Molecular Nitrogen Fluorescence Lidar for Remote Sensing of the Auroral Ionosphere

DTIC Science & Technology

1994-02-24

AD-A280 716 PL-TR-94-2044 MOLECULAR NITROGEN FLUORESCENCE LIDAR FOR REMOTE SENSING OF THE AURORAL IONOSPHERE Richard Garner Michael Burka...6. AUTHOR(S) Richard Garner Contract F19628-92-C-0160 Michael Burka 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION...by Richard Dickmuaz of the HIPAS observatory and by Ralph Wuerker of UCLA PPL. 29 le

Binaural Processing of Multiple Sound Sources

DTIC Science & Technology

2016-08-18

Sound Source Localization Identification, and Sound Source Localization When Listeners Move. The CI research was also supported by an NIH grant...8217Cochlear Implant Performance in Realistic Listening Environments,’ Dr. Michael Dorman, Principal Investigator, Dr. William Yost unpaid advisor. The other... Listeners Move. The CI research was also supported by an NIH grant (“Cochlear Implant Performance in Realistic Listening Environments,” Dr. Michael Dorman

76 FR 59416 - Senior Executive Service Performance Review Board

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-26

... Anderson, Gary Anderson, Penny Andrews, John Armstrong, Charles R. Armstrong, Sue Athmann, Ronald Ayala, Janice Barber, Delores Baroukh, Nader Bartoldus, Charles Bathurst, Donald Bauhs, Kim Beagles, James... Butcher, Michael Button, Christopher Byrne, Michael Byrne, Sean J. Cahill, Donna L. Callahan, Mary Ellen...

77 FR 62490 - Performance Review Board Appointments

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-15

...; Gutter, Karis T.; Harden, Krysta.; Hipp, Janie; Holtzman, Max T.; Jett, Carole E.; Jones, Carmen....; Chasteen, G. Taylor; Christian, Lisa A.; Clanton, Michael W.; Coffee, Richard; Farington, Kim S.; Foster....; Watts, Michael; White, John S.; White, Sharmian L.; Wilburn, Curtis; Wilusz, Lisa; Young, Benjamin...

Facile construction of macroporous hybrid monoliths via thiol-methacrylate Michael addition click reaction for capillary liquid chromatography.

PubMed

Lin, Hui; Ou, Junjie; Liu, Zhongshan; Wang, Hongwei; Dong, Jing; Zou, Hanfa

2015-01-30

A facile approach based on thiol-methacrylate Michael addition click reaction was developed for construction of porous hybrid monolithic materials. Three hybrid monoliths were prepared via thiol-methacrylate click polymerization by using methacrylate-polyhedral oligomeric silsesquioxane (POSS) (cage mixture, n=8, 10, 12, POSS-MA) and three multi-thiol crosslinkers, 1,6-hexanedithiol (HDT), trimethylolpropane tris(3-mercaptopropionate) (TPTM) and pentaerythritol tetrakis(3-mercaptopropionate) (PTM), respectively, in the presence of porogenic solvents (n-propanol and PEG 200) and a catalyst (dimethylphenylphosphine, DMPP). The obtained monoliths possessed high thermal and chemical stabilities. Besides, they all exhibited high column efficiencies and excellent separation abilities in capillary liquid chromatography (cLC). The highest column efficiency could reach ca. 195,000N/m for butylbenzene on the monolith prepared with POSS-MA and TPTM (monolith POSS-TPTM) in reversed-phase (RP) mode at 0.64mm/s. Good chromatographic performance were all achieved in the separations of polycyclic aromatic hydrocarbons (PAHs), phenols, anilines, EPA 610 as well as bovine serum albumin (BSA) digest. The high column efficiencies in the range of 51,400-117,000N/m (achieved on the monolith POSS-PTM in RP mode) convincingly demonstrated the high separation abilities of these thiol-methacrylate based hybrid monoliths. All the results demonstrated the feasibility of the phosphines catalyzed thiol-methacrylate Michael addition click reaction in fabrication of monolithic columns with high efficiency for cLC applications. Copyright © 2014 Elsevier B.V. All rights reserved.

CytoSPADE: high-performance analysis and visualization of high-dimensional cytometry data

PubMed Central

Linderman, Michael D.; Simonds, Erin F.; Qiu, Peng; Bruggner, Robert V.; Sheode, Ketaki; Meng, Teresa H.; Plevritis, Sylvia K.; Nolan, Garry P.

2012-01-01

Motivation: Recent advances in flow cytometry enable simultaneous single-cell measurement of 30+ surface and intracellular proteins. CytoSPADE is a high-performance implementation of an interface for the Spanning-tree Progression Analysis of Density-normalized Events algorithm for tree-based analysis and visualization of this high-dimensional cytometry data. Availability: Source code and binaries are freely available at http://cytospade.org and via Bioconductor version 2.10 onwards for Linux, OSX and Windows. CytoSPADE is implemented in R, C++ and Java. Contact: michael.linderman@mssm.edu Supplementary Information: Additional documentation available at http://cytospade.org. PMID:22782546

Hole and Electron Extraction Layers Based on Graphene Oxide Derivatives for High-Performance Bulk Heterojunction Solar Cells

DTIC Science & Technology

2012-01-01

Yuhua Xue , Yunxiang Gao , Dingshan Yu , Michael Durstock , and Liming Dai * Hole and Electron Extraction Layers Based on Graphene Oxide...H. Wu , L. Chen , S. Su , Y. Cao , Adv. Mater. 2011 , 23 , 4636 . [ 29 ] T.-Y. Chu , S.-W. Tsang , J. Zhou , P. G. Verly , J

Investigating the Mobility of Light Autonomous Tracked Vehicles using a High Performance Computing Simulation Capability

DTIC Science & Technology

2012-08-01

Madison, WI 53706 David Lamb Paramsothy Jayakumar Michael Letherwood U.S. Army TARDEC Warren, MI 48397 Abhinandan Jain Marco Quadrelli Jet Propulsion...PROGRAM ELEMENT NUMBER 6. AUTHOR(S) David Lamb; Paramsothy Jayakumar ; Mike Letherwood; Dan Negrut; Abhinandan Jain 5d. PROJECT NUMBER 5e. TASK

Synthesis, chemical reactivity as Michael acceptors, and biological potency of monocyclic cyanoenones, novel and highly potent anti-inflammatory and cytoprotective agents.

PubMed

Zheng, Suqing; Santosh Laxmi, Y R; David, Emilie; Dinkova-Kostova, Albena T; Shiavoni, Katherine H; Ren, Yanqing; Zheng, Ying; Trevino, Isaac; Bumeister, Ronald; Ojima, Iwao; Wigley, W Christian; Bliska, James B; Mierke, Dale F; Honda, Tadashi

2012-05-24

Novel monocyclic cyanoenones examined to date display unique features regarding chemical reactivity as Michael acceptors and biological potency. Remarkably, in some biological assays, the simple structure is more potent than pentacyclic triterpenoids (e.g., CDDO and bardoxolone methyl) and tricycles (e.g., TBE-31). Among monocyclic cyanoenones, 1 is a highly reactive Michael acceptor with thiol nucleophiles. Furthermore, an important feature of 1 is that its Michael addition is reversible. For the inhibition of NO production, 1 shows the highest potency. Notably, its potency is about three times higher than CDDO, whose methyl ester (bardoxolone methyl) is presently in phase III clinical trials. For the induction of NQO1, 1 also demonstrated the highest potency. These results suggest that the reactivity of these Michael acceptors is closely related to their biological potency. Interestingly, in LPS-stimulated macrophages, 1 causes apoptosis and inhibits secretion of TNF-α and IL-1β with potencies that are higher than those of bardoxolone methyl and TBE-31.

HIGHLY DISATEREOSELECTIVE MICHAEL ADDITION OF FLAVANONE TO ITS CHALCONE PRECURSOR UNDER SOLVENT-FREE CONDITIONS USING MICROWAVES [POSTER

EPA Science Inventory

Substituted 2'-hydroxychalcones were found to give an equilibrium mixture of the starting chalcone and the corresponding flavanone inf 4.6-1:3 ratio in the presence of DBU gave two hitherto unknown diasteromeric dimers in a highly diastereoselective Michael addition of the carban...

What Works, Works Everywhere: Q&A with Michael Barber

ERIC Educational Resources Information Center

Crow, Tracy

2009-01-01

This article presents an interview with Michael Barber, a partner at McKinsey & Company, leading its global education practice. He has been working on major challenges of performance, organization, and reform in government and the public services, especially education, in the U.S., U.K., and other countries. Barber was instrumental in preparing…

Green Propellant Infusion Mission

NASA Image and Video Library

2013-07-09

Dr. Michael Gazarik, Associate Administrator, NASA Space Technology Mission Directorate, answers a reporter's question at a Green Propellant Infusion Mission press conference at the Reserve Officers Association, Tuesday, July 9, 2013 in Washington. The NASA GPIM program, led by Ball Aerospace in conjunction with Aerojet Rocketdyne, is demonstrating a high-performance "green" fuel in space. The propellant used on this mission offers nearly 50 percent better performance when compared to traditional hydrazine. Photo Credit: (NASA/Carla Cioffi)

Attitudes and Perceptions of Vocational Education in New York City: Implications for the Mayor's School Reform Initiative

ERIC Educational Resources Information Center

Green, Rupert

2012-01-01

Under-performing New York City (NYC) schools precipitated Mayor Michael Bloomberg's decision to advance a vocational education initiative. The initiative was to address the problem of the many city high school graduates lacking both the skills for gainful employment and the academic preparedness to pursue higher education. The mayor's initiative…

Without the Light of Evolution: A Case Study of Resistance and Avoidance in Learning to Teach High School Biology

ERIC Educational Resources Information Center

Larkin, Douglas B.; Perry-Ryder, Gail M.

2015-01-01

We present the case of Michael, a prospective high school biology teacher, to explore the implications of teacher resistance and avoidance to the topic of evolution. This case is drawn from a year-long qualitative research study that examined Michael's process of learning to teach high school biology and describes how his avoidance of evolution in…

Production of Low-Freezing-Point Highly Branched Alkanes through Michael Addition.

PubMed

Jing, Yaxuan; Xia, Qineng; Liu, Xiaohui; Wang, Yanqin

2017-12-22

A new approach for the production of low-freezing-point, high-quality fuels from lignocellulose-derived molecules was developed with Michael addition as the key step. Among the investigated catalysts, CoCl 2 ⋅6 H 2 O was found most active for the Michael addition of 2,4-pentanedione with FA (single aldol adduct of furfural and acetone, 4-(2-furanyl)-3-butene-2-one). Over CoCl 2 ⋅6 H 2 O, a high carbon yield of C 13 oxygenates (about 75 %) can be achieved under mild conditions (353 K, 20 h). After hydrodeoxygenation, low-freezing-point (<223 K) branched alkanes with 13 carbons within jet fuel ranges were obtained over a Pd/NbOPO 4 catalyst. Furthermore, C 18,23 fuel precursors could be easily synthesized through Michael addition of 2,4-pentanedione with DFA (double-condensation product of furfural and acetone) under mild conditions and the molar ratio of C 18 /C 23 is dependent on the reaction conditions of Michael addition. After hydrodeoxygenation, high density (0.8415 g mL -1 ) and low-freezing-point (<223 K) branched alkanes with 18, 23 carbons within lubricant range were also obtained over a Pd/NbOPO 4 catalyst. These highly branched alkanes can be directly used as transportation fuels or additives. This work opens a new strategy for the synthesis of highly branched alkanes with low freezing point from renewable biomass. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Neuroscientific Investigator of High Mathematical Ability: An Interview with Michael W. O'Boyle

ERIC Educational Resources Information Center

Kalbfleisch, M. Layne

2008-01-01

This article presents an interview with Michael W. O'Boyle, a neuroscientific investigator of high mathematical ability. O'Boyle is a professor in the Department of Human Development and Family Studies, Texas Tech University, and Adjunct Professor of Pharmacology and Neuroscience, School of Medicine, Texas Tech University Health Sciences Center.…

Dr. Michael DeBakey "is a magician of the heart…"

MedlinePlus

... Dr. DeBakey with NLM's David Nash and admiring students from the Michael E. DeBakey High School for ... medical research as the means of discovering improved methods of diagnosis, treatment, prevention, and cure. As far ...

Defense Innovation Unit Experimental (DIUX): Innovative or Excessive

DTIC Science & Technology

2017-04-06

DIUx, and the short history of DIUx. Innovation principles from authors Vijay Govindarajan, Michael Docherty, and Clayton Christensen are then...innovation principles such as performance engine & innovative team, collective / open innovation, and disruptive technology and its implications – is...various innovation principles drawing primarily from work by authors Vijay Govindarajan and Chris Trimble, Michael Docherty, and Clayton Christenson

Performance Enhancement of the NPS Transient Electromagnetic Scattering Laboratory

DTIC Science & Technology

1991-09-01

MASTER OF SCIENCE IN ELECTRICAL ENGINEERING MASTER OF SCIENCE IN SYSTEMS ENGINEERING (ELECTRONIC WARFARE) from NAVAL POSTGRADUATE S OOL Author: JvAlo...Bresani Approved by: Michael A. Morgan, Thesis Advisor Jeffrey B. Knorr, Second Reader Michael A. Morgan, Chairman, Department of Electrical & Computer...SYSTEM REPRESENTATION ... .......... 13 B. MATHEMATICAL MODEL ......... ..... 15 C. TRANSIENT RESPONSE EVALUATION .. ......... . 17 IV. MEASUREMENT

Highly convergent synthesis of chiral bicyclophosphinates by domino hydrophosphinylation/Michael/Michael reaction.

PubMed

Fourgeaud, Pierre; Daydé, Bénédicte; Volle, Jean-Noël; Vors, Jean-Pierre; Van der Lee, Arie; Pirat, Jean-Luc; Virieux, David

2011-10-07

Diastereoselective domino reactions of iminoalcohols and allenyl H-phosphinates produce chiral phosphorus bicycles in a regio- and stereoselective fashion. A predictive model for diastereoselection is used for these new chiral phosphinic esters. © 2011 American Chemical Society

Organocatalytic asymmetric anti-selective Michael reactions of aldehydes and the sequential reduction/lactonization/Pauson-Khand reaction for the enantioselective synthesis of highly functionalized hydropentalenes.

PubMed

Hong, Bor-Cherng; Dange, Nitin S; Yen, Po-Jen; Lee, Gene-Hsiang; Liao, Ju-Hsiou

2012-10-19

A new method has been developed for the enantioselective synthesis of highly functionalized hydropentalenes bearing up to four stereogenic centers with high stereoselectivity (up to 99% ee). This process combines an enantioselective organocatalytic anti-selective Michael addition with a highly efficient one-pot reduction/lactonization/Pauson-Khand reaction sequence. The structures and absolute configurations of the products were confirmed by X-ray analysis.

Racemic hemiacetals as oxygen-centered pronucleophiles triggering cascade 1,4-addition/Michael reaction through dynamic kinetic resolution under iminium catalysis. Development and mechanistic insights† †Electronic supplementary information (ESI) available: Detailed experimental procedures and characterization of all new compounds, including copies of NMR spectra and HPLC chromatograms traces, computational details and Cartesian coordinates of all stationary points. CCDC 1525188 (4l), 1525189 (6a) and 1525190 (9a). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc00009j Click here for additional data file. Click here for additional data file.

PubMed Central

Orue, Ane; Uria, Uxue; Roca-López, David; Delso, Ignacio; Reyes, Efraím; Carrillo, Luisa

2017-01-01

2-Hydroxydihydropyran-5-ones behave as excellent polyfunctional reagents able to react with enals through oxa-Michael/Michael process cascade under the combination of iminium and enamine catalysis. These racemic hemiacetalic compounds are used as unconventional O-pronucleophiles in the initial oxa-Michael reaction, also leading to the formation of a single stereoisomer under a dynamic kinetic resolution (DKR) process. Importantly, by using β-aryl or β-alkyl substituted α,β-unsaturated substrates as initial Michael acceptors either kinetically or thermodynamically controlled diastereoisomers were formed with high stereoselection through the careful selection of the reaction conditions. Finally, a complete experimental and computational study confirmed the initially proposed DKR process during the catalytic oxa-Michael/Michael cascade reaction and also explained the kinetic/thermodynamic pathway operating in each case. PMID:28451356

High-Resolution Seismic Velocity and Attenuation Models of the Caucasus-Caspian Region

DTIC Science & Technology

2008-09-30

Skobeltsyn, 1010 Ugur Teoman , Tea Godoladze’, and Eric Sandvol’ 5e. TASK NUMBERSM 5f. WORK UNIT NUMBER Al 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS...CASPIAN REGION Robert Mellors’, Rengin G6k2 , Michael Pasyanos 2, Gleb Skobeltsyn 3, Ugur Teoman4, Tea Godoladze 5 , and Eric Sandvol 3 San Diego

Pyrrolidinyl-camphor derivatives as a new class of organocatalyst for direct asymmetric Michael addition of aldehydes and ketones to beta-nitroalkenes.

PubMed

Ting, Ying-Fang; Chang, Chihliang; Reddy, Raju Jannapu; Magar, Dhananjay R; Chen, Kwunmin

2010-06-18

Practical and convenient synthetic routes have been developed for the synthesis of a new class of pyrrolidinyl-camphor derivatives (7 a-h). These novel compounds were screened as catalysts for the direct Michael addition of symmetrical alpha,alpha-disubstituted aldehydes to beta-nitroalkenes. When this asymmetric transformation was catalyzed by organocatalyst 7 f, the desired Michael adducts were obtained in high chemical yields, with high to excellent stereoselectivities (up to 98:2 diastereomeric ratio (d.r.) and 99 % enantiomeric excess (ee)). The scope of the catalytic system was expanded to encompass various aldehydes and ketones as the donor sources. The synthetic application was demonstrated by the synthesis of a tetrasubstituted-cyclohexane derivative from (S)-citronellal, with high stereoselectivity.

Thin Film Thermoelectric Metal-Organic Framework with High Seebeck Coefficient and Low Thermal Conductivity. Supporting Information

DTIC Science & Technology

2015-04-28

François Léonard, Vitalie Stavila, Michael E. Foster, Catalin D. Spataru, Reese E. Jones, Brian M. Foley, Patrick E. Hopkins, Mark D. Allendorf, A. Alec...Léonard, Vitalie Stavila, Michael E. Foster, Catalin D. Spataru, Reese E. Jones, Brian M. Foley, Patrick E. Hopkins, Mark D. Allendorf, and A. Alec Talin...Kristopher J. Erickson, François Léonard, Vitalie Stavila, Michael E. Foster, Catalin D. Spataru, Reese E. Jones, Brian M. Foley, Patrick E. Hopkins, Mark D

Synthesis of pyroglutamic acid derivatives via double michael reactions of alkynones.

PubMed

Scansetti, Myriam; Hu, Xiangping; McDermott, Benjamin P; Lam, Hon Wai

2007-05-24

In the presence of substoichiometric quantities of potassium tert-butoxide and an additional metal salt, amide-tethered diacids undergo double Michael reactions with alkynones to provide highly functionalized pyroglutamic acid derivatives. The metal salt was found to play an important role in improving the diastereoselectivities of the reactions.

Employment programs and professionals with a disability.

PubMed

Donelly, Michelle; Given, Fiona

2010-01-01

It is unclear whether or not open (competitive) employment programs are meeting the needs of the growing numbers of people with a disability seeking professional employment. To understand and describe the experience of a newly graduated professional (Michael) who was seeking open employment support and to analyze those experiences in relation to principles of effective open employment support. Michael a recently graduated accountant who also has a physical disability. A review of the literature was undertaken to identify recommended principles and practices for the conduct of effective open employment and career development programs. A case study was used to describe Michael's experiences as he sought professional employment. Michael's experiences were analysed in relation to recommended principles and practice. The analysis confirmed that the concerns Michael experienced about the supported employment program compromised the effectiveness of the support he received. Employment services based on models of independent living, disability service standards and remediation are likely to focus on the 'pathology' or performance 'deficits' of the person with a disability. Successful open employment models are more likely to place pre-eminence on the perspective of the person with a disability and effective practices for securing employment.

Trading Freshness for Performance in Distributed Systems

DTIC Science & Technology

2014-12-01

Systems (IOPADS ’99), May 1999. 3.6 Charles Babcock. Data, data, everywhere. Information Week, January 2006. 3.2 Peter Bailis, Shivaram Venkataraman ... Venkataraman , Michael J. Franklin, Joseph M. Hellerstein, and Ion Stoica. Pbs at work: Advancing data management with consistency metrics. In Proceedings of...5. doi: 10.1145/2463676.2465260. URL http://doi.acm.org/10. 1145/2463676.2465260. 2.4 Peter Bailis, Shivaram Venkataraman , Michael J. Franklin, Joseph

Generation of Tutorial Dialogues: Discourse Strategies for Active Learning

DTIC Science & Technology

1998-05-29

AND SUBTITLE Generation of Tutorial Dialogues: Discourse Strategies for active Learning AUTHORS Dr. Martha Evens 7. PERFORMING ORGANI2ATION NAME...time the student starts in on a new topic. Michael and Rovick constantly attempt to promote active learning . They regularly use hints and only resort...Controlling active learning : How tutors decide when to generate hints. Proceedings of FLAIRS 󈨣. Melbourne Beach, FL. 157-161. Hume, G., Michael

Organocatalytic aza-Michael/retro-aza-Michael reaction: pronounced chirality amplification in aza-Michael reaction and racemization via retro-aza-Michael reaction.

PubMed

Cai, Yong-Feng; Li, Li; Luo, Meng-Xian; Yang, Ke-Fang; Lai, Guo-Qiao; Jiang, Jian-Xiong; Xu, Li-Wen

2011-05-01

A detailed experimental investigation of an aza-Michael reaction of aniline and chalcone is presented. A series of Cinchona alkaloid-derived organocatalysts with different functional groups were prepared and used in the aza-Michael and retro-aza-Michael reaction. There was an interesting finding that a complete reversal of stereoselectivity when a benzoyl group was introduced to the cinchonine and cinchonidine. The chirality amplification vs. time proceeds in the quinine-derived organocatalyst containing silicon-based bulky group, QN-TBS, -catalyzed aza-Michael reaction under solvent-free conditions. In addition, we have demonstrated for the first time that racemization was occurred in suitable solvents under mild conditions due to retro-aza-Michael reaction of the Michael adduct of aniline with chalcone. These indicate the equilibrium of retro-aza-Michael reaction and aza-Michael reaction produce the happening of chirality amplification in aza-Michael reaction and racemization via retro-aza-Michael reaction under different conditions, which would be beneficial to the development of novel chiral catalysts for the aza-Michael reactions. Copyright © 2011 Wiley-Liss, Inc.

STS-113 Post Flight Presentation

NASA Astrophysics Data System (ADS)

2002-01-01

The STS-113 post-flight presentation begins with a view of Mission Specialists Michael E. Lopez-Alegria and John B. Herrington getting suited for the space mission. The STS-113 crew consists of: Commander James D. Wetherbee, Pilot Paul Lockhart, Mission Specialists Michael Lopez-Alegria and John Herrington. Cosmonauts Valery Korzun, and Sergei Treschev, and astronaut Peggy Whitson who are all members of the expedition five crew, and Commander Kenneth Bowersox, Flight Engineers Nikolai Budarin and Donald Pettit, members of Expedition Six. The main goal of this mission is to take Expedition Six up to the International Space Station and Return Expedition Five to the Earth. The second objective is to install the P(1) Truss segment. Three hours prior to launch, the crew of Expedition Six along with James Wetherbee, Paul Lockhart, Michael Lopez-Alegria and John Herrington are shown walking to an astrovan, which takes them to the launch pad. The actual liftoff is presented. Three Extravehicular Activities (EVA)'s are performed on this mission. Michael Lopez-Alegria and John Herrington are shown performing EVA 1 and EVA 2 which include making connections between the P1 and S(0) Truss segments, and installing fluid jumpers. A panoramic view of the ISS with the Earth in the background is shown. The grand ceremony of the crew exchange is presented. The astronauts performing everyday duties such as brushing teeth, washing hair, sleeping, and eating pistachio nuts are shown. The actual landing of the Space Shuttle is presented.

Acid-Activatable Michael-Type Fluorescent Probes for Thiols and for Labeling Lysosomes in Live Cells.

PubMed

Dai, Chun-Guang; Du, Xiao-Jiao; Song, Qin-Hua

2015-12-18

A Michael addition is usually taken as a base-catalyzed reaction. Most fluorescent probes have been designed to detect thiols in slightly alkaline solutions (pH 7-9). The sensing reactions of almost all Michael-type fluorescent probes for thiols are faster in a high pH solution than in a low pH solution. In this work, we synthesized a series of 7-substituted 2-(quinolin-2-ylmethylene)malonic acids (QMAs, substituents: NEt2, OH, H, Cl, or NO2) and their ethyl esters (QMEs) as Michael-type fluorescent probes for thiols. The sensing reactions of QMAs and QMEs occur in distinct pH ranges, pH < 7 for QMAs and pH > 7 for QMEs. On the basis of experimental and theoretic studies, we have clarified the distinct pH effects on the sensing reactivity between QMAs and QMEs and demonstrated that two QMAs (NEt2, OH) are highly sensitive and selective fluorescent probes for thiols in acidic solutions (pH < 7) and promising dyes that can label lysosomes in live cells.

Water-Based Coating Simplifies Circuit Board Manufacturing

NASA Technical Reports Server (NTRS)

2008-01-01

The Structures and Materials Division at Glenn Research Center is devoted to developing advanced, high-temperature materials and processes for future aerospace propulsion and power generation systems. The Polymers Branch falls under this division, and it is involved in the development of high-performance materials, including polymers for high-temperature polymer matrix composites; nanocomposites for both high- and low-temperature applications; durable aerogels; purification and functionalization of carbon nanotubes and their use in composites; computational modeling of materials and biological systems and processes; and developing polymer-derived molecular sensors. Essentially, this branch creates high-performance materials to reduce the weight and boost performance of components for space missions and aircraft engine components. Under the leadership of chemical engineer, Dr. Michael Meador, the Polymers Branch boasts world-class laboratories, composite manufacturing facilities, testing stations, and some of the best scientists in the field.

Michael Deru | NREL

Science.gov Websites

development and testing of novel HVAC systems, building performance simulations, performance metrics for | 303-384-7503 Dr. Deru joined NREL in 2000 and manages the Systems Performance section in the

Biography for Michael Rossol | NREL

Science.gov Websites

Biography for Michael Rossol Michael Rossol Michael Rossol Resource Data Scientist Michael.Rossol @nrel.gov | 303-275-3680 Michael Rossol is a member of the Systems Modeling team within the Systems Modeling

Using Heart Rate to Predict Resilience and Susceptibility to PTSD in Soldiers

DTIC Science & Technology

2011-04-01

Predict Resilience and Susceptibility to PTSD in Soldiers Authors Brian Chung Jonathan Lanier Lolita M. Burrell Michael D. Matthews...AUTHOR(S) Brian Chung; Jonathan Lanier; Lolita Burrell; Michael Matthews 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING...members of the control group were matched with one of the trauma or PTSD victims based on age and sex and both individuals were shown the same

2016 Summer Series - Michael Flynn - Synthetic Biological Membrane

NASA Image and Video Library

2016-08-02

Full understanding leads to creation capability, which results in customization capacity. Synthetic biology uses our knowledge of biology to engineer novel biological devices or organisms that can perform tasks not found in nature. For Human space exploration, synthetic biology approaches will reduce risk, mass carried and increase Human reach. Michael Flynn will discuss the International Space Station (ISS) water recycling and his current work on developing a water filtration system capable of self-repair.

The Role of Data and Feedback Error in Inference and Prediction

DTIC Science & Technology

1998-06-01

O’Connor Bowling Green State University Research and Advanced Concepts Office Michael Drillings, Chief This Document Contains Missing Page/s...Bowling Green State University Technical Review by Michael Drillings, ARI NOTICES DISTRIBUTION: This Research Note has been cleared for release to...0601102A 2O161102B74F TA 1012 WU C06 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Bowling Green State University , 120 Mcfall Center, Research

Flexural and Tensile Properties of Thin, Very High-Strength, Fiber-Reinforced Concrete Panels

DTIC Science & Technology

2008-09-01

Fiber - Reinforced Concrete Panels Michael J. Roth September 2008 G eo te ch ni ca l a nd S tr uc tu re s La bo ra to ry Approved for...Tensile Properties of Thin, Very High-Strength, Fiber - Reinforced Concrete Panels Michael J. Roth Geotechnical and Structures Laboratory U.S. Army...of Michigan, Ann Arbor, and noted authority in the field of 160 fiber - reinforced concrete . Implementation of Li’s work

Design of an Advanced Modular Automated Evaluation System for Experimental High Power SGTOS

DTIC Science & Technology

2013-06-01

POWER SGTOS Shelby Lacouture, Kevin Lawson, Stephen Bayne, Michael Giesselmann, Heather O’Brien 1 , Aderinto Ogunniyi 1 , Charles J...Travis T. Vollmer and Michael G. Giesselmann, Rapid Capacitor Charging Power Supply for an 1800J PFN, Proceedings of the 2012 Power Modulator and High Voltage Conference, San Diego, CA, June 3-7, 2012. 1023 ...Scozzie 1 Center for Pulsed Power and Power Electronics Department of Electrical & Computer Engineering Texas Tech

Efficient synthesis of optically active 4-nitro-cyclohexanones via bifunctional thiourea-base catalyzed double-Michael addition of nitromethane to dienones.

PubMed

Wu, Bin; Liu, Guo-Gui; Li, Mei-Qiu; Zhang, Yong; Zhang, Shao-Yun; Qiu, Jun-Ru; Xu, Xiao-Ping; Ji, Shun-Jun; Wang, Xing-Wang

2011-04-07

Thiourea-modified cinchona alkaloids as bifunctional catalysts and a base could catalyze a stepwise [5+1] cyclization of divinyl ketones with nitromethane via double Michael additions, furnishing optically active 4-nitro-cyclohexanones with good yields, excellent diastereoselectivities (>20 : 1) and high enantiomeric ratios (up to 97 : 3).

An improved procedure to prepare 3-methyl-4-nitroalkylenethylisoxazoles and their reaction under catalytic enantioselective Michael addition with nitromethane.

PubMed

Moccia, Maria; Wells, Robert J; Adamo, Mauro F A

2015-02-21

Herein, we describe a short synthesis of 3-methyl-4-nitro-5-alkylethenyl isoxazoles and their reactivity as Michael acceptors. The title compounds reacted with nitromethane under phase-transfer catalysis to provide highly enantioenriched adducts (up to 93% ee) which were then converted to the corresponding γ-nitroacids.

On Happiness and High Achievement: An Interview with Michael Thompson

ERIC Educational Resources Information Center

National Association of Independent Schools (NAIS) (NJ), 2006

2006-01-01

Michael G. Thompson knows independent schools. He attended them in elementary and secondary school, and has worked in them as a psychologist. He consults with more than 30 schools a year, addressing a myriad of issues related to complex human interaction. He has written often in "Independent School" about everything from understanding the social…

An Interview with Michael Horn: Blending Education for High-Octane Motivation

ERIC Educational Resources Information Center

Patterson, Gregory A.

2012-01-01

Blended learning holds the potential of improving the way we educate students and of making them more motivated. Blended education--the melding of information technology based distance learning with school attendance--is perhaps the best way to educate students for 21st century skills, says Michael Horn in a "Kappan" interview. Horn points out…

Gold (III) Chloride-Catalyzed 6-endo-trig Oxa-Michael Addition Reactions for Diastereoselective Synthesis of Fused Tetrahydropyranones

PubMed Central

Ciesielski, Jennifer; Lebœuf, David; Stern, Harry A.

2013-01-01

Alkynones were treated with boron trifluoride diethyl etherate to generate β-iodoallenolates, which underwent intramolecular aldol reactions to produce cycloalkenyl alcohols. Diastereoselective oxa-Michael ring closure could then be induced by treatment with a catalytic amount of gold(III) chloride, affording highly functionalized tetrahydropyran-containing ring systems. PMID:24032002

Asymmetric Michael Addition Mediated by Chiral Ionic Liquids.

PubMed

Suzuki, Yumiko

2018-06-01

Chiral ionic liquids with a focus on their applications in asymmetric Michael additions and related reactions were reviewed. The examples were classified on the basis of the mode of asymmetric induction (e.g., external induction/non-covalent interaction or internal induction/covalent bond formation), the roles in reactions (as a solvent or catalyst), and their structural features (e.g., imidazolium-based chiral cations, other chiral oniums; proline derivatives). Most of the reactions with high chiral induction are Michael addition of ketones or aldehydes to chalcones or nitrostyrenes where proline-derived chiral ionic liquids catalyze the reaction through enamine/ iminium formation. Many reports demonstrate the recyclability of ionic liquid-tagged pyrrolidines.

Ablative Heat Shield Studies for NASA Mars/Earth Return Entry Vehicles

DTIC Science & Technology

1990-09-01

RETURN ENTRY VEHICLES by Michael K. Hamm September, 1990 NASA Thesis Advisor: William D. Henline Thesis Co-Advisor: Max F. Platzer Approved for public...STUDIES FOR NASA MARS/EARTH RETURN ENTRY VEHICLES (UNCLASSIFIED) 12. PERSONAL AUTHOR(S) Harm, Michael, K. 13a TYPE OF REPORT 13b TIME COVERED 14 DATE OF...theoretical values. The tests were performed to ascertain if RSI type materials could be used for entry vehicles proposed in NASA Mars missions. 20

Advancement and Application of Multi-Phase CFD Modeling to High Speed Supercavitating Flows

DTIC Science & Technology

2013-08-13

5a. CONTRACT NUMBER 5b. GRANT NUMBER N00014-09-1-0042 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Jules W. Lindau and Michael P. Kinzel 5d. PROJECT...REPORT U b. ABSTRACT U c. THIS PAGE U 17. LIMITATION OF ABSTRACT U 18. NUMBER OF PAGES 29 19a. NAME OF RESPONSIBLE PERSON Jules W. Lindau...Application of Multi-Phase CFD Modeling to High Speed Supercavitating Flows Michael P. Kinzel Jules W. Lindau Penn State University Applied Research

Automated synthesis of a library of triazolated 1,2,5-thiadiazepane 1,1-dioxides via a double aza-Michael strategy.

PubMed

Zang, Qin; Javed, Salim; Hill, David; Ullah, Farman; Bi, Danse; Porubsky, Patrick; Neuenswander, Benjamin; Lushington, Gerald H; Santini, Conrad; Organ, Michael G; Hanson, Paul R

2012-08-13

The construction of a 96-member library of triazolated 1,2,5-thiadiazepane 1,1-dioxides was performed on a Chemspeed Accelerator (SLT-100) automated parallel synthesis platform, culminating in the successful preparation of 94 out of 96 possible products. The key step, a one-pot, sequential elimination, double-aza-Michael reaction, and [3 + 2] Huisgen cycloaddition pathway has been automated and utilized in the production of two sets of triazolated sultam products.

Automated Synthesis of a Library of Triazolated 1,2,5-Thiadiazepane 1,1-Dioxides via a Double aza-Michael Strategy

PubMed Central

Zang, Qin; Javed, Salim; Hill, David; Ullah, Farman; Bi, Danse; Porubsky, Patrick; Neuenswander, Benjamin; Lushington, Gerald H.; Santini, Conrad; Organ, Michael G.; Hanson, Paul R.

2013-01-01

The construction of a 96-member library of triazolated 1,2,5-thiadiazepane 1,1-dioxides was performed on a Chemspeed Accelerator (SLT-100) automated parallel synthesis platform, culminating in the successful preparation of 94 out of 96 possible products. The key step, a one-pot, sequential elimination, double-aza-Michael reaction, and [3+2] Huisgen cycloaddition pathway has been automated and utilized in the production of two sets of triazolated sultam products. PMID:22853708

Asymmetric Michael Addition Mediated by Chiral Ionic Liquids

PubMed Central

Suzuki, Yumiko

2018-01-01

Chiral ionic liquids with a focus on their applications in asymmetric Michael additions and related reactions were reviewed. The examples were classified on the basis of the mode of asymmetric induction (e.g., external induction/non-covalent interaction or internal induction/covalent bond formation), the roles in reactions (as a solvent or catalyst), and their structural features (e.g., imidazolium-based chiral cations, other chiral oniums; proline derivatives). Most of the reactions with high chiral induction are Michael addition of ketones or aldehydes to chalcones or nitrostyrenes where proline-derived chiral ionic liquids catalyze the reaction through enamine/ iminium formation. Many reports demonstrate the recyclability of ionic liquid-tagged pyrrolidines. PMID:29861702

Textbooks, Teachers and Full-Colour Vision: Some Thoughts on Evaluating Environmental Education "Performance".

ERIC Educational Resources Information Center

Courtenay-Hall, Pamela

1998-01-01

Discusses the problem of environmental bias and critiques Michael Sanera's approach to evaluation of environmental education performance. Notes that problems result from bias in curriculum materials. Contains 20 references. (DDR)

A facile and efficient method of enzyme immobilization on silica particles via Michael acceptor film coatings: immobilized catalase in a plug flow reactor.

PubMed

Bayramoglu, Gulay; Arica, M Yakup; Genc, Aysenur; Ozalp, V Cengiz; Ince, Ahmet; Bicak, Niyazi

2016-06-01

A novel method was developed for facile immobilization of enzymes on silica surfaces. Herein, we describe a single-step strategy for generating of reactive double bonds capable of Michael addition on the surfaces of silica particles. This method was based on reactive thin film generation on the surfaces by heating of impregnated self-curable polymer, alpha-morpholine substituted poly(vinyl methyl ketone) p(VMK). The generated double bonds were demonstrated to be an efficient way for rapid incorporation of enzymes via Michael addition. Catalase was used as model enzyme in order to test the effect of immobilization methodology by the reactive film surface through Michael addition reaction. Finally, a plug flow type immobilized enzyme reactor was employed to estimate decomposition rate of hydrogen peroxide. The highly stable enzyme reactor could operate continuously for 120 h at 30 °C with only a loss of about 36 % of its initial activity.

Organocatalytic Enantioselective Michael/Cyclization Domino Reaction between 3-Amideoxindoles and α,β-Unsaturated Aldehydes: One-Pot Preparation of Chiral Spirocyclic Oxindole-γ-lactams.

PubMed

Yang, Peng; Wang, Xiao; Chen, Feng; Zhang, Zheng-Bing; Chen, Chao; Peng, Lin; Wang, Li-Xin

2017-04-07

The first organocatalytic enantioselective Michael/cyclization domino reaction between 3-amideoxindoles and α,β-unsaturated aldehydes is described. After sequential oxidation with pyridinium chlorochromate, a direct and one-pot preparation of highly sterically hindered spirocyclic oxindole-γ-lactams was achieved in 51-81% yields with 75-97% ee and ≤80/20 dr.

High performance bio-based thermosets for composites and coatings

NASA Astrophysics Data System (ADS)

Paramarta, Adlina Ambeg

In the recent decade, there has been increasing interest in using renewable feedstocks as chemical commodities for composites and coatings application. Vegetable oils are promising renewable resources due to their wide availability with affordable cost. In fact, the utilization of vegetable oils to produce composite and coatings products has been around for centuries; linseed oil was widely used for wide variety of paints. However, due to its chemical structure, the application of vegetable oils for high-performance materials is limited; and thus chemical modification is necessary. One of the modification approaches is by substituting the glycerol core in the triglycerides with sucrose to form sucrose esters of vegetable oil fatty acids, in which this resin possesses a higher number of functional group per molecule and a more rigid core. In this research, thermosets of highly functionalized sucrose esters of vegetable oils were developed. Two crosslinking methods of epoxidized surcrose soyate (ESS) resins were explored: direct polymerization with anhydride moieties for composite applications and Michael-addition reaction of acrylated-epoxidized sucrose soyate (AESS) for coatings applications. In the first project, it was shown that the reaction kinetics, thermal and mechanical properties of the materials can be tuned by varying the molar ratio between the epoxide and anhydride, plus the type and amount of catalyst. Furthermore, the toughness properties of the ESS-based thermosets can be improved by changing the type of anhydride crosslinkers and incorporating secondary phase rubbers. Then, in the second system, the epoxy functionality in the ESS was converted into acrylate group, which then crosslinked with amine groups through the Michael-addition reaction to produce coatings systems. The high number of functional groups and the fast reactivity of the crosslinker results in coatings that can be cured at ambient temperature, yet still possess moderately high glass transition temperatures.

Metafile for Interactive Documents. Version 2.0. Application Guide and Draft Performance Specification for the Encoding of Interactive Documents.

DTIC Science & Technology

1996-03-01

Darlene Janiszewski, NAWC-AD, Project Manager L. John Junod , NSWC-CD Michael Anderson, Antech Systems, Editor and Team Chairman David Cooper, Antech...Michael Croswell, CSC Mark Drissel, CSC Rob Groat, Booz Allen Eric Jorgensen, NSWC Carderock L. John Junod , NSWC Carderock Neill Kipp, TechnoTeacher Steve...contact Mr. John Junod at < junod @oasys.dt.navy.mil>. 1 MID-2 (3/96) 2.2.3 MID Design & Development Team Members The MID Design Team was formed in

2nd EVA - MS Foale and Nicollier during FGS changeout

NASA Image and Video Library

1999-12-24

STS103-501-026 (19 - 27 December 1999) --- Astronauts C. Michael Foale, left, and Claude Nicollier (on Discovery's robotic arm) install a Fine Guidance Sensor (FGS) into a protective enclosure in the Shuttle’s payload bay. Foale and Nicollier performed the second of three space walks to service the Hubble Space Telescope (HST) on the STS-103 mission. A large format camera inside Discovery's cabin was used to record this high-resolution image, while the Shuttle was orbiting above ocean and clouds.

Michael Deceglie | NREL

Science.gov Websites

postdoctoral researcher focused on photovoltaic performance and reliability. His current research interests illumination nonuniformity, and outdoor performance of advanced photovoltaic technologies. Featured photovoltaic module," Proceedings of the Thirty-ninth IEEE Photovoltaic Specialists Conference (PVSC), pp

Acquisition Review Quarterly (ARQ): Volume 10, Number 3, Summer 2003

DTIC Science & Technology

2003-01-01

PROJECT NUMBER Lt Col Robert L. Waller, USAF, (Ret), Robert Graham, Maj David R. King, USAF, Lt Col John D. Driessnack, USAF, LTC Michael D. Proctor...High-Technology Industries Implications for Industrial Policy Maj David R. King, USAF Lt Col John D. Driessnack, USAF Why the "T" in SMART A...Business School William H . Reed Director Michael Wynne Defense Contract Audit Agency Acting Under Secretary of Defense (Acquisition, Technology, and

Part 3. a novel stereocontrolled, in situ, solution- and solid-phase, Aza Michael approach for high-throughput generation of tetrahydroaminoquinoline-derived natural-product-like architectures.

PubMed

Prakesch, Michael; Srivastava, Stuti; Leek, Donald M; Arya, Prabhat

2006-01-01

With the goal of rapidly accessing tetrahydroquinoline-based natural-product-like polycyclic architectures, herein, we report an unprecedented, in situ, stereocontrolled Aza Michael approach in solution and on the solid phase. The mild reaction conditions required to reach the desired target are highly attractive for the use of this method in library generation. To our knowledge, this approach has not been used before, and it opens a novel route leading to a wide variety of tetrahydroquinoline-derived bridged tricyclic derivatives.

Theoretical study on the reaction mechanisms of Michael chirality addition between propionaldehyde and nitroalkene catalyzed by an enantioselective catalyst.

PubMed

Zhou, Xinming; Li, Ling; Sun, Xuejun; Wang, Yajun; Du, Dongmei; Fu, Hui

2018-06-01

The asymmetric Michael addition between propionaldehyde and nitroalkene catalyzed by 8-(ethoxycarbonyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole-2-carboxylic acid has obtained relatively high yields and excellent enantioselectivities at room temperature. In this study, the molecular structures and optical activity of the most stable conformation I are optimized at B3LYP/6-311++ G(d,p) level. We find that levorotatory conformation I catalyzing the same Michael addition can produce laevo-product A and dextrorotatory conformation I' can obtain the dextral-product A'. These results have guiding significance for further studying on the new chemzymes and the mechanism of the obtained different chiral products. © 2018 Wiley Periodicals, Inc.

Combining silver catalysis and organocatalysis: a sequential Michael addition/hydroalkoxylation one-pot approach to annulated coumarins.

PubMed

Hack, Daniel; Chauhan, Pankaj; Deckers, Kristina; Hermann, Gary N; Mertens, Lucas; Raabe, Gerhard; Enders, Dieter

2014-10-03

A highly stereoselective one-pot procedure for the synthesis of five-membered annulated hydroxycoumarins has been developed. By merging primary amine catalysis with silver catalysis, a series of functionalized coumarin derivatives were obtained in good yields (up to 91%) and good to excellent enantioselectivities (up to 99% ee) via a Michael addition/hydroalkoxylation reaction. Depending on the substituents on the enynone, the synthesis of annulated six-membered rings is also feasible.

The power of virtual integration: an interview with Dell Computer's Michael Dell. Interview by Joan Magretta.

PubMed

Dell, M

1998-01-01

Michael Dell started his computer company in 1984 with a simple business insight. He could bypass the dealer channel through which personal computers were then being sold and sell directly to customers, building products to order. Dell's direct model eliminated the dealer's markup and the risks associated with carrying large inventories of finished goods. In this interview, Michael Dell provides a detailed description of how his company is pushing that business model one step further, toward what he calls virtual integration. Dell is using technology and information to blur the traditional boundaries in the value chain between suppliers, manufacturers, and customers. The individual pieces of Dell's strategy--customer focus, supplier partnerships, mass customization, just-in-time manufacturing--may be all be familiar. But Michael Dell's business insight into how to combine them is highly innovative. Direct relationships with customers create valuable information, which in turn allows the company to coordinate its entire value chain back through manufacturing to product design. Dell describes how his company has come to achieve this tight coordination without the "drag effect" of ownership. Dell reaps the advantages of being vertically integrated without incurring the costs, all the while achieving the focus, agility, and speed of a virtual organization. As envisioned by Michael Dell, virtual integration may well become a new organizational model for the information age.

Michael Addition Reactions between Chiral Equivalents of a Nucleophilic Glycine and (S)- or (R)-3-[(E)-Enoyl]-4-phenyl-1,3-oxazolidin-2-ones as a General Method for Efficient Preparation of β-Substituted Pyroglutamic Acids. Case of Topographically Controlled Stereoselectivity

PubMed Central

Soloshonok*, Vadim A.; Cai, Chaozhong; Yamada, Takeshi; Ueki, Hisanori; Ohfune, Yasufumi; Hruby, Victor J.

2006-01-01

This paper describes a systematic study of addition reactions between the chiral Ni(II) complex of the Schiff base of glycine with (S)-o-[N-(N-benzylprolyl)amino]benzophenone and (S)- or (R)-3-[(E)-enoyl]-4-phenyl-1,3-oxazolidin-2-ones as a general and synthetically efficient approach to β-substituted pyroglutamic acids and relevant compounds. These reactions were shown to occur at room temperature in the presence of nonchelating organic bases and, most notably, with very high (>98% diastereomeric excess (de)) stereoselectivity at both newly formed stereogenic centers. The stereochemical outcome of the reactions was found to be overwhelmingly controlled by the stereochemical preferences of the Michael acceptors, and the chirality of the glycine complex influenced only the reaction rate. Thus, in the reactions of both the (S)-configured Ni(II) complex and the Michael acceptors, the reaction rates were exceptionally high, allowing preparation of the corresponding products with virtually quantitative (>98%) chemical and stereochemical yields. In contrast, reactions of the (S)-configured Ni(II) complex and (R)-configured Michael acceptors proceeded at noticeably lower rates, but the addition products were obtained in high diastereo-and enantiomeric purity. To rationalize the remarkably high and robust stereoselectivity observed in these reactions, we consider an enzyme–substrate-like mode of interaction involing a topographical match or mismatch of two geometric figures. Excellent chemical and stereochemical yields, combined with the simplicity and operational convenience of the experimental procedures, render the present method of immediate use for preparing various β-substituted pyroglutamic acids and related compounds. PMID:16248672

Michael addition reactions between chiral equivalents of a nucleophilic glycine and (S)- or (R)-3-[(E)-enoyl]-4-phenyl-1,3-oxazolidin-2-ones as a general method for efficient preparation of beta-substituted pyroglutamic acids. Case of topographically controlled stereoselectivity.

PubMed

Soloshonok, Vadim A; Cai, Chaozhong; Yamada, Takeshi; Ueki, Hisanori; Ohfune, Yasufumi; Hruby, Victor J

2005-11-02

This paper describes a systematic study of addition reactions between the chiral Ni(II) complex of the Schiff base of glycine with (S)-o-[N-(N-benzylprolyl)amino]benzophenone and (S)- or (R)-3-[(E)-enoyl]-4-phenyl-1,3-oxazolidin-2-ones as a general and synthetically efficient approach to beta-substituted pyroglutamic acids and relevant compounds. These reactions were shown to occur at room temperature in the presence of nonchelating organic bases and, most notably, with very high (>98% diastereomeric excess (de)) stereoselectivity at both newly formed stereogenic centers. The stereochemical outcome of the reactions was found to be overwhelmingly controlled by the stereochemical preferences of the Michael acceptors, and the chirality of the glycine complex influenced only the reaction rate. Thus, in the reactions of both the (S)-configured Ni(II) complex and the Michael acceptors, the reaction rates were exceptionally high, allowing preparation of the corresponding products with virtually quantitative (>98%) chemical and stereochemical yields. In contrast, reactions of the (S)-configured Ni(II) complex and (R)-configured Michael acceptors proceeded at noticeably lower rates, but the addition products were obtained in high diastereo- and enantiomeric purity. To rationalize the remarkably high and robust stereoselectivity observed in these reactions, we consider an enzyme-substrate-like mode of interaction involving a topographical match or mismatch of two geometric figures. Excellent chemical and stereochemical yields, combined with the simplicity and operational convenience of the experimental procedures, render the present method of immediate use for preparing various beta-substituted pyroglutamic acids and related compounds.

Value-Added and Other Methods for Measuring School Performance: An Analysis of Performance Measurement Strategies in Teacher Incentive Fund Proposals. Research Brief

ERIC Educational Resources Information Center

National Center on Performance Incentives, 2008

2008-01-01

In "Value-Added and Other Methods for Measuring School Performance: An Analysis of Performance Measurement Strategies in Teacher Incentive Fund Proposals"--a paper presented at the February 2008 National Center on Performance Incentives research to policy conference--Robert Meyer and Michael Christian examine select performance-pay plans…

75 FR 57987 - SES Performance Review Board

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-23

... the Office of Personnel Management, one or more SES Performance Review Boards. The Board shall review.... Larry Baden--Deputy Chairman for Management and Budget. Michael Burke--Chief Information Officer. Sunil Iyengar--Director, Research & Analysis. William O'Brien--Senior Advisor for Program Innovation. Kathleen...

Dr Michaels® product family (also branded as Soratinex®) versus Methylprednisolone aceponate - a comparative study of the effectiveness for the treatment of plaque psoriasis.

PubMed

Hercogovấ, J; Fioranelli, M; Gianfaldoni, S; Chokoeva, A A; Tchernev, G; Wollina, U; Tirant, M; Novotny, F; Roccia, M G; Maximov, G K; França, K; Lotti, T

2016-01-01

As one of the most common dermatologic chronic-recurrent disease, variable therapeutic options are available today for management of psoriasis. Although topical high potency corticosteroids, alone or in association with salicylic acid or vitamin D analogues, are still considered the best treatment, they do not seem to possess the capability for a long-term control of the disease or prevent recurrences, as their side effects are major contraindications for continuative use. The aim of this study was to investigate whether Dr. Michaels® product family is comparable to methylprednisolone aceponate (MPA) as a viable alternative treatment option for the treatment and management of stable chronic plaque psoriasis. Thirty adults (13 male, 17 female, mean age 40 years) with mild to severe stable chronic plaque psoriasis, were included in the study. Patients were advised to treat the lesions of the two sides of their body (left and right) with two different unknown modalities for 8 weeks; the pack of Dr. Michaels® products on the left side (consisting of a cleansing gel, an ointment and a skin conditioner) and a placebo pack on the right side, consisting of a cleansing gel, methylprednisolone ointment and a placebo conditioner. Assessment was done using the Psoriasis Activity Severity Index (PASI) scores before treatment and after 2, 4, 6 and 8 weeks. The results achieved with the Dr. Michaels® (Soratinex®) product family for the treatment of chronic plaque psoriasis were better than the results achieved with methylprednisolone aceponate (MPA), even though quicker resolution was achieved with the steroid with 45% of patients achieving resolution within 8-10 days in comparison to 5-6 weeks in the Dr. Michaels® (Soratinex®) group. Before therapy, the mean PASI score of the LHS in Dr. Michaels® (Soratinex®) group was 13.8±4.1 SD and 14.2±4.2 SD in the RHS methylprednisolone aceponate (MPA) group. After 8 weeks of treatment 62% of the Dr. Michaels® (Soratinex®) group had achieved resolution whilst in the methylprednisolone aceponate (MPA) group, the figure remained at 45%. The mean PASI score after 8 weeks of treatment was calculated and in the LHS Dr. Michaels® (Soratinex®) group it was 2.8±1.6 SD and 6.8±2.4 SD in the RHS methylprednisolone aceponate group. In the RHS -methylprednisolone aceponate (MPA) group, 22% of patients failed to respond to the treatment in comparison to 6% in the LHS Dr. Michaels® (Soratinex®) group. Based on the results of this study, Dr. Michaels® products are a more effective treatment option, with insignificant side effects, compared to local treatment with methylprednisolone aceponate (MPA).

Lopez-Alegria performs EMCS-EC replace activity in Destiny laboratory module

NASA Image and Video Library

2006-12-29

ISS014-E-10647 (29 Dec. 2006) --- Astronaut Michael E. Lopez-Alegria, Expedition 14 commander and NASA space station science officer, performs the European Modular Cultivation System (EMSC) -- Experiment Container (EC) replacement in the Destiny laboratory of the International Space Station.

Lopez-Alegria performs EMCS-EC replace activity in Destiny laboratory module

NASA Image and Video Library

2006-12-29

ISS014-E-10639 (29 Dec. 2006) --- Astronaut Michael E. Lopez-Alegria, Expedition 14 commander and NASA space station science officer, performs the European Modular Cultivation System (EMSC) -- Experiment Container (EC) replacement in the Destiny laboratory of the International Space Station.

Foale performs IFM at the science window in the U.S. Lab during Expedition 8

NASA Image and Video Library

2004-04-23

ISS008-E-22271 (23 April 2004) --- Astronaut C. Michael Foale, Expedition 8 commander and NASA ISS science officer, performs in-flight maintenance (IFM) on the nadir window in the Destiny laboratory of the International Space Station (ISS).

Formulating a Strategic Response Plan for a High-Risk Seismic Event in New York City

DTIC Science & Technology

2013-03-01

65 Michael Daly, “Regulators Say Indian Point Nuclear Plant is Safe, but can Chernobyl -on-the- Hudson Happen?” Dailynews.com (March 15, 2011), http...www.nydailynews.com/new-york/regulators- indian-point-nuclear-plant-safe- chernobyl -on-the-hudson-happen-article-1.121117. 66 Ibid. 67 Ibid. 68...Michael Daly, “Regulators Say Indian Point Nuclear Plant is Safe, but can Chernobyl -on-the- Hudson Happen?” Dailynews.com (March 15, 2011), http

Tandem Aldol-Michael Reactions in Aqueous Diethylamine Medium: A Greener and Efficient Approach to Bis-Pyrimidine Derivatives

PubMed Central

Al-Majid, Abdullah M.; Barakat, Assem; AL-Najjar, Hany J.; Mabkhot, Yahia N.; Ghabbour, Hazem A.; Fun, Hoong-Kun

2013-01-01

A simple protocol, involving the green synthesis for the construction of novel bis-pyrimidine derivatives, 3a–i and 4a–e are accomplished by the aqueous diethylamine media promoted tandem Aldol-Michael reaction between two molecules of barbituric acid derivatives 1a,b with various aldehydes. This efficient synthetic protocol using an economic and environmentally friendly reaction media with versatility and shorter reaction time provides bis-pyrimidine derivatives with high yields (88%–99%). PMID:24317435

Team Performance Assessment and Measurement: Theory, Methods, and Applications. Series in Applied Psychology.

ERIC Educational Resources Information Center

Brannick, Michael T., Ed.; Salas, Eduardo, Ed.; Prince, Carolyn, Ed.

This volume presents thoughts on measuring team performance written by experts currently working with teams in fields such as training, evaluation, and process consultation. The chapters are: (1) "An Overview of Team Performance Measurement" (Michael T. Brannick and Carolyn Prince); (2) "A Conceptual Framework for Teamwork Measurement" (Terry L.…

76 FR 55904 - Michael J. Donahue; Notice of Termination of Exemption By Implied Surrender and Soliciting...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-09

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 6649-008] Michael J.... Date Initiated: September 1, 2011. d. Exemptee: Michael J. Donahue. e. Name and Location of Project.... Initiated Pursuant to: 18 CFR 4.106. g. Exemptee Contact Information: Mr. Michael J. Donahue, Route 3, Box...

76 FR 58264 - Michael J. Donahue; Notice of Termination of Exemption by Implied Surrender and Soliciting...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-20

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 6649-008] Michael J.... Date Initiated: September 13, 2011. d. Exemptee: Michael J. Donahue. e. Name and Location of Project.... Initiated Pursuant to: 18 CFR 4.106. g. Exemptee Contact Information: Mr. Michael J. Donahue, Route 3, Box...

75 FR 62635 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-12

... Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request... determine patients' satisfaction with services provided by or through the Michael E. DeBakey Home Care...: Patient Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form 10-0476. OMB Control Number...

77 FR 69550 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-19

... (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request AGENCY... information needed to determine patients' satisfaction with services provided by or through the Michael E...: Patient Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form 10-0476. OMB Control Number...

Maniac Talk - Michael Mishchenko

NASA Image and Video Library

2015-01-26

Michael Mishchenko Maniac Lecture, January 26, 2015 NASA climate scientist Dr. Michael I. Mishchenko presented a Maniac Talk entitled "How much first-principle physics do we need in remote-sensing and atmospheric-radiation research." Michael explained his skepticism and how it has shaped his contributions to the disciplines of electromagnetic scattering, radiative transfer, and remote sensing, which have found widespread use.

Expedition 9 Landing

NASA Image and Video Library

2004-10-24

Expedition 9 Flight Engineer Michael Fincke performs the traditional crew signing inside of his Russian search and rescue helicopter while Expedition 5 Flight Engineer Peggy Whitson looks on, Sunday, October 24, 2004. Photo Credit: (NASA/Bill Ingalls)

Hopins with ARED hardware

NASA Image and Video Library

2013-10-03

ISS037-E-006562 (3 Oct. 2013) --- NASA astronaut Michael Hopkins, Expedition 37 flight engineer, performs routine in-flight maintenance on the advanced Resistive Exercise Device (aRED) in the Tranquility node of the International Space Station.

Hopins with ARED hardware

NASA Image and Video Library

2013-10-03

ISS037-E-006563 (3 Oct. 2013) --- NASA astronaut Michael Hopkins, Expedition 37 flight engineer, performs routine in-flight maintenance on the advanced Resistive Exercise Device (aRED) in the Tranquility node of the International Space Station.

Barrett during TVIS maintenance

NASA Image and Video Library

2009-04-21

ISS019-E-008750 (21 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, performs in-flight maintenance on the Treadmill Vibration Isolation System (TVIS) in the Zvezda Service Module of the International Space Station.

Barrett during TVIS maintenance

NASA Image and Video Library

2009-04-21

ISS019-E-008752 (21 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, performs in-flight maintenance on the Treadmill Vibration Isolation System (TVIS) in the Zvezda Service Module of the International Space Station.

Barrett during TVIS maintenance

NASA Image and Video Library

2009-04-21

ISS019-E-008767 (21 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, performs in-flight maintenance on the Treadmill Vibration Isolation System (TVIS) in the Zvezda Service Module of the International Space Station.

Barrett during TVIS maintenance

NASA Image and Video Library

2009-04-21

ISS019-E-008764 (21 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, performs in-flight maintenance on the Treadmill Vibration Isolation System (TVIS) in the Zvezda Service Module of the International Space Station.

Outage management and health physics issue, 2007

DOE Office of Scientific and Technical Information (OSTI.GOV)

Agnihotri, Newal

2007-05-15

The focus of the May-June issue is on outage management and health physics. Major articles/reports in this issue include: India: a potential commercial opportunity, a U.S. Department of Commerce Report, by Joe Neuhoff and Justin Rathke; The changing climate for nuclear energy, by Skip Bowman, Nuclear Energy Insitute; Selecting protective clothing, by J. Mark Price, Southern California Edison; and Succssful refurbishment outage, by Sudesh K. Gambhir, Omaha Public Power District. Industry innovation articles in this issue are: Containment radiation monitoring spiking, by Michael W. Lantz and Robert Routolo, Arizona Public Service Company; Improved outage performance, by Michael Powell and Troymore » Wilfong, Arizona Public Service Company, Palo Verde Nuclear Generating Station; Stop repacking valves and achieve leak-free performance, by Kenneth Hart, PPL Susquehanna LLC; and Head assembly upgrade package, by Timothy Petit, Dominion Nuclear.« less

KENNEDY SPACE CENTER, FLA. -- A United Space Alliance (USA) technician (center) discusses aspects of Shuttle processing performed in the Solid Rocket Booster (SRB) Assembly and Refurbishment Facility (ARF) with NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik (right). NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.

NASA Image and Video Library

2003-12-19

KENNEDY SPACE CENTER, FLA. -- A United Space Alliance (USA) technician (center) discusses aspects of Shuttle processing performed in the Solid Rocket Booster (SRB) Assembly and Refurbishment Facility (ARF) with NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik (right). NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.

Documentation in a Software Maintenance Environment.

DTIC Science & Technology

1987-08-28

Michael Jackson Diagrams 0...8217 ." " . ." ." ""’, " , "" " - . -’" ,," ’" " " "’" d t Review of Documentation Techniques Michael Jackson Diagrams Michael Jackson diagrams show data...coupling and cohesion. Logic is not represented in this technique, which thus is of limited value. Advantages: Michael Jackson diagrams are similar

[An exceptional human relationship (Michael P. Kierkegaard, Søren Kierkegaard)].

PubMed

Jacobs, R

1978-01-01

There were a father and a son, Michael and Sören Kierkegaard, both highly talented, imaginitive, witty, humorous, especially interested in shrewd dialectrical dialogues respectively debates, both profound melancholy ponderers. But according to very own individuality their congeniality wasn't absolute. The father, being under a questionable rigorous opinion of sin, suffered from undeserved divine grace since early childhood. And Michael Kierkegaard made Sören anxious with the religious experience of original sin. This anxiety moved (touched or affected) the sensitive son mighty. Nevertheless he should not despair hopelessly like his unlucky father. On the contrary: Sørens incomparable melancholy, mental agony and anxiety (fear or anguish) forced the faith, existing independently of them, in a radical refining. That is why Sören Kierkegaard succeeded in sublimation of all psychological and philosophic (al) attitudes (or opinions) in the sphere of religiousness. And the result? A novel philosophy of life: Christian existentialism.

Barratt with TVIS in Service module

NASA Image and Video Library

2009-04-23

ISS019-E-009818 (23 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, performs in-flight maintenance on the Treadmill Vibration Isolation System (TVIS) in the Zvezda Service Module of the International Space Station.

Barratt with TVIS in Service module

NASA Image and Video Library

2009-04-23

ISS019-E-009857 (23 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, performs in-flight maintenance on the Treadmill Vibration Isolation System (TVIS) in the Zvezda Service Module of the International Space Station.

Barratt with TVIS in Service module

NASA Image and Video Library

2009-04-23

ISS019-E-009840 (23 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, performs in-flight maintenance on the Treadmill Vibration Isolation System (TVIS) in the Zvezda Service Module of the International Space Station.

Barratt with TVIS in Service module

NASA Image and Video Library

2009-04-23

ISS019-E-009856 (23 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, performs in-flight maintenance on the Treadmill Vibration Isolation System (TVIS) in the Zvezda Service Module of the International Space Station.

Barratt with TVIS in Service module

NASA Image and Video Library

2009-04-23

ISS019-E-009819 (23 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, performs in-flight maintenance on the Treadmill Vibration Isolation System (TVIS) in the Zvezda Service Module of the International Space Station.

Reactivity of Biliatresone, a Natural Biliary Toxin, with Glutathione, Histamine, and Amino Acids

PubMed Central

Koo, Kyung A.; Waisbourd-Zinman, Orith; Wells, Rebecca G.; Pack, Michael; Porter, John R.

2016-01-01

In our previous work, we identified a natural toxin, biliatresone, from Dysphania glomulifera and D. littoralis, endemic plants associated with outbreaks of biliary atresia in Australian neonatal livestock. Biliatresone is a very rare isoflavonoid with an α-methylene ketone between two phenyls, 1,2-diaryl-2-propenone, along with methylenedioxy, dimethoxyl, and hydroxyl functional groups, that causes extrahepatic biliary toxicity in zebrafish. The toxic core of biliatresone is a methylene in the α-position relative to the ketone of 1,2-diaryl-2-propenone that serves as an electrophilic Michael acceptor. The α-methylene of biliatresone spontaneously conjugated with water and methanol (MeOH), respectively, via Michael addition in a reverse phase high-performance liquid chromatography (RP-HPLC) analysis. We here report the reactivity of biliatresone toward glutathione (GSH), several amino acids, and other thiol- or imidazole-containing biomolecules. LC-MS and HPLC analysis of the conjugation reaction showed the reactivity of biliatresone to be in the order histidine > N-acetyl-d-cysteine (D-NAC) = N-acetyl-l-cysteine (L-NAC) > histamine > glutathione ≥ cysteine ≫ glycine > glutamate > phenylalanine, while serine and adenine had no reactivity due to intramolecular hydrogen bonding in the protic solvents. The reactivity of ethyl vinyl ketone (EVK, 1-penten-3-one), an example of a highly reactive α,ß-unsaturated ketone, toward GSH gave a 6.7-fold lower reaction rate constant than that of biliatresone. The reaction rate constant of synthetic 1,2-diaryl-2-propen-1-one (DP), a core structure of the toxic molecule, was 10-fold and 1.5-fold weaker in potency compared to the reaction rate constants of biliatresone and EVK, respectively. These results demostrated that the methylenedioxy, dimethoxyl, and hydroxyl functional groups of biliatresone contribute to the stronger reactivity of the Michael acceptor α-methylene ketone toward nucleophiles compared to that of DP and EVK. PMID:26713899

Reactivity of Biliatresone, a Natural Biliary Toxin, with Glutathione, Histamine, and Amino Acids.

PubMed

Koo, Kyung A; Waisbourd-Zinman, Orith; Wells, Rebecca G; Pack, Michael; Porter, John R

2016-02-15

In our previous work, we identified a natural toxin, biliatresone, from Dysphania glomulifera and D. littoralis, endemic plants associated with outbreaks of biliary atresia in Australian neonatal livestock. Biliatresone is a very rare isoflavonoid with an α-methylene ketone between two phenyls, 1,2-diaryl-2-propenone, along with methylenedioxy, dimethoxyl, and hydroxyl functional groups, that causes extrahepatic biliary toxicity in zebrafish. The toxic core of biliatresone is a methylene in the α-position relative to the ketone of 1,2-diaryl-2-propenone that serves as an electrophilic Michael acceptor. The α-methylene of biliatresone spontaneously conjugated with water and methanol (MeOH), respectively, via Michael addition in a reverse phase high-performance liquid chromatography (RP-HPLC) analysis. We here report the reactivity of biliatresone toward glutathione (GSH), several amino acids, and other thiol- or imidazole-containing biomolecules. LC-MS and HPLC analysis of the conjugation reaction showed the reactivity of biliatresone to be in the order histidine > N-acetyl-d-cysteine (D-NAC) = N-acetyl-l-cysteine (L-NAC) > histamine > glutathione ≥ cysteine ≫ glycine > glutamate > phenylalanine, while serine and adenine had no reactivity due to intramolecular hydrogen bonding in the protic solvents. The reactivity of ethyl vinyl ketone (EVK, 1-penten-3-one), an example of a highly reactive α,ß-unsaturated ketone, toward GSH gave a 6.7-fold lower reaction rate constant than that of biliatresone. The reaction rate constant of synthetic 1,2-diaryl-2-propen-1-one (DP), a core structure of the toxic molecule, was 10-fold and 1.5-fold weaker in potency compared to the reaction rate constants of biliatresone and EVK, respectively. These results demostrated that the methylenedioxy, dimethoxyl, and hydroxyl functional groups of biliatresone contribute to the stronger reactivity of the Michael acceptor α-methylene ketone toward nucleophiles compared to that of DP and EVK.

4. Photocopy of inkandwatercolor drawing (from St. Michael's Church) Rambusch, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Photocopy of ink-and-watercolor drawing (from St. Michael's Church) Rambusch, illustrator ca. 1932-37 INTERIOR, LOOKING NORTHEAST - St. Michael's Catholic Church, 519 East Third Street, Madison, Jefferson County, IN

Michael J. Fox: Spurring Research on Parkinson's

MedlinePlus

... on. Feature: Parkinson's Disease Michael J. Fox: Spurring Research on Parkinson's Past Issues / Winter 2014 Table of ... founded the Michael J. Fox Foundation for Parkinson's Research in the year 2000. Photo courtesy of Shutterstock " ...

Dignital Biological Converter

DTIC Science & Technology

2014-01-03

DARPA Contracting Officer: Michael Blackstone Submitted by: HEATHER GOUVIS Synthetic Genomics, Inc. 11149 NORTH TORREY PINES RD LA JOLLA, CA...Contracting Officer Representative (COR) Email: salit@nist.gov Michael Blackstone DARPA Contracting Officer Michael.Blackstone@darpa.mil DARPA

Catalytic asymmetric Michael reactions promoted by a lithium-free lanthanum-BINOL complex

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sasai, Hiroaki; Arai, Takayoshi; Shibasaki, Masakatsu

1994-02-23

In this communication, we report about a new lithium-free BINOL-lanthanum complex, which is quite effective in catalytic asymmetric Michael reaction. We have succeeded in developing effective asymmetric base catalysts, in particular, asymmetric ester enolate catalysts for asymmetric Michael reactions. Two asymmetric lanthanum complexes are now available, namely, BINOL-lanthanum-lithium complex, which is quite effective in catalytic asymmetric nitrosaldol reactions, and a new lithium-free BINOL-lanthanum ester enolate complex, that is very effective in catalytic asymmetric Michael reactions. The two complexes complement each other in their ability to catalyze asymmetric nitroaldol and asymmetric Michael reactions. 14 refs., 1 fig., 2 tabs.

Flexibly Global? Performing Culture and Identity in an Age of Uncertainty

ERIC Educational Resources Information Center

Giardina, Michael D.

2009-01-01

Presented as a symbolic interactive messy performance text, Michael Giardina sutures himself into and through the landscape of global social relations, including his own interpretive interactions of disconnection and reconnection with place, home, and nation. In so doing, and in these collages of lived textuality, he examines the complex,…

New eco-friendly animal bone meal catalysts for preparation of chalcones and aza-Michael adducts

PubMed Central

2012-01-01

Abstract Two efficient reactions were successfully carried out using Animal Bone Meal (ABM) and potassium fluoride or sodium nitrate doped ABMs as new heterogeneous catalysts under very mild conditions. After preparation and characterization of the catalysts, we first report their use in a simple and convenient synthesis of various chalcones by Claisen–Schmidt condensation and then in an aza-Michael addition involving several synthesized chalcones with aromatic amines. All the reactions were carried out at room temperature in methanol; the chalcone synthesis was also achieved in water environment under microwave irradiation. Doping ABM enhances the rate and yield at each reaction. Catalytic activities are discussed and the ability to re-use the ABM is demonstrated. Results For Claisen–Schmidt the use of ABM alone, yields never exceeded 17%. In each entry, KF/ABM and NaNO3/ABM (79-97%) gave higher yields than using ABM alone under thermic condition. Also the reaction proceeded under microwave irradiation in good yields (72-94% for KF/ABM and 81-97% for NaNO3/ABM) and high purity. For aza-Michael addition the use of ABM doped with KF or NaNO3 increased the catalytic activity remarkably. The very high yields could be noted (84-95% for KF/ABM and 81-94% for NaNO3/ABM). Conclusion The present method is an efficient and selective procedure for the synthesis of chalcones an aza-Michael adducts. The ABM and doped ABMs are a new, inexpensive and attractive solid supports which can contribute to the development of catalytic processes and reduced environmental problems. PMID:22721409

Chain Dynamic Formulations for Multibody System Tracked Vehicles (Preprint)

DTIC Science & Technology

2013-03-06

Michael Wallin 1 Ahmed K. Aboubakr 1 Paramsothy Jayakumar 2 Michael D. Letherwood 2 Ashraf Hamed 1 Ahmed A. Shabana 1...5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Michael Wallin; Ahmed Aboubakr; Paramsothy Jayakumar ; Michael Letherwood; Ashraf Hamed 5d...Taylor & Francis/CRC, Boca Raton, Florida. 16. Shabana, A. A., Hamed, A. M., Mohamed, A. A., Jayakumar , P., and Letherwood, M. D. 2012, “Use of B

MEANS 2: Microstructure- and Micromechanism-Sensitive Property Models for Advanced Turbine Disk and Blade Systems

DTIC Science & Technology

2009-12-31

f„„„,„ -L...-J..— - —I 1 / f+_—=p / —j \\-\\- 4A 14 4A»4 / 4A C4 M / »4.4C A4, «i »A OWOLC $-ISF s - csr !•» ’ML...Materials Society) Publications. 23. S . Ma, L. Carroll and T.M. Pollock, "Development of y Phase Stacking Faults during High Temperature Creep of Ru...into the design of advanced disk and blade systems 6. AUTHOR( S ) Michael J Mills 5. FUNDING NUMBERS FA9550-05-1-0135 7. PERFORMING ORGANIZATION

Michael E. Himmel | NREL

Science.gov Websites

E. Himmel Photo of Michael E. Himmel Michael Himmel Senior Research Fellow I-Molecular Biology ;Towards a molecular-level theory of carbohydrate processivity," Curr. Opinion Biotechnol. (2014 University, Department of Biochem. & Molecular Biol., Distinguished Alumnus (2014) Battelle Memorial

[The problem of evil in families--the filmmaker Michael Haneke].

PubMed

Skårderud, Finn

2010-09-23

With the beautiful and dark film "The white ribbon", from 2009, the Austrian film director Michael Haneke consolidated his status as an international success. A central theme in his films is evilness and its roots. But just as important is his ambition to develop films where evil is not only portrayed, but where spectators are challenged to relate to their own ethical standards and their role as spectators. Haneke is a highly original filmmaker with his consistent search for a film aesthetic that stimulates ethical self-reflection and mentalizing. He partly succeeds in this quest.

β-Amino acid catalyzed asymmetric Michael additions: design of organocatalysts with catalytic acid/base dyad inspired by serine proteases.

PubMed

Yang, Hui; Wong, Ming Wah

2011-09-16

A new type of chiral β-amino acid catalyst has been computationally designed, mimicking the enzyme catalysis of serine proteases. Our catalyst approach is based on the bioinspired catalytic acid/base dyad, namely, a carboxyl and imidazole pair. DFT calculations predict that this designed organocatalyst catalyzes Michael additions of aldehydes to nitroalkenes with excellent enantioselectivities and remarkably high anti diastereoselectivities. The unusual stacked geometry of the enamine intermediate, hydrogen bonding network, and the adoption of an exo transition state are the keys to understand the stereoselectivity. © 2011 American Chemical Society

An unusual Michael-induced skeletal rearrangement of a bicyclo[3.3.1]nonane framework of phloroglucinols to a novel bioactive bicyclo[3.3.0]octane.

PubMed

Vidali, Veroniki P; Mitsopoulou, Kornilia P; Dakanali, Marianna; Demadis, Konstantinos D; Odysseos, Andreani D; Christou, Yiota A; Couladouros, Elias A

2013-11-01

A novel skeletal rearrangement of bicyclo[3.3.1]nonane-2,4,9-trione (16) to an unprecedented highly functionalized bicyclo[3.3.0]octane system (17), induced by an intramolecular Michael addition, is presented. This novel framework was found to be similarly active to hyperforin (1), against PC-3 cell lines. A mechanistic study was examined in detail, proposing a number of cascade transformations. Also, reactivity of the Δ(7,10)-double bond was examined under several conditions to explain the above results.

78 FR 42748 - Virginia Resource Advisory Committee Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-17

... each meeting, contact: Michael Williams, Public Affairs Specialist, Supervisor's Office, 540-265-5173... building in order to view comments. FOR FURTHER INFORMATION CONTACT: Michael Williams, Public Affairs... for time for oral comments must be sent to Michael Williams, Public Affairs Specialist, George...

Synthesis of Triazole Derivatives of Levoglucosenone As Promising Anticancer Agents: Effective Exploration of the Chemical Space through retro-aza-Michael//aza-Michael Isomerizations.

PubMed

Tsai, Yi-Hsuan; Borini Etichetti, Carla M; Di Benedetto, Carolina; Girardini, Javier E; Martins, Felipe Terra; Spanevello, Rolando A; Suárez, Alejandra G; Sarotti, Ariel M

2018-04-06

The design and synthesis of biomass-derived triazoles and the in vitro evaluation as potential anticancer agents are described. The discovery of base-catalyzed retro-aza-Michael//aza-Michael isomerizations allowed the exploration of the chemical space by affording novel types of triazoles, difficult to obtain otherwise. Following this strategy, 2,4-disubstituted 1,2,3-triazoles could be efficiently obtained from the corresponding 1,4-disubstituted analogues.

I Am America Singing: Bob Dylan's Identity Unified through Linguistic Performance

ERIC Educational Resources Information Center

Callahan, Erin Colleen

2014-01-01

Focus on his biography and his performance in the media has long been the basis of interpretation of Bob Dylan's identity. This has resulted in the accepted critical theory of Dylan's identity as mercurial and lacking a central ipseity. However, as Michael Strachan argues, rock biography is an unstable genre because it treats its subjects as…

Producing the Docile Body: Analysing Local Area Under-Performance Inspection (LAUI)

ERIC Educational Resources Information Center

Clapham, Andrew

2015-01-01

Sir Michael Wilshaw, the head of the Office for Standards in Education (OfSTED), declared a "new wave" of Local Area Under-performance Inspections (LAUI) of schools "denying children the standard of education they deserve". This paper examines how the threat of LAUI played out over three mathematics lessons taught by a teacher…

Chemopreventive Agents from Physalis minima Function as Michael Reaction Acceptors

PubMed Central

Men, Ruizhi; Li, Ning; Ding, Chihong; Tang, Yingzhan; Xing, Yachao; Ding, Wanjing; Ma, Zhongjun

2016-01-01

Background: The fruits of some varieties of genus Physalis have been used as delicious fruits and functional food in the Northeast of China. Materials and Methods: To reveal the functional material basis, we performed bioactivity-guided phytochemical research and chemopreventive effect assay of the constituents from Physalis minima. Results: It was demonstrated that the ethyl acetate extract of P. minima L. (EEPM) had potential quinone reductase (QR) inducing activity with induction ratio (IR, QR induction activity) value of 1.47 ± 0.24, and glutathione binding property as potential Michael reaction acceptors (with an α, β-unsaturated ketone moiety). Furthermore, bioactivity-guided phytochemical research led eight compounds (1–8), which were elucidated as 3-isopropyl-5-acetoxycyclohexene-2-one-1 (1), isophysalin B (2), physalin G (3), physalin D (4), physalin I (5), physordinose B (6), stigmasterol-3-O-β-D-glucopyranoside (7) and 5α-6β-dihydroxyphysalin R (8) on the basis of nuclear magnetic resonance spectroscopy analyses and HRESIMS. Then, isophysalin B (2) and physordinose B (6) showed significant QR inducing activity with IR value of 2.80 ± 0.19 and 2.38 ± 0.46, respectively. SUMMARY An ultra-performance liquid chromatographic method with glutathione as the substrate was used to detect the Michael reaction acceptors in extracts of Physalis minima (EPM)We investigated the chemical constituents of EPM guided by biological activity methodIsophysalin B (1) and physordinose B (6) showed strong quinone reductase inducing activity with induction ratio values of 2.80 ± 0.19 and 2.38 ± 0.46This study generated useful information for consumers and many encourage researchers to utilize edible fruits from Physalis as a source of phytochemicals Abbreviations used: EPM: Extracts of Physalis minima, EEPM: Ethyl acetate extract of Physalis minima L., GSH: Glutathione, MRAs: Michael reaction acceptors, QR: Quinone reductase. PMID:27279713

Surface Modified Particles By Multi-Step Michael-Type Addition And Process For The Preparation Thereof

DOEpatents

Cook, Ronald Lee; Elliott, Brian John; Luebben, Silvia DeVito; Myers, Andrew William; Smith, Bryan Matthew

2005-05-03

A new class of surface modified particles and a multi-step Michael-type addition surface modification process for the preparation of the same is provided. The multi-step Michael-type addition surface modification process involves two or more reactions to compatibilize particles with various host systems and/or to provide the particles with particular chemical reactivities. The initial step comprises the attachment of a small organic compound to the surface of the inorganic particle. The subsequent steps attach additional compounds to the previously attached organic compounds through reactive organic linking groups. Specifically, these reactive groups are activated carbon—carbon pi bonds and carbon and non-carbon nucleophiles that react via Michael or Michael-type additions.

Establishment of Maximum Voluntary Compressive Neck Tolerance Levels

DTIC Science & Technology

2011-07-01

Bridges Casey Pirnstill Chris Burneka John Plaga Grant Roush Biosciences and Performance Division Vulnerability Analysis Branch July 2011...S) Michael Cote, John Buhrman, Nathaniel Bridges, Casey Pirnstill, Chris Burneka, John Plaga , Grant Roush 5d. PROJECT NUMBER OSMS 5e. TASK

78 FR 68019 - Performance Review Board Appointments

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-13

....; Chasteen, G. Taylor; Christian, Lisa A.; Clanton, Michael W.; Coffee, Richard; Cook, Cheryl L.; Davenport....; Paul, Matt; Pfaeffle, Frederick; Pino, Lisa; Repass, Todd; Robinson, Quinton; Romero, Ramona; Ruiz..., Lisa; Wright, Ann; Young, Benjamin; Young, Mike; Zehren, Christopher J. Marketing and Regulatory...

76 FR 10352 - Keyser, Michael J.; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-24

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ID-6495-000] Keyser, Michael J.; Notice of Filing Take notice that on February 15, 2011, Michael J. Keyser submitted for filing, an application for authority to hold interlocking positions, pursuant to section 305(b) of the...

Method for promoting Michael addition reactions

DOEpatents

Shah, Pankaj V.; Vietti, David E.; Whitman, David William

2010-09-21

Homogeneously dispersed solid reaction promoters having an average particle size from 0.01 .mu.m to 500 .mu.m are disclosed for preparing curable mixtures of at least one Michael donor and at least one Michael acceptor. The resulting curable mixtures are useful as coatings, adhesives, sealants and elastomers.

Substrate Control in Stereoselective Lanthionine Biosynthesis

PubMed Central

Tang, Weixin; Jiménez-Osés, Gonzalo; Houk, K. N.; van der Donk, Wilfred A.

2014-01-01

Enzymes are typically highly stereoselective catalysts that enforce a reactive conformation on their native substrates. We report here a rare example where the substrate controls the stereoselectivity of an enzyme-catalyzed Michael-type addition during the biosynthesis of lanthipeptides. These natural products contain thioether crosslinks formed by cysteine attack on dehydrated Ser and Thr residues. We demonstrate that several lanthionine synthetases catalyze highly selective anti additions in which the substrate (and not the enzyme) determines whether the addition occurs from the Re or Si face. A single point mutation in the peptide substrate completely inverted the stereochemical outcome of the enzymatic modification. Quantum mechanical calculations reproduced the experimentally observed selectivity and suggest that conformational restraints imposed by the amino acid sequence on the transition states determine the face selectivity of the Michael-type cyclization. PMID:25515891

Doing It All: Michael Sullivan--Weeks Public Library, NH

ERIC Educational Resources Information Center

Library Journal, 2005

2005-01-01

Michael Sullivan is a juggler--not a metaphorical one, a real one. He's also a library director, storyteller, competitive chess player, poet, speaker, and former children's librarian who continues to work with the kids in his community. This article summarizes the accomplishments and work of Michael Sullivan.

Michael J. Meaney: Award for Distinguished Scientific Contributions

ERIC Educational Resources Information Center

American Psychologist, 2012

2012-01-01

Presents Michael J. Meaney as one of the winners of the American Psychological Association's Award for Distinguished Scientific Contributions (2012). Michael J. Meaney has taken the phenomenon of "handling" of newborn rats and opened a new area of investigation that has given new meaning to epigenetics via his work demonstrating transgenerational…

Jack Michael's Motivation

ERIC Educational Resources Information Center

Miguel, Caio F.

2013-01-01

Among many of Jack Michael's contributions to the field of behavior analysis is his behavioral account of motivation. This paper focuses on the concept of "motivating operation" (MO) by outlining its development from Skinner's (1938) notion of "drive." Conceptually, Michael's term helped us change our focus on…

75 FR 22436 - Michael Williams-Control Exemption-St. Maries River Railroad, Inc.

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-28

... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35365] Michael Williams-Control Exemption-St. Maries River Railroad, Inc. Michael Williams (applicant),\\1\\ a noncarrier, has filed a verified notice of exemption to acquire control of St. Maries River Railroad, Inc. (STMA), a Class...

Language and Intercultural Education: An Interview with Michael Byram

ERIC Educational Resources Information Center

Porto, Melina

2013-01-01

This article reports an interview with Michael Byram, Professor Emeritus, University of Durham in the United Kingdom, during his visit to Argentina in September 2011. Michael Byram is one of the main international referents in intercultural education. The interview addresses issues such as language education, intercultural and citizenship…

Support for ICES International Symposium: Recruitment Dynamics of Exploited Marine Populations: Physical-biological Interactions

DTIC Science & Technology

1997-09-30

Environmental Science ,Chesapeake Biological Laboratory,PO Box 38,Solomons,MD,20688 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING...DYNAMICS OF EXPLOITED MARINE POPULATIONS: PHYSICAL-BIOLOGICAL INTERACTIONS Michael J. Fogarty University of Maryland Center for Environmental Science Chesapeake

STS-134 crew members Mike Fincke, Drew Feustel and Greg Chamitoff performing EVA Tile Repair Training.

NASA Image and Video Library

2010-01-28

JSC2010-E-014767 (28 Jan. 2010) --- NASA astronaut Michael Fincke, STS-134 mission specialist, participates in an EVA tile repair training session in the Space Vehicle Mock-up Facility at NASA's Johnson Space Center.

Evaluation of Impinging Stream Vortex Chamber Concepts for Liquid Rocket Engine Applications

NASA Technical Reports Server (NTRS)

Trinh, Huu P.; Bullard, Brad; Kopicz, Charles; Michaels, Scott; Turner, James (Technical Monitor)

2001-01-01

To pursue technology developments for future launch vehicles, NASA/Marshall Space Flight Center (MSFC) is examining vortex chamber concepts for liquid rocket engine applications. Past studies indicated that the vortex chamber schemes potentially have a number of advantages over conventional chamber methods. Due to the nature of the vortex flow, relatively cooler propellant streams tend to flow along the chamber wall. Hence, the thruster chamber can be operated without the need of any cooling techniques. This vortex flow also creates strong turbulence, which promotes the propellant mixing process. Consequently, the subject chamber concepts not only offer the system simplicity, but they also would enhance the combustion performance. The test results showed that the chamber performance was markedly high even at a low chamber length-to-diameter ratio (L/D). This incentive can be translated to a convenience in the thrust chamber packaging. Variations of the vortex chamber concepts have been introduced in the past few decades. These investigations include an ongoing work at Orbital Technologies Corporation (ORBITEC). By injecting the oxidizer tangentially at the chamber convergence and fuel axially at the chamber head end, Knuth et al. were able to keep the wall relatively cold. A recent investigation of the low L/D vortex chamber concept for gel propellants was conducted by Michaels. He used both triplet (two oxidizer and one fuel orifices) and unlike impinging schemes to inject propellants tangentially along the chamber wall. Michaels called the subject injection scheme as Impinging Stream Vortex Chamber (ISVC). His preliminary tests showed that high performance, with an Isp efficiency of 92%, can be obtained. MSFC and the U.S. Army are jointly investigating an application of the ISVC concept for the cryogenic oxygen/hydrocarbon propellant system. This vortex chamber concept is currently tested with gel propellants at AMCOM at Redstone Arsenal, Alabama. A version of this concept for the liquid oxygen (LOX)/hydrocarbon fuel (RPM) system has been derived from the one for the gel propellant.

Airpower in Counterinsurgency: The Search for Missing Doctrine

DTIC Science & Technology

2007-05-10

GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) LIEUTENANT COMMANDER THOMAS D. BARBER 5d. PROJECT NUMBER 5e. TASK...NUMBER Paper Advisor (if Any): LtCol MICHAEL P. HUGHES, USAF 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) 8...PERFORMING ORGANIZATION REPOR NUMBER Joint Military Operations Department Naval War College 686 Cushing Road

St. Michael's Improvement Program - A Collaborative Approach to Sustainable Cost Savings.

PubMed

Trafford, Anne; Jane, Danielle

2017-01-01

In response to a challenging financial environment and increasing patient demand, St. Michael's Hospital needed to find long-term sustainable solutions to continue to provide high-quality patient care and invest in key priorities. By conducting Operational Reviews in focused areas, the hospital achieved $7.4 million of in-year savings in the first year, found standardizations, process efficiencies and direct cost savings that positioned itself for success in future funding models. Initiatives were grounded in evidence and relied heavily on the effective execution by the leadership, front-line staff and physicians. As organizations face similar challenges, this journey can provide key learnings.

78 FR 2391 - CAlifornians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey v. Pacific Gas and...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-11

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. RP13-436-000] CAlifornians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey v. Pacific Gas and Electric Company... Energy Regulatory Commission (FERC); CAlifornians for Renewable Energy, Inc., Michael E. Boyd, and Robert...

Interview with Michael Apple: The Biography of a Public Intellectual

ERIC Educational Resources Information Center

Peters, Michael A.

2015-01-01

Michael W. Apple is the John Bascom Professor of Curriculum and Instruction and Educational Policy Studies in the Departments of Curriculum and Instruction (CI) and Educational Policy Studies (EPS) at the University of Wisconsin-Madison School of Education where he has taught since 1970. Michael Apple is one of the foremost educational theorists…

Markets, Marx, Modernity and Mathematics Education: A Response to Michael Apple.

ERIC Educational Resources Information Center

Gates, Peter

This paper is a response to Michael Apple's paper, "What Postmodernists Forget: Cultural Capital and Official Knowledge." The paper advocates Michael's identification of the current dangers and processes of the growth of new right ideologies in the development of subjectivity, society, and education. The differences in success in the education…

77 FR 61596 - Wheatley, Michael I.; Garrison, Drummond E.; Notice of Filing

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-10

...] Wheatley, Michael I.; Garrison, Drummond E.; Notice of Filing Take notice that on September 28, 2012, Michael I. Wheatley and Drummond E. Garrison submitted for filing, an application for authority to hold... the ``eFiling'' link at http://www.ferc.gov . Persons unable to file electronically should submit an...

76 FR 624 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-05

... Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request... Form 10-0476).'' SUPPLEMENTARY INFORMATION: Title: Patient Satisfaction Survey Michael E. DeBakey Home... satisfaction with the quality of services/care provided by home care program staff. An agency may not conduct...

W/V-Band Terrestrial Link Experiment (WTLE)

NASA Image and Video Library

2016-01-20

NASA Glenn researchers Jacki Houts, James Nessel and Michael Zemba perform a final inspection of the W/V-Band Terrestrial Link Experiment (WTLE) before it was transported to Albuquerque, New Mexico for testing. The experiment hardware includes a transmitter, which has been placed on the crest of the Sandia Mountains and a receiver (shown) placed at a research facility of the University of New Mexico. The wireless link spans 23km and will be used to study the effects of the atmosphere on high data-rate wireless communication links at 72 and 84 GHz. The goal of the experiment is to study these frequency bands for satellite communications.

75 FR 51168 - Members of Senior Executive Service Performance Review Boards

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-18

.... DeNard, Deputy Commissioner, Operations (LMSB) Alison L. Doone, Chief Financial Officer Vicki S. Duane...) Michael D. Julianelle, Director, Employee Plans (TEGE) Gregory E. Kane, Deputy Chief Financial Officer...) Moises C. Medina, Director, Government Entities (TEGE) Terence V. Milholland, Chief Technology Officer...

76 FR 67402 - Performance Review Board Appointments

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-01

....; Harden, Krysta; Hipp, Janie; Holtzman, Max T.; Jett, Carole E.; MacMillian, Anne; Mande, Jerold; Mills...; Christian, Lisa A.; Clanton, Michael W.; Davenport, Peter; Douglas, Walt; Foster, Andrea L.; Golden, John....; White, Sharmian L.; Wilburn, Curtis; Wilusz, Lisa; Worthington, Ruth M.; Young, Benjamin; Young, Mike...

Development of New Generation of Multibody System Computer Software

DTIC Science & Technology

2012-04-12

DEVELOPMENT OF NEW GENERATION OF MULTIBODY SYSTEM COMPUTER SOFTWARE Ahmed A. Shabana University of Illinois at Chicago Paramsothy Jayakumar ...Paramsothy Jayakumar ; Michael Letherwood 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES

KENNEDY SPACE CENTER, FLA. -- From left, a United Space Alliance (USA) technician discusses aspects of Shuttle processing performed in the Solid Rocket Booster (SRB) Assembly and Refurbishment Facility (ARF) with USA Vice President and Space Shuttle Program Manager Howard DeCastro and NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.

NASA Image and Video Library

2003-12-19

KENNEDY SPACE CENTER, FLA. -- From left, a United Space Alliance (USA) technician discusses aspects of Shuttle processing performed in the Solid Rocket Booster (SRB) Assembly and Refurbishment Facility (ARF) with USA Vice President and Space Shuttle Program Manager Howard DeCastro and NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.

NASA Catches Tropical Storm Leslie and Hurricane Michael in the Atlantic

NASA Image and Video Library

2017-12-08

This visible image of Tropical Storm Leslie and Hurricane Michael was taken by the MODIS instrument aboard both NASA's Aqua and Terra satellites on Sept. 9 at 12:50 p.m. EDT. Credit: NASA Goddard/MODIS Rapid Response Team -- Satellite images from two NASA satellites were combined to create a full picture of Tropical Storm Leslie and Hurricane Michael spinning in the Atlantic Ocean. Imagery from NASA's Aqua and Terra satellites showed Leslie now past Bermuda and Michael in the north central Atlantic, and Leslie is much larger than the smaller, more powerful Michael. Images of each storm were taken by the Moderate Resolution Imaging Spectroradiometer, or MODIS instrument that flies onboard both the Aqua and Terra satellites. Both satellites captured images of both storms on Sept. 7 and Sept. 10. The image from Sept. 7 showed a much more compact Michael with a visible eye. By Sept. 10, the eye was no longer visible in Michael and the storm appeared more elongated from south to north. To continue reading go to: 1.usa.gov/NkUPqn NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Polydopamine-mediated surface-functionalization of graphene oxide for heavy metal ions removal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dong, Zhihui; University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100049; Zhang, Feng

2015-04-15

By utilizing polydopamine (PD) nano-thick interlayer as mediator, polyethylenimine (PEI) brushes with abundant amine groups were grafted onto the surface of PD coated graphene oxide (GO) uniformly via a Michael-Addition reaction and produced a PEI–PD/GO composite nanosheets. The PEI–PD/GO composite exhibited an improved performance for adsorption of heavy metal ions as compared to PEI-coated GO and pure GO. The adsorption capacities for Cu{sup 2+}, Cd{sup 2+}, Pb{sup 2+}, Hg{sup 2+} are up to 87, 106, 197, and 110 mg/g, respectively. To further make the GO based composite operable, PEI–PD/RGO aerogel was prepared through hydrothermal and achieved a high surface areamore » up to 373 m{sup 2}/g. Although the adsorption capacity of PEI–PD/RGO aerogel for heavy metal ions decreases a little as compared to PEI–PD/GO composite dispersion (38, 32, 95, 113 mg/g corresponding to Cu{sup 2+}, Cd{sup 2+}, Pb{sup 2+}, and Hg{sup 2+}, respectively), it could be recycled several times in a simple way by releasing adsorbed metal ions, indicating its potential application for cleaning wastewater. - Graphical abstract: Polyethylenimine (PEI) brushes were grafted onto the surface of graphene oxide (GO) uniformly via a Michael-Addition reaction between the PEI and polydopamine interlayer coated on GO surface. The PEI–PD/GO composite exhibited an improved performance for adsorption of heavy metal ions compared to PEI-coated GO and pure GO. - Highlights: • We prepared polyethylenimine grafted polydopamine-mediated graphene oxide composites. • Introduction of PD layer increases metal ions adsorption capacity. • PEI–PD/RGO aerogel exhibited a superior adsorption performance. • PEI–PD/RGO aerogel can be recycled several times in a simple way.« less

Interview with J. Michael Thompson

ERIC Educational Resources Information Center

Randall, Mary Elisabeth

2004-01-01

J. Michael Thompson is the Vice Provost for Enrollment Management and Dean of Admission and Financial Aid at the University of Southern California. J. Michael has worked in higher education for more than 30 years in a variety of roles at small private and mid-sized and large public universities, and now at USC, a large private university. He has…

Veteran’s Health Care Issues

DTIC Science & Technology

2007-11-30

Affairs Dr. Michael J. Kussman , in U.S. Congress, House Committee on Veterans’ Affairs Subcommittee on Oversight and Investigations, hearing on...Health, Department of Veterans Affairs, Michael Kussman , in U.S. Congress, House Committee on Appropriations, Subcommittee on Military Construction...Department of Veterans Affairs Dr. Michael J. Kussman , in U.S. Congress, House Committee on Veterans’ Affairs Subcommittee on Oversight and

78 FR 6851 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-31

... (Patient Satisfaction Survey Michael E. DeBakey Home Care Program) Activity: Comment Request AGENCY... Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form 10-0476. OMB Control Number: 2900-0775. Type... gather feedback from patients regarding their satisfaction with the quality of services/care provided by...

Michael Young and the Curriculum Field in South Africa

ERIC Educational Resources Information Center

Hoadley, Ursula

2015-01-01

The paper addresses the question of what we should make of Michael Young's recent work with respect to curriculum theory by considering the particular case of South African curriculum reform. The paper thus traces two trajectories: the evolution of Michael Young's ideas over time and South African curriculum reform in the post-apartheid period.…

Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions.

PubMed

Jackson, Paul A; Widen, John C; Harki, Daniel A; Brummond, Kay M

2017-02-09

Although Michael acceptors display a potent and broad spectrum of bioactivity, they have largely been ignored in drug discovery because of their presumed indiscriminate reactivity. As such, a dearth of information exists relevant to the thiol reactivity of natural products and their analogues possessing this moiety. In the midst of recently approved acrylamide-containing drugs, it is clear that a good understanding of the hetero-Michael addition reaction and the relative reactivities of biological thiols with Michael acceptors under physiological conditions is needed for the design and use of these compounds as biological tools and potential therapeutics. This Perspective provides information that will contribute to this understanding, such as kinetics of thiol addition reactions, bioactivities, as well as steric and electronic factors that influence the electrophilicity and reversibility of Michael acceptors. This Perspective is focused on α,β-unsaturated carbonyls given their preponderance in bioactive natural products.

"Lyle, Lyle, Crocodile": A New Musical Based on the Books by Bernard Waber. Cue Sheet for Teachers.

ERIC Educational Resources Information Center

Selwyn, Karen P.

This performance guide is designed for teachers to use with students before and after a performance of "Lyle, Lyle, Crocodile," a musical based on the books by Bernard Waber, with book by Michael Slade, music by David Evans, and lyrics by Mindi Dickstein. The guide, called a "Cuesheet," contains four activity sheets for use in…

STS-43 crewmembers perform various tasks on OV-104's aft flight deck

NASA Image and Video Library

1991-08-11

STS043-37-012 (2-11 Aug 1991) --- Three STS-43 astronauts are busy at work onboard the earth-orbiting space shuttle Atlantis. Astronaut Shannon W. Lucid is pictured performing one of several tests on Computer hardware with space station applications in mind. Sharing the aft flight deck with Lucid are Michael A. Baker (left), pilot and John E. Blaha, mission commander.

MS Foale performs maintenance on middeck

NASA Image and Video Library

1999-12-21

S103-E-5184 (21 December 1999) --- Astronaut C. Michael Foale, mission specialist, performs a minor maintenance task on the mid deck of the Earth-orbiting Space Shuttle Discovery. The long rectangular structure near Foale's head is the escape pole, which has been standard equipment on the shuttle fleet since 1988. The photo was recorded with an electronic still camera (ESC) at 10:39:31 GMT, Dec. 21, 1999.

MELFI Urine Sample First Insertion

NASA Image and Video Library

2009-04-11

ISS019-E-005715 (11 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, performs an insertion of urine samples into the Minus Eighty Degree Laboratory Freezer for ISS (MELFI) as part of the Nutritional Status Assessment (NUTRITION) study in the Japanese Kibo laboratory of the International Space Station.

Management Development. [Concurrent Symposium Session at AHRD Annual Conference, 1998.

ERIC Educational Resources Information Center

1998

This document contains four papers from a symposium on management development. "The Effect of Supervisor/Subordinate Relationship on Subordinate Performance, Role Ambiguity and Conflict, and Job Satisfaction" (Michael J. Nocera, Judith A. Kolb) finds that a strong perceived relationship with supervisors was negatively correlated with…

78 FR 30861 - Membership of the Office of the Secretary Performance Review Board

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-23

... Officer and Assistant Secretary for Administration Frederick E. Stephens, Deputy Assistant Secretary for... T. Alston, Director, Financial Reporting and Internal Controls Michael E. Phelps, Director, Office of Budget Lisa Casias, Director for Financial Management and Deputy Chief Financial Officer Office of...

75 FR 15752 - Sunshine Act Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-30

...)--191, Assessment of Debris Accumulation on Pressurized Water Reactor (PWR) Sump Performance (Public... Fuel Cycle Oversight Process Revisions (Public Meeting). (Contact: Michael Raddatz, 301-492-3108.) This..., Employee/Labor Relations and Work Life Branch, at 301-492-2230, TDD: 301-415-2100, or by e-mail at angela...

75 FR 18907 - Sunshine Federal Register Notice

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-13

...)-191, Assessment of Debris Accumulation on Pressurized Water Reactor (PWR) Sump Performance (Public... Fuel Cycle Oversight Process Revisions (Public Meeting). (Contact: Michael Raddatz, 301-492-3108.) This... Bolduc, Chief, Employee/Labor Relations and Work Life Branch, at 301-492-2230, TDD: 301-415-2100, or by e...

Music Literacy in an Israeli Kindergarten

ERIC Educational Resources Information Center

Gluschankof, Claudia; Kenney, Susan Hobson

2011-01-01

This article reports on a learner-centered kindergarten music program at Gan Michael Kindergarten in Israel. Actual experiences with stories and pictures provide examples of young children engaged in music making as performers, composers, and analytical listeners. The stories include teacher thoughts and reflections, providing a model of teacher…

Understanding Summary Statistics and Graphical Techniques to Compare Michael Jordan versus LeBron James

ERIC Educational Resources Information Center

Williams, Immanuel James; Williams, Kelley Kim

2016-01-01

Understanding summary statistics and graphical techniques are building blocks to comprehending concepts beyond basic statistics. It's known that motivated students perform better in school. Using examples that students find engaging allows them to understand the concepts at a deeper level.

77 FR 30047 - Notice of Opportunity for Public Comment on Surplus Property Release at Michael J Smith Field...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-21

... Comment on Surplus Property Release at Michael J Smith Field, Beaufort, NC AGENCY: Federal Aviation... J Smith Field, be used for aeronautical purposes. DATES: Comments must be received on or before June... property at the Michael J Smith Field. The property consists of one parcel located on the north side of...

Enantioselective total synthesis of (-)-strychnine using the catalytic asymmetric Michael reaction and tandem cyclization.

PubMed

Ohshima, Takashi; Xu, Youjun; Takita, Ryo; Shimizu, Satoshi; Zhong, Dafang; Shibasaki, Masakatsu

2002-12-11

The enantioselective total synthesis of (-)-strychnine was accomplished through the use of the highly practical catalytic asymmetric Michael reaction (0.1 mol % of (R)-ALB, more than kilogram scale, without chromatography, 91% yield and >99% ee) as well as a tandem cyclization that simultaneously constructed B- and D-rings (>77% yield). Moreover, newly developed reaction conditions for thionium ion cyclization, NaBH3CN reduction of the imine moiety in the presence of Lewis acid to prevent ring opening reaction, and chemoselective reduction of the thioether (desulfurization) in the presence of exocyclic olefin were pivotal to complete the synthesis. The described chemistry paves the way for the synthesis of more advanced Strychnos alkaloids.

A Promiscuous De Novo Retro-Aldolase Catalyzes Asymmetric Michael Additions via Schiff Base Intermediates.

PubMed

Garrabou, Xavier; Beck, Tobias; Hilvert, Donald

2015-05-04

Recent advances in computational design have enabled the development of primitive enzymes for a range of mechanistically distinct reactions. Here we show that the rudimentary active sites of these catalysts can give rise to useful chemical promiscuity. Specifically, RA95.5-8, designed and evolved as a retro-aldolase, also promotes asymmetric Michael additions of carbanions to unsaturated ketones with high rates and selectivities. The reactions proceed by amine catalysis, as indicated by mutagenesis and X-ray data. The inherent flexibility and tunability of this catalyst should make it a versatile platform for further optimization and/or mechanistic diversification by directed evolution. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

ANALYZING THE SUSTAINABILITY OF GREEN PROCESSES: METHODS FOR EVALUATING THE FOUR E'S

EPA Science Inventory

Analyzing the Sustainability of Green Processes: Methods for Evaluating the Four E's

By Raymond L. Smith and Michael A. Gonzalez

A considerable amount of research is being performed under the banners of "sustainable" and/or "green." The development of chemistries...

75 FR 57974 - Senior Executive Service Performance Review Board

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-23

... individuals listed below: Aguilar, David V. Alexander, Barbara Alikhan, Arif Anderson, Audrey Anderson, Gary L. Armstrong, Charles R. Ayala, Janice Aytes, Michael L. Bacon, Roxana Baldwin, William D. Baroukh, Nader Barr... N. Muenchau, Ernest Myers, David L. Neal, Jeffrey R. Neufeld, Donald W. Nicholson, David O'Connell...

78 FR 70027 - Senior Executive Service; Performance Review Board

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-22

.... SYKES, MERLE L. SYNAKOWSKI, EDMUND J. TALBOT JR, GERALD L. TAYLOR, CHARLES W. THOMPSON, MICHAEL A..., WILLIAM N. BURROWS, CHARLES W. BUTTRESS, LARRY D. CADIEUX, GENA E. CALBOS, PHILIP T. CALLAHAN, SAMUEL N..., JAMES MELBOURN DURANT, CHARLES K. ECKROADE, WILLIAM A. EDWARDS III, ROBERT E. EHLI, CATHY L. ELKIND...

Nutrition and Repository: Insertion of Urine Sample into MELFI

NASA Image and Video Library

2009-04-18

ISS019-E-010170 (18 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, performs an insertion of urine samples into the Minus Eighty Degree Laboratory Freezer for ISS (MELFI) as part of the Nutritional Status Assessment (NUTRITION) study in the Japanese Kibo laboratory of the International Space Station.

Nutrition and Repository: Insertion of Urine Sample into MELFI

NASA Image and Video Library

2009-04-18

ISS019-E-010165 (18 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, performs an insertion of urine samples into the Minus Eighty Degree Laboratory Freezer for ISS (MELFI) as part of the Nutritional Status Assessment (NUTRITION) study in the Japanese Kibo laboratory of the International Space Station.

Kelsey A. W. Horowitz | NREL

Science.gov Websites

Technologies, processes, business approaches, and policies to drive clean energy technology cost reductions and Muhammad Alam. 2017. An analysis of the Cost and Performance of Photovoltaic Systems as a Function Wiley & Sons, Ltd. doi:10.1002/pip.2755 Horowitz, Kelsey A.W. and Michael Woodhouse. "Cost and

Teach the History and Practice of Science

ERIC Educational Resources Information Center

Spillane, Nancy K.

2013-01-01

Through the reading, study, and performance of "Copenhagen", a play by Michael Frayn, chemistry students see the application of nuclear chemistry content, acquire a better understanding of the continuum from scientific research to technology design, and also become aware of the many and varied interrelationships of science with history…

Plan Aggregation for Strong Cyclic Planning in Nondeterministic Domains

DTIC Science & Technology

2014-07-23

ACRONYM(S) ARO 8. PERFORMING ORGANIZATION REPORT NUMBER 19a. NAME OF RESPONSIBLE PERSON 19b. TELEPHONE NUMBER Michael Cox Ron Alford, Ugur Kuter...ScienceDirect Artificial Intelligence www.elsevier.com/locate/artint Plan aggregation for strong cyclic planning in nondeterministic domains Ron Alford a,∗, Ugur

Condition and Performance Rating Procedures for Rubble Breakwaters and Jetties

DTIC Science & Technology

1998-11-01

coastal community whose excellent ideas helped guide this work. Dr. Michael J. O’Connor is Director of USACERL. Chapter 1 Introduction 1 Introduction...headquarters. Concepts for the condition rating procedures were generated by the authors, the CSAG, and other members of the Corps’ coastal community . These

STS-134 crew members Mike Fincke, Drew Feustel and Greg Chamitoff performing EVA Tile Repair Training.

NASA Image and Video Library

2010-01-28

JSC2010-E-014761 (28 Jan. 2010) --- NASA astronauts Greg Chamitoff (left), Andrew Feustel and Michael Fincke, all STS-134 mission specialists, participate in an EVA tile repair training session in the Space Vehicle Mock-up Facility at NASA's Johnson Space Center.

STS-134 crew members Mike Fincke, Drew Feustel and Greg Chamitoff performing EVA Tile Repair Training.

NASA Image and Video Library

2010-01-28

JSC2010-E-014766 (28 Jan. 2010) --- NASA astronaut Michael Fincke (left), STS-134 mission specialist, participates in an EVA tile repair training session in the Space Vehicle Mock-up Facility at NASA's Johnson Space Center. Instructor John Ray assisted Fincke.

STS-134 crew members Mike Fincke, Drew Feustel and Greg Chamitoff performing EVA Tile Repair Training.

NASA Image and Video Library

2010-01-28

JSC2010-E-014762 (28 Jan. 2010) --- NASA astronauts Greg Chamitoff (left), Andrew Feustel and Michael Fincke, all STS-134 mission specialists, participate in an EVA tile repair training session in the Space Vehicle Mock-up Facility at NASA's Johnson Space Center.

DefenseLink Feature: Chairman Visits Japan and Republic of Korea, Nov. 5-8,

Science.gov Websites

Staff Navy Adm. Michael G. Mullen answers questions at a press availability with local media following Staff Navy Adm. Michael G. Mullen visits greets marines and staff assigned to the U.S. Embassy, Tokyo the Joint Chiefs of Staff U.S. Navy Adm. Michael G. Mullen, right, and Japanese Chief of Defense Adm

Development of a Fragment-Based in Silico Profiler for Michael Addition Thiol Reactivity.

PubMed

Ebbrell, David J; Madden, Judith C; Cronin, Mark T D; Schultz, Terry W; Enoch, Steven J

2016-06-20

The Adverse Outcome Pathway (AOP) paradigm details the existing knowledge that links the initial interaction between a chemical and a biological system, termed the molecular initiating event (MIE), through a series of intermediate events, to an adverse effect. An important example of a well-defined MIE is the formation of a covalent bond between a biological nucleophile and an electrophilic compound. This particular MIE has been associated with various toxicological end points such as acute aquatic toxicity, skin sensitization, and respiratory sensitization. This study has investigated the calculated parameters that are required to predict the rate of chemical bond formation (reactivity) of a dataset of Michael acceptors. Reactivity of these compounds toward glutathione was predicted using a combination of a calculated activation energy value (Eact, calculated using density functional theory (DFT) calculation at the B3YLP/6-31G+(d) level of theory, and solvent-accessible surface area values (SAS) at the α carbon. To further develop the method, a fragment-based algorithm was developed enabling the reactivity to be predicted for Michael acceptors without the need to perform the time-consuming DFT calculations. Results showed the developed fragment method was successful in predicting the reactivity of the Michael acceptors excluding two sets of chemicals: volatile esters with an extended substituent at the β-carbon and chemicals containing a conjugated benzene ring as part of the polarizing group. Additionally the study also demonstrated the ease with which the approach can be extended to other chemical classes by the calculation of additional fragments and their associated Eact and SAS values. The resulting method is likely to be of use in regulatory toxicology tools where an understanding of covalent bond formation as a potential MIE is important within the AOP paradigm.

#BlackLivesMatter: A Call for Transformative Leadership

ERIC Educational Resources Information Center

Watson, Terri N.; Rivera-McCutchen, Rosa L.

2016-01-01

Michael Pelligrino is a novice principal in a large urban high school. After a rocky yet somewhat successful first year as the principal of Hilltop High School, tensions in the school and surrounding community are at an all-time high. The deaths of unarmed Black men, women, and children by law enforcement agents nationwide have led hundreds of…

Eco-friendly polyethylene glycol promoted Michael addition reactions of α,β-unsaturated carbonyl compounds

EPA Science Inventory

Abstract- Intra- and inter-nucleophilic addition reactions of different unsaturated compounds were found to be highly effective without any additives in PEG-400 as a recyclable reaction medium under neutral conditions.

Covalent Modifiers: A Chemical Perspective on the Reactivity of α,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions

PubMed Central

Jackson, Paul A.; Widen, John C.; Harki, Daniel A.; Brummond, Kay M.

2017-01-01

Although Michael acceptors display a potent and broad spectrum of bioactivity, they have largely been ignored in drug discovery because of their presumed indiscriminate reactivity. As such, a dearth of information exists relevant to the thiol reactivity of natural products and their analogs possessing this moiety. In the midst of recently approved acrylamide-containing drugs, it is clear that a good understanding of the hetero-Michael addition reaction and the relative reactivities of biological thiols with Michael acceptors under physiological conditions is needed for the design and use of these compounds as biological tools and potential therapeutics. This perspective provides information that will contribute to this understanding, such as kinetics of thiol addition reactions, bioactivities, as well as steric and electronic factors that influence the electrophilicity and reversibility of Michael acceptors. This perspective is focused on α,β-unsaturated carbonyls given their preponderance in bioactive natural products. PMID:27996267

Strategic Studies Quarterly. Volume 8, Number 3, Fall 2014

DTIC Science & Technology

2014-01-01

Michael Guillot Measuring Military Power James Jay Carafano Strategy and Force Planning in a Time of Austerity BG Michael J . Meese, USA, Retired...Hudson, PhD Nori Katagiri, PhD Paul J . Springer, PhD Zachary J . Zwald, PhD Strategic Studies Quarterly (SSQ) (ISSN 1936-1815) is published quarterly...19 BG Michael J . Meese, USA, Retired Pensive Sword: Educating Officers in Austere Times ...................... 30 Stephen D. Chiabotti Feature

DefenseLink.mil - Pentagon Memorial Dedication

Science.gov Websites

Dept. photo by Army Staff Sgt. Michael J. Carden An entry stone at the Pentagon Memorial lists the their lives during the Sept. 11 terrorist attack on the Pentagon. Photo by Staff Sgt. Michael J. Carden Staff Sgt. Michael J. Carden A member of The United States Air Force Band practices before the start of

Hearts-and-Minds: A Strategy of Conciliation, Coercion, or Commitment?

DTIC Science & Technology

2012-09-01

benefits to modern conflicts remains problematic. According to Colonel (retired) Michael Crawshaw writing on evolution of British COIN for the United...Richmond, UK: Curzon Press, 2002), 11. 9. Michael Crawshaw , “The Evolution of British COIN,” Se- curity and Stabilisation: The Military Contribution...Afghanistan” (Cahier de la Recherche, France: November 2011), 42. 12. Ibid., 43. 13. Michael Crawshaw , “The Evolution of British COIN,” Se- curity and

Development and Implementation of an Interactive Uniform Regulations Manual for the United States Marine Corps

DTIC Science & Technology

2006-09-01

IMPLEMENTATION OF AN INTERACTIVE UNIFORM REGULATIONS MANUAL FOR THE UNITED STATES MARINE CORPS by Michael H. Villar Carsten Krause...SUBTITLE: Development and Implementation of an Interactive Uniform Regulations Manual for the United States Marine Corps 6. AUTHOR(S) Michael H. Villar...IMPLEMENTATION OF AN INTERACTIVE UNIFORM REGULATIONS MANUAL FOR THE UNITED STATES MARINE CORPS Michael H. Villar Major, United States Marine Corps B.A

Understanding a Complex World: Why an Emphasis on Empathy Could Better Enable Army Leaders to Win

DTIC Science & Technology

2016-06-10

complexity and speed of human interactions. Through the analysis of case studies involving General Stanley McChrystal and Colonel Michael Steele , this...Future; Win; Dilemma; Leadership; McChrystal, Stanley; Steele , Michael 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF...Stanley McChrystal and Colonel Michael Steele , this thesis describes how each individual’s empathetic mindset resulted in both favorable and

Combat Service Support MOD II Design (CSS MOD II). Volume 2. Appendixes

DTIC Science & Technology

1986-10-01

through contractual aoreement with Michael Jackson , Ltd. London. The spelling, syntax, and word usage adopted throughout the document have been made...to conform to army standards. The design teas members wish to thank the followin, individuals for their assistances Mr. John Cameron, Michael Jackson , Ltd...JSP) methodology is a product of Michael Jackson Systems, Ltd., London, England. In 1984, Dr. Wilbur Payne, Director, TRADOC Operations Research

Envisioning a Career in Science, Technology, Engineering and Mathematics: Some Challenges and Possibilities

ERIC Educational Resources Information Center

Sharkawy, Azza

2015-01-01

In "How High School Students Envision Their STEM Career Pathways", Lin Zhang and Michael Barnett attempt to shed light on the problem of underrepresented students (e.g., Aboriginals, Hispanics, African Americans, urban, females) in STEM higher education and related careers by exploring, in general terms, five high school students' career…

PLASMA PROTEIN PROFILING AS A HIGH THROUGHPUT TOOL FOR CHEMICAL SCREENING USING A SMALL FISH MODEL

EPA Science Inventory

Hudson, R. Tod, Michael J. Hemmer, Kimberly A. Salinas, Sherry S. Wilkinson, James Watts, James T. Winstead, Peggy S. Harris, Amy Kirkpatrick and Calvin C. Walker. In press. Plasma Protein Profiling as a High Throughput Tool for Chemical Screening Using a Small Fish Model (Abstra...

75 FR 69061 - Senior Executive Service; Performance Review Board

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-10

..., Linda C Burrows, Charles W Buttress, Larry D Buzzard, Christine M Cadieux, Gena E Callahan, Samuel N... Bekkedahl, Larry N Bell, Melody C Berkowitz, Barry E Bieniawski, Andrew J Bishop, Clarence T Bishop, Tracey..., Douglas E Kane, Michael C Kaplan, Stan M Kearney, James H Kelly, Henry C Kelly, Larry C Kenchington, Henry...

75 FR 74748 - Senior Executive Service; Appointment of Members to the Performance Review Board

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-01

... Compensation--appointment expires on 09/30/11 SOL Katherine E. Bissell, Associate Solicitor for Civil Rights and Labor Management--appointment expires on 09/30/11 SOL Michael D. Felsen, Regional Solicitor, Boston--appointment expires on 09/30/12 SOL Deborah Greenfield, Deputy Solicitor--appointment expires on...

BISE (Bodies in the Space Environment) experiment

NASA Image and Video Library

2009-04-09

ISS019-E-005710 (9 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, uses Neurospat hardware to perform the Bodies in the Space Environment (BISE) experiment in the Destiny laboratory of the International Space Station. The Canadian Space Agency-sponsored BISE experiment studies how astronauts perceive up and down in microgravity.

BISE (Bodies in the Space Environment) experiment

NASA Image and Video Library

2009-04-18

ISS019-E-010155 (18 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, uses Neurospat hardware to perform the Bodies in the Space Environment (BISE) experiment in the Destiny laboratory of the International Space Station. The Canadian Space Agency-sponsored BISE experiment studies how astronauts perceive up and down in microgravity.

BISE (Bodies in the Space Environment) experiment

NASA Image and Video Library

2009-05-02

ISS019-E-013388 (2 May 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, uses Neurospat hardware to perform the Bodies in the Space Environment (BISE) experiment in the Destiny laboratory of the International Space Station. The Canadian Space Agency-sponsored BISE experiment studies how astronauts perceive up and down in microgravity.

BISE (Bodies in the Space Environment) experiment

NASA Image and Video Library

2009-04-09

ISS019-E-005706 (9 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, uses Neurospat hardware to perform the Bodies in the Space Environment (BISE) experiment in the Destiny laboratory of the International Space Station. The Canadian Space Agency-sponsored BISE experiment studies how astronauts perceive up and down in microgravity.

BISE (Bodies in the Space Environment) experiment

NASA Image and Video Library

2009-05-02

ISS019-E-013399 (2 May 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, uses Neurospat hardware to perform the Bodies in the Space Environment (BISE) experiment in the Destiny laboratory of the International Space Station. The Canadian Space Agency-sponsored BISE experiment studies how astronauts perceive up and down in microgravity.

75 FR 56504 - Membership of the Office of the Secretary Performance Review Board

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-16

..., Director, Office of Executive Resources, Office of Human Resources Management, Office of the Director, 14th... Institute of Standards and Technology Michael V. Culpepper, Chief Human Capitol Officer for NIST. National.... Yaag, Director, Office of Executive Resources. [FR Doc. 2010-22873 Filed 9-15-10; 8:45 am] BILLING CODE...

EVA 4 - Massimino during EVA

NASA Image and Video Library

2002-03-07

STS109-323-013 (7 March 2002) --- Astronaut Michael J. Massimino moves about in the cargo bay of the Space Shuttle Columbia while performing work on the Hubble Space Telescope (HST), partially visible behind him. Astronauts Massimino and James H. Newman (out of frame), mission specialists, were participating in the fourth STS-109 space walk (EVA-4).

Higher Education: Handbook of Theory and Research. Volume VI.

ERIC Educational Resources Information Center

Smart, John C., Ed.

Eleven papers on theory and research in higher education have the following titles and authors: "A Paradigm for Research on Higher Education" (William F. Massy); "Minority Student Access to, and Persistence and Performance in College: A Review of the Trends and Research Literature" (Shirley L. Mow and Michael T. Nettles);…

Unconventional Counterinsurgency: Leveraging Traditional Social Networks and Irregular Forces in Remote and Ungoverned Areas

DTIC Science & Technology

2010-05-13

Identity: Why We Are Losing Our Wars”, Michael Vlahos argues that today’s wars with non-state enemies are “above all, wars of identity.”29 Moreover, he...together these manuals powerfully reinforce Michael Vlahos ’ imperative to reshape the population and enemy narrative by co-opting identity.34...29 Michael Vlahos , "Fighting Identity: Why We Are Losing Our Wars," Military Review (United States

Topological Privacy: Lattice Structures and Information Bubbles for Inference and Obfuscation

DTIC Science & Technology

2016-12-19

AFRL-AFOSR-VA-TR-2017-0036 Topological Privacy Michael Erdmann CARNEGIE MELLON UNIVERSITY 5000 FORBES AVENUE PITTSBURGH, PA 15213-3815 02/22/2017...PERSON 19b. TELEPHONE NUMBER (Include area code) 19-12-2016 Final 15-10-2013 - 14-10-2016 Topological Privacy Erdmann, Michael, A. Carnegie Mellon...Michael Erdmann Carnegie Mellon University me@cs.cmu.edu December 19, 2016 Abstract Information has intrinsic geometric and topological structure, arising

Description and Evaluation of GDEM-V 3.0

DTIC Science & Technology

2009-02-06

Description and Evaluation of GDEM -V 3.0 Michael R. caRnes Ocean Sciences Branch Oceanography Division February 6, 2009 i REPORT DOCUMENTATION PAGE Form...include area code) b. ABSTRACT c. THIS PAGE 18. NUMBER OF PAGES 17. LIMITATION OF ABSTRACT Description and Evaluation of GDEM -V 3.0 Michael R. Carnes...unlimited. Unclassified Unclassified Unclassified UL 24 Michael R. Carnes (228) 688-5648 The GDEM (Generalized Digital Environment Model) has served as

Novel Array-Based Target Identification for Synergistic Sensitization of Breast Cancer to Herceptin

DTIC Science & Technology

2010-05-01

Tatsuya Azum, Eileen Adamson, Ryan Alipio, Becky Pio, Frank Jones, Dan Mercola. Chip- on- chip analysis of mechanism of action of HER2 inhibition in...Munawar, Kutbuddin S. Doctor, Michael Birrer, Michael McClelland, Eileen Adamson, Dan Mercola. Egr1 regulates the coordinated expression of numerous...Kemal Korkmaz, Mashide Ohmichi, Eileen Adamson, Michael McClelland, Dan Mercola. Identification of genes bound and regulated by ATF2/c-Jun

Structuring Z Specifications with Views

DTIC Science & Technology

1994-03-01

Gregory Abowd, Michael Jackson , Jeannette Wing, Michal Young and Pamela Zave, who gave me helpful comments on drafts of this pa- per. I am also grateful to...1988. Uac94] Michael Jackson , "Software Development Method", in A Classical Mind: Essays in Honour of C.A.R Hoare, ed. A.W Roscoe, Prentice Hall...International, 1994. ,0 26 [Jon86] Cliff B. Jones, Systematic Software Development Using VDM, Prentice Hall International, 1986. [JZ93] Michael Jackson and

Test and Evaluation of the Navy Occupational Health Information Management System (NOHIMS).

DTIC Science & Technology

1986-07-01

Naval Shipyard for NOHIMS with the assistance of Todd Merrill from the University of Washington and Michael Jackson , another industrial hygienist...initialize NOHIMS and learn how to use the system. As the industrial component of NOHIMS became operational in Bremerton, Michael Jackson assumed the role...interacting with the system. Since NO|IIMS was introduced at Bremerton, Michael Jackson has been involved in all aspects of system start-up and maintenance

An Analysis of New Small High Schools' On-Time Graduation Rates in New York City

ERIC Educational Resources Information Center

Dudley, Nathan

2017-01-01

Beginning in 2002, with the election of Mayor Michael Bloomberg, New York City's Department of Education undertook an unprecedented overhaul of the largest school district in the United States. Over the next 10 years the Department of Education closed more than 25 large, underperforming high schools, and created almost 200 new, small high schools,…

Meeting review: Bioinformatics and Medicine - from molecules to humans, virtual and real.

PubMed

Russell, Roslin

2002-01-01

The Industrialization Workshop Series aims to promote and discuss integration, automation, simulation, quality, availability and standards in the high-throughput life sciences. The main issues addressed being the transformation of bioinformatics and bioinformaticsbased drug design into a robust discipline in industry, the government, research institutes and academia. The latest workshop emphasized the influence of the post-genomic era on medicine and healthcare with reference to advanced biological systems modeling and simulation, protein structure research, protein-protein interactions, metabolism and physiology. Speakers included Michael Ashburner, Kenneth Buetow, Francois Cambien, Cyrus Chothia, Jean Garnier, Francois Iris, Matthias Mann, Maya Natarajan, Peter Murray-Rust, Richard Mushlin, Barry Robson, David Rubin, Kosta Steliou, John Todd, Janet Thornton, Pim van der Eijk, Michael Vieth and Richard Ward.

Michael Hauskeller: Sex and the Posthuman Condition : Palgrave-Macmillan, 2014, 98 pp.

PubMed

Miller, Lantz Fleming

2016-10-01

This new book from Michael Hauskeller explores the currently marketed or projected sex/love products that exhibit some trait of so-called "posthumanistic" theory or design. These products are so designated because of their intention to fuse high technologies, including robotics and computing, with the human user. The author offers several arguments for why the theory behind these products leads to inconsistencies. The book uses a unique approach to philosophical argument by enmeshing the argument's major points in a concomitant discussion of pieces from world literature pertaining to posthumanism. The method is compelling, heightened by great world authorial insights that rarely find their way into philosophy and shores up some strong argumentative points. Yet some of the argument still needs more elucidating.

Effect of the Civil-Military Relationship on the Philippine-American War

DTIC Science & Technology

2016-08-04

NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER U.S . Army Command and General Staff College ...Military Studies United States Army Command and General Staff College Fort Leavenworth, Kansas 2016 REPORT DOCUMENTATION PAGE Form Approved OMB No...Philippine-American War Sb. GRANT NUMBER Sc. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) Sd. PROJECT NUMBER MAJ Michael B. Long Se. TASK NUMBER Sf. WORK UNIT

Searching for a Different Understanding of Operational Art

DTIC Science & Technology

2016-05-26

that “hampered by 35 Bruce Menning, “Operational Art’s Origins,” in Historical Perspectives of the Operational Art, ed. Michael D. Krause and R. Cody...war or theater of 43 Clayton Newell, “Introduction,” in On Operational Art, ed. Clayton Newell and Michael Krause (Washington, DC: US Army Center of...Menning, Bruce. “Operational Art’s Origins.” In Historical Perspectives of the Operational Art, edited by Michael D. Krause and R. Cody Phillips, 3

Preparing Brigade Combat Team Soldiers for Mission Readiness Through Research on Intangible Psychological Constructs and their Applications: Validation and Pilot

DTIC Science & Technology

2015-01-01

and their Applications: Validation and Pilot Steven N. Aude Kenneth Nicely Michael A. Lodato ICF International Christopher L. Vowels...CONTRACT OR GRANT NUMBER W5J9CQ-11-0009 5b. PROGRAM ELEMENT NUMBER 622785 6. AUTHOR(S) Steven N. Aude, Kenneth Nicely, Michael A... Michael A. Lodato ICF International Christopher L. Vowels U.S. Army Research Institute Fort Hood Research Unit Brian T. Crabb

Gas Control and Thermal Modeling Methods for Pressed Pellet and Fast Rise Thin-Film Thermal Batteries

DTIC Science & Technology

2015-09-01

Thin-Film Thermal Batteries by Frank C Krieger and Michael S Ding Approved for public release; distribution unlimited...Laboratory Gas Control and Thermal Modeling Methods for Pressed Pellet and Fast Rise Thin-Film Thermal Batteries by Frank C Krieger and Michael S...Batteries 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Frank C Krieger and Michael S Ding 5d. PROJECT NUMBER

Production of a Novel OX40 Ligand for Clinical Use

DTIC Science & Technology

2012-10-01

inhibitory to the detection of mycoplasma. 19.0 TECHNICAL REFERENCES 19.1 Barile , Michael F. and McGarrity, Gerard J. (1983). "Isolation of Mycoplasmas from...Edition, Section 2.6.7, Mycoplasmas. 19.4 McGarrity, Gerard J. and Barile , Michael F. (1983). "Use of Indicator Cell Lines for Recovery and...test material will be discarded following study completion unless otherwise requested by Sponsor. 20.0 REFERENCES 20.1 Barile , Michael F. and

Magnetic Insulation in Coaxial Transmission Lines with an External Magnetic Field

DTIC Science & Technology

1980-03-13

A. Mostrom, Michael E. Jones, and Lester E. Thode SUBMITTED TO: Physical Review Letters March 13, 1980 SöKOK_Kä^MJ!L;; ÄgEie?©d tea gas &c...Number Assigned by Contract Monitor: SLL 81- 262 Comments on Document: Archive, RRI, DEW . From Physical Review Letters Descriptors, Keywords: Magnetic...Source of Document: DEW MAGNETIC INSULATION IN COAXIAL TRANSMISSION LINES WITH AN EXTERNAL MAGNETIC FIELD Michael A. Mostrom, Michael E. Jones, and

The Russo-Japanese War, Lessons Not Learned

DTIC Science & Technology

2003-05-06

USACGSC, August, 2002), CR3.7-1--CR3.7-14; Michael Howard , “Men Against Fire, Expectations of War in 1914,” International Security (Summer 1984): 41-57...169; Carl von Clausewitz, On War, trans. and ed. Michael Howard and Peter Paret (Princeton: Princeton University Press, 1984), 37-38. 8Service in...Cleator, P. Weapons of War. New York: Thomas Y. Crowell Company, 1967. Clausewitz, Carl von. On War. Edited and translated by Michael Howard and

Evaluating perceptions of the effectiveness of the community advisory panel model for enhancing service delivery to marginalized populations.

PubMed

Ramsay, Jason T; Smith, Peter; Thompson, Alison; O'Campo, Patricia; Nisenbaum, Rosane; Watson, Priya; Park-Wylie, Laura; Bryant, Toba; Tandon, Reena; Farah, Mohammed

2012-01-01

The objective of this study was to evaluate perceptions of the effectiveness of the community advisory panels (CAPs) at St. Michael's Hospital, in Toronto, Canada. A qualitative design was employed. Participants included hospital staff, patients, Community Advisory Panel chairs, and key informants from community services in the St. Michael's Hospital catchment area. An online survey about awareness of the CAPs and CAP accomplishments; (2) Key informants interviews; and (3) Review of memos and meeting minutes of the CAPs to assess their impact in the hospital and the community. St. Michael's Hospital was the setting of the study. Descriptive statistics were generated for the survey data. Qualitative interview data were coded for major themes. Participants included hospital staff, patients, CAP chairs, and key informants from community services in the St. Michael's Hospital catchment area. Although the CAPs initiated and implemented an array of programs and services at St. Michael's Hospital, the visibility of the CAPs and their service to the hospital and community were very low. Themes that emerged from the semistructured interviews involved the visibility, effectiveness, and role of the CAPs in the hospital. Although the CAPs at St. Michael's Hospital appear to be an effective model for community responsiveness, the visibility of their work in the hospital and community was very low. © 2012 Wiley Periodicals, Inc.

Chronicles.

ERIC Educational Resources Information Center

Dwyer, Judith A.; And Others

1984-01-01

Includes eight articles: Judith Dwyer and Francis Meehan on nuclear education for Catholic undergraduates; Kathy Greeley, Susan Markowitz, Carol Rank, Roberta Snow, and Lisa Goodman on high school curricula developed by peace organizations; Charlotte Watertow on global solutions; Michael Antrim on the science of nuclear energy; Frederick…

HIGHLY DIASTEREOSELECTIVE MICHAEL REACTION UNDER SOLVENT-FREE CONDITIONS USING MICROWAVES: CONJUGATE ADDITION OF FLAVANONE TO ITS CHALCONE PRECURSOR

EPA Science Inventory

Microwave-assisted reaction of 2'-hydroxychalcones in the presence of DBU resulted in the formation of hitherto unknown dimers by conjugate addition of the intermediate cyclic ketone to the starting enone.

Multi-User Spaceport Update News Conference

NASA Image and Video Library

2014-01-23

CAPE CANAVERAL, Fla. – Sierra Nevada Corporation, or SNC, Space Systems, announces the steps the company will take to prepare for a November 2016 orbital flight of its Dream Chaser spacecraft from Florida’s Space Coast during a news conference at NASA’s Kennedy Space Center in Florida. Participants are, from left, Michael Curie, NASA spokesman, Bob Cabana, director of Kennedy, Michael Gass, president and CEO of United Launch Alliance, or ULA, Frank DiBello, president and CEO of Space Florida, Mark Sirangelo, corporate vice president and head of SNC Space Systems, Larry Price, Lockheed Martin Space Systems deputy program manager for NASA's Orion spacecraft, and Steve Lindsey, Dream Chaser program manager for SNC Space Systems. The steps are considered substantial for SNC and important to plans by NASA and Space Florida for Kennedy’s transformation into a multi-user spaceport for both commercial and government customers. SNC said it plans to work with ULA to launch the Dream Chaser spacecraft into orbit atop an Atlas V rocket from Space Launch Complex 41 at Cape Canaveral Air Force Station intends to land the winged spacecraft at Kennedy’s 3.5-mile long runway at the Shuttle Landing Facility lease office space at Exploration Park, right outside Kennedy’s gates and process the spacecraft in the high bay of the Operations and Checkout Building at Kennedy, with Lockheed Martin performing the work. Photo credit: NASA/Kim Shiflett

Michael Griffin House Science Committee Hearing

NASA Image and Video Library

2005-06-27

NASA Administrator Michael Griffin prepares to testify at a hearing before the House Science Committee, Tuesday, June 28, 2005, Rayburn House Office building, Washington. Photo Credit: (NASA/Bill Ingalls)

Geophysicists

NASA Astrophysics Data System (ADS)

2004-06-01

In Memoriam: James R. Holton, Buford K. Meade, Mikhail I. Pudovkin; Honors: Michel Blanc, Alberto Borges, Paola Vannucchi, Michael A. Hapgood, Subir Banerjee, Lev Vinnik, John Wahr, Forrest Mozer, Vladimir N. Zharkov, Michael Ghil

Michael Griffin House Science Committee Hearing

NASA Image and Video Library

2005-06-27

Rep. Bart Gordon, D-TN., questions NASA Administrator Michael Griffin during a House Science Committee hearing, Tuesday, June 28, 2005, Rayburn House Office building, Washington. Photo Credit: (NASA/Bill Ingalls)

ASK Talks with Dr. Michael Hecht

NASA Technical Reports Server (NTRS)

Hecht, Michael

2003-01-01

Michael Hecht has been a member of NASA's Jet Propulsion Laboratory (JPL) staff since 1982. He is currently Project Manager and co-investigator for the Mars Environmental Compatibility Assessment (MECA)

Michael Thackeray on Lithium-air Batteries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thackeray, Michael

2009-01-01

Michael Thackeray, Distinguished Fellow at Argonne National Laboratory, speaks on the new technology Lithium-air batteries, which could potentially increase energy density by 5-10 times over lithium-ion batteries.

Michael Thackeray on Lithium-air Batteries

ScienceCinema

Thackeray, Michael

2018-02-06

Michael Thackeray, Distinguished Fellow at Argonne National Laboratory, speaks on the new technology Lithium-air batteries, which could potentially increase energy density by 5-10 times over lithium-ion batteries.

STS-114: Discovery Launch Readiness Press Conference

NASA Technical Reports Server (NTRS)

2005-01-01

Michael Griffin, NASA Administrator; Wayne Hale, Space Shuttle Deputy Program Manager; Mike Wetmore, Director of Shuttle Processing; and 1st Lieutenant Mindy Chavez, Launch Weather Officer-United States Air Force 45th Weather Squadron are in attendance for this STS-114 Discovery launch readiness press conference. The discussion begins with Wayne Hale bringing to the table a low level sensor device for everyone to view. He talks in detail about all of the extensive tests that were performed on these sensors and the completion of these ambient tests. Chavez presents her weather forecast for the launch day of July 26th 2005. Michael Griffin and Wayne Hale answer questions from the news media pertaining to the sensors and launch readiness. The video ends with footage of Pilot Jim Kelly and Commander Eileen Collins conducting test flights in a Shuttle Training Aircraft (STA) that simulates Space Shuttle landing.

STS-103 Photo-op/Suit-up/Depart O&C/Launch Discovery On-Orbit/Landing/Crew Egress

NASA Technical Reports Server (NTRS)

2001-01-01

The crew of the STS-103 space mission are shown as they prepare for launch and landing of the space shuttle discovery. The crew includes: Commander Curtis L. Brown, Pilot Scott J. Kelly, and Mission Specialists: Steven L. Smith, C. Michael Foale, John M. Grunsfeld, Claude Nicollier and Jean-francois Clervoy. Footage of these astronauts during suit-up, Ingress, Egress and Operations and Checkout (O&C) is presented. Live footage of the countdown and launch of the space shuttle discovery is shown from various vantage points such as the Tower 1, Vehicle Assembly Building (VAB), and pad perimeter. Once in orbit, a presentation of Steven Smith, John Grunsfield, Michael Foale and Claude Nicollier performing three spacewalks to repair the HST is shown. The landing of the space shuttle discovery at the Kenndy Space Center is shown.

Getting Ready

ERIC Educational Resources Information Center

Umphrey, Jan; Foran, Michael

2012-01-01

This article presents an interview with Michael Foran, the 2012 MetLife/NASSP National High School Principal of the Year. In the interview, Mr. Foran explains what it means to be a school leader and how it has influenced his work at New Britain (CT) High School. He also describes the ways he is working toward getting all students at New Britain…

Using adverse outcome pathway analysis to guide development of high-throughput screening assays for thyroid-disruptors

EPA Science Inventory

Using Adverse Outcome Pathway Analysis to Guide Development of High-Throughput Screening Assays for Thyroid-Disruptors Katie B. Paul1,2, Joan M. Hedge2, Daniel M. Rotroff4, Kevin M. Crofton4, Michael W. Hornung3, Steven O. Simmons2 1Oak Ridge Institute for Science Education Post...

Grafting-Density Effects, Optoelectrical Properties and Nano-Patterning of Poly(para-Phenylene) Brushes

DTIC Science & Technology

2013-01-01

NAME OF RESPONSIBLE PERSON 19b. TELEPHONE NUMBER S. Michael Kilbey Dawen Li, Jimmy W. Mays , S. Michael Kilbey II, Jihua Chen, Jose Alonzo, Xiang Yu...Dawen Li,d Jimmy W. Mays ,be Bobby G. Sumpteraf and S. Michael Kilbey II*eg Well-defined conjugated polymers in confined geometries are chal- lenging to...relationships of conned thin lms and may serve as a basis to understand polymer micelles, polymer-stabilized colloid particles, or interfaces compatibi

A Parametric Regression of the Cost of Base Realignment Action (COBRA) Model

DTIC Science & Technology

1993-09-20

Douglas D. Hardman , Captain, USAF Michael S. Nelson, Captain, USAF AFIT/GEE/ENS/93S-03 93 P’ 8 143 Approved for public release, distribution unlimited 93... Hardman CLASS: GEE 93S Captain Michael Nelson TITLE: A Parametric Regression of the Cost of Base Realignment Action (COBRA) Model DEFENSE DATE: 20...Science in Engineering and Environmental Management Douglas D. Hardman , B.S.E.E. Michael S. Nelson, B.S.C.E Captain, USAF Captain, USAF September 1993

Deception in Covert Nuclear Weapons Development: A Framework to Identify, Analyze, and Mitigate Future Long-Term Deception Efforts

DTIC Science & Technology

2016-03-01

In March, shortly after the BJP’s electoral victory, senior foreign policy advisor N . N . Jha informed U.S. embassy officials in New Delhi that the...College, 1998. Barker, Brian, Michael Clark, Peter Davis, Mark Fisk, Michael Hedlin, Hans Israelsson, Vitaly Khalturin, et al. "Monitoring Nuclear...Pretoria, South Africa, 1981. Mihalka, Michael, German Strategic Deception in the 1930’s, Santa Monica, Calif.: RAND Corporation, N -1557-NA, 1980

Michael Polanyi: Science as Personal Knowledge and Social Practice.

PubMed

Nye, Mary Jo

2017-03-20

Tacit knowing: 2016 marked the 125th anniversary of the birth of the physical chemist Michael Polanyi, as well as the 40th of his death. This essay discusses his philosophy of science-in particular, his most significant work in this area, Personal Knowledge-from the perspective of his personal biography, as well as its lasting influence on the social sciences. In the photograph: Michael Polanyi at the Fritz Haber Institute in 1968. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Proceedings, Conference and Training Workshop on Wildlife Hazards to Aircraft Held at Charleston, South Carolina on 22-25 May 1984

DTIC Science & Technology

1984-05-25

Aircraft ~.Aut@i~Michael J . Harrison/Sidney A. Gauthreaux, Jr., -Lilia A. Abron-Robinson .WeUi’N.(TiS 9. Pordoni,mg Ogon.m,t,. Nome and AdOda.0...Michael J . Harrison (AAS-330) 16. A4049ract , /-7hese proceedings were developed to enhance information exchange and improve understanding and control of...Wildlife Hazards to Aircraft S Conference and Training Workshop Edited by: Michael J . Harrison Federal Aviation Administration . Dr. Sidney A

Maniac Talk - Michael Kurylo

NASA Image and Video Library

2016-11-16

Michael Kurylo Maniac Lecture, November 16, 2016 NASA climate scientist Michael Kurylo presented a Maniac lecture entitled, "An Uncharted Journey: How I Became an Atmospheric Scientist Rather than a Cowboy or a Farmer." Mike described the path that took him from post-WW II housing projects to and through a rural Connecticut neighborhood, how he became convinced about the unrealistic nature of some early naive career dreams, and how he eventually arrived at a career in atmospheric science (research and program management, and their interface with international environmental policy).

"Anti-Michael addition" of Grignard reagents to sulfonylacetylenes: synthesis of alkynes.

PubMed

Esteban, Francisco; Boughani, Lazhar; García Ruano, José L; Fraile, Alberto; Alemán, José

2017-05-10

In this work, the addition of Grignard reagents to arylsulfonylacetylenes, which undergoes an "anti-Michael addition", resulting in their alkynylation under very mild conditions is described. The simplicity of the experimental procedure and the functional group tolerance are the main features of this methodology. This is an important advantage over the use of organolithium at -78 °C that we previously reported. Moreover, the synthesis of diynes and other examples showing functional group tolerance in this anti-Michael reaction is also presented.

Friction Drag Reduction Using Superhydrophobic Surface in High Reynolds Number Turbulent Flow

DTIC Science & Technology

2017-12-25

high Reynolds numbers by using the large towing tank available Naval Academy in Annapolis, in collaboration with Professor Michael...NAME(S) AND ADDRESS(ES) 12. DISTRIBUTION/ AVAILABILITY STATEMENT 13. SUPPLEMENTARY NOTES 14. ABSTRACT 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION... High Reynolds Number Turbulent Flow Smits, Alexander J Princeton University, Princeton, NJ 08544 N/A Office of Naval Research 875 N. Randolph Street

Airway Humidification During High-Frequency Percussive Ventilation

DTIC Science & Technology

2009-03-01

Airway Humidification During High-Frequency Percussive Ventilation Patrick F Allan MD, Michael J Hollingsworth CRT, Gordon C Maniere CRT, Anthony K...about the risk of inadequate humidification during high- frequency percussive ventilation (HFPV). METHODS: We studied 5 humidifiers during HFPV with a...50 L/min, and the ConchaTherm Hi-Flow with VDR nebulizer) provided carinal humidification equivalent to the comparator setup, without regard to

78 FR 4406 - Notice of Commission Staff Attendance

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-22

... Carolina Electric & Gas Company For more information, contact Michael Lee, Office of Energy Market Regulation, Federal Energy Regulatory Commission at (202) 502-8658 or Michael.Lee@ferc.gov . Dated: January...

Children Who Kill.

ERIC Educational Resources Information Center

Natale, Jo Anna

1999-01-01

Two recent books, "When Good Kids Kill," by Michael D. Kelleher, and "Lost Boys," by James Garbarino, explore how children become killers and suggest ways to reduce our high-pressure society's epidemic levels of youth violence. Physically or psychologically distant parents and unaffirmative media messages are negative…

Michael F. Crowley | NREL

Science.gov Websites

architectures. Crowlely's group has designed and implemented new methods and algorithms specifically for biomass , Crowley developed highly parallel methods for simulations of bio-macromolecules. Affiliated Research advanced sampling methods, Crowley and his team determine free energies such as binding of substrates

CfAO Fall Science Retreat 2017

Science.gov Websites

: Mark Chun, Astronomy Dept., U. Hawaii) Point Spread Function Reconstruction for AO Science (Organizer : Jessica Lu, Astronomy Dept., UC Berkeley) High Contrast Exoplanet Instrumentation Program for TMT (Organizer: Michael Fitzgerald, Astronomy Dept., UCLA) Special Plenary Session: TMT international training

"Feminist" Teaching/Teaching "Feminism"

ERIC Educational Resources Information Center

Carillo, Ellen C.

2007-01-01

The stakes are high for feminist teachers. Susan A. Basow, Nancy T. Silberg, Kathryn Duncan, Michael Stasio, and others have reported disturbing findings regarding the discrepancy between student evaluations of male professors and female professors. Professors who have identified themselves as feminists or committed to practicing feminist…

Electronic spreadsheet vs. manual payroll.

PubMed

Kiley, M M

1991-01-01

Medical groups with direct employees must employ someone or contract with a company to compute payroll, writes Michael Kiley, Ph.D., M.P.H. However, many medical groups, including small ones, own a personal or minicomputer to handle accounts receivable. Kiley explains, in detail, how this same computer and a spreadsheet program also can be used to perform payroll functions.

78 FR 77151 - Notice of Senior Executive Service Performance Review Board Appointments

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-20

... Scott Rodi, John L. Roessel, Charles M. Rosen, Diane K. Ross, John W. Roth, Barry N. Rountree, Carl D.... Barchenger, Ervin J Bathrick, Mark L. Bayani, Theresa Walsh Beall, James W. Bean, Michael J. Beaudreau, Tommy.... Blanchard, Mary Josie Boling, Edward A. Bolton, Hannibal Bowker, Bryan L. Broun, Laurence I. Brown, David W...

76 FR 70711 - Senior Executive Service; Performance Review Board

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-15

... BROWN, FRED L BROWN, STEPHANIE H BRUCE, SANDRA D BRYAN, PAUL F BRYAN, WILLIAM N BURROWS, CHARLES W... GEERNAERT, GERALD L GEISER, DAVID W GELLES, CHRISTINE M GENDRON, MARK O GERRARD, JOHN E GIBBS, ROBERT C... HOLLETT, DOUGLAS W HOLLRITH, JAMES W HORTON, LINDA L HOWARD, MICHAEL F HOWELL JR, J T HUIZENGA, DAVID G...

77 FR 65870 - Notice of Performance Review Board Membership

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-31

... listed below. Ackley, Victor Mr. Adams, Patricia A. Ms. Allard, Terry T. Dr. Andress, Mark Mr. Balderson.... Jabaley, Michael E. RDML Jaynes, CJ RDML Johnson, David C. RADM Jones, Walter F. Dr. Keeney, Carmela A. Ms.... McCurdy, Jesse W. Jr. Mr. Montgomery, John A. Dr. Moore, Thomas J. RDML Murdoch, James A RDML Murray...

Physiologic Basis for Understanding Quantitative Dehydration Assessment

DTIC Science & Technology

2012-01-01

Perspective Physiologic basis for understanding quantitative dehydration assessment1–4 Samuel N Cheuvront, Robert W Kenefick, Nisha Charkoudian, and...Michael N Sawka ABSTRACT Dehydration (body water deficit) is a physiologic state that can have profound implications for human health and performance...review the physiologic basis for understanding quantitative dehydration as- sessment. We highlight how phenomenologic interpretations of de- hydration

Education Reform and the Limits of Policy: Lessons from Michigan

ERIC Educational Resources Information Center

Addonizio, Michael F.; Kearney, C. Philip

2012-01-01

During the last 20 years, the United States has experienced more attempts at education reform than at any other time in its history. Efforts to reform financing, the assessment of student performance, accountability and equity, and school choice have all been implemented--with varying levels of success. Michael F. Addonizio and C. Philip Kearney…

Power and Leader Effectiveness in Organizations: A Literature Review

DTIC Science & Technology

2008-09-01

cinema and television as dramatic, memorable verbal reprimands for poor performance or an unaccomplished mission. However, coercive power does not...character played by Michael Keaton improved American automotive plant efficiency by improving working relations between the Japanese management and...attraction between the Japanese management and the American laborers. The relational benefits translated into happier employees that were more

The Embodiment of Social Dynamics: A Phenomenon of Western Pop Dance within a Filipino Prison

ERIC Educational Resources Information Center

Williams, Fleur Cathrael

2013-01-01

In January of 2010, in Cebu, a southern province of the Philippines, a collaborative dance performance occurred between 1500 Filipino inmates, the choreographer Travis Payne, and backup dancers representing the late American pop star, Michael Jackson. The event took place at Cebu Provincial Detention and Rehabilitation Centre, a maximum security…

Reliability-Growth Assessment, Prediction, and Control for Electronic Engine Control (GAPCEEC)

DTIC Science & Technology

1984-04-01

COMPEtTIN FOR Control (GAPCEEC) 4. PERFORMING ORG. REPORT NUMUR ______________________________ P&W/GPD/FR-17847 7. AUTI4OR(e) Michael E. McGlone...Control for Electronic Engine Control (GAPCEEC) program was performed under contract F33615-81 -C-2015. This 22-month program I. was formulated to study and...and (3) that data should be tracked c-ontinuously on an indiidual and fleet basis. UNCLASSIFIED 86CURITY CLASSIICATION OF THIS PAGErWmm Doe Rateio

Adaptive Role-Play Exercises for a Leader Development Center

DTIC Science & Technology

2006-11-01

OR GRANT NUMBER W91 FD3-06-P-0023 Adaptive Role-Play Exercises for a Leader Development Center 5b. PROGRAM ELEMENT NUMBER 665502 6. AUTHOR(S): 5c...PROJECT NUMBER M770 Michael Hertz (Progeny Systems Corporation) 5d. TASK NUMBER 103 5e. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS...ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Progeny Systems Corporation 9500 Innovation Drive Manassas, VA 20110 9. SPONSORING/MONITORING AGENCY NAME

Atmospheric Structure. Part 3. Upper Air and Surface Data: Stallion Site

DTIC Science & Technology

1975-01-01

Structure Part 3, Upper Air and Surface Data Stallion Site S. TYPE OF REPORT & PERIOD COVERED 6- PERFORMING ORG. REPORT NUMBER 7. AUTHORS...Marjorie M. Hoidale Michael P. Dayton Lamar Newman •. CONTRACT OR GRANT NUMBERS DA Task 1T665702D127-02 9. PERFORMING ORGANIZATION NAME AND ADORESS 10...Sciences Laboratory White Sands Missile Ran^e, New Mexico 12. REPORT DATE January 1975 13. NUMBER OF PAGES «Ä33 ; U MONITORING AGENCY NAME

Microfabricated Multianalyte Sensor Arrays for Metabolite Monitoring

DTIC Science & Technology

2005-09-01

Approved for Public Release; Distribution Unlimited The views, opinions and/or findings contained in this report are those of the author( s ) and should not...1-0780 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER Michael V. Pishko, Ph.D. 5e. TASK NUMBER 5f. WORK UNIT NUMBER E-mail: mpishkoc...engr.psu.edu 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Pennsylvania State University University Park, PA

The Ashore Infrastructure Requirments Needed to Support Mobile Maintenance Facilities (MMF) for Intermediate Maintenance on the Next Generation Aircraft Carrier (CVNX)

DTIC Science & Technology

1999-12-01

GENERATION AIRCRAFT CARRIER (CVNX) 6. AUTHOR(S) Watt, Michael R. 5. FUNDING NUMBERS Contract Number 7. PERFORMING ORGANIZATION NAME(S) AND...ADDRESS(ES) Naval Postgraduate School Monterey, CA 93943-5000 PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING / MONITORING AGENCY NAME(S) AND... ORGANIZATION OF STUDY 5 H. BACKGROUND INFORMATION 9 A. CURRENT MILITARY USERS OF MOBILE FACILITIES 10 1. United States Marine Corps (USMC) 11 2

Goddard Queen Visit

NASA Image and Video Library

2007-05-07

Prince Philip greets astronauts from STS-125 L to R Andrew J Feustel, Michael T Goode, K. Megan McArthur, Michael J. Massimino, Gregory C. Johnson, and Commander Scott D. Altman. Photo Credit: (NASA/Chris Gunn)

78 FR 36183 - Notice of Commission Staff Attendance

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-17

... Electric & Gas Company For More Information Contact: Michael Lee, Office of Energy Market Regulation, Federal Energy Regulatory Commission at (202) 502-8658 or Michael.Lee@ferc.gov . Dated: June 11, 2013...

Analysis of Multiple-Impact Ballistic Performance of a Tempered Glass Laminate with a Strike Face Film

DTIC Science & Technology

2014-02-01

a 0.18 in thick polymer interlayer between two layers of 0.5 in tempered silica based “ soda lime ” glass . A 0.08 in shatter resistant film was...AFCEC-CX-TY-TR-2014-0005 ANALYSIS OF MULTIPLE-IMPACT BALLISTIC PERFORMANCE OF A TEMPERED GLASS LAMINATE WITH A STRIKE FACE FILM Michael A. Magrini...Interim Technical Report 3 JAN 2012 to 2 JAN 2013 Analysis of Multiple-Impact Ballistic Performance of A Tempered Glass Laminate with a Strike Face Film

Michael Griffin House Science Committee Hearing

NASA Image and Video Library

2005-06-27

Members of the media photograph NASA Administrator Michael Griffin as he testifies at a hearing before the House Science Committee, Tuesday, June 28, 2005, Rayburn House Office building, Washington. Photo Credit: (NASA/Bill Ingalls)

Michael Lawson | NREL

Science.gov Websites

NREL's Ocean Energy team, Dr. Michael Lawson focuses on the areas of wave and water current energy goal of developing an open source design and analysis tool for wave energy conversion (WEC) devices

Transportation

DTIC Science & Technology

2006-01-01

Ports. Logistics Today, Vol.46. Issue 9. 43. Maloni, Michael ., Jackson , Eric. (2005, Spring). North American Container Port Capacity: A...Literature Review. Transportation Journal, Spring 2005. 16-36. Maloni, Michael ., Jackson , Eric. (2005, Summer). North American Container Port Capacity: An

Synthesis and stereochemical analysis of β-nitromethane substituted γ-amino acids and peptides.

PubMed

Ganesh Kumar, Mothukuri; Mali, Sachitanand M; Gopi, Hosahudya N

2013-02-07

The high diastereoselectivity in the Michael addition of nitromethane to α,β-unsaturated γ-amino esters, crystal conformations of β-nitromethane substituted γ-amino acids and peptides are studied. Results suggest that the N-Boc protected amide NH, conformations of α,β-unsaturated γ-amino esters and alkyl side chains play a crucial role in dictating the high diastereoselectivity of nitromethane addition to E-vinylogous amino esters. Investigation of the crystal conformations of both α,β-unsaturated γ-amino esters and the Michael addition products suggests that an H-C(γ)-C(β)=C(α) eclipsed conformer of the unsaturated amino ester leads to the major (anti) product compared to that of an N-C(γ)-C(β)=C(α) eclipsed conformer. The major diastereomers were separated and subjected to the peptide synthesis. The single crystal analysis of the dipeptide containing β-nitromethane substituted γ-amino acids reveals a helical type of folded conformation with an isolated H-bond involving a nine-atom pseudocycle.

Lewis acid-Lewis acid heterobimetallic cooperative catalysis: mechanistic studies and application in enantioselective aza-Michael reaction.

PubMed

Yamagiwa, Noriyuki; Qin, Hongbo; Matsunaga, Shigeki; Shibasaki, Masakatsu

2005-09-28

The full details of a catalytic asymmetric aza-Michael reaction of methoxylamine promoted by rare earth-alkali metal heterobimetallic complexes are described, demonstrating the effectiveness of Lewis acid-Lewis acid cooperative catalysis. First, enones were used as substrates, and the 1,4-adducts were obtained in good yield (57-98%) and high ee (81-96%). Catalyst loading was successfully reduced to 0.3-3 mol % with enones. To broaden the substrate scope of the reaction to carboxylic acid derivatives, alpha,beta-unsaturated N-acylpyrroles were used as monodentate, carboxylic acid derivatives. With beta-alkyl-substituted N-acylpyrroles, the reaction proceeded smoothly and the products were obtained in high yield and good ee. Transformation of the 1,4-adducts from enones and alpha,beta-unsaturated N-acylpyrroles afforded corresponding chiral aziridines and beta-amino acids. Detailed mechanistic studies, including kinetics, NMR analysis, nonlinear effects, and rare earth metal effects, are also described. The Lewis acid-Lewis acid cooperative mechanism, including the substrate coordination mode, is discussed in detail.

Meet EPA Scientist Michael Nye, Ph.D.

EPA Pesticide Factsheets

Michael Nye, Ph.D., is a social scientist who studies natural risk, socio-demographic change and sustainable behavior. Prior to joining EPA, he worked for the UK Environment Agency in flood risk management and emergency preparedness

High Power Microwaves on the Future Battlefield: Implications for U.S. Defense

DTIC Science & Technology

2010-02-17

Group, 2007), Chapters 7-10, and Steven H. Gold, Gregory S . Nusinovich, “Review of High - Power Microwave Source Research,” Review of Scientific...Edl Schamiloglu. High Power Microwaves. 2nd ed. Boca Raton, FL: CRC Press, Taylor and Francis Group, 2007. Bertin, Michael S . “Critical Directed...Gold, Steven H., Gregory S . Nusinovich. “Review of High - Power Microwave Source Research.” Review of Scientific Instruments 68, no. 11 (November

Biennial Guidance Test Symposium (16th) Held in Holloman Air Force Base, New Mexico on October 5-7, 1993. Volume 1

DTIC Science & Technology

1993-10-01

Michael Swamp, Contraves Inc., Pittsburgh PA; Dr. Michael D. Hooser, CIGTF, Holloman AFB NM Hig h Stability Large Centrifuge Test Bed 305 Dr. Louis A...DeMore, Robert Anticole, and Hans Riggenbach, Contraves Inc, Pittsburgh PA; Dr. Michael D. Hooser, CIGTF, Holloman AFB NM vi SESSION V-A: WEAPONS...power spectral density of input are also frozen out, allowing very low loss referred noise) of 10’ HzŖ below 100 Hz. springs. The input coils are

Reading Queer Counter-Narratives in the High-School Literature Classroom: Possibilities and Challenges

ERIC Educational Resources Information Center

Helmer, Kirsten

2016-01-01

Drawing on an ethnographic case study of a 13-week Gay and Lesbian Literature course, this paper explores how a high-school teacher and her students engaged with queer-themed literature. Focused on episodes around the class' engagement with two of the novels read in the course--Rita Mae Brown's "Rubyfruit Jungle" and Michael Cunningham's…

Combining Facial Recognition, Automatic License Plate Readers and Closed Circuit Television to Create an Interstate Identification System for Wanted Subjects

DTIC Science & Technology

2015-12-01

IPSFRP search request. The candidate list will contain the agency’s requested number (minimum of2) of candidates or a default number of 20 candidates if...INTERSTATE IDENTIFICATION SYSTEM FOR WANTED SUBJECTS 5. FUNDING NUMBERS 6. AUTHOR(S) Michael J. Thomas 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES...Naval Postgraduate School Monterey, CA 93943-5000 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING /MONITORING AGENCY NAME(S) AND

Foale performs FOOT experiment OPS in the U.S. Lab during Expedition 8

NASA Image and Video Library

2004-04-07

ISS008-E-20901 (7 April 2004) --- Astronaut C. Michael Foale, Expedition 8 commander and NASA ISS science officer, balances on the footplate of a special track attached to the Human Research Facility (HRF) rack in the Destiny laboratory on the International Space Station (ISS) to perform Foot/Ground Reaction Forces During Spaceflight (FOOT) / Electromyography (EMG) calibration operations. Foale is wearing the Lower Extremity Monitoring Suit (LEMS), the cycling tights outfitted with 20 sensors, which measures forces on joints and muscle activity.

Book review: Black bass diversity: Multidisciplinary science for conservation

USGS Publications Warehouse

Jelks, Howard L.

2016-01-01

Review info: Black bass diversity: Multidisciplinary science for conservation. Edited by Michael D. Tringali, James M. Long, Timothy W. Birdsong, and Michael S. Allen, 2015. ISBN: 978-1-934874-40-0, 685 pp.

MIDWEST STRUCTURAL SCIENCES CENTER 2011 ANNUAL REPORT

DTIC Science & Technology

2011-10-01

S. MICHAEL SPOTTSWOOD MICHAEL J. SHEPARD , Chief Senior Aerospace Engineer Analytical Mechanics Branch Analytical...49th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics & Materials Confe- rence, Chicago , IL, Apr. 7-10, 2008. AIAA 2008-2077. Efstathiou C

76 FR 25378 - Arts and Artifacts Indemnity Panel Advisory; Committee

Federal Register 2010, 2011, 2012, 2013, 2014

2011-05-04

... Officer, Michael McDonald, 1100 Pennsylvania Avenue, NW., Washington, DC 20506, or call 202/606-8322. Michael P. McDonald, Management Officer, Advisory Committee. [FR Doc. 2011-10789 Filed 5-3-11; 8:45 am...

Michael Akam and the rise of evolutionary developmental biology

PubMed Central

Stern, David L.; Dawes-Hoang, Rachel E.

2010-01-01

Michael Akam has been awarded the 2007 Kowalevsky medal for his many research accomplishments in the area of evolutionary developmental biology. We highlight three tributaries of Michael’s contribution to evolutionary developmental biology. First, he has made major contributions to our understanding of development of the fruit fly, Drosophila melanogaster. Second, he has maintained a consistent focus on several key problems in evolutionary developmental biology, including the evolving role of Hox genes in arthropods and, more recently, the evolution of segmentation mechanisms. Third, Michael has written a series of influential reviews that have integrated progress in developmental biology into an evolutionary perspective. Michael has also made a large impact on the field through his effective mentorship style, his selfless promotion of younger colleagues, and his leadership of the University Museum of Zoology at Cambridge and the European community of evolutionary developmental biologists. PMID:20209429

Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 3: Michael addition reactions and miscellaneous transformations.

PubMed

Aceña, José Luis; Sorochinsky, Alexander E; Soloshonok, Vadim

2014-09-01

The major goal of this review is a critical discussion of the literature data on asymmetric synthesis of α-amino acids via Michael addition reactions involving Ni(II)-complexes of amino acids. The material covered is divided into two conceptually different groups dealing with applications of: (a) Ni(II)-complexes of glycine as C-nucleophiles and (b) Ni(II)-complexes of dehydroalanine as Michael acceptors. The first group is significantly larger and consequently subdivided into four chapters based on the source of stereocontrolling element. Thus, a chiral auxiliary can be used as a part of nucleophilic glycine Ni(II) complex, Michael acceptor or both, leading to the conditions of matching vs. mismatching stereochemical preferences. The particular focus of the review is made on the practical aspects of the methodology under discussion and mechanistic considerations.

CDRA Valve RR

NASA Image and Video Library

2013-10-28

ISS037-E-021962 (28 Oct. 2013) --- NASA astronaut Michael Hopkins, Expedition 37 flight engineer, performs routine in-flight maintenance within the Carbon Dioxide Removal Assembly in the International Space Station?s Tranquility node. This device removes carbon dioxide from the station?s atmosphere and is part of the station?s Environmental Control and Life Support System that provides clean water and air to the crew.

Drugs in the Workplace: Research and Evaluation Data. Volume II. Research Monograph 100.

ERIC Educational Resources Information Center

Gust, Steven W., Ed.; And Others

This monograph presents 14 articles on the topics of the nature and extent of drug use by the workforce; drug use and job performance indicators; and drug free workplace program research. These articles are included: (1) Research on Drugs and the Workplace: Introduction and Summary (Steven Gust, Dennis Crouch, J. Michael Walsh); (2) Drug Use…

Foale performs potable water analysis OPS in the SM during Expedition 8

NASA Image and Video Library

2003-11-07

ISS008-E-05553 (7 November 2003) --- Astronaut C. Michael Foale, Expedition 8 mission commander and NASA ISS science officer, floats in front of the galley in the Zvezda Service Module on the International Space Station (ISS) as he fills a Crew Healthcare System (CheCSS) Water Microbiology (WMK) in-flight analysis bag from the potable warter dispenser.

CSP - Hyperspectral Imaging and Sounding of the Environment Meeting Scholarship Fund

DTIC Science & Technology

2017-05-09

performance via adaptation to the environment. The meeting has also contributed to the focus area of Electromagnetic Maneuver Warfare through disseminating the...latest information about advanced sensing techniques and understanding the electromagnetic environment through sensing. Additional sessions on...across the electromagnetic spectrum. The attendees at this event from the Naval Research Enterprise were Dr. Michael Yetzbacher, as a Program Co

Educating for Landpower

DTIC Science & Technology

2009-03-23

UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Captain Albert Lord Department of Military Strategy, Planning, and Operations 8...RESEARCH PROJECT EDUCATING FOR LANDPOWER by Lieutenant Colonel Michael S. Lewis United States Army Captain Albert Lord Project Adviser This SRP is...Napoleon ler; Publiee par ordre de l’empereur Napoleon III, 1858-1869, [Herafter Correspondance.], III, 2392 “Au President de L’Institut National [ Camus

MS Massimino and Newman on middeck after EVA 2

NASA Image and Video Library

2002-03-05

STS109-E-5643 (5 March 2002) --- Astronauts Michael J. Massimino (left) and James H. Newman, mission specialists, are back on board the mid deck of the Space Shuttle Columbia during the second of five scheduled STS-109 space walks to perform servicing and upgrading of the Hubble Space Telescope (HST). The image was recorded with a digital still camera.

Probing the Reactivity of Dimethylsulfoxonium Methylide with Conjugated and Nonconjugated Carbonyl Compounds: An Undergraduate Experiment Combining Synthesis, Spectral Analysis, and Mechanistic Discovery

ERIC Educational Resources Information Center

Ciaccio, James A.; Guevara, Elena L.; Alam, Rabeka; D'agrosa, Christina D.

2010-01-01

We introduce students to dimethylsulfoxonium methylide (DMSY) epoxidation of aryl and nonconjugated aliphatic aldehydes and ketones without revealing that DMSY cyclopropanates enones by Michael-initiated ring closure (MIRC). Each student performs the reaction of DMSY with one of nine carbonyl compounds, including four enones, and then analyzes the…

Michael Griffin | NREL

Science.gov Websites

production of high-value products Physical and chemical material characterization under reaction conditions Heterogeneous catalysis Design and operation of reactor systems Analysis of reaction kinetics and mechanisms labeled "major reaction products" at the top. On the right is a figure of blue spheres with a

Educational Entrepreneurship Today

ERIC Educational Resources Information Center

Hess, Frederick M., Ed.; McShane, Michael Q., Ed.

2016-01-01

In "Educational Entrepreneurship Today", Frederick M. Hess and Michael Q. McShane assemble a diverse lineup of high-profile contributors to examine the contexts in which new initiatives in education are taking shape. They inquire into the impact of entrepreneurship on the larger field--including the development and deployment of new…

Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418.

PubMed

Maucher, Isabelle V; Rühl, Michael; Kretschmer, Simon B M; Hofmann, Bettina; Kühn, Benjamin; Fettel, Jasmin; Vogel, Anja; Flügel, Karsten T; Manolikakes, Georg; Hellmuth, Nadine; Häfner, Ann-Kathrin; Golghalyani, Vahid; Ball, Ann-Katrin; Piesche, Matthias; Matrone, Carmela; Geisslinger, Gerd; Parnham, Michael J; Karas, Michael; Steinhilber, Dieter; Roos, Jessica; Maier, Thorsten J

2017-02-01

Recently, we published that nitro-fatty acids (NFA) are potent electrophilic molecules which inhibit 5-lipoxygenase (5-LO) by interacting catalytically with cysteine residues next to a substrate entry channel. The electrophilicity is derived from an intramolecular Michael acceptor moiety consisting of an electron-withdrawing group in close proximity to a double bond. The potential of the Michael acceptor moiety to interact with functionally relevant cysteines of proteins potentially renders them effective and sustained enzyme activity modulators. We screened a large library of naturally derived and synthetic electrophilic compounds to investigate whether other types of Michael acceptor containing drugs suppress 5-LO enzyme activity. The activity was measured by assessing the effect on the 5-LO product formation of intact human polymorphonuclear leukocytes. We demonstrated that a number of structurally different compounds were suppressive in the activity assays and showed that Michael acceptors of the quinone and nitro-alkene group produced the strongest inhibition of 5-LO product formation. Reactivity with the catalytically relevant cysteines 416 and 418 was confirmed using mutated recombinant 5-LO and mass spectrometric analysis (MALDI-MS). In the present study, we show for the first time that a number of well-recognized naturally occurring or synthetic anti-inflammatory compounds carrying a Michael acceptor, such as thymoquinone (TQ), the paracetamol metabolite NAPQI, the 5-LO inhibitor AA-861, and bardoxolone methyl (also known as RTA 402 or CDDO-methyl ester) are direct covalent 5-LO enzyme inhibitors that target the catalytically relevant cysteines 416 and 418. Copyright © 2016 Elsevier Inc. All rights reserved.

Michael Griffin Oath Of Office

NASA Image and Video Library

2005-04-14

John H. Marburger, Science Adviser to the President and Director of the Office of Science and Technology Policy (OSTP), left, shakes hands with NASA Administrator Michael Griffin following his swearing-in, Thursday, April 14, 2005, in Washington. Photo Credit: (NASA/Renee Bouchard)

Midwest Structural Sciences Center 2010 Annual Report

DTIC Science & Technology

2011-06-01

S. MICHAEL SPOTTSWOOD MICHAEL J. SHEPARD , Chief Senior Aerospace Engineer Analytical Mechanics Branch Analytical Mechanics Branch Structures...Structural Dynamics & Materials Confe- rence, Chicago , IL, Apr. 7-10, 2008. AIAA 2008-2077. Efstathiou C., Carroll J., Sehitoglu H., Lambros J

Specification Technology Guidebook.

DTIC Science & Technology

1985-08-01

1. General Aspects A. Identification JSD - Jackson System Development -. Michael Jackson Systems Limited 17 Conduit Street London, England WIROTD Tel...USER MANAGER ORGANIZATION ə X _ _ _ _ 1-3__ 3-6 X > 6 _ _ D. Primary Source of Document ation Michael Jackson Systems Limited Also see: References

Mapping the 2017 Eclipse: Education, Navigation, Inspiration

NASA Astrophysics Data System (ADS)

Zeiler, M.

2015-12-01

Eclipse maps are a unique vessel of knowledge. At a glance, they communicate the essential knowledge of where and when to successfully view a total eclipse of the sun. An eclipse map also provides detailed knowledge of eclipse circumstances superimposed on the highway system for optimal navigation, especially in the event that weather forces relocation. Eclipse maps are also a vital planning tool for solar physicists and astrophotographers capturing high-resolution imagery of the solar corona. Michael Zeiler will speak to the role of eclipse maps in educating the American public and inspiring people to make the effort to reach the path of totality for the sight of a lifetime. Michael will review the role of eclipse maps in astronomical research and discuss a project under development, the 2017 Eclipse Atlas for smartphones, tablets, and desktop computers.

Synthesis of ω-Oxo Amino Acids and trans-5-Substituted Proline Derivatives Using Cross-Metathesis of Unsaturated Amino Acids.

PubMed

Salih, Nabaz; Adams, Harry; Jackson, Richard F W

2016-09-16

A range of 7-oxo, 8-oxo, and 9-oxo amino acids, analogues of 8-oxo-2-aminodecanoic acid, one of the key components of the cyclic tetrapeptide apicidin, have been prepared by a three-step process involving copper-catalyzed allylation of serine-, aspartic acid-, and glutamic acid-derived organozinc reagents, followed by cross-metathesis of the resulting terminal alkenes with unsaturated ketones and hydrogenation. The intermediate 7-oxo-5-enones underwent a highly diastereoselective (dr ≥96:4) acid-catalyzed aza-Michael reaction to give trans-2,5-disubstituted pyrrolidines, 5-substituted proline derivatives. The aza-Michael reaction was first observed when the starting enones were allowed to stand in solution in deuterochloroform but can be efficiently promoted by catalytic amounts of dry HCl.

China in Space: Implications for U.S. Military Strategy

DTIC Science & Technology

2007-01-01

driver. The space program provides a mechanism for research and scientific exploration that will undoubtedly advance China’s education and high...ndu.edu/ login?url=http://proquest.umi.com/pqdweb?did= 1144517361&Fmt=3&clientId=3921&RQT=309&V Name=PQD>. 4 Michael Westlake, “Space program engen

Combining silver- and organocatalysis: an enantioselective sequential catalytic approach towards pyrano-annulated pyrazoles.

PubMed

Hack, Daniel; Chauhan, Pankaj; Deckers, Kristina; Mizutani, Yusuke; Raabe, Gerhard; Enders, Dieter

2015-02-11

A one-pot asymmetric Michael addition/hydroalkoxylation sequence, catalyzed by a sequential catalytic system consisting of a squaramide and a silver salt, provides a new series of chiral pyrano-annulated pyrazole derivatives in excellent yields (up to 95%) and high enantioselectivities (up to 97% ee).

Global Education Reform: How Privatization and Public Investment Influence Education Outcomes

ERIC Educational Resources Information Center

Adamson, Frank, Ed.; Astrand, Bjorn, Ed.; Darling-Hammond, Linda, Ed.

2016-01-01

With contributions from Linda Darling-Hammond, Michael Fullan, Pasi Sahlberg, and Martin Carnoy, "Global Education Reform" is an eye-opening analysis of national educational reforms and the types of high-achieving systems needed to serve all students equitably.The collection documents the ideologically and educationally distinctive…

Columbine Author Speaks at Conference

ERIC Educational Resources Information Center

Cook, Andrea J.

2004-01-01

Brooks Brown, the author of No Easy Answers: The Truth Behind Death at Columbine High School, spoke at the 11th annual Reclaiming Youth International No Disposable Kids conference at Rushmore Plaza Holiday Inn. Brown, who worked with Michael Moore on his Academy Award winning documentary, "Bowling for Columbine," said the letters he…

Beat the High Co$t of College

ERIC Educational Resources Information Center

Dolan, Thomas G.

2004-01-01

Students face financial challenges in acquiring higher education. According to Michael P. Viollt, president of Chicago's Robert Morris College, there are three mutually reinforcing problems: (1) the higher demands the society places for people to be educated; (2) rapidly decreasing government funding for financial aid; and (3) the perception of…

Nano-organocatalyst: Magnetically retrievable ferrite-anchored glutathione for microwave-assisted Paal-Knorr reaction, Aza-Michael addition and pyrazole synthesis

EPA Science Inventory

Postsynthetic surface modification of magnetic nanoparticles by glutathione imparts desirable chemical functionality and enables the generation of catalytic sites on the surfaces of ensuing organocatalysts. In this article, we discuss the developments, unique activity and high s...

76 FR 52697 - Meetings of Humanities Panel

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-23

...., Washington, DC 20506. FOR FURTHER INFORMATION CONTACT: Michael P. McDonald, Advisory Committee Management... subsections (c)(4), and (6) of section 552b of Title 5, United States Code. 1. Date: September 7, 2011. Time... Initiatives at Historically Black Colleges and Universities, High Hispanic Enrollment, and Tribal Colleges and...

A strategy for the generation, characterization and distribution of animal models by The Michael J. Fox Foundation for Parkinson's Research.

PubMed

Baptista, Marco A S; Dave, Kuldip D; Sheth, Niketa P; De Silva, Shehan N; Carlson, Kirsten M; Aziz, Yasmin N; Fiske, Brian K; Sherer, Todd B; Frasier, Mark A

2013-11-01

Progress in Parkinson's disease (PD) research and therapeutic development is hindered by many challenges, including a need for robust preclinical animal models. Limited availability of these tools is due to technical hurdles, patent issues, licensing restrictions and the high costs associated with generating and distributing these animal models. Furthermore, the lack of standardization of phenotypic characterization and use of varying methodologies has made it difficult to compare outcome measures across laboratories. In response, The Michael J. Fox Foundation for Parkinson's Research (MJFF) is directly sponsoring the generation, characterization and distribution of preclinical rodent models, enabling increased access to these crucial tools in order to accelerate PD research. To date, MJFF has initiated and funded the generation of 30 different models, which include transgenic or knockout models of PD-relevant genes such as Park1 (also known as Park4 and SNCA), Park8 (LRRK2), Park7 (DJ-1), Park6 (PINK1), Park2 (Parkin), VPS35, EiF4G1 and GBA. The phenotypic characterization of these animals is performed in a uniform and streamlined manner at independent contract research organizations. Finally, MJFF created a central repository at The Jackson Laboratory (JAX) that houses both non-MJFF and MJFF-generated preclinical animal models. Funding from MJFF, which subsidizes the costs involved in transfer, rederivation and colony expansion, has directly resulted in over 2500 rodents being distributed to the PD community for research use.

33 CFR 110.173 - Port of Charleston, SC.

Code of Federal Regulations, 2010 CFR

2010-07-01

... located 1800 yards, 118° true from St. Michaels Church Spire and has a diameter of 500 yards. Vessels...°30′ true, 1375 yards from St. Michaels Church Spire and has a diameter of 1400 feet. The use of this...

Operational Leadership in Kosovo

DTIC Science & Technology

2004-02-09

ARRC) LGEN Michael Jackson Allied Air Forces North (COMAIRNORTH) GEN John Jumper Allied Naval Forces North (COMNAVNORTH) U.K. Allied Naval Forces South... Michael Jackson reportedly told the US commander (Clark) during one heated exchange. When General Jackson refused, General Clark asked Admiral James

Michael Tomasello: Award for Distinguished Scientific Contributions.

PubMed

2015-11-01

The APA Awards for Distinguished Scientific Contributions are presented to persons who, in the opinion of the Committee on Scientific Awards, have made distinguished theoretical or empirical contributions to basic research in psychology. One of the 2015 award winners is Michael Tomasello, who received this award for "outstanding empirical and theoretical contributions to understanding what makes the human mind unique. Michael Tomasello's pioneering research on the origins of social cognition has led to revolutionary insights in both developmental psychology and primate cognition." Tomasello's award citation, biography, and a selected bibliography are presented here. (c) 2015 APA, all rights reserved).

Ontology Performance Profiling and Model Examination: First Steps

NASA Astrophysics Data System (ADS)

Wang, Taowei David; Parsia, Bijan

"[Reasoner] performance can be scary, so much so, that we cannot deploy the technology in our products." - Michael Shepard. What are typical OWL users to do when their favorite reasoner never seems to return? In this paper, we present our first steps considering this problem. We describe the challenges and our approach, and present a prototype tool to help users identify reasoner performance bottlenecks with respect to their ontologies. We then describe 4 case studies on synthetic and real-world ontologies. While the anecdotal evidence suggests that the service can be useful for both ontology developers and reasoner implementors, much more is desired.

77 FR 20820 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-06

... Trust, and Gloria Foley, all of Lovington, Illinois, and Paul Michael Hrvol, Jr. and Paul Michael Hrvol... Bancorp, Inc. and thereby indirectly control Hardware State Bank, both of Lovington, Illinois. Board of...

MICHAEL "RUDI" RUDOLPHI SPEAKING AT MISSION SUCCESS FORUM

NASA Image and Video Library

2016-06-16

MICHAEL "RUDI" RUDOLPHI GESTURES DURING A "MISSION SUCCESS IS IN OUR HANDS" SHARED EXPERIENCES FORUM JUNE 16, WHERE HE SPOKE ABOUT HIS "UNFORGETTABLE" EXPERIENCES AS A SENIOR NASA REPRESENTATIVE OVERSEEING DEBRIS RECOVERY EFFORTS FOLLOWING THE LOSS OF SPACE SHUTTLE COLUMBIA AND ITS CREW.

Michael Griffin Meets with Elon Musk

NASA Image and Video Library

2005-04-19

NASA Administrator Michael Griffin, left, meets with CEO of SpaceX Elon Musk, right, Wednesday, April 20, 2005 at NASA Headquarters in Washington. Looking on in the background are Larry Williams, NASA astronaut Marsha Ivins and NASA manager Christopher Shank. Photo Credit: (NASA/Renee Bouchard)

A Perspective on Research Challenges in Information Security

DTIC Science & Technology

2011-11-01

UNCLASSIFIED A Perspective on Research Challenges in Information Security Tamas Abraham, David Adie, Angela Billard, Paul Buckland, Michael Frangos ...Abstract (U) 4. AUTHORS Tamas Abraham, David Adie, Angela Billard, Paul Buckland, Michael Frangos , Ben Long, Mar- tin Lucas, Paul Montague, Dean Philp

Astronaut Michael Clifford takes a break during bailout training

NASA Technical Reports Server (NTRS)

1993-01-01

Astronaut Michael R.U. (Rich) Clifford takes a break while video taping crew mates in training in the JSC Weightless Environment Training Facility (WETF). He is pictured with Trent G. Keeple, a member of the training staff assigned to STS-59.

The Northern Ireland Framework for Peace: Terrorism and its Aftermath

DTIC Science & Technology

2012-04-10

Manchester University Press, 2000. Crawshaw , Colonel (Retd) Michael. The Evolution of British COIN. Joint Doctrine Publication 3-40: 19...Margaret E. McGuinness (Maryland: Rowman & Littlefield, 2000), 206. 35 Colonel (Retd) Michael Crawshaw , “The Evolution of British COIN”. Joint

Meet EPA Ecologist Michael Murrell, Ph.D.

EPA Pesticide Factsheets

Michael Murrel, Ph.D., is a EPA research ecologist working on the Gulf of Mexico Hypoxia Project, helping develop models of the northern Gulf to quantify the links between freshwater flowing into the Gulf from the land, nutrients, and hypoxia—“dead zones”

Medical Command in the Contingency Force

DTIC Science & Technology

1992-04-15

briefing. 36. Foust, interview. 37. Interviews with Michael J. Kussman , Carlisle, PA, 10 December 1991 and 5 February 1992. 38. Timboe, interview. 39... Kussman , Michael J., Internal Medicine Consultant to the Army Surgeon General, Office of Medical Corps Affairs, 1989-91. Interviews by author, 10

STS-34 Pilot Michael J. McCulley uses ARRIFLEX camera equipment

NASA Image and Video Library

1989-04-13

STS-34 Atlantis, Orbiter Vehicle (OV) 104, Pilot Michael J. McCulley squints while looking through ARRIFLEX camera eye piece during camera briefing at JSC. McCulley rests part of the camera on his shoulder as he operates it.

Michael Sadler and the German Connection.

ERIC Educational Resources Information Center

Higginson, J. H.

1990-01-01

Chronicles works of Michael Sadler who compared British and German educational systems, emphasizing Germany's contributions in technical education. Presents Sadler's 1912 recommendations--eight lessons premised upon powerful centralized government's ability to implement policy. Reflects on how World War I and Nazism influenced Sadler's thought and…

Michael F. Vaccaro Honors Attorney Fellowship Program in our Philadelphia (Region 3) Office

EPA Pesticide Factsheets

The Michael F. Vaccaro Honors Attorney Fellowship provides a unique opportunity to practice law in a major governmental environmental organization, and to receive extensive training in and exposure to environmental law and policy work in the public sector.

Enantioselective Michael Addition of Pyrroles with Nitroalkenes in Aqueous Media Catalyzed by a Water-soluble Catalyst.

PubMed

Gui, Yang; Li, Yanan; Sun, Jianan; Zha, Zhenggen; Wang, Zhiyong

2018-06-11

A new water-soluble catalytic system were developed and therefor used in an enantioselective Michael addition of pyrroles with nitroalkenes in water to afford the nitroethylpyrrole derivatives with both excellent yields and ee values.

Michael Griffin Senate Hearing

NASA Image and Video Library

2005-05-17

NASA Administrator Dr. Michael Griffin speaks in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

Official Portrait of Astronaut Michael Collins

NASA Technical Reports Server (NTRS)

1967-01-01

This is the official NASA portrait of astronaut Michael Collins. Collins chose an Air Force career following graduation from West Point. He served as an experimental flight test officer at the Air Force Flight Test Center, Edwards Air Force Base, California, and, in that capacity, tested performance and stability and control characteristics of Air Force aircraft, primarily jet fighters. Having logged approximately 5,000 hours flying time, Collins was one of the third group of astronauts named by NASA in October 1963. Collins completed two space flights, logging 266 hours in space, of which, 1 hour and 27 minutes was spent in Extra Vehicular Activity (EVA). On July 18, 1966, he served as backup pilot for the Gemini VII mission which included a successful rendezvous and docking with a separately launched Agena target vehicle and, using the power of the Agena, maneuvered the Gemini spacecraft into another orbit for a rendezvous with a second, passive Agena. His skillful performance in completing two periods of EVA included the recovery of a micrometeorite detection experiment from the passive Agena. July 16-24, 1969, Collins served as command module (CM) pilot on Apollo 11, the historic first lunar landing mission. He remained aboard the CM, Columbia, on station in lunar orbit and performed the final re-docking maneuvers following a successful lunar orbit rendezvous with the Lunar Module (LM), Eagle. Collins left NASA in January 1970.

STS-73 Flight Day 5

NASA Technical Reports Server (NTRS)

1995-01-01

On this fifth day of the STS-73 sixteen day mission, the crew Cmdr. Kenneth Bowersox, Pilot Kent Rominger, Payload Specialists Albert Sacco and Fred Leslie, and Mission Specialists Kathryn Thornton, Catherine 'Cady' Coleman, and Michael Lopez-Alegria are shown performing several of the spaceborne experiments onboard the United States Microgravity Lab-2 (USML-2). These experiments are downlinked to Mission Control from the Spacelab using the High-Packed Digital Television (HI-PAC) systems onboard the Shuttle. The experiments shown include the Drop Physics Module (DPM) experiment, the Surface Tension Driven Convection Experiment (STDCE), the Protein Crystal Growth (PCG) experiment, and a Hand-Held Diffusion Test Cell experiment. Lopez-Alegria is interviewed in Spanish by two Spanish radio show hosts. Earth views include cloud cover, the Earth's horizon and atmospheric boundary layers, and several oceans.

Characterizing the Turbulent Wind Flow Near a Wind Barrier Using a Data Set Collected with an Array of Sonic Anemometers

DTIC Science & Technology

2009-05-01

2009 Approved for public release; distribution unlimited. NOTICES...Approved for public release; distribution unlimited. ii REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704-0188 Public reporting burden...D’Arcy, Scott Elliott, Thomas Truong, and Michael Davalos 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) U.S. Army

Description of Streptococcus pneumoniae Infections in Burn Patients

DTIC Science & Technology

2010-01-01

Description of Streptococcus pneumoniae infections in burn patients§ Jessie S. Glasser a, Michael L. Landruma,b,c, Kevin K. Chung a,d, Duane R...Staphylococcus aureus. Although Streptococcus pneumoniae infections are common in the community and can cause nosocomial infections , the incidence and...risk factors for pneu- mococcal infections in burn patients is unclear. Methods: We performed an electronic retrospective chart review to collect rates

Development of Methods to Account for HCl and Cl2 from Open Burning and Characterization of Emissions from the Open Burning of Three Selected Propellants

DTIC Science & Technology

1996-09-01

Burning of Three Selected Propellants 6. AUTHOR(S) J.L Wilcox, B. Entezam, M.J. Molenaar , & T.R. Shreeve 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS...Physical Test Division West Desert Test Center Ben Entezam Michael J Molenaar Thomas Russell Shreeve Andrulis Research Corporation Contract No. DAAD09

A Risk-Based Approach for Aerothermal/TPS Analysis and Testing

DTIC Science & Technology

2007-07-01

RTO-EN-AVT-142 17 - 1 A Risk-Based Approach for Aerothermal/ TPS Analysis and Testing Michael J. Wright∗ and Jay H. Grinstead† NASA Ames...of the thermal protection system ( TPS ) is to protect the payload (crew, cargo, or science) from this entry heating environment. The performance of...the TPS is determined by the efficiency and reliability of this system, typically measured

Army Systems Engineering Career Development Model

DTIC Science & Technology

2014-01-30

Army Systems Engineering Career Development Model Interim Technical Report SERC -2014-TR-042-1 January 30, 2014 Principal Investigators Dr. Val...Gavito, Stevens Institute of Technology Dr. Michael Pennotti, Stevens Institute of Technology Task Order 004, RT 104 Report No. SERC -2014-TR-042-1...Institute of Technology 8. PERFORMING ORGANIZATION REPORT NUMBER SERC -2014-TR-042-1 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) DASD

Human Factors Research in Aircrew Performance and Training

DTIC Science & Technology

1989-08-01

and development called instructional design (Gagn6, Briggs , & Wager, 1988). Developments in computer-based instruction promise to increase training...Handbook of human factors (pp. 976-1011). New York: Wiley & Sons. Gagn6, R. M., Briggs , L. J., & Wager, W. W. (1988). Principles of instructional...SERVICE: SUPPORT TO MULTITRACK TESTING Dr. D. Michael McAnulty, Mr. Gary Coker, Ms. Cassandra Hocutt, Ms. Stephanie Noland, and Mr. Kenneth Persin

Question Generation via Overgenerating Transformations and Ranking

DTIC Science & Technology

2009-01-01

School of Computer Science Carnegie Mellon University 5000 Forbes Ave., Pittsburgh, PA 15213 www.lti.cs.cmu.edu c©2009, Michael Heilman and Noah A...PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Carnegie Mellon University ,School of Computer Science,5000 Forbes Ave,Pittsburgh,PA,15213 8...1967), in particular those that view a question as a transformation of a canonical declarative sentence ( Chomsky , 1973). In computational linguistics

Ensuring a Safe Technological Revolution

DTIC Science & Technology

2016-12-01

Defense AT&L: November-December 2016 14 Ensuring a Safe Technological Revolution William E. Frazier, Ph.D. n Elizabeth L. McMichael n Jennifer...for 5 years, working on nonferrous welding and AM and has an M.S. in Mechanical Engineering from the University of Maryland, Baltimore County. I n...has acceptable proper- ties. A “certified” part can perform properly in its operating environment . The conventional qualification/certification

Factors Modulating Estrogen Receptor Activity

DTIC Science & Technology

1997-07-01

public release; distribution unlimited The views, opinions and/or findings contained in this report are those of the author( s ) and should not be...TITLE AND SUBTITLE Activity Factors Modulating Estrogen Receptor 6. AUTHOR( S ) Michael J. Garabedian, Ph.D. 7. PERFORMING ORGANIZATION NAME( S ) AND...ADDRESS(ES) New York University Medical Center New York, New York 10016 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) Commander U.S

Thermal Management of Quantum Cascade Lasers in an individually Addressable Array Architecture

DTIC Science & Technology

2016-02-08

Thermal Management of Quantum Cascade Lasers in an Individually Addressable Monolithic Array Architecture Leo Missaggia, Christine Wang, Michael...power laser systems in the mid-to-long-infrared wavelength range. By virtue of their demonstrated watt-level performance and wavelength diversity...quantum cascade laser (QCL) and amplifier devices are an excellent choice of emitter for those applications. To realize the power levels of interest

Models of Success, Teacher Quality and Student Disciplinary Infraction: A Critical Analysis of Chicago's Urban Preparatory Academies and Harlem Children's Zone

ERIC Educational Resources Information Center

Williams, John A., III; Wiggan, Greg

2016-01-01

School discipline disparities in U.S. education is accompanied by a litany of literature that focuses on African Americans in low-performing urban schools (Civil Right Project, 2000; Losen, 2011; Mendez & Knoff, 2003; Skiba, Michael, Nardo & Peterson, 2002; Wilson, 2014). Public K-12 institutions in the U.S. report that African Americans…

Pulling the Parent Trigger--Forum. "Education Next" Talks with Ben Austin and Michael J. Petrilli

ERIC Educational Resources Information Center

Austin, Ben; Petrilli, Michael J.

2013-01-01

Championed by California-based Parent Revolution, and adopted first by California in early 2010, more than a half-dozen states now have parent trigger laws. The parent trigger, which allows a majority of parents at a low-performing school to vote to seize control from the local district, has been wielded at four California schools. Is the parent…

Active Learning with Statistical Models.

DTIC Science & Technology

1995-01-01

Active Learning with Statistical Models ASC-9217041, NSF CDA-9309300 6. AUTHOR(S) David A. Cohn, Zoubin Ghahramani, and Michael I. Jordan 7. PERFORMING...TERMS 15. NUMBER OF PAGES Al, MIT, Artificial Intelligence, active learning , queries, locally weighted 6 regression, LOESS, mixtures of gaussians...COMPUTATIONAL LEARNING DEPARTMENT OF BRAIN AND COGNITIVE SCIENCES A.I. Memo No. 1522 January 9. 1995 C.B.C.L. Paper No. 110 Active Learning with

Developing Molecular Genetic Tools to Facilitate Economic Production in Green Algae

DTIC Science & Technology

2012-09-10

Economic Production in Green Algae FA9550-10-1-0052 Georgianna, David, R Gimpel, Javier Hannon, Michael, J Mayfield, Stephen, P Prof. Stephen...Final Performance Report Project Title: Developing Molecular Genetic Tools to Facilitate Economic Production in Green Algae Award Number... ECONOMIC PRODUCTION IN GREEN ALGAE ABSTRACT It is now accepted that algae have enormous potential to generate economically viable and

After This Nothing Happened

ERIC Educational Resources Information Center

Alsop, Steve; Fawcett, Leesa

2010-01-01

In response to Michiel van Eijck and Wolff-Michael Roth's article and Michael Mueller and Deborah Tippin's rejoinder, we explore traditional ecological knowledges as science education. Adopting a stance of situated partial perspectives, and drawing on selected literature in science and technology studies and feminist postcolonial theories, we…

Theory and practice in action: the contributions of Michael Perkins to clinical linguistics.

PubMed

Damico, Jack S; Lynch, Karen E

2013-01-01

This article reviews the scholarly contributions of Michael R. Perkins in the discipline of clinical linguistics and provides some indication of the reasons that he has been so successful. Three primary attributes were described through an analysis of his publications.

Operational Art in Cyber Defense

DTIC Science & Technology

2013-04-16

a personal curiosity. I used the masculine when referring to the Commander and the adversary throughout this paper for brevity. Alanis 1...issue 63, (4th quarter 2011): 70-73. 13 Carl von Clausewitz, On War, ed. Michael Howard and Peter Paret, trans . Michael Howard and Peter Paret

Michael Faraday on the Learning of Science and Attitudes of Mind.

ERIC Educational Resources Information Center

Crawford, Elspeth

1998-01-01

Makes use of Michael Faraday's ideas on learning, focusing on his attitudes toward the unknowns of science and the development of an attitude that improves scientific decision making. This approach acknowledges that there is an inner struggle involved in facing unknowns. (DDR)

KENNEDY SPACE CENTER, FLA. -- From left, NASA Deputy Program Manager of the Space Shuttle Program Michael Wetmore, United Space Alliance (USA) Vice President and Space Shuttle Program Manager Howard DeCastro, NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik, and a USA technician examine cold plates in Orbiter Processing Facility Bay 2. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.

NASA Image and Video Library

2003-12-19

KENNEDY SPACE CENTER, FLA. -- From left, NASA Deputy Program Manager of the Space Shuttle Program Michael Wetmore, United Space Alliance (USA) Vice President and Space Shuttle Program Manager Howard DeCastro, NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik, and a USA technician examine cold plates in Orbiter Processing Facility Bay 2. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.

Invited Commentary: Continuing to Loosen the Constraints on Epidemiology in an Age of Change-A Comment on McMichael's "Prisoners of the Proximate".

PubMed

Galea, Sandro

2017-06-01

Published in 1999, McMichael's "Prisoners of the Proximate: Loosening the Constraints on Epidemiology in an Age of Change" (Am J Epidemiol. 1999;149(10):887-897) outlined an exciting vision for epidemiology as the field that that can help us better understand the drivers of population health so that we may intervene, paving the way for healthier populations. McMichael's paper remains today what it was when it was first published: clear, thoughtful, provocative, and usefully prescriptive in its call to action. McMichael identified 4 constraints facing epidemiology. The field has risen to this challenge and addressed some of these constraints. I discuss how successful (or not) we have been in addressing each of these 4 challenges. © The Author 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Thirty Points About Motivation From Skinner's Book Verbal Behavior

PubMed Central

Sundberg, Mark L.

2013-01-01

Skinner discussed the topic of motivation in every chapter of the book Verbal Behavior (1957), usually with his preferred terminology of “deprivation, satiation, and aversive stimulation.” In the current paper, direct quotations are used to systematically take the reader through 30 separate points made by Skinner in Verbal Behavior that collectively provide a comprehensive analysis of his position regarding the role of motivation in behavior analysis. In addition, various refinements and extensions of Skinner's analysis by Jack Michael and colleagues (Laraway, Snycerski, Michael, & Poling, 2003; Michael, 1982, 1988, 1993, 2000, 2004, 2007) are incorporated, along with suggestions for research and applications for several of the points. PMID:23814363

Diastereoselective auxiliary- and catalyst-controlled intramolecular aza-Michael reaction for the elaboration of enantioenriched 3-substituted isoindolinones. Application to the synthesis of a new pazinaclone analogue

PubMed Central

Sallio, Romain; Lebrun, Stéphane; Capet, Frédéric; Agbossou-Niedercorn, Francine

2018-01-01

A new asymmetric organocatalyzed intramolecular aza-Michael reaction by means of both a chiral auxiliary and a catalyst for stereocontrol is reported for the synthesis of optically active isoindolinones. A selected cinchoninium salt was used as phase-transfer catalyst in combination with a chiral nucleophile, a Michael acceptor and a base to provide 3-substituted isoindolinones in good yields and diastereomeric excesses. This methodology was applied to the asymmetric synthesis of a new pazinaclone analogue which is of interest in the field of benzodiazepine-receptor agonists. PMID:29623121

Michael Fisher at King's College London

NASA Astrophysics Data System (ADS)

Domb, Cyril

1991-09-01

Michael Fisher spent the first 16 years of his academic life in the Physics Department of King's College, London, starting as an undergraduate and ending as a full professor. A survey is undertaken of his activities and achievements during the various periods of this phase of his career.

Michael Fisher at King's College London

NASA Astrophysics Data System (ADS)

Domb, Cyril

Michael Fisher spent the first 16 years of his academic life in the Physics Department of King's College, London, starting as an undergraduate and ending as a full professor. A survey is undertaken of his activities and achievements during the various periods of this phase of his career.

Passings to note: Paul Michael Packman, MD; S. Charles Schulz, MD.

PubMed

Black, Donald W

2018-02-01

One of the keys to the success of Annals of Clinical Psychiatry has always been the tireless efforts of our dedicated Editorial Board. We recently lost 2 longtime Editorial Board members, Drs. Paul Michael Packman and S. Charles Schulz. Both will be greatly missed.

Reading Michael Apple--The Sociological Imagination at Work

ERIC Educational Resources Information Center

Ball, Stephen J.

2007-01-01

This article discusses Michael Apple's contribution to the sociology of education and education policy analysis and the politics of education. It focuses on ways of "reading" Apple as an intellectual and an activist and looks at the trajectory of his work over a long and illustrious career.

David Cozad, Michael Schumacher and/or Brad Peterson (d/b/a Credit Island Recycling), Davenport, Iowa

EPA Pesticide Factsheets

The EPA is providing notice of proposed Administrative Penalty Assessment against David Cozad, Michael Schumacher and/or Brad Peterson (d/b/a Credit Island Recycling), for alleged violations of an industrial stormwater permit issued by IDNR for an applianc

The Holocaust and Education: An Interview with Michael Berenbaum.

ERIC Educational Resources Information Center

Goldberg, Mark

1997-01-01

In January 1997, Michael Berenbaum became president and chief executive officer of Survivors of the Shoah Visual History Foundation, the organization established by filmmaker Steven Spielberg after completing "Schindler's List." Since 1994, the foundation has been recording eyewitness testimony on the Holocaust. Berenbaum's mandate is to…

Decisionmaker Forums

DTIC Science & Technology

2005-03-01

Committee professional staff, Brian Hurley of Edward Martin & Associates, Michael Kussman of the VA, Steve Lillie of DoD, Steve Mirick ofAMSUSBob...Michael Kussman of VHA; Bruce Levine of VHA; Miklos Losonczy of VHA; Susan Mather of VHA; Theodore Nam of DoD; Harold Wain of DoD; Terry Washam of

HEADSTONES OF BERNARD AND MICHAEL JODD, FATHERANDSON CIVILIANS RESPONSIBLE FOR ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

HEADSTONES OF BERNARD AND MICHAEL JODD, FATHER-AND-SON CIVILIANS RESPONSIBLE FOR CONSTRUCTION OF BRICK PERIMETER WALL WHO DIED OF YELLOW FEVER DURING WALL CONSTRUCTION. VIEW TO WEST. - Baton Rouge National Cemetery, 220 North 19th Street, Baton Rouge, East Baton Rouge Parish, LA

Michael Beitz: Objects of Communication

ERIC Educational Resources Information Center

Hoefferle, Mary

2014-01-01

For this Instructional Resource, the author interviewed contemporary sculptor Michael Beitz, who uses art to explore the role of designed objects in human communication and emotional experience. This column was written in response to calls for using Enduring Understandings/Big Ideas (National Coalition for Core Arts Standards, 2013; Stewart &…

File System Virtual Appliances: Portable File System Implementations

DTIC Science & Technology

2009-05-01

Mobile Computing Systems and Applications, Santa Cruz, CA, 1994. IEEE. [10] Michael Eisler , Peter Corbett, Michael Kazar, Daniel S. Nydick, and...Gingell, Joseph P. Moran, and William A. Shannon. Virtual Memory Architec- ture in SunOS. In USENIX Summer Conference, pages 81–94, Berkeley, CA, 1987

INCORPORATION OF MECHANISTIC INFORMATION IN THE ARSENIC PBPK MODEL DEVELOPMENT PROCESS

EPA Science Inventory

INCORPORATING MECHANISTIC INSIGHTS IN A PBPK MODEL FOR ARSENIC

Elaina M. Kenyon, Michael F. Hughes, Marina V. Evans, David J. Thomas, U.S. EPA; Miroslav Styblo, University of North Carolina; Michael Easterling, Analytical Sciences, Inc.

A physiologically based phar...

Introduction to Software Design

DTIC Science & Technology

1989-01-01

Schedules 20 major contributions. We also acknowledge the helpful Worked Examples 20 comments of Larry Peters, Michael Jackson . and Bob Glass. Exercises 20...contrasted with the related For a more general approach to the use of JSP, see work of Warnner and Michael Jackson (JSP). The [Cameron83]. [Ingovaldsson86

Michael Griffin Senate Hearing

NASA Image and Video Library

2005-05-17

NASA Administrator Dr. Michael Griffin is seen during his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

Michael Griffin Senate Hearing

NASA Image and Video Library

2005-05-17

NASA Administrator Dr. Michael Griffin smiles during his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

Michael Griffin Senate Hearing

NASA Image and Video Library

2005-05-17

NASA Administrator Dr. Michael Griffin delivers a statement during testimony in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

Virtually complete control of simple and face diastereoselectivity in the Michael addition reactions between achiral equivalents of a nucleophilic glycine and (S)- or (R)-3-(E-enoyl)-4-phenyl-1,3-oxazolidin-2-ones: practical method for preparation of beta-substituted pyroglutamic acids and prolines.

PubMed

Soloshonok, Vadim A; Ueki, Hisanori; Tiwari, Rohit; Cai, Chaozhong; Hruby, Victor J

2004-07-23

This study demonstrates a new strategy for controlling the stereochemical outcome of the Michael addition reactions between nucleophilic glycine equivalents and alpha,beta-unsaturated carboxylic acid derivatives: The addition reactions between achiral Ni(II)-complex of the Schiff base of glycine with o-[N-alpha-pycolylamino]acetophenone and (S)- or (R)-3-(E-enoyl)-4-phenyl-1,3-oxazolidin-2-ones were shown to occur at room temperature in the presence of nonchelating organic bases and, most notably, with very high stereoselectivity at both newly formed stereogenic centers. Thus, the chiral 4-phenyl-1,3-oxazolidin-2-one moiety was found to control efficiently both face diastereoselectivities of the glycine derived enolate and the C,C double bond of the Michael acceptor. The new strategy developed in this work is methodologically superior to previous methods, most notably in terms of generality and synthetic efficiency. Excellent chemical yields and diastereoselectivities, combined with the simplicity of the experimental procedures, render the present method of immediate use for preparing various 3-substituted pyroglutamic acids and related amino acids (glutamic acids, glutamines, prolines, etc.) available via conventional transformations of the former.

Weakness, Belonging, and the Intercordia Experience: The Logic and Limits of Dissonance as a Transformative Learning Tool

ERIC Educational Resources Information Center

Locklin, Reid B.

2010-01-01

Educational theorist Richard Kiely highlights the central importance of "high intensity dissonance" in successful international service-learning. This essay applies Kiely's model of dissonance and transformative learning to Intercordia, an international service-learning program offered at the University of St. Michael's College and the…

Residential Group Care Quarterly. Volume 7, Number 3, Winter 2007

ERIC Educational Resources Information Center

Shenk, Emily, Ed.

2007-01-01

"Residential Group Care Quarterly" is published four times a year by the Child Welfare League of America (CWLA). This issue contains the following articles: (1) Building a Lasting Agency: The Leadership Institute (Letitia Howland); (2) For Our Safety: Examining High-Risk Interventions for Children and Youth (Michael A. Nunno, Lloyd Bullard, and…

Space: The Final Frontier in the Learning of Science?

ERIC Educational Resources Information Center

Milne, Catherine

2014-01-01

In "Space", relations, and the learning of science", Wolff-Michael Roth and Pei-Ling Hsu use ethnomethodology to explore high school interns learning shopwork and shoptalk in a research lab that is located in a world class facility for water quality analysis. Using interaction analysis they identify how spaces, like a research…

Department of Defense Public Key Infrastructure Token Protection Profile. Version 2.0

DTIC Science & Technology

2001-03-12

Profile Authors: Tamara Cleveland, Booz·Allen & Hamilton Inc. Michael Alexander, Booz·Allen & Hamilton Inc. Asok Ganguly, Booz·Allen & Hamilton Inc...testing, and electron beam testing. • Other attacks, such as UV or X- rays or high temperatures, could cause erasure of memory. However, erasure of selected

Helping Children with Behavior Problems (Through In-School Suspension).

ERIC Educational Resources Information Center

Collins, Christopher G.

This article describes an in-class suspension program in a junior high school, designed by the Turn Around Program (TAP) committee of the Myron J. Michael School (Kingston, New York). The committee developed a specific model to fit their needs, emphasizing reform rather than punishment. Suspended students received tutoring, remediation, and…

High Court Hesitant to Bar Pledge in Schools

ERIC Educational Resources Information Center

Hendrie, Caroline

2004-01-01

This article reports on a lawsuit filed by Michael A. Newdow, a California atheist, on behalf of his daughter, against inclusion of the words "under God" in public schools' recitals of the United States Pledge of Allegiance. He said that the words "under God" represent "religious dogma" that is needlessly divisive.…

HIGHLY DIASTEREOSELECTIVE MICHAEL ADDITION OF FLAVANONE TO ITS CHALCONE PRECURSOR UNDER SOLVENT-FREE CONDITIONS USING MICROWAVES

EPA Science Inventory

Substituted 2'-hydroxychalcones were found to give an equilibrium mixture of the starting chalcone and the corresponding flavanone in 4:6 - 1:3 ratio in the presence of various supports and MW irradiation. MW irradiation of 2'-hydroxychalcones in the presence of DBU gave two hit...

A First Step Towards Network Security Virtualization: From Concept to Prototype

DTIC Science & Technology

2015-10-01

ec2 security groups. http://docs.aws.amazon.com/AWSEC2/latest/UserGuide/using-network- security.html. [3] Jeffrey R. Ballard, Ian Rae, and Aditya...20] Matthew L. Meola Michael J. Freedman Jennifer Rexford Nate Foster, Rob Harrison and David Walker. Frenetic: A High-Level Langauge for OpenFlow

Stereoselective syntheses of four diastereomers of 3,9,12-trihydroxycalamenene via a benzobicyclo[3.3.1] intermediate.

PubMed

Sun, Yongquan; Yu, Binxun; Wang, Xiaolei; Tang, Shibing; She, Xuegong; Pan, Xinfu

2010-06-18

The highly stereoselective syntheses of four diastereomers of natural 3,9,12-trihydroxycalamenene are described. The syntheses highlight the utility of an unusual framework of benzobicyclo[3.3.1] lactones, which were accomplished via an intramolecular Friedel-Crafts-type Michael addition of alpha,beta-unsaturated lactones.

"The Hunger Games" and Project-Based Learning

ERIC Educational Resources Information Center

Educational Horizons, 2013

2013-01-01

Mary Mobley teaches English and Michael Chambers teaches world history at Manor New Technology High School, a STEM school, in Manor, Texas. In this article, they talk about how they used "The Hunger Games" by Suzanne Collins to teach their students about forms of government between World War I and World War II, and "Edutopia"…

How We Know Collaboration Works

ERIC Educational Resources Information Center

Anrig, Greg

2015-01-01

For the 12 years that Michael Bloomberg was mayor of New York City, the Big Apple was home to the nation's largest experiment in implementing the business model of education reform. The numbers of public school closings and new charter schools soared, while the high school student assignment system was overhauled to be driven by choice. By the…

An exceptionally potent inducer of cytoprotective enzymes: elucidation of the structural features that determine inducer potency and reactivity with Keap1.

PubMed

Dinkova-Kostova, Albena T; Talalay, Paul; Sharkey, John; Zhang, Ying; Holtzclaw, W David; Wang, Xiu Jun; David, Emilie; Schiavoni, Katherine H; Finlayson, Stewart; Mierke, Dale F; Honda, Tadashi

2010-10-29

The Keap1/Nrf2/ARE pathway controls a network of cytoprotective genes that defend against the damaging effects of oxidative and electrophilic stress, and inflammation. Induction of this pathway is a highly effective strategy in combating the risk of cancer and chronic degenerative diseases, including atherosclerosis and neurodegeneration. An acetylenic tricyclic bis(cyano enone) bearing two highly electrophilic Michael acceptors is an extremely potent inducer in cells and in vivo. We demonstrate spectroscopically that both cyano enone functions of the tricyclic molecule react with cysteine residues of Keap1 and activate transcription of cytoprotective genes. Novel monocyclic cyano enones, representing fragments of rings A and C of the tricyclic compound, reveal that the contribution to inducer potency of the ring C Michael acceptor is much greater than that of ring A, and that potency is further enhanced by spatial proximity of an acetylenic function. Critically, the simultaneous presence of two cyano enone functions in rings A and C within a rigid three-ring system results in exceptionally high inducer potency. Detailed understanding of the structural elements that contribute to the reactivity with the protein sensor Keap1 and to high potency of induction is essential for the development of specific and selective lead compounds as clinically relevant chemoprotective agents.

The LENS Facilities and Experimental Studies to Evaluate the Modeling of Boundary Layer Transition, Shock/Boundary Layer Interaction, Real Gas, Radiation and Plasma Phenomena in Contemporary CFD Codes

DTIC Science & Technology

2010-04-01

Layer Interaction, Real Gas, Radiation and Plasma Phenomena in Contemporary CFD Codes Michael S. Holden, PhD CUBRC , Inc. 4455 Genesee Street Buffalo...NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) CUBRC , Inc. 4455 Genesee Street Buffalo, NY 14225, USA 8. PERFORMING...HyFly Navy EMRG Reentry-F Slide 2 X-43 HIFiRE-2 Figure 17: Transition in Hypervelocity Flows: CUBRC Focus – Fully Duplicated Ground Test

Outstanding conference paper award 2014 IEEE nuclear and space radiation effects conference

DOE PAGES

Dodds, Nathaniel Anson; Schwank, James R.; Shaneyfelt, Marty R.; ...

2014-12-01

The recipients of the 2014 NSREC Outstanding Conference Paper Award are Nathaniel A. Dodds, James R. Schwank, Marty R. Shaneyfelt, Paul E. Dodd, Barney L. Doyle, Michael Trinczek, Ewart W. Blackmore, Kenneth P. Rodbell, Michael S. Gordon, Robert A. Reed, Jonathan A. Pellish, Kenneth A. LaBel, Paul W. Marshall, Scot E. Swanson, Gyorgy Vizkelethy, Stuart Van Deusen, Frederick W. Sexton, and M. John Martinez, for their paper entitled "Hardness Assurance for Proton Direct Ionization-Induced SEEs Using a High-Energy Proton Beam." For older CMOS technologies, protons could only cause single-event effects (SEEs) through nuclear interactions. Numerous recent studies on 90 nmmore » and newer CMOS technologies have shown that protons can also cause SEEs through direct ionization. Furthermore, this paper develops and demonstrates an accurate and practical method for predicting the error rate caused by proton direct ionization (PDI).« less

Outstanding conference paper award 2014 IEEE nuclear and space radiation effects conference

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dodds, Nathaniel Anson; Schwank, James R.; Shaneyfelt, Marty R.

The recipients of the 2014 NSREC Outstanding Conference Paper Award are Nathaniel A. Dodds, James R. Schwank, Marty R. Shaneyfelt, Paul E. Dodd, Barney L. Doyle, Michael Trinczek, Ewart W. Blackmore, Kenneth P. Rodbell, Michael S. Gordon, Robert A. Reed, Jonathan A. Pellish, Kenneth A. LaBel, Paul W. Marshall, Scot E. Swanson, Gyorgy Vizkelethy, Stuart Van Deusen, Frederick W. Sexton, and M. John Martinez, for their paper entitled "Hardness Assurance for Proton Direct Ionization-Induced SEEs Using a High-Energy Proton Beam." For older CMOS technologies, protons could only cause single-event effects (SEEs) through nuclear interactions. Numerous recent studies on 90 nmmore » and newer CMOS technologies have shown that protons can also cause SEEs through direct ionization. Furthermore, this paper develops and demonstrates an accurate and practical method for predicting the error rate caused by proton direct ionization (PDI).« less

Really Large Scale Computer Graphic Projection Using Lasers and Laser Substitutes

NASA Astrophysics Data System (ADS)

Rother, Paul

1989-07-01

This paper reflects on past laser projects to display vector scanned computer graphic images onto very large and irregular surfaces. Since the availability of microprocessors and high powered visible lasers, very large scale computer graphics projection have become a reality. Due to the independence from a focusing lens, lasers easily project onto distant and irregular surfaces and have been used for amusement parks, theatrical performances, concert performances, industrial trade shows and dance clubs. Lasers have been used to project onto mountains, buildings, 360° globes, clouds of smoke and water. These methods have proven successful in installations at: Epcot Theme Park in Florida; Stone Mountain Park in Georgia; 1984 Olympics in Los Angeles; hundreds of Corporate trade shows and thousands of musical performances. Using new ColorRayTM technology, the use of costly and fragile lasers is no longer necessary. Utilizing fiber optic technology, the functionality of lasers can be duplicated for new and exciting projection possibilities. The use of ColorRayTM technology has enjoyed worldwide recognition in conjunction with Pink Floyd and George Michaels' world wide tours.

The Age of Irregular Warfare: So What?

DTIC Science & Technology

2010-01-01

Lynne Rienner, 2002), and Michael Vlahos , Fighting Identity: Sacred War and World Change (Westport, CT: Praeger Security Interna- tional, 2009). 7...the forms that warfare will take.” 8 I agree with Michael Vlahos that we poten- tially make matters worse by using the image of a triangle to depict

Michael E. Barnes: Award for Distinguished Professional Contributions to Institutional Practice

ERIC Educational Resources Information Center

American Psychologist, 2012

2012-01-01

Presents a short biography on the winner of the American Psychological Association's Award for Distinguished Professional Contributions to Institutional Practice. The 2012 winner is Michael E. Barnes for his pioneering leadership, dedication, and distinguished contributions to juvenile justice. As chief psychologist of the Superior Court of the…

Catalyst-free and solvent-free Michael addition of 1,3-dicarbonyl compounds to nitroalkenes by a grinding method

PubMed Central

Xie, Zong-Bo; Wu, Ming-Yu; He, Ting; Le, Zhang-Gao

2012-01-01

Summary An environmentally benign, fast and convenient protocol has been developed for the Michael addition of 1,3-dicarbonyl compounds to β-nitroalkenes in good to excellent yields by a grinding method under catalyst- and solvent-free conditions. PMID:22563352

Solving the Housing Equation: Michael P. Johnson

ERIC Educational Resources Information Center

Roach, Ronald

2005-01-01

Dr. Michael P. Johnson, an associate professor of management science and urban affairs at the H. John Heinz III School of Public Policy and Management at Carnegie Mellon University in Pittsburgh, is taking management science tools and innovative information technology applications to the housing field. Concerned that organizations that develop and…

Humanism in Education

ERIC Educational Resources Information Center

Armstrong, Michael

2015-01-01

This is the text of Michael Armstrong's address to the Brian Simon Centenary conference, held at the Institute of Education on 26 March 2015. Michael Armstrong celebrates the humanism that underlay Brian's belief in a common system of education, democratic and non-selective, and finds its counterpart in the creative practice of school children.

Michael Slote and "Sentimentalist Moral Education"

ERIC Educational Resources Information Center

Wren, Thomas

2010-01-01

Although I think most of what Michael Slote asserts in his article "Sentimentalist moral education" is correct, I worry about three important ideas that are conspicuous by their absence. The first is the possibility that human emotions and feelings are inherently cognitive, which is never considered in his psychological account of empathy. The…

Legitimacy and Penetration in Stability Operations; Setting the Conditions for Perpetual Failure

DTIC Science & Technology

2011-12-02

District or Provincial level. Taking the lessons from Vietnam and 124 Michael Crawshaw , Running a Country: The British Colonial Experience and its Relevance...Metrics of the Afghan War. CSIS presentation, Washington DC: Center for Strategic and International Studies, 2010. Crawshaw , Michael. Running a Country

New Models at Lasell: Q&A with President Michael Alexander

ERIC Educational Resources Information Center

Harney, John O.

2018-01-01

The "New England Journal of Higher Education" ("NEJHE") Executive Editor John O. Harney had the chance to catch up with Lasell College President Michael Alexander about the small Newton, Massachusetts, college's plans to challenge the higher education business model. The interview is presented in this article.

Goodbye Michael Gove

ERIC Educational Resources Information Center

Bassey, Michael

2014-01-01

Michael Gove was Secretary of State for Education from May 2010 to July 2014 when the Prime Minister sacked him. With strong opinions arising from his own life experiences and outstanding energy for reform, but severely limited understanding of education and a refusal to consult teachers and other professionals, he imposed half-baked ideas on the…

Michael Polanyi on the Education and Knowledge of Scientists.

ERIC Educational Resources Information Center

Jacobs, Struan

2000-01-01

Explains why teachers addressing the nature of science should know the work of Michael Polanyi. Outlines Polanyi's intellectual career and examines his ideas on the education of scientists, research, and knowledge. Polanyi presaged Kuhn, Feyerabend, and the constructivists, yet insisted that science produces true knowledge about reality. (Contains…

76 FR 21406 - Michael J. Aruta, M.D.; Decision and Order

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-15

... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 10-40] Michael J. Aruta, M.D.; Decision and Order ACTION: Correction. On Thursday, April 7, 2011, the Drug Enforcement Administration published the above-titled Decision and Order, as well as the Decision of the Administrative Law Judge (76...

Encyclopedia of Life

Science.gov Websites

Movement who took this action. Green Movement added text to "Guacharaca caribeña " on " action. Maggie Whitson added "Chorizema" to the collection "Cool Flowers". about 3 hours ago Reply Profile picture of C. Michael Hogan who took this action. C. Michael Hogan marked the

Michael Griffin Oath Of Office

NASA Image and Video Library

2005-04-14

John H. Marburger, Science Adviser to the President and Director of the Office of Science and Technology Policy (OSTP), left, talks with NASA Administrator Michael Griffin, center, while his wife Rebecca and daughter Katie look on following his swearing-in, Thursday, April 14, 2005, in Washington. Photo Credit: (NASA/Renee Bouchard)

File System Virtual Appliances: Portable File System Implementations

DTIC Science & Technology

2010-04-01

com- puting. Santa Cruz, CA, 1994. [12] Michael Eisler , Peter Corbett, Michael Kazar, Daniel S. Nydick, and Christopher Wagner. Data ontap gx: a...fuse.sourceforge.net. [15] R. A. Gingell, J. P. Moran, and W. A. Shannon. Virtual memory architecture in sunos. USENIX ATC, pages 81–94, 1987 . [16

78 FR 25273 - Determination and Declaration Regarding Emergency Use of in Vitro Diagnostics for Detection of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-30

... Respiratory Protection Devices, and Respiratory Support Devices signed by then Secretary Michael Leavitt on... Act Declaration for Pandemic Influenza Diagnostics, Personal Respiratory Protection Devices, and Respiratory Support Devices signed by then Secretary Michael Leavitt on December 17, 2008. Notice of the EUAs...

The NATO Special Operations Forces Transformation Initiative: Opportunities and Challenges

DTIC Science & Technology

2009-03-01

reality in the starkest possible terms when British Lieutenant General Sir Michael Jackson refused to comply with the orders of the then-SACEUR...http://www.strategicstudiesinstitute.army.mil/pdffiles/PUB889.pdf (accessed 15 November 2008). 58 General Sir Michael Jackson , “My Clash With NATO

Human-Computer System Development Methodology for the Dialogue Management System.

DTIC Science & Technology

1982-05-01

methodologies [HOSIJ78] are given below: I. The Michael Jackson Methodology [JACKM75] 2. The Warnier-Orr Methodolgy [HOSIJ78] 3. SADT (Structured...All the mentioned methodologies use top-down development strategy. The first two methodologies above ( Michael Jackson and Warnier-Orr) use data as the

The Use of Portfolios in Leadership Education

ERIC Educational Resources Information Center

Olsen, Paul E.

2009-01-01

This paper discusses the benefits of using student portfolios in undergraduate leadership education at Saint Michael's College. There appears to be a natural link between the use of portfolios as a tool to facilitate and document leadership growth and development. The Business Administration and Accounting Department at Saint Michael's College…

Michael Griffin Senate Hearing

NASA Image and Video Library

2005-05-17

Senator Trent Lott, R-Miss., questions NASA Administrator Dr. Michael Griffin during his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

Michael Griffin Senate Hearing

NASA Image and Video Library

2005-05-17

NASA Administrator Dr. Michael Griffin is seen prior to his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

Q & A with Ed Tech Leaders: Interview with J. Michael Spector

ERIC Educational Resources Information Center

Shaughnessy, Michael F.; Fulgham, Susan M.

2015-01-01

J. Michael Spector's academic preparation was in philosophy--epistemology and logic, primarily. His dissertation was on skepticism in modern philosophy, and that led him to a deep-seated appreciation for classical skepticism. The word "skeptic" is derived from the Greek word "skepsis," which means investigation. While the…

Comments on Michael (1993): Establishing Operations

ERIC Educational Resources Information Center

Moore, J.

2013-01-01

The present comments concern Michael's concept of motivative variables, and the implications of that concept for our understanding of the nature of reinforcement as well as the extinction of responses maintained through positive and negative reinforcement. We note that both extinction and altering motivative variables decrease responding, but…

Michael Faraday's Bicentenary.

ERIC Educational Resources Information Center

Williams, L. Pearce; And Others

1991-01-01

Six articles discuss the work of Michael Faraday, a chemist whose work revolutionized physics and led directly to both classical field and relativity theory. The scientist as a young man, the electromagnetic experiments of Faraday, his search for the gravelectric effect, his work on optical glass, his laboratory notebooks, and his creative use of…

Early Prediction of Lupus Nephritis Using Advanced Proteomics

DTIC Science & Technology

2010-06-01

SELDI-TOF-MS. Additional proteomic profiling studies using NMR- and MS-based metabonomics have been completed, and LC/MS based protein profiling using...Flight mass spectrometry (SELDI-TOF-MS). Changes in proteomic profiles will be confirmed and enhanced using NMR- and MS-based metabonomics , by Dr...performed using NMR- and MS-based metabonomics at Miami University, in the laboratory of Dr. Michael Kennedy. Initial spectra and profiles obtained show

Macrocognition in Complex Team Problem Solving

DTIC Science & Technology

2007-06-01

Organization: Office of Naval Research Complete Address: Dr Michael Letsky Office of Naval Research Life Sciences Department Code 341 Rm 1051 875...S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Office of Naval Research ,Code 341 Rm...distribution unlimited 13. SUPPLEMENTARY NOTES Twelfth International Command and Control Research and Technology Symposium (12th ICCRTS), 19-21 June

CDRA Valve RR

NASA Image and Video Library

2013-10-28

ISS037-E-021985 (28 Oct. 2013) --- In the International Space Station?s Tranquility node, NASA astronaut Michael Hopkins (right) and European Space Agency astronaut Luca Parmitano, both Expedition 37 flight engineers, perform routine in-flight maintenance within the Carbon Dioxide Removal Assembly. This device removes carbon dioxide from the station?s atmosphere and is part of the station?s Environmental Control and Life Support System that provides clean water and air to the crew.

Barratt with MSG in Kibo

NASA Image and Video Library

2009-04-29

ISS019-E-012391 (29 April 2009) --- Astronaut Michael Barratt, Expedition 19/20 flight engineer, activates the Microgravity Science Glovebox (MSG) from its A31p laptop, initiates and conducts a session, the first of Increment 19, with the experiment Smoke Point In Co-flow Experiment (SPICE), performed in the MSG and controlled by its A31p with SPICE micro-drives in the Kibo laboratory of the International Space Station.

Rich Representations with Exposed Semantics for Deep Visual Reasoning

DTIC Science & Technology

2016-06-01

Gupta, Abh inav; Hebert, Martial ; Aminoff, Elissa; Park, HyunSoo; Forsyth, David; Shi, Jianbo; Tarr, Michael Se. TASK NUMBER Sf. WORK UNIT NUMBER 7...approach performs equally well or better when compared to the state-of-the- art . We also expanded our research on perceiving the interactions between...cross-instance correspondences. We demonstrated that our end-to-end trained ConvNet supervised by cycle-consistency outperforms state-of-the- art

KSC-97pc355

NASA Image and Video Library

1997-02-21

Accompanied by former astronaut Michael J. McCulley, several members of the STS-82 crew look at thermal protection system tile under the Space Shuttle Discovery on the runway at the Shuttle Landing Facility shortly after the conclusion of a 10-day mission to service the orbiting Hubble Space Telescope (HST). From left to right, they are Mission Specialist Steven A. Hawley; Michael J. McCulley, currently vice president and associate program manager for ground operations for the United Space Alliance at KSC; Mission Specialists Joseph R. "Joe" Tanner and Steven L. Smith (back to camera); and Payload Commander Mark C. Lee. STS-82 is the ninth Shuttle nighttime landing, and the fourth nighttime landing at KSC. The seven-member crew performed a record-tying five back-to-back extravehicular activities (EVAs) or spacewalks to service the telescope, which has been in orbit for nearly seven years. Two new scientific instruments were installed, replacing two outdated instruments. Five spacewalks also were performed on the first servicing mission, STS-61, in December 1993. Only four spacewalks were scheduled for STS-82, but a fifth one was added during the flight to install several thermal blankets over some aging insulation covering three HST compartments containing key data processing, electronics and scientific instrument telemetry packages. STS-82 was the 82nd Space Shuttle flight and the second mission of 1997

Novel Diffusion-Weighted MRI for High-Grade Prostate Cancer Detection

DTIC Science & Technology

2017-10-01

AWARD NUMBER: W81XWH-15-1-0346 TITLE: Novel Diffusion-Weighted MRI for High -Grade Prostate Cancer Detection PRINCIPAL INVESTIGATOR: Michael Abern...Unlimited The views, opinions and/or findings contained in this report are those of the author(s) and should not be construed as an official Department of...Diffusion-Weighted MRI for High -Grade Prostate Cancer Detection 5a. CONTRACT NUMBER 5b. GRANT NUMBER W81XWH-15-1-0346 5c. PROGRAM ELEMENT NUMBER 6

Hot film wall shear instrumentation for compressible boundary layer transition research

NASA Technical Reports Server (NTRS)

Schneider, Steven P.

1992-01-01

Experimental and analytical studies of hot film wall shear instrumentation were performed. A new hot film anemometer was developed and tested. The anemometer performance was not quite as good as that of commercial anemometers, but the cost was much less and testing flexibility was improved. The main focus of the project was a parametric study of the effect of sensor size and substrate material on the performance of hot film surface sensors. Both electronic and shock-induced flow experiments were performed to determine the sensitivity and frequency response of the sensors. The results are presented in Michael Moen's M.S. thesis, which is appended. A condensed form of the results was also submitted for publication.

Water-Cooled Data Center Packs More Power Per Rack | Poster

Cancer.gov

By Frank Blanchard and Ken Michaels, Staff Writers Behind each tall, black computer rack in the data center at the Advanced Technology Research Facility (ATRF) is something both strangely familiar and oddly out of place: It looks like a radiator. The back door of each cabinet is gridded with the coils of the Liebert cooling system, which circulates chilled water to remove heat generated by the high-speed, high-capacity, fault-tolerant equipment.

Technology Research, Integration, and Demonstration (TRIAD) Program, Delivery Order 0013: High Strain Rate Tension Testing of Titanium 6-2-4-2S at Temperature

DTIC Science & Technology

2016-06-01

ASSIGNED DISTRIBUTION STATEMENT. *//Signature// //Signature// BRIAN T. GOCKEL MICHAEL S. BROWN, Chief Program Manager Hypersonic Sciences Branch...Washington Headquarters Services, Directorate for Information Operations and Reports (0704-0188), 1215 Jefferson Davis Highway, Suite 1204, Arlington...STATEMENT A: Approved for public release. Distribution is unlimited. Figure 3. Room-Temperature High-Speed DIC Tensile Setup A slack adapter was

Making Constructive Simulations Relevant for Today’s Fight

DTIC Science & Technology

2010-03-08

Afghanistan. Dr. Michael Vlahos , a member of the National Security Assessment team of the National Security Analysis Department (NSAD) at the Johns Hopkins...www.carlisle.army.mil/DIME/documents/Szepesy%5B1%5D.pdf (accessed February 23, 2010). 20 13 Michael Vlahos , Culture’s Mask: War & Change after Iraq (Laurel

Admiral Raymond A. Spruance: Lessons in Adaptation from the Pacific

DTIC Science & Technology

2010-04-30

Association of the Class of 1907, 342. 54 Hough, 237. 55 Vlahos , Michael. The Blue Sword: The Naval War College and the American Mission, 1919-1941...Warfare: Theory and Practice. Newport, RI: U.S. Naval War College, 2009. Vlahos , Michael. The Blue Sword: The Naval War College and the American

The Politics of Education Revisited: Anthony Crosland and Michael Gove in Historical Perspective

ERIC Educational Resources Information Center

Finn, Mike

2015-01-01

This article traces continuity and change in the governance of British education through the comparison of two ministers, Anthony Crosland and Michael Gove. Taking Maurice Kogan's seminal "The Politics of Education" as the point of departure, the article highlights the role of political ideology in large-scale educational change, taking…

From Gouldner to Gramsci: The Making of Michael Apple's "Ideology and Curriculum"

ERIC Educational Resources Information Center

Gottesman, Isaac

2012-01-01

Michael Apple's "Ideology and Curriculum", published in 1979, helped initiate a broad turn in the field of education in the United States to Marxist thought as a lens through which to analyze the relationship between school and society. This classic text continues to inform scholarship in the field. While "Ideology" has…

A Good Time: A Conversation with C. Michael Nelson

ERIC Educational Resources Information Center

Zabel, Robert; Kaff, Marilyn; Teagarden, Jim

2015-01-01

C. Michael Nelson began his special education career as a teacher of adolescents with learning and behavior disorders. He has worked as a child psychologist and as a professor with the Department of Special Education and Rehabilitation Counseling at the University of Kentucky. He coordinated the graduate Personnel Preparation Program for Teachers…

Michael Duane after Risinghill: Rise and Fall of an Educational Celebrity

ERIC Educational Resources Information Center

Limond, David

2005-01-01

In this article an attempt is made to examine the continuing implications of the operation and closure of London's Risinghill school, a co-educational comprehensive extant from 1960 to 1965. It is suggested that Risinghill's controversial headteacher, Michael Duane (1915-1997), was an educational celebrity and folk hero amongst teachers and in…

Aza-Michael Reaction for an Undergraduate Organic Chemistry Laboratory

ERIC Educational Resources Information Center

Nigam, Manisha; Rush, Brittney; Patel, Jay; Castillo, Raul; Dhar, Preeti

2016-01-01

A green, aza-Michael reaction is described that can be used to teach undergraduate students conjugate addition of nitrogen nucleophile to an a,ß-unsaturated ester. Students analyze spectral data of the product obtained from the assigned reaction to determine product structure and propose the mechanism of its formation. The experiment requires…

Training and Mastery of Techniques in Wittgenstein's Later Philosophy: A Response to Michael Luntley

ERIC Educational Resources Information Center

Stickney, Jeff

2008-01-01

Responding to Michael Luntley's article, "Learning, Empowerment and Judgement," the author shows he cannot successfully make the following three moves: (1) dissolve the analytic distinction between learning by training and learning by reasoning, while advocating the latter; (2) diminish the role of training in Wittgenstein's philosophy, nor…

Gender Relations and Sexual Harassment in the Workplace: Michael Crichton's "Disclosure" as a Teaching Tool.

ERIC Educational Resources Information Center

Comer, Debra R.; Cooper, Elizabeth A.

1998-01-01

Describes how to use Michael Crichton's novel "Disclosure" and the film based on it for class discussions of such issues as what constitutes sexual harassment, harassment of men, relationship between sexual harassment and power, organizational responses to harassment, and gender differences in career advancement tactics. (SK)

Double hetero-Michael addition of N-substituted hydroxylamines to quinone monoketals: synthesis of bridged isoxazolidines.

PubMed

Yin, Zhiwei; Zhang, Jinzhu; Wu, Jing; Liu, Che; Sioson, Kate; Devany, Matthew; Hu, Chunhua; Zheng, Shengping

2013-07-19

A general synthesis of bridged isoxazolidines from a double hetero-Michael addition of N-substituted hydroxylamines to quinone monoketals has been developed. The different addition order of N-benzylhydroxylamine and N-Boc hydroxylamine is also discussed. Moreover, the various functionalities in the isoxazolidine products allow facile derivatization.

A Bibliographic Tribute to Jack Michael

ERIC Educational Resources Information Center

Esch, Barbara E.; Esch, John W.

2016-01-01

"In the late 1950's, Jack Michael, a bright but irritating young psychology instructor, moved from the Universities of Kansas to Houston to Arizona State. Along the way he befriended two nontraditional students, protected them through their Ph.D. programs, and turned them loose on the world: Teodoro Ayllon…and Montrose Wolf…" (Risley,…

Educational Implications of Michael Fishbane's "Sacred Attunement: A Jewish Theology"

ERIC Educational Resources Information Center

Marom, Daniel

2008-01-01

This article posits Michael Fishbane's Judaic scholarship as a prime resource for Jewish education. The link between the two fields can be made through a translation of the theological underpinnings of Fishbane's insights into Judaism to educational purposes and practices. Initial work with Jewish educators on establishing this link encouraged…

Broadening the Debate: Comments on Michael J. Feuer's "Moderating the Debate"

ERIC Educational Resources Information Center

Robertson, Emily

2009-01-01

In "Moderating the Debate: Rationality and the Promise of American Education", Michael Feuer argues that insights from cognitive science and the theory of bounded rationality can help us understand why educational policy makers overreach in seeking optimal solutions to educational problems. In this essay, Emily Robertson argues that cognitive…

The Power of the Powerless

ERIC Educational Resources Information Center

Welch, Cay

2009-01-01

This is a Pittsburgh story. It is about a boy named Michael Charles Metil--a boy that transformed many lives, including the author's. While visiting grandparents over the Christmas holiday in Latrobe, Pennsylvania in 1993, Michael became sick. He was lethargic, vomiting, and had some diarrhea. Little did his parents realize how very sick he was,…

Reframing Michael Scott: Exploring Inappropriate Workplace Communication

ERIC Educational Resources Information Center

Schaefer, Zachary A.

2010-01-01

Individuals who work in professional settings interact with others who may exhibit a variety of cultural beliefs and decision-making approaches. Page (2007) argues that cognitive diversity (i.e., how people approach and attempt to solve problems) is a vital asset in effective organizations. Michael Scott, who portrays the inept main character on…

Balancing Act: The U. S. Military’s Reliance on Contractors to Fulfill Operational-Level Logistical Requirements

DTIC Science & Technology

2014-05-15

Military Sealift Command. Combat Logistics Force (PM1), 1. 40 Ibid. 41 Michael Marquez, Richard Rayos, and John Mercado . Standard Port-Visit Forecasting...Series no. 8 (2012). Marquez, Michael, John Mercado , and Richard Rayos. Standard Port-Visit Forecasting Model for U.S. Navy Husbanding

Michael Hand, Indoctrination and the Inculcation of Belief

ERIC Educational Resources Information Center

Tan, Charlene

2004-01-01

In 'Religious Upbringing Reconsidered,' Michael Hand revisits the debate on the right of parents to give their children a religious upbringing in a liberal context. According to him, the logical difficulty lies in the fact that parents cannot both impart religious beliefs and avoid indoctrination. While Peter Gardner and Jim Mackenzie have…

The Educational Philosophies of Mordecai Kaplan and Michael Rosenak: Surprising Similarities and Illuminating Differences

ERIC Educational Resources Information Center

Schein, Jeffrey; Caplan, Eric

2014-01-01

The thoughts of Mordecai Kaplan and Michael Rosenak present surprising commonalities as well as illuminating differences. Similarities include the perception that Judaism and Jewish education are in crisis, the belief that Jewish peoplehood must include commitment to meaningful content, the need for teachers to teach from a position of…

Courtside: Gifted Irony?

ERIC Educational Resources Information Center

Zirkel, Perry A.

2005-01-01

During the 2002-03 school year, Michael B., Rebecca D., and Aldo V. were eighth-graders at the Regional Gifted Center program at the Beaubien School in the Chicago school system. In February, the Beaubien School held an annual contest for eighth-graders to determine the design for the class T-shirt. Michael was disappointed that his design did not…

C. P. Snow's "The Two Cultures": Michael Polanyi's Response and Context

ERIC Educational Resources Information Center

Jacobs, Struan

2011-01-01

C. P. Snow's "The Two Cultures" controversially contrasted science and literature, suggesting that neither scientists nor literary intellectuals have much in common with, and seldom bother speaking to, the other. Responding to Snow, Michael Polanyi argued that specialization has made modern culture, not twofold but manifold. In his major work,…

Against Dogma: A Reply to Michael Swan.

ERIC Educational Resources Information Center

Widdowson, H. G.

1985-01-01

Replies to two articles by Michael Swan entitled "A Critical Look at the Communicative Approach." Argues that Swan presents a distorted version of the communicative approach so as to present his own ideas more effectively and that he fails to offer evidence for his position on the practice of English language teaching. (SED)

The U.S.-Japan Alliance: Review of the Guidelines for Defense Cooperation

DTIC Science & Technology

2015-03-01

Cooperation: Process and Historical Impact, Michael J. Green and Koji Murata concluded that the guidelines failed to establish a clear understanding...Japan-U.S. Security Consultative Committee, November 27, 1978, available at <http://fas.org/news/japan/sisin1e.htm>. 4 Michael J. Green and Koji Murata

Polymer solutions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Krawczyk, Gerhard Erich; Miller, Kevin Michael

2011-07-26

There is provided a method of making a polymer solution comprising polymerizing one or more monomer in a solvent, wherein said monomer comprises one or more ethylenically unsaturated monomer that is a multi-functional Michael donor, and wherein said solvent comprises 40% or more by weight, based on the weight of said solvent, one or more multi-functional Michael donor.

78 FR 19149 - Small Generator Interconnection Agreements and Procedures; Supplemental Notice of Workshop

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-29

..., National Grid (Edison Electric Institute) [rtarr8] Michael Sheehan, P.E., Keyes, Fox & Wiedman L.L.P... Association of Regulatory Utility Commissioners [rtarr8] Sky Stanfield, Attorney, Keyes, Fox & Wiedman L.L.P... Policy, National Grid (Edison Electric Institute) [rtarr8] Michael Sheehan, P.E., Keyes, Fox & Wiedman L...

On the Distinction between Positive and Negative Reinforcement

ERIC Educational Resources Information Center

Iwata, Brian A.

2006-01-01

In this article, the author presents his views on Michael's (1975) and Baron and Galizio's (2005) arguments on eliminating the distinction between positive and negative reinforcement. He first discusses Michael's concept of these two types of operations and contrasts it with the notions of Baron and Galizio. The author provides the readers his own…

Dialogue on Modernity and Modern Education in Dispute

ERIC Educational Resources Information Center

Baker, Michael; Peters, Michael A.

2012-01-01

This is a dialogue or conversation between Michael Baker (MB) and Michael A. Peters (MP) on the concept of modernity and its significance for educational theory. The dialogue took place originally as a conversation about a symposium on modernity held at the American Educational Studies Association meeting 2010. It was later developed for…

Michael Driver: A Career Life to Remember

ERIC Educational Resources Information Center

Sundby, Dianne; Derr, C. Brooklyn

2007-01-01

Purpose: The purpose of this paper is to present a retrospective of the career life of Michael Driver, from the time of his Princeton graduate studies and early faculty years at Purdue University through the over three decades he spent at USC. Design/methodology/approach: The history and development of his theoretical and research interests are…

N-heterocyclic carbene-catalyzed tandem aza-benzoin/Michael reactions: on site reversal of the reactivity of N-Boc imines.

PubMed

Wu, Ke-Jia; Li, Gong-Qiang; Li, Yi; Dai, Li-Xin; You, Shu-Li

2011-01-07

A tandem NHC-catalyzed aza-benzoin/Michael reaction has been developed as a method to efficiently produce dihydroindenones and pyrrolidinone-containing tricycles. The novel reaction pattern involves tert-butyl aryl(tosyl)methylcarbamates reacting as both electrophile and nucleophile on the same carbon.

A Stability Police Force for the United States: Justification and Options for Creating U.S. Capabilities

DTIC Science & Technology

2009-01-01

Investigative Analysis, Ottawa: Royal Canadian Mounted Police, 2007; John E. Eck , Spencer Chainey, James G. Cameron , Michael Leitner, and Ronald E. Wilson...Kuwait,” Parameters, Vol. 21, No. 4, Winter 1991–1992. Eck , John E., Spencer Chainey, James G. Cameron , Michael Leitner, and Ronald E. Wilson

Tweeting Prayers and Communicating Grief over Michael Jackson Online

ERIC Educational Resources Information Center

Sanderson, Jimmy; Cheong, Pauline Hope

2010-01-01

Death and bereavement are human experiences that new media helps facilitate alongside creating new social grief practices that occur online. This study investigated how people's postings and tweets facilitated the communication of grief after pop music icon Michael Jackson died. Drawing on past grief research, religion, and new media studies, a…

European Adaptation to Expeditionary Warfare: Implications for the U.S. Army

DTIC Science & Technology

2002-11-01

than any other recent operation, highlighted Europe’s inability to deploy ground forces rapidly. General Sir Michael Jackson was only able to deploy...Security, Vol. 9, No. 4, Winter 2000, pp. 31-44. 48. Lieutenant-General Sir Michael Jackson , “KFOR: The Inside Story,” The RUSI Journal, Vol. 145, No

Q&A: Michael Honey

ERIC Educational Resources Information Center

Helicher, Karl

2007-01-01

The mid-1960s saw civil rights victories in Congress during Lyndon B. Johnson's presidency. In "Going Down Jericho Road," Michael Honey wrote how Martin Luther King Jr.'s final focus showed that the struggle for black and working class parity continued. The 1968 Memphis sanitation workers strike was a gritty struggle won in the streets by a host…

Michael Griffin Senate Confirmation Hearing

NASA Image and Video Library

2005-04-12

Dr. Michael Griffin testifies, Tuesday, April 12, 2005, during his confirmation hearing before the U.S. Senate Commerce Committee at the Russell Senate Office Building in Washington. If confirmed, Griffin, who currently heads the space department at the Johns Hopkins University Applied Physics Laboratory will become NASA's 11th administrator. Photo Credit (NASA/Renee Bouchard)

Michael Griffin Senate Confirmation Hearing

NASA Image and Video Library

2005-04-11

Dr. Michael Griffin testifies, Tuesday, April 12, 2005, during his confirmation hearing before the U.S. Senate Commerce Committee at the Russell Senate Office Building in Washington. If confirmed, Griffin, who currently heads the space department at the Johns Hopkins University Applied Physics Laboratory will become NASA's 11th administrator. Photo Credit (NASA/Renee Bouchard)

Michael Griffin Senate Hearing

NASA Image and Video Library

2005-05-17

U.S. Senator Bill Nelson. R-Fla., questions NASA Administrator Dr. Michael Griffin during his appearance in front of the Senate Commerce Committee Science and Space Subcommittee hearing on Human Space Flight: The Space Shuttle and Beyond, Wednesday, May 18, 2005, in the Russell Senate Office Building on Capitol Hill in Washington. Photo Credit: (NASA/Bill Ingalls)

Attending to hidden realities: contributions from the work of Michael Polanyi to supervision in pastoral care and counseling.

PubMed

Rodgerson, Thomas E

2008-01-01

In this article, the author suggests that concepts from the work of Michael Polanyi--such as the tacit dimension, subsidiary awareness, and commitment to a yet unrevealed, hidden reality--provide a theoretical basis for understanding the unique formation involved in pastoral care and counseling supervision.

A celebration of mechanics: from nano to macro. The J. Michael T. Thompson Festschrift issue.

PubMed

Elishakoff, Isaac

2013-06-28

This Theme Issue is dedicated to the topic 'Mechanics: from nano to macro' and marks the 75th birthday of Dr J. Michael T. Thompson, Fellow of the Royal Society, whose current affiliations are as follows: (i) Honorary Fellow, Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge; (ii) Emeritus Professor of Nonlinear Dynamics, Department of Civil, Environmental and Geomatic Engineering, University College London; and (iii) Professor of Theoretical and Applied Dynamics (Distinguished Sixth Century Chair, part-time), University of Aberdeen. He also serves as Chairman of the Board of Directors at ES-Consult (consulting engineers) in Copenhagen, Denmark. The pertinent question that arises from the very start is: should we first salute Michael and then describe the Theme Issue, or vice versa? Indeed, according to Blaise Pascal (1623-1662), the last thing one discovers in composing a work is what to put first. I would like to take the liberty of deviating from the tradition of the Philosophical Transactions and start with the tribute to Michael; after all he is the prime cause of this Theme Issue.

KENNEDY SPACE CENTER, FLA. -- From left, a United Space Alliance (USA) technician briefs NASA Deputy Program Manager of the Space Shuttle Program Michael Wetmore, USA Vice President and Space Shuttle Program Manager Howard DeCastro, and NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik on the use of cold plates in Orbiter Processing Facility Bay 2. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.

NASA Image and Video Library

2003-12-19

KENNEDY SPACE CENTER, FLA. -- From left, a United Space Alliance (USA) technician briefs NASA Deputy Program Manager of the Space Shuttle Program Michael Wetmore, USA Vice President and Space Shuttle Program Manager Howard DeCastro, and NASA Deputy Associate Administrator for Space Station and Shuttle Programs Michael Kostelnik on the use of cold plates in Orbiter Processing Facility Bay 2. NASA and USA Space Shuttle program management are participating in a leadership workday. The day is intended to provide management with an in-depth, hands-on look at Shuttle processing activities at KSC.

Energy Industry Powers CTE Program

ERIC Educational Resources Information Center

Khokhar, Amy

2012-01-01

Michael Fields is a recent graduate of Buckeye Union High School in Buckeye, Arizona. Fields is enrolled in the Estrella Mountain Community College (EMCC) Get Into Energy program, which means he is well on his way to a promising career. Specializing in power plant technology, in two years he will earn a certificate that will all but guarantee a…

Acrolein with an alpha, beta-unsaturated Carbonyl Group Inhibits LPS-induced Homodimerization of Toll-like Receptor 4

USDA-ARS?s Scientific Manuscript database

Acrolein is a highly electrophilic a,ß-unsaturated aldehyde present in a number of environmental sources, especially cigarette smoke. It reacts strongly with the thiol groups of cysteine residues by Michael addition and has been reported to inhibit nuclear factor-kB (NF-kB) activation by lipopolysac...

Amid Fiscal Crisis, L.A. Gives Site Councils Budget Reins

ERIC Educational Resources Information Center

Sawchuk, Stephen

2009-01-01

At Jefferson High School, a governing body made up of teachers, nonclassroom-based educators, parents, and Principal Michael Taft appears to be living the dream, to the extent such a thing is possible during a staggering fiscal crisis. The leadership team, officially known as a "school site council," has mainly used an infusion of…

Pledge Stays Intact as Justices Dismiss Atheist's Challenge

ERIC Educational Resources Information Center

Hendrie, Caroline

2004-01-01

This article reports on the fiery California atheist who lost his bid at the U.S. Supreme Court to get "under God" stricken from the Pledge of Allegiance. Dr. Michael A. Newdow, an emergency-room physician with a law degree who represented himself before the Supreme Court in the high-profile case against the Elk Grove, California, school…

"It's Time": A Case for the Professionalisation of Youth Work

ERIC Educational Resources Information Center

Emslie, Michael

2012-01-01

Michael Emslie argues that the time is right for youth work in Australia to be professionalised in line with other human service practices such as nursing, education and psychology. He identifies a groundswell of activities that support the professionalisation of youth work and a concurrent growth in high-level interest in strengthening social and…

Hexamethoxylated Monocarbonyl Analogues of Curcumin Cause G2/M Cell Cycle Arrest in NCI-H460 Cells via Michael Acceptor-Dependent Redox Intervention.

PubMed

Li, Yan; Zhang, Li-Ping; Dai, Fang; Yan, Wen-Jing; Wang, Hai-Bo; Tu, Zhi-Shan; Zhou, Bo

2015-09-09

Curcumin, derived from the dietary spice turmeric, holds promise for cancer prevention. This prompts much interest in investigating the action mechanisms of curcumin and its analogues. Two symmetrical hexamethoxy-diarylpentadienones (1 and 2) as cucumin analogues were reported to possess significantly enhanced cytotoxicity compared with the parent molecule. However, the detailed mechanisms remain unclear. In this study, compounds 1 and 2 were identified as the G2/M cell cycle arrest agents to mediate the cytotoxicity toward NCI-H460 cells via Michael acceptor-dependent redox intervention. Compared with curcumin, they could more easily induce a burst of reactive oxygen species (ROS) and collapse of the redox buffering system. One possible reason is that they could more effectively target intracellular TrxR to convert this antioxidant enzyme into a ROS promoter. Additionally, they caused up-regulation of p53 and p21 and down-regulation of redox-sensitive Cdc25C along with cyclin B1/Cdk1 in a Michael acceptor- and ROS-dependent fashion. Interestingly, in comparison with compound 2, compound 1 displayed a relatively weak ability to generate ROS but increased cell cycle arrest activity and cytotoxicity probably due to its Michael acceptor-dependent microtubule-destabilizing effect and greater GST-inhibitory activity, as well as its enhanced cellular uptake. This work provides useful information for understanding Michael acceptor-dependent and redox-mediated cytotoxic mechanisms of curcumin and its active analogues.

Fatigue Performance under Multiaxial Loading

DTIC Science & Technology

1990-01-01

Director, Structural Integrity Engineering Officer (N7) Subgroup ( SEA 55Y) Military Seaift Command Naval Sea Systems Command Dr. Donald Liu CDR Michael K...REPRESENTATIVES Mr. William J. Siekierka Mr. Greg D. Woods SEA 55Y3 SEA 55Y3 Naval Sea Systems Command Naval Sea Systems Command SHIP STRUCTURE...AMERICAN BUREAU OF SHIPPING NAVAL SEA SYSTEMS COMMAND Mr. Stephen G. Arntson (Chairman) Mr. Robert A. Sielski Mr. John F. Conlon Mr. Charles L. Null Mr

Society and the British Army: Implications for Fighting Spirit

DTIC Science & Technology

2017-05-25

5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) U.S. Army Command and General Staff College ATTN: ATZL-SWD-GD Fort...retaining support amongst all segments of society. Failure to do so will negate the cross- fertilization to which Hawley refers. The ethos need not exactly...Geert Hofstede, Gert Jan Hofstede, and Michael Minkov, Cultures and Organizations : Software of the Mind (New York: The McGraw-Hill Companies, 2010

Foale works with the Pilot experiment during Expedition 8

NASA Image and Video Library

2003-10-31

ISS008-E-05181 (31 October 2003) --- Astronaut C. Michael Foale, Expedition 8 mission commander and NASA ISS science officer, works with the Russian biomedical “Pilot” experiment (MBI-15) in the Zvezda Service Module on the International Space Station (ISS). The experiment, which looks at psychological and physiological changes in crew performance during long-duration spaceflight, requires a worktable, ankle restraint system and two control handles for testing piloting skill.

Speaker Recognition Using Real vs. Synthetic Parallel Data for DNN Channel Compensation

DTIC Science & Technology

2016-09-08

Speaker Recognition Using Real vs Synthetic Parallel Data for DNN Channel Compensation Fred Richardson, Michael Brandstein, Jennifer Melot, and...DNNs trained with real Mixer 2 multichannel data perform only slightly better than DNNs trained with synthetic multichannel data for microphone SR on...Mixer 6. Large re- ductions in pooled error rates of 50% EER and 30% min DCF are achieved using DNNs trained on real Mixer 2 data. Nearly the same

Preliminary Work on the Command and Control Workstation of the Future

DTIC Science & Technology

1988-06-01

THE COMMAND AND CONTROL WORKSTATION OF THE FUTURE by Frank E. Harris June 1988 Thesis Advisor: Michael J. Zyda Approved for public release; Distribution...DApproved for public release; 2b DECLASSIFICATIONDOWNGRADING SCHEDULE Distribution is unlimited 0 4 PERFORMING ORGAN!ZATION REPORT NUMBER(S) 5 MONITORING...information, allowin the commander to choose the information that is most pertinent to the decisio s he must makd at that time. This e i-f the

Impact of Retirement Choices of Early Career Marines: A Choice Analysis Model

DTIC Science & Technology

2013-03-01

CHOICES OF EARLY CAREER MARINES: A CHOICE ANALYSIS MODEL by André G. La Taste Aaron Masaitis March 2013 Thesis Advisor: Michael Dixon... ANALYSIS MODEL 5. FUNDING NUMBERS 6. AUTHOR(S) André G. La Taste, Aaron Masaitis 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate...system. The research will be conducted using a discrete choice analysis methodology that is often used to differentiate factors that lead to

Languages for Software-Defined Networks

DTIC Science & Technology

2013-02-01

1 Languages for Software-Defined Networks Nate Foster∗, Michael J. Freedman†, Arjun Guha∗, Rob Harrison‡, Naga Praveen Katta†, Christopher Monsanto ...2012. [12] “The Frenetic project.” http://www.frenetic-lang.org/, Sept. 2012. [13] N. Foster, R. Harrison, M. J. Freedman, C. Monsanto , J. Rexford...performance networks,” in ACM SIGCOMM, pp. 254–265, Aug. 2011. [15] C. Monsanto , N. Foster, R. Harrison, and D. Walker, “A compiler and run-time system for

Craney Island Disposal Area. Site Operations and Monitoring Report, 1980-1987

DTIC Science & Technology

1990-07-01

STCFITE nmpyv FMISCELLANEOUS PAPER EL-90-10 * * *CRANEY ISLAND DISPOSAL AREA SITE OPERATIONS AND MONITORING REPORT, 1980-1987 N by Michael R. Palermo...4. PERFORMING ORGANIZATION REPORT NUMBER(S) 5. MONITORING ORGANIZATION REPORT NUMBER(S) Miscellaneous Paper EL-90-0 0 So. M OF :RFRMING ORGANIZATION...area is a 2,500-acre confined dredged material disposal facility located near Norfolk, VA. In 1981, the Craney Island Management Plan ( CIMP ) was

Improving Intelligence Integration Amongst the Intelligence Community

DTIC Science & Technology

2014-06-13

numerous attacks because of the work of the men and women in the IC. Success in the IC goes unrecognized while failure becomes public knowledge...ELEMENT NUMBER 6. AUTHOR(S) Michael D. Norton, MAJ, USA 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING...the process. His lifelong dedication to research and teaching enabled me the freedom to work the project knowing he was a simple call away. Dr. House

An Architecture for the Semantic Processing of Natural Language Input to a Policy Workbench

DTIC Science & Technology

2003-03-01

WORKBENCH by E. John Custy March 2003 Thesis Advisor: J. Bret Michael Co-Advisor: Neil C. Rowe Approved for...Policy Workbench 6. AUTHOR(S) E. John Custy 5. FUNDING NUMBERS 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School Monterey...POLICY WORKBENCH E. John Custy B.S.E.E. New Jersey Institute of Technology, 1986 M.A. Cognitive and Neural Systems, Boston University, 1991 Master of

Comparison between Hydrogen and Methane Fuels in a 3-D Scramjet at Mach 8

DTIC Science & Technology

2016-06-24

performance of small chained hydrocarbons ( ethylene and methane) was compared with hydrogen to establish the importance of its lower specific energy...Report Comparison between hydrogen, methane and ethylene fuels in a 3-D Scramjet at Mach 8 Professor Michael K. Smart Chair of Hypersonic Propulsion...hydrocarbons ( ethylene and methane) was compared with hydrogen to establish the importance of its lower specific energy content and slower reaction

Little Mosie from the Margaree: A Biography of Moses Michael Coady.

ERIC Educational Resources Information Center

Welton, Michael R.

This book examines the life of the Reverend Moses Michael Coady (1890-1959), a Roman Catholic priest who led the Antigonish Movement. During the Antigonish Movement, residents of the small maritime town of Antigonish, Nova Scotia, worked to achieve a nonviolent alternative to communism and fascism and to effect the social and economic…

78 FR 68102 - Atomic Safety and Licensing Board; In the Matter of Nuclear Innovation North America LLC (South...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-13

...] Atomic Safety and Licensing Board; In the Matter of Nuclear Innovation North America LLC (South Texas... Administrative Judges: Michael M. Gibson, Chairman, Dr. Gary S. Arnold, Dr. Randall J. Charbeneau. The Atomic... follows: Mail: Administrative Judge Michael M. Gibson, Atomic Safety and Licensing Board Panel, Mail Stop...

The United Kingdom Children's Laureate: The Story so Far

ERIC Educational Resources Information Center

Tucker, Nicholas

2014-01-01

Britain's Children's Laureate Scheme has now been running for 14 years. This article asks Quentin Blake, Anne Fine, Michael Morpurgo, Jacqueline Wilson, Anthony Browne, Michael Rosen and Julia Donaldson for their views on their own experience of taking up this post. It concludes with a discussion of the recurring issues raised by these Laureates…

A tribute to Michael R. Raupach for contributions to aeolian fluid dynamics

USDA-ARS?s Scientific Manuscript database

Since the early work of Bagnold in the 1940s, aeolian research has grown to become a major integral part of earth-system studies. Many individuals have contributed to this development, and Dr. Michael R. Raupach (MR2, 1950 – 2015) was one of the most outstanding. MR2 worked for about a decade (1985 ...

Defining Deviance: Sex, Science, and Delinquent Girls, 1890-1960

ERIC Educational Resources Information Center

Clemente, Michael

2013-01-01

This article presents a review on "Defining deviance: sex, science, and delinquent girls, 1890-1960," by Michael A. Rembis. This is the first book by Michael A. Rembis, an Associate Professor and Director of the Center for Disability Studies at the University of Buffalo. Drawing on thousands of case files from the Illinois State Training School in…

Cloud Migration Experiment Configuration and Results

DTIC Science & Technology

2017-12-01

ARL-TR-8248 ● DEC 2017 US Army Research Laboratory Cloud Migration Experiment Configuration and Results by Michael De Lucia...or reconstruction of the document. ARL-TR-8248 ● DEC 2017 US Army Research Laboratory Cloud Migration Experiment Configuration...and Results by Michael De Lucia Computational and Information Sciences Directorate, ARL Justin Wray and Steven S Collmann ICF International

Michael Young's "The Rise of the Meritocracy": A Philosophical Critique

ERIC Educational Resources Information Center

Allen, Ansgar

2011-01-01

This paper examines Michael Young's 1958 dystopia, "The Rise of the Meritocracy". In this book, the word "meritocracy" was coined and used in a pejorative sense. Today, however, meritocracy represents a positive ideal against which we measure the justice of our institutions. This paper argues that, when read in the twenty-first century, Young's…

Freedom of Information Act Requests: Six Keys to Handling Them

DTIC Science & Technology

2016-01-01

Defense AT&L: January–February 2016 50 Freedom of Information Act Requests Six Keys to Handling Them Michael A. Rodgers Rodgers is a professor of...crucial mission tasks. Understanding and using the six steps and keys provided above will free you from FOIA-induced distractions. The author can be contacted at michael.rodgers@dau.mil.

Q & A with Ed Tech Leaders: Interview with Michael W. Allen

ERIC Educational Resources Information Center

Shaughnessy, Michael F.

2014-01-01

Michael W. Allen, the Chairman and CEO of Allen Interactions, is an architect of interactive multimedia learning and is recognized for his many insights, inventions, and presentations. With over 50 years of experience in e-learning, both in academic and corporate settings, he is known for his role in creating Authorware and overseeing the work of…

Gulliver's Travels: Michael Moore the Explorer in "Who to Invade Next"

ERIC Educational Resources Information Center

Beck, Bernard

2016-01-01

America is identified as a nation of immigrants. These immigrants are thought to be the source of its subcultures. It is also a nation of individual explorers and inventors. Their activities are also a source of diverse subcultures. Many notable movies have made heroes of such innovators in different fields of endeavor. Michael Moore's movie…

Irish Education for the 21st Century. Michael Enright Commemorative Project.

ERIC Educational Resources Information Center

Ward, Noel, Ed.; Dooney, Triona, Ed.

The essays in this collection contribute to the ongoing discussion about the state of Irish education on the threshold of a new century. The various contributors examine issues that will be priorities for education planners in Ireland. These essays have been collected as a tribute to Irish educator and politician Michael Enright. The essays are:…

The Benevolent Technocrat: Michael Dukakis' Strategy in the 1988 Presidential Debates.

ERIC Educational Resources Information Center

Herbeck, Dale A.

Michael Dukakis lost the presidential campaign debates of 1988 (or at least failed to capitalize as much as he might have) because he understood the debates to be genuine debates. Consequently, Dukakis acted as a debater generating an image of himself as a "benevolent technocrat," which was an error. It must be pointed out that the…

Wolff-Michael Roth's passibility: at the limits of the constructivist metaphor: a book review

NASA Astrophysics Data System (ADS)

Brendel, Michelle

2014-12-01

Wolff-Michael Roth deconstructs the preeminent role conceded to constructivism in Science Education and demonstrates how we learn and know through pain, suffering, love or passion. This review explores his book "Passibility: At the Limits of the Constructivist Metaphor" through the eyes of an outsider to the world of science education.

Technique Development Results for the Study of a Novel Dexamethasone Impregnated Bandage Contact Lens in a Rabbit Model After Photorefractive Keratectomy

DTIC Science & Technology

2017-10-22

PRK Inflammation in a Rabbit Model Timothy A. Soekenl, Michael Merkley!, Wesley Brundridgel, Gary Legaultl, Matthew Caldwelll, Joseph Ciolino2...7 .0 Dexamethasone Impregnated Contact Lenses in the Treatment of Post- PRK Inflammation · in a Rabbit Model Timothy A. Soeken 1, Michael Merkley1

Michael's Inform Test of Student Ability (M.I.T.O.S.A.). Tester's Manual.

ERIC Educational Resources Information Center

Grafius, Thomas M.

Michael's Informal Test of Student Ability (MITOSA) is a diagnostic evaluative tool for adult students designed to test nine skills abilities in adult students functioning below a tenth grade level. The nine test sections are approximate reading level, understanding of basic math concepts and symbols, general thinking/reasoning ability, eye-hand…

Moral Education and Education in Altruism: Two Replies to Michael Hand

ERIC Educational Resources Information Center

White, John

2016-01-01

This article is a critical discussion of two recent papers by Michael Hand on moral education. The first is his "Towards a Theory of Moral Education", published in the "Journal of Philosophy of Education" in 2014 (Volume 48, Issue 4). The second is a chapter called "Beyond Moral Education?" in an edited book of new…

Astronaut C. Michael Foale is briefed on use of Sky Genie

NASA Technical Reports Server (NTRS)

1994-01-01

Astronaut C. Michael Foale, STS-63 mission specialist, is briefed on the use of Sky Genie device by Karin L. Porter. The device would aid in emergency egress operations aboard a troubled Space Shuttle. Porter, an employee of Rockwell International, helps train astronauts in egress procedures at JSC's Shuttle mockup and integration laboratory.

A Critical Analysis of Michael Tippett's "A Child of Our Time"

ERIC Educational Resources Information Center

Vallee, Jean-Sebastien

2009-01-01

After more than ten years of thoughtful planning, Michael Tippett (1905-1998) summed up his musical, political, spiritual and philosophical beliefs in his first oratorio, "A Child of Our Time" (1941). Representing the emergence of a new level of confidence and musical maturity for Tippett, the oratorio has become the composer's most widely known…

Michael Griffin Oath Of Office

NASA Image and Video Library

2005-04-14

NASA Administrator Michael Griffin, left, is administered the oath of office by John H. Marburger, right, Science Adviser to the President and Office of Science and Technology Policy Director, during a private ceremony at the Old Executive Office Building, Thursday, April 14, 2005, in Washington, while his wife Rebecca and daughter Katie look on. Photo Credit: (NASA/Renee Bouchard)

A Teacher's Guide to Rerouting the Pipeline

ERIC Educational Resources Information Center

Chiariello, Emily

2013-01-01

Michael is 15 and repeating the ninth grade. He habitually tilts his chair back and drums annoyingly on his desk with a pencil. This morning, he was doing it--again--while you were trying to teach. What will you do? Responsive teachers shift their reactions in important ways. They adopt a social emotional lens: What does Michael's tapping say…

Software Technology for Adaptable Reliable Systems (STARS) Workshop Held at the Naval Research Laboratory, Washington, DC on April 9-12 1985

DTIC Science & Technology

1985-01-01

paths? .%* vii * * ... * r -. . . .W. -t. ’ PREFACE ......... H*o . .. . ON.........................NT .. . . . . . . . . . . ............ . ........... l...REUSE ................................................ 83 Dr. Bruce A. Burton and Mr. Michael D. Broido REUSABLE COMPONENT DEFINITION (A TUTORIAL...209 Michael R . Miller, Hans L. Hiabereder, and L.O. Keeler REUSABLE SOFTWARE IN SIMULATION APPLICATIONS

Facile Iodine-Catalyzed Michael Addition of Indoles to α,α′-Bis(arylmethylene)cyclopentanones: An Efficient Synthesis of E-2-(3-Indolylphenylmethyl)-5-phenylmethylenecyclopentanones

PubMed Central

Pal, Rammohan; Das Gupta, Arpita; Mallik, Asok K.

2012-01-01

Iodine-catalyzed reaction of indoles with α,α′-bis(arylmethylene)cyclopentanones afforded one diastereomer of the corresponding Michael adducts, namely, E-2-(3-indolylphenylmethyl)-5-phenylmethylenecyclopentanones, in a good yield. The products form a new group of indole derivatives. PMID:24052849

What Work Do the Concepts of "Language" and "Literature" Do for Michael Rosenak?

ERIC Educational Resources Information Center

Levisohn, Jon A.

2014-01-01

Michael Rosenak uses the twin metaphors of "language" and "literature," borrowed from Oakeshott and Peters, to argue that the goal of education is initiation into a language. This goal transcends the study of literature in that language. It includes, as well, the development of the capacity both to critique literature and to…

Education, Philosophy and Politics: The Selected Works of Michael A. Peters. World Library of Educationalists

ERIC Educational Resources Information Center

Peters, Michael A.

2012-01-01

In the World Library of Educationalists series, international experts themselves compile career-long collections of what they judge to be their finest pieces--extracts from books, key articles, salient research findings, major theoretical and/practical contributions--so the world can read them in a single manageable volume. Michael A. Peters has…

Subjectivity and Cultural Adjustment in Mathematics Education: A Response to Wolff-Michael Roth

ERIC Educational Resources Information Center

Brown, Tony

2012-01-01

In this volume, Wolff-Michael Roth provides a critical but partial reading of Tony Brown's book "Mathematics Education and Subjectivity". The reading contrasts Brown's approach with Roth's own conception of subjectivity as derived from the work of Vygotsky, in which Roth aims to "reunite" psychology and sociology. Brown's book, however, focuses on…