal agencies. Fifteen of the 250 institutions (6 percent)--5 medical schools and 10 other research institutions--reported that they had no policy on conflicts of interest. Among the institutions that had policies, there was marked variation in the definition and management of conflicts. Ninety-one percent had policies that adhered to the federal threshold for disclosure ($10,000 in annual income or equity in a relevant company or 5 percent ownership), and 9 percent had policies that exceeded the federal guidelines. Only 8 percent had policies requiring disclosure to funding agencies, only 7 percent had such policies regarding journals, and only 1 percent had policies requiring the disclosure of information to the relevant institutional review boards or to research subjects. Twenty journals (43 percent) reported that they had policies requiring disclosure of conflicts of interest. Only four federal agencies had policies that explicitly addressed conflicts of interest in extramural research, and all but one of the agencies relied primarily on institutional discretion. CONCLUSIONS: There is substantial variation among policies on conflicts of interest at medical schools and other research institutions. This variation, combined with the fact that many scientific journals and funding agencies do not require disclosure of conflicts of interest, suggests that the current standards may not be adequate to maintain a high level of scientific integrity.

[Development of antibody medicines by bio-venture: lesson from license negotiations with mega pharmacies].

PubMed

Takada, Kenzo

2013-01-01

The current method of antibody production is mainly the hybridoma method, in which mice are immunized with an excess amount of antigen for a short period to promote activation and proliferation of B-lymphocytes producing the antibodies of interest. Because of the excess antigen, those producing low-affinity antibodies are activated. In contrast, human blood B-lymphocytes are activated through natural immune reactions, such as the reaction to infection. B-lymphocytes are stimulated repeatedly with a small amount of antigen, and thus only those producing high-affinity antibodies are activated. Consequently, the lymphocytes producing the high-affinity antibodies are accumulated in human blood. Therefore, human lymphocytes are an excellent source of high-affinity antibodies. Evec, Inc. has established a unique method to produce high-affinity antibodies from human lymphocytes using Epstein-Barr virus (EBV), which induces the proliferation of B-lymphocytes. The method first induces the proliferation of B-lymphocytes from human blood using EBV, and then isolates those producing the antibodies of interest. The key features of the Evec technique are: 1) development of a lymphocyte library consisting of 150 donors' lymphocytes from which donors suited to develop the antibodies of interest can be selected in 4 days; and 2) development of a sorting method and cell microarray method for selecting lymphocyte clones producing the target antibodies. Licensing agreements have been concluded with European and Japanese pharmaceutical companies for two types of antibody. This paper describes Evec's antibody technology and experience in license negotiations with Mega Pharmacies.

A highly crystalline single Au wire network as a high temperature transparent heater

NASA Astrophysics Data System (ADS)

Rao, K. D. M.; Kulkarni, Giridhar U.

2014-05-01

A transparent conductor which can generate high temperatures finds important applications in optoelectronics. In this article, a wire network made of Au on quartz is shown to serve as an effective high temperature transparent heater. The heater has been fabricated by depositing Au onto a cracked sacrificial template. The highly interconnected Au wire network thus formed exhibited a transmittance of ~87% in a wide spectral range with a sheet resistance of 5.4 Ω □-1. By passing current through the network, it could be joule heated to ~600 °C within a few seconds. The extraordinary thermal performance and stability owe much to the seamless junctions present in the wire network. Furthermore, the wire network gets self-annealed through joule heating as seen from its increased crystallinity. Interestingly, both transmittance and sheet resistance improved following annealing to 92% and 3.2 Ω □-1, respectively. A transparent conductor which can generate high temperatures finds important applications in optoelectronics. In this article, a wire network made of Au on quartz is shown to serve as an effective high temperature transparent heater. The heater has been fabricated by depositing Au onto a cracked sacrificial template. The highly interconnected Au wire network thus formed exhibited a transmittance of ~87% in a wide spectral range with a sheet resistance of 5.4 Ω □-1. By passing current through the network, it could be joule heated to ~600 °C within a few seconds. The extraordinary thermal performance and stability owe much to the seamless junctions present in the wire network. Furthermore, the wire network gets self-annealed through joule heating as seen from its increased crystallinity. Interestingly, both transmittance and sheet resistance improved following annealing to 92% and 3.2 Ω □-1, respectively. Electronic supplementary information (ESI) available: Optical micrographs, EDAX, XRD, SEM and TEM images of Au metal wires. See DOI: 10.1039/c4nr00869c

On the skill of various ensemble spread estimators for probabilistic short range wind forecasting

NASA Astrophysics Data System (ADS)

Kann, A.

2012-05-01

A variety of applications ranging from civil protection associated with severe weather to economical interests are heavily dependent on meteorological information. For example, a precise planning of the energy supply with a high share of renewables requires detailed meteorological information on high temporal and spatial resolution. With respect to wind power, detailed analyses and forecasts of wind speed are of crucial interest for the energy management. Although the applicability and the current skill of state-of-the-art probabilistic short range forecasts has increased during the last years, ensemble systems still show systematic deficiencies which limit its practical use. This paper presents methods to improve the ensemble skill of 10-m wind speed forecasts by combining deterministic information from a nowcasting system on very high horizontal resolution with uncertainty estimates from a limited area ensemble system. It is shown for a one month validation period that a statistical post-processing procedure (a modified non-homogeneous Gaussian regression) adds further skill to the probabilistic forecasts, especially beyond the nowcasting range after +6 h.

Progress in speckle-shift strain measurement

NASA Technical Reports Server (NTRS)

Lant, Christian T.; Barranger, John P.; Oberle, Lawrence G.; Greer, Lawrence C., III

1991-01-01

The Instrumentation and Control Technology Division of the Lewis Research Center has been developing an in-house capability to make one dimensional and two dimensional optical strain measurements on high temperature test specimens. The measurements are based on a two-beam speckle-shift technique. The development of composite materials for use in high temperature applications is generating interest in using the speckle-shift technique to measure strains on small diameter fibers and wires of various compositions. The results of preliminary speckle correlation tests on wire and fiber specimens are covered, and the advanced system currently under development is described.

Features of polar cusp electron precipitation associated with a large magnetic storm

NASA Technical Reports Server (NTRS)

Berko, F. W.

1974-01-01

Measurements of precipitating electrons made by the OGO-4 satellite reveal several interesting phenomena in the polar cusp. Extremely high fluxes of 0.7 keV electrons were observed in the polar cusp ninety minutes following the sudden commencement of a very large magnetic storm. Structured, fairly high fluxes of 7.3 keV electrons were also observed in the cusp region, accompanied by very strong search coil magnetometer fluctuations, indicative of strong field-aligned currents. The observations confirm previously reported latitudinal shifts in the location of the polar cusp in response to southward interplanetary magnetic fields.

High power bipolar lead-acid batteries

NASA Technical Reports Server (NTRS)

Halpert, Gerald; Attia, Alan

1991-01-01

The Jet Propulsion Laboratory (JPL), with interest in advanced energy storage systems, is involved in the development of a unique lead acid battery design. This battery utilizes the same combination of lead and lead dioxide active materials present in the automobile starting battery. However, it can provide 2 to 10 times the power while minimizing volume and weight. The typical starting battery is described as a monopolar type using one current collector for both the positive and negative plate of adjacent cells. Specific power as high as 2.5 kW/kg was projected for 30 second periods with as many as 2000 recharge cycles.

Did Janet Frame have high-functioning autism?

PubMed

Abrahamson, Sarah

2007-10-12

Janet Frame (1924-2004) was one of New Zealand's most well-known authors and unusual personalities. Her formal psychiatric diagnosis, however, has not been clear. Some have suggested that she was simply "different". This paper proposes that there is a name for her difference: high-functioning autism. The features of this condition apparent on analysis of her autobiographies are examined. Janet Frame was an interesting example of what may be achieved by those with strong autistic features. It is to be hoped that current and future generations of New Zealanders with autism spectrum disorders are recognised early and given appropriate advice.

BBU design of linear induction accelerator cells for radiography application

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shang, C.C.; Chen, Y.J.; Gaporaso, G.J.

1997-05-06

There is an ongoing effort to develop accelerating modules for high-current electron accelerators for advanced radiography application. Accelerating modules with low beam-cavity coupling impedances along with gap designs with acceptable field stresses comprise a set of fundamental design criteria. We examine improved cell designs which have been developed for accelerator application in several radiographic operating regimes. We evaluate interaction impedances, analyze the effects of beam structure coupling on beam dynamics (beam break-up instability and corkscrew motion). We also provide estimates of coupling through interesting new high-gradient insulators and evaluate their potential future application in induction cells.

NASA Astrophysics Data System (ADS)

Tube to tube-sheet joints in heat exchangers are currently welded by the orbital TIG process characterized by very high quality of the weld beads and good repeatability. However, due to high number of welds, a reduction in the welding cycle time would have an interesting impact on manufacturing costs and delays and laser welding technology is aimed to improve this factor. The main disadvantage is the positioning accuracy required by the laser welding process since beam deviations from real joint cause lack of penetration. It is expected that the Orbital laser welding head developed under the European project ORBITAL will avoid this drawback.

Directed area search using socio-biological vision algorithms and cognitive Bayesian reasoning

NASA Astrophysics Data System (ADS)

Medasani, S.; Owechko, Y.; Allen, D.; Lu, T. C.; Khosla, D.

2010-04-01

Volitional search systems that assist the analyst by searching for specific targets or objects such as vehicles, factories, airports, etc in wide area overhead imagery need to overcome multiple problems present in current manual and automatic approaches. These problems include finding targets hidden in terabytes of information, relatively few pixels on targets, long intervals between interesting regions, time consuming analysis requiring many analysts, no a priori representative examples or templates of interest, detecting multiple classes of objects, and the need for very high detection rates and very low false alarm rates. This paper describes a conceptual analyst-centric framework that utilizes existing technology modules to search and locate occurrences of targets of interest (e.g., buildings, mobile targets of military significance, factories, nuclear plants, etc.), from video imagery of large areas. Our framework takes simple queries from the analyst and finds the queried targets with relatively minimum interaction from the analyst. It uses a hybrid approach that combines biologically inspired bottom up attention, socio-biologically inspired object recognition for volitionally recognizing targets, and hierarchical Bayesian networks for modeling and representing the domain knowledge. This approach has the benefits of high accuracy, low false alarm rate and can handle both low-level visual information and high-level domain knowledge in a single framework. Such a system would be of immense help for search and rescue efforts, intelligence gathering, change detection systems, and other surveillance systems.

High-energy astrophysics and the search for sources of gravitational waves

NASA Astrophysics Data System (ADS)

O'Brien, P. T.; Evans, P.

2018-05-01

The dawn of the gravitational-wave (GW) era has sparked a greatly renewed interest into possible links between sources of high-energy radiation and GWs. The most luminous high-energy sources-gamma-ray bursts (GRBs)-have long been considered as very likely sources of GWs, particularly from short-duration GRBs, which are thought to originate from the merger of two compact objects such as binary neutron stars and a neutron star-black hole binary. In this paper, we discuss: (i) the high-energy emission from short-duration GRBs; (ii) what other sources of high-energy radiation may be observed from binary mergers; and (iii) how searches for high-energy electromagnetic counterparts to GW events are performed with current space facilities. While current high-energy facilities, such as Swift and Fermi, play a crucial role in the search for electromagnetic counterparts, new space missions will greatly enhance our capabilities for joint observations. We discuss why such facilities, which incorporate new technology that enables very wide-field X-ray imaging, are required if we are to truly exploit the multi-messenger era. This article is part of a discussion meeting issue `The promises of gravitational-wave astronomy'.

High-energy astrophysics and the search for sources of gravitational waves.

PubMed

O'Brien, P T; Evans, P

2018-05-28

The dawn of the gravitational-wave (GW) era has sparked a greatly renewed interest into possible links between sources of high-energy radiation and GWs. The most luminous high-energy sources-gamma-ray bursts (GRBs)-have long been considered as very likely sources of GWs, particularly from short-duration GRBs, which are thought to originate from the merger of two compact objects such as binary neutron stars and a neutron star-black hole binary. In this paper, we discuss: (i) the high-energy emission from short-duration GRBs; (ii) what other sources of high-energy radiation may be observed from binary mergers; and (iii) how searches for high-energy electromagnetic counterparts to GW events are performed with current space facilities. While current high-energy facilities, such as Swift and Fermi, play a crucial role in the search for electromagnetic counterparts, new space missions will greatly enhance our capabilities for joint observations. We discuss why such facilities, which incorporate new technology that enables very wide-field X-ray imaging, are required if we are to truly exploit the multi-messenger era.This article is part of a discussion meeting issue 'The promises of gravitational-wave astronomy'. © 2018 The Author(s).

Perspectives on population growth.

PubMed

1996-09-01

Assume that everyone has the same information on population growth. There are many different opinions on what that information means and what should be done about it. Some people worry about current rates of growth, especially in the context of growing per capita consumption, and believe that all reasonable steps should be taken to reduce rates and stabilize population size. Others believe that growing populations can be accommodated by reducing consumption in rich countries, that technological progress will supply the new resources needed, that the development needed to support a larger population can be sustained, that large population size fosters prosperity, or that birth rates are falling and current growth is just temporary. These are all valid positions worthy of at least debate. Interest groups commonly acknowledgement population growth as a significant issue, but offer no response to it. Sometimes the issue goes unrecognized because it conflicts with a more highly valued personal agenda item. Finally, some responses come from confusion and anger rather than reasoning or self-interest. The proponents of these latter arguments bring nothing constructive to the debate.

Investigation of different anode materials for aluminium rechargeable batteries

NASA Astrophysics Data System (ADS)

Muñoz-Torrero, David; Leung, Puiki; García-Quismondo, Enrique; Ventosa, Edgar; Anderson, Marc; Palma, Jesús; Marcilla, Rebeca

2018-01-01

In order to shed some light into the importance of the anodic reaction in reversible aluminium batteries, we investigate here the electrodeposition of aluminium in an ionic liquid electrolyte (BMImCl-AlCl3) using different substrates. We explore the influence of the type of anodic material (aluminium, stainless steel and carbon) and its 3D geometry on the reversibility of the anodic reaction by cyclic voltammetry (CV) and galvanostatic charge-discharge. The shape of the CVs confirms that electrodeposition of aluminium was feasible in the three materials but the highest peak currents and smallest peak separation in the CV of the aluminium anode suggested that this material was the most promising. Interestingly, carbon-based substrates appeared as an interesting alternative due to the high peak currents in CV, moderate overpotentials and dual role as anode and cathode. 3D substrates such as fiber-based carbon paper and aluminium mesh showed significantly smaller overpotentials and higher efficiencies for Al reaction suggesting that the use of 3D substrates in full batteries might result in enhanced power. This is corroborated by polarization testing of full Al-batteries.

The impact of sea surface currents in wave power potential modeling

NASA Astrophysics Data System (ADS)

Zodiatis, George; Galanis, George; Kallos, George; Nikolaidis, Andreas; Kalogeri, Christina; Liakatas, Aristotelis; Stylianou, Stavros

2015-11-01

The impact of sea surface currents to the estimation and modeling of wave energy potential over an area of increased economic interest, the Eastern Mediterranean Sea, is investigated in this work. High-resolution atmospheric, wave, and circulation models, the latter downscaled from the regional Mediterranean Forecasting System (MFS) of the Copernicus marine service (former MyOcean regional MFS system), are utilized towards this goal. The modeled data are analyzed by means of a variety of statistical tools measuring the potential changes not only in the main wave characteristics, but also in the general distribution of the wave energy and the wave parameters that mainly affect it, when using sea surface currents as a forcing to the wave models. The obtained results prove that the impact of the sea surface currents is quite significant in wave energy-related modeling, as well as temporally and spatially dependent. These facts are revealing the necessity of the utilization of the sea surface currents characteristics in renewable energy studies in conjunction with their meteo-ocean forecasting counterparts.

Screening homeless youth for histories of abuse: prevalence, enduring effects, and interest in treatment.

PubMed

Keeshin, Brooks R; Campbell, Kristine

2011-06-01

To identify the incidence of self-reported physical and sexual child abuse among homeless youth, the self-perceived effects of past abuse, and current interest in treatment for past abuse among homeless youth with histories of abuse. Homeless and street-involved persons aged 18-23 filled out a questionnaire and participated in a structured assessment of histories of abuse, tobacco use and substance abuse. Sixty-four homeless youth in Salt Lake City, Utah completed the study, 43 males and 21 females. Eighty-four percent screened positive for childhood physical and/or sexual abuse occurring before the age of 18; 42% screened positive for both physical and sexual abuse; 72% reported still being affected by their abuse. Among all abuse victims, 44% were interested in treatment for their abuse history and 62% of homeless youth who reported still being affected by their abuse were interested in treatment. Individuals were more likely to be interested in treatment if they were female, had not completed high school or had been previously asked about family dysfunction. Many victims who declined treatment offered spontaneous insight into their decision. Interest in treatment was similar to interest in treatment for other behaviors such as smoking and substance abuse. Histories of abuse are common among homeless youth. A majority of those reporting a history of abuse are still affected by their abuse. Interest in treatment for a history of abuse was comparable to interest in treatment for other morbidities in the homeless youth population such as tobacco use and substance abuse. Our finding that homeless youth continue to be impacted by their abuse and are interested in treatment should prompt more screening for histories of abuse. Copyright © 2011 Elsevier Ltd. All rights reserved.

Do Emotions Spark Interest in Alternative Tobacco Products?

PubMed

Popova, Lucy; So, Jiyeon; Sangalang, Angeline; Neilands, Torsten B; Ling, Pamela M

2017-08-01

Exposure to advertisements for tobacco products and tobacco warning labels evokes emotions. This study evaluated the association of discrete positive and negative emotions with interest in alternative tobacco products. In 2013, 1,226 U.S. adult nonsmokers and current smokers viewed advertisements for moist snuff, snus, and electronic cigarettes (e-cigarettes) with various warning labels and then indicated their emotional responses in terms of anger, anxiety, sadness, guilt, disgust, discouragement, hope, and contentment. Outcomes were openness to using moist snuff, snus, and e-cigarettes in the future and interest in a free sample of each product. Data were analyzed in 2016. Hope was positively associated with openness and interest across all alternative tobacco products as was contentment for moist snuff and snus. Anger was negatively associated with openness to moist snuff and e-cigarettes, disgust negatively to moist snuff and snus, and anxiety negatively to e-cigarettes. Being a current smoker, ever trying a corresponding product, being male, and younger age were associated with greater openness to and interest in moist snuff and snus. For e-cigarettes, being a current smoker, ever trying e-cigarettes, and being female were associated with greater openness, and being a current smoker was associated with greater odds of selecting a free sample. Positive emotions, particularly hope, were consistently positively associated with interest in alternative tobacco products. Hope is widely used by tobacco and e-cigarette companies to advertise their products. Antitobacco messages should aim to lower hope associated with tobacco products but increase hope for cessation or life without tobacco.

Impact of the new european paediatric regulatory framework on ethics committees: overview and perspectives.

PubMed

Altavilla, A; Manfredi, C; Baiardi, P; Dehlinger-Kremer, M; Galletti, P; Pozuelo, A Alemany; Chaplin, J; Ceci, A

2012-01-01

To evaluate the impact of the new European paediatric regulatory framework on the activities of Ethics Committees operating in Europe and to assess their involvement and interest in paediatric research. Task-force in Europe for Drug Development for the Young Network of Excellence and Relating Expectations and Needs to the Participation and Empowerment of Children in Clinical Trials project set up an inventory of Ethics Committees existing in Europe and conducted a survey on their approach to paediatric trials. Ethics Committees operating in 22 European Countries participated in this survey. Results showed a high lack of knowledge, understanding and awareness of the current European paediatric regulatory framework and a lack of involvement of Ethics Committees in paediatric research, especially in terms of training and education, demonstrated also by the decreasing number of Ethics Committees answering exhaustively to the whole questionnaire. The majority of participating Ethics Committees expressed interest in future initiatives related to paediatric research. Despite a limited knowledge and understanding of the current paediatric regulatory framework, a significant number of Ethics Committees operating in Europe show interest in initiatives related to paediatric research. Networking may be an essential tool to be used to enhance Ethics Committees role in supporting paediatric research. Any initiative should be undertaken at European level in collaboration with European Union Institutions. © 2011 The Author(s)/Acta Paediatrica © 2011 Foundation Acta Paediatrica.

Science Interests in Preschool Boys and Girls: Relations to Later Self-Concept and Science Achievement

ERIC Educational Resources Information Center

Leibham, Mary Beth; Alexander, Joyce M.; Johnson, Kathy E.

2013-01-01

Although young children display various types of interests, little is known regarding the potential impact of these interests on subsequent learning and development. Of particular importance is the question of whether or not children's early interests are instrumental in their later academic achievement. The current study fills this gap in the…

Civil Rights and Social Change: The Contributions of Interest Groups, Social Movements, and the Courts.

ERIC Educational Resources Information Center

O'Connor, Karen

1990-01-01

Discusses a faculty seminar on the role of interest groups in the judicial process, focusing on U.S. Supreme Court decisions. Explores the dynamics of social change and defines interest groups. Examines the role of interest groups in civil rights litigation and delineates the contours of the current constitutional changes. Includes seminar…

Shrubs tracing sea surface temperature--Calluna vulgaris on the Faroe Islands.

PubMed

Beil, Ilka; Buras, Allan; Hallinger, Martin; Smiljanić, Marko; Wilmking, Martin

2015-11-01

The climate of Central and Northern Europe is highly influenced by the North Atlantic Ocean due to heat transfer from lower latitudes. Detailed knowledge about spatio-temporal variability of sea surface temperature (SST) in that region is thus of high interest for climate and environmental research. Because of the close relations between ocean and coastal climate and the climate sensitivity of plant growth, annual rings of woody plants in coastal regions might be used as a proxy for SST. We show here for the first time the proxy potential of the common and widespread evergreen dwarf shrub Calluna vulgaris (heather), using the Faroe Islands as our case study. Despite its small and irregular ring structure, the species seems suitable for dendroecological investigations. Ring width showed high and significant correlations with summer and winter air temperatures and SST. The C. vulgaris chronology from the Faroe Islands, placed directly within the North Atlantic Current, clearly reflects variations in summer SSTs over an area between Iceland and Scotland. Utilising shrubs like C. vulgaris as easy accessible and annually resolved proxies offers an interesting possibility for reconstruction of the coupled climate-ocean system at high latitudes.

Creation of High Resolution Terrain Models of Barringer Meteorite Crater (Meteor Crater) Using Photogrammetry and Terrestrial Laser Scanning Methods

NASA Technical Reports Server (NTRS)

Brown, Richard B.; Navard, Andrew R.; Holland, Donald E.; McKellip, Rodney D.; Brannon, David P.

2010-01-01

Barringer Meteorite Crater or Meteor Crater, AZ, has been a site of high interest for lunar and Mars analog crater and terrain studies since the early days of the Apollo-Saturn program. It continues to be a site of exceptional interest to lunar, Mars, and other planetary crater and impact analog studies because of its relatively young age (est. 50 thousand years) and well-preserved structure. High resolution (2 meter to 1 decimeter) digital terrain models of Meteor Crater in whole or in part were created at NASA Stennis Space Center to support several lunar surface analog modeling activities using photogrammetric and ground based laser scanning techniques. The dataset created by this activity provides new and highly accurate 3D models of the inside slope of the crater as well as the downslope rock distribution of the western ejecta field. The data are presented to the science community for possible use in furthering studies of Meteor Crater and impact craters in general as well as its current near term lunar exploration use in providing a beneficial test model for lunar surface analog modeling and surface operation studies.

A Futures Orientation in the Australian Curriculum: Current Levels of Teacher Interest, Activity and Support in Western Australia

ERIC Educational Resources Information Center

Paynter, Mark; Bruce, Neville

2014-01-01

The soon to be implemented Australian Curriculum aims to integrate a futures orientation across subject areas. Guidelines and support for this specific initiative are being finalized. Only a little is known about the current teaching of a futures orientation or of secondary teacher interest, understanding and support for this important but…

The Conceptual Landscape of iSchools: Examining Current Research Interests of Faculty Members

ERIC Educational Resources Information Center

Holmberg, Kim

2013-01-01

Introduction: This study describes the intellectual landscape of iSchools and examines how the various iSchools map on to these research areas. Method: The primary focus of the data collection process was on faculty members' current research interests as described by the individuals themselves. A co-word analysis of all iSchool faculty…

Synthesis of a highly efficient 3D graphene-CNT-MnO2-PANI nanocomposite as a binder free electrode material for supercapacitors.

PubMed

Asif, Muhammad; Tan, Yi; Pan, Lujun; Rashad, Muhammad; Li, Jiayan; Fu, Xin; Cui, Ruixue

2016-09-29

Graphene based nanocomposites have been investigated intensively, as electrode materials for energy storage applications. In the current work, a graphene-CNT-MnO 2 -PANI (GCM@PANI) nanocomposite has been synthesized on 3D graphene grown on nickel foam, as a highly efficient binder free electrode material for supercapacitors. Interestingly, the specific capacitance of the synthesized electrode increases up to the first 1500 charge-discharge cycles, and is thus referred to as an electrode activation process. The activated GCM@PANI nanocomposite electrode exhibits an extraordinary galvanostatic specific capacitance of 3037 F g -1 at a current density of 8 A g -1 . The synthesized nanocomposite exhibits an excellent cyclic stability with a capacitance retention of 83% over 12 000 charge-discharge cycles, and a high rate capability by retaining a specific capacitance of 84.6% at a current density of 20 A g -1 . The structural and electrochemical analysis of the synthesized nanocomposite suggests that the astonishing electrochemical performance might be attributed to the growth of a novel PANI nanoparticle layer and the synergistic effect of CNT/MnO 2 nanostructures.

Design of a New Acceleration System for High-Current Pulsed Proton Beams from an ECR Source

NASA Astrophysics Data System (ADS)

Cooper, Andrew L.; Pogrebnyak, Ivan; Surbrook, Jason T.; Kelly, Keegan J.; Carlin, Bret P.; Champagne, Arthur E.; Clegg, Thomas B.

2014-03-01

A primary objective for accelerators at TUNL's Laboratory for Experimental Nuclear Astrophysics (LENA) is to maximize target beam intensity to ensure a high rate of nuclear events during each experiment. Average proton target currents of several mA are needed from LENA's electron cyclotron resonance (ECR) ion source because nuclear cross sections decrease substantially at energies of interest <200 keV. We seek to suppress undesired continuous environmental background by pulsing the beam and detecting events only during beam pulses. To improve beam intensity and transport, we installed a more powerful, stable microwave system for the ECR plasma, and will install a new acceleration system. This system will: reduce defocusing effects of the beam's internal space charge; provide better vacuum with a high gas conductance accelerating column; suppress bremsstrahlung X-rays produced when backstreaming electrons strike internal acceleration tube structures; and provide better heat dissipation by using deionized water to provide the current drain needed to establish the accelerating tube's voltage gradient. Details of beam optical modeling calculations, proposed accelerating tube design, and initial beam pulsing tests will be described. Work supported in part by USDOE Office of HE and Nuclear Physics.

Adults with Pedophilic Interests in the United States: Current Practices and Suggestions for Future Policy and Research.

PubMed

Lasher, Michael P; Stinson, Jill D

2017-04-01

Adults with pedophilic interests are often viewed by the public as a homogenous subgroup based on what we know from those who sexually offend against children. The stigma associated with child sexual abuse may serve to deter such behaviors but may also interfere with the person's stability and willingness to seek assistance in managing pedophilic interests. This article contrasts the sex offender response and prevention efforts typically employed in the U.S. (i.e., containment, registration, and notification policies and public education programs) with treatment programs aimed at preventing child sexual abuse in Germany, Belgium, and Canada. Five major areas are identified that should be further examined with regard to implementing preventative outreach and treatment programs in the U.S.: barriers to outreach and treatment programs, how to expand or reframe current preventative educational programs, implementation of such programs in light of current mandating reporting policies, promising treatment approaches for pedophilic interests among non-offenders, and ethical concerns relevant to preventative psychological interventions.

Feature Tracking for High Speed AFM Imaging of Biopolymers.

PubMed

Hartman, Brett; Andersson, Sean B

2018-03-31

The scanning speed of atomic force microscopes continues to advance with some current commercial microscopes achieving on the order of one frame per second and at least one reaching 10 frames per second. Despite the success of these instruments, even higher frame rates are needed with scan ranges larger than are currently achievable. Moreover, there is a significant installed base of slower instruments that would benefit from algorithmic approaches to increasing their frame rate without requiring significant hardware modifications. In this paper, we present an experimental demonstration of high speed scanning on an existing, non-high speed instrument, through the use of a feedback-based, feature-tracking algorithm that reduces imaging time by focusing on features of interest to reduce the total imaging area. Experiments on both circular and square gratings, as well as silicon steps and DNA strands show a reduction in imaging time by a factor of 3-12 over raster scanning, depending on the parameters chosen.

Solution-Processed Two-Dimensional Metal Dichalcogenide-Based Nanomaterials for Energy Storage and Conversion.

PubMed

Cao, Xiehong; Tan, Chaoliang; Zhang, Xiao; Zhao, Wei; Zhang, Hua

2016-08-01

The development of renewable energy storage and conversion devices is one of the most promising ways to address the current energy crisis, along with the global environmental concern. The exploration of suitable active materials is the key factor for the construction of highly efficient, highly stable, low-cost and environmentally friendly energy storage and conversion devices. The ability to prepare two-dimensional (2D) metal dichalcogenide (MDC) nanosheets and their functional composites in high yield and large scale via various solution-based methods in recent years has inspired great research interests in their utilization for renewable energy storage and conversion applications. Here, we will summarize the recent advances of solution-processed 2D MDCs and their hybrid nanomaterials for energy storage and conversion applications, including rechargeable batteries, supercapacitors, electrocatalytic hydrogen generation and solar cells. Moreover, based on the current progress, we will also give some personal insights on the existing challenges and future research directions in this promising field. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Automated Proton Track Identification in MicroBooNE Using Gradient Boosted Decision Trees

DOE Office of Scientific and Technical Information (OSTI.GOV)

Woodruff, Katherine

MicroBooNE is a liquid argon time projection chamber (LArTPC) neutrino experiment that is currently running in the Booster Neutrino Beam at Fermilab. LArTPC technology allows for high-resolution, three-dimensional representations of neutrino interactions. A wide variety of software tools for automated reconstruction and selection of particle tracks in LArTPCs are actively being developed. Short, isolated proton tracks, the signal for low- momentum-transfer neutral current (NC) elastic events, are easily hidden in a large cosmic background. Detecting these low-energy tracks will allow us to probe interesting regions of the proton's spin structure. An effective method for selecting NC elastic events is tomore » combine a highly efficient track reconstruction algorithm to find all candidate tracks with highly accurate particle identification using a machine learning algorithm. We present our work on particle track classification using gradient tree boosting software (XGBoost) and the performance on simulated neutrino data.« less

Development of a compact bushing for NBI

NASA Astrophysics Data System (ADS)

de Esch, H. P. L.; Simonin, A.; Grand, C.; Lepetit, B.; Lemoine, D.; Márquez-Mijares, M.; Minea, T.; Caillault, L.; Seznec, B.; Jager, T.; Odic, E.; Kirkpatrick, M. J.; Teste, Ph.; Dessante, Ph.; Almaksour, K.

2017-08-01

Research into a novel type of compact bushing is being conducted through the HVIV (High Voltage holding In Vacuum) partnership between CEA-Cadarache1, GeePs-Centralesupélec4, LPGP3 and LCAR2. The bushing aims to concentrate the high electric field inside its interior, rather than in the vacuum tank. Hence the field emission current is also concentrated inside the bushing and it can be attempted to suppress this so-called dark current by conditioning the internal surfaces and by adding gas. LCAR have performed theoretical quantum mechanical studies of electron field emission and the role of adsorbates in changing the work function. LPGP studied the ionization of gas due to field emission current and the behavior of micro particles exposed to emissive electron current in the vacuum gap under high electric fields. Experiments at Geeps have clarified the role of surface conditioning in reducing the dark current. Geeps also found that adding low pressure nitrogen gas to the vacuum is much more effective than helium in reducing the field emission. An interesting observation is the growth of carbon structures after exposure of an electrode to the electric field. Finally, IRFM have performed experiments on a single stage test bushing that features a 36 cm high porcelain insulator and two cylindrical electrode surfaces in vacuum or low-pressure gas. Using 0.1 Pa N2 gas, the voltage holding exceeded 185 kV over a 40 mm "vacuum" gap without dark current. Above this voltage, exterior breakdowns occurred over the insulator, which was in air. The project will finish with the fabrication of a 2-stage compact bushing, capable to withstand 400 kV.

Cold spray NDE for porosity and other process anomalies

NASA Astrophysics Data System (ADS)

Glass, S. W.; Larche, M. R.; Prowant, M. S.; Suter, J. D.; Lareau, J. P.; Jiang, X.; Ross, K. A.

2018-04-01

This paper describes a technology review of nondestructive evaluation (NDE) methods that can be applied to cold spray coatings. Cold spray is a process for depositing metal powder at high velocity so that it bonds to the substrate metal without significant heating that would be likely to cause additional residual tensile stresses. Coatings in the range from millimeters to centimeters are possible at relatively high deposition rates. Cold spray coatings that may be used for hydroelectric components that are subject to erosion, corrosion, wear, and cavitation damage are of interest. The topic of cold spray NDE is treated generally, however, but may be considered applicable to virtually any cold spray application except where there are constraints of the hydroelectric component application that bear special consideration. Optical profilometry, eddy current, ultrasound, and hardness tests are shown for one set of good, fair, and poor nickel-chrome (NiCr) on 304 stainless steel (304SS) cold spray samples to demonstrate inspection possibilities. The primary indicator of cold spray quality is the cold spray porosity that is most directly measured with witness-sample destructive examinations (DE)—mostly photo-micrographs. These DE-generated porosity values are correlated with optical profilometry, eddy current, ultrasound, and hardness test NDE methods to infer the porosity and other information of interest. These parameters of interest primarily include: • Porosity primarily caused by improper process conditions (temperature, gas velocity, spray standoff, spray angle, powder size, condition, surface cleanliness, surface oxide, etc.) • Presence/absence of the cold spray coating including possible over-sprayed voids • Coating thicknessOptical profilometry measurements of surface roughness trended with porosity plus, if compared with a reference measurement or reference drawing, would provide information on the coating thickness. Ultrasound could provide similar surface profile information plus attenuation measurements trended with porosity. The ultrasound measurements, however, may be limited to geometries where the substrate back-wall is normal to the cold spray surface and not too thick. Eddy current showed a strong correlation with porosity. Eddy currents can also be sensitive to cracks and do not need fluid coupling to make measurements, but are not sensitive to coating thicknesses in most cases. Vickers hardness measurements also tracked well with porosity; however, these types of hardness measurements are also not sensitive to coating thickness. An NDE program may include multiple measurements.

Interface Engineering of High-Performance Perovskite Photodetectors Based on PVP/SnO2 Electron Transport Layer.

PubMed

Wang, Ye; Zhang, Xingwang; Jiang, Qi; Liu, Heng; Wang, Denggui; Meng, Junhua; You, Jingbi; Yin, Zhigang

2018-02-21

Hybrid organic-inorganic perovskites have attracted intensive interest as active materials for high-performance photodetectors. However, studies on the electron transport layer (ETL) and its influence on the response time of photodetectors remain limited. Herein, we compare the performances of perovskite photodetectors with TiO 2 and SnO 2 ETLs, especially on the response time. Both photodetectors exhibit a high on/off current ratio of 10 5 , a large detectivity around 10 12 Jones, and a linear dynamic range over 80 dB. The SnO 2 -based perovskite photodiodes show ultrahigh response rates of 3 and 6 μs for the rise and decay times, respectively. However, photodetectors with TiO 2 ETLs have low responsivity and long response time at low driving voltage, which is attributed to the electron extraction barrier at the TiO 2 /perovskite interface and the charge traps in the TiO 2 layer. Furthermore, the dark current of SnO 2 -based perovskite photodiodes is effectively suppressed by inserting a poly(vinylpyrrolidone) interlayer, and then the on/off current ratio increases to 1.2 × 10 6 , corresponding to an improvement of 1 order of magnitude. Such low-cost, solution-processable perovskite photodetectors with high performance show promising potential for future optoelectronic applications.

Electrical and hydrodynamic characterization of a high current pulsed arc

NASA Astrophysics Data System (ADS)

Sousa Martins, R.; Chemartin, L.; Zaepffel, C.; Lalande, Ph; Soufiani, A.

2016-05-01

High current pulsed arcs are of significant industrial interest and, aiming to reduce time and cost, there is progressively more and more need for computation tools that describe and predict the behaviour of these arcs. These simulation codes need inputs and validations by experimental databases, but accurate data is missing for this category of electric discharges. The principal lack of understanding is with respect to the transient phase of the current, which can reach thousands of amperes in a few microseconds. In this paper, we present the work realized on an experimental setup that simulates in the laboratory an arc column subjected to five levels of high pulsed current, ranging from 10 kA to 100 kA, with the last one corresponding to the standard lightning current waveform used in aircraft certification processes. This device was instrumented by high speed video cameras to assess the characteristic sizes of the arc channel and to characterize the shock wave generated by the arc expansion. The arc channel radius was measured over time during the axisymmetric phase and reached 3.2 cm. The position and velocity of the shock wave was determined during the first 140 μs. The background-oriented schlieren method was used to study the shock wave and a model for the light deflection inside the shock wave was developed. The mass density profile of the shock wave was estimated and showed good agreement with Rankine-Hugoniot relations at the wave front. Electrical measurements were also used to estimate the time-dependent resistance and conductivity of the arc for times lasting up to 50 μs.

Students' knowledge of, and attitudes towards biotechnology revisited, 1995-2014: Changes in agriculture biotechnology but not in medical biotechnology.

PubMed

Chen, Shao-Yen; Chu, Yih-Ru; Lin, Chen-Yung; Chiang, Tzen-Yuh

2016-09-10

Modern biotechnology is one of the most important scientific and technological revolutions in the 21st century, with an increasing and measurable impact on society. Development of biotechnology curriculum has become important to high school bioscience classrooms. This study has monitored high school students in Taiwan on their knowledge of and attitudes towards biotechnology for nearly two decades. Not surprisingly, knowledge of biotechnology of current students has increased significantly (p < 0.001) and most students have learned some definitions and examples of biotechnology. There was a positive correlation between biotechnology knowledge and attitudes toward biotechnology for current students who study Advanced Biology (AB). However, for current students who did not study AB, there was a negative correlation.The attitude results showed that students today expressed less favorable opinions toward agricultural biotechnology (p < 0.001) despite studying AB or not. However, there is no significant difference between students today and 18 years ago in opinions towards medical biotechnology. In addition, current students showed a greater concern involving environmental risks than former students. Interestingly, the high school curriculum did affect students' attitudes toward genetically engineered (GE) plants but not GE animals. Our current study also found that the students' attitude towards GE animals was influenced more by their limited knowledge than by their moral belief. On the basis of findings from this study, we suggest that more materials of emerging animal biotechnology should be included in high school curriculum and recommend that high school teachers and university faculty establish a collaborative framework in the near future. © 2016 by The International Union of Biochemistry and Molecular Biology, 44(5):475-491, 2016. © 2016 The International Union of Biochemistry and Molecular Biology.

Initiation of long, free-standing z discharges by CO2 laser gas heating

NASA Astrophysics Data System (ADS)

Niemann, C.; Tauschwitz, A.; Penache, D.; Neff, S.; Knobloch, R.; Birkner, R.; Presura, R.; Hoffmann, D. H. H.; Yu, S. S.; Sharp, W. M.

2002-01-01

High current discharge channels can neutralize both current and space charge of very intense ion beams. Therefore, they are considered an interesting solution for final focus and beam transport in a heavy ion beam fusion reactor. At the Gesellschaft für Schwerionenforschung accelerator facility, 50 cm long, free-standing discharge channels were created in a 60 cm diameter metallic chamber. Discharges with currents of 45 kA in 2 to 25 mbar ammonia (NH3) gas are initiated by a CO2 laser pulse along the channel axis before the capacitor bank is triggered. Resonant absorption of the laser, tuned to the v2 vibration of the ammonia molecule, causes strong gas heating. Subsequent expansion and rarefaction of the gas prepare the conditions for a stable discharge to fulfill the requirements for ion beam transport. The influence of an electric prepulse on the high current discharge was investigated. This article describes the laser-gas interaction and the discharge initiation mechanism. We found that channels are magnetohydrodynamic stable up to currents of 45 kA, measured by fast shutter and streak imaging techniques. The rarefaction of the laser heated gas is studied by means of a one-dimensional Lagrangian fluid code (CYCLOPS) and is identified as the dominant initiation mechanism of the discharge.

High-Fidelity Visual Long-Term Memory within an Unattended Blink of an Eye.

PubMed

Kuhbandner, Christof; Rosas-Corona, Elizabeth A; Spachtholz, Philipp

2017-01-01

What is stored in long-term memory from current sensations is a question that has attracted considerable interest. Over time, several prominent theories have consistently proposed that only attended sensory information leaves a durable memory trace whereas unattended information is not stored beyond the current moment, an assumption that seems to be supported by abundant empirical evidence. Here we show, by using a more sensitive memory test than in previous studies, that this is actually not true. Observers viewed a rapid stream of real-world object pictures overlapped by words (presentation duration per stimulus: 500 ms, interstimulus interval: 200 ms), with the instruction to attend to the words and detect word repetitions, without knowing that their memory would be tested later. In a surprise two-alternative forced-choice recognition test, memory for the unattended object pictures was tested. Memory performance was substantially above chance, even when detailed feature knowledge was necessary for correct recognition, even when tested 24 h later, and even although participants reported that they do not have any memories. These findings suggests that humans have the ability to store at high speed detailed copies of current visual stimulations in long-term memory independently of current intentions and the current attentional focus.

3D indium tin oxide electrodes by ultrasonic spray deposition for current collection applications

NASA Astrophysics Data System (ADS)

van den Ham, E. J.; Elen, K.; Bonneux, G.; Maino, G.; Notten, P. H. L.; Van Bael, M. K.; Hardy, A.

2017-04-01

Three dimensionally (3D) structured indium tin oxide (ITO) thin films are synthesized and characterized as a 3D electrode material for current collection applications. Using metal citrate chemistry in combination with ultrasonic spray deposition, a low cost wet-chemical method has been developed to achieve conformal ITO coatings on non-planar scaffolds. Although there is room for improvement with respect to the resistivity (9.9·10-3 Ω•cm, 220 nm thick planar films), high quality 3D structured coatings were shown to exhibit conductive properties based on ferrocene reactivity. In view of applications in Li-ion batteries, the electrochemical stability of the current collector was investigated, indicating that stability is guaranteed for voltages of 1.5 V and up (vs. Li+/Li). In addition, subsequent 3D coating of the ITO with WO3 as a negative electrode (battery) material confirmed the 3D ITO layer functions as a proper current collector. Using this approach, an over 4-fold capacity increase was booked for 3D structured WO3 in comparison to planar samples, confirming the current collecting capabilities of the 3D ITO coating. Therefore, the 3D ITO presented is considered as a highly interesting material for 3D battery applications and beyond.

[Multiple myeloma: current therapeutic approaches].

PubMed

Troussard, X; Bauduer, F; Leporrier, M

1992-01-01

The therapeutic strategy in multiple myeloma depends on age and tumor mass. Stage I must not be treated. The Melphalan Prednisone regimen is the reference for induction therapy because polychemotherapies are generally not superior. At this phase, the addition of Interferon alpha seems to be interesting. This drug has an important role during the steady-state phase. VAD represents the most efficient chemotherapy. Body hemi-irradiation is also useful. The analgesic effect and the decrease in the tumoral mass are the striking effects of this treatment. In young patients, high dose chemotherapy with bone marrow transplantation is proposed. Verapamil and anti-IL6 antibodies are currently being evaluated. Symptomatic treatment is essential in this non curable disease.

Detrimental effect of interfacial Dzyaloshinskii-Moriya interaction on perpendicular spin-transfer-torque magnetic random access memory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jang, Peong-Hwa; Lee, Seo-Won, E-mail: swlee-sci@korea.ac.kr, E-mail: kj-lee@korea.ac.kr; Song, Kyungmi

2015-11-16

Interfacial Dzyaloshinskii-Moriya interaction in ferromagnet/heavy metal bilayers is recently of considerable interest as it offers an efficient control of domain walls and the stabilization of magnetic skyrmions. However, its effect on the performance of perpendicular spin transfer torque memory has not been explored yet. We show based on numerical studies that the interfacial Dzyaloshinskii-Moriya interaction decreases the thermal energy barrier while increases the switching current. As high thermal energy barrier as well as low switching current is required for the commercialization of spin torque memory, our results suggest that the interfacial Dzyaloshinskii-Moriya interaction should be minimized for spin torque memorymore » applications.« less

Teaching Certificate Program Participants' Perceptions of Mentor-Mentee Relationships.

PubMed

Sheehan, Amy Heck; Gonzalvo, Jasmine D; Ramsey, Darin C; Sprunger, Tracy L

2016-04-25

Objective. To assess teaching certificate program (TCP) participants' perceptions of mentor-mentee relationships. Methods. A 15-item survey instrument was administered to all 2014-2015 participants of the Indiana Pharmacy Teaching Certificate (IPTeC) program. Results. One hundred percent of IPTeC program participants (83/83) responded to the survey. The majority of participants indicated that having a professional mentor was either very important (52%) or important (47%) to their professional development and preferred to choose their own professional mentor (53%). Mentor characteristics rated as highly important by mentees included having similar clinical practice interests (82%), having similar research interests (66%), and being available to meet face-to-face (90%). Age, race, and gender of the mentor were not rated by mentees as important. Conclusion. Teaching certificate program participants place high importance on having a professional mentor. Mentorship of pharmacists completing TCPs should be a priority for current pharmacy faculty members so adequate guidance is available to future pharmacy educators.

Molecular photoionization processes of astrophysical and aeronomical interest

NASA Technical Reports Server (NTRS)

Langhoff, P. W.

1985-01-01

An account is given of aspects of photoionization processes in molecules, with particular reference to recent theoretical and experimental studies of partial cross sections for production of specific final electronic states and of parent and fragment ions. Such cross sections help provide a basis for specifying the state of excitation of the ionized medium, are useful for estimating the kinetic energy distributions of photoejected electrons and fragment ions, provide parent-and fragment-ion yields, and clarify the possible origins of neutral fragments in highly excited rovibronic states. A descriptive account is given of photoionization phenomena, including tabulation of valence- and inner-shell potentials for some molecules of astrophysical and aeronomical interest. Cross sectional expressions are given. Various approximations currently employed in computational studies are described briefly, threshold laws and high-energy limits are indicated, and distinction is drawn between resonant and direct photoionization phenomena. Recent experimental and theoretical studies of partial photoionization cross sections in selected compounds of astrophysical and aeronomical relevance are described and discussed.

Resonant-tunneling oscillators and multipliers for submillimeter receivers

NASA Technical Reports Server (NTRS)

Sollner, T. C. L. Gerhard

1988-01-01

Resonant tunneling through double-barrier heterostructures has attracted increasing interest recently, largely because of the fast charge transport it provides. In addition, the negative differential resistance regions that exist in the current-voltage (I-V) curve (peak-to-valley ratios of 3.5:1 at room temperature, and nearly 10:1 at 77 K, were measured) suggest that high-speed devices based on the character of the I-V curve should be possible. For example, the negative differential resistance region is capable of providing the gain necessary for high-frequency oscillations. In the laboratory attempts were made to increase the frequency and power of these oscillators and to demonstrate several different high-frequency devices.

Relation of Vocational Identity Statuses to Interest Structure among Swiss Adolescents

ERIC Educational Resources Information Center

Hirschi, Andreas

2011-01-01

Vocational identity is one core component of identity construction in adolescence. The current study investigated whether vocational interest structure in terms of differentiation, coherence, elevation, and interest-aspiration congruence would differentiate among students in vocational identity achievement, foreclosure, moratorium, and diffusion.…

From Physics to industry: EOS outside HEP

NASA Astrophysics Data System (ADS)

Espinal, X.; Lamanna, M.

2017-10-01

In the competitive market for large-scale storage solutions the current main disk storage system at CERN EOS has been showing its excellence in the multi-Petabyte high-concurrency regime. It has also shown a disruptive potential in powering the service in providing sync and share capabilities and in supporting innovative analysis environments along the storage of LHC data. EOS has also generated interest as generic storage solution ranging from university systems to very large installations for non-HEP applications.

Current development of podophyllotoxins.

PubMed

Canetta, R; Hilgard, P; Florentine, S; Bedogni, P; Lenaz, L

1982-01-01

The unique biological properties and therapeutic efficacy of the podophyllotoxin derivatives, Vumon (VM26, teniposide) and Vepesid (VP16-213, etoposide), are stimulating the interest of both laboratory and clinical researchers. Investigations on new pharmaceutical formulations, pharmacokinetics and metabolism are providing more appropriate information in drug administration; experimental chemotherapy indicates that, among others, cytosine arabinoside and cisplatin are highly synergistic with podophyllotoxins; single agent and combination treatment clinical trials are defining the respective role of Vumon and Vepesid in cancer chemotherapy.

ELECTROSTATIC ACCELERATORS (in French)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gerbier, R.

1962-04-01

The various methods presently in use for producing the continuous high voltage necessary for the operation of electrostatic accelerators are reviewed. The methods considered are voltage multiplier units (Greinacher and Morganstern types) and electrostatic instruments (Van de Graaff and Trump machines and Felici rotnting cylinder instruments). The electrostatic accelerators used at Grenoble which give currents of several milliamperes at voltages up to 1.2 Mv are described. In this energy region electron accelerators and neutron generators offer very interesting possibilities. (auth)

Current German Laser and Quantum Optics Research Reviewed at the 50th Annual Meeting of the Physikalische Gesellschaft.

DTIC Science & Technology

1986-04-23

Physics, Munster In the area of generating useable University) studied an interesting de- coherent high-frequency radiation, I vice, a silicon Fabry ...has a substantial crys- tingen) described studies with Cr- plus tal growing capability. One paper from Nd-doped gadolinium -scandium-gallium the Hamburg...institute, read by J. Drube, garnets (GSGG), and also with Cr-doped reported on Xe-flashlamp-pumped Cr:CSA(; % gadolinium -scandium-aluminum garnets

Direct observation of turbulent magnetic fields in hot, dense laser produced plasmas

PubMed Central

Mondal, Sudipta; Narayanan, V.; Ding, Wen Jun; Lad, Amit D.; Hao, Biao; Ahmad, Saima; Wang, Wei Min; Sheng, Zheng Ming; Sengupta, Sudip; Kaw, Predhiman; Das, Amita; Kumar, G. Ravindra

2012-01-01

Turbulence in fluids is a ubiquitous, fascinating, and complex natural phenomenon that is not yet fully understood. Unraveling turbulence in high density, high temperature plasmas is an even bigger challenge because of the importance of electromagnetic forces and the typically violent environments. Fascinating and novel behavior of hot dense matter has so far been only indirectly inferred because of the enormous difficulties of making observations on such matter. Here, we present direct evidence of turbulence in giant magnetic fields created in an overdense, hot plasma by relativistic intensity (1018W/cm2) femtosecond laser pulses. We have obtained magneto-optic polarigrams at femtosecond time intervals, simultaneously with micrometer spatial resolution. The spatial profiles of the magnetic field show randomness and their k spectra exhibit a power law along with certain well defined peaks at scales shorter than skin depth. Detailed two-dimensional particle-in-cell simulations delineate the underlying interaction between forward currents of relativistic energy “hot” electrons created by the laser pulse and “cold” return currents of thermal electrons induced in the target. Our results are not only fundamentally interesting but should also arouse interest on the role of magnetic turbulence induced resistivity in the context of fast ignition of laser fusion, and the possibility of experimentally simulating such structures with respect to the sun and other stellar environments. PMID:22566660

Direct observation of turbulent magnetic fields in hot, dense laser produced plasmas.

PubMed

Mondal, Sudipta; Narayanan, V; Ding, Wen Jun; Lad, Amit D; Hao, Biao; Ahmad, Saima; Wang, Wei Min; Sheng, Zheng Ming; Sengupta, Sudip; Kaw, Predhiman; Das, Amita; Kumar, G Ravindra

2012-05-22

Turbulence in fluids is a ubiquitous, fascinating, and complex natural phenomenon that is not yet fully understood. Unraveling turbulence in high density, high temperature plasmas is an even bigger challenge because of the importance of electromagnetic forces and the typically violent environments. Fascinating and novel behavior of hot dense matter has so far been only indirectly inferred because of the enormous difficulties of making observations on such matter. Here, we present direct evidence of turbulence in giant magnetic fields created in an overdense, hot plasma by relativistic intensity (10(18) W/cm(2)) femtosecond laser pulses. We have obtained magneto-optic polarigrams at femtosecond time intervals, simultaneously with micrometer spatial resolution. The spatial profiles of the magnetic field show randomness and their k spectra exhibit a power law along with certain well defined peaks at scales shorter than skin depth. Detailed two-dimensional particle-in-cell simulations delineate the underlying interaction between forward currents of relativistic energy "hot" electrons created by the laser pulse and "cold" return currents of thermal electrons induced in the target. Our results are not only fundamentally interesting but should also arouse interest on the role of magnetic turbulence induced resistivity in the context of fast ignition of laser fusion, and the possibility of experimentally simulating such structures with respect to the sun and other stellar environments.

Leveraging Engineering of Indocyanine Green-Encapsulated Polymeric Nanocomposites for Biomedical Applications.

PubMed

Han, Ya-Hui; Kankala, Ranjith Kumar; Wang, Shi-Bin; Chen, Ai-Zheng

2018-05-24

In recent times, photo-induced therapeutics have attracted enormous interest from researchers due to such attractive properties as preferential localization, excellent tissue penetration, high therapeutic efficacy, and minimal invasiveness, among others. Numerous photosensitizers have been considered in combination with light to realize significant progress in therapeutics. Along this line, indocyanine green (ICG), a Food and Drug Administration (FDA)-approved near-infrared (NIR, >750 nm) fluorescent dye, has been utilized in various biomedical applications such as drug delivery, imaging, and diagnosis, due to its attractive physicochemical properties, high sensitivity, and better imaging view field. However, ICG still suffers from certain limitations for its utilization as a molecular imaging probe in vivo, such as concentration-dependent aggregation, poor in vitro aqueous stability and photodegradation due to various physicochemical attributes. To overcome these limitations, much research has been dedicated to engineering numerous multifunctional polymeric composites for potential biomedical applications. In this review, we aim to discuss ICG-encapsulated polymeric nanoconstructs, which are of particular interest in various biomedical applications. First, we emphasize some attractive properties of ICG (including physicochemical characteristics, optical properties, metabolic features, and other aspects) and some of its current limitations. Next, we aim to provide a comprehensive overview highlighting recent reports on various polymeric nanoparticles that carry ICG for light-induced therapeutics with a set of examples. Finally, we summarize with perspectives highlighting the significant outcome, and current challenges of these nanocomposites.

Spin-torque resonant expulsion of the vortex core for an efficient radiofrequency detection scheme.

PubMed

Jenkins, A S; Lebrun, R; Grimaldi, E; Tsunegi, S; Bortolotti, P; Kubota, H; Yakushiji, K; Fukushima, A; de Loubens, G; Klein, O; Yuasa, S; Cros, V

2016-04-01

It has been proposed that high-frequency detectors based on the so-called spin-torque diode effect in spin transfer oscillators could eventually replace conventional Schottky diodes due to their nanoscale size, frequency tunability and large output sensitivity. Although a promising candidate for information and communications technology applications, the output voltage generated from this effect has still to be improved and, more pertinently, reduces drastically with decreasing radiofrequency (RF) current. Here we present a scheme for a new type of spintronics-based high-frequency detector based on the expulsion of the vortex core in a magnetic tunnel junction (MTJ). The resonant expulsion of the core leads to a large and sharp change in resistance associated with the difference in magnetoresistance between the vortex ground state and the final C-state configuration. Interestingly, this reversible effect is independent of the incoming RF current amplitude, offering a fast real-time RF threshold detector.

Measurement of solar extinction in tower plants with digital cameras

NASA Astrophysics Data System (ADS)

Ballestrín, J.; Monterreal, R.; Carra, M. E.; Fernandez-Reche, J.; Barbero, J.; Marzo, A.

2016-05-01

Atmospheric extinction of solar radiation between the heliostat field and the receiver is accepted as a non-negligible source of energy loss in the increasingly large central receiver plants. However, the reality is that there is currently no reliable measurement method for this quantity and at present these plants are designed, built and operated without knowing this local parameter. Nowadays digital cameras are used in many scientific applications for their ability to convert available light into digital images. Its broad spectral range, high resolution and high signal to noise ratio, make them an interesting device in solar technology. In this work a method for atmospheric extinction measurement based on digital images is presented. The possibility of defining a measurement setup in circumstances similar to those of a tower plant increases the credibility of the method. This procedure is currently being implemented at Plataforma Solar de Almería.

The Astrophysical Multimessenger Observatory Network (AMON)

NASA Technical Reports Server (NTRS)

Smith. M. W. E.; Fox, D. B.; Cowen, D. F.; Meszaros, P.; Tesic, G.; Fixelle, J.; Bartos, I.; Sommers, P.; Ashtekar, Abhay; Babu, G. Jogesh;

Immunoregulation by Mesenchymal Stem Cells: Biological Aspects and Clinical Applications

PubMed Central

Castro-Manrreza, Marta E.; Montesinos, Juan J.

2015-01-01

Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiation into mesenchymal lineages and that can be isolated from various tissues and easily cultivated in vitro. Currently, MSCs are of considerable interest because of the biological characteristics that confer high potential applicability in the clinical treatment of many diseases. Specifically, because of their high immunoregulatory capacity, MSCs are used as tools in cellular therapies for clinical protocols involving immune system alterations. In this review, we discuss the current knowledge about the capacity of MSCs for the immunoregulation of immunocompetent cells and emphasize the effects of MSCs on T cells, principal effectors of the immune response, and the immunosuppressive effects mediated by the secretion of soluble factors and membrane molecules. We also describe the mechanisms of MSC immunoregulatory modulation and the participation of MSCs as immune response regulators in several autoimmune diseases, and we emphasize the clinical application in graft versus host disease (GVHD). PMID:25961059

Advances in utilization of renewable substrates for biosurfactant production

PubMed Central

2011-01-01

Biosurfactants are amphiphilic molecules that have both hydrophilic and hydrophobic moieties which partition preferentially at the interfaces such as liquid/liquid, gas/liquid or solid/liquid interfaces. Such characteristics enable emulsifying, foaming, detergency and dispersing properties. Their low toxicity and environmental friendly nature and the wide range of potential industrial applications in bioremediation, health care, oil and food processing industries makes them a highly sought after group of chemical compounds. Interest in them has also been encouraged because of the potential advantages they offer over their synthetic counterparts in many fields spanning environmental, food, biomedical, petrochemical and other industrial applications. Their large scale production and application however are currently restricted by the high cost of production and by the limited understanding of their interactions with cells and with the abiotic environment. In this paper, we review the current knowledge and latest advances in the search for cost effective renewable agro industrial alternative substrates for their production. PMID:21906330

Optical Remote Sensing of Electric Fields Above Thunderstorms

NASA Astrophysics Data System (ADS)

Burns, B. M.; Carlson, B. E.; Lauben, D.; Cohen, M.; Smith, D.; Inan, U. S.

2010-12-01

Measurement of thunderstorm electric fields typically require balloon-borne measurements in the region of interest. Such measurements are cumbersome and provide limited information at a single point. Remote sensing of electric fields by Kerr-effect induced optical polarization changes of background skylight circumvents many of these difficulties and can in principle provide a high-speed movie of electric field behavior. Above-thundercloud 100 kV/m quasi-static electric fields are predicted to produce polarization changes at above the part in one million level that should be detectable at a ground instrument featuring 1 cm2sr geometric factor and 1 kHz bandwidth (though more sensitivity is nonetheless desired). Currently available optical and electronic components may meet these requirements. We review the principles of this measurement and discuss the current status of a field-ready prototype instrument currently in construction.

The MAJORANA DEMONSTRATOR for 0νββ: Current Status and Future Plans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green, M. P.; Abgrall, N.; Aguayo, Estanislao

2015-03-24

The Majorana Demonstrator will search for neutrinoless-double-beta decay in 76Ge, while establishing the feasibility of a future tonne-scale germanium-based neutrinoless-double-beta decay experiment, and performing searches for new physics beyond the Standard Model. The experiment, currently under construction at the Sanford Underground Research Facility in Lead, SD, will consist of a pair of modular high-purity germanium detector arrays housed inside of a compact copper, lead, and polyethylene shield. Through a combination of strict materials qualifications and assay, low-background design, and powerful background rejection techniques, the Demonstrator aims to achieve a background rate in the neutrinoless-double-beta decay region of interest (ROI) ofmore » no more than 3cnts/(ROI-t-y). The current status of the Demonstrator is discussed, as are plans for its completion.« less

Conduction mechanism change with transport oxide layer thickness in oxide hetero-interface diode

NASA Astrophysics Data System (ADS)

Nam, Bu-il; Park, Jong Seo; Lim, Keon-Hee; Ahn, Yong-keon; Lee, Jinwon; Park, Jun-woo; Cho, Nam-Kwang; Lee, Donggun; Lee, Han-Bo-Ram; Kim, Youn Sang

2017-07-01

An effective and facile strategy is proposed to demonstrate an engineered oxide hetero-interface of a thin film diode with a high current density and low operating voltage. The electrical characteristics of an oxide hetero-interface thin film diode are governed by two theoretical models: the space charge-limited current model and the Fowler-Nordheim (F-N) tunneling model. Interestingly, the dominant mechanism strongly depends on the insulator thickness, and the mechanism change occurs at a critical thickness. This paper shows that conduction mechanisms of oxide hetero-interface thin film diodes depend on thicknesses of transport oxide layers and that current densities of these can be exponentially increased through quantum tunneling in the diodes with the thicknesses less than 10 nm. These oxide hetero-interface diodes have great potential for low-powered transparent nanoscale applications.

Construction of Nitrogen-Doped Carbon-Coated MoSe2 Microspheres with Enhanced Performance for Lithium Storage.

PubMed

Tang, Wangjia; Xie, Dong; Shen, Tong; Wang, Xiuli; Wang, Donghuang; Zhang, Xuqing; Xia, Xinhui; Wu, Jianbo; Tu, Jiangping

2017-09-18

Exploring advanced anode materials with highly reversible capacity have gained great interests for large-scale lithium storage. A facile two-step method is developed to synthesize nitrogen-doped carbon coated MoSe 2 microspheres via hydrothermal plus thermal polymerization. The MoSe 2 microspheres composed of interconnected nanoflakes are homogeneously coated by a thin nitrogen-doped carbon (N-C) layer. As an anode for lithium ion batteries, the MoSe 2 /N-C composite shows better reversibility, smaller polarization, and higher electrochemical reactivity as compared to the unmodified MoSe 2 microspheres. The MoSe 2 /N-C electrode delivers a high specific capacity of 698 mAh g -1 after 100 cycles at a current density of 100 mA g -1 and good high rate performance (471 mAh g -1 at a high current density of 2000 mA g -1 ). The improved electrochemical performance is attributed to the conductive N-C coating and hierarchical microsphere structure with fast ion/electron transfer characteristics. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Three-Dimensional Honeycomb-Like Porous Carbon with Both Interconnected Hierarchical Porosity and Nitrogen Self-Doping from Cotton Seed Husk for Supercapacitor Electrode.

PubMed

Chen, Hui; Wang, Gang; Chen, Long; Dai, Bin; Yu, Feng

2018-06-08

Hierarchical porous structures with surface nitrogen-doped porous carbon are current research topics of interest for high performance supercapacitor electrode materials. Herein, a three-dimensional (3D) honeycomb-like porous carbon with interconnected hierarchical porosity and nitrogen self-doping was synthesized by simple and cost-efficient one-step KOH activation from waste cottonseed husk (a-CSHs). The obtained a-CSHs possessed hierarchical micro-, meso-, and macro-pores, a high specific surface area of 1694.1 m²/g, 3D architecture, and abundant self N-doping. Owing to these distinct features, a-CSHs delivered high specific capacitances of 238 F/g and 200 F/g at current densities of 0.5 A/g and 20 A/g, respectively, in a 6 mol/L KOH electrolyte, demonstrating good capacitance retention of 84%. The assembled a-CSHs-based symmetric supercapacitor also displayed high specific capacitance of 52 F/g at 0.5 A/g, with an energy density of 10.4 Wh/Kg at 300 W/Kg, and 91% capacitance retention after 5000 cycles at 10 A/g.

High strain rate characterization of soft materials: past, present and possible futures

NASA Astrophysics Data System (ADS)

Siviour, Clive

2015-06-01

The high strain rate properties of low impedance materials have long been of interest to the community: the very first paper by Kolsky on his eponymous bars included data from man-made polymers and natural rubber. However, it has also long been recognized that characterizing soft or low impedance specimens under dynamic loading presents a number of challenges, mainly owing to the low sound speed in, and low stresses supported by, these materials. Over the past 20 years, significant progress has been made in high rate testing techniques, including better experimental design, more sensitive data acquisition and better understanding of specimen behavior. Further, a new generation of techniques, in which materials are characterized using travelling waves, rather than in a state of static equilibrium, promise to turn those properties that were previously a drawback into an advantage. This paper will give an overview of the history of high rate characterization, the current state of the art after an exciting couple of decades and some of the techniques currently being developed that have the potential to offer increased quality data in the future.

First high speed imaging of lightning from summer thunderstorms over India: Preliminary results based on amateur recording using a digital camera

NASA Astrophysics Data System (ADS)

Narayanan, V. L.

2017-12-01

For the first time, high speed imaging of lightning from few isolated tropical thunderstorms are observed from India. The recordings are made from Tirupati (13.6oN, 79.4oE, 180 m above mean sea level) during summer months with a digital camera capable of recording high speed videos up to 480 fps. At 480 fps, each individual video file is recorded for 30 s resulting in 14400 deinterlaced images per video file. An automatic processing algorithm is developed for quick identification and analysis of the lightning events which will be discussed in detail. Preliminary results indicating different types of phenomena associated with lightning like stepped leader, dart leader, luminous channels corresponding to continuing current and M components are discussed. While most of the examples show cloud to ground discharges, few interesting cases of intra-cloud, inter-cloud and cloud-air discharges will also be displayed. This indicates that though high speed cameras with few 1000 fps are preferred for a detailed study on lightning, moderate range CMOS sensor based digital cameras can provide important information as well. The lightning imaging activity presented herein is initiated as an amateur effort and currently plans are underway to propose a suite of supporting instruments to conduct coordinated campaigns. The images discussed here are acquired from normal residential area and indicate how frequent lightning strikes are in such tropical locations during thunderstorms, though no towering structures are nearby. It is expected that popularizing of such recordings made with affordable digital cameras will trigger more interest in lightning research and provide a possible data source from amateur observers paving the way for citizen science.

42 CFR 23.25 - How will interest rates for loans be determined?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 42 Public Health 1 2010-10-01 2010-10-01 false How will interest rates for loans be determined? 23... will interest rates for loans be determined? Interest will be charged at the Treasury Current Value of Funds (CVF) rate in effect on April 1 immediately preceding the date on which the loan is approved and...

19 CFR 24.3a - CBP bills; interest assessment; delinquency; notice to principal and surety.

Code of Federal Regulations, 2011 CFR

2011-04-01

... of 1954 (26 U.S.C. 6621, 6622). The current rate of interest will appear on the CBP bill and may be... 19 Customs Duties 1 2011-04-01 2011-04-01 false CBP bills; interest assessment; delinquency....3a CBP bills; interest assessment; delinquency; notice to principal and surety. (a) Due date of CBP...

Non-Hydrostatic Modelling of Waves and Currents over Subtle Bathymetric Features

NASA Astrophysics Data System (ADS)

Gomes, E.; Mulligan, R. P.; McNinch, J.

2014-12-01

Localized areas with high rates of shoreline erosion on beaches, referred to as erosional hotspots, can occur near clusters of relict shore-oblique sandbars. Wave transformation and wave-driven currents over these morphological features could provide an understanding of the hydrodynamic-morphologic coupling mechanism that connects them to the occurrence of erosional hotspots. To investigate this, we use the non-hydrostatic SWASH model that phase-resolves the free surface and fluid motions throughout the water column, allowing for high resolution of wave propagation and breaking processes. In this study we apply a coupled system of nested models including SWAN over a large domain of the North Carolina shelf with smaller nested SWASH domains in areas of interest to determine the hydrodynamic processes occurring over shore oblique bars. In this presentation we focus on a high resolution grid (10 vertical layers, 10 m horizontal resolution) applied to the Duck region with model validation from acoustic wave and current data, and observations from the Coastal Lidar And Radar Imaging System (CLARIS). By altering the bathymetry input for each model run based on bathymetric surveys and comparing the predicted and observed wave heights and current profiles, the effects of subtle bathymetric perturbations have on wave refraction, wave breaking, surf zone currents and vorticity are investigated. The ability to predict wave breaking and hydrodynamics with a non-hydrostatic model may improve our understanding of surf zone dynamics in relation to morphologic conditions.

Partial spin absorption induced magnetization switching and its voltage-assisted improvement in an asymmetrical all spin logic device at the mesoscopic scale

NASA Astrophysics Data System (ADS)

Zhang, Yue; Zhang, Zhizhong; Wang, Lezhi; Nan, Jiang; Zheng, Zhenyi; Li, Xiang; Wong, Kin; Wang, Yu; Klein, Jacques-Olivier; Khalili Amiri, Pedram; Zhang, Youguang; Wang, Kang L.; Zhao, Weisheng

2017-07-01

Beyond memory and storage, future logic applications put forward higher requirements for electronic devices. All spin logic devices (ASLDs) have drawn exceptional interest as they utilize pure spin current instead of charge current, which could promise ultra-low power consumption. However, relatively low efficiencies of spin injection, transport, and detection actually impede high-speed magnetization switching and challenge perspectives of ASLD. In this work, we study partial spin absorption induced magnetization switching in asymmetrical ASLD at the mesoscopic scale, in which the injector and detector have the nano-fabrication compatible device size (>100 nm) and their contact areas are different. The enlarged contact area of the detector is conducive to the spin current absorption, and the contact resistance difference between the injector and the detector can decrease the spin current backflow. Rigorous spin circuit modeling and micromagnetic simulations have been carried out to analyze the electrical and magnetic features. The results show that, at the fabrication-oriented technology scale, the ferromagnetic layer can hardly be switched by geometrically partial spin current absorption. The voltage-controlled magnetic anisotropy (VCMA) effect has been applied on the detector to accelerate the magnetization switching by modulating magnetic anisotropy of the ferromagnetic layer. With a relatively high VCMA coefficient measured experimentally, a voltage of 1.68 V can assist the whole magnetization switching within 2.8 ns. This analysis and improving approach will be of significance for future low-power, high-speed logic applications.

Quality Circles in the Navy: Productivity Improvement or Just Another Program?

DTIC Science & Technology

1981-07-01

related problems and recommend solutions to management. Interest in implementation of QCs is spreading rapidly in both the public and private sectors . Ci...main objectives are to (I) describe QCs, (2) provide information regarding current interest and involvement in QCs in Navy and private sector ...3 QCs in the Private Sector . .. ......... ......... ... 4 Current Use of QCs in the Navy .. .. ...... ............. 4 Impact of QCs

Does Hot Water Freeze Faster Than Cold? Or Why Mpemba's Ice Cream Is a Discrepant Event

ERIC Educational Resources Information Center

Palmer, Bill

1993-01-01

A discrepant event is a happening contrary to our current beliefs. Discrepant events are said to be useful in clarifying concepts. This is one of the interesting features of current theories of constructivism. The story of Mpemba's ice cream is quite well known, but it is the educational aspects of the experiment that are of interest in this…

Recent advances in female sexual dysfunction.

PubMed

Davis, A R

2000-06-01

Female sexuality has received little scientific study. Recently, increased interest in this field has generated new research in the epidemiology, pathophysiology, and pharmacotherapy of female sexual dysfunction (FSD). A new FSD classification system has been proposed. Although sexual difficulties are highly prevalent among women, the degree of associated distress is unknown. Risk factors for FSD are probably both psychologic and physiologic. Aging or menopause is associated with lubrication difficulties, which can be treated with hormone replacement. Hysterectomy seems more likely to result in improvement rather then deterioration of sexual functioning. Depression may be a predictor of sexual dysfunction after hysterectomy. Vasoactive agents are currently being evaluated as treatment for female sexual arousal disorder. The most important advance in the study of female sexual function is the recent surge of interest in this relatively unexplored field.

Luminescence and scintillation properties of XPO 4:Nd 3+ (X = Y, Lu, Sc, La) crystals

DOE PAGES

Makowski, Michal; Witkowski, Marcin E.; Drozdowski, Winicjusz; ...

2018-04-12

Due to their very fast short-wavelength emission, neodymium-doped materials are a subject of current interest as potential scintillators. Although the initial reports regarding neodymium-doped orthophosphates (in crystalline form) and their scintillation properties appeared almost twenty years ago, they remain an interesting class of materials since there is no in-depth understanding of their fundamental scintillation mechanism. In the present research, we focus on the crystalline systems: XPO 4:Nd 3+, where X = Y, Lu, La, Sc. The pulse height, optical absorption, radioluminescence and photoluminescence spectra were investigated and are reported here for various temperatures from 10 to 350 K. Here, resultsmore » of both low and high temperature thermoluminescence measurements are reported in this communication.« less

Broadcast media and the dissemination of weather information

NASA Technical Reports Server (NTRS)

Byrnes, J.

1973-01-01

Although television is the public's most preferred source of weather information, it fails to provide weather reports to those groups who seek the information early in the day and during the day. The result is that many people most often use radio as a source of information, yet preferring the medium of television. The public actively seeks weather information from both radio and TV stations, usually seeking information on current conditions and short range forecasts. forecasts. Nearly all broadcast stations surveyed were eager to air severe weather bulletins quickly and often. Interest in Nowcasting was high among radio and TV broadcasters, with a significant portion indicating a willingness to pay something for the service. However, interest among TV stations in increasing the number of daily reports was small.

Eric Davidson and deep time.

PubMed

Erwin, Douglas H

2017-10-13

Eric Davidson had a deep and abiding interest in the role developmental mechanisms played in generating evolutionary patterns documented in deep time, from the origin of the euechinoids to the processes responsible for the morphological architectures of major animal clades. Although not an evolutionary biologist, Davidson's interests long preceded the current excitement over comparative evolutionary developmental biology. Here I discuss three aspects at the intersection between his research and evolutionary patterns in deep time: First, understanding the mechanisms of body plan formation, particularly those associated with the early diversification of major metazoan clades. Second, a critique of early claims about ancestral metazoans based on the discoveries of highly conserved genes across bilaterian animals. Third, Davidson's own involvement in paleontology through a collaborative study of the fossil embryos from the Ediacaran Doushantuo Formation in south China.

Luminescence and scintillation properties of XPO 4:Nd 3+ (X = Y, Lu, Sc, La) crystals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Makowski, Michal; Witkowski, Marcin E.; Drozdowski, Winicjusz

Due to their very fast short-wavelength emission, neodymium-doped materials are a subject of current interest as potential scintillators. Although the initial reports regarding neodymium-doped orthophosphates (in crystalline form) and their scintillation properties appeared almost twenty years ago, they remain an interesting class of materials since there is no in-depth understanding of their fundamental scintillation mechanism. In the present research, we focus on the crystalline systems: XPO 4:Nd 3+, where X = Y, Lu, La, Sc. The pulse height, optical absorption, radioluminescence and photoluminescence spectra were investigated and are reported here for various temperatures from 10 to 350 K. Here, resultsmore » of both low and high temperature thermoluminescence measurements are reported in this communication.« less

Marine Polysaccharides in Pharmaceutical Applications: An Overview

PubMed Central

Laurienzo, Paola

2010-01-01

The enormous variety of polysaccharides that can be extracted from marine plants and animal organisms or produced by marine bacteria means that the field of marine polysaccharides is constantly evolving. Recent advances in biological techniques allow high levels of polysaccharides of interest to be produced in vitro. Biotechnology is a powerful tool to obtain polysaccharides from a variety of micro-organisms, by controlling the growth conditions in a bioreactor while tailoring the production of biologically active compounds. Following an overview of the current knowledge on marine polysaccharides, with special attention to potential pharmaceutical applications and to more recent progress on the discovering of new polysaccharides with biological appealing characteristics, this review will focus on possible strategies for chemical or physical modification aimed to tailor the final properties of interest. PMID:20948899

[Establishing and operating a human biobank. Ethical aspects].

PubMed

Jahns, Roland

2016-03-01

Particularly in the past decade which has been marked by efforts to foster individualized/personalized medicine the need for well-characterized high-quality collections of human biological material has significantly increased. When establishing and operating a human biobank the interests and the "freedom" of biomedical research must always be weighed against the interests and rights of patients and/or donors; in this process ethical aspects should be considered systematically. In addition, the importance of quality control and quality assurance has largely increased in human biobanking, both from a scientific and even more from an ethical point of view, because donated biological materials are potentially stored for decades and (on request) might serve for currently not foreseeable biomedical research purposes. In addition, the compatibility of national human biobanks with international biobank networks becomes increasingly important.

Web 2.0 technologies for undergraduate and postgraduate medical education: an online survey

PubMed Central

Sandars, J; Schroter, S

2007-01-01

Objectives To identify the current familiarity and use of Web 2.0 technologies by medical students and qualified medical practitioners, and to identify the barriers to its use for medical education. Methods A semi‐structured online questionnaire survey of 3000 medical students and 3000 qualified medical practitioners (consultants, general practitioners and doctors in training) on the British Medical Association's membership database. Results All groups had high familiarity, but low use, of podcasts. Ownership of digital media players was higher among medical students. There was high familiarity, but low use, of other Web 2.0 technologies except for high use of instant messaging and social networking by medical students. All groups stated that they were interested in using Web 2.0 technologies for education but there was lack of knowledge and skills in how to use these new technologies. Conclusions There is an overall high awareness of a range of new Web 2.0 technologies by both medical students and qualified medical practitioners and high interest in its use for medical education. However, the potential of Web 2.0 technologies for undergraduate and postgraduate medical education will only be achieved if there is increased training in how to use this new approach. PMID:18057175

High-Dimensional Intrinsic Interpolation Using Gaussian Process Regression and Diffusion Maps

DOE PAGES

Thimmisetty, Charanraj A.; Ghanem, Roger G.; White, Joshua A.; ...

2017-10-10

This article considers the challenging task of estimating geologic properties of interest using a suite of proxy measurements. The current work recast this task as a manifold learning problem. In this process, this article introduces a novel regression procedure for intrinsic variables constrained onto a manifold embedded in an ambient space. The procedure is meant to sharpen high-dimensional interpolation by inferring non-linear correlations from the data being interpolated. The proposed approach augments manifold learning procedures with a Gaussian process regression. It first identifies, using diffusion maps, a low-dimensional manifold embedded in an ambient high-dimensional space associated with the data. Itmore » relies on the diffusion distance associated with this construction to define a distance function with which the data model is equipped. This distance metric function is then used to compute the correlation structure of a Gaussian process that describes the statistical dependence of quantities of interest in the high-dimensional ambient space. The proposed method is applicable to arbitrarily high-dimensional data sets. Here, it is applied to subsurface characterization using a suite of well log measurements. The predictions obtained in original, principal component, and diffusion space are compared using both qualitative and quantitative metrics. Considerable improvement in the prediction of the geological structural properties is observed with the proposed method.« less

High-Dimensional Intrinsic Interpolation Using Gaussian Process Regression and Diffusion Maps

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thimmisetty, Charanraj A.; Ghanem, Roger G.; White, Joshua A.

This article considers the challenging task of estimating geologic properties of interest using a suite of proxy measurements. The current work recast this task as a manifold learning problem. In this process, this article introduces a novel regression procedure for intrinsic variables constrained onto a manifold embedded in an ambient space. The procedure is meant to sharpen high-dimensional interpolation by inferring non-linear correlations from the data being interpolated. The proposed approach augments manifold learning procedures with a Gaussian process regression. It first identifies, using diffusion maps, a low-dimensional manifold embedded in an ambient high-dimensional space associated with the data. Itmore » relies on the diffusion distance associated with this construction to define a distance function with which the data model is equipped. This distance metric function is then used to compute the correlation structure of a Gaussian process that describes the statistical dependence of quantities of interest in the high-dimensional ambient space. The proposed method is applicable to arbitrarily high-dimensional data sets. Here, it is applied to subsurface characterization using a suite of well log measurements. The predictions obtained in original, principal component, and diffusion space are compared using both qualitative and quantitative metrics. Considerable improvement in the prediction of the geological structural properties is observed with the proposed method.« less

7 CFR 770.10 - Servicing.

Code of Federal Regulations, 2014 CFR

2014-01-01

... enrolled tribal members which is less than 50 percent of the Federally established poverty income rate...) Interest rate reduction. The Agency may consider a reduction of the interest rate for an existing loan to the current interest rate as available from any Agency office provided: (1) The borrower submits a...

7 CFR 770.10 - Servicing.

Code of Federal Regulations, 2013 CFR

2013-01-01

... enrolled tribal members which is less than 50 percent of the Federally established poverty income rate...) Interest rate reduction. The Agency may consider a reduction of the interest rate for an existing loan to the current interest rate as available from any Agency office provided: (1) The borrower submits a...

7 CFR 770.10 - Servicing.

Code of Federal Regulations, 2012 CFR

2012-01-01

... enrolled tribal members which is less than 50 percent of the Federally established poverty income rate...) Interest rate reduction. The Agency may consider a reduction of the interest rate for an existing loan to the current interest rate as available from any Agency office provided: (1) The borrower submits a...

7 CFR 770.10 - Servicing.

Code of Federal Regulations, 2011 CFR

2011-01-01

... enrolled tribal members which is less than 50 percent of the Federally established poverty income rate...) Interest rate reduction. The Agency may consider a reduction of the interest rate for an existing loan to the current interest rate as available from any Agency office provided: (1) The borrower submits a...

7 CFR 1951.223 - Reamortization.

Code of Federal Regulations, 2010 CFR

2010-01-01

... delinquent amount. Accrued interest will be at the rate currently reflected in Finance Office records. (1... government's interest will remain adequately protected if the security position will be affected. (3) Notes...; and (E) The interest rate. (iii) A payment will be due on the next scheduled due date. Deferment of...

Occupational Interests and Mentally Retarded People: Review and Recommendations.

ERIC Educational Resources Information Center

Stodden, Robert A.; And Others

1979-01-01

The article reviews several studies regarding the choice of occupational interests for the mentally retarded adolescent. Several concerns about current evaluation practices are discussed. Recommendations are offered for a client centered, developmental model, making the evaluation of occupational interests a viable part of the client's…

Atomic Data Needs for X-Ray Astronomy

NASA Technical Reports Server (NTRS)

Kallman, Timothy; White, Nicholas E. (Technical Monitor)

1999-01-01

This publication contains written versions of most of the invited talks presented at the workshop on Atomic Data Needs for X-ray Astronomy which was held at NASA's Goddard Space Flight Center on December 16-1 7 1999. The idea of hosting such a workshop emerged from an imminent need to update and complete current atomic datasets in anticipation of a new era of high quality X-ray spectra starting with the launching of Chandra and XMM-Newton observatories. At first, our vision of the workshop was of a short and limited attendance event, given the specialization of the topic. But it, was soon realized, from the response to the first workshop announcement, that the topic was of much interest, to researchers working in X-ray spectra (physicists and astronomers). As a result, the workshop grew to approximately 120 participants from several countries. The kind of atomic data that interests us are those parameters needed for analysis and modeling of spectra shortward of about about 100 A and relevant to ionic species of astronomical interest. The physical mechanisms of interest in the formation of spectra include photoionization. collisional ionization, recombination (radiative and dielectronic). collisional excitation (by electrons and protons). and radiative deexcitation. Unique to X-ray spectroscopy are the ionization and excitation processes from inner-closed shells. in addition to the challenges in interpret,ing the medium resolution (epsilon/delta epsilon is about 0.05 - 0.1) data obtained by current X-ray astronomy experiments. Line wavelengths are of interest too, particularly owing to the high resolution spectra from the new experiments. The workshop was divided into five major areas: Observational Spectroscopy, Theoretical Calculations of Atomic Data, Laboratory Measurements of Atomic Parameters. Spectra Modeling, and Atomic Databases. One comforting finding from the work shop is that the enthusiasm felt by X-ray astronomers about the new observational missions seems to be shared by theoretical and experimental physicists. Talks were presented about several exciting new projects and experimental and theoretical techniques devoted to X-ray spectroscopy. Simultaneously, several new tools for spectral analysis and modeling have recently been developed, together with improved atomic databases. These proceeding are expected to be of interests to producers and users of atomic data. Moreover. the contributions presented here have been written in a way that can be used by a general audience of scientists and graduate students in X-ray astronomy, modelling, and in computational and experimental atomic physics.

A Review of Issues Related to Data Acquisition and Analysis in EEG/MEG Studies.

PubMed

Puce, Aina; Hämäläinen, Matti S

2017-05-31

Electroencephalography (EEG) and magnetoencephalography (MEG) are non-invasive electrophysiological methods, which record electric potentials and magnetic fields due to electric currents in synchronously-active neurons. With MEG being more sensitive to neural activity from tangential currents and EEG being able to detect both radial and tangential sources, the two methods are complementary. Over the years, neurophysiological studies have changed considerably: high-density recordings are becoming de rigueur; there is interest in both spontaneous and evoked activity; and sophisticated artifact detection and removal methods are available. Improved head models for source estimation have also increased the precision of the current estimates, particularly for EEG and combined EEG/MEG. Because of their complementarity, more investigators are beginning to perform simultaneous EEG/MEG studies to gain more complete information about neural activity. Given the increase in methodological complexity in EEG/MEG, it is important to gather data that are of high quality and that are as artifact free as possible. Here, we discuss some issues in data acquisition and analysis of EEG and MEG data. Practical considerations for different types of EEG and MEG studies are also discussed.

An approach to the diagnosis of metabolic syndrome by the multi-electrode impedance method

NASA Astrophysics Data System (ADS)

Furuya, N.; Sakamoto, K.; Kanai, H.

2010-04-01

It is well known that metabolic syndrome can induce myocardial infarction and cerebral infarction. So, it is very important to measure the visceral fat volume. In the electric impedance method, information in the vicinity of the electrodes is strongly reflected. Therefore, we propose a new multi-electrode arrangement method based on the impedance sensitivity theorem to measure the visceral fat volume. This electrode arrangement is designed to enable high impedance sensitivity in the visceral and subcutaneous fat regions. Currents are simultaneously applied to several current electrodes on the body surface, and one voltage electrode pair is arranged on the body surface near the organ of interest to obtain the visceral fat information and another voltage electrode pair is arranged on the body surface near the current electrodes to obtain the subcutaneous fat information. A simulation study indicates that by weighting the impedance sensitivity distribution, as in our method, a high-sensitivity region in the visceral and the subcutaneous fat regions can be formed. In addition, it was confirmed that the visceral fat volume can be estimated by the measured impedance data.

42 CFR 438.320 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... ownership or investment interest no matter how many levels removed from a direct interest; or (2) A... consistent with current professional knowledge. Validation means the review of information, data, and...

The pathways of high school science teachers and policy efforts to alter the pipeline

NASA Astrophysics Data System (ADS)

Sass, Tim

2012-03-01

There is currently much interest in improving the quality of science education in K-12 schools and encouraging more students, particularly minorities and women, to pursue careers in STEM fields. Two interrelated issues are at the forefront: the quality of science teachers and the supply of science teachers. Education research in general finds that the single most important school-based factor affecting student achievement is teacher quality. While there is little evidence that teacher credentials matter for student achievement in the lower grades, there is at least some evidence that content knowledge is an important determinant of teacher quality in middle and secondary schools. However, little is known about the pre-service preparation of high school science teachers and how the training of science teachers affects their performance in the classroom. While there are many efforts underway to increase the supply of science teachers, little is known about the supply of science teachers from different pathways and the factors that lead science teachers to leave the profession. In this presentation I discuss recent work on the supply of teachers from alternative pathways, focusing on high school science teachers. I also summarize the literature on teacher quality and attrition, emphasizing the current state of knowledge on secondary school teachers. Finally, I present current policy initiatives and discuss the likelihood of their success given current research findings.

Guided exploration in virtual environments

NASA Astrophysics Data System (ADS)

Beckhaus, Steffi; Eckel, Gerhard; Strothotte, Thomas

2001-06-01

We describe an application supporting alternating interaction and animation for the purpose of exploration in a surround- screen projection-based virtual reality system. The exploration of an environment is a highly interactive and dynamic process in which the presentation of objects of interest can give the user guidance while exploring the scene. Previous systems for automatic presentation of models or scenes need either cinematographic rules, direct human interaction, framesets or precalculation (e.g. precalculation of paths to a predefined goal). We report on the development of a system that can deal with rapidly changing user interest in objects of a scene or model as well as with dynamic models and changes of the camera position introduced interactively by the user. It is implemented as a potential-field based camera data generating system. In this paper we describe the implementation of our approach in a virtual art museum on the CyberStage, our surround-screen projection-based stereoscopic display. The paradigm of guided exploration is introduced describing the freedom of the user to explore the museum autonomously. At the same time, if requested by the user, guided exploration provides just-in-time navigational support. The user controls this support by specifying the current field of interest in high-level search criteria. We also present an informal user study evaluating this approach.

Report from a forum on US heart allocation policy.

PubMed

Kobashigawa, J A; Johnson, M; Rogers, J; Vega, J D; Colvin-Adams, M; Edwards, L; Meyer, D; Luu, M; Reinsmoen, N; Dipchand, A I; Feldman, D; Kormos, R; Mancini, D; Webber, S

2015-01-01

Since the latest revision in US heart allocation policy (2006), the landscape and volume of transplant waitlists have changed considerably. Advances in mechanical circulatory support (MCS) prolong survival, but Status 1A mortality remains high. Several patient subgroups may be disadvantaged by current listing criteria and geographical disparity remains in waitlist time. This forum on US heart allocation policy was organized to discuss these issues and highlight concepts for consideration in the policy development process. A 25-question survey on heart allocation policy was conducted. Among attendees/respondents were 84 participants with clinical/published experience in heart transplant representing 51 US transplant centers, and OPTN/UNOS and SRTR representatives. The survey results and forum discussions demonstrated very strong interest in change to a further-tiered system, accounting for disadvantaged subgroups and lowering use of exceptions. However, a heart allocation score is not yet viable due to the long-term viability of variables (used in the score) in an ever-developing field. There is strong interest in more refined prioritization of patients with MCS complications, highly sensitized patients and those with severe arrhythmias or restrictive physiology. There is also strong interest in distribution by geographic boundaries modified according to population. Differences of opinion exist between small and large centers.

Disgust sensitivity and the 'non-rational' aspects of a career choice in surgery.

PubMed

Consedine, Nathan S; Yu, Tzu-Chieh; Hill, Andrew G; Windsor, John A

2013-03-15

Fitting trainee physicians to career paths remains an ongoing challenge in a highly fluid health workforce environment. Studies attempting to explain low interest in surgical careers have typically examined the relative impact of career and lifestyle values. The current work argues that emotional proclivities are potentially more important and that disgust sensitivity may help explain both low surgical interest as well as the tendency for female students to avoid surgical careers. 216 medical students attending a required course in human behaviour completed measures of career intention, traditional predictors of career intention and dispositional disgust sensitivity. As predicted, logistic regression showed that greater disgust sensitivity predicted lower surgical career intention even when controlling for traditional career values (OR=0.45, 95%CI=0.21-0.95). Additionally, the gender effect indexing low female interest in surgical careers was no longer significant once disgust sensitivity was added to the model. The impact of disgust sensitivity on surgical interest was substantial and on par with established predictors of career intention. Disgust sensitivity may represent a potentially modifiable factor impacting surgical career choice, particularly among female students who are typically more disgust sensitive.

Non-Inductively Driven Tokamak Plasmas at Near-Unity Toroidal Beta in the Pegasus Toroidal Experiment

NASA Astrophysics Data System (ADS)

Reusch, Joshua

2017-10-01

A major goal of the spherical tokamak research program is accessing a state of low internal inductance li, high elongation κ, high toroidal and normalized beta (βt and βN) , and low collisionality without solenoidal current drive. A new local helicity injection (LHI) system in the lower divertor region of the ultra-low aspect ratio Pegasus ST provides non-solenoidally driven plasmas that exhibit most of these characteristics. LHI utilizes compact, edge-localized current sources (Ainj 4 cm2, Iinj 8 kA, Vinj 1.5 kV) for plasma startup and sustainment, and can sustain more than 200 kA of plasma current. Plasma growth via LHI is enhanced by a transition from a regime of high kink-like MHD activity to one of reduced MHD activity at higher frequencies and presumably shorter wavelengths. The strong edge current drive provided by LHI results in a hollow current density profile with low li. The low aspect ratio (R0 / a 1.2) of Pegasus allows ready access to high κ and MHD stable operation at very high normalized plasma currents (IN =Ip /aBT> 15). Thomson scattering measurements indicate Te 100 eV and ne 1 ×19 m-3. The impurity Ti evolution is correlated in time with high frequency magnetic fluctuations, implying substantial reconnection ion heating is driven by the applied helicity injection. Doppler spectroscopy indicates Ti >=Te and that the anomalous ion heating scales consistently with two fluid reconnection theory. Taken together, these features provide access to very high βt plasmas. Equilibrium analyses indicate βt up to 100% and βN 6.5 is achieved. At increasingly low BT, the discharge disrupts at the no-wall ideal stability limit. In these high βt discharges, a minimum |B| well forms over 50% of the plasma volume. This unique magnetic configuration may be of interest for testing predictions of stabilizing drift wave turbulence and/or improving energetic particle confinement. This work supported by US DOE Grants DE-FG02-96ER54375 and DE-SC0006928.

Optimization of the Costs and the Safety of Maritime Transport by Routing: The use of Currents Forecast in the Routing of Racing Sail Boats as a Prototype of Rout Optimization for Trading Ships

NASA Astrophysics Data System (ADS)

Theunynck, Denis; Peze, Thierry; Toumazou, Vincent; Zunquin, Gauthier; Cohen, Olivier; Monges, Arnaud

2005-03-01

It is interesting to see whether the model of routing designed for races and great Navy operations could be transferred to commercial navigation and if so, within which framework.Sail boat routing conquered its letters of nobility during great races like the « Route du Rhum » or the transatlantic race « Jacques Vabre ». It is the ultimate stage of the step begun by the Navy at the time of great operations, like D-day (Overlord )June 6, 1944, in Normandy1.Routing is, from the beginning, mainly based on statistical knowledge and weather forecast, but with the recent availability of reliable currents forecast, sail boats routers and/or skippers now have to learn how to use both winds and currents to obtain the best performance, that is to travel between two points in the shortest time possible in acceptable security conditions.Are the currents forecast only useful to racing sail boat ? Of course not, they are a great help to fisherman for whom the knowledge of currents is also the knowledge of sea temperature who indicates the probability of fish presence. They are also used in offshore work to predict the hardness of the sea during operation.A less developed field of application is the route optimization of trading ships. The idea is to optimize the use of currents to increase the relative speed of ships with no augmentation of fuel expense. This new field will require that currents forecasters learn about the specific needs of another type of clients. There is also a need of teaching because the future customers will have to learn how to use the information they will get.At this point, the introduction of the use of currents forecast in racing sail boats routing is only the first step. It is of great interest because it can rely on a high knowledge in routing.The main difference is of course that the wind direction and its force are of greater importance to a sail boat that they are for a trading ship for whom the point of interest will be the fuel consumption and the ETA respect.Despite that, sail boat routing could be use as a prototype to determine the needs, both in term of information and formations of ship routers and skippers2.

Fabrication of high responsivity deep UV photo-detector based on Na doped ZnO nanocolumns

NASA Astrophysics Data System (ADS)

Agrawal, Jitesh; Dixit, Tejendra; Palani, I. A.; Ramachandra Rao, M. S.; Singh, Vipul

2018-05-01

We report a variety of the hydrothermally synthesized ZnO nanostructures with a significant suppression in defect-related emission and huge enhancement in the photo-current to the dark current ratio (approximately six orders of magnitude) upon UV light illumination. Interestingly, the photo-detector shows lower dark current of 1.6 nA with high responsivity of 507 A W‑1 at 254 nm. Here, a systematic analysis of the growth process as well as the physical, chemical and electrical properties of as-grown ZnO nanostructures has been performed. We have utilized the duo effect of both the inorganic (KMnO4) and organic (Na3C6H5O7) additives, which has facilitated the precise tuning of the morphology and intrinsic defects in nanostructures that have made an impact on the photo-responsivity, photoluminescence (PL) and adhesivity of the film on to the underlying substrate. PL analysis of as-grown ZnO nanostructures has suggested 11 times improvement in the near band emission (NBE) to defect level emission (DLE) ratio. Interestingly, thermal annealing of the samples has shown a dramatic change in the morphology with significant improvement in the crystallinity. Notably, the band gap was observed to be modulated from 3.3 eV to 3.1 eV after annealing. In addition to UV photo-detector based applications, the work presented here has provided a subtle solution towards the rectification of various problems pertaining to hydrothermal processes like poor adhesivity, feeble UV emission and problem in precise tuning of the morphology along with the bandgap in one go. Therefore, these investigations assume critical significance towards the development of next-generation optoelectronic devices.

Prenatal factors associated with birth weight and length and current nutritional status of hospitalized children aged 4-24 months.

PubMed

Mariante Giesta, Juliana; Ramón da Rosa, Suélen; Moura Pessoa, Juliana Salino; Lúcia Bosa, Vera

2015-06-01

The objective of the present study was to investigate the associations of prenatal factors with birth weight and length, as well as current nutritional status, of children hospitalized in southern Brazil. We conducted a cross-sectional study of 300 child-mother pairs. Children were between 4 and 24 months old. They were at the inpatient unit or pediatric emergency department of the Hospital de Clínicas de Porto Alegre. Anthropometric data were collected, and a questionnaire on gestational data was answered by the children's mothers. Maternal variables of interest were: prepregnancy body mass index (BMI), gestational weight gain, smoking and/or use of alcohol, use of illicit drugs, gestational diabetes and/ or high blood pressure. Children's variables of interest were: sex, gestational age, birth weight (BW) and birth length (BL), and current anthropometric data [body mass index for age (BMI/A), height for age (H/A), and weight for age (W/A)]. The gestational weight gain and smoking were associated with BW. We also found that H/A was associated with BW and BL, W/A was associated with BW, and BMI/A was associated with BL. The gestational weight gain was associated with BL, diabetes was associated with BW and BL, and high blood pressure was associated with low height in the first two years of life. We concluded that prenatal factors may have an influence on both BW and BL, causing the birth of small and large for gestational age children, and thus affecting their growth rate during the first years of life. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

Communication Professionals: A New Market for Continuing Higher Education.

ERIC Educational Resources Information Center

Miller, Debra A.; Rose, Patricia B.

1995-01-01

A survey of 1,058 American Advertising Federation members and 806 Public Relations Society of America members (564 total responses) revealed widespread interest in continuing education in the form of seminars and workshops to keep current and advance. Interest in degree programs decreased with years of experience. Topic interests included…

78 FR 42572 - Self-Regulatory Organizations; Chicago Mercantile Exchange Inc.; Notice of Filing and Immediate...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-16

... Change Regarding Interest Rate Swap Clearing Changes July 10, 2013. Pursuant to Section 19(b)(1) of the... a derivatives clearing organization offering interest rate swap (``IRS'') clearing services. More... the Commodity Futures Trading Commission and currently offers clearing services for interest rate...

30 CFR 870.21 - Late payments.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Government. The Treasury current value of funds rate is published annually in the Federal Register and on... fees and interest. (c) When a reclamation fee debt is more than 91 days overdue, a 6 percent annual... fee was owed are subject to interest. Late reclamation fee payments are subject to interest at the...

Developing "Emancipatory Interest": Learning to Create Social Change

ERIC Educational Resources Information Center

Caspersz, Donella; Olaru, Doina

2014-01-01

Developing an emancipatory interest enables individuals to free themselves from the intersubjective or commonly held meanings that dominate their understanding of their current world, and subsequently change their practices. We argue that developing an emancipatory interest is critical in learning to create social change, that is, wanting to…

77 FR 50730 - Self-Regulatory Organizations; Chicago Mercantile Exchange, Inc.; Notice of Filing and Order...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-22

... (``CFTC''), and currently operates a substantial business clearing both IRS and interest rate futures... Proposed Rule Change To Amend Rules To Facilitate Customer Portfolio Margining of Interest Rate Futures and...'') and interest rate futures clearing offerings by establishing a portfolio margining program for...

Magnetoacoustic Tomography with Magnetic Induction for Electrical Conductivity based Tissue imaging

NASA Astrophysics Data System (ADS)

Mariappan, Leo

Electrical conductivity imaging of biological tissue has attracted considerable interest in recent years owing to research indicating that electrical properties, especially electrical conductivity and permittivity, are indicators of underlying physiological and pathological conditions in biological tissue. Also, the knowledge of electrical conductivity of biological tissue is of interest to researchers conducting electromagnetic source imaging and in design of devices that apply electromagnetic energy to the body such as MRI. So, the need for a non-invasive, high resolution impedance imaging method is highly desired. To address this need we have studied the magnetoacoustic tomography with magnetic induction (MAT-MI) method. In MAT-MI, the object is placed in a static and a dynamic magnetic field giving rise to ultrasound waves. The dynamic field induces eddy currents in the object, and the static field leads to generation of acoustic vibrations from Lorentz force on the induced currents. The acoustic vibrations are at the same frequency as the dynamic magnetic field, which is chosen to match the ultrasound frequency range. These ultrasound signals can be measured by ultrasound probes and are used to reconstruct MAT-MI acoustic source images using possible ultrasound imaging approaches .The reconstructed high spatial resolution image is indicative of the object's electrical conductivity contrast. We have investigated ultrasound imaging methods to reliably reconstruct the MAT-MI image under the practical conditions of limited bandwidth and transducer geometry. The corresponding imaging algorithm, computer simulation and experiments are developed to test the feasibility of these different methods. Also, in experiments, we have developed a system with the strong static field of an MRI magnet and a strong pulsed magnetic field to evaluate MAT-MI in biological tissue imaging. It can be seen from these simulations and experiments that conductivity boundary images with millimeter resolution can be reliably reconstructed with MAT-MI. Further, to estimate the conductivity distribution throughout the object, we reconstruct a vector source image corresponding to the induced eddy currents. As the current source is uniformly present throughout the object, we are able to reliably estimate the internal conductivity distribution for a more complete imaging. From the computer simulations and experiments it can be seen that MAT-MI method has the potential to be a clinically applicable, high resolution, non-invasive method for electrical conductivity imaging.

Creating a pipeline of talent for informatics: STEM initiative for high school students in computer science, biology, and biomedical informatics

PubMed Central

Dutta-Moscato, Joyeeta; Gopalakrishnan, Vanathi; Lotze, Michael T.; Becich, Michael J.

2014-01-01

This editorial provides insights into how informatics can attract highly trained students by involving them in science, technology, engineering, and math (STEM) training at the high school level and continuing to provide mentorship and research opportunities through the formative years of their education. Our central premise is that the trajectory necessary to be expert in the emergent fields in front of them requires acceleration at an early time point. Both pathology (and biomedical) informatics are new disciplines which would benefit from involvement by students at an early stage of their education. In 2009, Michael T Lotze MD, Kirsten Livesey (then a medical student, now a medical resident at University of Pittsburgh Medical Center (UPMC)), Richard Hersheberger, PhD (Currently, Dean at Roswell Park), and Megan Seippel, MS (the administrator) launched the University of Pittsburgh Cancer Institute (UPCI) Summer Academy to bring high school students for an 8 week summer academy focused on Cancer Biology. Initially, pathology and biomedical informatics were involved only in the classroom component of the UPCI Summer Academy. In 2011, due to popular interest, an informatics track called Computer Science, Biology and Biomedical Informatics (CoSBBI) was launched. CoSBBI currently acts as a feeder program for the undergraduate degree program in bioinformatics at the University of Pittsburgh, which is a joint degree offered by the Departments of Biology and Computer Science. We believe training in bioinformatics is the best foundation for students interested in future careers in pathology informatics or biomedical informatics. We describe our approach to the recruitment, training and research mentoring of high school students to create a pipeline of exceptionally well-trained applicants for both the disciplines of pathology informatics and biomedical informatics. We emphasize here how mentoring of high school students in pathology informatics and biomedical informatics will be critical to assuring their success as leaders in the era of big data and personalized medicine. PMID:24860688

Creating a pipeline of talent for informatics: STEM initiative for high school students in computer science, biology, and biomedical informatics.

PubMed

Dutta-Moscato, Joyeeta; Gopalakrishnan, Vanathi; Lotze, Michael T; Becich, Michael J

2014-01-01

This editorial provides insights into how informatics can attract highly trained students by involving them in science, technology, engineering, and math (STEM) training at the high school level and continuing to provide mentorship and research opportunities through the formative years of their education. Our central premise is that the trajectory necessary to be expert in the emergent fields in front of them requires acceleration at an early time point. Both pathology (and biomedical) informatics are new disciplines which would benefit from involvement by students at an early stage of their education. In 2009, Michael T Lotze MD, Kirsten Livesey (then a medical student, now a medical resident at University of Pittsburgh Medical Center (UPMC)), Richard Hersheberger, PhD (Currently, Dean at Roswell Park), and Megan Seippel, MS (the administrator) launched the University of Pittsburgh Cancer Institute (UPCI) Summer Academy to bring high school students for an 8 week summer academy focused on Cancer Biology. Initially, pathology and biomedical informatics were involved only in the classroom component of the UPCI Summer Academy. In 2011, due to popular interest, an informatics track called Computer Science, Biology and Biomedical Informatics (CoSBBI) was launched. CoSBBI currently acts as a feeder program for the undergraduate degree program in bioinformatics at the University of Pittsburgh, which is a joint degree offered by the Departments of Biology and Computer Science. We believe training in bioinformatics is the best foundation for students interested in future careers in pathology informatics or biomedical informatics. We describe our approach to the recruitment, training and research mentoring of high school students to create a pipeline of exceptionally well-trained applicants for both the disciplines of pathology informatics and biomedical informatics. We emphasize here how mentoring of high school students in pathology informatics and biomedical informatics will be critical to assuring their success as leaders in the era of big data and personalized medicine.

A phenomenological analysis of the essence of the science education experience as perceived by female high school physics and advanced chemistry students

NASA Astrophysics Data System (ADS)

Papadimitriou, Michael

The purpose of this phenomenological study was to describe the essential elements of the current science education experience as constructed by twelve female high school physics and advanced chemistry students. The expressed desired outcome was a description of the phenomenon from a participant point of view. Student recollections and interpretations of experiences were assessed for a twelve-week period. Data sources were student journals, autobiographies, interviews, focus group interviews and researcher observations. In addition, each participant completed the Test of Science Related Attitudes (Fraser, 1981) in order to create attitude profiles for triangulation with other data. While a wide range of aspects of the science education experience emerged, results showed that female students describe and interpret their science education experiences on the basis of actual interest in science, early science experiences, perception of ability, self-confidence, teacher attributes, parental and peer interaction, societal expectations, the nature of science, and gender. Of these factors, specifically, interest and curiosity, societal influence, the nature of science, lack of in-school experiences, the desire to help others, and general parent support were most impacting upon experience and the desire to continue science study. Moreover, the interaction of these factors is relevant. Very simply, early experiences are crucial to interest development. In general, parents can enhance this interest by providing science-related experiences. In the absence of early in-school experiences (i.e., which the participants reported), these out-of-school experiences become crucial. More importantly, quality instruction and parent and peer support are needed to foster science interest and to overcome the powerfully negative influence of society, the discriminatory nature of science, and the lack of experiences.

The influence and ethics of interest groups on policy incentives for clean energy development

NASA Astrophysics Data System (ADS)

Maguire, Mariana C.

The clean energy revolution in the United States is not going to happen until diverse stakeholders in the coalition of clean energy proponents strengthen their cohesion and influence—two critical tools for interest group's to be successful in driving the formulation of public policy. Currently, clean energy technology and resource development is supported by a highly diverse coalition of interest groups such as environmental groups, health organizations, industry, and the Defense Department, whose primary goals are often unrelated. Yet their objectives are increasingly well served by pursuing clean energy development by pushing lawmakers for supportive policies. However, characteristics of this ad hoc coalition can hinder its influence and cohesion. Whereas, fossil fuel interests—exemplified by the coalition of oil proponents—are highly cohesive and influential. This thesis will analyze whether there is a correlation between public policies on clean energy, and the strength of interest group influence over those policy decisions. It will begin with an analysis of interest group theories. Next it will analyze the histories of the oil industry as the model opponent of clean energy policies, and the biofuels, wind energy, and solar energy industries as the model proponents of clean energy policies. The composition of the respective coalitions will reveal if they are diverse or similar, with broad or narrow goals, and other important characteristics. Their respective policy positions and messages will show what values are important to them, and the presidential support each coalition has been achieved, or failed to achieve, will provide further insight into their effectiveness. This thesis will then apply interest group theories to the supporter and opponent coalitions. Results obtained indicate that the coalition of oil interests is large, yet very cohesive and influential, while the coalition for clean energy is large, generally diffuse but with some important signs of cohesion, and relatively influential. Therefore this analysis concludes that the clean energy coalition must strengthen itself in areas that produce cohesion, such as encouraging partnerships with stakeholders with asymmetrical interests, and increase its financial influence in order to leverage more resources toward influencing policymakers to promote clean energy development.

78 FR 64183 - Change to Existing Regulation Concerning the Interest Rate Paid on Cash Deposited To Secure...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-28

... Account. These funds are held ``in trust'' for the obligor and currently earn simple interest at the rate..., the Government has paid simple interest at the rate of 3 percent per year on cash deposited by bond... #0;notices is to give interested persons an opportunity to participate in #0;the rule making prior to...

Harm reduction and cessation efforts and interest in cessation resources among survivors of smoking-related cancers.

PubMed

Berg, Carla J; Carpenter, Matthew J; Jardin, Bianca; Ostroff, Jamie S

2013-03-01

Despite the well-established risks associated with persistent smoking, many cancer survivors who were active smokers at the time of cancer diagnosis continue to smoke. In order to guide the development of tobacco cessation interventions for cancer survivors, a better understanding is needed regarding post-diagnosis quitting efforts. Thus, we examined quitting and reduction efforts and interest in cessation resources among cancer survivors who self-identified as current smokers at the time of diagnosis. We conducted analyses of survey participants (n = 54) who were current smokers at the time of cancer diagnosis and were continued smokers at the time of assessment. We also conducted semi-structured interviews (n = 21) among a subset of those who either continued to smoke or quit smoking post-cancer diagnosis. Among our survey participants, 22.2 % had ever used behavioral cessation resources and 66.7 % had use pharmacotherapy, while 62.8 % had interest in future use of behavioral cessation resources and 75.0 % had interest in pharmacotherapy. The majority reported some quitting efforts including making quit attempts, using cessation medications, and reducing their daily cigarette consumption. Semi-structured interview data revealed various strategies used to aid in smoking reduction and cessation as well as variability in preferences for cessation resources. Cancer patients who smoke following diagnosis often engage in smoking reduction and cessation-related behaviors, which may reflect their motivation to reduce their smoking-related risks. They also report high interest in cessation resources. Thus, it is important to explore the acceptability and effectiveness of different cessation intervention components among this group. Cancer survivors who smoke demonstrate actions toward harm reduction and cessation. They should inquire about potential resources that might facilitate their efforts among their healthcare providers and enlist support and advice from others around them to bolster their efforts.

A Cross-sectional Examination of What Smokers Perceive to be Important and Their Willingness to Pay for Tobacco Cessation Medications.

PubMed

Dube, Shanta R; Pesko, Michael F; Xu, Xin

2016-01-01

Tobacco smoking is the leading cause of preventable morbidity and mortality in the United States, and smoking cessation has multiple health benefits. The purpose of this study was to assess cigarette smokers' perceived importance toward characteristics of tobacco cessation medications using a willingness-to-pay approach. Cross-sectional analysis of data from the 2008 HealthStyles survey, a mail-based probability sample of 5399 adults aged 18 years and older.Point estimates and 95% confidence intervals were calculated overall and by sociodemographic and smoking behavior characteristics. Multivariate Probit regression analysis was used to evaluate smokers' willingness to pay in relation to perceived importance of 3 cessation medication characteristics: convenience of use, over-the-counter availability, and efficiency to help quit. All models controlled for sociodemographic characteristics, smoking behavior characteristics, and US regional fixed effects. A total of 914 current cigarette smokers. Interest in quitting, interest in using cessation medications, and willingness to pay for 6 types of cessation medications. Approximately 68.4% of current cigarette smokers were interested in quitting. Among these individuals, 45.6% indicated that they were interested in using cessation medications, and of these, 47.3% indicated that they were willing to pay $150 or more out-of-pocket for these medications. Convenience of use and the effectiveness of these medications to help quit were positively associated with current smokers' willingness to pay for $300 or more (P < .05); however, no association was observed for over-the-counter availability. Self-reported exposure to telephone quitline advertisements was also positively associated with the willingness to pay. Approximately 68% of current smokers are interested in quitting, and about half of those smokers interested in quitting are also interested in using cessation medications. Convenience of use and the medication's effectiveness are important characteristics of cessation medication for smokers with quit intentions. Understanding preferences for these cessation medication characteristics may help inform smoking cessation efforts.

NASA Efforts on Nanotechnology

NASA Technical Reports Server (NTRS)

Miranda, Felix A.

2003-01-01

An overview of the field of nanotechnology within the theme of "New efforts in Nanotechnology Research," will be presented. NASA's interest, requirements and current efforts in this emerging field will be discussed. In particular, NASA efforts to develop nanoelectronic devices, fuel cells, and other applications of interest using this novel technology by collaborating with academia will be addressed. Progress on current collaborations in this area with the University of Puerto Rico will be highlighted.

Long-term high-intensity sound stimulation inhibits h current (Ih ) in CA1 pyramidal neurons.

PubMed

Cunha, A O S; Ceballos, C C; de Deus, J L; Leão, R M

2018-05-19

Afferent neurotransmission to hippocampal pyramidal cells can lead to long-term changes to their intrinsic membrane properties and affect many ion currents. One of the most plastic neuronal currents is the hyperpolarization activated cationic current (I h ), which changes in CA1 pyramidal cells in response to many types of physiological and pathological processes, including auditory stimulation. Recently we demonstrated that long-term potentiation (LTP) in rat hippocampal Schaffer-CA1 synapses is depressed by high-intensity sound stimulation. Here we investigated if a long-term high-intensity sound stimulation could affect intrinsic membrane properties of rat CA1 pyramidal neurons. Our results showed that I h is depressed by long-term high intensity sound exposure (1 minute of 110 dB sound, applied two times per day for 10 days). This resulted in a decreased resting membrane potential, increased membrane input resistance and time constant, and decreased action potential threshold. In addition, CA1 pyramidal neurons from sound-exposed animals fired more action potentials than neurons from control animals; However, this effect was not caused by a decreased I h . Interestingly, a single episode (1 minute) of 110 dB sound stimulation which also inhibits hippocampal LTP did not affect I h and firing in pyramidal neurons, suggesting that effects on I h are long-term responses to high intensity sound exposure. Our results show that prolonged exposure to high-intensity sound affects intrinsic membrane properties of hippocampal pyramidal neurons, mainly by decreasing the amplitude of I h . This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

CRADA Final Report: Application of Dual-Mode Inverter Control to Commercially Available Radial-Gap Mermanent Magnet Motors - Vol. I

DOE Office of Scientific and Technical Information (OSTI.GOV)

McKeever, John W; Lawler, Jack; Downing, Mark

2006-05-01

John Deere and Company (Deere), their partner, UQM Technologies, Inc. (UQM), and the Oak Ridge National Laboratory's (ORNL's) Power Electronics and Electric Machinery Research Center (PEEMRC) recently completed work on the cooperative research and development agreement (CRADA) Number ORNL 04-0691 outlined in this report. CRADA 04-0691 addresses two topical issues of interest to Deere: (1) Improved characterization of hydrogen storage and heat-transfer management; and (2) Potential benefits from advanced electric motor traction-drive technologies. This report presents the findings of the collaborative examination of potential operational and cost benefits from using ORNL/PEEMRC dual-mode inverter control (DMIC) to drive permanent magnet (PM)more » motors in applications of interest to Deere. DMIC was initially developed and patented by ORNL to enable PM motors to be driven to speeds far above base speed where the back-electromotive force (emf) equals the source voltage where it is increasingly difficult to inject current into the motor. DMIC is a modification of conventional phase advance (CPA). DMIC's dual-speed modes are below base speed, where traditional pulse-width modulation (PWM) achieves maximum torque per ampere (amp), and above base speed, where six-step operation achieves maximum power per amp. The modification that enables DMIC adds two anti-parallel thyristors in each of the three motor phases, which consequently adds the cost of six thyristors. Two features evaluated in this collaboration with potential to justify the additional thyristor cost were a possible reduction in motor cost and savings during operation because of higher efficiency, both permitted because of lower current. The collaborative analysis showed that the reduction of motor cost and base cost of the inverter was small, while the cost of adding six thyristors was greater than anticipated. Modeling the DMIC control displayed inverter efficiency gains due to reduced current, especially under light load and higher speed. This current reduction, which is the salient feature of DMIC, may be significant when operating duty cycles have low loads at high frequencies. Reduced copper losses make operation more efficient thereby reducing operating costs. In the Deere applications selected for this study, the operating benefit was overshadowed by the motor's rotational losses. Rotational losses of Deere 1 and Deere 2 dominate the overall drive efficiency so that their reduction has the greatest potential to improve performance. A good follow-up project would be to explore cost erective ways to reduce the rotational losses buy 66%. During this analysis it has been shown that, for a PM synchronous motor (PMSM), the DMIC's salient feature is its ability to minimize the current required to deliver a given power. The root-mean-square (rms) current of a motor is determined by the speed, power, motor drive parameters, and controls as I{sub rms} = (n, P, motor drive parameters, controls), where n is the relative speed, {omega}/{omega}{sub base} = {Omega}/{Omega}{sub base}, {omega} is the mechanical frequency, {Omega} is the electrical frequency, and P is the power. The characteristic current is the rms current at infinite speed, when all resistance and rotational losses are neglected. Expressions have been derived for the characteristic currents of PMSMs when the motor is controlled by CPA and by DMIC. The expression for CPA characteristic current is I{sub n{yields}{infinity}}{sup CPA} = nE{sub base}/X = nE{sub base}/n{Omega}{sub b}L = E{sub base}/{Omega}{sub b}L, which is strictly a function of the machine parameters, back-emf at base speed, base speed electrical frequency, and inductance. At high speeds, the rms current tends to remain constant even when the load-power requirements are reduced. The expression for DMIC characteristic current is I{sub n{yields}{infinity}}{sup DMIC} = P/3V{sub max} = P{pi}/3{radical}2V{sub dc}, which has nothing to do with machine parameters. This interesting result shows that at high speeds under DMIC control, the rms current diminishes as the load-power requirements are reduced. It also shows that the DMIC characteristic current can be further reduced by increasing the dc supply voltage. This explains the main benefit of DMIC; its ability to minimize the current required to meet a required load.« less

CNTs grown on nanoporous carbon from zeolitic imidazolate frameworks for supercapacitors.

PubMed

Kim, Jeonghun; Young, Christine; Lee, Jaewoo; Park, Min-Sik; Shahabuddin, Mohammed; Yamauchi, Yusuke; Kim, Jung Ho

2016-10-27

Carbon nanotubes (CNT) grown on nanoporous carbon (NPC), which yields coexisting amorphous and graphitic nanoarchitectures, have been prepared on a large scale from zeolitic imidazolate framework (ZIF) by introducing bimetallic ions (Co 2+ and Zn 2+ ). Interestingly, the hybrid Co/Zn-ZIF-derived NPC showed rich graphitic CNTs on the surface. This NPC was utilized for a coin-type supercapacitor cell with an aqueous electrolyte, which showed enhanced retention at high current density and good stability over 10 000 cycles.

DOE Office of Scientific and Technical Information (OSTI.GOV)

RF Kristensen; JF Beausang; DM DePoy

Frequency selective surfaces (FSS) effectively filter electromagnetic radiation in the microwave band (1 mm to 100 mm). Interest exists in extending this technology to the near infrared (1 {micro}m to 10 {micro}m) for use as a filter of thermal radiation in thermophotovoltaic (TPV) direct energy conversion. This paper assesses the ability of FSS to meet the strict spectral performance requirements of a TPV system. Inherent parasitic absorption, which is the result of the induced currents in the FSS metallization, is identified as a significant obstacle to achieving high spectral performance.

Towards a dispersive determination of the pion transition form factor

NASA Astrophysics Data System (ADS)

Leupold, Stefan; Hoferichter, Martin; Kubis, Bastian; Niecknig, Franz; Schneider, Sebastian P.

2018-01-01

We start with a brief motivation why the pion transition form factor is interesting and, in particular, how it is related to the high-precision standard-model calculation of the gyromagnetic ratio of the muon. Then we report on the current status of our ongoing project to calculate the pion transition form factor using dispersion theory. Finally we present and discuss a wish list of experimental data that would help to improve the input for our calculations and/or to cross-check our results.

Wind tunnel wall interference

NASA Technical Reports Server (NTRS)

Newman, Perry A.; Mineck, Raymond E.; Barnwell, Richard W.; Kemp, William B., Jr.

1986-01-01

About a decade ago, interest in alleviating wind tunnel wall interference was renewed by advances in computational aerodynamics, concepts of adaptive test section walls, and plans for high Reynolds number transonic test facilities. Selection of NASA Langley cryogenic concept for the National Transonic Facility (NTF) tended to focus the renewed wall interference efforts. A brief overview and current status of some Langley sponsored transonic wind tunnel wall interference research are presented. Included are continuing efforts in basic wall flow studies, wall interference assessment/correction procedures, and adaptive wall technology.

Recent developments in stereoscopic and holographic 3D display technologies

NASA Astrophysics Data System (ADS)

Sarma, Kalluri

2014-06-01

Currently, there is increasing interest in the development of high performance 3D display technologies to support a variety of applications including medical imaging, scientific visualization, gaming, education, entertainment, air traffic control and remote operations in 3D environments. In this paper we will review the attributes of the various 3D display technologies including stereoscopic and holographic 3D, human factors issues of stereoscopic 3D, the challenges in realizing Holographic 3D displays and the recent progress in these technologies.

Contracting Officer's Technical Representatives

NASA Technical Reports Server (NTRS)

Brisbin, Steve

1997-01-01

The Breakout Session is a traditional conference instrument used by the NASA Occupational Health Program (OHP) as a method to convene people with common interests. Typically these sessions provide discussion of current topics of high priority and currency and allow multiple views and opinions to be shared and evaluated by all participants. Since the Contracting Officer's Technical Representatives (COTRs) occupy the technical focus of support contract management, this particular group, attended by 20 representatives, addressed issues and topics at the forefront of operational concerns.

Porous Shape Memory Polymers

PubMed Central

Hearon, Keith; Singhal, Pooja; Horn, John; Small, Ward; Olsovsky, Cory; Maitland, Kristen C.; Wilson, Thomas S.; Maitland, Duncan J.

2013-01-01

Porous shape memory polymers (SMPs) include foams, scaffolds, meshes, and other polymeric substrates that possess porous three-dimensional macrostructures. Porous SMPs exhibit active structural and volumetric transformations and have driven investigations in fields ranging from biomedical engineering to aerospace engineering to the clothing industry. The present review article examines recent developments in porous SMPs, with focus given to structural and chemical classification, methods of characterization, and applications. We conclude that the current body of literature presents porous SMPs as highly interesting smart materials with potential for industrial use. PMID:23646038

150 years of Sigmund Freud: What would Freud have said about the obesity epidemic?

PubMed

Bornstein, S R; Wong, M-L; Licinio, J

2006-12-01

The 150th birthday of Sigmund Freud has triggered widespread interest and media coverage on his unique contribution and impact on society. Recent evidence from neuroscience and advanced imaging technology has provided support for some of his major concepts including the unconscious and the key role of early life events. In this perspective, we attempt to write on his behalf an updated version of a Freudian way of thinking focused on the current high rates of obesity and depression.

Sensitivity Analysis of Fatigue Crack Growth Model for API Steels in Gaseous Hydrogen.

PubMed

Amaro, Robert L; Rustagi, Neha; Drexler, Elizabeth S; Slifka, Andrew J

2014-01-01

A model to predict fatigue crack growth of API pipeline steels in high pressure gaseous hydrogen has been developed and is presented elsewhere. The model currently has several parameters that must be calibrated for each pipeline steel of interest. This work provides a sensitivity analysis of the model parameters in order to provide (a) insight to the underlying mathematical and mechanistic aspects of the model, and (b) guidance for model calibration of other API steels.

Optoelectronics Material Center: A Collaborative Program Including Center for High Technology Materials of the University of New Mexico, Stanford University, California Institute of Technology

DTIC Science & Technology

1992-09-01

SI by Ion-Assisted Molecular Beam Enltaxy Currently there is considerable interest in misfit accommodation in hetero- epitaxy for integration of device...of misfit accommodation. In the last quarter, we have demonstrated, using ion-assisted molecular beam epitaxy : * Reduction of dislocation density in... beam epitaxy (MOMBE) hardware, and demonstration of state-of-the-art MOMBE AlGaAs (1990). MOCVD Materials Growth Facilities and Eauipment Extension to

Current Technology for Thermal Protection Systems

NASA Technical Reports Server (NTRS)

Scotti, Stephen J. (Compiler)

1992-01-01

Interest in thermal protection systems for high-speed vehicles is increasing because of the stringent requirements of such new projects as the Space Exploration Initiative, the National Aero-Space Plane, and the High-Speed Civil Transport, as well as the needs for improved capabilities in existing thermal protection systems in the Space Shuttle and in turbojet engines. This selection of 13 papers from NASA and industry summarizes the history and operational experience of thermal protection systems utilized in the national space program to date, and also covers recent development efforts in thermal insulation, refractory materials and coatings, actively cooled structures, and two-phase thermal control systems.

Computer aided drug discovery of highly ligand efficient, low molecular weight imidazopyridine analogs as FLT3 inhibitors

PubMed Central

Frett, Brendan; McConnell, Nick; Smith, Catherine C.; Wang, Yuanxiang; Shah, Neil P.; Li, Hong-yu

2015-01-01

The FLT3 kinase represents an attractive target to effectively treat AML. Unfortunately, no FLT3 targeted therapeutic is currently approved. In line with our continued interests in treating kinase related disease for anti-FLT3 mutant activity, we utilized pioneering synthetic methodology in combination with computer aided drug discovery and identified low molecular weight, highly ligand efficient, FLT3 kinase inhibitors. Compounds were analyzed for biochemical inhibition, their ability to selectively inhibit cell proliferation, for FLT3 mutant activity, and preliminary aqueous solubility. Validated hits were discovered that can serve as starting platforms for lead candidates. PMID:25765758

Defending Against Smallpox: a Focus on Vaccines

PubMed Central

Voigt, Emily A.; Kennedy, Richard B.; Poland, Gregory A.

2016-01-01

Smallpox has shaped human history, from the earliest human civilizations well into the 20th century. With high mortality rates, rapid transmission, and serious long-term effects on survivors, smallpox was a much-feared disease. The eradication of smallpox represents an unprecedented medical victory for the lasting benefit of human health and prosperity. Concerns remain, however, about the development and use of the smallpox virus as a biological weapon, which necessitates the need for continued vaccine development. Smallpox vaccine development is thus a much-reviewed topic of high interest. This review focuses on the current state of smallpox vaccines and their context in biodefense efforts. PMID:27049653

Defending against smallpox: a focus on vaccines.

PubMed

Voigt, Emily A; Kennedy, Richard B; Poland, Gregory A

2016-09-01

Smallpox has shaped human history, from the earliest human civilizations well into the 20th century. With high mortality rates, rapid transmission, and serious long-term effects on survivors, smallpox was a much-feared disease. The eradication of smallpox represents an unprecedented medical victory for the lasting benefit of human health and prosperity. Concerns remain, however, about the development and use of the smallpox virus as a biological weapon, which necessitates the need for continued vaccine development. Smallpox vaccine development is thus a much-reviewed topic of high interest. This review focuses on the current state of smallpox vaccines and their context in biodefense efforts.

Nondestructive evaluation of nuclear-grade graphite

NASA Astrophysics Data System (ADS)

Kunerth, D. C.; McJunkin, T. R.

2012-05-01

The material of choice for the core of the high-temperature gas-cooled reactors being developed by the U.S. Department of Energy's Next Generation Nuclear Plant Program is graphite. Graphite is a composite material whose properties are highly dependent on the base material and manufacturing methods. In addition to the material variations intrinsic to the manufacturing process, graphite will also undergo changes in material properties resulting from radiation damage and possible oxidation within the reactor. Idaho National Laboratory is presently evaluating the viability of conventional nondestructive evaluation techniques to characterize the material variations inherent to manufacturing and in-service degradation. Approaches of interest include x-ray radiography, eddy currents, and ultrasonics.

Planning for success: desired characteristics of special operations surgeons, a pilot study.

PubMed

Campbell, Barrett H; Alderman, Shawn M

2012-01-01

Selection criteria for Special Operations Forces (SOF) physicians are often unclear to potential candidates without prior SOF experience. To date, no published career resource exists to guide the careers of physicians interested in becoming a SOF surgeon. Using a survey tool, desirable characteristics and personal attributes were identified that can be used to inform candidate career decisions and better prepare them for a future position in Special Operations. A descriptive, cross-sectional survey instrument was developed and distributed to current Army SOF Command Surgeons for further distribution to subordinate surgeons. RESULTS were analyzed as a cohort and by subordinate command. Respondents consisted of current SOF Surgeons. Uniformly, the individual characteristics most strongly desired are professionalism, being a team player, and leadership. Possessing or obtaining Airborne and Flight Surgeon qualifications prior to consideration for a surgeon position was highly desired. Residency training within Family Medicine or Emergency Medicine constituted the vast majority of specialty preference. Understanding which characteristics and attributes are desirable to current surgeons and commanders can aid physicians interested in SOF surgeon positions. Using this study and future studies can guide career planning and foster the selection of ideally trained physicians who will operate at the tip of the spear. The views expressed are those of the author(s) and do not reflect the official policy of the Department of the Army, the Department of Defense or the U.S. Government. 2012.

Global characteristics of auroral Hall currents derived from the Swarm constellation: dependences on season and IMF orientation

NASA Astrophysics Data System (ADS)

Huang, Tao; Lühr, Hermann; Wang, Hui

2017-11-01

On the basis of field-aligned currents (FACs) and Hall currents derived from high-resolution magnetic field data of the Swarm constellation, the average characteristics of these two current systems in the auroral regions are comprehensively investigated by statistical methods. This is the first study considering both current types determined simultaneously by the same spacecraft in both hemispheres. The FAC distribution, derived from the novel Swarm dual-spacecraft approach, reveals the well-known features of Region 1 (R1) and Region 2 (R2) FACs. At high latitudes, Region 0 (R0) FACs appear on the dayside. Their flow direction, up or down, depends on the orientation of the interplanetary magnetic field (IMF) By component. Of particular interest is the distribution of auroral Hall currents. The prominent auroral electrojets are found to be closely controlled by the solar wind input, but we find no dependence of their intensity on the IMF By orientation. The eastward electrojet is about 1.5 times stronger in local summer than in winter. Conversely, the westward electrojet shows less dependence on season. As to higher latitudes, part of the electrojet current is closed over the polar cap. Here the seasonal variation of conductivity mainly controls the current density. During local summer of the Northern Hemisphere, there is a clear channeling of return currents over the polar cap. For positive (negative) IMF By a dominant eastward (westward) Hall current circuit is formed from the afternoon (morning) electrojet towards the dawn side (dusk side) polar cap return current. The direction of polar cap Hall currents in the noon sector depends directly on the orientation of the IMF By. This is true for both signs of the IMF Bz component. Comparable Hall current distributions can be observed in the Southern Hemisphere but for opposite IMF By signs. Around the midnight sector the westward substorm electrojet is dominating. As expected, it is highly dependent on magnetic activity, but it shows only little response to season and IMF By polarity. An important finding is that all the IMF By dependences of FACs and Hall currents practically disappear in the dark winter hemisphere.

Contribution of the backstreaming ions to the Self-Magnetic pinch (SMP) diode current

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mazarakis, Michael G.; Cuneo, Michael E.; Fournier, Sean D.

2016-08-08

Summary form only given. The results presented here were obtained with an SMP diode mounted at the front high voltage end of the RITS accelerator. RITS is a Self-Magnetically Insulated Transmission Line (MITL) voltage adder that adds the voltage pulses of six 1.3 MV inductively insulated cavities. Our experiments had two objectives: first to measure the contribution of the back-streaming ion currents emitted from the anode target to the diode beam current, and second to try to evaluate the energy of those ions and hence the actual Anode-Cathode (A-K) gap actual voltage. In any very high voltage inductive voltage addermore » (IVA) utilizing MITLs to transmit the power to the diode load, the precise knowledge of the accelerating voltage applied on the anode-cathode (A-K) gap is problematic. The accelerating voltage quoted in the literature is from estimates based on measurements of the anode and cathode currents of the MITL far upstream from the diode and utilizing the para-potential flow theories and inductive corrections. Thus it would be interesting to have another independent measurement to evaluate the A-K voltage. The diode's anode is made of a number of high Z metals in order to produce copious and energetic flash x-rays. The backstreaming currents are a strong fraction of the anode materials and their stage of cleanness and gas adsorption. We have measured the back-streaming ion currents emitted from the anode and propagating through a hollow cathode tip for various diode configurations and different techniques of target cleaning treatments, such as heating to very high temperatures with DC and pulsed current, with RF plasma cleaning and with both plasma cleaning and heating. Finally, we have also evaluated the A-K gap voltage by ion filtering techniques.« less

Measuring the Interestingness of Articles in a Limited User Environment Prospectus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pon, Raymond K.

2007-04-18

Search engines, such as Google, assign scores to news articles based on their relevancy to a query. However, not all relevant articles for the query may be interesting to a user. For example, if the article is old or yields little new information, the article would be uninteresting. Relevancy scores do not take into account what makes an article interesting, which would vary from user to user. Although methods such as collaborative filtering have been shown to be effective in recommendation systems, in a limited user environment there are not enough users that would make collaborative filtering effective. I presentmore » a general framework for defining and measuring the ''interestingness'' of articles, called iScore, incorporating user-feedback including tracking multiple topics of interest as well as finding interesting entities or phrases in a complex relationship network. I propose and have shown the validity of the following: 1. Filtering based on only topic relevancy is insufficient for identifying interesting articles. 2. No single feature can characterize the interestingness of an article for a user. It is the combination of multiple features that yields higher quality results. For each user, these features have different degrees of usefulness for predicting interestingness. 3. Through user-feedback, a classifier can combine features to predict interestingness for the user. 4. Current evaluation corpora, such as TREC, do not capture all aspects of personalized news filtering systems necessary for system evaluation. 5. Focusing on only specific evolving user interests instead of all topics allows for more efficient resource utilization while yielding high quality recommendation results. 6. Multiple profile vectors yield significantly better results than traditional methods, such as the Rocchio algorithm, for identifying interesting articles. Additionally, the addition of tracking multiple topics as a new feature in iScore, can improve iScore's classification performance. 7. Multiple topic tracking yields better results than the best results from the last TREC adaptive filtering run. As future work, I will address the following hypothesis: Entities and the relationship among these entities using current information extraction technology can be utilized to identify entities of interest and relationships of interest, using a scheme such as PageRank. And I will address one of the following two hypotheses: 1. By addressing the multiple reading roles that a single user may have, classification results can be improved. 2. By tailoring the operating parameters of MTT, better classification results can be achieved.« less

Simulations towards the achievement of non-inductive current ramp-up and sustainment in the National Spherical Torus Experiment Upgrade

DOE PAGES

Poli, F. M.; Andre, R. G.; Bertelli, N.; ...

2015-10-30

One of the goals of the National Spherical Torus Experiment Upgrade (NSTX-U) (Menard et al 2012 Nucl. Fusion 52 083015) is the demonstration of fully non-inductive start-up, current ramp-up and sustainment. This work discusses predictive simulations where the available heating and current drive systems are combined to maximize the non-inductive current and minimize the solenoidal contribution. Radio-frequency waves at harmonics higher than the ion cyclotron resonance (high-harmonic fast waves (HHFW)) and neutral beam injection are used to ramp the plasma current non-inductively starting from an initial Ohmic plasma. An interesting synergy is observed in the simulations between the HHFW andmore » electron cyclotron (EC) wave heating. Furthermore, time-dependent simulations indicate that, depending on the phasing of the HHFW antenna, EC wave heating can significantly increase the effectiveness of the radio-frequency power, by heating the electrons and increasing the current drive efficiency, thus relaxing the requirements on the level of HHFW power that needs to be absorbed in the core plasma to drive the same amount of fast-wave current.« less

Spin Funneling for Enhanced Spin Injection into Ferromagnets

PubMed Central

Sayed, Shehrin; Diep, Vinh Q.; Camsari, Kerem Yunus; Datta, Supriyo

2016-01-01

It is well-established that high spin-orbit coupling (SOC) materials convert a charge current density into a spin current density which can be used to switch a magnet efficiently and there is increasing interest in identifying materials with large spin Hall angle for lower switching current. Using experimentally benchmarked models, we show that composite structures can be designed using existing spin Hall materials such that the effective spin Hall angle is larger by an order of magnitude. The basic idea is to funnel spins from a large area of spin Hall material into a small area of ferromagnet using a normal metal with large spin diffusion length and low resistivity like Cu or Al. We show that this approach is increasingly effective as magnets get smaller. We avoid unwanted charge current shunting by the low resistive NM layer utilizing the newly discovered phenomenon of pure spin conduction in ferromagnetic insulators via magnon diffusion. We provide a spin circuit model for magnon diffusion in FMI that is benchmarked against recent experiments and theory. PMID:27374496

Spin Funneling for Enhanced Spin Injection into Ferromagnets

NASA Astrophysics Data System (ADS)

Sayed, Shehrin; Diep, Vinh Q.; Camsari, Kerem Yunus; Datta, Supriyo

2016-07-01

It is well-established that high spin-orbit coupling (SOC) materials convert a charge current density into a spin current density which can be used to switch a magnet efficiently and there is increasing interest in identifying materials with large spin Hall angle for lower switching current. Using experimentally benchmarked models, we show that composite structures can be designed using existing spin Hall materials such that the effective spin Hall angle is larger by an order of magnitude. The basic idea is to funnel spins from a large area of spin Hall material into a small area of ferromagnet using a normal metal with large spin diffusion length and low resistivity like Cu or Al. We show that this approach is increasingly effective as magnets get smaller. We avoid unwanted charge current shunting by the low resistive NM layer utilizing the newly discovered phenomenon of pure spin conduction in ferromagnetic insulators via magnon diffusion. We provide a spin circuit model for magnon diffusion in FMI that is benchmarked against recent experiments and theory.

Notch-Boosted Domain Wall Propagation in Magnetic Nanowires

NASA Astrophysics Data System (ADS)

Wang, Xiang Rong; Yuan, Hauiyang

Magnetic domain wall (DW) motion along a nanowire underpins many proposals of spintronic devices. High DW propagation velocity is obviously important because it determines the device speed. Thus it is interesting to search for effective control knobs of DW dynamics. We report a counter-intuitive finding that notches in an otherwise homogeneous magnetic nanowire can boost current-induced domain wall (DW) propagation. DW motion in notch-modulated wires can be classified into three phases: 1) A DW is pinned around a notch when the current density is below the depinning current density. 2) DW propagation velocity above the depinning current density is boosted by notches when non-adiabatic spin-transfer torque strength is smaller than the Gilbert damping constant. The boost can be many-fold. 3) DW propagation velocity is hindered when non-adiabatic spin-transfer torque strength is larger than the Gilbert damping constant. This work was supported by Hong Kong GRF Grants (Nos. 163011151 and 605413) and the Grant from NNSF of China (No. 11374249).

High efficiency thermionic converter studies

NASA Technical Reports Server (NTRS)

Huffman, F. N.; Sommer, A. H.; Balestra, C. L.; Briere, D. P.; Oettinger, P. E.

1976-01-01

The objective is to improve thermionic converter performance by means of reduced interelectrode losses, greater emitter capabilities, and lower collector work functions until the converter performance level is suitable for out-of-core space reactors and radioisotope generators. Electrode screening experiments have identified several promising collector materials. Back emission work function measurements of a ZnO collector in a thermionic diode have given values less than 1.3 eV. Diode tests were conducted over the range of temperatures of interest for space power applications. Enhanced mode converter experiments have included triodes operated in both the surface ionization and plasmatron modes. Pulsed triodes were studied as a function of pulse length, pulse potential, inert gas fill pressure, cesium pressure, spacing, emitter temperature and collector temperature. Current amplifications (i.e., mean output current/mean grid current) of several hundred were observed up to output current densities of one amp/sq cm. These data correspond to an equivalent arc drop less than 0.1 eV.

Stand alone, low current measurements on possible sensing platforms via Arduino Uno microcontroller with modified commercially available sensors

NASA Astrophysics Data System (ADS)

Tanner, Meghan; Henson, Gabriel; Senevirathne, Indrajith

Advent of cost-effective solid-state sensors has spurred an immense interest in microcontrollers, in particular Arduino microcontrollers. These include serious engineering and physical science applications due to their versatility and robustness. An Arduino microcontroller coupled with a commercially available sensor has been used to methodically measure, record, and explore low currents, low voltages, and corresponding dissipated power towards assessing secondary physical properties in a select set of engineered systems. System was assembled via breadboard, wire, and simple soldering with an Arduino Uno with ATmega328P microcontroller connected to a PC. The microcontroller was programmed with Arduino software while the bootloader was used to upload the code. High-side measurement INA169 current shunt monitor was used to measure corresponding low to ultra-low currents and voltages. A collection of measurements was obtained via the sensor and was compared with measurements from standardized devices to assess reliability and uncertainty. Some sensors were modified/hacked to improve the sensitivity of the measurements.

Studies in High Current Density Ion Sources for Heavy Ion Fusion Applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chacon-Golcher, Edwin

This dissertation develops diverse research on small (diameter ~ few mm), high current density (J ~ several tens of mA/cm 2) heavy ion sources. The research has been developed in the context of a programmatic interest within the Heavy Ion Fusion (HIF) Program to explore alternative architectures in the beam injection systems that use the merging of small, bright beams. An ion gun was designed and built for these experiments. Results of average current density yield () at different operating conditions are presented for K + and Cs + contact ionization sources and potassium aluminum silicate sources. Maximum valuesmore » for a K + beam of ~90 mA/cm 2 were observed in 2.3 μs pulses. Measurements of beam intensity profiles and emittances are included. Measurements of neutral particle desorption are presented at different operating conditions which lead to a better understanding of the underlying atomic diffusion processes that determine the lifetime of the emitter. Estimates of diffusion times consistent with measurements are presented, as well as estimates of maximum repetition rates achievable. Diverse studies performed on the composition and preparation of alkali aluminosilicate ion sources are also presented. In addition, this work includes preliminary work carried out exploring the viability of an argon plasma ion source and a bismuth metal vapor vacuum arc (MEVVA) ion source. For the former ion source, fast rise-times (~ 1 μs), high current densities (~ 100 mA/cm +) and low operating pressures (< 2 mtorr) were verified. For the latter, high but acceptable levels of beam emittance were measured (ε n ≤ 0.006 π· mm · mrad) although measured currents differed from the desired ones (I ~ 5mA) by about a factor of 10.« less

High-throughput method for the quantitation of metabolites and co-factors from homocysteine-methionine cycle for nutritional status assessment.

PubMed

Da Silva, Laeticia; Collino, Sebastiano; Cominetti, Ornella; Martin, Francois-Pierre; Montoliu, Ivan; Moreno, Sergio Oller; Corthesy, John; Kaput, Jim; Kussmann, Martin; Monteiro, Jacqueline Pontes; Guiraud, Seu Ping

2016-09-01

There is increasing interest in the profiling and quantitation of methionine pathway metabolites for health management research. Currently, several analytical approaches are required to cover metabolites and co-factors. We report the development and the validation of a method for the simultaneous detection and quantitation of 13 metabolites in red blood cells. The method, validated in a cohort of healthy human volunteers, shows a high level of accuracy and reproducibility. This high-throughput protocol provides a robust coverage of central metabolites and co-factors in one single analysis and in a high-throughput fashion. In large-scale clinical settings, the use of such an approach will significantly advance the field of nutritional research in health and disease.

7 CFR 1951.223 - Reamortization.

Code of Federal Regulations, 2012 CFR

2012-01-01

... adjusted to no less than the poverty interest rate and the term of the loans may be extended up to a new 40... delinquent amount. Accrued interest will be at the rate currently reflected in Finance Office records. (1...; and (E) The interest rate. (iii) A payment will be due on the next scheduled due date. Deferment of...

7 CFR 1951.223 - Reamortization.

Code of Federal Regulations, 2011 CFR

2011-01-01

... adjusted to no less than the poverty interest rate and the term of the loans may be extended up to a new 40... delinquent amount. Accrued interest will be at the rate currently reflected in Finance Office records. (1...; and (E) The interest rate. (iii) A payment will be due on the next scheduled due date. Deferment of...

7 CFR 1951.223 - Reamortization.

Code of Federal Regulations, 2013 CFR

2013-01-01

... adjusted to no less than the poverty interest rate and the term of the loans may be extended up to a new 40... delinquent amount. Accrued interest will be at the rate currently reflected in Finance Office records. (1...; and (E) The interest rate. (iii) A payment will be due on the next scheduled due date. Deferment of...

7 CFR 1951.223 - Reamortization.

Code of Federal Regulations, 2014 CFR

2014-01-01

... adjusted to no less than the poverty interest rate and the term of the loans may be extended up to a new 40... delinquent amount. Accrued interest will be at the rate currently reflected in Finance Office records. (1...; and (E) The interest rate. (iii) A payment will be due on the next scheduled due date. Deferment of...

The HEXACO and Five-Factor Models of Personality in Relation to RIASEC Vocational Interests

ERIC Educational Resources Information Center

McKay, Derek A.; Tokar, David M.

2012-01-01

The current study extended the empirical research on the overlap of vocational interests and personality by (a) testing hypothesized relations between RIASEC interests and the personality dimensions of the HEXACO model, and (b) exploring the HEXACO personality model's predictive advantage over the five-factor model (FFM) in capturing RIASEC…

5 CFR 842.605 - Election of insurable interest rate.

Code of Federal Regulations, 2013 CFR

2013-01-01

... rate who was the current spouse at both the time of the retiree's retirement and death may, within 2... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Election of insurable interest rate. 842... Election of insurable interest rate. (a) At the time of retirement, an employee or Member in good health...

5 CFR 842.605 - Election of insurable interest rate.

Code of Federal Regulations, 2014 CFR

2014-01-01

... rate who was the current spouse at both the time of the retiree's retirement and death may, within 2... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Election of insurable interest rate. 842... Election of insurable interest rate. (a) At the time of retirement, an employee or Member in good health...

Analysis of Readability and Interest of Marketing Education Textbooks: Implications for Special Needs Learners.

ERIC Educational Resources Information Center

Jones, Karen H.; And Others

1993-01-01

The readability, reading ease, interest level, and writing style of 20 current textbooks in secondary marketing education were evaluated. Readability formulas consistently identified lower reading levels for special needs education, human interest scores were not very reliable information sources, and writing style was also a weak variable. (JOW)

Caffeine, HPLC, Outreach (How Can We Interest Kids in Science?)

USDA-ARS?s Scientific Manuscript database

A current challenge for the scientific community is to generate an interest in science in the general public. If we can interest our youth in science we can produce more scientists and raise awareness of science in our society. An outreach activity will be described which can be brought into the cl...

International variations in application of the best-interest standard across the age spectrum.

PubMed

Laventhal, N; Verhagen, A A E; Hansen, T W R; Dempsey, E; Davis, P G; Musante, G A; Wiles, A; Meadow, W; Janvier, A

2017-02-01

Ethically and legally, assertions that resuscitation is in a patient's best interest should be inversely correlated with willingness to forego intensive care (and accept comfort care) at the surrogate's request. Previous single country studies have demonstrated a relative devaluation of neonates when compared with other critically ill patients. In this international study, physicians in Argentina, Australia, Canada, Ireland, The Netherlands, Norway and the United States were presented with eight hypothetical vignettes of incompetent critically ill patients of different ages. They were asked to make assessments about best interest, respect for surrogate autonomy and to rank the patients in a triage scenario. In total, 2237 physicians responded (average response rate 61%). In all countries and scenarios, participants did not accept to withhold resuscitation if they estimated it was in the patient's best interest, except for scenarios involving neonates. Young children (other than neonates) were given high priority for resuscitation, regardless of existing disability. For neonates, surrogate autonomy outweighed assessment of best interest. In all countries, a 2-month-old-infant with meningitis and a multiply disabled 7-year old were resuscitated first in the triage scenario, with more variable ranking of the two neonates, which were ranked below patients with considerably worse prognosis. The value placed on the life of newborns is less than that expected according to predicted clinical outcomes and current legal and ethical theory relative to best interests. Value assessments on the basis of age, disability and prognosis appear to transcend culture, politics and religion in this domain.

Incorporation of a Global Surgery Rotation into an Academic General Surgery Residency Program: Impact and Perceptions.

PubMed

LeCompte, Michael Thomas; Goldman, Connor; Tarpley, John L; Tarpley, Margaret; Hansen, Erik N; Nthumba, Peter M; Terhune, Kyla P; Kauffmann, Rondi M

2018-03-14

Global surgery is increasingly recognized as a vital component of international public health. Access to basic surgical care is limited in much of the world, resulting in a global burden of treatable disease. To address the lack of surgical workforce in underserved environments and to foster ongoing interest in global health among US-trained surgeons, our institution established a residency rotation through partnership with an academic hospital in Kijabe, Kenya. This study evaluates the perceptions of residents involved in the rotation, as well as its impact on their future involvement in global health. A retrospective review of admission applications from residents matriculating at our institution was conducted to determine stated interest in global surgery. These were compared to post-rotation evaluations and follow-up surveys to assess interest in global surgery and the effects of the rotation on the practices of the participants. A total of 78 residents matriculated from 2006 to 2016. Seventeen participated in the rotation with 76% of these reporting high satisfaction with the rotation. Sixty-five percent had no prior experience providing health care in an international setting. Post-rotation surveys revealed an increase in global surgery interest among participants. Long-term interest was demonstrated in 33% (n = 6) who reported ongoing activity in global health in their current practices. Participation in global rotations was also associated with increased interest in domestically underserved populations and affected economic and cost decisions within graduates' practices.

Mind wandering during film comprehension: The role of prior knowledge and situational interest.

PubMed

Kopp, Kristopher; Mills, Caitlin; D'Mello, Sidney

2016-06-01

This study assessed the occurrence and factors that influence mind wandering (MW) in the domain of film comprehension. The cascading model of inattention assumes that a stronger mental representation (i.e., a situation model) during comprehension results in less MW. Accordingly, a suppression hypothesis suggests that MW would decrease as a function of having the knowledge of the plot of a film prior to viewing, because the prior-knowledge would help to strengthen the situation model during comprehension. Furthermore, an interest-moderation hypothesis would predict that the suppression effect of prior-knowledge would only emerge when there was interest in viewing the film. In the current experiment, 108 participants either read a short story that depicted the plot (i.e., prior-knowledge condition) or read an unrelated story of equal length (control condition) prior to viewing the short film (32.5 minutes) entitled The Red Balloon. Participants self-reported their interest in viewing the film immediately before the film was presented. MW was tracked using a self-report method targeting instances of MW with metacognitive awareness. Participants in the prior-knowledge condition reported less MW compared with the control condition, thereby supporting the suppression hypothesis. MW also decreased over the duration of the film, but only for those with prior-knowledge of the film. Finally, prior-knowledge effects on MW were only observed when interest was average or high, but not when interest was low.

Predicting tidal currents in San Francisco Bay using a spectral model

USGS Publications Warehouse

Burau, Jon R.; Cheng, Ralph T.

1988-01-01

This paper describes the formulation of a spectral (or frequency based) model which solves the linearized shallow water equations. To account for highly variable basin bathymetry, spectral solutions are obtained using the finite element method which allows the strategic placement of the computation points in the specific areas of interest or in areas where the gradients of the dependent variables are expected to be large. Model results are compared with data using simple statistics to judge overall model performance in the San Francisco Bay estuary. Once the model is calibrated and verified, prediction of the tides and tidal currents in San Francisco Bay is accomplished by applying astronomical tides (harmonic constants deduced from field data) at the prediction time along the model boundaries.

What Pinnipeds Have to Say about Human Speech, Music, and the Evolution of Rhythm.

PubMed

Ravignani, Andrea; Fitch, W Tecumseh; Hanke, Frederike D; Heinrich, Tamara; Hurgitsch, Bettina; Kotz, Sonja A; Scharff, Constance; Stoeger, Angela S; de Boer, Bart

2016-01-01

Research on the evolution of human speech and music benefits from hypotheses and data generated in a number of disciplines. The purpose of this article is to illustrate the high relevance of pinniped research for the study of speech, musical rhythm, and their origins, bridging and complementing current research on primates and birds. We briefly discuss speech, vocal learning, and rhythm from an evolutionary and comparative perspective. We review the current state of the art on pinniped communication and behavior relevant to the evolution of human speech and music, showing interesting parallels to hypotheses on rhythmic behavior in early hominids. We suggest future research directions in terms of species to test and empirical data needed.

Why the Lack of Academic Literature on Export Controls?

NASA Technical Reports Server (NTRS)

Kremic, Tibor

2001-01-01

Export controls is currently a relevant and dynamic topic. Given the growth of global operations and the high-tech nature of many products, an increase in awareness and understanding of the impacts of export controls are necessary. A structured approach to export controls has been in existence since 1949. Despite over 50 years of history, surprisingly little academic research and literature exists on the topic. This paper explores the current export control environment and explores possible reasons for the limited academic interest. Five possible reasons are discussed: (1) dynamic nature of the topic; (2) difficulty in ensuring accurate data; (3) Complexity of the problem; (4) relatively small economic impact; and (5) sensitive information. A research approach is recommended that considers these potential obstacles.

Targeting the Cerebellum by Noninvasive Neurostimulation: a Review.

PubMed

van Dun, Kim; Bodranghien, Florian; Manto, Mario; Mariën, Peter

2017-06-01

Transcranial magnetic and electric stimulation of the brain are novel and highly promising techniques currently employed in both research and clinical practice. Improving or rehabilitating brain functions by modulating excitability with these noninvasive tools is an exciting new area in neuroscience. Since the cerebellum is closely connected with the cerebral regions subserving motor, associative, and affective functions, the cerebello-thalamo-cortical pathways are an interesting target for these new techniques. Targeting the cerebellum represents a novel way to modulate the excitability of remote cortical regions and their functions. This review brings together the studies that have applied cerebellar stimulation, magnetic and electric, and presents an overview of the current knowledge and unsolved issues. Some recommendations for future research are implemented as well.

Advances in the surgical management of prolapse.

PubMed

Slack, Alex; Jackson, Simon

2007-03-01

Prolapse is an extremely common condition, for which 11% of women will have a surgical procedure at some point in their lives. The recurrence rate after most of the traditional surgical procedures is high and upto 29% of women who have had surgery for prolapse will require a further operation. In order to improve the surgical outcome, there is currently much interest in the use of grafts to augment traditional repairs and new procedures have been developed using specifically developed grafts. These have been combined with minimally invasive surgical techniques in an attempt to reduce surgical morbidity. These procedures may improve the outcome of surgery for prolapse. However, there is currently a lack of long-term data from randomized trials to demonstrate their effectiveness and safety.

Corporate Social Responsibility in Aviation

NASA Technical Reports Server (NTRS)

Phillips, Edwin D.

2006-01-01

The dialog within aviation management education regarding ethics is incomplete without a discussion of corporate social responsibility (CSR). CSR research requires discussion involving: (a) the current emphasis on CSR in business in general and aviation specifically; (b) business and educational theory that provide a basis for aviation companies to engage in socially responsible actions; (c) techniques used by aviation and aerospace companies to fulfill this responsibility; and (d) a glimpse of teaching approaches used in university aviation management classes. The summary of this research suggests educators explain CSR theory and practice to students in industry and collegiate aviation management programs. Doing so extends the discussion of ethical behavior and matches the current high level of interest and activity within the aviation industry toward CSR.

Magnetic vortex excitation as spin torque oscillator and its unusual trajectories

NASA Astrophysics Data System (ADS)

Natarajan, Kanimozhi; Muthuraj, Ponsudana; Rajamani, Amuda; Arumugam, Brinda

2018-05-01

We report an interesting observation of unusual trajectories of vortex core oscillations in a spin valve pillar. Micromagnetic simulation in the composite free layer spin valve nano-pillar shows magnetic vortex excitation under critical current density. When current density is slightly increased and wave vector is properly tuned, for the first time we observe a star like and square gyration. Surprisingly this star like and square gyration also leads to steady, coherent and sustained oscillations. Moreover, the frequency of gyration is also very high for this unusual trajectories. The power spectral analysis reveals that there is a marked increase in output power and frequency with less distortions. Our investigation explores the possibility of these unusual trajectories to exhibit spin torque oscillations.

What Pinnipeds Have to Say about Human Speech, Music, and the Evolution of Rhythm

PubMed Central

Ravignani, Andrea; Fitch, W. Tecumseh; Hanke, Frederike D.; Heinrich, Tamara; Hurgitsch, Bettina; Kotz, Sonja A.; Scharff, Constance; Stoeger, Angela S.; de Boer, Bart

2016-01-01

Research on the evolution of human speech and music benefits from hypotheses and data generated in a number of disciplines. The purpose of this article is to illustrate the high relevance of pinniped research for the study of speech, musical rhythm, and their origins, bridging and complementing current research on primates and birds. We briefly discuss speech, vocal learning, and rhythm from an evolutionary and comparative perspective. We review the current state of the art on pinniped communication and behavior relevant to the evolution of human speech and music, showing interesting parallels to hypotheses on rhythmic behavior in early hominids. We suggest future research directions in terms of species to test and empirical data needed. PMID:27378843

Investigation of the Static and Dynamic Characteristics for a Wafer-Fused C-band VCSEL in the Mode of the Optical-Electric Converter

NASA Astrophysics Data System (ADS)

Belkin, M. E.

2018-01-01

The results of an experimental study for a long wavelength vertical cavity surface-emitting laser of a wafer-fused construction as an effective resonant cavity enhanced photodetector of analog optical signals are described. The device is of interest for a number of promising microwave photonics applications and for creation of a low-cost photoreceiver in a high-speed fiber optics telecommunication system with dense wavelength division multiplexing. The schematic of the testbed, the original technique allowing to calculate the passband of the built-in optical cavity, and the results of measuring dark current, current responsivity, amplitude- and phase-frequency characteristics during the process of photo-detection are demonstrated.

The MAJORANA DEMONSTRATOR for 0νββ: Current Status and Future Plans

NASA Astrophysics Data System (ADS)

Green, M. P.; Abgrall, N.; Aguayo, E.; Avignone, F. T.; Barabash, A. S.; Bertrand, F. E.; Boswell, M.; Brudanin, V.; Busch, M.; Byram, D.; Caldwell, A. S.; Chan, Y.-D.; Christofferson, C. D.; Combs, D. C.; Cuesta, C.; Detwiler, J. A.; Doe, P. J.; Efremenko, Yu.; Egorov, V.; Ejiri, H.; Elliott, S. R.; Fast, J. E.; Finnerty, P.; Fraenkle, F. M.; Galindo-Uribarri, A.; Giovanetti, G. K.; Goett, J.; Gruszko, J.; Guiseppe, V. E.; Gusev, K.; Hallin, A. L.; Hazama, R.; Hegai, A.; Henning, R.; Hoppe, E. W.; Howard, S.; Howe, M. A.; Keeter, K. J.; Kidd, M. F.; Kochetov, O.; Konovalov, S. I.; Kouzes, R. T.; LaFerriere, B. D.; Leon, J.; Leviner, L. E.; Loach, J. C.; MacMullin, J.; MacMullin, S.; Martin, R. D.; Meijer, S.; Mertens, S.; Nomachi, M.; Orrell, J. L.; O'Shaughnessy, C.; Overman, N. R.; Phillips, D. G.; Poon, A. W. P.; Pushkin, K.; Radford, D. C.; Rager, J.; Rielage, K.; Robertson, R. G. H.; Romero-Romero, E.; Ronquest, M. C.; Schubert, A. G.; Shanks, B.; Shima, T.; Shirchenko, M.; Snavely, K. J.; Snyder, N.; Suriano, A. M.; Thompson, J.; Timkin, V.; Tornow, W.; Trimble, J. E.; Varner, R. L.; Vasilyev, S.; Vetter, K.; Vorren, K.; White, B. R.; Wilkerson, J. F.; Wiseman, C.; Xu, W.; Yakushev, E.; Young, A. R.; Yu, C.-H.; Yumatov, V.

The MAJORANA DEMONSTRATOR will search for neutrinoless-double-beta decay (0νββ) in 76Ge, while establishing the feasibility of a future tonne-scale germanium-based 0νββ experiment, and performing searches for new physics beyond the Standard Model. The experiment, currently under construction at the Sanford Underground Research Facility in Lead, SD, will consist of a pair of modular high-purity germanium detector arrays housed inside of a compact copper, lead, and polyethylene shield. Through a combination of strict materials qualifications and assay, low-background design, and powerful background rejection techniques, the Demonstrator aims to achieve a background rate in the 0νββ region of interest (ROI) of no more than 3 counts in the 0νββ-decay ROI per tonne of target isotope per year (cnts/(ROI-t-y)). The current status of the Demonstrator is discussed, as are plans for its completion.

Negative differential resistance in low Al-composition p-GaN/Mg-doped Al0.15Ga0.85N/n+-GaN hetero-junction grown by metal-organic chemical vapor deposition on sapphire substrate

NASA Astrophysics Data System (ADS)

Zhang, Kexiong; Liang, Hongwei; Shen, Rensheng; Wang, Dongsheng; Tao, Pengcheng; Liu, Yang; Xia, Xiaochuan; Luo, Yingmin; Du, Guotong

2014-02-01

Negative differential resistance (NDR) behavior was observed in low Al-composition p-GaN/Mg-doped-Al0.15Ga0.85N/n+-GaN hetero-junction grown by metal-organic chemical vapor deposition on sapphire substrate. The energy band and free carrier concentration of hetero-junction were studied by the model of the self-consistent solution of Schrödinger-Poisson equations combined with polarization engineering theory. At the forward bias of 0.95 V, the NDR effect has a high peak-to-valley current ratio of ˜9 with a peak current of 22.4 mA (˜current density of 11.4 A/cm2). An interesting phenomenon of NDR disappearance after consecutive scans and recurrence after electrical treatment was observed, which was associated with Poole-Frenkel effect.

Ultra-low current beams in UMER to model space-charge effects in high-energy proton and ion machines

NASA Astrophysics Data System (ADS)

Bernal, S.; Beaudoin, B.; Baumgartner, H.; Ehrenstein, S.; Haber, I.; Koeth, T.; Montgomery, E.; Ruisard, K.; Sutter, D.; Yun, D.; Kishek, R. A.

2017-03-01

The University of Maryland Electron Ring (UMER) has operated traditionally in the regime of strong space-charge dominated beam transport, but small-current beams are desirable to significantly reduce the direct (incoherent) space-charge tune shift as well as the tune depression. This regime is of interest to model space-charge effects in large proton and ion rings similar to those used in nuclear physics and spallation neutron sources, and also for nonlinear dynamics studies of lattices inspired on the Integrable Optics Test Accelerator (IOTA). We review the definitions of beam vs. space-charge intensities and discuss three methods for producing very small beam currents in UMER. We aim at generating 60µA - 1.0mA, 100 ns, 10 keV beams with normalized rms emittances of the order of 0.1 - 1.0µm.

Artificial intelligence in the materials processing laboratory

NASA Technical Reports Server (NTRS)

Workman, Gary L.; Kaukler, William F.

1990-01-01

Materials science and engineering provides a vast arena for applications of artificial intelligence. Advanced materials research is an area in which challenging requirements confront the researcher, from the drawing board through production and into service. Advanced techniques results in the development of new materials for specialized applications. Hand-in-hand with these new materials are also requirements for state-of-the-art inspection methods to determine the integrity or fitness for service of structures fabricated from these materials. Two problems of current interest to the Materials Processing Laboratory at UAH are an expert system to assist in eddy current inspection of graphite epoxy components for aerospace and an expert system to assist in the design of superalloys for high temperature applications. Each project requires a different approach to reach the defined goals. Results to date are described for the eddy current analysis, but only the original concepts and approaches considered are given for the expert system to design superalloys.

The Majorana Demonstrator for 0νββ: Current Status and Future Plans

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green, Matthew P.; Avignone, F. T.; Bertrand, Jr, Fred E

2015-01-01

The Majorana Demonstrator will search for neutrinoless-double-beta decay (0νββ) in 76Ge, while establishing the feasibility of a future tonne-scale germanium-based 0νββ experiment, and performing searches for new physics beyond the Standard Model. The experiment, currently under construction at the Sanford Underground Research Facility in Lead, SD, will consist of a pair of modular high-purity germanium detector arrays housed inside of a compact copper, lead, and polyethylene shield. Through a combination of strict materials qualifications and assay, low-background design, and powerful background rejection techniques, the Demonstrator aims to achieve a background rate in the 0νββ region of interest (ROI) of nomore » more than 3cnts/(ROI-t-y). The current status of the Demonstrator is discussed, as are plans for its completion.« less

Evaluating interest in an influenza A(H5N1) vaccine among laboratory workers who work with highly-pathogenic avian influenza viruses in the United States.

PubMed

Russell, Kate E; Bresee, J S; Katz, J M; Olsen, S J

2018-01-04

Highly pathogenic avian influenza A (HPAI) viruses found in poultry and wild birds occasionally infect humans and can cause serious disease. In 2014, the Advisory Committee on Immunization Practices (ACIP) reviewed data from one licensed ASO3-adjuvanted influenza A(H5N1) vaccine for consideration of use during inter-pandemic periods among persons with occupational exposure. To guide vaccine policy decisions, we conducted a survey of laboratory workers to assess demand for HPAI vaccination. We designed an anonymous web survey (EpiInfo 7.0) to collect information on demographics, type of work and time spent with HPAI viruses, and interest in HPAI vaccination. Eligible participants were identified from 42 entities registered with United States Department of Agriculture's Agricultural Select Agent program in 2016 and emailed electronic surveys. Personnel with Biosafety Level 3 enhanced (BSL-3E) laboratory access were surveyed. Descriptive analysis was performed. Overall, 131 responses were received from 33 principal investigators, 26 research scientists, 24 technicians, 15 postdoctoral fellows, 6 students, and 27 others. The estimated response rate was 15% among the laboratory personnel of responding principal investigators. One hundred respondents reported working in a BSL-3E area where HPAI experiments occurred with a mean time of 5.1-11.7 h per week. Overall, 49% were interested in receiving an A(H5N1) vaccine. By role, interest was highest among students (80%) and among those who spent >50% of their time in a BSL-3E area (64%). Most (61%) of those who said they might be or were not interested in vaccine believed it would not provide additional protection to current safety practices. Half of responding laboratory workers was interested in receiving an influenza A(H5N1) vaccine. HPAI vaccination of laboratory workers at risk of occupational exposure could be used along with existing safety practices to protect this population. Published by Elsevier Ltd.

The Interplay between Scientific Overlap and Cooperation and the Resulting Gain in Co-Authorship Interactions.

PubMed

Mayrose, Itay; Freilich, Shiri

2015-01-01

Considering the importance of scientific interactions, understanding the principles that govern fruitful scientific research is crucial to policy makers and scientists alike. The outcome of an interaction is to a large extent dependent on the balancing of contradicting motivations accompanying the establishment of collaborations. Here, we assembled a dataset of nearly 20,000 publications authored by researchers affiliated with ten top universities. Based on this data collection, we estimated the extent of different interaction types between pairwise combinations of researchers. We explored the interplay between the overlap in scientific interests and the tendency to collaborate, and associated these estimates with measures of scientific quality and social accessibility aiming at studying the typical resulting gain of different interaction patterns. Our results show that scientists tend to collaborate more often with colleagues with whom they share moderate to high levels of mutual interests and knowledge while cooperative tendency declines at higher levels of research-interest overlap, suggesting fierce competition, and at the lower levels, suggesting communication gaps. Whereas the relative number of alliances dramatically differs across a gradient of research overlap, the scientific impact of the resulting articles remains similar. When considering social accessibility, we find that though collaborations between remote researchers are relatively rare, their quality is significantly higher than studies produced by close-circle scientists. Since current collaboration patterns do not necessarily overlap with gaining optimal scientific quality, these findings should encourage scientists to reconsider current collaboration strategies.

Preparing Historically Underserved Students for STEM Careers: The Role of an Inquiry-based High School Science Sequence Beginning with Physics

NASA Astrophysics Data System (ADS)

Bridges, Jon P.

Improving the STEM readiness of students from historically underserved groups is a moral and economic imperative requiring greater attention and effort than has been shown to date. The current literature suggests a high school science sequence beginning with physics and centered on developing conceptual understanding, using inquiry labs and modeling to allow students to explore new ideas, and addressing and correcting student misconceptions can increase student interest in and preparation for STEM careers. The purpose of this study was to determine if the science college readiness of historically underserved students can be improved by implementing an inquiry-based high school science sequence comprised of coursework in physics, chemistry, and biology for every student. The study used a retrospective cohort observational design to address the primary research question: are there differences between historically underserved students completing a Physics First science sequence and their peers completing a traditional science sequence in 1) science college-readiness test scores, 2) rates of science college-and career-readiness, and 3) interest in STEM? Small positive effects were found for all three outcomes for historically underserved students in the Physics First sequence.

Simultaneous X-ray diffraction and phase-contrast imaging for investigating material deformation mechanisms during high-rate loading

DOE PAGES

Hudspeth, M.; Sun, T.; Parab, N.; ...

2015-01-01

Using a high-speed camera and an intensified charge-coupled device (ICCD), a simultaneous X-ray imaging and diffraction technique has been developed for studying dynamic material behaviors during high-rate tensile loading. A Kolsky tension bar has been used to pull samples at 1000 s –1and 5000 s –1strain-rates for super-elastic equiatomic NiTi and 1100-O series aluminium, respectively. By altering the ICCD gating time, temporal resolutions of 100 ps and 3.37 µs have been achieved in capturing the diffraction patterns of interest, thus equating to single-pulse and 22-pulse X-ray exposure. Furthermore, the sample through-thickness deformation process has been simultaneously imagedviaphase-contrast imaging. It ismore » also shown that adequate signal-to-noise ratios are achieved for the detected white-beam diffraction patterns, thereby allowing sufficient information to perform quantitative data analysis diffractionviain-house software ( WBXRD_GUI). Finally, of current interest is the ability to evaluate crystald-spacing, texture evolution and material phase transitions, all of which will be established from experiments performed at the aforementioned elevated strain-rates.« less

Mind wandering and reading comprehension: examining the roles of working memory capacity, interest, motivation, and topic experience.

PubMed

Unsworth, Nash; McMillan, Brittany D

2013-05-01

Individual differences in mind wandering and reading comprehension were examined in the current study. In particular, individual differences in mind wandering, working memory capacity, interest in the current topic, motivation to do well on the task, and topic experience and their relations with reading comprehension were examined in the current study. Using confirmatory factor analysis and structural equation modeling it was found that variation in mind wandering while reading was influenced by working memory capacity, topic interest, and motivation. Furthermore, these same factors, along with topic experience, influenced individual differences in reading comprehension. Importantly, several factors had direct effects on reading comprehension (and mind wandering), while the relation between reading comprehension (and mind wandering) and other factors occurred via indirect effects. These results suggest that both domain-general and domain-specific factors contribute to mind wandering while reading and to reading comprehension.

A class of semiparametric cure models with current status data.

PubMed

Diao, Guoqing; Yuan, Ao

2018-02-08

Current status data occur in many biomedical studies where we only know whether the event of interest occurs before or after a particular time point. In practice, some subjects may never experience the event of interest, i.e., a certain fraction of the population is cured or is not susceptible to the event of interest. We consider a class of semiparametric transformation cure models for current status data with a survival fraction. This class includes both the proportional hazards and the proportional odds cure models as two special cases. We develop efficient likelihood-based estimation and inference procedures. We show that the maximum likelihood estimators for the regression coefficients are consistent, asymptotically normal, and asymptotically efficient. Simulation studies demonstrate that the proposed methods perform well in finite samples. For illustration, we provide an application of the models to a study on the calcification of the hydrogel intraocular lenses.

Current distribution within parallel-connected battery cells

NASA Astrophysics Data System (ADS)

Brand, Martin J.; Hofmann, Markus H.; Steinhardt, Marco; Schuster, Simon F.; Jossen, Andreas

2016-12-01

Parallel connections can be found in many battery applications. Therefore, it is of high interest to understand how the current distributes within parallel battery cells. However, the number of publications on this topic is comparably low. Furthermore, the measurement set-ups are often not clearly defined in existing publications and it is likely that additional impedances distorted the measured current distributions. In this work, the principles of current distributions within parallel-connected battery cells are investigated theoretically, with an equivalent electric circuit model, and by measurements. A measurement set-up is developed that does not significantly influence the measurements, as proven by impedance spectroscopy. On this basis, two parameter scenarios are analyzed: the ΔR scenario stands for battery cells with differing impedances but similar capacities and the ΔC scenario for differing capacities and similar impedances. Out of 172 brand-new lithium-ion battery cells, pairs are built to practically represent the ΔR and ΔC scenarios. If a charging pulse is applied to the ΔR scenario, currents initially divide according to the current divider but equalize in constant current phases. The current divider has no effect on ΔC pairs but, as a rule of thumb for long-term loads, currents divide according to the battery cell capacities.

Use of the 'Hall technique' for management of carious primary molars among Scottish general dental practitioners.

PubMed

Dean, A A; Bark, J E; Sherriff, A; Macpherson, L M D; Cairns, A

2011-06-01

To assess the current awareness, usage and opinion of the Hall technique as a restorative option for primary molars in Scottish general dental practice; and to identify preferences for methods of further training, if desired, for those not currently using the technique. A postal questionnaire was sent to a random sample of Scottish general dental practitioners (GDPs) (n= 1207). Half of all GDPs within each health board were mailed. All analyses have been carried out in Minitab (version 15). The study is primarily descriptive and uses frequency distributions and cross-tabulations. Percentages are reported with p5% confidence intervals. Characteristics of the whole sample were reported. However when reporting the use of the Hall technique, only those GDP's reporting to treat children, at least sometimes are considered. Following two mail-shots, the overall response rate was 59% (715/1207). Eighty-six percent (616/715) of respondents were aware of the Hall technique as a method of restoring primary molars and 48 % (n=318) were currently using the Hall technique. Of those GDPs who never used the Hall technique (51% of total respondents; n=340), 46% (n=157) indicated they were either 'very interested' or 'interested' in adopting the Hall technique into their clinical practice. The preferred source for further training was via a section 63 continuing professional development (CPD) course, incorporating a practical element. Of those GDPs in Scotland who responded to the questionnaire, an unexpectedly high number were already using the Hall technique in their practice, and among those not currently using it, there is a demand for training.

Interest and use of mental health and specialty behavioral medicine counseling in US primary care patients.

PubMed

Baron, Kelly G; Lattie, Emily; Ho, Joyce; Mohr, David C

2013-03-01

Counseling interventions have the potential to improve health and quality of life for primary care patients, but there are few studies describing the interest in and utilization of counseling among this patient population in the USA. The purpose of the study was to evaluate interest in mental health and specialty behavioral medicine counseling and predictors of utilization over 1 year among US primary care patients. Participants in this two-survey longitudinal study included 658 primary care patients in an urban US academic medical center (461 females, age M = 51.05, SD = 15.46 years). Retention rate was 61.2% at survey 2. Patient demographics, depression, anxiety, and interest in counseling services were assessed through a survey mailed 1 week following an outpatient appointment. Respondents to survey 1 were re-contacted 1 year later to assess. Interest and use of the following counseling services were evaluated in the relevant subgroups: mental health (the entire sample and patients with elevated anxiety and/or depression), health/lifestyle (overweight and obese participants), smoking cessation (current and occasional smokers), and pain management (participants with elevated daily pain ratings). At survey 1, 45.7% of the sample reported interest in mental health counseling, and 58.9% of the sample reported interest in behavioral medicine counseling. Among overweight or obese participants, 59.9% were interested in health/lifestyle counseling. Among smokers, 55.3% were interested in smoking cessation, and among participants with chronic pain, 33.8% were interest in pain management. Rates of utilization of services at survey 2 were 21.3% for mental health, 7.7% for health/lifestyle, 6.7% for smoking cessation, and 6.6% for pain management. Interest in receiving services at survey 1 was the strongest predictor of utilization. Results demonstrate high interest but low utilization over 1 year among US primary care patients. Identifying patients interested in counseling services and reducing barriers may help facilitate receipt of services for those with interest and need for behavioral treatments.

A novel durable double-conductive core-shell structure applying to the synthesis of silicon anode for lithium ion batteries

NASA Astrophysics Data System (ADS)

Xing, Yan; Shen, Tong; Guo, Ting; Wang, Xiuli; Xia, Xinhui; Gu, Changdong; Tu, Jiangping

2018-04-01

Si/C composites are currently the most commercially viable next-generation lithium-ion battery anode materials due to their high specific capacity. However, there are still many obstacles need to be overcome such as short cycle life and poor conductivity. In this work, we design and successfully synthesis an excellent durable double-conductive core-shell structure p-Si-Ag/C composites. Interestingly, this well-designed structure offers remarkable conductivity (both internal and external) due to the introduction of silver particles and carbon layer. The carbon layer acts as a protective layer to maintain the integrity of the structure as well as avoids the direct contact of silicon with electrolyte. As a result, the durable double-conductive core-shell structure p-Si-Ag/C composites exhibit outstanding cycling stability of roughly 1000 mAh g-1 after 200 cycles at a current density of 0.2 A g-1 and retain 765 mAh g-1 even at a high current density of 2 A g-1, indicating a great improvement in electrochemical performance compared with traditional silicon electrode. Our research results provide a novel pathway for production of high-performance Si-based anodes to extending the cycle life and specific capacity of commercial lithium ion batteries.

Single-graded CIGS with narrow bandgap for tandem solar cells.

PubMed

Feurer, Thomas; Bissig, Benjamin; Weiss, Thomas P; Carron, Romain; Avancini, Enrico; Löckinger, Johannes; Buecheler, Stephan; Tiwari, Ayodhya N

2018-01-01

Multi-junction solar cells show the highest photovoltaic energy conversion efficiencies, but the current technologies based on wafers and epitaxial growth of multiple layers are very costly. Therefore, there is a high interest in realizing multi-junction tandem devices based on cost-effective thin film technologies. While the efficiency of such devices has been limited so far because of the rather low efficiency of semitransparent wide bandgap top cells, the recent rise of wide bandgap perovskite solar cells has inspired the development of new thin film tandem solar devices. In order to realize monolithic, and therefore current-matched thin film tandem solar cells, a bottom cell with narrow bandgap (~1 eV) and high efficiency is necessary. In this work, we present Cu(In,Ga)Se 2 with a bandgap of 1.00 eV and a maximum power conversion efficiency of 16.1%. This is achieved by implementing a gallium grading towards the back contact into a CuInSe 2 base material. We show that this modification significantly improves the open circuit voltage but does not reduce the spectral response range of these devices. Therefore, efficient cells with narrow bandgap absorbers are obtained, yielding the high current density necessary for thin film multi-junction solar cells.

Nitrated carbon nanoblisters for high-performance glucose dehydrogenase bioanodes.

PubMed

de Souza, João C P; Iost, Rodrigo M; Crespilho, Frank N

2016-03-15

Recently, many strategies are being explored for efficiently wiring glucose dehydrogenase (GDh) enzymes capable of glucose (fuel) oxidation. For instance, the use of GDh NAD(+)-dependent for glucose oxidation is of great interest in biofuel cell technology because the enzyme are unaffected by the presence of molecular oxygen commonly present in electrolyte. Here we present the fabrication of flexible carbon fibers modified with nitrated carbon nanoblisters and their application as high-performance GDh bioanodes. These bioelectrodes could electro-oxidize glucose at -360 mV (vs. Ag/AgClsat) in the presence of a molecular oxygen saturated electrolyte with current densities higher than 1.0 mAcm(-2) at 0.0 V. It is corroborated by open circuit potential, where a potential stabilization occurs at -150 mV in a long term stability current-transient experiment. This value is in agreement with the quasi-steady current obtained at very low scan rate (0.1 mVs(-1)), where the onset potential for glucose oxidation is -180 mV. X-ray photoelectron spectroscopy and scanning electron microscopy revealed that the nitrated blisters and edge-like carbon structures, enabling highly efficient enzyme immobilization and low overpotential for electron transfer, allowing for glucose oxidation with potential values close to the thermodynamic cofactor. Copyright © 2015 Elsevier B.V. All rights reserved.

Single-graded CIGS with narrow bandgap for tandem solar cells

PubMed Central

Avancini, Enrico; Buecheler, Stephan; Tiwari, Ayodhya N.

2018-01-01

Abstract Multi-junction solar cells show the highest photovoltaic energy conversion efficiencies, but the current technologies based on wafers and epitaxial growth of multiple layers are very costly. Therefore, there is a high interest in realizing multi-junction tandem devices based on cost-effective thin film technologies. While the efficiency of such devices has been limited so far because of the rather low efficiency of semitransparent wide bandgap top cells, the recent rise of wide bandgap perovskite solar cells has inspired the development of new thin film tandem solar devices. In order to realize monolithic, and therefore current-matched thin film tandem solar cells, a bottom cell with narrow bandgap (~1 eV) and high efficiency is necessary. In this work, we present Cu(In,Ga)Se2 with a bandgap of 1.00 eV and a maximum power conversion efficiency of 16.1%. This is achieved by implementing a gallium grading towards the back contact into a CuInSe2 base material. We show that this modification significantly improves the open circuit voltage but does not reduce the spectral response range of these devices. Therefore, efficient cells with narrow bandgap absorbers are obtained, yielding the high current density necessary for thin film multi-junction solar cells. PMID:29707066

Connecting families and high schools through interactive homework

NASA Astrophysics Data System (ADS)

Pandya, Katrina

2008-10-01

The current study analyzed the effectiveness of integrating parents in the education of their children through interactive homework (IH). More specifically, the research questions of the study examined the effectiveness, feasibility, and usefulness of parental involvement in increasing academic performance within high school science classes. Using a mixed method design with a single IH treatment group, a convenience sample of 84 anatomy and biology students was assessed over a 6-week period. Although Spearman correlations failed to reveal any associations linking hours of parental IH involvement with student outcomes, related-samples t tests of pre/post student performance indicated significant increases in homework, test scores and overall grades, with greatest improvement observed in test scores. Exit questionnaires, focus groups, and interviews were coded for emergent themes that in turn were analyzed for common patterns. These qualitative data revealed positive feedback related to specific program components and a general interest for program continuation. The results indicated that it is possible to successfully incorporate parents at the high school level, even in technical subject areas. The research may be of particular interest to families and educators due to the positive scholastic effects of incorporating parents in high school academics. Social change is generated by incorporating parents into the educational process which strengthens the school-home bond and contributes to student achievement and motivation.

Kinetic Simulations of Current-Sheet Formation and Reconnection at a Magnetic X Line

NASA Technical Reports Server (NTRS)

Black, C.; Antiochos, S. K.; Hesse, M.; Karpen, J. T.; DeVore, C. R.; Kuznetsova, M. M.; Zenitani, S.

2011-01-01

The integration of kinetic effects into macroscopic numerical models is currently of great interest to the plasma physics community, particularly in the context of magnetic reconnection. We are examining the formation and reconnection of current sheets in a simple, two-dimensional X-line configuration using high resolution particle-in-cell (PIC) simulations. The initial potential magnetic field is perturbed by thermal pressure introduced into the particle distribution far from the X line. The relaxation of this added stress leads to the development of a current sheet, which reconnects for imposed stress of sufficient strength. We compare the evolution and final state of our PIC simulations with magnetohydrodynamic simulations assuming both uniform and localized resistivities, and with force-free magnetic-field equilibria in which the amount of reconnect ion across the X line can be constrained to be zero (ideal evolution) or optimal (minimum final magnetic energy). We will discuss implications of our results for reconnection onset and cessation at kinetic scales in dynamically formed current sheets, such as those occurring in the terrestrial magnetotail and solar corona.

Eddy current spectroscopy for near-surface residual stress profiling in surface treated nonmagnetic engine alloys

NASA Astrophysics Data System (ADS)

Abu-Nabah, Bassam A.

Recent research results indicated that eddy current conductivity measurements can be exploited for nondestructive evaluation of near-surface residual stresses in surface-treated nickel-base superalloy components. Most of the previous experimental studies were conducted on highly peened (Almen 10-16A) specimens that exhibit harmful cold work in excess of 30% plastic strain. Such high level of cold work causes thermo-mechanical relaxation at relatively modest operational temperatures; therefore the obtained results were not directly relevant to engine manufacturers and end users. The main reason for choosing peening intensities in excess of recommended normal levels was that in low-conductivity engine alloys the eddy current penetration depth could not be forced below 0.2 mm without expanding the measurements above 10 MHz which is beyond the operational range of most commercial eddy current instruments. As for shot-peened components, it was initially felt that the residual stress effect was more difficult to separate from cold work, texture, and inhomogeneity effects in titanium alloys than in nickel-base superalloys. In addition, titanium alloys have almost 50% lower electric conductivity than nickel-base superalloys; therefore require proportionally higher inspection frequencies, which was not feasible until our recent breakthrough in instrument development. Our work has been focused on six main aspects of this continuing research, namely, (i) the development of an iterative inversion technique to better retrieve the depth-dependent conductivity profile from the measured frequency-dependent apparent eddy current conductivity (AECC), (ii) the extension of the frequency range up to 80 MHz to better capture the peak compressive residual stress in nickel-base superalloys using a new eddy current conductivity measuring system, which offers better reproducibility, accuracy and measurement speed than the previously used conventional systems, (iii) the lift-off effect on high frequency eddy current spectroscopy, (iv) the development of custom-made spiral coils to allow eddy current conductivity characterization over the whole frequency range of interest with reduced coil sensitivity to lift off, (v) the benefits of implementing a semi-quadratic system calibration in reducing the coil sensitivity to lift-off, and (vi) the feasibility of adapting high-frequency eddy current residual stress characterization for shot-peened titanium alloys.

Designing microorganisms for heterologous biosynthesis of cannabinoids

PubMed Central

Carvalho, Ângela; Hansen, Esben Halkjær; Kayser, Oliver; Stehle, Felix

2017-01-01

Abstract During the last decade, the use of medical Cannabis has expanded globally and legislation is getting more liberal in many countries, facilitating the research on cannabinoids. The unique interaction of cannabinoids with the human endocannabinoid system makes these compounds an interesting target to be studied as therapeutic agents for the treatment of several medical conditions. However, currently there are important limitations in the study, production and use of cannabinoids as pharmaceutical drugs. Besides the main constituent tetrahydrocannabinolic acid, the structurally related compound cannabidiol is of high interest as drug candidate. From the more than 100 known cannabinoids reported, most can only be extracted in very low amounts and their pharmacological profile has not been determined. Today, cannabinoids are isolated from the strictly regulated Cannabis plant, and the supply of compounds with sufficient quality is a major problem. Biotechnological production could be an attractive alternative mode of production. Herein, we explore the potential use of synthetic biology as an alternative strategy for synthesis of cannabinoids in heterologous hosts. We summarize the current knowledge surrounding cannabinoids biosynthesis and present a comprehensive description of the key steps of the genuine and artificial pathway, systems biotechnology needs and platform optimization. PMID:28582498

Designing microorganisms for heterologous biosynthesis of cannabinoids.

PubMed

Carvalho, Ângela; Hansen, Esben Halkjær; Kayser, Oliver; Carlsen, Simon; Stehle, Felix

2017-06-01

During the last decade, the use of medical Cannabis has expanded globally and legislation is getting more liberal in many countries, facilitating the research on cannabinoids. The unique interaction of cannabinoids with the human endocannabinoid system makes these compounds an interesting target to be studied as therapeutic agents for the treatment of several medical conditions. However, currently there are important limitations in the study, production and use of cannabinoids as pharmaceutical drugs. Besides the main constituent tetrahydrocannabinolic acid, the structurally related compound cannabidiol is of high interest as drug candidate. From the more than 100 known cannabinoids reported, most can only be extracted in very low amounts and their pharmacological profile has not been determined. Today, cannabinoids are isolated from the strictly regulated Cannabis plant, and the supply of compounds with sufficient quality is a major problem. Biotechnological production could be an attractive alternative mode of production. Herein, we explore the potential use of synthetic biology as an alternative strategy for synthesis of cannabinoids in heterologous hosts. We summarize the current knowledge surrounding cannabinoids biosynthesis and present a comprehensive description of the key steps of the genuine and artificial pathway, systems biotechnology needs and platform optimization. © FEMS 2017.

Development of an Acoustic Localization Method for Cavitation Experiments in Reverberant Environments

NASA Astrophysics Data System (ADS)

Ranjeva, Minna; Thompson, Lee; Perlitz, Daniel; Bonness, William; Capone, Dean; Elbing, Brian

2011-11-01

Cavitation is a major concern for the US Navy since it can cause ship damage and produce unwanted noise. The ability to precisely locate cavitation onset in laboratory scale experiments is essential for proper design that will minimize this undesired phenomenon. Measuring the cavitation onset is more accurately determined acoustically than visually. However, if other parts of the model begin to cavitate prior to the component of interest the acoustic data is contaminated with spurious noise. Consequently, cavitation onset is widely determined by optically locating the event of interest. The current research effort aims at developing an acoustic localization scheme for reverberant environments such as water tunnels. Currently cavitation bubbles are being induced in a static water tank with a laser, allowing the localization techniques to be refined with the bubble at a known location. The source is located with the use of acoustic data collected with hydrophones and analyzed using signal processing techniques. To verify the accuracy of the acoustic scheme, the events are simultaneously monitored visually with the use of a high speed camera. Once refined testing will be conducted in a water tunnel. This research was sponsored by the Naval Engineering Education Center (NEEC).

Ab Initio Potential Energy Surfaces and Quantum Dynamics for Polyatomic Bimolecular Reactions.

PubMed

Fu, Bina; Zhang, Dong H

2018-05-08

There has been great progress in the development of potential energy surfaces (PESs) and quantum dynamics calculations in the gas phase. The establishment of a fitting procedure for highly accurate PESs and new developments in quantum reactive scattering on reliable PESs allow accurate characterization of reaction dynamics beyond triatomic systems. This review will give the recent development in our group in constructing ab initio PESs based on neural networks and the time-dependent wave packet calculations for bimolecular reactions beyond three atoms. Bimolecular reactions of current interest to the community, namely, OH + H 2 , H + H 2 O, OH + CO, H + CH 4 , and Cl + CH 4 , are focused on. Quantum mechanical characterization of these reactions uncovers interesting dynamical phenomena with an unprecedented level of sophistication and has greatly advanced our understanding of polyatomic reaction dynamics.

The TMT instrumentation program

NASA Astrophysics Data System (ADS)

Simard, Luc; Crampton, David; Ellerbroek, Brent; Boyer, Corinne

2010-07-01

An overview of the current status of the Thirty Meter Telescope (TMT) instrumentation program is presented. Conceptual designs for the three first light instruments (IRIS, WFOS and IRMS) are in progress, as well as feasibility studies of MIRES. Considerable effort is underway to understand the end-to-end performance of the complete telescopeadaptive optics-instrument system under realistic conditions on Mauna Kea. Highly efficient operation is being designed into the TMT system, based on a detailed investigation of the observation workflow to ensure very fast target acquisition and set up of all subsystems. Future TMT instruments will almost certainly involve contributions from institutions in many different locations in North America and partner nations. Coordinating and optimizing the design and construction of the instruments to ensure delivery of the best possible scientific capabilities is an interesting challenge. TMT welcomes involvement from all interested instrument teams.

Smooth Sailing for Weather Forecasting

NASA Technical Reports Server (NTRS)

2002-01-01

Through a cooperative venture with NASA's Stennis Space Center, WorldWinds, Inc., developed a unique weather and wave vector map using space-based radar satellite information and traditional weather observations. Called WorldWinds, the product provides accurate, near real-time, high-resolution weather forecasts. It was developed for commercial and scientific users. In addition to weather forecasting, the product's applications include maritime and terrestrial transportation, aviation operations, precision farming, offshore oil and gas operations, and coastal hazard response support. Target commercial markets include the operational maritime and aviation communities, oil and gas providers, and recreational yachting interests. Science applications include global long-term prediction and climate change, land-cover and land-use change, and natural hazard issues. Commercial airlines have expressed interest in the product, as it can provide forecasts over remote areas. WorldWinds, Inc., is currently providing its product to commercial weather outlets.

Solvent effects on polysulfide redox kinetics and ionic conductivity in lithium-sulfur batteries

DOE PAGES

Fan, Frank Y.; Pan, Menghsuan Sam; Lau, Kah Chun; ...

2016-11-25

Lithium-sulfur (Li-S) batteries have high theoretical energy density and low raw materials cost compared to present lithium-ion batteries and are thus promising for use in electric transportation and other applications. A major obstacle for Li-S batteries is low rate capability, especially at the low electrolyte/sulfur (E/S) ratios required for high energy density. Herein, we investigate several potentially rate-limiting factors for Li-S batteries. We study the ionic conductivity of lithium polysulfide solutions of varying concentration and in different ether-based solvents and their exchange current density on glassy carbon working electrodes. We believe this is the first such investigation of exchange currentmore » density for lithium polysulfide in solution. Exchange current densities are measured using both electrochemical impedance spectroscopy and steady-state galvanostatic polarization. In the range of interest (1-8 M [S]), the ionic conductivity monotonically decreases with increasing sulfur concentration while exchange current density shows a more complicated relationship to sulfur concentration. The electrolyte solvent dramatically affects ionic conductivity and exchange current density. Finally, the measured ionic conductivities and exchange current densities are also used to interpret the overpotential and rate capability of polysulfide-nanocarbon suspensions; this analysis demonstrates that ionic conductivity is the rate-limiting property in the solution regime (i.e. between Li 2S 8 and Li 2S 4).« less

Spatially resolved, in-situ monitoring of crack growth via the coupling current in aluminum alloy 5083

NASA Astrophysics Data System (ADS)

Williams, Krystaufeux D.

The work discussed in this dissertation is an experimental validation of a body of research that was created to model stress corrosion cracking phenomenon for 304 stainless steels in boiling water reactors. This coupled environment fracture model (CEFM) incorporates the natural laws of the conservation of charge and the differential aeration hypothesis to predict the amount of stress corrosion crack growth as a function of many external environmental variables, including potential, stress intensity, solution conductivity, oxidizer concentrations, and various other environmental parameters. Out of this approach came the concept of the coupling current; a local corrosion current that flows from within cracks, crevices, pits, etc... of a metal or alloy to the external surface. Because of the deterministic approach taken in the mentioned research, the coupling current analysis and CEFM model can be applied to the specific problem of SCC in aluminum alloy 5083 (the alloy of interest for this dissertation that is highly sought after today because of its corrosion resistance and high strength to weight ratio). This dissertation research is specifically devoted to the experimental verification of the coupling current, which results from a coupling between the crack's internal and external environments, by spatially resolving them using the scanning vibrating probe (SVP) as a tool. Hence, through the use of a unique fracture mechanics setup, simultaneous mechanical and local electrochemical data may be obtained, in situ..

Storm- Time Dynamics of Ring Current Protons: Implications for the Long-Term Energy Budget in the Inner Magnetosphere.

NASA Astrophysics Data System (ADS)

Gkioulidou, M.; Ukhorskiy, A. Y.; Mitchell, D. G.; Lanzerotti, L. J.

2015-12-01

The ring current energy budget plays a key role in the global electrodynamics of Earth's space environment. Pressure gradients developed in the inner magnetosphere can shield the near-Earth region from solar wind-induced electric fields. The distortion of Earth's magnetic field due to the ring current affects the dynamics of particles contributing both to the ring current and radiation belts. Therefore, understanding the long-term evolution of the inner magnetosphere energy content is essential. We have investigated the evolution of ring current proton pressure (7 - 600 keV) in the inner magnetosphere based on data from the Radiation Belt Storm Probes Ion Composition Experiment (RBSPICE) instrument aboard Van Allen Probe B throughout the year 2013. We find that although the low-energy component of the protons (< 80 keV) is governed by convective timescales and is very well correlated with the Dst index, the high-energy component (>100 keV) varies on much longer timescales and shows either no or anti-correlation with the Dst index. Interestingly, the contributions of the high- and low-energy protons to the total energy content are comparable. Our results indicate that the proton dynamics, and as a consequence the total energy budget in the inner magnetosphere (inside geosynchronous orbit), is not strictly controlled by storm-time timescales as those are defined by the Dst index.

ICan: An Optimized Ion-Current-Based Quantification Procedure with Enhanced Quantitative Accuracy and Sensitivity in Biomarker Discovery

PubMed Central

2015-01-01

The rapidly expanding availability of high-resolution mass spectrometry has substantially enhanced the ion-current-based relative quantification techniques. Despite the increasing interest in ion-current-based methods, quantitative sensitivity, accuracy, and false discovery rate remain the major concerns; consequently, comprehensive evaluation and development in these regards are urgently needed. Here we describe an integrated, new procedure for data normalization and protein ratio estimation, termed ICan, for improved ion-current-based analysis of data generated by high-resolution mass spectrometry (MS). ICan achieved significantly better accuracy and precision, and lower false-positive rate for discovering altered proteins, over current popular pipelines. A spiked-in experiment was used to evaluate the performance of ICan to detect small changes. In this study E. coli extracts were spiked with moderate-abundance proteins from human plasma (MAP, enriched by IgY14-SuperMix procedure) at two different levels to set a small change of 1.5-fold. Forty-five (92%, with an average ratio of 1.71 ± 0.13) of 49 identified MAP protein (i.e., the true positives) and none of the reference proteins (1.0-fold) were determined as significantly altered proteins, with cutoff thresholds of ≥1.3-fold change and p ≤ 0.05. This is the first study to evaluate and prove competitive performance of the ion-current-based approach for assigning significance to proteins with small changes. By comparison, other methods showed remarkably inferior performance. ICan can be broadly applicable to reliable and sensitive proteomic survey of multiple biological samples with the use of high-resolution MS. Moreover, many key features evaluated and optimized here such as normalization, protein ratio determination, and statistical analyses are also valuable for data analysis by isotope-labeling methods. PMID:25285707

Are personality differences in a small iteroparous mammal maintained by a life-history trade-off?

PubMed Central

Dammhahn, Melanie

2012-01-01

Despite increasing interest, animal personality is still a puzzling phenomenon. Several theoretical models have been proposed to explain intraindividual consistency and interindividual variation in behaviour, which have been primarily supported by qualitative data and simulations. Using an empirical approach, I tested predictions of one main life-history hypothesis, which posits that consistent individual differences in behaviour are favoured by a trade-off between current and future reproduction. Data on life-history were collected for individuals of a natural population of grey mouse lemurs (Microcebus murinus). Using open-field and novel-object tests, I quantified variation in activity, exploration and boldness for 117 individuals over 3 years. I found systematic variation in boldness between individuals of different residual reproductive value. Young males with low current but high expected future fitness were less bold than older males with high current fecundity, and males might increase in boldness with age. Females have low variation in assets and in boldness with age. Body condition was not related to boldness and only explained marginal variation in exploration. Overall, these data indicate that a trade-off between current and future reproduction might maintain personality variation in mouse lemurs, and thus provide empirical support of this life-history trade-off hypothesis. PMID:22398164

49 CFR 236.2 - Grounds.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., single-break, signal control circuits using a grounded common, and alternating current power distribution...) Alternating current power distribution circuits that are grounded in the interest of safety. ...

SiC Seeded Crystal Growth

NASA Astrophysics Data System (ADS)

Glass, R. C.; Henshall, D.; Tsvetkov, V. F.; Carter, C. H., Jr.

1997-07-01

The availability of relatively large (30 mm) SiC wafers has been a primary reason for the renewed high level of interest in SiC semiconductor technology. Projections that 75 mm SiC wafers will be available in 2 to 3 years have further peaked this interest. Now both 4H and 6H polytypes are available, however, the micropipe defects that occur to a varying extent in all wafers produced to date are seen by many as preventing the commercialization of many types of SiC devices, especially high current power devices. Most views on micropipe formation are based around Frank's theory of a micropipe being the hollow core of a screw dislocation with a huge Burgers vector (several times the unit cell) and with the diameter of the core having a direct relationship with the magnitude of the Burgers vector. Our results show that there are several mechanisms or combinations of these mechanisms which cause micropipes in SiC boules grown by the seeded sublimation method. Additional considerations such as polytype variations, dislocations and both impurity and diameter control add to the complexity of producing high quality wafers. Recent results at Cree Research, Inc., including wafers with micropipe densities of less than 1 cm - 2 (with 1 cm2 areas void of micropipes), indicate that micropipes will be reduced to a level that makes high current devices viable and that they may be totally eliminated in the next few years. Additionally, efforts towards larger diameter high quality substrates have led to production of 50 mm diameter 4H and 6H wafers for fabrication of LEDs and the demonstration of 75 mm wafers. Low resistivity and semi-insulating electrical properties have also been attained through improved process and impurity control. Although challenges remain, the industry continues to make significant progress towards large volume SiC-based semiconductor fabrication.

Ab-initio Pulsar Magnetosphere: Particle Acceleration in Oblique Rotators and High-energy Emission Modeling

NASA Astrophysics Data System (ADS)

Philippov, Alexander A.; Spitkovsky, Anatoly

2018-03-01

We perform global particle-in-cell simulations of pulsar magnetospheres, including pair production, ion extraction from the surface, frame-dragging corrections, and high-energy photon emission and propagation. In the case of oblique rotators, the effects of general relativity increase the fraction of the open field lines that support active pair discharge. We find that the plasma density and particle energy flux in the pulsar wind are highly non-uniform with latitude. A significant fraction of the outgoing particle energy flux is carried by energetic ions, which are extracted from the stellar surface. Their energies may extend up to a large fraction of the open field line voltage, making them interesting candidates for ultra-high-energy cosmic rays. We show that pulsar gamma-ray radiation is dominated by synchrotron emission, produced by particles that are energized by relativistic magnetic reconnection close to the Y-point and in the equatorial current sheet. In most cases, the calculated light curves contain two strong peaks, which is in general agreement with Fermi observations. The radiative efficiency decreases with increasing pulsar inclination and increasing efficiency of pair production in the current sheet, which explains the observed scatter in L γ versus \\dot{E}. We find that the high-frequency cutoff in the spectra is regulated by the pair-loading of the current sheet. Our findings lay the foundation for quantitative interpretation of Fermi observations of gamma-ray pulsars.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Majetich, Sara

In the proposed research program we will investigate the time- and frequency-dependent behavior of ordered nanoparticle assemblies, or nanoparticle crystals. Magnetostatic interactions are long-range and anisotropic, and this leads to complex behavior in nanoparticle assemblies, particularly in the time- and frequency-dependent properties. We hypothesize that the high frequency performance of composite materials has been limited because of the range of relaxation times; if a composite is a dipolar ferromagnet at a particular frequency, it should have the advantages of a single phase material, but without significant eddy current power losses. Arrays of surfactant-coated monodomain magnetic nanoparticles can exhibit long-range magneticmore » order that is stable over time. The magnetic domain size and location of domain walls is governed not by structural grain boundaries but by the shape of the array, due to the local interaction field. Pores or gaps within an assembly pin domain walls and limit the domain size. Measurements of the magnetic order parameter as a function of temperature showed that domains can exist at high temoerature, and that there is a collective phase transition, just as in an exchange-coupled ferromagnet. Dipolar ferromagnets are not merely of fundamental interest; they provide an interesting alternative to exchange-based ferromagnets. Dipolar ferromagnets made with high moment metallic particles in an insulating matrix could have high permeability without large eddy current losses. Such nanocomposites could someday replace the ferrites now used in phase shifters, isolators, circulators, and filters in microwave communications and radar applications. We will investigate the time- and frequency-dependent behavior of nanoparticle crystals with different magnetic core sizes and different interparticle barrier resistances, and will measure the magnetic and electrical properties in the DC, low frequency (0.1 Hz - 1 kHz), moderate frequency (10 Hz - 500 MHz), and high frequency (up to 20 GHz) regimes. Our results will demonstrate whether a DC dipolar ferromagnet shows collective frequency-dependent reponse similar to that of an exchange-based ferromagnet, and will provide data for comparison of optimal nanocomposite properties with those of ferrites used in high frequency applications. Both the magnetic and electronic response of the composites will be examined in order to determine the frequency range where hopping conductivity leads to significant eddy current power losses. In the high frequency regime we will look for evidence of spin wave quantization and the resulting decrease in non-linear spin wave processes that could affect the performance of high frequency magnetic devices.« less

Dose-current discharge correlation analysis in a Mather type Plasma Focus device for medical applications

NASA Astrophysics Data System (ADS)

Sumini, M.; Mostacci, D.; Tartari, A.; Mazza, A.; Cucchi, G.; Isolan, L.; Buontempo, F.; Zironi, I.; Castellani, G.

2017-11-01

In a Plasma Focus device the plasma collapses into the pinch where it reaches thermonuclear conditions for a few tens of nanoseconds, becoming a multi-radiation source. The nature of the radiation generated depends on the gas filling the chamber and the device working parameters. The self-collimated electron beam generated in the backward direction with respect to the plasma motion is one of the main radiation sources of interest also for medical applications. The electron beam may be guided against a high Z material target to produce an X-ray beam. This technique offers an ultra-high dose rate source of X-rays, able to deliver during the pinch a massive dose (up to 1 Gy per discharge for the PFMA-3 test device), as measured with EBT3 GafchromicⒸfilm tissue equivalent dosimeters. Given the stochastic behavior of the discharge process, a reliable on-line estimate of the dose-delivered is a very challenging task, in some way preventing a systematic application as a potentially interesting therapy device. This work presents an approach to linking the dose registered by the EBT3 GafchromicⒸfilms with the information contained in the signal recorded during the current discharge process. Processing the signal with the Wigner-Ville distribution, a spectrogram was obtained, displaying the information on intensity at various frequency scales, identifying the band of frequencies representative of the pinch events and define some patterns correlated with the dose.

Cloning by limiting dilution: an improved estimate that an interesting culture is monoclonal.

PubMed Central

Staszewski, R.

1984-01-01

An interesting culture obtained by limiting dilution is less likely to be monoclonal than a random viable culture. Current practice using limiting dilution to establish monoclonal lines of interesting recombinant DNA or hybridoma-derived organisms overestimates the probability that promising cultures are monoclonal, resulting in inadequate dilutions, with the need for additional subcloning and the avoidable loss (avoidable instability) of interesting lines by overgrowth with uninteresting varieties. PMID:6537695

Deposition SnO(2)/nitrogen-doped graphene nanocomposites on the separator: a new type of flexible electrode for energy storage devices.

PubMed

Liang, Junfei; Cai, Zhi; Tian, Yu; Li, Lidong; Geng, Jianxin; Guo, Lin

2013-11-27

It is currently very urgent to develop flexible energy storage devices because of the growing academic interest in and strong technical demand of flexible electronics. Exploration of high-performance electrode materials and a corresponding assembly method for fabrication of flexible energy storage devices plays a critical role in fulfilling this demand. Here, we have developed a facile, economic, and green hydrothermal process to synthesize ultrasmall SnO2 nanocrystallites/nitrogen-doped graphene nanocomposites (USNGs) as a high-performance electrode material for Li-ion batteries (LIBs). Furthermore, using the glass microfiber filters (GMFs) as supporting substrate, the novel flexible USNG-GMF bilayered films have been prepared by depositing the as-prepared USNG on GMF through a simple vacuum filtration. Significantly, for the first time, the flexible USNG-GMF bilayered films have directly been used for assembling LIBs, where the GMF further functions as a separator. The obtained highly robust, binder-free, conducting agent-free, and current collector-free new type of flexible electrodes show excellent LIB performance.

Development of Residual Gas Profile Monitors at GSI

NASA Astrophysics Data System (ADS)

Giacomini, T.; Barabin, S.; Forck, P.; Liakin, D.; Skachkov, V.

2004-11-01

Beam profile measurements at modern ion synchrotrons and storage rings require high timing performances on a turn-by-turn basis. High spatial resolutions are essential for cold beams and beamwidth measurings. The currently used RGM supported very interesting measurements and applications. Due to the readout technology the spatial and time resolution is limited. To meet the expanded demands a more comprehensive device is under development. It will be an all-purpose residual gas monitor to cover the wide range of beam currents and transversal particle distributions. Due to the fast profile detection it will operate on primary electrons after residual gas ionization. A magnetic field of 100 mT binds them to the ionization point inside 0.1-mm orbits. The high-resolution mode will be read out by a digital CCD camera with an upstream MCP-phosphor screen assembly. It is planned to read out the fast turn-by-turn mode by an array of 100 photodiodes with a resolution of 1 mm. Every photodiode is equipped with an amplifier-digitizer device providing a frame rate of ˜ 10 MSamples/s.

High Tc SQUIDs and eddy-current NDE: a comprehensive investigation from real data to modelling

NASA Astrophysics Data System (ADS)

Ruosi, A.; Valentino, M.; Pepe, G.; Monebhurrun, V.; Lesselier, D.; Duchêne, B.

2000-11-01

The interest in magnetometry for eddy-current non-destructive testing, e.g. of planar conductive structures encountered in the aircraft industry, using high-temperature superconducting quantum interference devices (SQUIDs) is primarily due to their high sensitivity to magnetic flux even at very low frequencies. Here it is shown how theoretical, numerical and measurement machineries are combined to get reasonable synthetic and experimental data and to reach a good understanding of the interaction of diffusive wavefields with a damaged non-magnetic metal plate (as a first step towards the retrieval of pertinent features of the defects). The measurement modalities are considered first. It is illustrated in some detail how laboratory-controlled experiments are performed by a SQUID-based probe displaced above artificially damaged plates. Experimental data are then confronted with simulation results in order to evaluate the accuracy and reliability of this measurement system. Simulations are carried out by a computationally fast vector volume integral method dedicated to a planar layering affected by a volumetric defect, which involves the construction of the dyadic Green system of the layering.

Different Technical Applications of Carbon Nanotubes.

PubMed

Abdalla, S; Al-Marzouki, F; Al-Ghamdi, Ahmed A; Abdel-Daiem, A

2015-12-01

Carbon nanotubes have been of great interest because of their simplicity and ease of synthesis. The novel properties of nanostructured carbon nanotubes such as high surface area, good stiffness, and resilience have been explored in many engineering applications. Research on carbon nanotubes have shown the application in the field of energy storage, hydrogen storage, electrochemical supercapacitor, field-emitting devices, transistors, nanoprobes and sensors, composite material, templates, etc. For commercial applications, large quantities and high purity of carbon nanotubes are needed. Different types of carbon nanotubes can be synthesized in various ways. The most common techniques currently practiced are arc discharge, laser ablation, and chemical vapor deposition and flame synthesis. The purification of CNTs is carried out using various techniques mainly oxidation, acid treatment, annealing, sonication, filtering chemical functionalization, etc. However, high-purity purification techniques still have to be developed. Real applications are still under development. This paper addresses the current research on the challenges that are associated with synthesis methods, purification methods, and dispersion and toxicity of CNTs within the scope of different engineering applications, energy, and environmental impact.

The Nature of Experiences Responsible for the Generation and Maintenance of Interest in STEM

ERIC Educational Resources Information Center

Maltese, Adam V.; Melki, Christina S.; Wiebke, Heidi L.

2014-01-01

Previous research has established the importance of early interest in STEM as a key factor in persistence. Our current research builds on this foundation and extends it to add more detail to understanding the types of experiences that trigger and maintain interest in science, technology, engineering, and mathematics (STEM). Using survey data from…

Career Interest Characterizing and Reporting System. May 1, 1976 - May 31, 1977. Final Report.

ERIC Educational Resources Information Center

Texas State Technical Inst., Waco.

A study was conducted to update the existing Career Interest Characterizing (CIC) instrument in terms of current career choices of students and to implement the survey instrument in the Texas secondary school counseling programs. The CIC instrument defines career interests of secondary school students and yields information of value in counseling…

Need for and Interest in a Sports Nutrition Mobile Device Application Among Division I Collegiate Athletes.

PubMed

Zuniga, Krystle E; Downey, Darcy L; McCluskey, Ryan; Rivers, Carley

2017-02-01

The majority of National Collegiate Athletic Association (NCAA) programs do not have a sports nutritionist, leaving athletes to gather information from resources that vary in reputability. The objective of this study was to identify a need for the development of accessible and reputable resources of nutrition information by assessing the current use of nutrition information resources, dietary habits, and sports nutrition knowledge among Division I collegiate athletes. Seventy-two athletes across eight sports completed questionnaires concerning nutrition resources used, dietary habits, and sports nutrition knowledge. In addition, interest levels in a mobile device application for delivery of nutrition information and tools were assessed. Primary sources for nutrition information included parents and family, athletic trainers (AT), and the internet/media, and athletes felt most comfortable discussing nutrition with parents and family, ATs, and strength and conditioning specialists. Performance on a sports nutrition knowledge questionnaire indicated a general lack of nutrition knowledge, and the high frequency of "unsure" responses suggested a lack of confidence in nutrition knowledge. Athletes conveyed a high likelihood that they would use a mobile device application as a nutrition resource, but were more interested in access to nutrition topics than tools such as a food log. We found that college athletes possess minimal sports nutrition knowledge, obtain nutrition information from nonprofessional resources, and were interested in utilizing a mobile device application as a resource. Further research is needed to explore the feasibility and effectiveness of alternative resources, such as a mobile device application, to deliver nutrition information and improve nutrition knowledge.

Structural and electrical properties of conducting diamond nanowires.

PubMed

Sankaran, Kamatchi Jothiramalingam; Lin, Yen-Fu; Jian, Wen-Bin; Chen, Huang-Chin; Panda, Kalpataru; Sundaravel, Balakrishnan; Dong, Chung-Li; Tai, Nyan-Hwa; Lin, I-Nan

2013-02-01

Conducting diamond nanowires (DNWs) films have been synthesized by N₂-based microwave plasma enhanced chemical vapor deposition. The incorporation of nitrogen into DNWs films is examined by C 1s X-ray photoemission spectroscopy and morphology of DNWs is discerned using field-emission scanning electron microscopy and transmission electron microscopy (TEM). The electron diffraction pattern, the visible-Raman spectroscopy, and the near-edge X-ray absorption fine structure spectroscopy display the coexistence of sp³ diamond and sp² graphitic phases in DNWs films. In addition, the microstructure investigation, carried out by high-resolution TEM with Fourier transformed pattern, indicates diamond grains and graphitic grain boundaries on surface of DNWs. The same result is confirmed by scanning tunneling microscopy and scanning tunneling spectroscopy (STS). Furthermore, the STS spectra of current-voltage curves discover a high tunneling current at the position near the graphitic grain boundaries. These highly conducting regimes of grain boundaries form effective electron paths and its transport mechanism is explained by the three-dimensional (3D) Mott's variable range hopping in a wide temperature from 300 to 20 K. Interestingly, this specific feature of high conducting grain boundaries of DNWs demonstrates a high efficiency in field emission and pave a way to the next generation of high-definition flat panel displays or plasma devices.

Metal-Organic Coordination Polymer to Prepare Density Controllable and High Nitrogen-Doped Content Carbon/Graphene for High Performance Supercapacitors.

PubMed

Luo, Jinwei; Zhong, Wenbin; Zou, Yubo; Xiong, Changlun; Yang, Wantai

2017-01-11

Design and preparation of carbon-based electrode material with high nitrogen-doping ratio and appropriate density attract much interest for supercapacitors in practical application. Herein, three porous carbon/graphene (NCG Cu , NCG Fe , and NCG Zn ) with high doping ratio of nitrogen have been prepared via directly pyrolysis of graphene oxide (GO)/metal-organic coordination polymer (MOCP) composites, which were formed by reacting 4,4'-bipyridine (BPD) with CuCl 2 , FeCl 3 , and ZnCl 2 , respectively. As-prepared NCG Cu , NCG Fe and NCG Zn showed high nitrogen doping ratio of 10.68, 12.99, and 11.21 at. %; and high density of 1.52, 0.84, and 1.15 g cm -3 , respectively. When as-prepared samples were used as supercapacitor electrodes, NCG Cu , NCG Fe and NCG Zn exhibited high gravimetric specific capacitances of 369, 298.5, 309.5 F g -1 , corresponding to high volumetric specific capacitances of 560.9, 250.7, 355.9 F cm -3 at a current density of 0.5 A g -1 , as well as good cycling stability, nearly 100% of the capacitance retained after 1000 cycles even at a large current density of 10 A g -1 . It is expected that the provided novel strategy can be used to develop electrode materials in high performance energy conversion/storage devices.

Current Events and the International Relations Curriculum: Instructional Strategies.

ERIC Educational Resources Information Center

Chernotsky, Harry I.

One of the most significant challenges confronting college instructors who teach international politics survey courses is the coverage of current events issues and how to stimulate student interest about the issues. This paper describes two techniques, a current events sweepstakes and a Great Decisions roundtable, designed to infuse current events…

Financial and non-financial conflicts of interests in psychiatry.

PubMed

Maj, Mario

2010-11-01

A conflict of interests occurs when a doctor is unduly influenced by a secondary interest (i.e., a personal incentive) in his acts concerning one of the primary interests to which he is professionally committed (the welfare of patients, the progress of science, or the education of students or residents). One specific variety of conflicts of interests has monopolized the attention of the scientific and lay press: the financial conflicts of interests arising from the relationships between doctors and drug companies. A large literature has described the many, sometimes subtle, ways by which a psychiatrist can be influenced in his prescribing habits or research activities by his relationships with the industry. Some empirical evidence is now available in this area. On the other hand, it has been pointed out that the current debate on this issue is sometimes "affectively charged" or fails to take into account that the interests of patients, families and mental health professionals and those of the industry may be often convergent. Other types of conflicts of interests are beginning now to be discussed. There is evidence that the allegiance of a researcher to a given school of thought may influence the results of studies comparing different psychotherapeutic techniques, thus colliding with the primary interest represented by the progress of science. Political commitment is also emerging as a source of conflicts of interests. Financial and non-financial conflicts of interests are widespread in psychiatric practice and research. They cannot be eradicated, but must be managed more effectively than is currently the case.

Safeguarding children in dentistry: 1. Child protection training, experience and practice of dental professionals with an interest in paediatric dentistry.

PubMed

Harris, J C; Elcock, C; Sidebotham, P D; Welbury, R R

2009-04-25

Following several highly publicised inquiries into the deaths of children from abuse and neglect, there has been much recent interest in the role and responsibility of all health professionals to protect children at risk of maltreatment. The findings of a postal questionnaire, sent in March 2005 to 789 dentists and dental care professionals with an interest in paediatric dentistry working in varied settings in the UK, are presented in a two-part report and discussed in the context of current multi-agency good practice in safeguarding and promoting the welfare of children. This first part explores reported child protection training, experience and practice. There was a significant gap between recognising signs of abuse and responding effectively: 67% of respondents had suspected abuse or neglect of a child patient at some time in their career but only 29% had ever made a child protection referral. The dental profession is alerted to the need to ensure necessary appropriate action to safeguard children is always taken when child abuse or neglect are suspected.