Far-field environment working group summary
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pearcy, E.C.
1995-09-01
This article is a summary of the proceedings of a group discussion which took place at the Workshop on the Role of Natural Analogs in Geologic Disposal of High-Level Nuclear Waste in San Antonio, Texas on July 22-25, 1991. The working group concentrated on the subject of the potential impacts of underground disposal of high-level radioactive wastes on the far-field environment.
Volcanism/tectonics working group summary
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kovach, L.A.
1995-09-01
This article is a summary of the proceedings of a group discussion which took place at the Workshop on the Role of Natural Analogs in Geologic Disposal of High-Level Nuclear Waste in San Antonio, Texas on July 22-25, 1991. The working group concentrated on the subject of the impacts of earthquakes, fault rupture, and volcanic eruption on the underground repository disposal of high-level radioactive wastes. The tectonics and seismic history of the Yucca Mountain site in Nevada is discussed and geologic analogs to that site are described.
Near-field environment/processes working group summary
DOE Office of Scientific and Technical Information (OSTI.GOV)
Murphy, W.M.
1995-09-01
This article is a summary of the proceedings of a group discussion which took place at the Workshop on the Role of Natural Analogs in Geologic Disposal of High-Level Nuclear Waste in San Antonio, Texas on July 22-25, 1991. The working group concentrated on the subject of the near-field environment to geologic repositories for high-level nuclear waste. The near-field environment may be affected by thermal perturbations from the waste, and by disturbances caused by the introduction of exotic materials during construction of the repository. This group also discussed the application of modelling of performance-related processes.
High-level radioactive waste management alternatives
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1974-05-01
A summary of a comprehensive overview study of potential alternatives for long-term management of high-level radioactive waste is presented. The concepts studied included disposal in geologic formations, disposal in seabeds, disposal in ice caps, disposal into space, and elimination by transmutation. (TFD)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1977-06-01
The pilot plant is developed for ERDA low-level contact-handled transuranic waste, ERDA remote-handled intermediate-level transuranic waste, and for high-level waste experiments. All wastes placed in the WIPP arrive at the site processed and packaged; no waste processing is done at the WIPP. All wastes placed into the WIPP are retrievable. The proposed site for WIPP lies 26 miles east of Carlsbad, New Mexico. This document includes the executive summary and a detailed description of the facilities and systems. (DLC)
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Virgin Islands
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Virgin Islands
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. New Jersey
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Missouri
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Rhode Island
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Texas
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Nevada
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Georgia
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Arkansas
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Illinois
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Virginia
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Hawaii
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Minnesota
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Alaska
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Delaware
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Utah
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Iowa
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Kentucky
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Florida
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Delaware
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Indiana
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Utah
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Mississippi
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Vermont
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Georgia
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. New Mexico
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Alabama
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Connecticut
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Florida
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Illinois
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Pennsylvania
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Colorado
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Arkansas
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. California
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. South Dakota
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Louisiana
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Wyoming
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Hawaii
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Massachusetts
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Nevada
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Connecticut
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Michigan
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. New Jersey
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Ohio
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Washington
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Alabama
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. North Carolina
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Minnesota
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Arizona
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Arizona
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Maryland
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Indiana
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Michigan
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. North Carolina
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Iowa
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Washington
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Montana
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Texas
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Kansas
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Idaho
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Maryland
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Ohio
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Montana
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Colorado
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Wyoming
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Oregon
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Pennsylvania
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Oregon
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Virginia
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Wisconsin
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Nebraska
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Vermont
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Puerto Rico
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Wisconsin
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. North Dakota
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. New York
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. New Hampshire
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. California
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Maine
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Oklahoma
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Maine
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. South Carolina
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Missouri
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Massachusetts
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Alaska
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. North Dakota
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Kansas
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Kentucky
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Tennessee
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Oklahoma
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. New Mexico
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Louisiana
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. West Virginia
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Tennessee
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Idaho
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. Nebraska
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. Mississippi
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
78 FR 14840 - U.S.-EU High Level Regulatory Cooperation Forum-Stakeholder Session
Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-07
... OFFICE OF MANAGEMENT AND BUDGET U.S.-EU High Level Regulatory Cooperation Forum--Stakeholder Session AGENCY: Office of Management and Budget. ACTION: Notice of Public Meeting. SUMMARY: On September... and Budget (OMB), together with the European Commission's Enterprise and Trade Directorates-General...
PSAT/NMSQT[R] 2014-2015 College-Bound High School Sophomores. Summary Report. District of Columbia
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
PSAT/NMSQT[R] 2014-2015 College-Bound High School Juniors. Summary Report. District of Columbia
ERIC Educational Resources Information Center
College Board, 2015
2015-01-01
In the fall of 2014, students took the Preliminary SAT/National Merit Scholarship Qualifying Test (PSAT/NMSQT) to help determine their level of readiness for college. The PSAT/NMSQT 2014 State Summary Reports summarize the characteristics, scores and educational plans of the Class of 2016 and Class of 2017.
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-04
... DEPARTMENT OF ENERGY Amended Record of Decision: Idaho High-Level Waste and Facilities Disposition Final Environmental Impact Statement Revised by State 12/ 21/09 AGENCY: Department of Energy. ACTION: Amended Record of Decision. SUMMARY: The U.S. Department of Energy (DOE) is amending its initial Record of...
ERIC Educational Resources Information Center
Mok, Wilson Shun; Chan, Winnie Wai
2016-01-01
Testing has been found to facilitate students' long-term retention of information. However, the learning performance of highly test-anxious students can be impaired by tests. Thus, these students may learn ineffectively in a testing context. By contrast, summary writing may not trigger test anxiety and is therefore another learning strategy to…
Neary, W J; Hillier, V F; Flute, T; Stephens, S D G; Ramsden, R T; Evans, D G R
2010-08-01
To investigate the relationship between those issues concerning quality of life in patients with neurofibromatosis type 2 (NF2) as identified by the closed set NF2 questionnaire and the eight norm-based measures and the physical component summary (PCS) and mental component summary (MCS) scores of the Short Form-36 (SF-36) Questionnaire. Postal questionnaire study. Questionnaires sent to subjects' home addresses. Eighty-seven adult subjects under the care of the Manchester Multidisciplinary NF2 Clinic were invited to participate. Sixty-two (71%) completed sets of closed set NF2 questionnaires and SF-36 questionnaires were returned. Subjects with NF2 scored less than the norm of 50 on both the physical component summary and mental component summary scores and the eight individual norm-based measures of the Short Form-36 questionnaire. Correlations (using Kendall's tau) were examined between patients' perceptions of their severity of difficulty with the following activities and the eight norm-based measures and the physical component summary and mental component summary scores of the Short Form-36 questionnaire: Communicating with spouse/significant other (N = 61). The correlation coefficients were significant at the 0.01 level for the mental component summary score, together with three of the norm-based scores [vitality (VT), social functioning and role emotional]. Social communication (N = 62). All 10 correlations were significant at the 0.01 or 0.001 level. Balance (N = 59). All 10 correlations were highly significant at the P < 0.001 level. Hearing difficulties (N = 61). All correlations were significant at either the 0.01 level or less apart from the mental component summary score and three of the norm-based scores (role physical, VT and mental health). Mood change (N = 61). All correlations were significant at the 0.01 level or less, apart from one norm-based score (role physical). The Short Form-36 questionnaire has allowed us to relate patients' perceptions of their difficulties, as identified by the closed set NF2 questionnaire, to the physical and mental domains measured by this validated and widely used scale, and has provided further insight into areas of functioning affected by NF2.
Zheng, Jie; Rodriguez, Santiago; Laurin, Charles; Baird, Denis; Trela-Larsen, Lea; Erzurumluoglu, Mesut A; Zheng, Yi; White, Jon; Giambartolomei, Claudia; Zabaneh, Delilah; Morris, Richard; Kumari, Meena; Casas, Juan P; Hingorani, Aroon D; Evans, David M; Gaunt, Tom R; Day, Ian N M
2017-01-01
Fine mapping is a widely used approach for identifying the causal variant(s) at disease-associated loci. Standard methods (e.g. multiple regression) require individual level genotypes. Recent fine mapping methods using summary-level data require the pairwise correlation coefficients ([Formula: see text]) of the variants. However, haplotypes rather than pairwise [Formula: see text], are the true biological representation of linkage disequilibrium (LD) among multiple loci. In this article, we present an empirical iterative method, HAPlotype Regional Association analysis Program (HAPRAP), that enables fine mapping using summary statistics and haplotype information from an individual-level reference panel. Simulations with individual-level genotypes show that the results of HAPRAP and multiple regression are highly consistent. In simulation with summary-level data, we demonstrate that HAPRAP is less sensitive to poor LD estimates. In a parametric simulation using Genetic Investigation of ANthropometric Traits height data, HAPRAP performs well with a small training sample size (N < 2000) while other methods become suboptimal. Moreover, HAPRAP's performance is not affected substantially by single nucleotide polymorphisms (SNPs) with low minor allele frequencies. We applied the method to existing quantitative trait and binary outcome meta-analyses (human height, QTc interval and gallbladder disease); all previous reported association signals were replicated and two additional variants were independently associated with human height. Due to the growing availability of summary level data, the value of HAPRAP is likely to increase markedly for future analyses (e.g. functional prediction and identification of instruments for Mendelian randomization). The HAPRAP package and documentation are available at http://apps.biocompute.org.uk/haprap/ CONTACT: : jie.zheng@bristol.ac.uk or tom.gaunt@bristol.ac.ukSupplementary information: Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
The Work Breakdown Structure (WBS) Book begins with this Overview section, which contains the high-level summary cost estimate, the cost profile, and the global construction schedule. The summary cost estimate shows the total US cost and the cost in terms of PHENIX construction funds for building the PHENIX detector. All costs in the WBS book are shown in FY 1993 dollars. Also shown are the institutional and foreign contributions, the level of pre-operations funding, and the cost of deferred items. Pie charts are presented at PHENIX WBS level 1 and 2 that show this information. The PHENIX construction funds aremore » shown broken down to PHENIX WBS level 3 items per fiscal year, and the resulting profile is compared to the RHIC target profile. An accumulated difference of the two profiles is also shown. The PHENIX global construction schedule is presented at the end of the Overview section. Following the Overview are sections for each subsystem. Each subsystem section begins with a summary cost estimate, cost profile, and critical path. The total level 3 cost is broken down into fixed costs (M&S), engineering costs (EDIA) and labor costs. Costs are further broken down in terms of PHENIX construction funds, institutional and foreign contributions, pre-operations funding, and deferred items. Also shown is the contingency at level 3 and the level 4 breakdown of the total cost. The cost profile in fiscal years is shown at level 3. The subsystem summaries are followed by the full cost estimate and schedule sheets for that subsystem. These detailed sheets are typically carried down to level 7 or 8. The cost estimate Total, M&S, EDIA, and Labor breakdowns, as well as contingency, for each WBS entry.« less
PHENIX Work Breakdown Structure. Cost and schedule review copy
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1994-02-01
The Work Breakdown Structure (WBS) Book begins with this Overview section, which contains the high-level summary cost estimate, the cost profile, and the global construction schedule. The summary cost estimate shows the total US cost and the cost in terms of PHENIX construction funds for building the PHENIX detector. All costs in the WBS book are shown in FY 1993 dollars. Also shown are the institutional and foreign contributions, the level of pre-operations funding, and the cost of deferred items. Pie charts are presented at PHENIX WBS level 1 and 2 that show this information. The PHENIX construction funds aremore » shown broken down to PHENIX WBS level 3 items per fiscal year, and the resulting profile is compared to the RHIC target profile. An accumulated difference of the two profiles is also shown. The PHENIX global construction schedule is presented at the end of the Overview section. Following the Overview are sections for each subsystem. Each subsystem section begins with a summary cost estimate, cost profile, and critical path. The total level 3 cost is broken down into fixed costs (M&S), engineering costs (EDIA) and labor costs. Costs are further broken down in terms of PHENIX construction funds, institutional and foreign contributions, pre-operations funding, and deferred items. Also shown is the contingency at level 3 and the level 4 breakdown of the total cost. The cost profile in fiscal years is shown at level 3. The subsystem summaries are followed by the full cost estimate and schedule sheets for that subsystem. These detailed sheets are typically carried down to level 7 or 8. The cost estimate shows Total, M&S, EDIA, and Labor breakdowns, as well as contingency, for each WBS entry.« less
Waste forms, packages, and seals working group summary
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sridhar, N.
1995-09-01
This article is a summary of the proceedings of a group discussion which took place at the Workshop on the Role of Natural Analogs in Geologic Disposal of High-Level Nuclear Waste in San Antonio, Texas on July 22-25, 1991. The working group concentrated on the subject of radioactive waste forms and packaging. Also included is a description of the use of natural analogs in waste packaging, container materials and waste forms.
La Torre, Giuseppe; Sestili, Cristina; Mannocci, Alice; Sinopoli, Alessandra; De Paolis, Massimiliano; De Francesco, Sara; Rapaccini, Laura; Barone, Marco; Iodice, Valentina; Lojodice, Bruno; Sernia, Sabina; De Sio, Simone; Del Cimmuto, Angela; De Giusti, Maria
2018-01-19
The aim of this work is investigate relationship between health-related quality of life and work-related stress and the impact of gender, education level, and age on this relationship. A cross-sectional study was conducted among workers of various setting in Rome and Frosinone. Work-related stress was measured with a demand-control questionnaire and health-related functioning by SF (short form)-12 health survey. There were 611 participants. Men reported high mental composite summary (MCS) and physical composite summary (PCS). In multivariate analysis age, gender ( p < 0.001) and job demand (0.045) predicted low PCS. Low MCS predicted poor PCS. Job demand and educational level resulted negatively associated with MCS. In an analysis stratified for age, gender, and educational level, gender and age resulted effect modifier for MCS, gender and education level for PCS. In women increase of decision latitude predict ( p = 0.001) an increase in MCS; a low job demand predict high MCS in male ( p ≤ 0.001). In younger workers, a lower level of job demand predicted high MCS (<0.001). For PCS, gender and education level resulted effect modifier. In women, high decision latitude predicted higher PCS ( p = 0.001) and lower level of job demand results in higher PCS ( p ≤ 0.001). Higher educational level resulted predictor of low PCS. Management of risk about work-related stress should consider socio-demographic factors.
Summary of the COS Cycle 22 Calibration Program
NASA Astrophysics Data System (ADS)
Sonnentrucker, Paule; Becker, George; Bostroem, Azalee; Debes, John H.; Ely, Justin; Fox, Andrew; Lockwood, Sean; Oliveira, Cristina; Penton, Steven; Proffitt, Charles; Roman-Duval, Julia; Sahnow, David; Sana, Hugues; Taylor, Jo; Welty, Alan D.; Wheeler, Thomas
2016-09-01
We summarize the calibration activities for the Cosmic Origins Spectrograph (COS) on the Hubble Space Telescope during Cycle 22 which ran from November 2014 through October 2015. We give an overview of the COS calibration plan, COS usage statistics and we briefly describe major changes with respect to the previous cycle. High-level executive summaries for each calibration program comprising Cycle 22 are also given here. Results of the analysis attached to each program are published in separate ISRs.
DOT National Transportation Integrated Search
2004-09-01
Conventionally, the road centerline surveys have : been performed by the traditional survey methods, : providing rather high, even sub-centimeter level of : accuracy. The major problem, however, that the : Departments of Transportation face, is the s...
FUSE: a profit maximization approach for functional summarization of biological networks.
Seah, Boon-Siew; Bhowmick, Sourav S; Dewey, C Forbes; Yu, Hanry
2012-03-21
The availability of large-scale curated protein interaction datasets has given rise to the opportunity to investigate higher level organization and modularity within the protein interaction network (PPI) using graph theoretic analysis. Despite the recent progress, systems level analysis of PPIS remains a daunting task as it is challenging to make sense out of the deluge of high-dimensional interaction data. Specifically, techniques that automatically abstract and summarize PPIS at multiple resolutions to provide high level views of its functional landscape are still lacking. We present a novel data-driven and generic algorithm called FUSE (Functional Summary Generator) that generates functional maps of a PPI at different levels of organization, from broad process-process level interactions to in-depth complex-complex level interactions, through a pro t maximization approach that exploits Minimum Description Length (MDL) principle to maximize information gain of the summary graph while satisfying the level of detail constraint. We evaluate the performance of FUSE on several real-world PPIS. We also compare FUSE to state-of-the-art graph clustering methods with GO term enrichment by constructing the biological process landscape of the PPIS. Using AD network as our case study, we further demonstrate the ability of FUSE to quickly summarize the network and identify many different processes and complexes that regulate it. Finally, we study the higher-order connectivity of the human PPI. By simultaneously evaluating interaction and annotation data, FUSE abstracts higher-order interaction maps by reducing the details of the underlying PPI to form a functional summary graph of interconnected functional clusters. Our results demonstrate its effectiveness and superiority over state-of-the-art graph clustering methods with GO term enrichment.
El Shayeb, Mohamed; Topfer, Leigh-Ann; Stafinski, Tania; Pawluk, Lawrence; Menon, Devidas
2014-01-01
Background: Greater awareness of sleep-disordered breathing and rising obesity rates have fueled demand for sleep studies. Sleep testing using level 3 portable devices may expedite diagnosis and reduce the costs associated with level 1 in-laboratory polysomnography. We sought to assess the diagnostic accuracy of level 3 testing compared with level 1 testing and to identify the appropriate patient population for each test. Methods: We conducted a systematic review and meta-analysis of comparative studies of level 3 versus level 1 sleep tests in adults with suspected sleep-disordered breathing. We searched 3 research databases and grey literature sources for studies that reported on diagnostic accuracy parameters or disease management after diagnosis. Two reviewers screened the search results, selected potentially relevant studies and extracted data. We used a bivariate mixed-effects binary regression model to estimate summary diagnostic accuracy parameters. Results: We included 59 studies involving a total of 5026 evaluable patients (mostly patients suspected of having obstructive sleep apnea). Of these, 19 studies were included in the meta-analysis. The estimated area under the receiver operating characteristics curve was high, ranging between 0.85 and 0.99 across different levels of disease severity. Summary sensitivity ranged between 0.79 and 0.97, and summary specificity ranged between 0.60 and 0.93 across different apnea–hypopnea cut-offs. We saw no significant difference in the clinical management parameters between patients who underwent either test to receive their diagnosis. Interpretation: Level 3 portable devices showed good diagnostic performance compared with level 1 sleep tests in adult patients with a high pretest probability of moderate to severe obstructive sleep apnea and no unstable comorbidities. For patients suspected of having other types of sleep-disordered breathing or sleep disorders not related to breathing, level 1 testing remains the reference standard. PMID:24218531
Estimating the discharge for ordinary high water levels in Kansas : [technical summary].
DOT National Transportation Integrated Search
2014-09-01
The water resource design community in Kansas, including the Kansas Department : of Transportation (KDOT), is required to obtain appropriate permits for construction : projects. Projects that involve stream modification, including drainage structures...
Summary of the Advanced Reactor Design Criteria (ARDC) Phase 2 Activities
DOE Office of Scientific and Technical Information (OSTI.GOV)
Holbrook, Mark Raymond
This report provides an end-of-year summary reflecting the progress and status of proposed regulatory design criteria for advanced non-LWR designs in accordance with the Level 3 milestone in M3AT-15IN2001017 in work package AT-15IN200101. These criteria have been designated as ARDC, and they provide guidance to future applicants for addressing the GDC that are currently applied specifically to LWR designs. The report provides a summary of Phase 2 activities related to the various tasks associated with ARDC development and the subsequent development of example adaptations of ARDC for Sodium Fast Reactor (SFR) and modular High Temperature Gas-cooled Reactor (HTGR) designs.
Immigration and Its Effect on the College-Going Outcomes of Natives
ERIC Educational Resources Information Center
Neymotin, Florence
2009-01-01
In this paper, I analyze immigration's effect on the SAT-scores and college application patterns of high school students in California and Texas. The student-level dataset used is longitudinal in nature and is matched via a unique algorithm to the Census 2000 summary tabulation files to determine immigration at the local census-place level. The…
Managing travel for planned special events handbook : executive summary
DOT National Transportation Integrated Search
2007-06-01
This report was written to communicate new and proven institutional and high-level operational techniques and strategies for achieving a coordinated, proactive approach to managing travel for all planned special events in a region in addition to faci...
Integrated corridor management modeling results report : Dallas, Minneapolis, and San Diego.
DOT National Transportation Integrated Search
2012-02-01
This executive summary documents the analysis methodologies, tools, and performance measures used to analyze Integrated Corridor Management (ICM) strategies; and presents high-level results for the successful implementation of ICM at three Stage 2 Pi...
Preliminary technical data summary No. 3 for the Defense Waste Processing Facility
DOE Office of Scientific and Technical Information (OSTI.GOV)
Landon, L.F.
1980-05-01
This document presents an update on the best information presently available for the purpose of establishing the basis for the design of a Defense Waste Processing Facility. Objective of this project is to provide a facility to fix the radionuclides present in Savannah River Plant (SRP) high-level liquid waste in a high-integrity form (glass). Flowsheets and material balances reflect the alternate CAB case including the incorporation of low-level supernate in concrete. (DLC)
A comprehensive review of arsenic levels in the semiconductor manufacturing industry.
Park, Donguk; Yang, Haengsun; Jeong, Jeeyeon; Ha, Kwonchul; Choi, Sangjun; Kim, Chinyon; Yoon, Chungsik; Park, Dooyong; Paek, Domyung
2010-11-01
This paper presents a summary of arsenic level statistics from air and wipe samples taken from studies conducted in fabrication operations. The main objectives of this study were not only to describe arsenic measurement data but also, through a literature review, to categorize fabrication workers in accordance with observed arsenic levels. All airborne arsenic measurements reported were included in the summary statistics for analysis of the measurement data. The arithmetic mean was estimated assuming a lognormal distribution from the geometric mean and the geometric standard deviation or the range. In addition, weighted arithmetic means (WAMs) were calculated based on the number of measurements reported for each mean. Analysis of variance (ANOVA) was employed to compare arsenic levels classified according to several categories such as the year, sampling type, location sampled, operation type, and cleaning technique. Nine papers were found reporting airborne arsenic measurement data from maintenance workers or maintenance areas in semiconductor chip-making plants. A total of 40 statistical summaries from seven articles were identified that represented a total of 423 airborne arsenic measurements. Arsenic exposure levels taken during normal operating activities in implantation operations (WAM = 1.6 μg m⁻³, no. of samples = 77, no. of statistical summaries = 2) were found to be lower than exposure levels of engineers who were involved in maintenance works (7.7 μg m⁻³, no. of samples = 181, no. of statistical summaries = 19). The highest level (WAM = 218.6 μg m⁻³) was associated with various maintenance works performed inside an ion implantation chamber. ANOVA revealed no significant differences in the WAM arsenic levels among the categorizations based on operation and sampling characteristics. Arsenic levels (56.4 μg m⁻³) recorded during maintenance works performed in dry conditions were found to be much higher than those from maintenance works in wet conditions (0.6 μg m⁻³). Arsenic levels from wipe samples in process areas after maintenance activities ranged from non-detectable to 146 μg cm⁻², indicating the potential for dispersion into the air and hence inhalation. We conclude that workers who are regularly or occasionally involved in maintenance work have higher potential for occupational exposure than other employees who are in charge of routine production work. In addition, fabrication workers can be classified into two groups based on the reviewed arsenic exposure levels: operators with potential for low levels of exposure and maintenance engineers with high levels of exposure. These classifications could be used as a basis for a qualitative ordinal ranking of exposure in an epidemiological study.
ERIC Educational Resources Information Center
Ward, Mary; Wolff, Warren
A study determined labor market needs of high technology firms in Colorado. It assessed such needs in relation to present and projected output of vocational education and training programs and developed recommendations for policies and programs to meet industry training needs at the vocational training level. Data were collected through on-site…
ERIC Educational Resources Information Center
Lee, Chungmei
2004-01-01
This report takes a look at the issues concerning racial segregation and educational outcomes in Metropolitan Boston. Despite the fact that metro Boston is overwhelmingly white, its public schools are highly segregated by race and language. Segregated minority schools in metro Boston are profoundly unequal, with high poverty levels, with lower…
ERIC Educational Resources Information Center
Estacion, Angela; Cotner, Bridget A.; D'Souza, Stephanie; Smith, Chrystal A. S.; Borman, Kathryn M.
2011-01-01
This study of advanced-level high school courses that offer credit toward both a high school diploma and a college degree in Florida compares one such program (dual enrollment) with others, describing the number and characteristics of grade 11 and 12 students enrolled overall and by district. It also examines dual enrollment partnerships between…
The association of soda sales tax and school nutrition laws: a concordance of policies.
Greathouse, K Leigh; Chriqui, Jamie; Moser, Richard P; Agurs-Collins, Tanya; Perna, Frank M
2014-10-01
The current research examined the association between state disfavoured tax on soda (i.e. the difference between soda sales tax and the tax on food products generally) and a summary score representing the strength of state laws governing competitive beverages (beverages that compete with the beverages in the federally funded school lunch programme) in US schools. The Classification of Laws Associated with School Students (CLASS) summary score reflected the strength of a state's laws restricting competitive beverages sold in school stores, vending machines, school fundraisers and à la carte cafeteria items. Bridging the Gap (BTG) is a nationally recognized research initiative that provided state-level soda tax data. The main study outcome was the states' competitive beverage summary scores for elementary, middle and high school grade levels, as predicted by the states' disfavoured soda tax. Univariate and multivariate analyses were conducted, adjusting for year and state. Data from BTG and CLASS were used. BTG and CLASS data from all fifty states and the District of Columbia from 2003 to 2010 were used. A higher disfavoured soda sales tax was generally associated with an increased likelihood of having strong school beverage laws across grade levels, and especially when disfavoured soda sales tax was >5 %. These data suggest a concordance between states' soda taxes and laws governing beverages sold in schools. States with high disfavoured sales tax on soda had stronger competitive beverage laws, indicating that the state sales tax environment may be associated with laws governing beverage policy in schools.
DOT National Transportation Integrated Search
2015-08-01
In post-tensioning construction, steel cables : running through PVC pipes buried in concrete : construction components are subjected to a high : level of tension and then secured. This gives the : component significant strength, allowing bridge : spa...
DOT National Transportation Integrated Search
2008-01-01
Reliable predictions of the seasonal high : groundwater table (SHGWT) at potential : construction sites are critical for roadway : designs. Maximum SHGWT levels can affect the : construction and maintenance of roads, and : the design and operation of...
Surplus Highly Enriched Uranium Disposition Program plan
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1996-10-01
The purpose of this document is to provide upper level guidance for the program that will downblend surplus highly enriched uranium for use as commercial nuclear reactor fuel or low-level radioactive waste. The intent of this document is to outline the overall mission and program objectives. The document is also intended to provide a general basis for integration of disposition efforts among all applicable sites. This plan provides background information, establishes the scope of disposition activities, provides an approach to the mission and objectives, identifies programmatic assumptions, defines major roles, provides summary level schedules and milestones, and addresses budget requirements.
Westenburg, C.L.; La Camera, R. J.
1996-01-01
The U.S. Geological Survey, in support of the U.S. Department of Energy, Yucca Mountain Site Characterization Project, collects, compiles, and summarizes hydrologic data in the Yucca Mountain region. The data are collected to allow assessments of ground-water resources during studies to determine the potential suitability of Yucca Mountain for storing high-level nuclear waste. Data on ground-water levels at 36 sites, ground-water discharge at 6 sites, and ground-water withdrawals within Crater Flat, Jackass Flats, Mercury Valley, and the Amargosa Desert are presented for calendar year 1994. Data collected prior to 1994 are graphically presented and data collected by other agencies (or as part of other programs) are included to further indicate variations of ground-water levels, discharges, and withdrawals through time. A statistical summary of ground-water levels at seven wells in Jackass Flats is presented. The statistical summary includes the number of measurements, the maximum, minimum, and median water-level altitudes, and the average deviation of measured water-level altitudes for selected baseline periods and for calendar years 1992-94.
NASA Technical Reports Server (NTRS)
Murri, Daniel G.; Shah, Gautam H.; Dicarlo, Daniel J.
1994-01-01
As part of the NASA High-Angle-of-Attack Technology Program (HATP), flight tests are currently being conducted with a multi-axis thrust vectoring system applied to the NASA F-18 High Alpha Research Vehicle (HARV). A follow-on series of flight tests with the NASA F-18 HARV will be focusing on the application of actuated forebody strake controls. These controls are designed to provide increased levels of yaw control at high angles of attack where conventional aerodynamic controls become ineffective. The series of flight tests are collectively referred to as the Actuated Nose Strakes for Enhanced Rolling (ANSER) Flight Experiment. The development of actuated forebody strake controls for the F-18 HARV is discussed and a summary of the ground tests conducted in support of the flight experiment is provided. A summary of the preparations for the flight tests is also provided.
NASA Technical Reports Server (NTRS)
Hamilton, William T; Nelson, Warren H
1947-01-01
A summary of the results of wind-tunnel tests to determine the high-speed aerodynamic characteristics of six model wings having NACA 65sub1-series sections is presented in this report. The 8-percent-thick wings were superior to the 10-percent and 12-percent-thick wings from the standpoint of power economy during level flight for Mach numbers above 0.76. However, airplanes that are to fly at Mach numbers below 0.76 will gain aerodynamically if the percentage thickness of the wing and the aspect ratio are both increased. The lift-curve slopes for the 8-percent-thick wings at 0.85 Mach number were roughly twice their low-speed values.
ERIC Educational Resources Information Center
Uriarte, Miren; Karp, Faye; Gagnon, Laurie; Tung, Rosann; Rustan, Sarah; Chen, Jie; Berardino, Michael; Stazesky, Pamela
2011-01-01
English language learners (ELLs), their teachers, and the schools and programs where they are enrolled face a triple challenge: (1) students must be taught and learn English at a level of proficiency high enough to allow them access to academic content; (2) students must be taught and learn academic content at a level comparable to that of English…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kovach, L.A.; Murphy, W.M.
1995-09-01
A Workshop on the Role of Natural Analogs in Geologic Disposal of High-Level Nuclear Waste was held in San Antonio, Texas on July 22--25, 1991. The proceedings comprise seventeen papers submitted by participants at the workshop. A series of papers addresses the relation of natural analog studies to the regulation, performance assessment, and licensing of a geologic repository. Applications of reasoning by analogy are illustrated in papers on the role of natural analogs in studies of earthquakes, petroleum, and mineral exploration. A summary is provided of a recently completed, internationally coordinated natural analog study at Pocos de Caldas, Brazil. Papersmore » also cover problems and applications of natural analog studies in four technical areas of nuclear waste management-. waste form and waste package, near-field processes and environment, far-field processes and environment, and volcanism and tectonics. Summaries of working group deliberations in these four technical areas provide reviews and proposals for natural analog applications. Individual papers have been cataloged separately.« less
ERIC Educational Resources Information Center
National Institutes of Health (DHEW), Bethesda, MD. High Blood Pressure Information Center.
As part of the National High Blood Pressure Education Program effort, the conference explored the implications and impact of the prevalence of hypertension in Spanish-speaking populations in California. Approximately 150 experts in health fields, representing all levels of government, public and private health care providers, consumers, and health…
ERIC Educational Resources Information Center
Hatch, Kathlyn; Engels, Nancy
This report describes a 3-year project which used local architecture as a resource for teaching the arts and humanities at the secondary level. The project involved 24 Massachusetts high school teachers in art, social studies, industrial arts, and the language arts working with project staff. The teachers attended two week-long summer courses.…
Yemm, Rowan; Bhattacharya, Debi; Wright, David; Poland, Fiona
2014-07-05
This study aimed to identify any differences in opinion between UK hospital junior doctors and community General Practitioners (GPs) with respect to the ideal content and characteristics of discharge summaries, and to explore junior doctors' training for and awareness of post-discharge requirements of GPs. A piloted anonymous survey was posted to 74 junior doctors at a UK general hospital and 153 local GPs. Doctors were asked to rank discharge summary key content and characteristics in order of importance. GP discharge summary preferences and junior doctor training were also investigated. Non-respondents, identified by non-receipt of a separate participation card, were followed up once. Thirty-six (49%) junior doctors and 42 (28%) GPs returned completed questionnaires. Accuracy was a priority with 24 (72%) GPs and 28 (88%) junior doctors ranking it most important. Details of medication changes were considered most important by 13 (39%) GPs and 4 (12%) junior doctors. Inadequate training in discharge summary writing was reported by 13 (36%) junior doctors. Although based on small sample sizes from one location, the level and range of differences in perceived importance of reporting medication changes suggests that many discharge summaries may not currently fulfil GP requirements for managing continuity of care. Results indicate that over a third of junior doctors felt inadequately prepared for writing discharge summaries. There may therefore be both a need and professional support for further training in discharge summary writing, requiring confirmatory research.
Facilitating the Information Exchange Using a Modular Electronic Discharge Summary.
Denecke, Kerstin; Dittli, Pascal A; Kanagarasa, Niveadha; Nüssli, Stephan
2018-01-01
Discharge summaries are a standard communication tool delivering important clinical information from inpatient to ambulatory care. To ensure a high quality, correctness and completeness, the generation process is time consuming. It requires also contributions of multiple persons. This is problematic since the primary care provider needs the information from the discharge summary for continuing the intended treatment. To address this challenge, we developed a concept for exchanging a modular electronic discharge summary. Through a literature review and interviews with multiple stakeholders, we analysed existing processes and derived requirements for an improved communication of the discharge summary. In this paper, we suggest a concept of a modular electronic discharge summary that is exchanged through the electronic patient dossier in CDA CH level 2 documents. Until 2020, all Swiss hospitals are obliged to connect to the electronic patient dossier. Our concept allows to access already completed modules of the discharge summary from the primary care side, before the entire report is entirely finalised. The data is automatically merged with the local patient record on the physician side and prepared for data integration into the practice information system. Our concept offers the opportunity not only to improve the information exchange between hospital and primary care, but it also provides a potential use case and demonstrates a benefit of the electronic patient dossier for primary care providers who are so far not obliged to connect to the patient dossier in Switzerland.
This report is the second edition of the U.S. Environmental Protection Agency's (US EPA's) 2005 report and provides a high level summary of information on the applicability of existing and emerging noncombustion technologies for the remediation of...
Ames Infusion Stories for NASA Annual Technology Report
NASA Technical Reports Server (NTRS)
Smith, Brandon; Jan, Darrell Leslie; Venkatapathy, Ethiraj
2015-01-01
These are short (2-page) high-level summaries of technologies that have been infused - i.e., taken the next level. For example, 3DMAT started off as a Center Innovation Fund (CIF) project and graduated to the Game-changing Program (GCD), where it is being prepared for use in Orion. The Nano Entry System similarly started as CIF and graduated to GCD. The High Tortuosity Carbon Dioxide Conversion Device also started off as CIF and then received an award for further development from the NASA Innovative Advanced Concepts program (NIAC).
QUANTIFYING ALTERNATIVE SPLICING FROM PAIRED-END RNA-SEQUENCING DATA.
Rossell, David; Stephan-Otto Attolini, Camille; Kroiss, Manuel; Stöcker, Almond
2014-03-01
RNA-sequencing has revolutionized biomedical research and, in particular, our ability to study gene alternative splicing. The problem has important implications for human health, as alternative splicing may be involved in malfunctions at the cellular level and multiple diseases. However, the high-dimensional nature of the data and the existence of experimental biases pose serious data analysis challenges. We find that the standard data summaries used to study alternative splicing are severely limited, as they ignore a substantial amount of valuable information. Current data analysis methods are based on such summaries and are hence sub-optimal. Further, they have limited flexibility in accounting for technical biases. We propose novel data summaries and a Bayesian modeling framework that overcome these limitations and determine biases in a non-parametric, highly flexible manner. These summaries adapt naturally to the rapid improvements in sequencing technology. We provide efficient point estimates and uncertainty assessments. The approach allows to study alternative splicing patterns for individual samples and can also be the basis for downstream analyses. We found a several fold improvement in estimation mean square error compared popular approaches in simulations, and substantially higher consistency between replicates in experimental data. Our findings indicate the need for adjusting the routine summarization and analysis of alternative splicing RNA-seq studies. We provide a software implementation in the R package casper.
Code of Federal Regulations, 2011 CFR
2011-01-01
... competitive levels within the pay band, including (as appropriate) any applicable locality payment authorized... and forth daily to their usual employment. Modal rating is the summary rating level assigned most frequently among the actual ratings of record that are: (1) Assigned under the summary level pattern that...
Manpower Education in a Growing Economy.
ERIC Educational Resources Information Center
Darcy, Robert L.; Powell, Phillip E.
This publication provides an introduction to manpower education and presents a summary report on a 2-year res"arch and curriculum development project for manpower and economic education at the junior high school level. The introduction includes "The Meaning of Manpower Education" and "Major Themes for A Manpower Education Course" which outlines…
The AFS Volunteer Resources Study: Summary of Findings from Australia.
ERIC Educational Resources Information Center
Walsh, Desmond; And Others
The American Field Service (AFS) has 3,500 volunteers throughout Australia. Local chapters recruit potential host families and participants. Host families are recruited actively and selectively while volunteers are recruited largely through AFS presentations at schools, through friends, and by returning volunteers. Due to a high level of demand…
NASA Technical Reports Server (NTRS)
Schomer, Donald F.
1997-01-01
The document includes an executive summary of the program activities; questions regarding tiling that have yet to be addressed; and the impact of the grants received which include MDACC Infrastructure development, support of technology transfer, and the technical accomplishments of the program.
Correspondence Study; A Summary Review of the Research and Development Literature.
ERIC Educational Resources Information Center
Mathieson, David E.
Beginning with a historical review of private correspondence schools, supervised high school level programs, military programs (notable the United States Armed Forces Institute), and activities by such university extension luminaries as William Rainey Harper and W. H. Lighty, this literature review covers accreditation and licensing problems,…
Degarege, Abraham; Degarege, Dawit; Veledar, Emir; Erko, Berhanu; Nacher, Mathieu; Beck-Sague, Consuelo M.; Madhivanan, Purnima
2016-01-01
Background It has been suggested that Schistosoma infection may be associated with Plasmodium falciparum infection or related reduction in haemoglobin level, but the nature of this interaction remains unclear. This systematic review synthesized evidence on the relationship of S. haematobium or S. mansoni infection with the occurrence of P. falciparum malaria, Plasmodium density and related reduction in haemoglobin level among children in sub-Saharan Africa (SSA). Methodology/Principal findings A systematic review in according with PRISMA guidelines was conducted. All published articles available in PubMed, Embase, Cochrane library and CINAHL databases before May 20, 2015 were searched without any limits. Two reviewers independently screened, reviewed and assessed all the studies. Cochrane Q and Moran’s I2 were used to assess heterogeneity and the Egger test was used to examine publication bias. The summary odds ratio (OR), summary regression co-efficient (β) and 95% confidence intervals (CI) were estimated using a random-effects model. Out of 2,920 citations screened, 12 articles (five cross-sectional, seven prospective cohort) were eligible to be included in the systematic review and 11 in the meta-analysis. The 12 studies involved 9,337 children in eight SSA countries. Eight studies compared the odds of asymptomatic/uncomplicated P. falciparum infection, two studies compared the incidence of uncomplicated P. falciparum infection, six studies compared P. falciparum density and four studies compared mean haemoglobin level between children infected and uninfected with S. haematobium or S. mansoni. Summary estimates of the eight studies based on 6,018 children showed a higher odds of asymptomatic/uncomplicated P. falciparum infection in children infected with S. mansoni or S. haematobium compared to those uninfected with Schistosoma (summary OR: 1.82; 95%CI: 1.41, 2.35; I2: 52.3%). The increase in odds of asymptomatic/uncomplicated P. falciparum infection among children infected with Schistosoma remained significant when subgroup analysis was conducted for S. haematobium (summary OR: 1.68; 95%CI: 1.18, 2.41; I2: 53.2%) and S. mansoni (summary OR: 2.15; 95%CI: 1.89, 2.46: I2: 0.0%) infection. However, the density of P. falciparum infection was lower in children co-infected with S. haematobium compared to those uninfected with Schistosoma (summary-β: -0.14; 95% CI: -0.24, -0.01; I2: 39.7%). The mean haemoglobin level was higher among children co-infected with S. haematobium and P. falciparum than those infected with only P. falciparum (summary-mean haemoglobin difference: 0.49; 95% CI: 0.04, 0.95; I2: 66.4%) Conclusions/Significance The current review suggests S. mansoni or S. haematobium co-infection may be associated with increased prevalence of asymptomatic/uncomplicated P. falciparum infection in children, but may protect against high density P. falciparum infection and related reduction in haemoglobin level. PMID:27926919
DOE Office of Scientific and Technical Information (OSTI.GOV)
Steed, Chad Allen
EDENx is a multivariate data visualization tool that allows interactive user driven analysis of large-scale data sets with high dimensionality. EDENx builds on our earlier system, called EDEN to enable analysis of more dimensions and larger scale data sets. EDENx provides an initial overview of summary statistics for each variable in the data set under investigation. EDENx allows the user to interact with graphical summary plots of the data to investigate subsets and their statistical associations. These plots include histograms, binned scatterplots, binned parallel coordinate plots, timeline plots, and graphical correlation indicators. From the EDENx interface, a user can selectmore » a subsample of interest and launch a more detailed data visualization via the EDEN system. EDENx is best suited for high-level, aggregate analysis tasks while EDEN is more appropriate for detail data investigations.« less
Al-Saleh, Ayman; Alazzoni, Ashraf; Al Shalash, Saleh; Ye, Chenglin; Mbuagbaw, Lawrence; Thabane, Lehana; Jolly, Sanjit S.
2014-01-01
Background High-sensitivity cardiac troponin assays have been adopted by many clinical centres worldwide; however, clinicians are uncertain how to interpret the results. We sought to assess the utility of these assays in diagnosing acute myocardial infarction (MI). Methods We carried out a systematic review and meta-analysis of studies comparing high-sensitivity with conventional assays of cardiac troponin levels among adults with suspected acute MI in the emergency department. We searched MEDLINE, EMBASE and Cochrane databases up to April 2013 and used bivariable random-effects modelling to obtain summary parameters for diagnostic accuracy. Results We identified 9 studies that assessed the use of high-sensitivity troponin T assays (n = 9186 patients). The summary sensitivity of these tests in diagnosing acute MI at presentation to the emergency department was estimated to be 0.94 (95% confidence interval [CI] 0.89–0.97); for conventional tests, it was 0.72 (95% CI 0.63–0.79). The summary specificity was 0.73 (95% CI 0.64–0.81) for the high-sensitivity assay compared with 0.95 (95% CI 0.93–0.97) for the conventional assay. The differences in estimates of the summary sensitivity and specificity between the high-sensitivity and conventional assays were statistically significant (p < 0.01). The area under the curve was similar for both tests carried out 3–6 hours after presentation. Three studies assessed the use of high-sensitivity troponin I assays and showed similar results. Interpretation Used at presentation to the emergency department, the high-sensitivity cardiac troponin assay has improved sensitivity, but reduced specificity, compared with the conventional troponin assay. With repeated measurements over 6 hours, the area under the curve is similar for both tests, indicating that the major advantage of the high-sensitivity test is early diagnosis. PMID:25295240
Scalable Emergency Response System for Oceangoing Assets. Final Summary Report
2009-01-20
Developed for platform defense of submarines and surface ships at sea and in port, the iRobot High Speed UUV enables rapid transit with respect to a ... high level decontamination, resulting in a return to port Decision Making Option C is to sealift via decontamination vessel contingent, and perform a ...the world aboard a prepared LCAC.48 A high - speed , over- 47 One Marine’s View. Retrieved from http://www.onemarinesview.com/one_marines_view/2006/09
ERIC Educational Resources Information Center
Spain, William H.; And Others
This project consists of two parallel yet interrelated studies, one focusing on the full cohort of approximately 9,000 Level III (Grade 12) high school students in Newfoundland and Labrador at the end of the 1988-89 school year, and a second, which focuses on the full year cohort of 2109 students (grades seven to Level III) who dropped out of…
2008-05-01
communicate with other weapon models In a mission-level simulation; (3) introduces the four configuration levels of the M&S framework; and (4) presents a cost ...and Disadvantages ....................................................................... 26 6 COST -EFFECTIVE M&S LABORATORY PLAN...25 23 Weapon Model Sample Time and Average TET Displayed on the Target PC ..... 26 24 Design and Cost of an
VanGeest, Jonathan B; Wynia, Matthew K; Cummins, Deborah S; Wilson, Ira B
2002-06-01
This study examined the test-retest reliability of physicians' self-reported manipulation of reimbursement rules for patients. The test-retest reliability of self-report of three specific tactics were examined: (1) exaggerating the severity of patients' conditions, (2) changing a patient's official (billing) diagnosis, and (3) reporting signs or symptoms that patients did not have. The reliability of a scaled summary measure of physicians' manipulation of reimbursement rules was also assessed. Overall, the authors found high levels of test-retest agreement across all three items and the summary measure. These findings suggest that self-report can be used to produce reliable data on this controversial issue. Specifically, the three items reported here can be used to produce a reliable summary measure of physicians' manipulation of reimbursement rules to help patients obtain care that physicians perceive as necessary.
ERIC Educational Resources Information Center
Doherty, Cait
2009-01-01
This article summarizes an original conference, organised by the Child Care Research Forum (http://www.qub.ac.uk/sites/ccrf/), which brought together experts from all over Northern Ireland to showcase some of the wealth of research with children and young people that is going on in the country today. Developed around the six high-level outcomes of…
Benchmarking and beyond. Information trends in home care.
Twiss, Amanda; Rooney, Heather; Lang, Christine
2002-11-01
With today's benchmarking concepts and tools, agencies have the unprecedented opportunity to use information as a strategic advantage. Because agencies are demanding more and better information, benchmark functionality has grown increasingly sophisticated. Agencies now require a new type of analysis, focused on high-level executive summaries while reducing the current "data overload."
Performance of Hearing Protectors in Impulse Noise
2000-09-01
report: ADPO10340 thru ADP010346 UNCLASSIFIED 3-1 Performance of Hearing Protectors in Impulse Noise K. Buck French German Research Institute BP 34...5 rue du G6n~ral Cassagnou 68301 Saint-Louis CEDEX France Summary adapted to the high levels to which the devices will The present paper describes the
Racial and Gender Gaps in Academic Achievement. Report Summary.
ERIC Educational Resources Information Center
Dulaney, Chuck; Banks, Karen
This report summarizes the level of academic achievement, and the extent of racial and gender gaps in that achievement, of students in North Carolina's Wake County Public School System (WCPSS). The comparison was conducted using 1993 End-of-Grade (EOG) tests; low income group EOG test performance; 1993 writing tests and high school writing…
Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-29
... DEPARTMENT OF ENERGY Notice of Availability of Draft Waste Incidental to Reprocessing Evaluation...: Notice of availability. SUMMARY: The Department of Energy (DOE) announces the availability of a draft... Center in West Valley, New York, are waste incidental to reprocessing and thus are not high-level...
THE COMPREHENSIVE EDUCATIONAL PROGRAM FOR WEST VIRGINIA SCHOOLS.
ERIC Educational Resources Information Center
SMITH, REX M.
THE COMPREHENSIVE EDUCATIONAL PROGRAM IS DEFINED AS ONE WHICH MEETS THE NEEDS OF ALL STUDENTS AT ALL LEVELS BY PROVIDING COMPREHENSIVE AND ELECTIVE PROGRAMS FOR THOSE STUDENTS REQUIRING SALABLE SKILLS UPON GRADUATION FROM HIGH SCHOOL, AS WELL AS A BROAD ELECTIVE PROGRAM FOR THOSE WHO WISH TO CONTINUE THEIR EDUCATION. INCLUDED ARE SUMMARIES OF THE…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fox, K.; Fowley, M.
A full-scale, transparent mock-up of the Hanford Tank Waste Treatment and Immobilization Project High Level Waste glass melter riser and pour spout has been constructed to allow for testing with visual feedback of particle settling, accumulation, and resuspension when operating with a controlled fraction of crystals in the glass melt. Room temperature operation with silicone oil and magnetite particles simulating molten glass and spinel crystals, respectively, allows for direct observation of flow patterns and settling patterns. The fluid and particle mixture is recycled within the system for each test.
Levels of Evidence: Cancer Genetics Studies (PDQ®)—Health Professional Version
Levels of Evidence for Cancer Genetics Studies addresses the process and challenges of developing evidence-based summaries. Get information about how to weigh the strength of the evidence from cancer genetics studies in this summary for clinicians.
EPA State-level Summaries of FracFocus 1 Hydraulic Fracturing Data
The EPA developed state-level summaries of chemical and water use using the project database developed from FracFocus 1.0 disclosures with some limited background information on oil and gas production, geology, and regulations for the state.
Gene- and pathway-based association tests for multiple traits with GWAS summary statistics.
Kwak, Il-Youp; Pan, Wei
2017-01-01
To identify novel genetic variants associated with complex traits and to shed new insights on underlying biology, in addition to the most popular single SNP-single trait association analysis, it would be useful to explore multiple correlated (intermediate) traits at the gene- or pathway-level by mining existing single GWAS or meta-analyzed GWAS data. For this purpose, we present an adaptive gene-based test and a pathway-based test for association analysis of multiple traits with GWAS summary statistics. The proposed tests are adaptive at both the SNP- and trait-levels; that is, they account for possibly varying association patterns (e.g. signal sparsity levels) across SNPs and traits, thus maintaining high power across a wide range of situations. Furthermore, the proposed methods are general: they can be applied to mixed types of traits, and to Z-statistics or P-values as summary statistics obtained from either a single GWAS or a meta-analysis of multiple GWAS. Our numerical studies with simulated and real data demonstrated the promising performance of the proposed methods. The methods are implemented in R package aSPU, freely and publicly available at: https://cran.r-project.org/web/packages/aSPU/ CONTACT: weip@biostat.umn.eduSupplementary information: Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
Cichonska, Anna; Rousu, Juho; Marttinen, Pekka; Kangas, Antti J; Soininen, Pasi; Lehtimäki, Terho; Raitakari, Olli T; Järvelin, Marjo-Riitta; Salomaa, Veikko; Ala-Korpela, Mika; Ripatti, Samuli; Pirinen, Matti
2016-07-01
A dominant approach to genetic association studies is to perform univariate tests between genotype-phenotype pairs. However, analyzing related traits together increases statistical power, and certain complex associations become detectable only when several variants are tested jointly. Currently, modest sample sizes of individual cohorts, and restricted availability of individual-level genotype-phenotype data across the cohorts limit conducting multivariate tests. We introduce metaCCA, a computational framework for summary statistics-based analysis of a single or multiple studies that allows multivariate representation of both genotype and phenotype. It extends the statistical technique of canonical correlation analysis to the setting where original individual-level records are not available, and employs a covariance shrinkage algorithm to achieve robustness.Multivariate meta-analysis of two Finnish studies of nuclear magnetic resonance metabolomics by metaCCA, using standard univariate output from the program SNPTEST, shows an excellent agreement with the pooled individual-level analysis of original data. Motivated by strong multivariate signals in the lipid genes tested, we envision that multivariate association testing using metaCCA has a great potential to provide novel insights from already published summary statistics from high-throughput phenotyping technologies. Code is available at https://github.com/aalto-ics-kepaco anna.cichonska@helsinki.fi or matti.pirinen@helsinki.fi Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.
Cichonska, Anna; Rousu, Juho; Marttinen, Pekka; Kangas, Antti J.; Soininen, Pasi; Lehtimäki, Terho; Raitakari, Olli T.; Järvelin, Marjo-Riitta; Salomaa, Veikko; Ala-Korpela, Mika; Ripatti, Samuli; Pirinen, Matti
2016-01-01
Motivation: A dominant approach to genetic association studies is to perform univariate tests between genotype-phenotype pairs. However, analyzing related traits together increases statistical power, and certain complex associations become detectable only when several variants are tested jointly. Currently, modest sample sizes of individual cohorts, and restricted availability of individual-level genotype-phenotype data across the cohorts limit conducting multivariate tests. Results: We introduce metaCCA, a computational framework for summary statistics-based analysis of a single or multiple studies that allows multivariate representation of both genotype and phenotype. It extends the statistical technique of canonical correlation analysis to the setting where original individual-level records are not available, and employs a covariance shrinkage algorithm to achieve robustness. Multivariate meta-analysis of two Finnish studies of nuclear magnetic resonance metabolomics by metaCCA, using standard univariate output from the program SNPTEST, shows an excellent agreement with the pooled individual-level analysis of original data. Motivated by strong multivariate signals in the lipid genes tested, we envision that multivariate association testing using metaCCA has a great potential to provide novel insights from already published summary statistics from high-throughput phenotyping technologies. Availability and implementation: Code is available at https://github.com/aalto-ics-kepaco Contacts: anna.cichonska@helsinki.fi or matti.pirinen@helsinki.fi Supplementary information: Supplementary data are available at Bioinformatics online. PMID:27153689
Adaptation and fallibility in experts' judgments of novice performers.
Larson, Jeffrey S; Billeter, Darron M
2017-02-01
Competition judges are often selected for their expertise, under the belief that a high level of performance expertise should enable accurate judgments of the competitors. Contrary to this assumption, we find evidence that expertise can reduce judgment accuracy. Adaptation level theory proposes that discriminatory capacity decreases with greater distance from one's adaptation level. Because experts' learning has produced an adaptation level close to ideal performance standards, they may be less able to discriminate among lower-level competitors. As a result, expertise increases judgment accuracy of high-level competitions but decreases judgment accuracy of low-level competitions. Additionally, we demonstrate that, consistent with an adaptation level theory account of expert judgment, experts systematically give more critical ratings than intermediates or novices. In summary, this work demonstrates a systematic change in human perception that occurs as task learning increases. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
2015-06-03
example, all atomic clocks for the European satellite -based global positioning system GALLILEO were manufactured in Neuchatel. With the integration...realization of numerous other exciting devices in various areas like advancement of sensors and nano- technological devices. Summary of Project...losses of the resonator . Achieving passive femtosecond pulse formation at these record-high power levels will require eliminating any destabilizing
High Temperature Gas-Cooled Test Reactor Point Design: Summary Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sterbentz, James William; Bayless, Paul David; Nelson, Lee Orville
2016-01-01
A point design has been developed for a 200-MW high-temperature gas-cooled test reactor. The point design concept uses standard prismatic blocks and 15.5% enriched uranium oxycarbide fuel. Reactor physics and thermal-hydraulics simulations have been performed to characterize the capabilities of the design. In addition to the technical data, overviews are provided on the technology readiness level, licensing approach, and costs of the test reactor point design.
High Temperature Gas-Cooled Test Reactor Point Design: Summary Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sterbentz, James William; Bayless, Paul David; Nelson, Lee Orville
2016-03-01
A point design has been developed for a 200-MW high-temperature gas-cooled test reactor. The point design concept uses standard prismatic blocks and 15.5% enriched uranium oxycarbide fuel. Reactor physics and thermal-hydraulics simulations have been performed to characterize the capabilities of the design. In addition to the technical data, overviews are provided on the technology readiness level, licensing approach, and costs of the test reactor point design.
ERIC Educational Resources Information Center
Nettles, Mary Frances
2014-01-01
The NFSMI Research Summary is a continuing series of summaries reporting recently completed research and research-based resources funded by the National Food Service Management Institute. The following research studies are summarized in this article: (1) Succession Planning for Management Level Staff in School Nutrition Programs; (2)…
Alla, Arben; Czabanowska, Katarzyna; Kijowska, Violetta; Roshi, Enver; Burazeri, Genc
2012-01-01
Our aim was to validate an international instrument measuring self-perceived competency level of family physicians in Albania. A representative sample of 57 family physicians operating in primary health care services was interviewed twice in March-April 2012 in Tirana (26 men and 31 women; median age: 46 years, inter-quartile range: 38-56 years). A structured questionnaire was administered [and subsequently re-administered after two weeks (test-retest)] to all family physicians aiming to self-assess physicians' level of abilities, skills and competencies regarding different domains of quality of health care. The questionnaire included 37 items organized into 6 subscales/domains. Answers for each item of the tool ranged from 1 ("novice" physicians) to 5 ("expert" physicians). An overall summary score (range: 37-185) and a subscale summary score for each domain were calculated for the test and retest procedures. Cronbach's alpha was used to assess the internal consistency for both the test and the retest procedures, whereas Spearman's rho was employed to assess the stability over time (test-retest reliability) of the instrument. Cronbach's alpha was 0.87 for the test and 0.86 for the retest procedure. Overall, Spearman's rho was 0.84 (P<0.001). The overall summary score for the 37 items of the instrument was 96.3±10.0 for the test and 97.3±10.1 for the retest. All the subscale summary scores were very similar for the test and the retest procedure. This study provides evidence on cross-cultural adaptation of an international instrument taping self-perceived level of competencies of family physicians in Albania. The questionnaire displayed a satisfactory internal consistency for both test and retest procedures in this sample of family physicians in Albania. Furthermore, the high test-retest reliability (stability over time) of the instrument suggests a good potential for wide scale application to nationally representative samples of family physicians in Albanian populations.
ERIC Educational Resources Information Center
Koon, Sharon; Petscher, Yaacov; Foorman, Barbara R.
2014-01-01
State education leaders are often interested in identifying schools that have demonstrated success with improving the literacy of students who are at the highest level of risk for reading difficulties. The identification of these schools that are "beating the odds" is typically accomplished by comparing a school's observed performance on…
Chemical & Biological Point Detection Decontamination
2002-04-01
high priority in biological defense. Research on multivalent assays is also ongoing. Biased libraries, generated from immunized animals, or unbiased ...2003 TBD decontamination and modeling and simulation I I The Chem-Bio Point Detection Roadmap The summary level updated and expanded Bio Point... Molecular Imprinted Polymer Sensor, Dendrimer-based Antibody Assays, Pyrolysis-GC-ion mobility spectrometry, and surface enhanced Raman spectroscopy. Data
Levels of Evidence: Supportive and Palliative Care Studies (PDQ®)—Health Professional Version
Levels of Evidence for Supportive and Palliative Care Summaries includes cited references primarily from the peer-reviewed biomedical literature. Get detailed information about how to weigh the strength of the evidence obtained in supportive and palliative care studies in this clinician summary.
Differentiating Dark Triad Traits Within and Across Interpersonal Circumplex Surfaces.
Dowgwillo, Emily A; Pincus, Aaron L
2017-01-01
Recent discussions surrounding the Dark Triad (narcissism, psychopathy, and Machiavellianism) have centered on areas of distinctiveness and overlap. Given that interpersonal dysfunction is a core feature of Dark Triad traits, the current study uses self-report data from 562 undergraduate students to examine the interpersonal characteristics associated with narcissism, psychopathy, and Machiavellianism on four interpersonal circumplex (IPC) surfaces. The distinctiveness of these characteristics was examined using a novel bootstrapping methodology for computing confidence intervals around circumplex structural summary method parameters. Results suggest that Dark Triad traits exhibit distinct structural summary method parameters with narcissism characterized by high dominance, psychopathy characterized by a blend of high dominance and low affiliation, and Machiavellianism characterized by low affiliation on the problems, values, and efficacies IPC surfaces. Additionally, there was some heterogeneity in findings for different measures of psychopathy. Gender differences in structural summary parameters were examined, finding similar parameter values despite mean-level differences in Dark Triad traits. Finally, interpersonal information was integrated across different IPC surfaces to create profiles associated with each Dark Triad trait and to provide a more in-depth portrait of associated interpersonal dynamics. © The Author(s) 2016.
Hierarchical video summarization
NASA Astrophysics Data System (ADS)
Ratakonda, Krishna; Sezan, M. Ibrahim; Crinon, Regis J.
1998-12-01
We address the problem of key-frame summarization of vide in the absence of any a priori information about its content. This is a common problem that is encountered in home videos. We propose a hierarchical key-frame summarization algorithm where a coarse-to-fine key-frame summary is generated. A hierarchical key-frame summary facilitates multi-level browsing where the user can quickly discover the content of the video by accessing its coarsest but most compact summary and then view a desired segment of the video with increasingly more detail. At the finest level, the summary is generated on the basis of color features of video frames, using an extension of a recently proposed key-frame extraction algorithm. The finest level key-frames are recursively clustered using a novel pairwise K-means clustering approach with temporal consecutiveness constraint. We also address summarization of MPEG-2 compressed video without fully decoding the bitstream. We also propose efficient mechanisms that facilitate decoding the video when the hierarchical summary is utilized in browsing and playback of video segments starting at selected key-frames.
Meteorological annual report for 1995 at the Savannah River Site
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hunter, C.H.; Tatum, C.P.
1996-12-01
The Environmental Technology Section (ETS) of the Savannah River Technology Center (SRTC) collects, archives, and analyzes basic meteorological data supporting a variety of activities at SRS. These activities include the design, construction, and operation of nuclear and non-nuclear facilities, emergency response, environmental compliance, resource management, and environmental research. This report contains tabular and graphical summaries of data collected during 1995 for temperature, precipitation, relative humidity, wind, barometric pressure, and solar radiation. Most of these data were collected at the central Climatology Facility. Summaries of temperature and relative humidity were generated with data from the lowest level of measurement at themore » Central Climatology Site tower (13 feet above ground). (Relative humidity is calculated from measurements of dew-point temperature.) Wind speed summaries were generated with data from the second measurement level (58 feet above ground). Wind speed measurements from this level are believed to best represent open, well-exposed areas of the Site. Precipitation summaries were based on data from the Building 773-A site since quality control algorithms for the central Climatology Facility rain gauge data were not finalized at the time this report was prepared. This report also contains seasonal and annual summaries of joint occurrence frequencies for selected wind speed categories by 22.5 degree wind direction sector (i.e., wind roses). Wind rose summaries are provided for the 200-foot level of the Central Climatology tower and for each of the eight 200-foot area towers.« less
5 CFR 430.206 - Planning performance.
Code of Federal Regulations, 2013 CFR
2013-01-01
... summary level, including at least one critical element and any non-critical element(s). (5) Each... summary levels (pattern A as specified in § 430.208(d)(1)) shall not include non-critical elements. (7) An... non-critical elements. (8) Elements and standards shall be established as follows— (i) For a critical...
Hawaiian volcano observatory summary 103; Part I, seismic data, January to December 2003
Nakata, Jennifer S.; Heliker, C.; Orr, T.; Hoblitt, R.
2004-01-01
The Hawaiian Volcano Observatory (HVO) summary presents seismic data gathered during the year and a chronological narrative describing the volcanic events. The seismic summary is offered without interpretation as a source of preliminary data. It is complete in the sense that most data for events of M= 1.5 routinely gathered by the Observatory are included. The emphasis in collection of tilt and deformation data has shifted from quarterly measurements at a few water-tube tilt stations ('wet' tilt) to a larger number of continuously recording borehole tiltmeters, repeated measurements at numerous spirit-level tilt stations ('dry' tilt), and surveying of level and trilateration networks. Because of the large quantity of deformation data now gathered and differing schedules of data reduction, the seismic and deformation summaries are published separately. The HVO summaries have been published in various forms since 1956. Summaries prior to 1974 were issued quarterly, but cost, convenience of preparation and distribution, and the large quantities of data dictated an annual publication beginning with Summary 74 for the year 1974. Summary 86 (the introduction of CUSP at HVO) includes a description of the seismic instrumentation, calibration, and processing used in recent years. The present summary includes background information on the seismic network and processing to allow use of the data and to provide an understanding of how they were gathered.
Hawaiian Volcano Observatory summary 100; Part 1, seismic data, January to December 2000
Nakata, Jennifer S.
2001-01-01
The Hawaiian Volcano Observatory (HVO) summary presents seismic data gathered during the year and a chronological narrative describing the volcanic events. The seismic summary is offered without interpretation as a source of preliminary data. It is complete in the sense that all data for events of M≥1.5 routinely gathered by the Observatory are included. The emphasis in collection of tilt and deformation data has shifted from quarterly measurements at a few water-tube tilt stations (“wet” tilt) to a larger number of continuously recording borehole tiltmeters, repeated measurements at numerous spirit-level tilt stations (“dry” tilt), and surveying of level and trilateration networks. Because of the large quantity of deformation data now gathered and differing schedules of data reduction, the seismic and deformation summaries are published separately. The HVO summaries have been published in various forms since 1956. Summaries prior to 1974 were issued quarterly, but cost, convenience of preparation and distribution, and the large quantities of data dictated an annual publication beginning with Summary 74 for the year 1974. Summary 86 (the introduction of CUSP at HVO) includes a description of the seismic instrumentation, calibration, and processing used in recent years. The present summary includes enough background information on the seismic network and processing to allow use of the data and to provide an understanding of how they were gathered.
Hawaiian Volcano Observatory summary 101: Part 1, seismic data, January to December 2001
Nakata, Jennifer S.; Chronological summary by Heliker, C.
2002-01-01
The Hawaiian Volcano Observatory (HVO) summary presents seismic data gathered during the year and a chronological narrative describing the volcanic events. The seismic summary is offered without interpretation as a source of preliminary data. It is complete in the sense that all data for events of M>1.5 routinely gathered by the Observatory are included. The emphasis in collection of tilt and deformation data has shifted from quarterly measurements at a few water-tube tilt stations ("wet" tilt) to a larger number of continuously recording borehole tiltmeters, repeated measurements at numerous spirit-level tilt stations ("dry" tilt), and surveying of level and trilateration networks. Because of the large quantity of deformation data now gathered and differing schedules of data reduction, the seismic and deformation summaries are published separately. The HVO summaries have been published in various forms since 1956. Summaries prior to 1974 were issued quarterly, but cost, convenience of preparation and distribution, and the large quantities of data dictated an annual publication beginning with Summary 74 for the year 1974. Summary 86 (the introduction of CUSP at HVO) includes a description of the seismic instrumentation, calibration, and processing used in recent years. The present summary includes enough background information on the seismic network and processing to allow use of the data and to provide an understanding of how they were gathered.
Targeted Lipidomic Analysis of Oxysterols in the Embryonic Central Nervous System
Wang, Yuqin; Sousa, Kyle M.; Bodin, Karl; Theofilopoulos, Spyridon; Sacchetti, Paola; Hornshaw, Martin; Woffendin, Gary; Karu, Kersti; Sjövall, Jan; Arenas, Ernest; Griffiths, William J.
2009-01-01
Summary In this study two regions of embryonic (E11) mouse central nervous system (CNS) have been profiled for their unesterified sterol content. Using high-performance liquid chromatography (HPLC) – mass spectrometry (MS) and tandem mass spectrometry (MSn) low levels of oxysterols (estimated 2 – 165 ng/g wet weight) were identified in cortex (Ctx) and spinal cord (Sc). The identified oxysterols include 7α-, 7β-, 22R-, 24S-, 25- and 27-hydroxycholesterol; 24,25- and 24,27-dihydroxycholesterol; and 24S,25-epoxycholesterol. Of these, 24S-hydroxycholesterol is biosynthesised exclusively in brain. In comparison to adult mouse where the 24S-hydroxycholesterol level is about 40 μg/g in brain the level of 24S-hydroxycholesterol reported here (estimated 26 ng/g in Ctx and 13 ng/g in Sc) is extremely low. Interestingly, the level of 24S,25-epoxycholesterol in both CNS regions (estimated 165 ng/g in Ctx and 91 ng/g in Sc) is somewhat higher than the levels of the hydroxycholesterols. This oxysterol is formed in parallel to cholesterol via a shunt of the mevalonate pathway and its comparatively high abundance may be a reflection of a high rate of cholesterol synthesis at this stage of development. Levels of cholesterol (estimated 1.25 mg/g in Ctx and 1.15 mg/g in Sc) and its precursors were determined by gas chromatography – mass spectrometry (GC-MS). In both CNS regions cholesterol levels were found to be lower than those reported in the adult, but in relation to cholesterol the levels of cholesterol precursors were higher than found in adult indicating a high rate of cholesterol synthesis. In summary, our data provide evidence for the presence of endogenous oxysterols in two brain regions of the developing CNS. Moreover, while most of the enzymes involved in hydroxysterol synthesis are minimally active at E11, our results suggest that the mevalonate pathway is significantly active, opening up the possibility for a function of 24S,25-epoxycholesterol during brain development. PMID:19381367
ERIC Educational Resources Information Center
Corbeil, Giselle
2001-01-01
Analyzes differences between experts and university students of various academic levels in the application of the macrorules of deletion, generalization, and construction of text summaries. Learners of French as a second language wrote summaries of a French text in French as well as in English, their mother tongue, while professors of French and…
United Information Services, Inc. , CRAY 1-s/2000, FORTRAN CFT 1. 10. Validation summary report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1983-12-13
This Validation Summary Report (VSR) for the United Information Services, Inc., FORTRAN CFT 1.10 running under the COS Level C12 1.11 provides a consolidated summary of the results obtained from the validation of the subject compiler against the 1978 FORTRAN Standard (X3.9-1978/FIPS PUB 69). The compiler was validated against the Full Level FORTRAN level of FIPS PUB 69. The VSR is made up of several sections showing all the discrepancies found -if any. These include an overview of the validation which lists all categories of discrepancies within X3.9-1978, and a detailed listing of discrepancies together with the tests which failed.
Private v. Public Rights (Grade Level: High School, 9-12)
ERIC Educational Resources Information Center
Fieth, Stacie; Deason, Neil
2005-01-01
Designed for grades 9-12, this lesson plan aims to let students learn how the Fifth Amendment to the Constitution relates to private property and how the power of eminent domain was defined in a recent Supreme Court case. Students will review summaries from Kelo v. New London to gain a better understanding of the case, which dealt with the limits…
Vertical Compliance Trends in KBOS OPD Arrival Redesign
NASA Technical Reports Server (NTRS)
Stewart, Michael Jeffrey; Matthews, Bryan L.; Feary, Michael S.
2016-01-01
This report is a high-level summary of vertical compliance trends and overall rates of Area Navigation Optimized Profile Descent (RNAV OPD) utilization for Boston Logan International Airport. Specifically, we investigated trends from three RNAV OPDs and the subsequent redesigned iterations of those procedures: OOSHN3 to OOSHN4, ROBUC1 to ROBUC2, and QUABN3 to JFUND1.
ERIC Educational Resources Information Center
Weiss, Michael; Brock, Thomas; Sommo, Colleen; Rudd, Timothy; Turner, Mary Clair
2011-01-01
Community colleges across the United States face a difficult challenge. On the one hand, they are "open access" institutions, with a mission to serve students from all backgrounds and at varying levels of college readiness. On the other hand, they must uphold high academic standards in order to maintain accreditation and prepare students…
ERIC Educational Resources Information Center
Galletly, Susan A.; Knight, Bruce Allen
2011-01-01
The PISA studies of reading achievement of 15 year old students in OECD and partner nations show Anglophone nations to have continuing high proportions of weak readers (less than or equal to Level 2), with no improvement in this area from 2000 to 2006 (OECD, "Science competencies for tomorrow's world: Executive summary," 2007). The…
ERIC Educational Resources Information Center
Reumann-Moore, Rebecca; Lawrence, Nancy; Sanders, Felicia; Christman, Jolley Bruce; Duffy, Mark
2011-01-01
The Bill and Melinda Gates Foundation has invested in the development and dissemination of high-quality instructional and formative assessment tools to support teachers' incorporation of the Core Common State Standards (CCSS) into their classroom instruction. Literacy experts have developed a framework and a set of templates that teachers can use…
ERIC Educational Resources Information Center
Garet, Michael S.; Heppen, Jessica B.; Walters, Kirk; Parkinson, Julia; Smith, Toni M.; Song, Mengli; Garrett, Rachel; Yang, Rui; Borman, Geoffrey D.
2016-01-01
Improving math achievement among U.S. students remains a high priority as results from recent math assessments continue to show room for improvement. For example, 60 percent of fourth-graders scored below the proficient level on the 2015 National Assessment of Educational Progress. On the most recent Program for International Student Assessment's…
Scheduling language and algorithm development study. Volume 1: Study summary and overview
NASA Technical Reports Server (NTRS)
1974-01-01
A high level computer programming language and a program library were developed to be used in writing programs for scheduling complex systems such as the space transportation system. The objectives and requirements of the study are summarized and unique features of the specified language and program library are described and related to the why of the objectives and requirements.
Long-Lived In-Situ Solar System Explorer (LLISSE)
NASA Technical Reports Server (NTRS)
Kremic, Tibor; Hunter, Gary; Rock, Jennifer
2017-01-01
This presentation provides an update on development of the Long-Lived In-situ Solar System Explorer (LLISSE). LLISSE is a small probe being developed to provide long-term measurements of simple but important scientific parameters from the surface of Venus. High level summary of recent activities and progress is provided. LLISSE is a small and completely independent probe for Venus surface applications
High Energy Astronomy Observatory, Mission C, Phase A. Volume 1: Executive summary
NASA Technical Reports Server (NTRS)
1972-01-01
A summary of the Phase A of the High Energy Astronomy Observatory Mission-C (HEAO-C) is presented. The mission, baseline experiments, observatory design, and spacecraft subsystems are described, and the principal mission considerations are discussed. A summary is included of the general recommendations.
Zheng, Jie; Erzurumluoglu, A Mesut; Elsworth, Benjamin L; Kemp, John P; Howe, Laurence; Haycock, Philip C; Hemani, Gibran; Tansey, Katherine; Laurin, Charles; Pourcain, Beate St; Warrington, Nicole M; Finucane, Hilary K; Price, Alkes L; Bulik-Sullivan, Brendan K; Anttila, Verneri; Paternoster, Lavinia; Gaunt, Tom R; Evans, David M; Neale, Benjamin M
2017-01-15
LD score regression is a reliable and efficient method of using genome-wide association study (GWAS) summary-level results data to estimate the SNP heritability of complex traits and diseases, partition this heritability into functional categories, and estimate the genetic correlation between different phenotypes. Because the method relies on summary level results data, LD score regression is computationally tractable even for very large sample sizes. However, publicly available GWAS summary-level data are typically stored in different databases and have different formats, making it difficult to apply LD score regression to estimate genetic correlations across many different traits simultaneously. In this manuscript, we describe LD Hub - a centralized database of summary-level GWAS results for 173 diseases/traits from different publicly available resources/consortia and a web interface that automates the LD score regression analysis pipeline. To demonstrate functionality and validate our software, we replicated previously reported LD score regression analyses of 49 traits/diseases using LD Hub; and estimated SNP heritability and the genetic correlation across the different phenotypes. We also present new results obtained by uploading a recent atopic dermatitis GWAS meta-analysis to examine the genetic correlation between the condition and other potentially related traits. In response to the growing availability of publicly accessible GWAS summary-level results data, our database and the accompanying web interface will ensure maximal uptake of the LD score regression methodology, provide a useful database for the public dissemination of GWAS results, and provide a method for easily screening hundreds of traits for overlapping genetic aetiologies. The web interface and instructions for using LD Hub are available at http://ldsc.broadinstitute.org/ CONTACT: jie.zheng@bristol.ac.ukSupplementary information: Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.
Zahabi, Maryam; Zhang, Wenjuan; Pankok, Carl; Lau, Mei Ying; Shirley, James; Kaber, David
2017-11-01
Many occupations require both physical exertion and cognitive task performance. Knowledge of any interaction between physical demands and modalities of cognitive task information presentation can provide a basis for optimising performance. This study examined the effect of physical exertion and modality of information presentation on pattern recognition and navigation-related information processing. Results indicated males of equivalent high fitness, between the ages of 18 and 34, rely more on visual cues vs auditory or haptic for pattern recognition when exertion level is high. We found that navigation response time was shorter under low and medium exertion levels as compared to high intensity. Navigation accuracy was lower under high level exertion compared to medium and low levels. In general, findings indicated that use of the haptic modality for cognitive task cueing decreased accuracy in pattern recognition responses. Practitioner Summary: An examination was conducted on the effect of physical exertion and information presentation modality in pattern recognition and navigation. In occupations requiring information presentation to workers, who are simultaneously performing a physical task, the visual modality appears most effective under high level exertion while haptic cueing degrades performance.
Locke, Glenn L.
2008-01-01
The U.S. Geological Survey, in cooperation with the U.S. Department of Energy, Office of Civilian Radioactive Waste Management, collected, compiled, and summarized hydrologic data in the Yucca Mountain region of southern Nevada and eastern California. These data were collected to allow assessments of ground-water resources during activities to determine the potential suitability or development of Yucca Mountain for storing high-level nuclear waste. Data collected from January through December 2005 are provided for ground-water levels at 35 boreholes and 1 fissure (Devils Hole), ground-water discharge at 5 springs, ground-water levels and discharge at 1 flowing borehole, and total reported ground-water withdrawals within Crater Flat, Jackass Flats, Mercury Valley, and the Amargosa Desert. Ground-water level, discharge, and withdrawal data collected by other agencies, or as part of other programs, are provided. A statistical summary of ground-water levels at seven boreholes in Jackass Flats is presented for 1992-2005 to indicate potential effects of ground-water withdrawals associated with U.S. Department of Energy activities near Yucca Mountain. The statistical summary includes the annual number of measurements; maximum, minimum, and median water-level altitudes; and average deviation of measured water-level altitudes compared to the 1992-93 baseline period. At seven boreholes in Jackass Flats, median water levels for 2005 were slightly higher (0.4-2.7 feet) than the median water levels for 1992-93.
Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-19
... inspection by FDA during the review of marketing applications. This draft guidance describes a recommended... associated with marketing applications. The summary level clinical site dataset: Contains data from all... represent the Agency's current thinking on this topic. It does not create or confer any rights for or on any...
Influence of low and high pressure baroreceptors on plasma renin activity in humans
NASA Technical Reports Server (NTRS)
Mark, A. L.; Abboud, F. M.; Fitz, A. E.
1977-01-01
The effects of low and high pressure baroreceptors on plasma renin activity (immunoassay) were evaluated using graded lower body suction (LBS) in six healthy men. LBS at -10 and -20 mmHg for 10 min decreased central venous pressure without changing arterial pressure and thereby presumably reduced low but not high pressure baroreceptor inhibition of renin release. LBS at these levels produced forearm vasoconstriction, but did not increase renin. LBS at -40 mmHG decreased central venous and arterial pulse pressure and thus reduced both low and high pressure baroreceptor inhibition. LBS at this level produced forearm vasoconstriction and tachycardia and increased renin. In summary, reduction in low pressure baroreceptor inhibition in humans did not increase renin in the presence of physiological tonic inhibition from high pressure baroreceptors. Increases in renin did not occur until there was combined reduction of high and low pressure baroreceptor inhibition on plasma renin activity.
National Environmental/Energy Workforce Assessment, National Summary: Alabama-Indiana. Volume One.
ERIC Educational Resources Information Center
National Field Research Center Inc., Iowa City, IA.
This report is one in a four-volume National Summary which presents existing workforce levels, training programs and career potentials for each of the states, Washington, D.C., Puerto Rico, and the Virgin Islands. Each individual state program summary is followed by a depiction of the current and projected (1976-1981) workforce figures for the…
ERIC Educational Resources Information Center
National Field Research Center Inc., Iowa City, IA.
This report is one in a four-volume National Summary which presents existing workforce levels, training programs and career potentials for each of the states, Washington, D.C., Puerto Rico, and the Virgin Islands. Each individual state program summary is followed by a depiction of the current and projected (1976-1981) workforce figures for the…
Hidaka, Kumi; Matsuoka, Mio; Kajiwara, Kanako; Hinokiyama, Hiromi; Mito, Saori; Doi, Seiko; Konishi, Eriko; Ibata, Takeshi; Komuro, Ryutaro; lijima, Shohei
2013-12-01
Our nutrition support team (NST) designed the NST summary for cooperation among personnel providing medical care for nutritional management of high-need patients in our area. After the introduction of the NST fee under the health care system, the number of summary publications decreased. The requested NST fee is necessary for publication of a nutritional care plan and report upon patient discharge. We hypothesized that the nutritional care plan and discharge report were being substituted for the NST summary at the time of patient discharge. We retrospectively investigated 192 cases with NST fee. There were only 13 cases of overlapping publication, and the NST summary was necessary for 107 of 179 cases in which no NST summary had been prepared. Since the space on the report form is limited, it can provide only limited information. However, the NST summary can convey detailed supplementary information. Therefore, there is a high need for the NST summary, and publication of NST summaries for the appropriate cases must continue.
High level waste storage tanks 242-A evaporator S/RID phase II assessment report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Biebesheimer, E.
This document, the Standards/Requirements Identification Document (S/RID) Phase 2 Assessment Report for the subject facility, represents the results of a Performance Assessment to determine whether procedures containing S/RID requirements are fully implemented by field personnel in the field. It contains a summary report and three attachments; an assessment schedule, performance objectives, and assessments for selected functional areas.
Scheduling language and algorithm development study. Appendix: Study approach and activity summary
NASA Technical Reports Server (NTRS)
1974-01-01
The approach and organization of the study to develop a high level computer programming language and a program library are presented. The algorithm and problem modeling analyses are summarized. The approach used to identify and specify the capabilities required in the basic language is described. Results of the analyses used to define specifications for the scheduling module library are presented.
ERIC Educational Resources Information Center
Spain, William H.; Sharpe, Dennis B.
The study of Youth Transition into the Labour Market (YTLM) began several years ago in the spring of 1987. The project consists of two parallel yet interrelated studies, one focusing on the full cohort of approximately 9000 Level III high school students in Newfoundland and Labrador at the end of the 1988-89 school year, and a second, which…
Classification of occupational activity categories using accelerometry: NHANES 2003-2004.
Steeves, Jeremy A; Tudor-Locke, Catrine; Murphy, Rachel A; King, George A; Fitzhugh, Eugene C; Harris, Tamara B
2015-06-30
An individual's occupational activity (OA) may contribute significantly to daily physical activity (PA) and sedentary behavior (SB). However, there is little consensus about which occupational categories involve high OA or low OA, and the majority of categories are unclassifiable with current methods. The purpose of this study was to present population estimates of accelerometer-derived PA and SB variables for adults (n = 1112, 20-60 years) working the 40 occupational categories collected during the 2003-2004 National Health and Nutrition Examination Survey (NHANES). ActiGraph accelerometer-derived total activity counts/day (TAC), activity counts/minute, and proportion of wear time spent in moderate-to-vigorous PA [MVPA], lifestyle, and light PA organized by occupational category were ranked in ascending order and SB was ranked in descending order. Summing the ranks of the six accelerometer-derived variables generated a summary score for each occupational category, which was re-ranked in ascending order. Higher rankings indicated higher levels of OA, lower rankings indicated lower levels of OA. Tertiles of the summary score were used to establish three mutually exclusive accelerometer-determined OA groupings: high OA, intermediate OA, and low OA. According to their summary score, 'farm and nursery workers' were classified as high OA and 'secretaries, stenographers, and typists' were classified as low OA. Consistent with previous research, some low OA occupational categories (e.g., 'engineers, architects, and scientists', 'technicians and related support occupations', 'management related occupations', 'executives, administrators, and managers', 'protective services', and 'writers, artists, entertainers, and athletes') associated with higher education and income had relatively greater amounts of MVPA compared to other low OA occupational categories, likely due to the greater percentage of men in those occupations and/or the influence of higher levels of leisure time PA. Men had more TAC, activity counts/minute and time in MVPA, but similar proportions of SB compared to women in all three OA groupings. Objectively measured PA allowed for a more precise estimate of the amount of PA and SB associated with different occupations and facilitated systematic classification of the 40 different occupational categories into three distinct OA groupings. This information provides new opportunities to explore the relationship between OA and health outcomes.
A high-performance Fortran code to calculate spin- and parity-dependent nuclear level densities
NASA Astrophysics Data System (ADS)
Sen'kov, R. A.; Horoi, M.; Zelevinsky, V. G.
2013-01-01
A high-performance Fortran code is developed to calculate the spin- and parity-dependent shell model nuclear level densities. The algorithm is based on the extension of methods of statistical spectroscopy and implies exact calculation of the first and second Hamiltonian moments for different configurations at fixed spin and parity. The proton-neutron formalism is used. We have applied the method for calculating the level densities for a set of nuclei in the sd-, pf-, and pf+g- model spaces. Examples of the calculations for 28Si (in the sd-model space) and 64Ge (in the pf+g-model space) are presented. To illustrate the power of the method we estimate the ground state energy of 64Ge in the larger model space pf+g, which is not accessible to direct shell model diagonalization due to the prohibitively large dimension, by comparing with the nuclear level densities at low excitation energy calculated in the smaller model space pf. Program summaryProgram title: MM Catalogue identifier: AENM_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AENM_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 193181 No. of bytes in distributed program, including test data, etc.: 1298585 Distribution format: tar.gz Programming language: Fortran 90, MPI. Computer: Any architecture with a Fortran 90 compiler and MPI. Operating system: Linux. RAM: Proportional to the system size, in our examples, up to 75Mb Classification: 17.15. External routines: MPICH2 (http://www.mcs.anl.gov/research/projects/mpich2/) Nature of problem: Calculating of the spin- and parity-dependent nuclear level density. Solution method: The algorithm implies exact calculation of the first and second Hamiltonian moments for different configurations at fixed spin and parity. The code is parallelized using the Message Passing Interface and a master-slaves dynamical load-balancing approach. Restrictions: The program uses two-body interaction in a restricted single-level basis. For example, GXPF1A in the pf-valence space. Running time: Depends on the system size and the number of processors used (from 1 min to several hours).
XMDS2: Fast, scalable simulation of coupled stochastic partial differential equations
NASA Astrophysics Data System (ADS)
Dennis, Graham R.; Hope, Joseph J.; Johnsson, Mattias T.
2013-01-01
XMDS2 is a cross-platform, GPL-licensed, open source package for numerically integrating initial value problems that range from a single ordinary differential equation up to systems of coupled stochastic partial differential equations. The equations are described in a high-level XML-based script, and the package generates low-level optionally parallelised C++ code for the efficient solution of those equations. It combines the advantages of high-level simulations, namely fast and low-error development, with the speed, portability and scalability of hand-written code. XMDS2 is a complete redesign of the XMDS package, and features support for a much wider problem space while also producing faster code. Program summaryProgram title: XMDS2 Catalogue identifier: AENK_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AENK_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU General Public License, version 2 No. of lines in distributed program, including test data, etc.: 872490 No. of bytes in distributed program, including test data, etc.: 45522370 Distribution format: tar.gz Programming language: Python and C++. Computer: Any computer with a Unix-like system, a C++ compiler and Python. Operating system: Any Unix-like system; developed under Mac OS X and GNU/Linux. RAM: Problem dependent (roughly 50 bytes per grid point) Classification: 4.3, 6.5. External routines: The external libraries required are problem-dependent. Uses FFTW3 Fourier transforms (used only for FFT-based spectral methods), dSFMT random number generation (used only for stochastic problems), MPI message-passing interface (used only for distributed problems), HDF5, GNU Scientific Library (used only for Bessel-based spectral methods) and a BLAS implementation (used only for non-FFT-based spectral methods). Nature of problem: General coupled initial-value stochastic partial differential equations. Solution method: Spectral method with method-of-lines integration Running time: Determined by the size of the problem
Niedo, Jasmin; Tanimoto, Steve; Thompson, Robert H.; Abbott, Robert D.; Berninger, Virginia W.
2016-01-01
Students in grades 5 to 9 (ages 10 to 14; 6 girls, 27 boys) who had persisting specific learning disabilities in transcription (handwriting and spelling) completed three kinds of composition tasks requiring translation (thought to written language) on iPads using alternating transcription modes (stylus or keyboard) across every three lessons: personal narratives (6 lessons) and written summaries about read source material (integrated reading-writing) and heard source material (integrated listening-writing) (12 lessons). Before composing summaries, students clicked sequentially one at a time onto translation strategies, which they read and heard through earphones, and could click on again as needed during summary writing: (a) Level I composing of the very next sentence, and (b) Level II composing of a higher-level discourse structure. ANOVAs showed that Level I strategies were used significantly more often than Level II strategies; but the main effect for transcription mode was not significant. Written summaries of read source material had more errors in main ideas and factual details than heard source materials, but not more irrelevant statements. Applications of results are discussed for using computers for writing instruction, not just accommodations, for students with persisting transcription disabilities. PMID:28670103
Effect of high fluoride and high fat on serum lipid levels and oxidative stress in rabbits.
Sun, Liyan; Gao, Yanhui; Zhang, Wei; Liu, Hui; Sun, Dianjun
2014-11-01
The purpose of this study was to explore the effects of high fluoride and high fat on triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), total antioxidant capacity (T-AOC), lipid peroxide (LPO) and malondialdehyde (MDA) in rabbits. A factorial experimental design was used, with two factors (fluoride and fat) and three levels. Seventy-two male rabbits were randomly assigned into nine groups according to initial weight and serum lipid levels. The rabbits were fed with basic feed, moderate fat feed or high fat feed and drank tap water, fluoridated water at levels of 50 and 100mgfluorion/L freely. Biological materials were collected after 5 months, and serum lipid, T-AOC, LPO, and MDA levels were then measured. Using these data, the separate and interactive effects of high fluoride and high fat were analyzed. High fluoride and high fat both increased serum levels of TC, HDL-C and LDL-C significantly (P<0.05), and there was also a synergistic effect between high fluoride and high fat (P<0.05). High fluoride and high fat had different effects on TG levels: high fat significantly increased TG levels (P<0.01) whereas high fluoride had nothing to do with TG levels (P>0.05). High fat significantly elevated LPO and MDA levels and lowered T-AOC levels in serum (P<0.05). Similarly, high fluoride significantly increased LPO and MDA levels in serum (P<0.05). However, there was no interactive effect between high fat and high fluoride on these indexes. In summary, high fluoride and high fat increased serum TC and LDL-C levels individually and synergistically, and this would cause and aggravate hypercholesterolemia in rabbits. At the same time, high fluoride and high fat both made the accumulation of product of oxidative stress in experimental animals. Copyright © 2014 Elsevier B.V. All rights reserved.
78 FR 34978 - Amendment to Notice of Funding Availability for the Rural Energy for America Program
Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-11
... reflect these changes in program level funding, the Agency is amending the funding levels and dollars..., 2013, Notice. This Notice makes no other changes to the March 29, 2013, Notice. The following Summary of Changes apply to the March 29, 2013, Notice. Summary of Changes 1. In the third column on page...
Ocean Drilling Program: Completed Legs
. Austin Leg summary Repository Wolfgang Schlager 102 14-Mar-85 25-Apr-85 Miami, Florida 418 Bermuda Rise Lisbon, Portugal 902-906 New Jersey Sea-Level Transect Peter Blum Gregory Mountain Leg summary Repository , Nova Scotia 1071-1073 Continuing the New Jersey Sea-Level Transect Mitchell J. Malone James A. Austin
The Ideal Hospital Discharge Summary: A Survey of U.S. Physicians.
Sorita, Atsushi; Robelia, Paul M; Kattel, Sharma B; McCoy, Christopher P; Keller, Allan Scott; Almasri, Jehad; Murad, Mohammad Hassan; Newman, James S; Kashiwagi, Deanne T
2017-09-06
Hospital discharge summaries enable communication between inpatient and outpatient physicians. Despite existing guidelines for discharge summaries, they are frequently suboptimal. The aim of this study was to assess physicians' perspectives about discharge summaries and the differences between summaries' authors (hospitalists) and readers (primary care physicians [PCPs]). A national survey of 1600 U.S. physicians was undertaken. Primary measures included physicians' preferences in discharge summary standardization, content, format, and audience. A total of 815 physicians responded (response rate = 51%). Eighty-nine percent agreed that discharge summaries "should have a standardized format." Most agreed that summaries should "document everything that was done, found, and recommended in the hospital" (64%) yet "only include details that are highly pertinent to the hospitalization" (66%). Although 74% perceived patients as an important audience of discharge summaries, only 43% agreed that summaries "should be written in language that patients…can easily understand," and 68% agreed that it "should be written solely for provider-to-provider communication." Compared with hospitalists, PCPs preferred comprehensive summaries (68% versus 59%, P = 0.002). More PCPs agreed that separate summaries should be created for patients and for provider-to-provider communication than hospitalists (60% versus 47%, P < 0.001). Compared with PCPs, more hospitalists believe that "hospitalists are too busy to prepare a high-quality discharge summary" (44% versus 23%, P < 0.001) and "PCPs have insufficient time to read an entire discharge summary" (60% versus 38%, P < 0.001). Physicians believe that discharge summaries should have a standardized format but do not agree on how comprehensive or in what format they should be. Efforts are necessary to build consensus toward the ideal discharge summary.
Zhang, Han; Wheeler, William; Hyland, Paula L; Yang, Yifan; Shi, Jianxin; Chatterjee, Nilanjan; Yu, Kai
2016-06-01
Meta-analysis of multiple genome-wide association studies (GWAS) has become an effective approach for detecting single nucleotide polymorphism (SNP) associations with complex traits. However, it is difficult to integrate the readily accessible SNP-level summary statistics from a meta-analysis into more powerful multi-marker testing procedures, which generally require individual-level genetic data. We developed a general procedure called Summary based Adaptive Rank Truncated Product (sARTP) for conducting gene and pathway meta-analysis that uses only SNP-level summary statistics in combination with genotype correlation estimated from a panel of individual-level genetic data. We demonstrated the validity and power advantage of sARTP through empirical and simulated data. We conducted a comprehensive pathway-based meta-analysis with sARTP on type 2 diabetes (T2D) by integrating SNP-level summary statistics from two large studies consisting of 19,809 T2D cases and 111,181 controls with European ancestry. Among 4,713 candidate pathways from which genes in neighborhoods of 170 GWAS established T2D loci were excluded, we detected 43 T2D globally significant pathways (with Bonferroni corrected p-values < 0.05), which included the insulin signaling pathway and T2D pathway defined by KEGG, as well as the pathways defined according to specific gene expression patterns on pancreatic adenocarcinoma, hepatocellular carcinoma, and bladder carcinoma. Using summary data from 8 eastern Asian T2D GWAS with 6,952 cases and 11,865 controls, we showed 7 out of the 43 pathways identified in European populations remained to be significant in eastern Asians at the false discovery rate of 0.1. We created an R package and a web-based tool for sARTP with the capability to analyze pathways with thousands of genes and tens of thousands of SNPs.
Zhang, Han; Wheeler, William; Hyland, Paula L.; Yang, Yifan; Shi, Jianxin; Chatterjee, Nilanjan; Yu, Kai
2016-01-01
Meta-analysis of multiple genome-wide association studies (GWAS) has become an effective approach for detecting single nucleotide polymorphism (SNP) associations with complex traits. However, it is difficult to integrate the readily accessible SNP-level summary statistics from a meta-analysis into more powerful multi-marker testing procedures, which generally require individual-level genetic data. We developed a general procedure called Summary based Adaptive Rank Truncated Product (sARTP) for conducting gene and pathway meta-analysis that uses only SNP-level summary statistics in combination with genotype correlation estimated from a panel of individual-level genetic data. We demonstrated the validity and power advantage of sARTP through empirical and simulated data. We conducted a comprehensive pathway-based meta-analysis with sARTP on type 2 diabetes (T2D) by integrating SNP-level summary statistics from two large studies consisting of 19,809 T2D cases and 111,181 controls with European ancestry. Among 4,713 candidate pathways from which genes in neighborhoods of 170 GWAS established T2D loci were excluded, we detected 43 T2D globally significant pathways (with Bonferroni corrected p-values < 0.05), which included the insulin signaling pathway and T2D pathway defined by KEGG, as well as the pathways defined according to specific gene expression patterns on pancreatic adenocarcinoma, hepatocellular carcinoma, and bladder carcinoma. Using summary data from 8 eastern Asian T2D GWAS with 6,952 cases and 11,865 controls, we showed 7 out of the 43 pathways identified in European populations remained to be significant in eastern Asians at the false discovery rate of 0.1. We created an R package and a web-based tool for sARTP with the capability to analyze pathways with thousands of genes and tens of thousands of SNPs. PMID:27362418
Alternative Methods of Base Level Demand Forecasting for Economic Order Quantity Items,
1975-12-01
Note .. . . . . . . . . . . . . . . . . . . . . . . . 21 AdaptivC Single Exponential Smooti-ing ........ 21 Choosing the Smoothiing Constant... methodology used in the study, an analysis of results, .And a detailed summary. Chapter I. Methodology , contains a description o the data, a...Chapter IV. Detailed Summary, presents a detailed summary of the findings, lists the limitations inherent in the 7’" research methodology , and
ERIC Educational Resources Information Center
Hill, Sheri L.; Malhotra, Sumit; De Wys, Shelley; Mandell, Dorothy J.; Brandon, Richard
These 43 Kids Count summaries, one for each of the state's counties, major metropolitan areas, and the state as a whole, examine trends in the well-being of Washington's children. The summaries each reiterate key statewide trends in the areas of education, child maltreatment, housing affordability, and employment levels, as well as family…
Summary of Policies: What the Association Thinks To Help You Plan, Teach, Negotiate, Manage.
ERIC Educational Resources Information Center
Association for Science Education, Herts (England).
This document contains a summary of the policies adopted by the Association for Science Education (ASE). These policies are applicable to teachers of science at all levels in all formal places of learning in Great Britain. Summaries of policy statements pertaining to quality in science education, a flowchart that provides an overview of these…
FT4 Data Analysis Summary (SSI-ARC)
NASA Technical Reports Server (NTRS)
Isaacson, Douglas R.; Gong, Chester; Reardon, Scott Edward; Santiago, Confesor
2016-01-01
Standards for Unmanned Aircraft System (UAS) Detect-and-Avoid (DAA) systems are currently being developed under the auspices of the RTCA Special Committee 228 (SC-228). To support the development of these standards, a series of flight tests has been conducted at NASAs Armstrong Flight Research Center (NASA-AFRC). The fourth in this series of flight test activities (Flight Test 4, or simply FT4) was conducted during the Spring and Summer of 2016. FT4 supported the objectives of numerous organizations working toward UAS DAA Minimum Operational Performance Standards (MOPS) and UAS DAA Radar MOPS. The summary provided herein is limited to the objectives, analysis and conclusions of the NASA Ames Research Center (NASA-ARC) SSI team toward the refinement of UAS DAA MOPS. This document provides a high-level overview of FT4 and the SSI-ARC objectives, a summary of the data analysis methodology and recommendations for UAS DAA MOPS refinements based on the data analysis results. A total of 72 encounters were flown to support SSI-ARC objectives. Test results were generally consistent with acceptable UAS DAA system performance and will be considered in broader SC-228 requirements validation efforts. Observed alert lead times indicated acceptable UAS DAA alerting performance. Effective interoperability between the UAS DAA system and the Traffic Alert and Collision Avoidance System (TCAS) was observed with one notable exception: TCAS Resolutions Advisories (RA) were observed in the absence of any DAA alert on two occasions, indicating the need for alert parameter refinement. Findings further indicated the need for continued work in the areas of DAA Well Clear Recovery logic and alert stability for Mode-C-only intruders. Finally, results demonstrated a high level of compliance with a set of evaluation criteria designed to provide anecdotal evidence of acceptable UAS DAA system performance.
Civil tiltrotor missions and applications
NASA Technical Reports Server (NTRS)
Clay, Bill; Baumgaertner, Paul; Thompson, Pete; Meyer, Sam; Reber, Ron; Berry, Dennis (Editor)
1987-01-01
In 1983, an FAA-sponsored National Rotorcraft Program sought to identify improvements to the national interurban transportation networks and determined that conventional helicopters did not have the potential to satisfy requirements because of a lack of capacity, high operational costs, and high noise levels. Tiltrotors, it was felt offered a better potential to improve interurban air transport service. In 1985, the FAA proposed a joint civil tiltrotor study with NASA and DOD that would capitalize on development of the military V-22 tiltrotor and document the potential of the commercial tiltrotor transport market. The results of a study on the mission and application of a civil tiltrotor is presented. This study addresses national issues and includes a market summary. A technical summary provides information on six design configurations and potential risk areas are identified. The development of a National Plan for a tiltrotor transportation system is recommended including civil tiltrotor technology development, infrastructure planning and development, a flight technology demonstration plan, and near term actions.
User Guide for State Summaries
The EPA developed state-level summaries of chemical and water use using the project database developed from FracFocus 1.0 disclosures with some limited background information on oil and gas production, geology, and regulations for the state.
ERIC Educational Resources Information Center
Charbonneau, Gary; And Others
This paper describes some of the problems encountered and the resolutions reached in converting Indiana University Libraries serials holdings information to the format specified in the 1980 American National Standard for Serial Holdings Statements at the Summary Level (ANSI). It is noted that this project was part of the development--by OCLC--of…
The Republic of the Philippines: Background and U.S. Relations
2009-01-15
President Noli de Catro; former Senate President Manuel B. Villar (Nacionalista Party); Senator Loren Legarda (Genuine Opposition coalition), and Senator... Manuel “Mar” Roxas II (Liberal Party).7 On the one hand, RP citizens enjoy a high level of political freedom, including a robust civil society, while...Special Rapporteur on Extrajudicial, Summary or Arbitrary Executions, Philip Alston, to conduct a fact- finding mission. The task force ( Melo Commission
System-Level Experimentation: Executive Summary and Annotated Brief
2006-07-01
both friendlies and adversaries – to define their own capabilities, unfettered by doctrinal or cultural limitations and bounded only by the laws of...Gen Eric Nelson, USAF (Ret) Independent Consultant (Systems, Software) Dr. Brad Parkinson Stanford University (GPS, Sensors, Systems) Mr. Skip Saunders...RCO* – rapid fielding for high priority needs SLE is focused on understanding the future - unknown needs A8’ s Future Game – analysis of future
ERIC Educational Resources Information Center
Bureau of Labor Statistics, Washington, DC.
The Bureau of Labor Statistics projects national employment to grow by almost 26.4 million over the 1992-2005 period. The majority of these new jobs will be in higher-paying occupations. Entry requirements of the new jobs in occupations having above-average earnings will range from no more than a high school education to a bachelor's degree or…
2008-10-01
advanced materials, US producers still have a reservoir of intellectual property , product capabilities and process know-how built over several...while providing remarkable properties superior to conventional materials (ultra lightweight, high strength and stiffness). Characteristics of these...investor and tax environment; and • A level playing field, with enforcement of trade agreements and intellectual property (IP) rights. Accordingly, the
Computer architecture evaluation for structural dynamics computations: Project summary
NASA Technical Reports Server (NTRS)
Standley, Hilda M.
1989-01-01
The intent of the proposed effort is the examination of the impact of the elements of parallel architectures on the performance realized in a parallel computation. To this end, three major projects are developed: a language for the expression of high level parallelism, a statistical technique for the synthesis of multicomputer interconnection networks based upon performance prediction, and a queueing model for the analysis of shared memory hierarchies.
ERIC Educational Resources Information Center
Hoffman, Nancy
2015-01-01
In the United States, we tend to assume that young people should become educated and then go to work, as though the two were entirely separate stages of life. This dichotomy blinds us to the fact that work itself can be a powerful means of education. Indeed, the workplace is where many young people become most engaged in learning high-level skills…
Space Shuttle program orbital flight test program results and implications
NASA Technical Reports Server (NTRS)
Kohrs, R. H.
1982-01-01
The Space Shuttle System Orbital Flight Test (OFT) program results are described along with an overview of significant development issues and their resolution. In addition, an overall summary of the development status and the follow-on flight demonstrations of Shuttle improvements such as Lightweight External Tank, High Performance SRBs, Full Power Level (109%) Main Engine Operation, and the SRB Filament Wound Case (FWC) will be discussed.
Diet and caries experience among preschool children in Ajman, United Arab Emirates.
Hashim, Raghad; Williams, Sheila M; Murray Thomson, Williams
2009-12-01
The study investigated the association between food and drink consumption and the caries experience among young children in Ajman, United Arab Emirates. A one-stage cluster sample was used to select children who were 5 or 6 yr of age. Clinical examinations for caries were conducted. Parents completed questionnaires seeking information on dietary habits. Principal components analysis was used to derive a summary score for the dietary variables (designated 'snack consumption level') and thus overcome the multicollinearity problems associated with using multiple dietary variables. Dental examination and questionnaire data were obtained for 1,036 children (79.9% participation rate). The overall mean number of decayed, missing or filled teeth (dmft) was 4.5. Snacking three or more times per day was associated with a dmft score that was almost one-third higher than the dmft score for children who snacked only once daily. One-third of children had a low overall snack consumption level (41% moderate and 25% high). There was a consistent dmft gradient across those categories. The severity of Early Childhood Caries (ECC) in young Ajman children is high, with dietary habits being important determinants. Cariogenic snack consumption can be represented using a summary exposure variable that appears to be valid. Young children in Ajman would benefit from health-promotion strategies directed towards appropriate dietary practices.
NASA Technical Reports Server (NTRS)
1992-01-01
The status is summarized of the NASA sponsored involvement in high speed civil transport research and technology, including major cooperative efforts. That involvement is currently focussed on the High Speed Research Program. The program goals are an acceptable level of ozone depletion or sonic boom, the definition of which is a regulatory and political process. The HSRP goal is to provide technical bases for acceptability criteria. Community noise is currently regulated, and it seems clear that HSCT aircraft will have to comply with at least the spirit of the current subsonic constraint, FAR 36, Stage 3.
What Roles and Missions for Europe’s Military and Security Forces in the 21st Century?
2005-08-01
Studies Dr. John L. Clarke vi Executive Summary Are armies the dinosaurs of the 21st Century, soon to become extinct in the new security environment? What...and 40-year old weapons systems. Dr. John L. Clarke 6 For many reasons , Europe’s armed forces are in a long-term period of decline, and this trend is...in a reasonable period of time and on a high level of interoperability. The capability of carrying out sophisticated operations with a high operational
2016 Service Academy Gender Relations Survey: Overview Report
2017-02-01
environment within the Academies. This Executive Summary will provide a summary of the methodology used and the top line results from the survey.1 Summary...discussion of the measurement constructs, a description of the survey methodology , and detailed presentation of the results. Each report section...are determined statistically significant at an alpha (α) level of .05.6 Survey Methodology Statistical Design OPA conducts cross-Service surveys that
Tillery, Anne
2008-01-01
The Southern High Plains aquifer is the principal aquifer in Curry and Roosevelt Counties, N. Mex., and primary source of water in southeastern New Mexico. Successful water-supply planning for New Mexico's Southern High Plains requires knowledge of the current aquifer conditions and a context to estimate future trends given current aquifer-management policy. This report provides a summary of the current (2007) water-level status of the Southern High Plains aquifer in New Mexico, including a basis for estimating future trends by comparison with historical conditions. This report includes estimates of the extent of ground-water level declines in the Curry County, Portales, and Causey-Lingo Ground-water Management Area parts of the High Plains Aquifer in eastern New Mexico since predevelopment. Maps representing 2007 water levels, water-level declines, aquifer saturated thickness, and depth to water accompanied by hydrographs from representative wells for the Southern High Plains aquifer in the Curry County, Portales, and Causey Lingo Underground Water Basins were prepared in cooperation with the New Mexico Office of the State Engineer. The results of this mapping show the water level declined as much as 175 feet in the study area at rates as high as 1.76 feet per year.
Airport noise summary, 2000-2002
DOT National Transportation Integrated Search
2002-01-01
This 20002002 edition of the NBAA Airport Noise Summary : shows those airports with noise advisories or rules. These restrictions : range from a simple avoid overflight of school 2 NM south of 09 : approach to a specific decibel level requir...
LevelScheme: A level scheme drawing and scientific figure preparation system for Mathematica
NASA Astrophysics Data System (ADS)
Caprio, M. A.
2005-09-01
LevelScheme is a scientific figure preparation system for Mathematica. The main emphasis is upon the construction of level schemes, or level energy diagrams, as used in nuclear, atomic, molecular, and hadronic physics. LevelScheme also provides a general infrastructure for the preparation of publication-quality figures, including support for multipanel and inset plotting, customizable tick mark generation, and various drawing and labeling tasks. Coupled with Mathematica's plotting functions and powerful programming language, LevelScheme provides a flexible system for the creation of figures combining diagrams, mathematical plots, and data plots. Program summaryTitle of program:LevelScheme Catalogue identifier:ADVZ Program obtainable from: CPC Program Library, Queen's University of Belfast, N. Ireland Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADVZ Operating systems:Any which supports Mathematica; tested under Microsoft Windows XP, Macintosh OS X, and Linux Programming language used:Mathematica 4 Number of bytes in distributed program, including test and documentation:3 051 807 Distribution format:tar.gz Nature of problem:Creation of level scheme diagrams. Creation of publication-quality multipart figures incorporating diagrams and plots. Method of solution:A set of Mathematica packages has been developed, providing a library of level scheme drawing objects, tools for figure construction and labeling, and control code for producing the graphics.
La Camera, Richard J.; Locke, Glenn L.; Habte, Aron M.; Darnell, Jon G.
2006-01-01
The U.S. Geological Survey, in support of the U.S. Department of Energy, Office of Repository Development, collects, compiles, and summarizes hydrologic data in the Yucca Mountain region of southern Nevada and eastern California. These data are collected to allow assessments of ground-water resources during activities to determine the potential suitability or development of Yucca Mountain for storing high-level nuclear waste. Data on ground-water levels at 35 boreholes and 1 fissure (Devils Hole), ground-water discharge at 5 springs, both ground-water levels and discharge at 1 flowing borehole, and total reported ground-water withdrawals within Crater Flat, Jackass Flats, Mercury Valley, and the Amargosa Desert are tabulated from January through December 2004. Also tabulated are ground-water levels, discharges, and withdrawals collected by other agencies (or collected as part of other programs) and data revised from those previously published at monitoring sites. Historical data on water levels, discharges, and withdrawals are presented graphically to indicate variations through time. A statistical summary of ground-water levels at seven boreholes in Jackass Flats is presented for the period 1992-2004 to indicate potential effects of ground-water withdrawals associated with U.S. Department of Energy activities near Yucca Mountain. The statistical summary includes the annual number of measurements, maximum, minimum, and median water-level altitudes, and average deviation of measured water-level altitudes compared to the 1992-93 baseline period. At six boreholes in Jackass Flats, median water levels for 2004 were slightly higher (0.3-2.7 feet) than their median water levels for 1992-93. At one borehole in Jackass Flats, median water level for 2004 equaled the median water level for 1992-93.
DISSCO: direct imputation of summary statistics allowing covariates
Xu, Zheng; Duan, Qing; Yan, Song; Chen, Wei; Li, Mingyao; Lange, Ethan; Li, Yun
2015-01-01
Background: Imputation of individual level genotypes at untyped markers using an external reference panel of genotyped or sequenced individuals has become standard practice in genetic association studies. Direct imputation of summary statistics can also be valuable, for example in meta-analyses where individual level genotype data are not available. Two methods (DIST and ImpG-Summary/LD), that assume a multivariate Gaussian distribution for the association summary statistics, have been proposed for imputing association summary statistics. However, both methods assume that the correlations between association summary statistics are the same as the correlations between the corresponding genotypes. This assumption can be violated in the presence of confounding covariates. Methods: We analytically show that in the absence of covariates, correlation among association summary statistics is indeed the same as that among the corresponding genotypes, thus serving as a theoretical justification for the recently proposed methods. We continue to prove that in the presence of covariates, correlation among association summary statistics becomes the partial correlation of the corresponding genotypes controlling for covariates. We therefore develop direct imputation of summary statistics allowing covariates (DISSCO). Results: We consider two real-life scenarios where the correlation and partial correlation likely make practical difference: (i) association studies in admixed populations; (ii) association studies in presence of other confounding covariate(s). Application of DISSCO to real datasets under both scenarios shows at least comparable, if not better, performance compared with existing correlation-based methods, particularly for lower frequency variants. For example, DISSCO can reduce the absolute deviation from the truth by 3.9–15.2% for variants with minor allele frequency <5%. Availability and implementation: http://www.unc.edu/∼yunmli/DISSCO. Contact: yunli@med.unc.edu Supplementary information: Supplementary data are available at Bioinformatics online. PMID:25810429
DISSCO: direct imputation of summary statistics allowing covariates.
Xu, Zheng; Duan, Qing; Yan, Song; Chen, Wei; Li, Mingyao; Lange, Ethan; Li, Yun
2015-08-01
Imputation of individual level genotypes at untyped markers using an external reference panel of genotyped or sequenced individuals has become standard practice in genetic association studies. Direct imputation of summary statistics can also be valuable, for example in meta-analyses where individual level genotype data are not available. Two methods (DIST and ImpG-Summary/LD), that assume a multivariate Gaussian distribution for the association summary statistics, have been proposed for imputing association summary statistics. However, both methods assume that the correlations between association summary statistics are the same as the correlations between the corresponding genotypes. This assumption can be violated in the presence of confounding covariates. We analytically show that in the absence of covariates, correlation among association summary statistics is indeed the same as that among the corresponding genotypes, thus serving as a theoretical justification for the recently proposed methods. We continue to prove that in the presence of covariates, correlation among association summary statistics becomes the partial correlation of the corresponding genotypes controlling for covariates. We therefore develop direct imputation of summary statistics allowing covariates (DISSCO). We consider two real-life scenarios where the correlation and partial correlation likely make practical difference: (i) association studies in admixed populations; (ii) association studies in presence of other confounding covariate(s). Application of DISSCO to real datasets under both scenarios shows at least comparable, if not better, performance compared with existing correlation-based methods, particularly for lower frequency variants. For example, DISSCO can reduce the absolute deviation from the truth by 3.9-15.2% for variants with minor allele frequency <5%. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
An Adaptive Association Test for Multiple Phenotypes with GWAS Summary Statistics.
Kim, Junghi; Bai, Yun; Pan, Wei
2015-12-01
We study the problem of testing for single marker-multiple phenotype associations based on genome-wide association study (GWAS) summary statistics without access to individual-level genotype and phenotype data. For most published GWASs, because obtaining summary data is substantially easier than accessing individual-level phenotype and genotype data, while often multiple correlated traits have been collected, the problem studied here has become increasingly important. We propose a powerful adaptive test and compare its performance with some existing tests. We illustrate its applications to analyses of a meta-analyzed GWAS dataset with three blood lipid traits and another with sex-stratified anthropometric traits, and further demonstrate its potential power gain over some existing methods through realistic simulation studies. We start from the situation with only one set of (possibly meta-analyzed) genome-wide summary statistics, then extend the method to meta-analysis of multiple sets of genome-wide summary statistics, each from one GWAS. We expect the proposed test to be useful in practice as more powerful than or complementary to existing methods. © 2015 WILEY PERIODICALS, INC.
Compilation of current high energy physics experiments - Sept. 1978
DOE Office of Scientific and Technical Information (OSTI.GOV)
Addis, L.; Odian, A.; Row, G. M.
1978-09-01
This compilation of current high-energy physics experiments is a collaborative effort of the Berkeley Particle Data Group, the SLAC library, and the nine participating laboratories: Argonne (ANL), Brookhaven (BNL), CERN, DESY, Fermilab (FNAL), KEK, Rutherford (RHEL), Serpukhov (SERP), and SLAC. Nominally, the compilation includes summaries of all high-energy physics experiments at the above laboratories that were approved (and not subsequently withdrawn) before about June 1978, and had not completed taking of data by 1 January 1975. The experimental summaries are supplemented with three indexes to the compilation, several vocabulary lists giving names or abbreviations used, and a short summary ofmore » the beams at each of the laboratories (except Rutherford). The summaries themselves are included on microfiche. (RWR)« less
Renewable Electricity Futures Study. Executive Summary
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mai, T.; Sandor, D.; Wiser, R.
2012-12-01
The Renewable Electricity Futures (RE Futures) Study investigated the challenges and impacts of achieving very high renewable electricity generation levels in the contiguous United States by 2050. The analysis focused on the sufficiency of the geographically diverse U.S. renewable resources to meet electricity demand over future decades, the hourly operational characteristics of the U.S. grid with high levels of variable wind and solar generation, and the potential implications of deploying high levels of renewables in the future. RE Futures focused on technical aspects of high penetration of renewable electricity; it did not focus on how to achieve such a futuremore » through policy or other measures. Given the inherent uncertainties involved with analyzing alternative long-term energy futures as well as the multiple pathways that might be taken to achieve higher levels of renewable electricity supply, RE Futures explored a range of scenarios to investigate and compare the impacts of renewable electricity penetration levels (30%-90%), future technology performance improvements, potential constraints to renewable electricity development, and future electricity demand growth assumptions. RE Futures was led by the National Renewable Energy Laboratory (NREL) and the Massachusetts Institute of Technology (MIT).« less
La Camera, Richard J.; Westenburg, Craig L.
1994-01-01
Tne U.S. Geological Survey. in support of the U.S. Department of Energy, Yucca Mountain Site- Characterization Project, collects, compiles, and summarizes water-resource data in the Yucca Mountain region. The data are collected to document the historical and current condition of ground-water resources, to detect and document changes in those resources through time, and to allow assessments of ground-water resources during investigations to determine the potential suitability of Yucca Mountain for storing high-level nuclear waste. Data on ground-water levels at 36 sites, ground- water discharge at 6 sites, ground-water quality at 19 sites, and ground-water withdrawals within Crater Fiat, Jackass Flats, Mercury Valley, and the Amargosa Desert are presented. Data on ground-water levels, discharges, and withdrawals collected by other agencies or as part of other programs are included to further indicate variations through time. A statistical summary of ground-water levels and median annual ground-water withdrawals in Jackass Flats is presented. The statistical summary includes the number of measurements, the maximum, minimum, and median water-level altitudes, and the average deviation of a11 water-level altitudes for selected baseline periods and for calendar year 1992. Data on ground-water quality are compared to established, proposed, or tentative primary and secondary drinking-water standards, and measures which exceeded those standards are listed for 18 sites. Detected organic compounds for which established, proposed, or tentative drinking-water standards exist also are listed.
Locke, Glenn L.; La Camera, Richard J.
2003-01-01
The U.S. Geological Survey, in support of the U.S. Department of Energy, Yucca Mountain Project, collects, compiles, and summarizes hydrologic data in the Yucca Mountain region. The data are collected to allow assessments of ground-water resources during activities to determine the potential suitability or development of Yucca Mountain for storing high-level nuclear waste. Data on ground-water levels at 35 wells and a fissure (Devils Hole), ground-water discharge at 5 springs and a flowing well, and total reported ground-water withdrawals within Crater Flat, Jackass Flats, Mercury Valley, and the Amargosa Desert are tabulated from January 2000 through December 2002. Historical data on water levels, discharges, and withdrawals are graphically presented to indicate variations through time. A statistical summary of ground-water levels at seven wells in Jackass Flats is presented for 1992-2002 to indicate potential effects of ground-water withdrawals associated with U.S. Department of Energy activities near Yucca Mountain. The statistical summary includes the annual number of measurements, maximum, minimum, and median water-level altitudes, and average deviation of measured water-level altitudes compared to selected baseline periods. Baseline periods varied for 1985-93. At six of the seven wells in Jackass Flats, the median water levels for 2002 were slightly higher (0.3-2.4 feet) than for their respective baseline periods. At the remaining well, data for 2002 was not summarized statistically but median water-level altitude in 2001 was 0.7 foot higher than that in its baseline period.
City of Chicago Combined Work Plan and Summary Report for Loewenthal Metals
Summary of the work performed by the City’s Department of Fleet and Facility Management on behalf of the Chicago Department of Transportation (CDOT) to address elevated levels of lead in City right of way..
Third Earth Resources Technology Satellite Symposium. Volume 2: Summary of results
NASA Technical Reports Server (NTRS)
Freden, S. C. (Editor); Mercanti, E. P. (Editor); Friedman, D. B. (Editor)
1974-01-01
Summaries are provided of significant results taken from presentations at the symposium along with some typical examples of the applications of ERTS-1 data for solving resources management problems at the national, state, and local levels.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1983-09-09
This Validation Summary Report (VSR) for the Cray Research, Inc., CRAY FORTRAN Translator (CFT) Version 1.11 Bugfix 1 running under the CRAY Operating System (COS) Version 1.12 provides a consolidated summary of the results obtained from the validation of the subject compiler against the 1978 FORTRAN Standard (X3.9-1978/FIPS PUB 69). The compiler was validated against the Full Level FORTRAN level of FIPS PUB 69. The VSR is made up of several sections showing all the discrepancies found -if any. These include an overview of the validation which lists all categories of discrepancies together with the tests which failed.
Sukanya, Chongthawonsatid
2017-10-01
This study examined the validity of the principal diagnoses on discharge summaries and coding assessments. Data were collected from the National Health Security Office (NHSO) of Thailand in 2015. In total, 118,971 medical records were audited. The sample was drawn from government hospitals and private hospitals covered by the Universal Coverage Scheme in Thailand. Hospitals and cases were selected using NHSO criteria. The validity of the principal diagnoses listed in the "Summary and Coding Assessment" forms was established by comparing data from the discharge summaries with data obtained from medical record reviews, and additionally, by comparing data from the coding assessments with data in the computerized ICD (the data base used for reimbursement-purposes). The summary assessments had low sensitivities (7.3%-37.9%), high specificities (97.2%-99.8%), low positive predictive values (9.2%-60.7%), and high negative predictive values (95.9%-99.3%). The coding assessments had low sensitivities (31.1%-69.4%), high specificities (99.0%-99.9%), moderate positive predictive values (43.8%-89.0%), and high negative predictive values (97.3%-99.5%). The discharge summaries and codings often contained mistakes, particularly the categories "Endocrine, nutritional, and metabolic diseases", "Symptoms, signs, and abnormal clinical and laboratory findings not elsewhere classified", "Factors influencing health status and contact with health services", and "Injury, poisoning, and certain other consequences of external causes". The validity of the principal diagnoses on the summary and coding assessment forms was found to be low. The training of physicians and coders must be strengthened to improve the validity of discharge summaries and codings.
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1998-11-06
In support of the Weldon Spring Site Remedial Action Project Federal Facilities Agreement, a copy of the Quarterly Environmental Data Summary (QEDS) for the third quarter of 1998 is enclosed. The data presented in this letter and attachment constitute the QEDS. The data, except for air monitoring data and site KPA generated data (uranium analyses), were received from the contract laboratories, verified by the Weldon Spring Site verification group, and merged into the database during the third quarter of 1998. Air monitoring data presented are the most recent complete sets of quarterly data. Significant data, defined as data values thatmore » have exceeded defined above normal Level 2 values, are discussed in this letter for Environmental Monitoring Plan (EMP) generated data only. Above normal Level 2 values are based, in ES and H procedures, on historical high values, DOE Derived Concentration Guides (DCGs), NPDES limits, and other guidelines. The procedures also establish actions to be taken in the event that above normal data occur.« less
Duan, Q; Jiao, J; Chen, X; Wang, X
2018-01-01
Higher fluoride concentrations in water have inconsistently been associated with the levels of intelligence in children. The following study summarizes the available evidence regarding the strength of association between fluoridated water and children's intelligence. Meta-analysis. PubMed, Embase, and Cochrane Library databases were systematically analyzed from November 2016. Observational studies that have reported on intelligence levels in relation to high and low water fluoride contents, with 95% confidence intervals (CIs) were included. Further, the results were pooled using inverse variance methods. The correlation between water fluoride concentration and intelligence level was assessed by a dose-response meta-analysis. Twenty-six studies reporting data on 7258 children were included. The summary results indicated that high water fluoride exposure was associated with lower intelligence levels (standardized mean difference : -0.52; 95% CI: -0.62 to -0.42; P < 0.001). The findings from subgroup analyses were consistent with those from overall analysis. The dose-response meta-analysis suggested a significant association between water fluoride dosage and intelligence (P < 0.001), while increased water fluoride exposure was associated with reduced intelligence levels. Greater exposure to high levels of fluoride in water was significantly associated with reduced levels of intelligence in children. Therefore, water quality and exposure to fluoride in water should be controlled in areas with high fluoride levels in water. Copyright © 2017. Published by Elsevier Ltd.
Neurotox-98 Neuroprotection by Progesterones Through Stimulation of Mitochondrial Gene Expression
2006-06-01
excitotoxicity that leads to neuronal cell loss. However, surprisingly little is known of the mechanism for this effect . The working hypothesis for the...regulation that is independent of energy status of the cell . Although not included in the publication, we tested for effects of progesterone on... effects (Goodman et al., 1996); however, high levels of progesterone did nothing to protect the animals from seizures or neuronal cell death. In summary
Engine Component Retirement for Cause. Volume 1. Executive Summary
1987-08-01
components of all future engines. A mejor factor in the success of this progrm in taking Retirement for Cause from a concept to reality was the high level of...engine was chosen as the demonstration/validation vehicle for the Retirement for Cause (RCF) program. It is an augmented turbofan engine in the...inspections using surface replication; aspect ratios were determined from post test fractography . The crack size observed from the testing was compared to
International High/Scope Conference Proceedings (Ypsilanti, Michigan, May 4-7, 1999).
ERIC Educational Resources Information Center
High/Scope Educational Research Foundation, Ypsilanti, MI.
These conference proceedings provide summaries of 61 presentations on various aspects of the High/Scope educational approach. In addition to summaries of special presentations on music and movement and on preschool "basics," topics addressed include: (1) High/Scope in the secondary setting; (2) classroom environment; (3) outdoor…
ERIC Educational Resources Information Center
Carnevale, Anthony P.; Smith, Nicole; Gulish, Artem; Beach, Bennett H.
2012-01-01
This executive summary highlights several findings about healthcare. These are: (1) Healthcare is 18 percent of the U.S. economy, twice as high as in other countries; (2) There are two labor markets in healthcare: high-skill, high-wage professional and technical jobs and low-skill, low-wage support jobs; (3) Demand for postsecondary education in…
Arthroscopic treatment of chronic patellar tendinopathy in high-level athletes
Alaseirlis, Dimosthenis Artemis; Konstantinidis, George Athanasios; Malliaropoulos, Nikolaos; Nakou, Lamprini Stefanos; Korompilias, Anastasios; Maffulli, Nicola
2012-01-01
Summary To present the results of arthroscopic treatment of patellar tendinopathy in high-level competition athletes. Eleven high-level athletes presented chronic patellar tendinopathy which did not respond to long term conservative treatment. Average age of the patients was 24.8 ±3.4 years old. All patients received an arthroscopic procedure with osteoplasty of the distal patellar pole, debridement of the underlying Hoffa fat pad and of the degenerated areas of the proximal posterior patella tendon and cauterization of the visible neo-vessels. Mean duration of follow-up was 17.4±4 months. Patients showed a major improvement in the Lysholm score from 49.9±5.2 to 92.5±7 and in the VISA P score from 41.2±5.2 to 86.8±14.9 on tenth post-operative week. All patients had returned to sports activities by the twelfth postoperative week. Arthroscopic treatment of chronic patellar tendinopathy found to be a minimal invasive and safe technique which produced satisfactory results. PMID:23738308
Lovelace, Wendell M.
2002-01-01
This report presents water-level measurements and chlorideconcentrations in water from selected wells completed in aquifers in Louisiana. The data were collected during the period January1988-October 1997. Water-level data are presented for 109 wells, and chloride data are presented for 45 wells. Hydrographs and summaries of water-level trends are presented for wellscompleted in aquifers throughout the State. Chlorographs and summaries of chloride trends are presented for wells completed in the Mississippi River alluvial and Sparta aquifers; Chicot aquifer system; and Gramercy, Norco, and Gonzales-New Orleans aquifers. Data are presented in graphical and tabular formats.
Accounting for correlation in network meta-analysis with multi-arm trials.
Franchini, A J; Dias, S; Ades, A E; Jansen, J P; Welton, N J
2012-06-01
Multi-arm trials (trials with more than two arms) are particularly valuable forms of evidence for network meta-analysis (NMA). Trial results are available either as arm-level summaries, where effect measures are reported for each arm, or as contrast-level summaries, where the differences in effect between arms compare with the control arm chosen for the trial. We show that likelihood-based inference in both contrast-level and arm-level formats is identical if there are only two-arm trials, but that if there are multi-arm trials, results from the contrast-level format will be incorrect unless correlations are accounted for in the likelihood. We review Bayesian and frequentist software for NMA with multi-arm trials that can account for this correlation and give an illustrative example of the difference in estimates that can be introduced if the correlations are not incorporated. We discuss methods of imputing correlations when they cannot be derived from the reported results and urge trialists to report the standard error for the control arm even if only contrast-level summaries are reported. Copyright © 2012 John Wiley & Sons, Ltd. Copyright © 2012 John Wiley & Sons, Ltd.
NASA Astrophysics Data System (ADS)
Nawani, Jigna; Rixius, Julia; Neuhaus, Birgit J.
2016-08-01
Empirical analysis of secondary biology classrooms revealed that, on average, 68% of teaching time in Germany revolved around processing tasks. Quality of instruction can thus be assessed by analyzing the quality of tasks used in classroom discourse. This quasi-experimental study analyzed how teachers used tasks in 38 videotaped biology lessons pertaining to the topic 'blood and circulatory system'. Two fundamental characteristics used to analyze tasks include: (1) required cognitive level of processing (e.g. low level information processing: repetiition, summary, define, classify and high level information processing: interpret-analyze data, formulate hypothesis, etc.) and (2) complexity of task content (e.g. if tasks require use of factual, linking or concept level content). Additionally, students' cognitive knowledge structure about the topic 'blood and circulatory system' was measured using student-drawn concept maps (N = 970 students). Finally, linear multilevel models were created with high-level cognitive processing tasks and higher content complexity tasks as class-level predictors and students' prior knowledge, students' interest in biology, and students' interest in biology activities as control covariates. Results showed a positive influence of high-level cognitive processing tasks (β = 0.07; p < .01) on students' cognitive knowledge structure. However, there was no observed effect of higher content complexity tasks on students' cognitive knowledge structure. Presented findings encourage the use of high-level cognitive processing tasks in biology instruction.
Richards, Todd; Peverly, Stephen; Wolf, Amie; Abbott, Robert; Tanimoto, Steven; Thompson, Rob; Nagy, William; Berninger, Virginia
2016-01-01
Seven children with dyslexia and/or dysgraphia (2 girls, 5 boys, M=11 years) completed fMRI connectivity scans before and after twelve weekly computerized lessons in strategies for reading source material, taking notes, and writing summaries by touch typing or groovy pencils. During brain scanning they completed two reading comprehension tasks—one involving single sentences and one involving multiple sentences. From before to after intervention, fMRI connectivity magnitude changed significantly during sentence level reading comprehension (from right angular gyrus→right Broca’s) and during text level reading comprehension (from right angular gyrus→cingulate). Proportions of ideas units in children’s writing compared to idea units in source texts did not differ across combinations of reading-writing tasks and modes. Yet, for handwriting/notes, correlations insignificant before the lessons became significant after the strategy instruction between proportion of idea units and brain connectivity at all levels of language in reading comprehension (word-, sentence-, and text) during scanning; but for handwriting/summaries, touch typing/notes, and touch typing/summaries changes in those correlations from insignificant to significant after strategy instruction occurred only at text level reading comprehension during scanning. Thus, handwriting during note-taking may benefit all levels of language during reading comprehension, whereas all other combinations of modes and writing tasks in this exploratory study appear to benefit only the text level of reading comprehension. Neurological and educational significance of the interdisciplinary research findings for integrating reading and writing and future research directions are discussed. PMID:28133634
Richards, Todd; Peverly, Stephen; Wolf, Amie; Abbott, Robert; Tanimoto, Steven; Thompson, Rob; Nagy, William; Berninger, Virginia
2016-09-01
Seven children with dyslexia and/or dysgraphia (2 girls, 5 boys, M =11 years) completed fMRI connectivity scans before and after twelve weekly computerized lessons in strategies for reading source material, taking notes, and writing summaries by touch typing or groovy pencils. During brain scanning they completed two reading comprehension tasks-one involving single sentences and one involving multiple sentences. From before to after intervention, fMRI connectivity magnitude changed significantly during sentence level reading comprehension (from right angular gyrus→right Broca's) and during text level reading comprehension (from right angular gyrus→cingulate). Proportions of ideas units in children's writing compared to idea units in source texts did not differ across combinations of reading-writing tasks and modes. Yet, for handwriting/notes, correlations insignificant before the lessons became significant after the strategy instruction between proportion of idea units and brain connectivity at all levels of language in reading comprehension (word-, sentence-, and text) during scanning; but for handwriting/summaries, touch typing/notes, and touch typing/summaries changes in those correlations from insignificant to significant after strategy instruction occurred only at text level reading comprehension during scanning. Thus, handwriting during note-taking may benefit all levels of language during reading comprehension, whereas all other combinations of modes and writing tasks in this exploratory study appear to benefit only the text level of reading comprehension. Neurological and educational significance of the interdisciplinary research findings for integrating reading and writing and future research directions are discussed.
Locke, G.L.
2001-01-01
The U.S. Geological Survey, in support of the U.S. Department of Energy, Yucca Mountain Site Characterization Project, collects, compiles, and summarizes hydrologic data in the Yucca Mountain region. The data are collected to allow assessments of ground-water resources during studies to determine the potential suitability of Yucca Mountain for storing high-level nuclear waste. Data on ground-water levels at 34 wells and a fissure (Devils Hole), ground-water discharge at 5 springs and a flowing well, and total reported ground-water withdrawals within Crater Flat, Jackass Flats, Mercury Valley, and the Amargosa Desert are presented for calendar year 1999. Data collected prior to 1999 are graphically presented and data collected by other agencies (or as part of other Geological Survey programs) are included to further indicate variations of ground-water levels, discharges, and withdrawals through time. A statistical summary of ground-water levels at seven wells in Jackass Flats is presented to indicate potential effects of ground-water withdrawals associated with U.S. Department of Energy activities near Yucca Mountain. The statistical summary includes the number of measurements, the maximum, minimum, and median water-level altitudes, and the average deviation of measured water-level altitudes for selected baseline periods and for calendar years 1992-99. At two water-supply wells median water levels for calendar year 1999 were unchanged from their respective baseline periods. At a nearby observation well, the 1999 median water level was slightly lower (0.1 foot) than its baseline period. At the remaining four wells in Jackass Flats, median water levels for 1999 were slightly higher (0.2 foot to 1.6 feet) than for their respective baseline periods.
International High/Scope Registry Conference Proceedings (Ypsilanti, Michigan, May 7-10, 1997).
ERIC Educational Resources Information Center
High/Scope Educational Research Foundation, Ypsilanti, MI.
These conference proceedings provide summaries of 66 presentations on various aspects of the High/Scope educational approach. In addition to summaries of special presentations on music and movement, topics addressed include: (1) observation/feedback strategies; (2) adult-child interaction; (3) songs in daily routines; (4) High/Scope for infants…
Mammalian Polyamine Metabolism and Function
Pegg, Anthony E.
2009-01-01
Summary Polyamines are ubiquitous small basic molecules that play multiple essential roles in mammalian physiology. Their cellular content is highly regulated and there is convincing evidence that altered metabolism is involvement in many disease states. Drugs altering polyamine levels may therefore have a variety of important targets. This review will summarize the current state of understanding of polyamine metabolism and function, the regulation of polyamine content, and heritable pathological conditions that may be derived from altered polyamine metabolism. PMID:19603518
Design of a neural network simulator on a transputer array
NASA Technical Reports Server (NTRS)
Mcintire, Gary; Villarreal, James; Baffes, Paul; Rua, Monica
1987-01-01
A brief summary of neural networks is presented which concentrates on the design constraints imposed. Major design issues are discussed together with analysis methods and the chosen solutions. Although the system will be capable of running on most transputer architectures, it currently is being implemented on a 40-transputer system connected to a toroidal architecture. Predictions show a performance level equivalent to that of a highly optimized simulator running on the SX-2 supercomputer.
Interrelationships of Hormones, Diet, Body Size and Breast Cancer among Hispanic Women
2008-09-01
susceptible, gain excess weight due to physical inactivity, and consume a high-fat, low-fiber diet during adolescence and adulthood. It is clear...status, and use of oral contraceptives , as well as physical activity levels. In summary, the findings of our study that serum leptin concentrations were...history of breast cancer, age at menarche, menopausal status, age at menopause, parity, age at first live birth, BMI, use of oral contraceptives , use of
NASA Technical Reports Server (NTRS)
Rodriggs, Liana
2017-01-01
Since 2012, the Advanced EVA Development team has been maturing the design for an exploration suit (xEMU) capable of supporting Deep Space Gateway missions with the goal of demonstrating the core system architecture (xEMU Lite) on ISS by the mid-2020s. This presentation will provide a high-level status on progress made since the 2016 EVA Workshop, an overview of the xEMU architecture, and a summary of new development milestones and decision points between now and 2024.
Fuzzy logic controllers: A knowledge-based system perspective
NASA Technical Reports Server (NTRS)
Bonissone, Piero P.
1993-01-01
Over the last few years we have seen an increasing number of applications of Fuzzy Logic Controllers. These applications range from the development of auto-focus cameras, to the control of subway trains, cranes, automobile subsystems (automatic transmissions), domestic appliances, and various consumer electronic products. In summary, we consider a Fuzzy Logic Controller to be a high level language with its local semantics, interpreter, and compiler, which enables us to quickly synthesize non-linear controllers for dynamic systems.
ERIC Educational Resources Information Center
Brock, Stephen E., Ed.
2011-01-01
This column features summaries of five research articles relevant to school crisis response. The first, "High School Teachers' Experiences With Suicidal Students," summarized by Robyn Bratica, offers the results of a study examining high school teachers' experiences with suicidal students and suggests that contact with suicidal students is very…
High expression of nucleobindin 2 is associated with poor prognosis in gastric cancer.
Altan, Bolag; Kaira, Kyoichi; Okada, Shuichi; Saito, Tsugumichi; Yamada, Eijiro; Bao, Halin; Bao, Pinjie; Takahashi, Kengo; Yokobori, Takehiko; Tetsunari, Oyama; Nishiyama, Masahiko; Yamada, Masanobu
2017-07-01
Nucleobindin 2 has been reported that its high expression is associated with poor outcome and promotes cell migration and lymph node metastasis in breast cancer, colon cancer, and prostate cancer. However, we aimed to investigate the nucleobindin 2 expression in gastric cancer tissues and adjacent non-tumor tissues and its potential relevance to clinicopathological factors and prognosis using immunohistochemical analysis. In our study, nucleobindin 2 level in gastric cancer tissues was higher than in non-tumor tissues. A high expression of nucleobindin 2 is significantly associated with tumor depth, lymph node metastasis, lymphatic invasion, venous invasion, and clinical stage. Furthermore, the expression level of nucleobindin 2 protein was independent predictor of progression-free survival. In summary, nucleobindin 2 might play a crucial role in gastric cancer development and could serve as an independent predictor of prognosis of gastric cancer patients.
Sekikawa, Akira; Steingrimsdottir, Laufey; Ueshima, Hirotsugu; Shin, Chol; Curb, J. David; Evans, Rhobert W.; Hauksdottir, Alda M.; Kadota, Aya; Choo, Jina; Masaki, Kamal; Thorsson, Bolli; Launer, Lenore J.; Garcia, Melisa E.; Maegawa, Hiroshi; Willcox, Bradley J.; Eiriksdottir, Gudny; Fujiyoshi, Akira; Miura, Katsuyuki; Harris, Tamara B.; Kuller, Lewis H.; Gudnason, Vilmundur
2012-01-01
Summary In the 1990’s Iceland and Japan were known as countries with high fish consumption whereas coronary heart disease (CHD) mortality in Iceland was high and that in Japan was low among developed countries. We described recent data fish consumption and CHD mortality from publicly available data. We also measured CHD risk factors and serum levels of marine-derived n-3 and other fatty acids from population-based samples of 1,324 men in Iceland, Japan, South Korea, and the US. CHD mortality in men in Iceland was almost 3 times as high as that in Japan and South Korea. Generally a profile of CHD risk factors in Icelanders compared to Japanese was more favorable. Serum marine-derived n-3 fatty acids in Iceland were significantly lower than in Japan and South Korea but significantly higher than in the US. PMID:22658580
Software Assists in Responding to Anomalous Conditions
NASA Technical Reports Server (NTRS)
James, Mark; Kronbert, F.; Weiner, A.; Morgan, T.; Stroozas, B.; Girouard, F.; Hopkins, A.; Wong, L.; Kneubuhl, J.; Malina, R.
2004-01-01
Fault Induced Document Retrieval Officer (FIDO) is a computer program that reduces the need for a large and costly team of engineers and/or technicians to monitor the state of a spacecraft and associated ground systems and respond to anomalies. FIDO includes artificial-intelligence components that imitate the reasoning of human experts with reference to a knowledge base of rules that represent failure modes and to a database of engineering documentation. These components act together to give an unskilled operator instantaneous expert assistance and access to information that can enable resolution of most anomalies, without the need for highly paid experts. FIDO provides a system state summary (a configurable engineering summary) and documentation for diagnosis of a potentially failing component that might have caused a given error message or anomaly. FIDO also enables high-level browsing of documentation by use of an interface indexed to the particular error message. The collection of available documents includes information on operations and associated procedures, engineering problem reports, documentation of components, and engineering drawings. FIDO also affords a capability for combining information on the state of ground systems with detailed, hierarchically-organized, hypertext- enabled documentation.
A study on Nim expression in Bacteroides fragilis
Leitsch, David; Sóki, József; Kolarich, Daniel; Urbán, Edit; Nagy, Elisabeth
2016-01-01
Summary Members of the genus Bacteroides, mainly Bacteroides fragilis, can cause severe disease in man, especially after intestinal perforation in the course of abdominal surgery. Treatment is based on a small number of antibiotics, including metronidazole which has proved to be highly reliable throughout the last 40 to 50 years. Nevertheless, metronidazole resistance does occur in Bacteroides and has been mainly attributed to Nim proteins, a class of proteins with suggested nitroreductase function. Despite the potentially high importance of Nim proteins for human health, information on the expression of nim genes in Bacteroides fragilis is still lacking. It was the aim of this study to demonstrate expression of nim genes in B. fragilis at the protein level and, further, to correlate the level of Nim levels with the level of metronidazole resistance. By application of two-dimensional gel electrophoresis, Nim proteins could be readily identified in nim-positive strains but their levels were not elevated to a relevant extent after induction of resistance to high doses of metronidazole. Thus, the presented data do not provide evidence for Nim proteins acting as nitroreductases using metronidazole as a substrate because no correlation of Nim levels and level of resistance could be observed. Further, no evidence was found that Nim proteins protect B. fragilis from metronidazole by sequestering activated metronidazole. PMID:24448511
Locke, Glenn L.
2001-01-01
The U.S. Geological Survey, in support of the U.S. Department of Energy, Yucca Mountain Site Characterization Project, collects, compiles, and summarizes hydrologic data in the Yucca Mountain region. The data are collected to allow assessments of ground-water resources during studies to determine the potential suitability of Yucca Mountain for storing high-level nuclear waste. Data on ground-water levels at 34 wells and a fissure (Devils Hole), ground-water discharge at 5 springs and a flowing well, and total reported ground-water withdrawals within Crater Flat, Jackass Flats, Mercury Valley, and the Amargosa Desert are presented for calendar year 1998. Data collected prior to 1998 are graphically presented and data collected by other agencies (or as part of other Geolgical Survey programs) are included to further indicate variations of ground-water levels, discharges, and withdrawals through time. A statistical summary of ground-water levels at seven wells in Jackass Flats is presented to indicate potential effects of ground-water withdrawals associated with U.S. Department of Energy activities near Yucca Mountain. The statistical summary includes the number of measurements, the maximum, minimum, and median water-level altitudes, and the average deviation of measured water-level altitudes for selected baseline periods and for calendar years 1992-98. At two water-supply wells and a nearby observation well, median water levels for calendar year 1998 were slightly lower (0.2 to 0.3 foot) than for their respective baseline periods. At the remaining four wells in Jackass Flats, median water levels for 1998 were unchanged at two wells and slightly higher (0.4 and 1.4 foot) at two wells than those for their respective baseline periods.
Heavy metals pollution levels and children health risk assessment of Yerevan kindergartens soils.
Tepanosyan, Gevorg; Maghakyan, Nairuhi; Sahakyan, Lilit; Saghatelyan, Armen
2017-08-01
Children, the most vulnerable urban population group, are exceptionally sensitive to polluted environments, particularly urban soils, which can lead to adverse health effects upon exposure. In this study, the total concentrations of Ag, As, Ba, Cd, Co, Cr, Cu, Fe, Hg, Mn, Mo, Ni, Pb, Ti, V, and Zn were determined in 111 topsoil samples collected from kindergartens in Yerevan. The objectives of this study were to evaluate heavy metal pollution levels of kindergarten's soils in Yerevan, compare with national legal and international requirements on heavy metal contents in kindergarten soil, and assess related child health risk. Multivariate geostatistical analyses suggested that the concentrations of Ag, As, Ba, Cd, Cu, Hg, Mo, Pb, and Zn observed in the kindergarten's topsoil may have originated from anthropogenic sources, while Co, Cr, Fe, Mn, Ni, Ti, and V mostly come from natural sources. According to the Summary pollution index (Zc), 102 kindergartens belong to the low pollution level, 7 to the moderate and only 2 to the high level of pollution. Summary concentration index (SCI) showed that 109 kindergartens were in the allowable level, while 2 featured in the low level of pollution. The health risk assessment showed that in all kindergartens except for seven, non-carcinogenic risk for children was detected (HI>1), while carcinogenic risk from arsenic belongs to the very low (allowable) level. Cr and multi-element carcinogenic risk (RI) exceeded the safety level (1.0E- 06) in all kindergartens and showed that the potential of developing cancer, albeit small, does exist. Therefore, city's kindergartens require necessary remedial actions to eliminate or reduce soil pollution and heavy metal-induced health risks. Copyright © 2017 Elsevier Inc. All rights reserved.
Patel, Amit; Bakina, Daria; Kirk, Jim; von Lutcken, Scott; Donnelly, Tom; Stone, William; Ashley-Collins, Heather; Tibbals, Karen; Ricker, Lynn; Adler, Jeffrey; Ewing, John; Blechman, Michelle; Fox, Sherry; Leopold, Will; Ryan, Daniel; Wray, Donna; Turkoz, Heather
2018-05-16
Counseling patients with written materials relies equally on patients' health literacy to understand their disease and its treatment, and the written materials' effectiveness communicating clearly in accessible and actionable ways. Only about 12% of the US population is adequately health literate. To explore the impact of reducing the health literacy demands of written patient health information. 805 patients were screened for health literacy, and recruited for balanced cohorts of adequate and low literacy, and high and normal blood pressure. Half of each patient cohort received either standard or "health literacy-friendly" drug summaries (i.e. Patient Package Inserts, or PPIs or "leaflets") along with a standardized health literacy assessment scale. The literacy-friendly drug summary improved comprehension of drug-related information overall from 50% to 71% correct responses. Adequate literacy patients improved from 58% correct to 90%, while lower literacy patients improved from 42% to 52% correct in response to the health literacy-friendly PPIs. Health literacy demands require special attention in developing and using written drug summary materials. Additionally, pharmacists should be provided additional information and counseling support materials to facilitate communications with low health literacy level patients. Copyright © 2018 Elsevier Inc. All rights reserved.
ERIC Educational Resources Information Center
Williams, Immanuel James; Williams, Kelley Kim
2016-01-01
Understanding summary statistics and graphical techniques are building blocks to comprehending concepts beyond basic statistics. It's known that motivated students perform better in school. Using examples that students find engaging allows them to understand the concepts at a deeper level.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bryant, Shea; Develin, Thomas; Flores, Victor
The U.S. Department of Energy (DOE) conducts environmental monitoring at the Portsmouth Gaseous Diffusion Plant Site (PORTS) on an ongoing basis. Each year, the information collected is presented in a data volume and a comprehensive publication entitled the Annual Site Environmental Report (ASER). This year, a class at Waverly High School (WHS), located in Pike County, Ohio, developed this summary report. Both the ASER and this summary report are important as they allow DOE to clearly and concisely explain our environmental monitoring programs to our many stakeholders. The information presented in this summary shows that the PORTS site near Piketon,more » Ohio, is safe due in part to the Department’s focus on safety. The work at DOE facilities is highly detailed and technically complex, but DOE is committed to performing each of these activities safely. DOE’s first priority is to protect the well-being of our workers, the surrounding communities, and the environment. DOE would like to offer its sincerest appreciation to the students and faculty leader at Waverly High School who worked on this summary document. DOE congratulates each of you for your effort, enthusiasm, and willingness to support this project. DOE hopes you enjoy reading the PORTS 2013 Annual Site Environmental Report Summary.« less
2005-06 NCAA[R] Gender-Equity Report
ERIC Educational Resources Information Center
DeHass, Denise
2008-01-01
This report provides summary information concerning personnel, revenues, expenses and other comparative variables of men's and women's intercollegiate athletics programs at NCAA member institutions for the 2005-2006 fiscal year. The summary information may be used to help track gender-equity issues at the collegiate level. This report is the…
Summary of Development as a Reflective Practitioner
ERIC Educational Resources Information Center
Quan, Hong; Yang, Shihua; Chen, Honglin
2010-01-01
This paper is a summary which explores the effectiveness and evaluation of my development as a reflective practitioner. It focuses on development with two useful theories about learning and teaching. They are about deep learning & surface learning and levels of teaching. Actually, when I put these theories to practice reflectively, the result…
Windsor, Timothy D; Rodgers, Bryan; Butterworth, Peter; Anstey, Kaarin J; Jorm, Anthony F
2006-09-01
The effects of using different approaches to scoring the SF-12 summary scales of physical and mental health were examined with a view to informing the design and interpretation of community-based survey research. Data from a population-based study of 7485 participants in three cohorts aged 20-24, 40-44 and 60-64 years were used to examine relationships among measures of physical and mental health calculated from the same items using the SF-12 and RAND-12 approaches to scoring, and other measures of chronic physical conditions and psychological distress. A measure of physical health constructed using the RAND-12 scoring showed a monotonic negative association with psychological distress as measured by the Goldberg depression and anxiety scales. However, a non-monotonic association was evident in the relationship between SF-12 physical health scores and distress, with very high SF-12 physical health scores corresponding with high levels of distress. These relationships highlight difficulties in interpretation that can arise when using the SF-12 summary scales in some analytical contexts. It is recommended that community surveys that measure physical and mental functioning using the SF-12 items generate summary scores using the RAND-12 protocol in addition to the SF-12 approach. In general, researchers should be wary of using factor scores based on orthogonal rotation, which assumes that measures are uncorrelated, to represent constructs that have an actual association.
Weir, Christopher J; Butcher, Isabella; Assi, Valentina; Lewis, Stephanie C; Murray, Gordon D; Langhorne, Peter; Brady, Marian C
2018-03-07
Rigorous, informative meta-analyses rely on availability of appropriate summary statistics or individual participant data. For continuous outcomes, especially those with naturally skewed distributions, summary information on the mean or variability often goes unreported. While full reporting of original trial data is the ideal, we sought to identify methods for handling unreported mean or variability summary statistics in meta-analysis. We undertook two systematic literature reviews to identify methodological approaches used to deal with missing mean or variability summary statistics. Five electronic databases were searched, in addition to the Cochrane Colloquium abstract books and the Cochrane Statistics Methods Group mailing list archive. We also conducted cited reference searching and emailed topic experts to identify recent methodological developments. Details recorded included the description of the method, the information required to implement the method, any underlying assumptions and whether the method could be readily applied in standard statistical software. We provided a summary description of the methods identified, illustrating selected methods in example meta-analysis scenarios. For missing standard deviations (SDs), following screening of 503 articles, fifteen methods were identified in addition to those reported in a previous review. These included Bayesian hierarchical modelling at the meta-analysis level; summary statistic level imputation based on observed SD values from other trials in the meta-analysis; a practical approximation based on the range; and algebraic estimation of the SD based on other summary statistics. Following screening of 1124 articles for methods estimating the mean, one approximate Bayesian computation approach and three papers based on alternative summary statistics were identified. Illustrative meta-analyses showed that when replacing a missing SD the approximation using the range minimised loss of precision and generally performed better than omitting trials. When estimating missing means, a formula using the median, lower quartile and upper quartile performed best in preserving the precision of the meta-analysis findings, although in some scenarios, omitting trials gave superior results. Methods based on summary statistics (minimum, maximum, lower quartile, upper quartile, median) reported in the literature facilitate more comprehensive inclusion of randomised controlled trials with missing mean or variability summary statistics within meta-analyses.
Considerations on automation of coating machines
NASA Astrophysics Data System (ADS)
Tilsch, Markus K.; O'Donnell, Michael S.
2015-04-01
Most deposition chambers sold into the optical coating market today are outfitted with an automated control system. We surveyed several of the larger equipment providers, and nine of them responded with information about their hardware architecture, data logging, level of automation, error handling, user interface, and interfacing options. In this paper, we present a summary of the results of the survey and describe commonalities and differences together with some considerations of tradeoffs, such as between capability for high customization and simplicity of operation.
JOVIAL J73 Automated Verification System - Study Phase
1980-08-01
capabil- ities for the tool, and the high-level design of the tool are also described. Future capabilities for the tool are identified. -N CONTENTS...Implemented Test Tools 3-22 4 FUNCTIONAL DESCRIPTION OF Ji3AVS 4-1 4.1 Summary of Capabilities 4-3 4.2 J 3.AVS Operat . 4-11 5 DESIGN OF J73AVS 5-1 6...Both JOVIAL languages are primarily designed for command and control system programming. They are es- pecially well suited to large systems requiring
Biological and related chemical research concerning subseabed disposal of high level nuclear waste
NASA Astrophysics Data System (ADS)
Mullin, M. M.; Gomez, L. S.
1981-10-01
This report contains: recommendations (research on radionuclide movement processes, research on radionuclide transport processes, administration and policy); abstracts of plenary talks (Large-Scale Distributions of Deep-Sea Benthic Organisms, Transfer Processes Between Water Column and Benthos, Particle Reworking and Biogeochemistry of Sediments, and radioecological Aspects of Deep-Sea Waste Disposal of Radionuclides. Summaries of subgroup discussions (geochemistry and microbiology, benthic biology, pelagic biology, radioecology); and appendices (model of physical biological transfers, and participants and institutional affiliations) are also presented.
Rocca-Serra, Philippe; Brandizi, Marco; Maguire, Eamonn; Sklyar, Nataliya; Taylor, Chris; Begley, Kimberly; Field, Dawn; Harris, Stephen; Hide, Winston; Hofmann, Oliver; Neumann, Steffen; Sterk, Peter; Tong, Weida; Sansone, Susanna-Assunta
2010-01-01
Summary: The first open source software suite for experimentalists and curators that (i) assists in the annotation and local management of experimental metadata from high-throughput studies employing one or a combination of omics and other technologies; (ii) empowers users to uptake community-defined checklists and ontologies; and (iii) facilitates submission to international public repositories. Availability and Implementation: Software, documentation, case studies and implementations at http://www.isa-tools.org Contact: isatools@googlegroups.com PMID:20679334
Structure based design of 11β-HSD1 inhibitors.
Singh, Suresh; Tice, Colin
2010-11-01
Controlling elevated tissue-specific levels of cortisol may provide a novel therapeutic approach for treating metabolic syndrome. This concept has spurred large scale medicinal chemistry efforts in the pharmaceutical industry for the design of 11β-HSD1 inhibitors. High resolution X-ray crystal structures of inhibitors in complex with the enzyme have facilitated the structure-based design of diverse classes of molecules. A summary of binding modes, trends in structure-activity relationships, and the pharmacodynamic data of inhibitors from each class is presented.
Salva I Tomas, P A
1991-01-01
The impact of tourism on population trends in Spain's Balearic Islands since 1950 is analyzed. The author notes that tourism generated high levels of in-migration and an increase in fertility until about 1975. Subsequently, the birth rate has declined, population growth has slowed down, and the population has grown older. There is still a noticeable contrast between the demography of coastal areas and inland agrarian regions. (SUMMARY IN ENG AND SPA)
NASA Technical Reports Server (NTRS)
1981-01-01
Space systems concepts were identified and defined and evaluated as to their performance, risks, and technical viability in order to select the most attractive approach for disposal of high level nuclear wastes in space. Major study areas discussed include: (1) mission and operations analysis; (2) waste payload systems; (3) flight support system; (4) launch site systems; (5) launch vehicle systems; (6) orbit transfer system; (7) space disposal destinations; and (8) systems integration and evaluation.
2008-10-01
Equipment Department of the Dutch Ministry of Defence tasked TNO Defence, Security and Safety to perform AP mine shoe tests to study the protection level...would not provide more insight. Therefore only two tests at 75 g were performed . The test results are summarized in Table 2. The high speed video...be able to better place foot into shoe . But still damage of gelatine prior to test. Pretest x-ray performed to show damage prior to test. The
Unintended pregnancy and unsafe abortion in the Philippines: context and consequences.
Hussain, Rubina; Finer, Lawrence B
2013-04-01
Despite advances in reproductive health law, many Filipino women experience unintended pregnancies, and because abortion is highly stigmatized in the country, many who seek abortion undergo unsafe procedures. This report provides a summary of reproductive health indicators in the Philippines—in particular, levels of contraceptive use, unplanned pregnancy and unsafe abortion—and describes the sociopolitical context in which services are provided, the consequences of unintended pregnancy and unsafe abortion,and recommendations for improving access to reproductive health services.
International High/Scope Registry Conference Proceedings (Ypsilanti, Michigan, May 5-8, 1998).
ERIC Educational Resources Information Center
High/Scope Educational Research Foundation, Ypsilanti, MI.
These conference proceedings provide summaries of 71 presentations on various aspects of the High/Scope educational approach. In addition to summaries of special presentations on music and movement, topics addressed include: (1) student engagement; (2) outdoor learning; (3) change strategies; (4) various discussions of the Child Observation…
Del Rosario, Adeline; McDermott, Mindy M.; Panee, Jun
2015-01-01
High fat diet is a major causative factor of overweight and obesity, which are associated with increased risk of neuropsychiatric diseases, such as anxiety and depression. In this study, we investigated the protective effects of bamboo extract (BEX) on anxiety- and depression-like neurobehaviors in mice treated with a high fat diet. Male mice with CD-1 genetic background were treated for 2 months with either a standard or a high fat diet (10% or 45% calories from fat, respectively), with or without BEX supplement (11 g dry mass per 17 MJ). The anxiety levels of the mice were evaluated using open field and hole-board tests, and depression was measured using force swimming test. The anxiety responses of the animals were found significantly increased after high fat diet treatment, and this elevation was effectively abolished by BEX supplement. High fat diet seemed to have an anti-depressive effect in the mice at the tested time point, but the effect of BEX supplement on the depression level of the animals was not conclusive. High fat diet significantly decreased total glutathione content in the blood while BEX supplement increased glutathione oxidation. In summary, this study showed that decreased total glutathione concentration in the blood co-occurred with high fat treatment, high anxiety level and low depression level in the mice; and when supplemented in a high fat diet, BEX had anxiolytic effect in the mice. PMID:22313665
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1978-10-03
This report is a six-part statistical summary of surface weather observations for Torrejon AB, Madrid Spain. It contains the following parts: (A) Weather Conditions; Atmospheric Phenomena; (B) Precipitation, Snowfall and Snow Depth (daily amounts and extreme values); (C) Surface winds; (D) Ceiling Versus Visibility; Sky Cover; (E) Psychrometric Summaries (daily maximum and minimum temperatures, extreme maximum and minimum temperatures, psychrometric summary of wet-bulb temperature depression versus dry-bulb temperature, means and standard deviations of dry-bulb, wet-bulb and dew-point temperatures and relative humidity); and (F) Pressure Summary (means, standard, deviations, and observation counts of station pressure and sea-level pressure). Data in thismore » report are presented in tabular form, in most cases in percentage frequency of occurrence or cumulative percentage frequency of occurrence tables.« less
Quantitative and qualitative analysis of student textbook summary writing
NASA Astrophysics Data System (ADS)
Demaree, Dedra; Allie, Saalih; Low, Michael; Taylor, Julian
2008-10-01
The majority of "special access" students at the University of Cape Town are second language English speakers for whom reading the physics textbook is daunting. As a strategy to encourage meaningful engagement with the text, students wrote textbook summaries due the day material was covered in class. The summaries were returned, and they could bring them or re-write them for use during their examinations. A framework was developed to analyze the summaries based on Waywood, defining three cognitive levels seen in mathematics journaling: recounting, summarizing, and dialoging. This framework was refined, expanded, and tested. Interviews with students were conducted for their views on summary writing and survey questions were included on their final exams. The study was carried out in the 2007 spring semester of the "Foundation Physics Course," a component of the special access program.
Noise Levels and Data Correction Analysis for Seven General Aviation Propeller Aircraft.
1980-09-01
31-1 60 M, NORTH THRESHOLD RNWY. 13 DATE: JUNE 19,1978 EVENT EPNL DBA(M) DBD (M) OASPL PNL(M) PNLT(M) DUR(P) TC AEPNL * I APPROACH 2 87.2 78.7 85.6...DOT/TSC 10/18/78 SUMMARY NOISE LEVEL. DATA AS MEASURED * SITE NO. 31-2 2000 M. NORTH THRESHOLD RNWY. 13 DATE: JUNE 19,1978 EVENT EPNL DBA(M) DBD (M...DOT/TSC 11/13/78 SUMMARY NOISE LEVEL DATA AS MEASURED SITE NO, 31-3 3485 M, NORTH THRESHOLD RNWY. 13 DATE: JUNE 19P1978 EVENT EPNL DBA(M) DBD (M) OASPL
McCary, Christine A.; Abdala-Valencia, Hiam; Berdnikovs, Sergejs; Cook-Mills, Joan M.
2011-01-01
We have reported that supplemental doses of the α- and γ-tocopherol isoforms of vitamin E decrease and increase, respectively, allergic lung inflammation. We have now assessed whether these effects of tocopherols are reversible. For these studies, mice were treated with antigen and supplemental tocopherols in a first phase of treatment followed by a 4 week clearance phase and then the mice received a second phase of antigen and tocopherol treatments. The pro-inflammatory effects of supplemental levels of γ-tocopherol in phase 1 were only partially reversed by supplemental α-tocopherol in phase 2 but were completely reversed by raising α-tocopherol levels 10-fold in phase 2. When γ-tocopherol levels were increased 10-fold (highly-elevated tocopherol) so that the lung tissue γ-tocopherol levels were equal to the lung tissue levels of supplemental α-tocopherol, γ-tocopherol reduced leukocyte numbers in the lung lavage fluid. In contrast to the lung lavage fluid, highly-elevated levels of γ-tocopherol increased inflammation in the lung tissue. These regulatory effects of highly-elevated tocopherols on tissue inflammation and lung lavage fluid were reversible in a second phase of antigen challenge without tocopherols. In summary, the pro-inflammatory effects of supplemental γ-tocopherol on lung inflammation were partially reversed by supplemental levels of α-tocopherol but were completely reversed by highly-elevated-levels of α-tocopherol. Also, highly-elevated levels of γ-tocopherol were inhibitory and reversible in lung lavage but, importantly, were pro-inflammatory in lung tissue sections. These results have implications for future studies with tocopherols and provide a new context in which to review vitamin E studies in the literature. PMID:21317387
Reliability Demonstration Approach for Advanced Stirling Radioisotope Generator
NASA Technical Reports Server (NTRS)
Ha, CHuong; Zampino, Edward; Penswick, Barry; Spronz, Michael
2010-01-01
Developed for future space missions as a high-efficiency power system, the Advanced Stirling Radioisotope Generator (ASRG) has a design life requirement of 14 yr in space following a potential storage of 3 yr after fueling. In general, the demonstration of long-life dynamic systems remains difficult in part due to the perception that the wearout of moving parts cannot be minimized, and associated failures are unpredictable. This paper shows a combination of systematic analytical methods, extensive experience gained from technology development, and well-planned tests can be used to ensure a high level reliability of ASRG. With this approach, all potential risks from each life phase of the system are evaluated and the mitigation adequately addressed. This paper also provides a summary of important test results obtained to date for ASRG and the planned effort for system-level extended operation.
Efficient Transplantation via Antibody-based Clearance of Hematopoietic Stem Cell Niches
Czechowicz, Agnieszka; Kraft, Daniel; Weissman, Irving L.; Bhattacharya, Deepta
2008-01-01
Summary We demonstrate that administration of a depleting antibody specific for c-kit leads to the highly efficient removal of host hematopoietic stem cells (HSCs) and high levels of donor HSC chimerism following transplantation. Upon intravenous transplantation, hematopoietic stem cells (HSCs) can home to specialized niches, yet most HSCs fail to engraft unless recipients are subjected to toxic preconditioning. Here, we provide evidence that, aside from immune barriers, donor HSC engraftment is restricted by occupancy of appropriate niches by host HSCs. Administration of ACK2, an antibody that blocks c-kit function, led to the transient removal of >98% of endogenous HSCs in immunodeficient mice. Subsequent transplantation of these animals with donor HSCs led to chimerism levels of up to 90%. Extrapolation of these methods to humans may enable mild but effective conditioning regimens for transplantation. PMID:18033883
Serum Bicarbonate and Mortality in Stage 3 and Stage 4 Chronic Kidney Disease
Schold, Jesse D.; Arrigain, Susana; Jolly, Stacey E.; Wehbe, Edgard; Raina, Rupesh; Simon, James F.; Srinivas, Titte R.; Jain, Anil; Schreiber, Martin J.; Nally, Joseph V.
2011-01-01
Summary Background and objectives The incidence and prevalence of metabolic acidosis increase with declining kidney function. We studied the associations of both low and high serum bicarbonate levels with all-cause mortality among stage 3 and 4 chronic kidney disease (CKD) patients. Design, setting, participants, & measurements We examined factors associated with low (<23 mmol/L) and high (>32 mmol/L) serum bicarbonate levels using logistic regression models and associations between bicarbonate and all-cause mortality using Cox-proportional hazard models, Kaplan–Meier survival curves, and time-dependent analysis. Results Out of 41,749 patients, 13.9% (n = 5796) had low and 1.6% (n = 652) had high serum bicarbonate levels. After adjusting for relevant covariates, there was a significant association between low serum bicarbonate and all-cause mortality (hazard ratio [HR] 1.23, 95% CI 1.16, 1.31). This association was not statistically significant among patients with stage 4 CKD and diabetes. The time-dependent analysis demonstrated a significant mortality risk associated with a decline from normal to low bicarbonate level (HR 1.59, 95% CI 1.49, 1.69). High serum bicarbonate levels were associated with death irrespective of the level of kidney function (HR 1.74, 95% CI 1.52, 2.00). When serum bicarbonate was examined as a continuous variable, a J-shaped relationship was noted between serum bicarbonate and mortality. Conclusions Low serum bicarbonate levels are associated with increased mortality among stage 3 CKD patients and patients without diabetes. High serum bicarbonate levels are associated with mortality in both stage 3 and stage 4 CKD patients. PMID:21885787
Scribner, Kim T.; Garner, G.W.; Amstrup, Steven C.; Cronin, M.A.; Dizon, Andrew E.; Chivers, Susan J.; Perrin, William F.
1997-01-01
A summary of existing population genetics literature is presented for polar bears (Ursus maritimus) and interpreted in the context of the species' life-history characteristics and regional heterogeneity in environmental regimes and movement patterns. Several nongenetic data sets including morphology, contaminant levels, geographic variation in reproductive characteristics, and the location and distribution of open-water foraging habitat suggest some degree of spatial structuring. Eleven populations are recognized by the IUCN Polar Bear Specialist Group. Few genetics studies exist for polar bears. Interpretation and generalizations of regional variation in intra- and interpopulation levels of genetic variability are confounded by the paucity of data from many regions and by the fact that no single informative genetic marker has been employed in multiple regions. Early allozyme studies revealed comparatively low levels of genetic variability and no compelling evidence of spatial structuring. Studies employing mitochondrial DNA (mtDNA) also found low levels of genetic variation, a lack of phylogenetic structure, and no significant evidence for spatial variation in haplotype frequency. In contrast, microsatellite variable number of tandem repeat (VNTR) loci have revealed significant heterogeneity in allele frequency among populations in the Canadian Arctic. These regions are characterized by archipelgic patterns of sea-ice movements. Further studies using highly polymorphic loci are needed in regions characterized by greater polar bear dependency on pelagic sea-ice movements and in regions for which no data currently exist (i.e., Laptev and Novaya Zemlya/Franz Josef).
Toh, Sengwee; Gagne, Joshua J; Rassen, Jeremy A; Fireman, Bruce H; Kulldorff, Martin; Brown, Jeffrey S
2013-08-01
A distributed research network (DRN) of electronic health care databases, in which data reside behind the firewall of each data partner, can support a wide range of comparative effectiveness research (CER) activities. An essential component of a fully functional DRN is the capability to perform robust statistical analyses to produce valid, actionable evidence without compromising patient privacy, data security, or proprietary interests. We describe the strengths and limitations of different confounding adjustment approaches that can be considered in observational CER studies conducted within DRNs, and the theoretical and practical issues to consider when selecting among them in various study settings. Several methods can be used to adjust for multiple confounders simultaneously, either as individual covariates or as confounder summary scores (eg, propensity scores and disease risk scores), including: (1) centralized analysis of patient-level data, (2) case-centered logistic regression of risk set data, (3) stratified or matched analysis of aggregated data, (4) distributed regression analysis, and (5) meta-analysis of site-specific effect estimates. These methods require different granularities of information be shared across sites and afford investigators different levels of analytic flexibility. DRNs are growing in use and sharing of highly detailed patient-level information is not always feasible in DRNs. Methods that incorporate confounder summary scores allow investigators to adjust for a large number of confounding factors without the need to transfer potentially identifiable information in DRNs. They have the potential to let investigators perform many analyses traditionally conducted through a centralized dataset with detailed patient-level information.
NASA Technical Reports Server (NTRS)
1978-01-01
Sea level, static, ground testing of the over-the-wing engine and boilerplate nacelle components was performed. The equipment tested and the test facility are described. Summaries of the instrumentations, the chronological history of the tests, and the test results are presented.
Students Training for Academic Readiness (STAR): Year Three Evaluation Report. Executive Summary
ERIC Educational Resources Information Center
Texas Center for Educational Research, 2010
2010-01-01
This executive summary presents findings from the Year 3 evaluation of Texas' state-level Gaining Early Awareness and Readiness for Undergraduate Programs, or GEAR UP, grant. GEAR UP grant requirements include an evaluation component designed to assess program effectiveness and to measure progress toward project goals. To this end, the evaluation…
ERIC Educational Resources Information Center
Kauh, Tina J.
2011-01-01
This executive summary highlights the main findings from our participation and outcomes analysis of the "AfterZone" initiative--a citywide system-building effort in Providence, Rhode Island, that aims to provide high-quality, accessible out-of-school-time services to middle school youth. The summary briefly defines the AfterZone's unique…
Veterinary Research Manpower Development for Defense
2007-09-01
Participatory Disease Surveillance Method for Detection of Highly Pathogenic Avian Influenza in Java, Indonesia Rebecca Steers Dr. Lindenmeyer Detection of...Transmission of Nipah Virus in Bangladesh Summary: My project aims to investigate the risk of zoonotic transmission of Nipah virus as a food-borne...Participatory Disease Surveillance Method for Detection of Highly Pathogenic Avian Influenza in Java, Indonesia Summary: Two epidemics of H5N1 Highly
Advanced Initiation Systems Manufacturing Level 2 Milestone Completion Summary
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chow, R; Schmidt, M
2009-10-01
Milestone Description - Advanced Initiation Systems Detonator Design and Prototype. Milestone Grading Criteria - Design new generation chip slapper detonator and manufacture a prototype using advanced manufacturing processes, such as all-dry chip metallization and solvent-less flyer coatings. The advanced processes have been developed for manufacturing detonators with high material compatibility and reliability to support future LEPs, e.g. the B61, and new weapons systems. Perform velocimetry measurements to determine slapper velocity as a function of flight distance. A prototype detonator assembly and stripline was designed for low-energy chip slappers. Pictures of the prototype detonator and stripline are shown. All-dry manufacturing processesmore » were used to address compatibility issues. KCP metallized the chips in a physical vapor deposition system through precision-aligned shadow masks. LLNL deposited a solvent-less polyimide flyer with a processes called SLIP, which stands for solvent-less vapor deposition followed by in-situ polymerization. LANL manufactured the high-surface-area (HSA) high explosive (HE) pellets. Test fires of two chip slapper designs, radius and bowtie, were performed at LLNL in the High Explosives Application Facility (HEAF). Test fires with HE were conducted to establish the threshold firing voltages. pictures of the chip slappers before and after test fires are shown. Velocimetry tests were then performed to obtain slapper velocities at or above the threshold firing voltages. Figure 5 shows the slapper velocity as a function of distance and time at the threshold voltage, for both radius and bowtie bridge designs. Both designs were successful at initiating the HE at low energy levels. Summary of Accomplishments are: (1) All-dry process for chip manufacture developed; (2) Solventless process for slapper materials developed; (3) High-surface area explosive pellets developed; (4) High performance chip slappers developed; (5) Low-energy chip slapper detonator designs; and (6) Low-voltage threshold chip slapper detonator demonstrated.« less
Summary Report: NMSBA CY 2016 - AEgis Technologies Group Inc. #12458.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bellum, John Curtis; Field, Ella Suzanne
2016-12-01
AEgis requires large area partial mirror optics consisting of partially reflecting optical coatings on large dimension substrates for high energy laser (HEL) applications. The partial mirrors should transmit nearly the same small fraction of HEL radiation incident from a wide range of angles of incidence (AOIs), and the laser-induced damage threshold (LIDT) of the coatings should be high enough for them to be able to withstand direct exposure to near infrared CW HEL radiation at multi-kilowatt/cm2 power levels. The transmitted fraction of incident HEL radiation should reach an array of detectors at power levels high enough for reliable detection butmore » low enough to not damage the detectors. The reflected fraction of incident HEL radiation should scatter into a divergent pattern so as to be eye safe at a distance of ~ 200 m from the mirror in the case of 100 kilowatt incident laser power. The detector array together with the partial mirror optic and possible additional optics that provide divergent scattering of reflected HEL radiation constitute what AEgis refers to as a target board. The target board use environment may vary from benign, indoor laboratory conditions to harsh, outdoor conditions in tests on the ground as well as in air. Under this NMSBA project, Sandia agreed to apply its extensive expertise and capability in the design and production of high LIDT coatings on large dimension optics for high power pulsed laser radiation to advise and assist AEgis in the design and development of high LIDT coatings for the partial mirror optic. Sandia and AEgis met several times to discuss the partial mirror and target board requirements, and Sandia was guided in its work by these discussions as well as by the partial mirror and target board requirement summaries of Tables 1 and 2, respectively, that were provided by AEgis.« less
Materials experiment carrier concepts definition study. Volume 1: Executive summary, part 2
NASA Technical Reports Server (NTRS)
1981-01-01
The materials experiment carrier (MEC) is an optimized carrier for near term and advanced materials processing in space (MPS) research and commercial payloads. When coupled with the space platform (SP), the MEC can provide the extended duration, high power and low acceleration environment the MPS payload typically requires. The lowest cost, technically reasonable first step MEC that meets the MPS program missions objectives with minimum programmatic risks is defined. The effectiveness of the initial MEC/space platform idea for accommodating high priority, multidiscipline, R&D and commercial MPS payloads, and conducting MPS payload oprations at affordable funding and acceptable productivity levels is demonstrated.
Age and natural metabolically-intensive behavior affect oxidative stress and antioxidant mechanisms.
Williams, Jason B; Roberts, Stephen P; Elekonich, Michelle M
2008-06-01
Flying honey bees have among the highest mass-specific metabolic rates ever measured, suggesting that their flight muscles may experience high levels of oxidative stress during normal daily activities. We measured parameters of oxidative stress and antioxidant capacity in highly metabolic flight muscle and less active head tissue in cohorts of age-matched nurse bees, which rarely fly, and foragers, which fly several hours per a day. Naturally occurring foraging flight elicited an increase in flight muscle Hsp70 content in both young and old foragers; however catalase and total antioxidant capacity increased only in young flight muscle. Surprisingly, young nurse bees also showed a modest daily increase in Hsp70, catalase levels and antioxidant capacity, and these effects were likely due to collecting the young nurses soon after orientation flights. There were no differences in flight muscle carbonyl content over the course of daily activity and few differences in Hsp70, catalase, total antioxidant capacity and protein carbonyl levels in head tissue regardless of age or activity. In summary, honey bee flight likely produces high levels of reactive oxygen species in flight muscle that, when coupled with age-related decreases in antioxidant activity may be responsible for behavioral senescence and reduced longevity.
Indian Americans in Duluth. A Summary and Analysis of Recent Research.
ERIC Educational Resources Information Center
Harkins, Arthur M., Comp.; Woods, Richard G., Comp.
A summary of research relating to the Duluth, Minnesota, Indians is presented utilizing 12 major sections: an introduction; profiles of the "typical" Duluth (1) Indian resident, (2) male Indian resident, (3) female Indian resident, (4) Indian high school graduate, and (5) Indian high school nongraduate; the importance of education;…
Violence Prevention at Thurgood Marshall Academy Public Charter High School. Summary Brief
ERIC Educational Resources Information Center
Fontaine, Jocelyn; Debus-Sherrill, Sara; Downey, P. Mitchell; Lowry, Samantha S.
2010-01-01
This summary brief is based on research conducted by the Urban Institute's Justice Policy Center on the violence prevention activities taking place at the Thurgood Marshall Academy Public Charter High School during the 2008-2009 school year. Researchers from the Justice Policy Center conducted an assessment of the school's violence prevention…
International Space Station Increment-4/5 Microgravity Environment Summary Report
NASA Technical Reports Server (NTRS)
Jules, Kenol; Hrovat, Kenneth; Kelly, Eric; McPherson, Kevin; Reckart, Timothy
2003-01-01
This summary report presents the results of some of the processed acceleration data measured aboard the International Space Station during the period of December 2001 to December 2002. Unlike the past two ISS Increment reports, which were increment specific, this summary report covers two increments: Increments 4 and 5, hereafter referred to as Increment-4/5. Two accelerometer systems were used to measure the acceleration levels for the activities that took place during Increment-4/5. Due to time constraint and lack of precise timeline information regarding some payload operations and station activities, not a11 of the activities were analyzed for this report. The National Aeronautics and Space Administration sponsors the Microgravity Acceleration Measurement System and the Space Acceleration Microgravity System to support microgravity science experiments which require microgravity acceleration measurements. On April 19, 2001, both the Microgravity Acceleration Measurement System and the Space Acceleration Measurement System units were launched on STS-100 from the Kennedy Space Center for installation on the International Space Station. The Microgravity Acceleration Measurement System supports science experiments requiring quasi-steady acceleration measurements, while the Space Acceleration Measurement System unit supports experiments requiring vibratory acceleration measurement. The International Space Station Increment-4/5 reduced gravity environment analysis presented in this report uses acceleration data collected by both sets of accelerometer systems: The Microgravity Acceleration Measurement System, which consists of two sensors: the low-frequency Orbital Acceleration Research Experiment Sensor Subsystem and the higher frequency High Resolution Accelerometer Package. The low frequency sensor measures up to 1 Hz, but is routinely trimmean filtered to yield much lower frequency acceleration data up to 0.01 Hz. This filtered data can be mapped to arbitrary locations for characterizing the quasi-steady environment for payloads and the vehicle. The high frequency sensor is used to characterize the vibratory environment up to 100 Hz at a single measurement location. The Space Acceleration Measurement System, which deploys high frequency sensors, measures vibratory acceleration data in the range of 0.01 to 400 Hz at multiple measurement locations. This summary report presents analysis of some selected quasi-steady and vibratory activities measured by these accelerometers during Increment- 4/5 from December 2001 to December 2002.
A Framework for Monitoring Progress Using Summary Measures of Health.
Madans, Jennifer H; Weeks, Julie D
2016-10-01
Initiatives designed to monitor health typically incorporate numerous specific measures of health and the health system to assess improvements, or lack thereof, for policy and program purposes. The addition of summary measures provides overarching information which is essential for determining whether the goals of such initiatives are met. Summary measures are identified that relate to the individual indicators but that also reflect movement in the various parts of the system. A hierarchical framework that is conceptually consistent and which utilizes a succinct number of summary measures incorporating indicators of functioning and participation is proposed. While a large set of individual indicators can be useful for monitoring progress, these individual indicators do not provide an overall evaluation of health, defined broadly, at the population level. A hierarchical framework consisting of summary measures is important for monitoring the success of health improvement initiatives. © The Author(s) 2016.
Jacobson, Terry A; Ito, Matthew K; Maki, Kevin C; Orringer, Carl E; Bays, Harold E; Jones, Peter H; McKenney, James M; Grundy, Scott M; Gill, Edward A; Wild, Robert A; Wilson, Don P; Brown, W Virgil
2015-01-01
The leadership of the National Lipid Association convened an Expert Panel to develop a consensus set of recommendations for patient-centered management of dyslipidemia in clinical medicine. An Executive Summary of those recommendations was previously published. This document provides support for the recommendations outlined in the Executive Summary. The major conclusions include (1) an elevated level of cholesterol carried by circulating apolipoprotein B-containing lipoproteins (non-high-density lipoprotein cholesterol and low-density lipoprotein cholesterol [LDL-C], termed atherogenic cholesterol) is a root cause of atherosclerosis, the key underlying process contributing to most clinical atherosclerotic cardiovascular disease (ASCVD) events; (2) reducing elevated levels of atherogenic cholesterol will lower ASCVD risk in proportion to the extent that atherogenic cholesterol is reduced. This benefit is presumed to result from atherogenic cholesterol lowering through multiple modalities, including lifestyle and drug therapies; (3) the intensity of risk-reduction therapy should generally be adjusted to the patient's absolute risk for an ASCVD event; (4) atherosclerosis is a process that often begins early in life and progresses for decades before resulting a clinical ASCVD event. Therefore, both intermediate-term and long-term or lifetime risk should be considered when assessing the potential benefits and hazards of risk-reduction therapies; (5) for patients in whom lipid-lowering drug therapy is indicated, statin treatment is the primary modality for reducing ASCVD risk; (6) nonlipid ASCVD risk factors should also be managed appropriately, particularly high blood pressure, cigarette smoking, and diabetes mellitus; and (7) the measurement and monitoring of atherogenic cholesterol levels remain an important part of a comprehensive ASCVD prevention strategy. Copyright © 2015 National Lipid Association. Published by Elsevier Inc. All rights reserved.
Cherry, Gregory S.
2007-01-01
Since 1959, the U.S. Geological Survey has conducted a cooperative water resources program (CWP) with the City of Brunswick and Glynn County in the Brunswick, Georgia, area. Since the late 1950s, the salinity of ground water in the Upper Floridan aquifer near downtown Brunswick, Georgia, has been increasing, and its occurrence has been detected across an area of increasing size. Pumping of the Upper Floridan aquifer near downtown Brunswick has lowered water levels in the aquifer and resulted in an upward hydraulic gradient between the highly saline parts of the Lower Floridan aquifer and the normally fresh Upper Floridan aquifer. Saltwater likely enters the Upper Floridan aquifer through localized, vertically oriented conduits of relatively high permeability and moves laterally in response to the distribution of stresses within the aquifer. The Brunswick-Glynn County CWP for fiscal year 2006 includes the operation and maintenance of 12 continuous water-level recorders. In addition, water-level data were collected from 52 wells and water from 70 wells was analyzed for chloride concentration during June 2005. Geophysical logs were obtained from one well to assess whether the cause of elevated chloride concentration could be due to leaky well casing. A summary of the Georgia Department of Natural Resources, Environmental Protection Division (GaEPD) Georgia Coastal Sound Science Initiative (CSSI) activities that directly benefit the CWP-Brunswick-Glynn County is included in this report. The GaEPD CSSI is a program of scientific and feasibility studies to support development of a final strategy to protect the Upper Floridan aquifer from saltwater contamination. These data presented in this report are needed by State and local authorities to manage water resources effectively in the coastal area of Georgia.
Key Frame Extraction in the Summary Space.
Li, Xuelong; Zhao, Bin; Lu, Xiaoqiang; Xuelong Li; Bin Zhao; Xiaoqiang Lu; Lu, Xiaoqiang; Li, Xuelong; Zhao, Bin
2018-06-01
Key frame extraction is an efficient way to create the video summary which helps users obtain a quick comprehension of the video content. Generally, the key frames should be representative of the video content, meanwhile, diverse to reduce the redundancy. Based on the assumption that the video data are near a subspace of a high-dimensional space, a new approach, named as key frame extraction in the summary space, is proposed for key frame extraction in this paper. The proposed approach aims to find the representative frames of the video and filter out similar frames from the representative frame set. First of all, the video data are mapped to a high-dimensional space, named as summary space. Then, a new representation is learned for each frame by analyzing the intrinsic structure of the summary space. Specifically, the learned representation can reflect the representativeness of the frame, and is utilized to select representative frames. Next, the perceptual hash algorithm is employed to measure the similarity of representative frames. As a result, the key frame set is obtained after filtering out similar frames from the representative frame set. Finally, the video summary is constructed by assigning the key frames in temporal order. Additionally, the ground truth, created by filtering out similar frames from human-created summaries, is utilized to evaluate the quality of the video summary. Compared with several traditional approaches, the experimental results on 80 videos from two datasets indicate the superior performance of our approach.
Frøslie, Kathrine Frey; Røislien, Jo; Qvigstad, Elisabeth; Godang, Kristin; Bollerslev, Jens; Voldner, Nanna; Henriksen, Tore; Veierød, Marit B
2013-01-17
Plasma glucose levels are important measures in medical care and research, and are often obtained from oral glucose tolerance tests (OGTT) with repeated measurements over 2-3 hours. It is common practice to use simple summary measures of OGTT curves. However, different OGTT curves can yield similar summary measures, and information of physiological or clinical interest may be lost. Our mean aim was to extract information inherent in the shape of OGTT glucose curves, compare it with the information from simple summary measures, and explore the clinical usefulness of such information. OGTTs with five glucose measurements over two hours were recorded for 974 healthy pregnant women in their first trimester. For each woman, the five measurements were transformed into smooth OGTT glucose curves by functional data analysis (FDA), a collection of statistical methods developed specifically to analyse curve data. The essential modes of temporal variation between OGTT glucose curves were extracted by functional principal component analysis. The resultant functional principal component (FPC) scores were compared with commonly used simple summary measures: fasting and two-hour (2-h) values, area under the curve (AUC) and simple shape index (2-h minus 90-min values, or 90-min minus 60-min values). Clinical usefulness of FDA was explored by regression analyses of glucose tolerance later in pregnancy. Over 99% of the variation between individually fitted curves was expressed in the first three FPCs, interpreted physiologically as "general level" (FPC1), "time to peak" (FPC2) and "oscillations" (FPC3). FPC1 scores correlated strongly with AUC (r=0.999), but less with the other simple summary measures (-0.42≤r≤0.79). FPC2 scores gave shape information not captured by simple summary measures (-0.12≤r≤0.40). FPC2 scores, but not FPC1 nor the simple summary measures, discriminated between women who did and did not develop gestational diabetes later in pregnancy. FDA of OGTT glucose curves in early pregnancy extracted shape information that was not identified by commonly used simple summary measures. This information discriminated between women with and without gestational diabetes later in pregnancy.
A Scoping Review of Peer-led Education in Patient Safety Training
McLachlan, Andrew J.; Chen, Timothy F.
2018-01-01
Objective. To examine the literature pertaining to the use of peer-led education in patient safety. Findings. Four studies met the inclusion criteria: two were conducted in health care students and two in medical practitioners. Three studies used pre-post evaluation, with one containing a comparator group. One study a post-intervention evaluation only. All studies undertook Kirkpatrick Level 2 evaluations, showing significant improvements in attitudes and knowledge. One study undertook Level 3 and 4 evaluations, showing improvement in self-reported behaviors and engagement in quality improvement initiatives. Summary. There are few studies evaluating peer-led education in patient safety and formal and high-quality evaluations are lacking. PMID:29606704
Role of Terrestrial Wild Birds in Ecology of Influenza A Virus (H5N1)
Boon, Adrianus C.M.; Sandbulte, Matthew R.; Seiler, Patrick; Webby, Richard J.; Songserm, Thaweesak; Guan, Yi
2007-01-01
House sparrows, European starlings, and Carneux pigeons were inoculated with 4 influenza A (H5N1) viruses isolated from different avian species. We monitored viral replication, death after infection, and transmission to uninfected contact birds of the same species. Sparrows were susceptible to severe infection; 66%–100% of birds died within 4–7 days. High levels of virus were detected from oropharyngeal and cloacal swabs and in organs of deceased sparrows. Inoculation of starlings caused no deaths, despite high levels of virus shedding evident in oropharyngeal swabs. Least susceptible were pigeons, which had no deaths and very low levels of virus in oropharyngeal and cloacal swabs. Transmission to contact birds did not occur frequently: only A/common magpie/Hong Kong/645/2006 virus was shown to transmit to 1 starling. In summary, recent influenza (H5N1) viruses are pathogenic for small terrestrial bird species but the rate of intraspecies transmission in these hosts is very low. PMID:18217557
Dai, Mingwei; Ming, Jingsi; Cai, Mingxuan; Liu, Jin; Yang, Can; Wan, Xiang; Xu, Zongben
2017-09-15
Results from genome-wide association studies (GWAS) suggest that a complex phenotype is often affected by many variants with small effects, known as 'polygenicity'. Tens of thousands of samples are often required to ensure statistical power of identifying these variants with small effects. However, it is often the case that a research group can only get approval for the access to individual-level genotype data with a limited sample size (e.g. a few hundreds or thousands). Meanwhile, summary statistics generated using single-variant-based analysis are becoming publicly available. The sample sizes associated with the summary statistics datasets are usually quite large. How to make the most efficient use of existing abundant data resources largely remains an open question. In this study, we propose a statistical approach, IGESS, to increasing statistical power of identifying risk variants and improving accuracy of risk prediction by i ntegrating individual level ge notype data and s ummary s tatistics. An efficient algorithm based on variational inference is developed to handle the genome-wide analysis. Through comprehensive simulation studies, we demonstrated the advantages of IGESS over the methods which take either individual-level data or summary statistics data as input. We applied IGESS to perform integrative analysis of Crohns Disease from WTCCC and summary statistics from other studies. IGESS was able to significantly increase the statistical power of identifying risk variants and improve the risk prediction accuracy from 63.2% ( ±0.4% ) to 69.4% ( ±0.1% ) using about 240 000 variants. The IGESS software is available at https://github.com/daviddaigithub/IGESS . zbxu@xjtu.edu.cn or xwan@comp.hkbu.edu.hk or eeyang@hkbu.edu.hk. Supplementary data are available at Bioinformatics online. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com
Maternal high-fat diet and offspring expression levels of vitamin K-dependent proteins.
Lanham, S A; Cagampang, F R; Oreffo, R O C
2014-12-01
Studies suggest that bone growth and development and susceptibility to vascular disease in later life are influenced by maternal nutrition during intrauterine and early postnatal life. There is evidence for a role of vitamin K-dependent proteins (VKDPs) including osteocalcin, matrix Gla protein, periostin, and growth-arrest specific- protein 6, in both bone and vascular development. We have examined whether there are alterations in these VKDPs in bone and vascular tissue from offspring of mothers subjected to a nutritional challenge: a high-fat diet during pregnancy and postnatally, using 6-week-old mouse offspring. Bone site-specific and sex-specific differences across femoral and vertebral bone in male and female offspring were observed. Overall a high-fat maternal diet and offspring diet exacerbated the bone changes observed. Sex-specific differences and tissue-specific differences were observed in VKDP levels in aorta tissue from high-fat diet-fed female offspring from high-fat diet-fed mothers displaying increased levels of Gas6 and Ggcx compared with those of female controls. In contrast, differences were seen in VKDP levels in femoral bone of female offspring with lower expression levels of Mgp in offspring of mothers fed a high-fat diet compared with those of controls. We observed a significant correlation in Mgp expression levels within the femur to measures of bone structure of the femur and vertebra, particularly in the male offspring cohort. In summary, the current study has highlighted the importance of maternal nutrition on offspring bone development and the correlation of VKDPs to bone structure.
Zhu, Xue-Ru; Zhu, Mei-Ling; Wang, Qing; Xue, Wen-Ji; Wang, Yi-Wei; Wang, Rui-Fen; Chen, Si-Yu; Zheng, Lei-Zhen
2016-01-01
Abstract Background: Alpha-fetoprotein (AFP) is an important marker for hepatocellular carcinoma, and the detection of serum AFP is currently the principle method for the diagnosis of hepatocellular carcinoma. The prevalence of gastric cancer (GC) with high level of serum AFP is extremely rare, but has unique clinical features. Case summary: We herein present a rare case with GC and high level of serum AFP. A 64-year-old Chinese female underwent gastrectomy was diagnosed as gastric adenocarcinoma and the pathological stage was T1bN0M0, IA. With the progression of disease, the tumor widely metastasized and the serum AFP level increased progressively with the highest level of 3396 ng/mL. She successively entered into 3 lines palliative systematic chemotherapy and fourth-line targeted therapy of apatinib, a small molecule tyrosine kinase inhibitor targeting vascular endothelial growth factor receptor-2. Although previous studies suggested that the prognosis of this special type of GC was poor, this patient lived for 22 months after tumor transfer. Apatinib kept her progression-free survival for 5 months, and the overall survival was 4.5 years. Conclusion: So, we speculate that maybe we can focus apatinib on serum AFP elevated GC patients. PMID:27631210
Cardozo, Marcos J.; Massazza, Diego A.; Parkinson, John S.; Studdert, Claudia A.
2017-01-01
Summary During chemotactic signaling by Escherichia coli, the small cytoplasmic CheW protein couples the histidine kinase CheA to chemoreceptor control. Although essential for assembly and operation of receptor signaling complexes, CheW in stoichiometric excess disrupts chemotactic behavior. To explore the mechanism of the CheW excess effect, we measured the physiological consequences of high cellular levels of wild-type CheW and of several CheW variants with reduced or enhanced binding affinities for receptor molecules. We found that high levels of CheW interfered with trimer assembly, prevented CheA activation, blocked cluster formation, disrupted chemotactic ability, and elevated receptor methylation levels. The severity of these effects paralleled the receptor binding affinities of the CheW variants. Because trimer formation may be an obligate step in the assembly of ternary signaling complexes and higher-order receptor arrays, we suggest that all CheW excess effects stem from disruption of trimer assembly. We propose that the CheW-binding sites in receptor dimers overlap their trimer contact sites and that high levels of CheW saturate the receptor binding sites, preventing trimer assembly. The CheW-trapped receptor dimers seem to be improved substrates for methyltransferase reactions, but cannot activate CheA or assemble into clusters, processes that are essential for chemotactic signaling. PMID:20487303
Effects of Interspersed versus Summary Feedback on the Quality of Students' Case Report Revisions
ERIC Educational Resources Information Center
Phillips, Fred; Wolcott, Susan
2014-01-01
This study examines whether students show greater improvement in written case analyses when given feedback that is either interspersed throughout their written case analyses or presented only as a summary, and whether the benefits of these placements vary across differing levels of student performance in the course. Results from an exploratory…
Code of Federal Regulations, 2010 CFR
2010-04-01
... journey-level men and women, apprentices, and on-the-job trainees. Staffing figures to be reported in... 23 Highways 1 2010-04-01 2010-04-01 false Federal-Aid Highway Construction Summary of Employment..., DEPARTMENT OF TRANSPORTATION CIVIL RIGHTS EXTERNAL PROGRAMS Equal Employment Opportunity on Federal and...
Race to the Top. Delaware Report. Year 1: School Year 2010-2011. [State-Specific Summary Report
ERIC Educational Resources Information Center
US Department of Education, 2012
2012-01-01
This State-specific summary report serves as an assessment of Delaware's Year 1 Race to the Top implementation, highlighting successes and accomplishments, identifying challenges, and providing lessons learned from implementation to date. Delaware created new structures at the State level to support both State and LEA (local education agency) Race…
Race to the Top. North Carolina. Year 1: School Year 2010-2011. [State-Specific Summary Report
ERIC Educational Resources Information Center
US Department of Education, 2012
2012-01-01
This State-specific summary report serves as an assessment of North Carolina's Year 1 Race to the Top implementation, highlighting successes and accomplishments, identifying challenges, and providing lessons learned from implementation to date. Delaware created new structures at the State level to support both State and LEA (local education…
Results of Statewide TerraNova Testing, Fall 1998.
ERIC Educational Resources Information Center
La Marca, Paul M.
This summary provides key findings about state, district, and school level performance on the TerraNova examinations (CTB/McGraw Hill) in Nevada in 1998-1999. The TerraNova tests are used to assess students in grades 4, 8, and 10 as stipulated by Nevada law. Within this summary, a description of performance as measured by national percentile…
Beigneux, Anne P.; Davies, Brandon S. J.; Gin, Peter; Weinstein, Michael M.; Farber, Emily; Qiao, Xin; Peale, Franklin; Bunting, Stuart; Walzem, Rosemary L.; Wong, Jinny S.; Blaner, William S.; Ding, Zhi-Ming; Melford, Kristan; Wongsiriroj, Nuttaporn; Shu, Xiao; de Sauvage, Fred; Ryan, Robert O.; Fong, Loren G.; Bensadoun, André; Young, Stephen G.
2007-01-01
Summary The triglycerides in chylomicrons are hydrolyzed by lipoprotein lipase (LpL) along the luminal surface of the capillaries. However, the endothelial cell molecule that facilitates chylomicron processing by LpL has not yet been defined. Here, we show that glycosylphosphatidylinositol-anchored high density lipoprotein–binding protein 1 (GPIHBP1) plays a critical role in the lipolytic processing of chylomicrons. Gpihbp1-deficient mice exhibit a striking accumulation of chylomicrons in the plasma, even on a low-fat diet, resulting in milky plasma and plasma triglyceride levels as high as 5,000 mg/dl. Normally, Gpihbp1 is expressed highly in heart and adipose tissue, the same tissues that express high levels of LpL. In these tissues, GPIHBP1 is located on the luminal face of the capillary endothelium. Expression of GPIHBP1 in cultured cells confers the ability to bind both LpL and chylomicrons. These studies strongly suggest that GPIHBP1 is an important platform for the LpL-mediated processing of chylomicrons in capillaries. PMID:17403372
Study of a phase-to-ground fault on a 400 kV overhead transmission line
NASA Astrophysics Data System (ADS)
Iagăr, A.; Popa, G. N.; Diniş, C. M.
2018-01-01
Power utilities need to supply their consumers at high power quality level. Because the faults that occur on High-Voltage and Extra-High-Voltage transmission lines can cause serious damages in underlying transmission and distribution systems, it is important to examine each fault in detail. In this work we studied a phase-to-ground fault (on phase 1) of 400 kV overhead transmission line Mintia-Arad. Indactic® 650 fault analyzing system was used to record the history of the fault. Signals (analog and digital) recorded by Indactic® 650 were visualized and analyzed by Focus program. Summary of fault report allowed evaluation of behavior of control and protection equipment and determination of cause and location of the fault.
DiffNet: automatic differential functional summarization of dE-MAP networks.
Seah, Boon-Siew; Bhowmick, Sourav S; Dewey, C Forbes
2014-10-01
The study of genetic interaction networks that respond to changing conditions is an emerging research problem. Recently, Bandyopadhyay et al. (2010) proposed a technique to construct a differential network (dE-MAPnetwork) from two static gene interaction networks in order to map the interaction differences between them under environment or condition change (e.g., DNA-damaging agent). This differential network is then manually analyzed to conclude that DNA repair is differentially effected by the condition change. Unfortunately, manual construction of differential functional summary from a dE-MAP network that summarizes all pertinent functional responses is time-consuming, laborious and error-prone, impeding large-scale analysis on it. To this end, we propose DiffNet, a novel data-driven algorithm that leverages Gene Ontology (go) annotations to automatically summarize a dE-MAP network to obtain a high-level map of functional responses due to condition change. We tested DiffNet on the dynamic interaction networks following MMS treatment and demonstrated the superiority of our approach in generating differential functional summaries compared to state-of-the-art graph clustering methods. We studied the effects of parameters in DiffNet in controlling the quality of the summary. We also performed a case study that illustrates its utility. Copyright © 2014 Elsevier Inc. All rights reserved.
Wunderlich, Adam; Abbey, Craig K
2013-11-01
Studies of lesion detectability are often carried out to evaluate medical imaging technology. For such studies, several approaches have been proposed to measure observer performance, such as the receiver operating characteristic (ROC), the localization ROC (LROC), the free-response ROC (FROC), the alternative free-response ROC (AFROC), and the exponentially transformed FROC (EFROC) paradigms. Therefore, an experimenter seeking to carry out such a study is confronted with an array of choices. Traditionally, arguments for different approaches have been made on the basis of practical considerations (statistical power, etc.) or the gross level of analysis (case-level or lesion-level). This article contends that a careful consideration of utility should form the rationale for matching the assessment paradigm to the clinical task of interest. In utility theory, task performance is commonly evaluated with total expected utility, which integrates the various event utilities against the probability of each event. To formalize the relationship between expected utility and the summary curve associated with each assessment paradigm, the concept of a "natural" utility structure is proposed. A natural utility structure is defined for a summary curve when the variables associated with the summary curve axes are sufficient for computing total expected utility, assuming that the disease prevalence is known. Natural utility structures for ROC, LROC, FROC, AFROC, and EFROC curves are introduced, clarifying how the utilities of correct and incorrect decisions are aggregated by summary curves. Further, conditions are given under which general utility structures for localization-based methodologies reduce to case-based assessment. Overall, the findings reveal how summary curves correspond to natural utility structures of diagnostic tasks, suggesting utility as a motivating principle for choosing an assessment paradigm.
ERIC Educational Resources Information Center
Sanchez, Maria Teresa; Ehrlich, Stacy; Midouhas, Emily; O'Dwyer, Laura
2009-01-01
Massachusetts policymakers have expressed concern about the consistently lower scores of Hispanic students, compared to other subgroups, on the Massachusetts Comprehensive Assessment System (MCAS). This summary describes a larger report that examines Hispanic high school students' performance on the MCAS tests in English language arts and…
Salvatore, Stefania; Bramness, Jørgen Gustav; Reid, Malcolm J; Thomas, Kevin Victor; Harman, Christopher; Røislien, Jo
2015-01-01
Wastewater-based epidemiology (WBE) is a new methodology for estimating the drug load in a population. Simple summary statistics and specification tests have typically been used to analyze WBE data, comparing differences between weekday and weekend loads. Such standard statistical methods may, however, overlook important nuanced information in the data. In this study, we apply functional data analysis (FDA) to WBE data and compare the results to those obtained from more traditional summary measures. We analysed temporal WBE data from 42 European cities, using sewage samples collected daily for one week in March 2013. For each city, the main temporal features of two selected drugs were extracted using functional principal component (FPC) analysis, along with simpler measures such as the area under the curve (AUC). The individual cities' scores on each of the temporal FPCs were then used as outcome variables in multiple linear regression analysis with various city and country characteristics as predictors. The results were compared to those of functional analysis of variance (FANOVA). The three first FPCs explained more than 99% of the temporal variation. The first component (FPC1) represented the level of the drug load, while the second and third temporal components represented the level and the timing of a weekend peak. AUC was highly correlated with FPC1, but other temporal characteristic were not captured by the simple summary measures. FANOVA was less flexible than the FPCA-based regression, and even showed concordance results. Geographical location was the main predictor for the general level of the drug load. FDA of WBE data extracts more detailed information about drug load patterns during the week which are not identified by more traditional statistical methods. Results also suggest that regression based on FPC results is a valuable addition to FANOVA for estimating associations between temporal patterns and covariate information.
Van Straten, S K; Stannard, C J; Bulabula, J; Paul, K; Leong, J; Klipin, M
2017-06-01
South Africa has an overburdened public healthcare system. Some admissions to Charlotte Maxeke Johannesburg Academic Hospital (CMJAH) may not require tertiary care. The numbers and details thereof are uncertain. Clinical research is limited by skills and access to data. A retrospective analysis of Electronic Discharge (ED) summaries from the Department of Surgery at CMJAH between 01 April 2015 and 01 April 2016. An SQL-query of the database generated a .csv file of all discharges with the fields database reference number, length of stay and level of care. The details and level of care of each record were verified by MBBCh 5 medical students using a defined level of care template with review of the full discharge summary. The data was reviewed by a senior clinician. There were 3007 discharge summaries, 97 were not classifiable, two were test records and one was a duplicate. These 100 records were excluded. There were no primary level records. Secondary level patients represented 29% (854) of patients discharged and 19% of total bed days. Tertiary and quaternary together represented 71% of the total patients and 81% of bed days. The average length of stay was 4.31 days for secondary, 6.98 days for tertiary and 9.77 days for quaternary level of care allocation. Almost a third (29%) of patients discharged from CMJAH Department of Surgery were deemed suitable for secondary level care. These admissions have a shorter length of stay and comprise 19% of total bed days. Students and electronic databases are useful research resources.
From image captioning to video summary using deep recurrent networks and unsupervised segmentation
NASA Astrophysics Data System (ADS)
Morosanu, Bogdan-Andrei; Lemnaru, Camelia
2018-04-01
Automatic captioning systems based on recurrent neural networks have been tremendously successful at providing realistic natural language captions for complex and varied image data. We explore methods for adapting existing models trained on large image caption data sets to a similar problem, that of summarising videos using natural language descriptions and frame selection. These architectures create internal high level representations of the input image that can be used to define probability distributions and distance metrics on these distributions. Specifically, we interpret each hidden unit inside a layer of the caption model as representing the un-normalised log probability of some unknown image feature of interest for the caption generation process. We can then apply well understood statistical divergence measures to express the difference between images and create an unsupervised segmentation of video frames, classifying consecutive images of low divergence as belonging to the same context, and those of high divergence as belonging to different contexts. To provide a final summary of the video, we provide a group of selected frames and a text description accompanying them, allowing a user to perform a quick exploration of large unlabeled video databases.
Depletion of GGA3 stabilizes BACE and enhances β-secretase activity
Tesco, Giuseppina; Koh, Young Ho; Kang, Eugene; Cameron, Andrew; Das, Shinjita; Sena-Esteves, Miguel; Hiltunen, Mikko; Yang, Shao-Hua; Zhong, Zhenyu; Shen, Yong; Simpkins, James; Tanzi, Rudolph E.
2007-01-01
Summary Beta-site APP-cleaving enzyme (BACE) is required for production of the Alzheimer's disease (AD)-associated Aβ protein. BACE levels are elevated in AD brain, and increasing evidence reveals BACE as a stress-related protease that is upregulated following cerebral ischemia. However, the molecular mechanism responsible is unknown. We show that increases in BACE and β-secretase activity are due to post-translational stabilization following caspase activation. We also found that during cerebral ischemia, levels of GGA3, an adaptor protein involved in BACE trafficking, are reduced, while BACE levels are increased. RNAi silencing of GGA3 also elevated levels of BACE and Aβ. Finally, in AD brain samples, GGA3 protein levels were significantly decreased and inversely correlated with increased levels of BACE. In summary, we have elucidated a novel GGA3-dependent mechanism regulating BACE levels and β-secretase activity. This mechanism may explain increased cerebral levels of BACE and Aβ following cerebral ischemia and in AD. PMID:17553422
Foster, Scott D.; Griffin, David A.; Dunstan, Piers K.
2014-01-01
The physical climate defines a significant portion of the habitats in which biological communities and species reside. It is important to quantify these environmental conditions, and how they have changed, as this will inform future efforts to study many natural systems. In this article, we present the results of a statistical summary of the variability in sea surface temperature (SST) time-series data for the waters surrounding Australia, from 1993 to 2013. We partition variation in the SST series into annual trends, inter-annual trends, and a number of components of random variation. We utilise satellite data and validate the statistical summary from these data to summaries of data from long-term monitoring stations and from the global drifter program. The spatially dense results, available as maps from the Australian Oceanographic Data Network's data portal (http://www.cmar.csiro.au/geonetwork/srv/en/metadata.show?id=51805), show clear trends that associate with oceanographic features. Noteworthy oceanographic features include: average warming was greatest off southern West Australia and off eastern Tasmania, where the warming was around 0.6°C per decade for a twenty year study period, and insubstantial warming in areas dominated by the East Australian Current, but this area did exhibit high levels of inter-annual variability (long-term trend increases and decreases but does not increase on average). The results of the analyses can be directly incorporated into (biogeographic) models that explain variation in biological data where both biological and environmental data are on a fine scale. PMID:24988444
Quality of life in children with new-onset epilepsy
Ferro, Mark A.; Camfield, Carol S.; Huang, Wenyi; Levin, Simon D.; Smith, Mary Lou; Wiebe, Samuel; Zou, Guangyong
2012-01-01
Objectives: To assess health-related quality of life (HRQL) over 2 years in children 4−12 years old with new-onset epilepsy and risk factors. Methods: Data are from a multicenter prospective cohort study, the Health-Related Quality of Life Study in Children with Epilepsy Study (HERQULES). Parents reported on children's HRQL and family factors and neurologists on clinical characteristics 4 times. Mean subscale and summary scores were computed for HRQL. Individual growth curve models identified trajectories of change in HRQL scores. Multiple regression identified baseline risk factors for HRQL 2 years later. Results: A total of 374 (82) questionnaires were returned postdiagnosis and 283 (62%) of eligible parents completed all 4. Growth rates for HRQL summary scores were most rapid during the first 6 months and then stabilized. About one-half experienced clinically meaningful improvements in HRQL, one-third maintained their same level, and one-fifth declined. Compared with the general population, at 2 years our sample scored significantly lower on one-third of CHQ subscales and the psychosocial summary. After controlling for baseline HRQL, cognitive problems, poor family functioning, and high family demands were risk factors for poor HRQL 2 years later. Conclusions: On average, HRQL was relatively good but with highly variable individual trajectories. At least one-half did not experience clinically meaningful improvements or declined over 2 years. Cognitive problems were the strongest risk factor for compromised HRQL 2 years after diagnosis and may be largely responsible for declines in the HRQL of children newly diagnosed with epilepsy. PMID:23019268
Xu, Q; Fu, H H; Gupta, R; Luan, S
1998-01-01
Protein tyrosine kinases and phosphatases play a vital role in the regulation of cell growth and differentiation in animal systems. However, none of these enzymes has been characterized from higher plants. In this study, we isolated a cDNA encoding a putative protein tyrosine phosphatase (PTPase) from Arabidopsis (referred to as AtPTP1). The expression level of AtPTP1 is highly sensitive to environmental stresses. High-salt conditions increased AtPTP1 mRNA levels, whereas cold treatment rapidly eliminated the AtPTP1 transcript. The recombinant AtPTP1 protein specifically hydrolyzed phosphotyrosine, but not phosphoserine/threonine, in protein substrates. Site-directed mutagenesis defined two highly conserved amino acids, cysteine-265 and aspartate-234, as being essential for the phosphatase activity of the AtPTP1 protein, suggesting a common catalytic mechanism for PTPases from all eukaryotic systems. In summary, we have identified AtPTP1 as a tyrosine-specific protein phosphatase that may function in stress responses of higher plants. PMID:9596642
ERIC Educational Resources Information Center
International Student Pugwash, Washington, DC.
Proceedings of a symposium which focused on issues related to nuclear weapons and arms control are presented. In addition to a list of participants (including both high school and college educators) and symposium schedule, summaries/highlights of symposium sessions are provided. These include summaries of three working groups which discussed…
The first national clinical audit for rheumatoid arthritis.
Firth, J; Snowden, N; Ledingham, J; Rivett, A; Galloway, J; Dennison, E M; MacPhie, E; Ide, Z; Rowe, I; Kandala, N; Jameson, K
The first national audit for rheumatoid and early inflammatory arthritis has benchmarked care for the first 3 months of follow-up activity from first presentation to a rheumatology service. Access to care, management of early rheumatoid arthritis and support for self care were measured against National Institute for Health and Care Excellence quality standards; impact of early arthritis and experience of care were measured using patient-reported outcome and experience measures. The results demonstrate delays in referral and accessing specialist care and the need for service improvement in treating to target, suppression of high levels of disease activity and support for self-care. Improvements in patient-reported outcomes within 3 months and high levels of overall satisfaction were reported but these results were affected by low response rates. This article presents a summary of the national data from the audit and discusses the implications for nursing practice.
Utazi, C Edson; Thorley, Julia; Alegana, Victor A; Ferrari, Matthew J; Takahashi, Saki; Metcalf, C Jessica E; Lessler, Justin; Tatem, Andrew J
2018-03-14
The expansion of childhood vaccination programs in low and middle income countries has been a substantial public health success story. Indicators of the performance of intervention programmes such as coverage levels and numbers covered are typically measured through national statistics or at the scale of large regions due to survey design, administrative convenience or operational limitations. These mask heterogeneities and 'coldspots' of low coverage that may allow diseases to persist, even if overall coverage is high. Hence, to decrease inequities and accelerate progress towards disease elimination goals, fine-scale variation in coverage should be better characterized. Using measles as an example, cluster-level Demographic and Health Surveys (DHS) data were used to map vaccination coverage at 1 km spatial resolution in Cambodia, Mozambique and Nigeria for varying age-group categories of children under five years, using Bayesian geostatistical techniques built on a suite of publicly available geospatial covariates and implemented via Markov Chain Monte Carlo (MCMC) methods. Measles vaccination coverage was found to be strongly predicted by just 4-5 covariates in geostatistical models, with remoteness consistently selected as a key variable. The output 1 × 1 km maps revealed significant heterogeneities within the three countries that were not captured using province-level summaries. Integration with population data showed that at the time of the surveys, few districts attained the 80% coverage, that is one component of the WHO Global Vaccine Action Plan 2020 targets. The elimination of vaccine-preventable diseases requires a strong evidence base to guide strategies and inform efficient use of limited resources. The approaches outlined here provide a route to moving beyond large area summaries of vaccination coverage that mask epidemiologically-important heterogeneities to detailed maps that capture subnational vulnerabilities. The output datasets are built on open data and methods, and in flexible format that can be aggregated to more operationally-relevant administrative unit levels. Copyright © 2018 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Dissecting the genetics of complex traits using summary association statistics.
Pasaniuc, Bogdan; Price, Alkes L
2017-02-01
During the past decade, genome-wide association studies (GWAS) have been used to successfully identify tens of thousands of genetic variants associated with complex traits and diseases. These studies have produced extensive repositories of genetic variation and trait measurements across large numbers of individuals, providing tremendous opportunities for further analyses. However, privacy concerns and other logistical considerations often limit access to individual-level genetic data, motivating the development of methods that analyse summary association statistics. Here, we review recent progress on statistical methods that leverage summary association data to gain insights into the genetic basis of complex traits and diseases.
Dissecting the genetics of complex traits using summary association statistics
Pasaniuc, Bogdan; Price, Alkes L.
2017-01-01
During the past decade, genome-wide association studies (GWAS) have successfully identified tens of thousands of genetic variants associated with complex traits and diseases. These studies have produced extensive repositories of genetic variation and trait measurements across large numbers of individuals, providing tremendous opportunities for further analyses. However, privacy concerns and other logistical considerations often limit access to individual-level genetic data, motivating the development of methods that analyze summary association statistics. Here we review recent progress on statistical methods that leverage summary association data to gain insights into the genetic basis of complex traits and diseases. PMID:27840428
Noise peaks influence communication in the operating room. An observational study.
Keller, Sandra; Tschan, Franziska; Beldi, Guido; Kurmann, Anita; Candinas, Daniel; Semmer, Norbert K
2016-12-01
Noise peaks are powerful distractors. This study focuses on the impact of noise peaks on surgical teams' communication during 109 long abdominal surgeries. We related measured noise peaks during 5-min intervals to the amount of observed communication during the same interval. Results show that noise peaks are associated with less case-relevant communication; this effect is moderated by the level of surgical experience; case-relevant communications decrease under high noise peak conditions among junior, but not among senior surgeons. However, case-irrelevant communication did not decrease under high noise level conditions, rather there was a trend to more case-irrelevant communication under high noise peaks. The results support the hypothesis that noise peaks impair communication because they draw on attentional resources rather than impairing understanding of communication. As case-relevant communication is important for surgical performance, exposure to high noise peaks in the OR should be minimised especially for less experienced surgeons. Practitioner Summary: This study investigated whether noise during surgeries influenced the communication within surgical teams. During abdominal surgeries, noise levels were measured and communication was observed. Results showed that high noise peaks reduced the frequency of patient-related communication, but did not reduce patient-irrelevant communication. Noise may negatively affect team coordination in surgeries.
2008 technical workshop regarding development of additional guidelines or best practices for planning, implementing and interpreting ecological risk assessments that involve population-level assessment endpoints.
E2E: A Summary of the e2e Learning Framework.
ERIC Educational Resources Information Center
Learning and Skills Development Agency, London (England).
This publication is a summary of the E2E (Entry to Employment) Learning Framework that provides guidance on program implementation. (E2E is a new learning program for young people not yet ready or able to enter Modern Apprenticeship programs, a Level 2 program, or employment directly.) Section 2 highlights core values to which all involved should…
ERIC Educational Resources Information Center
Bureau of the Census (DOC), Suitland, MD.
This report presents a summary of recent trends in school and college enrollment based on the October 1977 Current Population Survey (CPS) and earlier surveys. Enrollment statistics representing growth and decline at various educational levels are evaluated in written summaries. Comparative and distributive enrollment statistics of the population…
Project Summary and Conclusions
NASA Technical Reports Server (NTRS)
Sawin, Charles
1999-01-01
A top level summary of activities conducted throughout the course of the EDOMP in response to initial concerns at the outset of the program is provided. Significant findings from the investigations are summarized, together with resulting countermeasures that were implemented and flight rules that were developed in response to these findings. Subsequent paragraphs provide more information; details will be found in the referenced sections.
Household Hazardous Waste Disposal Project. Summary Report. Metro Toxicant Program Report No. 1A.
ERIC Educational Resources Information Center
Ridgley, Susan M.; Galvin, David V.
The Household Hazardous Waste Disposal Project was established as an interagency effort to reduce the level of toxicants entering the environment by developing a control plan for the safe disposal of small quantities of household chemicals. This summary report provides an overview of the aspects of this problem that were examined, and the steps…
Real-Time Aggressive Image Data Compression
1990-03-31
implemented with higher degrees of modularity, concurrency, and higher levels of machine intelligence , thereby providing higher data -throughput rates...Project Summary Project Title: Real-Time Aggressive Image Data Compression Principal Investigators: Dr. Yih-Fang Huang and Dr. Ruey-wen Liu Institution...Summary The objective of the proposed research is to develop reliable algorithms !.hat can achieve aggressive image data compression (with a compression
Deng, Yangqing; Pan, Wei
2018-06-01
Due to issues of practicality and confidentiality of genomic data sharing on a large scale, typically only meta- or mega-analyzed genome-wide association study (GWAS) summary data, not individual-level data, are publicly available. Reanalyses of such GWAS summary data for a wide range of applications have become more and more common and useful, which often require the use of an external reference panel with individual-level genotypic data to infer linkage disequilibrium (LD) among genetic variants. However, with a small sample size in only hundreds, as for the most popular 1000 Genomes Project European sample, estimation errors for LD are not negligible, leading to often dramatically increased numbers of false positives in subsequent analyses of GWAS summary data. To alleviate the problem in the context of association testing for a group of SNPs, we propose an alternative estimator of the covariance matrix with an idea similar to multiple imputation. We use numerical examples based on both simulated and real data to demonstrate the severe problem with the use of the 1000 Genomes Project reference panels, and the improved performance of our new approach. Copyright © 2018 by the Genetics Society of America.
Diamond Pixel Luminosity Telescopes
DOE Office of Scientific and Technical Information (OSTI.GOV)
Halyo, Valerie
2014-12-15
In this document, Halyo summaries her key contributions to CMS at the LHC and provide an explanation of their importance and her role in each project. At the end Halyo describes her recent research interest that includes GPU/MIC Acceleration of the High Level Trigger (HLT) to Extend the Physics Research at the LHC. A description of her work the recent promising results that she accomplished and the deliverable are also elaborated. These contribution were only possible thanks to DOE support of junior faculty research and their clear goal to promote research and innovations.
Summary of Research, Academic Departments, 1983-1984.
1984-10-01
miagnetoelast ic strain gauiges. hydraulic (ollrols svsteiiis, robotics, aiiol gas tul-ili( engine (lilic(’. Th’lis wear, e’Ii phasis has beent placed...gatige, the( gifligV id~ itsSsigiifI Co(lifltioflihlg. High Level Real-Time Software for Hydraulic Control Systems in Deep Submergence Vehicles h~iSiAt...Simulation of a Hydraulic Control System At )VISUMt: ASSOCIATII PiiOtISSOt1 IAIU IIB V. I I)L SKA\\ Theo Jriluialrv pourpose of’ this l’C51’drch is to) wxIihi
CHEMICAL ENGINEERING DIVISION SUMMARY REPORT, OCTOBER, NOVEMBER, DECEMBER 1960
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
1961-03-01
Chemical-metallurgical processing studies were made of pyrometallurgical development snd research, and fuel processing facilities for EBR-II. Fuel-cycle applications of fluidization and volatility techniques included laboratory investigations of fluoride volatility processes, engineeringscale development, and conversion of UF/sub 6/ to UO/sub 2/. Reactor safety studies consisted of metal oxidation and ignition kinetics, and metal-water reactions. Reactor chemistry investigations were conducted to determine nuclear constants and suitable reactor decontamination methods. Routine operations are summarized for the high-level gammairradiation facillty and waste processing. (B.O.G.)
ERIC Educational Resources Information Center
Deutsch, Morton
This paper is a summary report of a study of the effects of training in conflict resolution and cooperative learning in an alternative high school in New York City. Three of the school's four campuses participated, with Campus A receiving conflict resolution training, Campus C receiving cooperative learning training, and Campus B receiving…
An Opportunity Culture "for All": Making Teaching a Highly Paid, High-Impact Profession. Summary
ERIC Educational Resources Information Center
Hassel, Emily Ayscue; Hassel, Bryan C.
2013-01-01
In this summary, authors and co-directors of "Public Impact," Emily Ayscue Hassel and Bryan C. Hassel, state that, in most locations, the relationship between organized teachers and reformers remains at best a tenuous truce and at worst a pitched battle. None are really getting what they want. Teachers are no closer to achieving the…
ERIC Educational Resources Information Center
Fortner, Rosanne W., Ed.; Mayer, Victor J., Ed.
This volume contains the proceedings and summary for the Earth Systems Education high school symposium conducted in October, 1994. Selected participants were invited to contribute papers for inclusion in this volume so that other teachers can see how Earth Systems Education (ESE) looks in practice. The volume also contains the context for ESE in…
Epidemiology of osteoarthritis: state of the evidence
Allen, Kelli D.; Golightly, Yvonne M.
2015-01-01
Purpose of review This review focuses on recent studies of osteoarthritis epidemiology, including research on prevalence, incidence, and a broad array of potential risk factors at the person level and joint level. Recent findings Studies continue to illustrate the high impact of osteoarthritis worldwide, with increasing incidence. Person-level risk factors with strong evidence regarding osteoarthritis incidence and/or progression include age, sex, socioeconomic status, family history, and obesity. Joint-level risk factors with strong evidence for incident osteoarthritis risk include injury and occupational joint loading; the associations of injury and joint alignment with osteoarthritis progression are compelling. Moderate levels of physical activity have not been linked to increased osteoarthritis risk. Some topics of high recent interest or emerging evidence for association with osteoarthritis include metabolic pathways, vitamins, joint shape, bone density, limb length inequality, muscle strength and mass, and early structural damage. Summary Osteoarthritis is a complex, multifactorial disease, and there is still much to learn regarding mechanisms underlying incidence and progression. However, there are several known modifiable and preventable risk factors, including obesity and joint injury; efforts to mitigate these risks can help to lessen the impact of osteoarthritis. PMID:25775186
Self-report of diabetes and claims-based identification of diabetes among Medicare beneficiaries.
Day, Hannah R; Parker, Jennifer D
2013-11-01
This report compares self-reported diabetes in the National Health Interview Survey (NHIS) with diabetes identified using the Medicare Chronic Condition (CC) Summary file. NHIS records have been linked with Medicare data from the Centers for Medicare & Medicaid Services. The CC Summary file, one of several linked files derived from Medicare claims data, contains indicators for chronic conditions based on an established algorithm. This analysis was limited to 2005 NHIS participants aged 65 and over whose records were linked to 2005 Medicare data. Linked NHIS participants had at least 1 month of fee-for-service Medicare coverage in 2005. Concordance between self-reported diabetes and the CC Summary indicator for diabetes is compared and described by demographics, socioeconomic status, health status indicators, and geographic characteristics. Of the Medicare beneficiaries in the 2005 NHIS, 20.0% self-reported diabetes and 27.8% had an indicator for diabetes in the CC Summary file. Of those who self-reported diabetes in NHIS, the percentage with a CC Summary indicator for diabetes was high (93.1%). Of those with a CC Summary indicator for diabetes, the percentage self-reporting diabetes was comparatively lower (67.0%). Statistically significant differences by subgroup existed in the percentage concordance between the two sources. Of those with self-reported diabetes, the percentage with a CC Summary indicator differed by sex and age. Of those with a CC Summary indicator for diabetes, the percentage with self-reported diabetes differed by age, self-rated health, number of self-reported conditions, and geographic location. Among Medicare beneficiaries who self-reported diabetes in NHIS, a high concordance was observed with identification of diabetes in the CC Summary file. However, among Medicare beneficiaries with an indicator for diabetes in the CC Summary file, concordance with self-reported diabetes in NHIS is comparatively lower. Differences exist by subgroup.
Dietrich, Sascha; Okun, Jürgen G.; Schmidt, Kathrin; Falk, Christine S.; Wagner, Andreas H.; Karamustafa, Suzan; Radujkovic, Aleksandar; Hegenbart, Ute; Ho, Anthony D.; Dreger, Peter; Luft, Thomas
2014-01-01
Steroid-refractory graft-versus-host disease is a life-threatening complication after allogeneic stem cell transplantation. Evidence is accumulating that steroid-refractory graft-versus-host disease is associated with endothelial distress. Endothelial cell homeostasis is regulated by nitric oxide, and serum nitrates are derived from nitric oxide synthase activity or dietary sources. In this retrospective study based on 417 patients allografted at our institution we investigated whether quantification of serum nitrates could predict steroid-refractory graft-versus-host disease. Elevated pre-transplant levels of serum nitrates (>26.5 μM) predicted steroid-refractory graft-versus-host disease (P=0.026) and non-relapse mortality (P=0.028), particularly in combination with high pre-transplant angiopoietin-2 levels (P=0.0007 and P=0.021, respectively). Multivariate analyses confirmed serum nitrates as independent predictors of steroid-refractory graft-versus-host disease and non-relapse mortality. Differences in serum nitrate levels did not correlate with serum levels of tumor necrosis factor or C-reactive protein or expression of inducible nitric oxide synthase in blood cells. Patients with high pre-transplant nitrate levels had significantly reduced rates of refractory graft-versus-host disease (P=0.031) when pravastatin was taken. In summary, patients at high risk of developing steroid-refractory graft-versus-host disease could be identified prior to transplantation by serum markers linked to endothelial cell function. Retrospectively, statin medication was associated with a reduced incidence of refractory graft-versus-host disease in this endothelial high-risk cohort. PMID:24142995
California Alliance For Radiotracer Education, CARE
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sutcliffe, Julie
The report contains a summary of the accomplishments made during the CARE proposal. The overall goal of this proposal was to train graduate students and postdoctoral fellows in the field of radiochemistry. The goal was to expose trainees to the fundamentals of radioisotope production, radiochemistry synthesis, synthetic organic chemistry as well as applications and hands on experience in small animal imaging. In summary approximately 30 trainees were involved including trainees both at the graduate and postdoctoral levels. This funding has to date resulted in publications in high impact journals such as Med Chem Comm, Journal of Nuclear Medicine and Molecularmore » Imaging and Biology. Trainees have gone on to further their careers in both academia, industry and the private sector. The funding will result in seven Master’s and six Ph.D dissertations. Without the DOE funding it simply would not have been possible to continue to train the next generation of radiochemists needed to assure a future US-based Nuclear and Radiochemistry Expertise.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Barner, J.O.; Cunningham, M.E.; Freshley, M.D.
1990-04-01
This is the final report of the High Burnup Effects Program (HBEP). It has been prepared to present a summary, with conclusions, of the HBEP. The HBEP was an international, group-sponsored research program managed by Battelle, Pacific Northwest Laboratories (BNW). The principal objective of the HBEP was to obtain well-characterized data related to fission gas release (FGR) for light water reactor (LWR) fuel irradiated to high burnup levels. The HBEP was organized into three tasks as follows: Task 1 -- high burnup effects evaluations; Task 2 -- fission gas sampling; and Task 3 -- parameter effects study. During the coursemore » of the HBEP, a program that extended over 10 years, 82 fuel rods from a variety of sources were characterized, irradiated, and then examined in detail after irradiation. The study of fission gas release at high burnup levels was the principal objective of the program and it may be concluded that no significant enhancement of fission gas release at high burnup levels was observed for the examined rods. The rim effect, an as yet unquantified contributor to athermal fission gas release, was concluded to be the one truly high-burnup effect. Though burnup enhancement of fission gas release was observed to be low, a full understanding of the rim region and rim effect has not yet emerged and this may be a potential area of further research. 25 refs., 23 figs., 4 tabs.« less
Xu, Dongjuan; Kane, Robert L; Shippee, Tetyana; Lewis, Teresa M
2016-12-01
There is a general belief that the markers of nursing home quality do not aggregate easily. Identifying consistent and coherent dimensions of quality that usefully summarize the multiplicity of nursing home quality measures is an important goal. It would simplify interpretation and help consumers, their families and advocates to choose nursing facilities. This study uses quality indicators (QIs) from a state nursing home report card to explore the dimensionality of quality in nursing homes and to determine whether aggregation at the resident versus facility level yields the same underlying dimensions. Cross-sectional study. 382 Medicare- and/or Medicaid-certified nursing homes in Minnesota. Residents admitted to the nursing homes during 2011-2012. 16 QIs obtained from the Minimum Data Set 3.0 assessment instrument between 2011 and 2012 were used in the exploratory factor analysis. Factor analysis results suggest four main factors or dimensions to characterize facility performance: continence care (including 4 QIs), restraints and behavioral symptoms (including 3 QIs), care for specific conditions (including 6 QIs), and physical functioning (including 3 QIs). The resident-level and facility-level results generally agreed for 11 QIs. Nursing home quality of care can be captured in summary measures, which can be used by consumers, providers and researchers. Reporting at the resident or facility level will depend on the purpose. These summary measures can be used by policy-makers to identify and reward high-performing facilities and by families to choose nursing facilities for care. © 2016, Copyright the Authors Journal compilation © 2016, The American Geriatrics Society.
Renewable Electricity Futures Study Executive Summary
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mai, Trieu; Sandor, Debra; Wiser, Ryan
2012-12-01
The Renewable Electricity Futures Study (RE Futures) provides an analysis of the grid integration opportunities, challenges, and implications of high levels of renewable electricity generation for the U.S. electric system. The study is not a market or policy assessment. Rather, RE Futures examines renewable energy resources and many technical issues related to the operability of the U.S. electricity grid, and provides initial answers to important questions about the integration of high penetrations of renewable electricity technologies from a national perspective. RE Futures results indicate that a future U.S. electricity system that is largely powered by renewable sources is possible andmore » that further work is warranted to investigate this clean generation pathway.« less
Laktić, Martina; Kuftinec, Krešimir; Čelebić, Asja; Kovačić, Ines; Alhajj, Mohamed Nasser
2017-01-01
Objective To develop the Croatian version of the 41-item Dental Environment Stress questionnaire (DES) for stress assessment of dental students in both, preclinical and clinical years of study and to test its psychometric properties in Croatian dental student population. Materials and Methods The English version of the 41-Item DES questionnaire was first translated into the Croatian language. Subsequently, it was set on the google drive and filled out by a total of 202 students from the School of Dental Medicine, University of Zagreb and 30 additional students from other Faculties. Students also assessed their overall level of stress on the Likert scale (1=no stress, 5=highest level of stress). Internal consistency was tested on 202 dental students; test-retest reliability on 30 dental students who filled out the same questionnaire twice; convergent validity on 202 dental students; and divergent validity on 202 dental students and 30 students from faculties not belonging to the biomedicine group. Results Internal consistency showed high Cronbach alpha coefficient (0.9) and test-retest reliability showed no significant difference (P>0.05) within the period of 14 days when stress level had not changed (vacation). Convergent validity was confirmed by the significant association between the DES summary scores and the self- perceived level of stress (Spearman’s rho=0.881; P<0.001). Divergent validity was confirmed by significantly lower DES summary scores in students not belonging to the Biomedicine group (t=7.5, P<0.001). Conclusion Excellent psychometric properties of the Croatian version of the DES questionnaire enable its utilization for assessment of stress level in Croatian dental students. PMID:29225359
Dumoulin, Chantale; Hunter, Kathleen F; Moore, Katherine; Bradley, Catherine S; Burgio, Kathryn L; Hagen, S; Imamura, M; Thakar, R; Williams, K; Chambers, T
2016-01-01
The objective of the 5th International Consultation on Incontinence (ICI) chapter on Adult Conservative Management was to review and summarize the new evidence on conservative management of urinary incontinence (UI) and pelvic organ prolapse (POP) in order to compile a current reference source for clinicians, health researchers, and service planners. In this paper, we present the review highlights and new evidence on female conservative management. Revision and updates of the 4th ICI Report using systematic review covering years 2008-2012. Each section begins with a brief definition and description of the intervention followed by a summary, where possible, of both the state and level of evidence for prevention and treatment, and ends with a "grade of recommendation." The paper concludes with areas identified as requiring further research. For UI, there are no prevention trials on lifestyle interventions. There are, however, few new intervention trials of lifestyle interventions involving weight loss and fluid intake with improved levels of evidence and grade of recommendation. Outside of pre- and post-natal pelvic floor muscle training (PFMT) trials for the prevention of female UI, there is a dearth of PFMT prevention trials for women with UI. PFMT remains the first-line treatment for female UI with high levels of evidence and grades of recommendation. Bladder training levels of evidence and grades of recommendation are maintained. For POP, new evidence supports the effectiveness of physiotherapy in the treatment of POP and there are now improved levels of evidence and grades of recommendation. Neurourol. Urodynam. 35:15-20, 2016. © 2014 Wiley Periodicals, Inc. © 2014 Wiley Periodicals, Inc.
NASA Remediation Technology Collaboration Development Task, Overview and Project Summaries
NASA Technical Reports Server (NTRS)
Romeo, James G.
2014-01-01
An overview presentation of NASA's Remediation Technology Collaboration Development Task including the following project summaries: in situ groundwater monitor, in situ chemical oxidation, in situ bioremediation, horizontal multi-port well, and high resolution site characterization.
Processing, Properties and Arc Jet Testing of HfB2/SiC
NASA Technical Reports Server (NTRS)
Johnson, Sylvia M.; Beckman, Sarah; Irby, Edward; Ellerby, Don; Gasch, Matt; Gusman, Michael
2004-01-01
Contents include the following: Background on Ultra High Temperature Ceramics - UHTCs. Summary UNTC processing: power processing, scale-up. Preliminary material properties: mechanical, thermal. Arc jet testing: flat face models, cone models. Summary.
Persistent HyperCKemia in Athletes
Brancaccio, Paola; Maffulli, Nicola; Politano, Luisa; Lippi, Giuseppe; Limongelli, Francesco Mario
2011-01-01
Summary We compared the effects of exercise on serum levels of creatin kinase (CK) in athletes with persistent hyperCKemia at rest (CK group) and in healthy athletes (control group). Prospective controlled study. Eighteen male Caucasian athletes with high serum CK levels at rest (CK between 80 and 150 U/L) and 25 male Caucasian athletes with normal serum CK levels at rest (CK between 10 and 80 U/L) Main Outcome Measures Blood samples were collected at rest, 30 minutes, 6 hours, 24 hours, 48 hours and 72 hours after a progressive cycloergometer test to exhaustion. The levels of serum CK and its isoenzymes were measured. In the control group, serum CK values at rest were normal (48.18 ± 14.14 U/L). After exercise, they increased slightly, though they always remained <80 U/L, decreasing to the rest level after 48 hours. The CK group had serum CK levels at rest higher than normal (116.56 ± 33.30 U/L). Serum CK levels were still outwith the normal range after 48 hours (130.11 ± 46.95 U/L) and 72 hours (116.55 ± 24.84 U/L). Serum CK levels were significantly different in both groups both before and after progressive cycloergometer test to exhaustion. In athletes with high serum CK levels at rest, serum CK levels remained elevated and had a different kinetics after exercise when compared with healthy athletes. PMID:23738242
Wintertime Air Pollution and the Greek Financial Crisis
NASA Astrophysics Data System (ADS)
Florou, Kalli K.; Pikridas, Michael; Pandis, Spyros N.
2013-04-01
During the last couple of years, because of the current high prices of diesel, Greeks have turned to more traditional ways of residential heating, such as fireplaces and pellet stoves. These combustion sources which use different types of biofuels, instead of fossil fuel or natural gas have become prevalent even in the major Greek cities. Wood combustion (WC) during winter is one of the major sources of organic aerosol in central and northern Europe (Puxbaum et al., 2007). Two field campaigns were conducted during the winter of 2012 and 2013 in two of the largest Greek cities (Patras and Athens) in order to quantify the levels of organic aerosols from domestic WC and to characterize the corresponding particulate matter. The instrumentation used included an Aerodyne High-Resolution Time-of-Flight Mass Spectrometer (HR-ToF-AMS) and a selection of on-line aerosol size distribution and concentration instruments (APS, SMPS, TEOM, MAAP) was deployed. In February of 2012, a significant increase of particulate matter less than 1 μm (PM1) was observed every evening after 6 pm in Patras (Pikridas et al., 2013). The concentration of PM1usually exceeded 80 μg m-3 often reaching values above 150 μg m-3. Organic particulate matter represented more than 90% of the fine PM during these high PM periods. The concentration of black carbon was as high as 10 μg m-3often exceeding the sulfate levels in the same area. High potassium and nitrate levels were also observed during the night. These concentrations were a lot higher (approximately double on average) than the concentrations measured in Patras during previous winters. In January 2013, these measurements were repeated both in Athens and Patras using a number of field stations. Wood burning once more resulted in extremely high nighttime PM levels. The spatial and temporal distribution of fine PM will be discussed and the effects of the change in heating fuels will be quantified. References Pikridas M., Tasoglou A., Florou K. and Pandis S. N. (2013) Characterization of the origin of fine particulate matter in a medium size urban area in the Mediterranean, Atmos. Environ., submitted. H. Puxbaum and Legrand, M., (2007), Summary of the CARBOSOL project: Present and retrospective state of organic versus inorganic aerosol over Europe, J. Geophys. Res., 112, D23S01, doi:10.1029/2006JD008271. Intergovernmental Panel on Climate Change (IPCC), Fourth Assessment Report: Summary for Policymakers, 2007.
The 3D Elevation Program: summary for Missouri
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Montana
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The new 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Louisiana
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Tennessee
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for New York
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
3D Elevation Program: summary for Vermont
Carswell, William J.
2015-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Maryland
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Ohio
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation's natural and constructed features.
The 3D Elevation Program: summary for Indiana
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation's natural and constructed features.
The 3D Elevation Program: summary for Maine
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Kentucky
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Oregon
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for North Dakota
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Florida
Carswell, William J.
2013-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The new 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the OMB Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
3D Elevation Program: summary for Nebraska
Carswell, William J.
2015-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Alabama
Carswell, William J.
2013-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The new 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A-16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
FWP executive summaries, Basic Energy Sciences Materials Sciences Programs (SNL/NM)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Samara, G.A.
1997-05-01
The BES Materials Sciences Program has the central theme of Scientifically Tailored Materials. The major objective of this program is to combine Sandia`s expertise and capabilities in the areas of solid state sciences, advanced atomic-level diagnostics and materials synthesis and processing science to produce new classes of tailored materials as well as to enhance the properties of existing materials for US energy applications and for critical defense needs. Current core research in this program includes the physics and chemistry of ceramics synthesis and processing, the use of energetic particles for the synthesis and study of materials, tailored surfaces and interfacesmore » for materials applications, chemical vapor deposition sciences, artificially-structured semiconductor materials science, advanced growth techniques for improved semiconductor structures, transport in unconventional solids, atomic-level science of interfacial adhesion, high-temperature superconductors, and the synthesis and processing of nano-size clusters for energy applications. In addition, the program includes the following three smaller efforts initiated in the past two years: (1) Wetting and Flow of Liquid Metals and Amorphous Ceramics at Solid Interfaces, (2) Field-Structured Anisotropic Composites, and (3) Composition-Modulated Semiconductor Structures for Photovoltaic and Optical Technologies. The latter is a joint effort with the National Renewable Energy Laboratory. Separate summaries are given of individual research areas.« less
Vaphiades, Michael S.; Kline, Lanning B.; McGwin, Gerald; Owsley, Cynthia; Shah, Ritu; Wood, Joanne M.
2014-01-01
Background. This study aimed to determine whether it is possible to predict driving safety of individuals with homonymous hemianopia or quadrantanopia based upon a clinical review of neuroimages that are routinely available in clinical practice. Methods. Two experienced neuroophthalmologists viewed a summary report of the CT/MRI scans of 16 participants with homonymous hemianopic or quadrantanopic field defects which indicated the site and extent of the lesion and they made predictions regarding whether participants would be safe/unsafe to drive. Driving safety was independently defined at the time of the study using state-recorded motor vehicle crashes (all crashes and at-fault) for the previous 5 years and ratings of driving safety determined through a standardized on-road driving assessment by a certified driving rehabilitation specialist. Results. The ability to predict driving safety was highly variable regardless of the driving safety measure, ranging from 31% to 63% (kappa levels ranged from −0.29 to 0.04). The level of agreement between the neuroophthalmologists was only fair (kappa = 0.28). Conclusions. Clinical evaluation of summary reports of currently available neuroimages by neuroophthalmologists is not predictive of driving safety. Future research should be directed at identifying and/or developing alternative tests or strategies to better enable clinicians to make these predictions. PMID:24683493
Vaphiades, Michael S; Kline, Lanning B; McGwin, Gerald; Owsley, Cynthia; Shah, Ritu; Wood, Joanne M
2014-01-01
Background. This study aimed to determine whether it is possible to predict driving safety of individuals with homonymous hemianopia or quadrantanopia based upon a clinical review of neuroimages that are routinely available in clinical practice. Methods. Two experienced neuroophthalmologists viewed a summary report of the CT/MRI scans of 16 participants with homonymous hemianopic or quadrantanopic field defects which indicated the site and extent of the lesion and they made predictions regarding whether participants would be safe/unsafe to drive. Driving safety was independently defined at the time of the study using state-recorded motor vehicle crashes (all crashes and at-fault) for the previous 5 years and ratings of driving safety determined through a standardized on-road driving assessment by a certified driving rehabilitation specialist. Results. The ability to predict driving safety was highly variable regardless of the driving safety measure, ranging from 31% to 63% (kappa levels ranged from -0.29 to 0.04). The level of agreement between the neuroophthalmologists was only fair (kappa = 0.28). Conclusions. Clinical evaluation of summary reports of currently available neuroimages by neuroophthalmologists is not predictive of driving safety. Future research should be directed at identifying and/or developing alternative tests or strategies to better enable clinicians to make these predictions.
Fast and accurate imputation of summary statistics enhances evidence of functional enrichment
Pasaniuc, Bogdan; Zaitlen, Noah; Shi, Huwenbo; Bhatia, Gaurav; Gusev, Alexander; Pickrell, Joseph; Hirschhorn, Joel; Strachan, David P.; Patterson, Nick; Price, Alkes L.
2014-01-01
Motivation: Imputation using external reference panels (e.g. 1000 Genomes) is a widely used approach for increasing power in genome-wide association studies and meta-analysis. Existing hidden Markov models (HMM)-based imputation approaches require individual-level genotypes. Here, we develop a new method for Gaussian imputation from summary association statistics, a type of data that is becoming widely available. Results: In simulations using 1000 Genomes (1000G) data, this method recovers 84% (54%) of the effective sample size for common (>5%) and low-frequency (1–5%) variants [increasing to 87% (60%) when summary linkage disequilibrium information is available from target samples] versus the gold standard of 89% (67%) for HMM-based imputation, which cannot be applied to summary statistics. Our approach accounts for the limited sample size of the reference panel, a crucial step to eliminate false-positive associations, and it is computationally very fast. As an empirical demonstration, we apply our method to seven case–control phenotypes from the Wellcome Trust Case Control Consortium (WTCCC) data and a study of height in the British 1958 birth cohort (1958BC). Gaussian imputation from summary statistics recovers 95% (105%) of the effective sample size (as quantified by the ratio of χ2 association statistics) compared with HMM-based imputation from individual-level genotypes at the 227 (176) published single nucleotide polymorphisms (SNPs) in the WTCCC (1958BC height) data. In addition, for publicly available summary statistics from large meta-analyses of four lipid traits, we publicly release imputed summary statistics at 1000G SNPs, which could not have been obtained using previously published methods, and demonstrate their accuracy by masking subsets of the data. We show that 1000G imputation using our approach increases the magnitude and statistical evidence of enrichment at genic versus non-genic loci for these traits, as compared with an analysis without 1000G imputation. Thus, imputation of summary statistics will be a valuable tool in future functional enrichment analyses. Availability and implementation: Publicly available software package available at http://bogdan.bioinformatics.ucla.edu/software/. Contact: bpasaniuc@mednet.ucla.edu or aprice@hsph.harvard.edu Supplementary information: Supplementary materials are available at Bioinformatics online. PMID:24990607
Van Straten, S; Stannard, C; Bulabula, J; Boodhia, K; Paul, K; Leong, J; Klipin, M J
2017-08-25
South Africa (SA) has an overburdened public healthcare system. Some patients admitted to Charlotte Maxeke Johannesburg Academic Hospital (CMJAH), SA, may not require tertiary care, but the numbers and details are uncertain. Clinical research in SA is limited by scarce skills and limited access to data. To determine the proportion of and length of stay for secondary-, tertiary- and quaternary-level patients discharged from the Department of Surgery at CMJAH over 1 year. This is a retrospective analysis of electronic discharge (ED) summaries from the Department of Surgery at CMJAH between 1 April 2015 and 1 April 2016. An SQL query of the database generated a .csv file of all discharges with the following fields: database reference number, length of stay and level of care. The details of each record were verified by MBBCh V students, using a defined level-ofcare template and the full discharge summary. The data were reviewed by a senior clinician. There were 3 007 discharge summaries - 97 were not classifiable, two were test records and one was a duplicate. These 100 records were excluded. There were no primary-level records. Secondary-level patients represented 29% (854) of those discharged and 19% of total bed days. Tertiary- and quaternary-level patients together represented 71% of the total and 81% of bed days. The average length of stay was 4.31 days for secondary, 6.98 days for tertiary and 9.77 days for quaternary level-of-care allocation. Almost one-third (29%) of patients discharged from CMJAH's Department of Surgery were deemed suitable for secondarylevel care. These patients had a shorter length of stay and comprised 19% of total bed days. Students and electronic databases represent an important research resource.
Alternate space shuttle concepts study. Part 2: Technical summary. Volume 2: Orbiter definition
NASA Technical Reports Server (NTRS)
1971-01-01
A study was conducted of a three-engined external hydrogen tank orbiter/heat sink booster utilizing 415 K sea level thrust engines. The results of the study, pertaining to the orbiter portion of the configuration, are presented. A complete summary of characteristics is given for the external tank configuration along with some comparative data for a conventional internal tank configuration.
Power conditioning for space nuclear reactor systems
NASA Technical Reports Server (NTRS)
Berman, Baruch
1987-01-01
This paper addresses the power conditioning subsystem for both Stirling and Brayton conversion of space nuclear reactor systems. Included are the requirements summary, trade results related to subsystem implementation, subsystem description, voltage level versus weight, efficiency and operational integrity, components selection, and shielding considerations. The discussion is supported by pertinent circuit and block diagrams. Summary conclusions and recommendations derived from the above studies are included.
Meuwese, Christiaan L.; Dekker, Friedo W.; Lindholm, Bengt; Qureshi, Abdul R.; Heimburger, Olof; Barany, Peter; Stenvinkel, Peter; Carrero, Juan J.
2012-01-01
Summary Background and objectives Conflicting evidence exists with regard to the association of thyroid hormones and mortality in dialysis patients. This study assesses the association between basal and trimestral variation of thyroid stimulating hormone, triiodothyronine, and thyroxine and mortality. Design, setting, participants, & measurements In 210 prevalent hemodialysis patients, serum triiodothyronine, thyroxine, thyroid stimulating hormone, and interleukin-6 were measured 3 months apart. Cardiovascular and non-cardiovascular deaths were registered during follow-up. Based on fluctuations along tertiles of distribution, four trimestral patterns were defined for each thyroid hormone: persistently low, decrease, increase, and persistently high. The association of baseline levels and trimestral variation with mortality was investigated with Kaplan–Meier curves and Cox proportional hazard models. Results During follow-up, 103 deaths occurred. Thyroid stimulating hormone levels did not associate with mortality. Patients with relatively low basal triiodothyronine concentrations had higher hazards of dying than patients with high levels. Longitudinally, patients with persistently low levels of triiodothyronine during the 3-month period had higher mortality hazards than those having persistently high levels. These associations were mainly attributable to cardiovascular-related mortality. The association between thyroxine and mortality was not altered after adjustment for triiodothyronine. Conclusions Hemodialysis patients with reduced triiodothyronine or thyroxine levels bear an increased mortality risk, especially due to cardiovascular causes. This was true when considering both baseline measurements and trimestral variation patterns. Our longitudinal design adds observational evidence supporting the hypothesis that the link may underlie a causal effect. PMID:22246282
Xavier-Magalhães, Ana; Gonçalves, Céline S.; Fogli, Anne; Lourenço, Tatiana; Pojo, Marta; Pereira, Bruno; Rocha, Miguel; Lopes, Maria Celeste; Crespo, Inês; Rebelo, Olinda; Tão, Herminio; Lima, João; Moreira, Ricardo; Pinto, Afonso A.; Jones, Chris; Reis, Rui M.; Costello, Joseph F.; Arnaud, Philippe; Sousa, Nuno; Costa, Bruno M.
2018-01-01
The lncRNA HOTAIR has been implicated in several human cancers. Here, we evaluated the molecular alterations and upstream regulatory mechanisms of HOTAIR in glioma, the most common primary brain tumors, and its clinical relevance. HOTAIR gene expression, methylation, copy-number and prognostic value were investigated in human gliomas integrating data from online datasets and our cohorts. High levels of HOTAIR were associated with higher grades of glioma, particularly IDH wild-type cases. Mechanistically, HOTAIR was overexpressed in a gene dosage-independent manner, while DNA methylation levels of particular CpGs in HOTAIR locus were associated with HOTAIR expression levels in GBM clinical specimens and cell lines. Concordantly, the demethylating agent 5-Aza-2′-deoxycytidine affected HOTAIR transcriptional levels in a cell line-dependent manner. Importantly, HOTAIR was frequently co-expressed with HOXA9 in high-grade gliomas from TCGA, Oncomine, and our Portuguese and French datasets. Integrated in silico analyses, chromatin immunoprecipitation, and qPCR data showed that HOXA9 binds directly to the promoter of HOTAIR. Clinically, GBM patients with high HOTAIR expression had a significantly reduced overall survival, independently of other prognostic variables. In summary, this work reveals HOXA9 as a novel direct regulator of HOTAIR, and establishes HOTAIR as an independent prognostic marker, providing new therapeutic opportunities to treat this highly aggressive cancer. PMID:29644006
Kirtane, Ameya R; Rothenberger, Meghan K; Frieberg, Abby; Nephew, Karla; Schultz-Darken, Nancy; Schmidt, Thomas; Reimann, Thomas; Haase, Ashley T; Panyam, Jayanth
2017-07-01
The human immunodeficiency virus epidemic affects millions of people worldwide. As women are more vulnerable to infection, female-controlled interventions can help control the spread of the disease significantly. Glycerol monolaurate (GML), an inexpensive and safe compound, has been shown to protect against simian immunodeficiency virus infection when applied vaginally. However, on account of its low aqueous solubility, fabrication of high-dose formulations of GML has proven difficult. We describe the development of a vaginal cream that could be loaded with up to 35% GML. Vaginal drug levels and safety of 3 formulations containing increasing concentrations of GML (5%w/w, 15%w/w, and 35%w/w) were tested in rhesus macaques after vaginal administration. GML concentration in the vaginal tissue increased as the drug concentration in the cream increased, with 35% GML cream resulting in tissue concentration of ∼0.5 mg/g, albeit with high interindividual variability. Compared with the vehicle control, none of the GML creams had any significant effect on the vaginal flora and cytokine (macrophage inflammatory protein 3α and interleukin 8) levels, suggesting that high-dose GML formulations do not induce local adverse effects. In summary, we describe the development of a highly loaded vaginal cream of GML, and vaginal drug levels and safety after local administration in macaques. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.
Smith, Adam M; Smith, Martyn T; La Merrill, Michele A; Liaw, Jane; Steinmaus, Craig
2017-04-01
2,4-Dichlorophenoxyacetic acid (2,4-D) is one of the most commonly used selective herbicides in the world. A number of epidemiology studies have found an association between 2,4-D exposure and non-Hodgkin lymphoma (NHL) but these results are inconsistent and controversial. A previous meta-analysis found no clear association overall but did not specifically examine high-exposure groups. We conducted a systematic review and meta-analysis of the peer-reviewed epidemiologic studies of the associations between 2,4-D and NHL, with a particular focus on high-exposure groups, and evaluations of heterogeneity, dose-response, and bias. A total of 12 observational studies, 11 case-control studies, and one cohort study, were included. The summary relative risk for NHL using study results comparing subjects who were ever versus never exposed to 2,4-D was 1.38 (95% confidence interval (CI), 1.07-1.77). However, in analyses focusing on results from highly exposed groups, the summary relative risk for NHL was 1.73 (95% CI, 1.10-2.72). No clear bias based on study design, exposure assessment methodology, or outcome misclassification was seen. Overall, these findings provide new evidence for an association between NHL and exposure to the herbicide 2,4-D. Copyright © 2017 Elsevier Inc. All rights reserved.
Remote-handled/special case TRU waste characterization summary
DOE Office of Scientific and Technical Information (OSTI.GOV)
Detamore, J.A.
1984-03-30
TRU wastes are those (other than high level waste) contaminated with specified quantities of certain alpha-emitting radionuclides of long half-life and high specific radiotoxicity. TRU waste is defined as /sup 226/Ra isotopic sources and those other materials that, without regard to source or form, are contaminated with transuranic elements with half-lives greater than 20 years, and have TRU alpha contamination greater than 100 nCi/g. RH TRU waste has high beta and gamma radiation levels, up to 30,000 R/hr, and thermal output may be a few hundred watts per container. The radiation levels in most of this remotely handled (RH) TRUmore » waste, however, are below 100 R/hr. Remote-handled wastes are stored at Los Alamos, Hanford, Oak Ridge, and the Idaho National Engineering Laboratory. This report presents a site by site discussion of RH waste handling, placement, and container data. This is followed by a series of data tables that were compiled in the TRU Waste Systems Office. These tables are a compendium of data that are the most up to date and accurate data available today. 10 tables.« less
Tani, Masaji; Kawai, Manabu; Okada, Ken-Ichi; Hirono, Seiko; Hotta, Tsukasa; Takifuji, Katsunari; Yamaue, Hiroki
2015-05-01
Laparoscopic cholecystectomy (LC) has become the standard procedure, and contributes to a shorter hospital stay. However, there have been no reports regarding when the patients can be discharged in terms of their health-related quality of life (HRQOL). The HRQOL was evaluated by using the SF-8 health survey (SF-8) 24-hour version in 127 consecutive patients treated from May 2007 to December 2008. The HRQOL and a visual analogue scale (VAS) score were assessed on the day before surgery and on postoperative day (POD) 1, POD2 and POD7. All scores of the eight domains on POD1 were significantly decreased compared to the preoperative score (P < 0.05), and seven scores were still decreased on POD2, with the mental health (MH) domain showing an improvement. On POD7, the general health score improved to the preoperative level. The physical component summary 8 (PCS-8) was suppressed for all 7 days after LC. The mental health component summary 8 (MCS-8) was improved to the preoperative level on POD2, despite the significant suppression observed on POD1 (P < 0.05). The VAS score was higher in the low PCS-8 (PCS-8 < 42.4) and low MCS-8 (MCS-8 < 40.6) patients than in the high PCS-8 and high MCS-8 patients. The HRQOL score demonstrated the improvement of the MCS-8 on POD2, which might suggest that a discharge of LC patients is appropriate on POD2 in terms of the patients' point of view.
Murphy, S F; Lenihan, L; Orefuwa, F; Colohan, G; Hynes, I; Collins, C G
2017-05-01
The discharge letter is a key component of the communication pathway between the hospital and primary care. Accuracy and timeliness of delivery are crucial to ensure continuity of patient care. Electronic discharge summaries (EDS) and prescriptions have been shown to improve quality of discharge information for general practitioners (GPs). The aim of this study was to evaluate the effect of a new EDS on GP satisfaction levels and accuracy of discharge diagnosis. A GP survey was carried out whereby semi-structured interviews were conducted with 13 GPs from three primary care centres who receive a high volume of discharge letters from the hospital. A chart review was carried out on 90 charts to compare accuracy of ICD-10 coding of Non-Consultant Hospital Doctors (NCHDs) with that of trained Hopital In-Patient Enquiry (HIPE) coders. GP satisfaction levels were over 90 % with most aspects of the EDS, including amount of information (97 %), accuracy (95 %), GP information and follow-up (97 %) and medications (91 %). 70 % of GPs received the EDS within 2 weeks. ICD-10 coding of discharge diagnosis by NCHDs had an accuracy of 33 %, compared with 95.6 % when done by trained coders (p < 0.00001). The introduction of the EDS and prescription has led to improved quality of timeliness of communication with primary care. It has led to a very high satisfaction rating with GPs. ICD-10 coding was found to be grossly inaccurate when carried out by NCHDs and it is more appropriate for this task to be carried out by trained coders.
Increased Lung Volume in Infants and Toddlers at High Compared to Low Altitude
Llapur, Conrado J.; Martínez, Myriam R.; Caram, María Marta; Bonilla, Federico; Cabana, Celia; Yu, Zhansheng; Tepper, Robert S.
2015-01-01
Summary Children and adults residing at high altitude (HA) compared to low altitude (LA) have larger lung volumes; however, it is unknown whether this response to chronic hypoxia begins early in life. Our objective was to determine whether infants and toddlers at HA have larger lung volumes compared to infants and toddlers at LA. Oxygen saturation (SaO2), functional residual capacity (FRC), as well as serum levels of vascular endothelial growth factor (VEGF) and erythropoietin (EPO) were measured in infants and toddlers from HA (N = 50; 3,440 m) and LA (N = 35; 440 m). There were no significant differences in somatic size for HA and LA subjects; however, HA subjects had significantly lower SaO2 (88.5% vs. 96.7%; P < 0.0001). Subjects at HA had significantly greater FRC compared to subjects at LA (group mean: 209 and 157 ml; P < 0.0001), adjusting for body length. Male infants at HA had a significantly greater FRC compared to males at LA (57 ml; P-value < 0.001); however, the increase in FRC for females at HA compared to LA was not significant (20 ml; P-value = 0.101). VEGF and EPO were significantly higher for subjects at HA compared to LA with no gender differences. In summary, infants and toddlers at HA have lower oxygen saturations, higher serum levels of VEGF and EPO, and higher FRC compared to subjects at LA; however, chronic hypoxia appears to generate a more robust response in lung growth in male compared to female infants early in life. PMID:23401418
78 FR 59985 - Variable Insurance Trust, et al.;
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-30
... Trust, et al.; Notice of Application September 24, 2013. AGENCY: Securities and Exchange Commission... Trust (the ``Fund'') and MFund Services LLC (``MFund'') (collectively, ``Applicants''). SUMMARY: Summary... Services LLC, 22 High Street, Huntington, NY 11743 and Jerry Szilagyi, Variable Insurance Trust, 5...
English, René; Peer, Nazia; Honikman, Simone; Tugendhaft, Aviva; Hofman, Karen J
2017-01-01
In South Africa (SA), despite adoption of international strategies and approaches, maternal, neonatal and child (MNC) morbidity and mortality rates have not sufficiently declined. To conduct an umbrella review (UR) that identifies interventions in low- and middle-income countries, with a high-quality evidence base, that improve MNC morbidity and mortality outcomes within the first 1000 days of life; and to assess the incorporation of the evidence into local strategies, guidelines and documents. We included publications about women and children in the first 1000 days of life; healthcare professionals and community members. Comparators were those who did not receive the intervention. Interventions were pharmacological and non-pharmacological. Outcomes were MNC morbidity and mortality. Authors conducted English language electronic and manual searches (2000-2013). The quality of systematic reviews and meta-analyses (SRs/MAs) were reviewed. Interventions were ranked according to level of evidence; and then aligned with SA strategies, policies and guidelines. A tool to extract data was developed and used by two authors who independently extracted data. Summary measures from MAs or summaries of SRs were reviewed and the specificities of the various interventions listed. A search of all local high-level documents was done and these were assessed to determine the specificities of the recommendations and their alignment to the evidence. In total, 19 interventions presented in 32 SRs were identified. Overall, SA's policymakers have sufficiently included high-quality evidence-based interventions into local policies. However, optimal period of birth spacing (two to five years) is not explicitly promoted nor was ante- and postnatal depression adequately incorporated. Antenatal care visits should be increased from four to about eight according to the evidence. Incorporation of existing evidence into policies can be strengthened in SA. The UR methods are useful to inform policymaking and identify research gaps. RESPONSIBLE EDITOR Nawi Ng, Umeå University, Sweden.
English, René; Peer, Nazia; Honikman, Simone; Tugendhaft, Aviva; Hofman, Karen J
2017-01-01
ABSTRACT Background: In South Africa (SA), despite adoption of international strategies and approaches, maternal, neonatal and child (MNC) morbidity and mortality rates have not sufficiently declined. Objectives: To conduct an umbrella review (UR) that identifies interventions in low- and middle-income countries, with a high-quality evidence base, that improve MNC morbidity and mortality outcomes within the first 1000 days of life; and to assess the incorporation of the evidence into local strategies, guidelines and documents. Methods: We included publications about women and children in the first 1000 days of life; healthcare professionals and community members. Comparators were those who did not receive the intervention. Interventions were pharmacological and non-pharmacological. Outcomes were MNC morbidity and mortality. Authors conducted English language electronic and manual searches (2000–2013). The quality of systematic reviews and meta-analyses (SRs/MAs) were reviewed. Interventions were ranked according to level of evidence; and then aligned with SA strategies, policies and guidelines. A tool to extract data was developed and used by two authors who independently extracted data. Summary measures from MAs or summaries of SRs were reviewed and the specificities of the various interventions listed. A search of all local high-level documents was done and these were assessed to determine the specificities of the recommendations and their alignment to the evidence. Results: In total, 19 interventions presented in 32 SRs were identified. Overall, SA’s policymakers have sufficiently included high-quality evidence-based interventions into local policies. However, optimal period of birth spacing (two to five years) is not explicitly promoted nor was ante- and postnatal depression adequately incorporated. Antenatal care visits should be increased from four to about eight according to the evidence. Conclusion: Incorporation of existing evidence into policies can be strengthened in SA. The UR methods are useful to inform policymaking and identify research gaps. RESPONSIBLE EDITOR Nawi Ng, Umeå University, Sweden PMID:28715934
Martin, Petra; Biniecka, Monika; Ó'Meachair, Shane; Maguire, Aoife; Tosetto, Miriam; Nolan, Blathnaid; Hyland, John; Sheahan, Kieran; O'Donoghue, Diarmuid; Mulcahy, Hugh; Fennelly, David; O'Sullivan, Jacintha
2018-01-01
Despite treatment of patients with metastatic colorectal cancer (mCRC) with bevacizumab plus chemotherapy, response rates are modest and there are no biomarkers available that will predict response. The aim of this study was to assess if markers associated with three interconnected cancer-associated biological processes, specifically angiogenesis, inflammation and oxidative damage, could stratify the survival outcome of this cohort. Levels of angiogenesis, inflammation and oxidative damage markers were assessed in pre-bevacizumab resected tumour and serum samples of mCRC patients by dual immunofluorescence, immunohistochemistry and ELISA. This study identified that specific markers of angiogenesis, inflammation and oxidative damage stratify survival of patients on this anti-angiogenic treatment. Biomarkers of immature tumour vasculature (% IMM, p=0.026, n=80), high levels of oxidative damage in the tumour epithelium (intensity of 8-oxo-dG in nuclear and cytoplasmic compartments, p=0.042 and 0.038 respectively, n=75) and lower systemic pro-inflammatory cytokines (IL6 and IL8, p=0.053 and 0.049 respectively, n=61) significantly stratify with median overall survival (OS). In summary, screening for a panel of biomarkers for high levels of immature tumour vasculature, high levels of oxidative DNA damage and low levels of systemic pro-inflammatory cytokines may be beneficial in predicting enhanced survival outcome following bevacizumab treatment for mCRC. PMID:29535825
Karppinen, Jaro; Leino-Arjas, Päivi; Solovieva, Svetlana; Varonen, Helena; Kalso, Eija; Ukkola, Olavi; Viikari-Juntura, Eira
2007-01-01
Lumbar radicular pain is a fairly common health problem, yet its risk factors are far from clear. There are no published systematic reviews on associations between cardiovascular or lifestyle risk factors and lumbar radicular pain or sciatica. The aim of this systematic literature review was to assess associations between these risk factors and lumbar radicular pain or sciatica. We conducted a systematic search of the Medline database for all original articles on lumbar radicular pain or sciatica published until August 2006. Twenty-two papers from 19 studies were included in the review. Overweight or obesity was associated with sciatica in most of the case-control and cohort studies. Some studies showed an increased risk of lumbar radicular pain in smokers with a long smoking history or in those with high levels of physical activity. A few case-control studies showed an association between serum C-reactive protein and sciatica. No consistent associations were found for serum lipids levels or high blood pressure. In summary, the associations of overweight, long smoking history, high physical activity and a high serum C-reactive protein level with lumbar radicular pain or sciatica were substantiated by the present review. However, more prospective studies are needed in order to further clarify these associations and the mechanisms of action. PMID:17525856
Multiple Phenotype Association Tests Using Summary Statistics in Genome-Wide Association Studies
Liu, Zhonghua; Lin, Xihong
2017-01-01
Summary We study in this paper jointly testing the associations of a genetic variant with correlated multiple phenotypes using the summary statistics of individual phenotype analysis from Genome-Wide Association Studies (GWASs). We estimated the between-phenotype correlation matrix using the summary statistics of individual phenotype GWAS analyses, and developed genetic association tests for multiple phenotypes by accounting for between-phenotype correlation without the need to access individual-level data. Since genetic variants often affect multiple phenotypes differently across the genome and the between-phenotype correlation can be arbitrary, we proposed robust and powerful multiple phenotype testing procedures by jointly testing a common mean and a variance component in linear mixed models for summary statistics. We computed the p-values of the proposed tests analytically. This computational advantage makes our methods practically appealing in large-scale GWASs. We performed simulation studies to show that the proposed tests maintained correct type I error rates, and to compare their powers in various settings with the existing methods. We applied the proposed tests to a GWAS Global Lipids Genetics Consortium summary statistics data set and identified additional genetic variants that were missed by the original single-trait analysis. PMID:28653391
Annual Summary of the Integrated Disposal Facility Performance Assessment 2011
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lehman, L. L.
2012-03-12
An annual summary of the adequacy of the Hanford Immobilized Low-Activity Waste (ILAW) Performance Assessment (PA) is required each year (DOE O 435.1 Chg 1,1 DOE M 435.1-1 Chg 1,2 DOE/ORP-2000-013). The most recently approved PA is DOE/ORP-2000-24.4 The ILAW PA evaluated the adequacy of the ILAW disposal facility, now referred to as the Integrated Disposal Facility (IDF), for the safe disposal of vitrified Hanford Site tank waste. More recently, a preliminary evaluation for the disposal of offsite low-level waste and mixed low-level waste was considered in RPP-1583.
Singh, Harminder; Kaur, Kamalpreet; Dulhani, Navin; Bansal, Akash; Kumar, Bithika N.; Chouhan, Vinod Kumar Singh
2013-01-01
Background: Highly active antiretroviral therapy regimens have resulted in the systemic/clinical healing for human immune deficiency virus-infected patients but the consequence of antiretroviral therapy on the whole quality of life has become a major concern. The current study correlates the relationship of quality of life with successful highly active antiretroviral therapy. Aim: To determine the health-related quality of life in human immune deficiency virus-infected patients on highly active anti-retroviral therapy regimen in tribal region of Chhattisgarh. Design: An open label prospective study. Materials and Methods: Health-related quality of life was assessed using a standardized questionnaire, the Medical Outcomes Survey Short Form 36. Physical health summary scores and mental health summary scores were compared of pre-Highly Active Anti-Retroviral Therapy (at baseline) and post 12 months of therapy. Results: The increase in CD4 cell counts was extremely significant (P < 0.0001). The Physical Composite Summary (P value = 0.0003) improved significantly, whereas the Mental Composite Summary (with a baseline value of 40.7), post 12 months, was calculated as 42.8 (P value = 0.2371) and was statistically not significant. Conclusion: Efficacy measurement is the key ingredient of highly active anti-retroviral therapy, which must also include assessment of health-related quality of life to maximize the holistic approach towards disease. PMID:24049364
Data Release Summary Statement
Atmospheric Science Data Center
2016-11-14
... of the CALIPSO data products includes new versions of its standard Level1 and Level2 lidar data. The V4.10 CALIOP Level 2 data products ... essential ancillary data sets. The GTOPO30 Digital Elevation Model (DEM) used in V4.00 has been replaced by a substantially more accurate ...
Environmental Management Performance Report June 2000
DOE Office of Scientific and Technical Information (OSTI.GOV)
EDER, D.M.
2000-06-01
The purpose of this report is to provide the Department of Energy Richland Operations Office (DOE-RL) a monthly summary of the Project Hanford Management Contractor's (PHMC) Environmental Management (EM) performance by Fluor Hanford (FH) and its subcontractors. In addition to project-specific information, it includes some PHMC-level data not detailed elsewhere in the report. Section A, Executive Summary, provides an executive level summary of the cost, schedule, and technical performance described in this report. It summarizes performance for the period covered, highlights areas worthy of management attention, and provides a forward look to some of the upcoming key performance activities asmore » extracted from the PHMC baseline. The remaining sections provide detailed performance data relative to each individual Project (e.g., Waste Management, Spent Nuclear Fuels, etc.), in support of Section A of the report. Unless otherwise noted, the Safety, Conduct of Operations, and Cost/Schedule data contained herein is as of April 30, 2000. All other information is updated as of May 19, unless otherwise noted.« less
Level of Service Program for INDOT Operations : [Technical Summary
DOT National Transportation Integrated Search
2012-01-01
In 2008 the JTRP study SPR-3130, Performance Based : Contracting for Roadway Maintenance Operations, : revealed the state agencies that have developed a : Level of Service (LOS) program benefit. A LOS program : can evaluate and determine maintenance ...
Petkovic, Jennifer; Welch, Vivian; Tugwell, Peter
2015-09-28
Systematic reviews are important for decision-makers. They offer many potential benefits but are often written in technical language, are too long, and do not contain contextual details which makes them hard to use for decision-making. There are many organizations that develop and disseminate derivative products, such as evidence summaries, from systematic reviews for different populations or subsets of decision-makers. This systematic review will assess the effectiveness of systematic review summaries on increasing policymakers' use of systematic review evidence and to identify the components or features of these summaries that are most effective. We will include studies of policy-makers at all levels as well as health-system managers. We will include studies examining any type of "evidence summary," "policy brief," or other products derived from systematic reviews that present evidence in a summarized form. The primary outcomes are the following: (1) use of systematic review summaries decision-making (e.g., self-reported use of the evidence in policy-making, decision-making) and (2) policy-maker understanding, knowledge, and/or beliefs (e.g., changes in knowledge scores about the topic included in the summary). We will conduct a systematic review of randomized controlled trials (RCTs), non-randomized controlled trials (NRCTs), controlled before-after studies (CBA), and interrupted time series (ITS) studies. The results of this review will inform the development of future systematic review summaries to ensure that systematic review evidence is accessible to and used by policy-makers making health-related decisions.
Xu, Huanbin; Wang, Xiaolei; Lackner, Andrew A; Veazey, Ronald S
2014-01-01
CD4+ T follicular helper (TFH) cells guide development and maturation of B cells and are crucial for effective antibody responses. Here we found rhesus macaque TFH cells, defined as CXCR5+CD4 T cells, contain two major populations: PD-1(INT) and PD-1(HIGH) cells. Of these, PD-1(HIGH)CD4+ T cells highly co-express ICOS but little CCR7, and reside in lymph node germinal centers (GCs), but not in blood. These cells secrete IL-21 and express transcriptional factor Bcl-6 at higher levels than CXCR5+PD-1(INT)CD4+ T cells. In addition, the frequency of PD-1(HIGH)CD4+ T cells is low in lymph nodes of newborns, but increases with age. Levels of PD-1(HIGH)CD4+ T cells correlate with mature B cells in lymph nodes, and PD-1 blockade in PD-1(HIGH)CD4+ T and B cell co-cultures significantly inhibits IgG production. In summary, PD-1(HIGH)CD4+ T cells residing in GC represent a specific TFH subset that contributes to maturation of B cells and IgG production.
Adaptive harvest management for the Svalbard population of pink-footed geese: briefing summary
Johnson, Fred A.
2013-01-01
The African-Eurasian Waterbird Agreement (AEWA; http://www.unep-aewa.org/) calls for means to manage populations which cause conflicts with certain human economic activities. The Svalbard population of the pink-footed goose has been selected as the first test case for such an international species management plan to be developed. This document describes progress to date on the development of an adaptive harvest management (AHM) strategy for maintaining pink-footed goose abundance near their target level by providing for sustainable harvasts in Norway and Denmark. This briefing supplements material provided in the Progress Summary distributed to the International Working Group on February 1, 2013. We emphasize that peer review is an essential aspect of the process of developing and implementing an AHM program for pink-footed geese, and we will continue to solicit reviews by the International Working Group and their staff, as well as scientists not engaged in this effort. We wish to make the Working Group aware the the following two manuscripts have been submitted recently to refereed journals and are available upon request from the senior authors: Jensen, G.H., J. Madsen, F.A. Johnson, and M. Tamstorf. Snow conditions as an estimator of the breeding output in high-Arctic pink-footed geese Anser brachyrhynchus. Polar Biology: In review. Johnson, F.A., G.H. Jensen, J. Madsen, and B.K. Williams. Uncertainity, robustness, and the value of information in managing an expanding Arctic goose population. Ecological Modeling: In review. In addition to these manuscripts, the Progress Summary (February 1, 2013), and this Briefing Summary (April 23, 2013) an annual report will be produced in August 2013 and every summer thereafter. Additional manuscripts for journal publication are also anticipated.
Arnold, Melina; Rentería, Elisenda; Conway, David I; Bray, Freddie; Van Ourti, Tom; Soerjomataram, Isabelle
2016-08-01
Inequalities in the burden of cancer have been well documented, and a variety of measures exist to analyse disease disparities. While previous studies have focused on inequalities within countries, the aim of the present study was to quantify existing inequalities in cancer incidence and mortality between countries. Data on total and site-specific cancer incidence and mortality in 2003-2007 were obtained for 43 countries with medium-to-high levels of human development via Cancer Incidence in Five Continents Vol. X and the WHO Mortality Database. We calculated the concentration index as a summary measure of socioeconomic-related inequality between countries. Inequalities in cancer burden differed markedly by site; the concentration index for all sites combined was 0.03 for incidence and 0.02 for mortality, pointing towards a slightly higher burden in countries with higher levels of the human development index (HDI). For both incidence and mortality, this pattern was most pronounced for melanoma. In contrast, the burden of cervical cancer was disproportionally high in countries with lower HDI levels. Prostate, lung and breast cancer contributed most to inequalities in overall cancer incidence in countries with higher HDI levels, while for mortality these were mostly driven by lung cancer in higher HDI countries and stomach cancer in countries with lower HDI levels. Global inequalities in the burden of cancer remain evident at the beginning of the twenty-first century: with a disproportionate burden of lifestyle-related cancers in countries classified as high HDI, while infection-related cancers continue to predominate in transitioning countries with lower levels of HDI.
Werner, Rachel M; Konetzka, R Tamara; Polsky, Daniel
2016-06-01
Limited consumer use of health care report cards may be due to the large amount of information presented in report cards, which can be difficult to understand. These limitations may be overcome with summary measures. Our objective was to evaluate consumer response to summary measures in the setting of nursing homes. 2005-2010 nursing home Minimum Data Set and Online Survey, Certification and Reporting (OSCAR) datasets. In December 2008, Medicare converted its nursing home report card to summary or star ratings. We test whether there was a change in consumer demand for nursing homes related to the nursing home's star rating after the information was released. The star rating system was associated with a significant change in consumer demand for low- and high-scoring facilities. After the star-based rating system was released, 1-star facilities typically lost 8 percent of their market share and 5-star facilities gained over 6 percent of their market share. The nursing home star rating system significantly affected consumer demand for high- and low-rated nursing homes. These results support the use of summary measures in report cards. © Health Research and Educational Trust.
ERIC Educational Resources Information Center
Christophersen, Kjell A.; Robison, M. Henry
This document contains an executive summary, main report, and detailed results by entry level of education, gender and ethnicity. The ways in which the State of Mississippi economy benefits from the presence of the 15 community college districts in the state are examined. The Mississippi community colleges employed 4,940 full- and part-time…
ERIC Educational Resources Information Center
Christophersen, Kjell A.; Robison, M. Henry
This document contains an executive summary, main report, and detailed results by entry level of education, gender and ethnicity. The report examines the ways in which the State of Maryland economy benefits from the presence of the 16 community college districts in the state. Volume 1 is the Main Report, and Volume 2 includes detailed results. The…
Fighter pilots' heart rate, heart rate variation and performance during instrument approaches.
Mansikka, Heikki; Simola, Petteri; Virtanen, Kai; Harris, Don; Oksama, Lauri
2016-10-01
Fighter pilots' heart rate (HR), heart rate variation (HRV) and performance during instrument approaches were examined. The subjects were required to fly instrument approaches in a high-fidelity simulator under various levels of task demand. The task demand was manipulated by increasing the load on the subjects by reducing the range at which they commenced the approach. HR and the time domain components of HRV were used as measures of pilot mental workload (PMWL). The findings of this study indicate that HR and HRV are sensitive to varying task demands. HR and HRV were able to distinguish the level of PMWL after which the subjects were no longer able to cope with the increasing task demands and their instrument landing system performance fell to a sub-standard level. The major finding was the HR/HRV's ability to differentiate the sub-standard performance approaches from the high-performance approaches. Practitioner Summary: This paper examined if HR and HRV were sensitive to varying task demands in a fighter aviation environment and if these measures were related to variations in pilot's performance.
A BEHAVIORAL ECONOMIC MODEL OF ALCOHOL ADVERTISING AND PRICE
SAFFER, HENRY; DAVE, DHAVAL; GROSSMAN, MICHAEL
2016-01-01
SUMMARY This paper presents a new empirical study of the effects of televised alcohol advertising and alcohol price on alcohol consumption. A novel feature of this study is that the empirical work is guided by insights from behavioral economic theory. Unlike the theory used in most prior studies, this theory predicts that restriction on alcohol advertising on TV would be more effective in reducing consumption for individuals with high consumption levels but less effective for individuals with low consumption levels. The estimation work employs data from the National Longitudinal Survey of Youth, and the empirical model is estimated with quantile regressions. The results show that advertising has a small positive effect on consumption and that this effect is relatively larger at high consumption levels. The continuing importance of alcohol taxes is also supported. Education is employed as a proxy for self-regulation, and the results are consistent with this assumption. The key conclusion is that restrictions on alcohol advertising on TV would have a small negative effect on drinking, and this effect would be larger for heavy drinkers. PMID:25919364
Potential Collaborative Research topics with Korea’s Agency for Defense Development
DOE Office of Scientific and Technical Information (OSTI.GOV)
Farrar, Charles R.; Todd, Michael D.
2012-08-23
This presentation provides a high level summary of current research activities at the Los Alamos National Laboratory (LANL)-University of California Jacobs School of Engineering (UCSD) Engineering Institute that will be presented at Korea's Agency for Defense Development (ADD). These research activities are at the basic engineering science level with different level of maturity ranging from initial concepts to field proof-of-concept demonstrations. We believe that all of these activities are appropriate for collaborative research activities with ADD subject to approval by each institution. All the activities summarized herein have the common theme that they are multi-disciplinary in nature and typically involvedmore » the integration of high-fidelity predictive modeling, advanced sensing technologies and new development in information technology. These activities include: Wireless Sensor Systems, Swarming Robot sensor systems, Advanced signal processing (compressed sensing) and pattern recognition, Model Verification and Validation, Optimal/robust sensor system design, Haptic systems for large-scale data processing, Cyber-physical security for robots, Multi-source energy harvesting, Reliability-based approaches to damage prognosis, SHMTools software development, and Cyber-physical systems advanced study institute.« less
Jones, David R; Pike, Katie; Kenyon, Sara; Pike, Laura; Henderson, Brian; Brocklehurst, Peter; Marlow, Neil; Salt, Alison; Taylor, David J
2011-01-01
Statutory educational attainment measures are rarely used as health study outcomes, but Key Stage 1 (KS1) data formed secondary outcomes in the long-term follow-up to age 7 years of the ORACLE II trial of antibiotic use in preterm babies. This paper describes the approach, compares different approaches to analysis of the KS1 data and compares use of summary KS1 (level) data with use of individual question scores. 3394 children born to women in the ORACLE Children Study and resident in England at age 7. Analysis of educational achievement measured by national end of KS1 data (KS1) using Poisson regression modelling and anchoring of the KS1 data using external standards. KS1 summary level data were obtained for 3239 (95%) eligible children; raw individual question scores were obtained for 1899 (54%). Use of individual question scores where available did not change the conclusion of no evidence of treatment effects based on summary KS1 outcome data. When accessible for medical research purposes, routinely collected educational outcome data may have advantages of low cost and standardised definition. Here, summary scores lead to similar conclusions to raw (individual question) scores and so are attractive and cost-effective alternatives.
Glymour, M. Maria; Weuve, Jennifer; Fay, Martha E.; Glass, Thomas; Berkman, Lisa F.
2008-01-01
Background/Aims Little is known about the possible effects of social resources on stroke survivors’ level and change in cognitive outcomes. Understanding this association may help us identify strategies to improve stroke recovery and help elucidate the etiology of dementia. Methods We examined the relationship of social ties and social support to cognitive function and cognitive change 6 months after stroke. Participants in the Families in Recovery from Stroke Trial (FIRST) (n = 272) were interviewed approximately 17 days (baseline) and 6 months (follow-up) after stroke. Cognition was assessed with the Mini Mental State Examination (MMSE) and a summary battery of 7 neuropsychological tests. Median-based regression was used to model cognitive outcomes by level of baseline intimate, personal and organizational social ties and received emotional and instrumental support. Results Baseline social ties and emotional sup- port independently predicted 6-month Cognitive Summary Scores. Emotional support also predicted greater improvements in Cognitive Summary Scores from baseline to the 6-month follow-up. No other social exposures predicted improvements in the MMSE or the Cognitive Summary. Conclusions Our results suggest that emotional support may promote cognitive resilience while social ties provide cognitive reserve that protects against impaired cognition after stroke. Social ties did not predict cognitive recovery however, so reverse causation cannot be ruled out. PMID:18535395
Annual agricultural pesticide use for Midwest Stream-Quality Assessment, 2012-13
Baker, Nancy T.; Stone, Wesley W.
2014-01-01
This report provides estimates of annual agricultural use of 190 pesticide compounds for counties and selected watersheds of Midwestern States for 2012 and 2013 compiled for subsequent analysis by the National Water-Quality Assessment Program, Midwest Stream-Quality Assessment (MSQA). One of the goals of MSQA is to characterize contaminants at perennial-stream sites throughout the Corn Belt. Evaluating pesticide inputs from agricultural sources will aid in that characterization. Crop acres for selected Midwestern crops were obtained from the Cropland Data Layer of the U.S. Department of Agriculture’s National Agricultural Statistics Service and used in conjunction with GfK Kynetec, Inc. proprietary Crop Reporting District-level pesticide-use data to estimate pesticide use for counties and watersheds. Estimated pesticide use (EPest) values were calculated by using both the “EPest-high” and “EPest-low” methods, the distinction being that there are more counties with estimated pesticide use for EPest-high compared to EPest-low, owing to differing assumptions about missing survey data. County-level and watershed-level estimates of annual agricultural pesticide use are provided as downloadable, tab-delimited files for both EPest-high and Epest-low. Summary graphs of MSQA watershed-level pesticide use for selected crops are also provided.
The Yo-Yo intermittent recovery test level 1 is reliable in young high-level soccer players.
Deprez, D; Fransen, J; Lenoir, M; Philippaerts, Rm; Vaeyens, R
2015-03-01
The aim of the study was to investigate test reliability of the Yo-Yo intermittent recovery test level 1 (YYIR1) in 36 high-level youth soccer players, aged between 13 and 18 years. Players were divided into three age groups (U15, U17 and U19) and completed three YYIR1 in three consecutive weeks. Pairwise comparisons were used to investigate test reliability (for distances and heart rate responses) using technical error (TE), coefficient of variation (CV), intra-class correlation (ICC) and limits of agreement (LOA) with Bland-Altman plots. The mean YYIR1 distances for the U15, U17 and U19 groups were 2024 ± 470 m, 2404 ± 347 m and 2547 ± 337 m, respectively. The results revealed that the TEs varied between 74 and 172 m, CVs between 3.0 and 7.5%, and ICCs between 0.87 and 0.95 across all age groups for the YYIR1 distance. For heart rate responses, the TEs varied between 1 and 6 bpm, CVs between 0.7 and 4.8%, and ICCs between 0.73 and 0.97. The small ratio LOA revealed that any two YYIR1 performances in one week will not differ by more than 9 to 28% due to measurement error. In summary, the YYIR1 performance and the physiological responses have proven to be highly reliable in a sample of Belgian high-level youth soccer players, aged between 13 and 18 years. The demonstrated high level of intermittent endurance capacity in all age groups may be used for comparison of other prospective young soccer players.
Section summary: Institutional context, drivers and detectability in REDD+ implementation
Patricia Manley
2013-01-01
REDD+ and Forest DegradationREDD+ implementation requires two key steps: (1) establish a reference emission level or reference level (RL); and (2) monitor performance against the reference level (RL). A monitoring system must be able to monitor the performance of implementing action plans to reduce emissions....
Francis bitter national magnet laboratory annual report, July 1991 through June 1992
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1992-06-01
;Contents: Reports on Laboratory Research Programs--Magneto-Optics and Semiconductor Physics, Superconductivity and Magnetism, Solid State Nuclear Magnetic Resonance, Condensed Matter Chemistry, Biomagnetism, Magnet Technology, Instrumentation, Molecular Biophysics, Carbon Filters and Fullerenes; Reports of Visiting Scientists--Reports of Users of the High Magnetic Field Facility, Reports of the Users of the Pulsed Field Facility, Reports of the Users of the High Field NMR Facility; Appendices--Publications and Meeting Speeches, Organization, Summary of High Magnetic Field Facility Use--January 1, 1984 through June 30, 1992, Geographic Distribution of High Magnetic Field Facility Users (Excluding FBNML Staff), Summary of Educational Activities.
Francis Bitter National Magnet Laboratory annual report, July 1990 through June 1991
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1991-06-01
The contents include: reports on laboratory research programs--magneto-optics and semiconductor physics, magnetism, superconductivity, solid state nuclear magnetic resonance, condensed matter chemistry, biomagnetism, magnet technology, instrumentation, molecular biophysics; reports of visiting scientists--reports of users of the high magnetic field facility, reports of users of the pulsed field facility, reports of users of the SQUID magnetometer and Mossbauer facility, reports of users of the high field NMR facility; appendices--publications and meeting speeches, organization, summary of high magnetic field facility use, user tables, geographic distribution of high magnetic field facility users, summary of educational activities.
Francis Bitter National Magnet Laboratory annual report, July 1989 through June 1990
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1990-01-01
Contents: Reports on laboratory research programs: Magneto-optics and semiconductor physics, Magnetism, Superconductivity, Solid state nuclear magnetic resonance, Condensed matter chemistry, Biomagnetism, Magnet technology, Molecular biophysics; Reports of visiting scientists: Reports of users of the High Magnetic Field Facility, Reports of users of the pulsed field facility, Reports of users of the squid magnetometer and Mossbauer facility, Reports of users of the high field NMR facility; Appendices: Publications and meeting speeches, Organization, Summary of high magnetic field facility use, User tables, Geographic distribution of high magnetic field facility users, Summary of educational activities.
Oxytocin Indexes Relational Distress Following Interpersonal Harms in Women
Tabak, Benjamin A.; McCullough, Michael E.; Szeto, Angela; Mendez, Armando J.; McCabe, Philip M.
2010-01-01
Summary The hypothalamic neuropeptide oxytocin, known for its involvement in social affiliation and bonding in animals, has recently been associated with a host of prosocial behaviors that are beneficial for maintaining positive social relationships in humans. Paradoxically, however, people with high endogenous levels of oxytocin also tend to report relational distress and interpersonal difficulties in their everyday lives. To address these contradictory findings, oxytocin reactivity was measured in response to a well-defined laboratory task in young adult women following recent interpersonal harms. Elevated mean peripheral oxytocin reactivity (but not baseline levels of oxytocin or cortisol reactivity) was associated with increased post-conflict anxiety and decreased levels of forgiveness. These results corroborate previous research implicating oxytocin as a neuroendocrine marker of relational distress, but not general stress, and demonstrate the utility of studying oxytocin in response to naturally occurring relational events. PMID:20688437
NASA Technical Reports Server (NTRS)
1982-01-01
The impact on space systems of three alternative waste mixes was evaluated as part of an effort to investigate the disposal of certain high-level nuclear wastes in space as a complement to mined geologic repositories. A brief overview of the study background, objectives, scope, approach and guidelines, and limitations is presented. The effects of variations in waste mixes on space system concepts were studied in order to provide data for determining relative total system risk benefits resulting from space disposal of the alternative waste mixes. Overall objectives of the NASA-DOE sustaining-level study program are to investigate space disposal concepts which can provide information to support future nuclear waste terminal storage programmatic decisions and to maintain a low level of research activity in this area to provide a baseline for future development should a decision be made to increase the emphasis on this option.
Signaling mechanisms underlying the robustness and tunability of the plant immune network
Kim, Yungil; Tsuda, Kenichi; Igarashi, Daisuke; Hillmer, Rachel A.; Sakakibara, Hitoshi; Myers, Chad L.; Katagiri, Fumiaki
2014-01-01
Summary How does robust and tunable behavior emerge in a complex biological network? We sought to understand this for the signaling network controlling pattern-triggered immunity (PTI) in Arabidopsis. A dynamic network model containing four major signaling sectors, the jasmonate, ethylene, PAD4, and salicylate sectors, which together explain up to 80% of the PTI level, was built using data for dynamic sector activities and PTI levels under exhaustive combinatorial sector perturbations. Our regularized multiple regression model had a high level of predictive power and captured known and unexpected signal flows in the network. The sole inhibitory sector in the model, the ethylene sector, was central to the network robustness via its inhibition of the jasmonate sector. The model's multiple input sites linked specific signal input patterns varying in strength and timing to different network response patterns, indicating a mechanism enabling tunability. PMID:24439900
The 3D Elevation Program: summary for Connecticut
Carswell, William J.
2015-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
Tsukamoto, Shuntaro; Yamashita, Shuya; Kim, Yoon Hee; Kumazoe, Motofumi; Huang, Yuhui; Yamada, Koji; Tachibana, Hirofumi
2012-09-21
(-)-Epigallocatechin-3-O-gallate (EGCG) exhibits anti-tumor activity mediated via the 67-kDa laminin receptor (67LR). In this study, we found that 67LR protein levels are reduced by exposure to low O(2) levels (5%), without affecting the expression of HIF-1α. We also found that EGCG-induced anti-cancer activity is abrogated under low O(2) levels (5%) in various cancer cells. Notably, treatment with the proteasome inhibitor, prevented down-regulation of 67LR and restored sensitivity to EGCG under 5% O(2). In summary, 67LR expression is highly sensitive to O(2) partial pressure, and the activity of EGCG can be regulated in cancer cells by O(2) partial pressure. Copyright © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
The 3D Elevation Program: summary for Mississippi
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Georgia
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Iowa
Carswell, William J.
2015-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Oklahoma
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment (NEEA; Dewberry, 2011) evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Kansas
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Nevada
Carswell, William J.
2015-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Illinois
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Colorado
Carswell, William J.
2013-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Utah
Carswell, William J.
2015-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Delaware
Carswell, William J.
2015-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Massachusetts
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for West Virginia
Carswell, William J.
2015-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for South Carolina
Carswell, William
2015-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for North Carolina
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment (NEEA; Dewberry, 2011) evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the use community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for South Dakota
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment (NEEA; Dewberry, 2011) evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 ifsar data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The new 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: Summary for New Jersey
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Washington
Carswell, William J.
2013-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for New Mexico
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 (table 1) for the conterminous United States and quality level 5 ifsar data (table 1) for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey (USGS), the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Wyoming
Carswell, William J.
2015-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Arizona
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for New Hampshire
Carswell, William J.
2015-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Pennsylvania
Carswell, William J.
2015-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios. The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
The 3D Elevation Program: summary for Arkansas
Carswell, William J.
2014-01-01
The National Enhanced Elevation Assessment evaluated multiple elevation data acquisition options to determine the optimal data quality and data replacement cycle relative to cost to meet the identified requirements of the user community. The evaluation demonstrated that lidar acquisition at quality level 2 for the conterminous United States and quality level 5 interferometric synthetic aperture radar (ifsar) data for Alaska with a 6- to 10-year acquisition cycle provided the highest benefit/cost ratios.The 3D Elevation Program (3DEP) initiative selected an 8-year acquisition cycle for the respective quality levels. 3DEP, managed by the U.S. Geological Survey, the Office of Management and Budget Circular A–16 lead agency for terrestrial elevation data, responds to the growing need for high-quality topographic data and a wide range of other 3D representations of the Nation’s natural and constructed features.
Baker, D; Hann, M
2001-06-01
This study examined the coverage of minor surgery, child health surveillance and chronic disease management for asthma and diabetes in relation to population need and key organisational features of general practice in the 481 primary care groups (PCGs) in England. PCG-level summary scores were developed to estimate the relative availability of all four services and their relative importance in discriminating between high and low levels of service provision. The coverage of services was widespread and, in such circumstances, there was no systematic evidence of poorer service availability for PCGs with higher population need (the 'inverse care' law). Rather this relation was localised, being most predominant for PCGs covering London and its suburbs. In these PCGs, there was no association between indicators of lack of capacity, such as single-handed practice, and levels of service provision.
DOT National Transportation Integrated Search
2012-01-01
Traffic lanes set aside for the use of specific categories of vehicles are becoming more common, from dedicated bicycle lanes on urban roadways to managed lanes for carpools and other high occupancy vehicles on Floridas interstate highways. These ...
Level of Service Program for INDOT Operations : [Technical Summary
DOT National Transportation Integrated Search
2012-01-01
In 2008 the JTRP study SPR-3130, Performance Based Contracting for Roadway Maintenance Operations, revealed the state agencies that have developed a Level of Service (LOS) program benefit. A LOS program can evaluate and determine maintenance performa...
Pavement Structural Evaluation at the Network Level [Tech Brief
DOT National Transportation Integrated Search
2016-03-01
This document is a technical summary of the Federal Highway Administration (FHWA) report, Pavement Structural Evaluation at the Network Level (FHWA-HRT-15-074). It addresses the use of traffic speed deflection devices for the structural evaluation of...
Wyman, Alyssa Jayne; Vyse, Stuart
2008-07-01
The authors asked 52 college students (38 women, 14 men, M age = 19.3 years, SD = 1.3 years) to identify their personality summaries by using a computer-generated astrological natal chart when presented with 1 true summary and 1 bogus one. Similarly, the authors asked participants to identify their true personality profile from real and bogus summaries that the authors derived from the NEO Five-Factor Inventory (NEO-FFI; P. T. Costa Jr. & R. R. McCrae, 1985). Participants identified their real NEO-FFI profiles at a greater-than-chance level but were unable to identify their real astrological summaries. The authors observed a P. T. Barnum effect in the accuracy ratings of both psychological and astrological measures but did not find differences between the odd-numbered (i.e., favorable) signs and the even-numbered (i.e., unfavorable) signs.
NASA Technical Reports Server (NTRS)
Nastrom, G. D.; Jasperson, W. H.
1983-01-01
Temperature data obtained by the Global Atmospheric Sampling Program (GASP) during the period March 1975 to July 1979 are compiled to form flight summaries of static air temperature and a geographic temperature climatology. The flight summaries include the height and location of the coldest observed temperature and the mean flight level, temperature and the standard deviation of temperature for each flight as well as for flight segments. These summaries are ordered by route and month. The temperature climatology was computed for all statistically independent temperture data for each flight. The grid used consists of 5 deg latitude, 30 deg longitude and 2000 feet vertical resolution from FL270 to FL430 for each month of the year. The number of statistically independent observations, their mean, standard deviation and the empirical 98, 50, 16, 2 and .3 probability percentiles are presented.
Shuttle payload interface verification equipment study. Volume 1: Executive summary
NASA Technical Reports Server (NTRS)
1976-01-01
A preliminary design analysis of a stand alone payload integration device (IVE) is provided that is capable of verifying payload compatibility in form, fit and function with the shuttle orbiter prior to on-line payload/orbiter operations. The IVE is a high fidelity replica of the orbiter payload accommodations capable of supporting payload functional checkout and mission simulation. A top level payload integration analysis developed detailed functional flow block diagrams of the payload integration process for the broad spectrum of P/L's and identified degree of orbiter data required by the payload user and potential applications of the IVE.
Thompson, D. E.; Bundy, D. A. P.; Cooper, E. S.; Schantz, P. M.
1986-01-01
The study reports the results of a summary of the prevalence and symptomatology of paediatric toxocariasis in Anse-la-Raye, St. Lucia. The seroprevalence of Toxocara canis among the children, as determined by ELISA, was 86%, the highest level recorded to date. In contrast, the prevalence of infection in dogs was not abnormally high, although the canine population was large and unconstrained compared to that in industrial countries. The presence of infective ova in peridomestic areas and the widespread practice of pica among children in the village probably combine to enhance exposure to infection. PMID:3488844
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
In support of national and subnational decision makers, the 21st Century Power Partnership regularly works with country partners to organize peer-to-peer consultations on critical issues. In March 2014, 21CPP collaborated with the Regulatory Assistance Project - India to host two peer-to-peer exchanges among experts from India, South Africa, Europe, and the United States to discuss the provision of ancillary services, particularly in the context of added variability and uncertainty from renewable energy. This factsheet provides a high level summary of the peer-to-peer consultation.
NASA Technical Reports Server (NTRS)
Trauger, John
2008-01-01
Topics include and overview, science objectives, study objectives, coronagraph types, metrics, ACCESS observatory, laboratory validations, and summary. Individual slides examine ACCESS engineering approach, ACCESS gamut of coronagraph types, coronagraph metrics, ACCESS Discovery Space, coronagraph optical layout, wavefront control on the "level playing field", deformable mirror development for HCIT, laboratory testbed demonstrations, high contract imaging with the HCIT, laboratory coronagraph contrast and stability, model validation and performance predictions, HCIT coronagraph optical layout, Lyot coronagraph on the HCIT, pupil mapping (PIAA), shaped pupils, and vortex phase mask experiments on the HCIT.
Transistor screening evaluation SJ6708H
NASA Technical Reports Server (NTRS)
Barton, J. L.
1978-01-01
A manufacturer was contracted to screen 125 transistors capable of withstanding the high level inductive voltages obtained when switching inductive loads. Planned differences included a change in die bonding to comply with NASA's desire for hard solder die attachment which further necessitated a change in package to conform to the required die mounting system. Evaluation of the electrical performance and recommended changes were made during the preliminary build phase of the program. The following sections are outlined: (1) narrative outline; (2) customer data summary and X-ray reports; (3) device specification; (4) failure analysis reports; (5) test facilities list; and (6) test measurement data.
ERIC Educational Resources Information Center
1985
This study evaluates the process and procedures of the New York City Board of Education in the definition, identification, tracking, and monitoring of student dropouts in selected New York City high schools. The full report is organized in three parts. Part One provides a summary of data obtained (through observations and interviews) from visits…
The NASA High Speed ASE Project: Computational Analyses of a Low-Boom Supersonic Configuration
NASA Technical Reports Server (NTRS)
Silva, Walter A.; DeLaGarza, Antonio; Zink, Scott; Bounajem, Elias G.; Johnson, Christopher; Buonanno, Michael; Sanetrik, Mark D.; Yoo, Seung Y.; Kopasakis, George; Christhilf, David M.;
2014-01-01
A summary of NASA's High Speed Aeroservoelasticity (ASE) project is provided with a focus on a low-boom supersonic configuration developed by Lockheed-Martin and referred to as the N+2 configuration. The summary includes details of the computational models developed to date including a linear finite element model (FEM), linear unsteady aerodynamic models, structured and unstructured CFD grids, and discussion of the FEM development including sizing and structural constraints applied to the N+2 configuration. Linear results obtained to date include linear mode shapes and linear flutter boundaries. In addition to the tasks associated with the N+2 configuration, a summary of the work involving the development of AeroPropulsoServoElasticity (APSE) models is also discussed.
Greenfield, Thomas K.; Kerr, William C.; Bond, Jason; Ye, Yu; Stockwell, Tim
2009-01-01
We investigate several types of graduated frequency (GF) instruments for monitoring drinking patterns. Two studies with 12-month GF measures and daily data were used: (i) the Australian 2004 National Drug Strategy Household Survey (n = 24,109 aged 12+; 22,546 with GF and over 8000 with yesterday data) and (ii) a US methodological study involving a 28-day daily diary plus GF summary measures drawn from the National Alcohol Survey (n = 3,025 screened, 119 eligible study completers). The NDSHS involved (i) “drop and collect” self-completed forms with random sampling methods; the Measurement study (ii) screened 3+ drinkers by telephone and collected 28-day drinking diaries and pre- and post-diary 28-day GFs. We compared mean values for the GF quantity ranges from yesterday’s drinks (study i) and 28-day diaries (study ii), also examining volume influence. Using Yesterday’s drinking, Australian results showed GF quantity range means close to arithmetic midpoints and volume effects only for the lowest two levels (1–2, and 3–4 drinks; p < .001). U.S. calibration results on the GF using 28-day diaries were similar, with a volume effect only at these low quantity levels (p < .001). Means for the highest quantity thresholds were 23.5 drinks for the 20+ (10 gram) drink level (Australia) and 15.5 drinks for the 12+ (14 g) drink level (US). In the US study, summary GF frequency and volume were highly consistent with diary-based counterparts. A conclusion is that algorithms for computing volume may be refined using validation data. We suggest measurement methods may be improved by taking better account of empirical drink ethanol content. PMID:21197381
Smith, Jennifer A; Zhao, Wei; Wang, Xu; Ratliff, Scott M; Mukherjee, Bhramar; Kardia, Sharon L R; Liu, Yongmei; Roux, Ava V Diez; Needham, Belinda L
2017-08-01
Living in a disadvantaged neighborhood is associated with poor health outcomes even after accounting for individual-level socioeconomic factors. The chronic stress of unfavorable neighborhood conditions may lead to dysregulation of the stress reactivity and inflammatory pathways, potentially mediated through epigenetic mechanisms such as DNA methylation. We used multi-level models to examine the relationship between 2 neighborhood conditions and methylation levels of 18 genes related to stress reactivity and inflammation in purified monocytes from 1,226 participants of the Multi-Ethnic Study of Atherosclerosis (MESA), a population-based sample of US adults. Neighborhood socioeconomic disadvantage, a summary of 16 census-based metrics, was associated with DNA methylation [False discovery rate (FDR) q-value ≤ 0.1] in 2 out of 7 stress-related genes evaluated (CRF, SLC6A4) and 2 out of 11 inflammation-related genes (F8, TLR1). Neighborhood social environment, a summary measure of aesthetic quality, safety, and social cohesion, was associated with methylation in 4 of the 7 stress-related genes (AVP, BDNF, FKBP5, SLC6A4) and 7 of the 11 inflammation-related genes (CCL1, CD1D, F8, KLRG1, NLRP12, SLAMF7, TLR1). High socioeconomic disadvantage and worse social environment were primarily associated with increased methylation. In 5 genes with significant associations between neighborhood and methylation (FKBP5, CD1D, F8, KLRG1, NLRP12), methylation was associated with gene expression of at least one transcript. These results demonstrate that multiple dimensions of neighborhood context may influence methylation levels and subsequent gene expression of stress- and inflammation-related genes, even after accounting for individual socioeconomic factors. Further elucidating the molecular mechanisms underlying these relationships will be important for understanding the etiology of health disparities.
Acute-onset floaters and flashes: is this patient at risk for retinal detachment?
Hollands, Hussein; Johnson, Davin; Brox, Anya C; Almeida, David; Simel, David L; Sharma, Sanjay
2009-11-25
Acute onset of monocular floaters and/or flashes represents a common presentation to primary care physicians, and the most likely diagnosis is posterior vitreous detachment (PVD). A significant proportion of patients with acute PVD develop an associated retinal tear that can lead to retinal detachment and permanent vision loss if left untreated. To quantify the association between relevant clinical variables and risk of retinal tear in patients presenting with acute-onset floaters and/or flashes and PVD. Structured MEDLINE (January 1950-September 2009) and EMBASE (January 1980-September 2009) searches and a hand search of references and citations of retrieved articles yielded 17 relevant studies. Studies of high-level methods that related elements of the history or physical examination in patients presenting with floaters and/or flashes and PVD to the likelihood of retinal tear. For patients with acute onset of floaters and/or flashes who are self-referred or referred to an ophthalmologist, the prevalence of retinal tear is 14% (95% confidence interval [CI], 12%-16%). Subjective visual reduction is the most important symptom associated with retinal tear (likelihood ratio [LR], 5.0; 95% CI, 3.1-8.1). Vitreous hemorrhage on slitlamp biomicroscopy is the best-studied finding with the narrowest positive LR for retinal tear (summary LR, 10; 95% CI, 5.1-20). Absence of vitreous pigment during this examination is the best-studied finding with the narrowest negative LR (summary LR, 0.23; 95% CI, 0.12-0.43). Patients initially diagnosed as having uncomplicated PVD have a 3.4% chance of a retinal tear within 6 weeks. The risk increases with new onset of at least 10 floaters (summary LR, 8.1-36) or subjective visual reduction (summary LR, 2.3-17) during this period. Primary care physicians should evaluate patients with acute-onset floaters and/or flashes due to suspected PVD, or patients with known PVD and a change in symptoms, for high-risk features of retinal tear and detachment. Physicians should always assess these patients' visual acuity. Patients at increased risk should be triaged for urgent ophthalmologic assessment.
Schlesinger, Sabrina; Sonntag, Svenja R.
2016-01-01
Background A growing number of studies linked elevated concentrations of circulating asymmetric (ADMA) and symmetric (SDMA) dimethylarginine to mortality and cardiovascular disease (CVD) events. To summarize the evidence, we conducted a systematic review and quantified associations of ADMA and SDMA with the risks of all-cause mortality and incident CVD in meta-analyses accounting for different populations and methodological approaches of the studies. Methods Relevant studies were identified in PubMed until February 2015. We used random effect models to obtain summary relative risks (RR) and 95% confidence intervals (95%CIs), comparing top versus bottom tertiles. Dose-response relations were assessed by restricted cubic spline regression models and potential non-linearity was evaluated using a likelihood ratio test. Heterogeneity between subgroups was assessed by meta-regression analysis. Results For ADMA, 34 studies (total n = 32,428) investigating associations with all-cause mortality (events = 5,035) and 30 studies (total n = 30,624) investigating the association with incident CVD (events = 3,396) were included. The summary RRs (95%CI) for all-cause mortality were 1.52 (1.37–1.68) and for CVD 1.33 (1.22–1.45), comparing high versus low ADMA concentrations. Slight differences were observed across study populations and methodological approaches, with the strongest association of ADMA being reported with all-cause mortality in critically ill patients. For SDMA, 17 studies (total n = 18,163) were included for all-cause mortality (events = 2,903), and 13 studies (total n = 16,807) for CVD (events = 1,534). High vs. low levels of SDMA, were associated with increased risk of all-cause mortality [summary RR (95%CI): 1.31 (1.18–1.46)] and CVD [summary RR (95%CI): 1.36 (1.10–1.68) Strongest associations were observed in general population samples. Conclusions The dimethylarginines ADMA and SDMA are independent risk markers for all-cause mortality and CVD across different populations and methodological approaches. PMID:27812151
Same But Different: FIM Summary Scores May Mask Variability in Physical Functioning Profiles.
Fisher, Steve R; Middleton, Addie; Graham, James E; Ottenbacher, Kenneth J
2018-02-08
To examine how similar summary scores of physical functioning using the FIM can represent different patient clinical profiles. Retrospective cohort study. Inpatient rehabilitation facilities. Medicare fee-for-service beneficiaries (N=765,441) discharged from inpatient rehabilitation. Not applicable. We used patients' scores on items of the FIM to quantify their level of independence on both self-care and mobility domains. We then identified patients as requiring "no physical assistance" at discharge from inpatient rehabilitation by using a rule and score-based approach. In those patients with FIM self-care and mobility summary scores suggesting no physical assistance needed, we found that physical assistance was in fact needed frequently in bathroom-related activities (eg, continence, toilet and tub transfers, hygiene, clothes management) and with stairs. It was not uncommon for actual performance to be lower than what may be suggested by a summary score of those domains. Further research is needed to create clinically meaningful descriptions of summary scores from combined performances on individual items of physical functioning. Copyright © 2018 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.
Bauer, Paige V; Duca, Frank A; Waise, T M Zaved; Dranse, Helen J; Rasmussen, Brittany A; Puri, Akshita; Rasti, Mozhgan; O'Brien, Catherine A; Lam, Tony K T
2018-03-06
Long-chain acyl-CoA synthetase (ACSL)-dependent upper small intestinal lipid metabolism activates pre-absorptive pathways to regulate metabolic homeostasis, but whether changes in the upper small intestinal microbiota alter specific fatty acid-dependent pathways to impact glucose homeostasis remains unknown. We here first find that upper small intestinal infusion of Intralipid, oleic acid, or linoleic acid pre-absorptively increases glucose tolerance and lowers glucose production in rodents. High-fat feeding impairs pre-absorptive fatty acid sensing and reduces upper small intestinal Lactobacillus gasseri levels and ACSL3 expression. Transplantation of healthy upper small intestinal microbiota to high-fat-fed rodents restores L. gasseri levels and fatty acid sensing via increased ACSL3 expression, while L. gasseri probiotic administration to non-transplanted high-fat-fed rodents is sufficient to restore upper small intestinal ACSL3 expression and fatty acid sensing. In summary, we unveil a glucoregulatory role of upper small intestinal L. gasseri that impacts an ACSL3-dependent glucoregulatory fatty acid-sensing pathway. Copyright © 2018 Elsevier Inc. All rights reserved.
PROMIS (Procurement Management Information System)
NASA Technical Reports Server (NTRS)
1987-01-01
The PROcurement Management Information System (PROMIS) provides both detailed and summary level information on all procurement actions performed within NASA's procurement offices at Marshall Space Flight Center (MSFC). It provides not only on-line access, but also schedules procurement actions, monitors their progress, and updates Forecast Award Dates. Except for a few computational routines coded in FORTRAN, the majority of the systems is coded in a high level language called NATURAL. A relational Data Base Management System called ADABAS is utilized. Certain fields, called descriptors, are set up on each file to allow the selection of records based on a specified value or range of values. The use of like descriptors on different files serves as the link between the falls, thus producing a relational data base. Twenty related files are currently being maintained on PROMIS.
Executive Summary Report - FY80 Geotechnical Siting Investigations.
1980-11-30
MX siting investigation, geotech- nical summary, prime characterization sites, Rio Grande /Highlands Candidate Siting Province report. TR-26d , 19781...s * Subsurface projectlro of to sul rock limits ab ser i Oelneation of ro-k f o- Geologic high (-7000 !ps -) w- we velocities -Obta r Borings
A Comprehensive Review of the Literature on Summary of Performance
ERIC Educational Resources Information Center
Richter, Sharon McCormack; Mazzotti, Valerie L.
2011-01-01
The Individuals with Disabilities Education Act (2004) requires local education agencies to provide students with disabilities exiting high school with a Summary of Performance document, which includes academic and functional performance information and recommendations for helping the student reach postsecondary goals. However, the federal mandate…
2017-06-01
factors related to CD. Health Level 7 (HL7)-formatted microbiology and chemistry data identified CDI. These infections were matched to HL7-formatted...resistant organisms . iii C. difficile in the MHS: Annual Summary 2016 Prepared June 2017 EpiData Center Department NMCPHC-EDC-TR-364...been discussed in a previous report (CY 2015 CDI annual report 1 ). The EDC also monitors other multidrug-resistant organisms (MDROs) of interest
ERIC Educational Resources Information Center
Christophersen, Kjell A.; Robison, M. Henry
This document contains and executive summary, main report, and detailed results by entry level of education, gender and ethnicity. The parts of this document examine the ways in which the State of Oklahoma economy benefits from the presence of the 14 community college districts in the state. The colleges serve an unduplicated headcount of 106,201…
Presenting SAPUSS: Solving Aerosol Problem by Using Synergistic Strategies in Barcelona, Spain
NASA Astrophysics Data System (ADS)
Dall'Osto, M.; Querol, X.; Alastuey, A.; Minguillon, M. C.; Alier, M.; Amato, F.; Brines, M.; Cusack, M.; Grimalt, J. O.; Karanasiou, A.; Moreno, T.; Pandolfi, M.; Pey, J.; Reche, C.; Ripoll, A.; Tauler, R.; Van Drooge, B. L.; Viana, M.; Harrison, R. M.; Gietl, J.; Beddows, D.; Bloss, W.; O'Dowd, C.; Ceburnis, D.; Martucci, G.; Ng, N. L.; Worsnop, D.; Wenger, J.; Mc Gillicuddy, E.; Sodeau, J.; Healy, R.; Lucarelli, F.; Nava, S.; Jimenez, J. L.; Gomez Moreno, F.; Artinano, B.; Prévôt, A. S. H.; Pfaffenberger, L.; Frey, S.; Wilsenack, F.; Casabona, D.; Jiménez-Guerrero, P.; Gross, D.; Cots, N.
2013-09-01
This paper presents the summary of the key objectives, instrumentation and logistic details, goals, and initial scientific findings of the European Marie Curie Action SAPUSS project carried out in the western Mediterranean Basin (WMB) during September-October in autumn 2010. The key SAPUSS objective is to deduce aerosol source characteristics and to understand the atmospheric processes responsible for their generations and transformations - both horizontally and vertically in the Mediterranean urban environment. In order to achieve so, the unique approach of SAPUSS is the concurrent measurements of aerosols with multiple techniques occurring simultaneously in six monitoring sites around the city of Barcelona (NE Spain): a main road traffic site, two urban background sites, a regional background site and two urban tower sites (150 m and 545 m above sea level, 150 m and 80 m above ground, respectively). SAPUSS allows us to advance our knowledge sensibly of the atmospheric chemistry and physics of the urban Mediterranean environment. This is well achieved only because of both the three dimensional spatial scale and the high sampling time resolution used. During SAPUSS different meteorological regimes were encountered, including warm Saharan, cold Atlantic, wet European and stagnant regional ones. The different meteorology of such regimes is herein described. Additionally, we report the trends of the parameters regulated by air quality purposes (both gaseous and aerosol mass concentrations); and we also compare the six monitoring sites. High levels of traffic-related gaseous pollutants were measured at the urban ground level monitoring sites, whereas layers of tropospheric ozone were recorded at tower levels. Particularly, tower level night-time average ozone concentrations (80 ± 25 μg m-3) were up to double compared to ground level ones. The examination of the vertical profiles clearly shows the predominant influence of NOx on ozone concentrations, and a source of ozone aloft. Analysis of the particulate matter (PM) mass concentrations shows an enhancement of coarse particles (PM2.5-10) at the urban ground level (+64%, average 11.7 μg m-3) but of fine ones (PM1) at urban tower level (+28%, average 14.4 μg m-3). These results show complex dynamics of the size-resolved PM mass at both horizontal and vertical levels of the study area. Preliminary modelling findings reveal an underestimation of the fine accumulation aerosols. In summary, this paper lays the foundation of SAPUSS, an integrated study of relevance to many other similar urban Mediterranean coastal environment sites.
Fast and accurate imputation of summary statistics enhances evidence of functional enrichment.
Pasaniuc, Bogdan; Zaitlen, Noah; Shi, Huwenbo; Bhatia, Gaurav; Gusev, Alexander; Pickrell, Joseph; Hirschhorn, Joel; Strachan, David P; Patterson, Nick; Price, Alkes L
2014-10-15
Imputation using external reference panels (e.g. 1000 Genomes) is a widely used approach for increasing power in genome-wide association studies and meta-analysis. Existing hidden Markov models (HMM)-based imputation approaches require individual-level genotypes. Here, we develop a new method for Gaussian imputation from summary association statistics, a type of data that is becoming widely available. In simulations using 1000 Genomes (1000G) data, this method recovers 84% (54%) of the effective sample size for common (>5%) and low-frequency (1-5%) variants [increasing to 87% (60%) when summary linkage disequilibrium information is available from target samples] versus the gold standard of 89% (67%) for HMM-based imputation, which cannot be applied to summary statistics. Our approach accounts for the limited sample size of the reference panel, a crucial step to eliminate false-positive associations, and it is computationally very fast. As an empirical demonstration, we apply our method to seven case-control phenotypes from the Wellcome Trust Case Control Consortium (WTCCC) data and a study of height in the British 1958 birth cohort (1958BC). Gaussian imputation from summary statistics recovers 95% (105%) of the effective sample size (as quantified by the ratio of [Formula: see text] association statistics) compared with HMM-based imputation from individual-level genotypes at the 227 (176) published single nucleotide polymorphisms (SNPs) in the WTCCC (1958BC height) data. In addition, for publicly available summary statistics from large meta-analyses of four lipid traits, we publicly release imputed summary statistics at 1000G SNPs, which could not have been obtained using previously published methods, and demonstrate their accuracy by masking subsets of the data. We show that 1000G imputation using our approach increases the magnitude and statistical evidence of enrichment at genic versus non-genic loci for these traits, as compared with an analysis without 1000G imputation. Thus, imputation of summary statistics will be a valuable tool in future functional enrichment analyses. Publicly available software package available at http://bogdan.bioinformatics.ucla.edu/software/. bpasaniuc@mednet.ucla.edu or aprice@hsph.harvard.edu Supplementary materials are available at Bioinformatics online. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
Levels of Evidence: Cancer Screening and Prevention Studies (PDQ®)—Health Professional Version
Levels of Evidence for Cancer Screening and Prevention Studies explains how to weigh the strength of the evidence obtained in cited research studies. Get detailed information on this formal ranking system in this summary for clinicians.
Levels of Evidence: Integrative Therapies Human Studies (PDQ®)—Health Professional Version
Levels of Evidence for Integrative, Alternative, and Complementary Therapies is about how to weigh the strength of the evidence obtained in cited research studies. Get detailed information this formal ranking system in this summary for clinicians.
Ambient noise level measurements in proposed Florida airport area
DOT National Transportation Integrated Search
1972-12-31
This report documents the measurement results made at ten locations near the three remaining sites being studied for the "South Florida Regional Report." Tabulated data display a summary of the measured noise levels at each location expressed as nois...
Awasthi, Ashish; Pandey, C M; Chauhan, Rajesh K; Singh, Uttam
2016-08-05
To examine the level and trend in the coverage gap of a set of interventions of maternal and child health services using a summary index and to assess the disparity in usage of maternal and child health services in the districts of high focus states of India. Data for the present study are taken from the Annual Health Survey (AHS), 2010-2013 and Census of India, 2011. This study used secondary data from states having higher mortality and fertility rates, termed as high focus states in India. District-level information regarding children aged 12-23 months and ever married women aged 15-49 years has been extracted from the AHS (2010-2013), and household amenities, female literacy and main workforce information has been obtained from the Census of India 2011. 2 summary indexes were calculated first for maternal and child health services and another for socioeconomic and development status, using data from AHS and Census. Cronbach's α was used to assess the internal consistency of the items used in the index. The result shows that the coverage gap is highest in Uttar Pradesh (37%) and lowest in Madhya Pradesh (21%). Converge gap and socioeconomic development are negatively correlated (r=-0.49, p=0.01). The average coverage gap was highest in the lowest quintile of socioeconomic development. There was an absolute change of 1.5% per year in coverage gap during 2009-2013. In regression analysis, the coefficient of determination was 0.24, β=-30.05, p=0.01 for a negative relationship between socioeconomic development and coverage gap. There is a significant disparity in the usage of maternal and child healthcare services in the districts of India. Resource-rich people (urban residents and richest quintile) are way ahead of marginalised people (rural residents and poorest quintile) in the usage of healthcare services. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/
Schnorpfeil, Pia; Noll, Alexander; Wirtz, Petra; Schulze, Renate; Ehlert, Ulrike; Frey, Karl; Fischer, Joachim E
2002-10-01
Vital exhaustion, a construct overlapping with burnout, is an independent risk factor for adverse health outcomes, including cardiovascular disease. We aimed to assess vital exhaustion in employees in the manufacturing industry and identify work characteristics associated with exhaustion. Cross-sectional study. A stratified, representative random sample of employees from a manufacturing plant for airplane parts and assemblies was invited ( n=647), of whom 537 employees (83% accrual) volunteered to participate. Scores obtained by the nine-item Shortened Maastricht Exhaustion Questionnaire were compared with the mental and physical summary scales of the SF-12 General Health Survey and to a list of 20 health complaints. Pathogenic and salutogenic work characteristics were assessed by the self-reported 52-item, 13-subscale SALSA questionnaire. Vital exhaustion correlated with the mental summary score of the SF-12 and the number of health complaints and was positively associated with age. Exhaustion was not associated with gender, position (socio-economic status) or being on a wage (paid per completed item up to a contracted amount) or salary (payment as fixed monthly income). The instrument identified departments with high levels of exhaustion. Of the observed variance in exhaustion, 29% was explained by age, department, and five work characteristics: High levels of exhaustion (score >10) were related to excessive workload or qualitative demands (scoring in the highest quartile; OR(adj) 7.5; 95% CI 2.4-23), to adverse physical work conditions (OR(adj) 6.9; 95% CI 2.2-21), to adverse co-worker behavior (OR(adj) 4.8; 95% CI 1.4-16), to qualification potential (OR(adj) 0.32; 95% CI 0.11-0.97), and to social support by co-workers (OR(adj) 0.34; 95% CI 0.13-0.99), respectively. The nine-item instrument allows rapid screening of employees for self-reported levels of exhaustion. Besides physical work conditions and workload, absence or presence of social support by co-workers is strongly associated with exhaustion.
Bronnikov, G E; Kulagina, T P; Aripovskii, A V; Kramarova, L I
2015-06-01
Activities of mitochondrial electron transport chain enzymes NADH-CoQ oxidoreductase (complex I), cytochrome C-oxidase (complex IV), and citrate synthase were measured by spectrophotometry in m. quadriceps femoris homogenate from old rats receiving olive oil with the ration. Reduced activities of complexes I and IV in old animals were restored to the level of young animals after 6-week consumption of olive oil. Activity of citrate synthase did not change with age. Positive effect of olive oil on fatty-acid composition of the muscle tissue in old animals was demonstrated. The content of summary monounsaturated fatty acids, reduced with aging, and of summary polyunsaturated ones, increasing with age, were restored in old rats to the levels virtually not differing from the levels of young animals.
Beh, Boon Kee; Kong, Joan; Ho, Wan Yong; Mohd Yusof, Hamidah; Hussin, Aminuddin bin; Jaganath, Indu Bala; Alitheen, Noorjahan Banu; Jamaluddin, Anisah
2014-01-01
Fermented red yeast rice has been traditionally consumed as medication in Asian cuisine. This study aimed to determine the in vivo hypocholesterolemic and antioxidant effects of fermented red yeast rice water extract produced using Malaysian Agricultural Research and Development Institute (MARDI) Monascus purpureus strains in mice fed with high cholesterol diet. Absence of monacolin-k, lower level of γ-aminobutyric acid (GABA), higher content of total amino acids, and antioxidant activities were detected in MARDI fermented red yeast rice water extract (MFRYR). In vivo MFRYR treatment on hypercholesterolemic mice recorded similar lipid lowering effect as commercial red yeast rice extract (CRYR) as it helps to reduce the elevated serum liver enzyme and increased the antioxidant levels in liver. This effect was also associated with the upregulation of apolipoproteins-E and inhibition of Von Willebrand factor expression. In summary, MFRYR enriched in antioxidant and amino acid without monacolin-k showed similar hypocholesterolemic effect as CRYR that was rich in monacolin-k and GABA. PMID:25031606
An implementation research agenda
Eccles, Martin P; Armstrong, David; Baker, Richard; Cleary, Kevin; Davies, Huw; Davies, Stephen; Glasziou, Paul; Ilott, Irene; Kinmonth, Ann-Louise; Leng, Gillian; Logan, Stuart; Marteau, Theresa; Michie, Susan; Rogers, Hugh; Rycroft-Malone, Jo; Sibbald, Bonnie
2009-01-01
In October 2006, the Chief Medical Officer (CMO) of England asked Professor Sir John Tooke to chair a High Level Group on Clinical Effectiveness in response to the chapter 'Waste not, want not' in the CMOs 2005 annual report 'On the State of the Public Health'. The high level group made recommendations to the CMO to address possible ways forward to improve clinical effectiveness in the UK National Health Service (NHS) and promote clinical engagement to deliver this. The report contained a short section on research needs that emerged from the process of writing the report, but in order to more fully identify the relevant research agenda Professor Sir John Tooke asked Professor Martin Eccles to convene an expert group – the Clinical Effectiveness Research Agenda Group (CERAG) – to define the research agenda. The CERAG's terms of reference were 'to further elaborate the research agenda in relation to pursuing clinically effective practice within the (UK) National Health Service'. This editorial presents the summary of the CERAG report and recommendations. PMID:19351400
Cantó, Carles; Houtkooper, Riekelt H.; Pirinen, Eija; Youn, Dou Y.; Oosterveer, Maaike H.; Cen, Yana; Fernandez-Marcos, Pablo J.; Yamamoto, Hiroyasu; Andreux, Pénélope A.; Cettour-Rose, Philippe; Gademann, Karl; Rinsch, Chris; Schoonjans, Kristina; Sauve, Anthony A.; Auwerx, Johan
2013-01-01
SUMMARY As NAD+ is a rate-limiting co-substrate for the sirtuin enzymes, its modulation is emerging as a valuable tool to regulate sirtuin function and, consequently, oxidative metabolism. In line with this premise, decreased activity of PARP-1 or CD38 —both NAD+ consumers— increases NAD+ bioavailability, resulting in SIRT1 activation and protection against metabolic disease. Here we evaluated whether similar effects could be achieved by increasing the supply of nicotinamide riboside (NR), a recently described natural NAD+ precursor with the ability to increase NAD+ levels, Sir2-dependent gene silencing and replicative lifespan in yeast. We show that NR supplementation in mammalian cells and mouse tissues increases NAD+ levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Consequently, our results indicate that the natural vitamin, NR, could be used as a nutritional supplement to ameliorate metabolic and age-related disorders characterized by defective mitochondrial function. PMID:22682224
Public health campaigns and obesity - a critique
2011-01-01
Background Controlling obesity has become one of the highest priorities for public health practitioners in developed countries. In the absence of safe, effective and widely accessible high-risk approaches (e.g. drugs and surgery) attention has focussed on community-based approaches and social marketing campaigns as the most appropriate form of intervention. However there is limited evidence in support of substantial effectiveness of such interventions. Discussion To date there is little evidence that community-based interventions and social marketing campaigns specifically targeting obesity provide substantial or lasting benefit. Concerns have been raised about potential negative effects created by a focus of these interventions on body shape and size, and of the associated media targeting of obesity. Summary A more appropriate strategy would be to enact high-level policy and legislative changes to alter the obesogenic environments in which we live by providing incentives for healthy eating and increased levels of physical activity. Research is also needed to improve treatments available for individuals already obese. PMID:21352562
Wen, Haiguang; Shi, Junxing; Chen, Wei; Liu, Zhongming
2018-02-28
The brain represents visual objects with topographic cortical patterns. To address how distributed visual representations enable object categorization, we established predictive encoding models based on a deep residual network, and trained them to predict cortical responses to natural movies. Using this predictive model, we mapped human cortical representations to 64,000 visual objects from 80 categories with high throughput and accuracy. Such representations covered both the ventral and dorsal pathways, reflected multiple levels of object features, and preserved semantic relationships between categories. In the entire visual cortex, object representations were organized into three clusters of categories: biological objects, non-biological objects, and background scenes. In a finer scale specific to each cluster, object representations revealed sub-clusters for further categorization. Such hierarchical clustering of category representations was mostly contributed by cortical representations of object features from middle to high levels. In summary, this study demonstrates a useful computational strategy to characterize the cortical organization and representations of visual features for rapid categorization.
Statistical Summary of Missouri Higher Education, 1999-2000.
ERIC Educational Resources Information Center
Missouri State Coordinating Board for Higher Education, Jefferson City.
This report provides a statistical summary of higher education in Missouri for the 1999-2000 academic year. More than 74 tables provide data on: advanced placement enrollment in secondary schools, American College Testing program scores by institutional sector, high school rankings by institutional sector, the Missouri Coordinating Board for…
The Formal Structure of School Summaries.
ERIC Educational Resources Information Center
Flottum, Kjersti
A study compared text summaries produced by French high school students and those written by experts. The study's objective was to determine how language users distinguish the essential from the peripheral information, to describe the summarizing process, and to apply the macrostructure theory to the process of summarizing. The summarized texts…