Sample records for high quality source

  1. Sources of practice knowledge among Australian fitness trainers.

    PubMed

    Bennie, Jason A; Wiesner, Glen H; van Uffelen, Jannique G Z; Harvey, Jack T; Biddle, Stuart J H

    2017-12-01

    Few studies have examined the sources of practice knowledge fitness trainers use to inform their training methods and update knowledge. This study aims to describe sources of practice knowledge among Australian fitness trainers. In July 2014, 9100 Australian fitness trainers were invited to complete an online survey. Respondents reported the frequency of use of eight sources of practice knowledge (e.g. fitness magazines, academic texts). In a separate survey, exercise science experts (n = 27) ranked each source as either (1) 'high-quality' or (2) 'low-quality'. Proportions of users of 'high-quality' sources were calculated across demographic (age, sex) and fitness industry-related characteristics (qualification, setting, role). A multivariate logistic regression analysis assessed the odds of being classified as a user of high-quality sources, adjusting for demographic and fitness industry-related factors. Out of 1185 fitness trainers (response rate = 13.0%), aged 17-72 years, 47.6% (95% CI, 44.7-50.4%) were classified as frequent users of high-quality sources of practice knowledge. In the adjusted analysis, compared to trainers aged 17-26 years, those aged ≥61 years (OR, 2.15; 95% CI, 1.05-4.38) and 40-50 years (OR, 1.54; 95% CI, 1.02-2.31) were more likely to be classified as a user of high-quality sources. When compared to trainers working in large centres, those working in outdoor settings (OR, 1.81; 95% CI, 1.23-2.65) and medium centres (OR, 1.59; 95% CI, 1.12-2.29) were more likely to be classified as users of high-quality sources. Our findings suggest that efforts should be made to improve the quality of knowledge acquisition among Australian fitness trainers.

  2. Effects of argument quality, source credibility and self-reported diabetes knowledge on message attitudes: an experiment using diabetes related messages.

    PubMed

    Lin, Tung-Cheng; Hwang, Lih-Lian; Lai, Yung-Jye

    2017-05-17

    Previous studies have reported that credibility and content (argument quality) are the most critical factors affecting the quality of health information and its acceptance and use; however, this causal relationship merits further investigation in the context of health education. Moreover, message recipients' prior knowledge may moderate these relationships. This study used the elaboration likelihood model to determine the main effects of argument quality, source credibility and the moderating effect of self-reported diabetes knowledge on message attitudes. A between-subjects experimental design using an educational message concerning diabetes for manipulation was applied to validate the effects empirically. A total of 181 participants without diabetes were recruited from the Department of Health, Taipei City Government. Four group messages were manipulated in terms of argument quality (high and low) × source credibility (high and low). Argument quality and source credibility of health information significantly influenced the attitude of message recipients. The participants with high self-reported knowledge participants exhibited significant disapproval for messages with low argument quality. Effective health information should provide objective descriptions and cite reliable sources; in addition, it should provide accurate, customised messages for recipients who have high background knowledge level and ability to discern message quality. © 2017 Health Libraries Group Health Information & Libraries Journal.

  3. Comprehension and Writing Strategy Training Improves Performance on Content-Specific Source-Based Writing Tasks

    ERIC Educational Resources Information Center

    Weston-Sementelli, Jennifer L.; Allen, Laura K.; McNamara, Danielle S.

    2016-01-01

    Source-based essays are evaluated both on the quality of the writing and the content appropriate interpretation and use of source material. Hence, composing a high-quality source-based essay (an essay written based on source material) relies on skills related to both reading (the sources) and writing (the essay) skills. As such, source-based…

  4. Comprehension and Writing Strategy Training Improves Performance on Content-Specific Source-Based Writing Tasks

    ERIC Educational Resources Information Center

    Weston-Sementelli, Jennifer L.; Allen, Laura K.; McNamara, Danielle S.

    2018-01-01

    Source-based essays are evaluated both on the quality of the writing and the content appropriate interpretation and use of source material. Hence, composing a high-quality source-based essay (an essay written based on source material) relies on skills related to both reading (the sources) and writing (the essay) skills. As such, source-based…

  5. Quality Analysis of Open Street Map Data

    NASA Astrophysics Data System (ADS)

    Wang, M.; Li, Q.; Hu, Q.; Zhou, M.

    2013-05-01

    Crowd sourcing geographic data is an opensource geographic data which is contributed by lots of non-professionals and provided to the public. The typical crowd sourcing geographic data contains GPS track data like OpenStreetMap, collaborative map data like Wikimapia, social websites like Twitter and Facebook, POI signed by Jiepang user and so on. These data will provide canonical geographic information for pubic after treatment. As compared with conventional geographic data collection and update method, the crowd sourcing geographic data from the non-professional has characteristics or advantages of large data volume, high currency, abundance information and low cost and becomes a research hotspot of international geographic information science in the recent years. Large volume crowd sourcing geographic data with high currency provides a new solution for geospatial database updating while it need to solve the quality problem of crowd sourcing geographic data obtained from the non-professionals. In this paper, a quality analysis model for OpenStreetMap crowd sourcing geographic data is proposed. Firstly, a quality analysis framework is designed based on data characteristic analysis of OSM data. Secondly, a quality assessment model for OSM data by three different quality elements: completeness, thematic accuracy and positional accuracy is presented. Finally, take the OSM data of Wuhan for instance, the paper analyses and assesses the quality of OSM data with 2011 version of navigation map for reference. The result shows that the high-level roads and urban traffic network of OSM data has a high positional accuracy and completeness so that these OSM data can be used for updating of urban road network database.

  6. [Effect of spermatozoa from different sources on normal fertilization of oocytes and embryo quality and development in intracytoplasmic sperm injection cycles].

    PubMed

    Xie, Duo; Qiu, Zhuolin; Luo, Chen; Chu, Qingjun; Quan, Song

    2014-06-01

    To evaluate the impact of spermatozoa from different sources on normal fertilization of oocytes, embryo quality and embryo developmental potential in intracytoplasmic sperm injection (ICSI) cycles. A retrospective analysis was conducted among 197 patients undergoing ICSI cycles in our center. The patients were classified into 3 groups according to the sources of semen, namely ejaculated spermatozoa group (n=102), percutaneous epididymal sperm aspiration (PESA) group (n=68), and testicular sperm aspiration (TESA) group (n=27). The ejaculated spermatozoa group was further classified into oligoasthenoteratozoospermia (n=67) and cryptozoospermia (n=35) subgroups. The normal fertilization, high-quality embryo, implantation and clinical pregnancy rates were compared among the groups; the rate of high-quality blastocyst formation in in-vitro culture of non-top quality embryos was also observed. The patients with PESA showed significantly higher normal fertilization rate (75.6%) than those in oligoasthenoteratozoospermia (64.8%), cryptozoospermia (62.1%), and TESA (61.6%) groups (P<0.05). No significant differences were found in the high-quality embryo, implantation, and clinical pregnancy rates among the groups (P>0.05). The rate of high-quality blastocyst formation in the in-vitro culture of non-top quality embryos was also comparable among the groups (P>0.05). Although spermatozoa obtained with by PESA is associated with a higher normal fertilization rate, the sources of spermatozoa do not significantly affect the embryonic quality and developmental potential in ICSI cycles.

  7. Assessing product image quality for online shopping

    NASA Astrophysics Data System (ADS)

    Goswami, Anjan; Chung, Sung H.; Chittar, Naren; Islam, Atiq

    2012-01-01

    Assessing product-image quality is important in the context of online shopping. A high quality image that conveys more information about a product can boost the buyer's confidence and can get more attention. However, the notion of image quality for product-images is not the same as that in other domains. The perception of quality of product-images depends not only on various photographic quality features but also on various high level features such as clarity of the foreground or goodness of the background etc. In this paper, we define a notion of product-image quality based on various such features. We conduct a crowd-sourced experiment to collect user judgments on thousands of eBay's images. We formulate a multi-class classification problem for modeling image quality by classifying images into good, fair and poor quality based on the guided perceptual notions from the judges. We also conduct experiments with regression using average crowd-sourced human judgments as target. We compute a pseudo-regression score with expected average of predicted classes and also compute a score from the regression technique. We design many experiments with various sampling and voting schemes with crowd-sourced data and construct various experimental image quality models. Most of our models have reasonable accuracies (greater or equal to 70%) on test data set. We observe that our computed image quality score has a high (0.66) rank correlation with average votes from the crowd sourced human judgments.

  8. Growth and Photovoltaic Properties of High-Quality GaAs Nanowires Prepared by the Two-Source CVD Method.

    PubMed

    Wang, Ying; Yang, Zaixing; Wu, Xiaofeng; Han, Ning; Liu, Hanyu; Wang, Shuobo; Li, Jun; Tse, WaiMan; Yip, SenPo; Chen, Yunfa; Ho, Johnny C

    2016-12-01

    Growing high-quality and low-cost GaAs nanowires (NWs) as well as fabricating high-performance NW solar cells by facile means is an important development towards the cost-effective next-generation photovoltaics. In this work, highly crystalline, dense, and long GaAs NWs are successfully synthesized using a two-source method on non-crystalline SiO2 substrates by a simple solid-source chemical vapor deposition method. The high V/III ratio and precursor concentration enabled by this two-source configuration can significantly benefit the NW growth and suppress the crystal defect formation as compared with the conventional one-source system. Since less NW crystal defects would contribute fewer electrons being trapped by the surface oxides, the p-type conductivity is then greatly enhanced as revealed by the electrical characterization of fabricated NW devices. Furthermore, the individual single NW and high-density NW parallel arrays achieved by contact printing can be effectively fabricated into Schottky barrier solar cells simply by employing asymmetric Ni-Al contacts, along with an open circuit voltage of ~0.3 V. All these results indicate the technological promise of these high-quality two-source grown GaAs NWs, especially for the realization of facile Schottky solar cells utilizing the asymmetric Ni-Al contact.

  9. Adolescent HIV Prevention: An Application of the Elaboration Likelihood Model.

    ERIC Educational Resources Information Center

    Metzler, April E.; Weiskotten, David; Morgen, Keith J.

    Ninth grade students (n=298) participated in a study to examine the influence source credibility, message, quality, and personal relevance on HIV prevention message efficacy. A pilot study with adolescent focus groups created the high and low quality messages, as well as the high (HIV+) and low (worried parent) credibility sources. Participants…

  10. Epitaxial Deposition Of Germanium Doped With Gallium

    NASA Technical Reports Server (NTRS)

    Huffman, James E.

    1994-01-01

    Epitaxial layers of germanium doped with gallium made by chemical vapor deposition. Method involves combination of techniques and materials used in chemical vapor deposition with GeH4 or GeCl4 as source of germanium and GaCl3 as source of gallium. Resulting epitaxial layers of germanium doped with gallium expected to be highly pure, with high crystalline quality. High-quality material useful in infrared sensors.

  11. Assessing the microbial quality of improved drinking water sources: results from the Dominican Republic.

    PubMed

    Baum, Rachel; Kayser, Georgia; Stauber, Christine; Sobsey, Mark

    2014-01-01

    Millennium Development Goal Target 7c (to halve between 1990 and 2015 the proportion of the global population without sustainable access to safe drinking water), was celebrated as achieved in 2012. However, new studies show that we may be prematurely celebrating. Access to safe drinking water may be overestimated if microbial water quality is considered. The objective of this study was to examine the relationship between microbial drinking water quality and drinking water source in the Puerto Plata region of the Dominican Republic. This study analyzed microbial drinking water quality data from 409 households in 33 communities. Results showed that 47% of improved drinking water sources were of high to very-high risk water quality, and therefore unsafe for drinking. This study provides evidence that the current estimate of safe water access may be overly optimistic, and microbial water quality data are needed to reliably assess the safety of drinking water.

  12. Assessing the Microbial Quality of Improved Drinking Water Sources: Results from the Dominican Republic

    PubMed Central

    Baum, Rachel; Kayser, Georgia; Stauber, Christine; Sobsey, Mark

    2014-01-01

    Millennium Development Goal Target 7c (to halve between 1990 and 2015 the proportion of the global population without sustainable access to safe drinking water), was celebrated as achieved in 2012. However, new studies show that we may be prematurely celebrating. Access to safe drinking water may be overestimated if microbial water quality is considered. The objective of this study was to examine the relationship between microbial drinking water quality and drinking water source in the Puerto Plata region of the Dominican Republic. This study analyzed microbial drinking water quality data from 409 households in 33 communities. Results showed that 47% of improved drinking water sources were of high to very-high risk water quality, and therefore unsafe for drinking. This study provides evidence that the current estimate of safe water access may be overly optimistic, and microbial water quality data are needed to reliably assess the safety of drinking water. PMID:24218411

  13. Performance of turbo high-pitch dual-source CT for coronary CT angiography: first ex vivo and patient experience.

    PubMed

    Morsbach, Fabian; Gordic, Sonja; Desbiolles, Lotus; Husarik, Daniela; Frauenfelder, Thomas; Schmidt, Bernhard; Allmendinger, Thomas; Wildermuth, Simon; Alkadhi, Hatem; Leschka, Sebastian

    2014-08-01

    To evaluate image quality, maximal heart rate allowing for diagnostic imaging, and radiation dose of turbo high-pitch dual-source coronary computed tomographic angiography (CCTA). First, a cardiac motion phantom simulating heart rates (HRs) from 60-90 bpm in 5-bpm steps was examined on a third-generation dual-source 192-slice CT (prospective ECG-triggering, pitch 3.2; rotation time, 250 ms). Subjective image quality regarding the presence of motion artefacts was interpreted by two readers on a four-point scale (1, excellent; 4, non-diagnostic). Objective image quality was assessed by calculating distortion vectors. Thereafter, 20 consecutive patients (median, 50 years) undergoing clinically indicated CCTA were included. In the phantom study, image quality was rated diagnostic up to the HR75 bpm, with object distortion being 1 mm or less. Distortion increased above 1 mm at HR of 80-90 bpm. Patients had a mean HR of 66 bpm (47-78 bpm). Coronary segments were of diagnostic image quality for all patients with HR up to 73 bpm. Average effective radiation dose in patients was 0.6 ± 0.3 mSv. Our combined phantom and patient study indicates that CCTA with turbo high-pitch third-generation dual-source 192-slice CT can be performed at HR up to 75 bpm while maintaining diagnostic image quality, being associated with an average radiation dose of 0.6 mSv. • CCTA is feasible with the turbo high-pitch mode. • Turbo high-pitch CCTA provides diagnostic image quality up to 73 bpm. • The radiation dose of high-pitch CCTA is 0.6 mSv on average.

  14. Effects of wildfire on source-water quality and aquatic ecosystems, Colorado Front Range

    USGS Publications Warehouse

    Writer, Jeffrey H.; McCleskey, R. Blaine; Murphy, Sheila F.; Stone, Mike; Collins, Adrian; Thoms, Martin C.

    2012-01-01

    Watershed erosion can dramatically increase after wildfire, but limited research has evaluated the corresponding influence on source-water quality. This study evaluated the effects of the Fourmile Canyon wildfire (Colorado Front Range, USA) on source-water quality and aquatic ecosystems using high- frequency sampling. Dissolved organic carbon (DOC) and nutrient loads in stream water were evaluated for a one-year period during different types of runoff events, including spring snowmelt, and both frontal and summer convective storms. DOC export from the burned watershed did not increase relative to the unburned watershed during spring snowmelt, but substantial increases in DOC export were observed during summer convective storms. Elevated nutrient export from the burned watershed was observed during spring snowmelt and summer convective storms, which increased the primary productivity of stream biofilms. Wildfire effects on source-water quality were shown to be substantial following high-intensity storms, with the potential to affect drinking-water treatment processes.

  15. Relational Resources of a University as a Source of Education Quality Assurance

    ERIC Educational Resources Information Center

    Bagdasaryan, Irina; Vasilyeva, Zoya; Almabekova, Olga

    2015-01-01

    This paper considers high quality educational services provided by a university being the highest priority and assumes relational resources as valuable sources that can facilitate and enhance quality assurance. Each university with a unique resource base is connected with a variety of entities--other universities, non-profit and for-profit…

  16. Assessment of arsenic, fluoride, bacteria, and other contaminants in drinking water sources for rural communities of Kasur and other districts in Punjab, Pakistan.

    PubMed

    Arshad, Nasima; Imran, Saiqa

    2017-01-01

    High levels of arsenic contamination in drinking water of two villages, Badarpur and Ibrahimabad of district Kasur, central Punjab, Pakistan is reported first time in present studies. Groundwater quality situation was found to be impaired when samples of different rural areas of district Kasur were monitored according to Pakistan Standards and Quality Control Authority (PSQCA) for all significant water quality constituents and analyzed for trace elements, physico-chemical, and microbiological parameters. Out of 35water sources, 97 % were found unsafe and only 3 % of the sources were within safe limits. High concentrations of arsenic, fluoride, and bacteria were found in 91, 74, and 77 % sources of drinking water, respectively. Very high concentrations of arsenic ranging 58-3800 μg/L were found in the water samples obtained from Badarpur and Ibrahimabad. A decrease in water contamination was observed with increase in source depth. The health issues like arsenicosis and skeletal/dental flourosis were observed in the residents of the monitored areas. Drinking water quality conditions of some rural areas of northen and southern districts of Punjab was also analyzed and compared with Kasur district. High levels of nitrates were found in the samples of Islamabad and Rawalpindi, while high levels of arsenic, iron, fluoride, and TDS were found in Bahawalpur district. Graphical abstract ᅟ.

  17. Gain-guided soliton fiber laser with high-quality rectangle spectrum for ultrafast time-stretch microscopy.

    PubMed

    Hu, Song; Yao, Jian; Liu, Meng; Luo, Ai-Ping; Luo, Zhi-Chao; Xu, Wen-Cheng

    2016-05-16

    The ultrafast time-stretch microscopy has been proposed to enhance the temporal resolution of a microscopy system. The optical source is a key component for ultrafast time-stretch microscopy system. Herein, we reported on the gain-guided soliton fiber laser with high-quality rectangle spectrum for ultrafast time-stretch microscopy. By virtue of the excellent characteristics of the gain-guided soliton, the output power and the 3-dB bandwidth of the stable mode-locked soliton could be up to 3 mW and 33.7 nm with a high-quality rectangle shape, respectively. With the proposed robust optical source, the ultrafast time-stretch microscopy with the 49.6 μm resolution and a scan rate of 11 MHz was achieved without the external optical amplification. The obtained results demonstrated that the gain-guided soliton fiber laser could be used as an alternative high-quality optical source for ultrafast time-stretch microscopy and will introduce some applications in fields such as biology, chemical, and optical sensing.

  18. Avoiding Design Fixation: Transformation and Abstraction in Mapping from Source to Target

    ERIC Educational Resources Information Center

    Goldschmidt, Gabriela

    2011-01-01

    Designers try to "enlist" whatever they can to help themselves arrive at high quality, novel and original designs. When stimuli are used for this purpose, usually provided at the onset of the design process, these stimuli, or sources, may have one of two effects: they may enhance the design search and contribute to a high-quality, creative design,…

  19. Integrating multiple data sources in species distribution modeling: A framework for data fusion

    USGS Publications Warehouse

    Pacifici, Krishna; Reich, Brian J.; Miller, David A.W.; Gardner, Beth; Stauffer, Glenn E.; Singh, Susheela; McKerrow, Alexa; Collazo, Jaime A.

    2017-01-01

    The last decade has seen a dramatic increase in the use of species distribution models (SDMs) to characterize patterns of species’ occurrence and abundance. Efforts to parameterize SDMs often create a tension between the quality and quantity of data available to fit models. Estimation methods that integrate both standardized and non-standardized data types offer a potential solution to the tradeoff between data quality and quantity. Recently several authors have developed approaches for jointly modeling two sources of data (one of high quality and one of lesser quality). We extend their work by allowing for explicit spatial autocorrelation in occurrence and detection error using a Multivariate Conditional Autoregressive (MVCAR) model and develop three models that share information in a less direct manner resulting in more robust performance when the auxiliary data is of lesser quality. We describe these three new approaches (“Shared,” “Correlation,” “Covariates”) for combining data sources and show their use in a case study of the Brown-headed Nuthatch in the Southeastern U.S. and through simulations. All three of the approaches which used the second data source improved out-of-sample predictions relative to a single data source (“Single”). When information in the second data source is of high quality, the Shared model performs the best, but the Correlation and Covariates model also perform well. When the information quality in the second data source is of lesser quality, the Correlation and Covariates model performed better suggesting they are robust alternatives when little is known about auxiliary data collected opportunistically or through citizen scientists. Methods that allow for both data types to be used will maximize the useful information available for estimating species distributions.

  20. Quantifying the quality of precipitation data from different sources

    NASA Astrophysics Data System (ADS)

    Leijnse, Hidde; Wauben, Wiel; Overeem, Aart; de Haij, Marijn

    2015-04-01

    There is an increasing demand for high-resolution rainfall data. The current manual and automatic networks of climate and meteorological stations provide high quality rainfall data, but they cannot provide the high spatial and temporal resolution required for many applications. This can only partly be solved by using remotely sensed data. It is therefore necessary to consider third-party data, such as rain gauges operated by amateurs and rainfall intensities from commercial cellular communication links. The quality of such third-party data is highly variable and generally lower than that of dedicated networks. Often, such data quality information is missing for third party data. In order to be able to use data from various sources it is vital that quantitative knowledge of the data quality is available. This holds for all data sources, including the rain gauges in the reference networks of climate and meteorological stations. Data quality information is generally either not available or very limited for third-party data sources. For most dedicated climate meteorological networks, this information is only available for the sensor in laboratory conditions. In many cases, however, a significant part of the measurement errors and uncertainties is determined by the siting and maintenance of the sensor, for which generally only qualitative information is available. Furthermore sensors may have limitations under specific conditions. We aim to quantify data quality for different data sources by performing analyses on collocated data sets. Here we present an intercomparison of two years of precipitation data from six different sources (manual rain gauge, automatic rain gauge, present weather sensor, weather radar, commercial cellular communication links, and Meteosat) at three different locations in the Netherlands. We use auxiliary meteorological data to determine if the quality is influenced by other variables (e.g. the temperature influencing the evaporation from the rain gauge). We use three techniques to compare the data sets: 1) direct comparison; 2) triple collocation (see Stoffelen, 1998); and 3) comparison of statistics. Stoffelen, A. (1998). Toward the true near-surface wind speed: Error modeling and calibration using triple collocation. Journal of Geophysical Research: Oceans (1978-2012), 103(C4), 7755-7766.

  1. A post-implementation evaluation of ceramic water filters distributed to tsunami-affected communities in Sri Lanka.

    PubMed

    Casanova, Lisa M; Walters, Adam; Naghawatte, Ajith; Sobsey, Mark D

    2012-06-01

    Sri Lanka was devastated by the 2004 Indian Ocean tsunami. During recovery, the Red Cross distributed approximately 12,000 free ceramic water filters. This cross-sectional study was an independent post-implementation assessment of 452 households that received filters, to determine the proportion still using filters, household characteristics associated with use, and quality of household drinking water. The proportion of continued users was high (76%). The most common household water sources were taps or shallow wells. The majority (82%) of users used filtered water for drinking only. Mean filter flow rate was 1.12 L/hr (0.80 L/hr for households with taps and 0.71 for those with wells). Water quality varied by source; households using tap water had source water of high microbial quality. Filters improved water quality, reducing Escherichia coli for households (largely well users) with high levels in their source water. Households were satisfied with filters and are potentially long-term users. To promote sustained use, recovery filter distribution efforts should try to identify households at greatest long-term risk, particularly those who have not moved to safer water sources during recovery. They should be joined with long-term commitment to building supply chains and local production capacity to ensure safe water access.

  2. Low-cost, high-density sensor network for urban emission monitoring: BEACO2N

    NASA Astrophysics Data System (ADS)

    Kim, J.; Shusterman, A.; Lieschke, K.; Newman, C.; Cohen, R. C.

    2017-12-01

    In urban environments, air quality is spatially and temporally heterogeneous as diverse emission sources create a high degree of variability even at the neighborhood scale. Conventional air quality monitoring relies on continuous measurements with limited spatial resolution or passive sampling with high-density and low temporal resolution. Either approach averages the air quality information over space or time and hinders our attempts to understand emissions, chemistry, and human exposure in the near-field of emission sources. To better capture the true spatio-temporal heterogeneity of urban conditions, we have deployed a low-cost, high-density air quality monitoring network in San Francisco Bay Area distributed at 2km horizontal spacing. The BErkeley Atmospheric CO2 Observation Network (BEACO2N) consists of approximately 50 sensor nodes, measuring CO2, CO, NO, NO2, O­3, and aerosol. Here we describe field-based calibration approaches that are consistent with the low-cost strategy of the monitoring network. Observations that allow inference of emission factors and identification of specific local emission sources will also be presented.

  3. NON-POINT SOURCE POLLUTION

    EPA Science Inventory

    Non-point source pollution is a diffuse source that is difficult to measure and is highly variable due to different rain patterns and other climatic conditions. In many areas, however, non-point source pollution is the greatest source of water quality degradation. Presently, stat...

  4. Performance evaluation of a direct-conversion flat-panel detector system in imaging and quality assurance for a high-dose-rate 192Ir source

    NASA Astrophysics Data System (ADS)

    Miyahara, Yoshinori; Hara, Yuki; Nakashima, Hiroto; Nishimura, Tomonori; Itakura, Kanae; Inomata, Taisuke; Kitagaki, Hajime

    2018-03-01

    In high-dose-rate (HDR) brachytherapy, a direct-conversion flat-panel detector (d-FPD) clearly depicts a 192Ir source without image halation, even under the emission of high-energy gamma rays. However, it was unknown why iridium is visible when using a d-FPD. The purpose of this study was to clarify the reasons for visibility of the source core based on physical imaging characteristics, including the modulation transfer functions (MTF), noise power spectral (NPS), contrast transfer functions, and linearity of d-FPD to high-energy gamma rays. The acquired data included: x-rays, [X]; gamma rays, [γ] dual rays (X  +  γ), [D], and subtracted data for depicting the source ([D]  -  [γ]). In the quality assurance (QA) test for the positional accuracy of a source core, the coordinates of each dwelling point were compared between the planned and actual source core positions using a CT/MR-compatible ovoid applicator and a Fletcher-Williamson applicator. The profile curves of [X] and ([D]  -  [γ]) matched well on MTF and NPS. The contrast resolutions of [D] and [X] were equivalent. A strongly positive linear correlation was found between the output data of [γ] and source strength (r 2  >  0.99). With regard to the accuracy of the source core position, the largest coordinate difference (3D distance) was noted at the maximum curvature of the CT/MR-compatible ovoid and Fletcher-Williamson applicators, showing 1.74  ±  0.02 mm and 1.01  ±  0.01 mm, respectively. A d-FPD system provides high-quality images of a source, even when high-energy gamma rays are emitted to the detector, and positional accuracy tests with clinical applicators are useful in identifying source positions (source movements) within the applicator for QA.

  5. High power parallel ultrashort pulse laser processing

    NASA Astrophysics Data System (ADS)

    Gillner, Arnold; Gretzki, Patrick; Büsing, Lasse

    2016-03-01

    The class of ultra-short-pulse (USP) laser sources are used, whenever high precession and high quality material processing is demanded. These laser sources deliver pulse duration in the range of ps to fs and are characterized with high peak intensities leading to a direct vaporization of the material with a minimum thermal damage. With the availability of industrial laser source with an average power of up to 1000W, the main challenge consist of the effective energy distribution and disposition. Using lasers with high repetition rates in the MHz region can cause thermal issues like overheating, melt production and low ablation quality. In this paper, we will discuss different approaches for multibeam processing for utilization of high pulse energies. The combination of diffractive optics and conventional galvometer scanner can be used for high throughput laser ablation, but are limited in the optical qualities. We will show which applications can benefit from this hybrid optic and which improvements in productivity are expected. In addition, the optical limitations of the system will be compiled, in order to evaluate the suitability of this approach for any given application.

  6. Quality of water for livestock in man-made impoundments in the northern High Plains

    Treesearch

    Mark A. Rumble

    1985-01-01

    Twenty-seven water quality parameters were measured in coal surface mine impoundments, bentonite surface mine impoundments, and livestock ponds in the Northern High Plains. Most impoundments were safe for use as a source for livestock drinking water. Eight water quality parameters were different (a

  7. Multi-dimensional water quality assessment of an urban drinking water source elucidated by high resolution underwater towed vehicle mapping.

    PubMed

    Lock, Alan; Spiers, Graeme; Hostetler, Blair; Ray, James; Wallschläger, Dirk

    2016-04-15

    Spatial surveys of Ramsey Lake, Sudbury, Ontario water quality were conducted using an innovative underwater towed vehicle (UTV) equipped with a multi-parameter probe providing real-time water quality data. The UTV revealed underwater vent sites through high resolution monitoring of different spatial chemical characteristics using common sensors (turbidity, chloride, dissolved oxygen, and oxidation/reduction sensors) that would not be feasible with traditional water sampling methods. Multi-parameter probe vent site identification is supported by elevated alkalinity and silica concentrations at these sites. The identified groundwater vent sites appear to be controlled by bedrock fractures that transport water from different sources with different contaminants of concern. Elevated contaminants, such as, arsenic and nickel and/or nutrient concentrations are evident at the vent sites, illustrating the potential of these sources to degrade water quality. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Evaluating the message or the messenger? Implications for self-validation in persuasion.

    PubMed

    Clark, Jason K; Wegener, Duane T; Sawicki, Vanessa; Petty, Richard E; Briñol, Pablo

    2013-12-01

    Characteristics of persuasive message sources have been extensively studied. However, little attention has been paid to situations when people are motivated to form an evaluation of the communicator rather than the communicated issue. We postulated that these different foci can affect how a source validates message-related cognitions. Participants focused on the source (Studies 1 and 2) or the issue (Study 2) while reading weak or strong message arguments. Later, the communicator was described as low or high in credibility. When focused on the source, highly motivated participants were more confident and their attitudes were more reflective of thoughts when argument quality matched (e.g., weak arguments-low credibility) rather than mismatched (e.g., weak arguments-high credibility) source credibility. Conversely, when participants were focused on the issue, self-validation was greater when credibility was high rather than low-regardless of argument quality. Implications of these findings for the study and practice of persuasion are discussed.

  9. Dual-source spiral CT with pitch up to 3.2 and 75 ms temporal resolution: image reconstruction and assessment of image quality.

    PubMed

    Flohr, Thomas G; Leng, Shuai; Yu, Lifeng; Aiimendinger, Thomas; Bruder, Herbert; Petersilka, Martin; Eusemann, Christian D; Stierstorfer, Karl; Schmidt, Bernhard; McCollough, Cynthia H

    2009-12-01

    To present the theory for image reconstruction of a high-pitch, high-temporal-resolution spiral scan mode for dual-source CT (DSCT) and evaluate its image quality and dose. With the use of two x-ray sources and two data acquisition systems, spiral CT exams having a nominal temporal resolution per image of up to one-quarter of the gantry rotation time can be acquired using pitch values up to 3.2. The scan field of view (SFOV) for this mode, however, is limited to the SFOV of the second detector as a maximum, depending on the pitch. Spatial and low contrast resolution, image uniformity and noise, CT number accuracy and linearity, and radiation dose were assessed using the ACR CT accreditation phantom, a 30 cm diameter cylindrical water phantom or a 32 cm diameter cylindrical PMMA CTDI phantom. Slice sensitivity profiles (SSPs) were measured for different nominal slice thicknesses, and an anthropomorphic phantom was used to assess image artifacts. Results were compared between single-source scans at pitch = 1.0 and dual-source scans at pitch = 3.2. In addition, image quality and temporal resolution of an ECG-triggered version of the DSCT high-pitch spiral scan mode were evaluated with a moving coronary artery phantom, and radiation dose was assessed in comparison with other existing cardiac scan techniques. No significant differences in quantitative measures of image quality were found between single-source scans at pitch = 1.0 and dual-source scans at pitch = 3.2 for spatial and low contrast resolution, CT number accuracy and linearity, SSPs, image uniformity, and noise. The pitch value (1.6 pitch 3.2) had only a minor impact on radiation dose and image noise when the effective tube current time product (mA s/pitch) was kept constant. However, while not severe, artifacts were found to be more prevalent for the dual-source pitch = 3.2 scan mode when structures varied markedly along the z axis, particularly for head scans. Images of the moving coronary artery phantom acquired with the ECG-triggered high-pitch scan mode were visually free from motion artifacts at heart rates of 60 and 70 bpm. However, image quality started to deteriorate for higher heart rates. At equivalent image quality, the ECG-triggered high-pitch scan mode demonstrated lower radiation dose than other cardiac scan techniques on the same DSCT equipment (25% and 60% dose reduction compared to ECG-triggered sequential step-and-shoot and ECG-gated spiral with x-ray pulsing). A high-pitch (up to pitch = 3.2), high-temporal-resolution (up to 75 ms) dual-source CT scan mode produced equivalent image quality relative to single-source scans using a more typical pitch value (pitch = 1.0). The resultant reduction in the overall acquisition time may offer clinical advantage for cardiovascular, trauma, and pediatric CT applications. In addition, ECG-triggered high-pitch scanning may be useful as an alternative to ECG-triggered sequential scanning for patients with low to moderate heart rates up to 70 bpm, with the potential to scan the heart within one heart beat at reduced radiation dose.

  10. Comparison Between Prospectively Electrocardiogram-Gated High-Pitch Mode and Retrospectively Electrocardiogram-Gated Mode for Dual-Source CT Coronary Angiography.

    PubMed

    Koplay, Mustafa; Celik, Mahmut; Avcı, Ahmet; Erdogan, Hasan; Demir, Kenan; Sivri, Mesut; Nayman, Alaaddin

    2015-01-01

    We aimed to report the image quality, relationship between heart rate and image quality, amount of contrast agent given to the patients and radiation doses in coronary CT angiography (CTA) obtained by using high-pitch prospectively ECG-gated "Flash Spiral" technique (method A) or retrospectively ECG-gated technique (method B) using 128×2-slice dual-source CT. A total of 110 patients who were evaluated with method A and method B technique with a 128×2-detector dual-source CT device were included in the study. Patients were divided into three groups based on their heart rates during the procedure, and a relationship between heart rate and image quality were evaluated. The relationship between heart rate, gender and radiation dose received by the patients was compared. A total of 1760 segments were evaluated in terms of image quality. Comparison of the relationship between heart rate and image quality revealed a significant difference between heart rate <60 beats/min group and >75 beats/min group whereas <60 beats/min and 60-75 beats/min groups did not differ significantly. The average effective dose for coronary CTA was calculated as 1.11 mSv (0.47-2.01 mSv) for method A and 8.22 mSv (2.19-12.88 mSv) for method B. Method A provided high quality images with doses as low as <1 mSv in selected patients who have low heart rates with a high negative predictive value to rule out coronary artery disease. Although method B increases the amount of effective dose, it provides high diagnostic quality images for patients who have a high heart rate and arrhythmia which makes it is difficult to obtain images.

  11. Inverse compton light source: a compact design proposal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Deitrick, Kirsten Elizabeth

    In the last decade, there has been an increasing demand for a compact Inverse Compton Light Source (ICLS) which is capable of producing high-quality X-rays by colliding an electron beam and a high-quality laser. It is only in recent years when both SRF and laser technology have advanced enough that compact sources can approach the quality found at large installations such as the Advanced Photon Source at Argonne National Laboratory. Previously, X-ray sources were either high flux and brilliance at a large facility or many orders of magnitude lesser when produced by a bremsstrahlung source. A recent compact source wasmore » constructed by Lyncean Technologies using a storage ring to produce the electron beam used to scatter the incident laser beam. By instead using a linear accelerator system for the electron beam, a significant increase in X-ray beam quality is possible, though even subsequent designs also featuring a storage ring offer improvement. Preceding the linear accelerator with an SRF reentrant gun allows for an extremely small transverse emittance, increasing the brilliance of the resulting X-ray source. In order to achieve sufficiently small emittances, optimization was done regarding both the geometry of the gun and the initial electron bunch distribution produced off the cathode. Using double-spoke SRF cavities to comprise the linear accelerator allows for an electron beam of reasonable size to be focused at the interaction point, while preserving the low emittance that was generated by the gun. An aggressive final focusing section following the electron beam's exit from the accelerator produces the small spot size at the interaction point which results in an X-ray beam of high flux and brilliance. Taking all of these advancements together, a world class compact X-ray source has been designed. It is anticipated that this source would far outperform the conventional bremsstrahlung and many other compact ICLSs, while coming closer to performing at the levels found at large facilities than ever before. The design process, including the development between subsequent iterations, is presented here in detail, with the simulation results for this groundbreaking X-ray source.« less

  12. Quantifying tap-to-household water quality deterioration in urban communities in Vellore, India: The impact of spatial assumptions.

    PubMed

    Alarcon Falconi, Tania M; Kulinkina, Alexandra V; Mohan, Venkata Raghava; Francis, Mark R; Kattula, Deepthi; Sarkar, Rajiv; Ward, Honorine; Kang, Gagandeep; Balraj, Vinohar; Naumova, Elena N

    2017-01-01

    Municipal water sources in India have been found to be highly contaminated, with further water quality deterioration occurring during household storage. Quantifying water quality deterioration requires knowledge about the exact source tap and length of water storage at the household, which is not usually known. This study presents a methodology to link source and household stored water, and explores the effects of spatial assumptions on the association between tap-to-household water quality deterioration and enteric infections in two semi-urban slums of Vellore, India. To determine a possible water source for each household sample, we paired household and tap samples collected on the same day using three spatial approaches implemented in GIS: minimum Euclidean distance; minimum network distance; and inverse network-distance weighted average. Logistic and Poisson regression models were used to determine associations between water quality deterioration and household-level characteristics, and between diarrheal cases and water quality deterioration. On average, 60% of households had higher fecal coliform concentrations in household samples than at source taps. Only the weighted average approach detected a higher risk of water quality deterioration for households that do not purify water and that have animals in the home (RR=1.50 [1.03, 2.18], p=0.033); and showed that households with water quality deterioration were more likely to report diarrheal cases (OR=3.08 [1.21, 8.18], p=0.02). Studies to assess contamination between source and household are rare due to methodological challenges and high costs associated with collecting paired samples. Our study demonstrated it is possible to derive useful spatial links between samples post hoc; and that the pairing approach affects the conclusions related to associations between enteric infections and water quality deterioration. Copyright © 2016 Elsevier GmbH. All rights reserved.

  13. Feasibility of high-pitch spiral dual-source CT angiography in children with complex congenital heart disease compared to retrospective-gated spiral acquisition.

    PubMed

    Li, T; Zhao, S; Liu, J; Yang, L; Huang, Z; Li, J; Luo, C; Li, X

    2017-10-01

    To investigate the use of second-generation dual-source high-pitch computed tomography in obtaining confident diagnostic image quality using a low radiation dose in young patients with congenital heart disease (CHD). From July 2014 to June 2016, 50 consecutive children <4 years with complex CHD underwent electrocardiography (ECG)-triggered dual-source computed tomography (CT). The patients were assigned randomly to two groups: high-pitch (pitch 3.4) spiral dual-source CT acquisition (group A) and retrospectively spiral dual-source CT acquisition (group B). The image quality, diagnostic accuracy, coronary artery origin, course demonstration, and radiation exposure were compared between the two groups. Fifty examinations were performed (group A, 25; group B, 25). There were no significant differences in image quality, diagnostic accuracy, coronary artery origin, and course demonstration between the two groups. The image quality scores were 1.3±0.4 in group A and 1.1±0.3 in group B (p=0.2). The diagnostic accuracy was 100% in both groups. The coronary arteries were traceable in 80% in group A and 84% in group B (p=0.7). A single coronary artery was identified in one case in group A and the left anterior descending (LAD) branch originated from the right coronary artery (RCA) in one case in group B. There were significant differences in the effective doses between the two groups (0.40±0.20 mSv in group A and 2.7±1.0 mSv in group B, p<0.05). Intra-cardiac and extra-cardiac malformation, coronary artery origin, and course malformation can be visualised clearly using a high-pitch ECG-triggered dual-source CT with a low radiation dose and good image quality in patients with CHD. Copyright © 2017 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  14. 40 CFR 131.35 - Colville Confederated Tribes Indian Reservation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...-effective and reasonable best management practices for nonpoint source control. (iii) Where high quality... within areas designated as unique water quality management areas and waters otherwise of exceptional... PROGRAMS WATER QUALITY STANDARDS Federally Promulgated Water Quality Standards § 131.35 Colville...

  15. High-resolution remote sensing of water quality in the San Francisco Bay-Delta Estuary

    USGS Publications Warehouse

    Fichot, Cédric G.; Downing, Bryan D.; Bergamaschi, Brian; Windham-Myers, Lisamarie; Marvin-DiPasquale, Mark C.; Thompson, David R.; Gierach, Michelle M.

    2015-01-01

    The San Francisco Bay–Delta Estuary watershed is a major source of freshwater for California and a profoundly human-impacted environment. The water quality monitoring that is critical to the management of this important water resource and ecosystem relies primarily on a system of fixed water-quality monitoring stations, but the limited spatial coverage often hinders understanding. Here, we show how the latest technology in visible/near-infrared imaging spectroscopy can facilitate water quality monitoring in this highly dynamic and heterogeneous system by enabling simultaneous depictions of several water quality indicators at very high spatial resolution. The airborne portable remote imaging spectrometer (PRISM) was used to derive high-spatial-resolution (2.6 × 2.6 m) distributions of turbidity, and dissolved organic carbon (DOC) and chlorophyll-a concentrations in a wetland-influenced region of this estuary. A filter-passing methylmercury vs DOC relationship was also developed using in situ samples and enabled the high-spatial-resolution depiction of surface methylmercury concentrations in this area. The results illustrate how high-resolution imaging spectroscopy can inform management and policy development in important inland and estuarine water bodies by facilitating the detection of point- and nonpoint-source pollution, and by providing data to help assess the complex impacts of wetland restoration and climate change on water quality and ecosystem productivity.

  16. Photonic Crystal Microchip Laser.

    PubMed

    Gailevicius, Darius; Koliadenko, Volodymyr; Purlys, Vytautas; Peckus, Martynas; Taranenko, Victor; Staliunas, Kestutis

    2016-09-29

    The microchip lasers, being very compact and efficient sources of coherent light, suffer from one serious drawback: low spatial quality of the beam strongly reducing the brightness of emitted radiation. Attempts to improve the beam quality, such as pump-beam guiding, external feedback, either strongly reduce the emission power, or drastically increase the size and complexity of the lasers. Here it is proposed that specially designed photonic crystal in the cavity of a microchip laser, can significantly improve the beam quality. Experiments show that a microchip laser, due to spatial filtering functionality of intracavity photonic crystal, improves the beam quality factor M 2 reducing it by a factor of 2, and increase the brightness of radiation by a factor of 3. This comprises a new kind of laser, the "photonic crystal microchip laser", a very compact and efficient light source emitting high spatial quality high brightness radiation.

  17. A Spatial and Temporal Assessment of Non-Point Groundwater Pollution Sources, Tutuila Island, American Samoa

    NASA Astrophysics Data System (ADS)

    Shuler, C. K.; El-Kadi, A. I.; Dulaiova, H.; Glenn, C. R.; Fackrell, J.

    2015-12-01

    The quality of municipal groundwater supplies on Tutuila, the main island in American Samoa, is currently in question. A high vulnerability for contamination from surface activities has been recognized, and there exists a strong need to clearly identify anthropogenic sources of pollution and quantify their influence on the aquifer. This study examines spatial relationships and time series measurements of nutrients and other tracers to identify predominant pollution sources and determine the water quality impacts of the island's diverse land uses. Elevated groundwater nitrate concentrations are correlated with areas of human development, however, the mixture of residential and agricultural land use in this unique village based agrarian setting makes specific source identification difficult using traditional geospatial analysis. Spatial variation in anthropogenic impact was assessed by linking NO3- concentrations and δ15N(NO3) from an extensive groundwater survey to land-use types within well capture zones and groundwater flow-paths developed with MODFLOW, a numerical groundwater model. Land use types were obtained from high-resolution GIS data and compared to water quality results with multiple-regression analysis to quantify the impact that different land uses have on water quality. In addition, historical water quality data and new analyses of δD and δ18O in precipitation, groundwater, and mountain-front recharge waters were used to constrain the sources and mechanisms of contamination. Our analyses indicate that groundwater nutrient levels on Tutuila are controlled primarily by residential, not agricultural activity. Also a lack of temporal variation suggests that episodic pollution events are limited to individual water sources as opposed to the entire aquifer. These results are not only valuable for water quality management on Tutuila, but also provide insight into the sustainability of groundwater supplies on other islands with similar hydrogeology and land use history.

  18. First refraction contrast imaging via Laser-Compton Scattering X-ray at KEK

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sakaue, Kazuyuki; Aoki, Tatsuro; Washio, Masakazu

    2012-07-31

    Laser-Compton Scattering (LCS) is one of the most feasible techniques for high quality, high brightness, and compact X-ray source. High energy electron beam produced by accelerators scatters off the laser photon at a small spot. As a laser target, we have been developing a pulsedlaser storage cavity for increasing an X-ray flux. The X-ray flux was still inadequate that was 2.1 Multiplication-Sign 10{sup 5}/sec, however, we performed first refraction contrast imaging in order to evaluate the quality of LCS X-ray. Edge enhanced contrast imaging was achieved by changing the distance from sample to detector. The edge enhancement indicates that themore » LCS X-ray has small source size, i.e. high brightness. We believe that the result has demonstrated good feasibility of linac-based high brightness X-ray sources via laser-electron Compton scatterings.« less

  19. Drinking water sources, availability, quality, access and utilization for goats in the Karak Governorate, Jordan.

    PubMed

    Al-Khaza'leh, Ja'far Mansur; Reiber, Christoph; Al Baqain, Raid; Valle Zárate, Anne

    2015-01-01

    Goat production is an important agricultural activity in Jordan. The country is one of the poorest countries in the world in terms of water scarcity. Provision of sufficient quantity of good quality drinking water is important for goats to maintain feed intake and production. This study aimed to evaluate the seasonal availability and quality of goats' drinking water sources, accessibility, and utilization in different zones in the Karak Governorate in southern Jordan. Data collection methods comprised interviews with purposively selected farmers and quality assessment of water sources. The provision of drinking water was considered as one of the major constraints for goat production, particularly during the dry season (DS). Long travel distances to the water sources, waiting time at watering points, and high fuel and labor costs were the key reasons associated with the problem. All the values of water quality (WQ) parameters were within acceptable limits of the guidelines for livestock drinking WQ with exception of iron, which showed slightly elevated concentration in one borehole source in the DS. These findings show that water shortage is an important problem leading to consequences for goat keepers. To alleviate the water shortage constraint and in view of the depleted groundwater sources, alternative water sources at reasonable distance have to be tapped and monitored for water quality and more efficient use of rainwater harvesting systems in the study area is recommended.

  20. YouTube as a source of chronic obstructive pulmonary disease patient education: a social media content analysis.

    PubMed

    Stellefson, Michael; Chaney, Beth; Ochipa, Kathleen; Chaney, Don; Haider, Zeerak; Hanik, Bruce; Chavarria, Enmanuel; Bernhardt, Jay M

    2014-05-01

    The aim of the present study is to conduct a social media content analysis of chronic obstructive pulmonary disease (COPD) patient education videos on YouTube. A systematic search protocol was used to locate 223 videos. Two independent coders evaluated each video to determine topics covered, media source(s) of posted videos, information quality as measured by HONcode guidelines for posting trustworthy health information on the Internet, and viewer exposure/engagement metrics. Over half the videos (n = 113, 50.7%) included information on medication management, with far fewer videos on smoking cessation (n = 40, 17.9%). Most videos were posted by a health agency or organization (n = 128, 57.4%), and the majority of videos were rated as high quality (n = 154, 69.1%). HONcode adherence differed by media source (Fisher's exact test = 20.52, p = 0.01), however with user-generated content receiving the lowest quality scores. Overall level of user engagement as measured by number of "likes," "favorites," "dislikes," and user comments was low (median range = 0-3, interquartile range = 0-16) across all sources of media. Study findings suggest that COPD education via YouTube has the potential to reach and inform patients; however, existing video content and quality varies significantly. Future interventions should help direct individuals with COPD to engage with high-quality patient education videos on YouTube that are posted by reputable health organizations and qualified medical professionals. Patients should be educated to avoid and/or critically view low-quality videos posted by individual YouTube users who are not health professionals.

  1. YouTube as a source of COPD patient education: A social media content analysis

    PubMed Central

    Stellefson, Michael; Chaney, Beth; Ochipa, Kathleen; Chaney, Don; Haider, Zeerak; Hanik, Bruce; Chavarria, Enmanuel; Bernhardt, Jay M.

    2014-01-01

    Objective Conduct a social media content analysis of COPD patient education videos on YouTube. Methods A systematic search protocol was used to locate 223 videos. Two independent coders evaluated each video to determine topics covered, media source(s) of posted videos, information quality as measured by HONcode guidelines for posting trustworthy health information on the Internet, and viewer exposure/engagement metrics. Results Over half the videos (n=113, 50.7%) included information on medication management, with far fewer videos on smoking cessation (n=40, 17.9%). Most videos were posted by a health agency or organization (n=128, 57.4%), and the majority of videos were rated as high quality (n=154, 69.1%). HONcode adherence differed by media source (Fisher’s Exact Test=20.52, p=.01), with user-generated content (UGC) receiving the lowest quality scores. Overall level of user engagement as measured by number of “likes,” “favorites,” “dislikes,” and user comments was low (mdn range = 0–3, interquartile (IQR) range = 0–16) across all sources of media. Conclusion Study findings suggest that COPD education via YouTube has the potential to reach and inform patients, however, existing video content and quality varies significantly. Future interventions should help direct individuals with COPD to increase their engagement with high-quality patient education videos on YouTube that are posted by reputable health organizations and qualified medical professionals. Patients should be educated to avoid and/or critically view low-quality videos posted by individual YouTube users who are not health professionals. PMID:24659212

  2. Building Portals for Evidence-Informed Education: Lessons from the Dead. A Case Study of the Development of a National Portal Intended to Enhance Evidence Informed Professionalism in Education

    ERIC Educational Resources Information Center

    Blamires, Mike

    2015-01-01

    Access to high-quality evidence has been cited as central to the enhancement of teacher professionalism. This is not a given and teacher access to high-quality evidence requires significant planning and effort. This paper considers the creation of quality-assured reviews to build sustainable quality-assured evidence sources that inform the…

  3. The maladies of water and war: addressing poor water quality in Iraq.

    PubMed

    Zolnikov, Tara Rava

    2013-06-01

    Water is essential in providing nutrients, but contaminated water contributes to poor population health. Water quality and availability can change in unstructured situations, such as war. To develop a practical strategy to address poor water quality resulting from intermittent wars in Iraq, I reviewed information from academic sources regarding waterborne diseases, conflict and war, water quality treatment, and malnutrition. The prevalence of disease was high in impoverished, malnourished populations exposed to contaminated water sources. The data aided in developing a strategy to improve water quality in Iraq, which encompasses remineralized water from desalination plants, health care reform, monitoring and evaluation systems, and educational public health interventions.

  4. [Research on stormwater runoff quality of mountain city by source area monitoring].

    PubMed

    Li, Li-Qing; Shan, Bao-Qing; Zhao, Jian-Wei; Guo, Shu-Gang; Gao, Yong

    2012-10-01

    Stormwater runoff samples were collected from 10 source areas in Mountain City, Chongqing, during five rain events in an attempt to investigate the characteristics of runoff quality and influencing factors. The outcomes are expected to offer practical guidance of sources control of urban runoff pollution. The results indicated that the stormwater runoff of Mountain City presented a strong first flush for almost all events and constituents. The runoff quality indices were also influenced by the rainfall intensity. The concentration of TSS, COD, TN and TP decreased as the rainfall intensity increased. The concentrations of COD and TP in stormwater runoff were highly correlated with TSS concentrations. Suspended solid matter were not only the main pollutant of stormwater runoff but also served as the vehicle for transport of organic matter and phosphorus. Organic matter and phosphorus in stormwatrer runoff were mainly bound to particles, whereas nitrogen was predominantly dissolved, with ammonia and nitrate. A significant difference of stormwater runoff quality was observed among the ten monitored source areas. The highest magnitude of urban stormwater runoff pollution was expected in the commercial area and the first trunk road, followed by the minor road, residential area, parking lot and roof. Urban surface function, traffic volume, population density, and street sweeping practice are the main factors determining spatial differentiation of urban surface runoff quality. Commercial area, the first trunk road and residential area with high population density are the critical sources areas of urban stormwater runoff pollution.

  5. Photonic Crystal Microchip Laser

    NASA Astrophysics Data System (ADS)

    Gailevicius, Darius; Koliadenko, Volodymyr; Purlys, Vytautas; Peckus, Martynas; Taranenko, Victor; Staliunas, Kestutis

    2016-09-01

    The microchip lasers, being very compact and efficient sources of coherent light, suffer from one serious drawback: low spatial quality of the beam strongly reducing the brightness of emitted radiation. Attempts to improve the beam quality, such as pump-beam guiding, external feedback, either strongly reduce the emission power, or drastically increase the size and complexity of the lasers. Here it is proposed that specially designed photonic crystal in the cavity of a microchip laser, can significantly improve the beam quality. Experiments show that a microchip laser, due to spatial filtering functionality of intracavity photonic crystal, improves the beam quality factor M2 reducing it by a factor of 2, and increase the brightness of radiation by a factor of 3. This comprises a new kind of laser, the “photonic crystal microchip laser”, a very compact and efficient light source emitting high spatial quality high brightness radiation.

  6. Photonic Crystal Microchip Laser

    PubMed Central

    Gailevicius, Darius; Koliadenko, Volodymyr; Purlys, Vytautas; Peckus, Martynas; Taranenko, Victor; Staliunas, Kestutis

    2016-01-01

    The microchip lasers, being very compact and efficient sources of coherent light, suffer from one serious drawback: low spatial quality of the beam strongly reducing the brightness of emitted radiation. Attempts to improve the beam quality, such as pump-beam guiding, external feedback, either strongly reduce the emission power, or drastically increase the size and complexity of the lasers. Here it is proposed that specially designed photonic crystal in the cavity of a microchip laser, can significantly improve the beam quality. Experiments show that a microchip laser, due to spatial filtering functionality of intracavity photonic crystal, improves the beam quality factor M2 reducing it by a factor of 2, and increase the brightness of radiation by a factor of 3. This comprises a new kind of laser, the “photonic crystal microchip laser”, a very compact and efficient light source emitting high spatial quality high brightness radiation. PMID:27683066

  7. Does a research article's country of origin affect perception of its quality and relevance? A national trial of US public health researchers.

    PubMed

    Harris, M; Macinko, J; Jimenez, G; Mahfoud, M; Anderson, C

    2015-12-30

    The source of research may influence one's interpretation of it in either negative or positive ways, however, there are no robust experiments to determine how source impacts on one's judgment of the research article. We determine the impact of source on respondents' assessment of the quality and relevance of selected research abstracts. Web-based survey design using four healthcare research abstracts previously published and included in Cochrane Reviews. All Council on the Education of Public Health-accredited Schools and Programmes of Public Health in the USA. 899 core faculty members (full, associate and assistant professors) Each of the four abstracts appeared with a high-income source half of the time, and low-income source half of the time. Participants each reviewed the same four abstracts, but were randomly allocated to receive two abstracts with high-income source, and two abstracts with low-income source, allowing for within-abstract comparison of quality and relevance Within-abstract comparison of participants' rating scores on two measures--strength of the evidence, and likelihood of referral to a peer (1-10 rating scale). OR was calculated using a generalised ordered logit model adjusting for sociodemographic covariates. Participants who received high income country source abstracts were equal in all known characteristics to the participants who received the abstracts with low income country sources. For one of the four abstracts (a randomised, controlled trial of a pharmaceutical intervention), likelihood of referral to a peer was greater if the source was a high income country (OR 1.28, 1.02 to 1.62, p<0.05). All things being equal, in one of the four abstracts, the respondents were influenced by a high-income source in their rating of research abstracts. More research may be needed to explore how the origin of a research article may lead to stereotype activation and application in research evaluation. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  8. Air quality impacted by local pollution sources and beyond - Using a prominent petro-industrial complex as a study case.

    PubMed

    Chen, Sheng-Po; Wang, Chieh-Heng; Lin, Wen-Dian; Tong, Yu-Huei; Chen, Yu-Chun; Chiu, Ching-Jui; Chiang, Hung-Chi; Fan, Chen-Lun; Wang, Jia-Lin; Chang, Julius S

    2018-05-01

    The present study combines high-resolution measurements at various distances from a world-class gigantic petrochemical complex with model simulations to test a method to assess industrial emissions and their effect on local air quality. Due to the complexity in wind conditions which were highly seasonal, the dominant wind flow patterns in the coastal region of interest were classified into three types, namely northeast monsoonal (NEM) flows, southwest monsoonal (SEM) flows and local circulation (LC) based on six years of monitoring data. Sulfur dioxide (SO 2 ) was chosen as an indicative pollutant for prominent industrial emissions. A high-density monitoring network of 12 air-quality stations distributed within a 20-km radius surrounding the petrochemical complex provided hourly measurements of SO 2 and wind parameters. The SO 2 emissions from major industrial sources registered by the monitoring network were then used to validate model simulations and to illustrate the transport of the SO 2 plumes under the three typical wind patterns. It was found that the coupling of observations and modeling was able to successfully explain the transport of the industrial plumes. Although the petrochemical complex was seemingly the only major source to affect local air quality, multiple prominent sources from afar also played a significant role in local air quality. As a result, we found that a more complete and balanced assessment of the local air quality can be achieved only after taking into account the wind characteristics and emission factors of a much larger spatial scale than the initial (20 km by 20 km) study domain. Copyright © 2018 Elsevier Ltd. All rights reserved.

  9. High-pitch dual-source CT angiography without ECG-gating for imaging the whole aorta: intraindividual comparison with standard pitch single-source technique without ECG-gating

    PubMed Central

    Manna, Carmelinda; Silva, Mario; Cobelli, Rocco; Poggesi, Sara; Rossi, Cristina; Sverzellati, Nicola

    2017-01-01

    PURPOSE We aimed to perform intraindividual comparison of computed tomography (CT) parameters, image quality, and radiation exposure between standard CT angiography (CTA) and high-pitch dual source (DS)-CTA, in subjects undergoing serial CTA of thoracoabdominal aorta. METHODS Eighteen subjects with thoracoabdominal CTA by standard technique and high-pitch DS-CTA technique within 6 months of each other were retrieved for intraindividual comparison of image quality in thoracic and abdominal aorta. Quantitative analysis was performed by comparison of mean aortic attenuation, noise, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR). Qualitative analysis was performed by visual assessment of motion artifacts and diagnostic confidence. Radiation exposure was quantified by effective dose. Image quality was apportioned to radiation exposure by means of figure of merit. RESULTS Mean aortic attenuation and noise were higher in high-pitch DS-CTA of thoracoabdominal aorta, whereas SNR and CNR were similar in thoracic aorta and significantly lower in high-pitch DS-CTA of abdominal aorta (P = 0.024 and P = 0.016). High-pitch DS-CTA was significantly better in the first segment of thoracic aorta. Effective dose was reduced by 72% in high-pitch DS-CTA. CONCLUSION High-pitch DS-CTA without electrocardiography-gating is an effective technique for imaging aorta with very low radiation exposure and with significant reduction of motion artifacts in ascending aorta; however, the overall quality of high-pitch DS-CTA in abdominal aorta is lower than standard CTA. PMID:28703104

  10. [The assessment of the quality of water from sources of decentralized water supply of Ekaterinburg and surrounding areas].

    PubMed

    Konshina, Lidia G

    2016-01-01

    The availability of high-quality drinking water is currently the one out of the most acute problems in the Russian Federation. There was performed an analysis of the chemical composition of drinking water from sources of decentralized supply of inhabitants of the city of Yekaterinburg and the surrounding areas. Average values of indices of the water quality in the wells for individual use in the district of the city of Yekaterinburg not go beyond the standards, with the exception of manganese content. In some sources there were revealed elevated values of chromatic level, oxidability, hardness, content of iron, nitrates, barium, dry residue, ammonium nitrogen, silicon. Percentage of sources that do not meet hygienic requirements on a number of indices can reach 21-23%.

  11. Online Health Information Regarding Male Infertility: An Evaluation of Readability, Suitability, and Quality.

    PubMed

    Robins, Stephanie; Barr, Helena J; Idelson, Rachel; Lambert, Sylvie; Zelkowitz, Phyllis

    2016-10-21

    Many men lack knowledge about male infertility, and this may have consequences for their reproductive and general health. Men may prefer to seek health information online, but these sources of information vary in quality. The objective of this study is to determine if online sources of information regarding male infertility are readable, suitable, and of appropriate quality for Internet users in the general population. This study used a cross-sectional design to evaluate online sources resulting from search engine queries. The following categories of websites were considered: (1) Canadian fertility clinics, (2) North American organizations related to fertility, and (3) the first 20 results of Google searches using the terms "male infertility" and "male fertility preservation" set to the search locations worldwide, English Canada, and French Canada. Websites that met inclusion criteria (N=85) were assessed using readability indices, the Suitability Assessment of Materials (SAM), and the DISCERN tool. The associations between website affiliation (government, university/medical, non-profit organization, commercial/corporate, private practice) and Google placement to readability, suitability, and quality were also examined. None of the sampled websites met recommended levels of readability. Across all websites, the mean SAM score for suitability was 45.37% (SD 11.21), or "adequate", while the DISCERN mean score for quality was 43.19 (SD 10.46) or "fair". Websites that placed higher in Google obtained a higher overall score for quality with an r (58) value of -.328 and a P value of .012, but this position was not related to readability or suitability. In addition, 20% of fertility clinic websites did not include fertility information for men. There is a lack of high quality online sources of information on male fertility. Many websites target their information to women, or fail to meet established readability criteria for the general population. Since men may prefer to seek health information online, it is important that health care professionals develop high quality sources of information on male fertility for the general population.

  12. Introducing nonpoint source transferable quotas in nitrogen trading: The effects of transaction costs and uncertainty.

    PubMed

    Zhou, Xiuru; Ye, Weili; Zhang, Bing

    2016-03-01

    Transaction costs and uncertainty are considered to be significant obstacles in the emissions trading market, especially for including nonpoint source in water quality trading. This study develops a nonlinear programming model to simulate how uncertainty and transaction costs affect the performance of point/nonpoint source (PS/NPS) water quality trading in the Lake Tai watershed, China. The results demonstrate that PS/NPS water quality trading is a highly cost-effective instrument for emissions abatement in the Lake Tai watershed, which can save 89.33% on pollution abatement costs compared to trading only between nonpoint sources. However, uncertainty can significantly reduce the cost-effectiveness by reducing trading volume. In addition, transaction costs from bargaining and decision making raise total pollution abatement costs directly and cause the offset system to deviate from the optimal state. While proper investment in monitoring and measuring of nonpoint emissions can decrease uncertainty and save on the total abatement costs. Finally, we show that the dispersed ownership of China's farmland will bring high uncertainty and transaction costs into the PS/NPS offset system, even if the pollution abatement cost is lower than for point sources. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Photonic crystal microchip laser

    NASA Astrophysics Data System (ADS)

    Gailevicius, D.; Koliadenko, V.; Purlys, V.; Peckus, M.; Taranenko, V.; Staliunas, K.

    2017-02-01

    The microchip lasers, being sources of coherent light, suffer from one serious drawback: low spatial quality of the beam, strongly reducing the brightness of emitted radiation. Attempts to improve the beam quality, such as pump-beam guiding, external feedback, either strongly reduce the emission power, or drastically increase the size and complexity of the lasers. Here we propose that specially designed photonic crystal in the cavity of a microchip laser, can significantly improve the beam quality. We experimentally show that a microchip laser, due to spatial filtering functionality of intracavity photonic crystal, improves the beam quality factor M2 reducing it by factor of 2, and thus increase the brightness of radiation by a factor of 4. This comprises a new kind of laser, the "photonic crystal microchip laser", a very compact and efficient light source emitting high spatial high brightness radiation.

  14. Vapor Phase Growth of High-Quality Bi-Te Compounds Using Elemental Bi and Te Sources: A Comparison Between High Vacuum and Atmospheric Pressure

    NASA Astrophysics Data System (ADS)

    Concepción, O.; Escobosa, A.; de Melo, O.

    2018-03-01

    Bismuth telluride (Bi2Te3), traditionally used in the industry as thermoelectric material, has deserved much attention recently due to its properties as a topological insulator, a kind of material that might have relevant applications in spintronics or quantum computing, among other innovative uses. The preparation of high-quality material has become a very important technological task. Here, we compare the preparation of Bi2Te3 by physical vapor transport from the evaporation of elemental Bi and Te sources, under either low pressure or atmospheric pressure. The layers were characterized by different techniques to evaluate its structural properties. As a result, it is concluded that, as a consequence of the different transport regimes, films grown at atmospheric pressure present better crystal quality.

  15. The Maladies of Water and War: Addressing Poor Water Quality in Iraq

    PubMed Central

    2013-01-01

    Water is essential in providing nutrients, but contaminated water contributes to poor population health. Water quality and availability can change in unstructured situations, such as war. To develop a practical strategy to address poor water quality resulting from intermittent wars in Iraq, I reviewed information from academic sources regarding waterborne diseases, conflict and war, water quality treatment, and malnutrition. The prevalence of disease was high in impoverished, malnourished populations exposed to contaminated water sources. The data aided in developing a strategy to improve water quality in Iraq, which encompasses remineralized water from desalination plants, health care reform, monitoring and evaluation systems, and educational public health interventions. PMID:23597360

  16. High adherence is necessary to realize health gains from water quality interventions.

    PubMed

    Brown, Joe; Clasen, Thomas

    2012-01-01

    Safe drinking water is critical for health. Household water treatment (HWT) has been recommended for improving access to potable water where existing sources are unsafe. Reports of low adherence to HWT may limit the usefulness of this approach, however. We constructed a quantitative microbial risk model to predict gains in health attributable to water quality interventions based on a range of assumptions about pre-treatment water quality; treatment effectiveness in reducing bacteria, viruses, and protozoan parasites; adherence to treatment interventions; volume of water consumed per person per day; and other variables. According to mean estimates, greater than 500 DALYs may be averted per 100,000 person-years with increased access to safe water, assuming moderately poor pre-treatment water quality that is a source of risk and high treatment adherence (>90% of water consumed is treated). A decline in adherence from 100% to 90% reduces predicted health gains by up to 96%, with sharpest declines when pre-treatment water quality is of higher risk. Results suggest that high adherence is essential in order to realize potential health gains from HWT.

  17. High Adherence Is Necessary to Realize Health Gains from Water Quality Interventions

    PubMed Central

    Brown, Joe; Clasen, Thomas

    2012-01-01

    Background Safe drinking water is critical for health. Household water treatment (HWT) has been recommended for improving access to potable water where existing sources are unsafe. Reports of low adherence to HWT may limit the usefulness of this approach, however. Methods and Findings We constructed a quantitative microbial risk model to predict gains in health attributable to water quality interventions based on a range of assumptions about pre-treatment water quality; treatment effectiveness in reducing bacteria, viruses, and protozoan parasites; adherence to treatment interventions; volume of water consumed per person per day; and other variables. According to mean estimates, greater than 500 DALYs may be averted per 100,000 person-years with increased access to safe water, assuming moderately poor pre-treatment water quality that is a source of risk and high treatment adherence (>90% of water consumed is treated). A decline in adherence from 100% to 90% reduces predicted health gains by up to 96%, with sharpest declines when pre-treatment water quality is of higher risk. Conclusions Results suggest that high adherence is essential in order to realize potential health gains from HWT. PMID:22586491

  18. Transforming High School Classrooms with Free/Open Source Software: "It's Time for an Open Source Software Revolution"

    ERIC Educational Resources Information Center

    Pfaffman, Jay

    2008-01-01

    Free/Open Source Software (FOSS) applications meet many of the software needs of high school science classrooms. In spite of the availability and quality of FOSS tools, they remain unknown to many teachers and utilized by fewer still. In a world where most software has restrictions on copying and use, FOSS is an anomaly, free to use and to…

  19. Nanoscale imaging with table-top coherent extreme ultraviolet source based on high harmonic generation

    NASA Astrophysics Data System (ADS)

    Ba Dinh, Khuong; Le, Hoang Vu; Hannaford, Peter; Van Dao, Lap

    2017-08-01

    A table-top coherent diffractive imaging experiment on a sample with biological-like characteristics using a focused narrow-bandwidth high harmonic source around 30 nm is performed. An approach involving a beam stop and a new reconstruction algorithm to enhance the quality of reconstructed the image is described.

  20. Evaluating Quality of Aged Archival Formalin-Fixed Paraffin-Embedded Samples for RNA-Sequencing

    EPA Science Inventory

    Archival formalin-fixed paraffin-embedded (FFPE) samples offer a vast, untapped source of genomic data for biomarker discovery. However, the quality of FFPE samples is often highly variable, and conventional methods to assess RNA quality for RNA-sequencing (RNA-seq) are not infor...

  1. Linkages between forest soils and water quality and quantity

    Treesearch

    Daniel G. Neary; George G. Ice; C. Rhett Jackson

    2009-01-01

    The most sustainable and best quality fresh water sources in the world originate in forest ecosystems. The biological, chemical, and physical characteristics of forest soils are particularly well suited to delivering high quality water to streams, moderating stream hydrology, and providing diverse aquatic habitat. Forest soils feature litter layers and...

  2. Water-quality assessment of the Kentucky River basin, Kentucky; results of investigations of surface-water quality, 1987-90

    USGS Publications Warehouse

    Haag, K.H.; Garcia, Rene; Jarrett, G.L.; Porter, S.D.

    1995-01-01

    The U.S. Geological Survey investigated the water quality of the Kentucky River Basin in Kentucky as part of the National Water-Quality Assessment program. Data collected during 1987-90 were used to describe the spatial and temporal variability of water-quality constituents including metals and trace elements, nutrients, sediments, pesticides, dissolved oxygen, and fecal-coliform bacteria. Oil-production activities were the source of barium, bromide, chloride, magnesium, and sodium in several watersheds. High concentrations of aluminum, iron, and zinc were related to surface mining in the Eastern Coal Field Region. High concentrations of lead and zinc occurred in streambed sediments in urban areas, whereas concentrations of arsenic, strontium, and uranium were associated with natural geologic sources. Concentrations of phosphorus were significantly correlated with urban and agricultural land use. The high phosphorus content of Bluegrass Region soils was an important source of phosphorus in streams. At many sites in urban areas, most of the stream nitrogen load was attributable to wastewater-treatment-plant effluent. Average suspended-sediment concentrations were positively correlated with discharge. There was a downward trend in suspended-sediment concentrations downstream in the Kentucky River main stem during the study. The most frequently detected herbicides in water samples were atrazine, 2,4-D, alachlor, metolachlor, and dicamba. Diazinon, malathion, and parathion were the most frequently detected organophosphate insecticides in water samples. Detectable concentrations of aldrin, chlordane, DDT, DDE, dieldrin, endrin, endosulfan, heptachlor, and lindane were found in streambed-sediment samples. Dissolved-oxygen concentrations were sometimes below the minimum concentration needed to sustain aquatic life. At some sites, high concentrations of fecal-indicator bacteria were found and water samples did not meet sanitary water-quality criteria.

  3. Impact of RO-desalted water on distribution water qualities.

    PubMed

    Taylor, J; Dietz, J; Randall, A; Hong, S

    2005-01-01

    A large-scale pilot distribution study was conducted to investigate the impacts of blending different source waters on distribution water qualities, with an emphasis on metal release (i.e. corrosion). The principal source waters investigated were conventionally treated ground water (G1), surface water processed by enhanced treatment (S1), and desalted seawater by reverse osmosis membranes (RO). Due to the nature of raw water quality and associated treatment processes, G1 water had high alkalinity, while S1 and RO sources were characterized as high sulfate and high chloride waters, respectively. The blending ratio of different treated waters determined the quality of finished waters. Iron release from aged cast iron pipes increased significantly when exposed to RO and S1 waters: that is, the greater iron release was experienced with alkalinity reduced below the background of G1 water. Copper release to drinking water, however, increased with increasing alkalinity and decreasing pH. Lead release, on the other hand, increased with increasing chloride and decreasing sulfate. The effect of pH and alkalinity on lead release was not clearly observed from pilot blending study. The flat and compact corrosion scales observed for lead surface exposed to S1 water may be attributable to lead concentration less than that of RO water blends.

  4. SU-G-201-16: Thermal Imaging in Source Visualization and Radioactivity Measurement for High Dose Rate Brachytherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhu, X; Lei, Y; Zheng, D

    2016-06-15

    Purpose: High Dose Rate (HDR) brachytherapy poses a special challenge to radiation safety and quality assurance (QA) due to its high radioactivity, and it is thus critical to verify the HDR source location and its radioactive strength. This study demonstrates a new method for measuring HDR source location and radioactivity utilizing thermal imaging. A potential application would relate to HDR QA and safety improvement. Methods: Heating effects by an HDR source were studied using Finite Element Analysis (FEA). Thermal cameras were used to visualize an HDR source inside a plastic applicator made of polyvinylidene difluoride (PVDF). Using different source dwellmore » times, correlations between the HDR source strength and heating effects were studied, thus establishing potential daily QA criteria using thermal imaging Results: For an Ir1?2 source with a radioactivity of 10 Ci, the decay-induced heating power inside the source is ∼13.3 mW. After the HDR source was extended into the PVDF applicator and reached thermal equilibrium, thermal imaging visualized the temperature gradient of 10 K/cm along the PVDF applicator surface, which agreed with FEA modeling. For Ir{sup 192} source activities ranging from 4.20–10.20 Ci, thermal imaging could verify source activity with an accuracy of 6.3% with a dwell time of 10 sec, and an accuracy of 2.5 % with 100 sec. Conclusion: Thermal imaging is a feasible tool to visualize HDR source dwell positions and verify source integrity. Patient safety and treatment quality will be improved by integrating thermal measurements into HDR QA procedures.« less

  5. ScanRanker: Quality Assessment of Tandem Mass Spectra via Sequence Tagging

    PubMed Central

    Ma, Ze-Qiang; Chambers, Matthew C.; Ham, Amy-Joan L.; Cheek, Kristin L.; Whitwell, Corbin W.; Aerni, Hans-Rudolf; Schilling, Birgit; Miller, Aaron W.; Caprioli, Richard M.; Tabb, David L.

    2011-01-01

    In shotgun proteomics, protein identification by tandem mass spectrometry relies on bioinformatics tools. Despite recent improvements in identification algorithms, a significant number of high quality spectra remain unidentified for various reasons. Here we present ScanRanker, an open-source tool that evaluates the quality of tandem mass spectra via sequence tagging with reliable performance in data from different instruments. The superior performance of ScanRanker enables it not only to find unassigned high quality spectra that evade identification through database search, but also to select spectra for de novo sequencing and cross-linking analysis. In addition, we demonstrate that the distribution of ScanRanker scores predicts the richness of identifiable spectra among multiple LC-MS/MS runs in an experiment, and ScanRanker scores assist the process of peptide assignment validation to increase confident spectrum identifications. The source code and executable versions of ScanRanker are available from http://fenchurch.mc.vanderbilt.edu. PMID:21520941

  6. SU-F-T-32: Evaluation of the Performance of a Multiple-Array-Diode Detector for Quality Assurance Tests in High-Dose-Rate Brachytherapy with Ir-192 Source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harpool, K; De La Fuente Herman, T; Ahmad, S

    Purpose: To evaluate the performance of a two-dimensional (2D) array-diode- detector for geometric and dosimetric quality assurance (QA) tests of high-dose-rate (HDR) brachytherapy with an Ir-192-source. Methods: A phantom setup was designed that encapsulated a two-dimensional (2D) array-diode-detector (MapCheck2) and a catheter for the HDR brachytherapy Ir-192 source. This setup was used to perform both geometric and dosimetric quality assurance for the HDR-Ir192 source. The geometric tests included: (a) measurement of the position of the source and (b) spacing between different dwell positions. The dosimteric tests include: (a) linearity of output with time, (b) end effect and (c) relative dosemore » verification. The 2D-dose distribution measured with MapCheck2 was used to perform the previous tests. The results of MapCheck2 were compared with the corresponding quality assurance testes performed with Gafchromic-film and well-ionization-chamber. Results: The position of the source and the spacing between different dwell-positions were reproducible within 1 mm accuracy by measuring the position of maximal dose using MapCheck2 in contrast to the film which showed a blurred image of the dwell positions due to limited film sensitivity to irradiation. The linearity of the dose with dwell times measured from MapCheck2 was superior to the linearity measured with ionization chamber due to higher signal-to-noise ratio of the diode readings. MapCheck2 provided more accurate measurement of the end effect with uncertainty < 1.5% in comparison with the ionization chamber uncertainty of 3%. Although MapCheck2 did not provide absolute calibration dosimeter for the activity of the source, it provided accurate tool for relative dose verification in HDR-brachytherapy. Conclusion: The 2D-array-diode-detector provides a practical, compact and accurate tool to perform quality assurance for HDR-brachytherapy with an Ir-192 source. The diodes in MapCheck2 have high radiation sensitivity and linearity that is superior to Gafchromic-films and ionization chamber used for geometric and dosimetric QA in HDR-brachytherapy, respectively.« less

  7. YouTube provides irrelevant information for the diagnosis and treatment of hip arthritis.

    PubMed

    Koller, Ulrich; Waldstein, Wenzel; Schatz, Klaus-Dieter; Windhager, Reinhard

    2016-10-01

    YouTube is increasingly becoming a key source for people to satisfy the need for additional information concerning their medical condition. This study analyses the completeness of accurate information found on YouTube pertaining to hip arthritis. The present study analyzed 133 YouTube videos using the search terms: hip arthritis, hip arthritis symptoms, hip arthritis diagnosis, hip arthritis treatment and hip replacement. Two quality assessment checklists with a scale of 0 to 12 points were developed to evaluate available video content for the diagnosis and the treatment of hip arthritis. Videos were grouped into poor quality (grade 0-3), moderate quality (grade 4-7) and excellent quality (grade 8-12), respectively. Three independent observers assessed all videos using the new grading system and independently scored all videos. Discrepancies regarding the categories were clarified by consensus discussion. For intra-observer reliabilities, grading was performed at two occasions separated by four weeks. Eighty-four percent (n = 112) had a poor diagnostic information quality, 14% (n = 19) a moderate quality and only 2% (n = 2) an excellent quality, respectively. In 86% (n = 114), videos provided poor treatment information quality. Eleven percent (n = 15) of videos had a moderate quality and only 3% (n = 4) an excellent quality, respectively. The present study demonstrates that YouTube is a poor source for accurate information pertaining to the diagnosis and treatment of hip arthritis. These finding are of high relevance for clinicians as videos are going to become the primary source of information for patients. Therefore, high quality educational videos are needed to further guide patients on the way from the diagnosis of hip arthritis to its proper treatment.

  8. Consideration of insects as a source of dietary protein for human consumption.

    PubMed

    Churchward-Venne, Tyler A; Pinckaers, Philippe J M; van Loon, Joop J A; van Loon, Luc J C

    2017-12-01

    Consumption of sufficient dietary protein is fundamental to muscle mass maintenance and overall health. Conventional animal-based protein sources such as meat (ie, beef, pork, lamb), poultry, fish, eggs, and dairy are generally considered high-quality sources of dietary protein because they meet all of the indispensable amino-acid requirements for humans and are highly digestible. However, the production of sufficient amounts of conventional animal-based protein to meet future global food demands represents a challenge. Edible insects have recently been proposed as an alternative source of dietary protein that may be produced on a more viable and sustainable commercial scale and, as such, may contribute to ensuring global food security. This review evaluates the protein content, amino-acid composition, and digestibility of edible insects and considers their proposed quality and potential as an alternative protein source for human consumption. © The Author(s) 2017. Published by Oxford University Press on behalf of the International Life Sciences Institute. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  9. An early warning system for groundwater pollution based on the assessment of groundwater pollution risks.

    NASA Astrophysics Data System (ADS)

    Zhang, Weihong.; Zhao, Yongsheng; Hong, Mei; Guo, Xiaodong

    2009-04-01

    Groundwater pollution usually is complex and concealed, remediation of which is difficult, high cost, time-consuming, and ineffective. An early warning system for groundwater pollution is needed that detects groundwater quality problems and gets the information necessary to make sound decisions before massive groundwater quality degradation occurs. Groundwater pollution early warning were performed by considering comprehensively the current groundwater quality, groundwater quality varying trend and groundwater pollution risk . The map of the basic quality of the groundwater was obtained by fuzzy comprehensive evaluation or BP neural network evaluation. Based on multi-annual groundwater monitoring datasets, Water quality state in sometime of the future was forecasted using time-sequenced analyzing methods. Water quality varying trend was analyzed by Spearman's rank correlative coefficient.The relative risk map of groundwater pollution was estimated through a procedure that identifies, cell by cell,the values of three factors, that is inherent vulnerability, load risk of pollution source and contamination hazard. DRASTIC method was used to assess inherent vulnerability of aquifer. Load risk of pollution source was analyzed based on the potential of contamination and pollution degree. Assessment index of load risk of pollution source which involves the variety of pollution source, quantity of contaminants, releasing potential of pollutants, and distance were determined. The load risks of all sources considered by GIS overlay technology. Early warning model of groundwater pollution combined with ComGIS technology organically, the regional groundwater pollution early-warning information system was developed, and applied it into Qiqiha'er groundwater early warning. It can be used to evaluate current water quality, to forecast water quality changing trend, and to analyze space-time influencing range of groundwater quality by natural process and human activities. Keywords: groundwater pollution, early warning, aquifer vulnerability, pollution load, pollution risk, ComGIS

  10. Food source quality and ant dominance hierarchy influence the outcomes of ant-plant interactions in an arid environment

    NASA Astrophysics Data System (ADS)

    Flores-Flores, Rocío Vianey; Aguirre, Armando; Anjos, Diego V.; Neves, Frederico S.; Campos, Ricardo I.; Dáttilo, Wesley

    2018-02-01

    In this study, we conducted a series of experiments in a population of Vachellia constricta (Fabaceae) in the arid Tehuacan-Cuicatláan valley, Mexico, in order to evaluate if the food source quality and ant dominance hierarchy influence the outcomes of ant-plant interactions. Using an experiment with artificial nectaries, we observed that ants foraging on food sources with higher concentration of sugar are quicker in finding and attacking potential herbivorous insects. More specifically, we found that the same ant species may increase their defence effectiveness according to the quality of food available. These findings indicate that ant effectiveness in plant protection is context-dependent and may vary according to specific individual characteristics of plants. In addition, we showed that competitively superior ant species tend to dominate plants in periods with high nectar activity, emphasizing the role of the dominance hierarchy structuring ant-plant interactions. However, when high sugar food sources were experimentally available ad libitum, the nocturnal and competitively superior ant species, Camponotus atriceps, did not dominate the artificial nectaries during the day possibly due to limitation of its thermal tolerance. Therefore, temporal niche partitioning may be allowing the coexistence of two dominant ant species (Camponotus rubritorax during the day and C. atriceps at night) on V. constricta. Our findings indicate that the quality of the food source, and temporal shifts in ant dominance are key factors which structure the biotic plant defences in an arid environment.

  11. Producing high-quality negatives from ERTS black-and-white transparancies

    Treesearch

    Richard J. Myhre

    1973-01-01

    A method has been devised for producing high-quality black-and-white negatives quickly and efficiently from dense transparencies orgininating from Earth Resources Technology Satellite imagery. Transparencies are evaluated on a standard light source to determine exposure and processing information needed for making negatives. A “System ASA Rating” was developed by...

  12. The Prevalence and Quality of Source Attribution in Middle and High School Science Papers

    ERIC Educational Resources Information Center

    Vieyra, Michelle; Weaver, Kari

    2016-01-01

    Plagiarism is a commonly cited problem in higher education, especially in scientific writing and assignments for science courses. Students may not intentionally plagiarize, but may instead be confused about what proper source attribution entails. Much of this confusion likely stems from high school, either from lack of or inconsistent instruction…

  13. High Current Density Cathodes for Future Vacuum Electronics Applications

    DTIC Science & Technology

    2008-05-30

    Tube - device for generating high levels of RF power DARPA Defense Advanced Research Agency PBG Photonic band gap W- Band 75-111 GHz dB Decibels GHz...Extended interaction klystron 1. Introduction All RF vacuum electron sources require a high quality electron beam for efficient operation. Research on...with long life. Pres- ently, only thermionic dispenser cathodes are practical for high power RF sources. Typical thermi- onic cathodes consists of a

  14. Improved ion source

    DOEpatents

    Leung, K.N.; Ehlers, K.W.

    1982-05-04

    A magnetic filter for an ion source reduces the production of undesired ion species and improves the ion beam quality. High-energy ionizing electrons are confined by the magnetic filter to an ion source region, where the high-energy electrons ionize gas molecules. One embodiment of the magnetic filter uses permanent magnets oriented to establish a magnetic field transverse to the direction of travel of ions from the ion source region to the ion extraction region. In another embodiment, low energy 16 eV electrons are injected into the ion source to dissociate gas molecules and undesired ion species into desired ion species,

  15. Ion source

    DOEpatents

    Leung, Ka-Ngo; Ehlers, Kenneth W.

    1984-01-01

    A magnetic filter for an ion source reduces the production of undesired ion species and improves the ion beam quality. High-energy ionizing electrons are confined by the magnetic filter to an ion source region, where the high-energy electrons ionize gas molecules. One embodiment of the magnetic filter uses permanent magnets oriented to establish a magnetic field transverse to the direction of travel of ions from the ion source region to the ion extraction region. In another embodiment, low energy 16 eV electrons are injected into the ion source to dissociate gas molecules and undesired ion species into desired ion species.

  16. Effect of Cultural Distance on Translation of Culture-Bound Texts

    ERIC Educational Resources Information Center

    Rafieyan, Vahid

    2016-01-01

    Sociolinguistic and sociocultural features of the source language can be ideally transferred to the target language when the translator's cultural background knowledge has a high overlap with the source language culture. This signifies the crucial role of national cultural distance from the source language society in the quality of translation of…

  17. Light intensity and quality from sole-source light-emitting diodes impact growth, morphology, and nutrient content of Brassica microgreens

    USDA-ARS?s Scientific Manuscript database

    Multi-layer vertical production systems using sole-source (SS) lighting can be used for microgreen production; however, traditional SS lighting can consume large amounts of electrical energy. Light-emitting diodes (LEDs) offer many advantages over conventional light sources including: high photoelec...

  18. Quality of information sources about mental disorders: a comparison of Wikipedia with centrally controlled web and printed sources.

    PubMed

    Reavley, N J; Mackinnon, A J; Morgan, A J; Alvarez-Jimenez, M; Hetrick, S E; Killackey, E; Nelson, B; Purcell, R; Yap, M B H; Jorm, A F

    2012-08-01

    Although mental health information on the internet is often of poor quality, relatively little is known about the quality of websites, such as Wikipedia, that involve participatory information sharing. The aim of this paper was to explore the quality of user-contributed mental health-related information on Wikipedia and compare this with centrally controlled information sources. Content on 10 mental health-related topics was extracted from 14 frequently accessed websites (including Wikipedia) providing information about depression and schizophrenia, Encyclopaedia Britannica, and a psychiatry textbook. The content was rated by experts according to the following criteria: accuracy, up-to-dateness, breadth of coverage, referencing and readability. Ratings varied significantly between resources according to topic. Across all topics, Wikipedia was the most highly rated in all domains except readability. The quality of information on depression and schizophrenia on Wikipedia is generally as good as, or better than, that provided by centrally controlled websites, Encyclopaedia Britannica and a psychiatry textbook.

  19. Local extinction of dragonfly and damselfly populations in low- and high-quality habitat patches.

    PubMed

    Suhonen, Jukka; Hilli-Lukkarinen, Milla; Korkeamäki, Esa; Kuitunen, Markku; Kullas, Johanna; Penttinen, Jouni; Salmela, Jukka

    2010-08-01

    Understanding the risk of extinction of a single population is an important problem in both theoretical and applied ecology. Local extinction risk depends on several factors, including population size, demographic or environmental stochasticity, natural catastrophe, or the loss of genetic diversity. The probability of local extinction may also be higher in low-quality sink habitats than in high-quality source habitats. We tested this hypothesis by comparing local extinction rates of 15 species of Odonata (dragonflies and damselflies) between 1930-1975 and 1995-2003 in central Finland. Local extinction rates were higher in low-quality than in high-quality habitats. Nevertheless, for the three most common species there were no differences in extinction rates between low- and high-quality habitats. Our results suggest that a good understanding of habitat quality is crucial for the conservation of species in heterogeneous landscapes.

  20. Image Fusion Algorithms Using Human Visual System in Transform Domain

    NASA Astrophysics Data System (ADS)

    Vadhi, Radhika; Swamy Kilari, Veera; Samayamantula, Srinivas Kumar

    2017-08-01

    The endeavor of digital image fusion is to combine the important visual parts from various sources to advance the visibility eminence of the image. The fused image has a more visual quality than any source images. In this paper, the Human Visual System (HVS) weights are used in the transform domain to select appropriate information from various source images and then to attain a fused image. In this process, mainly two steps are involved. First, apply the DWT to the registered source images. Later, identify qualitative sub-bands using HVS weights. Hence, qualitative sub-bands are selected from different sources to form high quality HVS based fused image. The quality of the HVS based fused image is evaluated with general fusion metrics. The results show the superiority among the state-of-the art resolution Transforms (MRT) such as Discrete Wavelet Transform (DWT), Stationary Wavelet Transform (SWT), Contourlet Transform (CT), and Non Sub Sampled Contourlet Transform (NSCT) using maximum selection fusion rule.

  1. Lighting Systems For High Speed Photography Applying Special Metal Halide Discharge Lamps

    NASA Astrophysics Data System (ADS)

    Gillum, Keith M.; Steuernagel, K. H.

    1983-03-01

    High speed photography requires, in addition to a good color quality of the light source, a very high level of illumination. Conventional lighting systems utilizing incandescent lamps or other metal halide lamp types has inherent problems of inefficient light output or poor color quality. Heat generated by incandescent lamps and the power these sources require drive up operating and installation costs. A most economical and practical solution was devised by using the metal halide discharge lamp developed by OSRAM, GmbH of Munich, West Germany. This lamp trade marked the HMITM Metallogen was primarily developed for the needs of the television and motion picture film industry. Due to their high efficiency and other consistent operating qualities these lamps also fulfill the needs of high speed photography, e.g. in crash test facilities, when special engineering activities are carried out. The OSRAM HMITM lamp is an AC discharge metal halide lamp with rare earth additives to increase both the efficiency and light output qualities. Since the lamp is an AC source, a special method had to be developed to overcome the strobing effect, which is normal for AC lamps given their modulated light output, when used with high speed cameras, (e.g. with >1000 fps). This method is based on an increased frequency for the lamp supply voltage coupled with a mix of the light output achieved using a multiphase mains power supply. First developed in 1977, this system using the OSRAM HMITM lamps was installed in a crash test facility of a major automotive manufacturer in West Germany. The design resulted in the best lighting and performance ever experienced. Since that time several other motor companies have made use of this breakthrough. Industrial and scientific users are now considering additional applications use of this advanced high speed lighting system.

  2. High resolution ion chamber array delivery quality assurance for robotic radiosurgery: Commissioning and validation.

    PubMed

    Blanck, Oliver; Masi, Laura; Chan, Mark K H; Adamczyk, Sebastian; Albrecht, Christian; Damme, Marie-Christin; Loutfi-Krauss, Britta; Alraun, Manfred; Fehr, Roman; Ramm, Ulla; Siebert, Frank-Andre; Stelljes, Tenzin Sonam; Poppinga, Daniela; Poppe, Björn

    2016-06-01

    High precision radiosurgery demands comprehensive delivery-quality-assurance techniques. The use of a liquid-filled ion-chamber-array for robotic-radiosurgery delivery-quality-assurance was investigated and validated using several test scenarios and routine patient plans. Preliminary evaluation consisted of beam profile validation and analysis of source-detector-distance and beam-incidence-angle response dependence. The delivery-quality-assurance analysis is performed in four steps: (1) Array-to-plan registration, (2) Evaluation with standard Gamma-Index criteria (local-dose-difference⩽2%, distance-to-agreement⩽2mm, pass-rate⩾90%), (3) Dose profile alignment and dose distribution shift until maximum pass-rate is found, and (4) Final evaluation with 1mm distance-to-agreement criterion. Test scenarios consisted of intended phantom misalignments, dose miscalibrations, and undelivered Monitor Units. Preliminary method validation was performed on 55 clinical plans in five institutions. The 1000SRS profile measurements showed sufficient agreement compared with a microDiamond detector for all collimator sizes. The relative response changes can be up to 2.2% per 10cm source-detector-distance change, but remains within 1% for the clinically relevant source-detector-distance range. Planned and measured dose under different beam-incidence-angles showed deviations below 1% for angles between 0° and 80°. Small-intended errors were detected by 1mm distance-to-agreement criterion while 2mm criteria failed to reveal some of these deviations. All analyzed delivery-quality-assurance clinical patient plans were within our tight tolerance criteria. We demonstrated that a high-resolution liquid-filled ion-chamber-array can be suitable for robotic radiosurgery delivery-quality-assurance and that small errors can be detected with tight distance-to-agreement criterion. Further improvement may come from beam specific correction for incidence angle and source-detector-distance response. Copyright © 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  3. Highly stable ultrabroadband mid-IR optical parametric chirped-pulse amplifier optimized for superfluorescence suppression.

    PubMed

    Moses, J; Huang, S-W; Hong, K-H; Mücke, O D; Falcão-Filho, E L; Benedick, A; Ilday, F O; Dergachev, A; Bolger, J A; Eggleton, B J; Kärtner, F X

    2009-06-01

    We present a 9 GW peak power, three-cycle, 2.2 microm optical parametric chirped-pulse amplification source with 1.5% rms energy and 150 mrad carrier envelope phase fluctuations. These characteristics, in addition to excellent beam, wavefront, and pulse quality, make the source suitable for long-wavelength-driven high-harmonic generation. High stability is achieved by careful optimization of superfluorescence suppression, enabling energy scaling.

  4. Characterising Event-Based DOM Inputs to an Urban Watershed

    NASA Astrophysics Data System (ADS)

    Croghan, D.; Bradley, C.; Hannah, D. M.; Van Loon, A.; Sadler, J. P.

    2017-12-01

    Dissolved Organic Matter (DOM) composition in urban streams is dominated by terrestrial inputs after rainfall events. Urban streams have particularly strong terrestrial-riverine connections due to direct input from terrestrial drainage systems. Event driven DOM inputs can have substantial adverse effects on water quality. Despite this, DOM from important catchment sources such as road drains and Combined Sewage Overflows (CSO's) remains poorly characterised within urban watersheds. We studied DOM sources within an urbanised, headwater watershed in Birmingham, UK. Samples from terrestrial sources (roads, roofs and a CSO), were collected manually after the onset of rainfall events of varying magnitude, and again within 24-hrs of the event ending. Terrestrial samples were analysed for fluorescence, absorbance and Dissolved Organic Carbon (DOC) concentration. Fluorescence and absorbance indices were calculated, and Parallel Factor Analysis (PARAFAC) was undertaken to aid sample characterization. Substantial differences in fluorescence, absorbance, and DOC were observed between source types. PARAFAC-derived components linked to organic pollutants were generally highest within road derived samples, whilst humic-like components tended to be highest within roof samples. Samples taken from the CSO generally contained low fluorescence, however this likely represents a dilution effect. Variation within source groups was particularly high, and local land use seemed to be the driving factor for road and roof drain DOM character and DOC quantity. Furthermore, high variation in fluorescence, absorbance and DOC was apparent between all sources depending on event type. Drier antecedent conditions in particular were linked to greater presence of terrestrially-derived components and higher DOC content. Our study indicates that high variations in DOM character occur between source types, and over small spatial scales. Road drains located on main roads appear to contain the poorest quality DOM of the sources studied due to the presence of hydrocarbons. In order to prevent storm-derived DOM degradation of water quality of urban streams, greater knowledge of links between these drainage sources, and their pathways to streams is required.

  5. High power broadband all fiber super-fluorescent source with linear polarization and near diffraction-limited beam quality.

    PubMed

    Ma, Pengfei; Huang, Long; Wang, Xiaolin; Zhou, Pu; Liu, Zejin

    2016-01-25

    In this manuscript, a high power broadband superfluorescent source (SFS) with linear polarization and near-diffraction-limited beam quality is achieved based on an ytterbium-doped (Yb-doped), all fiberized and polarization-maintained master oscillator power amplifier (MOPA) configuration. The MOPA structure generates a linearly polarized output power of 1427 W with a slope efficiency of 80% and a full width at half maximum (FWHM) of 11 nm, which is power scaled by an order of magnitude compared with the previously reported SFSs with linear polarization. In the experiment, both the polarization extinction ratio (PER) and beam quality (M(2) factor) are degraded little during the power scaling process. At maximal output power, the PER and M(2) factor are measured to be 19.1dB and 1.14, respectively. The root-mean-square (RMS) and peak-vale (PV) values of the power fluctuation at maximal output power are just 0.48% and within 3%, respectively. Further power scaling of the whole system is limited by the available pump sources. To the best of our knowledge, this is the first demonstration of kilowatt level broadband SFS with linear polarization and near-diffraction-limited beam quality.

  6. Development of high definition OCT system for clinical therapy of skin diseases

    NASA Astrophysics Data System (ADS)

    Baek, Daeyul; Seo, Young-Seok; Kim, Jung-Hyun

    2018-02-01

    OCT is a non-invasive imaging technique that can be applied to diagnose various skin disease. Since its introduction in 1997, dermatology has used OCT technology to obtain high quality images of human skin. Recently, in order to accurately diagnose skin diseases, it is essential to develop OCT equipment that can obtain high quality images. Therefore, we developed the system that can obtain a high quality image by using a 1300 nm light source with a wide bandwidth and deep penetration depth, high-resolution image, and a camera capable of high sensitivity and high speed processing. We introduce the performance of the developed system and the clinical application data.

  7. Relations of surface-water quality to streamflow in the Atlantic Coastal, lower Delaware River, and Delaware Bay basins, New Jersey, water years 1976-93

    USGS Publications Warehouse

    Hunchak-Kariouk, Kathryn; Buxton, Debra E.; Hickman, R. Edward

    1999-01-01

    Relations of water quality to streamflow were determined for 18 water-quality constituents at 28 surface-water-quality stations within the drainage area of the Atlantic Coastal, lower Delaware River, and Delaware Bay Basins for water years 1976-93. Surface-water-quality and streamflow data were evaluated for trends (through time) in constituent concentrations during high and low flows, and relations between constituent concentration and streamflow, and between constituent load and streamflow, were determined. Median concentrations were calculated for the entire period of study (water years 1976-93) and for the last 5 years of the period of study (water years 1989-93) to determine whether any large variation in concentration exists between the two periods. Medians also were used to determine the seasonal Kendall\\'s tau statistic, which was then used to evaluate trends in concentrations during high and low flows. Trends in constituent concentrations during high and low flows were evaluated to determine whether the distribution of the observations changes through time for intermittent (nonpoint storm runoff) and constant (point sources and ground water) sources, respectively. High- and low-flow trends in concentrations were determined for some constituents at 26 of the 28 water-quality stations. Seasonal effects on the relations of concentration to streamflow are evident for 10 constituents at 14 or more stations. Dissolved oxygen shows seasonal dependency at all stations. Negative slopes of relations of concentration to streamflow, which indicate a decrease in concentration at high flows, predominate over positive slopes because of dilution of instream concentrations from storm runoff. The slopes of the regression lines of load to streamflow were determined in order to show the relative contributions to the instream load from constant (point sources and ground water) and intermittent sources (storm runoff). Greater slope values indicate larger contributions from storm runoff to instream load, which most likely indicate an increased relative importance of nonpoint sources. Load-to-streamflow relations along a stream reach that tend to increase in a downstream direction indicate the increased relative importance of contributions from storm runoff. Likewise, load-to-streamflow relations along a stream reach that tend to decrease in a downstream direction indicate the increased relative importance of point sources and ground-water discharge. The magnitudes of the load slopes for five constituents increase in the downstream direction along the Great Egg Harbor River, indicating an increased relative importance of storm runoff for these constituents along the river. The magnitudes of the load slopes for 11 constituents decrease in the downstream direction along the Assunpink Creek and for 5 constituents along the Maurice River, indicating a decreased relative importance of storm runoff for these constituents along the rivers.

  8. Online Health Information Regarding Male Infertility: An Evaluation of Readability, Suitability, and Quality

    PubMed Central

    Robins, Stephanie; Barr, Helena J; Idelson, Rachel; Lambert, Sylvie

    2016-01-01

    Background Many men lack knowledge about male infertility, and this may have consequences for their reproductive and general health. Men may prefer to seek health information online, but these sources of information vary in quality. Objective The objective of this study is to determine if online sources of information regarding male infertility are readable, suitable, and of appropriate quality for Internet users in the general population. Methods This study used a cross-sectional design to evaluate online sources resulting from search engine queries. The following categories of websites were considered: (1) Canadian fertility clinics, (2) North American organizations related to fertility, and (3) the first 20 results of Google searches using the terms “male infertility” and “male fertility preservation” set to the search locations worldwide, English Canada, and French Canada. Websites that met inclusion criteria (N=85) were assessed using readability indices, the Suitability Assessment of Materials (SAM), and the DISCERN tool. The associations between website affiliation (government, university/medical, non-profit organization, commercial/corporate, private practice) and Google placement to readability, suitability, and quality were also examined. Results None of the sampled websites met recommended levels of readability. Across all websites, the mean SAM score for suitability was 45.37% (SD 11.21), or “adequate”, while the DISCERN mean score for quality was 43.19 (SD 10.46) or “fair”. Websites that placed higher in Google obtained a higher overall score for quality with an r (58) value of -.328 and a P value of .012, but this position was not related to readability or suitability. In addition, 20% of fertility clinic websites did not include fertility information for men. Conclusions There is a lack of high quality online sources of information on male fertility. Many websites target their information to women, or fail to meet established readability criteria for the general population. Since men may prefer to seek health information online, it is important that health care professionals develop high quality sources of information on male fertility for the general population. PMID:27769954

  9. Field based plastic contamination sensing

    USDA-ARS?s Scientific Manuscript database

    The United States has a long-held reputation of being a dependable source of high quality, contaminant-free cotton. Recently, increased incidence of plastic contamination from sources such as shopping bags, vegetable mulch, surface irrigation tubing, and module covers has threatened the reputation o...

  10. Compact quasi-monoenergetic photon sources from laser-plasma accelerators for nuclear detection and characterization

    NASA Astrophysics Data System (ADS)

    Geddes, Cameron G. R.; Rykovanov, Sergey; Matlis, Nicholas H.; Steinke, Sven; Vay, Jean-Luc; Esarey, Eric H.; Ludewigt, Bernhard; Nakamura, Kei; Quiter, Brian J.; Schroeder, Carl B.; Toth, Csaba; Leemans, Wim P.

    2015-05-01

    Near-monoenergetic photon sources at MeV energies offer improved sensitivity at greatly reduced dose for active interrogation, and new capabilities in treaty verification, nondestructive assay of spent nuclear fuel and emergency response. Thomson (also referred to as Compton) scattering sources are an established method to produce appropriate photon beams. Applications are however restricted by the size of the required high-energy electron linac, scattering (photon production) system, and shielding for disposal of the high energy electron beam. Laser-plasma accelerators (LPAs) produce GeV electron beams in centimeters, using the plasma wave driven by the radiation pressure of an intense laser. Recent LPA experiments are presented which have greatly improved beam quality and efficiency, rendering them appropriate for compact high-quality photon sources based on Thomson scattering. Designs for MeV photon sources utilizing the unique properties of LPAs are presented. It is shown that control of the scattering laser, including plasma guiding, can increase photon production efficiency. This reduces scattering laser size and/or electron beam current requirements to scale compatible with the LPA. Lastly, the plasma structure can decelerate the electron beam after photon production, reducing the size of shielding required for beam disposal. Together, these techniques provide a path to a compact photon source system.

  11. Sources of support and psychological distress among academically successful inner-city youth.

    PubMed

    Kenny, Maureen E; Gallagher, Laura A; Alvarez-Salvat, Rose; Silsby, John

    2002-01-01

    Study 1 examined the relationships between parental attachment, academic achievement, and psychological distress among a multiethnic sample of academically successful inner-city high school students (19 White, 54 Black, 9 Asian, 18 Hispanic). These students participated in an enrichment program designed to prepare high school students for college success. The results suggest that the affective quality of maternal attachment is positively associated with grade point average, and the affective quality of paternal attachment is negatively associated with depressive symptoms. In Study 2, case examples provide an examination of sources of support, life stress, and patterns of resilience. Implications for prevention and intervention are also discussed.

  12. 11 W narrow linewidth laser source at 780nm for laser cooling and manipulation of Rubidium

    NASA Astrophysics Data System (ADS)

    Sané, S. S.; Bennetts, S.; Debs, J. E.; Kuhn, C. C. N.; McDonald, G. D.; Altin, P. A.; Close, J. D.; Robins, N. P.

    2012-04-01

    We present a narrow linewidth continuous laser source with over 11 Watts of output power at 780nm, based on single-pass frequency doubling of an amplified 1560nm fibre laser with 36% efficiency. This source offers a combination of high power, simplicity, mode quality and stability. Without any active stabilization, the linewidth is measured to be below 10kHz. The fibre seed is tunable over 60GHz, which allows access to the D2 transitions in 87Rb and 85Rb, providing a viable high-power source for laser cooling as well as for large-momentum-transfer beamsplitters in atom interferometry. Sources of this type will pave the way for a new generation of high flux, high duty-cycle degenerate quantum gas experiments.

  13. The effect of source credibility on consumers' perceptions of the quality of health information on the Internet.

    PubMed

    Bates, Benjamin R; Romina, Sharon; Ahmed, Rukhsana; Hopson, Danielle

    2006-03-01

    Recent use of the Internet as a source of health information has raised concerns about consumers' ability to tell 'good' information from 'bad' information. Although consumers report that they use source credibility to judge information quality, several observational studies suggest that consumers make little use of source credibility. This study examines consumer evaluations of web pages attributed to a credible source as compared to generic web pages on measures of message quality. In spring 2005, a community-wide convenience survey was distributed in a regional hub city in Ohio, USA. 519 participants were randomly assigned one of six messages discussing lung cancer prevention: three messages each attributed to a highly credible national organization and three identical messages each attributed to a generic web page. Independent sample t-tests were conducted to compare each attributed message to its counterpart attributed to a generic web page on measures of trustworthiness, truthfulness, readability, and completeness. The results demonstrated that differences in attribution to a source did not have a significant effect on consumers' evaluations of the quality of the information.Conclusions. The authors offer suggestions for national organizations to promote credibility to consumers as a heuristic for choosing better online health information through the use of media co-channels to emphasize credibility.

  14. Quality assessment of recent evidence-based clinical practice guidelines for management of type 2 diabetes mellitus in adults using the AGREE II instrument.

    PubMed

    Anwer, Muhammad A; Al-Fahed, Ousama B; Arif, Samir I; Amer, Yasser S; Titi, Maher A; Al-Rukban, Mohammed O

    2018-02-01

    Type 2 diabetes mellitus (T2DM) is a worldwide and national public health problem that has a great impact on the population in Saudi Arabia. High-quality clinical practice guidelines (CPGs) are cornerstones in improving the health care provided for patients with diabetes. This study evaluated the methodological rigour, transparency, and applicability of recently published CPGs. Our group conducted a systematic search for recently published CPGs for T2DM. The searching and screening for Source CPGs were guided by tools from the ADAPTE methods with specific inclusion/exclusion criteria. Five reviewers using the second version of the Appraisal of Guidelines for Research and Evaluation (AGREE II) Instrument independently assessed the quality of the retrieved Source CPGs. Domains of Scope and purpose and Clarity of presentation received the highest scores in all CPGs. Most of the assessed CPGs (86%) were considered with high overall quality and were recommended for use. Rigour of development and applicability domains were together highest in 3 CPGs (43%). The overall high quality of DM CPGs published in the last 3 years demonstrated the continuous development and improvement in CPG methodologies and standards. Health care professionals should consider the quality of any CPG for T2DM before deciding to use it in their daily clinical practice. Three CPGs have been identified, using the AGREE criteria, as high-quality and trustworthy. Ideally, the resources provided by the AGREE trust including the AGREE II Instrument should be used by a clinician to scan through the large number of published T2DM CPGs to identify the CPGs with high methodological quality and applicability. © 2017 John Wiley & Sons, Ltd.

  15. Experimental forest watershed studies contribution to the effect of disturbances on water quality

    Treesearch

    Daniel G. Neary

    2012-01-01

    The most sustainable and best quality fresh water sources in the world originate in forested watersheds (Dissmeyer 2000, Brooks et al. 2003, Barten and Ernst 2004). The biological, chemical, and physical characteristics of forest soils are particularly well suited to delivering high quality water to streams, and moderating the climatic extremes which affect stream...

  16. Negative ion-driven associated particle neutron generator

    DOE PAGES

    Antolak, A. J.; Leung, K. N.; Morse, D. H.; ...

    2015-10-09

    We describe an associated particle neutron generator that employs a negative ion source to produce high neutron flux from a small source size. Furthermore, negative ions produced in an rf-driven plasma source are extracted through a small aperture to form a beam which bombards a positively biased, high voltage target electrode. Electrons co-extracted with the negative ions are removed by a permanent magnet electron filter. The use of negative ions enables high neutron output (100% atomic ion beam), high quality imaging (small neutron source size), and reliable operation (no high voltage breakdowns). Finally, the neutron generator can operate in eithermore » pulsed or continuous-wave (cw) mode and has been demonstrated to produce 10 6 D-D n/s (equivalent to similar to 10 8 D-T n/s) from a 1 mm-diameter neutron source size to facilitate high fidelity associated particle imaging.« less

  17. Microbiological, chemical and physical quality of drinking water for commercial turkeys: a cross-sectional study.

    PubMed

    Di Martino, G; Piccirillo, A; Giacomelli, M; Comin, D; Gallina, A; Capello, K; Buniolo, F; Montesissa, C; Bonfanti, L

    2018-04-17

    Drinking water for poultry is not subject to particular microbiological, chemical and physical requirements, thereby representing a potential transmission route for pathogenic microorganisms and contaminants and/or becoming unsuitable for water-administered medications. This study assessed the microbiological, chemical and physical drinking water quality of 28 turkey farms in North-Eastern Italy: 14 supplied with tap water (TW) and 14 with well water (WW). Water salinity, hardness, pH, ammonia, sulphate, phosphate, nitrate, chromium, copper and iron levels were also assessed. Moreover, total bacterial count at 22°C, presence and enumeration of Enterococcus spp. and E. coli, presence of Salmonella spp. and Campylobacter spp. were quantified. A water sample was collected in winter and in summer at 3 sampling sites: the water source (A), the beginning (B) and the end (C) of the nipple line (168 samples in total). Chemical and physical quality of both TW and WW sources was mostly within the limits of TW for humans. However, high levels of hardness and iron were evidenced in both sources. In WW vs. TW, sulphate and salinity levels were significantly higher, whilst pH and nitrate levels were significantly lower. At site A, microbiological quality of WW and TW was mostly within the limit of TW for humans. However, both sources had a significantly lower microbiological quality at sites B and C. Salmonella enterica subsp. enterica serotype Kentucky was isolated only twice from WW. Campylobacter spp. were rarely isolated (3.6% of farms); however, Campylobacter spp. farm-level prevalence by real-time PCR was up to 43% for both water sources. Winter posed at higher risk than summer for Campylobacter spp. presence in water, whereas no significant associations were found with water source, site, recirculation system, and turkey age. Low salinity and high hardness were significant risk factors for C. coli and C. jejuni presence, respectively. These results show the need of improving sanitization of drinking water pipelines for commercial turkeys.

  18. Water quality in organic systems

    USDA-ARS?s Scientific Manuscript database

    Non-point source contamination is a major water quality concern in the upper Midwestern USA, where plant nutrients, especially NO3-N, are susceptible to leaching due to extensive subsurface draining of the highly productive, but poorly drained, soils found in this region. Environmental impacts assoc...

  19. Systematic review of studies of staffing and quality in nursing homes.

    PubMed

    Bostick, Jane E; Rantz, Marilyn J; Flesner, Marcia K; Riggs, C Jo

    2006-07-01

    To evaluate a range of staffing measures and data sources for long-term use in public reporting of staffing as a quality measure in nursing homes. Eighty-seven research articles and government documents published from 1975 to 2003 were reviewed and summarized. Relevant content was extracted and organized around 3 themes: staffing measures, quality measures, and risk adjustment variables. Data sources for staffing information were also identified. There is a proven association between higher total staffing levels (especially licensed staff) and improved quality of care. Studies also indicate a significant relationship between high turnover and poor resident outcomes. Functional ability, pressure ulcers, and weight loss are the most sensitive quality indicators linked to staffing. The best national data sources for staffing and quality include the Minimum Data Set (MDS) and On-line Survey and Certification Automated Records (OSCAR). However, the accuracy of this self-reported information requires further reliability and validity testing. A nationwide instrument needs to be developed to accurately measure staff turnover. Large-scale studies using payroll data to measure staff retention and its impact on resident outcomes are recommended. Future research should use the most nurse-sensitive quality indicators such as pressure ulcers, functional status, and weight loss.

  20. Mobile Air Quality Monitoring for Local High-Resolution Characterization of Vehicle-Sourced Criteria Pollutant

    DOT National Transportation Integrated Search

    2017-06-19

    Transportation-related emissions are a major source of air pollution in many urban areas. Human exposure to this pollution is related to their proximity to major roadways, yet federal and state Environmental Protection Agencies (EPAs) conduct regulat...

  1. Ion current detector for high pressure ion sources for monitoring separations

    DOEpatents

    Smith, R.D.; Wahl, J.H.; Hofstadler, S.A.

    1996-08-13

    The present invention relates generally to any application involving the monitoring of signal arising from ions produced by electrospray or other high pressure (>100 torr) ion sources. The present invention relates specifically to an apparatus and method for the detection of ions emitted from a capillary electrophoresis (CE) system, liquid chromatography, or other small-scale separation methods. And further, the invention provides a very simple diagnostic as to the quality of the separation and the operation of an electrospray source. 7 figs.

  2. Ion current detector for high pressure ion sources for monitoring separations

    DOEpatents

    Smith, Richard D.; Wahl, Jon H.; Hofstadler, Steven A.

    1996-01-01

    The present invention relates generally to any application involving the monitoring of signal arising from ions produced by electrospray or other high pressure (>100 torr) ion sources. The present invention relates specifically to an apparatus and method for the detection of ions emitted from a capillary electrophoresis (CE) system, liquid chromatography, or other small-scale separation methods. And further, the invention provides a very simple diagnostic as to the quality of the separation and the operation of an electrospray source.

  3. Cortical reinstatement and the confidence and accuracy of source memory.

    PubMed

    Thakral, Preston P; Wang, Tracy H; Rugg, Michael D

    2015-04-01

    Cortical reinstatement refers to the overlap between neural activity elicited during the encoding and the subsequent retrieval of an episode, and is held to reflect retrieved mnemonic content. Previous findings have demonstrated that reinstatement effects reflect the quality of retrieved episodic information as this is operationalized by the accuracy of source memory judgments. The present functional magnetic resonance imaging (fMRI) study investigated whether reinstatement-related activity also co-varies with the confidence of accurate source judgments. Participants studied pictures of objects along with their visual or spoken names. At test, they first discriminated between studied and unstudied pictures and then, for each picture judged as studied, they also judged whether it had been paired with a visual or auditory name, using a three-point confidence scale. Accuracy of source memory judgments- and hence the quality of the source-specifying information--was greater for high than for low confidence judgments. Modality-selective retrieval-related activity (reinstatement effects) also co-varied with the confidence of the corresponding source memory judgment. The findings indicate that the quality of the information supporting accurate judgments of source memory is indexed by the relative magnitude of content-selective, retrieval-related neural activity. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Megahertz ultra-wide-field swept-source retina optical coherence tomography compared to current existing imaging devices.

    PubMed

    Reznicek, Lukas; Klein, Thomas; Wieser, Wolfgang; Kernt, Marcus; Wolf, Armin; Haritoglou, Christos; Kampik, Anselm; Huber, Robert; Neubauer, Aljoscha S

    2014-06-01

    To investigate the image quality of wide-angle cross-sectional and reconstructed fundus images based on ultra-megahertz swept-source Fourier domain mode locking (FDML) OCT compared to current generation diagnostic devices. A 1,050 nm swept-source FDML OCT system was constructed running at 1.68 MHz A-scan rate covering approximately 70° field of view. Twelve normal eyes were imaged with the device applying an isotropically dense sampling protocol (1,900 × 1,900 A-scans) with a fill factor of 100 %. Obtained OCT scan image quality was compared with two commercial OCT systems (Heidelberg Spectralis and Stratus OCT) of the same 12 eyes. Reconstructed en-face fundus images from the same FDML-OCT data set were compared to color fundus, infrared and ultra-wide-field scanning laser images (SLO). Comparison of cross-sectional scans showed a high overall image quality of the 15× averaged FDML images at 1.68 MHz [overall quality grading score: 8.42 ± 0.52, range 0 (bad)-10 (excellent)] comparable to current spectral-domain OCTs (overall quality grading score: 8.83 ± 0.39, p = 0.731). On FDML OCT, a dense 3D data set was obtained covering also the central and mid-peripheral retina. The reconstructed FDML OCT en-face fundus images had high image quality comparable to scanning laser ophthalmoscope (SLO) as judged from retinal structures such as vessels and optic disc. Overall grading score was 8.36 ± 0.51 for FDML OCT vs 8.27 ± 0.65 for SLO (p = 0.717). Ultra-wide-field megahertz 3D FDML OCT at 1.68 MHz is feasible, and provides cross-sectional image quality comparable to current spectral-domain OCT devices. In addition, reconstructed en-face visualization of fundus images result in a wide-field view with high image quality as compared to currently available fundus imaging devices. The improvement of >30× in imaging speed over commercial spectral-domain OCT technology enables high-density scan protocols leading to a data set for high quality cross-sectional and en-face images of the posterior segment.

  5. Reliability and validity assessment of administrative databases in measuring the quality of rectal cancer management.

    PubMed

    Corbellini, Carlo; Andreoni, Bruno; Ansaloni, Luca; Sgroi, Giovanni; Martinotti, Mario; Scandroglio, Ildo; Carzaniga, Pierluigi; Longoni, Mauro; Foschi, Diego; Dionigi, Paolo; Morandi, Eugenio; Agnello, Mauro

    2018-01-01

    Measurement and monitoring of the quality of care using a core set of quality measures are increasing in health service research. Although administrative databases include limited clinical data, they offer an attractive source for quality measurement. The purpose of this study, therefore, was to evaluate the completeness of different administrative data sources compared to a clinical survey in evaluating rectal cancer cases. Between May 2012 and November 2014, a clinical survey was done on 498 Lombardy patients who had rectal cancer and underwent surgical resection. These collected data were compared with the information extracted from administrative sources including Hospital Discharge Dataset, drug database, daycare activity data, fee-exemption database, and regional screening program database. The agreement evaluation was performed using a set of 12 quality indicators. Patient complexity was a difficult indicator to measure for lack of clinical data. Preoperative staging was another suboptimal indicator due to the frequent missing administrative registration of tests performed. The agreement between the 2 data sources regarding chemoradiotherapy treatments was high. Screening detection, minimally invasive techniques, length of stay, and unpreventable readmissions were detected as reliable quality indicators. Postoperative morbidity could be a useful indicator but its agreement was lower, as expected. Healthcare administrative databases are large and real-time collected repositories of data useful in measuring quality in a healthcare system. Our investigation reveals that the reliability of indicators varies between them. Ideally, a combination of data from both sources could be used in order to improve usefulness of less reliable indicators.

  6. Is the National Guideline Clearinghouse a Trustworthy Source of Practice Guidelines for Child and Youth Anxiety and Depression?

    PubMed

    Duda, Stephanie; Fahim, Christine; Szatmari, Peter; Bennett, Kathryn

    2017-07-01

    Innovative strategies that facilitate the use of high quality practice guidelines (PG) are needed. Accordingly, repositories designed to simplify access to PGs have been proposed as a critical component of the network of linked interventions needed to drive increased PG implementation. The National Guideline Clearinghouse (NGC) is a free, international online repository. We investigated whether it is a trustworthy source of child and youth anxiety and depression PGs. English language PGs published between January 2009 and February 2016 relevant to anxiety or depression in children and adolescents (≤ 18 years of age) were eligible. Two trained raters assessed PG quality using Appraisal of Guidelines for Research and Evaluation (AGREE II). Scores on at least three AGREE II domains (stakeholder involvement, rigor of development, and editorial independence) were used to designate PGs as: i) minimum quality (≥ 50%); and ii) high quality (≥ 70%). Eight eligible PGs were identified (depression, n=6; anxiety and depression, n=1; social anxiety disorder, n=1). Four of eight PGs met minimum quality criteria; three of four met high quality criteria. At present, NGC users without the time and special skills required to evaluate PG quality may unknowingly choose flawed PGs to guide decisions about child and youth anxiety and depression. The recent NGC decision to explore the inclusion of PG quality profiles based on Institute of Medicine standards provides needed leadership that can strengthen PG repositories, prevent harm and wasted resources, and build PG developer capacity.

  7. Characterization and source apportionment of health risks from ambient PM10 in Hong Kong over 2000-2011

    NASA Astrophysics Data System (ADS)

    Li, Zhiyuan; Yuan, Zibing; Li, Ying; Lau, Alexis K. H.; Louie, Peter K. K.

    2015-12-01

    Atmospheric particulate matter (PM) pollution is a major public health concern in Hong Kong. In this study, the spatiotemporal variations of health risks from ambient PM10 from seven air quality monitoring stations between 2000 and 2011 were analyzed. Positive matrix factorization (PMF) was adopted to identify major source categories of ambient PM10 and quantify their contributions. Afterwards, a point-estimated risk model was used to identify the inhalation cancer and non-cancer risks of PM10 sources. The long-term trends of the health risks from classified local and non-local sources were explored. Furthermore, the reason for the increase of health risks during high PM10 days was discussed. Results show that vehicle exhaust source was the dominant inhalation cancer risk (ICR) contributor (72%), whereas trace metals and vehicle exhaust sources contributed approximately 27% and 21% of PM10 inhalation non-cancer risk (INCR), respectively. The identified local sources accounted for approximately 80% of the ICR in Hong Kong, while contribution percentages of the non-local and local sources for INCR are comparable. The clear increase of ICR at high PM days was mainly attributed to the increase of contributions from coal combustion/biomass burning and secondary sulfate, while the increase of INCR at high PM days was attributed to the increase of contributions from the sources coal combustion/biomass burning, secondary nitrate, and trace metals. This study highlights the importance of health risk-based source apportionment in air quality management with protecting human health as the ultimate target.

  8. A radiation quality correction factor k for well-type ionization chambers for the measurement of the reference air kerma rate of (60)Co HDR brachytherapy sources.

    PubMed

    Schüller, Andreas; Meier, Markus; Selbach, Hans-Joachim; Ankerhold, Ulrike

    2015-07-01

    The aim of this study was to investigate whether a chamber-type-specific radiation quality correction factor kQ can be determined in order to measure the reference air kerma rate of (60)Co high-dose-rate (HDR) brachytherapy sources with acceptable uncertainty by means of a well-type ionization chamber calibrated for (192)Ir HDR sources. The calibration coefficients of 35 well-type ionization chambers of two different chamber types for radiation fields of (60)Co and (192)Ir HDR brachytherapy sources were determined experimentally. A radiation quality correction factor kQ was determined as the ratio of the calibration coefficients for (60)Co and (192)Ir. The dependence on chamber-to-chamber variations, source-to-source variations, and source strength was investigated. For the PTW Tx33004 (Nucletron source dosimetry system (SDS)) well-type chamber, the type-specific radiation quality correction factor kQ is 1.19. Note that this value is valid for chambers with the serial number, SN ≥ 315 (Nucletron SDS SN ≥ 548) onward only. For the Standard Imaging HDR 1000 Plus well-type chambers, the type-specific correction factor kQ is 1.05. Both kQ values are independent of the source strengths in the complete clinically relevant range. The relative expanded uncertainty (k = 2) of kQ is UkQ = 2.1% for both chamber types. The calibration coefficient of a well-type chamber for radiation fields of (60)Co HDR brachytherapy sources can be calculated from a given calibration coefficient for (192)Ir radiation by using a chamber-type-specific radiation quality correction factor kQ. However, the uncertainty of a (60)Co calibration coefficient calculated via kQ is at least twice as large as that for a direct calibration with a (60)Co source.

  9. TM-30 Guidance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Royer, Michael P.

    Minimum color quality standards are necessary, because the light sources most efficient at producing lumens are impractical for use in architectural lighting due to poor color rendition. Thus, accurate measures of color rendition and accompanying performance criteria are essential for helping technology developers and users balance tradeoffs between energy efficiency and lighting quality. Setting higher color-rendition criteria while maintaining use of CRI (e.g., CRI ≥ 90) may filter out some unacceptable light sources, but also filters out many highly desirable light sources and requires a greater tradeoff with energy efficiency. In contrast, specifying color rendition using TM-30 Rf, Rg, andmore » Rcs,h1 has been shown to be effective for differentiating desirable sources while maintaining flexibility for technology development and energy efficiency.« less

  10. Mapping of fluoride endemic areas and correlation studies of fluoride with other quality parameters of drinking water of Veppanapalli block of Dharmapuri district in Tamil Nadu.

    PubMed

    Karthikeyan, G; Sundarraj, A Shunmuga; Elango, K P

    2003-10-01

    193 drinking water samples from water sources of 27 panchayats of Veppanapalli block of Dharmapuri district of Tamil Nadu were analysed for chemical quality parameters. Based on the fluoride content of the water sources, fluoride maps differentiating regions with high / low fluoride levels were prepared using Isopleth mapping technique. The interdependence among the important chemical quality parameters were assessed using correlation studies. The experimental results of the application of linear and multiple regression equations on the influence of hardness, alkalinity, total dissolved solids and pH on fluoride are discussed.

  11. High resolution x-ray and gamma ray imaging using diffraction lenses with mechanically bent crystals

    DOEpatents

    Smither, Robert K [Hinsdale, IL

    2008-12-23

    A method for high spatial resolution imaging of a plurality of sources of x-ray and gamma-ray radiation is provided. High quality mechanically bent diffracting crystals of 0.1 mm radial width are used for focusing the radiation and directing the radiation to an array of detectors which is used for analyzing their addition to collect data as to the location of the source of radiation. A computer is used for converting the data to an image. The invention also provides for the use of a multi-component high resolution detector array and for narrow source and detector apertures.

  12. Identification of water quality degradation hotspots in developing countries by applying large scale water quality modelling

    NASA Astrophysics Data System (ADS)

    Malsy, Marcus; Reder, Klara; Flörke, Martina

    2014-05-01

    Decreasing water quality is one of the main global issues which poses risks to food security, economy, and public health and is consequently crucial for ensuring environmental sustainability. During the last decades access to clean drinking water increased, but 2.5 billion people still do not have access to basic sanitation, especially in Africa and parts of Asia. In this context not only connection to sewage system is of high importance, but also treatment, as an increasing connection rate will lead to higher loadings and therefore higher pressure on water resources. Furthermore, poor people in developing countries use local surface waters for daily activities, e.g. bathing and washing. It is thus clear that water utilization and water sewerage are indispensable connected. In this study, large scale water quality modelling is used to point out hotspots of water pollution to get an insight on potential environmental impacts, in particular, in regions with a low observation density and data gaps in measured water quality parameters. We applied the global water quality model WorldQual to calculate biological oxygen demand (BOD) loadings from point and diffuse sources, as well as in-stream concentrations. Regional focus in this study is on developing countries i.e. Africa, Asia, and South America, as they are most affected by water pollution. Hereby, model runs were conducted for the year 2010 to draw a picture of recent status of surface waters quality and to figure out hotspots and main causes of pollution. First results show that hotspots mainly occur in highly agglomerated regions where population density is high. Large urban areas are initially loading hotspots and pollution prevention and control become increasingly important as point sources are subject to connection rates and treatment levels. Furthermore, river discharge plays a crucial role due to dilution potential, especially in terms of seasonal variability. Highly varying shares of BOD sources across regions, and across sectors demand for an integrated approach to assess main causes of water quality degradation.

  13. Neogene and Quaternary foraminifera and paleoenvironments of a corehole from Horn Island, Mississippi

    USGS Publications Warehouse

    Gibson, Thomas G.

    1994-01-01

    The only semipermanent surface water available on the Southern High Plains plateau of Texas and New Mexico is contained in saline lakes and in the playa lakes that form in shallow depressions, called playa basins, following heavy rainfall. The playas generally are accepted as the main source of recharge to the underlying High Plains (Ogallala) aquifer of the region, and they constitute the major wildlife habitat on the Southern High Plains. Their use as water sources, holding ponds, and waste-disposal sites by agricultural and industrial operations may potentially lead to ground-water contamination and habitat degradation. Therefore, playa lakes will play an essential role in the collection of surface-water quality and ecological data for the Southern High Plains study unit of the National Water-Quality Assessment program of the U.S. Geological Survey.

  14. Beam shaping in high-power broad-area quantum cascade lasers using optical feedback

    PubMed Central

    Ferré, Simon; Jumpertz, Louise; Carras, Mathieu; Ferreira, Robson; Grillot, Frédéric

    2017-01-01

    Broad-area quantum cascade lasers with high output powers are highly desirable sources for various applications including infrared countermeasures. However, such structures suffer from strongly deteriorated beam quality due to multimode behavior, diffraction of light and self-focusing. Quantum cascade lasers presenting high performances in terms of power and heat-load dissipation are reported and their response to a nonlinear control based on optical feedback is studied. Applying optical feedback enables to efficiently tailor its near-field beam profile. The different cavity modes are sequentially excited by shifting the feedback mirror angle. Further control of the near-field profile is demonstrated using spatial filtering. The impact of an inhomogeneous gain as well as the influence of the cavity width are investigated. Compared to existing technologies, that are complex and costly, beam shaping with optical feedback is a more flexible solution to obtain high-quality mid-infrared sources. PMID:28287175

  15. Beam shaping in high-power broad-area quantum cascade lasers using optical feedback.

    PubMed

    Ferré, Simon; Jumpertz, Louise; Carras, Mathieu; Ferreira, Robson; Grillot, Frédéric

    2017-03-13

    Broad-area quantum cascade lasers with high output powers are highly desirable sources for various applications including infrared countermeasures. However, such structures suffer from strongly deteriorated beam quality due to multimode behavior, diffraction of light and self-focusing. Quantum cascade lasers presenting high performances in terms of power and heat-load dissipation are reported and their response to a nonlinear control based on optical feedback is studied. Applying optical feedback enables to efficiently tailor its near-field beam profile. The different cavity modes are sequentially excited by shifting the feedback mirror angle. Further control of the near-field profile is demonstrated using spatial filtering. The impact of an inhomogeneous gain as well as the influence of the cavity width are investigated. Compared to existing technologies, that are complex and costly, beam shaping with optical feedback is a more flexible solution to obtain high-quality mid-infrared sources.

  16. Dietary protein level and source differentially affect bone metabolism, strength, and intestinal calcium transporter expression during ad libitum and food-restricted conditions in male rats

    USDA-ARS?s Scientific Manuscript database

    High protein diets may attenuate bone loss during energy restriction (ER). The objective of the current study was to determine whether high protein diets suppress bone turnover and improve bone quality in rats during ER and whether dietary protein source affects this relationship. Eighty 12-week o...

  17. [The high-molecular glutenins of the soft winter wheats from European countries and their relationship to the glutenin composition of the ancient and modern wheat varieties of Ukraine].

    PubMed

    Rabinovich, S V; Fedak, G; Lukov, O

    2000-01-01

    The sources of high-quality components of HMW glutenines determining grain quality, as initial material for breeding in the conditions of Ukraine were revealed on the base of analysis of 75 literature sources data about composition of high-molecular weight (HMW) glutenin and pedigrees of 598 European wheats from 12 countries, bred in 1923-1997, including, 449 cultivars from West and 149 East Europe. Origin of these components was observed in varieties of Great Britain, France and Germany from ancient Ukrainian wheat Red Fife and it derivative spring wheats of Canada--Marquis, Garnet, Regent, Saunders, Selkirk and of USA--spring wheat Thatcher and winter wheats--Kanred and Oro--as directly as via cultivars of European countries and Australia; in wheats of East European countries from winter wheats Myronivs'ka 808 and Bezostaya 1 (derivative of Ukrainian cultivars Ukrainka and Krymka) and their descendants; in wheats of Austria and Italy--from the both genetical sources.

  18. Single liquid source plasma-enhanced metalorganic chemical vapor deposition of high-quality YBa2Cu3O(7-x) thin films

    NASA Technical Reports Server (NTRS)

    Zhang, Jiming; Gardiner, Robin A.; Kirlin, Peter S.; Boerstler, Robert W.; Steinbeck, John

    1992-01-01

    High quality YBa2Cu3O(7-x) films were grown in-situ on LaAlO3 (100) by a novel single liquid source plasma-enhanced metalorganic chemical vapor deposition process. The metalorganic complexes M(thd) (sub n), (thd = 2,2,6,6-tetramethyl-3,5-heptanedionate; M = Y, Ba, Cu) were dissolved in an organic solution and injected into a vaporizer immediately upstream of the reactor inlet. The single liquid source technique dramatically simplifies current CVD processing and can significantly improve the process reproducibility. X-ray diffraction measurements indicated that single phase, highly c-axis oriented YBa2Cu3O(7-x) was formed in-situ at substrate temperature 680 C. The as-deposited films exhibited a mirror-like surface, had transition temperature T(sub cO) approximately equal to 89 K, Delta T(sub c) less than 1 K, and Jc (77 K) = 10(exp 6) A/sq cm.

  19. Preparation of High-Quality FeV55N Using Ammonia as a Reductant and Nitrogen Source

    NASA Astrophysics Data System (ADS)

    Wu, Yue-Dong; Zhang, Guo-Hua; Chou, Kuo-Chih

    2018-05-01

    High-quality FeV55N has been prepared by using ammonia as a reductant and nitrogen source. The raw materials comprised ammonium vanadate and Fe2O3, which were first reduced and nitrided by ammonia to prepare FeV55N composite powders of VN and Fe2N. Subsequently, the composite powders were sintered at high temperature to obtain a bulk FeV55N alloy. The final products obtained by this method do not contain elemental Al, Si, or C impurities. Furthermore, the residual oxygen content of the final products can be reduced to 0.56 wt.%. After sintering, it is possible to obtain a FeV55N alloy with a density of up to 5.4 g/cm3.

  20. SPIM-fluid: open source light-sheet based platform for high-throughput imaging

    PubMed Central

    Gualda, Emilio J.; Pereira, Hugo; Vale, Tiago; Estrada, Marta Falcão; Brito, Catarina; Moreno, Nuno

    2015-01-01

    Light sheet fluorescence microscopy has recently emerged as the technique of choice for obtaining high quality 3D images of whole organisms/embryos with low photodamage and fast acquisition rates. Here we present an open source unified implementation based on Arduino and Micromanager, which is capable of operating Light Sheet Microscopes for automatized 3D high-throughput imaging on three-dimensional cell cultures and model organisms like zebrafish, oriented to massive drug screening. PMID:26601007

  1. Extracting DNA from 'jaws': high yield and quality from archived tiger shark (Galeocerdo cuvier) skeletal material.

    PubMed

    Nielsen, E E; Morgan, J A T; Maher, S L; Edson, J; Gauthier, M; Pepperell, J; Holmes, B J; Bennett, M B; Ovenden, J R

    2017-05-01

    Archived specimens are highly valuable sources of DNA for retrospective genetic/genomic analysis. However, often limited effort has been made to evaluate and optimize extraction methods, which may be crucial for downstream applications. Here, we assessed and optimized the usefulness of abundant archived skeletal material from sharks as a source of DNA for temporal genomic studies. Six different methods for DNA extraction, encompassing two different commercial kits and three different protocols, were applied to material, so-called bio-swarf, from contemporary and archived jaws and vertebrae of tiger sharks (Galeocerdo cuvier). Protocols were compared for DNA yield and quality using a qPCR approach. For jaw swarf, all methods provided relatively high DNA yield and quality, while large differences in yield between protocols were observed for vertebrae. Similar results were obtained from samples of white shark (Carcharodon carcharias). Application of the optimized methods to 38 museum and private angler trophy specimens dating back to 1912 yielded sufficient DNA for downstream genomic analysis for 68% of the samples. No clear relationships between age of samples, DNA quality and quantity were observed, likely reflecting different preparation and storage methods for the trophies. Trial sequencing of DNA capture genomic libraries using 20 000 baits revealed that a significant proportion of captured sequences were derived from tiger sharks. This study demonstrates that archived shark jaws and vertebrae are potential high-yield sources of DNA for genomic-scale analysis. It also highlights that even for similar tissue types, a careful evaluation of extraction protocols can vastly improve DNA yield. © 2016 John Wiley & Sons Ltd.

  2. PREFACE: Diagnostics for electrical discharge light sources: pushing the limits Diagnostics for electrical discharge light sources: pushing the limits

    NASA Astrophysics Data System (ADS)

    Zissis, Georges; Haverlag, Marco

    2010-06-01

    Light sources play an indispensable role in the daily life of any human being. Quality of life, health and urban security related to traffic and crime prevention depend on light and on its quality. In fact, every day approximately 30 billion electric light sources operate worldwide. These electric light sources consume almost 19% of worldwide electricity production. Finding new ways to light lamps is a challenge where the stakes are scientific, technological, economic and environmental. The production of more efficient light sources is a sustainable solution for humanity. There are many opportunities for not only enhancing the efficiency and reliability of lighting systems but also for improving the quality of light as seen by the end user. This is possible through intelligent use of new technologies, deep scientific understanding of the operating principles of light sources and knowledge of the varied human requirements for different types of lighting in different settings. A revolution in the domain of light source technology is on the way: high brightness light emitting diodes arriving in the general lighting market, together with organic LEDs (OLEDs), are producing spectacular advances. However, unlike incandescence, electrical discharge lamps are far from disappearing from the market. In addition, new generations of discharge lamps based on molecular radiators are becoming a reality. There are still many scientific and technological challenges to be raised in this direction. Diagnostics are important for understanding the fundamental mechanisms taking place in the discharge plasma. This understanding is an absolute necessity for system optimization leading to more efficient and high quality light sources. The studied medium is rather complex, but new diagnostic techniques coupled to innovative ideas and powerful tools have been developed in recent years. This cluster issue of seven papers illustrates these efforts. The selected papers cover all domains, from high to low pressure and dielectric barrier lamps, from breakdown to acoustic resonance. Especially in the domain of high pressure lamps, J J Curry shows how coherent and incoherent x-ray scattering can be used as an imaging technique adapted to lamps. J Hirsch et al treat the acoustic resonance phenomenon that seriously limits the frequency domain for high pressure lamp operation. M Jinno et al illustrate a method that allows for measuring Xe buffer gas pressure in Hg-free metal halide lamps for automotive applications. In the domain of low pressure lamps, M Gendre et al investigate the breakdown phase by means of optical and electrical diagnostic tools. The similarity rules used a long time ago for simulating plasma behaviour based on invariants are now serving as diagnostic tools, as shown in the paper by D Michael et al. N Dagang et al show how impurities can be detected in Hg-free electrodeless lamps and more particularly in dielectric barrier discharges emitting excimer radiation. The quality of light is illustrated by a final example by R Kozakov et al on how to qualify the light output from the lamp with respect to biological effects on humans.

  3. Growth and characterization of β-Ga2O3 thin films by molecular beam epitaxy for deep-UV photodetectors

    NASA Astrophysics Data System (ADS)

    Ghose, Susmita; Rahman, Shafiqur; Hong, Liang; Rojas-Ramirez, Juan Salvador; Jin, Hanbyul; Park, Kibog; Klie, Robert; Droopad, Ravi

    2017-09-01

    The growth of high quality epitaxial beta-gallium oxide (β-Ga2O3) using a compound source by molecular beam epitaxy has been demonstrated on c-plane sapphire (Al2O3) substrates. The compound source provides oxidized gallium molecules in addition to oxygen when heated from an iridium crucible in a high temperature effusion cell enabling a lower heat of formation for the growth of Ga2O3, resulting in a more efficient growth process. This source also enabled the growth of crystalline β-Ga2O3 without the need for additional oxygen. The influence of the substrate temperatures on the crystal structure and quality, chemical bonding, surface morphology, and optical properties has been systematically evaluated by x-ray diffraction, scanning transmission electron microscopy, x-ray photoelectron spectroscopy, atomic force microscopy, spectroscopic ellipsometry, and UV-vis spectroscopy. Under optimized growth conditions, all films exhibited pure (" separators="|2 ¯01 ) oriented β-Ga2O3 thin films with six-fold rotational symmetry when grown on a sapphire substrate. The thin films demonstrated significant absorption in the deep-ultraviolet (UV) region with an optical bandgap around 5.0 eV and a refractive index of 1.9. A deep-UV photodetector fabricated on the high quality β-Ga2O3 thin film exhibits high resistance and small dark current (4.25 nA) with expected photoresponse for 254 nm UV light irradiation suggesting that the material grown using the compound source is a potential candidate for deep-ultraviolet photodetectors.

  4. Poster — Thur Eve — 40: Automated Quality Assurance for Remote-Afterloading High Dose Rate Brachytherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kim, Anthony; Ravi, Ananth

    2014-08-15

    High dose rate (HDR) remote afterloading brachytherapy involves sending a small, high-activity radioactive source attached to a cable to different positions within a hollow applicator implanted in the patient. It is critical that the source position within the applicator and the dwell time of the source are accurate. Daily quality assurance (QA) tests of the positional and dwell time accuracy are essential to ensure that the accuracy of the remote afterloader is not compromised prior to patient treatment. Our centre has developed an automated, video-based QA system for HDR brachytherapy that is dramatically superior to existing diode or film QAmore » solutions in terms of cost, objectivity, positional accuracy, with additional functionalities such as being able to determine source dwell time and transit time of the source. In our system, a video is taken of the brachytherapy source as it is sent out through a position check ruler, with the source visible through a clear window. Using a proprietary image analysis algorithm, the source position is determined with respect to time as it moves to different positions along the check ruler. The total material cost of the video-based system was under $20, consisting of a commercial webcam and adjustable stand. The accuracy of the position measurement is ±0.2 mm, and the time resolution is 30 msec. Additionally, our system is capable of robustly verifying the source transit time and velocity (a test required by the AAPM and CPQR recommendations), which is currently difficult to perform accurately.« less

  5. Oxytocin, Social Support and Sleep Quality In Low Income Minority Women Living with HIV

    PubMed Central

    Fekete, Erin M.; Seay, Julia; Antoni, Michael H.; Mendez, Armando J.; Fletcher, Mary Ann; Szeto, Angela; Schneiderman, Neil

    2013-01-01

    Sleep disturbances are highly prevalent in women with HIV and few studies examine potential protective factors that may reduce risk for sleep disturbances in this high-risk population. We predicted that HIV-specific social support from various sources (i.e., friends, family, spouses), as well as oxytocin (OT), would explain sleep quality in 71 low income minority women living with HIV. Social support from family members was associated with better sleep quality in women. For women with high OT, support from friends was associated with better sleep quality, while for women with low OT, support from friends was associated with poorer sleep quality. Women with low OT may not effectively interpret and utilize available support resources, which may be associated with sleep disturbances. PMID:23799864

  6. Simple, inexpensive technique for high-quality smartphone fundus photography in human and animal eyes.

    PubMed

    Haddock, Luis J; Kim, David Y; Mukai, Shizuo

    2013-01-01

    Purpose. We describe in detail a relatively simple technique of fundus photography in human and rabbit eyes using a smartphone, an inexpensive app for the smartphone, and instruments that are readily available in an ophthalmic practice. Methods. Fundus images were captured with a smartphone and a 20D lens with or without a Koeppe lens. By using the coaxial light source of the phone, this system works as an indirect ophthalmoscope that creates a digital image of the fundus. The application whose software allows for independent control of focus, exposure, and light intensity during video filming was used. With this app, we recorded high-definition videos of the fundus and subsequently extracted high-quality, still images from the video clip. Results. The described technique of smartphone fundus photography was able to capture excellent high-quality fundus images in both children under anesthesia and in awake adults. Excellent images were acquired with the 20D lens alone in the clinic, and the addition of the Koeppe lens in the operating room resulted in the best quality images. Successful photodocumentation of rabbit fundus was achieved in control and experimental eyes. Conclusion. The currently described system was able to take consistently high-quality fundus photographs in patients and in animals using readily available instruments that are portable with simple power sources. It is relatively simple to master, is relatively inexpensive, and can take advantage of the expanding mobile-telephone networks for telemedicine.

  7. Can Sanitary Surveys Replace Water Quality Testing? Evidence from Kisii, Kenya.

    PubMed

    Misati, Aaron Gichaba; Ogendi, George; Peletz, Rachel; Khush, Ranjiv; Kumpel, Emily

    2017-02-07

    Information about the quality of rural drinking water sources can be used to manage their safety and mitigate risks to health. Sanitary surveys, which are observational checklists to assess hazards present at water sources, are simpler to conduct than microbial tests. We assessed whether sanitary survey results were associated with measured indicator bacteria levels in rural drinking water sources in Kisii Central, Kenya. Overall, thermotolerant coliform (TTC) levels were high: all of the samples from the 20 tested dug wells, almost all (95%) of the samples from the 25 tested springs, and 61% of the samples from the 16 tested rainwater harvesting systems were contaminated with TTC. There were no significant associations between TTC levels and overall sanitary survey scores or their individual components. Contamination by TTC was associated with source type (dug wells and springs were more contaminated than rainwater systems). While sanitary surveys cannot be substituted for microbial water quality results in this context, they could be used to identify potential hazards and contribute to a comprehensive risk management approach.

  8. Nursing Home Price and Quality Responses to Publicly Reported Quality Information

    PubMed Central

    Clement, Jan P; Bazzoli, Gloria J; Zhao, Mei

    2012-01-01

    Objective To assess whether the release of Nursing Home Compare (NHC) data affected self-pay per diem prices and quality of care. Data Sources Primary data sources are the Annual Survey of Wisconsin Nursing Homes for 2001–2003, Online Survey and Certification Reporting System, NHC, and Area Resource File. Study Design We estimated fixed effects models with robust standard errors of per diem self-pay charge and quality before and after NHC. Principal Findings After NHC, low-quality nursing homes raised their prices by a small but significant amount and decreased their use of restraints but did not reduce pressure sores. Mid-level and high-quality nursing homes did not significantly increase self-pay prices after NHC nor consistently change quality. Conclusions Our findings suggest that the release of quality information affected nursing home behavior, especially pricing and quality decisions among low-quality facilities. Policy makers should continue to monitor quality and prices for self-pay residents and scrutinize low-quality homes over time to see whether they are on a pathway to improve quality. In addition, policy makers should not expect public reporting to result in quick fixes to nursing home quality problems. PMID:22092366

  9. Influence of health literacy and trust in online information on food allergy quality of life and self-efficacy.

    PubMed

    Ditzler, Nicholas; Greenhawt, Matthew

    2016-09-01

    Health literacy among caregivers of food allergic individuals (FAIs) is poorly described, as are the information sources sought regarding food allergy. To assess the association among health literacy, trust in online sources of information, and food allergy quality of life (QoL) and self-efficacy. An online survey was administered to caregivers of FAIs assessing health literacy (Newest Vital Sign [NVS] and the eHeals Internet health literacy index), trust in online information (Hargittai Internet credibility index and Annenberg National Health Communication Survey [ANHCS]), QoL (Food Allergy Quality of Life Parental Burden), and self-efficacy (Food Allergy Self-Efficacy Questionnaire [FASEQ]). Among 1562 respondents, 94.6% (NVS) and 61.1% (eHeals) had good health literacy, and 58% had high levels of trust in online information (both indexes). The NVS correlated poorly with the eHeals and Hargittai indexes. Hargittai and eHeals scores were moderately correlated (r = 0.37, P < .001). A high NVS score was significantly associated with reported anaphylaxis and high eHeals and Hargittai scores with advocacy group membership. In unadjusted analyses, FAQL-PB scores were worse with high Hargiatti scores (P = .05) and ANHCS scores (P < .001). The FASEQ scores were better with high ANHCS scores (P = .02) and eHeals scores (P < .001). In an adjusted regression, high trust in online information (both indexes), worsening FASEQ score, blog readership, advocacy group membership, caring for multiple FAIs, and having milk or egg allergy were associated with worse FAQL-PB scores. In this sample, health literacy and trust in online information sources were high, with high trust in online information sources negatively associated with QoL. Advocacy group membership had an independent negative association with QoL. Copyright © 2016 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  10. [Airports and air quality: a critical synthesis of the literature].

    PubMed

    Cattani, Giorgio; Di Menno di Bucchianico, Alessandro; Gaeta, Alessandra; Romani, Daniela; Fontana, Luca; Iavicoli, Ivo

    2014-01-01

    This work reviewed existing literature on airport related activities that could worsen surrounding air quality; its aim is to underline the progress coming from recent-year studies, the knowledge emerging from new approaches, the development of semi-empiric analytical methods as well as the questions still needing to be clarified. To estimate pollution levels, spatial and temporal variability, and the sources relative contributions integrated assessment, using both fixed point measurement and model outputs, are needed. The general picture emerging from the studies was a non-negligible and highly spatially variable (within 2-3 km from the fence line) airport contribution; even if it is often not dominant compared to other concomitant pollution sources. Results were highly airport-specific. Traffic volumes, landscape and meteorology were the key variables that drove the impacts. Results were thus hardly exportable to other contexts. Airport related pollutant sources were found to be characterized by unusual emission patterns (particularly ultrafine particles, black carbon and nitrogen oxides during take-off); high time-resolution measurements allow to depict the rapidly changing take-off effect on air quality that could not be adequately observed otherwise. Few studies used high time resolution data in a successful way as statistical models inputs to estimate the aircraft take-off contribution to the observed average levels. These findings should not be neglected when exposure of people living near airports is to be assessed.

  11. Dietary Intake Contributions of Food and Beverages by Source and Food Security Status in US Adults.

    PubMed

    Spees, Colleen K; Clark, Jill E; Hooker, Neal H; Watowicz, Rosanna P; Taylor, Christopher A

    2017-09-01

    To compare the consumption patterns and diet quality of foods and beverages obtained from various sources by food security status. Cross-sectional analysis of 2011-2012 National Health and Nutrition Examination Survey data. A total of 4,789 adults (aged >19 years) with dietary intake and food security data. The contribution of foods and beverages to energy, nutrients, and diet quality by locations where food was obtained was compared across food security status. Descriptive analysis and logistic regression. Almost all US adults consumed food and beverages obtained from grocery stores, regardless of food security status (about 95%), which accounted for one half to two thirds of total macronutrient intakes. The diet quality of foods from grocery stores was better in highly food-secure adults. Convenience stores are used most by very low food-secure adults; those foods had the poorest diet quality profile. Dietary patterns of marginally food-secure adults more closely resembled sources and intakes of low and very low food-secure adults. Food-insecure adults use food sources differently, resulting in diet quality differences of foods and beverages obtained. Place-based interventions in the food environment may have differential effects by food security status. Copyright © 2017 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  12. Field Observations of Hydrodynamics, Sediment Transport, and Water and Sediment Quality in the Hudson-Raritan Estuary

    NASA Astrophysics Data System (ADS)

    Bruno, M. S.; Glenn, S.; Chant, R.; Rankin, K.; Korfiatis, G.; Dimou, N.; Creed, E.; Fullerton, B.; Pence, A.; Burke, P.; Haldeman, C.; Hires, R.; Hunter, E.

    2002-12-01

    The New York-New Jersey Harbor estuary system is of enormous ecological and economic importance to the region. The presence of toxic chemicals in the water and sediments results in reduced water quality, fisheries restrictions/advisories, and general adverse impacts to the estuarine ecosystem. The Port of New York and New Jersey is central to the economy of the region. However, in recent years, problems associated with the management of contaminated dredged material, including high costs and the lack of suitable disposal/use alternatives, have threatened to impact the volume of shipping in the Harbor. Sources of contaminants include atmospheric deposition, municipal and industrial wastewater treatment facilities, combined sewer and stormwater outfalls, and rainfall-induced runoff (non-point sources). In addition, Harbor sediments can act as a continuing source as they are re-suspended and moved throughout the system by both natural and man-made means. As part of the New Jersey Toxics Reduction Workplan, Stevens Institute of Technology and Rutgers University are conducting hydrodynamic, sediment transport, and water and suspended sediment quality measurements in Newark Bay, the Arthur Kill and the Kill van Kull. The goals of the project include: (1) collection of high resolution (event-driven and long-term) hydrodynamic, sediment transport and water and suspended sediment quality measurements for use in the assessment of the dominant physics of the system and in the development of a combined hydrodynamic-sediment transport-water/sediment quality model for the region. (2) identification of those tributaries to NY-NJ Harbor that are significant sources of the chemicals of concern, and evaluation of the importance of non-point sources and existing contaminated bottom sediments as sources of the chemicals of concern. (3) identification of point discharges that represent significant sources of the chemicals of concern. Observations were obtained over a two-year period, during 21 tributary flow "events", each having an approximate duration of 1 week. The measurement program included 3 fixed mooring stations and 5 shipboard locations. Each mooring consisted of an acoustic Doppler current profiler; a high-resolution pressure sensor; an OBS; a CTD; and a laser-based scatterometer. The ship-board measurements included vertical current profiles using a towed acoustic Doppler current profiler; CTD measurements; OBS measurements; suspended sediment concentration and particle size spectrum using a laser-based scatterometer; and chemical characterization of water and suspended sediment samples. The water and sediment quality measurements were obtained using a specially designed Trace Organics Platform Sampler. This sampler allowed for the measurement of low-level concentrations of PCBs (108 congeners), dioxins/furans, Pesticides, PAHs and metals (Hg, Cd, Pb). Preliminary analysis of the data has improved our understanding of the circulation and sediment transport patterns in this region of the estuary, including the influence of extreme tributary flow events, local winds, and anthropogenic effects such as port structures, vessels, and the navigation channels, and has identified the most highly contaminated reaches of the tributaries.

  13. Using high-throughput literature mining to support read-across predictions of skin sensitization (WC)

    EPA Science Inventory

    Read-across predictions require high quality measured data for source analogues. These data are typically retrieved from structured databases, but biomedical literature data are often untapped because current literature mining approaches are resource intensive. Our high-throughpu...

  14. 589 nm sum-frequency generation laser for the LGS/AO of Subaru Telescope

    NASA Astrophysics Data System (ADS)

    Saito, Yoshihiko; Hayano, Yutaka; Saito, Norihito; Akagawa, Kazuyuki; Takazawa, Akira; Kato, Mayumi; Ito, Meguru; Colley, Stephen; Dinkins, Matthew; Eldred, Michael; Golota, Taras; Guyon, Olivier; Hattori, Masayuki; Oya, Shin; Watanabe, Makoto; Takami, Hideki; Iye, Masanori; Wada, Satoshi

    2006-06-01

    We developed a high power and high beam quality 589 nm coherent light source by sum-frequency generation in order to utilize it as a laser guide star at the Subaru telescope. The sum-frequency generation is a nonlinear frequency conversion in which two mode-locked Nd:YAG lasers oscillating at 1064 and 1319 nm mix in a nonlinear crystal to generate a wave at the sum frequency. We achieved the qualities required for the laser guide star. The power of laser is reached to 4.5 W mixing 15.65 W at 1064 nm and 4.99 W at 1319 nm when the wavelength is adjusted to 589.159 nm. The wavelength is controllable in accuracy of 0.1 pm from 589.060 and 589.170 nm. The stability of the power holds within 1.3% during seven hours operation. The transverse mode of the beam is the TEM 00 and M2 of the beam is smaller than 1.2. We achieved these qualities by the following technical sources; (1) simple construction of the oscillator for high beam quality, (2) synchronization of mode-locked pulses at 1064 and 1319 nm by the control of phase difference between two radio frequencies fed to acousto-optic mode lockers, (3) precise tunability of wavelength and spectral band width, and (4) proper selection of nonlinear optical crystal. We report in this paper how we built up each technical source and how we combined those.

  15. A reliable sewage quality abnormal event monitoring system.

    PubMed

    Li, Tianling; Winnel, Melissa; Lin, Hao; Panther, Jared; Liu, Chang; O'Halloran, Roger; Wang, Kewen; An, Taicheng; Wong, Po Keung; Zhang, Shanqing; Zhao, Huijun

    2017-09-15

    With closing water loop through purified recycled water, wastewater becomes a part of source water, requiring reliable wastewater quality monitoring system (WQMS) to manage wastewater source and mitigate potential health risks. However, the development of reliable WQMS is fatally constrained by severe contamination and biofouling of sensors due to the hostile analytical environment of wastewaters, especially raw sewages, that challenges the limit of existing sensing technologies. In this work, we report a technological solution to enable the development of WQMS for real-time abnormal event detection with high reliability and practicality. A vectored high flow hydrodynamic self-cleaning approach and a dual-sensor self-diagnostic concept are adopted for WQMS to effectively encounter vital sensor failing issues caused by contamination and biofouling and ensure the integrity of sensing data. The performance of the WQMS has been evaluated over a 3-year trial period at different sewage catchment sites across three Australian states. It has demonstrated that the developed WQMS is capable of continuously operating in raw sewage for a prolonged period up to 24 months without maintenance and failure, signifying the high reliability and practicality. The demonstrated WQMS capability to reliably acquire real-time wastewater quality information leaps forward the development of effective wastewater source management system. The reported self-cleaning and self-diagnostic concepts should be applicable to other online water quality monitoring systems, opening a new way to encounter the common reliability and stability issues caused by sensor contamination and biofouling. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Comparison of the Microbial Quality of Lamb and Goat Meat Acquired from Internet and Local Retail Markets.

    PubMed

    Kim, Chyer; Stein, Roslyn A; Pao, Steven

    2015-11-01

    This study was conducted to evaluate the microbial quality of lamb and goat meat sold through local (Virginia) and Internet (U. S.) retail markets. A total of 134 frozen meat products consisting of locally purchased lamb ground (LLG) and lamb chops and Internet-procured lamb ground, goat ground, lamb chops (ILC), goat chops (IGC), lamb stew, and goat stew were tested. Significantly higher levels of aerobic mesophiles, psychrotrophs, and coliforms were found in the meat locally acquired than in the meat procured from the Internet. Similar average prevalence (27%) of Escherichia coli was observed regardless of market source. Ground meat had significantly high levels and prevalence of mesophiles, psychrotrophs, coliforms, and Listeria spp. One sample of LLG contained Campylobacter, and one sample of IGC contained Salmonella. Listeria spp. were present in 23 to 40% and 17 to 80% of samples from local and Internet markets, respectively. Pulsed-field gel electrophoresis (PFGE) of isolated E. coli strains revealed brand specificity and genomic diversity. No isolate from different brands and market sources had matching PFGE profiles. The average price of Internet meat ($23.4/kg) was about 1.2 times higher than the price of local meat, except for ILC, whose price was 2.7 times higher. This study revealed differences in microbial quality of lamb and goat meat based on market source; thus, meat products should be handled carefully regardless of market source because of the presence of high microbial levels and the high prevalence of pathogens.

  17. Evaluation of isolation methods for bacterial RNA quantitation in Dickeya dadantii

    USDA-ARS?s Scientific Manuscript database

    Dickeya dadantii is a difficult source for RNA of a sufficient quality for real-time qRT-PCR analysis of gene expression. Three RNA isolation methods were evaluated for their ability to produce high-quality RNA from this bacterium. Bacterial lysis with Trizol using standard protocols consistently ga...

  18. The front end test stand high performance H- ion source at Rutherford Appleton Laboratory.

    PubMed

    Faircloth, D C; Lawrie, S; Letchford, A P; Gabor, C; Wise, P; Whitehead, M; Wood, T; Westall, M; Findlay, D; Perkins, M; Savage, P J; Lee, D A; Pozimski, J K

    2010-02-01

    The aim of the front end test stand (FETS) project is to demonstrate that chopped low energy beams of high quality can be produced. FETS consists of a 60 mA Penning Surface Plasma Ion Source, a three solenoid low energy beam transport, a 3 MeV radio frequency quadrupole, a chopper, and a comprehensive suite of diagnostics. This paper details the design and initial performance of the ion source and the laser profile measurement system. Beam current, profile, and emittance measurements are shown for different operating conditions.

  19. Numerical Simulation of Pollutants' Transport and Fate in AN Unsteady Flow in Lower Bear River, Box Elder County, Utah

    NASA Astrophysics Data System (ADS)

    Salha, A. A.; Stevens, D. K.

    2013-12-01

    This study presents numerical application and statistical development of Stream Water Quality Modeling (SWQM) as a tool to investigate, manage, and research the transport and fate of water pollutants in Lower Bear River, Box elder County, Utah. The concerned segment under study is the Bear River starting from Cutler Dam to its confluence with the Malad River (Subbasin HUC 16010204). Water quality problems arise primarily from high phosphorus and total suspended sediment concentrations that were caused by five permitted point source discharges and complex network of canals and ducts of varying sizes and carrying capacities that transport water (for farming and agriculture uses) from Bear River and then back to it. Utah Department of Environmental Quality (DEQ) has designated the entire reach of the Bear River between Cutler Reservoir and Great Salt Lake as impaired. Stream water quality modeling (SWQM) requires specification of an appropriate model structure and process formulation according to nature of study area and purpose of investigation. The current model is i) one dimensional (1D), ii) numerical, iii) unsteady, iv) mechanistic, v) dynamic, and vi) spatial (distributed). The basic principle during the study is using mass balance equations and numerical methods (Fickian advection-dispersion approach) for solving the related partial differential equations. Model error decreases and sensitivity increases as a model becomes more complex, as such: i) uncertainty (in parameters, data input and model structure), and ii) model complexity, will be under investigation. Watershed data (water quality parameters together with stream flow, seasonal variations, surrounding landscape, stream temperature, and points/nonpoint sources) were obtained majorly using the HydroDesktop which is a free and open source GIS enabled desktop application to find, download, visualize, and analyze time series of water and climate data registered with the CUAHSI Hydrologic Information System. Processing, assessment of validity, and distribution of time-series data was explored using the GNU R language (statistical computing and graphics environment). Physical, chemical, and biological processes equations were written in FORTRAN codes (High Performance Fortran) in order to compute and solve their hyperbolic and parabolic complexities. Post analysis of results conducted using GNU R language. High performance computing (HPC) will be introduced to expedite solving complex computational processes using parallel programming. It is expected that the model will assess nonpoint sources and specific point sources data to understand pollutants' causes, transfer, dispersion, and concentration in different locations of Bear River. Investigation the impact of reduction/removal in non-point nutrient loading to Bear River water quality management could be addressed. Keywords: computer modeling; numerical solutions; sensitivity analysis; uncertainty analysis; ecosystem processes; high Performance computing; water quality.

  20. Citizen-volunteer and professional monitoring to identify fecal sources of contamination in southwestern Puerto Rico

    EPA Science Inventory

    High concentrations of nutrients, fecal microorganisms, and sediments in surface waters can be a public health threat and can impact fringing coral reefs in Guánica Bay in southwestern Puerto Rico. Yet, the main factors and sources contributing to water quality degradation...

  1. Treatments for Neurodevelopmental Disorders: Evidence, Advocacy, and the Internet

    ERIC Educational Resources Information Center

    Di Pietro, Nina C.; Whiteley, Louise; Mizgalewicz, Ania; Illes, Judy

    2013-01-01

    The Internet is a major source of health-related information for parents of sick children despite concerns surrounding quality. For neurodevelopmental disorders, the websites of advocacy groups are a largely unexamined source of information. We evaluated treatment information posted on nine highly-trafficked advocacy websites for autism, cerebral…

  2. Update to the Propagation and Establishment of Aquatic Plants Handbook

    DTIC Science & Technology

    2005-03-01

    decades or even longer. In the interim these reservoirs provide relatively poor aquatic habitat and water quality. Unvegetated aquatic ecosystems are also...establishment or reestab- lishment of aquatic plant communities. Many reservoirs without aquatic plants suffer from poor water quality (high nutrients...serve as a food source for waterfowl and other aquatic wildlife, improve water clarity and quality (James and Barko 1990), reduce rates of

  3. Evaluation of emission control strategies to reduce ozone pollution in the Paso del Norte region using a photochemical air quality modeling system

    NASA Astrophysics Data System (ADS)

    Valenzuela, Victor Hugo

    Air pollution emissions control strategies to reduce ozone precursor pollutants are analyzed by applying a photochemical modeling system. Simulations of air quality conditions during an ozone episode which occurred in June, 2006 are undertaken by increasing or reducing area source emissions in Ciudad Juarez, Chihuahua, Mexico. Two air pollutants are primary drivers in the formation of tropospheric ozone. Oxides of nitrogen (NOx) and volatile organic compounds (VOC) undergo multiple chemical reactions under favorable meteorological conditions to form ozone, which is a secondary pollutant that irritates respiratory systems in sensitive individuals especially the elderly and young children. The U.S. Environmental Protection Agency established National Ambient Air Quality Standards (NAAQS) to limit ambient air pollutants such as ozone by establishing an 8-hour average concentration of 0.075 ppm as the threshold at which a violation of the standard occurs. Ozone forms primarily due reactions in the troposphere of NOx and VOC emissions generated primarily by anthropogenic sources in urban regions. Data from emissions inventories indicate area sources account for ˜15 of NOx and ˜45% of regional VOC emissions. Area sources include gasoline stations, automotive paint bodyshops and nonroad mobile sources. Multiplicity of air pollution emissions sources provides an opportunity to investigate and potentially implement air quality improvement strategies to reduce emissions which contribute to elevated ozone concentrations. A baseline modeling scenario was established using the CAMx photochemical air quality model from which a series of sensitivity analyses for evaluating air quality control strategies were conducted. Modifications to area source emissions were made by varying NOx and / or VOC emissions in the areas of particular interest. Model performance was assessed for each sensitivity analysis. Normalized bias (NB) and normalized error (NE) were used to identify variability of the PREDICTED to OBSERVED ozone concentrations of both BASELINE model and simulations with modified emissions assessed by the sensitivity analysis. All simulations were found to vary within acceptable ranges of these two criteria variables. Simulation results indicate ozone formation in the PdN region is VOC-limited. Under VOC-limited conditions, modifications to NOx emissions do not produce a marked increase or decrease in ozone concentrations. Modifications to VOC emissions generated the highest variability in ozone concentrations. Increasing VOC emissions by 75% produced results which minimized model bias and error when comparing PREDICTED and OBSERVED ozone concentrations. Increasing VOC emissions by 75% either alone or in combination with a 75% increase in NOx emissions generated PREDICTED ozone concentrations very near to OBSERVED ozone. By evaluating the changes in ambient ozone concentrations through photochemical modeling, air quality planners may identify the most efficient or effective VOC emissions control strategies for area sources. Among the strategies to achieve emissions reductions are installation of gasoline vapor recovery systems, replacing high-pressure low-volume surface coating paint spray guns with high-volume low-pressure spray paint guns, requiring emissions control booths for surface coating operations as well as undertaking solvent management practices, requiring the sale of low VOC paint solvents in the surface-coating industry, and requiring low-VOC solvents in the dry cleaning industry. Other strategies to reduce VOC emissions include initiating Eco-Driving strategies to reduce fuel consumption from mobile sources and minimize vehicle idling at the international ports of entry by reducing bridge wait times. This dissertation depicts a tool for evaluating impacts of emissions on regional air quality by addressing the highly unresolved fugitive emissions in the Paso del Norte region. It provides a protocol for decision makers to assess the effects of various emission control strategies in the region. Impacts of specific source categories such as the international ports of entry, gasoline stations, paint body shops, truck stops, and military installations on the regional air quality can be easily and systematically addressed in a timely manner in the future.

  4. Source partitioning of anthropogenic groundwater nitrogen in a mixed-use landscape, Tutuila, American Samoa

    NASA Astrophysics Data System (ADS)

    Shuler, Christopher K.; El-Kadi, Aly I.; Dulai, Henrietta; Glenn, Craig R.; Fackrell, Joseph

    2017-12-01

    This study presents a modeling framework for quantifying human impacts and for partitioning the sources of contamination related to water quality in the mixed-use landscape of a small tropical volcanic island. On Tutuila, the main island of American Samoa, production wells in the most populated region (the Tafuna-Leone Plain) produce most of the island's drinking water. However, much of this water has been deemed unsafe to drink since 2009. Tutuila has three predominant anthropogenic non-point-groundwater-pollution sources of concern: on-site disposal systems (OSDS), agricultural chemicals, and pig manure. These sources are broadly distributed throughout the landscape and are located near many drinking-water wells. Water quality analyses show a link between elevated levels of total dissolved groundwater nitrogen (TN) and areas with high non-point-source pollution density, suggesting that TN can be used as a tracer of groundwater contamination from these sources. The modeling framework used in this study integrates land-use information, hydrological data, and water quality analyses with nitrogen loading and transport models. The approach utilizes a numerical groundwater flow model, a nitrogen-loading model, and a multi-species contaminant transport model. Nitrogen from each source is modeled as an independent component in order to trace the impact from individual land-use activities. Model results are calibrated and validated with dissolved groundwater TN concentrations and inorganic δ15N values, respectively. Results indicate that OSDS contribute significantly more TN to Tutuila's aquifers than other sources, and thus should be prioritized in future water-quality management efforts.

  5. Seismic Source Scaling and Discrimination in Diverse Tectonic Environments

    DTIC Science & Technology

    2009-09-30

    3349-3352. Imanishi, K., W. L. Ellsworth, and S. G. Prejean (2004). Earthquake source parameters determined by the SAFOD Pilot Hole seismic array ... seismic discrimination by performing a thorough investigation of* earthquake source scaling using diverse, high-quality datascts from varied tectonic...these corrections has a direct impact on our ability to identify clandestine explosions in the broad regional areas characterized by low seismicity

  6. "Know Your Well" A Groundwater Quality Project to Inform Students and Well-Owners

    NASA Astrophysics Data System (ADS)

    Olson, C.; Snow, D.; Samal, A.; Ray, C.; Kreifels, M.

    2017-12-01

    Over 15 million U.S. households rely on private, household wells for drinking water, and these sources are not protected under the Safe Drinking Water Act. Data on private well water quality is slowly being collected and evaluated from a number of different agencies, sources and projects. A new project is designed both for training high school students and to help assess the quality of water from rural domestic wells in Nebraska. This "crowd sourced" program engaging high school agricultural education programs, FFA chapters, and science classes with students sampling and testing water sampling from rural domestic wells from 12 districts across the state. Students and teachers from selected school were trained through multiple school visits, both in the classroom and in the field. Classroom visits were used to introduce topics such as water quality and groundwater, and testing methods for specific analytes. During the field visit, students were exposed to field techniques, the importance of accuracy in data collection, and what factors might influence the water in sampled wells. High school students learn to sample and test water independently. Leadership and initiative is developed through the program, and many experience the enlightenment that comes with citizen science. A customized mobile app was developed for ease of data entry and visualization, and data uploaded to a secure website where information was stored and compared to laboratory tests of the same measurements. General water quality parameters, including pH, electrical conductivity, major anions are tested in the field and laboratory, as well as environmental contaminants such as arsenic, uranium, pesticides, bacteria. Test kits provided to each class were used by the students to measure selected parameters, and then duplicate water samples were analyzed at a university laboratory. Five high schools are involved in the project during its first year. Nitrate, bacteria and pesticides represent major concerns for private well owners across the U.S. and preliminary results indicate that nitrate concentrations can range up to 70 mg/L, while detections of bacteria and traces of pesticide residues are consistent with other studies. This project will help both high school students and private well owner become better-informed about water quality in Nebraska.

  7. About to Graduate from High School? Consider Career Education Opportunities. EdSource Student/Parent Guide = Estas por graduarte de la escuela preparatoria? Considera oportunidades para seguir tu educacion de carrera. EdSource guia de estudiantes y padres

    ERIC Educational Resources Information Center

    EdSource, 2006

    2006-01-01

    Getting a sound education is important to a student's ability to make a good living in a field they will enjoy. For many students graduating from high school, that includes high quality career technical (or vocational) education tailored to a specific job. In California, such programs are available in a wide range of fields, from healthcare to the…

  8. Impact of a Usual Source of Care on Health Care Use, Spending, and Quality Among Adults With Mental Health Conditions.

    PubMed

    Fullerton, Catherine A; Witt, Whitney P; Chow, Clifton M; Gokhale, Manjusha; Walsh, Christine E; Crable, Erika L; Naeger, Sarah

    2018-05-01

    Physical comorbidities associated with mental health conditions contribute to high health care costs. This study examined the impact of having a usual source of care (USC) for physical health on health care utilization, spending, and quality for adults with a mental health condition using Medicaid administrative data. Having a USC decreased the probability of inpatient admissions and readmissions. It decreased expenditures on emergency department visits for physical health, 30-day readmissions, and behavioral health inpatient admissions. It also had a positive effect on several quality measures. Results underscore the importance of a USC for physical health and integrated care for adults with mental health conditions.

  9. Does clinical pretest probability influence image quality and diagnostic accuracy in dual-source coronary CT angiography?

    PubMed

    Thomas, Christoph; Brodoefel, Harald; Tsiflikas, Ilias; Bruckner, Friederike; Reimann, Anja; Ketelsen, Dominik; Drosch, Tanja; Claussen, Claus D; Kopp, Andreas; Heuschmid, Martin; Burgstahler, Christof

    2010-02-01

    To prospectively evaluate the influence of the clinical pretest probability assessed by the Morise score onto image quality and diagnostic accuracy in coronary dual-source computed tomography angiography (DSCTA). In 61 patients, DSCTA and invasive coronary angiography were performed. Subjective image quality and accuracy for stenosis detection (>50%) of DSCTA with invasive coronary angiography as gold standard were evaluated. The influence of pretest probability onto image quality and accuracy was assessed by logistic regression and chi-square testing. Correlations of image quality and accuracy with the Morise score were determined using linear regression. Thirty-eight patients were categorized into the high, 21 into the intermediate, and 2 into the low probability group. Accuracies for the detection of significant stenoses were 0.94, 0.97, and 1.00, respectively. Logistic regressions and chi-square tests showed statistically significant correlations between Morise score and image quality (P < .0001 and P < .001) and accuracy (P = .0049 and P = .027). Linear regression revealed a cutoff Morise score for a good image quality of 16 and a cutoff for a barely diagnostic image quality beyond the upper Morise scale. Pretest probability is a weak predictor of image quality and diagnostic accuracy in coronary DSCTA. A sufficient image quality for diagnostic images can be reached with all pretest probabilities. Therefore, coronary DSCTA might be suitable also for patients with a high pretest probability. Copyright 2010 AUR. Published by Elsevier Inc. All rights reserved.

  10. Evaluation of the structural, physicochemical, and biological characteristics of SB4, a biosimilar of etanercept

    PubMed Central

    Cho, Ick Hyun; Lee, Nayoung; Song, Dami; Jung, Seong Young; Bou-Assaf, George; Sosic, Zoran; Zhang, Wei; Lyubarskaya, Yelena

    2016-01-01

    ABSTRACT A biosimilar is a biological medicinal product that is comparable to a reference medicinal product in terms of quality, safety, and efficacy. SB4 was developed as a biosimilar to Enbrel® (etanercept) and was approved as Benepali®, the first biosimilar of etanercept licensed in the European Union (EU). The quality assessment of SB4 was performed in accordance with the ICH comparability guideline and the biosimilar guidelines of the European Medicines Agency and Food and Drug Administration. Extensive structural, physicochemical, and biological testing was performed with state-of-the-art technologies during a side-by-side comparison of the products. Similarity of critical quality attributes (CQAs) was evaluated on the basis of tolerance intervals established from quality data obtained from more than 60 lots of EU-sourced and US-sourced etanercept. Additional quality assessment was focused on a detailed investigation of immunogenicity-related quality attributes, including hydrophobic variants, high-molecular-weight (HMW) species, N-glycolylneuraminic acid (NGNA), and α-1,3-galactose. This comprehensive characterization study demonstrated that SB4 is highly similar to the reference product, Enbrel®, in structural, physicochemical, and biological quality attributes. In addition, the levels of potential immunogenicity-related quality attributes of SB4 such as hydrophobic variants, HMW aggregates, and α-1,3-galactose were less than those of the reference product. PMID:27246928

  11. Evaluating the quality of Internet information for femoroacetabular impingement.

    PubMed

    Lee, Simon; Shin, Jason J; Haro, Marc S; Song, Sang H; Nho, Shane J

    2014-10-01

    The Internet has become a ubiquitous source of medical information for both the patient and the physician. However, the quality of this information is highly variable. We evaluated the quality of Internet information available for femoroacetabular impingement (FAI). Four popular search engines were used to collect 100 Web sites containing information on FAI. Web sites were evaluated based on authorship, various content criteria, and the presence of Health On the Net Code of Conduct (HONcode) certification. By use of a novel evaluation system for quality, Web sites were also classified as excellent, high, moderate, poor, or inadequate and were subsequently analyzed. Web sites were evaluated as a group, followed by authorship type, by HONcode certification, and by quality level. Of the Web sites, 73 offered the ability to contact the author, 91 offered a considerable explanation of FAI, 54 provided surgical treatment options, 58 offered nonsurgical treatment options, 27 discussed possible complications, 11 discussed eligibility criteria, 31 discussed rehabilitation, 67 discussed a differential diagnosis, and 48 included peer-reviewed citations. We categorized 40 Web sites as academic, 33 as private, 9 as industry, 9 as public education, and 9 as blogs. Our novel quality evaluation system classified 16 Web sites as excellent, 18 as high, 17 as moderate, 18 as poor, and 31 as inadequate. Only 8% of all evaluated Web sites contained HONcode certification. We found that the quality of information available on the Internet about FAI was dramatically variable. A significantly large proportion of Web sites were from academic sources, but this did not necessarily indicate higher quality. Sites with HONcode certification showed as much variability in quality as noncertified sites. This study increases clinician competence in the available Internet information about FAI and helps them to confidently guide patients to formulate appropriate medical decisions based on high-quality information. Copyright © 2014 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  12. Photochemical modeling of emissions trading of highly reactive volatile organic compounds in Houston, Texas. 2. Incorporation of chlorine emissions.

    PubMed

    Wang, Linlin; Thompson, Tammy; McDonald-Buller, Elena C; Allen, David T

    2007-04-01

    As part of the State Implementation Plan for attaining the National Ambient Air Quality Standard for ozone, the Texas Commission of Environmental Quality has created a Highly Reactive Volatile Organic Compounds (HRVOC) Emissions Cap and Trade Program for industrial point sources in the Houston/Galveston/Brazoria area. This series of papers examines the potential air quality impacts of this new emission trading program through photochemical modeling of potential trading scenarios; this paper examines the air quality impact of allowing facilities to trade chlorine emission reductions for HRVOC allocations on a reactivity weighted basis. The simulations indicate that trading of anthropogenic chlorine emission reductions for HRVOC allowances at a single facility or between facilities, in general, resulted in improvements in air quality. Decreases in peak 1-h averaged and 8-h averaged ozone concentrations associated with trading chlorine emissions for HRVOC allocations on a Maximum Incremental Reactivity (MIR) basis were up to 0.74 ppb (0.63%) and 0.56 ppb (0.61%), respectively. Air quality metrics based on population exposure decreased by up to 3.3% and 4.1% for 1-h and 8-h averaged concentrations. These changes are small compared to the maximum changes in ozone concentrations due to the VOC emissions from these sources (5-10 ppb for 8-h averages; up to 30 ppb for 1-h averages) and the chlorine emissions from the sources (5-10 ppb for maximum concentrations over wide areas and up to 70 ppb in localized areas). The simulations indicate that the inclusion of chlorine emissions in the trading program is likely to be beneficial to air quality and is unlikely to cause localized increases in ozone concentrations ("hot spots").

  13. Industrial pollution and the management of river water quality: a model of Kelani River, Sri Lanka.

    PubMed

    Gunawardena, Asha; Wijeratne, E M S; White, Ben; Hailu, Atakelty; Pandit, Ram

    2017-08-19

    Water quality of the Kelani River has become a critical issue in Sri Lanka due to the high cost of maintaining drinking water standards and the market and non-market costs of deteriorating river ecosystem services. By integrating a catchment model with a river model of water quality, we developed a method to estimate the effect of pollution sources on ambient water quality. Using integrated model simulations, we estimate (1) the relative contribution from point (industrial and domestic) and non-point sources (river catchment) to river water quality and (2) pollutant transfer coefficients for zones along the lower section of the river. Transfer coefficients provide the basis for policy analyses in relation to the location of new industries and the setting of priorities for industrial pollution control. They also offer valuable information to design socially optimal economic policy to manage industrialized river catchments.

  14. Meteorological and air pollution modeling for an urban airport

    NASA Technical Reports Server (NTRS)

    Swan, P. R.; Lee, I. Y.

    1980-01-01

    Results are presented of numerical experiments modeling meteorology, multiple pollutant sources, and nonlinear photochemical reactions for the case of an airport in a large urban area with complex terrain. A planetary boundary-layer model which predicts the mixing depth and generates wind, moisture, and temperature fields was used; it utilizes only surface and synoptic boundary conditions as input data. A version of the Hecht-Seinfeld-Dodge chemical kinetics model is integrated with a new, rapid numerical technique; both the San Francisco Bay Area Air Quality Management District source inventory and the San Jose Airport aircraft inventory are utilized. The air quality model results are presented in contour plots; the combined results illustrate that the highly nonlinear interactions which are present require that the chemistry and meteorology be considered simultaneously to make a valid assessment of the effects of individual sources on regional air quality.

  15. Aggregate resource availability in the conterminous United States, including suggestions for addressing shortages, quality, and environmental concerns

    USGS Publications Warehouse

    Langer, William H.

    2011-01-01

    Although potential sources of aggregate are widespread throughout the United States, many sources may not meet certain physical property requirements, such as soundness, hardness, strength, porosity, and specific gravity, or they may contain contaminants or deleterious materials that render them unusable. Encroachment by conflicting land uses, permitting considerations, environmental issues, and societal pressures can prevent or limit development of otherwise suitable aggregate. The use of sustainable aggregate resource management can help ensure an economically viable supply of aggregate. Sustainable aggregate resource management techniques that have successfully been used include (1) protecting potential resources from encroachment; (2) using marginal-quality local aggregate for applications that do not demand a high-quality resource; (3) using substitute materials such as clinker, scoria, and recycled asphalt and concrete; and (4) using rail and water to transport aggregates from remote sources.

  16. Water Quality Assessment of River Soan (Pakistan) and Source Apportionment of Pollution Sources Through Receptor Modeling.

    PubMed

    Nazeer, Summya; Ali, Zeshan; Malik, Riffat Naseem

    2016-07-01

    The present study was designed to determine the spatiotemporal patterns in water quality of River Soan using multivariate statistics. A total of 26 sites were surveyed along River Soan and its associated tributaries during pre- and post-monsoon seasons in 2008. Hierarchical agglomerative cluster analysis (HACA) classified sampling sites into three groups according to their degree of pollution, which ranged from least to high degradation of water quality. Discriminant function analysis (DFA) revealed that alkalinity, orthophosphates, nitrates, ammonia, salinity, and Cd were variables that significantly discriminate among three groups identified by HACA. Temporal trends as identified through DFA revealed that COD, DO, pH, Cu, Cd, and Cr could be attributed for major seasonal variations in water quality. PCA/FA identified six factors as potential sources of pollution of River Soan. Absolute principal component scores using multiple regression method (APCS-MLR) further explained the percent contribution from each source. Heavy metals were largely added through industrial activities (28 %) and sewage waste (28 %), nutrients through agriculture runoff (35 %) and sewage waste (28 %), organic pollution through sewage waste (27 %) and urban runoff (17 %) and macroelements through urban runoff (39 %), and mineralization and sewage waste (30 %). The present study showed that anthropogenic activities are the major source of variations in River Soan. In order to address the water quality issues, implementation of effective waste management measures are needed.

  17. Dual source and dual detector arrays tetrahedron beam computed tomography for image guided radiotherapy.

    PubMed

    Kim, Joshua; Lu, Weiguo; Zhang, Tiezhi

    2014-02-07

    Cone-beam computed tomography (CBCT) is an important online imaging modality for image guided radiotherapy. But suboptimal image quality and the lack of a real-time stereoscopic imaging function limit its implementation in advanced treatment techniques, such as online adaptive and 4D radiotherapy. Tetrahedron beam computed tomography (TBCT) is a novel online imaging modality designed to improve on the image quality provided by CBCT. TBCT geometry is flexible, and multiple detector and source arrays can be used for different applications. In this paper, we describe a novel dual source-dual detector TBCT system that is specially designed for LINAC radiation treatment machines. The imaging system is positioned in-line with the MV beam and is composed of two linear array x-ray sources mounted aside the electrical portal imaging device and two linear arrays of x-ray detectors mounted below the machine head. The detector and x-ray source arrays are orthogonal to each other, and each pair of source and detector arrays forms a tetrahedral volume. Four planer images can be obtained from different view angles at each gantry position at a frame rate as high as 20 frames per second. The overlapped regions provide a stereoscopic field of view of approximately 10-15 cm. With a half gantry rotation, a volumetric CT image can be reconstructed having a 45 cm field of view. Due to the scatter rejecting design of the TBCT geometry, the system can potentially produce high quality 2D and 3D images with less radiation exposure. The design of the dual source-dual detector system is described, and preliminary results of studies performed on numerical phantoms and simulated patient data are presented.

  18. Dual source and dual detector arrays tetrahedron beam computed tomography for image guided radiotherapy

    NASA Astrophysics Data System (ADS)

    Kim, Joshua; Lu, Weiguo; Zhang, Tiezhi

    2014-02-01

    Cone-beam computed tomography (CBCT) is an important online imaging modality for image guided radiotherapy. But suboptimal image quality and the lack of a real-time stereoscopic imaging function limit its implementation in advanced treatment techniques, such as online adaptive and 4D radiotherapy. Tetrahedron beam computed tomography (TBCT) is a novel online imaging modality designed to improve on the image quality provided by CBCT. TBCT geometry is flexible, and multiple detector and source arrays can be used for different applications. In this paper, we describe a novel dual source-dual detector TBCT system that is specially designed for LINAC radiation treatment machines. The imaging system is positioned in-line with the MV beam and is composed of two linear array x-ray sources mounted aside the electrical portal imaging device and two linear arrays of x-ray detectors mounted below the machine head. The detector and x-ray source arrays are orthogonal to each other, and each pair of source and detector arrays forms a tetrahedral volume. Four planer images can be obtained from different view angles at each gantry position at a frame rate as high as 20 frames per second. The overlapped regions provide a stereoscopic field of view of approximately 10-15 cm. With a half gantry rotation, a volumetric CT image can be reconstructed having a 45 cm field of view. Due to the scatter rejecting design of the TBCT geometry, the system can potentially produce high quality 2D and 3D images with less radiation exposure. The design of the dual source-dual detector system is described, and preliminary results of studies performed on numerical phantoms and simulated patient data are presented.

  19. Evaluating the effect of increased pitch, iterative reconstruction and dual source CT on dose reduction and image quality.

    PubMed

    Gariani, Joanna; Martin, Steve P; Botsikas, Diomidis; Becker, Christoph D; Montet, Xavier

    2018-06-14

    To compare radiation dose and image quality of thoracoabdominal scans obtained with a high-pitch protocol (pitch 3.2) and iterative reconstruction (Sinogram Affirmed Iterative Reconstruction) in comparison to standard pitch reconstructed with filtered back projection (FBP) using dual source CT. 114 CT scans (Somatom Definition Flash, Siemens Healthineers, Erlangen, Germany), 39 thoracic scans, 54 thoracoabdominal scans and 21 abdominal scans were performed. Analysis of three protocols was undertaken; pitch of 1 reconstructed with FBP, pitch of 3.2 reconstructed with SAFIRE, pitch of 3.2 with stellar detectors reconstructed with SAFIRE. Objective and subjective image analysis were performed. Dose differences of the protocols used were compared. Dose was reduced when comparing scans with a pitch of 1 reconstructed with FBP to high-pitch scans with a pitch of 3.2 reconstructed with SAFIRE with a reduction of volume CT dose index of 75% for thoracic scans, 64% for thoracoabdominal scans and 67% for abdominal scans. There was a further reduction after the implementation of stellar detectors reflected in a reduction of 36% of the dose-length product for thoracic scans. This was not at the detriment of image quality, contrast-to-noise ratio, signal-to-noise ratio and the qualitative image analysis revealed a superior image quality in the high-pitch protocols. The combination of a high pitch protocol with iterative reconstruction allows significant dose reduction in routine chest and abdominal scans whilst maintaining or improving diagnostic image quality, with a further reduction in thoracic scans with stellar detectors. Advances in knowledge: High pitch imaging with iterative reconstruction is a tool that can be used to reduce dose without sacrificing image quality.

  20. Comparing clinical automated, medical record, and hybrid data sources for diabetes quality measures.

    PubMed

    Kerr, Eve A; Smith, Dylan M; Hogan, Mary M; Krein, Sarah L; Pogach, Leonard; Hofer, Timothy P; Hayward, Rodney A

    2002-10-01

    Little is known about the relative reliability of medical record and clinical automated data, sources commonly used to assess diabetes quality of care. The agreement between diabetes quality measures constructed from clinical automated versus medical record data sources was compared, and the performance of hybrid measures derived from a combination of the two data sources was examined. Medical records were abstracted for 1,032 patients with diabetes who received care from 21 facilities in 4 Veterans Integrated Service Networks. Automated data were obtained from a central Veterans Health Administration diabetes registry containing information on laboratory tests and medication use. Success rates were higher for process measures derived from medical record data than from automated data, but no substantial differences among data sources were found for the intermediate outcome measures. Agreement for measures derived from the medical record compared with automated data was moderate for process measures but high for intermediate outcome measures. Hybrid measures yielded success rates similar to those of medical record-based measures but would have required about 50% fewer chart reviews. Agreement between medical record and automated data was generally high. Yet even in an integrated health care system with sophisticated information technology, automated data tended to underestimate the success rate in technical process measures for diabetes care and yielded different quartile performance rankings for facilities. Applying hybrid methodology yielded results consistent with the medical record but required less data to come from medical record reviews.

  1. Library construction for next-generation sequencing: Overviews and challenges

    PubMed Central

    Head, Steven R.; Komori, H. Kiyomi; LaMere, Sarah A.; Whisenant, Thomas; Van Nieuwerburgh, Filip; Salomon, Daniel R.; Ordoukhanian, Phillip

    2014-01-01

    High-throughput sequencing, also known as next-generation sequencing (NGS), has revolutionized genomic research. In recent years, NGS technology has steadily improved, with costs dropping and the number and range of sequencing applications increasing exponentially. Here, we examine the critical role of sequencing library quality and consider important challenges when preparing NGS libraries from DNA and RNA sources. Factors such as the quantity and physical characteristics of the RNA or DNA source material as well as the desired application (i.e., genome sequencing, targeted sequencing, RNA-seq, ChIP-seq, RIP-seq, and methylation) are addressed in the context of preparing high quality sequencing libraries. In addition, the current methods for preparing NGS libraries from single cells are also discussed. PMID:24502796

  2. Development of multi-pixel x-ray source using oxide-coated cathodes.

    PubMed

    Kandlakunta, Praneeth; Pham, Richard; Khan, Rao; Zhang, Tiezhi

    2017-07-07

    Multiple pixel x-ray sources facilitate new designs of imaging modalities that may result in faster imaging speed, improved image quality, and more compact geometry. We are developing a high-brightness multiple-pixel thermionic emission x-ray (MPTEX) source based on oxide-coated cathodes. Oxide cathodes have high emission efficiency and, thereby, produce high emission current density at low temperature when compared to traditional tungsten filaments. Indirectly heated micro-rectangular oxide cathodes were developed using carbonates, which were converted to semiconductor oxides of barium, strontium, and calcium after activation. Each cathode produces a focal spot on an elongated fixed anode. The x-ray beam ON and OFF control is performed by source-switching electronics, which supplies bias voltage to the cathode emitters. In this paper, we report the initial performance of the oxide-coated cathodes and the MPTEX source.

  3. An Empirically Derived Taxonomy of Organizational Systems

    DTIC Science & Technology

    1985-09-01

    regulation Supply of potential members Share of potential customer market Geographic factors as a handicap Primary sources of income ? Financial condition of...Table 8 (Continued) Variable Item and Source ofData Score Marketing Management 10* Is company currently selling original line or service Yes 1 No 0...years 4 % over 15 years 5 24 Stability of employee job assignments Stable 1 Diverse 0 25 25 Quality demands of market Extremely high 1 High 2 Ordinary

  4. Estimating discharge and non-point source nitrate loading to streams from three end-member pathways using high-frequency water quality and streamflow data

    NASA Astrophysics Data System (ADS)

    Miller, M. P.; Tesoriero, A. J.; Hood, K.; Terziotti, S.; Wolock, D.

    2017-12-01

    The myriad hydrologic and biogeochemical processes taking place in watersheds occurring across space and time are integrated and reflected in the quantity and quality of water in streams and rivers. Collection of high-frequency water quality data with sensors in surface waters provides new opportunities to disentangle these processes and quantify sources and transport of water and solutes in the coupled groundwater-surface water system. A new approach for separating the streamflow hydrograph into three components was developed and coupled with high-frequency specific conductance and nitrate data to estimate time-variable watershed-scale nitrate loading from three end-member pathways - dilute quickflow, concentrated quickflow, and slowflow groundwater - to two streams in central Wisconsin. Time-variable nitrate loads from the three pathways were estimated for periods of up to two years in a groundwater-dominated and a quickflow-dominated stream, using only streamflow and in-stream water quality data. The dilute and concentrated quickflow end-members were distinguished using high-frequency specific conductance data. Results indicate that dilute quickflow contributed less than 5% of the nitrate load at both sites, whereas 89±5% of the nitrate load at the groundwater-dominated stream was from slowflow groundwater, and 84±13% of the nitrate load at the quickflow-dominated stream was from concentrated quickflow. Concentrated quickflow nitrate concentrations varied seasonally at both sites, with peak concentrations in the winter that were 2-3 times greater than minimum concentrations during the growing season. Application of this approach provides an opportunity to assess stream vulnerability to non-point source nitrate loading and expected stream responses to current or changing conditions and practices in watersheds.

  5. Estimating Discharge and Nonpoint Source Nitrate Loading to Streams From Three End-Member Pathways Using High-Frequency Water Quality Data

    NASA Astrophysics Data System (ADS)

    Miller, Matthew P.; Tesoriero, Anthony J.; Hood, Krista; Terziotti, Silvia; Wolock, David M.

    2017-12-01

    The myriad hydrologic and biogeochemical processes taking place in watersheds occurring across space and time are integrated and reflected in the quantity and quality of water in streams and rivers. Collection of high-frequency water quality data with sensors in surface waters provides new opportunities to disentangle these processes and quantify sources and transport of water and solutes in the coupled groundwater-surface water system. A new approach for separating the streamflow hydrograph into three components was developed and coupled with high-frequency nitrate data to estimate time-variable nitrate loads from chemically dilute quick flow, chemically concentrated quick flow, and slowflow groundwater end-member pathways for periods of up to 2 years in a groundwater-dominated and a quick-flow-dominated stream in central Wisconsin, using only streamflow and in-stream water quality data. The dilute and concentrated quick flow end-members were distinguished using high-frequency specific conductance data. Results indicate that dilute quick flow contributed less than 5% of the nitrate load at both sites, whereas 89 ± 8% of the nitrate load at the groundwater-dominated stream was from slowflow groundwater, and 84 ± 25% of the nitrate load at the quick-flow-dominated stream was from concentrated quick flow. Concentrated quick flow nitrate concentrations varied seasonally at both sites, with peak concentrations in the winter that were 2-3 times greater than minimum concentrations during the growing season. Application of this approach provides an opportunity to assess stream vulnerability to nonpoint source nitrate loading and expected stream responses to current or changing conditions and practices in watersheds.

  6. Modeling Study on Air Quality Improvement due to Mobile Source Emission control Plan in Seoul Metropolitan Area

    NASA Astrophysics Data System (ADS)

    Kim, Y. J.; Sunwoo, Y.; Hwang, I.; Song, S.; Sin, J.; Kim, D.

    2015-12-01

    A very high population and corresponding high number of vehicles in the Seoul Metropolitan Area (SMA) are aggravating the air quality of this region. The Korean government continues to make concerted efforts to improve air quality. One of the major policies that the Ministry of Environment of Korea enforced is "The Special Act for Improvement of Air Quality in SMA" and "The 1st Air Quality Management Plan of SMA". Mobile Source emission controls are an important part of the policy. Thus, it is timely to evaluate the air quality improvement due to the controls. Therefore, we performed a quantitative analysis of the difference in air quality using the Community Multiscale Air Quality (CMAQ) model and December, 2011 was set as the target period to capture the impact of the above control plans. We considered four fuel-type vehicle emission scenarios and compared the air quality improvement differences between them. The scenarios are as follows: no-control, gasoline vehicle control only, diesel vehicle control only, and control of both; utilizing the revised mobile source emissions from the Clean Air Policy Support System (CAPSS), which is the national emission inventory reflecting current policy.In order to improve the accuracy of the modeling data, we developed new temporal allocation coefficients based on traffic volume observation data and spatially reallocated the mobile source emissions using vehicle flow survey data. Furthermore, we calculated the PM10 and PM2.5 emissions of gasoline vehicles which is omitted in CAPSS.The results of the air quality modeling shows that vehicle control plans for both gasoline and diesel lead to a decrease of 0.65ppb~8.75ppb and 0.02㎍/㎥~7.09㎍/㎥ in NO2 and PM10 monthly average concentrations, respectively. The large percentage decreases mainly appear near the center of the metropolis. However, the largest NO2 decrease percentages are found in the northeast region of Gyeonggi-do, which is the province that surrounds the capital of Seoul. Comparing the results between the different scenarios, diesel vehicle control impact dominates relative to the impact of gasoline control. The diesel-only reduction plan shows that NO2 and PM10 improved by 2.93ppb and 3.32㎍/㎥, respectively.

  7. Monitoring coastal marine waters for spore-forming bacteria of faecal and soil origin to determine point from non-point source pollution.

    PubMed

    Fujioka, R S

    2001-01-01

    The US Environmental Protection Agency (USEPA) and the World Health Organization (WHO) have established recreational water quality standards limiting the concentrations of faecal indicator bacteria (faecal coliform, E. coli, enterococci) to ensure that these waters are safe for swimming. In the application of these hygienic water quality standards, it is assumed that there are no significant environmental sources of these faecal indicator bacteria which are unrelated to direct faecal contamination. However, we previously reported that these faecal indicator bacteria are able to grow in the soil environment of humid tropical island environments such as Hawaii and Guam and are transported at high concentrations into streams and storm drains by rain. Thus, streams and storm drains in Hawaii contain consistently high concentrations of faecal indicator bacteria which routinely exceed the EPA and WHO recreational water quality standards. Since, streams and storm drains eventually flow out to coastal marine waters, we hypothesize that all the coastal beaches which receive run-off from streams and storm drains will contain elevated concentrations of faecal indicator bacteria. To test this hypothesis, we monitored the coastal waters at four beaches known to receive water from stream or storm drains for salinity, turbidity, and used the two faecal indicator bacteria (E. coli, enterococci) to establish recreational water quality standards. To determine if these coastal waters are contaminated with non-point source pollution (streams) or with point source pollution (sewage effluent), these same water samples were also assayed for spore-forming bacteria of faecal origin (Cl. perfringens) and of soil origin (Bacillus species). Using this monitoring strategy it was possible to determine when coastal marine waters were contaminated with non-point source pollution and when coastal waters were contaminated with point source pollution. The results of this study are most likely applicable to all countries in the warm and humid region of the world.

  8. Non-destructive measurements of cottonseed nutritional trait diversity in the US National Cotton Germplasm Collection

    USDA-ARS?s Scientific Manuscript database

    Recent studies have suggested that cottonseed (Gossypium spp.) has the potential to contribute to the effort against world hunger, particularly by providing a high quality protein source. This report analyzed the diversity in protein content and other seed quality factors in the US National Cotton ...

  9. Non-destructive measurements of cottonseed nutritional trait diversity in the US National Cotton Germplasm Collection

    USDA-ARS?s Scientific Manuscript database

    Recent studies have suggested that cottonseed (Gossypium spp.) has the potential to contribute to the effort against world hunger, particularly by providing a high-quality protein source. This report analyzed the diversity in protein content and other seed quality factors in the U.S. National Cotton...

  10. High Quality in Primary Humanities: Insights from the UK's School Inspectorates

    ERIC Educational Resources Information Center

    Catling, Simon

    2017-01-01

    The school inspectorates of the four jurisdictions of the UK are sources of evidence about the quality of humanities teaching, learning and curriculum in primary schools. The term "humanities" usually refers to the subjects of geography, history and Religious Education, but here they are considered holistically, not separately. Discrete…

  11. What Do We Learn from Recall Consumption Data?

    ERIC Educational Resources Information Center

    Battistin, Erich; Miniaci, Raffaele; Weber, Guglielmo

    2003-01-01

    In this paper, we use two complementary Italian data sources (the 1995 ISTAT and Bank of Italy household surveys) to generate household-specific nondurable expenditure in the Bank of Italy sample that contains relatively high-quality income data. We show that food expenditure data are of comparable quality and informational content across the two…

  12. ANMCO/AIIC/SIT Consensus Information Document: definition, precision, and suitability of electrocardiographic signals of electrocardiographs, ergometry, Holter electrocardiogram, telemetry, and bedside monitoring systems.

    PubMed

    Gulizia, Michele Massimo; Casolo, Giancarlo; Zuin, Guerrino; Morichelli, Loredana; Calcagnini, Giovanni; Ventimiglia, Vincenzo; Censi, Federica; Caldarola, Pasquale; Russo, Giancarmine; Leogrande, Lorenzo; Franco Gensini, Gian

    2017-05-01

    The electrocardiogram (ECG) signal can be derived from different sources. These include systems for surface ECG, Holter monitoring, ergometric stress tests, and telemetry systems and bedside monitoring of vital parameters, which are useful for rhythm and ST-segment analysis and ECG screening of electrical sudden cardiac death predictors. A precise ECG diagnosis is based upon correct recording, elaboration, and presentation of the signal. Several sources of artefacts and potential external causes may influence the quality of the original ECG waveforms. Other factors that may affect the quality of the information presented depend upon the technical solutions employed to improve the signal. The choice of the instrumentations and solutions used to offer a high-quality ECG signal are, therefore, of paramount importance. Some requirements are reported in detail in scientific statements and recommendations. The aim of this consensus document is to give scientific reference for the choice of systems able to offer high quality ECG signal acquisition, processing, and presentation suitable for clinical use.

  13. ANMCO/AIIC/SIT Consensus Information Document: definition, precision, and suitability of electrocardiographic signals of electrocardiographs, ergometry, Holter electrocardiogram, telemetry, and bedside monitoring systems

    PubMed Central

    Casolo, Giancarlo; Zuin, Guerrino; Morichelli, Loredana; Calcagnini, Giovanni; Ventimiglia, Vincenzo; Censi, Federica; Caldarola, Pasquale; Russo, Giancarmine; Leogrande, Lorenzo; Franco Gensini, Gian

    2017-01-01

    Abstract The electrocardiogram (ECG) signal can be derived from different sources. These include systems for surface ECG, Holter monitoring, ergometric stress tests, and telemetry systems and bedside monitoring of vital parameters, which are useful for rhythm and ST-segment analysis and ECG screening of electrical sudden cardiac death predictors. A precise ECG diagnosis is based upon correct recording, elaboration, and presentation of the signal. Several sources of artefacts and potential external causes may influence the quality of the original ECG waveforms. Other factors that may affect the quality of the information presented depend upon the technical solutions employed to improve the signal. The choice of the instrumentations and solutions used to offer a high-quality ECG signal are, therefore, of paramount importance. Some requirements are reported in detail in scientific statements and recommendations. The aim of this consensus document is to give scientific reference for the choice of systems able to offer high quality ECG signal acquisition, processing, and presentation suitable for clinical use. PMID:28751842

  14. Microstructured fibres: a positive impact on defence technology?

    NASA Astrophysics Data System (ADS)

    O'Driscoll, E. J.; Watson, M. A.; Delmonte, T.; Petrovich, M. N.; Feng, X.; Flanagan, J. C.; Hayes, J. R.; Richardson, D. J.

    2006-09-01

    In this paper we seek to assess the potential impact of microstructured fibres for security and defence applications. Recent literature has presented results on using microstructured fibre for delivery of high power, high quality radiation and also on the use of microstructured fibre for broadband source generation. Whilst these two applications may appear contradictory to one another the inherent design flexibility of microstructured fibres allows fibres to be fabricated for the specific application requirements, either minimising (for delivery) or maximising (for broadband source generation) the nonlinear effects. In platform based laser applications such as infrared counter measures, remote sensing and laser directed-energy weapons, a suitable delivery fibre providing high power, high quality light delivery would allow a laser to be sited remotely from the sensor/device head. This opens up the possibility of several sensor/device types sharing the same multi-functional laser, thus reducing the complexity and hence the cost of such systems. For applications requiring broadband source characteristics, microstructured fibres can also offer advantages over conventional sources. By exploiting the nonlinear effects it is possible to realise a multifunctional source for applications such as active hyperspectral imaging, countermeasures, and biochemical sensing. These recent results suggest enormous potential for these novel fibre types to influence the next generation of photonic systems for security and defence applications. However, it is important to establish where the fibres can offer the greatest advantages and what research still needs to be done to drive the technology towards real platform solutions.

  15. INCORPORATION OF DNA BARCODES INTO ASSESSMENTS OF THE BIOLOGICAL INTEGRITY OF AQUATIC ECOSYSTEMS: PRECISION, ACCURACY AND COST

    EPA Science Inventory

    Historically, water quality assessments in the United States primarily focused on water chemistry assays at or near discharge sources. As it has become clear that waters also can be highly impaired from dispersed (i.e., non-point source) chemicals and non-chemical impacts, direc...

  16. Sources of Support and Psychological Distress among Academically Successful Inner-City Youth.

    ERIC Educational Resources Information Center

    Kenny, Maureen E.; Gallagher, Laura A.; Alvarez-Salvat, Rose; Silsby, John

    2002-01-01

    In Study 1, the relationships between parental attachment, academic achievement, and distress were tested with a sample of academically successful inner-city high school students (N=100). Affective quality of maternal attachment was positively associated with grade point average. In Study 2, case examples provided an examination of sources of…

  17. Understanding DOC Mobilization Dynamics Through High Frequency Measurements in a Headwater Catchment

    NASA Astrophysics Data System (ADS)

    Werner, B.; Musolff, A.; Lechtenfeld, O.; de Rooij, G. H.; Fleckenstein, J. H.

    2017-12-01

    Increasing dissolved organic carbon (DOC) exports from headwater catchments impact the quality of downstream waters and pose challenges to water supply. The importance of riparian zones for DOC export from catchments in humid, temperate climates has generally been acknowledged, but the hydrological controls and biogeochemical factors that govern mobilization of DOC from riparian zones remain elusive. By analyzing high-frequency time series of UV-VIS based water quality we therefore aim at a better understanding on temporal dynamics of DOC mobilization and exports. In a first step a one year high frequency (15 minutes) data set from a headwater catchment in the Harz Mountains (Germany) was systematically analyzed for event-based patterns in DOC concentrations. Here, a simplistic linear model was generated to explain DOC concentration level and variability in the stream. Furthermore, spectral (e.g. slopes and SUVA254) and molecular (FT-ICR-MS) characterization of DOC was used to fingerprint in-stream DOC during events. Continuous DOC concentrations were best predicted (R², NSE = 0.53) by instantaneous discharge (Q) and antecede wetness conditions of the last 30 days (AWC30 = Precip.30/PET30) as well as mean air temperature (Tmean30) and mean discharge (Qmean30) of the preceding 30 days. Analyses of 36 events revealed seasonal trends for the slope, intercept and R² of linear log(DOC)-log(Q) regressions that can be best explained by the mean air temperature of the preceding 15 days. Continuously available optical DOC quality parameters SUVA254 and spectral slope (275 nm - 295 nm) systematically changed with shifts in discharge and in DOC concentration. This is underlined by selected FT-ICR-MS measurements indicating higher DOC aromaticity and oxygen content at high flow conditions. The change of DOC quality parameters during events indicate a shift in the activated source zones: DOC with a different quality was mobilized during high flow conditions when higher groundwater levels connected formerly disconnected DOC source zones to the stream. We conclude that the high concentration variability of DOC can be explained by a few controlling variables only. These variables can be linked to event-based DOC source activation and more seasonal controls of DOC production.

  18. All Source Solution Decision Support Products Created for Stennis Space Center in Response to Hurricane Katrina

    NASA Technical Reports Server (NTRS)

    Ross, Kenton W.; Graham, William D.

    2007-01-01

    In the aftermath of Hurricane Katrina and in response to the needs of SSC (Stennis Space Center), NASA required the generation of decision support products with a broad range of geospatial inputs. Applying a systems engineering approach, the NASA ARTPO (Applied Research and Technology Project Office) at SSC evaluated the Center's requirements and source data quality. ARTPO identified data and information products that had the potential to meet decision-making requirements; included were remotely sensed data ranging from high-spatial-resolution aerial images through high-temporal-resolution MODIS (Moderate Resolution Imaging Spectroradiometer) products. Geospatial products, such as FEMA's (Federal Emergency Management Agency's) Advisory Base Flood Elevations, were also relevant. Where possible, ARTPO applied SSC calibration/validation expertise to both clarify the quality of various data source options and to validate that the inputs that were finally chosen met SSC requirements. ARTPO integrated various information sources into multiple decision support products, including two maps: Hurricane Katrina Inundation Effects at Stennis Space Center (highlighting surge risk posture) and Vegetation Change In and Around Stennis Space Center: Katrina and Beyond (highlighting fire risk posture).

  19. Possible source term of high concentrations of mecoprop-p in leachate and water quality: impact of climate change, public use and disposal.

    PubMed

    Idowu, I A; Alkhaddar, R M; Atherton, W

    2014-08-01

    Mecoprop-p herbicide is often found in wells and water abstractions in many areas around Europe, the UK inclusive. There is a growing environmental and public health concern about mecoprop-p herbicide pollution in ground and surface water in England. Reviews suggest that extensive work has been carried out on the contribution of mecoprop-p herbicides from agricultural use whilst more work needs to be carried out on the contribution of mecoprop-p herbicide from non-agricultural use. The study covers two landfill sites in Weaver/Gowy Catchment. Mecoprop-p herbicide concentrations in the leachate quality range between 0.06 and 290 microg l1 in cells. High concentration ofmecoprop-p herbicide in the leachate quality suggests that there is a possible source term in the waste stream. This paper addresses the gap by exploring possible source terms of mecoprop-p herbicide contamination on landfill sites and evaluates the impact of public purchase, use and disposal alongside climate change on seasonal variations in mecoprop-p concentrations. Mecoprop-p herbicide was found to exceed the EU drinking water quality standards at the unsaturated zone/aquifer with observed average concentrations ranging between 0.005 and 7.96 microg l1. A route map for mecoprop-p herbicide source term contamination is essential for mitigation and pollution management with emphasis on both consumer and producer responsibility towards use of mecoprop-p product. In addition, improvement in data collection on mecoprop-p concentrations and detailed seasonal herbicide sales for non-agricultural purposes are needed to inform the analysis and decision process.

  20. Water for human and livestock consumption in rural settings of Ethiopia: assessments of quality and health aspects.

    PubMed

    Amenu, Kebede; Markemann, André; Valle Zárate, Anne

    2013-11-01

    The study aimed to assess the quality and health aspects of water intended for human and livestock consumption in two rural districts of the Rift Valley of Ethiopia. The study involved two parts: the first consisted of a questionnaire survey and farmers' group discussions, complemented by secondary health data, and the second part determined the chemical (total dissolved solids, pH, manganese, hexa-valent chromium, fluoride) and microbiological quality of different water sources during dry and wet seasons. The result showed a lack of sustainable access to safe water in the communities. Industrial pollution and mismanagement of water sources by human and livestock was found to be a source of potential health risk. Potentially linked human health problems like malaria, diarrhoea and gastrointestinal parasites were common in the districts. Overall, 76% of the assessed water sources (n = 25) failed to comply with World Health Organization guidelines for human drinking water, for at least one assessed parameter, mostly irrespective of the season. The non-compliance was mainly attributed to Escherichia coli contamination and/or high fluoride concentration. At least 20% of the water samples were also found to be unfit for livestock consumption based on assessed chemical parameters in both dry and wet seasons. To minimize the health risk associated with mismanagement and poor quality of water sources in the area, targeted action in the protection of surface water sources should be given priority.

  1. Differentials in measures of dietary quality among adolescents in Jimma zone, Southwest Ethiopia.

    PubMed

    Belachew, Tefera; Hadley, Craig; Lindstrom, David

    2008-04-01

    nutritionally adequate, safe and good quality diet is essential for human health, school performance, and employment output. Dietary diversity, consumption of animal source food and food variety score are commonly used measures of dietary quality. This study aimed to assess gender & sociodemographic differentials in measures of dietary quality among male and female adolescents. As part of the Jimma Family Longitudinal Study of Youth households with a youth between 13-17 years were randomly sampled from Jimma Town, the small towns and nearby rural Kebeles. Dietary diversity was assessed by asking youth about the consumption of 32 different food items included in the survey, which were regrouped into four major food groups. The four groups included animal source foods (10 items), fruits-vegetables (11 items), cereals (7 items) and legumes-nuts (2 items). From these food groups, measures of dietary diversity, food variety score, and animal source food consumption were calculated Logistic regression model was done using SPSS for windows version 12.0.1 to determine the odds ratios and predicted probabilities of consuming diversified diet. Overall, 826 (39.7%), 819 (39.4%) and 955 (45.9%) of adolescents had low quality diet as measured by dietary diversity, consumption of animal source food and food variety score, respectively. Predictors of a diversi-fied diet consumption were male gender, (1.3 OR, 95% CI 1.1, 1, 5), living in small towns (1.7 OR (95% 1.3, 2.1) and being a member of household in the high-income quartile (2.1 OR 95% CI 1.5, 2.8). Intake of animal source foods was associated with the highest level of education achieved in the household (1.4 OR 95% CI: 1.1, 1.8), being male (1.3 OR 95% CI: 1.1, 1.5), being in a households with highest income quartile (2.3 OR 95% CI: 1.6, 3.1). Adolescents who lived in households with the highest income quartile and those who lived in the small towns were 1.6 and 1.4 times more likely to have high food variety score. Large proportion of adolescents consumed low quality diets, which may effect on their education and work productivity and contribute to an intergenerational cycle of malnutrition. Interventions designed to improve dietary quality should target female adolescents, those in the poorest households, and households with low levels of education. Rural areas should also be targeted Thus targeted interventions to promote dietary quality and programmatic interventions to increases schooling may positively influence dietary quality in this area.

  2. Assessing the sources of high fecal coliform levels at an urban tropical beach

    PubMed Central

    Davino, Aline Mendonça Cavalcante; de Melo, Milena Bandeira; Caffaro, Roberto Augusto

    2015-01-01

    Recreational water quality is commonly assessed by microbial indicators such as fecal coliforms. Maceió is the capital of Alagoas state, located in tropical northeastern Brazil. Its beaches are considered as the most beautiful urban beaches in the country. Jatiúca Beach in Maceió was found to be unsuitable for bathing continuously during the year of 2011. The same level of contamination was not observed in surrounding beaches. The aim of this study was to initiate the search for the sources of these high coliform levels, so that contamination can be eventually mitigated. We performed a retrospective analysis of historical results of fecal coliform concentrations from 2006 to 2012 at five monitoring stations located in the study region. Results showed that Jatiúca Beach consistently presented the worst quality among the studied beaches. A field survey was conducted to identify existing point and non-point sources of pollution in the area. Monitoring in the vicinity of Jatiúca was spatially intensified. Fecal coliform concentrations were categorized according to tide range and tide stage. A storm drain located in northern Jatiúca was identified as the main point source of the contamination. However, fecal coliform concentrations at Jatiúca were high during high tides and spring tides even when this point source was inactive (no rainfall). We hypothesize that high fecal coliform levels in Jatiúca Beach may also be caused by aquifer contamination or, more likely, from tide washing of contaminated sand. Both of these hypotheses will be further investigated. PMID:26691459

  3. Assessing the sources of high fecal coliform levels at an urban tropical beach.

    PubMed

    Davino, Aline Mendonça Cavalcante; de Melo, Milena Bandeira; Caffaro Filho, Roberto Augusto

    2015-01-01

    Recreational water quality is commonly assessed by microbial indicators such as fecal coliforms. Maceió is the capital of Alagoas state, located in tropical northeastern Brazil. Its beaches are considered as the most beautiful urban beaches in the country. Jatiúca Beach in Maceió was found to be unsuitable for bathing continuously during the year of 2011. The same level of contamination was not observed in surrounding beaches. The aim of this study was to initiate the search for the sources of these high coliform levels, so that contamination can be eventually mitigated. We performed a retrospective analysis of historical results of fecal coliform concentrations from 2006 to 2012 at five monitoring stations located in the study region. Results showed that Jatiúca Beach consistently presented the worst quality among the studied beaches. A field survey was conducted to identify existing point and non-point sources of pollution in the area. Monitoring in the vicinity of Jatiúca was spatially intensified. Fecal coliform concentrations were categorized according to tide range and tide stage. A storm drain located in northern Jatiúca was identified as the main point source of the contamination. However, fecal coliform concentrations at Jatiúca were high during high tides and spring tides even when this point source was inactive (no rainfall). We hypothesize that high fecal coliform levels in Jatiúca Beach may also be caused by aquifer contamination or, more likely, from tide washing of contaminated sand. Both of these hypotheses will be further investigated.

  4. CellProfiler Tracer: exploring and validating high-throughput, time-lapse microscopy image data.

    PubMed

    Bray, Mark-Anthony; Carpenter, Anne E

    2015-11-04

    Time-lapse analysis of cellular images is an important and growing need in biology. Algorithms for cell tracking are widely available; what researchers have been missing is a single open-source software package to visualize standard tracking output (from software like CellProfiler) in a way that allows convenient assessment of track quality, especially for researchers tuning tracking parameters for high-content time-lapse experiments. This makes quality assessment and algorithm adjustment a substantial challenge, particularly when dealing with hundreds of time-lapse movies collected in a high-throughput manner. We present CellProfiler Tracer, a free and open-source tool that complements the object tracking functionality of the CellProfiler biological image analysis package. Tracer allows multi-parametric morphological data to be visualized on object tracks, providing visualizations that have already been validated within the scientific community for time-lapse experiments, and combining them with simple graph-based measures for highlighting possible tracking artifacts. CellProfiler Tracer is a useful, free tool for inspection and quality control of object tracking data, available from http://www.cellprofiler.org/tracer/.

  5. Information Expensiveness Perceived by Vietnamese Patients with Respect to Healthcare Provider's Choice.

    PubMed

    Quan-Hoang, Vuong

    2016-10-01

    Patients have to acquire information to support their decision on choosing a suitable healthcare provider. But in developing countries like Vietnam, accessibility issues remain an obstacle, thus adversely affect both quality and costliness of healthcare information. Vietnamese use both sources from health professionals and friends/relatives, especially when quality of the Internet-based cheaper sources appear to be still questionable. The search of information from both professionals and friends/relatives incurs some cost, which can be viewed as low or high depending low or high accessibility to the sources. These views potentially affect their choices. To investigate the effects that medical/health services information on perceived expensiveness of patients' labor costs. Two related objectives are a) establishing empirical relations between accessibility to sources and expensiveness; and, b) probabilistic trends of probabilities for perceived expensiveness. There is evidence for established relations among the variables "Convexp" and "Convrel" (all p's < 0.01), indicating that both information sources (experts and friends/relatives) have influence on patients perception of information expensiveness. The use of experts source tends to increase the probability of perceived expensiveness. a) Probabilistic trends show Vietnamese patients have propensity to value healthcare information highly and do not see it as "expensive"; b) The majority of Vietnamese households still take non-professional advices at their own risks; c) There is more for the public healthcare information system to do to reduce costliness and risk of information. The Internet-based health service users communities cannot replace this system.

  6. Microbial quality of improved drinking water sources: evidence from western Kenya and southern Vietnam.

    PubMed

    Grady, Caitlin A; Kipkorir, Emmanuel C; Nguyen, Kien; Blatchley, E R

    2015-06-01

    In recent decades, more than 2 billion people have gained access to improved drinking water sources thanks to extensive effort from governments, and public and private sector entities. Despite this progress, many water sector development interventions do not provide access to safe water or fail to be sustained for long-term use. The authors examined drinking water quality of previously implemented water improvement projects in three communities in western Kenya and three communities in southern Vietnam. The cross-sectional study of 219 households included measurements of viable Escherichia coli. High rates of E. coli prevalence in these improved water sources were found in many of the samples. These findings suggest that measures above and beyond the traditional 'improved source' definition may be necessary to ensure truly safe water throughout these regions.

  7. DOE Office of Scientific and Technical Information (OSTI.GOV)

    BENNETT,D.B.; PAQUETTE,D.E.; KLAUS,K.

    The BNL water supply system meets all water quality standards and has sufficient pumping and storage capacity to meet current and anticipated future operational demands. Because BNL's water supply is drawn from the shallow Upper Glacial aquifer, BNL's source water is susceptible to contamination. The quality of the water supply is being protected through (1) a comprehensive program of engineered and operational controls of existing aquifer contamination and potential sources of new contamination, (2) groundwater monitoring, and (3) potable water treatment. The BNL Source Water Assessment found that the source water for BNL's Western Well Field (comprised of Supply Wellsmore » 4, 6, and 7) has relatively few threats of contamination and identified potential sources are already being carefully managed. The source water for BNL's Eastern Well Field (comprised of Supply Wells 10, 11, and 12) has a moderate number of threats to water quality, primarily from several existing volatile organic compound and tritium plumes. The g-2 Tritium Plume and portions of the Operable Unit III VOC plume fall within the delineated source water area for the Eastern Well Field. In addition, portions of the much slower migrating strontium-90 plumes associated with the Brookhaven Graphite Research Reactor, Waste Concentration Facility and Building 650 lie within the Eastern source water area. However, the rate of travel in the aquifer for strontium-90 is about one-twentieth of that for tritium and volatile organic compounds. The Laboratory has been carefully monitoring plume migration, and has made adjustments to water supply operations. Although a number of BNL's water supply wells were impacted by VOC contamination in the late 1980s, recent routine analysis of water samples from BNL's supply wells indicate that no drinking water standards have been reached or exceeded. The high quality of the water supply strongly indicates that the operational and engineered controls implemented over the past ten years have effectively protected the quality of the water supply.« less

  8. High-resolution monitoring of stormwater quality in an urbanising catchment in the United Kingdom during the 2013/2014 winter storms

    NASA Astrophysics Data System (ADS)

    McGrane, S. J.; Hutchins, M. G.; Kjeldsen, T. R.; Miller, J. D.; Bussi, G.; Loewenthal, M.

    2015-12-01

    Urban areas are widely recognised as a key source of contaminants entering our freshwater systems, yet in spite of this, our understanding of stormwater quality dynamics remains limited. The development of in-situ, high-resolution monitoring equipment has revolutionised our capability to capture flow and water quality data at a sub-hourly resolution, enabling us to potentially enhance our understanding of hydrochemical variations from contrasting landscapes during storm events. During the winter of 2013/2014, the United Kingdom experienced a succession of intense storm events, where the south of the country experienced 200% of the average rainfall, resulting in widespread flooding across the Thames basin. We applied high-frequency (15 minute resolution) water quality monitoring across ten contrasting subcatchments (including rural, urban and mixed land-use catchments), seeking to classify the disparity in water quality conditions both within- and between events. Rural catchments increasingly behave like "urban" catchments as soils wet up and become increasingly responsive to subsequent events, however water quality response during the winter months remains limited. By contrast, increasingly urban catchments yield greater contaminant loads during events, and pre-event baseline chemistry highlights a resupply source in dense urban catchments. Wastewater treatment plants were shown to dominate baseline chemistry during low-flow events but also yield a considerable impact on stormwater outputs during peak-flow events, as hydraulic push results in the outflow of untreated solid wastes into the river system. Results are discussed in the context of water quality policy; urban growth scenarios and BMP for stormwater runoff in contrasting landscapes.

  9. Village-Level Identification of Nitrate Sources: Collaboration of Experts and Local Population in Benin, Africa

    NASA Astrophysics Data System (ADS)

    Crane, P.; Silliman, S. E.; Boukari, M.; Atoro, I.; Azonsi, F.

    2005-12-01

    Deteriorating groundwater quality, as represented by high nitrates, in the Colline province of Benin, West Africa was identified by the Benin national water agency, Direction Hydraulique. For unknown reasons the Colline province had consistently higher nitrate levels than any other region of the country. In an effort to address this water quality issue, a collaborative team was created that incorporated professionals from the Universite d'Abomey-Calavi (Benin), the University of Notre Dame (USA), Direction l'Hydraulique (a government water agency in Benin), Centre Afrika Obota (an educational NGO in Benin), and the local population of the village of Adourekoman. The goals of the project were to: (i) identify the source of nitrates, (ii) test field techniques for long term, local monitoring, and (iii) identify possible solutions to the high levels of groundwater nitrates. In order to accomplish these goals, the following methods were utilized: regional sampling of groundwater quality, field methods that allowed the local population to regularly monitor village groundwater quality, isotopic analysis, and sociological methods of surveys, focus groups, and observations. It is through the combination of these multi-disciplinary methods that all three goals were successfully addressed leading to preliminary identification of the sources of nitrates in the village of Adourekoman, confirmation of utility of field techniques, and initial assessment of possible solutions to the contamination problem.

  10. Assessing data quality and the variability of source data verification auditing methods in clinical research settings.

    PubMed

    Houston, Lauren; Probst, Yasmine; Martin, Allison

    2018-05-18

    Data audits within clinical settings are extensively used as a major strategy to identify errors, monitor study operations and ensure high-quality data. However, clinical trial guidelines are non-specific in regards to recommended frequency, timing and nature of data audits. The absence of a well-defined data quality definition and method to measure error undermines the reliability of data quality assessment. This review aimed to assess the variability of source data verification (SDV) auditing methods to monitor data quality in a clinical research setting. The scientific databases MEDLINE, Scopus and Science Direct were searched for English language publications, with no date limits applied. Studies were considered if they included data from a clinical trial or clinical research setting and measured and/or reported data quality using a SDV auditing method. In total 15 publications were included. The nature and extent of SDV audit methods in the articles varied widely, depending upon the complexity of the source document, type of study, variables measured (primary or secondary), data audit proportion (3-100%) and collection frequency (6-24 months). Methods for coding, classifying and calculating error were also inconsistent. Transcription errors and inexperienced personnel were the main source of reported error. Repeated SDV audits using the same dataset demonstrated ∼40% improvement in data accuracy and completeness over time. No description was given in regards to what determines poor data quality in clinical trials. A wide range of SDV auditing methods are reported in the published literature though no uniform SDV auditing method could be determined for "best practice" in clinical trials. Published audit methodology articles are warranted for the development of a standardised SDV auditing method to monitor data quality in clinical research settings. Copyright © 2018. Published by Elsevier Inc.

  11. A high-throughput system for high-quality tomographic reconstruction of large datasets at Diamond Light Source

    PubMed Central

    Atwood, Robert C.; Bodey, Andrew J.; Price, Stephen W. T.; Basham, Mark; Drakopoulos, Michael

    2015-01-01

    Tomographic datasets collected at synchrotrons are becoming very large and complex, and, therefore, need to be managed efficiently. Raw images may have high pixel counts, and each pixel can be multidimensional and associated with additional data such as those derived from spectroscopy. In time-resolved studies, hundreds of tomographic datasets can be collected in sequence, yielding terabytes of data. Users of tomographic beamlines are drawn from various scientific disciplines, and many are keen to use tomographic reconstruction software that does not require a deep understanding of reconstruction principles. We have developed Savu, a reconstruction pipeline that enables users to rapidly reconstruct data to consistently create high-quality results. Savu is designed to work in an ‘orthogonal’ fashion, meaning that data can be converted between projection and sinogram space throughout the processing workflow as required. The Savu pipeline is modular and allows processing strategies to be optimized for users' purposes. In addition to the reconstruction algorithms themselves, it can include modules for identification of experimental problems, artefact correction, general image processing and data quality assessment. Savu is open source, open licensed and ‘facility-independent’: it can run on standard cluster infrastructure at any institution. PMID:25939626

  12. The Endockscope Using Next Generation Smartphones: "A Global Opportunity".

    PubMed

    Tse, Christina; Patel, Roshan M; Yoon, Renai; Okhunov, Zhamshid; Landman, Jaime; Clayman, Ralph V

    2018-06-02

    The Endockscope combines a smartphone, a battery powered flashlight and a fiberoptic cystoscope allowing for mobile videocystoscopy. We compared conventional videocystoscopy to the Endockscope paired with next generation smartphones in an ex-vivo porcine bladder model to evaluate its image quality. The Endockscope consists of a three-dimensional (3D) printed attachment that connects a smartphone to a flexible fiberoptic cystoscope plus a 1000 lumen light-emitting diode (LED) cordless light source. Video recordings of porcine cystoscopy with a fiberoptic flexible cystoscope (Storz) were captured for each mobile device (iPhone 6, iPhone 6S, iPhone 7, Samsung S8, and Google Pixel) and for the high-definition H3-Z versatile camera (HD) set-up with both the LED light source and the xenon light (XL) source. Eleven faculty urologists, blinded to the modality used, evaluated each video for image quality/resolution, brightness, color quality, sharpness, overall quality, and acceptability for diagnostic use. When comparing the Endockscope coupled to an Galaxy S8, iPhone 7, and iPhone 6S with the LED portable light source to the HD camera with XL, there were no statistically significant differences in any metric. 82% and 55% of evaluators considered the iPhone 7 + LED light source and iPhone 6S + LED light, respectively, appropriate for diagnostic purposes as compared to 100% who considered the HD camera with XL appropriate. The iPhone 6 and Google Pixel coupled with the LED source were both inferior to the HD camera with XL in all metrics. The Endockscope system with a LED light source when coupled with either an iPhone 7 or Samsung S8 (total cost: $750) is comparable to conventional videocystoscopy with a standard camera and XL light source (total cost: $45,000).

  13. Systematic reviews and meta-analyses on psoriasis: role of funding sources, conflict of interest and bibliometric indices as predictors of methodological quality.

    PubMed

    Gómez-García, F; Ruano, J; Aguilar-Luque, M; Gay-Mimbrera, J; Maestre-Lopez, B; Sanz-Cabanillas, J L; Carmona-Fernández, P J; González-Padilla, M; Vélez García-Nieto, A; Isla-Tejera, B

    2017-06-01

    The quality of systematic reviews and meta-analyses on psoriasis, a chronic inflammatory skin disease that severely impairs quality of life and is associated with high costs, remains unknown. To assess the methodological quality of systematic reviews published on psoriasis. After a comprehensive search in MEDLINE, Embase and the Cochrane Database (PROSPERO: CDR42016041611), the quality of studies was assessed by two raters using the Assessment of Multiple Systematic Reviews (AMSTAR) tool. Article metadata and journal-related bibliometric indices were also obtained. Systematic reviews were classified as low (0-4), moderate (5-8) or high (9-11) quality. A prediction model for methodological quality was fitted using principal component and multivariate ordinal logistic regression analyses. We classified 220 studies as high (17·2%), moderate (55·0%) or low (27·8%) quality. Lower compliance rates were found for AMSTAR question (Q)5 (list of studies provided, 11·4%), Q10 (publication bias assessed, 27·7%), Q4 (status of publication included, 39·5%) and Q1 (a priori design provided, 40·9%). Factors such as meta-analysis inclusion [odds ratio (OR) 6·22; 95% confidence interval (CI) 2·78-14·86], funding by academic institutions (OR 2·90, 95% CI 1·11-7·89), Article Influence score (OR 2·14, 95% CI 1·05-6·67), 5-year impact factor (OR 1·34, 95% CI 1·02-1·40) and article page count (OR 1·08, 95% CI 1·02-1·15) significantly predicted higher quality. A high number of authors with a conflict of interest (OR 0·90, 95% CI 0·82-0·99) was significantly associated with lower quality. The methodological quality of systematic reviews published about psoriasis remains suboptimal. The type of funding sources and author conflicts may compromise study quality, increasing the risk of bias. © 2017 British Association of Dermatologists.

  14. Storm drains are sources of human fecal pollution during dry weather in three urban southern California watersheds.

    PubMed

    Sercu, Bram; Van De Werfhorst, Laurie C; Murray, Jill; Holden, Patricia A

    2009-01-15

    Coastal urbanized areas in Southern California experience frequent beach water quality warnings in summer due to high concentrations of fecal indicator bacteria (FIB). Remediation can be difficult, as sources are often unknown. During two summers, we sampled three urbanized watersheds in Santa Barbara, CA at sites with historically high FIB concentrations to determine if human fecal matter was influencing water quality. By quantification of a human-specific Bacteroides marker (HBM), human waste was evidenced throughout both transects, and concentrations were highest in the discharges of several flowing storm drains. The HBM concentrations in storm drain discharges varied by up to 5 orders of magnitude on the same day. While the exact points of entry into the storm drain systems were not definitively determined, further inspection of the drain infrastructure suggested exfiltrating sanitary sewers as possible sources. The HBM and FIB concentrations were not consistently correlated, although the exclusive occurrence of high HBM concentrations with high FIB concentrations warrants the use of FIB analyses for a first tier of sampling. The association of human fecal pollution with dry weather drainage could be a window into a larger problem for other urbanized coastal areas with Mediterranean-type climates.

  15. Wildlife, urban inputs, and landscape configuration are responsible for degraded swimming water quality at an embayed beach

    USGS Publications Warehouse

    Byappanahalli, Muruleedhara N.; Nevers, Meredith; Whitman, Richard L.; Ge, Zhongfu; Shively, Dawn A.; Spoljaric, Ashley; Przybyla-Kelly, Katarzyna

    2015-01-01

    Jeorse Park Beach, on southern Lake Michigan, experiences frequent closures due to high Escherichia coli (E. coli) levels since regular monitoring was implemented in 2005. During the summer of 2010, contaminant source tracking techniques, such as the conventional microbial and physical surveys and hydrodynamic models, were used to determine the reasons for poor water quality at Jeorse Park. Fecal indicator bacteria (E. coli, enterococci) were high throughout the season, with densities ranging from 12–2419 (culturable E. coli) and 1–2550 and < 1–5831 (culturable and qPCR enterococci, respectively). Genetic markers for human (Bacteroides HF183) and gull (Catellicoccus marimammalium) fecal contamination were found in 15% and 37% of the samples indicating multiple sources contributing to poor water quality. Nesting colonies of double-crested cormorants (Phalacrocorax auritus) have steadily increased since 2005, coinciding with high E. colilevels. A hydrodynamic model indicated that limited circulation allows bacteria entering the embayed area to be retained in nearshore areas; and bacterial resuspension from sand and stranded beach wrack during storm events compounds the problem. The integration of hydrodynamics, expanded use of chemical and biological markers, as well as more complex statistical multivariate techniques can improve microbial source tracking, informing management actions to improve recreational water quality. Alterations to embayed structures to improve circulation and reduce nuisance algae as well as growing native plants to retain sand to improve beach morphometry are among some of the restoration strategies under consideration in ongoing multi-agency collaborations.

  16. Resonant tunneling diodes as sources for millimeter and submillimeter wavelengths

    NASA Technical Reports Server (NTRS)

    Vanbesien, O.; Bouregba, R.; Mounaix, P.; Lippens, D.; Palmateer, L.; Pernot, J. C.; Beaudin, G.; Encrenaz, P.; Bockenhoff, E.; Nagle, J.

    1992-01-01

    High-quality Resonant Tunneling Diodes have been fabricated and tested as sources for millimeter and submillimeter wavelengths. The devices have shown excellent I-V characteristics with peak-to-valley current ratios as high as 6:1 and current densities in the range of 50-150 kA/cm(exp 2) at 300 K. Used as local oscillators, the diodes are capable of state of the art output power delivered by AlGaAs-based tunneling devices. As harmonic multipliers, a frequency of 320 GHz has been achieved by quintupling the fundamental oscillation of a klystron source.

  17. Can Sanitary Surveys Replace Water Quality Testing? Evidence from Kisii, Kenya

    PubMed Central

    Misati, Aaron Gichaba; Ogendi, George; Peletz, Rachel; Khush, Ranjiv; Kumpel, Emily

    2017-01-01

    Information about the quality of rural drinking water sources can be used to manage their safety and mitigate risks to health. Sanitary surveys, which are observational checklists to assess hazards present at water sources, are simpler to conduct than microbial tests. We assessed whether sanitary survey results were associated with measured indicator bacteria levels in rural drinking water sources in Kisii Central, Kenya. Overall, thermotolerant coliform (TTC) levels were high: all of the samples from the 20 tested dug wells, almost all (95%) of the samples from the 25 tested springs, and 61% of the samples from the 16 tested rainwater harvesting systems were contaminated with TTC. There were no significant associations between TTC levels and overall sanitary survey scores or their individual components. Contamination by TTC was associated with source type (dug wells and springs were more contaminated than rainwater systems). While sanitary surveys cannot be substituted for microbial water quality results in this context, they could be used to identify potential hazards and contribute to a comprehensive risk management approach. PMID:28178226

  18. Accessibility, nature and quality of health information on the Internet: a survey on osteoarthritis.

    PubMed

    Maloney, S; Ilic, D; Green, S

    2005-03-01

    This study aims to determine the quality and validity of information available on the Internet about osteoarthritis and to investigate the best way of sourcing this information. Keywords relevant to osteoarthritis were searched across 15 search engines representing medical, general and meta-search engines. Search engine efficiency was defined as the percentage of unique and relevant websites from all websites returned by each search engine. The quality of relevant information was appraised using the DISCERN tool and the concordance of the information offered by the website with the available evidence about osteoarthritis determined. A total of 3443 websites were retrieved, of which 344 were identified as unique and providing information relevant to osteoarthritis. The overall quality of website information was poor. There was no significant difference between types of search engine in sourcing relevant information; however, the information retrieved from medical search engines was of a higher quality. Fewer than a third of the websites identified as offering relevant information cited evidence to support their recommendations. Although the overall quality of website information about osteoarthritis was poor, medical search engines may provide consumers with the opportunity to source high-quality health information on the Internet. In the era of evidence-based medicine, one of the main obstacles to the Internet reaching its potential as a medical resource is the failure of websites to incorporate and attribute evidence-based information.

  19. Evaluation of flow quality in two large NASA wind tunnels at transonic speeds

    NASA Technical Reports Server (NTRS)

    Harvey, W. D.; Stainback, P. C.; Owen, F. K.

    1980-01-01

    Wind tunnel testing of low drag airfoils and basic transition studies at transonic speeds are designed to provide high quality aerodynamic data at high Reynolds numbers. This requires that the flow quality in facilities used for such research be excellent. To obtain a better understanding of the characteristics of facility disturbances and identification of their sources for possible facility modification, detailed flow quality measurements were made in two prospective NASA wind tunnels. Experimental results are presented of an extensive and systematic flow quality study of the settling chamber, test section, and diffuser in the Langley 8 foot transonic pressure tunnel and the Ames 12 foot pressure wind tunnel. Results indicate that the free stream velocity and pressure fluctuation levels in both facilities are low at subsonic speeds and are so high as to make it difficult to conduct meaningful boundary layer control and transition studies at transonic speeds.

  20. Gradient Magnitude Similarity Deviation: A Highly Efficient Perceptual Image Quality Index.

    PubMed

    Xue, Wufeng; Zhang, Lei; Mou, Xuanqin; Bovik, Alan C

    2014-02-01

    It is an important task to faithfully evaluate the perceptual quality of output images in many applications, such as image compression, image restoration, and multimedia streaming. A good image quality assessment (IQA) model should not only deliver high quality prediction accuracy, but also be computationally efficient. The efficiency of IQA metrics is becoming particularly important due to the increasing proliferation of high-volume visual data in high-speed networks. We present a new effective and efficient IQA model, called gradient magnitude similarity deviation (GMSD). The image gradients are sensitive to image distortions, while different local structures in a distorted image suffer different degrees of degradations. This motivates us to explore the use of global variation of gradient based local quality map for overall image quality prediction. We find that the pixel-wise gradient magnitude similarity (GMS) between the reference and distorted images combined with a novel pooling strategy-the standard deviation of the GMS map-can predict accurately perceptual image quality. The resulting GMSD algorithm is much faster than most state-of-the-art IQA methods, and delivers highly competitive prediction accuracy. MATLAB source code of GMSD can be downloaded at http://www4.comp.polyu.edu.hk/~cslzhang/IQA/GMSD/GMSD.htm.

  1. The impact of hybrid energy storage on power quality, when high power pulsed DC loads are operated on a microgrid testbed

    NASA Astrophysics Data System (ADS)

    Kelley, Jay Paul

    As the Navy's demands for high power transient loads evolves, so too does the need for alternative energy sources to back-up the more traditional power generation. Such applications in need of support include electrical grid backup and directed energy weapon systems such as electromagnetic launchers, laser systems, and high power microwave generators, among others. Among the alternative generation sources receiving considerable attention are energy storage devices such as rechargeable electrochemical batteries and capacitors. In such applications as those mentioned above, these energy storage devices offer the ability to serve a dual role as both a power source to the various loads as well high power loads themselves to the continual generation when the high power transient loads are in periods of downtime. With the recent developments in electrochemical energy storage, lithium-ion batteries (LIBs) seem like the obvious choice, but previous research has shown that the elevated rates of charging can be detrimental to both the cycle life and the operational life span of the device. In order to preserve the batteries, their charge rate must be limited. One proposed method to accomplish the dual role task mentioned above, while preserving the life of the batteries, is by combining high energy density LIBs with high power density electric double layer capacitors (EDLCs) or lithium-ion capacitors (LICs) using controllable power electronics to adjust the flow of power to and from each device. Such a configuration is typically referred to as hybrid energy storage module (HESM). While shipboard generators start up, the combined high energy density and high power density of the HESM provides the capability to source critical loads for an extended period of time at the high rates they demand. Once the generator is operationally efficient, the HESM can act as a high energy reservoir to harvest the energy from the generator while the loads are in short periods of inactivity. This enables the generator to maintain its operation at levels of high efficiency thereby increasing the power quality of the AC bus. The work discussed here is aimed at evaluating how the use of energy storage impacts the power quality on MicroGrid's AC bus when high rate DC and AC loads are sourced simultaneously. Also HESM has been developed and evaluated as a mean to optimizing both the power and energy density of the energy storage installed.

  2. Impacts by point and diffuse micropollutant sources on the stream water quality at catchment scale

    NASA Astrophysics Data System (ADS)

    Petersen, M. F.; Eriksson, E.; Binning, P. J.; Bjerg, P. L.

    2012-04-01

    The water quality of surface waters is threatened by multiple anthropogenic pollutants and the large variety of pollutants challenges the monitoring and assessment of the water quality. The aim of this study was to characterize and quantify both point and diffuse sources of micropollutants impacting the water quality of a stream at catchment scale. Grindsted stream in western Jutland, Denmark was used as a study site. The stream passes both urban and agricultural areas and is impacted by severe groundwater contamination in Grindsted city. Along a 12 km reach of Grindsted stream, the potential pollution sources were identified including a pharmaceutical factory site with a contaminated old drainage ditch, two waste deposits, a wastewater treatment plant, overflow structures, fish farms, industrial discharges and diffuse agricultural and urban sources. Six water samples were collected along the stream and analyzed for general water quality parameters, inorganic constituents, pesticides, sulfonamides, chlorinated solvents, BTEXs, and paracetamol and ibuprofen. The latter two groups were not detected. The general water quality showed typical conditions for a stream in western Jutland. Minor impacts by releases of organic matter and nutrients were found after the fish farms and the waste water treatment plant. Nickel was found at concentrations 5.8 - 8.8 μg/l. Nine pesticides and metabolites of both agricultural and urban use were detected along the stream; among these were the two most frequently detected and some rarely detected pesticides in Danish water courses. The concentrations were generally consistent with other findings in Danish streams and in the range 0.01 - 0.09 μg/l; except for metribuzin-diketo that showed high concentrations up to 0.74 μg/l. The groundwater contamination at the pharmaceutical factory site, the drainage ditch and the waste deposits is similar in composition containing among others sulfonamides and chlorinated solvents (including vinyl chloride). Vinyl chloride concentrations surpassed Danish stream water quality criteria with a factor 10. The largest chemical impact occurs at the reach downstream Grindsted city revealing that the main contaminant groundwater discharge zones are found here. The contaminant plume from the factory site north of the stream is known to impact the stream whereas the impact by the old landfill south of the stream remains to be assessed. A conceptual model of the chemical impacts by the identified sources was made, and high impact was assigned to the contaminant plume from the factory site and to the diffuse sources of urban-use and agricultural pesticides. The next step will be a quantification of the sources, which will be presented at the conference.

  3. TU-EF-204-02: Hiigh Quality and Sub-MSv Cerebral CT Perfusion Imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Ke; Niu, Kai; Wu, Yijing

    2015-06-15

    Purpose: CT Perfusion (CTP) imaging is of great importance in acute ischemic stroke management due to its potential to detect hypoperfused yet salvageable tissue and distinguish it from definitely unsalvageable tissue. However, current CTP imaging suffers from poor image quality and high radiation dose (up to 5 mSv). The purpose of this work was to demonstrate that technical innovations such as Prior Image Constrained Compressed Sensing (PICCS) have the potential to address these challenges and achieve high quality and sub-mSv CTP imaging. Methods: (1) A spatial-temporal 4D cascaded system model was developed to indentify the bottlenecks in the current CTPmore » technology; (2) A task-based framework was developed to optimize the CTP system parameters; (3) Guided by (1) and (2), PICCS was customized for the reconstruction of CTP source images. Digital anthropomorphic perfusion phantoms, animal studies, and preliminary human subject studies were used to validate and evaluate the potentials of using these innovations to advance the CTP technology. Results: The 4D cascaded model was validated in both phantom and canine stroke models. Based upon this cascaded model, it has been discovered that, as long as the spatial resolution and noise properties of the 4D source CT images are given, the 3D MTF and NPS of the final CTP maps can be analytically derived for a given set of processing methods and parameters. The cascaded model analysis also identified that the most critical technical factor in CTP is how to acquire and reconstruct high quality source images; it has very little to do with the denoising techniques often used after parametric perfusion calculations. This explained why PICCS resulted in a five-fold dose reduction or substantial improvement in image quality. Conclusion: Technical innovations generated promising results towards achieving high quality and sub-mSv CTP imaging for reliable and safe assessment of acute ischemic strokes. K. Li, K. Niu, Y. Wu: Nothing to disclose. G.-H. Chen: Research funded, GE Healthcare; Research funded, Siemens AX.« less

  4. Advanced X-ray Optics Metrology for Nanofocusing and Coherence Preservation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Goldberg, Kenneth A.; Yashchuk, Valeriy

    2007-12-01

    What is the point of developing new high-brightness light sources if beamline optics won't be available to realize the goals of nano-focusing and coherence preservation? That was one of the central questions raised during a workshop at the 2007 Advanced Light Source Users Meeting. Titled, 'Advanced X-Ray Optics Metrology for Nano-focusing and Coherence Preservation', the workshop was organized by Kenneth Goldberg and Valeriy Yashchuk (both of Lawrence Berkeley National Laboratory, LBNL), and it brought together industry representatives and researchers from Japan, Europe, and the US to discuss the state of the art and to outline the optics requirements of newmore » light sources. Many of the presentations are viewable on the workshop website http://goldberg.lbl.gov/MetrologyWorkshop07/. Many speakers shared the same view of one of the most significant challenges facing the development of new high-brightness third and fourth generation x-ray, soft x-ray, and EUV light sources: these sources place extremely high demands on the surface quality of beamline optics. In many cases, the 1-2-nm surface error specs that define the outer bounds of 'diffraction-limited' quality are beyond the reach of leading facilities and optics vendors. To focus light to 50-nm focal spots, or smaller, from reflective optics and to preserve the high coherent flux that new sources make possible, the optical surface quality and alignment tolerances must be measured in nano-meters and nano-radians. Without a significant, well-supported research effort, including the development of new metrology techniques for use both on and off the beamline, these goals will likely not be met. The scant attention this issue has garnered is evident in the stretched budgets and limited manpower currently dedicated to metrology. With many of the world's leading groups represented at the workshop, it became clear that Japan and Europe are several steps ahead of the US in this critical area. But the situation isn't all dire: several leading groups are blazing a trail forward, and the recognition of this issue is increasing. The workshop featured eleven invited talks whose presenters came from Japan, Europe, and the US.« less

  5. Temporal changes in the vertical distribution of flow and chloride in deep wells.

    PubMed

    Izbicki, John A; Christensen, Allen H; Newhouse, Mark W; Smith, Gregory A; Hanson, Randall T

    2005-01-01

    The combination of flowmeter and depth-dependent water-quality data was used to evaluate the quantity and source of high-chloride water yielded from different depths to eight production wells in the Pleasant Valley area of southern California. The wells were screened from 117 to 437 m below land surface, and in most cases, flow from the aquifer into the wells was not uniformly distributed throughout the well screen. Wells having as little as 6 m of screen in the overlying upper aquifer system yielded as much as 50% of their water from the upper system during drought periods, while the deeper parts of the well screens yielded 15% or less of the total yield of the wells. Mixing of water within wells during pumping degraded higher-quality water with poorer-quality water from deeper depths, and in some cases with poorer-quality water from the overlying upper aquifer system. Changes in the mixture of water within a well, resulting from changes in the distribution of flow into the well, changed the quality of water from the surface discharge of wells over time. The combination of flowmeter and depth-dependent water quality data yielded information about sources of high-chloride water to wells that was not available on the basis of samples collected from nearby observation wells. Changing well design to eliminate small quantities of poor-quality water from deeper parts of the well may improve the quality of water from some wells without greatly reducing well yield.

  6. Protein quality of insects as potential ingredients for dog and cat foods.

    PubMed

    Bosch, Guido; Zhang, Sheng; Oonincx, Dennis G A B; Hendriks, Wouter H

    2014-01-01

    Insects have been proposed as a high-quality, efficient and sustainable dietary protein source. The present study evaluated the protein quality of a selection of insect species. Insect substrates were housefly pupae, adult house cricket, yellow mealworm larvae, lesser mealworm larvae, Morio worm larvae, black soldier fly larvae and pupae, six spot roach, death's head cockroach and Argentinean cockroach. Reference substrates were poultry meat meal, fish meal and soyabean meal. Substrates were analysed for DM, N, crude fat, ash and amino acid (AA) contents and for in vitro digestibility of organic matter (OM) and N. The nutrient composition, AA scores as well as in vitro OM and N digestibility varied considerably between insect substrates. For the AA score, the first limiting AA for most substrates was the combined requirement for Met and Cys. The pupae of the housefly and black soldier fly were high in protein and had high AA scores but were less digestible than other insect substrates. The protein content and AA score of house crickets were high and similar to that of fish meal; however, in vitro N digestibility was higher. The cockroaches were relatively high in protein but the indispensable AA contents, AA scores and the in vitro digestibility values were relatively low. In addition to the indices of protein quality, other aspects such as efficiency of conversion of organic side streams, feasibility of mass-production, product safety and pet owner perception are important for future dog and cat food application of insects as alternative protein source.

  7. Experimental investigation on water quality standard of Yangtze River water source heat pump.

    PubMed

    Qin, Zenghu; Tong, Mingwei; Kun, Lin

    2012-01-01

    Due to the surface water in the upper reaches of Yangtze River in China containing large amounts of silt and algae, high content of microorganisms and suspended solids, the water in Yangtze River cannot be used for cooling a heat pump directly. In this paper, the possibility of using Yangtze River, which goes through Chongqing, a city in southwest China, as a heat source-sink was investigated. Water temperature and quality of the Yangtze River in the Chongqing area were analyzed and the performance of water source heat pump units in different sediment concentrations, turbidity and algae material conditions were tested experimentally, and the water quality standards, in particular surface water conditions, in the Yangtze River region that adapt to energy-efficient heat pumps were also proposed. The experimental results show that the coefficient of performance heat pump falls by 3.73% to the greatest extent, and the fouling resistance of cooling water in the heat exchanger increases up to 25.6% in different water conditions. When the sediment concentration and the turbidity in the river water are no more than 100 g/m3 and 50 NTU respectively, the performance of the heat pump is better, which can be used as a suitable river water quality standard for river water source heat pumps.

  8. Provision of safe domestic water for the promotion and protection of public health: a case study of the city of Beirut, Lebanon.

    PubMed

    Korfali, Samira Ibrahim; Jurdi, Mey

    2009-04-01

    Securing adequate safe drinking water and proper sanitation is a major challenge facing the developing world. The "Water for Life Decade" emphasizes the importance of upgrading national water quality and sanitation services. This study assessed the domestic water profile in the city of Beirut. Samples were collected from three types of household water sources (municipality, private wells, and vended water bottles) and assessed for their physiochemical and microbiological profile. At the same time, a cross-sectional survey assessing water consumption patterns and the prevalence of water-borne diseases was conducted. The results showed a deficient water quality profile in all three water sources. The measured physiochemical and bacteriological parameters reflected the high frequency of water-borne diseases. Action to secure a safe domestic water supply is essential. The plan should guarantee the protection of water sources, ensure sufficient treatment of domestic water and upgrade the national program for potable water quality control. Periodic quality monitoring and legislating the chaotic water-vending sector are indispensable. Additionally, the deterioration of private well sources by sea and wastewater infiltration necessitates the enforcement of legislation associated with the use and management of private wells. Consumer awareness and active contributions to promote and protect public health are important.

  9. 2-DE combined with two-layer feature selection accurately establishes the origin of oolong tea.

    PubMed

    Chien, Han-Ju; Chu, Yen-Wei; Chen, Chi-Wei; Juang, Yu-Min; Chien, Min-Wei; Liu, Chih-Wei; Wu, Chia-Chang; Tzen, Jason T C; Lai, Chien-Chen

    2016-11-15

    Taiwan is known for its high quality oolong tea. Because of high consumer demand, some tea manufactures mix lower quality leaves with genuine Taiwan oolong tea in order to increase profits. Robust scientific methods are, therefore, needed to verify the origin and quality of tea leaves. In this study, we investigated whether two-dimensional gel electrophoresis (2-DE) and nanoscale liquid chromatography/tandem mass spectroscopy (nano-LC/MS/MS) coupled with a two-layer feature selection mechanism comprising information gain attribute evaluation (IGAE) and support vector machine feature selection (SVM-FS) are useful in identifying characteristic proteins that can be used as markers of the original source of oolong tea. Samples in this study included oolong tea leaves from 23 different sources. We found that our method had an accuracy of 95.5% in correctly identifying the origin of the leaves. Overall, our method is a novel approach for determining the origin of oolong tea leaves. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Compatibility Grab Sampling and Analysis Plan for FY 2000

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    SASAKI, L.M.

    1999-12-29

    This sampling and analysis plan (SAP) identifies characterization objectives pertaining to sample collection, laboratory analytical evaluation, and reporting requirements for grab samples obtained to address waste compatibility. It is written in accordance with requirements identified in Data Quality Objectives for Tank Farms Waste Compatibility Program (Mulkey et al. 1999) and Tank Farm Waste Transfer Compatibility Program (Fowler 1999). In addition to analyses to support Compatibility, the Waste Feed Delivery program has requested that tank samples obtained for Compatibility also be analyzed to confirm the high-level waste and/or low-activity waste envelope(s) for the tank waste (Baldwin 1999). The analytical requirements tomore » confirm waste envelopes are identified in Data Quality Objectives for TWRS Privatization Phase I: Confirm Tank T is an Appropriate Feed Source for Low-Activity Waste Feed Batch X (Nguyen 1999a) and Data Quality Objectives for RPP Privatization Phase I: Confirm Tank T is an Appropriate Feed Source for High-Level Waste Feed Batch X (Nguyen 1999b).« less

  11. The National Audubon Society's eastern forest conservation initiative: examining opportunities for bird conservation at a regional scale

    Treesearch

    Curtis Smalling; Mary Elfner

    2010-01-01

    The forests of the east are under tremendous pressure from a variety of sources, including increasing development and fragmentation, declining air quality, declining water quality, and global climate change. Many priority bird species depend on these forested habitats, including a high percentage (75 percent) of neotropical migrant breeding species.

  12. Chemical vapor deposition of high T(sub c) superconducting films in a microgravity environment

    NASA Technical Reports Server (NTRS)

    Levy, Moises; Sarma, Bimal K.

    1994-01-01

    Since the discovery of the YBaCuO bulk materials in 1987, Metalorganic Chemical Vapor Deposition (MOCVD) has been proposed for preparing HTSC high T(sub c) films. This technique is now capable of producing high-T(sub c) superconducting thin films comparable in quality to those prepared by any other methods. The MOCVD technique has demonstrated its superior advantage in making large area high quality HTSC thin films and will play a major role in the advance of device applications of HTSC thin films. The organometallic precursors used in the MOCVD preparation of HTSC oxide thin films are most frequently metal beta-diketonates. High T(sub c) superconductors are multi-component oxides which require more than one component source, with each source, containing one kind of precursor. Because the volatility and stability of the precursors are strongly dependent on temperature, system pressure, and carrier gas flow rate, it has been difficult to control the gas phase composition, and hence film stoichiometry. In order circumvent these problems we have built and tested a single source MOCVD reactor in which a specially designed vaporizer was employed. This vaporizer can be used to volatilize a stoichiometric mixture of diketonates of yttrium, barium and copper to produce a mixed vapor in a 1:2:3 ratio respectively of the organometellics. This is accomplished even though the three compounds have significantly different volatilities. We have developed a model which provides insight into the process of vaporizing mixed precursors to produce high quality thin films of Y1Ba2Cu3O7. It shows that under steady state conditions the mixed organometallic vapor must have a stoichiometric ratio of the individual organometallics identical to that in the solid mixture.

  13. A Survey of Information Source Preferences of Parents of Individuals with Autism Spectrum Disorder

    ERIC Educational Resources Information Center

    Gibson, Amelia N.; Kaplan, Samantha; Vardell, Emily

    2017-01-01

    For parents of children with an Autism spectrum disorder (ASD), high quality, easily accessible information and a strong peer network can be the key to raising a happy, healthy child, and maintaining family well-being and emotional resilience. This article reports the findings of an anonymous survey examining the information source preferences for…

  14. A Study of the Effects of Outsourcing Residence Life Programs on Student Satisfaction

    ERIC Educational Resources Information Center

    Manley, James H., Jr.

    2011-01-01

    Institutions of higher education are facing the difficult challenge of meeting increased demands for high quality education and services for students, while keeping costs low, and finding new sources of revenue to compensate for the decrease in funding from state and federal sources. In an attempt to meet these demands new strategies and…

  15. Geology and ground-water resources of Outagamie County, Wisconsin

    USGS Publications Warehouse

    LeRoux, E.F.

    1957-01-01

    The ground water differs greatly in chemical quality from well to well, but it is generally a very hard calcium magnesium bicarbonate water, some of it high in iron. To aid in determining the source of well waters, 22 chemical analyses were plotted on a logarithmic diagram to obtain characteristic patterns for waters from several geologic sources.

  16. Identifications and Photometric Redshifts of the 2 Ms Chandra Deep Field-South Sources

    NASA Astrophysics Data System (ADS)

    Luo, B.; Brandt, W. N.; Xue, Y. Q.; Brusa, M.; Alexander, D. M.; Bauer, F. E.; Comastri, A.; Koekemoer, A.; Lehmer, B. D.; Mainieri, V.; Rafferty, D. A.; Schneider, D. P.; Silverman, J. D.; Vignali, C.

    2010-04-01

    We present reliable multiwavelength identifications and high-quality photometric redshifts for the 462 X-ray sources in the ≈2 Ms Chandra Deep Field-South (CDF-S) survey. Source identifications are carried out using deep optical-to-radio multiwavelength catalogs, and are then combined to create lists of primary and secondary counterparts for the X-ray sources. We identified reliable counterparts for 442 (95.7%) of the X-ray sources, with an expected false-match probability of ≈ 6.2%; we also selected four additional likely counterparts. The majority of the other 16 X-ray sources appear to be off-nuclear sources, sources associated with galaxy groups and clusters, high-redshift active galactic nuclei (AGNs), or spurious X-ray sources. A likelihood-ratio method is used for source matching, which effectively reduces the false-match probability at faint magnitudes compared to a simple error-circle matching method. We construct a master photometric catalog for the identified X-ray sources including up to 42 bands of UV-to-infrared data, and then calculate their photometric redshifts (photo-z's). High accuracy in the derived photo-z's is accomplished owing to (1) the up-to-date photometric data covering the full spectral energy distributions (SEDs) of the X-ray sources, (2) more accurate photometric data as a result of source deblending for ≈10% of the sources in the infrared bands and a few percent in the optical and near-infrared bands, (3) a set of 265 galaxy, AGN, and galaxy/AGN hybrid templates carefully constructed to best represent all possible SEDs, (4) the Zurich Extragalactic Bayesian Redshift Analyzer used to derive the photo-z's, which corrects the SED templates to best represent the SEDs of real sources at different redshifts and thus improves the photo-z quality. The reliability of the photo-z's is evaluated using the subsample of 220 sources with secure spectroscopic redshifts. We achieve an accuracy of |Δz|/(1 + z) ≈ 1% and an outlier [with |Δz|/(1 + z)>0.15] fraction of ≈1.4% for sources with spectroscopic redshifts. We performed blind tests to derive a more realistic estimate of the photo-z quality for sources without spectroscopic redshifts. We expect there are ≈9% outliers for the relatively brighter sources (R <~ 26), and the outlier fraction will increase to ≈15%-25% for the fainter sources (R >~ 26). The typical photo-z accuracy is ≈6%-7%. The outlier fraction and photo-z accuracy do not appear to have a redshift dependence (for z ≈ 0-4). These photo-z's appear to be the best obtained so far for faint X-ray sources, and they have been significantly (gsim50%) improved compared to previous estimates of the photo-z's for the X-ray sources in the ≈2 Ms Chandra Deep Field-North and ≈1 Ms CDF-S.

  17. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schüller, Andreas, E-mail: andreas.schueller@ptb.de; Meier, Markus; Selbach, Hans-Joachim

    Purpose: The aim of this study was to investigate whether a chamber-type-specific radiation quality correction factor k{sub Q} can be determined in order to measure the reference air kerma rate of {sup 60}Co high-dose-rate (HDR) brachytherapy sources with acceptable uncertainty by means of a well-type ionization chamber calibrated for {sup 192}Ir HDR sources. Methods: The calibration coefficients of 35 well-type ionization chambers of two different chamber types for radiation fields of {sup 60}Co and {sup 192}Ir HDR brachytherapy sources were determined experimentally. A radiation quality correction factor k{sub Q} was determined as the ratio of the calibration coefficients for {supmore » 60}Co and {sup 192}Ir. The dependence on chamber-to-chamber variations, source-to-source variations, and source strength was investigated. Results: For the PTW Tx33004 (Nucletron source dosimetry system (SDS)) well-type chamber, the type-specific radiation quality correction factor k{sub Q} is 1.19. Note that this value is valid for chambers with the serial number, SN ≥ 315 (Nucletron SDS SN ≥ 548) onward only. For the Standard Imaging HDR 1000 Plus well-type chambers, the type-specific correction factor k{sub Q} is 1.05. Both k{sub Q} values are independent of the source strengths in the complete clinically relevant range. The relative expanded uncertainty (k = 2) of k{sub Q} is U{sub k{sub Q}} = 2.1% for both chamber types. Conclusions: The calibration coefficient of a well-type chamber for radiation fields of {sup 60}Co HDR brachytherapy sources can be calculated from a given calibration coefficient for {sup 192}Ir radiation by using a chamber-type-specific radiation quality correction factor k{sub Q}. However, the uncertainty of a {sup 60}Co calibration coefficient calculated via k{sub Q} is at least twice as large as that for a direct calibration with a {sup 60}Co source.« less

  18. Local point sources that affect ground-water quality in the East Meadow area, Long Island, New York

    USGS Publications Warehouse

    Heisig, Paul M.

    1994-01-01

    The extent and chemical characteristics of ground water affected by three local point sources--a stormwater basin, uncovered road-salt-storage piles, and an abandoned sewage-treatment plant--were delineated during a 3-year study of the chemical characteristics and migration of a body of reclaimed wastewater that was applied to the watertable aquifer during recharge experiments from October 1982 through January 1984 in East Meadow. The timing, magnitude, and chemical quality of recharge from these point sources is highly variable, and all sources have the potential to skew determinations of the quality of ambient ground-water and of the reclaimed-wastewater plume if they are not taken into account. Ground water affected by recharge from the stormwater basin is characterized by low concentrations of nitrate + nitrite (less than 5 mg/L [milligrams per liter] as N) and sulfate (less than 40 mg/L) and is almost entirely within the upper glacial aquifer. The plume derived from road-salt piles is narrow, has high concentrations of chloride (greater than 50 mg/L) and sodium (greater than 75 mg/L), and also is limited to the upper glacial aquifer. The sodium, in high concentrations, could react with aquifer material and exchange for sorbed cations such as calcium, potassium, and magnesium. Water affected by secondary-treated sewage from the abandoned treatment plant extends 152 feet below land surface into the upper part of the Magothy aquifer and longitudinally beyond the southern edge of the study area, 7,750 feet south of the recharge site. Ground water affected by secondary-treated sewage within the study area typically contains elevated concentrations of reactive chemical constituents, such as potassium and ammonium, and low concentrations of dissolved oxygen. Conservative or minimally reactive constituents such as chloride and sodium have been transported out of the study area in the upper glacial aquifer and the intermediate (transitional) zone but remain in the less permeable upper part of the Magothy aquifer. Identification of the three point sources and delineation of their areas of influence improved definition of ambient ground-water quality and delineation of the reclaimed-wastewater plume.

  19. Urban Water Services in Fragile States: An Analysis of Drinking Water Sources and Quality in Port Harcourt, Nigeria, and Monrovia, Liberia.

    PubMed

    Kumpel, Emily; Albert, Jeff; Peletz, Rachel; de Waal, Dominick; Hirn, Maximilian; Danilenko, Alexander; Uhl, Vincent; Daw, Ashish; Khush, Ranjiv

    2016-07-06

    Establishing and maintaining public water services in fragile states is a significant development challenge. In anticipation of water infrastructure investments, this study compares drinking water sources and quality between Port Harcourt, Nigeria, and Monrovia, Liberia, two cities recovering from political and economic instability. In both cities, access to piped water is low, and residents rely on a range of other private and public water sources. In Port Harcourt, geographic points for sampling were randomly selected and stratified by population density, whereas in Monrovia, locations for sampling were selected from a current inventory of public water sources. In Port Harcourt, the sampling frame demonstrated extensive reliance on private boreholes and a preference, in both planned and unplanned settlements, for drinking bottled and sachet water. In Monrovia, sample collection focused on public sources (predominantly shallow dug wells). In Port Harcourt, fecal indicator bacteria (FIB) were detected in 25% of sources (N = 566), though concentrations were low. In Monrovia, 57% of sources contained FIB and 22% of sources had nitrate levels that exceeded standards (N = 204). In Monrovia, the convenience of piped water may promote acceptance of the associated water tariffs. However, in Port Harcourt, the high prevalence of self-supply and bottled and sachet drinking water suggests that the consumer's willingness to pay for ongoing municipal water supply improvements may be determined by service reliability and perceptions of water quality. © The American Society of Tropical Medicine and Hygiene.

  20. Urban Water Services in Fragile States: An Analysis of Drinking Water Sources and Quality in Port Harcourt, Nigeria, and Monrovia, Liberia

    PubMed Central

    Kumpel, Emily; Albert, Jeff; Peletz, Rachel; de Waal, Dominick; Hirn, Maximilian; Danilenko, Alexander; Uhl, Vincent; Daw, Ashish; Khush, Ranjiv

    2016-01-01

    Establishing and maintaining public water services in fragile states is a significant development challenge. In anticipation of water infrastructure investments, this study compares drinking water sources and quality between Port Harcourt, Nigeria, and Monrovia, Liberia, two cities recovering from political and economic instability. In both cities, access to piped water is low, and residents rely on a range of other private and public water sources. In Port Harcourt, geographic points for sampling were randomly selected and stratified by population density, whereas in Monrovia, locations for sampling were selected from a current inventory of public water sources. In Port Harcourt, the sampling frame demonstrated extensive reliance on private boreholes and a preference, in both planned and unplanned settlements, for drinking bottled and sachet water. In Monrovia, sample collection focused on public sources (predominantly shallow dug wells). In Port Harcourt, fecal indicator bacteria (FIB) were detected in 25% of sources (N = 566), though concentrations were low. In Monrovia, 57% of sources contained FIB and 22% of sources had nitrate levels that exceeded standards (N = 204). In Monrovia, the convenience of piped water may promote acceptance of the associated water tariffs. However, in Port Harcourt, the high prevalence of self-supply and bottled and sachet drinking water suggests that the consumer's willingness to pay for ongoing municipal water supply improvements may be determined by service reliability and perceptions of water quality. PMID:27114291

  1. Understanding the HighScope Approach: Early Years Education in Practice. Understanding the... Approach

    ERIC Educational Resources Information Center

    Wiltshire, Monica

    2011-01-01

    "Understanding the HighScope Approach" is a much needed source of information for those wishing to extend and consolidate their understanding of the HighScope Approach. It will enable the reader to analyse the essential elements of the HighScope Approach to early childhood and its relationship to quality early years practice. Exploring…

  2. Multi-copy entanglement purification with practical spontaneous parametric down conversion sources

    NASA Astrophysics Data System (ADS)

    Zhang, Shuai-Shuai; Shu, Qi; Zhou, Lan; Sheng, Yu-Bo

    2017-06-01

    Entanglement purification is to distill the high quality entanglement from the low quality entanglement with local operations and classical communications. It is one of the key technologies in long-distance quantum communication. We discuss an entanglement purification protocol (EPP) with spontaneous parametric down conversion (SPDC) sources, in contrast to previous EPP with multi-copy mixed states, which requires ideal entanglement sources. We show that the SPDC source is not an obstacle for purification, but can benefit the fidelity of the purified mixed state. This EPP works for linear optics and is feasible in current experiment technology. Project supported by the National Natural Science Foundation of China (Grant Nos. 11474168 and 61401222), the Natural Science Foundation of Jiangsu Province, China (Grant No. BK20151502), the Qing Lan Project in Jiangsu Province, China, and a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions, China.

  3. Signs of the Times: Sources of Professional Challenge and Sustenance for Veteran African American Teachers

    ERIC Educational Resources Information Center

    Richards, Dean D., IV

    2017-01-01

    Recruitment and retention of high-quality educators remains problematic throughout our public school systems. This is particularly so for teachers of minority-identifications and in high-poverty, high-minority urban schools and districts. Recent research concerning teacher longevity has typically focused on large-scale investigations of factors of…

  4. Quantifying Data Quality for Clinical Trials Using Electronic Data Capture

    PubMed Central

    Nahm, Meredith L.; Pieper, Carl F.; Cunningham, Maureen M.

    2008-01-01

    Background Historically, only partial assessments of data quality have been performed in clinical trials, for which the most common method of measuring database error rates has been to compare the case report form (CRF) to database entries and count discrepancies. Importantly, errors arising from medical record abstraction and transcription are rarely evaluated as part of such quality assessments. Electronic Data Capture (EDC) technology has had a further impact, as paper CRFs typically leveraged for quality measurement are not used in EDC processes. Methods and Principal Findings The National Institute on Drug Abuse Treatment Clinical Trials Network has developed, implemented, and evaluated methodology for holistically assessing data quality on EDC trials. We characterize the average source-to-database error rate (14.3 errors per 10,000 fields) for the first year of use of the new evaluation method. This error rate was significantly lower than the average of published error rates for source-to-database audits, and was similar to CRF-to-database error rates reported in the published literature. We attribute this largely to an absence of medical record abstraction on the trials we examined, and to an outpatient setting characterized by less acute patient conditions. Conclusions Historically, medical record abstraction is the most significant source of error by an order of magnitude, and should be measured and managed during the course of clinical trials. Source-to-database error rates are highly dependent on the amount of structured data collection in the clinical setting and on the complexity of the medical record, dependencies that should be considered when developing data quality benchmarks. PMID:18725958

  5. High-pitch Helical Dual-source Computed Tomographic Pulmonary Angiography: Comparing Image Quality in Inspiratory Breath-hold and During Free Breathing.

    PubMed

    Ajlan, Amr M; Binzaqr, Salma; Jadkarim, Dalia A; Jamjoom, Lamia G; Leipsic, Jonathon

    2016-01-01

    The purpose of this study was to compare qualitative and quantitative image parameters of dual-source high-pitch helical computed tomographic pulmonary angiography (CTPA) in breath-holding (BH) versus free-breathing (FB) patients. Ninety-nine consented patients (61 female individuals; mean age±SD, 49±18.7 y) were randomized into BH (n=45) versus FB (n=54) high-pitch helical CTPA. Patient characteristics and CTPA radiation doses were analyzed. Two readers assessed for pulmonary embolism (PE), transient interruption of contrast, and respiratory and cardiac motion. The readers used a subjective 3-point scale to rate the pulmonary artery opacification and lung parenchymal appearance. A single reader assessed mean pulmonary artery signal intensity, noise, contrast, signal to noise ratio, and contrast to noise ratio. PE was diagnosed in 16% BH and 19% FB patients. CTPAs of both groups were of excellent or acceptable quality for PE evaluation and of similar mean radiation doses (1.3 mSv). Transient interruption of contrast was seen in 5/45 (11%) BH and 5/54 (9%) FB patients (not statistically significant, P=0.54). No statistically significant difference was noted in cardiac, diaphragmatic, and lung parenchymal motion. Lung parenchymal assessment was excellent in all cases, except for 5/54 (9%) motion-affected FB cases with acceptable quality (statistically significant, P=0.03). No CTPA was considered nondiagnostic by any of the readers. No objective image quality differences were noted between both groups (P>0.05). High-pitch helical CTPA acquired during BH or in FB yields comparable image quality for the diagnosis of PE and lung pathology, with low radiation exposure. Only a modest increase in lung parenchymal artifacts is encountered in FB high-pitch helical CTPA.

  6. Scalable graphene production from ethanol decomposition by microwave argon plasma torch

    NASA Astrophysics Data System (ADS)

    Melero, C.; Rincón, R.; Muñoz, J.; Zhang, G.; Sun, S.; Perez, A.; Royuela, O.; González-Gago, C.; Calzada, M. D.

    2018-01-01

    A fast, efficient and simple method is presented for the production of high quality graphene on a large scale by using an atmospheric pressure plasma-based technique. This technique allows to obtain high quality graphene in powder in just one step, without the use of neither metal catalysts and nor specific substrate during the process. Moreover, the cost for graphene production is significantly reduced since the ethanol used as carbon source can be obtained from the fermentation of agricultural industries. The process provides an additional benefit contributing to the revalorization of waste in the production of a high-value added product like graphene. Thus, this work demonstrates the features of plasma technology as a low cost, efficient, clean and environmentally friendly route for production of high-quality graphene.

  7. Npr1 Ser/Thr Protein Kinase Links Nitrogen Source Quality and Carbon Availability with the Yeast Nitrate Transporter (Ynt1) Levels*

    PubMed Central

    Martín, Yusé; González, Yelvis V.; Cabrera, Elisa; Rodríguez, Celia; Siverio, José M.

    2011-01-01

    Ynt1, the single high affinity nitrate and nitrite transporter of the yeast Hansenula polymorpha, is regulated by the quality of nitrogen sources. Preferred nitrogen sources cause Ynt1 dephosphorylation, ubiquitinylation, endocytosis, and vacuolar degradation. In contrast, under nitrogen limitation Ynt1 is phosphorylated and sorted to the plasma membrane. We show here the involvement of the Ser/Thr kinase HpNpr1 in Ynt1 phosphorylation and regulation of Ynt1 levels in response to nitrogen source quality and the availability of carbon. In Δnpr1, Ynt1 phosphorylation does not take place, although Ynt1 ubiquitin conjugates increase. As a result, in this strain Ynt1 is sorted to the vacuole, from both plasma membrane and the later biosynthetic pathway in nitrogen-free conditions and nitrate. In contrast, overexpression of NPR1 blocks down-regulation of Ynt1, increasing Ynt1 phosphorylation at Ser-244 and -246 and reducing ubiquitinylation. Furthermore, Npr1 is phosphorylated in response to the preferred nitrogen sources, and indeed it is dephosphorylated in nitrogen-free medium. Under conditions where Npr1 is phosphorylated, Ynt1 is not and vice versa. We show for the first time that carbon starvation leads to Npr1 phosphorylation, whereas Ynt1 is dephosphorylated and degraded in the vacuole. Rapamycin prevents this, indicating a possible role of the target of rapamycin signaling pathway in this process. We concluded that Npr1 plays a key role in adapting Ynt1 levels to the nitrogen quality and availability of a source of carbon. PMID:21652715

  8. Analysis of Nonpoint-Source Ground-Water Contamination in Relation to Land Use: Assessment of Nonpoint-Source Contamination in Central Florida

    USGS Publications Warehouse

    German, Edward R.

    1996-01-01

    In central Florida, activities that might affect the quality of ground water include disposal of stormwater through drainage wells, citrus cultivation, and mining and processing of phosphate ore. Possible effects of these and other land-use activities include high concentrations of nitrogen compounds and the pesticide bromacil in the citrus area, and high concentrations of most of the major-dissolved constituents and some organic compounds in the mining area.

  9. Data Sources for an Environmental Quality Index: Availability, Quality, and Utility

    PubMed Central

    Rappazzo, Kristen; Messer, Lynne C.

    2011-01-01

    Objectives. An environmental quality index (EQI) for all counties in the United States is under development to explore the relationship between environmental insults and human health. The EQI is potentially useful for investigators researching health disparities to account for other concurrent environmental conditions. This article focused on the identification and assessment of data sources used in developing the EQI. Data source strengths, limitations, and utility were addressed. Methods. Five domains were identified that contribute to environmental quality: air, water, land, built, and sociodemographic environments. An inventory of possible data sources was created. Data sources were evaluated for appropriate spatial and temporal coverage and data quality. Results. The overall data inventory identified multiple data sources for each domain. From the inventory (187 sources, 617 records), the air, water, land, built environment, and sociodemographic domains retained 2, 9, 7, 4, and 2 data sources for inclusion in the EQI, respectively. However, differences in data quality, geographic coverage, and data availability existed between the domains. Conclusions. The data sources identified for use in the EQI may be useful to researchers, advocates, and communities to explore specific environmental quality questions. PMID:21836111

  10. Detection of spatial fluctuations of non-point source fecal pollution in coral reef surrounding waters in southwestern Puerto Rico using PCR-based assays.

    PubMed

    Bonkosky, M; Hernández-Delgado, E A; Sandoz, B; Robledo, I E; Norat-Ramírez, J; Mattei, H

    2009-01-01

    Human fecal contamination of coral reefs is a major cause of concern. Conventional methods used to monitor microbial water quality cannot be used to discriminate between different fecal pollution sources. Fecal coliforms, enterococci, and human-specific Bacteroides (HF183, HF134), general Bacteroides-Prevotella (GB32), and Clostridium coccoides group (CP) 16S rDNA PCR assays were used to test for the presence of non-point source fecal contamination across the southwestern Puerto Rico shelf. Inshore waters were highly turbid, consistently receiving fecal pollution from variable sources, and showing the highest frequency of positive molecular marker signals. Signals were also detected at offshore waters in compliance with existing microbiological quality regulations. Phylogenetic analysis showed that most isolates were of human fecal origin. The geographic extent of non-point source fecal pollution was large and impacted extensive coral reef systems. This could have deleterious long-term impacts on public health, local fisheries and in tourism potential if not adequately addressed.

  11. YouTube and food allergy: An appraisal of the educational quality of information.

    PubMed

    Reddy, Keerthi; Kearns, Mary; Alvarez-Arango, Santiago; Carrillo-Martin, Ismael; Cuervo-Pardo, Nathaly; Cuervo-Pardo, Lyda; Dimov, Ves; Lang, David M; Lopez-Alvarez, Sonia; Schroer, Brian; Mohan, Kaushik; Dula, Mark; Zheng, Simin; Kozinetz, Claudia; Gonzalez-Estrada, Alexei

    2018-06-01

    Food allergy affects an estimated 8% of children and 3% of adults in the United States. Food-allergic individuals increasingly use the web for medical information. We sought to determine the educational quality of food allergy YouTube videos. We performed a YouTube search using keywords "food allergy" and "food allergies". The 300 most viewed videos were included and analyzed for characteristics, source, and content. Source was further classified as healthcare provider, alternative medicine provider, patient, company, media, and professional society. A scoring system (FA-DQS) was created to evaluate quality (-10 to +34 points). Negative points were assigned for misleading information. Eight reviewers scored each video independently. Three hundred videos were analyzed, with a median of 6351.50 views, 19 likes, and 1 dislike. More video presenters were female (54.3%). The most common type of video source was alternative medicine provider (26.3%). Alternative treatments included the following: water fast, juicing, Ayurveda, apple cider, yoga, visualization, and sea moss. Controversial diagnostics included kinesiology, IgG testing, and pulse test. Almost half of the videos depicted a non-IgE-mediated reaction (49.0%).Videos by professional societies had the highest FA-DQS (7.27). Scores for videos by professional societies were significantly different from other sources (P < .001). There was a high degree of agreement among reviewers (ICC = 0.820; P < .001). YouTube videos on food allergy frequently recommend controversial diagnostics and commonly depict non-IgE-mediated reactions. There is a need for high-quality, evidence-based, educational videos on food allergy. © 2018 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

  12. Francis E. Walter Dam and Reservoir Project, Water Quality Data Report (RCS-DAEN-CWE-15).

    DTIC Science & Technology

    1980-12-01

    downstream, as well as within, the lake. Analysis of these samples rives an understanding of the effect of the lake on water quality: • . The...regulation, are available for analysis . Water quality data;I (temperature, dissolved oxygen, conductivity, pH, phosphorous, total dissolved solids...depresses the pH following a rain storm. If the source of tre acid water is Fhallow lakes and swamps~lignin and tannin concentrations would be high

  13. 45 CFR 1388.1 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... resources and funding sources, and their institutional history. These factors converge to create a network.... State-of-the-art means that UAP activities are of high quality (using the latest technology), worthy of...

  14. Microbial and geochemical quality of shallow well water in high-density areas in Mzuzu City in Malawi

    NASA Astrophysics Data System (ADS)

    Msilimba, Golden; Wanda, Elijah M. M.

    In Malawi, shallow wells constitute the most important water sources for domestic purposes. However, increasing human population coupled with poor sanitation and infrastructure is undermining the quality of shallow well water. An assessment of microbial and geochemical quality of shallow well water in high-density areas of Zolozolo, Ching’ambo and Chiputula in Mzuzu City, Northern Malawi, has been carried out. The study aimed at characterising domestic water sources, identifying possible sources of water contamination and determining levels of microbial and chemical contamination. Arc-view GIS was used to map the water sources. A questionnaire survey was carried out to elicit information on characteristics of drinking water sources. Water samples were collected from quasi-randomly selected shallow wells and analysed for microbial and chemical parameters using standard methods. HCA, performed using R-programme, was used to group sampled sites according to their bio-physicochemical characteristics. Compliance of the water with MBS/WHO water quality guidelines was determined. The WQI was computed to turn multifaceted data obtained from laboratory analyses into simple information that is comprehensible and useable by the public to assess overall quality of water at a specific water points. The GW-chart was used to show hydrogeochemical water types from each sampled site. Microbial analysis revealed that water from 96.3% of shallow wells recorded faecal coliforms ranging from 129 to 920 cfu per 100 ml which were significantly higher than the Malawi Standards and WHO thresholds. In general, shallow well water is of low mineralisation (EC range 80-500 μS cm-1), with hydrogeochemical facies dominated by Ca-HCO3, which evolves to Ca-Cl water type. The shallow well water registered a WQI range of 50.16-66.04%, with a medium WQ rating. This suggested that the water obtained from the shallow wells is unsuitable for direct human consumption. It was observed that 100% of the shallow wells were at risk of pollution from onsite sanitation because of their proximity to sanitary facilities. It was strongly recommended that onsite treatment interventions have to be mobilised and initiated to protect the households from further possible consequences of using the water.

  15. Groundwater quality in the Northern Atlantic Coastal Plain aquifer system, eastern United States

    USGS Publications Warehouse

    Lindsey, Bruce; Belitz, Kenneth

    2017-01-19

    Groundwater provides nearly 50 percent of the Nation’s drinking water. To help protect this vital resource, the U.S. Geological Survey (USGS) National Water-Quality Assessment (NAWQA) Project assesses groundwater quality in aquifers that are important sources of drinking water. The Northern Atlantic Coastal Plain aquifer system constitutes one of the important areas being evaluated. One or more inorganic constituents with human-health benchmarks were detected at high concentrations in about 15 percent of the study area and at moderate concentrations in about 17 percent. Organic constituents were not detected at high concentrations in the study area.

  16. Groundwater quality in the Coastal Lowlands aquifer system, south-central United States

    USGS Publications Warehouse

    Barlow, Jeannie R.B.; Belitz, Kenneth

    2017-01-19

    Groundwater provides nearly 50 percent of the Nation’s drinking water. To help protect this vital resource, the U.S. Geological Survey (USGS) National Water-Quality Assessment (NAWQA) Project assesses groundwater quality in aquifers that are important sources of drinking water. The Coastal Lowlands aquifer system constitutes one of the important areas being evaluated. One or more inorganic constituents with human-health benchmarks were detected at high concentrations in about 12 percent of the study area and at moderate concentrations in about 18 percent. Organic constituents were not detected at high or moderate concentrations in the study area.

  17. Information Expensiveness Perceived by Vietnamese Patients with Respect to Healthcare Provider’s Choice

    PubMed Central

    Quan-Hoang, Vuong

    2016-01-01

    Background: Patients have to acquire information to support their decision on choosing a suitable healthcare provider. But in developing countries like Vietnam, accessibility issues remain an obstacle, thus adversely affect both quality and costliness of healthcare information. Vietnamese use both sources from health professionals and friends/relatives, especially when quality of the Internet-based cheaper sources appear to be still questionable. The search of information from both professionals and friends/relatives incurs some cost, which can be viewed as low or high depending low or high accessibility to the sources. These views potentially affect their choices. Aim and Objectives: To investigate the effects that medical/health services information on perceived expensiveness of patients’ labor costs. Two related objectives are a) establishing empirical relations between accessibility to sources and expensiveness; and, b) probabilistic trends of probabilities for perceived expensiveness. Results: There is evidence for established relations among the variables “Convexp” and “Convrel” (all p’s < 0.01), indicating that both information sources (experts and friends/relatives) have influence on patients perception of information expensiveness. The use of experts source tends to increase the probability of perceived expensiveness. Conclusion: a) Probabilistic trends show Vietnamese patients have propensity to value healthcare information highly and do not see it as “expensive”; b) The majority of Vietnamese households still take non-professional advices at their own risks; c) There is more for the public healthcare information system to do to reduce costliness and risk of information. The Internet-based health service users communities cannot replace this system. PMID:28077894

  18. Soil heavy metal pollution and risk assessment associated with the Zn-Pb mining region in Yunnan, Southwest China.

    PubMed

    Cheng, Xianfeng; Danek, Tomas; Drozdova, Jarmila; Huang, Qianrui; Qi, Wufu; Zou, Liling; Yang, Shuran; Zhao, Xinliang; Xiang, Yungang

    2018-03-07

    The environmental assessment and identification of sources of heavy metals in Zn-Pb ore deposits are important steps for the effective prevention of subsequent contamination and for the development of corrective measures. The concentrations of eight heavy metals (As, Cd, Cr, Cu, Hg, Ni, Pb, and Zn) in soils from 40 sampling points around the Jinding Zn-Pb mine in Yunnan, China, were analyzed. An environmental quality assessment of the obtained data was performed using five different contamination and pollution indexes. Statistical analyses were performed to identify the relations among the heavy metals and the pH in soils and possible sources of pollution. The concentrations of As, Cd, Pb, and Zn were extremely high, and 23, 95, 25, and 35% of the samples, respectively, exceeded the heavy metal limits set in the Chinese Environmental Quality Standard for Soils (GB15618-1995, grade III). According to the contamination and pollution indexes, environmental risks in the area are high or extremely high. The highest risk is represented by Cd contamination, the median concentration of which exceeds the GB15618-1995 limit. Based on the combination of statistical analyses and geostatistical mapping, we identified three groups of heavy metals that originate from different sources. The main sources of As, Cd, Pb, Zn, and Cu are mining activities, airborne particulates from smelters, and the weathering of tailings. The main sources of Hg are dust fallout and gaseous emissions from smelters and tailing dams. Cr and Ni originate from lithogenic sources.

  19. In silico carbon molecular beam epitaxial growth of graphene on the h-BN substrate: carbon source effect on van der Waals epitaxy

    NASA Astrophysics Data System (ADS)

    Lee, Jonghoon; Varshney, Vikas; Park, Jeongho; Farmer, Barry L.; Roy, Ajit K.

    2016-05-01

    Against the presumption that hexagonal boron-nitride (h-BN) should provide an ideal substrate for van der Waals (vdW) epitaxy to grow high quality graphene films, carbon molecular beam epitaxy (CMBE) techniques using solid carbon sublimation have reported relatively poor quality of the graphene. In this article, the CMBE growth of graphene on the h-BN substrate is numerically studied in order to identify the effect of the carbon source on the quality of the graphene film. The carbon molecular beam generated by the sublimation of solid carbon source materials such as graphite and glassy carbon is mostly composed of atomic carbon, carbon dimers and carbon trimers. Therefore, the graphene film growth becomes a complex process involving various deposition characteristics of a multitude of carbon entities. Based on the study of surface adsorption and film growth characteristics of these three major carbon entities comprising graphite vapour, we report that carbon trimers convey strong traits of vdW epitaxy prone to high quality graphene growth, while atomic carbon deposition is a surface-reaction limited process accompanied by strong chemisorption. The vdW epitaxial behaviour of carbon trimers is found to be substantial enough to nucleate and develop into graphene like planar films within a nanosecond of high flux growth simulation, while reactive atomic carbons tend to impair the structural integrity of the crystalline h-BN substrate upon deposition to form an amorphous interface between the substrate and the growing carbon film. The content of reactive atomic carbons in the molecular beam is suspected to be the primary cause of low quality graphene reported in the literature. A possible optimization of the molecular beam composition towards the synthesis of better quality graphene films is suggested.Against the presumption that hexagonal boron-nitride (h-BN) should provide an ideal substrate for van der Waals (vdW) epitaxy to grow high quality graphene films, carbon molecular beam epitaxy (CMBE) techniques using solid carbon sublimation have reported relatively poor quality of the graphene. In this article, the CMBE growth of graphene on the h-BN substrate is numerically studied in order to identify the effect of the carbon source on the quality of the graphene film. The carbon molecular beam generated by the sublimation of solid carbon source materials such as graphite and glassy carbon is mostly composed of atomic carbon, carbon dimers and carbon trimers. Therefore, the graphene film growth becomes a complex process involving various deposition characteristics of a multitude of carbon entities. Based on the study of surface adsorption and film growth characteristics of these three major carbon entities comprising graphite vapour, we report that carbon trimers convey strong traits of vdW epitaxy prone to high quality graphene growth, while atomic carbon deposition is a surface-reaction limited process accompanied by strong chemisorption. The vdW epitaxial behaviour of carbon trimers is found to be substantial enough to nucleate and develop into graphene like planar films within a nanosecond of high flux growth simulation, while reactive atomic carbons tend to impair the structural integrity of the crystalline h-BN substrate upon deposition to form an amorphous interface between the substrate and the growing carbon film. The content of reactive atomic carbons in the molecular beam is suspected to be the primary cause of low quality graphene reported in the literature. A possible optimization of the molecular beam composition towards the synthesis of better quality graphene films is suggested. Electronic supplementary information (ESI) available: Three movie files: 3mer-physorption.mpg and 3mer-chemisorption.mpg feature examples of the adsorption state sampling of a carbon trimer on the heated h-BN substrate as mentioned in the ``Single Molecule Adsorption Study'' section. In 3mer-film-growth.mpg, an instance of honey comb formation during the initial phase of graphene growth simulation using a carbon trimer beam is captured. An initially sp hybridized carbon atom (red colored) becomes sp2 hybridized as a result of additional covalent bonding with the impinging carbon trimer. As the bond angle around the red carbon changes from 180 degree (sp) to 120 degree (sp2), nearby carbon atoms enclose to form a hexagon structure composed of 6 carbon atoms. See DOI: 10.1039/c6nr01396a

  20. Bacteriological and physico-chemical quality of drinking water sources in a rural community of Ethiopia.

    PubMed

    Tsega, N; Sahile, S; Kibret, M; Abera, B

    2013-12-01

    Accesses to safe water is a universal need however, many of the world's population lack access to adequate and safe water. Consumption of water contaminated causes health risk to the public and the situation is serous in rural areas. To assess the bacteriological and physico-chemical quality of drinking water sources in a rural community of Ethiopia. Water samples were collected from tap, open springs, open dug wells and protected springs for bacteriological analysis of total coliforms and thermotolerant coliforms. The turbidity, pH and temperature were measured immediately after collection. Most drinking water sources were found to have coliform counts above the recommended national and international guidelines and had high sanitary risk scores. There was a statistically significant difference among water sources with respect to TC and TTC (p < 0.05) and there was a statistically significant positive correlation between coliform counts and sanitary risk scores (p < 0.01). Most water sources didn't satisfy the turbidity values recommended by WHO. The water sources were heavily contaminated which suggested poor protection and sanitation practice in the water sources. Source protection strategies as well as monitoring are recommend for this community.

  1. Funding Source and Research Report Quality in Nutrition Practice-Related Research

    PubMed Central

    Myers, Esther F.; Parrott, J. Scott; Cummins, Deborah S.; Splett, Patricia

    2011-01-01

    Background The source of funding is one of many possible causes of bias in scientific research. One method of detecting potential for bias is to evaluate the quality of research reports. Research exploring the relationship between funding source and nutrition-related research report quality is limited and in other disciplines the findings are mixed. Objective The purpose of this study is to determine whether types of funding sources of nutrition research are associated with differences in research report quality. Design A retrospective study of research reporting quality, research design and funding source was conducted on 2539 peer reviewed research articles from the American Dietetic Association's Evidence Analysis Library® database. Results Quality rating frequency distributions indicate 43.3% of research reports were rated as positive, 50.1% neutral, and 6.6% as negative. Multinomial logistic regression results showed that while both funding source and type of research design are significant predictors of quality ratings (χ2 = 118.99, p<0.001), the model's usefulness in predicting overall research report quality is little better than chance. Compared to research reports with government funding, those not acknowledging any funding sources, followed by studies with University/hospital funding were more likely to receive neutral vs positive quality ratings, OR = 1.85, P <0.001 and OR = 1.54, P<0.001, respectively and those that did not report funding were more likely to receive negative quality ratings (OR = 4.97, P<0.001). After controlling for research design, industry funded research reports were no more likely to receive a neutral or negative quality rating than those funded by government sources. Conclusion Research report quality cannot be accurately predicted from the funding source after controlling for research design. Continued vigilance to evaluate the quality of all research regardless of the funding source and to further understand other factors that affect quality ratings are warranted. PMID:22163017

  2. Funding source and research report quality in nutrition practice-related research.

    PubMed

    Myers, Esther F; Parrott, J Scott; Cummins, Deborah S; Splett, Patricia

    2011-01-01

    The source of funding is one of many possible causes of bias in scientific research. One method of detecting potential for bias is to evaluate the quality of research reports. Research exploring the relationship between funding source and nutrition-related research report quality is limited and in other disciplines the findings are mixed. The purpose of this study is to determine whether types of funding sources of nutrition research are associated with differences in research report quality. A retrospective study of research reporting quality, research design and funding source was conducted on 2539 peer reviewed research articles from the American Dietetic Association's Evidence Analysis Library® database. Quality rating frequency distributions indicate 43.3% of research reports were rated as positive, 50.1% neutral, and 6.6% as negative. Multinomial logistic regression results showed that while both funding source and type of research design are significant predictors of quality ratings (χ2 = 118.99, p≤0.001), the model's usefulness in predicting overall research report quality is little better than chance. Compared to research reports with government funding, those not acknowledging any funding sources, followed by studies with University/hospital funding were more likely to receive neutral vs positive quality ratings, OR = 1.85, P <0.001 and OR = 1.54, P<0.001, respectively and those that did not report funding were more likely to receive negative quality ratings (OR = 4.97, P<0.001). After controlling for research design, industry funded research reports were no more likely to receive a neutral or negative quality rating than those funded by government sources. Research report quality cannot be accurately predicted from the funding source after controlling for research design. Continued vigilance to evaluate the quality of all research regardless of the funding source and to further understand other factors that affect quality ratings are warranted.

  3. Evaluating Air-Quality Models: Review and Outlook.

    NASA Astrophysics Data System (ADS)

    Weil, J. C.; Sykes, R. I.; Venkatram, A.

    1992-10-01

    Over the past decade, much attention has been devoted to the evaluation of air-quality models with emphasis on model performance in predicting the high concentrations that are important in air-quality regulations. This paper stems from our belief that this practice needs to be expanded to 1) evaluate model physics and 2) deal with the large natural or stochastic variability in concentration. The variability is represented by the root-mean- square fluctuating concentration (c about the mean concentration (C) over an ensemble-a given set of meteorological, source, etc. conditions. Most air-quality models used in applications predict C, whereas observations are individual realizations drawn from an ensemble. For cC large residuals exist between predicted and observed concentrations, which confuse model evaluations.This paper addresses ways of evaluating model physics in light of the large c the focus is on elevated point-source models. Evaluation of model physics requires the separation of the mean model error-the difference between the predicted and observed C-from the natural variability. A residual analysis is shown to be an elective way of doing this. Several examples demonstrate the usefulness of residuals as well as correlation analyses and laboratory data in judging model physics.In general, c models and predictions of the probability distribution of the fluctuating concentration (c), (c, are in the developmental stage, with laboratory data playing an important role. Laboratory data from point-source plumes in a convection tank show that (c approximates a self-similar distribution along the plume center plane, a useful result in a residual analysis. At pmsent,there is one model-ARAP-that predicts C, c, and (c for point-source plumes. This model is more computationally demanding than other dispersion models (for C only) and must be demonstrated as a practical tool. However, it predicts an important quantity for applications- the uncertainty in the very high and infrequent concentrations. The uncertainty is large and is needed in evaluating operational performance and in predicting the attainment of air-quality standards.

  4. Near-infrared supercontinuum laser beam source in the second and third near-infrared optical windows used to image more deeply through thick tissue as compared with images from a lamp source

    NASA Astrophysics Data System (ADS)

    Sordillo, Laura A.; Lindwasser, Lukas; Budansky, Yury; Leproux, Philippe; Alfano, Robert R.

    2015-03-01

    With the use of longer near-infrared (NIR) wavelengths, image quality can be increased due to less scattering (described by the inverse wavelength power dependence 1/λn where n≥1) and minimal absorption from water molecules. Longer NIR windows, known as the second (1100 nm to 1350 nm) and third (1600 to 1870 nm) NIR windows are utilized to penetrate more deeply into tissue media and produce high-quality images. An NIR supercontinuum (SC) laser light source, with wavelengths in the second and third NIR optical windows to image tissue provides ballistic imaging of tissue. The SC ballistic beam can penetrate depths of up to 10 mm through tissue.

  5. Geochemistry of dissolved trace elements and heavy metals in the Dan River Drainage (China): distribution, sources, and water quality assessment.

    PubMed

    Meng, Qingpeng; Zhang, Jing; Zhang, Zhaoyu; Wu, Tairan

    2016-04-01

    Dissolved trace elements and heavy metals in the Dan River drainage basin, which is the drinking water source area of South-to-North Water Transfer Project (China), affect large numbers of people and should therefore be carefully monitored. To investigate the distribution, sources, and quality of river water, this study integrating catchment geology and multivariate statistical techniques was carried out in the Dan River drainage from 99 river water samples collected in 2013. The distribution of trace metal concentrations in the Dan River drainage was similar to that in the Danjiangkou Reservoir, indicating that the reservoir was significantly affected by the Dan River drainage. Moreover, our results suggested that As, Sb, Cd, Mn, and Ni were the major pollutants. We revealed extremely high concentrations of As and Sb in the Laoguan River, Cd in the Qingyou River, Mn, Ni, and Cd in the Yinhua River, As and Sb in the Laojun River, and Sb in the Dan River. According to the water quality index, water in the Dan River drainage was suitable for drinking; however, an exposure risk assessment model suggests that As and Sb in the Laojun and Laoguan rivers could pose a high risk to humans in terms of adverse health and potential non-carcinogenic effects.

  6. Assessment of aggregate sources in Michigan for high speed railroad ballast.

    DOT National Transportation Integrated Search

    2014-01-01

    MDOT purchased 135 miles of the Norfolk-Southern railroad in 2012 to upgrade for high speed rail travel : between Chicago and the Detroit area. An important part of the upgrade is to assess the current quality of : the ballast material and to determi...

  7. Quality Control for Ambient Sampling of PCDD/PCDF from Open Combustion Sources

    EPA Science Inventory

    Both long duration (> 6 h) and high temperature (up to 139o C) sampling efforts were conducted using ambient air sampling methods to determine if either high volume throughput or higher than ambient sampling temperatures resulted in loss of target polychlorinated dibenzodioxins/d...

  8. Value Added Processing of Aflatoxin Contaminated Peanut Meal

    USDA-ARS?s Scientific Manuscript database

    Peanut meal (PM) is the solid material remaining after commercial extraction of oil. Despite being an excellent source of high quality protein, applications of PM are limited to feed markets as this material typically contains high concentrations of aflatoxin. Our research group has developed a nov...

  9. Quality of Best Possible Medication History upon Admission to Hospital: Comparison of Nurses and Pharmacy Students and Consideration of National Quality Indicators.

    PubMed

    Sproul, Ashley; Goodine, Carole; Moore, David; McLeod, Amy; Gordon, Jacqueline; Digby, Jennifer; Stoica, George

    2018-01-01

    Medication reconciliation at transitions of care increases patient safety. Collection of an accurate best possible medication history (BPMH) on admission is a key step. National quality indicators are used as surrogate markers for BPMH quality, but no literature on their accuracy exists. Obtaining a high-quality BPMH is often labour- and resource-intensive. Pharmacy students are now being assigned to obtain BPMHs, as a cost-effective means to increase BPMH completion, despite limited information to support the quality of BPMHs obtained by students relative to other health care professionals. To determine whether the national quality indicator of using more than one source to complete a BPMH is a true marker of quality and to assess whether BPMHs obtained by pharmacy students were of quality equal to those obtained by nurses. This prospective trial compared BPMHs for the same group of patients collected by nurses and by trained pharmacy students in the emergency departments of 2 sites within a large health network over a 2-month period (July and August 2016). Discrepancies between the 2 versions were identified by a pharmacist, who determined which party (nurse, pharmacy student, or both) had made an error. A panel of experts reviewed the errors and ranked their severity. BPMHs were prepared for a total of 40 patients. Those prepared by nurses were more likely to contain an error than those prepared by pharmacy students (171 versus 43 errors, p = 0.006). There was a nonsignificant trend toward less severe errors in BPMHs completed by pharmacy students. There was no significant difference in the mean number of errors in relation to the specified quality indicator (mean of 2.7 errors for BPMHs prepared from 1 source versus 4.8 errors for BPMHs prepared from ≥ 2 sources, p = 0.08). The surrogate marker (number of BPMH sources) may not reflect BPMH quality. However, it appears that BPMHs prepared by pharmacy students had fewer errors and were of similar quality (in terms of clinically significant errors) relative to those prepared by nurses.

  10. Farmers, Trust, and the Market Solution to Water Pollution: The Role of Social Embeddedness in Water Quality Trading

    ERIC Educational Resources Information Center

    Mariola, Matt J.

    2012-01-01

    Water quality trading (WQT) is a market arrangement in which a point-source water polluter pays farmers to implement conservation practices and claims the resulting benefits as credits toward meeting a pollution permit. Success rates of WQT programs nationwide are highly variable. Most of the literature on WQT is from an economic perspective…

  11. Factors controlling groundwater quality in the Yeonjegu District of Busan City, Korea, using the hydrogeochemical processes and fuzzy GIS.

    PubMed

    Venkatramanan, Senapathi; Chung, Sang Yong; Selvam, Sekar; Lee, Seung Yeop; Elzain, Hussam Eldin

    2017-10-01

    The hydrogeochemical processes and fuzzy GIS techniques were used to evaluate the groundwater quality in the Yeonjegu district of Busan Metropolitan City, Korea. The highest concentrations of major ions were mainly related to the local geology. The seawater intrusion into the river water and municipal contaminants were secondary contamination sources of groundwater in the study area. Factor analysis represented the contamination sources of the mineral dissolution of the host rocks and domestic influences. The Gibbs plot exhibited that the major ions were derived from the rock weathering condition. Piper's trilinear diagram showed that the groundwater quality was classified into five types of CaHCO 3 , NaHCO 3 , NaCl, CaCl 2 , and CaSO 4 types in that order. The ionic relationship and the saturation mineral index of the ions indicated that the evaporation, dissolution, and precipitation processes controlled the groundwater chemistry. The fuzzy GIS map showed that highly contaminated groundwater occurred in the northeastern and the central parts and that the groundwater of medium quality appeared in most parts of the study area. It suggested that the groundwater quality of the study area was influenced by local geology, seawater intrusion, and municipal contaminants. This research clearly demonstrated that the geochemical analyses and fuzzy GIS method were very useful to identify the contaminant sources and the location of good groundwater quality.

  12. Sensitivity of stream water age to climatic variability and land use change: implications for water quality

    NASA Astrophysics Data System (ADS)

    Soulsby, Chris; Birkel, Christian; Geris, Josie; Tetzlaff, Doerthe

    2016-04-01

    Advances in the use of hydrological tracers and their integration into rainfall runoff models is facilitating improved quantification of stream water age distributions. This is of fundamental importance to understanding water quality dynamics over both short- and long-time scales, particularly as water quality parameters are often associated with water sources of markedly different ages. For example, legacy nitrate pollution may reflect deeper waters that have resided in catchments for decades, whilst more dynamics parameters from anthropogenic sources (e.g. P, pathogens etc) are mobilised by very young (<1 day) near-surface water sources. It is increasingly recognised that water age distributions of stream water is non-stationary in both the short (i.e. event dynamics) and longer-term (i.e. in relation to hydroclimatic variability). This provides a crucial context for interpreting water quality time series. Here, we will use longer-term (>5 year), high resolution (daily) isotope time series in modelling studies for different catchments to show how variable stream water age distributions can be a result of hydroclimatic variability and the implications for understanding water quality. We will also use examples from catchments undergoing rapid urbanisation, how the resulting age distributions of stream water change in a predictable way as a result of modified flow paths. The implication for the management of water quality in urban catchments will be discussed.

  13. Model assessment of atmospheric pollution control schemes for critical emission regions

    NASA Astrophysics Data System (ADS)

    Zhai, Shixian; An, Xingqin; Liu, Zhao; Sun, Zhaobin; Hou, Qing

    2016-01-01

    In recent years, the atmospheric environment in portions of China has become significantly degraded and the need for emission controls has become urgent. Because more international events are being planned, it is important to implement air quality assurance targeted at significant events held over specific periods of time. This study sets Yanqihu (YQH), Beijing, the location of the 2014 Beijing APEC (Asia-Pacific Economic Cooperation) summit, as the target region. By using the atmospheric inversion model FLEXPART, we determined the sensitive source zones that had the greatest impact on the air quality of the YQH region in November 2012. We then used the air-quality model Models-3/CMAQ and a high-resolution emissions inventory of the Beijing-Tianjian-Hebei region to establish emission reduction tests for the entire source area and for specific sensitive source zones. This was achieved by initiating emission reduction schemes at different ratios and different times. The results showed that initiating a moderate reduction of emissions days prior to a potential event is more beneficial to the air quality of Beijing than initiating a high-strength reduction campaign on the day of the event. The sensitive source zone of Beijing (BJ-Sens) accounts for 54.2% of the total source area of Beijing (BJ), but its reduction effect reaches 89%-100% of the total area, with a reduction efficiency 1.6-1.9 times greater than that of the entire area. The sensitive source zone of Huabei (HuaB-Sens.) only represents 17.6% of the total area of Huabei (HuaB), but its emission reduction effect reaches 59%-97% of the entire area, with a reduction efficiency 4.2-5.5 times greater than that of the total area. The earlier that emission reduction measures are implemented, the greater the effect they have on preventing the transmission of pollutants. In addition, expanding the controlling areas to sensitive provinces and cities around Beijing (HuaB-sens) can significantly accelerate the reduction effects compared to controlling measures only in the Beijing sensitive source zone (BJ-Sens). Therefore, when enacting emission reduction schemes, cooperating with surrounding provinces and cities, as well as narrowing the reduction scope to specific sensitive source zones prior to unfavorable meteorological conditions, can help reduce emissions control costs and improve the efficiency and maneuverability of emission reduction schemes.

  14. Narrow-linewidth, quasi-continuous-wave ASE source based on a multiple-pass Nd:YAG zigzag slab amplifier configuration.

    PubMed

    Chen, Xiaoming; Lu, Yanhua; Hu, Hao; Tong, Lixin; Zhang, Lei; Yu, Yi; Wang, Juntao; Ren, Huaijin; Xu, Liu

    2018-03-05

    We present investigations into a narrow-linewidth, quasi-continuous-wave pulsed all-solid-state amplified spontaneous emission (ASE) source by use of a novel multiple-pass zigzag slab amplifier. The SE fluorescence emitted from a Nd:YAG slab active medium acts as the seed and is amplified back and forth 8 times through the same slab. Thanks to the angular multiplexing nature of the zigzag slab, high-intensity 1064-nm ASE output can be produced without unwanted self-lasing in this configuration. Experimentally, the output energy, optical conversion efficiency, pulse dynamics, spectral property, and beam quality of the ASE source are studied when the Nd:YAG slab end-pumped by two high-brightness laser diode arrays. The maximum single pulse energy of 347 mJ is generated with an optical efficiency of ~5.9% and a beam quality of 3.5/17 in the thickness/width direction of the slab. As expected, smooth pulses without relaxing spikes and continuous spectra are achieved. Moreover, the spectral width of the ASE source narrows versus the pump energy, getting a 3-dB linewidth of as narrow as 20 pm (i.e. 5.3 GHz). Via the sum frequency generation, high-intensity, smooth-pulse, and narrow-linewidth ASE sources are preferred for solving the major problem of saturation of the mesospheric sodium atoms and can create a much brighter sodium guide star to meet the needs of adaptive imaging applications in astronomy.

  15. Massive stereo-based DTM production for Mars on cloud computers

    NASA Astrophysics Data System (ADS)

    Tao, Y.; Muller, J.-P.; Sidiropoulos, P.; Xiong, Si-Ting; Putri, A. R. D.; Walter, S. H. G.; Veitch-Michaelis, J.; Yershov, V.

    2018-05-01

    Digital Terrain Model (DTM) creation is essential to improving our understanding of the formation processes of the Martian surface. Although there have been previous demonstrations of open-source or commercial planetary 3D reconstruction software, planetary scientists are still struggling with creating good quality DTMs that meet their science needs, especially when there is a requirement to produce a large number of high quality DTMs using "free" software. In this paper, we describe a new open source system to overcome many of these obstacles by demonstrating results in the context of issues found from experience with several planetary DTM pipelines. We introduce a new fully automated multi-resolution DTM processing chain for NASA Mars Reconnaissance Orbiter (MRO) Context Camera (CTX) and High Resolution Imaging Science Experiment (HiRISE) stereo processing, called the Co-registration Ames Stereo Pipeline (ASP) Gotcha Optimised (CASP-GO), based on the open source NASA ASP. CASP-GO employs tie-point based multi-resolution image co-registration, and Gotcha sub-pixel refinement and densification. CASP-GO pipeline is used to produce planet-wide CTX and HiRISE DTMs that guarantee global geo-referencing compliance with respect to High Resolution Stereo Colour imaging (HRSC), and thence to the Mars Orbiter Laser Altimeter (MOLA); providing refined stereo matching completeness and accuracy. All software and good quality products introduced in this paper are being made open-source to the planetary science community through collaboration with NASA Ames, United States Geological Survey (USGS) and the Jet Propulsion Laboratory (JPL), Advanced Multi-Mission Operations System (AMMOS) Planetary Data System (PDS) Pipeline Service (APPS-PDS4), as well as browseable and visualisable through the iMars web based Geographic Information System (webGIS) system.

  16. Fully utilizing high power diode lasers by synergizing diode laser light sources and beam shaping micro-optics

    NASA Astrophysics Data System (ADS)

    Fan, Yingmin; Wang, Jingwei; Cai, Lei; Mitra, Thomas; Hauschild, Dirk; Zah, Chung-En; Liu, Xingsheng

    2018-02-01

    High power diode lasers (HPDLs) offer the highest wall-plug efficiency, highest specific power (power-to-weight ratio), arguably the lowest cost and highest reliability among all laser types. However, the poor beam quality of commercially HPDLs is the main bottleneck limiting their direct applications requiring high brightness at least in one dimension. In order to expand the applications of HPDLs, beam shaping and optical design are essential. In this work, we report the recent progresses on maximizing applications of HPDLs by synergizing diode laser light source and beam shaping micro-optics. Successful examples of matching of diode laser light sources and beam shaping micro-optics driving new applications are presented.

  17. Health impairments arising from drinking water polluted with domestic sewage and excreta in China.

    PubMed

    Ling, B

    2000-01-01

    Raw water of poor quality still causes many drinking-water associated health problems all over China, largely because of poor sanitation, inadequate disposal of sewage and excreta. Eutrophication due to excess of total nitrogen and phosphorous in some sources for drinking-water has led to massive proliferation of cyanobacteria. The dominant species of cyanophyta can produce microcystins, a potent liver cancer promotor. As in previous studies, high incidence of liver cancer coincided with high microcystin concentration in the source water, especially in pond water. A frequent consequence of heavy pollution of source water is further the high incidence of infectious intestinal diseases, which are more than 10-100 times as frequent in China than in developed countries.

  18. Pollution loads in urban runoff and sanitary wastewater.

    PubMed

    Taebi, Amir; Droste, Ronald L

    2004-07-05

    While more attention has been paid in recent years to urban point source pollution control through the establishment of wastewater treatment plants in many developing countries, no considerable planning nor any serious measures have been taken to control urban non-point source pollution (urban stormwater runoff). The present study is a screening analysis to investigate the pollution loads in urban runoff compared to point source loads as a first prerequisite for planning and management of receiving water quality. To compare pollutant loads from point and non-point urban sources, the pollutant load is expressed as the weight of pollutant per hectare area per year (kg/ha.year). Unit loads were estimated in stormwater runoff, raw sanitary wastewater and secondary treatment effluents in Isfahan, Iran. Results indicate that the annual pollution load in urban runoff is lower than the annual pollution load in sanitary wastewater in areas with low precipitation but it is higher in areas with high precipitation. Two options, namely, advanced treatment (in lieu of secondary treatment) of sanitary wastewater and urban runoff quality control systems (such as detention ponds) were investigated as controlling systems for pollution discharges into receiving waters. The results revealed that for Isfahan, as a low precipitation urban area, advanced treatment is a more suitable option, but for high precipitation urban areas, urban surface runoff quality control installations were more effective for suspended solids and oxygen-demanding matter controls, and that advanced treatment is the more effective option for nutrient control.

  19. Real-Time Verification of a High-Dose-Rate Iridium 192 Source Position Using a Modified C-Arm Fluoroscope

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nose, Takayuki, E-mail: nose-takayuki@nms.ac.jp; Chatani, Masashi; Otani, Yuki

    Purpose: High-dose-rate (HDR) brachytherapy misdeliveries can occur at any institution, and they can cause disastrous results. Even a patient's death has been reported. Misdeliveries could be avoided with real-time verification methods. In 1996, we developed a modified C-arm fluoroscopic verification of an HDR Iridium 192 source position prevent these misdeliveries. This method provided excellent image quality sufficient to detect errors, and it has been in clinical use at our institutions for 20 years. The purpose of the current study is to introduce the mechanisms and validity of our straightforward C-arm fluoroscopic verification method. Methods and Materials: Conventional X-ray fluoroscopic images aremore » degraded by spurious signals and quantum noise from Iridium 192 photons, which make source verification impractical. To improve image quality, we quadrupled the C-arm fluoroscopic X-ray dose per pulse. The pulse rate was reduced by a factor of 4 to keep the average exposure compliant with Japanese medical regulations. The images were then displayed with quarter-frame rates. Results: Sufficient quality was obtained to enable observation of the source position relative to both the applicators and the anatomy. With this method, 2 errors were detected among 2031 treatment sessions for 370 patients within a 6-year period. Conclusions: With the use of a modified C-arm fluoroscopic verification method, treatment errors that were otherwise overlooked were detected in real time. This method should be given consideration for widespread use.« less

  20. Real-Time Verification of a High-Dose-Rate Iridium 192 Source Position Using a Modified C-Arm Fluoroscope.

    PubMed

    Nose, Takayuki; Chatani, Masashi; Otani, Yuki; Teshima, Teruki; Kumita, Shinichirou

    2017-03-15

    High-dose-rate (HDR) brachytherapy misdeliveries can occur at any institution, and they can cause disastrous results. Even a patient's death has been reported. Misdeliveries could be avoided with real-time verification methods. In 1996, we developed a modified C-arm fluoroscopic verification of an HDR Iridium 192 source position prevent these misdeliveries. This method provided excellent image quality sufficient to detect errors, and it has been in clinical use at our institutions for 20 years. The purpose of the current study is to introduce the mechanisms and validity of our straightforward C-arm fluoroscopic verification method. Conventional X-ray fluoroscopic images are degraded by spurious signals and quantum noise from Iridium 192 photons, which make source verification impractical. To improve image quality, we quadrupled the C-arm fluoroscopic X-ray dose per pulse. The pulse rate was reduced by a factor of 4 to keep the average exposure compliant with Japanese medical regulations. The images were then displayed with quarter-frame rates. Sufficient quality was obtained to enable observation of the source position relative to both the applicators and the anatomy. With this method, 2 errors were detected among 2031 treatment sessions for 370 patients within a 6-year period. With the use of a modified C-arm fluoroscopic verification method, treatment errors that were otherwise overlooked were detected in real time. This method should be given consideration for widespread use. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Recovery Act: Cedarville School District Retrofit of Heating and Cooling Systems with Geothermal Heat Pumps and Ground Source Water Loops

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jarrell, Mark

    Cedarville School District retrofitted the heating and cooling systems in three campus areas (High School, Middle School, and Upper Elementary School) with geothermal heat pumps and ground source water loops, as a demonstration project for the effective implementation of geothermal heat pump systems and other energy efficiency and air quality improvements.

  2. Exotic X-ray Sources from Intermediate Energy Electron Beams

    NASA Astrophysics Data System (ADS)

    Chouffani, K.; Wells, D.; Harmon, F.; Jones, J. L.; Lancaster, G.

    2003-08-01

    High intensity x-ray beams are used in a wide variety of applications in solid-state physics, medicine, biology and material sciences. Synchrotron radiation (SR) is currently the primary, high-quality x-ray source that satisfies both brilliance and tunability. The high cost, large size and low x-ray energies of SR facilities, however, are serious limitations. Alternatively, "novel" x-ray sources are now possible due to new small linear accelerator (LINAC) technology, such as improved beam emittance, low background, sub-Picosecond beam pulses, high beam stability and higher repetition rate. These sources all stem from processes that produce Radiation from relativistic Electron beams in (crystalline) Periodic Structures (REPS), or the periodic "structure" of laser light. REPS x-ray sources are serious candidates for bright, compact, portable, monochromatic, and tunable x-ray sources with varying degrees of polarization and coherence. Despite the discovery and early research into these sources over the past 25 years, these sources are still in their infancy. Experimental and theoretical research are still urgently needed to answer fundamental questions about the practical and ultimate limits of their brightness, mono-chromaticity etc. We present experimental results and theoretical comparisons for three exotic REPS sources. These are Laser-Compton Scattering (LCS), Channeling Radiation (CR) and Parametric X-Radiation (PXR).

  3. Latino and Non-Latino Perceptions of the Air Quality in California's San Joaquin Valley.

    PubMed

    Brown, Paul; Cameron, Linda; Cisneros, Ricardo; Cox, Rachel; Gaab, Erin; Gonzalez, Mariaelena; Ramondt, Steven; Song, Anna

    2016-12-15

    The San Joaquin Valley (SJV) of California has poor air quality, high rates of asthma, and high rates of obesity. Informational campaigns aimed at increasing awareness of the health impacts of poor air quality and promoting behavior change need to be tailored to the specific target audiences. The study examined perceptions of air quality, perceived health impacts, and methods of accessing information about air quality between Latinos and other groups in the SJV. Residents of the SJV (n = 744) where surveyed via one of three methods: community organizations (256), public locations (251), and an internet panel (237). The results suggest that people perceive the air quality in their region to be generally unhealthy, particularly for sensitive groups. The air quality is more likely to be reported as being unhealthy by people with health problems and less unhealthy by Latinos and people who report regularly exercising. Latinos are more likely to report working outdoors regularly, but also more likely to report being able to reduce their exposure if the air quality is unhealthy. The results report differences in informational sources about air quality, suggesting that informational campaigns should target high risk groups using a variety of media.

  4. Latino and Non-Latino Perceptions of the Air Quality in California’s San Joaquin Valley

    PubMed Central

    Brown, Paul; Cameron, Linda; Cisneros, Ricardo; Cox, Rachel; Gaab, Erin; Gonzalez, Mariaelena; Ramondt, Steven; Song, Anna

    2016-01-01

    The San Joaquin Valley (SJV) of California has poor air quality, high rates of asthma, and high rates of obesity. Informational campaigns aimed at increasing awareness of the health impacts of poor air quality and promoting behavior change need to be tailored to the specific target audiences. The study examined perceptions of air quality, perceived health impacts, and methods of accessing information about air quality between Latinos and other groups in the SJV. Residents of the SJV (n = 744) where surveyed via one of three methods: community organizations (256), public locations (251), and an internet panel (237). The results suggest that people perceive the air quality in their region to be generally unhealthy, particularly for sensitive groups. The air quality is more likely to be reported as being unhealthy by people with health problems and less unhealthy by Latinos and people who report regularly exercising. Latinos are more likely to report working outdoors regularly, but also more likely to report being able to reduce their exposure if the air quality is unhealthy. The results report differences in informational sources about air quality, suggesting that informational campaigns should target high risk groups using a variety of media. PMID:27983706

  5. Data governance in predictive toxicology: A review.

    PubMed

    Fu, Xin; Wojak, Anna; Neagu, Daniel; Ridley, Mick; Travis, Kim

    2011-07-13

    Due to recent advances in data storage and sharing for further data processing in predictive toxicology, there is an increasing need for flexible data representations, secure and consistent data curation and automated data quality checking. Toxicity prediction involves multidisciplinary data. There are hundreds of collections of chemical, biological and toxicological data that are widely dispersed, mostly in the open literature, professional research bodies and commercial companies. In order to better manage and make full use of such large amount of toxicity data, there is a trend to develop functionalities aiming towards data governance in predictive toxicology to formalise a set of processes to guarantee high data quality and better data management. In this paper, data quality mainly refers in a data storage sense (e.g. accuracy, completeness and integrity) and not in a toxicological sense (e.g. the quality of experimental results). This paper reviews seven widely used predictive toxicology data sources and applications, with a particular focus on their data governance aspects, including: data accuracy, data completeness, data integrity, metadata and its management, data availability and data authorisation. This review reveals the current problems (e.g. lack of systematic and standard measures of data quality) and desirable needs (e.g. better management and further use of captured metadata and the development of flexible multi-level user access authorisation schemas) of predictive toxicology data sources development. The analytical results will help to address a significant gap in toxicology data quality assessment and lead to the development of novel frameworks for predictive toxicology data and model governance. While the discussed public data sources are well developed, there nevertheless remain some gaps in the development of a data governance framework to support predictive toxicology. In this paper, data governance is identified as the new challenge in predictive toxicology, and a good use of it may provide a promising framework for developing high quality and easy accessible toxicity data repositories. This paper also identifies important research directions that require further investigation in this area.

  6. Data governance in predictive toxicology: A review

    PubMed Central

    2011-01-01

    Background Due to recent advances in data storage and sharing for further data processing in predictive toxicology, there is an increasing need for flexible data representations, secure and consistent data curation and automated data quality checking. Toxicity prediction involves multidisciplinary data. There are hundreds of collections of chemical, biological and toxicological data that are widely dispersed, mostly in the open literature, professional research bodies and commercial companies. In order to better manage and make full use of such large amount of toxicity data, there is a trend to develop functionalities aiming towards data governance in predictive toxicology to formalise a set of processes to guarantee high data quality and better data management. In this paper, data quality mainly refers in a data storage sense (e.g. accuracy, completeness and integrity) and not in a toxicological sense (e.g. the quality of experimental results). Results This paper reviews seven widely used predictive toxicology data sources and applications, with a particular focus on their data governance aspects, including: data accuracy, data completeness, data integrity, metadata and its management, data availability and data authorisation. This review reveals the current problems (e.g. lack of systematic and standard measures of data quality) and desirable needs (e.g. better management and further use of captured metadata and the development of flexible multi-level user access authorisation schemas) of predictive toxicology data sources development. The analytical results will help to address a significant gap in toxicology data quality assessment and lead to the development of novel frameworks for predictive toxicology data and model governance. Conclusions While the discussed public data sources are well developed, there nevertheless remain some gaps in the development of a data governance framework to support predictive toxicology. In this paper, data governance is identified as the new challenge in predictive toxicology, and a good use of it may provide a promising framework for developing high quality and easy accessible toxicity data repositories. This paper also identifies important research directions that require further investigation in this area. PMID:21752279

  7. Mechanical design and fabrication of the VHF-gun, the Berkeley normal-conducting continuous-wave high-brightness electron source

    NASA Astrophysics Data System (ADS)

    Wells, R. P.; Ghiorso, W.; Staples, J.; Huang, T. M.; Sannibale, F.; Kramasz, T. D.

    2016-02-01

    A high repetition rate, MHz-class, high-brightness electron source is a key element in future high-repetition-rate x-ray free electron laser-based light sources. The VHF-gun, a novel low frequency radio-frequency gun, is the Lawrence Berkeley National Laboratory (LBNL) response to that need. The gun design is based on a normal conducting, single cell cavity resonating at 186 MHz in the VHF band and capable of continuous wave operation while still delivering the high accelerating fields at the cathode required for the high brightness performance. The VHF-gun was fabricated and successfully commissioned in the framework of the Advanced Photo-injector EXperiment, an injector built at LBNL to demonstrate the capability of the gun to deliver the required beam quality. The basis for the selection of the VHF-gun technology, novel design features, and fabrication techniques are described.

  8. Mechanical design and fabrication of the VHF-gun, the Berkeley normal-conducting continuous-wave high-brightness electron source.

    PubMed

    Wells, R P; Ghiorso, W; Staples, J; Huang, T M; Sannibale, F; Kramasz, T D

    2016-02-01

    A high repetition rate, MHz-class, high-brightness electron source is a key element in future high-repetition-rate x-ray free electron laser-based light sources. The VHF-gun, a novel low frequency radio-frequency gun, is the Lawrence Berkeley National Laboratory (LBNL) response to that need. The gun design is based on a normal conducting, single cell cavity resonating at 186 MHz in the VHF band and capable of continuous wave operation while still delivering the high accelerating fields at the cathode required for the high brightness performance. The VHF-gun was fabricated and successfully commissioned in the framework of the Advanced Photo-injector EXperiment, an injector built at LBNL to demonstrate the capability of the gun to deliver the required beam quality. The basis for the selection of the VHF-gun technology, novel design features, and fabrication techniques are described.

  9. Trends of multiple air pollutants emissions from residential coal combustion in Beijing and its implication on improving air quality for control measures

    NASA Astrophysics Data System (ADS)

    Xue, Yifeng; Zhou, Zhen; Nie, Teng; Wang, Kun; Nie, Lei; Pan, Tao; Wu, Xiaoqing; Tian, Hezhong; Zhong, Lianhong; Li, Jing; Liu, Huanjia; Liu, Shuhan; Shao, Panyang

    2016-10-01

    Residential coal combustion is considered to be an important source of air pollution in Beijing. However, knowledge regarding the emission characteristics of residential coal combustion and the related impacts on the air quality is very limited. In this study, we have developed an emission inventory for multiple hazardous air pollutants (HAPs) associated with residential coal combustion in Beijing for the period of 2000-2012. Furthermore, a widely used regional air quality model, the Community Multi-Scale Air Quality model (CMAQ), is applied to analyze the impact of residential coal combustion on the air quality in Beijing in 2012. The results show that the emissions of primary air pollutants from residential coal combustion have basically remained the same levels during the past decade, however, along with the strict emission control imposed on major industrial sources, the contribution of residential coal combustion emissions to the overall emissions from anthropogenic sources have increased obviously. In particular, the contributions of residential coal combustion to the total air pollutants concentrations of PM10, SO2, NOX, and CO represent approximately 11.6%, 27.5%, 2.8% and 7.3%, respectively, during the winter heating season. In terms of impact on the spatial variation patterns, the distributions of the pollutants concentrations are similar to the distribution of the associated primary HAPs emissions, which are highly concentrated in the rural-urban fringe zones and rural suburb areas. In addition, emissions of primary pollutants from residential coal combustion are forecasted by using a scenario analysis. Generally, comprehensive measures must be taken to control residential coal combustion in Beijing. The best way to reduce the associated emissions from residential coal combustion is to use economic incentive means to promote the conversion to clean energy sources for residential heating and cooking. In areas with reliable energy supplies, the coal used for residential heating can be replaced with gas-burning wall-heaters, ground-source heat pumps, solar energy and electricity. In areas with inadequate clean energy sources, low-sulfur coal should be used instead of the traditional raw coal with high sulfur and ash content, thereby slightly reducing the emissions of PM, SO2, CO and other toxic pollutants.

  10. Interventions to improve water quality for preventing diarrhoea

    PubMed Central

    Clasen, Thomas F; Alexander, Kelly T; Sinclair, David; Boisson, Sophie; Peletz, Rachel; Chang, Howard H; Majorin, Fiona; Cairncross, Sandy

    2015-01-01

    Background Diarrhoea is a major cause of death and disease, especially among young children in low-income countries. In these settings, many infectious agents associated with diarrhoea are spread through water contaminated with faeces. In remote and low-income settings, source-based water quality improvement includes providing protected groundwater (springs, wells, and bore holes), or harvested rainwater as an alternative to surface sources (rivers and lakes). Point-of-use water quality improvement interventions include boiling, chlorination, flocculation, filtration, or solar disinfection, mainly conducted at home. Objectives To assess the effectiveness of interventions to improve water quality for preventing diarrhoea. Search methods We searched the Cochrane Infectious Diseases Group Specialized Register (11 November 2014), CENTRAL (the Cochrane Library, 7 November 2014), MEDLINE (1966 to 10 November 2014), EMBASE (1974 to 10 November 2014), and LILACS (1982 to 7 November 2014). We also handsearched relevant conference proceedings, contacted researchers and organizations working in the field, and checked references from identified studies through 11 November 2014. Selection criteria Randomized controlled trials (RCTs), quasi-RCTs, and controlled before-and-after studies (CBA) comparing interventions aimed at improving the microbiological quality of drinking water with no intervention in children and adults. Data collection and analysis Two review authors independently assessed trial quality and extracted data. We used meta-analyses to estimate pooled measures of effect, where appropriate, and investigated potential sources of heterogeneity using subgroup analyses. We assessed the quality of evidence using the GRADE approach. Main results Forty-five cluster-RCTs, two quasi-RCTs, and eight CBA studies, including over 84,000 participants, met the inclusion criteria. Most included studies were conducted in low- or middle-income countries (LMICs) (50 studies) with unimproved water sources (30 studies) and unimproved or unclear sanitation (34 studies). The primary outcome in most studies was self-reported diarrhoea, which is at high risk of bias due to the lack of blinding in over 80% of the included studies. Source-based water quality improvements There is currently insufficient evidence to know if source-based improvements such as protected wells, communal tap stands, or chlorination/filtration of community sources consistently reduce diarrhoea (one cluster-RCT, five CBA studies, very low quality evidence). We found no studies evaluating reliable piped-in water supplies delivered to households. Point-of-use water quality interventions On average, distributing water disinfection products for use at the household level may reduce diarrhoea by around one quarter (Home chlorination products: RR 0.77, 95% CI 0.65 to 0.91; 14 trials, 30,746 participants, low quality evidence; flocculation and disinfection sachets: RR 0.69, 95% CI 0.58 to 0.82, four trials, 11,788 participants, moderate quality evidence). However, there was substantial heterogeneity in the size of the effect estimates between individual studies. Point-of-use filtration systems probably reduce diarrhoea by around a half (RR 0.48, 95% CI 0.38 to 0.59, 18 trials, 15,582 participants, moderate quality evidence). Important reductions in diarrhoea episodes were shown with ceramic filters, biosand systems and LifeStraw® filters; (Ceramic: RR 0.39, 95% CI 0.28 to 0.53; eight trials, 5763 participants, moderate quality evidence; Biosand: RR 0.47, 95% CI 0.39 to 0.57; four trials, 5504 participants, moderate quality evidence; LifeStraw®: RR 0.69, 95% CI 0.51 to 0.93; three trials, 3259 participants, low quality evidence). Plumbed in filters have only been evaluated in high-income settings (RR 0.81, 95% CI 0.71 to 0.94, three trials, 1056 participants, fixed effects model). In low-income settings, solar water disinfection (SODIS) by distribution of plastic bottles with instructions to leave filled bottles in direct sunlight for at least six hours before drinking probably reduces diarrhoea by around a third (RR 0.62, 95% CI 0.42 to 0.94; four trials, 3460 participants, moderate quality evidence). In subgroup analyses, larger effects were seen in trials with higher adherence, and trials that provided a safe storage container. In most cases, the reduction in diarrhoea shown in the studies was evident in settings with improved and unimproved water sources and sanitation. Authors' conclusions Interventions that address the microbial contamination of water at the point-of-use may be important interim measures to improve drinking water quality until homes can be reached with safe, reliable, piped-in water connections. The average estimates of effect for each individual point-of-use intervention generally show important effects. Comparisons between these estimates do not provide evidence of superiority of one intervention over another, as such comparisons are confounded by the study setting, design, and population. Further studies assessing the effects of household connections and chlorination at the point of delivery will help improve our knowledge base. As evidence suggests effectiveness improves with adherence, studies assessing programmatic approaches to optimising coverage and long-term utilization of these interventions among vulnerable populations could also help strategies to improve health outcomes. PLAIN LANGUAGE SUMMARY Interventions to improve water quality and prevent diarrhoea This Cochrane Review summarizes trials evaluating different interventions to improve water quality and prevent diarrhoea. After searching for relevant trials up to 11 November 2014, we included 55 studies enrolling over 84,000 participants. Most included studies were conducted in low- or middle-income countries (LMICs) (50 studies), with unimproved water sources (30 studies), and unimproved or unclear sanitation (34 studies). What causes diarrhoea and what water quality interventions might prevent diarrhoea? Diarrhoea is a major cause of death and disease, especially among young children in low-income countries where the most common causes are faecally contaminated water and food, or poor hygiene practices. In remote and low-income settings, source-based water quality improvement may include providing protected groundwater (springs, wells, and bore holes) or harvested rainwater as an alternative to surface sources (rivers and lakes). Alternatively water may be treated at the point-of-use in people's homes by boiling, chlorination, flocculation, filtration, or solar disinfection. These point-of-use interventions have the potential to overcome both contaminated sources and recontamination of safe water in the home. What the research says There is currently insufficient evidence to know if source-based improvements in water supplies, such as protected wells and communal tap stands or treatment of communal supplies, consistently reduce diarrhoea in low-income settings (very low quality evidence). We found no trials evaluating reliable piped-in water supplies to people's homes. On average, distributing disinfection products for use in the home may reduce diarrhoea by around one quarter in the case of chlorine products (low quality evidence), and around a third in the case of flocculation and disinfection sachets (moderate quality evidence). Water filtration at home probably reduces diarrhoea by around a half (moderate quality evidence), and effects were consistently seen with ceramic filters (moderate quality evidence), biosand systems (moderate quality evidence) and LifeStraw® filters (low quality evidence). Plumbed-in filtration has only been evaluated in high-income settings (low quality evidence). In low-income settings, distributing plastic bottles with instructions to leave filled bottles in direct sunlight for at least six hours before drinking probably reduces diarrhoea by around a third (moderate quality evidence). Research assessing the effects of household connections and chlorination at the point of delivery will help improve our knowledge base. Evidence indicates the more people use the various interventions for improving water quality, the larger the effects, so research into practical approaches to increase coverage and help assure long term use of them in poor groups will help improve impact. PMID:26488938

  11. Initial Experience of the Application of Automated Tube Potential Selection Technique in High-pitch Dual-source CT Angiography of Whole Aorta Using Third-generation Dual-source CT Scanner.

    PubMed

    Kong, Lingyan; Liang, Jixiang; Xue, Huadan; Wang, Yining; Wang, Yun; Jin, Zhengyu; Zhang, Daming; Chen, Jin

    2017-02-20

    Objective To evaluate the application of automated tube potential selection technique in high-pitch dual-source CT aortic angiography on a third-generation dual-source CT scanner. Methods Whole aorta angiography were indiated in 59 patients,who were divided into 2 groups using a simple random method:in group 1 there were 31 patients who underwent the examination with automated tube potential selection using a vascular setting with a preferred image quality of 288 mA/100 kV;in group 2 there were 28 patients who underwent the examination with a tube voltage of 100 kV and automated tube current modulation using a reference tube current of 288 mA. Both groups were scanned on a third generation dual-source CT device operated in dual-source high-pitch ECG-gating mode with a pitch of 3.0,collimation of 2×192×0.6 mm,and a rotation time of 0.25 s. Iterative reconstruction algorithm was used. For group 1,the volume and flow of contrast medium and chasing saline were adapted to the tube voltage. For group 2,a contrast material bolus of 45 ml with a flow of 4.5 ml/s followed by a 50 ml saline chaser at 5 ml/s was used. CTA scan was automatically started using a bolus tracking technique at the level of the original part of aorta after a trigger threshold of 100 HU was reached. The start delay was set to 6 s in both groups. Effective dose (ED),signal to noise ratio (SNR),contrast to noise ratio (CNR),and subjective diagnostic quality of both groups were evaluated. Results The mean ED were 21.3% lower (t=-3.099,P=0.000) in group 1 [(2.48±0.80) mSv] than in group 2 [(3.15±0.86) mSv]. Two groups showed no significant difference in attenuation,SD,SNR,or CNR at all evaluational parts of aorta (ascending aorta,aortic arch,diaphragmatic aorta,or iliac bifurcation)(all P>0.05). There was no significant difference in subjective diagnostic quality values of two groups [(1.41±0.50) scores vs. (1.39±0.50) scores;W=828.5,P=0.837]. Conclusion Compared with automated tube current modulation,the automated tube potential selection technique in aorta CT angiography on a third-generation dual-source CT can dramatically reduce radiation dose without affecting image quality.

  12. Effects of flow diversions on water and habitat quality: Examples from California's highly manipulated Sacramento–San Joaquin Delta

    USGS Publications Warehouse

    Monsen, Nancy E.; Cloern, James E.; Burau, Jon R.

    2007-01-01

    We use selected monitoring data to illustrate how localized water diversions from seasonal barriers, gate operations, and export pumps alter water quality across the Sacramento-San Joaquin Delta (California). Dynamics of water-quality variability are complex because the Delta is a mixing zone of water from the Sacramento and San Joaquin Rivers, agricultural return water, and the San Francisco Estuary. Each source has distinct water-quality characteristics, and the contribution of each source varies in response to natural hydrologic variability and water diversions. We use simulations with a tidal hydrodynamic model to reveal how three diversion events, as case studies, influence water quality through their alteration of Delta-wide water circulation patterns and flushing time. Reduction of export pumping decreases the proportion of Sacramento- to San Joaquin-derived fresh water in the central Delta, leading to rapid increases in salinity. Delta Cross Channel gate operations control salinity in the western Delta and alter the freshwater source distribution in the central Delta. Removal of the head of Old River barrier, in autumn, increases the flushing time of the Stockton Ship Channel from days to weeks, contributing to a depletion of dissolved oxygen. Each shift in water quality has implications either for habitat quality or municipal drinking water, illustrating the importance of a systems view to anticipate the suite of changes induced by flow manipulations, and to minimize the conflicts inherent in allocations of scarce resources to meet multiple objectives.

  13. Long-term trends of ambient particulate matter emission source contributions and the accountability of control strategies in Hong Kong over 1998-2008

    NASA Astrophysics Data System (ADS)

    Yuan, Zibing; Yadav, Varun; Turner, Jay R.; Louie, Peter K. K.; Lau, Alexis Kai Hon

    2013-09-01

    Despite extensive emission control measures targeting motor vehicles and to a lesser extent other sources, annual-average PM10 mass concentrations in Hong Kong have remained relatively constant for the past several years and for some air quality metrics, such as the frequency of poor visibility days, conditions have degraded. The underlying drivers for these long-term trends were examined by performing source apportionment on eleven years (1998-2008) of data for seven monitoring sites in the Hong Kong PM10 chemical speciation network. Nine factors were resolved using Positive Matrix Factorization. These factors were assigned to emission source categories that were classified as local (operationally defined as within the Hong Kong Special Administrative Region) or non-local based on temporal and spatial patterns in the source contribution estimates. This data-driven analysis provides strong evidence that local controls on motor vehicle emissions have been effective in reducing motor vehicle-related ambient PM10 burdens with annual-average contributions at neighborhood- and larger-scale monitoring stations decreasing by ˜6 μg m-3 over the eleven year period. However, this improvement has been offset by an increase in annual-average contributions from non-local contributions, especially secondary sulfate and nitrate, of ˜8 μg m-3 over the same time period. As a result, non-local source contributions to urban-scale PM10 have increased from 58% in 1998 to 70% in 2008. Most of the motor vehicle-related decrease and non-local source driven increase occurred over the period 1998-2004 with more modest changes thereafter. Non-local contributions increased most dramatically for secondary sulfate and secondary nitrate factors and thus combustion-related control strategies, including but not limited to power plants, are needed for sources located in the Pearl River Delta and more distant regions to improve air quality conditions in Hong Kong. PMF-resolved source contribution estimates were also used to examine differential contributions of emission source categories during high PM episodes compared to study-average behavior. While contributions from all source categories increased to some extent on high PM days, the increases were disproportionately high for the non-local sources. Thus, controls on emission sources located outside the Hong Kong Special Administrative Region will be needed to effectively decrease the frequency and severity of high PM episodes.

  14. What Air Quality Models Tell Us About Sources and Sinks of Atmospheric Aldehydes

    NASA Astrophysics Data System (ADS)

    Luecken, D.; Hutzell, W. T.; Phillips, S.

    2010-12-01

    Atmospheric aldehydes play important roles in several aspects of air quality: they are critical radical sources that drive ozone formation, they are hazardous air pollutants that are national drivers for cancer risk, they participate in aqueous chemistry and potentially aerosol formation, and are key species for evaluating the accuracy of isoprene emissions. For these reasons, it is important to accurately understand their sources and sinks, and the sensitivity of their concentrations to emission controls. While both compounds have been included in air quality modeling for many years, current, state-of-the-science chemical mechanisms have difficulty reproducing measured values of aldehydes, which calls into question the robustness of ozone, HAPs and aerosol predictions. In the past, we have attributed discrepancies to measurement errors, inventory errors, or the focus on high-NOx urban regimes. Despite improvements in all of these areas, the measurements still diverge from model predictions, with formaldehyde often underpredicted by 50% and acetaldehyde showing a large degree of scatter - from 20% overprediction to 50% underprediction. To better examine the sources of aldehydes, we implemented the new SAPRC07T mechanism in the Community Multi-Scale Air Quality (CMAQ) model. This mechanism incorporates current recommendations for kinetic data and has the most detailed representation of product formation under a wide variety of conditions of any mechanism used in regional air quality models. We use model simulations to pinpoint where and when aldehyde concentrations tend to deviate from measurements. We demonstrate the role of secondary production versus primary emissions in aldehdye concentrations and find that secondary sources produce the largest deviations from measurements. We identify which VOCs are most responsible for aldehyde secondary production in the areas of the U.S. where the largest health effects are seen, and discuss how this affects consideration of control strategies.

  15. Analysis of feature selection with Probabilistic Neural Network (PNN) to classify sources influencing indoor air quality

    NASA Astrophysics Data System (ADS)

    Saad, S. M.; Shakaff, A. Y. M.; Saad, A. R. M.; Yusof, A. M.; Andrew, A. M.; Zakaria, A.; Adom, A. H.

    2017-03-01

    There are various sources influencing indoor air quality (IAQ) which could emit dangerous gases such as carbon monoxide (CO), carbon dioxide (CO2), ozone (O3) and particulate matter. These gases are usually safe for us to breathe in if they are emitted in safe quantity but if the amount of these gases exceeded the safe level, they might be hazardous to human being especially children and people with asthmatic problem. Therefore, a smart indoor air quality monitoring system (IAQMS) is needed that able to tell the occupants about which sources that trigger the indoor air pollution. In this project, an IAQMS that able to classify sources influencing IAQ has been developed. This IAQMS applies a classification method based on Probabilistic Neural Network (PNN). It is used to classify the sources of indoor air pollution based on five conditions: ambient air, human activity, presence of chemical products, presence of food and beverage, and presence of fragrance. In order to get good and best classification accuracy, an analysis of several feature selection based on data pre-processing method is done to discriminate among the sources. The output from each data pre-processing method has been used as the input for the neural network. The result shows that PNN analysis with the data pre-processing method give good classification accuracy of 99.89% and able to classify the sources influencing IAQ high classification rate.

  16. A sparsity-based iterative algorithm for reconstruction of micro-CT images from highly undersampled projection datasets obtained with a synchrotron X-ray source

    NASA Astrophysics Data System (ADS)

    Melli, S. Ali; Wahid, Khan A.; Babyn, Paul; Cooper, David M. L.; Gopi, Varun P.

    2016-12-01

    Synchrotron X-ray Micro Computed Tomography (Micro-CT) is an imaging technique which is increasingly used for non-invasive in vivo preclinical imaging. However, it often requires a large number of projections from many different angles to reconstruct high-quality images leading to significantly high radiation doses and long scan times. To utilize this imaging technique further for in vivo imaging, we need to design reconstruction algorithms that reduce the radiation dose and scan time without reduction of reconstructed image quality. This research is focused on using a combination of gradient-based Douglas-Rachford splitting and discrete wavelet packet shrinkage image denoising methods to design an algorithm for reconstruction of large-scale reduced-view synchrotron Micro-CT images with acceptable quality metrics. These quality metrics are computed by comparing the reconstructed images with a high-dose reference image reconstructed from 1800 equally spaced projections spanning 180°. Visual and quantitative-based performance assessment of a synthetic head phantom and a femoral cortical bone sample imaged in the biomedical imaging and therapy bending magnet beamline at the Canadian Light Source demonstrates that the proposed algorithm is superior to the existing reconstruction algorithms. Using the proposed reconstruction algorithm to reduce the number of projections in synchrotron Micro-CT is an effective way to reduce the overall radiation dose and scan time which improves in vivo imaging protocols.

  17. Small Drinking Water System Initiative | Drinking Water in New ...

    EPA Pesticide Factsheets

    2017-07-06

    Reliable, safe, high quality drinking water is essential to sustaining our communities. Approximately 90% of New England's drinking water systems - about 10,000 systems - are small and most use ground water sources.

  18. QCL seeded, ns-pulse, multi-line, CO2 laser oscillator for laser-produced-plasma extreme-UV source

    NASA Astrophysics Data System (ADS)

    Nowak, Krzysztof Michał; Suganuma, Takashi; Kurosawa, Yoshiaki; Ohta, Takeshi; Kawasuji, Yasufumi; Nakarai, Hiroaki; Saitou, Takashi; Fujimoto, Junichi; Mizoguchi, Hakaru; Sumitani, Akira; Endo, Akira

    2017-01-01

    Successful merger of state-of-the-art, semiconductor quantum-cascade lasers (QCL), with the mature CO2 laser technology, resulted in a delivery of highly-desired qualities of CO2 laser output that were not available previously without much effort. These qualities, such as multi-line operation, excellent spectro-temporal stability and pulse waveform control, became available from a single device of moderate complexity. This paper describes the operation principle and the unique properties of the solid{state seeded CO2 laser, invented for an application in laser-produced-plasma (LPP), extreme-UV (EUV) light source.

  19. Requirements UML Tool (RUT) Expanded for Extreme Programming (CI02)

    NASA Technical Reports Server (NTRS)

    McCoy, James R.

    2003-01-01

    A procedure for capturing and managing system requirements that incorporates XP user stories. Because costs associated with identifying problems in requirements increase dramatically over the lifecycle of a project, a method for identifying sources of software risks in user stories is urgently needed. This initiative aims to determine a set of guide-lines for user stories that will result in high-quality requirement. To further this initiative, a tool is needed to analyze user stories that can assess the quality of individual user stories, detect sources cf software risk's, produce software metrics, and identify areas in user stories that can be improved.

  20. VizieR Online Data Catalog: Hi-GAL. inner Milky Way: +68>=l>=70 (Molinari+, 2016)

    NASA Astrophysics Data System (ADS)

    Molinari, S.; Schisano, E.; Elia, D.; Pestalozzi, M.; Traficante, A.; Pezzuto, S.; Swinyard, B. M.; Noriega-Crespo, A.; Bally, J.; Moore, T. J. T.; Plume, R.; Zavagno, A.; di Giorgio A. M.; Liu, S. J.; Pilbratt, G. L.; Mottram, J. C.; Russeil, D.; Piazzo, L.; Veneziani, M.; Benedettini, M.; Calzoletti, L.; Faustini, F.; Natoli, P.; Piacentini, F.; Merello, M.; Palmese, A.; Del Grande, R.; Polychroni, D.; Rygl, K. L. J.; Polenta, G.; Barlow, M. J.; Bernard, J.-P.; Martin, P. G.; Testi, L.; Ali, B.; Andre, P.; Beltran, M. T.; Billot, N.; Carey, S.; Cesaroni, R.; Compiegne, M.; Eden, D.; Fukui, Y.; Garcia-Lario, P.; Hoare, M. G.; Huang, M.; Joncas, G.; Lim, T. L.; Lord, S. D.; Martinavarro-Armengol, S.; Motte, F.; Paladini, R.; Paradis, D.; Peretto, N.; Robitaille, T.; Schilke, P.; Schneider, N.; Schulz, B.; Sibthorpe, B.; Strafella, F.; Thompson, M. A.; Umana, G.; Ward-Thompson, D.; Wyrowski, F.

    2016-08-01

    This is the first public data release of high-quality products from the Herschel Hi-GAL survey. The release comes two years after the end of the Herschel observing campaign and is the result of extensive testing of the data reduction and extraction procedures created by members of the Hi-GAL consortium. The complexity and the large variation of the background conditions in all Herschel wavelength bands makes source extraction on the Galactic plane a challenging task. With Hi-GAL DR1, we provide access (http://vialactea.iaps.inaf.it) through a cutout service to high-quality images and compact source catalogues for the Galactic plane at 70, 160, 250, 350, and 500um in the region 68°>=l>=-70° and |b|<= 1°. (6 data files).

  1. Mapping of chlorophyll a distributions in coastal zones

    NASA Technical Reports Server (NTRS)

    Johnson, R. W.

    1978-01-01

    It is pointed out that chlorophyll a is an important environmental parameter for monitoring water quality, nutrient loads, and pollution effects in coastal zones. High chlorophyll a concentrations occur in areas which have high nutrient inflows from sources such as sewage treatment plants and industrial wastes. Low chlorophyll a concentrations may be due to the addition of toxic substances from industrial wastes or other sources. Remote sensing provides an opportunity to assess distributions of water quality parameters, such as chlorophyll a. A description is presented of the chlorophyll a analysis and a quantitative mapping of the James River, Virginia. An approach considered by Johnson (1977) was used in the analysis. An application of the multiple regression analysis technique to a data set collected over the New York Bight, an environmentally different area of the coastal zone, is also discussed.

  2. Combined use of stable isotopes and hydrologic modeling to better understand nutrient sources and cycling in highly altered systems (Invited)

    NASA Astrophysics Data System (ADS)

    Young, M. B.; Kendall, C.; Guerin, M.; Stringfellow, W. T.; Silva, S. R.; Harter, T.; Parker, A.

    2013-12-01

    The Sacramento and San Joaquin Rivers provide the majority of freshwater for the San Francisco Bay Delta. Both rivers are important sources of drinking and irrigation water for California, and play critical roles in the health of California fisheries. Understanding the factors controlling water quality and primary productivity in these rivers and the Delta is essential for making sound economic and environmental water management decisions. However, these highly altered surface water systems present many challenges for water quality monitoring studies due to factors such as multiple potential nutrient and contaminant inputs, dynamic source water inputs, and changing flow regimes controlled by both natural and engineered conditions. The watersheds for both rivers contain areas of intensive agriculture along with many other land uses, and the Sacramento River receives significant amounts of treated wastewater from the large population around the City of Sacramento. We have used a multi-isotope approach combined with mass balance and hydrodynamic modeling in order to better understand the dominant nutrient sources for each of these rivers, and to track nutrient sources and cycling within the complex Delta region around the confluence of the rivers. High nitrate concentrations within the San Joaquin River fuel summer algal blooms, contributing to low dissolved oxygen conditions. High δ15N-NO3 values combined with the high nitrate concentrations suggest that animal manure is a significant source of nitrate to the San Joaquin River. In contrast, the Sacramento River has lower nitrate concentrations but elevated ammonium concentrations from wastewater discharge. Downstream nitrification of the ammonium can be clearly traced using δ15N-NH4. Flow conditions for these rivers and the Delta have strong seasonal and inter-annual variations, resulting in significant changes in nutrient delivery and cycling. Isotopic measurements and estimates of source water contributions derived from the DSM2-HYDRO hydrologic model demonstrate that mixing between San Joaquin and Sacramento River water can occur as far as 30 miles upstream of the confluence within the San Joaquin channel, and that San Joaquin-derived nitrate only reaches the western Delta during periods of high flow.

  3. Temporal changes in the vertical distribution of flow and chloride in deep wells

    USGS Publications Warehouse

    Izbicki, John A.; Christensen, Allen H.; Newhouse, Mark W.; Smith, Gregory A.; Hanson, Randall T.

    2005-01-01

    The combination of flowmeter and depth-dependent water-quality data was used to evaluate the quantity and source of high-chloride water yielded from different depths to eight production wells in the Pleasant Valley area of southern California. The wells were screened from 117 to 437 m below land surface, and in most cases, flow from the aquifer into the wells was not uniformly distributed throughout the well screen. Wells having as little as 6 m of screen in the overlying upper aquifer system yielded as much as 50% of their water from the upper system during drought periods, while the deeper parts of the well screens yielded 15% or less of the total yield of the wells. Mixing of water within wells during pumping degraded higher-quality water with poorer-quality water from deeper depths, and in some cases with poorer-quality water from the overlying upper aquifer system. Changes in the mixture of water within a well, resulting from changes in the distribution of flow into the well, changed the quality of water from the surface discharge of wells over time. The combination of flowmeter and depth-dependent water quality data yielded information about sources of high-chloride water to wells that was not available on the basis of samples collected from nearby observation wells. Changing well design to eliminate small quantities of poor-quality water from deeper parts of the well may improve the quality of water from some wells without greatly reducing well yield. Copyright ?? 2005 National Ground Water Association.

  4. The quality and readability of online consumer information about gynecologic cancer.

    PubMed

    Sobota, Aleksandra; Ozakinci, Gozde

    2015-03-01

    The Internet has become an important source of health-related information for consumers, among whom younger women constitute a notable group. The aims of this study were (1) to evaluate the quality and readability of online information about gynecologic cancer using validated instruments and (2) to relate the quality of information to its readability. Using the Alexa Rank, we obtained a list of 35 Web pages providing information about 7 gynecologic malignancies. These were assessed using the Health on the Net (HON) seal of approval, the Journal of the American Medical Association (JAMA) benchmarks, and the DISCERN instrument. Flesch readability score was calculated for sections related to symptoms and signs and treatment. Less than 30% of the Web pages displayed the HON seal or achieved all JAMA benchmarks. The majority of the treatment sections were of moderate to high quality according to the DISCERN. There was no significant relationship between the presence of the HON seal and readability. Web pages achieving all JAMA benchmarks were significantly more difficult to read and understand than Web pages that missed any of the JAMA benchmarks. Treatment-related content of moderate to high quality as assessed by the DISCERN had a significantly better readability score than the low-quality content. The online information about gynecologic cancer provided by the most frequently visited Web pages is of variable quality and in general difficult to read and understand. The relationship between the quality and readability remains unclear. Health care providers should direct their patients to reliable material online because patients consider the Internet as an important source of information.

  5. Impacts of beach wrack removal via grooming on surf zone water quality.

    PubMed

    Russell, Todd L; Sassoubre, Lauren M; Zhou, Christina; French-Owen, Darien; Hassaballah, Abdulrahman; Boehm, Alexandria B

    2014-02-18

    Fecal indicator bacteria (FIB) are used to assess the microbial water quality of recreational waters. Increasingly, nonfecal sources of FIB have been implicated as causes of poor microbial water quality in the coastal environment. These sources are challenging to quantify and difficult to remediate. The present study investigates one nonfecal FIB source, beach wrack (decaying aquatic plants), and its impacts on water quality along the Central California coast. The prevalence of FIB on wrack was studied using a multibeach survey, collecting wrack throughout Central California. The impacts of beach grooming, to remove wrack, were investigated at Cowell Beach in Santa Cruz, California using a long-term survey (two summers, one with and one without grooming) and a 48 h survey during the first ever intensive grooming event. FIB were prevalent on wrack but highly variable spatially and temporally along the nine beaches sampled in Central California. Beach grooming was generally associated with either no change or a slight increase in coastal FIB concentrations and increases in surf zone turbidity and silicate, phosphate, and dissolved inorganic nitrogen concentrations. The findings suggest that beach grooming for wrack removal is not justified as a microbial pollution remediation strategy.

  6. GaAs Monolithic Microwave Subsystem Technology Base

    DTIC Science & Technology

    1980-01-01

    To provide a captive source of reliable, high-quality GaAs substrates, a new crystal growth and substrate preparation facility which utilizes a high...Symp. GaAs and Related Compounds, Inst. Phys. Conf. Ser. 24, 6. 20. Wood, Woodcock and Harris (1978) GaAs and Related Compounds, Inst. Phys. Conf

  7. High-Quality Carbohydrates and Physical Performance

    PubMed Central

    Kanter, Mitch

    2018-01-01

    While all experts agreed that protein needs for performance are likely greater than believed in past generations, particularly for strength training athletes, and that dietary fat could sustain an active person through lower-intensity training bouts, current research still points to carbohydrate as an indispensable energy source for high-intensity performance. PMID:29449746

  8. Adaptive Decomposition of Highly Resolved Time Series into Local and Non‐local Components

    EPA Science Inventory

    Highly time-resolved air monitoring data are widely being collected over long time horizons in order to characterizeambient and near-source air quality trends. In many applications, it is desirable to split the time-resolved data into two ormore components (e.g., local and region...

  9. Fast and accurate detection of spread source in large complex networks.

    PubMed

    Paluch, Robert; Lu, Xiaoyan; Suchecki, Krzysztof; Szymański, Bolesław K; Hołyst, Janusz A

    2018-02-06

    Spread over complex networks is a ubiquitous process with increasingly wide applications. Locating spread sources is often important, e.g. finding the patient one in epidemics, or source of rumor spreading in social network. Pinto, Thiran and Vetterli introduced an algorithm (PTVA) to solve the important case of this problem in which a limited set of nodes act as observers and report times at which the spread reached them. PTVA uses all observers to find a solution. Here we propose a new approach in which observers with low quality information (i.e. with large spread encounter times) are ignored and potential sources are selected based on the likelihood gradient from high quality observers. The original complexity of PTVA is O(N α ), where α ∈ (3,4) depends on the network topology and number of observers (N denotes the number of nodes in the network). Our Gradient Maximum Likelihood Algorithm (GMLA) reduces this complexity to O (N 2 log (N)). Extensive numerical tests performed on synthetic networks and real Gnutella network with limitation that id's of spreaders are unknown to observers demonstrate that for scale-free networks with such limitation GMLA yields higher quality localization results than PTVA does.

  10. Decline in Chinese lake phosphorus concentration accompanied by shift in sources since 2006

    NASA Astrophysics Data System (ADS)

    Tong, Yindong; Zhang, Wei; Wang, Xuejun; Couture, Raoul-Marie; Larssen, Thorjørn; Zhao, Yue; Li, Jing; Liang, Huijiao; Liu, Xueyan; Bu, Xiaoge; He, Wei; Zhang, Qianggong; Lin, Yan

    2017-07-01

    Domestic wastewater and agricultural activities are important sources of nutrient pollutants such as phosphorus and nitrogen. Upon reaching freshwater, these nutrients can lead to extensive growth of harmful algae, which results in eutrophication. Many Chinese lakes are subject to such eutrophication, especially in highly polluted areas, and as such, understanding nutrient fluxes to these lakes offers insights into the varying processes governing pollutant fluxes as well as lake water quality. Here we analyse water quality data, recorded between 2006 and 2014 in 862 freshwater lakes in four geographical regions of China, to assess the input of phosphorus from human activity. We find that improvements in sanitation of both rural and urban domestic wastewater have resulted in large-scale declines in lake phosphorus concentrations in the most populated parts of China. In more sparsely populated regions, diffuse sources such as aquaculture and livestock farming offset this decline. Anthropogenic deforestation and soil erosion may also offset decreases in point sources of pollution. In the light of these regional differences, we suggest that a spatially flexible set of policies for water quality control would be beneficial for the future health of Chinese lakes.

  11. 77 FR 18709 - Quality Assurance Requirements for Continuous Opacity Monitoring Systems at Stationary Sources

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-28

    ... Quality Assurance Requirements for Continuous Opacity Monitoring Systems at Stationary Sources AGENCY... direct final rule titled ``Quality Assurance Requirements for Continuous Opacity Monitoring Systems at...--Quality Assurance Requirements for Continuous Opacity Monitoring Systems at Stationary Sources Docket, EPA...

  12. Evaluating the Quality of Colorectal Cancer Care across the Interface of Healthcare Sectors

    PubMed Central

    Ludt, Sabine; Urban, Elisabeth; Eckardt, Jörg; Wache, Stefanie; Broge, Björn; Kaufmann-Kolle, Petra; Heller, Günther; Miksch, Antje; Glassen, Katharina; Hermann, Katja; Bölter, Regine; Ose, Dominik; Campbell, Stephen M.; Wensing, Michel; Szecsenyi, Joachim

    2013-01-01

    Background Colorectal cancer (CRC) has a high prevalence in western countries. Diagnosis and treatment of CRC is complex and requires multidisciplinary collaboration across the interface of health care sectors. In Germany, a new nationwide established program aims to provide quality information of healthcare delivery across different sectors. Within this context, this study describes the development of a set of quality indicators charting the whole pathway of CRC-care including data specifications that are necessary to operationalize these indicators before practice testing. Methods Indicators were developed following a systematic 10 step modified ‘RAND/UCLA Appropriateness Method’ which involved a multidisciplinary panel of thirteen participants. For each indicator in the final set, data specifications relating to sources of quality information, data collection procedures, analysis and feedback were described. Results The final indicator set included 52 indicators covering diagnostic procedures (11 indicators), therapeutic management (28 indicators) and follow-up (6 indicators). In addition, 7 indicators represented patient perspectives. Primary surgical tumor resection and pre-operative radiation (rectum carcinoma only) were perceived as most useful tracer procedures initiating quality data collection. To assess the quality of CRC care across sectors, various data sources were identified: medical records, administrative inpatient and outpatient data, sickness-funds billing code systems and patient survey. Conclusion In Germany, a set of 52 quality indicators, covering necessary aspects across the interfaces and pathways relevant to CRC-care has been developed. Combining different sectors and sources of health care in quality assessment is an innovative and challenging approach but reflects better the reality of the patient pathway and experience of CRC-care. PMID:23658684

  13. Source apportionment analysis of air pollutants using CMAQ/BFM for national air quality management policy over Republic of Korea.

    NASA Astrophysics Data System (ADS)

    Moon, N.; Kim, S.; Seo, J.; Lee, Y. J.

    2017-12-01

    Recently, the Korean government is focusing on solving air pollution problem such as fine particulate matter and ozone. Korea has high population density and concentrated industrial complex in its limited land space. For better air quality management, it is important to understand source and contribution relation to target pollutant. The air quality analysis representing the mutual contribution among the local regions enables to understand the substantive state of the air quality of a region in association with neighboring regions. Under this background, the source apportionment of PM10, PM2.5, O3, NO2, SO2 using WRF and CMAQ/BFM was analyzed over Korea and BFM was applied to mobile, area and point sources in each local government. The contribution rate from neighboring region showed different pattern for each pollutant. In case of primary pollutants such as NO2, SO2, local source contribution is dominant, on the other hand secondary pollutants case especially O3, contribution from neighboring region is higher than that from source region itself. Local source contribution to PM10 showed 20-25% and the contribution rate to O3 has big difference with different meteorological condition year after year. From this study, we tried to estimate the conversion rate between source (NOx, VOC, SO2, NH3, PMC, PM2.5, CO) and concentration (PM10, PM2.5, O3, NO2, SO2,) by regional group over Korea. The result can contribute to the decision-making process of important national planning related to large-scale industrial developments and energy supply policies (eg., operations of coal-fired power plants and diesel cars) and emission control plan, where many controversies and concerns are currently concentrated among local governments in Korea. With this kind of approach, various environmental and social problems related to air quality can also be identified early so that a sustainable and environmentally sound plan can be established by providing data infrastructures to be utilized by central government agencies, local governments, and even private sectors.

  14. Enhancing Leadership Quality. TQ Source Tips & Tools: Emerging Strategies to Enhance Educator Quality

    ERIC Educational Resources Information Center

    National Comprehensive Center for Teacher Quality, 2008

    2008-01-01

    Teaching Quality (TQ) Source Tips & Tools: Emerging Strategies to Enhance Educator Quality is an online resource developed by the TQ Center. It is designed to help education practitioners tap into strategies and resources they can use to enhance educator quality. This publication is based on the TQ Source Tips & Tools topic area "Enhancing…

  15. A Systematic Review of the Level of Evidence in Economic Evaluations of Medical Devices: The Example of Vertebroplasty and Kyphoplasty

    PubMed Central

    van den Brink, Hélène; Pineau, Judith; Prognon, Patrice; Borget, Isabelle

    2015-01-01

    Context Economic evaluations are far less frequently reported for medical devices than for drugs. In addition, little is known about the quality of existing economic evaluations, particularly for innovative devices, such as those used in vertebroplasty and kyphoplasty. Objective To assess the level of evidence provided by the available economic evaluations for vertebroplasty and kyphoplasty. Data Sources A systematic review of articles in English or French listed in the MEDLINE, PASCAL, COCHRANE and National Health Service Economic Evaluation databases, with limits on publication date (up to the date of the review, March 2014). Study Selection We included only economic evaluations of vertebroplasty or kyphoplasty. Editorial and methodological articles were excluded. Data Extraction Data were extracted from articles by two authors working independently and using two analysis grids to measure the quality of economic evaluations. Data Synthesis Twenty-one studies met our inclusion criteria. All were published between 2008 and 2014. Eighteen (86%) were full economic evaluations. Cost-effectiveness analysis (CEA) was the most frequent type of economic evaluation, and was present in 11 (52%) studies. Only three CEAs complied fully with the British Medical Journal checklist. The quality of the data sources used in the 21 studies was high, but the CEAs conforming to methodological guidelines did not use high-quality data sources for all components of the analysis. Conclusions This systematic review shows that the level of evidence in economic evaluations of vertebroplasty and kyphoplasty is low, despite the recent publication of a large number of studies. This finding highlights the challenges to be faced to improve the quality of economic evaluations of medical devices. PMID:26661078

  16. A cutting-edge solution for 1µm laser metal processing

    NASA Astrophysics Data System (ADS)

    Baumbach, N.; Kühl, P.; Karam, J.; Jonkers, J.; Villarreal-Saucedo, F.; Reyes, M.

    2017-02-01

    The recent 1μm-laser cutting market is dominated by fiber and disk lasers due to their excellent beam quality of below 4mm*mrad. Teradiode's 4kW direct diode laser source achieves similar beam quality while having a different beam shape and shorter wavelengths which are known for higher absorption rates at the inclined front of the cutting keyhole. Research projects, such as the HALO Project, have additionally shown that polarized radiation and beams with shapes different from the typical LG00 lead to improved cut quality for ferrous and non-ferrous metals. [1] Diode laser have the inherent property of not being sensitive to back reflection which brings advantages in cutting high-reflective materials. The II-VI HIGHYAG laser cutting head BIMO-FSC offers the unique feature of machine controlled and continuous adjustment of both the focus diameter and the focus position. This feature is proven to be beneficial for cutting and piercing with high speed and small hole diameters. In addition, the optics are designed for lowest focus shift. As a leading laser processing head manufacturer, II-VI HIGHYAG qualified its BIMO-FSC MZ (M=magnification, Z=focus position) cutting head for Teradiode's 4kW direct diode laser source to offer a cutting-edge solution for highpower laser cutting. Combining the magnification ability of the cutting head with this laser source, customers experience strong advantages in cutting metals in broad thickness ranges. Thicknesses up to 25mm mild steel can easily be cut with excellent edge quality. Furthermore, a new optical setup equivalent to an axicon with a variable axicon angle is demonstrated which generates variable sized ring spots. The setup provides new degrees of freedom to tailor the energy distribution for even higher productivity and quality.

  17. Characterization and treatment of water used for human consumption from six sources located in the Cameron/Tuba City abandoned uranium mining area.

    PubMed

    Orescanin, Visnja; Kollar, Robert; Nad, Karlo; Mikelic, Ivanka Lovrencic; Kollar, Iris

    2011-01-01

    The purpose of this research was the characterization and improvement of the quality of water used for human consumption of unregulated/regulated water sources located in the Cameron/Tuba City abandoned uranium mining area (NE Arizona, western edge of the Navajo Nation). Samples were collected at six water sources which included regulated sources: Wind Mill (Tank 3T-538), Badger Springs and Paddock Well as well as unregulated sources: Willy Spring, Water Wall and Water Hole. Samples taken from Wind Mill, Water Wall and Water Hole were characterized with high turbidity and color as well as high level of manganese, iron and nickel and elevated value of molybdenum. High level of iron was also found in Badger Spring, Willy Spring, and Paddock Well. These three water sources were also characterized with elevated values of fluoride and vanadium. Significant amounts of zinc were found in Water Wall and Water Hole samples. Water Wall sample was also characterized with high level of Cr(VI). Compared to primary or secondary Navajo Nation Environmental Protection Agency (NNEPA) water quality standard the highest enrichment was found for turbidity (50.000 times), color (up to 1.796 times) and manganese (71 times), Cr(VI) (17.5 times), iron (7.4 times) and arsenic (5.2 times). Activities of (226)Ra and (238)U in water samples were still in agreement with the maximum contaminant levels. In order to comply with NNEPA water quality standard water samples were subjected to electrochemical treatment. This method was selected due to its high removal efficiency for heavy metals and uranium, lower settlement time, production of smaller volume of waste mud and higher stability of waste mud compared to physico-chemical treatment. Following the treatment, concentrations of heavy metals and activities of radionuclides in all samples were significantly lower compared to NNEPA or WHO regulated values. The maximum removal efficiencies for color, turbidity, arsenic, manganese, molybdenum and nickel were 100.0%. Maximum removal percentage of Cu, F(-), V, Zn, (137)Cs, (226)Ra, (232)Th, (238)U were as follows: 98.0%; 82.7%; 99.9%; 95.6%; 75.0%; 76.9%; 80.0% and 99.2%. From the results presented it could be concluded that electrochemical treatment is a suitable approach for the purification of drinking water with complex mixture of contaminants, especially those with high turbidity and color.

  18. Characterizing Methane Emissions at Local Scales with a 20 Year Total Hydrocarbon Time Series, Imaging Spectrometry, and Web Facilitated Analysis

    NASA Astrophysics Data System (ADS)

    Bradley, Eliza Swan

    Methane is an important greenhouse gas for which uncertainty in local emission strengths necessitates improved source characterizations. Although CH4 plume mapping did not motivate the NASA Airborne Visible InfraRed Imaging Spectrometer (AVIRIS) design and municipal air quality monitoring stations were not intended for studying marine geological seepage, these assets have capabilities that can make them viable for studying concentrated (high flux, highly heterogeneous) CH4 sources, such as the Coal Oil Point (COP) seep field (˜0.015 Tg CH4 yr-1) offshore Santa Barbara, California. Hourly total hydrocarbon (THC) data, spanning 1990 to 2008 from an air pollution station located near COP, were analyzed and showed geologic CH4 emissions as the dominant local source. A band ratio approach was developed and applied to high glint AVIRIS data over COP, resulting in local-scale mapping of natural atmospheric CH4 plumes. A Cluster-Tuned Matched Filter (CTMF) technique was applied to Gulf of Mexico AVIRIS data to detect CH4 venting from offshore platforms. Review of 744 platform-centered CTMF subsets was facilitated through a flexible PHP-based web portal. This dissertation demonstrates the value of investigating municipal air quality data and imaging spectrometry for gathering insight into concentrated methane source emissions and highlights how flexible web-based solutions can help facilitate remote sensing research.

  19. Towards an operational high-resolution air quality forecasting system at ECCC

    NASA Astrophysics Data System (ADS)

    Munoz-Alpizar, Rodrigo; Stroud, Craig; Ren, Shuzhan; Belair, Stephane; Leroyer, Sylvie; Souvanlasy, Vanh; Spacek, Lubos; Pavlovic, Radenko; Davignon, Didier; Moran, Moran

    2017-04-01

    Urban environments are particularly sensitive to weather, air quality (AQ), and climatic conditions. Despite the efforts made in Canada to reduce pollution in urban areas, AQ continues to be a concern for the population, especially during short-term episodes that could lead to exceedances of daily air quality standards. Furthermore, urban air pollution has long been associated with significant adverse health effects. In Canada, the large percentage of the population living in urban areas ( 81%, according to the Canada's 2011 census) is exposed to elevated air pollution due to local emissions sources. Thus, in order to improve the services offered to the Canadian public, Environment and Climate Change Canada has launched an initiative to develop a high-resolution air quality prediction capacity for urban areas in Canada. This presentation will show observed pollution trends (2010-2016) for Canadian mega-cities along with some preliminary high-resolution air quality modelling results. Short-term and long-term plans for urban AQ forecasting in Canada will also be described.

  20. Elevated and super-elevated CO2 differ in their interactive effects with nitrogen availability on fruit yield and quality of cucumber.

    PubMed

    Dong, Jinlong; Xu, Qiao; Gruda, Nazim; Chu, Wenying; Li, Xun; Duan, Zengqiang

    2018-02-25

    Elevated carbon dioxide (CO 2 ) and nitrogen (N) availability can interactively promote cucumber yield, but how the yield increase is realized remains unclear, whilst the interactive effects on fruit quality are unknown. In this study, cucumber plants (Cucumis sativus L. cv. Jinmei No. 3) were grown in a paddy soil under three CO 2 concentrations - 400 (ambient CO 2 ), 800 (elevated CO 2 , eCO 2 ) and 1200 µmol mol -1 (super-elevated CO 2 ) - and two N applications - 0.06 (low N) and 0.24 g N kg -1 soil (high N). Compared with ambient CO 2 , eCO 2 increased yield by 106% in high N but the increase in total biomass was only 33%. This can result from greater carbon translocation to fruits from other organs, indicated by the increased biomass allocation from stems and leaves, particularly source leaves, to fruits and the decreased concentrations of fructose and glucose in source leaves. Super-elevated CO 2 reduced the carbon allocation to fruits thus yield increase (71%). Additionally, eCO 2 also increased the concentrations of fructose and glucose in fruits, maintained the concentrations of dietary fiber, phosphorus, potassium, calcium, magnesium, sulfur, manganese, copper, molybdenum and sodium, whilst it decreased the concentrations of nitrate, protein, iron, and zinc in high N. Compared with eCO 2 , super-elevated CO 2 can still improve the fruit quality to some extent in low N availability. Elevated CO 2 promotes cucumber yield largely by carbon allocation from source leaves to fruits in high N availability. Besides a dilution effect, carbon allocation to fruits, carbohydrate transformation, and nutrient uptake and assimilation can affect the fruit quality. © 2018 Society of Chemical Industry. © 2018 Society of Chemical Industry.

  1. Management of source and drinking-water quality in Pakistan.

    PubMed

    Aziz, J A

    2005-01-01

    Drinking-water quality in both urban and rural areas of Pakistan is not being managed properly. Results of various investigations provide evidence that most of the drinking-water supplies are faecally contaminated. At places groundwater quality is deteriorating due to the naturally occurring subsoil contaminants or to anthropogenic activities. The poor bacteriological quality of drinking-water has frequently resulted in high incidence of waterborne diseases while subsoil contaminants have caused other ailments to consumers. This paper presents a detailed review of drinking-water quality in the country and the consequent health impacts. It identifies various factors contributing to poor water quality and proposes key actions required to ensure safe drinking-water supplies to consumers.

  2. Method for obtaining a collimated near-unity aspect ratio output beam from a DFB-GSE laser with good beam quality.

    PubMed

    Liew, S K; Carlson, N W

    1992-05-20

    A simple method for obtaining a collimated near-unity aspect ratio output beam from laser sources with extremely large (> 100:1) aspect ratios is demonstrated by using a distributed-feedback grating-surfaceemitting laser. Far-field power-in-the-bucket measurements of the laser indicate good beam quality with a high Strehl ratio.

  3. Wilderness, water, and quality of life in the Bitterroot Valley

    Treesearch

    Kari Gunderson; Clint Cook

    2007-01-01

    The Bitterroot Valley is located in western Montana, U.S.A. Most of the Bitterroot Range above the Bitterroot Valley is protected as wilderness, and is a source of much of the water that flows down and through the valley floor. With an annual precipitation of only 12.3 inches, the Bitterroot Valley is classified as a high desert environment. Today the quality of life...

  4. Water supply dynamics and quality of alternative water sources in low-income areas of Lilongwe City, Malawi

    NASA Astrophysics Data System (ADS)

    Chidya, Russel C. G.; Mulwafu, Wapulumuka O.; Banda, Sembeyawo C. T.

    2016-06-01

    Recent studies in many developing countries have shown that Small Scale Independent Providers (SSIPs) in low-income areas (LIAs) are practical alternatives to water utilities. This study explored supply dynamics and quality of alternative water sources in four LIAs of Lilongwe City in Malawi using qualitative and quantitative methods. Household-level surveys (n = 120) and transect walks were employed to determine the socio-economic activities in the areas. One-on-one discussions were made with water source owners (SSIPs) (n = 24). Data on policy and institutional frameworks was collected through desktop study and Key Informant Interviews (n = 25). Quality of the water sources (shallow wells and boreholes) was determined by collecting grab samples (n = 24) in triplicate using 500 mL bottles. Selected physico-chemical and microbiological parameters were measured: pH, EC, TDS, turbidity, water temperature, salinity, K, Na, Ca, Mg, Cl-, F-, NO3-, alkalinity, water hardness, Fecal coliform (FC) and Faecal Streptococci (FS) bacteria. Water quality data was compared with Malawi Bureau of Standards (MBS) and World Health Organization (WHO) guidelines for drinking water. Shallow wells were reported (65%, n = 120) to be the main source of water for household use in all areas. Some policies like prohibition of boreholes and shallow wells in City locations were in conflict with other provisions of water supply, sanitation and housing. High levels of FC (0-2100 cfu/100 mL) and FS (0-1490 cfu/100 mL) at several sites (>90%, n = 24) suggest water contamination likely to impact on human health. This calls for upgrading and recognition of the water sources for improved water service delivery.

  5. [Water quality and personal hygiene in rural areas of Senegal].

    PubMed

    Faye, A; Ndiaye, N M; Faye, D; Tal-Dia, A

    2011-02-01

    The high prevalence of diarrhea in developing countries is mostly due to poor water quality and hygiene practices. The purpose of this study was to assess water quality as well as hygiene practices and their determinants in Ngohé, i.e., a rural community (RC) in Senegal. A combined approach consisting of a cross-sectional descriptive survey and bacterial analysis of water was used. Study was conducted in 312 randomly selected households. Data was collected through individual interviews with the assistance of a guide. Water for bacteriological analysis was collected from various sources, i.e., 3 modem borehole wells, 2 protected wells, and 10 traditional wells. Study points included home water treatment, drinking water source, latrine use, hand washing habits, and bacteria identified in water. A multiple regression model was used for data analysis. The household survey population was 59% male, 61% illiterate, and 93% married. Mean age was 44.8 +/- 18.1 years. Chlorination technique was inadequate in 62% of cases. Latrines were not restricted to adult use in 76% of homes. Hand washing was not performed at critical times in 94%. Drinking water was drawn from traditional wells in 48% of households, modem borehole wells in 45% and protected wells in 7%. Escherichia coli was found in water from all three sources and Vibrio cholerae was found in two traditional wells. Level of education, average monthly income, knowledge about chlorination techniques, and source of the water consumed were the main behavioral determinants (p < 0.05). Water treatment at the source and in the home as well as protection of water sources is necessary to ensure water quality. This will require effective public education campaigns and financial support for improvement of sanitary facilities.

  6. Long-Term Effects of Changing Land Use Practices on Surface Water Quality in a Coastal River and Lagoonal Estuary

    NASA Astrophysics Data System (ADS)

    Rothenberger, Meghan B.; Burkholder, Joann M.; Brownie, Cavell

    2009-09-01

    The watershed of the Neuse River, a major tributary of the largest lagoonal estuary on the U.S. mainland, has sustained rapid growth of human and swine populations. This study integrated a decade of available land cover and water quality data to examine relationships between land use changes and surface water quality. Geographic Information Systems (GIS) analysis was used to characterize 26 subbasins throughout the watershed for changes in land use during 1992-2001, considering urban, agricultural (cropland, animal as pasture, and densities of confined animal feed operations [CAFOs]), forested, grassland, and wetland categories and numbers of wastewater treatment plants (WWTPs). GIS was also used together with longitudinal regression analysis to identify specific land use characteristics that influenced surface water quality. Total phosphorus concentrations were significantly higher during summer in subbasins with high densities of WWTPs and CAFOs. Nitrate was significantly higher during winter in subbasins with high numbers of WWTPs, and organic nitrogen was higher in subbasins with higher agricultural coverage, especially with high coverage of pastures fertilized with animal manure. Ammonium concentrations were elevated after high precipitation. Overall, wastewater discharges in the upper, increasingly urbanized Neuse basin and intensive swine agriculture in the lower basin have been the highest contributors of nitrogen and phosphorus to receiving surface waters. Although nonpoint sources have been emphasized in the eutrophication of rivers and estuaries such as the Neuse, point sources continue to be major nutrient contributors in watersheds sustaining increasing human population growth. The described correlation and regression analyses represent a rapid, reliable method to relate land use patterns to water quality, and they can be adapted to watersheds in any region.

  7. Full field image reconstruction is suitable for high-pitch dual-source computed tomography.

    PubMed

    Mahnken, Andreas H; Allmendinger, Thomas; Sedlmair, Martin; Tamm, Miriam; Reinartz, Sebastian D; Flohr, Thomas

    2012-11-01

    The field of view (FOV) in high-pitch dual-source computed tomography (DSCT) is limited by the size of the second detector. The goal of this study was to develop and evaluate a full FOV image reconstruction technique for high-pitch DSCT. For reconstruction beyond the FOV of the second detector, raw data of the second system were extended to the full dimensions of the first system, using the partly existing data of the first system in combination with a very smooth transition weight function. During the weighted filtered backprojection, the data of the second system were applied with an additional weighting factor. This method was tested for different pitch values from 1.5 to 3.5 on a simulated phantom and on 25 high-pitch DSCT data sets acquired at pitch values of 1.6, 2.0, 2.5, 2.8, and 3.0. Images were reconstructed with FOV sizes of 260 × 260 and 500 × 500 mm. Image quality was assessed by 2 radiologists using a 5-point Likert scale and analyzed with repeated-measure analysis of variance. In phantom and patient data, full FOV image quality depended on pitch. Where complete projection data from both tube-detector systems were available, image quality was unaffected by pitch changes. Full FOV image quality was not compromised at pitch values of 1.6 and remained fully diagnostic up to a pitch of 2.0. At higher pitch values, there was an increasing difference in image quality between limited and full FOV images (P = 0.0097). With this new image reconstruction technique, full FOV image reconstruction can be used up to a pitch of 2.0.

  8. 48 CFR 552.246-70 - Source Inspection by Quality Approved Manufacturer.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Quality Approved Manufacturer. 552.246-70 Section 552.246-70 Federal Acquisition Regulations System... Provisions and Clauses 552.246-70 Source Inspection by Quality Approved Manufacturer. As prescribed in 546.302-70, insert the following clause: Source Inspection by Quality Approved Manufacturer (JUL 09) (a...

  9. 48 CFR 552.246-70 - Source Inspection by Quality Approved Manufacturer.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Quality Approved Manufacturer. 552.246-70 Section 552.246-70 Federal Acquisition Regulations System... Provisions and Clauses 552.246-70 Source Inspection by Quality Approved Manufacturer. As prescribed in 546.302-70, insert the following clause: Source Inspection by Quality Approved Manufacturer (JUL 09) (a...

  10. Homogeneous free-form directional backlight for 3D display

    NASA Astrophysics Data System (ADS)

    Krebs, Peter; Liang, Haowen; Fan, Hang; Zhang, Aiqin; Zhou, Yangui; Chen, Jiayi; Li, Kunyang; Zhou, Jianying

    2017-08-01

    Realization of a near perfect homogeneous secondary emission source for 3D display is proposed and demonstrated. The light source takes advantage of an array of free-form emission surface with a specially tailored light guiding structure, a light diffuser and Fresnel lens. A seamless and homogeneous directional emission is experimentally obtained which is essential for a high quality naked-eye 3D display.

  11. Finding Funding: A Guide to Federal Sources for Out-of-School TIme and Community School Initiatives. Revised and Updated.

    ERIC Educational Resources Information Center

    Padgette, Heather Clapp

    Noting the growing nation-wide demand for affordable, high-quality, out-of-school time and community school programs, this guide is intended to assist program developers, policy makers, and community leaders identify federal funding sources to support out-of-school time or broader-based community school services. The guide provides an overview of…

  12. The interaction between reproductive cost and individual quality is mediated by oceanic conditions in a long-lived bird.

    PubMed

    Robert, Alexandre; Paiva, Vitor H; Bolton, Mark; Jiguet, Frédéric; Bried, Joël

    2012-08-01

    Environmental variability, costs of reproduction, and heterogeneity in individual quality are three important sources of the temporal and interindividual variations in vital rates of wild populations. Based on an 18-year monitoring of an endangered, recently described, long-lived seabird, Monteiro's Storm-Petrel (Oceanodroma monteiroi), we designed multistate survival models to separate the effects of the reproductive cost (breeders vs. nonbreeders) and individual quality (successful vs. unsuccessful breeders) in relation to temporally variable demographic and oceanographic properties. The analysis revealed a gradient of individual quality from nonbreeders, to unsuccessful breeders, to successful breeders. The survival rates of unsuccessful breeders (0.90 +/- 0.023, mean +/- SE) tended to decrease in years of high average breeding success and were more sensitive to oceanographic variation than those of both (high-quality) successful breeders (0.97 +/- 0.015) and (low-quality) nonbreeders (0.83 +/- 0.028). Overall, our results indicate that reproductive costs act on individuals of intermediate quality and are mediated by environmental harshness.

  13. In-time source tracking of watershed loads of Taihu Lake Basin, China based on spatial relationship modeling.

    PubMed

    Wang, Ce; Bi, Jun; Zhang, Xu-Xiang; Fang, Qiang; Qi, Yi

    2018-05-25

    Influent river carrying cumulative watershed load plays a significant role in promoting nuisance algal bloom in river-fed lake. It is most relevant to discern in-stream water quality exceedance and evaluate the spatial relationship between risk location and potential pollution sources. However, no comprehensive studies of source tracking in watershed based on management grid have been conducted for refined water quality management, particularly for plain terrain with complex river network. In this study, field investigations were implemented during 2014 in Taige Canal watershed of Taihu Lake Basin. A Geographical Information System (GIS)-based spatial relationship model was established to characterize the spatial relationships of "point (point-source location and monitoring site)-line (river segment)-plane (catchment)." As a practical exemplification, in-time source tracking was triggered on April 15, 2015 at Huangnianqiao station, where TN and TP concentration violated the water quality standard (TN 4.0 mg/L, TP 0.15 mg/L). Of the target grid cells, 53 and 46 were identified as crucial areas having high pollution intensity for TN and TP pollution, respectively. The estimated non-point source load in each grid cell could be apportioned into different source types based on spatial pollution-related entity objects. We found that the non-point source load derived from rural sewage and livestock and poultry breeding accounted for more than 80% of total TN or TP load than another source type of crop farming. The approach in this study would be of great benefit to local authorities for identifying the serious polluted regions and efficiently making environmental policies to reduce watershed load.

  14. Water Quality Monitoring in Developing Countries; Can Microbial Fuel Cells be the Answer?

    PubMed Central

    Chouler, Jon; Di Lorenzo, Mirella

    2015-01-01

    The provision of safe water and adequate sanitation in developing countries is a must. A range of chemical and biological methods are currently used to ensure the safety of water for consumption. These methods however suffer from high costs, complexity of use and inability to function onsite and in real time. The microbial fuel cell (MFC) technology has great potential for the rapid and simple testing of the quality of water sources. MFCs have the advantages of high simplicity and possibility for onsite and real time monitoring. Depending on the choice of manufacturing materials, this technology can also be highly cost effective. This review covers the state-of-the-art research on MFC sensors for water quality monitoring, and explores enabling factors for their use in developing countries. PMID:26193327

  15. Water Quality Monitoring in Developing Countries; Can Microbial Fuel Cells be the Answer?

    PubMed

    Chouler, Jon; Di Lorenzo, Mirella

    2015-07-16

    The provision of safe water and adequate sanitation in developing countries is a must. A range of chemical and biological methods are currently used to ensure the safety of water for consumption. These methods however suffer from high costs, complexity of use and inability to function onsite and in real time. The microbial fuel cell (MFC) technology has great potential for the rapid and simple testing of the quality of water sources. MFCs have the advantages of high simplicity and possibility for onsite and real time monitoring. Depending on the choice of manufacturing materials, this technology can also be highly cost effective. This review covers the state-of-the-art research on MFC sensors for water quality monitoring, and explores enabling factors for their use in developing countries.

  16. Reconnaissance of water-quality characteristics of streams in the City of Charlotte and Mecklenburg County, North Carolina

    USGS Publications Warehouse

    Eddins, W.H.; Crawford, J.K.

    1984-01-01

    In 1979-81, water samples were collected from 119 sites on streams throughout the City of Charlotte and Mecklenburg County, North Carolina, and were analyzed for specific conductance, dissolved chloride, hardness, pH, total alkalinity, total phosphorus, trace elements, arsenic, cadmium, chromium, copper, iron, lead, manganese, mercury, silver, and zinc and biological measures including dissolved oxygen, biochemical oxygen demand, fecal coliform bacteria, and fecal streptococcus bacteria. Sampling was conducted during both low flow (base flow) and high flow. Several water-quality measures including pH, total arsenic, total cadmium, total chromium, total copper, total iron, total lead, total manganese, total mercury, total silver, total zinc, dissolved oxygen, and fecal coliform bacteria at times exceeded North Carolina water-quality standards in various streams. Runoff from non-point sources appears to contribute more to the deterioration of streams in Charlotte and Mecklenburg County than point-source effluents. Urban and industrial areas contribute various trace elements. Residential and rural areas and municipal waste-water treatment plants contribute high amounts of phosphorus.

  17. Narrow bandwidth Laser-Plasma Accelerator driven Thomson photon source development

    NASA Astrophysics Data System (ADS)

    Geddes, C. G. R.; Tsai, H.-E.; Otero, G.; Liu, X.; van Tilborg, J.; Toth, Cs.; Vay, J.-L.; Lehe, R.; Schroeder, C. B.; Esarey, E.; Friedman, A.; Grote, D. P.; Leemans, W. P.

    2017-10-01

    Compact, high-quality photon sources at MeV energies can be provided by Thomson scattering of a laser from the electron beam of a Laser-Plasma Accelerator (LPA). Recent experiments and simulations demonstrate controllable LPAs in the energy range appropriate to MeV sources. Simulations indicate that high flux with narrow energy spread can be achieved via control of the scattering laser pulse shape and laser guiding, and that undesired background bremsstrahlung can be mitigated by plasma based deceleration of the electron beam after photon production. Construction of experiments and laser capabilities to combine these elements will be presented, along with initial operations, towards a compact photon source system. Work supported by US DOE NNSA DNN R&D and by Sc. HEP under contract DE-AC02-05CH11231.

  18. The enigma of aluminum deposition in bone tissue from a patient with chronic kidney disease: a case report.

    PubMed

    Meira, Rodrigo Dias de; Carbonara, Cinthia Esbrile Moraes; Quadros, Kélcia Rosana da Silva; Santos, Carolina Urbini Dos; Schincariol, Patrícia; Pêssoa, Gustavo de Souza; Arruda, Marco Aurélio Zezzi; Jorgetti, Vanda; Oliveira, Rodrigo Bueno de

    2018-06-04

    About four decades ago, the relationship between dialysis-dementia and aluminum (Al) began to be established. The restriction of drugs containing Al and improvements on water quality used for dialysis resulted in the clinical disappearance of Al intoxication. However, high prevalence of Al deposition in bone tissue from Brazilian dialysis patients is still being detected. Through the case report of a patient on hemodialysis (HD) for one year, presenting significant Al deposition in bone tissue, we speculated if this problem is not being underestimated. We used extensive investigation to identify potential sources of Al exposure with a careful review of medication history and water quality controls. Al concentration was measured by different methods, including mass spectrometry, in poly-electrolyte concentrate solutions and solution for peritoneal dialysis, in an attempt to elucidate the possible sources of contamination. The objective of this case report is to alert the medical community about a potential high prevalence of Al deposition in bone tissue and to discuss the possible sources of contamination in patients with chronic kidney disease (CKD).

  19. Beam brilliance investigation of high current ion beams at GSI heavy ion accelerator facility.

    PubMed

    Adonin, A A; Hollinger, R

    2014-02-01

    In this work the emittance measurements of high current Ta-beam provided by VARIS (Vacuum Arc Ion Source) ion source are presented. Beam brilliance as a function of beam aperture at various extraction conditions is investigated. Influence of electrostatic ion beam compression in post acceleration gap on the beam quality is discussed. Use of different extraction systems (single aperture, 7 holes, and 13 holes) in order to achieve more peaked beam core is considered. The possible ways to increase the beam brilliance are discussed.

  20. Complementary metal-oxide semiconductor compatible source of single photons at near-visible wavelengths

    NASA Astrophysics Data System (ADS)

    Cernansky, Robert; Martini, Francesco; Politi, Alberto

    2018-02-01

    We demonstrate on chip generation of correlated pairs of photons in the near-visible spectrum using a CMOS compatible PECVD Silicon Nitride photonic device. Photons are generated via spontaneous four wave mixing enhanced by a ring resonator with high quality Q-factor of 320,000 resulting in a generation rate of 950,000 $\\frac{pairs}{mW}$. The high brightness of this source offers the opportunity to expand photonic quantum technologies over a broad wavelength range and provides a path to develop fully integrated quantum chips working at room temperature.

  1. Sequence independent amplification of DNA

    DOEpatents

    Bohlander, S.K.

    1998-03-24

    The present invention is a rapid sequence-independent amplification procedure (SIA). Even minute amounts of DNA from various sources can be amplified independent of any sequence requirements of the DNA or any a priori knowledge of any sequence characteristics of the DNA to be amplified. This method allows, for example, the sequence independent amplification of microdissected chromosomal material and the reliable construction of high quality fluorescent in situ hybridization (FISH) probes from YACs or from other sources. These probes can be used to localize YACs on metaphase chromosomes but also--with high efficiency--in interphase nuclei. 25 figs.

  2. Sequence independent amplification of DNA

    DOEpatents

    Bohlander, Stefan K.

    1998-01-01

    The present invention is a rapid sequence-independent amplification procedure (SIA). Even minute amounts of DNA from various sources can be amplified independent of any sequence requirements of the DNA or any a priori knowledge of any sequence characteristics of the DNA to be amplified. This method allows, for example the sequence independent amplification of microdissected chromosomal material and the reliable construction of high quality fluorescent in situ hybridization (FISH) probes from YACs or from other sources. These probes can be used to localize YACs on metaphase chromosomes but also--with high efficiency--in interphase nuclei.

  3. Single Quantum Dot with Microlens and 3D-Printed Micro-objective as Integrated Bright Single-Photon Source

    PubMed Central

    2017-01-01

    Integrated single-photon sources with high photon-extraction efficiency are key building blocks for applications in the field of quantum communications. We report on a bright single-photon source realized by on-chip integration of a deterministic quantum dot microlens with a 3D-printed multilens micro-objective. The device concept benefits from a sophisticated combination of in situ 3D electron-beam lithography to realize the quantum dot microlens and 3D femtosecond direct laser writing for creation of the micro-objective. In this way, we obtain a high-quality quantum device with broadband photon-extraction efficiency of (40 ± 4)% and high suppression of multiphoton emission events with g(2)(τ = 0) < 0.02. Our results highlight the opportunities that arise from tailoring the optical properties of quantum emitters using integrated optics with high potential for the further development of plug-and-play fiber-coupled single-photon sources. PMID:28670600

  4. The impact of realistic source shape and flexibility on source mask optimization

    NASA Astrophysics Data System (ADS)

    Aoyama, Hajime; Mizuno, Yasushi; Hirayanagi, Noriyuki; Kita, Naonori; Matsui, Ryota; Izumi, Hirohiko; Tajima, Keiichi; Siebert, Joachim; Demmerle, Wolfgang; Matsuyama, Tomoyuki

    2013-04-01

    Source mask optimization (SMO) is widely used to make state-of-the-art semiconductor devices in high volume manufacturing. To realize mature SMO solutions in production, the Intelligent Illuminator, which is an illumination system on Nikon scanner, is useful because it can provide generation of freeform sources with high fidelity to the target. Proteus SMO, which employs co-optimization method and an insertion of validation with mask 3D effect and resist properties for an accurate prediction of wafer printing, can take into account the properties of Intelligent Illuminator. We investigate an impact of the source properties on the SMO to pattern of a static-random access memory. Quality of a source made on the scanner compared to the SMO target is evaluated with in-situ measurement and aerial image simulation using its measurement data. Furthermore we discuss an evaluation of a universality of the source to use it in multiple scanners with a validation with estimated value of scanner errors.

  5. The Rise of Big Data in Oncology.

    PubMed

    Fessele, Kristen L

    2018-05-01

    To describe big data and data science in the context of oncology nursing care. Peer-reviewed and lay publications. The rapid expansion of real-world evidence from sources such as the electronic health record, genomic sequencing, administrative claims and other data sources has outstripped the ability of clinicians and researchers to manually review and analyze it. To promote high-quality, high-value cancer care, big data platforms must be constructed from standardized data sources to support extraction of meaningful, comparable insights. Nurses must advocate for the use of standardized vocabularies and common data elements that represent terms and concepts that are meaningful to patient care. Copyright © 2018 Elsevier Inc. All rights reserved.

  6. Light sources based on semiconductor current filaments

    DOEpatents

    Zutavern, Fred J.; Loubriel, Guillermo M.; Buttram, Malcolm T.; Mar, Alan; Helgeson, Wesley D.; O'Malley, Martin W.; Hjalmarson, Harold P.; Baca, Albert G.; Chow, Weng W.; Vawter, G. Allen

    2003-01-01

    The present invention provides a new type of semiconductor light source that can produce a high peak power output and is not injection, e-beam, or optically pumped. The present invention is capable of producing high quality coherent or incoherent optical emission. The present invention is based on current filaments, unlike conventional semiconductor lasers that are based on p-n junctions. The present invention provides a light source formed by an electron-hole plasma inside a current filament. The electron-hole plasma can be several hundred microns in diameter and several centimeters long. A current filament can be initiated optically or with an e-beam, but can be pumped electrically across a large insulating region. A current filament can be produced in high gain photoconductive semiconductor switches. The light source provided by the present invention has a potentially large volume and therefore a potentially large energy per pulse or peak power available from a single (coherent) semiconductor laser. Like other semiconductor lasers, these light sources will emit radiation at the wavelength near the bandgap energy (for GaAs 875 nm or near infra red). Immediate potential applications of the present invention include high energy, short pulse, compact, low cost lasers and other incoherent light sources.

  7. An assessment of optical properties of dissolved organic material as quantitative source indicators in the Santa Ana River basin, Southern California

    USGS Publications Warehouse

    Bergamaschi, Brian A.; Kalve, Erica; Guenther, Larry; Mendez, Gregory O.; Belitz, Kenneth

    2005-01-01

    The ability to rapidly, reliably, and inexpensively characterize sources of dissolved organic material (DOM) in watersheds would allow water management agencies to more quickly identify problems in water sources, and to more efficiently allocate water resources by, for example, permitting real-time identification of high-quality water suitable for ground-water recharge, or poor-quality water in need of mitigation. This study examined the feasibility of using easily measurable intrinsic optical properties' absorbance and fluorescence spectra, as quantitative indicators of DOM sources and, thus, a predictor of water quality. The study focused on the Santa Ana River Basin, in southern California, USA, which comprises an area of dense urban development and an area of intense dairy production. Base flow in the Santa Ana Basin is primarily tertiary treated wastewater discharge. Available hydrologic data indicate that urban and agricultural runoff degrades water quality during storm events by introducing pathogens, nutrients, and other contaminants, including significant amounts of DOM. These conditions provide the basis for evaluating the use of DOM optical properties as a tracer of DOM from different sources. Sample spectra representing four principal DOM sources were identified among all samples collected in 1999 on the basis of basin hydrology, and the distribution of spectral variability within all the sample data. A linear mixing model provided quantitative estimates of relative endmember contribution to sample spectra for monthly, storm, and diurnal samples. The spectral properties of the four sources (endmembers), Pristine Water, Wastewater, Urban Water, and Dairy Water, accounted for 94 percent of the variability in optical properties observed in the study, suggesting that all important DOM sources were represented. The scale and distribution of the residual spectra, that not explained by the endmembers, suggested that the endmember spectra selected did not adequately represent Urban Water base flow. However, model assignments of sources generally agreed well with those expected, based on sampling location and hydrology. The results suggest that with a fuller characterization of the endmember spectra, analysis of optical properties will provide rapid quantitative estimates of the relative contribution of DOM sources in the Santa Ana Basin.

  8. A Strategy for Federal Science and Technology to Support Water Availability and Quality in the United States

    DTIC Science & Technology

    2007-09-01

    Subcommittee on Water Availability and Quality Microbial source tracking to identify the source of fecal contamination Many of the Nation’s resource...water- quality health standards. In addition, identi- fication of fecal sources is relevant to source-water protection programs and to the development...estuaries, snowpack, and soil . • Develop sensors and systems to measure water quality inexpensively in real time. Develop innovative water-use technologies

  9. High Res at High Speed: Automated Delivery of High-Resolution Images from Digital Library Collections

    ERIC Educational Resources Information Center

    Westbrook, R. Niccole; Watkins, Sean

    2012-01-01

    As primary source materials in the library are digitized and made available online, the focus of related library services is shifting to include new and innovative methods of digital delivery via social media, digital storytelling, and community-based and consortial image repositories. Most images on the Web are not of sufficient quality for most…

  10. Evaluation of Streamflow, Water Quality, and Permitted and Nonpermitted Loads and Yields in the Raritan River Basin, New Jersey, Water Years 1991-98

    USGS Publications Warehouse

    Reiser, Robert G.

    2003-01-01

    Seventeen water-quality constituents were analyzed in samples collected from 21 surface-water sampling sites in the Raritan River Basin during water years 1991-97. Loads were computed for seven constituents. Thirteen constituents have associated instream water-quality standards that are used as reference levels when evaluating the data. Nine of the 13 constituents did not meet water-quality reference levels in all samples at all sites. The constituents that most commonly failed to meet the water-quality reference levels in the 801 samples analyzed were total phosphorus (greater than 0.1 mg/L (milligrams per liter) in 32 percent of samples), fecal coliform bacteria (greater than 400 counts/100 milliliters in 29 percent), hardness (less than 50 mg/L in 21 percent), pH (greater than 8.5 or less than 6.5 in 17 percent), and water temperature in designated trout waters (greater than 20 degrees Celsius in 12 percent of samples). Concentrations of chloride, total dissolved solids, nitrate plus nitrite, and sulfate did not exceed water-quality reference levels in any sample. Results from previous studies on pesticides and volatile organic compounds in streamwater during 1996-98, and organic compounds and trace elements in sediments during 1976-93, were summarized for this study. Concentrations of pesticides in some samples exceeded the relevant standards. Water-quality data varied significantly as season and streamflow changed. Concentrations or values of 12 constituents were significantly higher in the growing season than in the nongrowing season at 1 to 21 sites, and concentrations of 6 constituents were significantly higher in the nongrowing season at 1 to 21 sites. Concentrations or values of seven constituents decreased significantly with increased streamflow, indicating a more significant contribution from base flow or permitted sources than from runoff. Concentrations or values of four constituents increased with increased flow, indicating a more significant contribution from runoff than from base flow or permitted sources. Phosphorus concentrations increased with flow at two sites with no point sources and decreased with flow at five sites with four or more permitted point sources. Concentrations of five constituents did not vary significantly with changes in streamflow at any of the sites. Concentrations of constituents differed significantly between sites. The sites with the most desirable values for the most constituents were Mulhockaway Creek, Spruce Run, Millstone River at Manalapan, Manalapan Brook, and Lamington River at Pottersville. The sites with the least desirable values for the most constituents were Millstone River at Blackwells Mills, Matchaponix Brook, Raritan River at Bound Brook, Neshanic River, and Millstone River at Grovers Mill. The total instream loads of seven constituents - total ammonia plus organic nitrogen (TKN), biochemical oxygen demand (BOD), total dissolved solids (TDS), nitrate plus nitrite (NO3+NO2), total organic carbon (TOC), total phosphorus, and total suspended solids (TSS) - were analyzed at low, median, and high flows. The quantities of total instream load that originated from facilities with permits issued by the New Jersey Department of Environmental Protection to discharge effluent to streams (permitted sources) and from other sources (nonpermitted sources) were estimated for each sampling site. TOC and TSS loads primarily were contributed by nonpermitted sources at all flows. BOD and TDS loads primarily were contributed by nonpermitted sources at median and high flows. At low flow, permitted sources contributed more than one-third of the TDS load at 10 sites and more than one-third of the BOD load at 3 sites. Permitted sources contributed more than one-third of the total phosphorus load at 15 and 14 sites at low and median flows, respectively. Permitted sources accounted for more than one-third of total instream load of NO3+NO2 at low- and median-flow conditions at nearly

  11. Monitoring Error Rates In Illumina Sequencing.

    PubMed

    Manley, Leigh J; Ma, Duanduan; Levine, Stuart S

    2016-12-01

    Guaranteeing high-quality next-generation sequencing data in a rapidly changing environment is an ongoing challenge. The introduction of the Illumina NextSeq 500 and the depreciation of specific metrics from Illumina's Sequencing Analysis Viewer (SAV; Illumina, San Diego, CA, USA) have made it more difficult to determine directly the baseline error rate of sequencing runs. To improve our ability to measure base quality, we have created an open-source tool to construct the Percent Perfect Reads (PPR) plot, previously provided by the Illumina sequencers. The PPR program is compatible with HiSeq 2000/2500, MiSeq, and NextSeq 500 instruments and provides an alternative to Illumina's quality value (Q) scores for determining run quality. Whereas Q scores are representative of run quality, they are often overestimated and are sourced from different look-up tables for each platform. The PPR's unique capabilities as a cross-instrument comparison device, as a troubleshooting tool, and as a tool for monitoring instrument performance can provide an increase in clarity over SAV metrics that is often crucial for maintaining instrument health. These capabilities are highlighted.

  12. Assessing race and ethnicity data quality across cancer registries and EMRs in two hospitals.

    PubMed

    Lee, Simon J Craddock; Grobe, James E; Tiro, Jasmin A

    2016-05-01

    Measurement of patient race/ethnicity in electronic health records is mandated and important for tracking health disparities. Characterize the quality of race/ethnicity data collection efforts. For all cancer patients diagnosed (2007-2010) at two hospitals, we extracted demographic data from five sources: 1) a university hospital cancer registry, 2) a university electronic medical record (EMR), 3) a community hospital cancer registry, 4) a community EMR, and 5) a joint clinical research registry. The patients whose data we examined (N = 17 834) contributed 41 025 entries (range: 2-5 per patient across sources), and the source comparisons generated 1-10 unique pairs per patient. We used generalized estimating equations, chi-squares tests, and kappas estimates to assess data availability and agreement. Compared to sex and insurance status, race/ethnicity information was significantly less likely to be available (χ(2 )> 8043, P < .001), with variation across sources (χ(2 )> 10 589, P < .001). The university EMR had a high prevalence of "Unknown" values. Aggregate kappa estimates across the sources was 0.45 (95% confidence interval, 0.45-0.45; N = 31 276 unique pairs), but improved in sensitivity analyses that excluded the university EMR source (κ = 0.89). Race/ethnicity data were in complete agreement for only 6988 patients (39.2%). Pairs with a "Black" data value in one of the sources had the highest agreement (95.3%), whereas pairs with an "Other" value exhibited the lowest agreement across sources (11.1%). Our findings suggest that high-quality race/ethnicity data are attainable. Many of the "errors" in race/ethnicity data are caused by missing or "Unknown" data values. To facilitate transparent reporting of healthcare delivery outcomes by race/ethnicity, healthcare systems need to monitor and enforce race/ethnicity data collection standards. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  13. Detection of ricin contamination in ground beef by electrochemiluminescence immunosorbent assay

    USDA-ARS?s Scientific Manuscript database

    Ricin is a highly toxic protein present in the seeds of Ricinus communis (castor), grown principally as a source of high quality industrial lubricant and as an ornamental. Because ricin has been used for intentional poisoning in the past and could be used to contaminate food, there is a need for ana...

  14. Genetic diversity in peach [Prunus persica (L.) Batsch] at the University of Florida: past present and future

    USDA-ARS?s Scientific Manuscript database

    The University of Florida (UF) stone fruit breeding and genetics program was created in 1952 to develop early ripening stone fruit cultivars with high quality, adaptation to summer rainfall, low chilling requirements, and the ability to withstand high disease pressure. Diverse germplasm sources were...

  15. Development and Validation of a High-Quality Composite Real-World Mortality Endpoint.

    PubMed

    Curtis, Melissa D; Griffith, Sandra D; Tucker, Melisa; Taylor, Michael D; Capra, William B; Carrigan, Gillis; Holzman, Ben; Torres, Aracelis Z; You, Paul; Arnieri, Brandon; Abernethy, Amy P

    2018-05-14

    To create a high-quality electronic health record (EHR)-derived mortality dataset for retrospective and prospective real-world evidence generation. Oncology EHR data, supplemented with external commercial and US Social Security Death Index data, benchmarked to the National Death Index (NDI). We developed a recent, linkable, high-quality mortality variable amalgamated from multiple data sources to supplement EHR data, benchmarked against the highest completeness U.S. mortality data, the NDI. Data quality of the mortality variable version 2.0 is reported here. For advanced non-small-cell lung cancer, sensitivity of mortality information improved from 66 percent in EHR structured data to 91 percent in the composite dataset, with high date agreement compared to the NDI. For advanced melanoma, metastatic colorectal cancer, and metastatic breast cancer, sensitivity of the final variable was 85 to 88 percent. Kaplan-Meier survival analyses showed that improving mortality data completeness minimized overestimation of survival relative to NDI-based estimates. For EHR-derived data to yield reliable real-world evidence, it needs to be of known and sufficiently high quality. Considering the impact of mortality data completeness on survival endpoints, we highlight the importance of data quality assessment and advocate benchmarking to the NDI. © 2018 The Authors. Health Services Research published by Wiley Periodicals, Inc. on behalf of Health Research and Educational Trust.

  16. Nitrogen Dioxide's Impact on Indoor Air Quality

    EPA Pesticide Factsheets

    The two most prevalent oxides of nitrogen are nitrogen dioxide (NO2) and nitric oxide (NO). Both are toxic gases with NO2 being a highly reactive oxidant and corrosive. The primary sources indoors are combustion processes.

  17. Geodynamics branch data base for main magnetic field analysis

    NASA Technical Reports Server (NTRS)

    Langel, Robert A.; Baldwin, R. T.

    1991-01-01

    The data sets used in geomagnetic field modeling at GSFC are described. Data are measured and obtained from a variety of information and sources. For clarity, data sets from different sources are categorized and processed separately. The data base is composed of magnetic observatory data, surface data, high quality aeromagnetic, high quality total intensity marine data, satellite data, and repeat data. These individual data categories are described in detail in a series of notebooks in the Geodynamics Branch, GSFC. This catalog reviews the original data sets, the processing history, and the final data sets available for each individual category of the data base and is to be used as a reference manual for the notebooks. Each data type used in geomagnetic field modeling has varying levels of complexity requiring specialized processing routines for satellite and observatory data and two general routines for processing aeromagnetic, marine, land survey, and repeat data.

  18. Methods for making deposited films with improved microstructures

    DOEpatents

    Patten, James W.; Moss, Ronald W.; McClanahan, Edwin D.

    1982-01-01

    Methods for improving microstructures of line-of-sight deposited films are described. Columnar growth defects ordinarily produced by geometrical shadowing during deposition of such films are eliminated without resorting to post-deposition thermal or mechanical treatments. The native, as-deposited coating qualities, including homogeneity, fine grain size, and high coating-to-substrate adherence, can thus be retained. The preferred method includes the steps of emitting material from a source toward a substrate to deposit a coating non-uniformly on the substrate surface, removing a portion of the coating uniformly over the surface, again depositing material onto the surface, but from a different direction, and repeating the foregoing steps. The quality of line-of-sight deposited films such as those produced by sputtering, progressively deteriorates as the angle of incidence between the flux and the surface becomes increasingly acute. Depositing non-uniformly, so that the coating becomes progressively thinner as quality deteriorates, followed by uniformly removing some of the coating, such as by resputtering, eliminates the poor quality portions, leaving only high quality portions of the coating. Subsequently sputtering from a different direction applies a high quality coating to other regions of the surface. Such steps can be performed either simultaneously or sequentially to apply coatings of a uniformly high quality, closed microstructure to three-dimensional or larger planar surfaces.

  19. Deposited films with improved microstructures

    DOEpatents

    Patten, James W.; Moss, Ronald W.; McClanahan, Edwin D.

    1984-01-01

    Methods for improving microstructures of line-of-sight deposited films are described. Columnar growth defects ordinarily produced by geometrical shadowing during deposition of such films are eliminated without resorting to post-deposition thermal or mechanical treatments. The native, as-deposited coating qualities, including homogeneity, fine grain size, and high coating-to-substrate adherence, can thus be retained. The preferred method includes the steps of emitting material from a source toward a substrate to deposit a coating non-uniformly on the substrate surface, removing a portion of the coating uniformly over the surface, again depositing material onto the surface, but from a different direction, and repeating the foregoing steps. The quality of line-of-sight deposited films such as those produced by sputtering, progressively deteriorates as the angle of incidence between the flux and the surface becomes increasingly acute. Depositing non-uniformly, so that the coating becomes progressively thinner as quality deteriorates, followed by uniformly removing some of the coating, such as by resputtering, eliminates the poor quality portions, leaving only high quality portions of the coating. Subsequently sputtering from a different direction applies a high quality coating to other regions of the surface. Such steps can be performed either simultaneously or sequentially to apply coatings of a uniformly high quality, closed microstructure to three-dimensional or large planar surfaces.

  20. Contaminant point source localization error estimates as functions of data quantity and model quality

    NASA Astrophysics Data System (ADS)

    Hansen, Scott K.; Vesselinov, Velimir V.

    2016-10-01

    We develop empirically-grounded error envelopes for localization of a point contamination release event in the saturated zone of a previously uncharacterized heterogeneous aquifer into which a number of plume-intercepting wells have been drilled. We assume that flow direction in the aquifer is known exactly and velocity is known to within a factor of two of our best guess from well observations prior to source identification. Other aquifer and source parameters must be estimated by interpretation of well breakthrough data via the advection-dispersion equation. We employ high performance computing to generate numerous random realizations of aquifer parameters and well locations, simulate well breakthrough data, and then employ unsupervised machine optimization techniques to estimate the most likely spatial (or space-time) location of the source. Tabulating the accuracy of these estimates from the multiple realizations, we relate the size of 90% and 95% confidence envelopes to the data quantity (number of wells) and model quality (fidelity of ADE interpretation model to actual concentrations in a heterogeneous aquifer with channelized flow). We find that for purely spatial localization of the contaminant source, increased data quantities can make up for reduced model quality. For space-time localization, we find similar qualitative behavior, but significantly degraded spatial localization reliability and less improvement from extra data collection. Since the space-time source localization problem is much more challenging, we also tried a multiple-initial-guess optimization strategy. This greatly enhanced performance, but gains from additional data collection remained limited.

  1. Impacts of Energy Sector Emissions on PM2.5 Air Quality in Northern India

    NASA Astrophysics Data System (ADS)

    Karambelas, A. N.; Kiesewetter, G.; Heyes, C.; Holloway, T.

    2015-12-01

    India experiences high concentrations of fine particulate matter (PM2.5), and several Indian cities currently rank among the world's most polluted cities. With ongoing urbanization and a growing economy, emissions from different energy sectors remain major contributors to air pollution in India. Emission sectors impact ambient air quality differently due to spatial distribution (typical urban vs. typical rural sources) as well as source height characteristics (low-level vs. high stack sources). This study aims to assess the impacts of emissions from three distinct energy sectors—transportation, domestic, and electricity—on ambient PM2.5­­ in northern India using an advanced air quality analysis framework based on the U.S. EPA Community Multi-Scale Air Quality (CMAQ) model. Present air quality conditions are simulated using 2010 emissions from the Greenhouse Gas-Air Pollution Interaction and Synergies (GAINS) model. Modeled PM2.5 concentrations are compared with satellite observations of aerosol optical depth (AOD) from the Moderate Imaging Spectroradiometer (MODIS) for 2010. Energy sector emissions impacts on future (2030) PM2.5 are evaluated with three sensitivity simulations, assuming maximum feasible reduction technologies for either transportation, domestic, or electricity sectors. These simulations are compared with a business as usual 2030 simulation to assess relative sectoral impacts spatially and temporally. CMAQ is modeled at 12km by 12km and include biogenic emissions from the Community Land Model coupled with the Model of Emissions of Gases and Aerosols in Nature (CLM-MEGAN), biomass burning emissions from the Global Fires Emissions Database (GFED), and ERA-Interim meteorology generated with the Weather Research and Forecasting (WRF) model for 2010 to quantify the impact of modified anthropogenic emissions on ambient PM2.5 concentrations. Energy sector emissions analysis supports decision-making to improve future air quality and public health in India.

  2. A multilevel reuse system with source separation process for printing and dyeing wastewater treatment: A case study.

    PubMed

    Wang, Rui; Jin, Xin; Wang, Ziyuan; Gu, Wantao; Wei, Zhechao; Huang, Yuanjie; Qiu, Zhuang; Jin, Pengkang

    2018-01-01

    This paper proposes a new system of multilevel reuse with source separation in printing and dyeing wastewater (PDWW) treatment in order to dramatically improve the water reuse rate to 35%. By analysing the characteristics of the sources and concentrations of pollutants produced in different printing and dyeing processes, special, highly, and less contaminated wastewaters (SCW, HCW, and LCW, respectively) were collected and treated separately. Specially, a large quantity of LCW was sequentially reused at multiple levels to meet the water quality requirements for different production processes. Based on this concept, a multilevel reuse system with a source separation process was established in a typical printing and dyeing enterprise. The water reuse rate increased dramatically to 62%, and the reclaimed water was reused in different printing and dyeing processes based on the water quality. This study provides promising leads in water management for wastewater reclamation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Photochemical Grid Modelling Study to Assess Potential Air Quality Impacts Associated with Energy Development in Colorado and Northern New Mexico.

    NASA Astrophysics Data System (ADS)

    Parker, L. K.; Morris, R. E.; Zapert, J.; Cook, F.; Koo, B.; Rasmussen, D.; Jung, J.; Grant, J.; Johnson, J.; Shah, T.; Pavlovic, T.

    2015-12-01

    The Colorado Air Resource Management Modeling Study (CARMMS) was funded by the Bureau of Land Management (BLM) to predict the impacts from future federal and non-federal energy development in Colorado and Northern New Mexico. The study used the Comprehensive Air Quality Model with extensions (CAMx) photochemical grid model (PGM) to quantify potential impacts from energy development from BLM field office planning areas. CAMx source apportionment technology was used to track the impacts from multiple (14) different emissions source regions (i.e. field office areas) within one simulation, as well as to assess the cumulative impact of emissions from all source regions combined. The energy development emissions estimates were for the year 2021 for three different development scenarios: (1) low; (2) high; (3) high with emissions mitigation. Impacts on air quality (AQ) including ozone, PM2.5, PM10, NO2, SO2, and air quality related values (AQRVs) such as atmospheric deposition, regional haze and changes in Acid Neutralizing Capacity (ANC) of lakes were quantified, and compared to establish threshold levels. In this presentation, we present a brief summary of the how the emission scenarios were developed, we compare the emission totals for each scenario, and then focus on the ozone impacts for each scenario to assess: (1). the difference in potential ozone impacts under the different development scenarios and (2). to establish the sensitivity of the ozone impacts to different emissions levels. Region-wide ozone impacts will be presented as well as impacts at specific locations with ozone monitors.

  4. Nutritional value of milk and meat products derived from cloning.

    PubMed

    Tomé, Daniel; Dubarry, Michel; Fromentin, Gilles

    2004-01-01

    The development and use of milk and meat products derived from cloning depends on their safety and on the nutritional advantages they can confer to the products as perceived by consumers. The development of such products thus implies (i) to demonstrate their safety and security, (ii) to show that their nutritional value is equivalent to the traditional products, and (iii) to identify the conditions under which cloning could allow additional nutritional and health benefit in comparison to traditional products for the consumers. Both milk and meat products are a source of high quality protein as determined from their protein content and essential amino acid profile. Milk is a source of calcium, phosphorus, zinc, magnesium and vitamin B2 and B12. Meat is a source of iron, zinc and vitamin B12. An important issue regarding the nutritional quality of meat and milk is the level and quality of fat which usually present a high content in saturated fat and some modification of the fat fraction could improve the nutritional quality of the products. The role of the dietary proteins as potential allergens has to be taken into account and an important aspect regarding this question is to evaluate whether the cloning does not produce the appearance of novel allergenic structures. The presence of bio-activities associated to specific components of milk (lactoferrin, immunoglobulins, growth factors, anti-microbial components) also represents a promising development. Preliminary results obtained in rats fed cow's milk or meat-based diets prepared from control animals or from animals derived from cloning did not show any difference between control and cloning-derived products.

  5. Database Quality and Access Issues Relevant to Research Using Anesthesia Information Management System Data.

    PubMed

    Epstein, Richard H; Dexter, Franklin

    2018-07-01

    For this special article, we reviewed the computer code, used to extract the data, and the text of all 47 studies published between January 2006 and August 2017 using anesthesia information management system (AIMS) data from Thomas Jefferson University Hospital (TJUH). Data from this institution were used in the largest number (P = .0007) of papers describing the use of AIMS published in this time frame. The AIMS was replaced in April 2017, making this finite sample finite. The objective of the current article was to identify factors that made TJUH successful in publishing anesthesia informatics studies. We examined the structured query language used for each study to examine the extent to which databases outside of the AIMS were used. We examined data quality from the perspectives of completeness, correctness, concordance, plausibility, and currency. Our results were that most could not have been completed without external database sources (36/47, 76.6%; P = .0003 compared with 50%). The operating room management system was linked to the AIMS and was used significantly more frequently (26/36, 72%) than other external sources. Access to these external data sources was provided, allowing exploration of data quality. The TJUH AIMS used high-resolution timestamps (to the nearest 3 milliseconds) and created audit tables to track changes to clinical documentation. Automatic data were recorded at 1-minute intervals and were not editable; data cleaning occurred during analysis. Few paired events with an expected order were out of sequence. Although most data elements were of high quality, there were notable exceptions, such as frequent missing values for estimated blood loss, height, and weight. Some values were duplicated with different units, and others were stored in varying locations. Our conclusions are that linking the TJUH AIMS to the operating room management system was a critical step in enabling publication of multiple studies using AIMS data. Access to this and other external databases by analysts with a high degree of anesthesia domain knowledge was necessary to be able to assess the quality of the AIMS data and ensure that the data pulled for studies were appropriate. For anesthesia departments seeking to increase their academic productivity using their AIMS as a data source, our experiences may provide helpful guidance.

  6. Spectral characteristics of quantum-cascade laser operating at 10.6 μm wavelength for a seed application in laser-produced-plasma extreme UV source.

    PubMed

    Nowak, Krzysztof M; Ohta, Takeshi; Suganuma, Takashi; Yokotsuka, Toshio; Fujimoto, Junichi; Mizoguchi, Hakaru; Endo, Akira

    2012-11-15

    In this Letter, we investigate, for the first time to our knowledge, the spectral properties of a quantum-cascade laser (QCL) from a point of view of a new application as a laser seeder for a nanosecond-pulse high-repetition frequency CO(2) laser operating at 10.6 μm wavelength. The motivation for this work is a renewed interest in such a pulse format and wavelength driven by a development of extreme UV (EUV) laser-produced-plasma (LPP) sources. These sources use pulsed multikilowatt CO(2) lasers to drive the EUV-emitting plasmas. Basic spectral performance characteristics of a custom-made QCL chip are measured, such as tuning range and chirp rate. The QCL is shown to have all essential qualities of a robust seed source for a high-repetition nanosecond-pulsed CO(2) laser required by EUV LPP sources.

  7. Characterization and source identification of pollutants in runoff from a mixed land use watershed using ordination analyses.

    PubMed

    Lee, Dong Hoon; Kim, Jin Hwi; Mendoza, Joseph A; Lee, Chang Hee; Kang, Joo-Hyon

    2016-05-01

    While identification of critical pollutant sources is the key initial step for cost-effective runoff management, it is challenging due to the highly uncertain nature of runoff pollution, especially during a storm event. To identify critical sources and their quantitative contributions to runoff pollution (especially focusing on phosphorous), two ordination methods were used in this study: principal component analysis (PCA) and positive matrix factorization (PMF). For the ordination analyses, we used runoff quality data for 14 storm events, including data for phosphorus, 11 heavy metal species, and eight ionic species measured at the outlets of subcatchments with different land use compositions in a mixed land use watershed. Five factors as sources of runoff pollutants were identified by PCA: agrochemicals, groundwater, native soils, domestic sewage, and urban sources (building materials and automotive activities). PMF identified similar factors to those identified by PCA, with more detailed source mechanisms for groundwater (i.e., nitrate leaching and cation exchange) and urban sources (vehicle components/motor oils/building materials and vehicle exhausts), confirming the sources identified by PCA. PMF was further used to quantify contributions of the identified sources to the water quality. Based on the results, agrochemicals and automotive activities were the two dominant and ubiquitous phosphorus sources (39-61 and 16-47 %, respectively) in the study area, regardless of land use types.

  8. A conceptual ground-water-quality monitoring network for San Fernando Valley, California

    USGS Publications Warehouse

    Setmire, J.G.

    1985-01-01

    A conceptual groundwater-quality monitoring network was developed for San Fernando Valley to provide the California State Water Resources Control Board with an integrated, basinwide control system to monitor the quality of groundwater. The geology, occurrence and movement of groundwater, land use, background water quality, and potential sources of pollution were described and then considered in designing the conceptual monitoring network. The network was designed to monitor major known and potential point and nonpoint sources of groundwater contamination over time. The network is composed of 291 sites where wells are needed to define the groundwater quality. The ideal network includes four specific-purpose networks to monitor (1) ambient water quality, (2) nonpoint sources of pollution, (3) point sources of pollution, and (4) line sources of pollution. (USGS)

  9. Sources of water pollution and evolution of water quality in the Wuwei basin of Shiyang river, Northwest China.

    PubMed

    Ma, Jinzhu; Ding, Zhenyu; Wei, Guoxiao; Zhao, Hua; Huang, Tianming

    2009-02-01

    Based on surveys and chemical analyses, we performed a case study of the surface water and groundwater quality in the Wuwei basin, in order to understand the sources of water pollution and the evolution of water quality in Shiyang river. Concentrations of major chemical elements in the surface water were related to the distance downstream from the source of the river, with surface water in the upstream reaches of good quality, but the river from Wuwei city to the Hongya reservoir was seriously polluted, with a synthetic pollution index of 25. Groundwater quality was generally good in the piedmont with dominant bicarbonate and calcium ions, but salinity was high and nitrate pollution occurs in the northern part of the basin. Mineralization of the groundwater has changed rapidly during the past 20 years. There are 23 wastewater outlets that discharge a total of 22.4 x 10(6)m(3)y(-1) into the river from Wuwei city, which, combined with a reduction of inflow water, were found to be the major causes of water pollution. Development of fisheries in the Hongya reservoir since 2000 has also contributed to the pollution. The consumption of water must be decreased until it reaches the sustainable level permitted by the available resources in the whole basin, and discharge of wastes must also be drastically reduced.

  10. Beam control of high-power broad-area photonic crystal lasers using ladderlike groove structure

    NASA Astrophysics Data System (ADS)

    Wang, Tao; Wang, Lijie; Shu, Shili; Tian, Sicong; Lu, Zefeng; Hou, Guanyu; Lu, Huanyu; Tong, Cunzhu; Wang, Lijun

    2017-06-01

    The high-power broad-area (BA) photonic bandgap crystal (PBC) diode laser is promising as a high-brightness laser source, however, it suffers from poor lateral beam quality owing to the intrinsic drawback of BA lasers. In this paper, a ladderlike groove structure (LLGS) was proposed to improve both the lateral beam quality and emission power of BA PBC lasers. An approximately 15.4% improvement in output power and 25.2% decrease in the lateral beam parameter product (BPP) were realized and the underlying mechanism was discussed. On the basis of the one-dimensional PBC epitaxial structure, a stable vertical far field was demonstrated.

  11. Calibration of Photon Sources for Brachytherapy

    NASA Astrophysics Data System (ADS)

    Rijnders, Alex

    Source calibration has to be considered an essential part of the quality assurance program in a brachytherapy department. Not only it will ensure that the source strength value used for dose calculation agrees within some predetermined limits to the value stated on the source certificate, but also it will ensure traceability to international standards. At present calibration is most often still given in terms of reference air kerma rate, although calibration in terms of absorbed dose to water would be closer to the users interest. It can be expected that in a near future several standard laboratories will be able to offer this latter service, and dosimetry protocols will have to be adapted in this way. In-air measurement using ionization chambers (e.g. a Baldwin—Farmer ionization chamber for 192Ir high dose rate HDR or pulsed dose rate PDR sources) is still considered the method of choice for high energy source calibration, but because of their ease of use and reliability well type chambers are becoming more popular and are nowadays often recommended as the standard equipment. For low energy sources well type chambers are in practice the only equipment available for calibration. Care should be taken that the chamber is calibrated at the standard laboratory for the same source type and model as used in the clinic, and using the same measurement conditions and setup. Several standard laboratories have difficulties to provide these calibration facilities, especially for the low energy seed sources (125I and 103Pd). Should a user not be able to obtain properly calibrated equipment to verify the brachytherapy sources used in his department, then at least for sources that are replaced on a regular basis, a consistency check program should be set up to ensure a minimal level of quality control before these sources are used for patient treatment.

  12. Enterococci in the environment

    USGS Publications Warehouse

    Byappanahalli, Muruleedhara N.; Nevers, Meredith B.; Korajkic, Asja; Staley, Zachery R.; Harwood, Valerie J.

    2012-01-01

    Enterococci are common, commensal members of gut communities in mammals and birds, yet they are also opportunistic pathogens that cause millions of human and animal infections annually. Because they are shed in human and animal feces, are readily culturable, and predict human health risks from exposure to polluted recreational waters, they are used as surrogates for waterborne pathogens and as fecal indicator bacteria (FIB) in research and in water quality testing throughout the world. Evidence from several decades of research demonstrates, however, that enterococci may be present in high densities in the absence of obvious fecal sources and that environmental reservoirs of these FIB are important sources and sinks, with the potential to impact water quality. This review focuses on the distribution and microbial ecology of enterococci in environmental (secondary) habitats, including the effect of environmental stressors; an outline of their known and apparent sources, sinks, and fluxes; and an overview of the use of enterococci as FIB. Finally, the significance of emerging methodologies, such as microbial source tracking (MST) and empirical predictive models, as tools in water quality monitoring is addressed. The mounting evidence for widespread extraenteric sources and reservoirs of enterococci demonstrates the versatility of the genus Enterococcus and argues for the necessity of a better understanding of their ecology in natural environments, as well as their roles as opportunistic pathogens and indicators of human pathogens.

  13. Enterococci in the Environment

    PubMed Central

    Byappanahalli, Muruleedhara N.; Nevers, Meredith B.; Korajkic, Asja; Staley, Zachery R.

    2012-01-01

    Summary: Enterococci are common, commensal members of gut communities in mammals and birds, yet they are also opportunistic pathogens that cause millions of human and animal infections annually. Because they are shed in human and animal feces, are readily culturable, and predict human health risks from exposure to polluted recreational waters, they are used as surrogates for waterborne pathogens and as fecal indicator bacteria (FIB) in research and in water quality testing throughout the world. Evidence from several decades of research demonstrates, however, that enterococci may be present in high densities in the absence of obvious fecal sources and that environmental reservoirs of these FIB are important sources and sinks, with the potential to impact water quality. This review focuses on the distribution and microbial ecology of enterococci in environmental (secondary) habitats, including the effect of environmental stressors; an outline of their known and apparent sources, sinks, and fluxes; and an overview of the use of enterococci as FIB. Finally, the significance of emerging methodologies, such as microbial source tracking (MST) and empirical predictive models, as tools in water quality monitoring is addressed. The mounting evidence for widespread extraenteric sources and reservoirs of enterococci demonstrates the versatility of the genus Enterococcus and argues for the necessity of a better understanding of their ecology in natural environments, as well as their roles as opportunistic pathogens and indicators of human pathogens. PMID:23204362

  14. Relations of surface-water quality to streamflow in the Hackensack, Passaic, Elizabeth, and Rahway River basins, New Jersey, water years 1976-93

    USGS Publications Warehouse

    Buxton, Debra E.; Hunchak-Kariouk, Kathryn; Hickman, R. Edward

    1998-01-01

    Relations of water quality to streamflow were determined for 18 water-quality constituents at 19 surface-water-quality stations within the drainage basins of the Hackensack, Passaic, Elizabeth, and Rahway Rivers in New Jersey for water years 1976-93. Surface-waterquality and streamflow data were evaluated for trends (through time) in constituent concentrations during high and low flows, and relations between constituent concentration and streamflow, and constituent load and streamflow, were determined. Median concentrations were calculated for the entire period of study (water years 1976-93) and for the last 5 years of the period of study (water years 1989-93) to determine whether any large variation in concentration exists between the two periods. Medians also were used to determine the seasonal Kendall’s tau statistic, which was then used to evaluate trends in concentrations during high and low flows.Trends in constituent concentrations during high and low flows were evaluated to determine whether the distribution of the observations changes over time for intermittent (nonpoint storm runoff) or constant (point sources and ground water) sources, respectively. Highand low-flow concentration trends were determined for some constituents at 11 of the 19 waterquality stations; 8 stations have insufficient data to determine trends. Seasonal effects on the relations of concentration to streamflow are evident for 16 of the 18 constituents. Negative slopes of relations of concentration to streamflow, which indicate a decrease in concentration at high flows, predominate over positive slopes because of dilution of instream concentrations from storm runoff.The slopes of the regression lines of load to streamflow were determined in order to show the relative contributions to the instream load from constant (point sources and ground water) and intermittent sources (storm runoff). Greater slope values suggest larger contributions from storm runoff to instream load, which most likely indicate an increased relative importance of nonpoint sources. Load-to-streamflow relations along a stream reach that tend to increase in a downstream direction indicate the increased relative importance of contributions from storm runoff. Likewise, load-to-streamflow relations along a stream reach that tend to decrease in a downstream direction indicate the increased relative importance of point sources and ground-water discharge. For most of the 18 constituents, load-to-streamflow relations at stations along a river reach remain constant or decrease in a downstream direction. The slopes increase in the downstream direction for some or all of the nutrient species at the Ramapo, lower Passaic, and Rahway Rivers; for dissolved solids, dissolved sodium, and dissolved chloride at the lower Passaic River; and for alkalinity and hardness at the Rahway River.

  15. Quantitative and qualitative analysis of naphthenic acids in natural waters surrounding the Canadian oil sands industry.

    PubMed

    Ross, Matthew S; Pereira, Alberto dos Santos; Fennell, Jon; Davies, Martin; Johnson, James; Sliva, Lucie; Martin, Jonathan W

    2012-12-04

    The Canadian oil sands industry stores toxic oil sands process-affected water (OSPW) in large tailings ponds adjacent to the Athabasca River or its tributaries, raising concerns over potential seepage. Naphthenic acids (NAs; C(n)H(2n-Z)O(2)) are toxic components of OSPW, but are also natural components of bitumen and regional groundwaters, and may enter surface waters through anthropogenic or natural sources. This study used a selective high-resolution mass spectrometry method to examine total NA concentrations and NA profiles in OSPW (n = 2), Athabasca River pore water (n = 6, representing groundwater contributions) and surface waters (n = 58) from the Lower Athabasca Region. NA concentrations in surface water (< 2-80.8 μg/L) were 100-fold lower than previously estimated. Principal components analysis (PCA) distinguished sample types based on NA profile, and correlations to water quality variables identified two sources of NAs: natural fatty acids, and bitumen-derived NAs. Analysis of NA data with water quality variables highlighted two tributaries to the Athabasca River-Beaver River and McLean Creek-as possibly receiving OSPW seepage. This study is the first comprehensive analysis of NA profiles in surface waters of the region, and demonstrates the need for highly selective analytical methods for source identification and in monitoring for potential effects of development on ambient water quality.

  16. Quality assessment of MEG-to-MRI coregistrations

    NASA Astrophysics Data System (ADS)

    Sonntag, Hermann; Haueisen, Jens; Maess, Burkhard

    2018-04-01

    For high precision in source reconstruction of magnetoencephalography (MEG) or electroencephalography data, high accuracy of the coregistration of sources and sensors is mandatory. Usually, the source space is derived from magnetic resonance imaging (MRI). In most cases, however, no quality assessment is reported for sensor-to-MRI coregistrations. If any, typically root mean squares (RMS) of point residuals are provided. It has been shown, however, that RMS of residuals do not correlate with coregistration errors. We suggest using target registration error (TRE) as criterion for the quality of sensor-to-MRI coregistrations. TRE measures the effect of uncertainty in coregistrations at all points of interest. In total, 5544 data sets with sensor-to-head and 128 head-to-MRI coregistrations, from a single MEG laboratory, were analyzed. An adaptive Metropolis algorithm was used to estimate the optimal coregistration and to sample the coregistration parameters (rotation and translation). We found an average TRE between 1.3 and 2.3 mm at the head surface. Further, we observed a mean absolute difference in coregistration parameters between the Metropolis and iterative closest point algorithm of (1.9 +/- 15){\\hspace{0pt}}\\circ and (1.1 +/- 9) m. A paired sample t-test indicated a significant improvement in goal function minimization by using the Metropolis algorithm. The sampled parameters allowed computation of TRE on the entire grid of the MRI volume. Hence, we recommend the Metropolis algorithm for head-to-MRI coregistrations.

  17. Performance of the K+ ion diode in the 2 MV injector for heavy ion fusion

    NASA Astrophysics Data System (ADS)

    Bieniosek, F. M.; Henestroza, E.; Kwan, J. W.

    2002-02-01

    Heavy ion beam inertial fusion driver concepts depend on the availability and performance of high-brightness high-current ion sources. Surface ionization sources have relatively low current density but high brightness because of the low temperature of the emitted ions. We have measured the beam profiles at the exit of the injector diode, and compared the measured profiles with EGUN and WARP-3D predictions. Spherical aberrations are significant in this large aspect ratio diode. We discuss the measured and calculated beam size and beam profiles, the effect of aberrations, quality of vacuum, and secondary electron distributions on the beam profile.

  18. Predicting fire effects on water quality: a perspective and future needs

    NASA Astrophysics Data System (ADS)

    Smith, Hugh; Sheridan, Gary; Nyman, Petter; Langhans, Christoph; Noske, Philip; Lane, Patrick

    2017-04-01

    Forest environments are a globally significant source of drinking water. Fire presents a credible threat to the supply of high quality water in many forested regions. The post-fire risk to water supplies depends on storm event characteristics, vegetation cover and fire-related changes in soil infiltration and erodibility modulated by landscape position. The resulting magnitude of runoff generation, erosion and constituent flux to streams and reservoirs determines the severity of water quality impacts in combination with the physical and chemical composition of the entrained material. Research to date suggests that most post-fire water quality impacts are due to large increases in the supply of particulates (fine-grained sediment and ash) and particle-associated chemical constituents. The largest water quality impacts result from high magnitude erosion events, including debris flow processes, which typically occur in response to short duration, high intensity storm events during the recovery period. Most research to date focuses on impacts on water quality after fire. However, information on potential water quality impacts is required prior to fire events for risk planning. Moreover, changes in climate and forest management (e.g. prescribed burning) that affect fire regimes may alter water quality risks. Therefore, prediction requires spatial-temporal representation of fire and rainfall regimes coupled with information on fire-related changes to soil hydrologic parameters. Recent work has applied such an approach by combining a fire spread model with historic fire weather data in a Monte Carlo simulation to quantify probabilities associated with fire and storm events generating debris flows and fine sediment influx to a reservoir located in Victoria, Australia. Prediction of fire effects on water quality would benefit from further research in several areas. First, more work on regional-scale stochastic modelling of intersecting fire and storm events with landscape zones of erosion vulnerability is required to support quantitative evaluation of water quality risk and the effect of future changes in climate and land management. Second, we underscore previous calls for characterisation of landscape-scale domains to support regionalisation of parameter sets derived from empirical studies. Recent examples include work identifying aridity as a control of hydro-geomorphic response to fire and the use of spectral-based indices to predict spatial heterogeneity in ash loadings. Third, information on post-fire erosion from colluvial or alluvial stores is needed to determine their significance as both sediment-contaminant sinks and sources. Such sediment stores may require explicit spatial representation in risk models for some environments and sediment tracing can be used to determine their relative importance as secondary sources. Fourth, increased dating of sediment archives could provide regional datasets of fire-related erosion event frequency. Presently, the lack of such data hinders evaluation of risk models linking fire and storm events to erosion and water quality impacts.

  19. Development of EPA aircraft piston engine emission standards. [for air quality

    NASA Technical Reports Server (NTRS)

    Houtman, W.

    1976-01-01

    Piston engine light aircraft are significant sources of carbon monoxide in the vicinity of high activity general aviation airports. Substantial reductions in carbon monoxide were achieved by fuel mixture leaning using improved fuel management systems. The air quality impact of the hydrocarbon and oxides of nitrogen emissions from piston engine light aircraft were insufficient to justify the design constraints being confronted in present control system developments.

  20. Social support moderates the effects of stress on sleep in adolescents.

    PubMed

    van Schalkwijk, Frank J; Blessinga, Agaath N; Willemen, Agnes M; Van Der Werf, Ysbrand D; Schuengel, Carlo

    2015-08-01

    Academic expectations and demands become primary sources of stress during adolescence, negatively affecting sleep. To cope with stress, adolescents may turn to social support figures. The present study tested the extent of main and moderating effects of various sources of social support on the association between stress and sleep. Adolescents (n = 202, meanage 14.6 years, standard deviation = 0.71) reported on academic stress, sleep, and support using questionnaires during a low- and high-stress period, defined by the absence or presence of examinations, respectively. Inquiries were made regarding social support from parents, friends, and class supervisor. During both stress periods, academic stress was associated negatively with sleep quality and positively with sleep reduction. Social support increased sleep quality and lowered sleep reduction. In addition, social support moderated the effects of academic stress on sleep, thus improving sleep quality and lowering sleep reduction. Moderating effects were stronger during a period of high stress. The present study showed that adolescents can benefit from stress moderation through social support by improvements of sleep quality and sleep reduction. Such moderating effects should be taken into account when studying stress and sleep. Implications and recommendations based on these findings are discussed. © 2015 European Sleep Research Society.

  1. Meat Quality Derived from High Inclusion of a Micro-Alga or Insect Meal as an Alternative Protein Source in Poultry Diets: A Pilot Study

    PubMed Central

    Neumann, Carmen; Velten, Susanne; Liebert, Frank

    2018-01-01

    The effects on meat quality resulting from alternative dietary protein sources (Spirulina and Hermetia meal) in poultry diets are studied to determine the overall suitability of these ingredients considering state-of-the-art packaging practices—highly oxygenated modified atmosphere packaging (HiOx MAP). We monitored standard slaughterhouse parameters, such as live weight, carcass weight, dressed yield, and pH at 20 min and 24 h post mortem. In addition, we studied the effects that 3 and 7-day storage in HiOx MAP has on the overall product physico-chemical and sensory properties. In addition to previously supported effects of HiOx MAP, we found that meat quality could be improved when Spirulina replaces 50% of the soy protein in broiler diets; however, this substitution results in a dark reddish-yellowish meat colour. On the other hand, the substitution with Hermetia larval meal results in a product that does not differ from the standard fed control group, with the exception that the breast filet has a more intense flavour that decreases over storage time. All-in-all Spirulina and Hermetia meal have the potential to replace soybean meal in broiler diets without deteriorating meat quality. PMID:29518048

  2. Depth-dependent groundwater quality sampling at City of Tallahassee test well 32, Leon County, Florida, 2013

    USGS Publications Warehouse

    McBride, W. Scott; Wacker, Michael A.

    2015-01-01

    A test well was drilled by the City of Tallahassee to assess the suitability of the site for the installation of a new well for public water supply. The test well is in Leon County in north-central Florida. The U.S. Geological Survey delineated high-permeability zones in the Upper Floridan aquifer, using borehole-geophysical data collected from the open interval of the test well. A composite water sample was collected from the open interval during high-flow conditions, and three discrete water samples were collected from specified depth intervals within the test well during low-flow conditions. Water-quality, source tracer, and age-dating results indicate that the open interval of the test well produces water of consistently high quality throughout its length. The cavernous nature of the open interval makes it likely that the highly permeable zones are interconnected in the aquifer by secondary porosity features.

  3. Nationwide assessment of nonpoint source threats to water quality

    Treesearch

    Thomas C. Brown; Pamela Froemke

    2012-01-01

    Water quality is a continuing national concern, in part because the containment of pollution from nonpoint (diffuse) sources remains a challenge. We examine the spatial distribution of nonpoint-source threats to water quality. On the basis of comprehensive data sets for a series of watershed stressors, the relative risk of water-quality impairment was estimated for the...

  4. Characterization of Long Working Distance Optical Coherence Tomography for Imaging of Pediatric Retinal Pathology.

    PubMed

    Qian, Ruobing; Carrasco-Zevallos, Oscar M; Mangalesh, Shwetha; Sarin, Neeru; Vajzovic, Lejla; Farsiu, Sina; Izatt, Joseph A; Toth, Cynthia A

    2017-10-01

    We determined the feasibility of fovea and optic nerve head imaging with a long working distance (LWD) swept source optical coherence tomography (OCT) prototype in adults, teenagers, and young children. A prototype swept source OCT system with a LWD (defined as distance from the last optical element of the imaging system to the eye) of 350 mm with custom fixation targets was developed to facilitate imaging of children. Imaging was performed in 49 participants from three age groups: 26 adults, 16 children 13 to 18 years old (teenagers), and seven children under 6 years old (young children) under an approved institutional review board protocol. The imaging goal was to acquire high quality scans of the fovea and optic nerve in each eye in the shortest time possible. OCT B-scans and volumes of the fovea and optic nerve head of each eligible eye were captured and graded based on four categories (lateral and axial centration, contrast, and resolution) and on ability to determine presence or absence of pathology. LWD-OCT imaging was successful in 88 of 94 eligible eyes, including seven of 10 eyes of young children. Of the successfully acquired OCT images, 83% of B-scan and volumetric images, including 86% from young children, were graded as high-quality scans. Pathology was observed in high-quality OCT images. The prototype LWD-OCT system achieved high quality retinal imaging of adults, teenagers, and some young children with and without pathology with reasonable alignment time. The LWD-OCT system can facilitate imaging in children.

  5. Characterization of Long Working Distance Optical Coherence Tomography for Imaging of Pediatric Retinal Pathology

    PubMed Central

    Qian, Ruobing; Carrasco-Zevallos, Oscar M.; Mangalesh, Shwetha; Sarin, Neeru; Vajzovic, Lejla; Farsiu, Sina; Izatt, Joseph A.; Toth, Cynthia A.

    2017-01-01

    Purpose We determined the feasibility of fovea and optic nerve head imaging with a long working distance (LWD) swept source optical coherence tomography (OCT) prototype in adults, teenagers, and young children. Methods A prototype swept source OCT system with a LWD (defined as distance from the last optical element of the imaging system to the eye) of 350 mm with custom fixation targets was developed to facilitate imaging of children. Imaging was performed in 49 participants from three age groups: 26 adults, 16 children 13 to 18 years old (teenagers), and seven children under 6 years old (young children) under an approved institutional review board protocol. The imaging goal was to acquire high quality scans of the fovea and optic nerve in each eye in the shortest time possible. OCT B-scans and volumes of the fovea and optic nerve head of each eligible eye were captured and graded based on four categories (lateral and axial centration, contrast, and resolution) and on ability to determine presence or absence of pathology. Results LWD-OCT imaging was successful in 88 of 94 eligible eyes, including seven of 10 eyes of young children. Of the successfully acquired OCT images, 83% of B-scan and volumetric images, including 86% from young children, were graded as high-quality scans. Pathology was observed in high-quality OCT images. Conclusions The prototype LWD-OCT system achieved high quality retinal imaging of adults, teenagers, and some young children with and without pathology with reasonable alignment time. Translational Relevance The LWD-OCT system can facilitate imaging in children. PMID:29057163

  6. Volume 3 - Area Sources and Area Source Method Abstracts

    EPA Pesticide Factsheets

    Nonpoint (area) source emission reference materials from the EIIP. Provides nonpoint source guidance on planning, emissions estimation, data collection, inventory documentation and reporting, and quality assurance/quality control.

  7. Soil contamination with cadmium, consequences and remediation using organic amendments.

    PubMed

    Khan, Muhammad Amjad; Khan, Sardar; Khan, Anwarzeb; Alam, Mehboob

    2017-12-01

    Cadmium (Cd) contamination of soil and food crops is a ubiquitous environmental problem that has resulted from uncontrolled industrialization, unsustainable urbanization and intensive agricultural practices. Being a toxic element, Cd poses high threats to soil quality, food safety, and human health. Land is the ultimate source of waste disposal and utilization therefore, Cd released from different sources (natural and anthropogenic), eventually reaches soil, and then subsequently bio-accumulates in food crops. The stabilization of Cd in contaminated soil using organic amendments is an environmentally friendly and cost effective technique used for remediation of moderate to high contaminated soil. Globally, substantial amounts of organic waste are generated every day that can be used as a source of nutrients, and also as conditioners to improve soil quality. This review paper focuses on the sources, generation, and use of different organic amendments to remediate Cd contaminated soil, discusses their effects on soil physical and chemical properties, Cd bioavailability, plant uptake, and human health risk. Moreover, it also provides an update of the most relevant findings about the application of organic amendments to remediate Cd contaminated soil and associated mechanisms. Finally, future research needs and directions for the remediation of Cd contaminated soil using organic amendments are discussed. Copyright © 2017 Elsevier B.V. All rights reserved.

  8. Relationship between Dietary Fat Intake, Its Major Food Sources and Assisted Reproduction Parameters

    PubMed Central

    Kazemi, Ashraf; Ramezanzadeh, Fatemeh; Nasr-Esfahani, Mohammad Hosein

    2014-01-01

    Background High dietary fat consumption may alter oocyte development and embryonic development. This prospective study was conducted to determine the relation between dietary fat consumption level, its food sources and the assisted reproduction parameters. Methods A prospective study was conducted on 240 infertile women. In assisted reproduction treatment cycle, fat consumption and major food sources over the previous three months were identified. The number of retrieved oocytes, metaphase ΙΙ stage oocytes numbers, fertilization rate, embryo quality and clinical pregnancy rate were also determined. The data were analyzed using multiple regression, binary logistic regression, chi-square and t-test. The p-value of less than 0.05 was considered significant. Results Total fat intake adjusted for age, body mass index, physical activity and etiology of infertility was positively associated with the number of retrieved oocytes and inversely associated with the high embryo quality rate. An inverse association was observed between sausage and turkey ham intake and the number of retrieved oocytes. Also, oil intake level had an inverse association with good cleavage rate. Conclusion The results revealed that higher levels of fat consumption tend to increase the number of retrieved oocytes and were adversely related to embryonic development. Among food sources of fat, vegetable oil, sausage and turkey ham intake may adversely affect assisted reproduction parameters. PMID:25473630

  9. Looking beyond the Internet: examining socioeconomic inequalities in cancer information seeking among cancer patients.

    PubMed

    Lee, Chul-Joo; Ramírez, A Susana; Lewis, Nehama; Gray, Stacy W; Hornik, Robert C

    2012-01-01

    The gap in cancer information seeking between high-socioeconomic-status (high-SES) cancer patients and low-SES cancer patients deserves serious attention, considering the importance of information and knowledge in cancer control. We thus explored the association of SES, as measured by education, with cancer patients' overall cancer information seeking, and with seeking from each source (i.e., the Internet, mass media, medical sources, and nonmedical interpersonal sources) and across two topic categories (i.e., treatment, quality of life). We then asked whether the effect of education on treatment information seeking is reduced among those who are particularly motivated to control treatment choices. We conducted a survey with breast, prostate, and colon cancer patients diagnosed in 2005 (n = 2,013), who were randomly drawn from the Pennsylvania Cancer Registry in the fall of 2006. We found that education was more strongly associated with Internet use than with the use of other sources regardless of topics. Also, when information was sought from mass media, education had a greater association with treatment information seeking than with quality-of-life information seeking. Preference for active participation in treatment decision making, however, did not moderate the effect of education on treatment information seeking. The implications of these findings for public health research and cancer patient education were discussed.

  10. Southern Mariana OBS Experiment and Preliminary Results of Passive-Source Investigations

    NASA Astrophysics Data System (ADS)

    Le, B. M.; Lin, J.; Yang, T.; Shiyan 3, S. P. O. R.

    2017-12-01

    The Southern Mariana OBS Experiment (SMOE) was one of the first seismic experiments targeting the deepest part of Earth's surface. During the Phase I experiment in December 2016, an array of OBS instruments were deployed across the Challenger Deep that recorded both active-source and passive-source data. During the Phase II experiment in December 2016-June 2017, passive-source data were recorded. We have retrieved earthquake signals and processed the waveforms from the recorded global, regional and local events, respectively, during the Phase I experiment. Most of the waveforms recorded by the OBS array have fairly good quality with discernible main phases. Rayleigh waves from many earthquakes were analyzed using the frequency-time analysis and their group velocities at different periods were obtained. The dispersion curves from different Rayleigh wave propagating paths would be valuable for inverting the structure of the subducting Pacific and overriding Philippine Sea plates. Furthermore, we applied the ambient noise cross-correlation method and retrieved high-quality coherence surface wave waveforms. With its relatively high frequencies, the surface waves can be used to study the crustal structure of the region. Together with the Phase II data, we expect that this seismic experiment will provide unprecedented constraints on the structure and geodynamic processes of the southern Mariana trench.

  11. Fecal-indicator bacteria in the Newfound Creek watershed, western North Carolina, during a high and low streamflow condition, 2003

    USGS Publications Warehouse

    Giddings, Elise M.; Oblinger, Carolyn J.

    2004-01-01

    Water quality in the Newfound Creek watershed has been shown to be affected by bacteria, sediment, and nutrients. In this study, Escherichia coli (E. coli) bacteria were sampled at five sites in Newfound Creek and five tributary sites during low flow on May 28, 2003, and high flow on November 19, 2003. In addition, a subset of five sites was sampled for fecal coliform bacteria, E. coli bacteria in streambed sediments (low flow only), and coliphage virus for serotyping. Coliphage virus serotyping has been used to identify human and animal sources of bacterial contamination. A streamflow gage was installed and operated to support ongoing water-quality studies in the watershed. Fecal coliform densities ranged from 92 to 27,000 colony-forming units per 100 milliliters of water for E. coli and 140 to an estimated 29,000 colony-forming units per 100 milliliters of water for fecal coliform during the two sampling visits. Ninety percent of the E. coli and fecal coliform samples exceeded corresponding U.S. Environmental Protection Agency or North Carolina water-quality criteria for recreational and ambient waters. During low flow, the middle part of the Newfound Creek watershed and the Dix Creek tributary had the highest densities of E. coli bacteria. During the high-flow sampling, all tributaries contained high densities of E. coli bacteria, although Dix Creek and Round Hill Branch were the largest contributors of these bacteria to Newfound Creek. Coliphage virus serotyping results were inconclusive because most samples did not contain the male-specific RNA coliphage needed for serotyping. Positive results indicated, however, that during low flow, non-human sources of bacteria were present in Sluder Branch, and during high flow, human sources of bacteria were present in Round Hill Branch. Sampling of bacteria in streambed sediments during low flow indicated that sediments do not appear to be a substantial source of bacteria relative to the water column, with the exception of an area near the confluence of Sluder Branch and Newfound Creek.

  12. High-performance perovskite CH3NH3PbI3 thin films for solar cells prepared by single-source physical vapour deposition

    PubMed Central

    Fan, Ping; Gu, Di; Liang, Guang-Xing; Luo, Jing-Ting; Chen, Ju-Long; Zheng, Zhuang-Hao; Zhang, Dong-Ping

    2016-01-01

    In this work, an alternative route to fabricating high-quality CH3NH3PbI3 thin films is proposed. Single-source physical vapour deposition (SSPVD) without a post-heat-treating process was used to prepare CH3NH3PbI3 thin films at room temperature. This new process enabled complete surface coverage and moisture stability in a non-vacuum solution. Moreover, the challenges of simultaneously controlling evaporation processes of the organic and inorganic sources via dual-source vapour evaporation and the heating process required to obtain high crystallization were avoided. Excellent composition with stoichiometry transferred from the powder material, a high level of tetragonal phase-purity, full surface coverage, well-defined grain structure, high crystallization and reproducibility were obtained. A PCE of approximately 10.90% was obtained with a device based on SSPVD CH3NH3PbI3. These initial results suggest that SSPVD is a promising method to significantly optimize perovskite CH3NH3PbI3 solar cell efficiency. PMID:27426686

  13. Construction and commissioning of the compact energy-recovery linac at KEK

    NASA Astrophysics Data System (ADS)

    Akemoto, Mitsuo; Arakawa, Dai; Asaoka, Seiji; Cenni, Enrico; Egi, Masato; Enami, Kazuhiro; Endo, Kuninori; Fukuda, Shigeki; Furuya, Takaaki; Haga, Kaiichi; Hajima, Ryoichi; Hara, Kazufumi; Harada, Kentaro; Honda, Tohru; Honda, Yosuke; Honma, Teruya; Hosoyama, Kenji; Kako, Eiji; Katagiri, Hiroaki; Kawata, Hiroshi; Kobayashi, Yukinori; Kojima, Yuuji; Kondou, Yoshinari; Tanaka, Olga; Kume, Tatsuya; Kuriki, Masao; Matsumura, Hiroshi; Matsushita, Hideki; Michizono, Shinichiro; Miura, Takako; Miyajima, Tsukasa; Nagahashi, Shinya; Nagai, Ryoji; Nakai, Hirotaka; Nakajima, Hiromitsu; Nakamura, Norio; Nakanishi, Kota; Nigorikawa, Kazuyuki; Nishimori, Nobuyuki; Nogami, Takashi; Noguchi, Shuichi; Obina, Takashi; Qiu, Feng; Sagehashi, Hidenori; Sakai, Hiroshi; Sakanaka, Shogo; Sasaki, Shinichi; Satoh, Kotaro; Sawamura, Masaru; Shimada, Miho; Shinoe, Kenji; Shishido, Toshio; Tadano, Mikito; Takahashi, Takeshi; Takai, Ryota; Takenaka, Tateru; Tanimoto, Yasunori; Uchiyama, Takashi; Ueda, Akira; Umemori, Kensei; Watanabe, Ken; Yamamoto, Masahiro

    2018-01-01

    Energy-recovery linacs (ERLs) are promising for advanced synchrotron light sources, high-power free electron lasers (FELs), high-brightness gamma-ray sources, and electron-ion colliders. To demonstrate the critical technology of ERL-based light sources, we have designed and constructed a test accelerator, the compact ERL (cERL). Using advanced technology that includes a photocathode direct current (DC) electron gun and two types of 1.3-GHz-frequency superconducting cavities, the cERL was designed to be capable of recirculating low emittance (≤1 mm ṡ mrad) and high average-current (≥10 mA) electron beams while recovering the beam energy. During initial commissioning, the cERL demonstrated successful recirculation of high-quality beams with normalized transverse emittance of ∼0.14 mm ṡ mrad and momentum spread of ∼1.2 × 10-4 (rms) at a beam energy of 20 MeV and bunch charge below 100 fC. Energy recovery in the superconducting main linac was also demonstrated for high-average-current continuous-wave beams. These results constitute an important milestone toward realizing ERL-based light sources.

  14. Contributions of regional and intercontinental transport to surface ozone in the Tokyo area

    NASA Astrophysics Data System (ADS)

    Yoshitomi, M.; Wild, O.; Akimoto, H.

    2011-08-01

    Japan lies downwind of the Asian continent and for much of the year air quality is directly influenced by emissions of ozone precursors over these heavily-populated and rapidly-industrializing regions. This study examines the extent to which oxidant transport from regional and distant anthropogenic sources influences air quality in Japan in springtime, when these contributions are largest. We find that European and North American contributions to surface ozone over Japan in spring are persistent, averaging 3.5±1.1 ppb and 2.8±0.5 ppb respectively, and are greatest in cold continental outflow conditions following the passage of cold fronts. Contributions from China are larger, 4.0±2.8 ppb, and more variable, as expected for a closer source region, and are generally highest near cold fronts preceding the influence of more distant sources. The stratosphere provides a varying but ever-present background of ozone of about 11.2±2.5 ppb during spring. Local sources over Japan and Korea have a relatively small impact on mean ozone, 2.4±7.6 ppb, but this masks a strong diurnal signal, and local sources clearly dominate during episodes of high daytime ozone. By examining the meteorological mechanisms that favour transport from different source regions, we demonstrate that while maximum foreign influence generally does not occur at the same time as the greatest buildup of oxidants from local sources, it retains a significant influence under these conditions. It is thus clear that while meteorological boundaries provide some protection from foreign influence during oxidant outbreaks in Tokyo, these distant sources still make a substantial contribution to exceedance of the Japanese ozone air quality standard in springtime.

  15. Contributions of regional and intercontinental transport to surface ozone in Tokyo

    NASA Astrophysics Data System (ADS)

    Yoshitomi, M.; Wild, O.; Akimoto, H.

    2011-04-01

    Japan lies downwind of the Asian continent and for much of the year air quality is directly influenced by emissions of ozone precursors over these heavily-populated and rapidly-industrializing regions. This study examines the extent to which oxidant transport from regional and distant anthropogenic sources influences air quality in Japan in springtime, when these contributions are largest. We find that European and North American contributions to surface ozone over Japan in spring are persistent, averaging 3.5±1.1 ppb and 2.8±0.5 ppb respectively, and are greatest in cold continental outflow conditions following the passage of cold fronts. Contributions from China are larger, 4.0±2.8 ppb, and more variable, as expected for a closer source region, and are generally highest near cold fronts preceding the influence of more distant sources. The stratosphere provides a varying but ever-present background of ozone of about 11.2±2.5 ppb during spring. Local sources over Japan and Korea have a relatively small impact on mean ozone, 2.4±7.6 ppb, but this masks a strong diurnal signal, and local sources clearly dominate during episodes of high daytime ozone. By examining the meteorological mechanisms that favour transport from different source regions, we demonstrate that while maximum foreign influence generally does not occur at the same time as the greatest buildup of oxidants from local sources, it retains a significant influence under these conditions. It is thus clear that while meteorological boundaries provide some protection from foreign influence during oxidant outbreaks in Tokyo, these distant sources still make a substantial contribution to exceedance of the Japanese ozone air quality standard in springtime.

  16. Assessment of the neutron cross section database for mercury for the ORNL spallation source

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Leal, L.C.; Spencer, R.R.; Ingersoll, D.T.

    1996-06-01

    Neutron source generation based on a high energy particle accelerator has been considered as an alternative to the canceled Advanced Neutron Source project at Oak Ridge National Laboratory. The proposed technique consists of a spallation neutron source in which neutrons are produced via the interaction of high-energy charged particles in a heavy metal target. Preliminary studies indicate that liquid mercury bombarded with GeV protons provides an excellent neutron source. Accordingly, a survey has been made of the available neutron cross-section data. Since it is expected that spectral modifiers, specifically moderators, will also be incorporated into the source design, the surveymore » included thermal energy, resonance region, and high energy data. It was found that data of individual isotopes were almost non-existent and that the only evaluation found for the natural element had regions of missing data or discrepant data. Therefore, it appears that to achieve the desired degree of accuracy in the spallation source design it is necessary to re-evaluate the mercury database including making new measurements. During the presentation the currently available data will be presented and experiments proposed which can lead to design quality cross sections.« less

  17. JPRS Report, Science & Technology, China

    DTIC Science & Technology

    1991-05-31

    below) are as is a functional cooling source for high -Tc supercon- follows: in the fast operating mode, system frequency ducting devices. Applications...with EIMAC quality standards, and agreed that chamber and pulse magnetic field. Employing a high - the products could bear the EIMAC trademark for...calculations show that operate in a high -order mode, and provide a very high the grating, as a frequency -scan antenna, can produce output power and

  18. Use of quality information in decision-making about health and social care services--a systematic review.

    PubMed

    Turnpenny, Agnes; Beadle-Brown, Julie

    2015-07-01

    User choice and personalisation have been at the centre of health and social care policies in many countries. Exercising choice can be especially challenging for people with long-term conditions (LTC) or disabilities. Information about the quality, cost and availability of services is central to user choice. This study used systematic review methods to synthesise evidence in three main areas: (i) how people with LTC or disabilities and their family carers find and access information about the quality of services; (ii) how quality information is used in decision-making; and (iii) what type of quality information is most useful. Quality information was defined broadly and could include formal quality reports (e.g. inspection reports, report cards, etc.), information about the characteristics of a service or provider (e.g. number and qualifications of staff, facilities, etc.) and informal reports about quality (e.g. personal experience, etc.). Literature searches were carried out using electronic databases in January 2012. Thirteen papers reporting findings from empirical studies published between 2001 and 2012 were included in the review. The majority of papers (n = 9) had a qualitative design. The analysis highlighted the use of multiple sources of information in decision-making about services and in particular the importance of informal sources and extended social networks in accessing information. There is limited awareness and use of 'official' and online information sources. Service users or family carers place greater emphasis on general information and structural indicators. Clinical or quality-of-life outcomes are often difficult to interpret and apply. Trust emerged a key issue in relation to quality information. Experiential and subjective information is highly valued and trusted. Various barriers to the effective use of quality information in making choices about services are identified. Implications for policy and future research are discussed. © 2014 John Wiley & Sons Ltd.

  19. Development of plasma assisted thermal vapor deposition technique for high-quality thin film.

    PubMed

    Lee, Kang-Il; Choi, Yong Sup; Park, Hyun Jae

    2016-12-01

    The novel technique of Plasma-Assisted Vapor Deposition (PAVD) is developed as a new deposition method for thin metal films. The PAVD technique yields a high-quality thin film without any heating of the substrate because evaporated particles acquire energy from plasma that is confined to the inside of the evaporation source. Experiments of silver thin film deposition have been carried out in conditions of pressure lower than 10 -3 Pa. Pure silver plasma generation is verified by the measurement of the Ag-I peak using optical emission spectroscopy. A four point probe and a UV-VIS spectrophotometer are used to measure the electrical and optical properties of the silver film that is deposited by PAVD. For an ultra-thin silver film with a thickness of 6.5 nm, we obtain the result of high-performance silver film properties, including a sheet resistance <20 Ω sq -1 and a visible-range transmittance >75%. The PAVD-film properties show a low sheet resistance of 30% and the same transmittance with conventional thermal evaporation film. In the PAVD source, highly energetic particles and UV from plasma do not reach the substrate because the plasma is completely shielded by the optimized nozzle of the crucible. This new PAVD technique could be a realistic solution to improve the qualities of transparent electrodes for organic light emission device fabrication without causing damage to the organic layers.

  20. Organic Matter in Rivers: The Crossroads between Climate and Water Quality

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davisson, M L

    2001-04-27

    All surface waters in the world contain dissolved organic matter and its concentration depends on climate and vegetation. Dissolved organic carbon (DOC) is ten times higher in wetlands and swamps than in surface water of arctic, alpine, or arid climate. Climates of high ecosystem productivity (i.e., tropics) typically have soils with low organic carbon storage, but drain high dissolved organic loads to rivers. Regions with lower productivity (e.g. grasslands) typically have high soil carbon storage while adjacent rivers have high DOC contents. Most DOC in a free-flowing river is derived from leaching vegetation and soil organic matter, whereas in dammedmore » rivers algae may comprise a significant portion. Water chemistry and oxygen-18 abundance of river water, along with radiocarbon and carbon-13 isotope abundance measurements of DOC were used to distinguish water and water quality sources in the Missouri River watershed. Drinking water for the City of St. Louis incorporates these different sources, and its water quality depends mostly on whether runoff is derived from the upper or the lower watershed, with the lower watershed contributing water with the highest DOC. During drinking water chlorination, DOC forms carcinogenic by-products in proportion to the amount of DOC present. This has recently led the USEPA to propose federal regulation standards. Restoration of natural riparian habitat such as wetlands will likely increase DOC concentrations in river water.« less

  1. Development of plasma assisted thermal vapor deposition technique for high-quality thin film

    NASA Astrophysics Data System (ADS)

    Lee, Kang-Il; Choi, Yong Sup; Park, Hyun Jae

    2016-12-01

    The novel technique of Plasma-Assisted Vapor Deposition (PAVD) is developed as a new deposition method for thin metal films. The PAVD technique yields a high-quality thin film without any heating of the substrate because evaporated particles acquire energy from plasma that is confined to the inside of the evaporation source. Experiments of silver thin film deposition have been carried out in conditions of pressure lower than 10-3 Pa. Pure silver plasma generation is verified by the measurement of the Ag-I peak using optical emission spectroscopy. A four point probe and a UV-VIS spectrophotometer are used to measure the electrical and optical properties of the silver film that is deposited by PAVD. For an ultra-thin silver film with a thickness of 6.5 nm, we obtain the result of high-performance silver film properties, including a sheet resistance <20 Ω sq-1 and a visible-range transmittance >75%. The PAVD-film properties show a low sheet resistance of 30% and the same transmittance with conventional thermal evaporation film. In the PAVD source, highly energetic particles and UV from plasma do not reach the substrate because the plasma is completely shielded by the optimized nozzle of the crucible. This new PAVD technique could be a realistic solution to improve the qualities of transparent electrodes for organic light emission device fabrication without causing damage to the organic layers.

  2. Improving bladder cancer patient care: a pharmacoeconomic perspective.

    PubMed

    Gore, John L; Gilbert, Scott M

    2013-06-01

    Bladder cancer is the most expensive cancer per capita to treat in the US healthcare system. Substantial costs associated with the diagnosis, management and surveillance of bladder cancer account for the bulk of the expense; yet, for that cost, patients may not receive high-quality care. Herein the authors review the sources of expenditure associated with bladder cancer care, review population-level analyses of the quality of bladder cancer care in the USA, and discuss opportunities for quality improvement that may yield greater value for men and women newly diagnosed with bladder cancer.

  3. Source contributions to United States ozone and particulate matter over five decades from 1970 to 2020

    NASA Astrophysics Data System (ADS)

    Nopmongcol, Uarporn; Alvarez, Yesica; Jung, Jaegun; Grant, John; Kumar, Naresh; Yarwood, Greg

    2017-10-01

    Evaluating long-term air quality trends can demonstrate effectiveness of control strategies and guide future air quality management planning. Observations have shown that ozone (O3) and fine particulate matter (PM2.5) in the US have declined since as early as 1980 in some areas. But observation trends alone cannot separate effects of changes in local and global emissions to US air quality which are important to air quality planners. This study uses a regional model (CAMx) nested within a global model (GEOS-Chem) to characterize regional changes in O3 and PM2.5 due to the intercontinental transport and local/regional emissions representing six modeling years within five decades (1970-2020). We use the CAMx Source Apportionment Technology (OSAT/PSAT) to estimate contributions from 6 source sectors in 7 source regions plus 6 other groups for a total of 48 tagged contributions. On-road mobile sources consistently make the largest U.S. anthropogenic emissions contribution to O3 in all cities examined even though they decline substantially from 1970 to 2005 and also from 2005 to 2020. Off-road mobile source contributions increase from 1970 to 2005 and then decrease after 2005 in all of the cities. The boundary conditions, mostly from intercontinental transport, contribute more than 20 ppb to high maximum daily 8-h average (MDA8) O3 for all six years. We found that lowering NOx emissions raises O3 formation efficiency (OFE) across all emission categories which will limit potential O3 benefits of local NOx strategies in the near future. PM2.5 benefited from adoption of control devices between 1970 and 1980 and has continued to decline through 2005 and expected to decline further by 2020. Area sources such as residential, commercial and fugitive dust emissions stand out as making large contributions to PM2.5 that are not declining. Inter-regional transport is less important in 2020 than 1990 for both pollutants.

  4. Refractive Optics for Hard X-ray Transmission Microscopy

    NASA Astrophysics Data System (ADS)

    Simon, M.; Ahrens, G.; Last, A.; Mohr, J.; Nazmov, V.; Reznikova, E.; Voigt, A.

    2011-09-01

    For hard x-ray transmission microscopy at photon energies higher than 15 keV we design refractive condenser and imaging elements to be used with synchrotron light sources as well as with x-ray tube sources. The condenser lenses are optimized for low x-ray attenuation—resulting in apertures greater than 1 mm—and homogeneous intensity distribution on the detector plane, whereas the imaging enables high-resolution (<100 nm) full-field imaging. To obtain high image quality at reasonable exposure times, custom-tailored matched pairs of condenser and imaging lenses are being developed. The imaging lenses (compound refractive lenses, CRLs) are made of SU-8 negative resist by deep x-ray lithography. SU-8 shows high radiation stability. The fabrication technique enables high-quality lens structures regarding surface roughness and arrangement precision with arbitrary 2D geometry. To provide point foci, crossed pairs of lenses are used. Condenser lenses have been made utilizing deep x-ray lithographic patterning of thick SU-8 layers, too, whereas in this case, the aperture is limited due to process restrictions. Thus, in terms of large apertures, condenser lenses made of structured and rolled polyimide film are more attractive. Both condenser types, x-ray mosaic lenses and rolled x-ray prism lenses (RXPLs), are considered to be implemented into a microscope setup. The x-ray optical elements mentioned above are characterized with synchrotron radiation and x-ray laboratory sources, respectively.

  5. Enhancing the quality of case studies in health services research.

    PubMed Central

    Yin, R K

    1999-01-01

    OBJECTIVE: To provide guidance on improving the quality of case studies in health services research. DATA SOURCES: Secondary data, drawing from previous case study research. RESEARCH DESIGN: Guidance is provided to two audiences: potential case study investigators (eight items) and reviewers of case study proposals (four additional items). PRINCIPAL FINDINGS: The guidance demonstrates that many operational steps can be undertaken to improve the quality of case studies. These steps have been a hallmark of high-quality case studies in related fields but have not necessarily been practiced in health services research. CONCLUSIONS: Given higher-quality case studies, the case study method can become a valuable tool for health services research. Images Figure 3 PMID:10591280

  6. Metabolic routing of dietary nutrients in birds: effects of diet quality and macronutrient composition revealed using stable isotopes.

    PubMed

    Podlesak, David W; McWilliams, Scott R

    2006-01-01

    During fall migration many songbirds switch from consuming primarily insects to consuming mostly fruit. Fruits with more carbohydrates and less protein may be sufficient to rebuild expended fat stores, but such fruits may be inadequate to replace catabolized protein. We manipulated the concentrations and isotopic signatures of macronutrients in diets fed to birds to study the effects of diet quality on metabolic routing of dietary nutrients. We estimated that approximately 45% and 75%, respectively, of the carbon in proteinaceous tissue of birds switched to high- or low-protein diets came from nonprotein dietary sources. In contrast, we estimated that approximately 100% and 20%-80%, respectively, of the nitrogen in proteinaceous tissues of birds switched to high- or low-protein diets was attributable to dietary protein. Thus, the routing and assimilation of dietary carbon and nitrogen differed depending on diet composition. As a result, delta (15)N of tissues collected from wild animals that consume high-quality diets may reliably indicate the dietary protein source, whereas delta (13)C of these same tissues is likely the product of metabolic routing of carbon from several macronutrients. These results have implications for how isotopic discrimination is best estimated and how we can study macronutrient routing in wild animals.

  7. Microbial Risk Assessment of Air Conditioning Condensate Reuse

    EPA Science Inventory

    Air conditioning condensate can provide a substantial water source for building-scale collection and non-potable use. Although produced water is anticipated to be of generally high quality, the potential for microbial contamination by biofilm-associated opportunistic pathogens t...

  8. Opportunities for Neutrino Physics at the Spallation Neutron Source: A White Paper

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bolozdynya, A.; Cavanna, F.; Efremenko, Y.

    2012-11-01

    The Spallation Neutron Source (SNS) at Oak Ridge National Laboratory, Tennessee, provides an intense flux of neutrinos in the few tens-of-MeV range, with a sharply-pulsed timing structure that is beneficial for background rejection. In this document, the product of a workshop at the SNS in May 2012, we describe this free, high-quality stopped-pion neutrino source and outline various physics that could be done using it. We describe without prioritization some specific experimental configurations that could address these physics topics.

  9. Implications of salinity pollution hotspots on agricultural production

    NASA Astrophysics Data System (ADS)

    Floerke, Martina; Fink, Julia; Malsy, Marcus; Voelker, Jeanette; Alcamo, Joseph

    2016-04-01

    Salinity pollution can have many negative impacts on water resources used for drinking, irrigation, and industrial purposes. Elevated concentrations of salinity in irrigation water can lead to decreased crop production or crop death and, thus, causing an economic problem. Overall, salinity pollution is a global problem but tends to be more severe in arid and semi-arid regions where the dilution capacity of rivers and lakes is lower and the use of irrigation higher. Particularly in these regions agricultural production is exposed to high salinity of irrigation water as insufficient water quality further reduces the available freshwater resources. According to the FAO, irrigated agriculture contributes about 40 percent of the total food production globally, and therefore, high salinity pollution poses a major concern for food production and food security. We use the WaterGAP3 modeling framework to simulate hydrological, water use, and water quality conditions on a global scale for the time period 1990 to 2010. The modeling framework is applied to simulate total dissolved solids (TDS) loadings and in-stream concentrations from different point and diffuse sources to get an insight on potential environmental impacts as well as risks to agricultural food production. The model was tested and calibrated against observed data from GEMStat and literature sources. Although global in scope, the focus of this study is on developing countries, i.e., in Africa, Asia, and Latin America, as these are most threatened by salinity pollution. Furthermore, insufficient water quality for irrigation and therefore restrictions in irrigation water use are examined, indicating limitations to crop production. Our results show that elevated salinity concentrations in surface waters mainly occur in peak irrigation regions as irrigated agriculture is not only the most relevant water use sector contributing to water abstractions, but also the dominant source of salinity pollution. Additionally, large metropolitan regions are initially loading hotspots and pollution, too, and prevention becomes important as point sources are dependent on sewer connection rates and treatment levels. In conclusion, this study provides a detailed picture of the spatial and temporal distribution of salinity pollution and identifies hotspot areas as well as the dominant sources. Furthermore, impacts of water quality degradation on agricultural production and food security are quantified, which aim for a better understanding of the risks for food security caused by water quality impairment.

  10. Impact of organic matter source and quality on living benthic foraminiferal distribution on a river-dominated continental margin: A study of the Portuguese margin

    NASA Astrophysics Data System (ADS)

    Dessandier, Pierre-Antoine; Bonnin, Jérôme; Kim, Jung-Hyun; Bichon, Sabrina; Deflandre, Bruno; Grémare, Antoine; Sinninghe Damsté, Jaap S.

    2016-06-01

    Living (rose Bengal stained) benthic foraminifera were investigated on surface sediments from 23 stations from the river-dominated northwestern Portuguese margin. Samples were collected in March 2011, following the period of the maximum rainfall over the Iberian Peninsula, between 20 and 2000 m water depth along five cross-margin transects. Four of them are located off the Douro, Mondego, Tagus, and Sado Rivers and one off the Estremadura coast. The major objectives of this study are (1) to assess the impact of organic matter of various origin and quality on the benthic foraminifera and (2) to investigate the spatial differences of faunal distribution from coastal waters to the deep sea under river influences. To do this, sedimentological and biogeochemical characteristics of the sediments were identified by measuring grain size, oxygen penetration depth, total organic carbon (TOC) content, stable carbon isotopic composition of TOC (δ13CTOC) and concentration of pigments and amino acids. Based on the principal component and cluster analyses of the environmental data, three major geographical groups are identified: (1) deep stations, (2) coastal and middle slope stations, and (3) shelf stations under river influence. At the deepest stations, species are associated with high organic matter (OM) quantity but low OM quality, where Uvigerina mediterranea, Hoeglundina elegans, and agglutinated species such as Reophax scorpiurus or Bigenerina nodosaria are dominant. All stations off the Sado River, which is the most affected area by the anthropogenic influence, are also characterized by high quantity but low quality of OM with the minimum faunal density and diversity within the study area. Middle slope stations are associated with low OM content and coarse sediments (Q50) with the predominance of N. scaphum. Shallow shelf stations close to the Douro and Tagus River mouths show a dominance of taxa (e.g., Ammonia beccarii, Bulimina aculeata, Eggerelloides scaber, Nonion scaphum, Cancris auriculus, and Quinqueloculina seminula) adapted to environments characterized by high OM quality (high fresh chlorophyll (Chl a/Phaeo)) and available amino acids (enzymatically hydrolyzable amino acid (EHAA)/total enzymatically hydrolyzable amino acid (THAA)). The Biotic and Environmental linking analysis suggests that the benthic foraminiferal distribution is mostly controlled by three environmental parameters, i.e., TOC (quantity), EHAA/THAA (quality), and δ13CTOC (source). Hence, this study clearly highlights that the quantitative and qualitative inputs of OM and its source are the most important factors controlling the living benthic foraminiferal distribution with clear influences between the different rivers. This study also suggests a good tolerance of several species for river discharges where the OM quality is high.

  11. Light use efficiency for vegetables production in protected and indoor environments

    NASA Astrophysics Data System (ADS)

    Cocetta, Giacomo; Casciani, Daria; Bulgari, Roberta; Musante, Fulvio; Kołton, Anna; Rossi, Maurizio; Ferrante, Antonio

    2017-01-01

    In recent years, there is a growing interest for vegetables production in indoor or disadvantaged climatic zones by using greenhouses. The main problem of crop growing indoor or in environment with limited light availability is the correct choice of light source and the quality of lighting spectrum. In greenhouse and indoor cultivations, plant density is higher than in the open field and plants have to compete for light and nutrients. Nowadays, advanced systems for indoor horticulture use light emitting diodes (LED) for improving crop growth, enhancing the plant productivity and favouring the best nutritional quality formation. In closed environments, as indoor growing modules, the lighting system represents the only source of light and its features are fundamental for obtaining the best lighting performances for plant and the most efficient solution. LED lighting engines are more efficient compared to the lighting sources used traditionally in horticulture and allow light spectrum and intensity modulations to enhance the light use efficiency for plants. The lighting distribution and the digital controls are fundamental for tailoring the spectral distribution on each plant in specific moments of its growth and play an important role for optimizing growth and produce high-quality vegetables. LED lights can increase plant growth and yield, but also nutraceutical quality, since some light intensities increase pigments biosynthesis and enhance the antioxidants content of leaves or fruits: in this regards the selection of LED primary light sources in relation to the peaks of the absorbance curve of the plants is important.

  12. OPEN-SOURCE SOFTWARE IN DENTISTRY: A SYSTEMATIC REVIEW.

    PubMed

    Chruściel-Nogalska, Małgorzata; Smektała, Tomasz; Tutak, Marcin; Sporniak-Tutak, Katarzyna; Olszewski, Raphael

    2017-01-01

    Technological development and the need for electronic health records management resulted in the need for a computer with dedicated, commercial software in daily dental practice. The alternative for commercial software may be open-source solutions. Therefore, this study reviewed the current literature on the availability and use of open-source software (OSS) in dentistry. A comprehensive database search was performed on February 1, 2017. Only articles published in peer-reviewed journals with a focus on the use or description of OSS were retrieved. The level of evidence, according to Oxford EBM Centre Levels of Evidence Scale was classified for all studies. Experimental studies underwent additional quality reporting assessment. The screening and evaluation process resulted in twenty-one studies from 1,940 articles found, with 10 of them being experimental studies. None of the articles provided level 1 evidence, and only one study was considered high quality following quality assessment. Twenty-six different OSS programs were described in the included studies of which ten were used for image visualization, five were used for healthcare records management, four were used for educations processes, one was used for remote consultation and simulation, and six were used for general purposes. Our analysis revealed that the dental literature on OSS consists of scarce, incomplete, and methodologically low quality information.

  13. Quality of drinking-water at source and point-of-consumption--drinking cup as a high potential recontamination risk: a field study in Bolivia.

    PubMed

    Rufener, Simonne; Mäusezahl, Daniel; Mosler, Hans-Joachim; Weingartner, Rolf

    2010-02-01

    In-house contamination of drinking-water is a persistent problem in developing countries. This study aimed at identifying critical points of contamination and determining the extent of recontamination after water treatment. In total, 81 households were visited, and 347 water samples from their current sources of water, transport vessels, treated water, and drinking vessels were analyzed. The quality of water was assessed using Escherichia coli as an indicator for faecal contamination. The concentration of E. coli increased significantly from the water source [median=0 colony-forming unit (CFU)/100 mL, interquartile range (IQR: 0-13)] to the drinking cup (median=8 CFU/100 mL; IQR: 0-550; n=81, z=-3.7, p<0.001). About two-thirds (34/52) of drinking vessels were contaminated with E. coli. Although boiling and solar disinfection of water (SODIS) improved the quality of drinking-water (median=0 CFU/100 mL; IQR: 0-0.05), recontamination at the point-of-consumption significantly reduced the quality of water in the cups (median=8, IQR: 0-500; n=45, z=-2.4, p=0.015). Home-based interventions in disinfection of water may not guarantee health benefits without complementary hygiene education due to the risk of posttreatment contamination.

  14. Informed Source Separation: A Bayesian Tutorial

    NASA Technical Reports Server (NTRS)

    Knuth, Kevin H.

    2005-01-01

    Source separation problems are ubiquitous in the physical sciences; any situation where signals are superimposed calls for source separation to estimate the original signals. In h s tutorial I will discuss the Bayesian approach to the source separation problem. This approach has a specific advantage in that it requires the designer to explicitly describe the signal model in addition to any other information or assumptions that go into the problem description. This leads naturally to the idea of informed source separation, where the algorithm design incorporates relevant information about the specific problem. This approach promises to enable researchers to design their own high-quality algorithms that are specifically tailored to the problem at hand.

  15. The quality of drinking water stored in canteens of field soldiers as a potential source of enteric diseases.

    PubMed

    Gavrieli, Benjamin; Potasman, Israel; Armon, Robert H

    2010-06-01

    Israel Defense Forces (IDF) guidelines for drinking water require the use of water only from sources that have been inspected and authorized by a medical expert. This study aimed to compare canteen water quality of two military units (infantry and armoured corps), to search for sources of possible microbial contamination and to look for any impact on gastrointestinal symptoms. Statistical analysis revealed that canteens of armoured corp soldiers were significantly more contaminated compared to those of infantry soldiers. Outdoor taps and water in trailers were found to harbour significantly higher numbers of microbial indicators compared to showers/lavatory sources; however, the numbers were much lower compared to canteens. Canteen water retention for more than one day revealed significantly increased numbers of examined microbial parameters, possibly due to secondary contamination or regrowth. Gastrointestinal symptoms were not significantly different between the two units despite the significant canteen water quality difference. An odds ratio evaluation was conducted on 45 exposure-illness combinations based on gastrointestinal symptoms, exposure and soldiers affiliation. Out of these 45 combinations only 14 resulted in odds ratio > 1, where 3 had high values (7.44, 7.46 and 11.2) suggesting a possible connection between diarrhoea and/or vomiting versus coliphages and faecal coliforms.

  16. Interactive Augmentation of Voice Quality and Reduction of Breath Airflow in the Soprano Voice.

    PubMed

    Rothenberg, Martin; Schutte, Harm K

    2016-11-01

    In 1985, at a conference sponsored by the National Institutes of Health, Martin Rothenberg first described a form of nonlinear source-tract acoustic interaction mechanism by which some sopranos, singing in their high range, can use to reduce the total airflow, to allow holding the note longer, and simultaneously enrich the quality of the voice, without straining the voice. (M. Rothenberg, "Source-Tract Acoustic Interaction in the Soprano Voice and Implications for Vocal Efficiency," Fourth International Conference on Vocal Fold Physiology, New Haven, Connecticut, June 3-6, 1985.) In this paper, we describe additional evidence for this type of nonlinear source-tract interaction in some soprano singing and describe an analogous interaction phenomenon in communication engineering. We also present some implications for voice research and pedagogy. Copyright © 2016 The Voice Foundation. Published by Elsevier Inc. All rights reserved.

  17. Youpi: YOUr processing PIpeline

    NASA Astrophysics Data System (ADS)

    Monnerville, Mathias; Sémah, Gregory

    2012-03-01

    Youpi is a portable, easy to use web application providing high level functionalities to perform data reduction on scientific FITS images. Built on top of various open source reduction tools released to the community by TERAPIX (http://terapix.iap.fr), Youpi can help organize data, manage processing jobs on a computer cluster in real time (using Condor) and facilitate teamwork by allowing fine-grain sharing of results and data. Youpi is modular and comes with plugins which perform, from within a browser, various processing tasks such as evaluating the quality of incoming images (using the QualityFITS software package), computing astrometric and photometric solutions (using SCAMP), resampling and co-adding FITS images (using SWarp) and extracting sources and building source catalogues from astronomical images (using SExtractor). Youpi is useful for small to medium-sized data reduction projects; it is free and is published under the GNU General Public License.

  18. Reporting the accuracy of biochemical measurements for epidemiologic and nutrition studies.

    PubMed

    McShane, L M; Clark, L C; Combs, G F; Turnbull, B W

    1991-06-01

    Procedures for reporting and monitoring the accuracy of biochemical measurements are presented. They are proposed as standard reporting procedures for laboratory assays for epidemiologic and clinical-nutrition studies. The recommended procedures require identification and estimation of all major sources of variability and explanations of laboratory quality control procedures employed. Variance-components techniques are used to model the total variability and calculate a maximum percent error that provides an easily understandable measure of laboratory precision accounting for all sources of variability. This avoids ambiguities encountered when reporting an SD that may taken into account only a few of the potential sources of variability. Other proposed uses of the total-variability model include estimating precision of laboratory methods for various replication schemes and developing effective quality control-checking schemes. These procedures are demonstrated with an example of the analysis of alpha-tocopherol in human plasma by using high-performance liquid chromatography.

  19. Accuracy, image quality, and radiation dose of prospectively ECG-triggered high-pitch dual-source CT angiography in infants and children with complex coarctation of the aorta.

    PubMed

    Xu, Jian; Zhao, Hongliang; Wang, Xiaoying; Bai, Yuxiang; Liu, Liwen; Liu, Ying; Wei, Mengqi; Li, Jian; Zheng, Minwen

    2014-10-01

    To evaluate the diagnostic accuracy, image quality, and radiation dose of prospective electrocardiogram (ECG)-triggered high-pitch dual-source computed tomography (DSCT) in infants and young children with complex coarctation of the aorta (CoA). Forty pediatric patients aged < 4 years with suspected CoA underwent prospective ECG-triggered high-pitch DSCT angiography and transthoracic echocardiography (TTE). Surgery and/or conventional cardiac angiography (CCA) were performed in all patients. The diagnostic accuracy of DSCT angiography and TTE was compared to the surgical and/or CCA findings. The causes of misdiagnosis and miss were analyzed, and the advantages and limitation of both imaging modalities were evaluated. Image quality of DSCT was evaluated, and effective radiation dose was calculated. The sensitivity, specificity, positive predictive value, negative predictive value, and overall diagnostic accuracy of DSCT in evaluation of complex CoA were 92.37%, 98.51%, 97.32%, 93.57%, and 96.25%, respectively. There was a significant difference in the accuracy between DSCT and TTE (χ² = 9.9, P<.05). For a total of 80 extracardiac anomalies, the sensitivity (98.8%, 79/80) of DSCT was greater than that of TTE (62.5%; 50 of 80). On the contrary, for 38 cardiac anomalies, the sensitivity (78.9%, 30 of 38) of DSCT was lesser than that of TTE (100%; 38 of 38). The mean score of image quality was 4.27 ± 0.73. The mean effective radiation dose was 0.20 ± 0.09 mSv. Prospective ECG-triggered high-pitch DSCT may be a clinical feasible modality in the evaluation of pediatric patients with complex CoA, providing adequate image quality, high diagnostic accuracy, and low radiation dose. Copyright © 2014 AUR. Published by Elsevier Inc. All rights reserved.

  20. Follow-up of coronary artery bypass graft patency: diagnostic efficiency of high-pitch dual-source 256-slice MDCT findings.

    PubMed

    Yuceler, Zeyneb; Kantarci, Mecit; Yuce, Ihsan; Kizrak, Yesim; Bayraktutan, Ummugulsum; Ogul, Hayri; Kiris, Adem; Celik, Omer; Pirimoglu, Berhan; Genc, Berhan; Gundogdu, Fuat

    2014-01-01

    Our aim was to evaluate the diagnostic accuracy of 256-slice, high-pitch mode multidetector computed tomography (MDCT) for coronary artery bypass graft (CABG) patency. Eighty-eight patients underwent 256-slice MDCT angiography to evaluate their graft patency after CABG surgery using a prospectively synchronized electrocardiogram in the high-pitch spiral acquisition mode. Effective radiation doses were calculated. We investigated the diagnostic accuracy of high-pitch, low-dose, prospective, electrocardiogram-triggering, dual-source MDCT for CABG patency compared with catheter coronary angiography imaging findings. A total of 215 grafts and 645 vessel segments were analyzed. All graft segments had diagnostic image quality. The proximal and middle graft segments had significantly (P < 0.05) better mean image quality scores (1.18 ± 0.4) than the distal segments (1.31 ± 0.5). Using catheter coronary angiography as the reference standard, high-pitch MDCT had the following sensitivity, specificity, positive predictive value, and negative predictive value of per-segment analysis for detecting graft patency: 97.1%, 99.6%, 94.4%, and 99.8%, respectively. In conclusion, MDCT can be used noninvasively with a lower radiation dose for the assessment of restenosis in CABG patients.

  1. Laser technologies for ultrasensitive groundwater dating using long-lived isotopes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Backus, Sterling

    In this phase I work, we propose to construct and demonstrate a 103 nm laser based on resonantly enhanced and phase matched fifth harmonic generation in hollow waveguides driven by a high power, low cost and compact ultrafast fiber laser. (Figure 4) This VUV laser source can potentially produce >100 milliwatts of VUV light at 103 nm with pulse repetition-rates of 100 kHz to 100 MHz, ideal for the above-mentioned applications. This technology is state-of-the-art and potentially compact, fieldable, low-cost, and of broad interest for a variety of science and technology applications. Laser-based VUV sources in the past have exhibitedmore » low repetition rate, low efficiency, low beam quality, and are based on expensive laser sources. Our approch is to combine ultrafast fiber laser drive technology, ultrafast pulses, and our proven waveguide technology, to create a high repetition rate, high average power VUV source for producing high yield metastable Krypton. At KMLabs we have been offering EUV light sources employing the high harmonic generation (HHG) process driven by high-power femtosecond lasers for >5 years now. Recently, we have developed much smaller scale (briefcase size), but still high average power femtosecond fiber laser sources to supply other markets, and create new ones. By combining these new laser sources with our patented waveguide frequency upconversion technology, we expect to be able to obtain >20mW average power initially, with potentially much higher powers depending on wavelength, in an affordable VUV product. For comparison, our current EUV light sources based on ti:sapphire generate an average power of ~5 µW (albeit at shorter 29 nm wavelength), and we are aware of one other supplier that has developed a VUV (112 nm) light source with ~10-20 µW power.« less

  2. Chemometric evaluation of nitrate contamination in the groundwater of a hard rock area in Dharapuram, south India

    NASA Astrophysics Data System (ADS)

    Sajil Kumar, P. J.; Jegathambal, P.; James, E. J.

    2014-12-01

    This paper presents the results of investigations on groundwater nitrate contamination in the Dharapuram area of Tamil Nadu in south India as a primary step to initiate denitrification. Groundwater samples were collected from 26 selected locations during the pre-monsoon season in July 2010 and analysed for nitrate and other water quality parameters. Two important water types were identified, viz. Ca-Na-HCO3 and mixed Ca-Mg-Cl. It is found that the majority of samples possess high nitrate concentration; 57 % of samples exceeded the permissible limit of Indian (45 mg/L) and WHO (50 mg/L) drinking water standard. Spatial distribution map of NO3 suggested that major contamination was observed in the SW and NW parts of the study area. This result was in agreement with the corresponding land-use pattern in this study area. Denitrification process at greater depths was evident from the negative correlation between NO3 and well depth. The sources and controlling factors of high nitrate were investigated using cross plots of NO3 with other selected hydrochemical parameters. Positive correlation for NO3 was observed with EC, K, Cl and SO4. This analysis was capable of differentiating the various sources of nitrate in groundwater. The major sources of nitrate contamination are identified as areas of high fertilizer application, sewages and animal waste dumping yards. Regulation of these pollutant sources with appropriate and cost-effective denitrification process can restore the water quality in this area.

  3. Assessment of hydrogeologic terrains, well-construction characteristics, groundwater hydraulics, and water-quality and microbial data for determination of surface-water-influenced groundwater supplies in West Virginia

    USGS Publications Warehouse

    Kozar, Mark D.; Paybins, Katherine S.

    2016-08-30

    Groundwater public-supply systems in areas of high intrinsic susceptibility and with a large number of potential contaminant sources within the recharge or source-water-protection area of individual wells or well fields are potentially vulnerable to contamination and probably warrant further evaluation as potential SWIGS. However, measures can be taken to educate the local population and initiate safety protocols and protective strategies to appropriately manage contaminant sources to prevent release of contaminants to the aquifer, therefore, reducing vulnerability of these systems to contamination. However, each public groundwater supply source needs to be assessed on an individual basis. Data presented in this report can be used to categorize and prioritize wells and springs that have a high potential for intrinsic susceptibility or vulnerability to contamination.

  4. Environmental evaluation of high-value agricultural produce with diverse water sources: case study from Southern California

    NASA Astrophysics Data System (ADS)

    Bell, Eric M.; Stokes-Draut, Jennifer R.; Horvath, Arpad

    2018-02-01

    Meeting agricultural demand in the face of a changing climate will be one of the major challenges of the 21st century. California is the single largest agricultural producer in the United States but is prone to extreme hydrologic events, including multi-year droughts. Ventura County is one of California’s most productive growing regions but faces water shortages and deteriorating water quality. The future of California’s agriculture is dependent on our ability to identify and implement alternative irrigation water sources and technologies. Two such alternative water sources are recycled and desalinated water. The proximity of high-value crops in Ventura County to both dense population centers and the Pacific Ocean makes it a prime candidate for alternative water sources. This study uses highly localized spatial and temporal data to assess life-cycle energy use, life-cycle greenhouse gas emissions, operational costs, applied water demand, and on-farm labor requirements for four high-value crops. A complete switch from conventional irrigation with groundwater and surface water to recycled water would increase the life-cycle greenhouse gas emissions associated with strawberry, lemon, celery, and avocado production by approximately 14%, 7%, 59%, and 9%, respectively. Switching from groundwater and surface water to desalinated water would increase life-cycle greenhouse gas emissions by 33%, 210%, 140%, and 270%, respectively. The use of recycled or desalinated water for irrigation is most financially tenable for strawberries due to their relatively high value and close proximity to water treatment facilities. However, changing strawberry packaging has a greater potential impact on life-cycle energy use and greenhouse gas emissions than switching the water source. While this analysis does not consider the impact of water quality on crop yields, previous studies suggest that switching to recycled water could result in significant yield increases due to its lower salinity.

  5. Impact of emissions from natural gas production facilities on ambient air quality in the Barnett Shale area: a pilot study.

    PubMed

    Zielinska, Barbara; Campbell, Dave; Samburova, Vera

    2014-12-01

    Rapid and extensive development of shale gas resources in the Barnett Shale region of Texas in recent years has created concerns about potential environmental impacts on water and air quality. The purpose of this study was to provide a better understanding of the potential contributions of emissions from gas production operations to population exposure to air toxics in the Barnett Shale region. This goal was approached using a combination of chemical characterization of the volatile organic compound (VOC) emissions from active wells, saturation monitoring for gaseous and particulate pollutants in a residential community located near active gas/oil extraction and processing facilities, source apportionment of VOCs measured in the community using the Chemical Mass Balance (CMB) receptor model, and direct measurements of the pollutant gradient downwind of a gas well with high VOC emissions. Overall, the study results indicate that air quality impacts due to individual gas wells and compressor stations are not likely to be discernible beyond a distance of approximately 100 m in the downwind direction. However, source apportionment results indicate a significant contribution to regional VOCs from gas production sources, particularly for lower-molecular-weight alkanes (< C6). Although measured ambient VOC concentrations were well below health-based safe exposure levels, the existence of urban-level mean concentrations of benzene and other mobile source air toxics combined with soot to total carbon ratios that were high for an area with little residential or commercial development may be indicative of the impact of increased heavy-duty vehicle traffic related to gas production. Implications: Rapid and extensive development of shale gas resources in recent years has created concerns about potential environmental impacts on water and air quality. This study focused on directly measuring the ambient air pollutant levels occurring at residential properties located near natural gas extraction and processing facilities, and estimating the relative contributions from gas production and motor vehicle emissions to ambient VOC concentrations. Although only a small-scale case study, the results may be useful for guidance in planning future ambient air quality studies and human exposure estimates in areas of intensive shale gas production.

  6. The development of a tunable, single-frequency ultraviolet laser source for UV filtered Rayleigh scattering

    NASA Technical Reports Server (NTRS)

    Finkelstein, N.; Gambogi, J.; Lempert, Walter R.; Miles, Richard B.; Rines, G. A.; Finch, A.; Schwarz, R. A.

    1995-01-01

    We present the development of a flexible, high power, narrow line width, tunable ultraviolet source for diagnostic application. By frequency tripling the output of a pulsed titanium-sapphire laser, we achieve broadly tunable (227-360 nm) ultraviolet light with high quality spatial and spectral resolution. We also present the characterization of a mercury vapor cell which provides a narrow band, sharp edge absorption filter at 253.7 nm. These two components form the basis for the extension of the Filtered Rayleigh Scattering technique into the ultraviolet. The UV-FRS system is comprised of four pieces: a single frequency, cw tunable Ti:Sapphire seeding source; a high-powered pulsed Ti:Sapphire oscillator; a third harmonic generator system; and an atomic mercury vapor filter. In this paper we discuss the development and characterization of each of these elements.

  7. Experimental realization of underdense plasma photocathode wakefield acceleration at FACET

    NASA Astrophysics Data System (ADS)

    Scherkl, Paul

    2017-10-01

    Novel electron beam sources from compact plasma accelerator concepts currently mature into the driving technology for next generation high-energy physics and light source facilities. Particularly electron beams of ultra-high brightness could pave the way for major advances for both scientific and commercial applications, but their generation remains tremendously challenging. The presentation outlines the experimental demonstration of the world's first bright electron beam source from spatiotemporally synchronized laser pulses injecting electrons into particle-driven plasma wakefields at FACET. Two distinctive types of operation - laser-triggered density downramp injection (``Plasma Torch'') and underdense plasma photocathode acceleration (``Trojan Horse'') - and their intermediate transitions are characterized and contrasted. Extensive particle-in-cell simulations substantiate the presentation of experimental results. In combination with novel techniques to minimize the beam energy spread, the acceleration scheme presented here promises ultra-high beam quality and brightness.

  8. Fruit wastes fermentation for phenolic antioxidants production and their application in manufacture of edible coatings and films.

    PubMed

    Martinez-Avila, G C G; Aguilera, A F; Saucedo, S; Rojas, R; Rodriguez, R; Aguilar, C N

    2014-01-01

    Agro-industrial by-products are important sources of potent bioactive phenolic compounds. These compounds are of extreme relevance for food and pharmacological industries due to their great variety of biological activities. Fermentation represents an environmentally clean technology for production and extraction of these bioactive compounds, providing high quality and high activity extracts, which can be incorporated in foods using coatings/films wax-based in order to avoid alterations in their quality. In this document is presented an overview about importance and benefits of solid-state fermentation, pointing out this bioprocess as an alternative technology for use agro-industrial by-products as substrates to produce valuable secondary metabolites and their applications as food quality conservatives.

  9. Groundwater quality in the Basin and Range Basin-Fill Aquifers, southwestern United States

    USGS Publications Warehouse

    Musgrove, MaryLynn; Belitz, Kenneth

    2017-01-19

    Groundwater provides nearly 50 percent of the Nation’s drinking water. To help protect this vital resource, the U.S. Geological Survey (USGS) National Water-Quality Assessment (NAWQA) Project assesses groundwater quality in aquifers that are important sources of drinking water. The Basin and Range basin-fill aquifers constitute one of the important areas being evaluated. One or more inorganic constituents with human-health benchmarks were detected at high concentrations in about 20 percent of the study area and at moderate concentrations in about 49 percent. Organic constituents were not detected at high concentrations in the study area. One or more organic constituents with human-health benchmarks were detected at moderate concentrations in about 3 percent of the study area.

  10. Isolation of high-quality total RNA from leaves of Myrciaria dubia "CAMU CAMU".

    PubMed

    Gómez, Juan Carlos Castro; Reátegui, Alina Del Carmen Egoavil; Flores, Julián Torres; Saavedra, Roberson Ramírez; Ruiz, Marianela Cobos; Correa, Sixto Alfredo Imán

    2013-01-01

    Myrciaria dubia is a main source of vitamin C for people in the Amazon region. Molecular studies of M. dubia require high-quality total RNA from different tissues. So far, no protocols have been reported for total RNA isolation from leaves of this species. The objective of this research was to develop protocols for extracting high-quality total RNA from leaves of M. dubia. Total RNA was purified following two modified protocols developed for leaves of other species (by Zeng and Yang, and by Reid et al.) and one modified protocol developed for fruits of the studied species (by Silva). Quantity and quality of purified total RNA were assessed by spectrophotometric and electrophoretic analysis. Additionally, quality of total RNA was evaluated with reverse-transcription polymerase chain reaction (RT-PCR). With these three modified protocols we were able to isolate high-quality RNA (A260nm/A280nm >1.9 and A260nm/A230nm >2.0). Highest yield was produced with the Zeng and Yang modified protocol (384±46µg ARN/g fresh weight). Furthermore, electrophoretic analysis showed the integrity of isolated RNA and the absence of DNA. Another proof of the high quality of our purified RNA was the successful cDNA synthesis and amplification of a segment of the M. dubia actin 1 gene. We report three modified protocols for isolation total RNA from leaves of M. dubia. The modified protocols are easy, rapid, low in cost, and effective for high-quality and quantity total RNA isolation suitable for cDNA synthesis and polymerase chain reaction.

  11. Electrochemiluminescence immunosorbent assay of ricin in ground beef: Biotinylated capture antibodies and matrix effects

    USDA-ARS?s Scientific Manuscript database

    Ricin is a highly toxic protein present in the seeds of castor (Ricinus communis), grown principally as a source of high quality industrial lubricant and as an ornamental. Because of the past use of ricin for intentional poisoning, there is a need for analytical methodology to detect ricin in food m...

  12. Engineering High Assurance Distributed Cyber Physical Systems

    DTIC Science & Technology

    2015-01-15

    decisions: number of interacting agents and co-dependent decisions made in real-time without causing interference . To engineer a high assurance DART...environment specification, architecture definition, domain-specific languages, design patterns, code - generation, analysis, test-generation, and simulation...include synchronization between the models and source code , debugging at the model level, expression of the design intent, and quality of service

  13. The Impact of Collective Bargaining on Teacher Transfer Rates in Urban High-Poverty Schools

    ERIC Educational Resources Information Center

    Nelson, F. Howard

    2006-01-01

    Data in this report reveals that collectively bargaining agreements are not the source of the teacher quality problem in urban school districts. The data shows that collective bargaining agreements are associated with reduced teacher transfer activity, especially in high-poverty schools, and less reliance on first-year teachers to staff…

  14. Phenotype analysis of Russian dandelion root tissues from the national plant germplasm system collection

    USDA-ARS?s Scientific Manuscript database

    Russian dandelion (Taraxacum kok-saghyz) (TKS) produces high quality natural rubber (NR), cis-1,4 polyisoprene, by biosynthesis, and has been used historically as a source of NR during times of short supply or high prices for Hevea NR. The rubber is primarily located in root tissues along with appre...

  15. Realization of Culture in English Textbooks in Chinese High School Level

    ERIC Educational Resources Information Center

    Aliakbari, Mohammad; Jamalvandi, Behrouz

    2012-01-01

    This study reflects on the presentation of culture in the English textbooks adopted in Chinese high school level. The categorization by Ramirez and Hall (1990) shaped the basis of the textbook analysis. The main objectives of the inquiry were to examine the quality of representation of source, target and other cultures in the ELT textbooks.…

  16. Laser ion source for heavy ion inertial fusion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Okamura, Masahiro

    The proposed heavy ion inertial fusion (HIF) scenarios require ampere class low charge state ion beams of heavy species. A laser ion source (LIS) is recognized as one of the promising candidates of ion beam providers, since it can deliver high brightness heavy ion beams to accelerators. A design of LIS for the HIF depends on the accelerator structure and accelerator complex following the source. In this article, we discuss the specifications and design of an appropriate LIS assuming two major types of the accelerators: radio frequency (RF) high quality factor cavity type and non-resonant induction core type. We believemore » that a properly designed LIS satisfies the requirements of both types, however some issues need to be verified experimentally.« less

  17. Laser ion source for heavy ion inertial fusion

    DOE PAGES

    Okamura, Masahiro

    2018-01-10

    The proposed heavy ion inertial fusion (HIF) scenarios require ampere class low charge state ion beams of heavy species. A laser ion source (LIS) is recognized as one of the promising candidates of ion beam providers, since it can deliver high brightness heavy ion beams to accelerators. A design of LIS for the HIF depends on the accelerator structure and accelerator complex following the source. In this article, we discuss the specifications and design of an appropriate LIS assuming two major types of the accelerators: radio frequency (RF) high quality factor cavity type and non-resonant induction core type. We believemore » that a properly designed LIS satisfies the requirements of both types, however some issues need to be verified experimentally.« less

  18. Local-Scale Air Quality Modeling in Support of Human Health and Exposure Research (Invited)

    NASA Astrophysics Data System (ADS)

    Isakov, V.

    2010-12-01

    Spatially- and temporally-sparse information on air quality is a key concern for air-pollution-related environmental health studies. Monitor networks are sparse in both space and time, are costly to maintain, and are often designed purposely to avoid detecting highly localized sources. Recent studies have shown that more narrowly defining the geographic domain of the study populations and improvements in the measured/estimated ambient concentrations can lead to stronger associations between air pollution and hospital admissions and mortality records. Traditionally, ambient air quality measurements have been used as a primary input to support human health and exposure research. However, there is increasing evidence that the current ambient monitoring network is not capturing sharp gradients in exposure due to the presence of high concentration levels near, for example, major roadways. Many air pollutants exhibit large concentration gradients near large emitters such as major roadways, factories, ports, etc. To overcome these limitations, researchers are now beginning to use air quality models to support air pollution exposure and health studies. There are many advantages to using air quality models over traditional approaches based on existing ambient measurements alone. First, models can provide spatially- and temporally-resolved concentrations as direct input to exposure and health studies and thus better defining the concentration levels for the population in the geographic domain. Air quality models have a long history of use in air pollution regulations, and supported by regulatory agencies and a large user community. Also, models can provide bidirectional linkages between sources of emissions and ambient concentrations, thus allowing exploration of various mitigation strategies to reduce risk to exposure. In order to provide best estimates of air concentrations to support human health and exposure studies, model estimates should consider local-scale features, regional-scale transport, and photochemical transformations. Since these needs are currently not met by a single model, hybrid air quality modeling has recently been developed to combine these capabilities. In this paper, we present the results of two studies where we applied the hybrid modeling approach to provide spatial and temporal details in air quality concentrations to support exposure and health studies: a) an urban-scale air quality accountability study involving near-source exposures to multiple ambient air pollutants, and b) an urban-scale epidemiological study involving human health data based on emergency department visits.

  19. Ultrafast electron diffraction optimized for studying structural dynamics in thin films and monolayers

    PubMed Central

    Badali, D. S.; Gengler, R. Y. N.; Miller, R. J. D.

    2016-01-01

    A compact electron source specifically designed for time-resolved diffraction studies of free-standing thin films and monolayers is presented here. The sensitivity to thin samples is achieved by extending the established technique of ultrafast electron diffraction to the “medium” energy regime (1–10 kV). An extremely compact design, in combination with low bunch charges, allows for high quality diffraction in a lensless geometry. The measured and simulated characteristics of the experimental system reveal sub-picosecond temporal resolution, while demonstrating the ability to produce high quality diffraction patterns from atomically thin samples. PMID:27226978

  20. Production and use of estimates for monitoring progress in the health sector: the case of Bangladesh

    PubMed Central

    Ahsan, Karar Zunaid; Tahsina, Tazeen; Iqbal, Afrin; Ali, Nazia Binte; Chowdhury, Suman Kanti; Huda, Tanvir M.; Arifeen, Shams El

    2017-01-01

    ABSTRACT Background: In order to support the progress towards the post-2015 development agenda for the health sector, the importance of high-quality and timely estimates has become evident both globally and at the country level. Objective and Methods: Based on desk review, key informant interviews and expert panel discussions, the paper critically reviews health estimates from both the local (i.e. nationally generated information by the government and other agencies) and the global sources (which are mostly modeled or interpolated estimates developed by international organizations based on different sources of information), and assesses the country capacity and monitoring strategies to meet the increasing data demand in the coming years. Primarily, this paper provides a situation analysis of Bangladesh in terms of production and use of health estimates for monitoring progress towards the post-2015 development goals for the health sector. Results: The analysis reveals that Bangladesh is data rich, particularly from household surveys and health facility assessments. Practices of data utilization also exist, with wide acceptability of survey results for informing policy, programme review and course corrections. Despite high data availability from multiple sources, the country capacity for providing regular updates of major global health estimates/indicators remains low. Major challenges also include limited human resources, capacity to generate quality data and multiplicity of data sources, where discrepancy and lack of linkages among different data sources (local sources and between local and global estimates) present emerging challenges for interpretation of the resulting estimates. Conclusion: To fulfill the increased data requirement for the post-2015 era, Bangladesh needs to invest more in electronic data capture and routine health information systems. Streamlining of data sources, integration of parallel information systems into a common platform, and capacity building for data generation and analysis are recommended as priority actions for Bangladesh in the coming years. In addition to automation of routine health information systems, establishing an Indicator Reference Group for Bangladesh to analyze data; building country capacity in data quality assessment and triangulation; and feeding into global, inter-agency estimates for better reporting would address a number of mentioned challenges in the short- and long-run. PMID:28532305

  1. GENERATING HIGH QUALITY IMPERVIOUS COVER DATA

    EPA Science Inventory

    Nonpoint source pollution (NPS) from urban/ suburban areas is rapidly increasing as the population increases in the United States. Research in recent years has consistently shown a strong relationship between the percentage of impervious cover in a drainage basin and the health...

  2. Scenedesmus incrassatulus CLHE-Si01: a potential source of renewable lipid for high quality biodiesel production.

    PubMed

    Arias-Peñaranda, Martha T; Cristiani-Urbina, Eliseo; Montes-Horcasitas, Carmen; Esparza-García, Fernando; Torzillo, Giuseppe; Cañizares-Villanueva, Rosa Olivia

    2013-07-01

    The potential of microalgal oil from Scenedesmus incrassatulus as a feedstock for biodiesel production was studied. Cell concentration of S. incrassatulus and lipid content obtained during mixotrophic growth were 1.8 g/L and 19.5 ± 1.5% dry cell weight, respectively. The major components of biodiesel obtained from S. incrassatulus oil were methyl palmitate (26%) and methyl linoleate (49%), which provided a strong indication of high quality biodiesel. Fuel properties were determined by empirical equations and found to be within the limits of biodiesel standard ASTM D6751 and EN 14214. The quality properties of the biodiesel were high cetane number (62), low density (803 kg/m(3)), low viscosity (3.78 mm(2)/s), oxidation stability (9h) and cold filter plugging point (-4°C). Hence, S. incrassatulus has potential as a feedstock for the production of excellent quality biodiesel. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. For Video Games, Bad News Is Good News: News Reporting of Violent Video Game Studies.

    PubMed

    Copenhaver, Allen; Mitrofan, Oana; Ferguson, Christopher J

    2017-12-01

    News coverage of video game violence studies has been critiqued for focusing mainly on studies supporting negative effects and failing to report studies that did not find evidence for such effects. These concerns were tested in a sample of 68 published studies using child and adolescent samples. Contrary to our hypotheses, study effect size was not a predictor of either newspaper coverage or publication in journals with a high-impact factor. However, a relationship between poorer study quality and newspaper coverage approached significance. High-impact journals were not found to publish studies with higher quality. Poorer quality studies, which tended to highlight negative findings, also received more citations in scholarly sources. Our findings suggest that negative effects of violent video games exposure in children and adolescents, rather than large effect size or high methodological quality, increase the likelihood of a study being cited in other academic publications and subsequently receiving news media coverage.

  4. Impact of landscape disturbance on the quality of terrestrial sediment carbon in temperate streams

    NASA Astrophysics Data System (ADS)

    Fox, James F.; Ford, William I.

    2016-09-01

    Recent studies have shown the super saturation of fluvial networks with respect to carbon dioxide, and the concept that the high carbon dioxide is at least partially the result of turnover of sediment organic carbon that ranges in age from years to millennia. Currently, there is a need for more highly resolved studies at stream and river scales that enable estimates of terrestrial carbon turnover within fluvial networks. Our objective was to develop a new isotope-based metric to estimate the quality of sediment organic carbon delivered to temperate streams and to use the new metric to estimate carbon quality across landscape disturbance gradients. Carbon quality is defined to be consistent with in-stream turnover and our metric is used to measure the labile or recalcitrant nature of the terrestrial-derived carbon within streams. Our hypothesis was that intensively-disturbed landscapes would tend to produce low quality carbon because deep, recalcitrant soil carbon would be eroded and transported to the fluvial system while moderately disturbed or undisturbed landscapes would tend to produce higher quality carbon from well-developed surface soils and litter. The hypothesis was tested by applying the new carbon quality metric to 15 temperate streams with a wide range of landscape disturbance levels. We find that our hypothesis premised on an indirect relationship between the extent of landscape disturbance and the quality of sediment carbon in streams holds true for moderate and high disturbances but not for un-disturbed forests. We explain the results based on the connectivity, or dis-connectivity, between terrestrial carbon sources and pathways for sediment transport. While pathways are typically un-limited for disturbed landscapes, the un-disturbed forests have dis-connectivity between labile carbon of the forest floor and the stream corridor. Only in the case when trees fell into the stream corridor due to severe ice storms did the quality of sediment carbon increase in the streams. We argue that as scientists continue to estimate the in-stream turnover of terrestrially-derived carbon in fluvial carbon budgets, the assumption of pathway connectivity between carbon sources to the stream should be justified.

  5. Wildfire effects on source-water quality--Lessons from Fourmile Canyon fire, Colorado, and implications for drinking-water treatment

    USGS Publications Warehouse

    Writer, Jeffrey H.; Murphy, Sheila F.

    2012-01-01

    Forested watersheds provide high-quality source water for many communities in the western United States. These watersheds are vulnerable to wildfires, and wildfire size, fire severity, and length of fire season have increased since the middle 1980s (Westerling and others, 2006). Burned watersheds are prone to increased flooding and erosion, which can impair water-supply reservoirs, water quality, and drinking-water treatment processes. Limited information exists on the degree, timing, and duration of the effects of wildfire on water quality, making it difficult for drinking-water providers to evaluate the risk and develop management options. In order to evaluate the effects of wildfire on water quality and downstream ecosystems in the Colorado Front Range, the U.S. Geological Survey initiated a study after the 2010 Fourmile Canyon fire near Boulder, Colorado. Hydrologists frequently sampled Fourmile Creek at monitoring sites upstream and downstream of the burned area to study water-quality changes during hydrologic conditions such as base flow, spring snowmelt, and summer thunderstorms. This fact sheet summarizes principal findings from the first year of research. Stream discharge and nitrate concentrations increased downstream of the burned area during snowmelt runoff, but increases were probably within the treatment capacity of most drinking-water plants, and limited changes were observed in downstream ecosystems. During and after high-intensity thunderstorms, however, turbidity, dissolved organic carbon, nitrate, and some metals increased by 1 to 4 orders of magnitude within and downstream of the burned area. Increases of such magnitude can pose problems for water-supply reservoirs, drinking-water treatment plants, and downstream aquatic ecosystems.

  6. Synthesis and surface chemistry of high quality wurtzite and kesterite Cu2ZnSnS4 nanocrystals using tin(II) 2-ethylhexanoate as a new tin source.

    PubMed

    Gabka, Grzegorz; Bujak, Piotr; Gryszel, Maciej; Ostrowski, Andrzej; Malinowska, Karolina; Zukowska, Grazyna Z; Agnese, Fabio; Pron, Adam; Reiss, Peter

    2015-08-21

    A novel synthesis method for the preparation of Cu2ZnSnS4 nanocrystals is presented using a liquid precursor of tin, namely tin(II) 2-ethylhexanoate, which yields small and nearly monodisperse NCs either in the kesterite or in the wurtzite phase depending on the sulfur source (elemental sulfur in oleylamine vs. dodecanethiol).

  7. Normalization and standardization of electronic health records for high-throughput phenotyping: the SHARPn consortium

    PubMed Central

    Pathak, Jyotishman; Bailey, Kent R; Beebe, Calvin E; Bethard, Steven; Carrell, David S; Chen, Pei J; Dligach, Dmitriy; Endle, Cory M; Hart, Lacey A; Haug, Peter J; Huff, Stanley M; Kaggal, Vinod C; Li, Dingcheng; Liu, Hongfang; Marchant, Kyle; Masanz, James; Miller, Timothy; Oniki, Thomas A; Palmer, Martha; Peterson, Kevin J; Rea, Susan; Savova, Guergana K; Stancl, Craig R; Sohn, Sunghwan; Solbrig, Harold R; Suesse, Dale B; Tao, Cui; Taylor, David P; Westberg, Les; Wu, Stephen; Zhuo, Ning; Chute, Christopher G

    2013-01-01

    Research objective To develop scalable informatics infrastructure for normalization of both structured and unstructured electronic health record (EHR) data into a unified, concept-based model for high-throughput phenotype extraction. Materials and methods Software tools and applications were developed to extract information from EHRs. Representative and convenience samples of both structured and unstructured data from two EHR systems—Mayo Clinic and Intermountain Healthcare—were used for development and validation. Extracted information was standardized and normalized to meaningful use (MU) conformant terminology and value set standards using Clinical Element Models (CEMs). These resources were used to demonstrate semi-automatic execution of MU clinical-quality measures modeled using the Quality Data Model (QDM) and an open-source rules engine. Results Using CEMs and open-source natural language processing and terminology services engines—namely, Apache clinical Text Analysis and Knowledge Extraction System (cTAKES) and Common Terminology Services (CTS2)—we developed a data-normalization platform that ensures data security, end-to-end connectivity, and reliable data flow within and across institutions. We demonstrated the applicability of this platform by executing a QDM-based MU quality measure that determines the percentage of patients between 18 and 75 years with diabetes whose most recent low-density lipoprotein cholesterol test result during the measurement year was <100 mg/dL on a randomly selected cohort of 273 Mayo Clinic patients. The platform identified 21 and 18 patients for the denominator and numerator of the quality measure, respectively. Validation results indicate that all identified patients meet the QDM-based criteria. Conclusions End-to-end automated systems for extracting clinical information from diverse EHR systems require extensive use of standardized vocabularies and terminologies, as well as robust information models for storing, discovering, and processing that information. This study demonstrates the application of modular and open-source resources for enabling secondary use of EHR data through normalization into standards-based, comparable, and consistent format for high-throughput phenotyping to identify patient cohorts. PMID:24190931

  8. Affordable and accurate large-scale hybrid-functional calculations on GPU-accelerated supercomputers

    NASA Astrophysics Data System (ADS)

    Ratcliff, Laura E.; Degomme, A.; Flores-Livas, José A.; Goedecker, Stefan; Genovese, Luigi

    2018-03-01

    Performing high accuracy hybrid functional calculations for condensed matter systems containing a large number of atoms is at present computationally very demanding or even out of reach if high quality basis sets are used. We present a highly optimized multiple graphics processing unit implementation of the exact exchange operator which allows one to perform fast hybrid functional density-functional theory (DFT) calculations with systematic basis sets without additional approximations for up to a thousand atoms. With this method hybrid DFT calculations of high quality become accessible on state-of-the-art supercomputers within a time-to-solution that is of the same order of magnitude as traditional semilocal-GGA functionals. The method is implemented in a portable open-source library.

  9. High Performance OLED Panel and Luminaire

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Spindler, Jeffrey

    2017-02-20

    In this project, OLEDWorks developed and demonstrated the technology required to produce OLED lighting panels with high energy efficiency and excellent light quality. OLED panels developed in this program produce high quality warm white light with CRI greater than 85 and efficacy up to 80 lumens per watt (LPW). An OLED luminaire employing 24 of the high performance panels produces practical levels of illumination for general lighting, with a flux of over 2200 lumens at 60 LPW. This is a significant advance in the state of the art for OLED solid-state lighting (SSL), which is expected to be a complementarymore » light source to the more advanced LED SSL technology that is rapidly replacing all other traditional forms of lighting.« less

  10. Effects of the addition of different nitrogen sources in the tequila fermentation process at high sugar concentration.

    PubMed

    Arrizon, J; Gschaedler, A

    2007-04-01

    To study the effect of the addition of different nitrogen sources at high sugar concentration in the tequila fermentation process. Fermentations were performed at high sugar concentration (170 g l(-1)) using Agave tequilana Weber blue variety with and without added nitrogen from different sources (ammonium sulfate; glutamic acid; a mixture of ammonium sulfate and amino acids) during the exponential phase of growth. All the additions increased the fermentation rate and alcohol efficiency. The level of synthesis of volatile compounds depended on the source added. The concentration of amyl alcohols and isobutanol were decreased while propanol and acetaldehyde concentration increased. The most efficient nitrogen sources for fermentation rate were ammonium sulfate and the mixture of ammonium sulfate and amino acids. The level of volatile compounds produced depended upon types of nitrogen. The synthesis of some volatile compounds increased while others decreased with nitrogen addition. The addition of nitrogen could be a strategy for improving the fermentation rate and efficiency in the tequila fermentation process at high sugar Agave tequilana concentration. Furthermore, the sensory quality of the final product may change because the synthesis of the volatile compounds is modified.

  11. High power narrow-band fiber-based ASE source.

    PubMed

    Schmidt, O; Rekas, M; Wirth, C; Rothhardt, J; Rhein, S; Kliner, A; Strecker, M; Schreiber, T; Limpert, J; Eberhardt, R; Tünnermann, A

    2011-02-28

    In this paper we describe a high power narrow-band amplified spontaneous emission (ASE) light source at 1030 nm center wavelength generated in an Yb-doped fiber-based experimental setup. By cutting a small region out of a broadband ASE spectrum using two fiber Bragg gratings a strongly constrained bandwidth of 12±2 pm (3.5±0.6 GHz) is formed. A two-stage high power fiber amplifier system is used to boost the output power up to 697 W with a measured beam quality of M2≤1.34. In an additional experiment we demonstrate a stimulated Brillouin scattering (SBS) suppression of at least 17 dB (theoretically predicted ~20 dB), which is only limited by the dynamic range of the measurement and not by the onset of SBS when using the described light source. The presented narrow-band ASE source could be of great interest for brightness scaling applications by beam combination, where SBS is known as a limiting factor.

  12. Quality of our groundwater resources: Arsenic and fluoride

    USGS Publications Warehouse

    Nordstrom, D. Kirk

    2011-01-01

    Groundwater often contains arsenic or fluoride concentrations too high for drinking or cooking. These constituents, often naturally occurring, are not easy to remove. The right combination of natural or manmade conditions can lead to elevated arsenic or fluoride which includes continental source rocks, high alkalinity and pH, reducing conditions for arsenic, high phosphate, high temperature and high silica. Agencies responsible for safe drinking water should be aware of these conditions, be prepared to monitor, and treat if necessary.

  13. Understanding Public Views about Air Quality and Air Pollution Sources in the San Joaquin Valley, California.

    PubMed

    Cisneros, Ricardo; Brown, Paul; Cameron, Linda; Gaab, Erin; Gonzalez, Mariaelena; Ramondt, Steven; Veloz, David; Song, Anna; Schweizer, Don

    2017-01-01

    The San Joaquin Valley of California has poor air quality and high rates of asthma. Surveys were collected from 744 residents of the San Joaquin Valley from November 2014 to January 2015 to examine the public's views about air quality. The results of this study suggest that participants exposed to high PM 2.5 (particulate matter less than 2.5 microns in size) concentrations perceived air pollution to be of the worst quality. Air quality in the San Joaquin Valley was primarily perceived as either moderate or unhealthy for sensitive groups. Females perceived air pollution to be of worse quality compared to males. Participants perceived unemployment, crime, and obesity to be the top three most serious community problems in the San Joaquin Valley. Participants viewed cars and trucks, windblown dust, and factories as the principle contributors to air pollution in the area. There is a need to continue studying public perceptions of air quality in the San Joaquin Valley with a more robust survey with more participants over several years and seasons.

  14. Understanding Public Views about Air Quality and Air Pollution Sources in the San Joaquin Valley, California

    PubMed Central

    Brown, Paul; Cameron, Linda; Gaab, Erin; Gonzalez, Mariaelena; Ramondt, Steven; Veloz, David; Song, Anna; Schweizer, Don

    2017-01-01

    The San Joaquin Valley of California has poor air quality and high rates of asthma. Surveys were collected from 744 residents of the San Joaquin Valley from November 2014 to January 2015 to examine the public's views about air quality. The results of this study suggest that participants exposed to high PM2.5 (particulate matter less than 2.5 microns in size) concentrations perceived air pollution to be of the worst quality. Air quality in the San Joaquin Valley was primarily perceived as either moderate or unhealthy for sensitive groups. Females perceived air pollution to be of worse quality compared to males. Participants perceived unemployment, crime, and obesity to be the top three most serious community problems in the San Joaquin Valley. Participants viewed cars and trucks, windblown dust, and factories as the principle contributors to air pollution in the area. There is a need to continue studying public perceptions of air quality in the San Joaquin Valley with a more robust survey with more participants over several years and seasons. PMID:28469673

  15. Ozone Satellite Data Synergy and Combination with Non-satellite Data in the AURORA project

    NASA Astrophysics Data System (ADS)

    Cortesi, U.; Tirelli, C.; Arola, A.; Dragani, R.; Keppens, A.; Loenen, E.; Masini, A.; Tsiakos, , C.; van der A, R.; Verberne, K.

    2017-12-01

    The geostationary satellite constellation composed of TEMPO (North America), SENTINEL-4 (Europe) and GEMS (Asia) missions is a major instance of space component in the fundamentally new paradigm aimed at integrating information on air quality from a wide variety of sources. Space-borne data on tropospheric composition from new generation satellites have a growing impact in this context because of their unprecedented quantity and quality, while merging with non-satellite measurements and other types of auxiliary data via state-of-the-art modelling capabilities remains essential to fit the purpose of highly accurate information made readily available at high temporal and spatial resolution, both in analysis and forecast mode. Proper and effective implementation of this paradigm poses severe challenges to science, technology and applications that must be addressed in a closely interconnected manner to pave the way to high quality products and innovative services. Novel ideas and tools built on these three pillars are currently under investigation in the AURORA (Advanced Ultraviolet Radiation and Ozone Retrieval for Applications) Horizon 2020 project of the European Commission. The primary goal of the project is the proof of concept of a synergistic approach to the exploitation of Sentinel-4 and -5 Ozone measurements in the UV, Visible and Thermal Infrared based on the combination of an innovative data fusion method and assimilation models. The scientific objective shares the same level of priority with the technological effort to realize a prototype data processor capable to manage the full data processing chain and with the development of two downstream applications for demonstration purposes. The presentation offers a first insight in mid-term results of the project, which is mostly based on the use of synthetic data from the atmospheric Sentinels. Specific focus is given to the role of satellite data synergy in integrated systems for air quality monitoring, in particular when testing the impact of TEMPO and GEMS Ozone data in AURORA. As a further element relevant for the integration of multiple data sources, we describe the AIR-Portal application, which is going to combine AURORA partial columns of tropospheric ozone with other source of information for air quality analysis and forecast in metropolitan areas.

  16. SU-E-T-68: A Quality Assurance System with a Web Camera for High Dose Rate Brachytherapy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ueda, Y; Hirose, A; Oohira, S

    Purpose: The purpose of this work was to develop a quality assurance (QA) system for high dose rate (HDR) brachytherapy to verify the absolute position of an 192Ir source in real time and to measure dwell time and position of the source simultaneously with a movie recorded by a web camera. Methods: A web camera was fixed 15 cm above a source position check ruler to monitor and record 30 samples of the source position per second over a range of 8.0 cm, from 1425 mm to 1505 mm. Each frame had a matrix size of 480×640 in the movie.more » The source position was automatically quantified from the movie using in-house software (built with LabVIEW) that applied a template-matching technique. The source edge detected by the software on each frame was corrected to reduce position errors induced by incident light from an oblique direction. The dwell time was calculated by differential processing to displacement of the source. The performance of this QA system was illustrated by recording simple plans and comparing the measured dwell positions and time with the planned parameters. Results: This QA system allowed verification of the absolute position of the source in real time. The mean difference between automatic and manual detection of the source edge was 0.04 ± 0.04 mm. Absolute position error can be determined within an accuracy of 1.0 mm at dwell points of 1430, 1440, 1450, 1460, 1470, 1480, 1490, and 1500 mm, in three step sizes and dwell time errors, with an accuracy of 0.1% in more than 10.0 sec of planned time. The mean step size error was 0.1 ± 0.1 mm for a step size of 10.0 mm. Conclusion: This QA system provides quick verifications of the dwell position and time, with high accuracy, for HDR brachytherapy. This work was supported by the Japan Society for the Promotion of Science Core-to-Core program (No. 23003)« less

  17. Panama Canal Expansion Illustrates Need for Multimodal Near-Source Air Quality Assessment

    EPA Science Inventory

    The compelling issue raised is potential major changes in goods movement due to the Panama Canal expansion and considerations for near-source air quality. Near-source air quality may be affected both at near-port areas as well as along the freight transportation corridor.

  18. Point-source inversion techniques

    NASA Astrophysics Data System (ADS)

    Langston, Charles A.; Barker, Jeffrey S.; Pavlin, Gregory B.

    1982-11-01

    A variety of approaches for obtaining source parameters from waveform data using moment-tensor or dislocation point source models have been investigated and applied to long-period body and surface waves from several earthquakes. Generalized inversion techniques have been applied to data for long-period teleseismic body waves to obtain the orientation, time function and depth of the 1978 Thessaloniki, Greece, event, of the 1971 San Fernando event, and of several events associated with the 1963 induced seismicity sequence at Kariba, Africa. The generalized inversion technique and a systematic grid testing technique have also been used to place meaningful constraints on mechanisms determined from very sparse data sets; a single station with high-quality three-component waveform data is often sufficient to discriminate faulting type (e.g., strike-slip, etc.). Sparse data sets for several recent California earthquakes, for a small regional event associated with the Koyna, India, reservoir, and for several events at the Kariba reservoir have been investigated in this way. Although linearized inversion techniques using the moment-tensor model are often robust, even for sparse data sets, there are instances where the simplifying assumption of a single point source is inadequate to model the data successfully. Numerical experiments utilizing synthetic data and actual data for the 1971 San Fernando earthquake graphically demonstrate that severe problems may be encountered if source finiteness effects are ignored. These techniques are generally applicable to on-line processing of high-quality digital data, but source complexity and inadequacy of the assumed Green's functions are major problems which are yet to be fully addressed.

  19. Chemical quality and regulatory compliance of drinking water in Iceland.

    PubMed

    Gunnarsdottir, Maria J; Gardarsson, Sigurdur M; Jonsson, Gunnar St; Bartram, Jamie

    2016-11-01

    Assuring sufficient quality of drinking water is of great importance for public wellbeing and prosperity. Nations have developed regulatory system with the aim of providing drinking water of sufficient quality and to minimize the risk of contamination of the water supply in the first place. In this study the chemical quality of Icelandic drinking water was evaluated by systematically analyzing results from audit monitoring where 53 parameters were assessed for 345 samples from 79 aquifers, serving 74 water supply systems. Compliance to the Icelandic Drinking Water Regulation (IDWR) was evaluated with regard to parametric values, minimum requirement of sampling, and limit of detection. Water quality compliance was divided according to health-related chemicals and indicators, and analyzed according to size. Samples from few individual locations were benchmarked against natural background levels (NBLs) in order to identify potential pollution sources. The results show that drinking compliance was 99.97% in health-related chemicals and 99.44% in indicator parameters indicating that Icelandic groundwater abstracted for drinking water supply is generally of high quality with no expected health risks. In 10 water supply systems, of the 74 tested, there was an indication of anthropogenic chemical pollution, either at the source or in the network, and in another 6 water supplies there was a need to improve the water intake to prevent surface water intrusion. Benchmarking against the NBLs proved to be useful in tracing potential pollution sources, providing a useful tool for identifying pollution at an early stage. Copyright © 2016 Elsevier GmbH. All rights reserved.

  20. Quality of groundwater resources in Afghanistan.

    PubMed

    Hayat, Ehsanullah; Baba, Alper

    2017-07-01

    Water is the main source of energy production and economy in Afghanistan where agriculture accounts for more than 50% of the country's gross domestic product (GDP). Access to safe drinking water is still a problem in the country, which has caused different health issues and even child mortality especially in rural areas. Groundwater is the main source of drinking water in the country. However, little knowledge is available about the quality of groundwater throughout the entire country, and its quality has not been investigated extensively yet like in other countries in the world. While most people think that consuming groundwater is a reliable and safe source of drinking water for health, the United Nations (UN) agencies report various kinds of waterborne diseases and even child mortalities due to drinking water quality in the country. In this article, significant geogenic and anthropogenic factors that play a vital role in groundwater contamination of the country are identified and explained. Different geogenic contaminations such as arsenic, fluoride, sulfate, and boron occur in several areas of Afghanistan that have a direct effect on human health. The water quality mapping for Afghanistan is completed for half of the country, which shows that groundwater is plagued by high levels of fluoride and arsenic in some areas. The water quality mapping of the other half of the country cannot be completed due to security concerns currently. Also, there are different kinds of waterborne diseases such as diarrhea, cholera, and dysentery that can be seen in different parts of the country because of anthropogenic activities which continuously deteriorate groundwater.

  1. Laser source with high pulse energy at 3-5 μm and 8-12 μm based on nonlinear conversion in ZnGeP2

    NASA Astrophysics Data System (ADS)

    Lippert, Espen; Fonnum, Helge; Haakestad, Magnus W.

    2014-10-01

    We present a high energy infrared laser source where a Tm:fiber laser is used to pump a high-energy 2-μm cryogenically cooled Ho:YLF laser. We have achieved 550 mJ of output energy at 2.05 μm, and through non-linear conversion in ZnGeP2 generated 200 mJ in the 3-5-μm range. Using a numerical simulation tool we have also investigated a setup which should generate more than 70 mJ in the 8-12-μm range. The conversion stage uses a master-oscillator-power-amplifier architecture to enable high conversion efficiency and good beam quality.

  2. A quality assurance device for measuring afterloader performance and transit dose for nasobiliary high-dose-rate brachytherapy.

    PubMed

    Deufel, Christopher L; Mullins, John P; Zakhary, Mark J

    2018-05-17

    Nasobiliary high-dose-rate (HDR) brachytherapy has emerged as an effective tool to boost the radiation dose for patients with unresectable perihilar cholangiocarcinoma. This work describes a quality assurance (QA) tool for measuring the HDR afterloader's performance, including the transit dose, when the source wire travels through a tortuous nasobiliary catheter path. The nasobiliary QA device was designed to mimic the anatomical path of a nasobiliary catheter, including the nasal, stomach, duodenum, and bile duct loops. Two of these loops, the duodenum and bile duct loops, have adjustable radii of curvature, resulting in the ability to maximize stress on the source wire in transit. The device was used to measure the performance over time for the HDR afterloader and the differences between intraluminal catheter lots. An upper limit on the transit dose was also measured using radiochromic film and compared with a simple theoretical model. The QA device was capable of detecting performance variations among nasobiliary catheter lots and following radioactive source replacement. The transit dose from a nasobiliary treatment increased by up to one order of magnitude when the source wire encountered higher than normal friction. Three distinct travel speeds of the source wire were observed: 5.2, 17.4, and 54.7 cm/s. The maximum transit dose was 0.3 Gy at a radial distance of 5 mm from a 40.3 kU 192 Ir source. The source wire encounters substantially greater friction when it navigates through the nasobiliary brachytherapy catheter. A QA tool that mimics the nasal, stomach, duodenum, and bile duct loops may be used to evaluate transit dose and the afterloader's performance over time. Copyright © 2018 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

  3. Contaminant point source localization error estimates as functions of data quantity and model quality

    DOE PAGES

    Hansen, Scott K.; Vesselinov, Velimir Valentinov

    2016-10-01

    We develop empirically-grounded error envelopes for localization of a point contamination release event in the saturated zone of a previously uncharacterized heterogeneous aquifer into which a number of plume-intercepting wells have been drilled. We assume that flow direction in the aquifer is known exactly and velocity is known to within a factor of two of our best guess from well observations prior to source identification. Other aquifer and source parameters must be estimated by interpretation of well breakthrough data via the advection-dispersion equation. We employ high performance computing to generate numerous random realizations of aquifer parameters and well locations, simulatemore » well breakthrough data, and then employ unsupervised machine optimization techniques to estimate the most likely spatial (or space-time) location of the source. Tabulating the accuracy of these estimates from the multiple realizations, we relate the size of 90% and 95% confidence envelopes to the data quantity (number of wells) and model quality (fidelity of ADE interpretation model to actual concentrations in a heterogeneous aquifer with channelized flow). We find that for purely spatial localization of the contaminant source, increased data quantities can make up for reduced model quality. For space-time localization, we find similar qualitative behavior, but significantly degraded spatial localization reliability and less improvement from extra data collection. Since the space-time source localization problem is much more challenging, we also tried a multiple-initial-guess optimization strategy. Furthermore, this greatly enhanced performance, but gains from additional data collection remained limited.« less

  4. Emissions of CO2 and criteria air pollutants from mobile sources: Insights from integrating real-time traffic data into local air quality models

    NASA Astrophysics Data System (ADS)

    Gately, Conor; Hutyra, Lucy

    2016-04-01

    In 2013, on-road mobile sources were responsible for over 26% of U.S. fossil fuel carbon dioxide (ffCO2) emissions, and over 34% of both CO and NOx emissions. However, accurate representations of these emissions at the scale of urban areas remains a difficult challenge. Quantifying emissions at the scale of local streets and highways is critical to provide policymakers with the information needed to develop appropriate mitigation strategies and to guide research into the underlying process that drive mobile emissions. Quantification of vehicle ffCO2 emissions at high spatial and temporal resolutions requires a detailed synthesis of data on traffic activity, roadway attributes, fleet characteristics and vehicle speeds. To accurately characterize criteria air pollutant emissions, information on local meteorology is also critical, as the temperature and relative humidity can affect emissions rates of these pollutants by as much as 400%. As the health impacts of air pollutants are more severe for residents living in close proximity (<500m) to road sources, it is critical that inventories of these emissions rely on highly resolved source data to locate potential hot-spots of exposure. In this study we utilize real-time GPS estimates of vehicle speeds to estimate ffCO2 and criteria air pollutant emissions at multiple spatial and temporal scales across a large metropolitan area. We observe large variations in emissions associated with diurnal activity patterns, congestion, sporting and civic events, and weather anomalies. We discuss the advantages and challenges of using highly-resolved source data to quantify emissions at a roadway scale, and the potential of this methodology for forecasting the air quality impacts of changes in infrastructure, urban planning policies, and regional climate.

  5. Emissions of CO2 and criteria air pollutants from mobile sources: Insights from integrating real-time traffic data into local air quality models

    NASA Astrophysics Data System (ADS)

    Gately, C.; Hutyra, L.; Sue Wing, I.; Peterson, S.; Janetos, A.

    2015-12-01

    In 2013, on-road mobile sources were responsible for over 26% of U.S. fossil fuel carbon dioxide (ffCO2) emissions, and over 34% of both CO and NOx emissions. However, accurate representations of these emissions at the scale of urban areas remains a difficult challenge. Quantifying emissions at the scale of local streets and highways is critical to provide policymakers with the information needed to develop appropriate mitigation strategies and to guide research into the underlying process that drive mobile emissions. Quantification of vehicle ffCO2 emissions at high spatial and temporal resolutions requires a detailed synthesis of data on traffic activity, roadway attributes, fleet characteristics and vehicle speeds. To accurately characterize criteria air pollutant emissions, information on local meteorology is also critical, as the temperature and relative humidity can affect emissions rates of these pollutants by as much as 400%. As the health impacts of air pollutants are more severe for residents living in close proximity (<500m) to road sources, it is critical that inventories of these emissions rely on highly resolved source data to locate potential hot-spots of exposure. In this study we utilize real-time GPS estimates of vehicle speeds to estimate ffCO2 and criteria air pollutant emissions at multiple spatial and temporal scales across a large metropolitan area. We observe large variations in emissions associated with diurnal activity patterns, congestion, sporting and civic events, and weather anomalies. We discuss the advantages and challenges of using highly-resolved source data to quantify emissions at a roadway scale, and the potential of this methodology for forecasting the air quality impacts of changes in infrastructure, urban planning policies, and regional climate.

  6. An Air Quality Data Analysis System for Interrelating Effects, Standards and Needed Source Reductions

    ERIC Educational Resources Information Center

    Larsen, Ralph I.

    1973-01-01

    Makes recommendations for a single air quality data system (using average time) for interrelating air pollution effects, air quality standards, air quality monitoring, diffusion calculations, source-reduction calculations, and emission standards. (JR)

  7. Web portal for dynamic creation and publication of teaching materials in multiple formats from a single source representation

    NASA Astrophysics Data System (ADS)

    Roganov, E. A.; Roganova, N. A.; Aleksandrov, A. I.; Ukolova, A. V.

    2017-01-01

    We implement a web portal which dynamically creates documents in more than 30 different formats including html, pdf and docx from a single original material source. It is obtained by using a number of free software such as Markdown (markup language), Pandoc (document converter), MathJax (library to display mathematical notation in web browsers), framework Ruby on Rails. The portal enables the creation of documents with a high quality visualization of mathematical formulas, is compatible with a mobile device and allows one to search documents by text or formula fragments. Moreover, it gives professors the ability to develop the latest technology educational materials, without qualified technicians' assistance, thus improving the quality of the whole educational process.

  8. Can Sanitary Inspection Surveys Predict Risk of Microbiological Contamination of Groundwater Sources? Evidence from Shallow Tubewells in Rural Bangladesh

    PubMed Central

    Ercumen, Ayse; Naser, Abu Mohd; Arnold, Benjamin F.; Unicomb, Leanne; Colford, John M.; Luby, Stephen P.

    2017-01-01

    Accurately assessing the microbiological safety of water sources is essential to reduce waterborne fecal exposures and track progress toward global targets of safe water access. Sanitary inspections are a recommended tool to assess water safety. We collected 1,684 water samples from 902 shallow tubewells in rural Bangladesh and conducted sanitary surveys to assess whether sanitary risk scores could predict water quality, as measured by Escherichia coli. We detected E. coli in 41% of tubewells, mostly at low concentrations. Based on sanitary scores, 31% of wells were low risk, 45% medium risk, and 25% high or very high risk. Older wells had higher risk scores. Escherichia coli levels were higher in wells where the platform was cracked or broken (Δlog10 = 0.09, 0.00–0.18) or undercut by erosion (Δlog10 = 0.13, 0.01–0.24). However, the positive predictive value of these risk factors for E. coli presence was low (< 50%). Latrine presence within 10 m was not associated with water quality during the wet season but was associated with less frequent E. coli detection during the dry season (relative risk = 0.72, 0.59–0.88). Sanitary scores were not associated with E. coli presence or concentration. These findings indicate that observed characteristics of a tubewell, as measured by sanitary inspections in their current form, do not sufficiently characterize microbiological water quality, as measured by E. coli. Assessments of local groundwater and geological conditions and improved water quality indicators may reveal more clear relationships. Our findings also suggest that the dominant contamination route for shallow groundwater sources is short-circuiting at the wellhead rather than subsurface transport. PMID:28115666

  9. Can Sanitary Inspection Surveys Predict Risk of Microbiological Contamination of Groundwater Sources? Evidence from Shallow Tubewells in Rural Bangladesh.

    PubMed

    Ercumen, Ayse; Naser, Abu Mohd; Arnold, Benjamin F; Unicomb, Leanne; Colford, John M; Luby, Stephen P

    2017-03-01

    AbstractAccurately assessing the microbiological safety of water sources is essential to reduce waterborne fecal exposures and track progress toward global targets of safe water access. Sanitary inspections are a recommended tool to assess water safety. We collected 1,684 water samples from 902 shallow tubewells in rural Bangladesh and conducted sanitary surveys to assess whether sanitary risk scores could predict water quality, as measured by Escherichia coli . We detected E. coli in 41% of tubewells, mostly at low concentrations. Based on sanitary scores, 31% of wells were low risk, 45% medium risk, and 25% high or very high risk. Older wells had higher risk scores. Escherichia coli levels were higher in wells where the platform was cracked or broken (Δlog 10 = 0.09, 0.00-0.18) or undercut by erosion (Δlog 10 = 0.13, 0.01-0.24). However, the positive predictive value of these risk factors for E. coli presence was low (< 50%). Latrine presence within 10 m was not associated with water quality during the wet season but was associated with less frequent E. coli detection during the dry season (relative risk = 0.72, 0.59-0.88). Sanitary scores were not associated with E. coli presence or concentration. These findings indicate that observed characteristics of a tubewell, as measured by sanitary inspections in their current form, do not sufficiently characterize microbiological water quality, as measured by E. coli . Assessments of local groundwater and geological conditions and improved water quality indicators may reveal more clear relationships. Our findings also suggest that the dominant contamination route for shallow groundwater sources is short-circuiting at the wellhead rather than subsurface transport.

  10. Spreadsheet WATERSHED modeling for nonpoint-source pollution management in a Wisconsin basin

    USGS Publications Warehouse

    Walker, J.F.; Pickard, S.A.; Sonzogni, W.C.

    1989-01-01

    Although several sophisticated nonpoint pollution models exist, few are available that are easy to use, cover a variety of conditions, and integrate a wide range of information to allow managers and planners to assess different control strategies. Here, a straightforward pollutant input accounting approach is presented in the form of an existing model (WATERSHED) that has been adapted to run on modern electronic spreadsheets. As an application, WATERSHED is used to assess options to improve the quality of highly eutrophic Delavan Lake in Wisconsin. WATERSHED is flexible in that several techniques, such as the Universal Soil Loss Equation or unit-area loadings, can be used to estimate nonpoint-source inputs. Once the model parameters are determined (and calibrated, if possible), the spreadsheet features can be used to conduct a sensitivity analysis of management options. In the case of Delavan Lake, it was concluded that, although some nonpoint controls were cost-effective, the overall reduction in phosphorus would be insufficient to measurably improve water quality.A straightforward pollutant input accounting approach is presented in the form of an existing model (WATERSHED) that has been adapted to run on modern electronic spreadsheets. As an application, WATERSHED is used to assess options to improve the quality of highly eutrophic Delavan Lake in Wisconsin. WATERSHED is flexible in that several techniques, such as the Universal Soil Loss Equation or unit-area loadings, can be used to estimate nonpoint-source inputs. Once the model parameters are determined (and calibrated, if possible), the spreadsheet features can be used to conduct a sensitivity analysis of management options. In the case of Delavan Lake, it was concluded that, although some nonpoint controls were cost-effective, the overall reduction in phosphorus would be insufficient to measurably improve water quality.

  11. Ultra-low noise supercontinuum source for ultra-high resolution optical coherence tomography at 1300 nm

    NASA Astrophysics Data System (ADS)

    Gonzalo, I. B.; Maria, M.; Engelsholm, R. D.; Feuchter, T.; Leick, L.; Moselund, P. M.; Podoleanu, A.; Bang, O.

    2018-02-01

    Supercontinuum (SC) sources are of great interest for many applications due to their ultra-broad optical bandwidth, good beam quality and high power spectral density [1]. In particular, the high average power over large bandwidths makes SC light sources excellent candidates for ultra-high resolution optical coherence tomography (UHR-OCT) [2-5]. However, conventional SC sources suffer from high pulse-to-pulse intensity fluctuations as a result of the noise-sensitive nonlinear effects involved in the SC generation process [6-9]. This intensity noise from the SC source can limit the performance of OCT, resulting in a reduced signal-to-noise ratio (SNR) [10-12]. Much work has been done to reduce the noise of the SC sources for instance with fiber tapers [7,8] or increasing the repetition rate of the pump laser for averaging in the spectrometer [10,12]. An alternative approach is to use all-normal dispersion (ANDi) fibers [13,14] to generate SC light from well-known coherent nonlinear processes [15-17]. In fact, reduction of SC noise using ANDi fibers compared to anomalous dispersion SC pumped by sub-picosecond pulses has been recently demonstrated [18], but a cladding mode was used to stabilize the ANDi SC. In this work, we characterize the noise performance of a femtosecond pumped ANDi based SC and a commercial SC source in an UHR-OCT system at 1300 nm. We show that the ANDi based SC presents exceptional noise properties compared to a commercial source. An improvement of 5 dB in SNR is measured in the UHR-OCT system, and the noise behavior resembles that of a superluminiscent diode. This preliminary study is a step forward towards development of an ultra-low noise SC source at 1300 nm for ultra-high resolution OCT.

  12. Enhanced gamma ray sensitivity in bismuth triiodide sensors through volumetric defect control

    DOE PAGES

    Johns, Paul M.; Baciak, James E.; Nino, Juan C.

    2016-09-02

    In some of the more attractive semiconducting compounds for ambient temperature radiation detector applications are impacted by low charge collection efficiency due to the presence of point and volumetric defects. This has been particularly true in the case of BiI 3, which features very attractive properties (density, atomic number, band gap, etc.) to serve as a gamma ray detector, but has yet to demonstrate its full potential. Here, we show that by applying growth techniques tailored to reduce defects, the spectral performance of this promising semiconductor can be realized. Gamma ray spectra from >100 keV source emissions are now obtainedmore » from high quality Sb:BiI 3 bulk crystals with limited concentrations of defects (point and extended). The spectra acquired in these high quality crystals feature photopeaks with resolution of 2.2% at 662 keV. Infrared microscopy is used to compare the local microstructure between radiation sensitive and non-responsive crystals. Our work demonstrates that BiI 3 can be prepared in melt-grown detector-grade samples with superior quality and can acquire the spectra from a variety of gamma ray sources.« less

  13. Chalcogenide based rib waveguide for compact on-chip supercontinuum sources in mid-infrared domain

    NASA Astrophysics Data System (ADS)

    Saini, Than Singh; Tiwari, Umesh Kumar; Sinha, Ravindra Kumar

    2017-08-01

    We have designed and analysed a rib waveguide structure in recently reported Ga-Sb-S based highly nonlinear chalcogenide glass for nonlinear applications. The proposed waveguide structure possesses a very high nonlinear coefficient and can be used to generate broadband supercontinuum in mid-infrared domain. The reported design of the chalcogenide waveguide offers two zero dispersion values at 1800 nm and 2900 nm. Such rib waveguide structure is suitable to generate efficient supercontinuum generation ranging from 500 - 7400 μm. The reported waveguide can be used for the realization of the compact on-chip supercontinuum sources which are highly applicable in optical imaging, optical coherence tomography, food quality control, security and sensing.

  14. Description and Yield of Current Quality and Safety Review in Selected US Academic Emergency Departments.

    PubMed

    Griffey, Richard Thomas; Schneider, Ryan M; Sharp, Brian R; Pothof, Jeffrey J; Hodkins, Sheridan; Capp, Roberta; Wiler, Jennifer L; Sreshta, Neil; Sather, John E; Sampson, Christopher S; Powell, Jonathan T; Groner, Kathryn Y; Adler, Lee M

    2017-06-29

    Quality and safety review for performance improvement is important for systems of care and is required for US academic emergency departments (EDs). Assessment of the impact of patient safety initiatives in the context of increasing burdens of quality measurement compels standardized, meaningful, high-yield approaches for performance review. Limited data describe how quality and safety reviews are currently conducted and how well they perform in detecting patient harm and areas for improvement. We hypothesized that decades-old approaches used in many academic EDs are inefficient and low yield for identifying patient harm. We conducted a prospective observational study to evaluate the efficiency and yield of current quality review processes at five academic EDs for a 12-month period. Sites provided descriptions of their current practice and collected summary data on the number and severity of events identified in their reviews and the referral sources that led to their capture. Categories of common referral sources were established at the beginning of the study. Sites used the Institute for Healthcare Improvement's definition in defining an adverse event and a modified National Coordinating Council for Medication Error Reporting and Prevention (MERP) Index for grading severity of events. Participating sites had similar processes for quality review, including a two-level review process, monthly reviews and conferences, similar screening criteria, and a grading system for evaluating cases. In 60 months of data collection, we reviewed a total of 4735 cases and identified 381 events. This included 287 near-misses, errors/events (MERP A-I) and 94 adverse events (AEs) (MERP E-I). The overall AE rate (event rate with harm) was 1.99 (95% confidence interval = 1.62%-2.43%), ranging from 1.24% to 3.47% across sites. The overall rate of quality concerns (events without harm) was 6.06% (5.42%-6.78%), ranging from 2.96% to 10.95% across sites. Seventy-two-hour returns were the most frequent referral source used, accounting for 47% of the cases reviewed but with a yield of only 0.81% in identifying harm. Other referral sources similarly had very low yields. External referrals were the highest yield referral source, with 14.34% (10.64%-19.03%) identifying AEs. As a percentage of the 94 AEs identified, external referrals also accounted for 41.49% of cases. With an overall adverse event rate of 1.99%, commonly used referral sources seem to be low yield and inefficient for detecting patient harm. Approximately 6% of the cases identified by these criteria yielded a near miss or quality concern. New approaches to quality and safety review in the ED are needed to optimize their yield and efficiency for identifying harm and areas for improvement.

  15. Human collagen produced in plants: more than just another molecule.

    PubMed

    Shoseyov, Oded; Posen, Yehudit; Grynspan, Frida

    2014-01-01

    Consequential to its essential role as a mechanical support and affinity regulator in extracellular matrices, collagen constitutes a highly sought after scaffolding material for regeneration and healing applications. However, substantiated concerns have been raised with regard to quality and safety of animal tissue-extracted collagen, particularly in relation to its immunogenicity, risk of disease transmission and overall quality and consistency. In parallel, contamination with undesirable cellular factors can significantly impair its bioactivity, vis-a-vis its impact on cell recruitment, proliferation and differentiation. High-scale production of recombinant human collagen Type I (rhCOL1) in the tobacco plant provides a source of an homogenic, heterotrimeric, thermally stable "virgin" collagen which self assembles to fine homogenous fibrils displaying intact binding sites and has been applied to form numerous functional scaffolds for tissue engineering and regenerative medicine. In addition, rhCOL1 can form liquid crystal structures, yielding a well-organized and mechanically strong membrane, two properties indispensable to extracellular matrix (ECM) mimicry. Overall, the shortcomings of animal- and cadaver-derived collagens arising from their source diversity and recycled nature are fully overcome in the plant setting, constituting a collagen source ideal for tissue engineering and regenerative medicine applications.

  16. Web-based decision support and visualization tools for water quality management in the Chesapeake Bay watershed

    USGS Publications Warehouse

    Mullinix, C.; Hearn, P.; Zhang, H.; Aguinaldo, J.

    2009-01-01

    Federal, State, and local water quality managers charged with restoring the Chesapeake Bay ecosystem require tools to maximize the impact of their limited resources. To address this need, the U.S. Geological Survey (USGS) and the Environmental Protection Agency's Chesapeake Bay Program (CBP) are developing a suite of Web-based tools called the Chesapeake Online Assessment Support Toolkit (COAST). The goal of COAST is to help CBP partners identify geographic areas where restoration activities would have the greatest effect, select the appropriate management strategies, and improve coordination and prioritization among partners. As part of the COAST suite of tools focused on environmental restoration, a water quality management visualization component called the Nutrient Yields Mapper (NYM) tool is being developed by USGS. The NYM tool is a web application that uses watershed yield estimates from USGS SPAtially Referenced Regressions On Watershed (SPARROW) attributes model (Schwarz et al., 2006) [6] to allow water quality managers to identify important sources of nitrogen and phosphorous within the Chesapeake Bay watershed. The NYM tool utilizes new open source technologies that have become popular in geospatial web development, including components such as OpenLayers and GeoServer. This paper presents examples of water quality data analysis based on nutrient type, source, yield, and area of interest using the NYM tool for the Chesapeake Bay watershed. In addition, we describe examples of map-based techniques for identifying high and low nutrient yield areas; web map engines; and data visualization and data management techniques.

  17. Assessment of physico-chemical quality of borehole and spring water sources supplied to Robe Town, Oromia region, Ethiopia

    NASA Astrophysics Data System (ADS)

    Shigut, Dagim Abera; Liknew, Geremew; Irge, Dejene Disasa; Ahmad, Tanweer

    2017-03-01

    The study was carried out to find the physico-chemical water quality of borehole and spring water supplied to Robe Town. For this study, a total of six water samples were collected from three borehole and three spring water sources. The analyses for 14 physico-chemical parameters, pH, turbidity, electrical conductivity, total dissolved solids, total suspended solids total hardness cations (Ca2+, Mg2+), anions (NO2 -, NO3 -, SO4 2- and PO4 3-) and heavy metals (Fe and Mn), were done in the laboratory by adopting standard procedures suggested by the American Public Health Association (APHA). Descriptive statistics were used to describe data, while Pearson correlation was used to determine the influences of the physico-chemical variables. The single factor analysis of variance ( t test) was used to determine possible differences between the borehole and spring water, while means plots were used for further structure detection. From the total samples analyzed, most of the samples comply with the water quality guidelines of Ethiopian limit, WHO and U.SEPA. The pH of the water samples from borehole groundwater source was found to be slightly acidic and bove the maximum permissible limit (MPL). High concentration of Fe and Mn that exceeds the MPL set by WHO was found in the three boreholes. The spring water sources were found to be better for drinking than borehole water sources.

  18. Volume 2 - Point Sources

    EPA Pesticide Factsheets

    Point source emission reference materials from the Emissions Inventory Improvement Program (EIIP). Provides point source guidance on planning, emissions estimation, data collection, inventory documentation and reporting, and quality assurance/quality contr

  19. Source Water Quality Monitoring

    EPA Science Inventory

    Presentation will provide background information on continuous source water monitoring using online toxicity monitors and cover various tools available. Conceptual and practical aspects of source water quality monitoring will be discussed.

  20. MANGROVE-EXPORTED NUTRIENT INCORPORATION BY SESSILE CORAL REEF INVERTEBRATES

    EPA Science Inventory

    Coastal mangrove forests were historically considered as a source of organic matter (OM) for adjacent marine systems due to high net primary production; yet recent research suggesting little uptake through the food web because of low nutritional quality, challenges the concept of...

  1. Cellular-enabled water quality measurements

    NASA Astrophysics Data System (ADS)

    Zhao, Y.; Kerkez, B.

    2013-12-01

    While the past decade has seen significant improvements in our ability to measure nutrients and other water quality parameters, the use of these sensors has yet to gain traction due to their costprohibitive nature and deployment expertise required on the part of researchers. Furthermore, an extra burden is incurred when real-time data access becomes an experimental requirement. We present an open-source hardware design to facilitate the real-time, low-cost, and robust measurements of water quality across large urbanized areas. Our hardware platform interfaces an embedded, vastly configurable, high-precision, ultra-low power measurement system, with a low-power cellular module. Each sensor station is configured with an IP address, permitting reliable streaming of sensor data to off-site locations as measurements are made. We discuss the role of high-quality hardware components during extreme event scenarios, and present preliminary performance metrics that validate the ability of the platform to provide streaming access to sensor measurements.

  2. Effects of irrigating with wastewater on ground-water quality at Fort Carson Military Reservation golf course near Colorado Springs, Colorado

    USGS Publications Warehouse

    Edelmann, Patrick

    1984-01-01

    Fort Carson Military Reservation has used treatment wastewater for irrigation of the Fort Carson golf course since 1971. The effect of applied wastewater on groundwater quality at Fort Carson golf course was evaluated using water levels and water-quality data from 20 observation wells. The water-quality constituents analyzed included dissolved solids, major ions, nutrients, detergents, dissolved organic carbon, chemical and biological oxygen demand, and trace elements. Effects of the applied wastewater on ground-water quality for most constituents were obscured by large areal variations and by high concentrations of the constituents upgradient from the golf course. The sources of nitrogen observed in the ground water beneath the golf course were applied wastewater, applied fertilizer, leachate from the organic-rich shale, and from unknown upgradient sources. Nitrogen loading at the golf course from wastewater and applied fertilizer was estimated to be 18 ,900 pounds per year. After 10 years, less than 1 percent of the nitrogen applied was actually present in the ground water. Loss of nitrogen to the atmosphere as nitrous oxides, absorption, and to fixation by grass resulted in the much smaller concentrations observed in the ground water. (USGS)

  3. Effectiveness of SWAT in characterizing the watershed hydrology in the snowy-mountainous Lower Bear Malad River (LBMR) watershed in Box Elder County, Utah

    NASA Astrophysics Data System (ADS)

    Salha, A. A.; Stevens, D. K.

    2015-12-01

    Distributed watershed models are essential for quantifying sediment and nutrient loads that originate from point and nonpoint sources. Such models are primary means towards generating pollutant estimates in ungaged watersheds and respond well at watershed scales by capturing the variability in soils, climatic conditions, land uses/covers and management conditions over extended periods of time. This effort evaluates the performance of the Soil and Water Assessment Tool (SWAT) model as a watershed level tool to investigate, manage, and characterize the transport and fate of nutrients in Lower Bear Malad River (LBMR) watershed (Subbasin HUC 16010204) in Utah. Water quality concerns have been documented and are primarily attributed to high phosphorus and total suspended sediment concentrations caused by agricultural and farming practices along with identified point sources (WWTPs). Input data such as Digital Elevation Model (DEM), land use/Land cover (LULC), soils, and climate data for 10 years (2000-2010) is utilized to quantify the LBMR streamflow. Such modeling is useful in developing the required water quality regulations such as Total Maximum Daily Loads (TMDL). Measured concentrations of nutrients were closely captured by simulated monthly nutrient concentrations based on the R2 and Nash- Sutcliffe fitness criteria. The model is expected to be able to identify contaminant non-point sources, identify areas of high pollution risk, locate optimal monitoring sites, and evaluate best management practices to cost-effectively reduce pollution and improve water quality as required by the LBMR watershed's TMDL.

  4. Grandmothers Raising Grandchildren with Disabilities: Sources of Support and Family Quality of Life

    ERIC Educational Resources Information Center

    Kresak, Karen E.; Gallagher, Peggy A.; Kelley, Susan J.

    2014-01-01

    Sources of support and quality of life of 50 grandmother-headed families raising grandchildren with and without disabilities were examined. Comparative analyses revealed significant differences between grandmothers raising grandchildren with and without disabilities in regard to sources of support and family quality of life. Informal support was…

  5. Water Source Pollution and Disease Diagnosis in a Nigerian Rural Community.

    ERIC Educational Resources Information Center

    Sangodoyin, A. Y.

    1991-01-01

    Samples from five water sources (spring, borehole, pond, stream, and well) in rural Nigerian communities were tested. Results include source reliabilities in terms of water quality and quantity, pollution effects upon water quality, epidemiological effects related to water quantity and waste disposal, and impact of water quality improvement upon…

  6. Free-breathing high-pitch 80kVp dual-source computed tomography of the pediatric chest: Image quality, presence of motion artifacts and radiation dose.

    PubMed

    Bodelle, Boris; Fischbach, Constanze; Booz, Christian; Yel, Ibrahim; Frellesen, Claudia; Beeres, Martin; Vogl, Thomas J; Scholtz, Jan-Erik

    2017-04-01

    To investigate image quality, presence of motion artifacts and effects on radiation dose of 80kVp high-pitch dual-source CT (DSCT) in combination with an advanced modeled iterative reconstruction algorithm (ADMIRE) of the pediatric chest compared to single-source CT (SSCT). The study was approved by the institutional review board. Eighty-seven consecutive pediatric patients (mean age 9.1±4.9years) received either free-breathing high-pitch (pitch 3.2) chest 192-slice DSCT (group 1, n=31) or standard-pitch (pitch 1.2) 128-slice SSCT (group 2, n=56) with breathing-instructions by random assignment. Tube settings were similar in both groups with 80 kVp and 74 ref. mAs. Images were reconstructed using FBP for both groups. Additionally, ADMIRE was used in group 1. Effective thorax diameter, image noise, and signal-to-noise ratio (SNR) of the pectoralis major muscle and the thoracic aorta were calculated. Motion artifacts were measured as doubling boarders of the diaphragm and the heart. Images were rated by two blinded readers for overall image quality and presence of motion artifacts on 5-point-scales. Size specific dose estimates (SSDE, mGy) and effective dose (ED, mSv) were calculated. Age and effective thorax diameter showed no statistically significant differences in both groups. Image noise and SNR were comparable (p>0.64) for SSCT and DSCT with ADMIRE, while DSCT with FBP showed inferior results (p<0.01). Motion artifacts were reduced significantly (p=0.001) with DSCT. DSCT with ADMIRE showed the highest overall IQ (p<0.0001). Radiation dose was lower for DSCT compared to SSCT (median SSDE: 0.82mGy vs. 0.92mGy, p<0.02; median ED: 0.4 mSv vs. 0.48mSv, p=0.02). High-pitch 80kVp chest DSCT in combination with ADMIRE reduces motion artifacts and increases image quality while lowering radiation exposure in free-breathing pediatric patients without sedation. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. Air Quality from Early Pittsburgh to the Present: The Science of Change

    NASA Astrophysics Data System (ADS)

    Davidson, Cliff

    2009-03-01

    Throughout Pittsburgh's history over the past 250 years, coal reserves in the city and nearby have influenced its economy, demographics, and environmental quality. They have also played a major role in determining air quality in the region. For example, Pittsburgh became famous for its high particle loadings as early as the beginning of the nineteenth century, when the first complaints about air quality in the city were recorded. Nevertheless, residents tolerated the high coal smoke levels since jobs depended on the iron works, steel mills, and other industries. When natural gas was discovered just east of the city in the 1870's and replaced coal for some applications, particle concentrations decreased. But the local supplies of natural gas ran short several years later, and as industry continued to expand in the 1890's the city went back to the use of coal as its primary fuel. The return to smoky air was met with resistance that marked the beginning of sustained public outcry and initiation of several air pollution studies. The next half century was marked by periods of occasional high and low concentration, the latter due to events such as the financial panic of 1907 and the depression of the 1930's. It was not until the 1940's that effective regulations were passed to reduce smoky conditions. Particle levels fell throughout the 1950's and 1960's, and eventually the decline of heavy industry in Pittsburgh led to relatively clean air in many parts of the city. Over the past few decades, airborne particle concentrations averaged across the Pittsburgh region have remained below their earlier levels. However, there are still ``hot spots'' of high concentration resulting from regional background coming from upwind areas and emissions of some large sources that have continued to operate in the Pittsburgh region. Furthermore, the composition of airborne particles in the city has changed from earlier times. Such particles are now the result of emissions from sources in upwind states, greater numbers of mobile sources, and the influence of control technologies that remove certain classes of pollutants but not others.

  8. Geophysical insights on the GIA process provided by high-quality constraints from peripheral regions: An outlook on perspectives from North America and from the Mediterranean basin

    NASA Astrophysics Data System (ADS)

    Roy, K.; Peltier, W. R.

    2017-12-01

    Our understanding of the Earth-Ice-Ocean interactions that have accompanied the large glaciation-deglaciation process characteristic of the last half of the Pleistocene has benefited significantly from the development of high-quality models of the Glacial Isostatic Adjustment (GIA) process. These models provide fundamental insight on the large changes in sea level and land ice cover over this time period, as well as key constraints on the viscosity structure of the Earth's interior. Their development has benefited from the recent availability of high-quality constraints from regions of forebulge collapse. In particular, over North America, the joint use of high-quality sea level data from the U.S. East coast, together with the vast network of precise space-geodetic observations of crustal motion existing over most of the interior of the continent, has led to the latest ICE-7G_NA (VM7) model (Roy & Peltier, GJI, 2017). In this paper, exciting opportunities provided by such high-quality observations related to the GIA process will be discussed, not only in the context of the continuing effort to refine global models of this phenomenon, but also in terms of the fundamental insight they may provide on outstanding issues in high-pressure geophysics, paleoclimatology or hydrogeology. Specific examples where such high-quality observations can be used (either separately, or using a combination of independent sources) will be presented, focusing particularly on constraints from the North American continent and from the Mediterranean basin. This work will demonstrate that, given the high-quality of currently available constraints on the GIA process, considerable further geophysical insight can be obtained based upon the use of spherically-symmetric models of the viscosity structure of the planet.

  9. High-resolution μCT of a mouse embryo using a compact laser-driven X-ray betatron source.

    PubMed

    Cole, Jason M; Symes, Daniel R; Lopes, Nelson C; Wood, Jonathan C; Poder, Kristjan; Alatabi, Saleh; Botchway, Stanley W; Foster, Peta S; Gratton, Sarah; Johnson, Sara; Kamperidis, Christos; Kononenko, Olena; De Lazzari, Michael; Palmer, Charlotte A J; Rusby, Dean; Sanderson, Jeremy; Sandholzer, Michael; Sarri, Gianluca; Szoke-Kovacs, Zsombor; Teboul, Lydia; Thompson, James M; Warwick, Jonathan R; Westerberg, Henrik; Hill, Mark A; Norris, Dominic P; Mangles, Stuart P D; Najmudin, Zulfikar

    2018-06-19

    In the field of X-ray microcomputed tomography (μCT) there is a growing need to reduce acquisition times at high spatial resolution (approximate micrometers) to facilitate in vivo and high-throughput operations. The state of the art represented by synchrotron light sources is not practical for certain applications, and therefore the development of high-brightness laboratory-scale sources is crucial. We present here imaging of a fixed embryonic mouse sample using a compact laser-plasma-based X-ray light source and compare the results to images obtained using a commercial X-ray μCT scanner. The radiation is generated by the betatron motion of electrons inside a dilute and transient plasma, which circumvents the flux limitations imposed by the solid or liquid anodes used in conventional electron-impact X-ray tubes. This X-ray source is pulsed (duration <30 fs), bright (>10 10 photons per pulse), small (diameter <1 μm), and has a critical energy >15 keV. Stable X-ray performance enabled tomographic imaging of equivalent quality to that of the μCT scanner, an important confirmation of the suitability of the laser-driven source for applications. The X-ray flux achievable with this approach scales with the laser repetition rate without compromising the source size, which will allow the recording of high-resolution μCT scans in minutes. Copyright © 2018 the Author(s). Published by PNAS.

  10. Interventions to improve water quality for preventing diarrhoea.

    PubMed

    Clasen, Thomas F; Alexander, Kelly T; Sinclair, David; Boisson, Sophie; Peletz, Rachel; Chang, Howard H; Majorin, Fiona; Cairncross, Sandy

    2015-10-20

    Diarrhoea is a major cause of death and disease, especially among young children in low-income countries. In these settings, many infectious agents associated with diarrhoea are spread through water contaminated with faeces.In remote and low-income settings, source-based water quality improvement includes providing protected groundwater (springs, wells, and bore holes), or harvested rainwater as an alternative to surface sources (rivers and lakes). Point-of-use water quality improvement interventions include boiling, chlorination, flocculation, filtration, or solar disinfection, mainly conducted at home. To assess the effectiveness of interventions to improve water quality for preventing diarrhoea. We searched the Cochrane Infectious Diseases Group Specialized Register (11 November 2014), CENTRAL (the Cochrane Library, 7 November 2014), MEDLINE (1966 to 10 November 2014), EMBASE (1974 to 10 November 2014), and LILACS (1982 to 7 November 2014). We also handsearched relevant conference proceedings, contacted researchers and organizations working in the field, and checked references from identified studies through 11 November 2014. Randomized controlled trials (RCTs), quasi-RCTs, and controlled before-and-after studies (CBA) comparing interventions aimed at improving the microbiological quality of drinking water with no intervention in children and adults. Two review authors independently assessed trial quality and extracted data. We used meta-analyses to estimate pooled measures of effect, where appropriate, and investigated potential sources of heterogeneity using subgroup analyses. We assessed the quality of evidence using the GRADE approach. Forty-five cluster-RCTs, two quasi-RCTs, and eight CBA studies, including over 84,000 participants, met the inclusion criteria. Most included studies were conducted in low- or middle-income countries (LMICs) (50 studies) with unimproved water sources (30 studies) and unimproved or unclear sanitation (34 studies). The primary outcome in most studies was self-reported diarrhoea, which is at high risk of bias due to the lack of blinding in over 80% of the included studies. Source-based water quality improvementsThere is currently insufficient evidence to know if source-based improvements such as protected wells, communal tap stands, or chlorination/filtration of community sources consistently reduce diarrhoea (one cluster-RCT, five CBA studies, very low quality evidence). We found no studies evaluating reliable piped-in water supplies delivered to households. Point-of-use water quality interventionsOn average, distributing water disinfection products for use at the household level may reduce diarrhoea by around one quarter (Home chlorination products: RR 0.77, 95% CI 0.65 to 0.91; 14 trials, 30,746 participants, low quality evidence; flocculation and disinfection sachets: RR 0.69, 95% CI 0.58 to 0.82, four trials, 11,788 participants, moderate quality evidence). However, there was substantial heterogeneity in the size of the effect estimates between individual studies.Point-of-use filtration systems probably reduce diarrhoea by around a half (RR 0.48, 95% CI 0.38 to 0.59, 18 trials, 15,582 participants, moderate quality evidence). Important reductions in diarrhoea episodes were shown with ceramic filters, biosand systems and LifeStraw® filters; (Ceramic: RR 0.39, 95% CI 0.28 to 0.53; eight trials, 5763 participants, moderate quality evidence; Biosand: RR 0.47, 95% CI 0.39 to 0.57; four trials, 5504 participants, moderate quality evidence; LifeStraw®: RR 0.69, 95% CI 0.51 to 0.93; three trials, 3259 participants, low quality evidence). Plumbed in filters have only been evaluated in high-income settings (RR 0.81, 95% CI 0.71 to 0.94, three trials, 1056 participants, fixed effects model).In low-income settings, solar water disinfection (SODIS) by distribution of plastic bottles with instructions to leave filled bottles in direct sunlight for at least six hours before drinking probably reduces diarrhoea by around a third (RR 0.62, 95% CI 0.42 to 0.94; four trials, 3460 participants, moderate quality evidence).In subgroup analyses, larger effects were seen in trials with higher adherence, and trials that provided a safe storage container. In most cases, the reduction in diarrhoea shown in the studies was evident in settings with improved and unimproved water sources and sanitation. Interventions that address the microbial contamination of water at the point-of-use may be important interim measures to improve drinking water quality until homes can be reached with safe, reliable, piped-in water connections. The average estimates of effect for each individual point-of-use intervention generally show important effects. Comparisons between these estimates do not provide evidence of superiority of one intervention over another, as such comparisons are confounded by the study setting, design, and population.Further studies assessing the effects of household connections and chlorination at the point of delivery will help improve our knowledge base. As evidence suggests effectiveness improves with adherence, studies assessing programmatic approaches to optimising coverage and long-term utilization of these interventions among vulnerable populations could also help strategies to improve health outcomes.

  11. Seasonal assessment and apportionment of surface water pollution using multivariate statistical methods: Sinos River, southern Brazil.

    PubMed

    Alves, Darlan Daniel; Riegel, Roberta Plangg; de Quevedo, Daniela Müller; Osório, Daniela Montanari Migliavacca; da Costa, Gustavo Marques; do Nascimento, Carlos Augusto; Telöken, Franko

    2018-06-08

    Assessment of surface water quality is an issue of currently high importance, especially in polluted rivers which provide water for treatment and distribution as drinking water, as is the case of the Sinos River, southern Brazil. Multivariate statistical techniques allow a better understanding of the seasonal variations in water quality, as well as the source identification and source apportionment of water pollution. In this study, the multivariate statistical techniques of cluster analysis (CA), principal component analysis (PCA), and positive matrix factorization (PMF) were used, along with the Kruskal-Wallis test and Spearman's correlation analysis in order to interpret a water quality data set resulting from a monitoring program conducted over a period of almost two years (May 2013 to April 2015). The water samples were collected from the raw water inlet of the municipal water treatment plant (WTP) operated by the Water and Sewage Services of Novo Hamburgo (COMUSA). CA allowed the data to be grouped into three periods (autumn and summer (AUT-SUM); winter (WIN); spring (SPR)). Through the PCA, it was possible to identify that the most important parameters in contribution to water quality variations are total coliforms (TCOLI) in SUM-AUT, water level (WL), water temperature (WT), and electrical conductivity (EC) in WIN and color (COLOR) and turbidity (TURB) in SPR. PMF was applied to the complete data set and enabled the source apportionment water pollution through three factors, which are related to anthropogenic sources, such as the discharge of domestic sewage (mostly represented by Escherichia coli (ECOLI)), industrial wastewaters, and agriculture runoff. The results provided by this study demonstrate the contribution provided by the use of integrated statistical techniques in the interpretation and understanding of large data sets of water quality, showing also that this approach can be used as an efficient methodology to optimize indicators for water quality assessment.

  12. DOE Office of Scientific and Technical Information (OSTI.GOV)

    McMillan, Kyle; Marleau, Peter; Brubaker, Erik

    In coded aperture imaging, one of the most important factors determining the quality of reconstructed images is the choice of mask/aperture pattern. In many applications, uniformly redundant arrays (URAs) are widely accepted as the optimal mask pattern. Under ideal conditions, thin and highly opaque masks, URA patterns are mathematically constructed to provide artifact-free reconstruction however, the number of URAs for a chosen number of mask elements is limited and when highly penetrating particles such as fast neutrons and high-energy gamma-rays are being imaged, the optimum is seldom achieved. In this case more robust mask patterns that provide better reconstructed imagemore » quality may exist. Through the use of heuristic optimization methods and maximum likelihood expectation maximization (MLEM) image reconstruction, we show that for both point and extended neutron sources a random mask pattern can be optimized to provide better image quality than that of a URA.« less

  13. Facile fabrication of high-quality Ag/PS coaxial nanocables based on the mixed mode of soft/hard templates

    NASA Astrophysics Data System (ADS)

    Wan, Mimi; Zhao, Wenbo; Peng, Fang; Wang, Qi; Xu, Ping; Mao, Chun; Shen, Jian

    2016-08-01

    A new kind of high-quality Ag/PS coaxial nanocables can be facilely synthesized by using soft/hard templates method. In order to effectively introduce Ag sources into porous polystyrene (PS) nanotubes which were trapped in porous anodic aluminum oxide (AAO) hard template, Pluronic F127 (F127) was used as guiding agent, soft template and reductant. Meanwhile, ethylene glycol solution was also used as solvent and co-reducing agent to assist in the formation of silver nanowires. The influences of concentration of F127 and reducing reaction time on the formation of Ag/PS coaxial nanocables were discussed. Results indicated that the high-quality Ag/PS coaxial nanocables can be obtained by the mixed mode of soft/hard templates under optimized conditions. This strategy is expected to be extended to design more metal/polymer coaxial nanocables for the benefit of creation of complex and functional nanoarchitectures and components.

  14. True Randomness from Big Data.

    PubMed

    Papakonstantinou, Periklis A; Woodruff, David P; Yang, Guang

    2016-09-26

    Generating random bits is a difficult task, which is important for physical systems simulation, cryptography, and many applications that rely on high-quality random bits. Our contribution is to show how to generate provably random bits from uncertain events whose outcomes are routinely recorded in the form of massive data sets. These include scientific data sets, such as in astronomics, genomics, as well as data produced by individuals, such as internet search logs, sensor networks, and social network feeds. We view the generation of such data as the sampling process from a big source, which is a random variable of size at least a few gigabytes. Our view initiates the study of big sources in the randomness extraction literature. Previous approaches for big sources rely on statistical assumptions about the samples. We introduce a general method that provably extracts almost-uniform random bits from big sources and extensively validate it empirically on real data sets. The experimental findings indicate that our method is efficient enough to handle large enough sources, while previous extractor constructions are not efficient enough to be practical. Quality-wise, our method at least matches quantum randomness expanders and classical world empirical extractors as measured by standardized tests.

  15. True Randomness from Big Data

    NASA Astrophysics Data System (ADS)

    Papakonstantinou, Periklis A.; Woodruff, David P.; Yang, Guang

    2016-09-01

    Generating random bits is a difficult task, which is important for physical systems simulation, cryptography, and many applications that rely on high-quality random bits. Our contribution is to show how to generate provably random bits from uncertain events whose outcomes are routinely recorded in the form of massive data sets. These include scientific data sets, such as in astronomics, genomics, as well as data produced by individuals, such as internet search logs, sensor networks, and social network feeds. We view the generation of such data as the sampling process from a big source, which is a random variable of size at least a few gigabytes. Our view initiates the study of big sources in the randomness extraction literature. Previous approaches for big sources rely on statistical assumptions about the samples. We introduce a general method that provably extracts almost-uniform random bits from big sources and extensively validate it empirically on real data sets. The experimental findings indicate that our method is efficient enough to handle large enough sources, while previous extractor constructions are not efficient enough to be practical. Quality-wise, our method at least matches quantum randomness expanders and classical world empirical extractors as measured by standardized tests.

  16. True Randomness from Big Data

    PubMed Central

    Papakonstantinou, Periklis A.; Woodruff, David P.; Yang, Guang

    2016-01-01

    Generating random bits is a difficult task, which is important for physical systems simulation, cryptography, and many applications that rely on high-quality random bits. Our contribution is to show how to generate provably random bits from uncertain events whose outcomes are routinely recorded in the form of massive data sets. These include scientific data sets, such as in astronomics, genomics, as well as data produced by individuals, such as internet search logs, sensor networks, and social network feeds. We view the generation of such data as the sampling process from a big source, which is a random variable of size at least a few gigabytes. Our view initiates the study of big sources in the randomness extraction literature. Previous approaches for big sources rely on statistical assumptions about the samples. We introduce a general method that provably extracts almost-uniform random bits from big sources and extensively validate it empirically on real data sets. The experimental findings indicate that our method is efficient enough to handle large enough sources, while previous extractor constructions are not efficient enough to be practical. Quality-wise, our method at least matches quantum randomness expanders and classical world empirical extractors as measured by standardized tests. PMID:27666514

  17. III-V quantum light source and cavity-QED on silicon.

    PubMed

    Luxmoore, I J; Toro, R; Del Pozo-Zamudio, O; Wasley, N A; Chekhovich, E A; Sanchez, A M; Beanland, R; Fox, A M; Skolnick, M S; Liu, H Y; Tartakovskii, A I

    2013-01-01

    Non-classical light sources offer a myriad of possibilities in both fundamental science and commercial applications. Single photons are the most robust carriers of quantum information and can be exploited for linear optics quantum information processing. Scale-up requires miniaturisation of the waveguide circuit and multiple single photon sources. Silicon photonics, driven by the incentive of optical interconnects is a highly promising platform for the passive optical components, but integrated light sources are limited by silicon's indirect band-gap. III-V semiconductor quantum-dots, on the other hand, are proven quantum emitters. Here we demonstrate single-photon emission from quantum-dots coupled to photonic crystal nanocavities fabricated from III-V material grown directly on silicon substrates. The high quality of the III-V material and photonic structures is emphasized by observation of the strong-coupling regime. This work opens-up the advantages of silicon photonics to the integration and scale-up of solid-state quantum optical systems.

  18. The Challenges of Data Quality Evaluation in a Joint Data Warehouse

    PubMed Central

    Bae, Charles J.; Griffith, Sandra; Fan, Youran; Dunphy, Cheryl; Thompson, Nicolas; Urchek, John; Parchman, Alandra; Katzan, Irene L.

    2015-01-01

    Introduction: The use of clinically derived data from electronic health records (EHRs) and other electronic clinical systems can greatly facilitate clinical research as well as operational and quality initiatives. One approach for making these data available is to incorporate data from different sources into a joint data warehouse. When using such a data warehouse, it is important to understand the quality of the data. The primary objective of this study was to determine the completeness and concordance of common types of clinical data available in the Knowledge Program (KP) joint data warehouse, which contains feeds from several electronic systems including the EHR. Methods: A manual review was performed of specific data elements for 250 patients from an EHR, and these were compared with corresponding elements in the KP data warehouse. Completeness and concordance were calculated for five categories of data including demographics, vital signs, laboratory results, diagnoses, and medications. Results: In general, data elements for demographics, vital signs, diagnoses, and laboratory results were present in more cases in the source EHR compared to the KP. When data elements were available in both sources, there was a high concordance. In contrast, the KP data warehouse documented a higher prevalence of deaths and medications compared to the EHR. Discussion: Several factors contributed to the discrepancies between data in the KP and the EHR—including the start date and frequency of data feeds updates into the KP, inability to transfer data located in nonstructured formats (e.g., free text or scanned documents), as well as incomplete and missing data variables in the source EHR. Conclusion: When evaluating the quality of a data warehouse with multiple data sources, assessing completeness and concordance between data set and source data may be better than designating one to be a gold standard. This will allow the user to optimize the method and timing of data transfer in order to capture data with better accuracy. PMID:26290882

  19. A Survey of Information Source Preferences of Parents of Individuals with Autism Spectrum Disorder.

    PubMed

    Gibson, Amelia N; Kaplan, Samantha; Vardell, Emily

    2017-07-01

    For parents of children with an Autism spectrum disorder (ASD), high quality, easily accessible information and a strong peer network can be the key to raising a happy, healthy child, and maintaining family well-being and emotional resilience. This article reports the findings of an anonymous survey examining the information source preferences for 935 parents of individuals with ASDs in North Carolina. Data indicates that parents show similar information seeking patterns across the age spectrum, that availability of information (as indicated by overall information source selection) decrease as children age. It also shows that parents rely heavily on local sources of information, preferring them to nonlocal sources (such as the internet) for many types of information.

  20. Improving chocolate flavor in poor-quality cocoa almonds by enzymatic treatment.

    PubMed

    Oliveira, Hilana Salete Silva; Mamede, Maria Eugênia Oliveira; Góes-Neto, Aristóteles; Koblitz, Maria Gabriela Bello

    2011-01-01

    This paper proposes a method to enzymatically treat poor-quality cocoa almonds (known as "slate") to ensure the formation of chocolate flavor precursors. The production of flavor precursors improves the quality of these almonds, which are usually responsible for the low quality of the liquor produced. Proteases and carboxypeptidases from different sources were tested under various conditions. The different treatments were evaluated by chemical analysis (hydrolysis efficiency) and sensory analysis of the treated material compared to good-quality cocoa almonds. The results show that it is possible, through the use of microbial enzymes, to generate the mixture of compounds that will release, after roasting, the characteristic chocolate flavor in poor-quality almonds. However, it is necessary to optimize the conditions of enzymatic treatment to obtain better results and thus establish a process that can be used for industrial purposes for manufacturing cocoa and chocolate. The basidiomycete Moniliophtora perniciosa is the causative agent of witches' broom disease (WBD) of the cocoa tree, whose seeds are the source of chocolate. It is the most important phytopathological problem of cocoa-producing areas of the American continent, and has decimated the Brazilian cocoa industry. In Bahia (Brazil), M. perniciosa was identified in 1989 and, as a consequence of its spreading, the annual production of cocoa almonds dropped from 450,000 to 90,000 tons within 12 y, reducing export values from an all-time high of about US$ 1 billion to 110 million. The high incidence of WBD incapacitates Brazil to produce enough cocoa almonds even for the internal market, leading the country to import low-quality cocoa almonds mainly from African countries. Our work proposes an enzymatic treatment to increase the quality of that cocoa almonds and, consequently, to improve the quality of the chocolate produced and consumed in the country. © 2011 Institute of Food Technologists®

  1. Naval Research Laboratory 1984 Review.

    DTIC Science & Technology

    1985-07-16

    pulsed infrared comprehensive characterization of ultrahigh trans- sources and electronics for video signal process- parency fluoride glasses and...operates a video system through this port if desired. The optical bench in consisting of visible and infrared television cam- the trailer holds a high...resolution Fourier eras, a high-quality video cassette recorder and transform spectrometer to use in the receiving display, and a digitizer to convert

  2. Impacts of wildfire severity on hydraulic conductivity in forest, woodland, and grassland soils (Chapter 7)

    Treesearch

    Daniel G. Neary

    2011-01-01

    Forest, woodland, and grassland watersheds throughout the world are major sources of high quality water for human use because of the nature of these soils to infiltrate, store, and transmit most precipitation instead of quickly routing it to surface runoff. This characteristic of these wildland soils is due to normally high infiltration rates, porosities, and hydraulic...

  3. Overexpression of GmCaM4 in soybean enhances resistance to pathogens and tolerance to salt stress

    USDA-ARS?s Scientific Manuscript database

    Soybean (Glycine max (L.) Merr.) is the major oilseed crop in the world and is a main source of oil and high-quality protein for both humans and animals worldwide. Plant diseases inflict heavy losses on soybean yield that negatively impact the US economy. Implicit in the high economic value of this ...

  4. Passive MIMO Radar Detection

    DTIC Science & Technology

    2013-09-01

    investigated using recent results from random matrix theory. Equivalence is established between PMR networks without direct-path signals and passive...approach ignores a potentially useful source of information about the unknown transmit signals . This is particularly true in high-DNR scenarios, in...which the direct-path signal provides a high-quality reference that can be used for (noisy) matched filtering, as in the conventional approach. Thus

  5. The quality of our Nation's waters: Water quality in principal aquifers of the United States, 1991-2010

    USGS Publications Warehouse

    DeSimone, Leslie A.; McMahon, Peter B.; Rosen, Michael R.

    2015-01-01

    About 130 million people in the United States rely on groundwater for drinking water, and the need for high-quality drinking-water supplies becomes more urgent as our population grows. Although groundwater is a safe, reliable source of drinking water for millions of people nationwide, high concentrations of some chemical constituents can pose potential human-health concerns. Some of these contaminants come from the rocks and sediments of the aquifers themselves, and others are chemicals that we use in agriculture, industry, and day-to-day life. When groundwater supplies are contaminated, millions of dollars can be required for treatment so that the supplies can be usable. Contaminants in groundwater can also affect the health of our streams and valuable coastal waters. By knowing where contaminants occur in groundwater, what factors control contaminant concentrations, and what kinds of changes in groundwater quality might be expected in the future, we can ensure the availability and quality of this vital natural resource in the future.

  6. Using Lagrangian Coherent Structures to understand coastal water quality

    NASA Astrophysics Data System (ADS)

    Fiorentino, L. A.; Olascoaga, M. J.; Reniers, A.; Feng, Z.; Beron-Vera, F. J.; MacMahan, J. H.

    2012-09-01

    The accumulation of pollutants near the shoreline can result in low quality coastal water with negative effects on human health. To understand the role of mixing by tidal flows in coastal water quality we study the nearshore Lagrangian circulation. Specifically, we reveal Lagrangian Coherent Structures (LCSs), i.e., distinguished material curves which shape global mixing patterns and thus act as skeletons of the Lagrangian circulation. This is done using the recently developed geodesic theory of transport barriers. Particular focus is placed on Hobie Beach, a recreational subtropical marine beach located in Virginia Key, Miami, Florida. According to studies of water quality, Hobie Beach is characterized by high microbial levels. Possible sources of pollution in Hobie Beach include human bather shedding, dog fecal matter, runoff, and sand efflux at high tides. Consistent with the patterns formed by satellite-tracked drifter trajectories, the LCSs extracted from simulated currents reveal a Lagrangian circulation favoring the retention near the shoreline of pollutants released along the shoreline, which can help explain the low quality water registered at Hobie Beach.

  7. High performance top-gated ferroelectric field effect transistors based on two-dimensional ZnO nanosheets

    NASA Astrophysics Data System (ADS)

    Tian, Hongzheng; Wang, Xudong; Zhu, Yuankun; Liao, Lei; Wang, Xianying; Wang, Jianlu; Hu, Weida

    2017-01-01

    High quality ultrathin two-dimensional zinc oxide (ZnO) nanosheets (NSs) are synthesized, and the ZnO NS ferroelectric field effect transistors (FeFETs) are demonstrated based on the P(VDF-TrFE) polymer film used as the top gate insulating layer. The ZnO NSs exhibit a maximum field effect mobility of 588.9 cm2/Vs and a large transconductance of 2.5 μS due to their high crystalline quality and ultrathin two-dimensional structure. The polarization property of the P(VDF-TrFE) film is studied, and a remnant polarization of >100 μC/cm2 is achieved with a P(VDF-TrFE) thickness of 300 nm. Because of the ultrahigh remnant polarization field generated in the P(VDF-TrFE) film, the FeFETs show a large memory window of 16.9 V and a high source-drain on/off current ratio of more than 107 at zero gate voltage and a source-drain bias of 0.1 V. Furthermore, a retention time of >3000 s of the polarization state is obtained, inspiring a promising candidate for applications in data storage with non-volatile features.

  8. A data-driven approach for quality assessment of radiologic interpretations.

    PubMed

    Hsu, William; Han, Simon X; Arnold, Corey W; Bui, Alex At; Enzmann, Dieter R

    2016-04-01

    Given the increasing emphasis on delivering high-quality, cost-efficient healthcare, improved methodologies are needed to measure the accuracy and utility of ordered diagnostic examinations in achieving the appropriate diagnosis. Here, we present a data-driven approach for performing automated quality assessment of radiologic interpretations using other clinical information (e.g., pathology) as a reference standard for individual radiologists, subspecialty sections, imaging modalities, and entire departments. Downstream diagnostic conclusions from the electronic medical record are utilized as "truth" to which upstream diagnoses generated by radiology are compared. The described system automatically extracts and compares patient medical data to characterize concordance between clinical sources. Initial results are presented in the context of breast imaging, matching 18 101 radiologic interpretations with 301 pathology diagnoses and achieving a precision and recall of 84% and 92%, respectively. The presented data-driven method highlights the challenges of integrating multiple data sources and the application of information extraction tools to facilitate healthcare quality improvement. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  9. Scater: pre-processing, quality control, normalization and visualization of single-cell RNA-seq data in R.

    PubMed

    McCarthy, Davis J; Campbell, Kieran R; Lun, Aaron T L; Wills, Quin F

    2017-04-15

    Single-cell RNA sequencing (scRNA-seq) is increasingly used to study gene expression at the level of individual cells. However, preparing raw sequence data for further analysis is not a straightforward process. Biases, artifacts and other sources of unwanted variation are present in the data, requiring substantial time and effort to be spent on pre-processing, quality control (QC) and normalization. We have developed the R/Bioconductor package scater to facilitate rigorous pre-processing, quality control, normalization and visualization of scRNA-seq data. The package provides a convenient, flexible workflow to process raw sequencing reads into a high-quality expression dataset ready for downstream analysis. scater provides a rich suite of plotting tools for single-cell data and a flexible data structure that is compatible with existing tools and can be used as infrastructure for future software development. The open-source code, along with installation instructions, vignettes and case studies, is available through Bioconductor at http://bioconductor.org/packages/scater . davis@ebi.ac.uk. Supplementary data are available at Bioinformatics online. © The Author 2017. Published by Oxford University Press.

  10. Demographic, clinical, and quality of life variables related to embarrassment in veterans living with an intestinal stoma.

    PubMed

    Mitchell, Kimberly A; Rawl, Susan M; Schmidt, C Max; Grant, Marcia; Ko, Clifford Y; Baldwin, Carol M; Wendel, Christopher; Krouse, Robert S

    2007-01-01

    The study aims were to identify demographic, clinical, and quality of life variables related to embarrassment for people living with ostomies and to determine the experiences and/or feelings of veterans who were embarrassed by their ostomy. This was a cross-sectional, correlational study. A convenience sample of veterans (n = 239) living with ostomies from 3 VA medical centers was studied. The veterans were primarily Caucasian (84%), male (92%), and older (M = 69). The modified City of Hope Quality of Life-Ostomy questionnaire was used. Additionally, an open-ended question related to living with an ostomy was asked. The questionnaire packets were mailed to participants and self-administered. Approximately half of the participants (48%) rated their embarrassment as low, but 26% reported high embarrassment. Participants with high embarrassment were compared to those with low embarrassment on demographic, clinical, and quality of life variables. High embarrassment was associated with poorer total quality of life (P < .001) and poorer quality of life on the physical (P < .001), psychological (P < .001), social (P < .001), and spiritual (P < .001) subscales. Younger (P < .001) and unpartnered veterans (P < .001) were more likely to be highly embarrassed. Veterans with high embarrassment had higher anxiety (P < .001) and depression (P < .001), more difficulty with intimacy (P < .001), and felt more isolated (P < .001). Spiritual domain variables like hopefulness were associated with low embarrassment (P < .001). Sources of embarrassment included leakage, odor, and noise. Embarrassment may negatively impact a person's quality of life; therefore, the variables associated with high embarrassment should be recognized and addressed.

  11. Investigating the effects of point source and nonpoint source pollution on the water quality of the East River (Dongjiang) in South China

    USGS Publications Warehouse

    Wu, Yiping; Chen, Ji

    2013-01-01

    Understanding the physical processes of point source (PS) and nonpoint source (NPS) pollution is critical to evaluate river water quality and identify major pollutant sources in a watershed. In this study, we used the physically-based hydrological/water quality model, Soil and Water Assessment Tool, to investigate the influence of PS and NPS pollution on the water quality of the East River (Dongjiang in Chinese) in southern China. Our results indicate that NPS pollution was the dominant contribution (>94%) to nutrient loads except for mineral phosphorus (50%). A comprehensive Water Quality Index (WQI) computed using eight key water quality variables demonstrates that water quality is better upstream than downstream despite the higher level of ammonium nitrogen found in upstream waters. Also, the temporal (seasonal) and spatial distributions of nutrient loads clearly indicate the critical time period (from late dry season to early wet season) and pollution source areas within the basin (middle and downstream agricultural lands), which resource managers can use to accomplish substantial reduction of NPS pollutant loadings. Overall, this study helps our understanding of the relationship between human activities and pollutant loads and further contributes to decision support for local watershed managers to protect water quality in this region. In particular, the methods presented such as integrating WQI with watershed modeling and identifying the critical time period and pollutions source areas can be valuable for other researchers worldwide.

  12. Optimization of subculture and DNA extraction steps within the whole genome sequencing workflow for source tracking of Salmonella enterica and Listeria monocytogenes.

    PubMed

    Gimonet, Johan; Portmann, Anne-Catherine; Fournier, Coralie; Baert, Leen

    2018-06-16

    This work shows that an incubation time reduced to 4-5 h to prepare a culture for DNA extraction followed by an automated DNA extraction can shorten the hands-on time, the turnaround time by 30% and increase the throughput while maintaining the WGS quality assessed by high quality Single Nucleotide Polymorphism analysis. Copyright © 2018. Published by Elsevier B.V.

  13. Highly oxidized graphene oxide and methods for production thereof

    DOEpatents

    Tour, James M.; Kosynkin, Dmitry V.

    2016-08-30

    A highly oxidized form of graphene oxide and methods for production thereof are described in various embodiments of the present disclosure. In general, the methods include mixing a graphite source with a solution containing at least one oxidant and at least one protecting agent and then oxidizing the graphite source with the at least one oxidant in the presence of the at least one protecting agent to form the graphene oxide. Graphene oxide synthesized by the presently described methods is of a high structural quality that is more oxidized and maintains a higher proportion of aromatic rings and aromatic domains than does graphene oxide prepared in the absence of at least one protecting agent. Methods for reduction of graphene oxide into chemically converted graphene are also disclosed herein. The chemically converted graphene of the present disclosure is significantly more electrically conductive than is chemically converted graphene prepared from other sources of graphene oxide.

  14. The organic trace gas composition over South Korea as measured by PTR-ToF-MS during KORUS-AQ

    NASA Astrophysics Data System (ADS)

    Wisthaler, A.; Eichler, P.; Kaser, L.; Mikoviny, T.; Müller, M.

    2017-12-01

    Nonmethane organic gases (NMOGs) are important air quality constituents. Many of them act as precursors to ozone and fine particles and some NMOGs (e.g. benzene) are classified as air toxics. During the Korea-United States Air Quality (KORUS-AQ) study in May and June of 2016, we deployed a proton-transfer-reaction time-of-flight mass spectrometer (PTR-ToF-MS) aboard the NASA DC-8 for measuring NMOGs at high speed (10 Hz) and sensitivity (ppt levels). The aircraft sampled emissions from a variety of point and area sources (e.g. urban emissions from Seoul and Daegu, industrial emission from the Daesan and Ulsan complexes, biogenic emissions over central South Korea and agricultural fire emissions in the Western provinces) as well as the pollution inflow from the Yellow Sea. We will provide an overview of NMOG profiles associated with these sources, give an estimate of emission rates where possible, and discuss potential implications for local and regional air quality. We will further give examples on how NMOG tracers can be used for source characterization and highlight findings that should undergo future collaborative analyses within the KORUS-AQ Science Team.

  15. An Integrated Risk Management Model for Source Water Protection Areas

    PubMed Central

    Chiueh, Pei-Te; Shang, Wei-Ting; Lo, Shang-Lien

    2012-01-01

    Watersheds are recognized as the most effective management unit for the protection of water resources. For surface water supplies that use water from upstream watersheds, evaluating threats to water quality and implementing a watershed management plan are crucial for the maintenance of drinking water safe for humans. The aim of this article is to establish a risk assessment model that provides basic information for identifying critical pollutants and areas at high risk for degraded water quality. In this study, a quantitative risk model that uses hazard quotients for each water quality parameter was combined with a qualitative risk model that uses the relative risk level of potential pollution events in order to characterize the current condition and potential risk of watersheds providing drinking water. In a case study of Taipei Source Water Area in northern Taiwan, total coliforms and total phosphorus were the top two pollutants of concern. Intensive tea-growing and recreational activities around the riparian zone may contribute the greatest pollution to the watershed. Our risk assessment tool may be enhanced by developing, recording, and updating information on pollution sources in the water supply watersheds. Moreover, management authorities could use the resultant information to create watershed risk management plans. PMID:23202770

  16. Determination of equilibrium dissociation constants for recombinant antibodies by high-throughput affinity electrophoresis.

    PubMed

    Pan, Yuchen; Sackmann, Eric K; Wypisniak, Karolina; Hornsby, Michael; Datwani, Sammy S; Herr, Amy E

    2016-12-23

    High-quality immunoreagents enhance the performance and reproducibility of immunoassays and, in turn, the quality of both biological and clinical measurements. High quality recombinant immunoreagents are generated using antibody-phage display. One metric of antibody quality - the binding affinity - is quantified through the dissociation constant (K D ) of each recombinant antibody and the target antigen. To characterize the K D of recombinant antibodies and target antigen, we introduce affinity electrophoretic mobility shift assays (EMSAs) in a high-throughput format suitable for small volume samples. A microfluidic card comprised of free-standing polyacrylamide gel (fsPAG) separation lanes supports 384 concurrent EMSAs in 30 s using a single power source. Sample is dispensed onto the microfluidic EMSA card by acoustic droplet ejection (ADE), which reduces EMSA variability compared to sample dispensing using manual or pin tools. The K D for each of a six-member fragment antigen-binding fragment library is reported using ~25-fold less sample mass and ~5-fold less time than conventional heterogeneous assays. Given the form factor and performance of this micro- and mesofluidic workflow, we have developed a sample-sparing, high-throughput, solution-phase alternative for biomolecular affinity characterization.

  17. Determination of equilibrium dissociation constants for recombinant antibodies by high-throughput affinity electrophoresis

    PubMed Central

    Pan, Yuchen; Sackmann, Eric K.; Wypisniak, Karolina; Hornsby, Michael; Datwani, Sammy S.; Herr, Amy E.

    2016-01-01

    High-quality immunoreagents enhance the performance and reproducibility of immunoassays and, in turn, the quality of both biological and clinical measurements. High quality recombinant immunoreagents are generated using antibody-phage display. One metric of antibody quality – the binding affinity – is quantified through the dissociation constant (KD) of each recombinant antibody and the target antigen. To characterize the KD of recombinant antibodies and target antigen, we introduce affinity electrophoretic mobility shift assays (EMSAs) in a high-throughput format suitable for small volume samples. A microfluidic card comprised of free-standing polyacrylamide gel (fsPAG) separation lanes supports 384 concurrent EMSAs in 30 s using a single power source. Sample is dispensed onto the microfluidic EMSA card by acoustic droplet ejection (ADE), which reduces EMSA variability compared to sample dispensing using manual or pin tools. The KD for each of a six-member fragment antigen-binding fragment library is reported using ~25-fold less sample mass and ~5-fold less time than conventional heterogeneous assays. Given the form factor and performance of this micro- and mesofluidic workflow, we have developed a sample-sparing, high-throughput, solution-phase alternative for biomolecular affinity characterization. PMID:28008969

  18. 48 CFR 246.402 - Government contract quality assurance at source.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Government contract... ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CONTRACT MANAGEMENT QUALITY ASSURANCE Government Contract Quality Assurance 246.402 Government contract quality assurance at source. Do not require...

  19. Generating polarization-entangled photon pairs using cross-spliced birefringent fibers.

    PubMed

    Meyer-Scott, Evan; Roy, Vincent; Bourgoin, Jean-Philippe; Higgins, Brendon L; Shalm, Lynden K; Jennewein, Thomas

    2013-03-11

    We demonstrate a novel polarization-entangled photon-pair source based on standard birefringent polarization-maintaining optical fiber. The source consists of two stretches of fiber spliced together with perpendicular polarization axes, and has the potential to be fully fiber-based, with all bulk optics replaced with in-fiber equivalents. By modelling the temporal walk-off in the fibers, we implement compensation necessary for the photon creation processes in the two stretches of fiber to be indistinguishable. Our source subsequently produces a high quality entangled state having (92.2 ± 0.2) % fidelity with a maximally entangled Bell state.

  20. Characterizing Dissolved Organic Matter (DOM) Isolated From Specific Allochthonous and Autochthonous Sources in a North-Temperate Stream Ecosystem

    NASA Astrophysics Data System (ADS)

    Wong, J. C.; Williams, D.

    2009-05-01

    Detrital energy in temperate headwater streams is mainly derived from the annual input of leaf litter from the surrounding landscape. Presumably, its decomposition and other sources of autochthonous organic matter will change dissolved organic carbon (DOC) concentrations and dissolved organic matter (DOM) quality. To investigate this, DOM was leached from two allochthonous sources: white birch (Betula papyrifera) and white cedar (Thuja occidentalis); and one autochthonous source, streambed biofilm, for a period of 7 days on 3 separate occasions in fall 2007. As a second treatment, microorganisms from the water column were filtered out. Deciduous leaf litter was responsible for high, short-term increases to DOC concentrations whereas the amounts leached from conifer needles were relatively constant in each month. Using UV spectroscopy, changes to DOM characteristics like aromaticity, spectral slopes, and molecular weight were mainly determined by source and indicated a preferential use of the labile DOM pool by the microorganisms. Excitation-emission matrices (EEMs) collected using fluorescence spectroscopy suggested that cedar litter was an important source of protein-like fluorescence and that the nature of the fluorescing DOM components changed in the presence of microorganisms. This study demonstrates that simultaneous examination of DOC concentrations and DOM quality will allow a better understanding of the carbon dynamics that connect terrestrial with aquatic ecosystems.

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