High resolution time interval meter
Martin, A.D.
1986-05-09
Method and apparatus are provided for measuring the time interval between two events to a higher resolution than reliability available from conventional circuits and component. An internal clock pulse is provided at a frequency compatible with conventional component operating frequencies for reliable operation. Lumped constant delay circuits are provided for generating outputs at delay intervals corresponding to the desired high resolution. An initiation START pulse is input to generate first high resolution data. A termination STOP pulse is input to generate second high resolution data. Internal counters count at the low frequency internal clock pulse rate between the START and STOP pulses. The first and second high resolution data are logically combined to directly provide high resolution data to one counter and correct the count in the low resolution counter to obtain a high resolution time interval measurement.
A method for generating high resolution satellite image time series
NASA Astrophysics Data System (ADS)
Guo, Tao
2014-10-01
There is an increasing demand for satellite remote sensing data with both high spatial and temporal resolution in many applications. But it still is a challenge to simultaneously improve spatial resolution and temporal frequency due to the technical limits of current satellite observation systems. To this end, much R&D efforts have been ongoing for years and lead to some successes roughly in two aspects, one includes super resolution, pan-sharpen etc. methods which can effectively enhance the spatial resolution and generate good visual effects, but hardly preserve spectral signatures and result in inadequate analytical value, on the other hand, time interpolation is a straight forward method to increase temporal frequency, however it increase little informative contents in fact. In this paper we presented a novel method to simulate high resolution time series data by combing low resolution time series data and a very small number of high resolution data only. Our method starts with a pair of high and low resolution data set, and then a spatial registration is done by introducing LDA model to map high and low resolution pixels correspondingly. Afterwards, temporal change information is captured through a comparison of low resolution time series data, and then projected onto the high resolution data plane and assigned to each high resolution pixel according to the predefined temporal change patterns of each type of ground objects. Finally the simulated high resolution data is generated. A preliminary experiment shows that our method can simulate a high resolution data with a reasonable accuracy. The contribution of our method is to enable timely monitoring of temporal changes through analysis of time sequence of low resolution images only, and usage of costly high resolution data can be reduces as much as possible, and it presents a highly effective way to build up an economically operational monitoring solution for agriculture, forest, land use investigation, environment and etc. applications.
NASA Astrophysics Data System (ADS)
Leung, L.; Hagos, S. M.; Rauscher, S.; Ringler, T.
2012-12-01
This study compares two grid refinement approaches using global variable resolution model and nesting for high-resolution regional climate modeling. The global variable resolution model, Model for Prediction Across Scales (MPAS), and the limited area model, Weather Research and Forecasting (WRF) model, are compared in an idealized aqua-planet context with a focus on the spatial and temporal characteristics of tropical precipitation simulated by the models using the same physics package from the Community Atmosphere Model (CAM4). For MPAS, simulations have been performed with a quasi-uniform resolution global domain at coarse (1 degree) and high (0.25 degree) resolution, and a variable resolution domain with a high-resolution region at 0.25 degree configured inside a coarse resolution global domain at 1 degree resolution. Similarly, WRF has been configured to run on a coarse (1 degree) and high (0.25 degree) resolution tropical channel domain as well as a nested domain with a high-resolution region at 0.25 degree nested two-way inside the coarse resolution (1 degree) tropical channel. The variable resolution or nested simulations are compared against the high-resolution simulations that serve as virtual reality. Both MPAS and WRF simulate 20-day Kelvin waves propagating through the high-resolution domains fairly unaffected by the change in resolution. In addition, both models respond to increased resolution with enhanced precipitation. Grid refinement induces zonal asymmetry in precipitation (heating), accompanied by zonal anomalous Walker like circulations and standing Rossby wave signals. However, there are important differences between the anomalous patterns in MPAS and WRF due to differences in the grid refinement approaches and sensitivity of model physics to grid resolution. This study highlights the need for "scale aware" parameterizations in variable resolution and nested regional models.
Single sensor processing to obtain high resolution color component signals
NASA Technical Reports Server (NTRS)
Glenn, William E. (Inventor)
2010-01-01
A method for generating color video signals representative of color images of a scene includes the following steps: focusing light from the scene on an electronic image sensor via a filter having a tri-color filter pattern; producing, from outputs of the sensor, first and second relatively low resolution luminance signals; producing, from outputs of the sensor, a relatively high resolution luminance signal; producing, from a ratio of the relatively high resolution luminance signal to the first relatively low resolution luminance signal, a high band luminance component signal; producing, from outputs of the sensor, relatively low resolution color component signals; and combining each of the relatively low resolution color component signals with the high band luminance component signal to obtain relatively high resolution color component signals.
NASA Astrophysics Data System (ADS)
Unnikrishnan, C. K.; Rajeevan, M.; Rao, S. Vijaya Bhaskara
2016-06-01
The direct impact of high resolution land surface initialization on the forecast bias in a regional climate model in recent years over Indian summer monsoon region is investigated. Two sets of regional climate model simulations are performed, one with a coarse resolution land surface initial conditions and second one used a high resolution land surface data for initial condition. The results show that all monsoon years respond differently to the high resolution land surface initialization. The drought monsoon year 2009 and extended break periods were more sensitive to the high resolution land surface initialization. These results suggest that the drought monsoon year predictions can be improved with high resolution land surface initialization. Result also shows that there are differences in the response to the land surface initialization within the monsoon season. Case studies of heat wave and a monsoon depression simulation show that, the model biases were also improved with high resolution land surface initialization. These results show the need for a better land surface initialization strategy in high resolution regional models for monsoon forecasting.
A digital gigapixel large-format tile-scan camera.
Ben-Ezra, M
2011-01-01
Although the resolution of single-lens reflex (SLR) and medium-format digital cameras has increased in recent years, applications for cultural-heritage preservation and computational photography require even higher resolutions. Addressing this issue, a large-format cameras' large image planes can achieve very high resolution without compromising pixel size and thus can provide high-quality, high-resolution images.This digital large-format tile scan camera can acquire high-quality, high-resolution images of static scenes. It employs unique calibration techniques and a simple algorithm for focal-stack processing of very large images with significant magnification variations. The camera automatically collects overlapping focal stacks and processes them into a high-resolution, extended-depth-of-field image.
Very high resolution aerial films
NASA Astrophysics Data System (ADS)
Becker, Rolf
1986-11-01
The use of very high resolution aerial films in aerial photography is evaluated. Commonly used panchromatic, color, and CIR films and their high resolution equivalents are compared. Based on practical experience and systematic investigations, the very high image quality and improved height accuracy that can be achieved using these films are demonstrated. Advantages to be gained from this improvement and operational restrictions encountered when using high resolution film are discussed.
CNV detection method optimized for high-resolution arrayCGH by normality test.
Ahn, Jaegyoon; Yoon, Youngmi; Park, Chihyun; Park, Sanghyun
2012-04-01
High-resolution arrayCGH platform makes it possible to detect small gains and losses which previously could not be measured. However, current CNV detection tools fitted to early low-resolution data are not applicable to larger high-resolution data. When CNV detection tools are applied to high-resolution data, they suffer from high false-positives, which increases validation cost. Existing CNV detection tools also require optimal parameter values. In most cases, obtaining these values is a difficult task. This study developed a CNV detection algorithm that is optimized for high-resolution arrayCGH data. This tool operates up to 1500 times faster than existing tools on a high-resolution arrayCGH of whole human chromosomes which has 42 million probes whose average length is 50 bases, while preserving false positive/negative rates. The algorithm also uses a normality test, thereby removing the need for optimal parameters. To our knowledge, this is the first formulation for CNV detecting problems that results in a near-linear empirical overall complexity for real high-resolution data. Copyright © 2012 Elsevier Ltd. All rights reserved.
Lee, N J; Chung, M S; Jung, S C; Kim, H S; Choi, C-G; Kim, S J; Lee, D H; Suh, D C; Kwon, S U; Kang, D-W; Kim, J S
2016-12-01
High-resolution MR imaging has recently been introduced as a promising diagnostic modality in intracranial artery disease. Our aim was to compare high-resolution MR imaging with digital subtraction angiography for the characterization and diagnosis of various intracranial artery diseases. Thirty-seven patients who had undergone both high-resolution MR imaging and DSA for intracranial artery disease were enrolled in our study (August 2011 to April 2014). The time interval between the high-resolution MR imaging and DSA was within 1 month. The degree of stenosis and the minimal luminal diameter were independently measured by 2 observers in both DSA and high-resolution MR imaging, and the results were compared. Two observers independently diagnosed intracranial artery diseases on DSA and high-resolution MR imaging. The time interval between the diagnoses on DSA and high-resolution MR imaging was 2 weeks. Interobserver diagnostic agreement for each technique and intermodality diagnostic agreement for each observer were acquired. High-resolution MR imaging showed moderate-to-excellent agreement (interclass correlation coefficient = 0.892-0.949; κ = 0.548-0.614) and significant correlations (R = 0.766-892) with DSA on the degree of stenosis and minimal luminal diameter. The interobserver diagnostic agreement was good for DSA (κ = 0.643) and excellent for high-resolution MR imaging (κ = 0.818). The intermodality diagnostic agreement was good (κ = 0.704) for observer 1 and moderate (κ = 0.579) for observer 2, respectively. High-resolution MR imaging may be an imaging method comparable with DSA for the characterization and diagnosis of various intracranial artery diseases. © 2016 by American Journal of Neuroradiology.
Image resolution enhancement via image restoration using neural network
NASA Astrophysics Data System (ADS)
Zhang, Shuangteng; Lu, Yihong
2011-04-01
Image super-resolution aims to obtain a high-quality image at a resolution that is higher than that of the original coarse one. This paper presents a new neural network-based method for image super-resolution. In this technique, the super-resolution is considered as an inverse problem. An observation model that closely follows the physical image acquisition process is established to solve the problem. Based on this model, a cost function is created and minimized by a Hopfield neural network to produce high-resolution images from the corresponding low-resolution ones. Not like some other single frame super-resolution techniques, this technique takes into consideration point spread function blurring as well as additive noise and therefore generates high-resolution images with more preserved or restored image details. Experimental results demonstrate that the high-resolution images obtained by this technique have a very high quality in terms of PSNR and visually look more pleasant.
Guner, Huseyin; Close, Patrick L; Cai, Wenxuan; Zhang, Han; Peng, Ying; Gregorich, Zachery R; Ge, Ying
2014-03-01
The rapid advancements in mass spectrometry (MS) instrumentation, particularly in Fourier transform (FT) MS, have made the acquisition of high-resolution and high-accuracy mass measurements routine. However, the software tools for the interpretation of high-resolution MS data are underdeveloped. Although several algorithms for the automatic processing of high-resolution MS data are available, there is still an urgent need for a user-friendly interface with functions that allow users to visualize and validate the computational output. Therefore, we have developed MASH Suite, a user-friendly and versatile software interface for processing high-resolution MS data. MASH Suite contains a wide range of features that allow users to easily navigate through data analysis, visualize complex high-resolution MS data, and manually validate automatically processed results. Furthermore, it provides easy, fast, and reliable interpretation of top-down, middle-down, and bottom-up MS data. MASH Suite is convenient, easily operated, and freely available. It can greatly facilitate the comprehensive interpretation and validation of high-resolution MS data with high accuracy and reliability.
Von Dreele, Robert B.; D'Amico, Kevin
2006-10-31
A process is provided for the high throughput screening of binding of ligands to macromolecules using high resolution powder diffraction data including producing a first sample slurry of a selected polycrystalline macromolecule material and a solvent, producing a second sample slurry of a selected polycrystalline macromolecule material, one or more ligands and the solvent, obtaining a high resolution powder diffraction pattern on each of said first sample slurry and the second sample slurry, and, comparing the high resolution powder diffraction pattern of the first sample slurry and the high resolution powder diffraction pattern of the second sample slurry whereby a difference in the high resolution powder diffraction patterns of the first sample slurry and the second sample slurry provides a positive indication for the formation of a complex between the selected polycrystalline macromolecule material and at least one of the one or more ligands.
Higashiura, Akifumi; Ohta, Kazunori; Masaki, Mika; Sato, Masaru; Inaka, Koji; Tanaka, Hiroaki; Nakagawa, Atsushi
2013-11-01
Recently, many technical improvements in macromolecular X-ray crystallography have increased the number of structures deposited in the Protein Data Bank and improved the resolution limit of protein structures. Almost all high-resolution structures have been determined using a synchrotron radiation source in conjunction with cryocooling techniques, which are required in order to minimize radiation damage. However, optimization of cryoprotectant conditions is a time-consuming and difficult step. To overcome this problem, the high-pressure cryocooling method was developed (Kim et al., 2005) and successfully applied to many protein-structure analyses. In this report, using the high-pressure cryocooling method, the X-ray crystal structure of bovine H-protein was determined at 0.86 Å resolution. Structural comparisons between high- and ambient-pressure cryocooled crystals at ultra-high resolution illustrate the versatility of this technique. This is the first ultra-high-resolution X-ray structure obtained using the high-pressure cryocooling method.
Gas scintillation glass GEM detector for high-resolution X-ray imaging and CT
NASA Astrophysics Data System (ADS)
Fujiwara, T.; Mitsuya, Y.; Fushie, T.; Murata, K.; Kawamura, A.; Koishikawa, A.; Toyokawa, H.; Takahashi, H.
2017-04-01
A high-spatial-resolution X-ray-imaging gaseous detector has been developed with a single high-gas-gain glass gas electron multiplier (G-GEM), scintillation gas, and optical camera. High-resolution X-ray imaging of soft elements is performed with a spatial resolution of 281 μm rms and an effective area of 100×100 mm. In addition, high-resolution X-ray 3D computed tomography (CT) is successfully demonstrated with the gaseous detector. It shows high sensitivity to low-energy X-rays, which results in high-contrast radiographs of objects containing elements with low atomic numbers. In addition, the high yield of scintillation light enables fast X-ray imaging, which is an advantage for constructing CT images with low-energy X-rays.
Satellite image fusion based on principal component analysis and high-pass filtering.
Metwalli, Mohamed R; Nasr, Ayman H; Allah, Osama S Farag; El-Rabaie, S; Abd El-Samie, Fathi E
2010-06-01
This paper presents an integrated method for the fusion of satellite images. Several commercial earth observation satellites carry dual-resolution sensors, which provide high spatial resolution or simply high-resolution (HR) panchromatic (pan) images and low-resolution (LR) multi-spectral (MS) images. Image fusion methods are therefore required to integrate a high-spectral-resolution MS image with a high-spatial-resolution pan image to produce a pan-sharpened image with high spectral and spatial resolutions. Some image fusion methods such as the intensity, hue, and saturation (IHS) method, the principal component analysis (PCA) method, and the Brovey transform (BT) method provide HR MS images, but with low spectral quality. Another family of image fusion methods, such as the high-pass-filtering (HPF) method, operates on the basis of the injection of high frequency components from the HR pan image into the MS image. This family of methods provides less spectral distortion. In this paper, we propose the integration of the PCA method and the HPF method to provide a pan-sharpened MS image with superior spatial resolution and less spectral distortion. The experimental results show that the proposed fusion method retains the spectral characteristics of the MS image and, at the same time, improves the spatial resolution of the pan-sharpened image.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jun, Ji Hyun; Song, Zhihong; Liu, Zhenjiu
High-spatial resolution and high-mass resolution techniques are developed and adopted for the mass spectrometric imaging of epicuticular lipids on the surface of Arabidopsis thaliana. Single cell level spatial resolution of {approx}12 {micro}m was achieved by reducing the laser beam size by using an optical fiber with 25 {micro}m core diameter in a vacuum matrix-assisted laser desorption ionization-linear ion trap (vMALDI-LTQ) mass spectrometer and improved matrix application using an oscillating capillary nebulizer. Fine chemical images of a whole flower were visualized in this high spatial resolution showing substructure of an anther and single pollen grains at the stigma and anthers. Themore » LTQ-Orbitrap with a MALDI ion source was adopted to achieve MS imaging in high mass resolution. Specifically, isobaric silver ion adducts of C29 alkane (m/z 515.3741) and C28 aldehyde (m/z 515.3377), indistinguishable in low-resolution LTQ, can now be clearly distinguished and their chemical images could be separately constructed. In the application to roots, the high spatial resolution allowed molecular MS imaging of secondary roots and the high mass resolution allowed direct identification of lipid metabolites on root surfaces.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wei, Zhiliang; Lin, Liangjie; Lin, Yanqin, E-mail: linyq@xmu.edu.cn, E-mail: chenz@xmu.edu.cn
2014-09-29
In nuclear magnetic resonance (NMR) technique, it is of great necessity and importance to obtain high-resolution spectra, especially under inhomogeneous magnetic fields. In this study, a method based on partial homogeneity is proposed for retrieving high-resolution one-dimensional NMR spectra under inhomogeneous fields. Signals from series of small voxels, which characterize high resolution due to small sizes, are recorded simultaneously. Then, an inhomogeneity correction algorithm is developed based on pattern recognition to correct the influence brought by field inhomogeneity automatically, thus yielding high-resolution information. Experiments on chemical solutions and fish spawn were carried out to demonstrate the performance of the proposedmore » method. The proposed method serves as a single radiofrequency pulse high-resolution NMR spectroscopy under inhomogeneous fields and may provide an alternative of obtaining high-resolution spectra of in vivo living systems or chemical-reaction systems, where performances of conventional techniques are usually degenerated by field inhomogeneity.« less
Attention Modifies Spatial Resolution According to Task Demands.
Barbot, Antoine; Carrasco, Marisa
2017-03-01
How does visual attention affect spatial resolution? In texture-segmentation tasks, exogenous (involuntary) attention automatically increases resolution at the attended location, which improves performance where resolution is too low (at the periphery) but impairs performance where resolution is already too high (at central locations). Conversely, endogenous (voluntary) attention improves performance at all eccentricities, which suggests a more flexible mechanism. Here, using selective adaptation to spatial frequency, we investigated the mechanism by which endogenous attention benefits performance in resolution tasks. Participants detected a texture target that could appear at several eccentricities. Adapting to high or low spatial frequencies selectively affected performance in a manner consistent with changes in resolution. Moreover, adapting to high, but not low, frequencies mitigated the attentional benefit at central locations where resolution was too high; this shows that attention can improve performance by decreasing resolution. Altogether, our results indicate that endogenous attention benefits performance by modulating the contribution of high-frequency information in order to flexibly adjust spatial resolution according to task demands.
Attention Modifies Spatial Resolution According to Task Demands
Barbot, Antoine; Carrasco, Marisa
2017-01-01
How does visual attention affect spatial resolution? In texture-segmentation tasks, exogenous (involuntary) attention automatically increases resolution at the attended location, which improves performance where resolution is too low (at the periphery) but impairs performance where resolution is already too high (at central locations). Conversely, endogenous (voluntary) attention improves performance at all eccentricities, which suggests a more flexible mechanism. Here, using selective adaptation to spatial frequency, we investigated the mechanism by which endogenous attention benefits performance in resolution tasks. Participants detected a texture target that could appear at several eccentricities. Adapting to high or low spatial frequencies selectively affected performance in a manner consistent with changes in resolution. Moreover, adapting to high, but not low, frequencies mitigated the attentional benefit at central locations where resolution was too high; this shows that attention can improve performance by decreasing resolution. Altogether, our results indicate that endogenous attention benefits performance by modulating the contribution of high-frequency information in order to flexibly adjust spatial resolution according to task demands. PMID:28118103
NASA Technical Reports Server (NTRS)
Mareboyana, Manohar; Le Moigne-Stewart, Jacqueline; Bennett, Jerome
2016-01-01
In this paper, we demonstrate a simple algorithm that projects low resolution (LR) images differing in subpixel shifts on a high resolution (HR) also called super resolution (SR) grid. The algorithm is very effective in accuracy as well as time efficiency. A number of spatial interpolation techniques using nearest neighbor, inverse-distance weighted averages, Radial Basis Functions (RBF) etc. used in projection yield comparable results. For best accuracy of reconstructing SR image by a factor of two requires four LR images differing in four independent subpixel shifts. The algorithm has two steps: i) registration of low resolution images and (ii) shifting the low resolution images to align with reference image and projecting them on high resolution grid based on the shifts of each low resolution image using different interpolation techniques. Experiments are conducted by simulating low resolution images by subpixel shifts and subsampling of original high resolution image and the reconstructing the high resolution images from the simulated low resolution images. The results of accuracy of reconstruction are compared by using mean squared error measure between original high resolution image and reconstructed image. The algorithm was tested on remote sensing images and found to outperform previously proposed techniques such as Iterative Back Projection algorithm (IBP), Maximum Likelihood (ML), and Maximum a posterior (MAP) algorithms. The algorithm is robust and is not overly sensitive to the registration inaccuracies.
NASA Astrophysics Data System (ADS)
Roesler, E. L.; Bosler, P. A.; Taylor, M.
2016-12-01
The impact of strong extratropical storms on coastal communities is large, and the extent to which storms will change with a warming Arctic is unknown. Understanding storms in reanalysis and in climate models is important for future predictions. We know that the number of detected Arctic storms in reanalysis is sensitive to grid resolution. To understand Arctic storm sensitivity to resolution in climate models, we describe simulations designed to identify and compare Arctic storms at uniform low resolution (1 degree), at uniform high resolution (1/8 degree), and at variable resolution (1 degree to 1/8 degree). High-resolution simulations resolve more fine-scale structure and extremes, such as storms, in the atmosphere than a uniform low-resolution simulation. However, the computational cost of running a globally uniform high-resolution simulation is often prohibitive. The variable resolution tool in atmospheric general circulation models permits regional high-resolution solutions at a fraction of the computational cost. The storms are identified using the open-source search algorithm, Stride Search. The uniform high-resolution simulation has over 50% more storms than the uniform low-resolution and over 25% more storms than the variable resolution simulations. Storm statistics from each of the simulations is presented and compared with reanalysis. We propose variable resolution as a cost-effective means of investigating physics/dynamics coupling in the Arctic environment. Future work will include comparisons with observed storms to investigate tuning parameters for high resolution models. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000. SAND2016-7402 A
NASA Astrophysics Data System (ADS)
Joers, James M.
The use of magic angle spinning to obtain high resolution solid state spectra has been well documented. This resolution occurs by coherently averaging the chemical shift anisotropy and dipolar interactions to zero over the period of a full rotation. While this allows for higher resolution, the structural information is seemingly lost to the spectrometer eye. Thus, high resolution spectra and structural information appear to be mutually exlusive. Recently, the push in solid state NMR is the development of recoupling techniques which afford both high resolution and structural information. The following dissertation demonstrates the feasibility of implementing such experiments in solving real world problems, and is centered on devising a method to recover homonuclear dipolar interactions in the high resolution regime.
O-space with high resolution readouts outperforms radial imaging.
Wang, Haifeng; Tam, Leo; Kopanoglu, Emre; Peters, Dana C; Constable, R Todd; Galiana, Gigi
2017-04-01
While O-Space imaging is well known to accelerate image acquisition beyond traditional Cartesian sampling, its advantages compared to undersampled radial imaging, the linear trajectory most akin to O-Space imaging, have not been detailed. In addition, previous studies have focused on ultrafast imaging with very high acceleration factors and relatively low resolution. The purpose of this work is to directly compare O-Space and radial imaging in their potential to deliver highly undersampled images of high resolution and minimal artifacts, as needed for diagnostic applications. We report that the greatest advantages to O-Space imaging are observed with extended data acquisition readouts. A sampling strategy that uses high resolution readouts is presented and applied to compare the potential of radial and O-Space sequences to generate high resolution images at high undersampling factors. Simulations and phantom studies were performed to investigate whether use of extended readout windows in O-Space imaging would increase k-space sampling and improve image quality, compared to radial imaging. Experimental O-Space images acquired with high resolution readouts show fewer artifacts and greater sharpness than radial imaging with equivalent scan parameters. Radial images taken with longer readouts show stronger undersampling artifacts, which can cause small or subtle image features to disappear. These features are preserved in a comparable O-Space image. High resolution O-Space imaging yields highly undersampled images of high resolution and minimal artifacts. The additional nonlinear gradient field improves image quality beyond conventional radial imaging. Copyright © 2016 Elsevier Inc. All rights reserved.
Olivier, Scot S.; Werner, John S.; Zawadzki, Robert J.; Laut, Sophie P.; Jones, Steven M.
2010-09-07
This invention permits retinal images to be acquired at high speed and with unprecedented resolution in three dimensions (4.times.4.times.6 .mu.m). The instrument achieves high lateral resolution by using adaptive optics to correct optical aberrations of the human eye in real time. High axial resolution and high speed are made possible by the use of Fourier-domain optical coherence tomography. Using this system, we have demonstrated the ability to image microscopic blood vessels and the cone photoreceptor mosaic.
Whole-animal imaging with high spatio-temporal resolution
NASA Astrophysics Data System (ADS)
Chhetri, Raghav; Amat, Fernando; Wan, Yinan; Höckendorf, Burkhard; Lemon, William C.; Keller, Philipp J.
2016-03-01
We developed isotropic multiview (IsoView) light-sheet microscopy in order to image fast cellular dynamics, such as cell movements in an entire developing embryo or neuronal activity throughput an entire brain or nervous system, with high resolution in all dimensions, high imaging speeds, good physical coverage and low photo-damage. To achieve high temporal resolution and high spatial resolution at the same time, IsoView microscopy rapidly images large specimens via simultaneous light-sheet illumination and fluorescence detection along four orthogonal directions. In a post-processing step, these four views are then combined by means of high-throughput multiview deconvolution to yield images with a system resolution of ≤ 450 nm in all three dimensions. Using IsoView microscopy, we performed whole-animal functional imaging of Drosophila embryos and larvae at a spatial resolution of 1.1-2.5 μm and at a temporal resolution of 2 Hz for up to 9 hours. We also performed whole-brain functional imaging in larval zebrafish and multicolor imaging of fast cellular dynamics across entire, gastrulating Drosophila embryos with isotropic, sub-cellular resolution. Compared with conventional (spatially anisotropic) light-sheet microscopy, IsoView microscopy improves spatial resolution at least sevenfold and decreases resolution anisotropy at least threefold. Compared with existing high-resolution light-sheet techniques, such as lattice lightsheet microscopy or diSPIM, IsoView microscopy effectively doubles the penetration depth and provides subsecond temporal resolution for specimens 400-fold larger than could previously be imaged.
An atlas of high-resolution IRAS maps on nearby galaxies
NASA Technical Reports Server (NTRS)
Rice, Walter
1993-01-01
An atlas of far-infrared IRAS maps with near 1 arcmin angular resolution of 30 optically large galaxies is presented. The high-resolution IRAS maps were produced with the Maximum Correlation Method (MCM) image construction and enhancement technique developed at IPAC. The MCM technique, which recovers the spatial information contained in the overlapping detector data samples of the IRAS all-sky survey scans, is outlined and tests to verify the structural reliability and photometric integrity of the high-resolution maps are presented. The infrared structure revealed in individual galaxies is discussed. The atlas complements the IRAS Nearby Galaxy High-Resolution Image Atlas, the high-resolution galaxy images encoded in FITS format, which is provided to the astronomical community as an IPAC product.
NASA Technical Reports Server (NTRS)
1987-01-01
The high-resolution imaging spectrometer (HIRIS) is an Earth Observing System (EOS) sensor developed for high spatial and spectral resolution. It can acquire more information in the 0.4 to 2.5 micrometer spectral region than any other sensor yet envisioned. Its capability for critical sampling at high spatial resolution makes it an ideal complement to the MODIS (moderate-resolution imaging spectrometer) and HMMR (high-resolution multifrequency microwave radiometer), lower resolution sensors designed for repetitive coverage. With HIRIS it is possible to observe transient processes in a multistage remote sensing strategy for Earth observations on a global scale. The objectives, science requirements, and current sensor design of the HIRIS are discussed along with the synergism of the sensor with other EOS instruments and data handling and processing requirements.
NASA Astrophysics Data System (ADS)
Zarzycki, C. M.; Gettelman, A.; Callaghan, P.
2017-12-01
Accurately predicting weather extremes such as precipitation (floods and droughts) and temperature (heat waves) requires high resolution to resolve mesoscale dynamics and topography at horizontal scales of 10-30km. Simulating such resolutions globally for climate scales (years to decades) remains computationally impractical. Simulating only a small region of the planet is more tractable at these scales for climate applications. This work describes global simulations using variable-resolution static meshes with multiple dynamical cores that target the continental United States using developmental versions of the Community Earth System Model version 2 (CESM2). CESM2 is tested in idealized, aquaplanet and full physics configurations to evaluate variable mesh simulations against uniform high and uniform low resolution simulations at resolutions down to 15km. Different physical parameterization suites are also evaluated to gauge their sensitivity to resolution. Idealized variable-resolution mesh cases compare well to high resolution tests. More recent versions of the atmospheric physics, including cloud schemes for CESM2, are more stable with respect to changes in horizontal resolution. Most of the sensitivity is due to sensitivity to timestep and interactions between deep convection and large scale condensation, expected from the closure methods. The resulting full physics model produces a comparable climate to the global low resolution mesh and similar high frequency statistics in the high resolution region. Some biases are reduced (orographic precipitation in the western United States), but biases do not necessarily go away at high resolution (e.g. summertime JJA surface Temp). The simulations are able to reproduce uniform high resolution results, making them an effective tool for regional climate studies and are available in CESM2.
NASA Astrophysics Data System (ADS)
Dore, A. J.; Kryza, M.; Hall, J. R.; Hallsworth, S.; Keller, V. J. D.; Vieno, M.; Sutton, M. A.
2011-12-01
The Fine Resolution Atmospheric Multi-pollutant Exchange model (FRAME) has been applied to model the spatial distribution of nitrogen deposition and air concentration over the UK at a 1 km spatial resolution. The modelled deposition and concentration data were gridded at resolutions of 1 km, 5 km and 50 km to test the sensitivity of calculations of the exceedance of critical loads for nitrogen deposition to the deposition data resolution. The modelled concentrations of NO2 were validated by comparison with measurements from the rural sites in the national monitoring network and were found to achieve better agreement with the high resolution 1 km data. High resolution plots were found to represent a more physically realistic distribution of nitrogen air concentrations and deposition resulting from use of 1 km resolution precipitation and emissions data as compared to 5 km resolution data. Summary statistics for national scale exceedance of the critical load for nitrogen deposition were not highly sensitive to the grid resolution of the deposition data but did show greater area exceedance with coarser grid resolution due to spatial averaging of high nitrogen deposition hot spots. Local scale deposition at individual Sites of Special Scientific Interest and high precipitation upland sites was sensitive to choice of grid resolution of deposition data. Use of high resolution data tended to generate lower deposition values in sink areas for nitrogen dry deposition (Sites of Scientific Interest) and higher values in high precipitation upland areas. In areas with generally low exceedance (Scotland) and for certain vegetation types (montane), the exceedance statistics were more sensitive to model data resolution.
NASA Astrophysics Data System (ADS)
Dore, A. J.; Kryza, M.; Hall, J. R.; Hallsworth, S.; Keller, V. J. D.; Vieno, M.; Sutton, M. A.
2012-05-01
The Fine Resolution Atmospheric Multi-pollutant Exchange model (FRAME) was applied to model the spatial distribution of reactive nitrogen deposition and air concentration over the United Kingdom at a 1 km spatial resolution. The modelled deposition and concentration data were gridded at resolutions of 1 km, 5 km and 50 km to test the sensitivity of calculations of the exceedance of critical loads for nitrogen deposition to the deposition data resolution. The modelled concentrations of NO2 were validated by comparison with measurements from the rural sites in the national monitoring network and were found to achieve better agreement with the high resolution 1 km data. High resolution plots were found to represent a more physically realistic distribution of reactive nitrogen air concentrations and deposition resulting from use of 1 km resolution precipitation and emissions data as compared to 5 km resolution data. Summary statistics for national scale exceedance of the critical load for nitrogen deposition were not highly sensitive to the grid resolution of the deposition data but did show greater area exceedance with coarser grid resolution due to spatial averaging of high nitrogen deposition hot spots. Local scale deposition at individual Sites of Special Scientific Interest and high precipitation upland sites was sensitive to choice of grid resolution of deposition data. Use of high resolution data tended to generate lower deposition values in sink areas for nitrogen dry deposition (Sites of Scientific Interest) and higher values in high precipitation upland areas. In areas with generally low exceedance (Scotland) and for certain vegetation types (montane), the exceedance statistics were more sensitive to model data resolution.
NREL: International Activities - Afghanistan Resource Maps
facilities, load centers, terrain conditions, and land use. The high-resolution (1-km) annual wind power maps . The high-resolution (10-km) annual and seasonal solar resource maps were developed using weather -km Resolution Annual Maps (Direct) Low-Res (JPG 104 KB) | High-Res (ZIP 330 KB) 40-km Resolution
Hu, Zhen-Hua; Huang, Teng; Wang, Ying-Ping; Ding, Lei; Zheng, Hai-Yang; Fang, Li
2011-06-01
Taking solar source as radiation in the near-infrared high-resolution absorption spectrum is widely used in remote sensing of atmospheric parameters. The present paper will take retrieval of the concentration of CO2 for example, and study the effect of solar spectra resolution. Retrieving concentrations of CO2 by using high resolution absorption spectra, a method which uses the program provided by AER to calculate the solar spectra at the top of atmosphere as radiation and combine with the HRATS (high resolution atmospheric transmission simulation) to simulate retrieving concentration of CO2. Numerical simulation shows that the accuracy of solar spectrum is important to retrieval, especially in the hyper-resolution spectral retrieavl, and the error of retrieval concentration has poor linear relation with the resolution of observation, but there is a tendency that the decrease in the resolution requires low resolution of solar spectrum. In order to retrieve the concentration of CO2 of atmosphere, the authors' should take full advantage of high-resolution solar spectrum at the top of atmosphere.
Collection and Analysis of Crowd Data with Aerial, Rooftop, and Ground Views
2014-11-10
collected these datasets using different aircrafts. Erista 8 HL OctaCopter is a heavy-lift aerial platform capable of using high-resolution cinema ...is another high-resolution camera that is cinema grade and high quality, with the capability of capturing videos with 4K resolution at 30 frames per...292.58 Imaging Systems and Accessories Blackmagic Production Camera 4 Crowd Counting using 4K Cameras High resolution cinema grade digital video
a Spiral-Based Downscaling Method for Generating 30 M Time Series Image Data
NASA Astrophysics Data System (ADS)
Liu, B.; Chen, J.; Xing, H.; Wu, H.; Zhang, J.
2017-09-01
The spatial detail and updating frequency of land cover data are important factors influencing land surface dynamic monitoring applications in high spatial resolution scale. However, the fragmentized patches and seasonal variable of some land cover types (e. g. small crop field, wetland) make it labor-intensive and difficult in the generation of land cover data. Utilizing the high spatial resolution multi-temporal image data is a possible solution. Unfortunately, the spatial and temporal resolution of available remote sensing data like Landsat or MODIS datasets can hardly satisfy the minimum mapping unit and frequency of current land cover mapping / updating at the same time. The generation of high resolution time series may be a compromise to cover the shortage in land cover updating process. One of popular way is to downscale multi-temporal MODIS data with other high spatial resolution auxiliary data like Landsat. But the usual manner of downscaling pixel based on a window may lead to the underdetermined problem in heterogeneous area, result in the uncertainty of some high spatial resolution pixels. Therefore, the downscaled multi-temporal data can hardly reach high spatial resolution as Landsat data. A spiral based method was introduced to downscale low spatial and high temporal resolution image data to high spatial and high temporal resolution image data. By the way of searching the similar pixels around the adjacent region based on the spiral, the pixel set was made up in the adjacent region pixel by pixel. The underdetermined problem is prevented to a large extent from solving the linear system when adopting the pixel set constructed. With the help of ordinary least squares, the method inverted the endmember values of linear system. The high spatial resolution image was reconstructed on the basis of high spatial resolution class map and the endmember values band by band. Then, the high spatial resolution time series was formed with these high spatial resolution images image by image. Simulated experiment and remote sensing image downscaling experiment were conducted. In simulated experiment, the 30 meters class map dataset Globeland30 was adopted to investigate the effect on avoid the underdetermined problem in downscaling procedure and a comparison between spiral and window was conducted. Further, the MODIS NDVI and Landsat image data was adopted to generate the 30m time series NDVI in remote sensing image downscaling experiment. Simulated experiment results showed that the proposed method had a robust performance in downscaling pixel in heterogeneous region and indicated that it was superior to the traditional window-based methods. The high resolution time series generated may be a benefit to the mapping and updating of land cover data.
Assessment of prediction skill in equatorial Pacific Ocean in high resolution model of CFS
NASA Astrophysics Data System (ADS)
Arora, Anika; Rao, Suryachandra A.; Pillai, Prasanth; Dhakate, Ashish; Salunke, Kiran; Srivastava, Ankur
2018-01-01
The effect of increasing atmospheric resolution on prediction skill of El Niño southern oscillation phenomenon in climate forecast system model is explored in this paper. Improvement in prediction skill for sea surface temperature (SST) and winds at all leads compared to low resolution model in the tropical Indo-Pacific basin is observed. High resolution model is able to capture extreme events reasonably well. As a result, the signal to noise ratio is improved in the high resolution model. However, spring predictability barrier (SPB) for summer months in Nino 3 and Nino 3.4 region is stronger in high resolution model, in spite of improvement in overall prediction skill and dynamics everywhere else. Anomaly correlation coefficient of SST in high resolution model with observations in Nino 3.4 region targeting boreal summer months when predicted at lead times of 3-8 months in advance decreased compared its lower resolution counterpart. It is noted that higher variance of winds predicted in spring season over central equatorial Pacific compared to observed variance of winds results in stronger than normal response on subsurface ocean, hence increases SPB for boreal summer months in high resolution model.
Introducing Graduate Students to High-Resolution Mass Spectrometry (HRMS) Using a Hands-On Approach
ERIC Educational Resources Information Center
Stock, Naomi L.
2017-01-01
High-resolution mass spectrometry (HRMS) features both high resolution and high mass accuracy and is a powerful tool for the analysis and quantitation of compounds, determination of elemental compositions, and identification of unknowns. A hands-on laboratory experiment for upper-level undergraduate and graduate students to investigate HRMS is…
Transmission/Scanning Transmission Electron Microscopy | Materials Science
imaging such as high resolution TEM. Transmission electron diffraction patterns help to determine the microstructure of a material and its defects. Phase-contrast imaging or high-resolution (HR) TEM imaging gives high scattering angle can be collected to form high-resolution, chemically sensitive, atomic number (Z
NREL: International Activities - Pakistan Resource Maps
. The high-resolution (1-km) annual wind power maps were developed using a numerical modeling approach along with NREL's empirical validation methodology. The high-resolution (10-km) annual and seasonal KB) | High-Res (ZIP 281 KB) 40-km Resolution Annual Maps (Direct) Low-Res (JPG 156 KB) | High-Res
Machine Learning Predictions of a Multiresolution Climate Model Ensemble
NASA Astrophysics Data System (ADS)
Anderson, Gemma J.; Lucas, Donald D.
2018-05-01
Statistical models of high-resolution climate models are useful for many purposes, including sensitivity and uncertainty analyses, but building them can be computationally prohibitive. We generated a unique multiresolution perturbed parameter ensemble of a global climate model. We use a novel application of a machine learning technique known as random forests to train a statistical model on the ensemble to make high-resolution model predictions of two important quantities: global mean top-of-atmosphere energy flux and precipitation. The random forests leverage cheaper low-resolution simulations, greatly reducing the number of high-resolution simulations required to train the statistical model. We demonstrate that high-resolution predictions of these quantities can be obtained by training on an ensemble that includes only a small number of high-resolution simulations. We also find that global annually averaged precipitation is more sensitive to resolution changes than to any of the model parameters considered.
NASA Astrophysics Data System (ADS)
Luo, Shouhua; Shen, Tao; Sun, Yi; Li, Jing; Li, Guang; Tang, Xiangyang
2018-04-01
In high resolution (microscopic) CT applications, the scan field of view should cover the entire specimen or sample to allow complete data acquisition and image reconstruction. However, truncation may occur in projection data and results in artifacts in reconstructed images. In this study, we propose a low resolution image constrained reconstruction algorithm (LRICR) for interior tomography in microscopic CT at high resolution. In general, the multi-resolution acquisition based methods can be employed to solve the data truncation problem if the project data acquired at low resolution are utilized to fill up the truncated projection data acquired at high resolution. However, most existing methods place quite strict restrictions on the data acquisition geometry, which greatly limits their utility in practice. In the proposed LRICR algorithm, full and partial data acquisition (scan) at low and high resolutions, respectively, are carried out. Using the image reconstructed from sparse projection data acquired at low resolution as the prior, a microscopic image at high resolution is reconstructed from the truncated projection data acquired at high resolution. Two synthesized digital phantoms, a raw bamboo culm and a specimen of mouse femur, were utilized to evaluate and verify performance of the proposed LRICR algorithm. Compared with the conventional TV minimization based algorithm and the multi-resolution scout-reconstruction algorithm, the proposed LRICR algorithm shows significant improvement in reduction of the artifacts caused by data truncation, providing a practical solution for high quality and reliable interior tomography in microscopic CT applications. The proposed LRICR algorithm outperforms the multi-resolution scout-reconstruction method and the TV minimization based reconstruction for interior tomography in microscopic CT.
High Efficiency Multi-shot Interleaved Spiral-In/Out Acquisition for High Resolution BOLD fMRI
Jung, Youngkyoo; Samsonov, Alexey A.; Liu, Thomas T.; Buracas, Giedrius T.
2012-01-01
Growing demand for high spatial resolution BOLD functional MRI faces a challenge of the spatial resolution vs. coverage or temporal resolution tradeoff, which can be addressed by methods that afford increased acquisition efficiency. Spiral acquisition trajectories have been shown to be superior to currently prevalent echo-planar imaging in terms of acquisition efficiency, and high spatial resolution can be achieved by employing multiple-shot spiral acquisition. The interleaved spiral in-out trajectory is preferred over spiral-in due to increased BOLD signal CNR and higher acquisition efficiency than that of spiral-out or non-interleaved spiral in/out trajectories (1), but to date applicability of the multi-shot interleaved spiral in-out for high spatial resolution imaging has not been studied. Herein we propose multi-shot interleaved spiral in-out acquisition and investigate its applicability for high spatial resolution BOLD fMRI. Images reconstructed from interleaved spiral-in and -out trajectories possess artifacts caused by differences in T2* decay, off-resonance and k-space errors associated with the two trajectories. We analyze the associated errors and demonstrate that application of conjugate phase reconstruction and spectral filtering can substantially mitigate these image artifacts. After applying these processing steps, the multishot interleaved spiral in-out pulse sequence yields high BOLD CNR images at in-plane resolution below 1x1 mm while preserving acceptable temporal resolution (4 s) and brain coverage (15 slices of 2 mm thickness). Moreover, this method yields sufficient BOLD CNR at 1.5 mm isotropic resolution for detection of activation in hippocampus associated with cognitive tasks (Stern memory task). The multi-shot interleaved spiral in-out acquisition is a promising technique for high spatial resolution BOLD fMRI applications. PMID:23023395
NASA Astrophysics Data System (ADS)
Singh, G.; Das, N. N.; Panda, R. K.; Mohanty, B.; Entekhabi, D.; Bhattacharya, B. K.
2016-12-01
Soil moisture status at high resolution (1-10 km) is vital for hydrological, agricultural and hydro-metrological applications. The NASA Soil Moisture Active Passive (SMAP) mission had potential to provide reliable soil moisture estimate at finer spatial resolutions (3 km and 9 km) at the global extent, but suffered a malfunction of its radar, consequently making the SMAP mission observations only from radiometer that are of coarse spatial resolution. At present, the availability of high-resolution soil moisture product is limited, especially in developing countries like India, which greatly depends on agriculture for sustaining a huge population. Therefore, an attempt has been made in the reported study to combine the C-band synthetic aperture radar (SAR) data from Radar Imaging Satellite (RISAT) of the Indian Space Research Organization (ISRO) with the SMAP mission L-band radiometer data to obtain high-resolution (1 km and 3 km) soil moisture estimates. In this study, a downscaling approach (Active-Passive Algorithm) implemented for the SMAP mission was used to disaggregate the SMAP radiometer brightness temperature (Tb) using the fine resolution SAR backscatter (σ0) from RISAT. The downscaled high-resolution Tb was then subjected to tau-omega model in conjunction with high-resolution ancillary data to retrieve soil moisture at 1 and 3 km scale. The retrieved high-resolution soil moisture estimates were then validated with ground based soil moisture measurement under different hydro-climatic regions of India. Initial results show tremendous potential and reasonable accuracy for the retrieved soil moisture at 1 km and 3 km. It is expected that ISRO will implement this approach to produce high-resolution soil moisture estimates for the Indian subcontinent.
Using high spectral resolution spectrophotometry to study broad mineral absorption features on Mars
NASA Technical Reports Server (NTRS)
Blaney, D. L.; Crisp, D.
1993-01-01
Traditionally telescopic measurements of mineralogic absorption features have been made using relatively low to moderate (R=30-300) spectral resolution. Mineralogic absorption features tend to be broad so high resolution spectroscopy (R greater than 10,000) does not provide significant additional compositional information. Low to moderate resolution spectroscopy allows an observer to obtain data over a wide wavelength range (hundreds to thousands of wavenumbers) compared to the several wavenumber intervals that are collected using high resolution spectrometers. However, spectrophotometry at high resolution has major advantages over lower resolution spectroscopy in situations that are applicable to studies of the Martian surface, i.e., at wavelengths where relatively weak surface absorption features and atmospheric gas absorption features both occur.
The effect of horizontal resolution on simulation quality in the Community Atmospheric Model, CAM5.1
Wehner, Michael F.; Reed, Kevin A.; Li, Fuyu; ...
2014-10-13
We present an analysis of version 5.1 of the Community Atmospheric Model (CAM5.1) at a high horizontal resolution. Intercomparison of this global model at approximately 0.25°, 1°, and 2° is presented for extreme daily precipitation as well as for a suite of seasonal mean fields. In general, extreme precipitation amounts are larger in high resolution than in lower-resolution configurations. In many but not all locations and/or seasons, extreme daily precipitation rates in the high-resolution configuration are higher and more realistic. The high-resolution configuration produces tropical cyclones up to category 5 on the Saffir-Simpson scale and a comparison to observations revealsmore » both realistic and unrealistic model behavior. In the absence of extensive model tuning at high resolution, simulation of many of the mean fields analyzed in this study is degraded compared to the tuned lower-resolution public released version of the model.« less
Recent applications of gas chromatography with high-resolution mass spectrometry.
Špánik, Ivan; Machyňáková, Andrea
2018-01-01
Gas chromatography coupled to high-resolution mass spectrometry is a powerful analytical method that combines excellent separation power of gas chromatography with improved identification based on an accurate mass measurement. These features designate gas chromatography with high-resolution mass spectrometry as the first choice for identification and structure elucidation of unknown volatile and semi-volatile organic compounds. Gas chromatography with high-resolution mass spectrometry quantitative analyses was previously focused on the determination of dioxins and related compounds using magnetic sector type analyzers, a standing requirement of many international standards. The introduction of a quadrupole high-resolution time-of-flight mass analyzer broadened interest in this method and novel applications were developed, especially for multi-target screening purposes. This review is focused on the development and the most interesting applications of gas chromatography coupled to high-resolution mass spectrometry towards analysis of environmental matrices, biological fluids, and food safety since 2010. The main attention is paid to various approaches and applications of gas chromatography coupled to high-resolution mass spectrometry for non-target screening to identify contaminants and to characterize the chemical composition of environmental, food, and biological samples. The most interesting quantitative applications, where a significant contribution of gas chromatography with high-resolution mass spectrometry over the currently used methods is expected, will be discussed as well. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A compact high-resolution 3-D imaging spectrometer for discovering Oases on Mars
Ge, J.; Ren, D.; Lunine, J.I.; Brown, R.H.; Yelle, R.V.; Soderblom, L.A.; ,
2002-01-01
A new design for a very lightweight, very high throughput reflectance sectrometer enabled by two new technologies being developed is presented. These new technologies include integral field unit optics to enable simultaneous imaging and spectroscopy at high spatial resolution with an infrared (IR) array, and silicon grisms to enable compact and high-resolution spectroscopy.
Crawshaw, Benjamin P; Russ, Andrew J; Stein, Sharon L; Reynolds, Harry L; Marderstein, Eric L; Delaney, Conor P; Champagne, Bradley J
2015-01-01
High-resolution anoscopy has been shown to improve identification of anal intraepithelial neoplasia but a reduction in progression to anal squamous-cell cancer has not been substantiated when serial high-resolution anoscopy is compared with traditional expectant management. The aim of this study was to compare high-resolution anoscopy versus expectant management for the surveillance of anal intraepithelial neoplasia and the prevention of anal cancer. This is a retrospective review of all patients who presented with anal squamous dysplasia, positive anal Pap smears, or anal squamous-cell cancer from 2007 to 2013. This study was performed in the colorectal department of a university-affiliated, tertiary care hospital. Included patients had biopsy-proven anal intraepithelial neoplasia from 2007 to 2013. Patients were treated with high-resolution anoscopy with ablation or standard anoscopy with ablation. Both groups were treated with imiquimod and followed every 6 months indefinitely. The incidence of anal squamous-cell cancer in each group was the primary end point. From 2007 to 2013, 424 patients with anal squamous dysplasia were seen in the clinic (high-resolution anoscopy, 220; expectant management, 204). Three patients (high-resolution anoscopy, 1; expectant management, 2) progressed to anal squamous-cell cancer; 2 were noncompliant with follow-up and with HIV treatment, and the third was allergic to imiquimod and refused to take topical 5-fluorouracil. The 5-year progression rate was 6.0% (95% CI, 1.5-24.6) for expectant management and 4.5% (95% CI, 0.7-30.8) for high-resolution anoscopy (p = 0.37). This was a retrospective review. There is potential for selection and referral bias. Because of the rarity of the outcome, the study may be underpowered. Patients with squamous-cell dysplasia followed with expectant management or high-resolution anoscopy rarely develop squamous-cell cancer if they are compliant with the protocol. The cost, morbidity, and value of high-resolution anoscopy should be further evaluated in lieu of these findings.
NASA Astrophysics Data System (ADS)
Ba, Yu Tao; xian Liu, Bao; Sun, Feng; Wang, Li hua; Tang, Yu jia; Zhang, Da wei
2017-04-01
High-resolution mapping of PM2.5 is the prerequisite for precise analytics and subsequent anti-pollution interventions. Considering the large variances of particulate distribution, urban-scale mapping is challenging either with ground-based fixed stations, with satellites or via models. In this study, a dynamic fusion method between high-density sensor network and MODIS Aerosol Optical Depth (AOD) was introduced. The sensor network was deployed in Beijing ( > 1000 fixed monitors across 16000 km2 area) to provide raw observations with high temporal resolution (sampling interval < 1 hour), high spatial resolution in flat areas ( < 1 km), and low spatial resolution in mountainous areas ( > 5 km). The MODIS AOD was calibrated to provide distribution map with low temporal resolution (daily) and moderate spatial resolution ( = 3 km). By encoding the data quality and defects (e.g. could, reflectance, abnormal), a hybrid interpolation procedure with cross-validation generated PM2.5 distribution with both high temporal and spatial resolution. Several no-pollutant and high-pollution periods were tested to validate the proposed fusion method for capturing the instantaneous patterns of PM2.5 emission.
NASA Technical Reports Server (NTRS)
Desai, U. D.; Orwig, Larry E.
1988-01-01
In the areas of high spatial resolution, the evaluation of a hard X-ray detector with 65 micron spatial resolution for operation in the energy range from 30 to 400 keV is proposed. The basic detector is a thick large-area scintillator faceplate, composed of a matrix of high-density scintillating glass fibers, attached to a proximity type image intensifier tube with a resistive-anode digital readout system. Such a detector, combined with a coded-aperture mask, would be ideal for use as a modest-sized hard X-ray imaging instrument up to X-ray energies as high as several hundred keV. As an integral part of this study it was also proposed that several techniques be critically evaluated for X-ray image coding which could be used with this detector. In the area of high spectral resolution, it is proposed to evaluate two different types of detectors for use as X-ray spectrometers for solar flares: planar silicon detectors and high-purity germanium detectors (HPGe). Instruments utilizing these high-spatial-resolution detectors for hard X-ray imaging measurements from 30 to 400 keV and high-spectral-resolution detectors for measurements over a similar energy range would be ideally suited for making crucial solar flare observations during the upcoming maximum in the solar cycle.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Williams, Stuart S; Samulski, Edward; Lopez, Renee
2010-01-01
ABSTRACT. Described herein is the development and investigation of PFPE-based elastomers for high resolution replica molding applications. The modulus of the elastomeric materials was increased through synthetic and additive approaches while maintaining relatively low surface energies (<25 mN/m). Using practically relevant large area master templates, we show that the resolution of the molds is strongly dependant upon the elastomeric mold modulus. A composite mold approach was used to form flexible molds out of stiff, high modulus materials that allow for replication of sub-20 nm post structures. Sub-100 nm line grating master templates, formed using e-beam lithography, were used to determinemore » the experimental stability of the molding materials. It was observed that as the feature spacing decreased, high modulus composite molds were able to effectively replicate the nano-grating structures without cracking or tear-out defects that typically occur with high modulus elastomers.« less
SPARTAN II: An Instructional High Resolution Land Combat Model
1993-03-01
93M-09 SPARTAN II: AN INSTRUCTIONAL HIGH RESOLUTION LAND COMBAT MODEL THESIS DWquALfl’ 4 Presented to the Faculty of the School of Engineering of the...ADVISOR NAJ Edward Negrelli/ENS REALDER MAJ Bruce Marl an/MA LD1 { The goal of this thesis was to improve SPARTAN, a high resolution land combat model...should serve as a useful tool for learning about the advantages and disadvantages of high resolution combat modeling. I wish to thank I4AJ Edward
High-Resolution Array with Prony, MUSIC, and ESPRIT Algorithms
1992-08-25
N avalI Research La bora tory AD-A255 514 Washington, DC 20375-5320 NRL/FR/5324-92-9397 High-resolution Array with Prony, music , and ESPRIT...unlimited t"orm n pprovoiREPORT DOCUMENTATION PAGE OMB. o 0 104 0188 4. TITLE AND SUBTITLE S. FUNDING NUMBERS High-resolution Array with Prony. MUSIC . and...the array high-resolution properties of three algorithms: the Prony algo- rithm, the MUSIC algorithm, and the ESPRIT algorithm. MUSIC has been much
Luo, Y.; Xia, J.; Miller, R.D.; Liu, J.; Xu, Y.; Liu, Q.
2008-01-01
Multichannel Analysis of Surface Waves (MASW) analysis is an efficient tool to obtain the vertical shear-wave profile. One of the key steps in the MASW method is to generate an image of dispersive energy in the frequency-velocity domain, so dispersion curves can be determined by picking peaks of dispersion energy. In this paper, we image Rayleigh-wave dispersive energy and separate multimodes from a multichannel record by high-resolution linear Radon transform (LRT). We first introduce Rayleigh-wave dispersive energy imaging by high-resolution LRT. We then show the process of Rayleigh-wave mode separation. Results of synthetic and real-world examples demonstrate that (1) compared with slant stacking algorithm, high-resolution LRT can improve the resolution of images of dispersion energy by more than 50% (2) high-resolution LRT can successfully separate multimode dispersive energy of Rayleigh waves with high resolution; and (3) multimode separation and reconstruction expand frequency ranges of higher mode dispersive energy, which not only increases the investigation depth but also provides a means to accurately determine cut-off frequencies.
High resolution surface plasmon microscopy for cell imaging
NASA Astrophysics Data System (ADS)
Argoul, F.; Monier, K.; Roland, T.; Elezgaray, J.; Berguiga, L.
2010-04-01
We introduce a new non-labeling high resolution microscopy method for cellular imaging. This method called SSPM (Scanning Surface Plasmon Microscopy) pushes down the resolution limit of surface plasmon resonance imaging (SPRi) to sub-micronic scales. High resolution SPRi is obtained by the surface plasmon lauching with a high numerical aperture objective lens. The advantages of SPPM compared to other high resolution SPRi's rely on three aspects; (i) the interferometric detection of the back reflected light after plasmon excitation, (ii) the twodimensional scanning of the sample for image reconstruction, (iii) the radial polarization of light, enhancing both resolution and sensitivity. This microscope can afford a lateral resolution of - 150 nm in liquid environment and - 200 nm in air. We present in this paper images of IMR90 fibroblasts obtained with SSPM in dried environment. Internal compartments such as nucleus, nucleolus, mitochondria, cellular and nuclear membrane can be recognized without labelling. We propose an interpretation of the ability of SSPM to reveal high index contrast zones by a local decomposition of the V (Z) function describing the response of the SSPM.
A novel ToF-SIMS operation mode for sub 100 nm lateral resolution: Application and performance.
Kubicek, Markus; Holzlechner, Gerald; Opitz, Alexander K; Larisegger, Silvia; Hutter, Herbert; Fleig, Jürgen
2014-01-15
A novel operation mode for time of flight-secondary ion mass spectrometry (ToF-SIMS) is described for a TOF.SIMS 5 instrument with a Bi-ion gun. It features sub 100 nm lateral resolution, adjustable primary ion currents and the possibility to measure with high lateral resolution as well as high mass resolution. The adjustment and performance of the novel operation mode are described and compared to established ToF-SIMS operation modes. Several examples of application featuring novel scientific results show the capabilities of the operation mode in terms of lateral resolution, accuracy of isotope analysis of oxygen, and combination of high lateral and mass resolution. The relationship between high lateral resolution and operation of SIMS in static mode is discussed.
Klein, Isabelle F; Lavallée, Philippa C; Mazighi, Mikael; Schouman-Claeys, Elisabeth; Labreuche, Julien; Amarenco, Pierre
2010-07-01
Pontine infarction is most often related to basilar artery atherosclerosis when the lesion abuts on the basal surface (paramedian pontine infarction), whereas small medial pontine lesion is usually attributed to small vessel lipohyalinosis. A previous study has found that high-resolution MRI can detect basilar atherosclerotic plaques in up to 70% of patient with paramedian pontine infarction, even in patients with normal angiograms, but none has evaluated the presence of basilar artery plaque by high-resolution MRI in patients with small medial pontine lesion in the medial part of the pons. Consecutive patients with pontine infarction underwent basilar angiography using time-of-flight and contrast-enhanced 3-dimensional MR angiography to assess the presence of basilar artery stenosis and high-resolution MRI to assess the presence of atherosclerotic plaque. Basilar artery angiogram was scored as "normal," "irregular," or "stenosed" >or=30%" and basilar artery by high-resolution MRI was scored as "normal" or "presence of plaque." Medial pontine infarcts were divided into paramedian pontine infarction and small medial pontine lesion groups. Forty-one patients with pontine infarction were included, 26 with paramedian pontine infarction and 15 with small medial pontine lesion. High-resolution MRI detected basilar artery atherosclerosis in 42% of patients with a pontine infarction and normal basilar angiograms. Among patients with paramedian pontine infarction, 65% had normal basilar angiograms but 77% had basilar artery atherosclerosis detected on high-resolution MRI. Among patients with small medial pontine lesion, 46% had normal basilar angiograms but 73% had basilar artery plaques detected on by high-resolution MRI. This study suggests that medial pontine lacunes may be due to a penetrating artery disease secondary to basilar artery atherosclerosis. High-resolution MRI could help precise stroke subtyping.
Image super-resolution via sparse representation.
Yang, Jianchao; Wright, John; Huang, Thomas S; Ma, Yi
2010-11-01
This paper presents a new approach to single-image super-resolution, based on sparse signal representation. Research on image statistics suggests that image patches can be well-represented as a sparse linear combination of elements from an appropriately chosen over-complete dictionary. Inspired by this observation, we seek a sparse representation for each patch of the low-resolution input, and then use the coefficients of this representation to generate the high-resolution output. Theoretical results from compressed sensing suggest that under mild conditions, the sparse representation can be correctly recovered from the downsampled signals. By jointly training two dictionaries for the low- and high-resolution image patches, we can enforce the similarity of sparse representations between the low resolution and high resolution image patch pair with respect to their own dictionaries. Therefore, the sparse representation of a low resolution image patch can be applied with the high resolution image patch dictionary to generate a high resolution image patch. The learned dictionary pair is a more compact representation of the patch pairs, compared to previous approaches, which simply sample a large amount of image patch pairs, reducing the computational cost substantially. The effectiveness of such a sparsity prior is demonstrated for both general image super-resolution and the special case of face hallucination. In both cases, our algorithm generates high-resolution images that are competitive or even superior in quality to images produced by other similar SR methods. In addition, the local sparse modeling of our approach is naturally robust to noise, and therefore the proposed algorithm can handle super-resolution with noisy inputs in a more unified framework.
Liu, Danzhou; Hua, Kien A; Sugaya, Kiminobu
2008-09-01
With the advances in medical imaging devices, large volumes of high-resolution 3-D medical image data have been produced. These high-resolution 3-D data are very large in size, and severely stress storage systems and networks. Most existing Internet-based 3-D medical image interactive applications therefore deal with only low- or medium-resolution image data. While it is possible to download the whole 3-D high-resolution image data from the server and perform the image visualization and analysis at the client site, such an alternative is infeasible when the high-resolution data are very large, and many users concurrently access the server. In this paper, we propose a novel framework for Internet-based interactive applications of high-resolution 3-D medical image data. Specifically, we first partition the whole 3-D data into buckets, remove the duplicate buckets, and then, compress each bucket separately. We also propose an index structure for these buckets to efficiently support typical queries such as 3-D slicer and region of interest, and only the relevant buckets are transmitted instead of the whole high-resolution 3-D medical image data. Furthermore, in order to better support concurrent accesses and to improve the average response time, we also propose techniques for efficient query processing, incremental transmission, and client sharing. Our experimental study in simulated and realistic environments indicates that the proposed framework can significantly reduce storage and communication requirements, and can enable real-time interaction with remote high-resolution 3-D medical image data for many concurrent users.
High resolution land surface geophysical parameters estimation from ALOS PALSAR data
USDA-ARS?s Scientific Manuscript database
High resolution land surface geophysical products, such as soil moisture, surface roughness and vegetation water content, are essential for a variety of applications ranging from water management to regional climate predictions. In India high resolution geophysical products, in particular soil moist...
Automatic optimization high-speed high-resolution OCT retinal imaging at 1μm
NASA Astrophysics Data System (ADS)
Cua, Michelle; Liu, Xiyun; Miao, Dongkai; Lee, Sujin; Lee, Sieun; Bonora, Stefano; Zawadzki, Robert J.; Mackenzie, Paul J.; Jian, Yifan; Sarunic, Marinko V.
2015-03-01
High-resolution OCT retinal imaging is important in providing visualization of various retinal structures to aid researchers in better understanding the pathogenesis of vision-robbing diseases. However, conventional optical coherence tomography (OCT) systems have a trade-off between lateral resolution and depth-of-focus. In this report, we present the development of a focus-stacking optical coherence tomography (OCT) system with automatic optimization for high-resolution, extended-focal-range clinical retinal imaging. A variable-focus liquid lens was added to correct for de-focus in real-time. A GPU-accelerated segmentation and optimization was used to provide real-time layer-specific enface visualization as well as depth-specific focus adjustment. After optimization, multiple volumes focused at different depths were acquired, registered, and stitched together to yield a single, high-resolution focus-stacked dataset. Using this system, we show high-resolution images of the ONH, from which we extracted clinically-relevant parameters such as the nerve fiber layer thickness and lamina cribrosa microarchitecture.
Christopher Daly; Jonathan W. Smith; Joseph I. Smith; Robert B. McKane
2007-01-01
High-quality daily meteorological data at high spatial resolution are essential for a variety of hydrologic and ecological modeling applications that support environmental risk assessments and decisionmaking. This paper describes the development. application. and assessment of methods to construct daily high resolution (~50-m cell size) meteorological grids for the...
NASA Astrophysics Data System (ADS)
Cooper, R. J.; Amman, M.; Vetter, K.
2018-04-01
High-resolution gamma-ray spectrometers are required for applications in nuclear safeguards, emergency response, and fundamental nuclear physics. To overcome one of the shortcomings of conventional High Purity Germanium (HPGe) detectors, we have developed a prototype device capable of achieving high event throughput and high energy resolution at very high count rates. This device, the design of which we have previously reported on, features a planar HPGe crystal with a reduced-capacitance strip electrode geometry. This design is intended to provide good energy resolution at the short shaping or digital filter times that are required for high rate operation and which are enabled by the fast charge collection afforded by the planar geometry crystal. In this work, we report on the initial performance of the system at count rates up to and including two million counts per second.
Single image super-resolution via an iterative reproducing kernel Hilbert space method.
Deng, Liang-Jian; Guo, Weihong; Huang, Ting-Zhu
2016-11-01
Image super-resolution, a process to enhance image resolution, has important applications in satellite imaging, high definition television, medical imaging, etc. Many existing approaches use multiple low-resolution images to recover one high-resolution image. In this paper, we present an iterative scheme to solve single image super-resolution problems. It recovers a high quality high-resolution image from solely one low-resolution image without using a training data set. We solve the problem from image intensity function estimation perspective and assume the image contains smooth and edge components. We model the smooth components of an image using a thin-plate reproducing kernel Hilbert space (RKHS) and the edges using approximated Heaviside functions. The proposed method is applied to image patches, aiming to reduce computation and storage. Visual and quantitative comparisons with some competitive approaches show the effectiveness of the proposed method.
2007-03-01
time. This is a very powerful tool in determining fine spatial resolution , as boundary conditions are not only updated at every timestep, but the ...HIGH RESOLUTION MESOSCALE WEATHER DATA IMPROVEMENT TO SPATIAL EFFECTS FOR DOSE-RATE CONTOUR PLOT PREDICTIONS THESIS Christopher P...11 1 HIGH RESOLUTION MESOSCALE WEATHER DATA IMPROVEMENT TO SPATIAL EFFECTS FOR DOSE-RATE CONTOUR PLOT
NASA Astrophysics Data System (ADS)
Yin, Leilei; Chen, Ying-Chieh; Gelb, Jeff; Stevenson, Darren M.; Braun, Paul A.
2010-09-01
High resolution x-ray computed tomography is a powerful non-destructive 3-D imaging method. It can offer superior resolution on objects that are opaque or low contrast for optical microscopy. Synchrotron based x-ray computed tomography systems have been available for scientific research, but remain difficult to access for broader users. This work introduces a lab-based high-resolution x-ray nanotomography system with 50nm resolution in absorption and Zernike phase contrast modes. Using this system, we have demonstrated high quality 3-D images of polymerized photonic crystals which have been analyzed for band gap structures. The isotropic volumetric data shows excellent consistency with other characterization results.
Sheng, Duo; Lai, Hsiu-Fan; Chan, Sheng-Min; Hong, Min-Rong
2015-02-13
An all-digital on-chip delay sensor (OCDS) circuit with high delay-measurement resolution and low supply-voltage sensitivity for efficient detection and diagnosis in high-performance electronic system applications is presented. Based on the proposed delay measurement scheme, the quantization resolution of the proposed OCDS can be reduced to several picoseconds. Additionally, the proposed cascade-stage delay measurement circuit can enhance immunity to supply-voltage variations of the delay measurement resolution without extra self-biasing or calibration circuits. Simulation results show that the delay measurement resolution can be improved to 1.2 ps; the average delay resolution variation is 0.55% with supply-voltage variations of ±10%. Moreover, the proposed delay sensor can be implemented in an all-digital manner, making it very suitable for high-performance electronic system applications as well as system-level integration.
Resolution Enhancement of Hyperion Hyperspectral Data using Ikonos Multispectral Data
2007-09-01
spatial - resolution hyperspectral image to produce a sharpened product. The result is a product that has the spectral properties of the ...multispectral sensors. In this work, we examine the benefits of combining data from high- spatial - resolution , low- spectral - resolution spectral imaging...sensors with data obtained from high- spectral - resolution , low- spatial - resolution spectral imaging sensors.
Kang, Jeon Woong; So, Peter T. C.; Dasari, Ramachandra R.; Lim, Dong-Kwon
2015-01-01
We report a method to achieve high speed and high resolution live cell Raman images using small spherical gold nanoparticles with highly narrow intra-nanogap structures responding to NIR excitation (785 nm) and high-speed confocal Raman microscopy. The three different Raman-active molecules placed in the narrow intra-nanogap showed a strong and uniform Raman intensity in solution even under transient exposure time (10 ms) and low input power of incident laser (200 μW), which lead to obtain high-resolution single cell image within 30 s without inducing significant cell damage. The high resolution Raman image showed the distributions of gold nanoparticles for their targeted sites such as cytoplasm, mitochondria, or nucleus. The high speed Raman-based live cell imaging allowed us to monitor rapidly changing cell morphologies during cell death induced by the addition of highly toxic KCN solution to cells. These results strongly suggest that the use of SERS-active nanoparticle can greatly improve the current temporal resolution and image quality of Raman-based cell images enough to obtain the detailed cell dynamics and/or the responses of cells to potential drug molecules. PMID:25646716
Liss, K D; Royer, A; Tschentscher, T; Suortti, P; Williams, A P
1998-03-01
High-energy X-rav diffraction by means of triple-crystal techniques is a powerful tool for investigating dislocations and strain in bulk materials. Radiation with an energy typically higher than 80 keV combines the advantage of low attenuation with high resolution at large momentum transfers. The triple-crystal diffractometer at the High Energy Beamline of the European Synchrotron Radiation Facility is described. It is shown how the transverse and longitudinal resolution depend on the choice of the crystal reflection, and how the orientation of a reciprocal-lattice distortion in an investigated sample towards the resolution element of the instrument can play an important role. This effect is demonstrated on a single crystal of silicon where a layer of macro pores reveals satellites around the Bragg reflection. The resulting longitudinal distortion can be investigated using the high transverse resolution of the instrument when choosing an appropriate reflection.
Beyond Population Distribution: Enhancing Sociocultural Resolution from Remote Sensing
NASA Astrophysics Data System (ADS)
Bhaduri, B. L.; Rose, A.
2017-12-01
At Oak Ridge National Laboratory, since late 1990s, we have focused on developing high resolution population distribution and dynamics data from local to global scales. Increasing resolutions of geographic data has been mirrored by population data sets developed across the community. However, attempts to increase temporal and sociocultural resolutions have been limited given the lack of high resolution data on human settlements and activities. While recent advancements in moderate to high resolution earth observation have led to better physiographic data, the approach of exploiting very high resolution (sub-meter resolution) imagery has also proven useful for generating accurate human settlement maps. It allows potential (social and vulnerability) characterization of population from settlement structures by exploiting image texture and spectral features. Our recent research utilizing machine learning and geocomputation has not only validated "poverty mapping from imagery" hypothesis, but has delineated a new paradigm of rapid analysis of high resolution imagery to enhance such "neighborhood" mapping techniques. Such progress in GIScience is allowing us to move towards the goal of creating a global foundation level database for impervious surfaces and "neighborhoods," and holds tremendous promise for key applications focusing on sustainable development including many social science applications.
NASA Technical Reports Server (NTRS)
Ziemke, Robert A.
1990-01-01
The objective of the High Resolution, High Frame Rate Video Technology (HHVT) development effort is to provide technology advancements to remove constraints on the amount of high speed, detailed optical data recorded and transmitted for microgravity science and application experiments. These advancements will enable the development of video systems capable of high resolution, high frame rate video data recording, processing, and transmission. Techniques such as multichannel image scan, video parameter tradeoff, and the use of dual recording media were identified as methods of making the most efficient use of the near-term technology.
Conductive Atomic Force Microscopy | Materials Science | NREL
electrical measurement techniques is the high spatial resolution. For example, C-AFM measurements on : High-resolution image of a sample semiconductor device; the image shows white puff-like clusters on a dark background and was obtained using atomic force microscopy. Bottom: High-resolution image of the
SALT high resolution spectroscopy of GX339-4 in outburst
NASA Astrophysics Data System (ADS)
Buckley, D. A. H.; Aydi, E.; Kotze, M. M.; Gandhi, P.; Altamirano, D.; Charles, P. A.; Russell, D.
2017-10-01
High resolution (R = 15,000) spectroscopy of the current outbursting black hole transient GX339-4 (ATel #10797) was obtained with the SALT High Resolution Spectrograph (HRS; Crause et al. 2014, Proc SPIE, 91476) on 2017-09-29 starting at 17:28 UTC, during evening twilight.
Application and evaluation of high-resolution WRF-CMAQ with simple urban parameterization.
The 2-way coupled WRF-CMAQ meteorology and air quality modeling system is evaluated for high-resolution applications by comparing to a regional air quality field study (Discover-AQ). The model was modified to better account for the effects of urban environments. High-resolution...
USDA-ARS?s Scientific Manuscript database
Thermal and multispectral remote sensing data from low-altitude aircraft can provide high spatial resolution necessary for sub-field (= 10 m) and plant canopy (= 1 m) scale evapotranspiration (ET) monitoring. In this study, high resolution aircraft sub-meter scale thermal infrared and multispectral...
Application and evaluation of high-resolution WRF-CMAQ with simple urban parameterization
The 2-way coupled WRF-CMAQ meteorology and air quality modeling system is evaluated for high-resolution applications by comparing to a regional air quality field study (Discover-AQ). The model was modified to better account for the effects of urban environments. High-resolution...
NASA Astrophysics Data System (ADS)
Mondal, Sudip; Hegarty, Evan; Martin, Chris; Gökçe, Sertan Kutal; Ghorashian, Navid; Ben-Yakar, Adela
2016-10-01
Next generation drug screening could benefit greatly from in vivo studies, using small animal models such as Caenorhabditis elegans for hit identification and lead optimization. Current in vivo assays can operate either at low throughput with high resolution or with low resolution at high throughput. To enable both high-throughput and high-resolution imaging of C. elegans, we developed an automated microfluidic platform. This platform can image 15 z-stacks of ~4,000 C. elegans from 96 different populations using a large-scale chip with a micron resolution in 16 min. Using this platform, we screened ~100,000 animals of the poly-glutamine aggregation model on 25 chips. We tested the efficacy of ~1,000 FDA-approved drugs in improving the aggregation phenotype of the model and identified four confirmed hits. This robust platform now enables high-content screening of various C. elegans disease models at the speed and cost of in vitro cell-based assays.
High efficiency multishot interleaved spiral-in/out: acquisition for high-resolution BOLD fMRI.
Jung, Youngkyoo; Samsonov, Alexey A; Liu, Thomas T; Buracas, Giedrius T
2013-08-01
Growing demand for high spatial resolution blood oxygenation level dependent (BOLD) functional magnetic resonance imaging faces a challenge of the spatial resolution versus coverage or temporal resolution tradeoff, which can be addressed by methods that afford increased acquisition efficiency. Spiral acquisition trajectories have been shown to be superior to currently prevalent echo-planar imaging in terms of acquisition efficiency, and high spatial resolution can be achieved by employing multiple-shot spiral acquisition. The interleaved spiral in/out trajectory is preferred over spiral-in due to increased BOLD signal contrast-to-noise ratio (CNR) and higher acquisition efficiency than that of spiral-out or noninterleaved spiral in/out trajectories (Law & Glover. Magn Reson Med 2009; 62:829-834.), but to date applicability of the multishot interleaved spiral in/out for high spatial resolution imaging has not been studied. Herein we propose multishot interleaved spiral in/out acquisition and investigate its applicability for high spatial resolution BOLD functional magnetic resonance imaging. Images reconstructed from interleaved spiral-in and -out trajectories possess artifacts caused by differences in T2 decay, off-resonance, and k-space errors associated with the two trajectories. We analyze the associated errors and demonstrate that application of conjugate phase reconstruction and spectral filtering can substantially mitigate these image artifacts. After applying these processing steps, the multishot interleaved spiral in/out pulse sequence yields high BOLD CNR images at in-plane resolution below 1 × 1 mm while preserving acceptable temporal resolution (4 s) and brain coverage (15 slices of 2 mm thickness). Moreover, this method yields sufficient BOLD CNR at 1.5 mm isotropic resolution for detection of activation in hippocampus associated with cognitive tasks (Stern memory task). The multishot interleaved spiral in/out acquisition is a promising technique for high spatial resolution BOLD functional magnetic resonance imaging applications. © 2012 Wiley Periodicals, Inc.
Evaluating an image-fusion algorithm with synthetic-image-generation tools
NASA Astrophysics Data System (ADS)
Gross, Harry N.; Schott, John R.
1996-06-01
An algorithm that combines spectral mixing and nonlinear optimization is used to fuse multiresolution images. Image fusion merges images of different spatial and spectral resolutions to create a high spatial resolution multispectral combination. High spectral resolution allows identification of materials in the scene, while high spatial resolution locates those materials. In this algorithm, conventional spectral mixing estimates the percentage of each material (called endmembers) within each low resolution pixel. Three spectral mixing models are compared; unconstrained, partially constrained, and fully constrained. In the partially constrained application, the endmember fractions are required to sum to one. In the fully constrained application, all fractions are additionally required to lie between zero and one. While negative fractions seem inappropriate, they can arise from random spectral realizations of the materials. In the second part of the algorithm, the low resolution fractions are used as inputs to a constrained nonlinear optimization that calculates the endmember fractions for the high resolution pixels. The constraints mirror the low resolution constraints and maintain consistency with the low resolution fraction results. The algorithm can use one or more higher resolution sharpening images to locate the endmembers to high spatial accuracy. The algorithm was evaluated with synthetic image generation (SIG) tools. A SIG developed image can be used to control the various error sources that are likely to impair the algorithm performance. These error sources include atmospheric effects, mismodeled spectral endmembers, and variability in topography and illumination. By controlling the introduction of these errors, the robustness of the algorithm can be studied and improved upon. The motivation for this research is to take advantage of the next generation of multi/hyperspectral sensors. Although the hyperspectral images will be of modest to low resolution, fusing them with high resolution sharpening images will produce a higher spatial resolution land cover or material map.
B. W. Butler; N. S. Wagenbrenner; J. M. Forthofer; B. K. Lamb; K. S. Shannon; D. Finn; R. M. Eckman; K. Clawson; L. Bradshaw; P. Sopko; S. Beard; D. Jimenez; C. Wold; M. Vosburgh
2015-01-01
A number of numerical wind flow models have been developed for simulating wind flow at relatively fine spatial resolutions (e.g., 100 m); however, there are very limited observational data available for evaluating these high-resolution models. This study presents high-resolution surface wind data sets collected from an isolated mountain and a steep river canyon. The...
John T. Abatzoglou; Solomon Z. Dobrowski; Sean A. Parks; Katherine C. Hegewisch
2018-01-01
We present TerraClimate, a dataset of high-spatial resolution (1/24°, ~4-km) monthly climate and climatic water balance for global terrestrial surfaces from 1958â2015. TerraClimate uses climatically aided interpolation, combining high-spatial resolution climatological normals from the WorldClim dataset, with coarser resolution time varying (i.e., monthly) data from...
NASA Astrophysics Data System (ADS)
Suárez, F.; Aravena, J. E.; Hausner, M. B.; Childress, A. E.; Tyler, S. W.
2011-03-01
In shallow thermohaline-driven lakes it is important to measure temperature on fine spatial and temporal scales to detect stratification or different hydrodynamic regimes. Raman spectra distributed temperature sensing (DTS) is an approach available to provide high spatial and temporal temperature resolution. A vertical high-resolution DTS system was constructed to overcome the problems of typical methods used in the past, i.e., without disturbing the water column, and with resistance to corrosive environments. This paper describes a method to quantitatively assess accuracy, precision and other limitations of DTS systems to fully utilize the capacity of this technology, with a focus on vertical high-resolution to measure temperatures in shallow thermohaline environments. It also presents a new method to manually calibrate temperatures along the optical fiber achieving significant improved resolution. The vertical high-resolution DTS system is used to monitor the thermal behavior of a salt-gradient solar pond, which is an engineered shallow thermohaline system that allows collection and storage of solar energy for a long period of time. The vertical high-resolution DTS system monitors the temperature profile each 1.1 cm vertically and in time averages as small as 10 s. Temperature resolution as low as 0.035 °C is obtained when the data are collected at 5-min intervals.
Zhang, Qi; Yang, Xiong; Hu, Qinglei; Bai, Ke; Yin, Fangfang; Li, Ning; Gang, Yadong; Wang, Xiaojun; Zeng, Shaoqun
2017-01-01
To resolve fine structures of biological systems like neurons, it is required to realize microscopic imaging with sufficient spatial resolution in three dimensional systems. With regular optical imaging systems, high lateral resolution is accessible while high axial resolution is hard to achieve in a large volume. We introduce an imaging system for high 3D resolution fluorescence imaging of large volume tissues. Selective plane illumination was adopted to provide high axial resolution. A scientific CMOS working in sub-array mode kept the imaging area in the sample surface, which restrained the adverse effect of aberrations caused by inclined illumination. Plastic embedding and precise mechanical sectioning extended the axial range and eliminated distortion during the whole imaging process. The combination of these techniques enabled 3D high resolution imaging of large tissues. Fluorescent bead imaging showed resolutions of 0.59 μm, 0.47μm, and 0.59 μm in the x, y, and z directions, respectively. Data acquired from the volume sample of brain tissue demonstrated the applicability of this imaging system. Imaging of different depths showed uniform performance where details could be recognized in either the near-soma area or terminal area, and fine structures of neurons could be seen in both the xy and xz sections. PMID:29296503
Enhancing SMAP Soil Moisture Retrievals via Superresolution Techniques
NASA Astrophysics Data System (ADS)
Beale, K. D.; Ebtehaj, A. M.; Romberg, J. K.; Bras, R. L.
2017-12-01
Soil moisture is a key state variable that modulates land-atmosphere interactions and its high-resolution global scale estimates are essential for improved weather forecasting, drought prediction, crop management, and the safety of troop mobility. Currently, NASA's Soil Moisture Active/Passive (SMAP) satellite provides a global picture of soil moisture variability at a resolution of 36 km, which is prohibitive for some hydrologic applications. The goal of this research is to enhance the resolution of SMAP passive microwave retrievals by a factor of 2 to 4 using modern superresolution techniques that rely on the knowledge of high-resolution land surface models. In this work, we explore several super-resolution techniques including an empirical dictionary method, a learned dictionary method, and a three-layer convolutional neural network. Using a year of global high-resolution land surface model simulations as training set, we found that we are able to produce high-resolution soil moisture maps that outperform the original low-resolution observations both qualitatively and quantitatively. In particular, on a patch-by-patch basis we are able to produce estimates of high-resolution soil moisture maps that improve on the original low-resolution patches by on average 6% in terms of mean-squared error, and 14% in terms of the structural similarity index.
High-resolution dynamic 31 P-MRSI using a low-rank tensor model.
Ma, Chao; Clifford, Bryan; Liu, Yuchi; Gu, Yuning; Lam, Fan; Yu, Xin; Liang, Zhi-Pei
2017-08-01
To develop a rapid 31 P-MRSI method with high spatiospectral resolution using low-rank tensor-based data acquisition and image reconstruction. The multidimensional image function of 31 P-MRSI is represented by a low-rank tensor to capture the spatial-spectral-temporal correlations of data. A hybrid data acquisition scheme is used for sparse sampling, which consists of a set of "training" data with limited k-space coverage to capture the subspace structure of the image function, and a set of sparsely sampled "imaging" data for high-resolution image reconstruction. An explicit subspace pursuit approach is used for image reconstruction, which estimates the bases of the subspace from the "training" data and then reconstructs a high-resolution image function from the "imaging" data. We have validated the feasibility of the proposed method using phantom and in vivo studies on a 3T whole-body scanner and a 9.4T preclinical scanner. The proposed method produced high-resolution static 31 P-MRSI images (i.e., 6.9 × 6.9 × 10 mm 3 nominal resolution in a 15-min acquisition at 3T) and high-resolution, high-frame-rate dynamic 31 P-MRSI images (i.e., 1.5 × 1.5 × 1.6 mm 3 nominal resolution, 30 s/frame at 9.4T). Dynamic spatiospectral variations of 31 P-MRSI signals can be efficiently represented by a low-rank tensor. Exploiting this mathematical structure for data acquisition and image reconstruction can lead to fast 31 P-MRSI with high resolution, frame-rate, and SNR. Magn Reson Med 78:419-428, 2017. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.
Chang, Hing-Chiu; Sundman, Mark; Petit, Laurent; Guhaniyogi, Shayan; Chu, Mei-Lan; Petty, Christopher; Song, Allen W.; Chen, Nan-kuei
2015-01-01
The advantages of high-resolution diffusion tensor imaging (DTI) have been demonstrated in a recent post-mortem human brain study (Miller et al., NeuroImage 2011;57(1):167–181), showing that white matter fiber tracts can be much more accurately detected in data at submillimeter isotropic resolution. To our knowledge, in vivo human brain DTI at submillimeter isotropic resolution has not been routinely achieved yet because of the difficulty in simultaneously achieving high resolution and high signal-to-noise ratio (SNR) in DTI scans. Here we report a 3D multi-slab interleaved EPI acquisition integrated with multiplexed sensitivity encoded (MUSE) reconstruction, to achieve high-quality, high-SNR and submillimeter isotropic resolution (0.85 × 0.85 × 0.85 mm3) in vivo human brain DTI on a 3 Tesla clinical MRI scanner. In agreement with the previously reported post-mortem human brain DTI study, our in vivo data show that the structural connectivity networks of human brains can be mapped more accurately and completely with high-resolution DTI as compared with conventional DTI (e.g., 2 × 2 × 2 mm3). PMID:26072250
Survey of currently available high-resolution raster graphics systems
NASA Technical Reports Server (NTRS)
Jones, Denise R.
1987-01-01
Presented are data obtained on high-resolution raster graphics engines currently available on the market. The data were obtained through survey responses received from various vendors and also from product literature. The questionnaire developed for this survey was basically a list of characteristics desired in a high performance color raster graphics system which could perform real-time aircraft simulations. Several vendors responded to the survey, with most reporting on their most advanced high-performance, high-resolution raster graphics engine.
Bibliography of In-House and Contract Reports. Supplement 17
1991-10-01
Area Exit Pupil Viewer ETL-0399 1985 63 TILE REPORT NO. YEAR Extension of Kendall’s Concordance Test Where ETL-0316 1983 Ties are Allowed, An Extraction...Phase 11 ETL-0360 1984 High Resolution Optical Power Spectrum Analyzer ETL-0127 1978 High Resolution Orthophoto Output Table (HIROOT) AD 856 731L 1969...High Resolution Orthophoto Output Table ETL-ETR-72-3 1972 High Speed Disc Memory and a Color Image AD 878 975L 1970 Display for a Small Computer High
NASA Astrophysics Data System (ADS)
Rimac, Antonija; von Storch, Jin-Song; Eden, Carsten
2013-04-01
The estimated power required to sustain global general circulation in the ocean is about 2 TW. This power is supplied with wind stress and tides. Energy spectrum shows pronounced maxima at near-inertial frequency. Near-inertial waves excited by high-frequency winds represent an important source for deep ocean mixing since they can propagate into the deep ocean and dissipate far away from the generation sites. The energy input by winds to near-inertial waves has been studied mostly using slab ocean models and wind stress forcing with coarse temporal resolution (e.g. 6-hourly). Slab ocean models lack the ability to reproduce fundamental aspects of kinetic energy balance and systematically overestimate the wind work. Also, slab ocean models do not account the energy used for the mixed layer deepening or the energy radiating downward into the deep ocean. Coarse temporal resolution of the wind forcing strongly underestimates the near-inertial energy. To overcome this difficulty we use an eddy permitting ocean model with high-frequency wind forcing. We establish the following model setup: We use the Max Planck Institute Ocean Model (MPIOM) on a tripolar grid with 45 km horizontal resolution and 40 vertical levels. We run the model with wind forcings that vary in horizontal and temporal resolution. We use high-resolution (1-hourly with 35 km horizontal resolution) and low-resolution winds (6-hourly with 250 km horizontal resolution). We address the following questions: Is the kinetic energy of near-inertial waves enhanced when high-resolution wind forcings are used? If so, is this due to higher level of overall wind variability or higher spatial or temporal resolution of wind forcing? How large is the power of near-inertial waves generated by winds? Our results show that near-inertial waves are enhanced and the near-inertial kinetic energy is two times higher (in the storm track regions 3.5 times higher) when high-resolution winds are used. Filtering high-resolution winds in space and time, the near-inertial kinetic energy reduces. The reduction is faster when a temporal filter is used suggesting that the high-frequency wind forcing is more efficient in generating near-inertial wave energy than the small-scale wind forcing. Using low-resolution wind forcing the wind generated power to near-inertial waves is 0.55 TW. When we use high-resolution wind forcing the result is 1.6 TW meaning that the result increases by 300%.
Yuan, Baohong; Pei, Yanbo; Kandukuri, Jayanth
2013-01-01
Our recently developed ultrasound-switchable fluorescence (USF) imaging technique showed that it was feasible to conduct high-resolution fluorescence imaging in a centimeter-deep turbid medium. Because the spatial resolution of this technique highly depends on the ultrasound-induced temperature focal size (UTFS), minimization of UTFS becomes important for further improving the spatial resolution USF technique. In this study, we found that UTFS can be significantly reduced below the diffraction-limited acoustic intensity focal size via nonlinear acoustic effects and thermal confinement by appropriately controlling ultrasound power and exposure time, which can be potentially used for deep-tissue high-resolution imaging. PMID:23479498
Beamline P02.1 at PETRA III for high-resolution and high-energy powder diffraction
Dippel, Ann-Christin; Liermann, Hanns-Peter; Delitz, Jan Torben; Walter, Peter; Schulte-Schrepping, Horst; Seeck, Oliver H.; Franz, Hermann
2015-01-01
Powder X-ray diffraction techniques largely benefit from the superior beam quality provided by high-brilliance synchrotron light sources in terms of photon flux and angular resolution. The High Resolution Powder Diffraction Beamline P02.1 at the storage ring PETRA III (DESY, Hamburg, Germany) combines these strengths with the power of high-energy X-rays for materials research. The beamline is operated at a fixed photon energy of 60 keV (0.207 Å wavelength). A high-resolution monochromator generates the highly collimated X-ray beam of narrow energy bandwidth. Classic crystal structure determination in reciprocal space at standard and non-ambient conditions are an essential part of the scientific scope as well as total scattering analysis using the real space information of the pair distribution function. Both methods are complemented by in situ capabilities with time-resolution in the sub-second regime owing to the high beam intensity and the advanced detector technology for high-energy X-rays. P02.1’s efficiency in solving chemical and crystallographic problems is illustrated by presenting key experiments that were carried out within these fields during the early stage of beamline operation. PMID:25931084
[Possibile application of X-ray and high resolution CT in pneumoconiosis management].
Vlasov, V G; Laptev, V Ia; Logvinenko, I I; Smirnova, E L; Brovchenko, E P; Mironova, M V
2011-01-01
The article covers results of clinical and roentgenologic data analysis. The data were obtained in the study that covered 447 pneumoconiosis patients, 75 of which were subjected to high resolution CT. If compared to chest X-ray, high resolution CT helps more precise forecast of further course in pneumoconiosis.
Urban cover mapping using digital, high-resolution aerial imagery
Soojeong Myeong; David J. Nowak; Paul F. Hopkins; Robert H. Brock
2003-01-01
High-spatial resolution digital color-infrared aerial imagery of Syracuse, NY was analyzed to test methods for developing land cover classifications for an urban area. Five cover types were mapped: tree/shrub, grass/herbaceous, bare soil, water and impervious surface. Challenges in high-spatial resolution imagery such as shadow effect and similarity in spectral...
High resolution manometry findings in patients with esophageal epiphrenic diverticula.
Vicentine, Fernando P P; Herbella, Fernando A M; Silva, Luciana C; Patti, Marco G
2011-12-01
The pathophysiology of esophageal epiphrenic diverticula is still uncertain even though a concomitant motility disorder is found in the majority of patients in different series. High resolution manometry may allow detection of motor abnormalities in a higher number of patients with esophageal epiphrenic diverticula compared with conventional manometry. This study aims to evaluate the high resolution manometry findings in patients with esophageal epiphrenic diverticula. Nine individuals (mean age 63 ± 10 years, 4 females) with esophageal epiphrenic diverticula underwent high resolution manometry. A single diverticulum was observed in eight patients and multiple diverticula in one. Visual analysis of conventional tracings and color pressure plots for identification of segmental abnormalities was performed by two researchers experienced in high resolution manometry. Upper esophageal sphincter was normal in all patients. Esophageal body was abnormal in eight patients; lower esophageal sphincter was abnormal in seven patients. Named esophageal motility disorders were found in seven patients: achalasia in six, diffuse esophageal spasm in one. In one patient, a segmental hypercontractile zone was noticed with pressure of 196 mm Hg. High resolution manometry demonstrated motor abnormalities in all patients with esophageal epiphrenic diverticula.
NASA Astrophysics Data System (ADS)
Yao, C.; Zhang, Y.; Zhang, Y.; Liu, H.
2017-09-01
With the rapid development of Precision Agriculture (PA) promoted by high-resolution remote sensing, it makes significant sense in management and estimation of agriculture through crop classification of high-resolution remote sensing image. Due to the complex and fragmentation of the features and the surroundings in the circumstance of high-resolution, the accuracy of the traditional classification methods has not been able to meet the standard of agricultural problems. In this case, this paper proposed a classification method for high-resolution agricultural remote sensing images based on convolution neural networks(CNN). For training, a large number of training samples were produced by panchromatic images of GF-1 high-resolution satellite of China. In the experiment, through training and testing on the CNN under the toolbox of deep learning by MATLAB, the crop classification finally got the correct rate of 99.66 % after the gradual optimization of adjusting parameter during training. Through improving the accuracy of image classification and image recognition, the applications of CNN provide a reference value for the field of remote sensing in PA.
High Resolution PET with 250 micrometer LSO Detectors and Adaptive Zoom
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cherry, Simon R.; Qi, Jinyi
2012-01-08
There have been impressive improvements in the performance of small-animal positron emission tomography (PET) systems since their first development in the mid 1990s, both in terms of spatial resolution and sensitivity, which have directly contributed to the increasing adoption of this technology for a wide range of biomedical applications. Nonetheless, current systems still are largely dominated by the size of the scintillator elements used in the detector. Our research predicts that developing scintillator arrays with an element size of 250 {micro}m or smaller will lead to an image resolution of 500 {micro}m when using 18F- or 64Cu-labeled radiotracers, giving amore » factor of 4-8 improvement in volumetric resolution over the highest resolution research systems currently in existence. This proposal had two main objectives: (i) To develop and evaluate much higher resolution and efficiency scintillator arrays that can be used in the future as the basis for detectors in a small-animal PET scanner where the spatial resolution is dominated by decay and interaction physics rather than detector size. (ii) To optimize one such high resolution, high sensitivity detector and adaptively integrate it into the existing microPET II small animal PET scanner as a 'zoom-in' detector that provides higher spatial resolution and sensitivity in a limited region close to the detector face. The knowledge gained from this project will provide valuable information for building future PET systems with a complete ring of very high-resolution detector arrays and also lay the foundations for utilizing high-resolution detectors in combination with existing PET systems for localized high-resolution imaging.« less
FALCON: fast and unbiased reconstruction of high-density super-resolution microscopy data
NASA Astrophysics Data System (ADS)
Min, Junhong; Vonesch, Cédric; Kirshner, Hagai; Carlini, Lina; Olivier, Nicolas; Holden, Seamus; Manley, Suliana; Ye, Jong Chul; Unser, Michael
2014-04-01
Super resolution microscopy such as STORM and (F)PALM is now a well known method for biological studies at the nanometer scale. However, conventional imaging schemes based on sparse activation of photo-switchable fluorescent probes have inherently slow temporal resolution which is a serious limitation when investigating live-cell dynamics. Here, we present an algorithm for high-density super-resolution microscopy which combines a sparsity-promoting formulation with a Taylor series approximation of the PSF. Our algorithm is designed to provide unbiased localization on continuous space and high recall rates for high-density imaging, and to have orders-of-magnitude shorter run times compared to previous high-density algorithms. We validated our algorithm on both simulated and experimental data, and demonstrated live-cell imaging with temporal resolution of 2.5 seconds by recovering fast ER dynamics.
FALCON: fast and unbiased reconstruction of high-density super-resolution microscopy data
Min, Junhong; Vonesch, Cédric; Kirshner, Hagai; Carlini, Lina; Olivier, Nicolas; Holden, Seamus; Manley, Suliana; Ye, Jong Chul; Unser, Michael
2014-01-01
Super resolution microscopy such as STORM and (F)PALM is now a well known method for biological studies at the nanometer scale. However, conventional imaging schemes based on sparse activation of photo-switchable fluorescent probes have inherently slow temporal resolution which is a serious limitation when investigating live-cell dynamics. Here, we present an algorithm for high-density super-resolution microscopy which combines a sparsity-promoting formulation with a Taylor series approximation of the PSF. Our algorithm is designed to provide unbiased localization on continuous space and high recall rates for high-density imaging, and to have orders-of-magnitude shorter run times compared to previous high-density algorithms. We validated our algorithm on both simulated and experimental data, and demonstrated live-cell imaging with temporal resolution of 2.5 seconds by recovering fast ER dynamics. PMID:24694686
The Joint Astrophysical Plasmadynamic Experiment (J-PEX): a high-resolution rocket spectrometer
NASA Astrophysics Data System (ADS)
Barstow, Martin A.; Bannister, Nigel P.; Cruddace, Raymond G.; Kowalski, Michael P.; Wood, Kent S.; Yentis, Daryl J.; Gursky, Herbert; Barbee, Troy W., Jr.; Goldstein, William H.; Kordas, Joseph F.; Fritz, Gilbert G.; Culhane, J. Leonard; Lapington, Jonathan S.
2003-02-01
We report on the successful sounding rocket flight of the high resolution (R=3000-4000) J-PEX EUV spectrometer. J-PEX is a novel normal incidence instrument, which combines the focusing and dispersive elements of the spectrometer into a single optical element, a multilayer-coated grating. The high spectral resolution achieved has had to be matched by unprecedented high spatial resolution in the imaging microchannel plate detector used to record the data. We illustrate the performance of the complete instrument through an analysis of the 220-245Å spectrum of the white dwarf G191-B2B obtained with a 300 second exposure. The high resolution allows us to detect a low-density ionized helium component along the line of sight to the star and individual absorption lines from heavier elements in the photosphere.
Flat field concave holographic grating with broad spectral region and moderately high resolution.
Wu, Jian Fen; Chen, Yong Yan; Wang, Tai Sheng
2012-02-01
In order to deal with the conflicts between broad spectral region and high resolution in compact spectrometers based on a flat field concave holographic grating and line array CCD, we present a simple and practical method to design a flat field concave holographic grating that is capable of imaging a broad spectral region at a moderately high resolution. First, we discuss the principle of realizing a broad spectral region and moderately high resolution. Second, we provide the practical method to realize our ideas, in which Namioka grating theory, a genetic algorithm, and ZEMAX are used to reach this purpose. Finally, a near-normal-incidence example modeled in ZEMAX is shown to verify our ideas. The results show that our work probably has a general applicability in compact spectrometers with a broad spectral region and moderately high resolution.
Impacts of high resolution data on traveler compliance levels in emergency evacuation simulations
Lu, Wei; Han, Lee D.; Liu, Cheng; ...
2016-05-05
In this article, we conducted a comparison study of evacuation assignment based on Traffic Analysis Zones (TAZ) and high resolution LandScan USA Population Cells (LPC) with detailed real world roads network. A platform for evacuation modeling built on high resolution population distribution data and activity-based microscopic traffic simulation was proposed. This platform can be extended to any cities in the world. The results indicated that evacuee compliance behavior affects evacuation efficiency with traditional TAZ assignment, but it did not significantly compromise the performance with high resolution LPC assignment. The TAZ assignment also underestimated the real travel time during evacuation. Thismore » suggests that high data resolution can improve the accuracy of traffic modeling and simulation. The evacuation manager should consider more diverse assignment during emergency evacuation to avoid congestions.« less
NASA Astrophysics Data System (ADS)
Watanabe, A.; Furukawa, H.
2018-04-01
The resolution of multichannel Fourier transform (McFT) spectroscopy is insufficient for many applications despite its extreme advantage of high throughput. We propose an improved configuration to realise both performance using a two-dimensional area sensor. For the spectral resolution, we obtained the interferogram of a larger optical path difference by shifting the area sensor without altering any optical components. The non-linear phase error of the interferometer was successfully corrected using a phase-compensation calculation. Warping compensation was also applied to realise a higher throughput to accumulate the signal between vertical pixels. Our approach significantly improved the resolution and signal-to-noise ratio by factors of 1.7 and 34, respectively. This high-resolution and high-sensitivity McFT spectrometer will be useful for detecting weak light signals such as those in non-invasive diagnosis.
Rayleigh-wave mode separation by high-resolution linear radon transform
Luo, Y.; Xia, J.; Miller, R.D.; Xu, Y.; Liu, J.; Liu, Q.
2009-01-01
Multichannel analysis of surface waves (MASW) method is an effective tool for obtaining vertical shear wave profiles from a single non-invasive measurement. One key step of the MASW method is generation of a dispersion image and extraction of a reliable dispersion curve from raw multichannel shot records. Because different Rayleigh-wave modes normally interfere with each other in the time and space domain, it is necessary to perform mode separation and reconstruction to increase the accuracy of phase velocities determined from a dispersion image. In this paper, we demonstrate the effectiveness of high-resolution linear Radon transform (LRT) as a means of separating and reconstructing multimode, dispersive Rayleigh-wave energy. We first introduce high-resolution LRT methods and Rayleigh-wave mode separation using high-resolution LRT. Next, we use synthetic data and a real-world example to demonstrate the effectiveness of Rayleigh-wave mode separation using high-resolution LRT. Our synthetic and real-world results demonstrate that (1) high-resolution LRT successfully separates and reconstructs multimode dispersive Rayleigh-wave energy with high resolution allowing the multimode energy to be more accurately determined. The horizontal resolution of the Rayleigh-wave method can be increased by extraction of dispersion curves from a pair of traces in the mode-separated shot gather and (2) multimode separation and reconstruction expand the usable frequency range of higher mode dispersive energy, which increases the depth of investigation and provides a means for accurately determining cut-off frequencies. ?? 2009 The Authors Journal compilation ?? 2009 RAS.
Kuribayashi, Ryuma; Nittono, Hiroshi
2017-01-01
High-resolution audio has a higher sampling frequency and a greater bit depth than conventional low-resolution audio such as compact disks. The higher sampling frequency enables inaudible sound components (above 20 kHz) that are cut off in low-resolution audio to be reproduced. Previous studies of high-resolution audio have mainly focused on the effect of such high-frequency components. It is known that alpha-band power in a human electroencephalogram (EEG) is larger when the inaudible high-frequency components are present than when they are absent. Traditionally, alpha-band EEG activity has been associated with arousal level. However, no previous studies have explored whether sound sources with high-frequency components affect the arousal level of listeners. The present study examined this possibility by having 22 participants listen to two types of a 400-s musical excerpt of French Suite No. 5 by J. S. Bach (on cembalo, 24-bit quantization, 192 kHz A/D sampling), with or without inaudible high-frequency components, while performing a visual vigilance task. High-alpha (10.5-13 Hz) and low-beta (13-20 Hz) EEG powers were larger for the excerpt with high-frequency components than for the excerpt without them. Reaction times and error rates did not change during the task and were not different between the excerpts. The amplitude of the P3 component elicited by target stimuli in the vigilance task increased in the second half of the listening period for the excerpt with high-frequency components, whereas no such P3 amplitude change was observed for the other excerpt without them. The participants did not distinguish between these excerpts in terms of sound quality. Only a subjective rating of inactive pleasantness after listening was higher for the excerpt with high-frequency components than for the other excerpt. The present study shows that high-resolution audio that retains high-frequency components has an advantage over similar and indistinguishable digital sound sources in which such components are artificially cut off, suggesting that high-resolution audio with inaudible high-frequency components induces a relaxed attentional state without conscious awareness.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kim, Jungho
Hard x-ray resonant inelastic x-ray scattering (RIXS) is a promising x-ray spectroscopic tool for measuring low-energy excitation spectra at high pressure which have been stymied heretofore by the technical difficulties inherent in measuring a sample held at high pressure in a diamond anvil cell. The currently available facilities of high resolution (< 200 meV) RIXS has been used to probe low-energy excitation spectra from the diamond anvil cell, by virtue of advanced photon detection instrumentations of high-brilliance synchrotron x-ray radiation sources. Compared to a structural elastic scattering and x-ray emission, RIXS is a photon hungry technique and high-resolution RIXS undermore » high pressure is at its infancy stage. In this review, the fundamentals of RIXS including instrumentation of high-resolution RIXS are presented and then experimental details of diamond anvil cell, sample preparation and measurement geometry are discussed. Experimental data of 3d and 5d transition metal oxides are presented. Finally, future improvements in high-resolution RIXS instrumentation for the high pressure experiment is discussed.« less
Fuzzy Classification of High Resolution Remote Sensing Scenes Using Visual Attention Features.
Li, Linyi; Xu, Tingbao; Chen, Yun
2017-01-01
In recent years the spatial resolutions of remote sensing images have been improved greatly. However, a higher spatial resolution image does not always lead to a better result of automatic scene classification. Visual attention is an important characteristic of the human visual system, which can effectively help to classify remote sensing scenes. In this study, a novel visual attention feature extraction algorithm was proposed, which extracted visual attention features through a multiscale process. And a fuzzy classification method using visual attention features (FC-VAF) was developed to perform high resolution remote sensing scene classification. FC-VAF was evaluated by using remote sensing scenes from widely used high resolution remote sensing images, including IKONOS, QuickBird, and ZY-3 images. FC-VAF achieved more accurate classification results than the others according to the quantitative accuracy evaluation indices. We also discussed the role and impacts of different decomposition levels and different wavelets on the classification accuracy. FC-VAF improves the accuracy of high resolution scene classification and therefore advances the research of digital image analysis and the applications of high resolution remote sensing images.
Fuzzy Classification of High Resolution Remote Sensing Scenes Using Visual Attention Features
Xu, Tingbao; Chen, Yun
2017-01-01
In recent years the spatial resolutions of remote sensing images have been improved greatly. However, a higher spatial resolution image does not always lead to a better result of automatic scene classification. Visual attention is an important characteristic of the human visual system, which can effectively help to classify remote sensing scenes. In this study, a novel visual attention feature extraction algorithm was proposed, which extracted visual attention features through a multiscale process. And a fuzzy classification method using visual attention features (FC-VAF) was developed to perform high resolution remote sensing scene classification. FC-VAF was evaluated by using remote sensing scenes from widely used high resolution remote sensing images, including IKONOS, QuickBird, and ZY-3 images. FC-VAF achieved more accurate classification results than the others according to the quantitative accuracy evaluation indices. We also discussed the role and impacts of different decomposition levels and different wavelets on the classification accuracy. FC-VAF improves the accuracy of high resolution scene classification and therefore advances the research of digital image analysis and the applications of high resolution remote sensing images. PMID:28761440
Single-shot and single-sensor high/super-resolution microwave imaging based on metasurface.
Wang, Libo; Li, Lianlin; Li, Yunbo; Zhang, Hao Chi; Cui, Tie Jun
2016-06-01
Real-time high-resolution (including super-resolution) imaging with low-cost hardware is a long sought-after goal in various imaging applications. Here, we propose broadband single-shot and single-sensor high-/super-resolution imaging by using a spatio-temporal dispersive metasurface and an imaging reconstruction algorithm. The metasurface with spatio-temporal dispersive property ensures the feasibility of the single-shot and single-sensor imager for super- and high-resolution imaging, since it can convert efficiently the detailed spatial information of the probed object into one-dimensional time- or frequency-dependent signal acquired by a single sensor fixed in the far-field region. The imaging quality can be improved by applying a feature-enhanced reconstruction algorithm in post-processing, and the desired imaging resolution is related to the distance between the object and metasurface. When the object is placed in the vicinity of the metasurface, the super-resolution imaging can be realized. The proposed imaging methodology provides a unique means to perform real-time data acquisition, high-/super-resolution images without employing expensive hardware (e.g. mechanical scanner, antenna array, etc.). We expect that this methodology could make potential breakthroughs in the areas of microwave, terahertz, optical, and even ultrasound imaging.
New concept high-speed and high-resolution color scanner
NASA Astrophysics Data System (ADS)
Nakashima, Keisuke; Shinoda, Shin'ichi; Konishi, Yoshiharu; Sugiyama, Kenji; Hori, Tetsuya
2003-05-01
We have developed a new concept high-speed and high-resolution color scanner (Blinkscan) using digital camera technology. With our most advanced sub-pixel image processing technology, approximately 12 million pixel image data can be captured. High resolution imaging capability allows various uses such as OCR, color document read, and document camera. The scan time is only about 3 seconds for a letter size sheet. Blinkscan scans documents placed "face up" on its scan stage and without any special illumination lights. Using Blinkscan, a high-resolution color document can be easily inputted into a PC at high speed, a paperless system can be built easily. It is small, and since the occupancy area is also small, setting it on an individual desk is possible. Blinkscan offers the usability of a digital camera and accuracy of a flatbed scanner with high-speed processing. Now, about several hundred of Blinkscan are mainly shipping for the receptionist operation in a bank and a security. We will show the high-speed and high-resolution architecture of Blinkscan. Comparing operation-time with conventional image capture device, the advantage of Blinkscan will make clear. And image evaluation for variety of environment, such as geometric distortions or non-uniformity of brightness, will be made.
NASA Astrophysics Data System (ADS)
Ogawa, Masahiko; Shidoji, Kazunori
2011-03-01
High-resolution stereoscopic images are effective for use in virtual reality and teleoperation systems. However, the higher the image resolution, the higher is the cost of computer processing and communication. To reduce this cost, numerous earlier studies have suggested the use of multi-resolution images, which have high resolution in region of interests and low resolution in other areas. However, observers can perceive unpleasant sensations and incorrect depth because they can see low-resolution areas in their field of vision. In this study, we conducted an experiment to research the relationship between the viewing field and the perception of image resolution, and determined respective thresholds of image-resolution perception for various positions of the viewing field. The results showed that participants could not distinguish between the high-resolution stimulus and the decreased stimulus, 63 ppi, at positions more than 8 deg outside the gaze point. Moreover, with positions shifted a further 11 and 13 deg from the gaze point, participants could not distinguish between the high-resolution stimulus and the decreased stimuli whose resolution densities were 42 and 25 ppi. Hence, we will propose the composition of multi-resolution images in which observers do not perceive unpleasant sensations and incorrect depth with data reduction (compression).
High-resolution MRI in detecting subareolar breast abscess.
Fu, Peifen; Kurihara, Yasuyuki; Kanemaki, Yoshihide; Okamoto, Kyoko; Nakajima, Yasuo; Fukuda, Mamoru; Maeda, Ichiro
2007-06-01
Because subareolar breast abscess has a high recurrence rate, a more effective imaging technique is needed to comprehensively visualize the lesions and guide surgery. We performed a high-resolution MRI technique using a microscopy coil to reveal the characteristics and extent of subareolar breast abscess. High-resolution MRI has potential diagnostic value in subareolar breast abscess. This technique can be used to guide surgery with the aim of reducing the recurrence rate.
MRI Superresolution Using Self-Similarity and Image Priors
Manjón, José V.; Coupé, Pierrick; Buades, Antonio; Collins, D. Louis; Robles, Montserrat
2010-01-01
In Magnetic Resonance Imaging typical clinical settings, both low- and high-resolution images of different types are routinarily acquired. In some cases, the acquired low-resolution images have to be upsampled to match with other high-resolution images for posterior analysis or postprocessing such as registration or multimodal segmentation. However, classical interpolation techniques are not able to recover the high-frequency information lost during the acquisition process. In the present paper, a new superresolution method is proposed to reconstruct high-resolution images from the low-resolution ones using information from coplanar high resolution images acquired of the same subject. Furthermore, the reconstruction process is constrained to be physically plausible with the MR acquisition model that allows a meaningful interpretation of the results. Experiments on synthetic and real data are supplied to show the effectiveness of the proposed approach. A comparison with classical state-of-the-art interpolation techniques is presented to demonstrate the improved performance of the proposed methodology. PMID:21197094
Image quality improvement in cone-beam CT using the super-resolution technique.
Oyama, Asuka; Kumagai, Shinobu; Arai, Norikazu; Takata, Takeshi; Saikawa, Yusuke; Shiraishi, Kenshiro; Kobayashi, Takenori; Kotoku, Jun'ichi
2018-04-05
This study was conducted to improve cone-beam computed tomography (CBCT) image quality using the super-resolution technique, a method of inferring a high-resolution image from a low-resolution image. This technique is used with two matrices, so-called dictionaries, constructed respectively from high-resolution and low-resolution image bases. For this study, a CBCT image, as a low-resolution image, is represented as a linear combination of atoms, the image bases in the low-resolution dictionary. The corresponding super-resolution image was inferred by multiplying the coefficients and the high-resolution dictionary atoms extracted from planning CT images. To evaluate the proposed method, we computed the root mean square error (RMSE) and structural similarity (SSIM). The resulting RMSE and SSIM between the super-resolution images and the planning CT images were, respectively, as much as 0.81 and 1.29 times better than those obtained without using the super-resolution technique. We used super-resolution technique to improve the CBCT image quality.
40 CFR 766.16 - Developing the analytical test method.
Code of Federal Regulations, 2011 CFR
2011-07-01
... Resolution Gas Chromatography (HRGC) with High Resolution Mass Spectrometry (HRMS) is the method of choice... meet the requirements of the chemical matrix. (d) Analysis. The method of choice is High Resolution Gas...
40 CFR 766.16 - Developing the analytical test method.
Code of Federal Regulations, 2010 CFR
2010-07-01
... Resolution Gas Chromatography (HRGC) with High Resolution Mass Spectrometry (HRMS) is the method of choice... meet the requirements of the chemical matrix. (d) Analysis. The method of choice is High Resolution Gas...
High resolution NMR imaging using a high field yokeless permanent magnet.
Kose, Katsumi; Haishi, Tomoyuki
2011-01-01
We measured the homogeneity and stability of the magnetic field of a high field (about 1.04 tesla) yokeless permanent magnet with 40-mm gap for high resolution nuclear magnetic resonance (NMR) imaging. Homogeneity was evaluated using a 3-dimensional (3D) lattice phantom and 3D spin-echo imaging sequences. In the central sphere (20-mm diameter), peak-to-peak magnetic field inhomogeneity was about 60 ppm, and the root-mean-square was 8 ppm. We measured room temperature, magnet temperature, and NMR frequency of the magnet simultaneously every minute for about 68 hours with and without the thermal insulator of the magnet. A simple mathematical model described the magnet's thermal property. Based on magnet performance, we performed high resolution (up to [20 µm](2)) imaging with internal NMR lock sequences of several biological samples. Our results demonstrated the usefulness of the high field small yokeless permanent magnet for high resolution NMR imaging.
NASA Astrophysics Data System (ADS)
Lefebvre, Joël.; Castonguay, Alexandre; Lesage, Frédéric
2018-02-01
High resolution imaging of whole rodent brains using serial OCT scanners is a promising method to investigate microstructural changes in tissue related to the evolution of neuropathologies. Although micron to sub-micron sampling resolution can be obtained by using high numerical aperture objectives and dynamic focusing, such an imaging system is not adapted to whole brain imaging. This is due to the large amount of data it generates and the significant computational resources required for reconstructing such volumes. To address this limitation, a dual resolution serial OCT scanner was developed. The optical setup consists in a swept-source OCT made of two sample and reference arms, each arm being coupled with different microscope objectives (3X / 40X). Motorized flip mirrors were used to switch between each OCT arm, thus allowing low and high resolution acquisitions within the same sample. The low resolution OCT volumes acquired with the 3X arm were stitched together, providing a 3D map of the whole mouse brain. This brain can be registered to an OCT brain template to enable neurological structures localization. The high resolution volumes acquired with the 40X arm were also stitched together to create local high resolution 3D maps of the tissue microstructure. The 40X data can be acquired at any arbitrary location in the sample, thus limiting storage-heavy high resolution data to application restricted to specific regions of interest. By providing dual-resolution OCT data, this setup can be used to validate diffusion MRI with tissue microstructure derived metrics measured at any location in ex vivo brains.
2016-06-16
procedure. The predictive capabilities of the high-resolution computational fluid dynamics ( CFD ) simulations of urban flow are validated against a very...turbulence over a 2D building array using high-resolution CFD and a distributed drag force approach a Department of Mechanical Engineering, University
Midekisa, Alemayehu; Holl, Felix; Savory, David J; Andrade-Pacheco, Ricardo; Gething, Peter W; Bennett, Adam; Sturrock, Hugh J W
2017-01-01
Quantifying and monitoring the spatial and temporal dynamics of the global land cover is critical for better understanding many of the Earth's land surface processes. However, the lack of regularly updated, continental-scale, and high spatial resolution (30 m) land cover data limit our ability to better understand the spatial extent and the temporal dynamics of land surface changes. Despite the free availability of high spatial resolution Landsat satellite data, continental-scale land cover mapping using high resolution Landsat satellite data was not feasible until now due to the need for high-performance computing to store, process, and analyze this large volume of high resolution satellite data. In this study, we present an approach to quantify continental land cover and impervious surface changes over a long period of time (15 years) using high resolution Landsat satellite observations and Google Earth Engine cloud computing platform. The approach applied here to overcome the computational challenges of handling big earth observation data by using cloud computing can help scientists and practitioners who lack high-performance computational resources.
Holl, Felix; Savory, David J.; Andrade-Pacheco, Ricardo; Gething, Peter W.; Bennett, Adam; Sturrock, Hugh J. W.
2017-01-01
Quantifying and monitoring the spatial and temporal dynamics of the global land cover is critical for better understanding many of the Earth’s land surface processes. However, the lack of regularly updated, continental-scale, and high spatial resolution (30 m) land cover data limit our ability to better understand the spatial extent and the temporal dynamics of land surface changes. Despite the free availability of high spatial resolution Landsat satellite data, continental-scale land cover mapping using high resolution Landsat satellite data was not feasible until now due to the need for high-performance computing to store, process, and analyze this large volume of high resolution satellite data. In this study, we present an approach to quantify continental land cover and impervious surface changes over a long period of time (15 years) using high resolution Landsat satellite observations and Google Earth Engine cloud computing platform. The approach applied here to overcome the computational challenges of handling big earth observation data by using cloud computing can help scientists and practitioners who lack high-performance computational resources. PMID:28953943
NASA Technical Reports Server (NTRS)
Menzel, W. Paul; Moeller, Christopher C.; Smith, William L.
1991-01-01
This program has applied Multispectral Atmospheric Mapping Sensor (MAMS) high resolution data to the problem of monitoring atmospheric quantities of moisture and radiative flux at small spatial scales. MAMS, with 100-m horizontal resolution in its four infrared channels, was developed to study small scale atmospheric moisture and surface thermal variability, especially as related to the development of clouds, precipitation, and severe storms. High-resolution Interferometer Sounder (HIS) data has been used to develop a high spectral resolution retrieval algorithm for producing vertical profiles of atmospheric temperature and moisture. The results of this program are summarized and a list of publications resulting from this contract is presented. Selected publications are attached as an appendix.
Donegan, Ryan J; Stauffer, Anthony; Heaslet, Michael; Poliskie, Michael
Plantar plate pathology has gained noticeable attention in recent years as an etiology of lesser metatarsophalangeal joint pain. The heightened clinical awareness has led to the need for more effective diagnostic imaging accuracy. Numerous reports have established the accuracy of both magnetic resonance imaging and ultrasonography for the diagnosis of plantar plate pathology. However, no conclusions have been made regarding which is the superior imaging modality. The present study reports a case series directly comparing high-resolution dynamic ultrasonography and magnetic resonance imaging. A multicenter retrospective comparison of magnetic resonance imaging versus high-resolution dynamic ultrasonography to evaluate plantar plate pathology with surgical confirmation was conducted. The sensitivity, specificity, and positive and negative predictive values for magnetic resonance imaging were 60%, 100%, 100%, and 33%, respectively. The overall diagnostic accuracy compared with the intraoperative findings was 66%. The sensitivity, specificity, and positive and negative predictive values for high-resolution dynamic ultrasound imaging were 100%, 100%, 100%, and 100%, respectively. The overall diagnostic accuracy compared with the intraoperative findings was 100%. The p value using Fisher's exact test for magnetic resonance imaging and high-resolution dynamic ultrasonography was p = .45, a difference that was not statistically significant. High-resolution dynamic ultrasonography had greater accuracy than magnetic resonance imaging in diagnosing lesser metatarsophalangeal joint plantar plate pathology, although the difference was not statistically significant. The present case series suggests that high-resolution dynamic ultrasonography can be considered an equally accurate imaging modality for plantar plate pathology at a potential cost savings compared with magnetic resonance imaging. Therefore, high-resolution dynamic ultrasonography warrants further investigation in a prospective study. Copyright © 2016 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.
Adaptive optics high-resolution IR spectroscopy with silicon grisms and immersion gratings
NASA Astrophysics Data System (ADS)
Ge, Jian; McDavitt, Daniel L.; Chakraborty, Abhijit; Bernecker, John L.; Miller, Shane
2003-02-01
The breakthrough of silicon immersion grating technology at Penn State has the ability to revolutionize high-resolution infrared spectroscopy when it is coupled with adaptive optics at large ground-based telescopes. Fabrication of high quality silicon grism and immersion gratings up to 2 inches in dimension, less than 1% integrated scattered light, and diffraction-limited performance becomes a routine process thanks to newly developed techniques. Silicon immersion gratings with etched dimensions of ~ 4 inches are being developed at Penn State. These immersion gratings will be able to provide a diffraction-limited spectral resolution of R = 300,000 at 2.2 micron, or 130,000 at 4.6 micron. Prototype silicon grisms have been successfully used in initial scientific observations at the Lick 3m telescope with adaptive optics. Complete K band spectra of a total of 6 T Tauri and Ae/Be stars and their close companions at a spectral resolution of R ~ 3000 were obtained. This resolving power was achieved by using a silicon echelle grism with a 5 mm pupil diameter in an IR camera. These results represent the first scientific observations conducted by the high-resolution silicon grisms, and demonstrate the extremely high dispersing power of silicon-based gratings. New discoveries from this high spatial and spectral resolution IR spectroscopy will be reported. The future of silicon-based grating applications in ground-based AO IR instruments is promising. Silicon immersion gratings will make very high-resolution spectroscopy (R > 100,000) feasible with compact instruments for implementation on large telescopes. Silicon grisms will offer an efficient way to implement low-cost medium to high resolution IR spectroscopy (R ~ 1000-50000) through the conversion of existing cameras into spectrometers by locating a grism in the instrument's pupil location.
High-resolution harmonic motion imaging (HR-HMI) for tissue biomechanical property characterization
Ma, Teng; Qian, Xuejun; Chiu, Chi Tat; Yu, Mingyue; Jung, Hayong; Tung, Yao-Sheng; Shung, K. Kirk
2015-01-01
Background Elastography, capable of mapping the biomechanical properties of biological tissues, serves as a useful technique for clinicians to perform disease diagnosis and determine stages of many diseases. Many acoustic radiation force (ARF) based elastography, including acoustic radiation force impulse (ARFI) imaging and harmonic motion imaging (HMI), have been developed to remotely assess the elastic properties of tissues. However, due to the lower operating frequencies of these approaches, their spatial resolutions are insufficient for revealing stiffness distribution on small scale applications, such as cancerous tumor margin detection, atherosclerotic plaque composition analysis and ophthalmologic tissue characterization. Though recently developed ARF-based optical coherence elastography (OCE) methods open a new window for the high resolution elastography, shallow imaging depths significantly limit their usefulness in clinics. Methods The aim of this study is to develop a high-resolution HMI method to assess the tissue biomechanical properties with acceptable field of view (FOV) using a 4 MHz ring transducer for efficient excitation and a 40 MHz needle transducer for accurate detection. Under precise alignment of two confocal transducers, the high-resolution HMI system has a lateral resolution of 314 µm and an axial resolution of 147 µm with an effective FOV of 2 mm in depth. Results The performance of this high resolution imaging system was validated on the agar-based tissue mimicking phantoms with different stiffness distributions. These data demonstrated the imaging system’s improved resolution and sensitivity on differentiating materials with varying stiffness. In addition, ex vivo imaging of a human atherosclerosis coronary artery demonstrated the capability of high resolution HMI in identifying layer-specific structures and characterizing atherosclerotic plaques based on their stiffness differences. Conclusions All together high resolution HMI appears to be a promising ultrasound-only technology for characterizing tissue biomechanical properties at the microstructural level to improve the image-based diseases diagnosis in multiple clinical applications. PMID:25694960
High-resolution harmonic motion imaging (HR-HMI) for tissue biomechanical property characterization.
Ma, Teng; Qian, Xuejun; Chiu, Chi Tat; Yu, Mingyue; Jung, Hayong; Tung, Yao-Sheng; Shung, K Kirk; Zhou, Qifa
2015-02-01
Elastography, capable of mapping the biomechanical properties of biological tissues, serves as a useful technique for clinicians to perform disease diagnosis and determine stages of many diseases. Many acoustic radiation force (ARF) based elastography, including acoustic radiation force impulse (ARFI) imaging and harmonic motion imaging (HMI), have been developed to remotely assess the elastic properties of tissues. However, due to the lower operating frequencies of these approaches, their spatial resolutions are insufficient for revealing stiffness distribution on small scale applications, such as cancerous tumor margin detection, atherosclerotic plaque composition analysis and ophthalmologic tissue characterization. Though recently developed ARF-based optical coherence elastography (OCE) methods open a new window for the high resolution elastography, shallow imaging depths significantly limit their usefulness in clinics. The aim of this study is to develop a high-resolution HMI method to assess the tissue biomechanical properties with acceptable field of view (FOV) using a 4 MHz ring transducer for efficient excitation and a 40 MHz needle transducer for accurate detection. Under precise alignment of two confocal transducers, the high-resolution HMI system has a lateral resolution of 314 µm and an axial resolution of 147 µm with an effective FOV of 2 mm in depth. The performance of this high resolution imaging system was validated on the agar-based tissue mimicking phantoms with different stiffness distributions. These data demonstrated the imaging system's improved resolution and sensitivity on differentiating materials with varying stiffness. In addition, ex vivo imaging of a human atherosclerosis coronary artery demonstrated the capability of high resolution HMI in identifying layer-specific structures and characterizing atherosclerotic plaques based on their stiffness differences. All together high resolution HMI appears to be a promising ultrasound-only technology for characterizing tissue biomechanical properties at the microstructural level to improve the image-based diseases diagnosis in multiple clinical applications.
Weber, Stefan A L; Kilpatrick, Jason I; Brosnan, Timothy M; Jarvis, Suzanne P; Rodriguez, Brian J
2014-05-02
Atomic force microscopy (AFM) is widely used in liquid environments, where true atomic resolution at the solid-liquid interface can now be routinely achieved. It is generally expected that AFM operation in more viscous environments results in an increased noise contribution from the thermal motion of the cantilever, thereby reducing the signal-to-noise ratio (SNR). Thus, viscous fluids such as ionic and organic liquids have been generally avoided for high-resolution AFM studies despite their relevance to, e.g. energy applications. Here, we investigate the thermal noise limitations of dynamic AFM operation in both low and high viscosity environments theoretically, deriving expressions for the amplitude, phase and frequency noise resulting from the thermal motion of the cantilever, thereby defining the performance limits of amplitude modulation, phase modulation and frequency modulation AFM. We show that the assumption of a reduced SNR in viscous environments is not inherent to the technique and demonstrate that SNR values comparable to ultra-high vacuum systems can be obtained in high viscosity environments under certain conditions. Finally, we have obtained true atomic resolution images of highly ordered pyrolytic graphite and mica surfaces, thus revealing the potential of high-resolution imaging in high viscosity environments.
NASA Astrophysics Data System (ADS)
Weber, Stefan A. L.; Kilpatrick, Jason I.; Brosnan, Timothy M.; Jarvis, Suzanne P.; Rodriguez, Brian J.
2014-05-01
Atomic force microscopy (AFM) is widely used in liquid environments, where true atomic resolution at the solid-liquid interface can now be routinely achieved. It is generally expected that AFM operation in more viscous environments results in an increased noise contribution from the thermal motion of the cantilever, thereby reducing the signal-to-noise ratio (SNR). Thus, viscous fluids such as ionic and organic liquids have been generally avoided for high-resolution AFM studies despite their relevance to, e.g. energy applications. Here, we investigate the thermal noise limitations of dynamic AFM operation in both low and high viscosity environments theoretically, deriving expressions for the amplitude, phase and frequency noise resulting from the thermal motion of the cantilever, thereby defining the performance limits of amplitude modulation, phase modulation and frequency modulation AFM. We show that the assumption of a reduced SNR in viscous environments is not inherent to the technique and demonstrate that SNR values comparable to ultra-high vacuum systems can be obtained in high viscosity environments under certain conditions. Finally, we have obtained true atomic resolution images of highly ordered pyrolytic graphite and mica surfaces, thus revealing the potential of high-resolution imaging in high viscosity environments.
Light sheet theta microscopy for rapid high-resolution imaging of large biological samples.
Migliori, Bianca; Datta, Malika S; Dupre, Christophe; Apak, Mehmet C; Asano, Shoh; Gao, Ruixuan; Boyden, Edward S; Hermanson, Ola; Yuste, Rafael; Tomer, Raju
2018-05-29
Advances in tissue clearing and molecular labeling methods are enabling unprecedented optical access to large intact biological systems. These developments fuel the need for high-speed microscopy approaches to image large samples quantitatively and at high resolution. While light sheet microscopy (LSM), with its high planar imaging speed and low photo-bleaching, can be effective, scaling up to larger imaging volumes has been hindered by the use of orthogonal light sheet illumination. To address this fundamental limitation, we have developed light sheet theta microscopy (LSTM), which uniformly illuminates samples from the same side as the detection objective, thereby eliminating limits on lateral dimensions without sacrificing the imaging resolution, depth, and speed. We present a detailed characterization of LSTM, and demonstrate its complementary advantages over LSM for rapid high-resolution quantitative imaging of large intact samples with high uniform quality. The reported LSTM approach is a significant step for the rapid high-resolution quantitative mapping of the structure and function of very large biological systems, such as a clarified thick coronal slab of human brain and uniformly expanded tissues, and also for rapid volumetric calcium imaging of highly motile animals, such as Hydra, undergoing non-isomorphic body shape changes.
Fiber optic cable-based high-resolution, long-distance VGA extenders
NASA Astrophysics Data System (ADS)
Rhee, Jin-Geun; Lee, Iksoo; Kim, Heejoon; Kim, Sungjoon; Koh, Yeon-Wan; Kim, Hoik; Lim, Jiseok; Kim, Chur; Kim, Jungwon
2013-02-01
Remote transfer of high-resolution video information finds more applications in detached display applications for large facilities such as theaters, sports complex, airports, and security facilities. Active optical cables (AOCs) provide a promising approach for enhancing both the transmittable resolution and distance that standard copper-based cables cannot reach. In addition to the standard digital formats such as HDMI, the high-resolution, long-distance transfer of VGA format signals is important for applications where high-resolution analog video ports should be also supported, such as military/defense applications and high-resolution video camera links. In this presentation we present the development of a compressionless, high-resolution (up to WUXGA, 1920x1200), long-distance (up to 2 km) VGA extenders based on serialized technique. We employed asynchronous serial transmission and clock regeneration techniques, which enables lower cost implementation of VGA extenders by removing the necessity for clock transmission and large memory at the receiver. Two 3.125-Gbps transceivers are used in parallel to meet the required maximum video data rate of 6.25 Gbps. As the data are transmitted asynchronously, 24-bit pixel clock time stamp is employed to regenerate video pixel clock accurately at the receiver side. In parallel to the video information, stereo audio and RS-232 control signals are transmitted as well.
NASA Astrophysics Data System (ADS)
Sedano, Fernando; Kempeneers, Pieter; Strobl, Peter; Kucera, Jan; Vogt, Peter; Seebach, Lucia; San-Miguel-Ayanz, Jesús
2011-09-01
This study presents a novel cloud masking approach for high resolution remote sensing images in the context of land cover mapping. As an advantage to traditional methods, the approach does not rely on thermal bands and it is applicable to images from most high resolution earth observation remote sensing sensors. The methodology couples pixel-based seed identification and object-based region growing. The seed identification stage relies on pixel value comparison between high resolution images and cloud free composites at lower spatial resolution from almost simultaneously acquired dates. The methodology was tested taking SPOT4-HRVIR, SPOT5-HRG and IRS-LISS III as high resolution images and cloud free MODIS composites as reference images. The selected scenes included a wide range of cloud types and surface features. The resulting cloud masks were evaluated through visual comparison. They were also compared with ad-hoc independently generated cloud masks and with the automatic cloud cover assessment algorithm (ACCA). In general the results showed an agreement in detected clouds higher than 95% for clouds larger than 50 ha. The approach produced consistent results identifying and mapping clouds of different type and size over various land surfaces including natural vegetation, agriculture land, built-up areas, water bodies and snow.
High Resolution CryoFESEM of Microbial Surfaces
NASA Astrophysics Data System (ADS)
Erlandsen, Stanley; Lei, Ming; Martin-Lacave, Ines; Dunny, Gary; Wells, Carol
2003-08-01
The outer surfaces of three microorganisms, Giardia lamblia, Enterococcus faecalis, and Proteus mirabilis, were investigated by cryo-immobilization followed by sublimation of extracellular ice and cryocoating with either Pt alone or Pt plus carbon. Cryocoated samples were examined at [minus sign]125°C in either an in-lens field emission SEM or a below-the-lens field emission SEM. Cryocoating with Pt alone was sufficient for low magnification observation, but attempts to do high-resolution imaging resulted in radiolysis and cracking of the specimen surface. Double coating with Pt and carbon, in combination with high resolution backscatter electron detectors, enabled high-resolution imaging of the glycocalyx of bacteria, revealing a sponge-like network over the surface. High resolution examination of bacterial flagella also revealed a periodic substructure. Common artifacts included radiolysis leading to “cracking” of the surface, and insufficient deposition of Pt resulting in the absence of detectable surface topography.
Research relative to high resolution camera on the advanced X-ray astrophysics facility
NASA Technical Reports Server (NTRS)
1986-01-01
The HRC (High Resolution Camera) is a photon counting instrument to be flown on the Advanced X-Ray Astrophysics Facility (AXAF). It is a large field of view, high angular resolution, detector for the x-ray telescope. The HRC consists of a CsI coated microchannel plate (MCP) acting as a soft x-ray photocathode, followed by a second MCP for high electronic gain. The MCPs are readout by a crossed grid of resistively coupled wires to provide high spatial resolution along with timing and pulse height data. The instrument will be used in two modes, as a direct imaging detector with a limiting sensitivity of 10 to the -15 ergs sq cm sec in a 10 to the 5th second exposure, and as a readout for an objective transmission grating providing spectral resolution of several hundreds to thousands.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Smith, Donald F.; Schulz, Carl; Konijnenburg, Marco
High-resolution Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry imaging enables the spatial mapping and identification of biomolecules from complex surfaces. The need for long time-domain transients, and thus large raw file sizes, results in a large amount of raw data (“big data”) that must be processed efficiently and rapidly. This can be compounded by largearea imaging and/or high spatial resolution imaging. For FT-ICR, data processing and data reduction must not compromise the high mass resolution afforded by the mass spectrometer. The continuous mode “Mosaic Datacube” approach allows high mass resolution visualization (0.001 Da) of mass spectrometry imaging data, butmore » requires additional processing as compared to featurebased processing. We describe the use of distributed computing for processing of FT-ICR MS imaging datasets with generation of continuous mode Mosaic Datacubes for high mass resolution visualization. An eight-fold improvement in processing time is demonstrated using a Dutch nationally available cloud service.« less
High Resolution Tissue Imaging Using the Single-probe Mass Spectrometry under Ambient Conditions
NASA Astrophysics Data System (ADS)
Rao, Wei; Pan, Ning; Yang, Zhibo
2015-06-01
Ambient mass spectrometry imaging (MSI) is an emerging field with great potential for the detailed spatial analysis of biological samples with minimal pretreatment. We have developed a miniaturized sampling and ionization device, the Single-probe, which uses in-situ surface micro-extraction to achieve high detection sensitivity and spatial resolution during MSI experiments. The Single-probe was coupled to a Thermo LTQ Orbitrap XL mass spectrometer and was able to create high spatial and high mass resolution MS images at 8 ± 2 and 8.5 μm on flat polycarbonate microscope slides and mouse kidney sections, respectively, which are among the highest resolutions available for ambient MSI techniques. Our proof-of-principle experiments indicate that the Single-probe MSI technique has the potential to obtain ambient MS images with very high spatial resolutions with minimal sample preparation, which opens the possibility for subcellular ambient tissue MSI to be performed in the future.
NASA Astrophysics Data System (ADS)
Ota, Junko; Umehara, Kensuke; Ishimaru, Naoki; Ohno, Shunsuke; Okamoto, Kentaro; Suzuki, Takanori; Shirai, Naoki; Ishida, Takayuki
2017-02-01
As the capability of high-resolution displays grows, high-resolution images are often required in Computed Tomography (CT). However, acquiring high-resolution images takes a higher radiation dose and a longer scanning time. In this study, we applied the Sparse-coding-based Super-Resolution (ScSR) method to generate high-resolution images without increasing the radiation dose. We prepared the over-complete dictionary learned the mapping between low- and highresolution patches and seek a sparse representation of each patch of the low-resolution input. These coefficients were used to generate the high-resolution output. For evaluation, 44 CT cases were used as the test dataset. We up-sampled images up to 2 or 4 times and compared the image quality of the ScSR scheme and bilinear and bicubic interpolations, which are the traditional interpolation schemes. We also compared the image quality of three learning datasets. A total of 45 CT images, 91 non-medical images, and 93 chest radiographs were used for dictionary preparation respectively. The image quality was evaluated by measuring peak signal-to-noise ratio (PSNR) and structure similarity (SSIM). The differences of PSNRs and SSIMs between the ScSR method and interpolation methods were statistically significant. Visual assessment confirmed that the ScSR method generated a high-resolution image with sharpness, whereas conventional interpolation methods generated over-smoothed images. To compare three different training datasets, there were no significance between the CT, the CXR and non-medical datasets. These results suggest that the ScSR provides a robust approach for application of up-sampling CT images and yields substantial high image quality of extended images in CT.
Ultra high spatial and temporal resolution breast imaging at 7T.
van de Bank, B L; Voogt, I J; Italiaander, M; Stehouwer, B L; Boer, V O; Luijten, P R; Klomp, D W J
2013-04-01
There is a need to obtain higher specificity in the detection of breast lesions using MRI. To address this need, Dynamic Contrast-Enhanced (DCE) MRI has been combined with other structural and functional MRI techniques. Unfortunately, owing to time constraints structural images at ultra-high spatial resolution can generally not be obtained during contrast uptake, whereas the relatively low spatial resolution of functional imaging (e.g. diffusion and perfusion) limits the detection of small lesions. To be able to increase spatial as well as temporal resolution simultaneously, the sensitivity of MR detection needs to increase as well as the ability to effectively accelerate the acquisition. The required gain in signal-to-noise ratio (SNR) can be obtained at 7T, whereas acceleration can be obtained with high-density receiver coil arrays. In this case, morphological imaging can be merged with DCE-MRI, and other functional techniques can be obtained at higher spatial resolution, and with less distortion [e.g. Diffusion Weighted Imaging (DWI)]. To test the feasibility of this concept, we developed a unilateral breast coil for 7T. It comprises a volume optimized dual-channel transmit coil combined with a 30-channel receive array coil. The high density of small coil elements enabled efficient acceleration in any direction to acquire ultra high spatial resolution MRI of close to 0.6 mm isotropic detail within a temporal resolution of 69 s, high spatial resolution MRI of 1.5 mm isotropic within an ultra high temporal resolution of 6.7 s and low distortion DWI at 7T, all validated in phantoms, healthy volunteers and a patient with a lesion in the right breast classified as Breast Imaging Reporting and Data System (BI-RADS) IV. Copyright © 2012 John Wiley & Sons, Ltd.
Van de Kamer, J B; Lagendijk, J J W
2002-05-21
SAR distributions in a healthy female adult head as a result of a radiating vertical dipole antenna (frequency 915 MHz) representing a hand-held mobile phone have been computed for three different resolutions: 2 mm, 1 mm and 0.4 mm. The extremely high resolution of 0.4 mm was obtained with our quasistatic zooming technique, which is briefly described in this paper. For an effectively transmitted power of 0.25 W, the maximum averaged SAR values in both cubic- and arbitrary-shaped volumes are, respectively, about 1.72 and 2.55 W kg(-1) for 1 g and 0.98 and 1.73 W kg(-1) for 10 g of tissue. These numbers do not vary much (<8%) for the different resolutions, indicating that SAR computations at a resolution of 2 mm are sufficiently accurate to describe the large-scale distribution. However, considering the detailed SAR pattern in the head, large differences may occur if high-resolution computations are performed rather than low-resolution ones. These deviations are caused by both increased modelling accuracy and improved anatomical description in higher resolution simulations. For example, the SAR profile across a boundary between tissues with high dielectric contrast is much more accurately described at higher resolutions. Furthermore, low-resolution dielectric geometries may suffer from loss of anatomical detail, which greatly affects small-scale SAR distributions. Thus. for strongly inhomogeneous regions high-resolution SAR modelling is an absolute necessity.
Waveform digitization for high resolution timing detectors with silicon photomultipliers
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ronzhin, A.; Albrow, M. G.; Los, S.
2012-03-01
The results of time resolution studies with silicon photomultipliers (SiPMs) read out with high bandwidth constant fraction discrimination electronics were presented earlier [1-3]. Here we describe the application of fast waveform digitization readout based on the DRS4 chip [4], a switched capacitor array (SCA) produced by the Paul Scherrer Institute, to further our goal of developing high time resolution detectors based on SiPMs. The influence of the SiPM signal shape on the time resolution was investigated. Different algorithms to obtain the best time resolution are described, and test beam results are presented.
Dual-axis confocal microscope for high-resolution in vivo imaging
Wang, Thomas D.; Mandella, Michael J.; Contag, Christopher H.; Kino, Gordon S.
2007-01-01
We describe a novel confocal microscope that uses separate low-numerical-aperture objectives with the illumination and collection axes crossed at angle θ from the midline. This architecture collects images in scattering media with high transverse and axial resolution, long working distance, large field of view, and reduced noise from scattered light. We measured transverse and axial (FWHM) resolution of 1.3 and 2.1 μm, respectively, in free space, and confirm subcellular resolution in excised esophageal mucosa. The optics may be scaled to millimeter dimensions and fiber coupled for collection of high-resolution images in vivo. PMID:12659264
Large Area Field of View for Fast Temporal Resolution Astronomy
NASA Astrophysics Data System (ADS)
Covarrubias, Ricardo A.
2018-01-01
Scientific CMOS (sCMOS) technology is especially relevant for high temporal resolution astronomy combining high resolution, large field of view with very fast frame rates, without sacrificing ultra-low noise performance. Solar Astronomy, Near Earth Object detections, Space Debris Tracking, Transient Observations or Wavefront Sensing are among the many applications this technology can be utilized. Andor Technology is currently developing the next-generation, very large area sCMOS camera with an extremely low noise, rapid frame rates, high resolution and wide dynamic range.
Current position of high-resolution MS for drug quantification in clinical & forensic toxicology.
Meyer, Markus R; Helfer, Andreas G; Maurer, Hans H
2014-08-01
This paper reviews high-resolution MS approaches published from January 2011 until March 2014 for the quantification of drugs (of abuse) and/or their metabolites in biosamples using LC-MS with time-of-flight or Orbitrap™ mass analyzers. Corresponding approaches are discussed including sample preparation and mass spectral settings. The advantages and limitations of high-resolution MS for drug quantification, as well as the demand for a certain resolution or a specific mass accuracy are also explored.
An infrared high resolution silicon immersion grating spectrometer for airborne and space missions
NASA Astrophysics Data System (ADS)
Ge, Jian; Zhao, Bo; Powell, Scott; Jiang, Peng; Uzakbaiuly, Berik; Tanner, David
2014-08-01
Broad-band infrared (IR) spectroscopy, especially at high spectral resolution, is a largely unexplored area for the far IR (FIR) and submm wavelength region due to the lack of proper grating technology to produce high resolution within the very constrained volume and weight required for space mission instruments. High resolution FIR spectroscopy is an essential tool to resolve many atomic and molecular lines to measure physical and chemical conditions and processes in the environments where galaxy, star and planets form. A silicon immersion grating (SIG), due to its over three times high dispersion over a traditional reflective grating, offers a compact and low cost design of new generation IR high resolution spectrographs for space missions. A prototype SIG high resolution spectrograph, called Florida IR Silicon immersion grating spectromeTer (FIRST), has been developed at UF and was commissioned at a 2 meter robotic telescope at Fairborn Observatory in Arizona. The SIG with 54.74 degree blaze angle, 16.1 l/mm groove density, and 50x86 mm2 grating area has produced R=50,000 in FIRST. The 1.4-1.8 um wavelength region is completely covered in a single exposure with a 2kx2k H2RG IR array. The on-sky performance meets the science requirements for ground-based high resolution spectroscopy. Further studies show that this kind of SIG spectrometer with an airborne 2m class telescope such as SOFIA can offer highly sensitive spectroscopy with R~20,000-30,000 at 20 to 55 microns. Details about the on-sky measurement performance of the FIRST prototype SIG spectrometer and its predicted performance with the SOFIA 2.4m telescope are introduced.
High-Resolution of Electron Microscopy of Montmorillonite and Montmorillonite/Epoxy Nanocomposites
2005-01-01
AFRL-ML-WP-TP-2006-464 HIGH-RESOLUTION OF ELECTRON MICROSCOPY OF MONTMORILLONITE AND MONTMORILLONITE /EPOXY NANOCOMPOSITES Lawrence F...HIGH-RESOLUTION OF ELECTRON MICROSCOPY OF MONTMORILLONITE AND MONTMORILLONITE /EPOXY NANOCOMPOSITES 5c. PROGRAM ELEMENT NUMBER 62102F 5d...transmission electron microscopy the structure and morphology of montmorillonite (MMT), a material of current interest for use in polymer nanocomposites, was
High resolution scintillation detector with semiconductor readout
Levin, Craig S.; Hoffman, Edward J.
2000-01-01
A novel high resolution scintillation detector array for use in radiation imaging such as high resolution Positron Emission Tomography (PET) which comprises one or more parallelepiped crystals with at least one long surface of each crystal being in intimate contact with a semiconductor photodetector such that photons generated within each crystal by gamma radiation passing therethrough is detected by the photodetector paired therewith.
High-resolution ground-based spectroscopy: where and how ?
NASA Astrophysics Data System (ADS)
Pallavicini, R.
2002-07-01
An overview is presented of high-resolution optical spectrographs in operation or under development at large telescopes, with emphasis on those facilities best suited for the study of late-type stars and stellar surface inhomogeneities. Plans for the development of new high-resolution spectroscopic instruments are discussed with emphasis on the ICE spectrograph for the PEPSI spectropolarimeter at the LBT.
Microdome-gooved Gd(2)O(2)S:Tb scintillator for flexible and high resolution digital radiography.
Jung, Phill Gu; Lee, Chi Hoon; Bae, Kong Myeong; Lee, Jae Min; Lee, Sang Min; Lim, Chang Hwy; Yun, Seungman; Kim, Ho Kyung; Ko, Jong Soo
2010-07-05
A flexible microdome-grooved Gd(2)O(2)S:Tb scintillator is simulated, fabricated, and characterized for digital radiography applications. According to Monte Carlo simulation results, the dome-grooved structure has a high spatial resolution, which is verified by X-ray image performance of the scintillator. The proposed scintillator has lower X-ray sensitivity than a nonstructured scintillator but almost two times higher spatial resolution at high spatial frequency. Through evaluation of the X-ray performance of the fabricated scintillators, we confirm that the microdome-grooved scintillator can be applied to next-generation flexible digital radiography systems requiring high spatial resolution.
Beyer, Hannes; Wagner, Tino; Stemmer, Andreas
2016-01-01
Frequency-modulation atomic force microscopy has turned into a well-established method to obtain atomic resolution on flat surfaces, but is often limited to ultra-high vacuum conditions and cryogenic temperatures. Measurements under ambient conditions are influenced by variations of the dew point and thin water layers present on practically every surface, complicating stable imaging with high resolution. We demonstrate high-resolution imaging in air using a length-extension resonator operating at small amplitudes. An additional slow feedback compensates for changes in the free resonance frequency, allowing stable imaging over a long period of time with changing environmental conditions.
Zook, James D.; Molugu, Trivikram R.; Jacobsen, Neil E.; Lin, Guangxin; Soll, Jürgen; Cherry, Brian R.; Brown, Michael F.; Fromme, Petra
2013-01-01
Solving high-resolution structures for membrane proteins continues to be a daunting challenge in the structural biology community. In this study we report our high-resolution NMR results for a transmembrane protein, outer envelope protein of molar mass 16 kDa (OEP16), an amino acid transporter from the outer membrane of chloroplasts. Three-dimensional, high-resolution NMR experiments on the 13C, 15N, 2H-triply-labeled protein were used to assign protein backbone resonances and to obtain secondary structure information. The results yield over 95% assignment of N, HN, CO, Cα, and Cβ chemical shifts, which is essential for obtaining a high resolution structure from NMR data. Chemical shift analysis from the assignment data reveals experimental evidence for the first time on the location of the secondary structure elements on a per residue basis. In addition T 1Z and T2 relaxation experiments were performed in order to better understand the protein dynamics. Arginine titration experiments yield an insight into the amino acid residues responsible for protein transporter function. The results provide the necessary basis for high-resolution structural determination of this important plant membrane protein. PMID:24205117
The implementation of sea ice model on a regional high-resolution scale
NASA Astrophysics Data System (ADS)
Prasad, Siva; Zakharov, Igor; Bobby, Pradeep; McGuire, Peter
2015-09-01
The availability of high-resolution atmospheric/ocean forecast models, satellite data and access to high-performance computing clusters have provided capability to build high-resolution models for regional ice condition simulation. The paper describes the implementation of the Los Alamos sea ice model (CICE) on a regional scale at high resolution. The advantage of the model is its ability to include oceanographic parameters (e.g., currents) to provide accurate results. The sea ice simulation was performed over Baffin Bay and the Labrador Sea to retrieve important parameters such as ice concentration, thickness, ridging, and drift. Two different forcing models, one with low resolution and another with a high resolution, were used for the estimation of sensitivity of model results. Sea ice behavior over 7 years was simulated to analyze ice formation, melting, and conditions in the region. Validation was based on comparing model results with remote sensing data. The simulated ice concentration correlated well with Advanced Microwave Scanning Radiometer for EOS (AMSR-E) and Ocean and Sea Ice Satellite Application Facility (OSI-SAF) data. Visual comparison of ice thickness trends estimated from the Soil Moisture and Ocean Salinity satellite (SMOS) agreed with the simulation for year 2010-2011.
Fei, Chunlong; Chiu, Chi Tat; Chen, Xiaoyang; Chen, Zeyu; Ma, Jianguo; Zhu, Benpeng; Shung, K. Kirk; Zhou, Qifa
2016-01-01
High resolution ultrasonic imaging requires high frequency wide band ultrasonic transducers, which produce short pulses and highly focused beam. However, currently the frequency of ultrasonic transducers is limited to below 100 MHz, mainly because of the challenge in precise control of fabrication parameters. This paper reports the design, fabrication, and characterization of sensitive broadband lithium niobate (LiNbO3) single element ultrasonic transducers in the range of 100–300 MHz, as well as their applications in high resolution imaging. All transducers were built for an f-number close to 1.0, which was achieved by press-focusing the piezoelectric layer into a spherical curvature. Characterization results demonstrated their high sensitivity and a −6 dB bandwidth greater than 40%. Resolutions better than 6.4 μm in the lateral direction and 6.2 μm in the axial direction were achieved by scanning a 4 μm tungsten wire target. Ultrasonic biomicroscopy images of zebrafish eyes were obtained with these transducers which demonstrate the feasibility of high resolution imaging with a performance comparable to optical resolution. PMID:27329379
BLIPPED (BLIpped Pure Phase EncoDing) high resolution MRI with low amplitude gradients
NASA Astrophysics Data System (ADS)
Xiao, Dan; Balcom, Bruce J.
2017-12-01
MRI image resolution is proportional to the maximum k-space value, i.e. the temporal integral of the magnetic field gradient. High resolution imaging usually requires high gradient amplitudes and/or long spatial encoding times. Special gradient hardware is often required for high amplitudes and fast switching. We propose a high resolution imaging sequence that employs low amplitude gradients. This method was inspired by the previously proposed PEPI (π Echo Planar Imaging) sequence, which replaced EPI gradient reversals with multiple RF refocusing pulses. It has been shown that when the refocusing RF pulse is of high quality, i.e. sufficiently close to 180°, the magnetization phase introduced by the spatial encoding magnetic field gradient can be preserved and transferred to the following echo signal without phase rewinding. This phase encoding scheme requires blipped gradients that are identical for each echo, with low and constant amplitude, providing opportunities for high resolution imaging. We now extend the sequence to 3D pure phase encoding with low amplitude gradients. The method is compared with the Hybrid-SESPI (Spin Echo Single Point Imaging) technique to demonstrate the advantages in terms of low gradient duty cycle, compensation of concomitant magnetic field effects and minimal echo spacing, which lead to superior image quality and high resolution. The 3D imaging method was then applied with a parallel plate resonator RF probe, achieving a nominal spatial resolution of 17 μm in one dimension in the 3D image, requiring a maximum gradient amplitude of only 5.8 Gauss/cm.
High-resolution high-efficiency multilayer Fresnel zone plates for soft and hard x-rays
NASA Astrophysics Data System (ADS)
Sanli, Umut T.; Keskinbora, Kahraman; Gregorczyk, Keith; Leister, Jonas; Teeny, Nicolas; Grévent, Corinne; Knez, Mato; Schütz, Gisela
2015-09-01
X-ray microscopy enables high spatial resolutions, high penetration depths and characterization of a broad range of materials. Calculations show that nanometer range resolution is achievable in the hard X-ray regime by using Fresnel zone plates (FZPs) if certain conditions are satisfied. However, this requires, among other things, aspect ratios of several thousands. The multilayer (ML) type FZPs, having virtually unlimited aspect ratios, are strong candidates to achieve single nanometer resolutions. Our research is focused on the fabrication of ML-FZPs which encompasses deposition of multilayers over a glass fiber via the atomic layer deposition (ALD), which is subsequently sliced in the optimum thickness for the X-ray energy by a focused ion beam (FIB). We recently achieved aberration free imaging by resolving 21 nm features with an efficiency of up to 12.5 %, the highest imaging resolution achieved by an ML-FZP. We also showed efficient focusing of 7.9 keV X-rays down to 30 nm focal spot size (FWHM). For resolutions below ~10 nm, efficiencies would decrease significantly due to wave coupling effects. To compensate this effect high efficiency, low stress materials have to be researched, as lower intrinsic stresses will allow fabrication of larger FZPs with higher number of zones, leading to high light intensity at the focus. As a first step we fabricated an ML-FZP with a diameter of 62 μm, an outermost zone width of 12 nm and 452 active zones. Further strategies for fabrication of high resolution high efficiency multilayer FZPs will also be discussed.
Photoionization Rate of Atomic Oxygen
NASA Astrophysics Data System (ADS)
Meier, R. R.; McLaughlin, B. M.; Warren, H. P.; Bishop, J.
2006-05-01
Accurate knowledge of the photoionization rate of atomic oxygen is important for the study and understanding of the ionospheres and emission processes of terrestrial, planetary, and cometary atmospheres. Past calculations of the photoionization rate have been carried out at various spectral resolutions, but none were at sufficiently high resolution to accommodate accidental resonances between solar emission lines and highly structured auto-ionization features in the photoionization cross section. A new version of the NRLEUV solar spectral irradiance model (at solar minimum) and a new model of the O photoionization cross section enable calculations at very high spectral resolution. We find unattenuated photoionization rates computed at 0.001 nm resolution are larger than those at moderate resolution (0.1 nm) by amounts approaching 20%. Allowing for attenuation in the terrestrial atmosphere, we find differences in photoionization rates computed at high and moderate resolution to vary with altitude, especially below 200 km where deviations of plus or minus 20% occur between the two cases.
High spatial resolution compressed sensing (HSPARSE) functional MRI.
Fang, Zhongnan; Van Le, Nguyen; Choy, ManKin; Lee, Jin Hyung
2016-08-01
To propose a novel compressed sensing (CS) high spatial resolution functional MRI (fMRI) method and demonstrate the advantages and limitations of using CS for high spatial resolution fMRI. A randomly undersampled variable density spiral trajectory enabling an acceleration factor of 5.3 was designed with a balanced steady state free precession sequence to achieve high spatial resolution data acquisition. A modified k-t SPARSE method was then implemented and applied with a strategy to optimize regularization parameters for consistent, high quality CS reconstruction. The proposed method improves spatial resolution by six-fold with 12 to 47% contrast-to-noise ratio (CNR), 33 to 117% F-value improvement and maintains the same temporal resolution. It also achieves high sensitivity of 69 to 99% compared the original ground-truth, small false positive rate of less than 0.05 and low hemodynamic response function distortion across a wide range of CNRs. The proposed method is robust to physiological noise and enables detection of layer-specific activities in vivo, which cannot be resolved using the highest spatial resolution Nyquist acquisition. The proposed method enables high spatial resolution fMRI that can resolve layer-specific brain activity and demonstrates the significant improvement that CS can bring to high spatial resolution fMRI. Magn Reson Med 76:440-455, 2016. © 2015 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. © 2015 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.
Meza, Daphne; Wang, Danni; Wang, Yu; Borwege, Sabine; Sanai, Nader; Liu, Jonathan T C
2015-04-01
Fluorescence image-guided surgery (FIGS), with contrast provided by 5-ALA-induced PpIX, has been shown to enable a higher extent of resection of high-grade gliomas. However, conventional FIGS with low-power microscopy lacks the sensitivity to aid in low-grade glioma (LGG) resection because PpIX signal is weak and sparse in such tissues. Intraoperative high-resolution microscopy of PpIX fluorescence has been proposed as a method to guide LGG resection, where sub-cellular resolution allows for the visualization of sparse and punctate mitochondrial PpIX production in tumor cells. Here, we assess the performance of three potentially portable high-resolution microscopy techniques that may be used for the intraoperative imaging of human LGG tissue samples with PpIX contrast: high-resolution fiber-optic microscopy (HRFM), high-resolution wide-field microscopy (WFM), and dual-axis confocal (DAC) microscopy. Thick unsectioned human LGG tissue samples (n = 7) with 5-ALA-induced PpIX contrast were imaged using three imaging techniques (HRFM, WFM, DAC). The average signal-to-background ratio (SBR) was then calculated for each imaging modality (5 images per tissue, per modality). HRFM provides the ease of use and portability of a flexible fiber bundle, and is simple and inexpensive to build. However, in most cases (6/7), HRFM is not capable of detecting PpIX signal from LGGs due to high autofluorescence, generated by the fiber bundle under laser illumination at 405 nm, which overwhelms the PpIX signal and impedes its visualization. WFM is a camera-based method possessing high lateral resolution but poor axial resolution, resulting in sub-optimal image contrast. Consistent successful detection of PpIX signal throughout our human LGG tissue samples (n = 7), with an acceptable image contrast (SBR >2), was only achieved using DAC microscopy, which offers superior image resolution and contrast that is comparable to histology, but requires a laser-scanning mechanism to achieve optical sectioning. © 2015 Wiley Periodicals, Inc.
Refinement procedure for the image alignment in high-resolution electron tomography.
Houben, L; Bar Sadan, M
2011-01-01
High-resolution electron tomography from a tilt series of transmission electron microscopy images requires an accurate image alignment procedure in order to maximise the resolution of the tomogram. This is the case in particular for ultra-high resolution where even very small misalignments between individual images can dramatically reduce the fidelity of the resultant reconstruction. A tomographic-reconstruction based and marker-free method is proposed, which uses an iterative optimisation of the tomogram resolution. The method utilises a search algorithm that maximises the contrast in tomogram sub-volumes. Unlike conventional cross-correlation analysis it provides the required correlation over a large tilt angle separation and guarantees a consistent alignment of images for the full range of object tilt angles. An assessment based on experimental reconstructions shows that the marker-free procedure is competitive to the reference of marker-based procedures at lower resolution and yields sub-pixel accuracy even for simulated high-resolution data. Copyright © 2011 Elsevier B.V. All rights reserved.
Transmission of digital images within the NTSC analog format
Nickel, George H.
2004-06-15
HDTV and NTSC compatible image communication is done in a single NTSC channel bandwidth. Luminance and chrominance image data of a scene to be transmitted is obtained. The image data is quantized and digitally encoded to form digital image data in HDTV transmission format having low-resolution terms and high-resolution terms. The low-resolution digital image data terms are transformed to a voltage signal corresponding to NTSC color subcarrier modulation with retrace blanking and color bursts to form a NTSC video signal. The NTSC video signal and the high-resolution digital image data terms are then transmitted in a composite NTSC video transmission. In a NTSC receiver, the NTSC video signal is processed directly to display the scene. In a HDTV receiver, the NTSC video signal is processed to invert the color subcarrier modulation to recover the low-resolution terms, where the recovered low-resolution terms are combined with the high-resolution terms to reconstruct the scene in a high definition format.
NASA Technical Reports Server (NTRS)
Putman, William P.
2012-01-01
Using a high-resolution non-hydrostatic version of GEOS-5 with the cubed-sphere finite-volume dynamical core, the impact of spatial and temporal resolution on cloud properties will be evaluated. There are indications from examining convective cluster development in high resolution GEOS-5 forecasts that the temporal resolution within the model may playas significant a role as horizontal resolution. Comparing modeled convective cloud clusters versus satellite observations of brightness temperature, we have found that improved. temporal resolution in GEOS-S accounts for a significant portion of the improvements in the statistical distribution of convective cloud clusters. Using satellite simulators in GEOS-S we will compare the cloud optical properties of GEOS-S at various spatial and temporal resolutions with those observed from MODIS. The potential impact of these results on tropical cyclone formation and intensity will be examined as well.
Single-shot and single-sensor high/super-resolution microwave imaging based on metasurface
Wang, Libo; Li, Lianlin; Li, Yunbo; Zhang, Hao Chi; Cui, Tie Jun
2016-01-01
Real-time high-resolution (including super-resolution) imaging with low-cost hardware is a long sought-after goal in various imaging applications. Here, we propose broadband single-shot and single-sensor high-/super-resolution imaging by using a spatio-temporal dispersive metasurface and an imaging reconstruction algorithm. The metasurface with spatio-temporal dispersive property ensures the feasibility of the single-shot and single-sensor imager for super- and high-resolution imaging, since it can convert efficiently the detailed spatial information of the probed object into one-dimensional time- or frequency-dependent signal acquired by a single sensor fixed in the far-field region. The imaging quality can be improved by applying a feature-enhanced reconstruction algorithm in post-processing, and the desired imaging resolution is related to the distance between the object and metasurface. When the object is placed in the vicinity of the metasurface, the super-resolution imaging can be realized. The proposed imaging methodology provides a unique means to perform real-time data acquisition, high-/super-resolution images without employing expensive hardware (e.g. mechanical scanner, antenna array, etc.). We expect that this methodology could make potential breakthroughs in the areas of microwave, terahertz, optical, and even ultrasound imaging. PMID:27246668
NASA Astrophysics Data System (ADS)
Quiers, M.; Perrette, Y.; Etienne, D.; Develle, A. L.; Jacq, K.
2017-12-01
The use of organic proxies increases in paleoenvironmental reconstructions from natural archives. Major advances have been achieved by the development of new highly informative molecular proxies usually linked to specific compounds. While studies focused on targeted compounds, offering a high information degree, advances on bulk organic matter are limited. However, this bulk is the main contributor to carbon cycle and has been shown to be a driver of many mineral or organic compounds transfer and record. Development of target proxies need complementary information on bulk organic matter to understand biases link to controlling factors or analytical methods, and provide a robust interpretation. Fluorescence methods have often been employed to characterize and quantify organic matter. However, these technics are mainly developed for liquid samples, inducing material and resolution loss when working on natural archives (either stalagmite or sediments). High-resolution solid phase fluorescence (SPF) was developed on speleothems. This method allows now to analyse organic matter quality and quantity if procedure to constrain the optical density are adopted. In fact, a calibration method using liquid phase fluorescence (LPF) was developed for speleothem, allowing to quantify organic carbon at high-resolution. We report here an application of such a procedure SPF/LPF measurements on lake sediments. In order to avoid sediment matrix effects on the fluorescence signal, a calibration using LPF measurements was realised. First results using this method provided organic matter quality record of different organic matter compounds (humic-like, protein-like and chlorophylle-like compounds) at high resolution for the sediment core. High resolution organic matter fluxes are obtained in a second time, applying pragmatic chemometrics model (non linear models, partial least square models) on high resolution fluorescence data. SPF method can be considered as a promising tool for high resolution record on organic matter quality and quantity. Potential application of this method will be evocated (lake ecosystem dynamic, changes in trophic levels)
Bibliography of In-House and Contract Reports. Supplement 16
1989-10-01
Differences from ETL-71-CR-10 1971 Grav,t% and Gravity Gradients 54 TiLE REPORT NO. YEAR Determination of Level Sensitivity (Field ETL-RN-74-4 1974...Data Base Study, Phase II ETL-0360 1984 High Resolution Optical Power Spectrum Analyzer ETL-0127 1978 High Resolution Orthophoto Output Table (HIROOT...AD 856 731L 1969 High Resolution Orthophoto Output Table ETL-ETR-72-3 1972 High Speed Disc Memory and a Color Image AD 878 975L 1970 Display for a
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ogura, Toshihiko, E-mail: t-ogura@aist.go.jp
Scanning electron microscopy (SEM) has been widely used to examine biological specimens of bacteria, viruses and proteins. Until now, atmospheric and/or wet biological specimens have been examined using various atmospheric holders or special equipment involving SEM. Unfortunately, they undergo heavy radiation damage by the direct electron beam. In addition, images of unstained biological samples in water yield poor contrast. We recently developed a new analytical technology involving a frequency transmission electric-field (FTE) method based on thermionic SEM. This method is suitable for high-contrast imaging of unstained biological specimens. Our aim was to optimise the method. Here we describe a high-resolutionmore » FTE system based on field-emission SEM; it allows for imaging and nanoscale examination of various biological specimens in water without radiation damage. The spatial resolution is 8 nm, which is higher than 41 nm of the existing FTE system. Our new method can be easily utilised for examination of unstained biological specimens including bacteria, viruses and protein complexes. Furthermore, our high-resolution FTE system can be used for diverse liquid samples across a broad range of scientific fields, e.g. nanoparticles, nanotubes and organic and catalytic materials. - Highlights: • We developed a high-resolution frequency transmission electric-field (FTE) system. • High-resolution FTE system is introduced in the field-emission SEM. • The spatial resolution of high-resolution FTE method is 8 nm. • High-resolution FTE system enables observation of the intact IgM particles in water.« less
NASA Astrophysics Data System (ADS)
Hong, Liang
2013-10-01
The availability of high spatial resolution remote sensing data provides new opportunities for urban land-cover classification. More geometric details can be observed in the high resolution remote sensing image, Also Ground objects in the high resolution remote sensing image have displayed rich texture, structure, shape and hierarchical semantic characters. More landscape elements are represented by a small group of pixels. Recently years, the an object-based remote sensing analysis methodology is widely accepted and applied in high resolution remote sensing image processing. The classification method based on Geo-ontology and conditional random fields is presented in this paper. The proposed method is made up of four blocks: (1) the hierarchical ground objects semantic framework is constructed based on geoontology; (2) segmentation by mean-shift algorithm, which image objects are generated. And the mean-shift method is to get boundary preserved and spectrally homogeneous over-segmentation regions ;(3) the relations between the hierarchical ground objects semantic and over-segmentation regions are defined based on conditional random fields framework ;(4) the hierarchical classification results are obtained based on geo-ontology and conditional random fields. Finally, high-resolution remote sensed image data -GeoEye, is used to testify the performance of the presented method. And the experimental results have shown the superiority of this method to the eCognition method both on the effectively and accuracy, which implies it is suitable for the classification of high resolution remote sensing image.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhu, Fan, E-mail: zf5016@126.com; Center of Ultra-precision Optoelectronic Instrument Engineering, Harbin Institute of Technology, Harbin 150080; Tan, Xinran
An autocollimation (AC) setup with ultra-high resolution and stability for micro-angle measurement is presented. The telephoto objective, which is characterized in long focal length at a compact structure size, and the optical enlargement unit, which can magnify the image displacement to improve its measurement resolution and accuracy, are used to obtain an ultra-high measurement resolution of the AC. The common-path beam drift compensation is used to suppress the drift of measurement results, which is evident in the high-resolution AC, thus to obtain a high measurement stability. Experimental results indicate that an effective resolution of better than 0.0005 arc sec (2.42more » nrad) over a measurement range of ±30 arc sec and a 2-h stability of 0.0061 arc sec (29.57 nrad) can be achieved.« less
NASA Astrophysics Data System (ADS)
Zhang, Kai; Zhu, Yongtian; Hu, Zhongwen
2016-08-01
The Maunakea Spectroscopic Explorer (MSE) project will transform the CFHT 3.6m optical telescope into a 10m class dedicated multi-object spectroscopic facility, with an ability to simultaneously measure thousands of objects with a spectral resolution range spanning 2,000 to 40,000. MSE will develop two spectrographic facilities to meet the science requirements. These are respectively, the Low/Medium Resolution spectrographs (LMRS) and High Resolution spectrographs (HRS). Multi-object high resolution spectrographs with total of 1,156 fibers is a big challenge, one that has never been attempted for a 10m class telescope. To date, most spectral survey facilities work in single order low/medium resolution mode, and only a few Wide Field Spectrographs (WFS) provide a cross-dispersion high resolution mode with a limited number of orders. Nanjing Institute of Astronomical Optics and Technology (NIAOT) propose a conceptual design with the use of novel image slicer arrays and single order immersed Volume Phase Holographic (VPH) grating for the MSE multi-object high resolution spectrographs. The conceptual scheme contains six identical fiber-link spectrographs, each of which simultaneously covers three restricted bands (λ/30, λ/30, λ/15) in the optical regime, with spectral resolution of 40,000 in Blue/Visible bands (400nm / 490nm) and 20,000 in Red band (650nm). The details of the design is presented in this paper.
High Spatial Resolution Commercial Satellite Imaging Product Characterization
NASA Technical Reports Server (NTRS)
Ryan, Robert E.; Pagnutti, Mary; Blonski, Slawomir; Ross, Kenton W.; Stnaley, Thomas
2005-01-01
NASA Stennis Space Center's Remote Sensing group has been characterizing privately owned high spatial resolution multispectral imaging systems, such as IKONOS, QuickBird, and OrbView-3. Natural and man made targets were used for spatial resolution, radiometric, and geopositional characterizations. Higher spatial resolution also presents significant adjacency effects for accurate reliable radiometry.
The investigation of classification methods of high-resolution imagery
Tracey S. Frescino; Gretchen G. Moisen; Larry DeBlander; Michel Guerin
2007-01-01
As remote-sensing technology advances, high-resolution imagery, such as Quickbird and photography from the National Agriculture Imagery Program (NAIP), is becoming more readily available for use in forestry applications. Quickbird imagery is currently the highest resolution imagery commercially available. It consists of 2.44-m (8-ft) resolution multispectral bands...
Boyle, Sarah A; Kennedy, Christina M; Torres, Julio; Colman, Karen; Pérez-Estigarribia, Pastor E; de la Sancha, Noé U
2014-01-01
Technological advances and increasing availability of high-resolution satellite imagery offer the potential for more accurate land cover classifications and pattern analyses, which could greatly improve the detection and quantification of land cover change for conservation. Such remotely-sensed products, however, are often expensive and difficult to acquire, which prohibits or reduces their use. We tested whether imagery of high spatial resolution (≤5 m) differs from lower-resolution imagery (≥30 m) in performance and extent of use for conservation applications. To assess performance, we classified land cover in a heterogeneous region of Interior Atlantic Forest in Paraguay, which has undergone recent and dramatic human-induced habitat loss and fragmentation. We used 4 m multispectral IKONOS and 30 m multispectral Landsat imagery and determined the extent to which resolution influenced the delineation of land cover classes and patch-level metrics. Higher-resolution imagery more accurately delineated cover classes, identified smaller patches, retained patch shape, and detected narrower, linear patches. To assess extent of use, we surveyed three conservation journals (Biological Conservation, Biotropica, Conservation Biology) and found limited application of high-resolution imagery in research, with only 26.8% of land cover studies analyzing satellite imagery, and of these studies only 10.4% used imagery ≤5 m resolution. Our results suggest that high-resolution imagery is warranted yet under-utilized in conservation research, but is needed to adequately monitor and evaluate forest loss and conversion, and to delineate potentially important stepping-stone fragments that may serve as corridors in a human-modified landscape. Greater access to low-cost, multiband, high-resolution satellite imagery would therefore greatly facilitate conservation management and decision-making.
Satellite image time series simulation for environmental monitoring
NASA Astrophysics Data System (ADS)
Guo, Tao
2014-11-01
The performance of environmental monitoring heavily depends on the availability of consecutive observation data and it turns out an increasing demand in remote sensing community for satellite image data in the sufficient resolution with respect to both spatial and temporal requirements, which appear to be conflictive and hard to tune tradeoffs. Multiple constellations could be a solution if without concerning cost, and thus it is so far interesting but very challenging to develop a method which can simultaneously improve both spatial and temporal details. There are some research efforts to deal with the problem from various aspects, a type of approaches is to enhance the spatial resolution using techniques of super resolution, pan-sharpen etc. which can produce good visual effects, but mostly cannot preserve spectral signatures and result in losing analytical value. Another type is to fill temporal frequency gaps by adopting time interpolation, which actually doesn't increase informative context at all. In this paper we presented a novel method to generate satellite images in higher spatial and temporal details, which further enables satellite image time series simulation. Our method starts with a pair of high-low resolution data set, and then a spatial registration is done by introducing LDA model to map high and low resolution pixels correspondingly. Afterwards, temporal change information is captured through a comparison of low resolution time series data, and the temporal change is then projected onto high resolution data plane and assigned to each high resolution pixel referring the predefined temporal change patterns of each type of ground objects to generate a simulated high resolution data. A preliminary experiment shows that our method can simulate a high resolution data with a good accuracy. We consider the contribution of our method is to enable timely monitoring of temporal changes through analysis of low resolution images time series only, and usage of costly high resolution data can be reduced as much as possible, and it presents an efficient solution with great cost performance to build up an economically operational monitoring service for environment, agriculture, forest, land use investigation, and other applications.
NASA Astrophysics Data System (ADS)
Vrieling, Anton; Skidmore, Andrew K.; Wang, Tiejun; Meroni, Michele; Ens, Bruno J.; Oosterbeek, Kees; O'Connor, Brian; Darvishzadeh, Roshanak; Heurich, Marco; Shepherd, Anita; Paganini, Marc
2017-07-01
Vegetation indices derived from satellite image time series have been extensively used to estimate the timing of phenological events like season onset. Medium spatial resolution (≥250 m) satellite sensors with daily revisit capability are typically employed for this purpose. In recent years, phenology is being retrieved at higher resolution (≤30 m) in response to increasing availability of high-resolution satellite data. To overcome the reduced acquisition frequency of such data, previous attempts involved fusion between high- and medium-resolution data, or combinations of multi-year acquisitions in a single phenological reconstruction. The objectives of this study are to demonstrate that phenological parameters can now be retrieved from single-season high-resolution time series, and to compare these retrievals against those derived from multi-year high-resolution and single-season medium-resolution satellite data. The study focuses on the island of Schiermonnikoog, the Netherlands, which comprises a highly-dynamic saltmarsh, dune vegetation, and agricultural land. Combining NDVI series derived from atmospherically-corrected images from RapidEye (5 m-resolution) and the SPOT5 Take5 experiment (10m-resolution) acquired between March and August 2015, phenological parameters were estimated using a function fitting approach. We then compared results with phenology retrieved from four years of 30 m Landsat 8 OLI data, and single-year 100 m Proba-V and 250 m MODIS temporal composites of the same period. Retrieved phenological parameters from combined RapidEye/SPOT5 displayed spatially consistent results and a large spatial variability, providing complementary information to existing vegetation community maps. Retrievals that combined four years of Landsat observations into a single synthetic year were affected by the inclusion of years with warmer spring temperatures, whereas adjustment of the average phenology to 2015 observations was only feasible for a few pixels due to cloud cover around phenological transition dates. The Proba-V and MODIS phenology retrievals scaled poorly relative to their high-resolution equivalents, indicating that medium-resolution phenology retrievals need to be interpreted with care, particularly in landscapes with fine-scale land cover variability.
NASA Astrophysics Data System (ADS)
Krishnamurthy, Lakshmi; Muñoz, Ángel G.; Vecchi, Gabriel A.; Msadek, Rym; Wittenberg, Andrew T.; Stern, Bill; Gudgel, Rich; Zeng, Fanrong
2018-05-01
The Caribbean low-level jet (CLLJ) is an important component of the atmospheric circulation over the Intra-Americas Sea (IAS) which impacts the weather and climate both locally and remotely. It influences the rainfall variability in the Caribbean, Central America, northern South America, the tropical Pacific and the continental Unites States through the transport of moisture. We make use of high-resolution coupled and uncoupled models from the Geophysical Fluid Dynamics Laboratory (GFDL) to investigate the simulation of the CLLJ and its teleconnections and further compare with low-resolution models. The high-resolution coupled model FLOR shows improvements in the simulation of the CLLJ and its teleconnections with rainfall and SST over the IAS compared to the low-resolution coupled model CM2.1. The CLLJ is better represented in uncoupled models (AM2.1 and AM2.5) forced with observed sea-surface temperatures (SSTs), emphasizing the role of SSTs in the simulation of the CLLJ. Further, we determine the forecast skill for observed rainfall using both high- and low-resolution predictions of rainfall and SSTs for the July-August-September season. We determine the role of statistical correction of model biases, coupling and horizontal resolution on the forecast skill. Statistical correction dramatically improves area-averaged forecast skill. But the analysis of spatial distribution in skill indicates that the improvement in skill after statistical correction is region dependent. Forecast skill is sensitive to coupling in parts of the Caribbean, Central and northern South America, and it is mostly insensitive over North America. Comparison of forecast skill between high and low-resolution coupled models does not show any dramatic difference. However, uncoupled models show improvement in the area-averaged skill in the high-resolution atmospheric model compared to lower resolution model. Understanding and improving the forecast skill over the IAS has important implications for highly vulnerable nations in the region.
NASA Astrophysics Data System (ADS)
Gasmi, Taieb
2018-04-01
An extra-cavity CO2-TEA laser pulse clipper for high spatial resolution atmospheric monitoring is presented. The clipper uses pulsed high voltageto facilitate the breakdown of the gas within the clipper cell. Complete extinction of the nitrogen tail, that degrades the range resolution of LIDARS, is obtained at pressures from 375 up to 1500 Torr for nitrogen and argon gases whereas an attenuation coefficient of almost 102 is achieved for helium. Excellent energy stability and pulse width repeatability were achieved using high voltage pre-ionized gas technique.
High-resolution ultrashort echo time (UTE) imaging on human knee with AWSOS sequence at 3.0 T.
Qian, Yongxian; Williams, Ashley A; Chu, Constance R; Boada, Fernando E
2012-01-01
To demonstrate the technical feasibility of high-resolution (0.28-0.14 mm) ultrashort echo time (UTE) imaging on human knee at 3T with the acquisition-weighted stack of spirals (AWSOS) sequence. Nine human subjects were scanned on a 3T MRI scanner with an 8-channel knee coil using the AWSOS sequence and isocenter positioning plus manual shimming. High-resolution UTE images were obtained on the subject knees at TE = 0.6 msec with total acquisition time of 5.12 minutes for 60 slices at an in-plane resolution of 0.28 mm and 10.24 minutes for 40 slices at an in-plane resolution of 0.14 mm. Isocenter positioning, manual shimming, and the 8-channel array coil helped minimize image distortion and achieve high signal-to-noise ratio (SNR). It is technically feasible on a clinical 3T MRI scanner to perform UTE imaging on human knee at very high spatial resolutions (0.28-0.14 mm) within reasonable scan time (5-10 min) using the AWSOS sequence. Copyright © 2011 Wiley Periodicals, Inc.
The impact of high-resolution ultrasound in the differential diagnosis of non-hemolytic jaundice.
Rauh, Peter; Neye, Holger; Mönkemüller, Klaus; Malfertheiner, Peter; Rickes, Steffen
2010-12-01
Because jaundice is a common reason for hospital admission. A fast and correct differential diagnosis is very important to increase treatment efficacy. The aim of our study was to evaluate the impact of the high-resolution ultrasound in this kind of clinical setting. In a prospective study we included 30 patients and we divided them in patients with extrahepatic jaundice and patients with intrahepatic jaundice. We observed a high accuracy of the high-resolution sonography, with a sensitivity of 95% and a specificity of 100% for extrahepatic jaundice, and a sensitivity of 100% and a specificity of 95% for intrahepatic jaundice. We conclude that the high-resolution ultrasound should be used in the very beginning of the diagnostic algorithm for the evaluation of patients with unclear jaundice.
X-ray Optics Development at MSFC
NASA Technical Reports Server (NTRS)
Sharma, Dharma P.
2017-01-01
Development of high resolution focusing telescopes has led to a tremendous leap in sensitivity, revolutionizing observational X-ray astronomy. High sensitivity and high spatial resolution X-ray observations have been possible due to use of grazing incidence optics (paraboloid/hyperboloid) coupled with high spatial resolution and high efficiency detectors/imagers. The best X-ray telescope flown so far is mounted onboard Chandra observatory launched on July 23,1999. The telescope has a spatial resolution of 0.5 arc seconds with compatible imaging instruments in the energy range of 0.1 to 10 keV. The Chandra observatory has been responsible for a large number of discoveries and has provided X-ray insights on a large number of celestial objects including stars, supernova remnants, pulsars, magnetars, black holes, active galactic nuclei, galaxies, clusters and our own solar system.
NASA Astrophysics Data System (ADS)
Cecilia, A.; Rack, A.; Douissard, P.-A.; Martin, T.; Dos Santos Rolo, T.; Vagovič, P.; Hamann, E.; van de Kamp, T.; Riedel, A.; Fiederle, M.; Baumbach, T.
2011-08-01
Within the project ScinTAX of the 6th framework program (FP6) of the European Commission (SCINTAX—STRP 033 427) we have developed a new thin single crystal scintillator for high-resolution X-ray imaging. The scintillator is based on a Tb-doped Lu2SiO5 (LSO) film epitaxially grown on an adapted substrate. The high density, effective atomic number and light yield of the scintillating LSO significantly improves the efficiency of the X-ray imaging detectors currently used in synchrotron micro-imaging applications. In this work we present the characterization of the scintillating LSO films in terms of their spatial resolution performance and we provide two examples of high spatial and high temporal resolution applications.
Xenia Mission: Spacecraft Design Concept
NASA Technical Reports Server (NTRS)
Hopkins, R. C.; Johnson, C. L.; Kouveliotou, C.; Jones, D.; Baysinger, M.; Bedsole, T.; Maples, C. C.; Benfield, P. J.; Turner, M.; Capizzo, P.;
2009-01-01
The proposed Xenia mission will, for the first time, chart the chemical and dynamical state of the majority of baryonic matter in the universe. using high-resolution spectroscopy, Xenia will collect essential information from major traces of the formation and evolution of structures from the early universe to the present time. The mission is based on innovative instrumental and observational approaches: observing with fast reaction gamma-ray bursts (GRBs) with a high spectral resolution. This enables the study of their (star-forming) environment from the dark to the local universe and the use of GRBs as backlight of large-scale cosmological structures, observing and surveying extended sources with high sensitivity using two wide field-of-view x-ray telescopes - one with a high angular resolution and the other with a high spectral resolution.
Nishizawa, N; Chen, Y; Hsiung, P; Ippen, E P; Fujimoto, J G
2004-12-15
Real-time, ultrahigh-resolution optical coherence tomography (OCT) is demonstrated in the 1.4-1.7-microm wavelength region with a stretched-pulse, passively mode-locked, Er-doped fiber laser and highly nonlinear fiber. The fiber laser generates 100-mW, linearly chirped pulses at a 51-MHz repetition rate. The pulses are compressed and then coupled into a normally dispersive highly nonlinear fiber to generate a low-noise supercontinuum with a 180-nm FWHM bandwidth and 38 mW of output power. This light source is stable, compact, and broadband, permitting high-speed, real-time, high-resolution OCT imaging. In vivo high-speed OCT imaging of human skin with approximately 5.5-microm resolution and 99-dB sensitivity is demonstrated.
High-resolution absorption measurements of NH3 at high temperatures: 500-2100 cm-1
NASA Astrophysics Data System (ADS)
Barton, Emma J.; Yurchenko, Sergei N.; Tennyson, Jonathan; Clausen, Sønnik; Fateev, Alexander
2015-12-01
High-resolution absorption spectra of NH3 in the region 500-2100 cm-1 at temperatures up to 1027 °C and approximately atmospheric pressure (1013±20 mbar) are measured. NH3 concentrations of 1000 ppm, 0.5% and 1% in volume fraction were used in the measurements. Spectra are recorded in high temperature gas flow cells using a Fourier Transform Infrared (FTIR) spectrometer at a nominal resolution of 0.09 cm-1. Measurements at 22.7 °C are compared to high-resolution cross sections available from the Pacific Northwest National Laboratory (PNNL). The higher temperature spectra are analysed by comparison to a variational line list, BYTe, and experimental energy levels determined using the MARVEL procedure. Approximately 2000 lines have been assigned, of which 851 are newly assigned to mainly hot bands involving vibrational states as high as v2=5.
High-Resolution X-Ray Telescopes
NASA Technical Reports Server (NTRS)
ODell, Stephen L.; Brissenden, Roger J.; Davis, William; Elsner, Ronald F.; Elvis, Martin; Freeman, Mark; Gaetz, Terry; Gorenstein, Paul; Gubarev, Mikhail V.
2010-01-01
Fundamental needs for future x-ray telescopes: a) Sharp images => excellent angular resolution. b) High throughput => large aperture areas. Generation-X optics technical challenges: a) High resolution => precision mirrors & alignment. b) Large apertures => lots of lightweight mirrors. Innovation needed for technical readiness: a) 4 top-level error terms contribute to image size. b) There are approaches to controlling those errors. Innovation needed for manufacturing readiness. Programmatic issues are comparably challenging.
Using High Spatial Resolution Digital Imagery
2005-02-01
digital base maps were high resolution U.S. Geological Survey (USGS) Digital Orthophoto Quarter Quadrangles (DOQQ). The Root Mean Square Errors (RMSE...next step was to assign real world coordinates to the linear im- age. The mosaics were geometrically registered to the panchromatic orthophotos ...useable thematic map from high-resolution imagery. A more practical approach may be to divide the Refuge into a set of smaller areas, or tiles
High Resolution Near Real Time Image Processing and Support for MSSS Modernization
2012-09-01
00-00-2012 to 00-00-2012 4 . TITLE AND SUBTITLE High Resolution Near Real Time Image Processing and Support for MSSS Modernization 5a. CONTRACT...This current CONOPS is depicted in Fig. 4 . Fig. 4 . PCID/ASPIRE High Resolution Post...experiments were performed, and subsequently addressed in papers and presentations [3, 4 ,] that demonstrated system behavior; with details of the
High Spatiotemporal Resolution Prostate MRI
2016-09-01
1 AD AWARD NUMBER: W81XWH-15-1-0341 TITLE: High Spatiotemporal Resolution Prostate MRI PRINCIPAL INVESTIGATOR: Stephen J. Riederer CONTRACTING...REPORT TYPE Annual 3. DATES COVERED 15 Aug 2015 - 14 Aug 2016 4. TITLE AND SUBTITLE High Spatiotemporal Resolution Prostate MRI 5a. CONTRACT NUMBER...improved means using MRI for detecting prostate cancer with the potential for differentiating disease aggressiveness. The hypothesis is that dynamic
Mesosacle eddies in a high resolution OGCM and coupled ocean-atmosphere GCM
NASA Astrophysics Data System (ADS)
Yu, Y.; Liu, H.; Lin, P.
2017-12-01
The present study described high-resolution climate modeling efforts including oceanic, atmospheric and coupled general circulation model (GCM) at the state key laboratory of numerical modeling for atmospheric sciences and geophysical fluid dynamics (LASG), Institute of Atmospheric Physics (IAP). The high-resolution OGCM is established based on the latest version of the LASG/IAP Climate system Ocean Model (LICOM2.1), but its horizontal resolution and vertical resolution are increased to 1/10° and 55 layers, respectively. Forced by the surface fluxes from the reanalysis and observed data, the model has been integrated for approximately more than 80 model years. Compared with the simulation of the coarse-resolution OGCM, the eddy-resolving OGCM not only better simulates the spatial-temporal features of mesoscale eddies and the paths and positions of western boundary currents but also reproduces the large meander of the Kuroshio Current and its interannual variability. Another aspect, namely, the complex structures of equatorial Pacific currents and currents in the coastal ocean of China, are better captured due to the increased horizontal and vertical resolution. Then we coupled the high resolution OGCM to NCAR CAM4 with 25km resolution, in which the mesoscale air-sea interaction processes are better captured.
Generalized Nonlinear Chirp Scaling Algorithm for High-Resolution Highly Squint SAR Imaging.
Yi, Tianzhu; He, Zhihua; He, Feng; Dong, Zhen; Wu, Manqing
2017-11-07
This paper presents a modified approach for high-resolution, highly squint synthetic aperture radar (SAR) data processing. Several nonlinear chirp scaling (NLCS) algorithms have been proposed to solve the azimuth variance of the frequency modulation rates that are caused by the linear range walk correction (LRWC). However, the azimuth depth of focusing (ADOF) is not handled well by these algorithms. The generalized nonlinear chirp scaling (GNLCS) algorithm that is proposed in this paper uses the method of series reverse (MSR) to improve the ADOF and focusing precision. It also introduces a high order processing kernel to avoid the range block processing. Simulation results show that the GNLCS algorithm can enlarge the ADOF and focusing precision for high-resolution highly squint SAR data.
High-resolution DEM Effects on Geophysical Flow Models
NASA Astrophysics Data System (ADS)
Williams, M. R.; Bursik, M. I.; Stefanescu, R. E. R.; Patra, A. K.
2014-12-01
Geophysical mass flow models are numerical models that approximate pyroclastic flow events and can be used to assess the volcanic hazards certain areas may face. One such model, TITAN2D, approximates granular-flow physics based on a depth-averaged analytical model using inputs of basal and internal friction, material volume at a coordinate point, and a GIS in the form of a digital elevation model (DEM). The volume of modeled material propagates over the DEM in a way that is governed by the slope and curvature of the DEM surface and the basal and internal friction angles. Results from TITAN2D are highly dependent upon the inputs to the model. Here we focus on a single input: the DEM, which can vary in resolution. High resolution DEMs are advantageous in that they contain more surface details than lower-resolution models, presumably allowing modeled flows to propagate in a way more true to the real surface. However, very high resolution DEMs can create undesirable artifacts in the slope and curvature that corrupt flow calculations. With high-resolution DEMs becoming more widely available and preferable for use, determining the point at which high resolution data is less advantageous compared to lower resolution data becomes important. We find that in cases of high resolution, integer-valued DEMs, very high-resolution is detrimental to good model outputs when moderate-to-low (<10-15°) slope angles are involved. At these slope angles, multiple adjacent DEM cell elevation values are equal due to the need for the DEM to approximate the low slope with a limited set of integer values for elevation. The first derivative of the elevation surface thus becomes zero. In these cases, flow propagation is inhibited by these spurious zero-slope conditions. Here we present evidence for this "terracing effect" from 1) a mathematically defined simulated elevation model, to demonstrate the terracing effects of integer valued data, and 2) a real-world DEM where terracing must be addressed. We discuss the effect on the flow model output and present possible solutions for rectification of the problem.
Using High Spatial Resolution to Improve BOLD fMRI Detection at 3T
Claise, Béatrice; Jean, Betty
2015-01-01
For different functional magnetic resonance imaging experiments using blood oxygenation level-dependent (BOLD) contrast, the acquisition of T 2*-weighted scans at a high spatial resolution may be advantageous in terms of time-course signal-to-noise ratio and of BOLD sensitivity when the regions are prone to susceptibility artifacts. In this study, we explore this solution by examining how spatial resolution influences activations elicited when appetizing food pictures are viewed. Twenty subjects were imaged at 3 T with two different voxel volumes, 3.4 μl and 27 μl. Despite the diminution of brain coverage, we found that high-resolution acquisition led to a better detection of activations. Though known to suffer to different degrees from susceptibility artifacts, the activations detected by high spatial resolution were notably consistent with those reported in published activation likelihood estimation meta-analyses, corresponding to taste-responsive regions. Furthermore, these regions were found activated bilaterally, in contrast with previous findings. Both the reduction of partial volume effect, which improves BOLD contrast, and the mitigation of susceptibility artifact, which boosts the signal to noise ratio in certain regions, explained the better detection noted with high resolution. The present study provides further evidences that high spatial resolution is a valuable solution for human BOLD fMRI, especially for studying food-related stimuli. PMID:26550990
Near-real-time mosaics from high-resolution side-scan sonar
Danforth, William W.; O'Brien, Thomas F.; Schwab, W.C.
1991-01-01
High-resolution side-scan sonar has proven to be a very effective tool for stuyding and understanding the surficial geology of the seafloor. Since the mid-1970s, the US Geological Survey has used high-resolution side-scan sonar systems for mapping various areas of the continental shelf. However, two problems typically encountered included the short range and the high sampling rate of high-resolution side-scan sonar systems and the acquisition and real-time processing of the enormous volume of sonar data generated by high-resolution suystems. These problems were addressed and overcome in August 1989 when the USGS conducted a side-scan sonar and bottom sampling survey of a 1000-sq-km section of the continental shelf in the Gulf of Farallones located offshore of San Francisco. The primary goal of this survey was to map an area of critical interest for studying continental shelf sediment dynamics. This survey provided an opportunity to test an image processing scheme that enabled production of a side-scan sonar hard-copy mosaic during the cruise in near real-time.
NASA Astrophysics Data System (ADS)
Zhou, Tingting; Gu, Lingjia; Ren, Ruizhi; Cao, Qiong
2016-09-01
With the rapid development of remote sensing technology, the spatial resolution and temporal resolution of satellite imagery also have a huge increase. Meanwhile, High-spatial-resolution images are becoming increasingly popular for commercial applications. The remote sensing image technology has broad application prospects in intelligent traffic. Compared with traditional traffic information collection methods, vehicle information extraction using high-resolution remote sensing image has the advantages of high resolution and wide coverage. This has great guiding significance to urban planning, transportation management, travel route choice and so on. Firstly, this paper preprocessed the acquired high-resolution multi-spectral and panchromatic remote sensing images. After that, on the one hand, in order to get the optimal thresholding for image segmentation, histogram equalization and linear enhancement technologies were applied into the preprocessing results. On the other hand, considering distribution characteristics of road, the normalized difference vegetation index (NDVI) and normalized difference water index (NDWI) were used to suppress water and vegetation information of preprocessing results. Then, the above two processing result were combined. Finally, the geometric characteristics were used to completed road information extraction. The road vector extracted was used to limit the target vehicle area. Target vehicle extraction was divided into bright vehicles extraction and dark vehicles extraction. Eventually, the extraction results of the two kinds of vehicles were combined to get the final results. The experiment results demonstrated that the proposed algorithm has a high precision for the vehicle information extraction for different high resolution remote sensing images. Among these results, the average fault detection rate was about 5.36%, the average residual rate was about 13.60% and the average accuracy was approximately 91.26%.
Single Photon Counting Large Format Imaging Sensors with High Spatial and Temporal Resolution
NASA Astrophysics Data System (ADS)
Siegmund, O. H. W.; Ertley, C.; Vallerga, J. V.; Cremer, T.; Craven, C. A.; Lyashenko, A.; Minot, M. J.
High time resolution astronomical and remote sensing applications have been addressed with microchannel plate based imaging, photon time tagging detector sealed tube schemes. These are being realized with the advent of cross strip readout techniques with high performance encoding electronics and atomic layer deposited (ALD) microchannel plate technologies. Sealed tube devices up to 20 cm square have now been successfully implemented with sub nanosecond timing and imaging. The objective is to provide sensors with large areas (25 cm2 to 400 cm2) with spatial resolutions of <20 μm FWHM and timing resolutions of <100 ps for dynamic imaging. New high efficiency photocathodes for the visible regime are discussed, which also allow response down below 150nm for UV sensing. Borosilicate MCPs are providing high performance, and when processed with ALD techniques are providing order of magnitude lifetime improvements and enhanced photocathode stability. New developments include UV/visible photocathodes, ALD MCPs, and high resolution cross strip anodes for 100 mm detectors. Tests with 50 mm format cross strip readouts suitable for Planacon devices show spatial resolutions better than 20 μm FWHM, with good image linearity while using low gain ( 106). Current cross strip encoding electronics can accommodate event rates of >5 MHz and event timing accuracy of 100 ps. High-performance ASIC versions of these electronics are in development with better event rate, power and mass suitable for spaceflight instruments.
Development of a high resolution optical-fiber tilt sensor by F-P filter
NASA Astrophysics Data System (ADS)
Pan, Jianjun; Nan, Qiuming; Li, Shujie; Hao, Zhonghua
2017-04-01
A high-resolution tilt sensor is developed, which is composed of a pair of optical fiber collimators and a simple pendulum with an F-P filter. The tilt angle is measured by demodulating the shift of center wavelength of F-P filter, which is caused by incidence angle changing. The relationship between tilted angle and the center wavelength is deduced. Calibration experiment results also confirm the deduction, and show that it is easy to obtain a high resolution. Setting the initial angle to 6degree, the measurement range is ±3degree, its average sensitivity is 1104pm/degree, and its average resolution is as high as 0.0009degree.
High Spatial Resolution Thermal Satellite Technologies
NASA Technical Reports Server (NTRS)
Ryan, Robert
2003-01-01
This document in the form of viewslides, reviews various low-cost alternatives to high spatial resolution thermal satellite technologies. There exists no follow-on to Landsat 7 or ASTER high spatial resolution thermal systems. This document reviews the results of the investigation in to the use of new technologies to create a low-cost useful alternative. Three suggested technologies are examined. 1. Conventional microbolometer pushbroom modes offers potential for low cost Landsat Data Continuity Mission (LDCM) thermal or ASTER capability with at least 60-120 ground sampling distance (GSD). 2. Backscanning could produce MultiSpectral Thermal Imager performance without cooled detectors. 3. Cooled detector could produce hyperspectral thermal class system or extremely high spatial resolution class instrument.
Fabrication of [001]-oriented tungsten tips for high resolution scanning tunneling microscopy
Chaika, A. N.; Orlova, N. N.; Semenov, V. N.; Postnova, E. Yu.; Krasnikov, S. A.; Lazarev, M. G.; Chekmazov, S. V.; Aristov, V. Yu.; Glebovsky, V. G.; Bozhko, S. I.; Shvets, I. V.
2014-01-01
The structure of the [001]-oriented single crystalline tungsten probes sharpened in ultra-high vacuum using electron beam heating and ion sputtering has been studied using scanning and transmission electron microscopy. The electron microscopy data prove reproducible fabrication of the single-apex tips with nanoscale pyramids grained by the {011} planes at the apexes. These sharp, [001]-oriented tungsten tips have been successfully utilized in high resolution scanning tunneling microscopy imaging of HOPG(0001), SiC(001) and graphene/SiC(001) surfaces. The electron microscopy characterization performed before and after the high resolution STM experiments provides direct correlation between the tip structure and picoscale spatial resolution achieved in the experiments. PMID:24434734
NASA Astrophysics Data System (ADS)
Yu, Karen; Jacob, Daniel J.; Fisher, Jenny A.; Kim, Patrick S.; Marais, Eloise A.; Miller, Christopher C.; Travis, Katherine R.; Zhu, Lei; Yantosca, Robert M.; Sulprizio, Melissa P.; Cohen, Ron C.; Dibb, Jack E.; Fried, Alan; Mikoviny, Tomas; Ryerson, Thomas B.; Wennberg, Paul O.; Wisthaler, Armin
2016-04-01
Formation of ozone and organic aerosol in continental atmospheres depends on whether isoprene emitted by vegetation is oxidized by the high-NOx pathway (where peroxy radicals react with NO) or by low-NOx pathways (where peroxy radicals react by alternate channels, mostly with HO2). We used mixed layer observations from the SEAC4RS aircraft campaign over the Southeast US to test the ability of the GEOS-Chem chemical transport model at different grid resolutions (0.25° × 0.3125°, 2° × 2.5°, 4° × 5°) to simulate this chemistry under high-isoprene, variable-NOx conditions. Observations of isoprene and NOx over the Southeast US show a negative correlation, reflecting the spatial segregation of emissions; this negative correlation is captured in the model at 0.25° × 0.3125° resolution but not at coarser resolutions. As a result, less isoprene oxidation takes place by the high-NOx pathway in the model at 0.25° × 0.3125° resolution (54 %) than at coarser resolution (59 %). The cumulative probability distribution functions (CDFs) of NOx, isoprene, and ozone concentrations show little difference across model resolutions and good agreement with observations, while formaldehyde is overestimated at coarse resolution because excessive isoprene oxidation takes place by the high-NOx pathway with high formaldehyde yield. The good agreement of simulated and observed concentration variances implies that smaller-scale non-linearities (urban and power plant plumes) are not important on the regional scale. Correlations of simulated vs. observed concentrations do not improve with grid resolution because finer modes of variability are intrinsically more difficult to capture. Higher model resolution leads to decreased conversion of NOx to organic nitrates and increased conversion to nitric acid, with total reactive nitrogen oxides (NOy) changing little across model resolutions. Model concentrations in the lower free troposphere are also insensitive to grid resolution. The overall low sensitivity of modeled concentrations to grid resolution implies that coarse resolution is adequate when modeling continental boundary layer chemistry for global applications.
A 4.5 km resolution Arctic Ocean simulation with the global multi-resolution model FESOM 1.4
NASA Astrophysics Data System (ADS)
Wang, Qiang; Wekerle, Claudia; Danilov, Sergey; Wang, Xuezhu; Jung, Thomas
2018-04-01
In the framework of developing a global modeling system which can facilitate modeling studies on Arctic Ocean and high- to midlatitude linkage, we evaluate the Arctic Ocean simulated by the multi-resolution Finite Element Sea ice-Ocean Model (FESOM). To explore the value of using high horizontal resolution for Arctic Ocean modeling, we use two global meshes differing in the horizontal resolution only in the Arctic Ocean (24 km vs. 4.5 km). The high resolution significantly improves the model's representation of the Arctic Ocean. The most pronounced improvement is in the Arctic intermediate layer, in terms of both Atlantic Water (AW) mean state and variability. The deepening and thickening bias of the AW layer, a common issue found in coarse-resolution simulations, is significantly alleviated by using higher resolution. The topographic steering of the AW is stronger and the seasonal and interannual temperature variability along the ocean bottom topography is enhanced in the high-resolution simulation. The high resolution also improves the ocean surface circulation, mainly through a better representation of the narrow straits in the Canadian Arctic Archipelago (CAA). The representation of CAA throughflow not only influences the release of water masses through the other gateways but also the circulation pathways inside the Arctic Ocean. However, the mean state and variability of Arctic freshwater content and the variability of freshwater transport through the Arctic gateways appear not to be very sensitive to the increase in resolution employed here. By highlighting the issues that are independent of model resolution, we address that other efforts including the improvement of parameterizations are still required.
FDR-controlled metabolite annotation for high-resolution imaging mass spectrometry.
Palmer, Andrew; Phapale, Prasad; Chernyavsky, Ilya; Lavigne, Regis; Fay, Dominik; Tarasov, Artem; Kovalev, Vitaly; Fuchser, Jens; Nikolenko, Sergey; Pineau, Charles; Becker, Michael; Alexandrov, Theodore
2017-01-01
High-mass-resolution imaging mass spectrometry promises to localize hundreds of metabolites in tissues, cell cultures, and agar plates with cellular resolution, but it is hampered by the lack of bioinformatics tools for automated metabolite identification. We report pySM, a framework for false discovery rate (FDR)-controlled metabolite annotation at the level of the molecular sum formula, for high-mass-resolution imaging mass spectrometry (https://github.com/alexandrovteam/pySM). We introduce a metabolite-signal match score and a target-decoy FDR estimate for spatial metabolomics.
NASA Astrophysics Data System (ADS)
Nocente, M.; Tardocchi, M.; Olariu, A.; Olariu, S.; Pereira, R. C.; Chugunov, I. N.; Fernandes, A.; Gin, D. B.; Grosso, G.; Kiptily, V. G.; Neto, A.; Shevelev, A. E.; Silva, M.; Sousa, J.; Gorini, G.
2013-04-01
High resolution γ-ray spectroscopy measurements at MHz counting rates were carried out at nuclear accelerators, combining a LaBr 3(Ce) detector with dedicated hardware and software solutions based on digitization and off-line analysis. Spectra were measured at counting rates up to 4 MHz, with little or no degradation of the energy resolution, adopting a pile up rejection algorithm. The reported results represent a step forward towards the final goal of high resolution γ-ray spectroscopy measurements on a burning plasma device.
Umehara, Kensuke; Ota, Junko; Ishida, Takayuki
2017-10-18
In this study, the super-resolution convolutional neural network (SRCNN) scheme, which is the emerging deep-learning-based super-resolution method for enhancing image resolution in chest CT images, was applied and evaluated using the post-processing approach. For evaluation, 89 chest CT cases were sampled from The Cancer Imaging Archive. The 89 CT cases were divided randomly into 45 training cases and 44 external test cases. The SRCNN was trained using the training dataset. With the trained SRCNN, a high-resolution image was reconstructed from a low-resolution image, which was down-sampled from an original test image. For quantitative evaluation, two image quality metrics were measured and compared to those of the conventional linear interpolation methods. The image restoration quality of the SRCNN scheme was significantly higher than that of the linear interpolation methods (p < 0.001 or p < 0.05). The high-resolution image reconstructed by the SRCNN scheme was highly restored and comparable to the original reference image, in particular, for a ×2 magnification. These results indicate that the SRCNN scheme significantly outperforms the linear interpolation methods for enhancing image resolution in chest CT images. The results also suggest that SRCNN may become a potential solution for generating high-resolution CT images from standard CT images.
High-Resolution Land Use and Land Cover Mapping
,
1999-01-01
As the Nation?s population grows, quantifying, monitoring, and managing land use becomes increasingly important. The U.S. Geological Survey (USGS) has a long heritage of leadership and innovation in land use and land cover (LULC) mapping that has been the model both nationally and internationally for over 20 years. At present, the USGS is producing high-resolution LULC data for several watershed and urban areas within the United States. This high-resolution LULC mapping is part of an ongoing USGS Land Cover Characterization Program (LCCP). The four components of the LCCP are global (1:2,000,000-scale), national (1:100,000-scale), urban (1:24,000-scale), and special projects (various scales and time periods). Within the urban and special project components, the USGS Rocky Mountain Mapping Center (RMMC) is collecting historical as well as contemporary high-resolution LULC data. RMMC?s high-resolution LULC mapping builds on the heritage and success of previous USGS LULC programs and provides LULC information to meet user requirements.
MPGD for breast cancer prevention: a high resolution and low dose radiation medical imaging
NASA Astrophysics Data System (ADS)
Gutierrez, R. M.; Cerquera, E. A.; Mañana, G.
2012-07-01
Early detection of small calcifications in mammograms is considered the best preventive tool of breast cancer. However, existing digital mammography with relatively low radiation skin exposure has limited accessibility and insufficient spatial resolution for small calcification detection. Micro Pattern Gaseous Detectors (MPGD) and associated technologies, increasingly provide new information useful to generate images of microscopic structures and make more accessible cutting edge technology for medical imaging and many other applications. In this work we foresee and develop an application for the new information provided by a MPGD camera in the form of highly controlled images with high dynamical resolution. We present a new Super Detail Image (S-DI) that efficiently profits of this new information provided by the MPGD camera to obtain very high spatial resolution images. Therefore, the method presented in this work shows that the MPGD camera with SD-I, can produce mammograms with the necessary spatial resolution to detect microcalcifications. It would substantially increase efficiency and accessibility of screening mammography to highly improve breast cancer prevention.
NASA Astrophysics Data System (ADS)
Widmann, K.; Beiersdorfer, P.; Magee, E. W.; Boyle, D. P.; Kaita, R.; Majeski, R.
2014-11-01
We have constructed a high-resolution grazing-incidence spectrometer designed for measuring the ion temperature of low-Z elements, such as Li+ or Li2 +, which radiate near 199 Å and 135 Å, respectively. Based on measurements at the Livermore Electron Beam Ion Trap we have shown that the instrumental resolution is better than 48 mÅ at the 200 Å setting and better than 40 mÅ for the 135-Å range. Such a high spectral resolution corresponds to an instrumental limit for line-width based temperature measurements of about 45 eV for the 199 Å Li+ and 65 eV for the 135 Å Li2 + lines. Recently obtained survey spectra from the Lithium Tokamak Experiment at the Princeton Plasma Physics Laboratory show the presence of these lithium emission lines and the expected core ion temperature of approximately 70 eV is sufficiently high to demonstrate the feasibility of utilizing our high-resolution spectrometer as an ion-temperature diagnostic.
Feng, Wei; Zhang, Fumin; Qu, Xinghua; Zheng, Shiwei
2016-01-01
High-speed photography is an important tool for studying rapid physical phenomena. However, low-frame-rate CCD (charge coupled device) or CMOS (complementary metal oxide semiconductor) camera cannot effectively capture the rapid phenomena with high-speed and high-resolution. In this paper, we incorporate the hardware restrictions of existing image sensors, design the sampling functions, and implement a hardware prototype with a digital micromirror device (DMD) camera in which spatial and temporal information can be flexibly modulated. Combined with the optical model of DMD camera, we theoretically analyze the per-pixel coded exposure and propose a three-element median quicksort method to increase the temporal resolution of the imaging system. Theoretically, this approach can rapidly increase the temporal resolution several, or even hundreds, of times without increasing bandwidth requirements of the camera. We demonstrate the effectiveness of our method via extensive examples and achieve 100 fps (frames per second) gain in temporal resolution by using a 25 fps camera. PMID:26959023
Feng, Wei; Zhang, Fumin; Qu, Xinghua; Zheng, Shiwei
2016-03-04
High-speed photography is an important tool for studying rapid physical phenomena. However, low-frame-rate CCD (charge coupled device) or CMOS (complementary metal oxide semiconductor) camera cannot effectively capture the rapid phenomena with high-speed and high-resolution. In this paper, we incorporate the hardware restrictions of existing image sensors, design the sampling functions, and implement a hardware prototype with a digital micromirror device (DMD) camera in which spatial and temporal information can be flexibly modulated. Combined with the optical model of DMD camera, we theoretically analyze the per-pixel coded exposure and propose a three-element median quicksort method to increase the temporal resolution of the imaging system. Theoretically, this approach can rapidly increase the temporal resolution several, or even hundreds, of times without increasing bandwidth requirements of the camera. We demonstrate the effectiveness of our method via extensive examples and achieve 100 fps (frames per second) gain in temporal resolution by using a 25 fps camera.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Deng, B. H., E-mail: bdeng@trialphaenergy.com; Beall, M.; Schroeder, J.
2016-11-15
A high sensitivity multi-channel far infrared laser diagnostics with switchable interferometry and polarimetry operation modes for the advanced neutral beam-driven C-2U field-reversed configuration (FRC) plasmas is described. The interferometer achieved superior resolution of 1 × 10{sup 16} m{sup −2} at >1.5 MHz bandwidth, illustrated by measurement of small amplitude high frequency fluctuations. The polarimetry achieved 0.04° instrument resolution and 0.1° actual resolution in the challenging high density gradient environment with >0.5 MHz bandwidth, making it suitable for weak internal magnetic field measurements in the C-2U plasmas, where the maximum Faraday rotation angle is less than 1°. The polarimetry resolution datamore » is analyzed, and high resolution Faraday rotation data in C-2U is presented together with direct evidences of field reversal in FRC magnetic structure obtained for the first time by a non-perturbative method.« less
Gerbich, Therese M.; Rana, Kishan; Suzuki, Aussie; Schaefer, Kristina N.; Heppert, Jennifer K.; Boothby, Thomas C.; Allbritton, Nancy L.; Gladfelter, Amy S.; Maddox, Amy S.
2018-01-01
Fluorescence microscopy is a powerful approach for studying subcellular dynamics at high spatiotemporal resolution; however, conventional fluorescence microscopy techniques are light-intensive and introduce unnecessary photodamage. Light-sheet fluorescence microscopy (LSFM) mitigates these problems by selectively illuminating the focal plane of the detection objective by using orthogonal excitation. Orthogonal excitation requires geometries that physically limit the detection objective numerical aperture (NA), thereby limiting both light-gathering efficiency (brightness) and native spatial resolution. We present a novel live-cell LSFM method, lateral interference tilted excitation (LITE), in which a tilted light sheet illuminates the detection objective focal plane without a sterically limiting illumination scheme. LITE is thus compatible with any detection objective, including oil immersion, without an upper NA limit. LITE combines the low photodamage of LSFM with high resolution, high brightness, and coverslip-based objectives. We demonstrate the utility of LITE for imaging animal, fungal, and plant model organisms over many hours at high spatiotemporal resolution. PMID:29490939
USDA-ARS?s Scientific Manuscript database
Construction of genetic linkage map is essential for genetic and genomic studies. Recent advances in sequencing and genotyping technologies made it possible to generate high-density and high-resolution genetic linkage maps, especially for the organisms lacking extensive genomic resources. In the pre...
AVHRR/1-FM Advanced Very High Resolution Radiometer
NASA Technical Reports Server (NTRS)
1979-01-01
The advanced very high resolution radiometer is discussed. The program covers design, construction, and test of a breadboard model, engineering model, protoflight model, mechanical/structural model, and a life test model. Special bench test and calibration equipment was developed for use on the program. The flight model program objectives were to fabricate, assemble and test four of the advanced very high resolution radiometers along with a bench cooler and collimator.
High resolution studies of the solar X-ray corona from Aerobee rockets
NASA Technical Reports Server (NTRS)
Davis, J. M.; Haggerty, R.; Krieger, A. S.; Manko, H.; Sherman, G.; Ting, J. W. S.; Vaiana, G. S.
1973-01-01
The research in high resolution solar X-ray astronomy is reported. The payload for the Aerobee 150 launch vehicle, which included a 23 cm diameter mirror whose polished surface was a nickel-phosphorus alloy is discussed along with the high resolution measurements, by Flight 13.028 CS, of the temperature and density structure of the lower corona. Flight 13.029 CS is also discussed.
2010-07-01
W81XWH-09-1-0420 TITLE: High Resolution PET Imaging Probe for the Detection, Molecular Characterization and Treatment Monitoring of Prostate Cancer...4. TITLE AND SUBTITLE High-Resolution PET Imaging Probe for the Detection, Molecular Characterization and Treatment of Prostate Cancer... molecular imaging for diagnosis as well as treatment planning and monitoring in prostate cancer. This investigation hypothesizes that a dedicated
2010-10-14
High-Resolution Functional Mapping of the Venezuelan Equine Encephalitis Virus Genome by Insertional Mutagenesis and Massively Parallel Sequencing...Venezuelan equine encephalitis virus (VEEV) genome. We initially used a capillary electrophoresis method to gain insight into the role of the VEEV...Smith JM, Schmaljohn CS (2010) High-Resolution Functional Mapping of the Venezuelan Equine Encephalitis Virus Genome by Insertional Mutagenesis and
NASA Technical Reports Server (NTRS)
Pagnutti, Mary
2006-01-01
This viewgraph presentation reviews the creation of a prototype algorithm for atmospheric correction using high spatial resolution earth observing imaging systems. The objective of the work was to evaluate accuracy of a prototype algorithm that uses satellite-derived atmospheric products to generate scene reflectance maps for high spatial resolution (HSR) systems. This presentation focused on preliminary results of only the satellite-based atmospheric correction algorithm.
Zhu, Hongchun; Cai, Lijie; Liu, Haiying; Huang, Wei
2016-01-01
Multi-scale image segmentation and the selection of optimal segmentation parameters are the key processes in the object-oriented information extraction of high-resolution remote sensing images. The accuracy of remote sensing special subject information depends on this extraction. On the basis of WorldView-2 high-resolution data, the optimal segmentation parameters methodof object-oriented image segmentation and high-resolution image information extraction, the following processes were conducted in this study. Firstly, the best combination of the bands and weights was determined for the information extraction of high-resolution remote sensing image. An improved weighted mean-variance method was proposed andused to calculatethe optimal segmentation scale. Thereafter, the best shape factor parameter and compact factor parameters were computed with the use of the control variables and the combination of the heterogeneity and homogeneity indexes. Different types of image segmentation parameters were obtained according to the surface features. The high-resolution remote sensing images were multi-scale segmented with the optimal segmentation parameters. Ahierarchical network structure was established by setting the information extraction rules to achieve object-oriented information extraction. This study presents an effective and practical method that can explain expert input judgment by reproducible quantitative measurements. Furthermore the results of this procedure may be incorporated into a classification scheme. PMID:27362762
Zhu, Hongchun; Cai, Lijie; Liu, Haiying; Huang, Wei
2016-01-01
Multi-scale image segmentation and the selection of optimal segmentation parameters are the key processes in the object-oriented information extraction of high-resolution remote sensing images. The accuracy of remote sensing special subject information depends on this extraction. On the basis of WorldView-2 high-resolution data, the optimal segmentation parameters methodof object-oriented image segmentation and high-resolution image information extraction, the following processes were conducted in this study. Firstly, the best combination of the bands and weights was determined for the information extraction of high-resolution remote sensing image. An improved weighted mean-variance method was proposed andused to calculatethe optimal segmentation scale. Thereafter, the best shape factor parameter and compact factor parameters were computed with the use of the control variables and the combination of the heterogeneity and homogeneity indexes. Different types of image segmentation parameters were obtained according to the surface features. The high-resolution remote sensing images were multi-scale segmented with the optimal segmentation parameters. Ahierarchical network structure was established by setting the information extraction rules to achieve object-oriented information extraction. This study presents an effective and practical method that can explain expert input judgment by reproducible quantitative measurements. Furthermore the results of this procedure may be incorporated into a classification scheme.
Evacuee Compliance Behavior Analysis using High Resolution Demographic Information
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lu, Wei; Han, Lee; Liu, Cheng
2014-01-01
The purpose of this study is to examine whether evacuee compliance behavior with route assignments from different resolutions of demographic data would impact the evacuation performance. Most existing evacuation strategies assume that travelers will follow evacuation instructions, while in reality a certain percent of evacuees do not comply with prescribed instructions. In this paper, a comparison study of evacuation assignment based on Traffic Analysis Zones (TAZ) and high resolution LandScan USA Population Cells (LPC) were conducted for the detailed road network representing Alexandria, Virginia. A revised platform for evacuation modeling built on high resolution demographic data and activity-based microscopic trafficmore » simulation is proposed. The results indicate that evacuee compliance behavior affects evacuation efficiency with traditional TAZ assignment, but it does not significantly compromise the efficiency with high resolution LPC assignment. The TAZ assignment also underestimates the real travel time during evacuation, especially for high compliance simulations. This suggests that conventional evacuation studies based on TAZ assignment might not be effective at providing efficient guidance to evacuees. From the high resolution data perspective, traveler compliance behavior is an important factor but it does not impact the system performance significantly. The highlight of evacuee compliance behavior analysis should be emphasized on individual evacuee level route/shelter assignments, rather than the whole system performance.« less
Dorji, Passang; Fearns, Peter
2017-01-01
The impact of anthropogenic activities on coastal waters is a cause of concern because such activities add to the total suspended sediment (TSS) budget of the coastal waters, which have negative impacts on the coastal ecosystem. Satellite remote sensing provides a powerful tool in monitoring TSS concentration at high spatiotemporal resolution, but coastal managers should be mindful that the satellite-derived TSS concentrations are dependent on the satellite sensor's radiometric properties, atmospheric correction approaches, the spatial resolution and the limitations of specific TSS algorithms. In this study, we investigated the impact of different spatial resolutions of satellite sensor on the quantification of TSS concentration in coastal waters of northern Western Australia. We quantified the TSS product derived from MODerate resolution Imaging Spectroradiometer (MODIS)-Aqua, Landsat-8 Operational Land Image (OLI), and WorldView-2 (WV2) at native spatial resolutions of 250 m, 30 m and 2 m respectively and coarser spatial resolution (resampled up to 5 km) to quantify the impact of spatial resolution on the derived TSS product in different turbidity conditions. The results from the study show that in the waters of high turbidity and high spatial variability, the high spatial resolution WV2 sensor reported TSS concentration as high as 160 mg L-1 while the low spatial resolution MODIS-Aqua reported a maximum TSS concentration of 23.6 mg L-1. Degrading the spatial resolution of each satellite sensor for highly spatially variable turbid waters led to variability in the TSS concentrations of 114.46%, 304.68% and 38.2% for WV2, Landsat-8 OLI and MODIS-Aqua respectively. The implications of this work are particularly relevant in the situation of compliance monitoring where operations may be required to restrict TSS concentrations to a pre-defined limit.
Fearns, Peter
2017-01-01
The impact of anthropogenic activities on coastal waters is a cause of concern because such activities add to the total suspended sediment (TSS) budget of the coastal waters, which have negative impacts on the coastal ecosystem. Satellite remote sensing provides a powerful tool in monitoring TSS concentration at high spatiotemporal resolution, but coastal managers should be mindful that the satellite-derived TSS concentrations are dependent on the satellite sensor’s radiometric properties, atmospheric correction approaches, the spatial resolution and the limitations of specific TSS algorithms. In this study, we investigated the impact of different spatial resolutions of satellite sensor on the quantification of TSS concentration in coastal waters of northern Western Australia. We quantified the TSS product derived from MODerate resolution Imaging Spectroradiometer (MODIS)-Aqua, Landsat-8 Operational Land Image (OLI), and WorldView-2 (WV2) at native spatial resolutions of 250 m, 30 m and 2 m respectively and coarser spatial resolution (resampled up to 5 km) to quantify the impact of spatial resolution on the derived TSS product in different turbidity conditions. The results from the study show that in the waters of high turbidity and high spatial variability, the high spatial resolution WV2 sensor reported TSS concentration as high as 160 mg L-1 while the low spatial resolution MODIS-Aqua reported a maximum TSS concentration of 23.6 mg L-1. Degrading the spatial resolution of each satellite sensor for highly spatially variable turbid waters led to variability in the TSS concentrations of 114.46%, 304.68% and 38.2% for WV2, Landsat-8 OLI and MODIS-Aqua respectively. The implications of this work are particularly relevant in the situation of compliance monitoring where operations may be required to restrict TSS concentrations to a pre-defined limit. PMID:28380059
Evaluation of coarse scale land surface remote sensing albedo product over rugged terrain
NASA Astrophysics Data System (ADS)
Wen, J.; Xinwen, L.; You, D.; Dou, B.
2017-12-01
Satellite derived Land surface albedo is an essential climate variable which controls the earth energy budget and it can be used in applications such as climate change, hydrology, and numerical weather prediction. The accuracy and uncertainty of surface albedo products should be evaluated with a reliable reference truth data prior to applications. And more literatures investigated the validation methods about the albedo validation in a flat or homogenous surface. However, the albedo performance over rugged terrain is still unknow due to the validation method limited. A multi-validation strategy is implemented to give a comprehensive albedo validation, which will involve the high resolution albedo processing, high resolution albedo validation based on in situ albedo, and the method to upscale the high resolution albedo to a coarse scale albedo. Among them, the high resolution albedo generation and the upscale method is the core step for the coarse scale albedo validation. In this paper, the high resolution albedo is generated by Angular Bin algorithm. And a albedo upscale method over rugged terrain is developed to obtain the coarse scale albedo truth. The in situ albedo located 40 sites in mountain area are selected globally to validate the high resolution albedo, and then upscaled to the coarse scale albedo by the upscale method. This paper takes MODIS and GLASS albedo product as a example, and the prelimarily results show the RMSE of MODIS and GLASS albedo product over rugged terrain are 0.047 and 0.057, respectively under the RMSE with 0.036 of high resolution albedo.
NASA Astrophysics Data System (ADS)
Husain, S. Z.; Separovic, L.; Yu, W.; Fernig, D.
2014-12-01
Extended-range high-resolution mesoscale simulations with limited-area atmospheric models when applied to downscale regional analysis fields over large spatial domains can provide valuable information for many applications including the weather-dependent renewable energy industry. Long-term simulations over a continental-scale spatial domain, however, require mechanisms to control the large-scale deviations in the high-resolution simulated fields from the coarse-resolution driving fields. As enforcement of the lateral boundary conditions is insufficient to restrict such deviations, large scales in the simulated high-resolution meteorological fields are therefore spectrally nudged toward the driving fields. Different spectral nudging approaches, including the appropriate nudging length scales as well as the vertical profiles and temporal relaxations for nudging, have been investigated to propose an optimal nudging strategy. Impacts of time-varying nudging and generation of hourly analysis estimates are explored to circumvent problems arising from the coarse temporal resolution of the regional analysis fields. Although controlling the evolution of the atmospheric large scales generally improves the outputs of high-resolution mesoscale simulations within the surface layer, the prognostically evolving surface fields can nevertheless deviate from their expected values leading to significant inaccuracies in the predicted surface layer meteorology. A forcing strategy based on grid nudging of the different surface fields, including surface temperature, soil moisture, and snow conditions, toward their expected values obtained from a high-resolution offline surface scheme is therefore proposed to limit any considerable deviation. Finally, wind speed and temperature at wind turbine hub height predicted by different spectrally nudged extended-range simulations are compared against observations to demonstrate possible improvements achievable using higher spatiotemporal resolution.
The fusion of satellite and UAV data: simulation of high spatial resolution band
NASA Astrophysics Data System (ADS)
Jenerowicz, Agnieszka; Siok, Katarzyna; Woroszkiewicz, Malgorzata; Orych, Agata
2017-10-01
Remote sensing techniques used in the precision agriculture and farming that apply imagery data obtained with sensors mounted on UAV platforms became more popular in the last few years due to the availability of low- cost UAV platforms and low- cost sensors. Data obtained from low altitudes with low- cost sensors can be characterised by high spatial and radiometric resolution but quite low spectral resolution, therefore the application of imagery data obtained with such technology is quite limited and can be used only for the basic land cover classification. To enrich the spectral resolution of imagery data acquired with low- cost sensors from low altitudes, the authors proposed the fusion of RGB data obtained with UAV platform with multispectral satellite imagery. The fusion is based on the pansharpening process, that aims to integrate the spatial details of the high-resolution panchromatic image with the spectral information of lower resolution multispectral or hyperspectral imagery to obtain multispectral or hyperspectral images with high spatial resolution. The key of pansharpening is to properly estimate the missing spatial details of multispectral images while preserving their spectral properties. In the research, the authors presented the fusion of RGB images (with high spatial resolution) obtained with sensors mounted on low- cost UAV platforms and multispectral satellite imagery with satellite sensors, i.e. Landsat 8 OLI. To perform the fusion of UAV data with satellite imagery, the simulation of the panchromatic bands from RGB data based on the spectral channels linear combination, was conducted. Next, for simulated bands and multispectral satellite images, the Gram-Schmidt pansharpening method was applied. As a result of the fusion, the authors obtained several multispectral images with very high spatial resolution and then analysed the spatial and spectral accuracies of processed images.
Patch-Based Super-Resolution of MR Spectroscopic Images: Application to Multiple Sclerosis
Jain, Saurabh; Sima, Diana M.; Sanaei Nezhad, Faezeh; Hangel, Gilbert; Bogner, Wolfgang; Williams, Stephen; Van Huffel, Sabine; Maes, Frederik; Smeets, Dirk
2017-01-01
Purpose: Magnetic resonance spectroscopic imaging (MRSI) provides complementary information to conventional magnetic resonance imaging. Acquiring high resolution MRSI is time consuming and requires complex reconstruction techniques. Methods: In this paper, a patch-based super-resolution method is presented to increase the spatial resolution of metabolite maps computed from MRSI. The proposed method uses high resolution anatomical MR images (T1-weighted and Fluid-attenuated inversion recovery) to regularize the super-resolution process. The accuracy of the method is validated against conventional interpolation techniques using a phantom, as well as simulated and in vivo acquired human brain images of multiple sclerosis subjects. Results: The method preserves tissue contrast and structural information, and matches well with the trend of acquired high resolution MRSI. Conclusions: These results suggest that the method has potential for clinically relevant neuroimaging applications. PMID:28197066
Computational high-resolution optical imaging of the living human retina
NASA Astrophysics Data System (ADS)
Shemonski, Nathan D.; South, Fredrick A.; Liu, Yuan-Zhi; Adie, Steven G.; Scott Carney, P.; Boppart, Stephen A.
2015-07-01
High-resolution in vivo imaging is of great importance for the fields of biology and medicine. The introduction of hardware-based adaptive optics (HAO) has pushed the limits of optical imaging, enabling high-resolution near diffraction-limited imaging of previously unresolvable structures. In ophthalmology, when combined with optical coherence tomography, HAO has enabled a detailed three-dimensional visualization of photoreceptor distributions and individual nerve fibre bundles in the living human retina. However, the introduction of HAO hardware and supporting software adds considerable complexity and cost to an imaging system, limiting the number of researchers and medical professionals who could benefit from the technology. Here we demonstrate a fully automated computational approach that enables high-resolution in vivo ophthalmic imaging without the need for HAO. The results demonstrate that computational methods in coherent microscopy are applicable in highly dynamic living systems.
Rapid calibrated high-resolution hyperspectral imaging using tunable laser source
NASA Astrophysics Data System (ADS)
Nguyen, Lam K.; Margalith, Eli
2009-05-01
We present a novel hyperspectral imaging technique based on tunable laser technology. By replacing the broadband source and tunable filters of a typical NIR imaging instrument, several advantages are realized, including: high spectral resolution, highly variable field-of-views, fast scan-rates, high signal-to-noise ratio, and the ability to use optical fiber for efficient and flexible sample illumination. With this technique, high-resolution, calibrated hyperspectral images over the NIR range can be acquired in seconds. The performance of system features will be demonstrated on two example applications: detecting melamine contamination in wheat gluten and separating bovine protein from wheat protein in cattle feed.
Heidemann, Robin M; Anwander, Alfred; Feiweier, Thorsten; Knösche, Thomas R; Turner, Robert
2012-04-02
There is ongoing debate whether using a higher spatial resolution (sampling k-space) or a higher angular resolution (sampling q-space angles) is the better way to improve diffusion MRI (dMRI) based tractography results in living humans. In both cases, the limiting factor is the signal-to-noise ratio (SNR), due to the restricted acquisition time. One possible way to increase the spatial resolution without sacrificing either SNR or angular resolution is to move to a higher magnetic field strength. Nevertheless, dMRI has not been the preferred application for ultra-high field strength (7 T). This is because single-shot echo-planar imaging (EPI) has been the method of choice for human in vivo dMRI. EPI faces several challenges related to the use of a high resolution at high field strength, for example, distortions and image blurring. These problems can easily compromise the expected SNR gain with field strength. In the current study, we introduce an adapted EPI sequence in conjunction with a combination of ZOOmed imaging and Partially Parallel Acquisition (ZOOPPA). We demonstrate that the method can produce high quality diffusion-weighted images with high spatial and angular resolution at 7 T. We provide examples of in vivo human dMRI with isotropic resolutions of 1 mm and 800 μm. These data sets are particularly suitable for resolving complex and subtle fiber architectures, including fiber crossings in the white matter, anisotropy in the cortex and fibers entering the cortex. Copyright © 2011 Elsevier Inc. All rights reserved.
Koen, Joshua D; Borders, Alyssa A; Petzold, Michael T; Yonelinas, Andrew P
2017-02-01
The medial temporal lobe (MTL) plays a critical role in episodic long-term memory, but whether the MTL is necessary for visual short-term memory is controversial. Some studies have indicated that MTL damage disrupts visual short-term memory performance whereas other studies have failed to find such evidence. To account for these mixed results, it has been proposed that the hippocampus is critical in supporting short-term memory for high resolution complex bindings, while the cortex is sufficient to support simple, low resolution bindings. This hypothesis was tested in the current study by assessing visual short-term memory in patients with damage to the MTL and controls for high resolution and low resolution object-location and object-color associations. In the location tests, participants encoded sets of two or four objects in different locations on the screen. After each set, participants performed a two-alternative forced-choice task in which they were required to discriminate the object in the target location from the object in a high or low resolution lure location (i.e., the object locations were very close or far away from the target location, respectively). Similarly, in the color tests, participants were presented with sets of two or four objects in a different color and, after each set, were required to discriminate the object in the target color from the object in a high or low resolution lure color (i.e., the lure color was very similar or very different, respectively, to the studied color). The patients were significantly impaired in visual short-term memory, but importantly, they were more impaired for high resolution object-location and object-color bindings. The results are consistent with the proposal that the hippocampus plays a critical role in forming and maintaining complex, high resolution bindings. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.
Multiple Sensor Camera for Enhanced Video Capturing
NASA Astrophysics Data System (ADS)
Nagahara, Hajime; Kanki, Yoshinori; Iwai, Yoshio; Yachida, Masahiko
A resolution of camera has been drastically improved under a current request for high-quality digital images. For example, digital still camera has several mega pixels. Although a video camera has the higher frame-rate, the resolution of a video camera is lower than that of still camera. Thus, the high-resolution is incompatible with the high frame rate of ordinary cameras in market. It is difficult to solve this problem by a single sensor, since it comes from physical limitation of the pixel transfer rate. In this paper, we propose a multi-sensor camera for capturing a resolution and frame-rate enhanced video. Common multi-CCDs camera, such as 3CCD color camera, has same CCD for capturing different spectral information. Our approach is to use different spatio-temporal resolution sensors in a single camera cabinet for capturing higher resolution and frame-rate information separately. We build a prototype camera which can capture high-resolution (2588×1958 pixels, 3.75 fps) and high frame-rate (500×500, 90 fps) videos. We also proposed the calibration method for the camera. As one of the application of the camera, we demonstrate an enhanced video (2128×1952 pixels, 90 fps) generated from the captured videos for showing the utility of the camera.
Automatic public access to documents and maps stored on and internal secure system.
NASA Astrophysics Data System (ADS)
Trench, James; Carter, Mary
2013-04-01
The Geological Survey of Ireland operates a Document Management System for providing documents and maps stored internally in high resolution and in a high level secure environment, to an external service where the documents are automatically presented in a lower resolution to members of the public. Security is devised through roles and Individual Users where role level and folder level can be set. The application is an electronic document/data management (EDM) system which has a Geographical Information System (GIS) component integrated to allow users to query an interactive map of Ireland for data that relates to a particular area of interest. The data stored in the database consists of Bedrock Field Sheets, Bedrock Notebooks, Bedrock Maps, Geophysical Surveys, Geotechnical Maps & Reports, Groundwater, GSI Publications, Marine, Mine Records, Mineral Localities, Open File, Quaternary and Unpublished Reports. The Konfig application Tool is both an internal and public facing application. It acts as a tool for high resolution data entry which are stored in a high resolution vault. The public facing application is a mirror of the internal application and differs only in that the application furnishes high resolution data into low resolution format which is stored in a low resolution vault thus, making the data web friendly to the end user for download.
Gao, Mingxing; Xu, Xiwei; Klinger, Yann; van der Woerd, Jerome; Tapponnier, Paul
2017-08-15
The recent dramatic increase in millimeter- to centimeter- resolution topographic datasets obtained via multi-view photogrammetry raises the possibility of mapping detailed offset geomorphology and constraining the spatial characteristics of active faults. Here, for the first time, we applied this new method to acquire high-resolution imagery and generate topographic data along the Altyn Tagh fault, which is located in a remote high elevation area and shows preserved ancient earthquake surface ruptures. A digital elevation model (DEM) with a resolution of 0.065 m and an orthophoto with a resolution of 0.016 m were generated from these images. We identified piercing markers and reconstructed offsets based on both the orthoimage and the topography. The high-resolution UAV data were used to accurately measure the recent seismic offset. We obtained the recent offset of 7 ± 1 m. Combined with the high resolution satellite image, we measured cumulative offsets of 15 ± 2 m, 20 ± 2 m, 30 ± 2 m, which may be due to multiple paleo-earthquakes. Therefore, UAV mapping can provide fine-scale data for the assessment of the seismic hazards.
Generalized Nonlinear Chirp Scaling Algorithm for High-Resolution Highly Squint SAR Imaging
He, Zhihua; He, Feng; Dong, Zhen; Wu, Manqing
2017-01-01
This paper presents a modified approach for high-resolution, highly squint synthetic aperture radar (SAR) data processing. Several nonlinear chirp scaling (NLCS) algorithms have been proposed to solve the azimuth variance of the frequency modulation rates that are caused by the linear range walk correction (LRWC). However, the azimuth depth of focusing (ADOF) is not handled well by these algorithms. The generalized nonlinear chirp scaling (GNLCS) algorithm that is proposed in this paper uses the method of series reverse (MSR) to improve the ADOF and focusing precision. It also introduces a high order processing kernel to avoid the range block processing. Simulation results show that the GNLCS algorithm can enlarge the ADOF and focusing precision for high-resolution highly squint SAR data. PMID:29112151
Evaluating the Value of High Spatial Resolution in National Capacity Expansion Models using ReEDS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Krishnan, Venkat; Cole, Wesley
2016-11-14
Power sector capacity expansion models (CEMs) have a broad range of spatial resolutions. This paper uses the Regional Energy Deployment System (ReEDS) model, a long-term national scale electric sector CEM, to evaluate the value of high spatial resolution for CEMs. ReEDS models the United States with 134 load balancing areas (BAs) and captures the variability in existing generation parameters, future technology costs, performance, and resource availability using very high spatial resolution data, especially for wind and solar modeled at 356 resource regions. In this paper we perform planning studies at three different spatial resolutions--native resolution (134 BAs), state-level, and NERCmore » region level--and evaluate how results change under different levels of spatial aggregation in terms of renewable capacity deployment and location, associated transmission builds, and system costs. The results are used to ascertain the value of high geographically resolved models in terms of their impact on relative competitiveness among renewable energy resources.« less
NASA Astrophysics Data System (ADS)
Marchand, Paul J.; Szlag, Daniel; Bouwens, Arno; Lasser, Theo
2018-03-01
Visible light optical coherence tomography has shown great interest in recent years for spectroscopic and high-resolution retinal and cerebral imaging. Here, we present an extended-focus optical coherence microscopy system operating from the visible to the near-infrared wavelength range for high axial and lateral resolution imaging of cortical structures in vivo. The system exploits an ultrabroad illumination spectrum centered in the visible wavelength range (λc = 650 nm, Δλ ˜ 250 nm) offering a submicron axial resolution (˜0.85 μm in water) and an extended-focus configuration providing a high lateral resolution of ˜1.4 μm maintained over ˜150 μm in depth in water. The system's axial and lateral resolution are first characterized using phantoms, and its imaging performance is then demonstrated by imaging the vasculature, myelinated axons, and neuronal cells in the first layers of the somatosensory cortex of mice in vivo.
& Legislation Links Discussion Lists Quick Links AAPT eMentoring ComPADRE Review of High School Take Physics" Poster Why Physics Poster Thumbnail Download normal resolution JPEG Download high resolution JPEG Download Spanish Version Recruiting Physics Students in High School (FED newsletter article
ERIC Educational Resources Information Center
Jones, Corinne A.; Hoffman, Matthew R.; Geng, Zhixian; Abdelhalim, Suzan M.; Jiang, Jack J.; McCulloch, Timothy M.
2014-01-01
Purpose: The purpose of this study was to investigate inter- and intrarater reliability among expert users, novice users, and speech-language pathologists with a semiautomated high-resolution manometry analysis program. We hypothesized that all users would have high intrarater reliability and high interrater reliability. Method: Three expert…
High Speed and High Spatial Density Parameter Measurement Using Fiber Optic Sensing Technology
NASA Technical Reports Server (NTRS)
Richards, William Lance (Inventor); Piazza, Anthony (Inventor); Parker, Allen R. Jr. (Inventor); Hamory, Philip J (Inventor); Chan, Hon Man (Inventor)
2017-01-01
The present invention is an improved fiber optic sensing system (FOSS) having the ability to provide both high spatial resolution and high frequency strain measurements. The inventive hybrid FOSS fiber combines sensors from high acquisition speed and low spatial resolution Wavelength-Division Multiplexing (WDM) systems and from low acquisition speed and high spatial resolution Optical Frequency Domain Reflection (OFDR) systems. Two unique light sources utilizing different wavelengths are coupled with the hybrid FOSS fiber to generate reflected data from both the WDM sensors and OFDR sensors operating on a single fiber optic cable without incurring interference from one another. The two data sets are then de-multiplexed for analysis, optionally with conventionally-available WDM and OFDR system analyzers.
Larsson, Daniel H; Lundström, Ulf; Westermark, Ulrica K; Arsenian Henriksson, Marie; Burvall, Anna; Hertz, Hans M
2013-02-01
Small-animal studies require images with high spatial resolution and high contrast due to the small scale of the structures. X-ray imaging systems for small animals are often limited by the microfocus source. Here, the authors investigate the applicability of liquid-metal-jet x-ray sources for such high-resolution small-animal imaging, both in tomography based on absorption and in soft-tissue tumor imaging based on in-line phase contrast. The experimental arrangement consists of a liquid-metal-jet x-ray source, the small-animal object on a rotating stage, and an imaging detector. The source-to-object and object-to-detector distances are adjusted for the preferred contrast mechanism. Two different liquid-metal-jet sources are used, one circulating a Ga∕In∕Sn alloy and the other an In∕Ga alloy for higher penetration through thick tissue. Both sources are operated at 40-50 W electron-beam power with ∼7 μm x-ray spots, providing high spatial resolution in absorption imaging and high spatial coherence for the phase-contrast imaging. High-resolution absorption imaging is demonstrated on mice with CT, showing 50 μm bone details in the reconstructed slices. High-resolution phase-contrast soft-tissue imaging shows clear demarcation of mm-sized tumors at much lower dose than is required in absorption. This is the first application of liquid-metal-jet x-ray sources for whole-body small-animal x-ray imaging. In absorption, the method allows high-resolution tomographic skeletal imaging with potential for significantly shorter exposure times due to the power scalability of liquid-metal-jet sources. In phase contrast, the authors use a simple in-line arrangement to show distinct tumor demarcation of few-mm-sized tumors. This is, to their knowledge, the first small-animal tumor visualization with a laboratory phase-contrast system.
NASA Astrophysics Data System (ADS)
Hester, David Barry
The objective of this research was to develop methods for urban land cover analysis using QuickBird high spatial resolution satellite imagery. Such imagery has emerged as a rich commercially available remote sensing data source and has enjoyed high-profile broadcast news media and Internet applications, but methods of quantitative analysis have not been thoroughly explored. The research described here consists of three studies focused on the use of pan-sharpened 61-cm spatial resolution QuickBird imagery, the spatial resolution of which is the highest of any commercial satellite. In the first study, a per-pixel land cover classification method is developed for use with this imagery. This method utilizes a per-pixel classification approach to generate an accurate six-category high spatial resolution land cover map of a developing suburban area. The primary objective of the second study was to develop an accurate land cover change detection method for use with QuickBird land cover products. This work presents an efficient fuzzy framework for transforming map uncertainty into accurate and meaningful high spatial resolution land cover change analysis. The third study described here is an urban planning application of the high spatial resolution QuickBird-based land cover product developed in the first study. This work both meaningfully connects this exciting new data source to urban watershed management and makes an important empirical contribution to the study of suburban watersheds. Its analysis of residential roads and driveways as well as retail parking lots sheds valuable light on the impact of transportation-related land use on the suburban landscape. Broadly, these studies provide new methods for using state-of-the-art remote sensing data to inform land cover analysis and urban planning. These methods are widely adaptable and produce land cover products that are both meaningful and accurate. As additional high spatial resolution satellites are launched and the cost of high resolution imagery continues to decline, this research makes an important contribution to this exciting era in the science of remote sensing.
Roberts, N.A.; Noh, J.H.; Lassiter, M.G.; Guo, S.; Kalinin, S.V.; Rack, P.D.
2012-01-01
High resolution and isolated scanning probe microscopy (SPM) is in demand for continued development of energy storage and conversion systems involving chemical reactions at the nanoscale as well as an improved understanding of biological systems. Carbon nanotubes (CNTs) have large aspect ratios and, if leveraged properly, can be used to develop high resolution SPM probes. Isolation of SPM probes can be achieved by deposited a dielectric film and selectively etching at the apex of the probe. In this paper the fabrication of a high resolution and isolated SPM tip is demonstrated using electron beam induced etching of a dielectric film deposited onto an SPM tip with an attached CNT at the apex. PMID:22433664
Roberts, N A; Noh, J H; Lassiter, M G; Guo, S; Kalinin, S V; Rack, P D
2012-04-13
High resolution and isolated scanning probe microscopy (SPM) is in demand for continued development of energy storage and conversion systems involving chemical reactions at the nanoscale as well as an improved understanding of biological systems. Carbon nanotubes (CNTs) have large aspect ratios and, if leveraged properly, can be used to develop high resolution SPM probes. Isolation of SPM probes can be achieved by depositing a dielectric film and selectively etching at the apex of the probe. In this paper the fabrication of a high resolution and isolated SPM tip is demonstrated using electron beam induced etching of a dielectric film deposited onto an SPM tip with an attached CNT at the apex.
NASA Technical Reports Server (NTRS)
Tarbell, Theodore D.
1993-01-01
Technical studies of the feasibility of balloon flights of the former Spacelab instrument, the Solar Optical Universal Polarimeter, with a modern charge-coupled device (CCD) camera, to study the structure and evolution of solar active regions at high resolution, are reviewed. In particular, different CCD cameras were used at ground-based solar observatories with the SOUP filter, to evaluate their performance and collect high resolution images. High resolution movies of the photosphere and chromosphere were successfully obtained using four different CCD cameras. Some of this data was collected in coordinated observations with the Yohkoh satellite during May-July, 1992, and they are being analyzed scientifically along with simultaneous X-ray observations.
High-Resolution Adaptive Optics Test-Bed for Vision Science
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wilks, S C; Thomspon, C A; Olivier, S S
2001-09-27
We discuss the design and implementation of a low-cost, high-resolution adaptive optics test-bed for vision research. It is well known that high-order aberrations in the human eye reduce optical resolution and limit visual acuity. However, the effects of aberration-free eyesight on vision are only now beginning to be studied using adaptive optics to sense and correct the aberrations in the eye. We are developing a high-resolution adaptive optics system for this purpose using a Hamamatsu Parallel Aligned Nematic Liquid Crystal Spatial Light Modulator. Phase-wrapping is used to extend the effective stroke of the device, and the wavefront sensing and wavefrontmore » correction are done at different wavelengths. Issues associated with these techniques will be discussed.« less
High resolution digital delay timer
Martin, Albert D.
1988-01-01
Method and apparatus are provided for generating an output pulse following a trigger pulse at a time delay interval preset with a resolution which is high relative to a low resolution available from supplied clock pulses. A first lumped constant delay (20) provides a first output signal (24) at predetermined interpolation intervals corresponding to the desired high resolution time interval. Latching circuits (26, 28) latch the high resolution data (24) to form a first synchronizing data set (60). A selected time interval has been preset to internal counters (142, 146, 154) and corrected for circuit propagation delay times having the same order of magnitude as the desired high resolution. Internal system clock pulses (32, 34) count down the counters to generate an internal pulse delayed by an interval which is functionally related to the preset time interval. A second LCD (184) corrects the internal signal with the high resolution time delay. A second internal pulse is then applied to a third LCD (74) to generate a second set of synchronizing data (76) which is complementary with the first set of synchronizing data (60) for presentation to logic circuits (64). The logic circuits (64) further delay the internal output signal (72) to obtain a proper phase relationship of an output signal (80) with the internal pulses (32, 34). The final delayed output signal (80) thereafter enables the output pulse generator (82) to produce the desired output pulse (84) at the preset time delay interval following input of the trigger pulse (10, 12).
Extension of least squares spectral resolution algorithm to high-resolution lipidomics data.
Zeng, Ying-Xu; Mjøs, Svein Are; David, Fabrice P A; Schmid, Adrien W
2016-03-31
Lipidomics, which focuses on the global study of molecular lipids in biological systems, has been driven tremendously by technical advances in mass spectrometry (MS) instrumentation, particularly high-resolution MS. This requires powerful computational tools that handle the high-throughput lipidomics data analysis. To address this issue, a novel computational tool has been developed for the analysis of high-resolution MS data, including the data pretreatment, visualization, automated identification, deconvolution and quantification of lipid species. The algorithm features the customized generation of a lipid compound library and mass spectral library, which covers the major lipid classes such as glycerolipids, glycerophospholipids and sphingolipids. Next, the algorithm performs least squares resolution of spectra and chromatograms based on the theoretical isotope distribution of molecular ions, which enables automated identification and quantification of molecular lipid species. Currently, this methodology supports analysis of both high and low resolution MS as well as liquid chromatography-MS (LC-MS) lipidomics data. The flexibility of the methodology allows it to be expanded to support more lipid classes and more data interpretation functions, making it a promising tool in lipidomic data analysis. Copyright © 2016 Elsevier B.V. All rights reserved.
Circuit for high resolution decoding of multi-anode microchannel array detectors
NASA Technical Reports Server (NTRS)
Kasle, David B. (Inventor)
1995-01-01
A circuit for high resolution decoding of multi-anode microchannel array detectors consisting of input registers accepting transient inputs from the anode array; anode encoding logic circuits connected to the input registers; midpoint pipeline registers connected to the anode encoding logic circuits; and pixel decoding logic circuits connected to the midpoint pipeline registers is described. A high resolution algorithm circuit operates in parallel with the pixel decoding logic circuit and computes a high resolution least significant bit to enhance the multianode microchannel array detector's spatial resolution by halving the pixel size and doubling the number of pixels in each axis of the anode array. A multiplexer is connected to the pixel decoding logic circuit and allows a user selectable pixel address output according to the actual multi-anode microchannel array detector anode array size. An output register concatenates the high resolution least significant bit onto the standard ten bit pixel address location to provide an eleven bit pixel address, and also stores the full eleven bit pixel address. A timing and control state machine is connected to the input registers, the anode encoding logic circuits, and the output register for managing the overall operation of the circuit.
Fabrication of Ultrasensitive TES Bolometric Detectors for HIRMES
NASA Astrophysics Data System (ADS)
Brown, Ari-David; Brekosky, Regis; Franz, David; Hsieh, Wen-Ting; Kutyrev, Alexander; Mikula, Vilem; Miller, Timothy; Moseley, S. Harvey; Oxborrow, Joseph; Rostem, Karwan; Wollack, Edward
2018-04-01
The high-resolution mid-infrared spectrometer (HIRMES) is a high resolving power (R 100,000) instrument operating in the 25-122 μm spectral range and will fly on board the Stratospheric Observatory for Far-Infrared Astronomy in 2019. Central to HIRMES are its two transition edge sensor (TES) bolometric cameras, an 8 × 16 detector high-resolution array and a 64 × 16 detector low-resolution array. Both types of detectors consist of Mo/Au TES fabricated on leg-isolated Si membranes. Whereas the high-resolution detectors, with a noise equivalent power (NEP) 1.5 × 10-18 W/rt (Hz), are fabricated on 0.45 μm Si substrates, the low-resolution detectors, with NEP 1.0 × 10-17 W/rt (Hz), are fabricated on 1.40 μm Si. Here, we discuss the similarities and differences in the fabrication methodologies used to realize the two types of detectors.
Panretinal, high-resolution color photography of the mouse fundus.
Paques, Michel; Guyomard, Jean-Laurent; Simonutti, Manuel; Roux, Michel J; Picaud, Serge; Legargasson, Jean-François; Sahel, José-Alain
2007-06-01
To analyze high-resolution color photographs of the mouse fundus. A contact fundus camera based on topical endoscopy fundus imaging (TEFI) was built. Fundus photographs of C57 and Balb/c mice obtained by TEFI were qualitatively analyzed. High-resolution digital imaging of the fundus, including the ciliary body, was routinely obtained. The reflectance and contrast of retinal vessels varied significantly with the amount of incident and reflected light and, thus, with the degree of fundus pigmentation. The combination of chromatic and spherical aberration favored blue light imaging, in term of both field and contrast. TEFI is a small, low-cost system that allows high-resolution color fundus imaging and fluorescein angiography in conscious mice. Panretinal imaging is facilitated by the presence of the large rounded lens. TEFI significantly improves the quality of in vivo photography of retina and ciliary process of mice. Resolution is, however, affected by chromatic aberration, and should be improved by monochromatic imaging.
NASA Astrophysics Data System (ADS)
Pani, R.; Gonzalez, A. J.; Bettiol, M.; Fabbri, A.; Cinti, M. N.; Preziosi, E.; Borrazzo, C.; Conde, P.; Pellegrini, R.; Di Castro, E.; Majewski, S.
2015-06-01
The proposal of Mindview European Project concerns with the development of a very high resolution and high efficiency brain dedicated PET scanner simultaneously working with a Magnetic Resonance scanner, that expects to visualize neurotransmitter pathways and their disruptions in the quest to better diagnose schizophrenia. On behalf of this project, we propose a low cost PET module for the first prototype, based on monolithic crystals, suitable to be integrated with a head Radio Frequency (RF) coil. The aim of the suggested module is to achieve high performances in terms of efficiency, planar spatial resolution (expected about 1 mm) and discrimination of gamma Depth Of Interaction (DOI) in order to reduce the parallax error. Our preliminary results are very promising: a DOI resolution of about 3 mm, a spatial resolution ranging from about 1 to 1.5 mm and a good position linearity.
Numerical Simulation and Mechanical Design for TPS Electron Beam Position Monitors
NASA Astrophysics Data System (ADS)
Hsueh, H. P.; Kuan, C. K.; Ueng, T. S.; Hsiung, G. Y.; Chen, J. R.
2007-01-01
Comprehensive study on the mechanical design and numerical simulation for the high resolution electron beam position monitors are key steps to build the newly proposed 3rd generation synchrotron radiation research facility, Taiwan Photon Source (TPS). With more advanced electromagnetic simulation tool like MAFIA tailored specifically for particle accelerator, the design for the high resolution electron beam position monitors can be tested in such environment before they are experimentally tested. The design goal of our high resolution electron beam position monitors is to get the best resolution through sensitivity and signal optimization. The definitions and differences between resolution and sensitivity of electron beam position monitors will be explained. The design consideration is also explained. Prototype deign has been carried out and the related simulations were also carried out with MAFIA. The results are presented here. Sensitivity as high as 200 in x direction has been achieved in x direction at 500 MHz.
Two-photon imaging of spatially extended neuronal network dynamics with high temporal resolution.
Lillis, Kyle P; Eng, Alfred; White, John A; Mertz, Jerome
2008-07-30
We describe a simple two-photon fluorescence imaging strategy, called targeted path scanning (TPS), to monitor the dynamics of spatially extended neuronal networks with high spatiotemporal resolution. Our strategy combines the advantages of mirror-based scanning, minimized dead time, ease of implementation, and compatibility with high-resolution low-magnification objectives. To demonstrate the performance of TPS, we monitor the calcium dynamics distributed across an entire juvenile rat hippocampus (>1.5mm), at scan rates of 100 Hz, with single cell resolution and single action potential sensitivity. Our strategy for fast, efficient two-photon microscopy over spatially extended regions provides a particularly attractive solution for monitoring neuronal population activity in thick tissue, without sacrificing the signal-to-noise ratio or high spatial resolution associated with standard two-photon microscopy. Finally, we provide the code to make our technique generally available.
Fusion of spectral and panchromatic images using false color mapping and wavelet integrated approach
NASA Astrophysics Data System (ADS)
Zhao, Yongqiang; Pan, Quan; Zhang, Hongcai
2006-01-01
With the development of sensory technology, new image sensors have been introduced that provide a greater range of information to users. But as the power limitation of radiation, there will always be some trade-off between spatial and spectral resolution in the image captured by specific sensors. Images with high spatial resolution can locate objects with high accuracy, whereas images with high spectral resolution can be used to identify the materials. Many applications in remote sensing require fusing low-resolution imaging spectral images with panchromatic images to identify materials at high resolution in clutter. A pixel-based false color mapping and wavelet transform integrated fusion algorithm is presented in this paper, the resulting images have a higher information content than each of the original images and retain sensor-specific image information. The simulation results show that this algorithm can enhance the visibility of certain details and preserve the difference of different materials.
Fabrication of Ultrasensitive Transition Edge Sensor Bolometric Detectors for HIRMES
NASA Technical Reports Server (NTRS)
Brown, Ari-David; Brekosky, Regis; Franz, David; Hsieh, Wen-Ting; Kutyrev, Alexander; Mikula, Vilem; Miller, Timothy; Moseley, S. Harvey; Oxborrow, Joseph; Rostem, Karwan;
2017-01-01
The high resolution mid-infrared spectrometer (HIRMES) is a high resolving power (R approx. 100,000) instrument operating in the 25-122 micron spectral range and will fly on board the Stratospheric Observatory for Far-Infrared Astronomy (SOFIA) in 2019. Central ot HIRMES are its two transition edge sensor (TES) bolometric cameras, an 8x16 detector high resolution array and a 64x16 detector low resolution array. Both types of detectors consist of MoAu TES fabricated on leg-isolated Si membranes. Whereas the high resolution detectors, with noise equivalent power (NEP) approx. 2 aW/square root of (Hz), are fabricated on 0.45 micron Si substrates, the low resolution detectors, with NEP approx. 10 aW/square root of (Hz), are fabricated on 1.40 micron Si. Here we discuss the similarities and difference in the fabrication methodologies used to realize the two types of detectors.
NASA Technical Reports Server (NTRS)
Obrien, S. O. (Principal Investigator)
1980-01-01
The program, LACVIN, calculates vegetative indexes numbers on limited area coverage/high resolution picture transmission data for selected IJ grid sections. The IJ grid sections were previously extracted from the full resolution data tapes and stored on disk files.
NASA Astrophysics Data System (ADS)
Yamada, H.; Nishikawa, K.; Honda, M.; Shimura, T.; Akasaka, K.; Tabayashi, K.
2001-02-01
A pressure-resisting cell system has been developed for high-pressure high-resolution nuclear magnetic resonance (NMR) measurements up to a maximum pressure of 600 MPa. This cell system is capable of performing high-pressure experiments with any standard spectrometer, including modern high field NMR machines. A full description of the high-pressure NMR assembly mounted on a 750 MHz spectrometer is presented along with a detailed explanation of the procedure for preparing the pressure-resisting quartz and glass cells.
Ultra-high resolution coded wavefront sensor.
Wang, Congli; Dun, Xiong; Fu, Qiang; Heidrich, Wolfgang
2017-06-12
Wavefront sensors and more general phase retrieval methods have recently attracted a lot of attention in a host of application domains, ranging from astronomy to scientific imaging and microscopy. In this paper, we introduce a new class of sensor, the Coded Wavefront Sensor, which provides high spatio-temporal resolution using a simple masked sensor under white light illumination. Specifically, we demonstrate megapixel spatial resolution and phase accuracy better than 0.1 wavelengths at reconstruction rates of 50 Hz or more, thus opening up many new applications from high-resolution adaptive optics to real-time phase retrieval in microscopy.
NASA Astrophysics Data System (ADS)
Gilra, D. P.; Pwa, T. H.; Arnal, E. M.; de Vries, J.
1982-06-01
In order to process and analyze high resolution IUE data on a large number of interstellar lines in a large number of images for a large number of stars, computer programs were developed for 115 lines in the short wavelength range and 40 in the long wavelength range. Programs include extraction, processing, plotting, averaging, and profile fitting. Wavelength calibration in high resolution spectra, fixed pattern noise, instrument profile and resolution, and the background problem in the region where orders are crowding are discussed. All the expected lines are detected in at least one spectrum.
Reproducibility and calibration of MMC-based high-resolution gamma detectors
Bates, C. R.; Pies, C.; Kempf, S.; ...
2016-07-15
Here, we describe a prototype γ-ray detector based on a metallic magnetic calorimeter with an energy resolution of 46 eV at 60 keV and a reproducible response function that follows a simple second-order polynomial. The simple detector calibration allows adding high-resolution spectra from different pixels and different cool-downs without loss in energy resolution to determine γ-ray centroids with high accuracy. As an example of an application in nuclear safeguards enabled by such a γ-ray detector, we discuss the non-destructive assay of 242Pu in a mixed-isotope Pu sample.
Spatial resolution limitation of liquid crystal spatial light modulator
NASA Astrophysics Data System (ADS)
Wang, Xinghua; Wang, Bin; McManamon, Paul F., III; Pouch, John J.; Miranda, Felix A.; Anderson, James E.; Bos, Philip J.
2004-10-01
The effect of fringing electric fields in a liquid crystal (LC) Optical Phased Array (OPA), also referred to as a spatial light modulator (SLM), is a governing factor that determines the diffraction efficiency (DE) of the LC OPA for high resolution spatial phase modulation. In this article, the fringing field effect in a high resolution LC OPA is studied by accurate modeling the DE of the LC blazed gratings by LC director simulation and Finite Difference Time Domain (FDTD) simulation. Influence factors that contribute significantly to the DE are discussed. Such results provide fundamental understanding for high resolution LC devices.
NASA Technical Reports Server (NTRS)
Byer, R. L.
1982-01-01
The measurement of high resolution pulsed and continuous wave (CW) coherent anti-Stokes Raman spectroscopy (CARS) measurements in pulsed and steady state supersonic expansions were demonstrated. Pulsed molecular beam sources were characterized, and saturation of a Raman transition and, for the first time, the Raman spectrum of a complex molecular cluster were observed. The observation of CW CARS spectra in a molecular expansion and the effects of transit time broadening is described. Supersonic expansion is established as a viable technique for high resolution Raman spectroscopy of cold molecules with resolutions of 100 MH2.
The high-resolution spectrum of the pulsating, pre-white dwarf star PG 1159-035 (GW VIR)
NASA Technical Reports Server (NTRS)
Liebert, James; Wesemael, F.; Husfeld, D.; Wehrse, R.; Starrfield, S. G.
1989-01-01
High-resolution and low-resolution UV spectra and a high-resolution optical spectrum were obtained for PG 1159-035, revealing apparent photospheric absorption features with defined cores from N V 1240 A, N IV 1270 A, O V 1371 A, and C IV 1550 A. The photospheric velocity derived using all of these lines except for C IV is about +35 km/s. Equivalent-width measurements determined for all of the features may provide a tighter constraint on the photospheric temperature in a detailed model atmosphere analysis treating the CNO ions.
Fast prototyping of high-aspect ratio, high-resolution x-ray masks by gas-assisted focused ion beam
NASA Technical Reports Server (NTRS)
Hartley, F.; Malek, C.; Neogi, J.
2001-01-01
The capacity of chemically-assisted focused ion beam (fib) etching systems to undertake direct and highly anisotropic erosion of thin and thick gold (or other high atomic number [Z])coatings on x-ray mask membranes/substrates provides new levels of precision, flexibility, simplification and rapidity in the manufacture of mask absorber patterns, allowing the fast prototyping of high aspect ratio, high-resolution masks for deep x-ray lithography.
NASA Astrophysics Data System (ADS)
Tanabe, Hiroshi; Koike, Hideya; Hatano, Hironori; Hayashi, Takumi; Cao, Qinghong; Himeno, Shunichi; Kaneda, Taishi; Akimitsu, Moe; Sawada, Asuka; Ono, Yasushi
2017-10-01
A new type of high-throughput/high-resolution 96CH ion Doppler tomography diagnostics has been developed using ``multi-slit'' spectroscopy technique for detailed investigation of fine structure formation during high guide field magnetic reconnection. In the last three years, high field merging experiment in MAST pioneered new frontiers of reconnection heating: formation of highly peaked structure around X-point in high guide field condition (Bt > 0.3 T), outflow dissipation under the influence of better plasma confinement to form high temperature ring structure which aligns with closed flux surface of toroidal plasma, and interaction between ion and electron temperature profile during transport/confinement phase to form triple peak structure (τeiE 4 ms). To investigate more detailed mechanism with in-situ magnetic measurement, the university of Tokyo starts the upgrade of plasma parameters and spatial resolution of optical diagnostics as in MAST. Now, a new type of high-throughput/high-resolution 96CH ion Doppler tomography diagnostics system construction has been completed and it successfully resolved fine structure of ion heating downstream, aligned with closed flux surface formed by reconnected field. This work was supported by JSPS KAKENHI Grant Numbers 15H05750, 15K14279 and 17H04863.
NASA Astrophysics Data System (ADS)
Tang, U. W.; Wang, Z. S.
2008-10-01
Each city has its unique urban form. The importance of urban form on sustainable development has been recognized in recent years. Traditionally, air quality modelling in a city is in a mesoscale with grid resolution of kilometers, regardless of its urban form. This paper introduces a GIS-based air quality and noise model system developed to study the built environment of highly compact urban forms. Compared with traditional mesoscale air quality model system, the present model system has a higher spatial resolution down to individual buildings along both sides of the street. Applying the developed model system in the Macao Peninsula with highly compact urban forms, the average spatial resolution of input and output data is as high as 174 receptor points per km2. Based on this input/output dataset with a high spatial resolution, this study shows that even the highly compact urban forms can be fragmented into a very small geographic scale of less than 3 km2. This is due to the significant temporal variation of urban development. The variation of urban form in each fragment in turn affects air dispersion, traffic condition, and thus air quality and noise in a measurable scale.
Okutan, Leyla; Kongstad, Kenneth T; Jäger, Anna K; Staerk, Dan
2014-11-26
Type 2 diabetes affects millions of people worldwide, and new improved drugs or functional foods containing selective α-amylase inhibitors are needed for improved management of blood glucose. In this article the development of a microplate-based high-resolution α-amylase inhibition assay with direct photometric measurement of α-amylase activity is described. The inhibition assay is based on porcine pancreatic α-amylase with 2-chloro-4-nitrophenyl-α-D-maltotriose as substrate, which this gives a stable, sensitive, and cheap inhibition assay as requested for high-resolution purposes. In combination with HPLC-HRMS-SPE-NMR, this provides an analytical platform that allows simultaneous chemical and biological profiling of α-amylase inhibitors in plant extracts. Proof-of-concept with an artificial mixture of six compounds-of which three are known α-amylase inhibitors-showed that the high-resolution α-amylase inhibition profiles allowed detection of sub-microgram amounts of the α-amylase inhibitors. Furthermore, the high-resolution α-amylase inhibition assay/HPLC-HRMS-SPE-NMR platform allowed identification of cinnamaldehyde as the α-amylase inhibitor in cinnamon (Cinnamomum verum Presl.).
NASA Astrophysics Data System (ADS)
Benhalouche, Fatima Zohra; Karoui, Moussa Sofiane; Deville, Yannick; Ouamri, Abdelaziz
2017-04-01
This paper proposes three multisharpening approaches to enhance the spatial resolution of urban hyperspectral remote sensing images. These approaches, related to linear-quadratic spectral unmixing techniques, use a linear-quadratic nonnegative matrix factorization (NMF) multiplicative algorithm. These methods begin by unmixing the observable high-spectral/low-spatial resolution hyperspectral and high-spatial/low-spectral resolution multispectral images. The obtained high-spectral/high-spatial resolution features are then recombined, according to the linear-quadratic mixing model, to obtain an unobservable multisharpened high-spectral/high-spatial resolution hyperspectral image. In the first designed approach, hyperspectral and multispectral variables are independently optimized, once they have been coherently initialized. These variables are alternately updated in the second designed approach. In the third approach, the considered hyperspectral and multispectral variables are jointly updated. Experiments, using synthetic and real data, are conducted to assess the efficiency, in spatial and spectral domains, of the designed approaches and of linear NMF-based approaches from the literature. Experimental results show that the designed methods globally yield very satisfactory spectral and spatial fidelities for the multisharpened hyperspectral data. They also prove that these methods significantly outperform the used literature approaches.
Cheng, Bingbing; Bandi, Venugopal; Wei, Ming-Yuan; Pei, Yanbo; D’Souza, Francis; Nguyen, Kytai T.; Hong, Yi; Yuan, Baohong
2016-01-01
For many years, investigators have sought after high-resolution fluorescence imaging in centimeter-deep tissue because many interesting in vivo phenomena—such as the presence of immune system cells, tumor angiogenesis, and metastasis—may be located deep in tissue. Previously, we developed a new imaging technique to achieve high spatial resolution in sub-centimeter deep tissue phantoms named continuous-wave ultrasound-switchable fluorescence (CW-USF). The principle is to use a focused ultrasound wave to externally and locally switch on and off the fluorophore emission from a small volume (close to ultrasound focal volume). By making improvements in three aspects of this technique: excellent near-infrared USF contrast agents, a sensitive frequency-domain USF imaging system, and an effective signal processing algorithm, for the first time this study has achieved high spatial resolution (~ 900 μm) in 3-centimeter-deep tissue phantoms with high signal-to-noise ratio (SNR) and high sensitivity (3.4 picomoles of fluorophore in a volume of 68 nanoliters can be detected). We have achieved these results in both tissue-mimic phantoms and porcine muscle tissues. We have also demonstrated multi-color USF to image and distinguish two fluorophores with different wavelengths, which might be very useful for simultaneously imaging of multiple targets and observing their interactions in the future. This work has opened the door for future studies of high-resolution centimeter-deep tissue fluorescence imaging. PMID:27829050
Cheng, Bingbing; Bandi, Venugopal; Wei, Ming-Yuan; Pei, Yanbo; D'Souza, Francis; Nguyen, Kytai T; Hong, Yi; Yuan, Baohong
2016-01-01
For many years, investigators have sought after high-resolution fluorescence imaging in centimeter-deep tissue because many interesting in vivo phenomena-such as the presence of immune system cells, tumor angiogenesis, and metastasis-may be located deep in tissue. Previously, we developed a new imaging technique to achieve high spatial resolution in sub-centimeter deep tissue phantoms named continuous-wave ultrasound-switchable fluorescence (CW-USF). The principle is to use a focused ultrasound wave to externally and locally switch on and off the fluorophore emission from a small volume (close to ultrasound focal volume). By making improvements in three aspects of this technique: excellent near-infrared USF contrast agents, a sensitive frequency-domain USF imaging system, and an effective signal processing algorithm, for the first time this study has achieved high spatial resolution (~ 900 μm) in 3-centimeter-deep tissue phantoms with high signal-to-noise ratio (SNR) and high sensitivity (3.4 picomoles of fluorophore in a volume of 68 nanoliters can be detected). We have achieved these results in both tissue-mimic phantoms and porcine muscle tissues. We have also demonstrated multi-color USF to image and distinguish two fluorophores with different wavelengths, which might be very useful for simultaneously imaging of multiple targets and observing their interactions in the future. This work has opened the door for future studies of high-resolution centimeter-deep tissue fluorescence imaging.
Kok, H P; de Greef, M; Bel, A; Crezee, J
2009-08-01
In regional hyperthermia, optimization is useful to obtain adequate applicator settings. A speed-up of the previously published method for high resolution temperature based optimization is proposed. Element grouping as described in literature uses selected voxel sets instead of single voxels to reduce computation time. Elements which achieve their maximum heating potential for approximately the same phase/amplitude setting are grouped. To form groups, eigenvalues and eigenvectors of precomputed temperature matrices are used. At high resolution temperature matrices are unknown and temperatures are estimated using low resolution (1 cm) computations and the high resolution (2 mm) temperature distribution computed for low resolution optimized settings using zooming. This technique can be applied to estimate an upper bound for high resolution eigenvalues. The heating potential of elements was estimated using these upper bounds. Correlations between elements were estimated with low resolution eigenvalues and eigenvectors, since high resolution eigenvectors remain unknown. Four different grouping criteria were applied. Constraints were set to the average group temperatures. Element grouping was applied for five patients and optimal settings for the AMC-8 system were determined. Without element grouping the average computation times for five and ten runs were 7.1 and 14.4 h, respectively. Strict grouping criteria were necessary to prevent an unacceptable exceeding of the normal tissue constraints (up to approximately 2 degrees C), caused by constraining average instead of maximum temperatures. When strict criteria were applied, speed-up factors of 1.8-2.1 and 2.6-3.5 were achieved for five and ten runs, respectively, depending on the grouping criteria. When many runs are performed, the speed-up factor will converge to 4.3-8.5, which is the average reduction factor of the constraints and depends on the grouping criteria. Tumor temperatures were comparable. Maximum exceeding of the constraint in a hot spot was 0.24-0.34 degree C; average maximum exceeding over all five patients was 0.09-0.21 degree C, which is acceptable. High resolution temperature based optimization using element grouping can achieve a speed-up factor of 4-8, without large deviations from the conventional method.
Architecture and applications of a high resolution gated SPAD image sensor
Burri, Samuel; Maruyama, Yuki; Michalet, Xavier; Regazzoni, Francesco; Bruschini, Claudio; Charbon, Edoardo
2014-01-01
We present the architecture and three applications of the largest resolution image sensor based on single-photon avalanche diodes (SPADs) published to date. The sensor, fabricated in a high-voltage CMOS process, has a resolution of 512 × 128 pixels and a pitch of 24 μm. The fill-factor of 5% can be increased to 30% with the use of microlenses. For precise control of the exposure and for time-resolved imaging, we use fast global gating signals to define exposure windows as small as 4 ns. The uniformity of the gate edges location is ∼140 ps (FWHM) over the whole array, while in-pixel digital counting enables frame rates as high as 156 kfps. Currently, our camera is used as a highly sensitive sensor with high temporal resolution, for applications ranging from fluorescence lifetime measurements to fluorescence correlation spectroscopy and generation of true random numbers. PMID:25090572
Dedicated mobile high resolution prostate PET imager with an insertable transrectal probe
Majewski, Stanislaw; Proffitt, James
2010-12-28
A dedicated mobile PET imaging system to image the prostate and surrounding organs. The imaging system includes an outside high resolution PET imager placed close to the patient's torso and an insertable and compact transrectal probe that is placed in close proximity to the prostate and operates in conjunction with the outside imager. The two detector systems are spatially co-registered to each other. The outside imager is mounted on an open rotating gantry to provide torso-wide 3D images of the prostate and surrounding tissue and organs. The insertable probe provides closer imaging, high sensitivity, and very high resolution predominately 2D view of the prostate and immediate surroundings. The probe is operated in conjunction with the outside imager and a fast data acquisition system to provide very high resolution reconstruction of the prostate and surrounding tissue and organs.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Andersen, T.; Jensen, R.; Christensen, M. K.
2012-07-15
We demonstrate a combined microreactor and time of flight system for testing and characterization of heterogeneous catalysts with high resolution mass spectrometry and high sensitivity. Catalyst testing is performed in silicon-based microreactors which have high sensitivity and fast thermal response. Gas analysis is performed with a time of flight mass spectrometer with a modified nude Bayard-Alpert ionization gauge as gas ionization source. The mass resolution of the time of flight mass spectrometer using the ion gauge as ionization source is estimated to m/{Delta}m > 2500. The system design is superior to conventional batch and flow reactors with accompanying product detectionmore » by quadrupole mass spectrometry or gas chromatography not only due to the high sensitivity, fast temperature response, high mass resolution, and fast acquisition time of mass spectra but it also allows wide mass range (0-5000 amu in the current configuration). As a demonstration of the system performance we present data from ammonia oxidation on a Pt thin film showing resolved spectra of OH and NH{sub 3}.« less
NASA Astrophysics Data System (ADS)
Andersen, T.; Jensen, R.; Christensen, M. K.; Pedersen, T.; Hansen, O.; Chorkendorff, I.
2012-07-01
We demonstrate a combined microreactor and time of flight system for testing and characterization of heterogeneous catalysts with high resolution mass spectrometry and high sensitivity. Catalyst testing is performed in silicon-based microreactors which have high sensitivity and fast thermal response. Gas analysis is performed with a time of flight mass spectrometer with a modified nude Bayard-Alpert ionization gauge as gas ionization source. The mass resolution of the time of flight mass spectrometer using the ion gauge as ionization source is estimated to m/Δm > 2500. The system design is superior to conventional batch and flow reactors with accompanying product detection by quadrupole mass spectrometry or gas chromatography not only due to the high sensitivity, fast temperature response, high mass resolution, and fast acquisition time of mass spectra but it also allows wide mass range (0-5000 amu in the current configuration). As a demonstration of the system performance we present data from ammonia oxidation on a Pt thin film showing resolved spectra of OH and NH3.
Andersen, T; Jensen, R; Christensen, M K; Pedersen, T; Hansen, O; Chorkendorff, I
2012-07-01
We demonstrate a combined microreactor and time of flight system for testing and characterization of heterogeneous catalysts with high resolution mass spectrometry and high sensitivity. Catalyst testing is performed in silicon-based microreactors which have high sensitivity and fast thermal response. Gas analysis is performed with a time of flight mass spectrometer with a modified nude Bayard-Alpert ionization gauge as gas ionization source. The mass resolution of the time of flight mass spectrometer using the ion gauge as ionization source is estimated to m/Δm > 2500. The system design is superior to conventional batch and flow reactors with accompanying product detection by quadrupole mass spectrometry or gas chromatography not only due to the high sensitivity, fast temperature response, high mass resolution, and fast acquisition time of mass spectra but it also allows wide mass range (0-5000 amu in the current configuration). As a demonstration of the system performance we present data from ammonia oxidation on a Pt thin film showing resolved spectra of OH and NH(3).
High Resolution Model Intercomparison Project (HighResMIP v1.0) for CMIP6
NASA Astrophysics Data System (ADS)
Haarsma, Reindert J.; Roberts, Malcolm J.; Vidale, Pier Luigi; Senior, Catherine A.; Bellucci, Alessio; Bao, Qing; Chang, Ping; Corti, Susanna; Fučkar, Neven S.; Guemas, Virginie; von Hardenberg, Jost; Hazeleger, Wilco; Kodama, Chihiro; Koenigk, Torben; Leung, L. Ruby; Lu, Jian; Luo, Jing-Jia; Mao, Jiafu; Mizielinski, Matthew S.; Mizuta, Ryo; Nobre, Paulo; Satoh, Masaki; Scoccimarro, Enrico; Semmler, Tido; Small, Justin; von Storch, Jin-Song
2016-11-01
Robust projections and predictions of climate variability and change, particularly at regional scales, rely on the driving processes being represented with fidelity in model simulations. The role of enhanced horizontal resolution in improved process representation in all components of the climate system is of growing interest, particularly as some recent simulations suggest both the possibility of significant changes in large-scale aspects of circulation as well as improvements in small-scale processes and extremes. However, such high-resolution global simulations at climate timescales, with resolutions of at least 50 km in the atmosphere and 0.25° in the ocean, have been performed at relatively few research centres and generally without overall coordination, primarily due to their computational cost. Assessing the robustness of the response of simulated climate to model resolution requires a large multi-model ensemble using a coordinated set of experiments. The Coupled Model Intercomparison Project 6 (CMIP6) is the ideal framework within which to conduct such a study, due to the strong link to models being developed for the CMIP DECK experiments and other model intercomparison projects (MIPs). Increases in high-performance computing (HPC) resources, as well as the revised experimental design for CMIP6, now enable a detailed investigation of the impact of increased resolution up to synoptic weather scales on the simulated mean climate and its variability. The High Resolution Model Intercomparison Project (HighResMIP) presented in this paper applies, for the first time, a multi-model approach to the systematic investigation of the impact of horizontal resolution. A coordinated set of experiments has been designed to assess both a standard and an enhanced horizontal-resolution simulation in the atmosphere and ocean. The set of HighResMIP experiments is divided into three tiers consisting of atmosphere-only and coupled runs and spanning the period 1950-2050, with the possibility of extending to 2100, together with some additional targeted experiments. This paper describes the experimental set-up of HighResMIP, the analysis plan, the connection with the other CMIP6 endorsed MIPs, as well as the DECK and CMIP6 historical simulations. HighResMIP thereby focuses on one of the CMIP6 broad questions, "what are the origins and consequences of systematic model biases?", but we also discuss how it addresses the World Climate Research Program (WCRP) grand challenges.
Ultra-High Spectral Resolution Observations of Fragmentation in Dark Cloud Cores
NASA Technical Reports Server (NTRS)
Velusamy, T.; Langer, W.; Kuiper, T; Levin, S.; Olsen, E.
1993-01-01
This paper presents new evidence of the fragmentary structure of dense cores in dark clouds using the high resolution spectra of the carbon chain molecule CCS transition (J subscript N = 2 subscript 1 - 1 subscript o) at 22.344033 GHz with 0.008 km s superscript -1 resolution.
A high-resolution cattle CNV map by population-scale genome sequencing
USDA-ARS?s Scientific Manuscript database
Copy Number Variations (CNVs) are common genomic structural variations that have been linked to human diseases and phenotypic traits. Prior studies in cattle have produced low-resolution CNV maps. We constructed a draft, high-resolution map of cattle CNVs based on whole genome sequencing data from 7...
Given the relatively high cost of mapping impervious surfaces at regional scales, substantial effort is being expended in the development of moderate-resolution, satellite-based methods for estimating impervious surface area (ISA). To rigorously assess the accuracy of these data ...
USDA-ARS?s Scientific Manuscript database
Many societal applications of soil moisture data products require high spatial resolution and numerical accuracy. Current thermal geostationary satellite sensors (GOES Imager and GOES-R ABI) could produce 2-16km resolution soil moisture proxy data. Passive microwave satellite radiometers (e.g. AMSR...
High quality transmission Kikuchi diffraction analysis of deformed alloys - Case study
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tokarski, Tomasz, E-mail: tokarski@agh.edu.pl
Modern scanning electron microscopes (SEM) equipped with thermally assisted field emission guns (Schottky FEG) are capable of imaging with a resolution in the range of several nanometers or better. Simultaneously, the high electron beam current can be used, which enables fast chemical and crystallographic analysis with a higher resolution than is normally offered by SEM with a tungsten cathode. The current resolution that limits the EDS and EBSD analysis is related to materials' physics, particularly to the electron-specimen interaction volume. The application of thin, electron-transparent specimens, instead of bulk samples, improves the resolution and allows for the detailed analysis ofmore » very fine microstructural features. Beside the typical imaging mode, it is possible to use a standard EBSD camera in such a configuration that only transmitted and scattered electrons are detected. This modern approach was successfully applied to various materials giving rise to significant resolution improvement, especially for the light element magnesium based alloys. This paper presents an insight into the application of the transmission Kikuchi diffraction (TKD) technique applied to the most troublesome, heavily-deformed materials. In particular, the values of the highest possible acquisition rates for high resolution and high quality mapping were estimated within typical imaging conditions of stainless steel and magnesium-yttrium alloy. - Highlights: •Monte Carlo simulations were used to simulate EBSD camera intensity for various measuring conditions. •Transmission Kikuchi diffraction parameters were evaluated for highly deformed, light and heavy elements based alloys. •High quality maps with 20 nm spatial resolution were acquired for Mg and Fe based alloys. •High speed TKD measurements were performed at acquisition rates comparable to the reflection EBSD.« less
High Spectral Resolution, High Cadence, Imaging X-Ray Microcalorimeters for Solar Physics
NASA Technical Reports Server (NTRS)
Bandler, Simon R.; Bailey, Catherine N.; Bookbinder, Jay A.; DeLuca, Edward E.; Chervenak, Jay A.; Eckart, Megan E.; Finkbeiner, Fred M.; Kelley, Daniel P.; Kelley, Richard L.; Kilbourne, Caroline A.;
2010-01-01
High spectral resolution, high cadence, imaging x-ray spectroscopy has the potential to revolutionize the study of the solar corona. To that end we have been developing transition-edge-sensor (TES) based x-ray micro calorimeter arrays for future solar physics missions where imaging and high energy resolution spectroscopy will enable previously impossible studies of the dynamics and energetics of the solar corona. The characteristics of these x-ray microcalorimeters are significantly different from conventional micro calorimeters developed for astrophysics because they need to accommodate much higher count rates (300-1000 cps) while maintaining high energy resolution of less than 4 eV FWHM in the X-ray energy band of 0.2-10 keV. The other main difference is a smaller pixel size (less than 75 x 75 square microns) than is typical for x-ray micro calorimeters in order to provide angular resolution less than 1 arcsecond. We have achieved at energy resolution of 2.15 eV at 6 keV in a pixel with a 12 x 12 square micron TES sensor and 34 x 34 x 9.1 micron gold absorber, and a resolution of 2.30 eV at 6 keV in a pixel with a 35 x 35 micron TES and a 57 x 57 x 9.1 micron gold absorber. This performance has been achieved in pixels that are fabricated directly onto solid substrates, ie. they are not supported by silicon nitride membranes. We present the results from these detectors, the expected performance at high count-rates, and prospects for the use of this technology for future Solar missions.
Robust High-Resolution Cloth Using Parallelism, History-Based Collisions and Accurate Friction
Selle, Andrew; Su, Jonathan; Irving, Geoffrey; Fedkiw, Ronald
2015-01-01
In this paper we simulate high resolution cloth consisting of up to 2 million triangles which allows us to achieve highly detailed folds and wrinkles. Since the level of detail is also influenced by object collision and self collision, we propose a more accurate model for cloth-object friction. We also propose a robust history-based repulsion/collision framework where repulsions are treated accurately and efficiently on a per time step basis. Distributed memory parallelism is used for both time evolution and collisions and we specifically address Gauss-Seidel ordering of repulsion/collision response. This algorithm is demonstrated by several high-resolution and high-fidelity simulations. PMID:19147895
Cryogenic, high-resolution x-ray detector with high count rate capability
Frank, Matthias; Mears, Carl A.; Labov, Simon E.; Hiller, Larry J.; Barfknecht, Andrew T.
2003-03-04
A cryogenic, high-resolution X-ray detector with high count rate capability has been invented. The new X-ray detector is based on superconducting tunnel junctions (STJs), and operates without thermal stabilization at or below 500 mK. The X-ray detector exhibits good resolution (.about.5-20 eV FWHM) for soft X-rays in the keV region, and is capable of counting at count rates of more than 20,000 counts per second (cps). Simple, FET-based charge amplifiers, current amplifiers, or conventional spectroscopy shaping amplifiers can provide the electronic readout of this X-ray detector.
High-quality, daily meteorological data at high spatial resolution are essential for a variety of hydrologic and ecological modeling applications that support environmental risk assessments and decision making. This paper describes the development, application, and assessment of ...
HetMappsS: Heterozygous mapping strategy for high resolution Genotyping-by-Sequencing Markers
USDA-ARS?s Scientific Manuscript database
Reduced representation genotyping approaches, such as genotyping-by-sequencing (GBS), provide opportunities to generate high-resolution genetic maps at a low per-sample cost. However, missing data and non-uniform sequence coverage can complicate map creation in highly heterozygous species. To facili...
TandemPET-A High Resolution, Small Animal, Virtual Pinhole-Based PET Scanner: Initial Design Study
NASA Astrophysics Data System (ADS)
Raylman, Raymond R.; Stolin, Alexander V.; Martone, Peter F.; Smith, Mark F.
2016-02-01
Mice are the perhaps the most common species of rodents used in biomedical research, but many of the current generation of small animal PET scanners are non-optimal for imaging these small rodents due to their relatively low resolution. Consequently, a number of researchers have investigated the development of high-resolution scanners to address this need. In this investigation, the design of a novel, high-resolution system based on the dual-detector, virtual-pinhole PET concept was explored via Monte Carlo simulations. Specifically, this system, called TandemPET, consists of a 5 cm × 5 cm high-resolution detector made-up of a 90 × 90 array of 0.5 mm × 0.5 × 10 mm (pitch = 0.55 mm) LYSO detector elements in coincidence with a lower resolution detector consisting of a 68 × 68 array of 1.5 mm × 1.5 mm × 10 mm LYSO detector elements (total size = 10.5 cm × 10.5 cm). Analyses indicated that TandemPET's optimal geometry is to position the high-resolution detector 3 cm from the center-of-rotation, with the lower resolution detector positioned 9 cm from center. Measurements using modified NEMA NU4-2008-based protocols revealed that the spatial resolution of the system is 0.5 mm FWHM, after correction of positron range effects. Peak sensitivity is 2.1%, which is comparable to current small animal PET scanners. Images from a digital mouse brain phantom demonstrated the potential of the system for identifying important neurological structures.
A new omni-directional multi-camera system for high resolution surveillance
NASA Astrophysics Data System (ADS)
Cogal, Omer; Akin, Abdulkadir; Seyid, Kerem; Popovic, Vladan; Schmid, Alexandre; Ott, Beat; Wellig, Peter; Leblebici, Yusuf
2014-05-01
Omni-directional high resolution surveillance has a wide application range in defense and security fields. Early systems used for this purpose are based on parabolic mirror or fisheye lens where distortion due to the nature of the optical elements cannot be avoided. Moreover, in such systems, the image resolution is limited to a single image sensor's image resolution. Recently, the Panoptic camera approach that mimics the eyes of flying insects using multiple imagers has been presented. This approach features a novel solution for constructing a spherically arranged wide FOV plenoptic imaging system where the omni-directional image quality is limited by low-end sensors. In this paper, an overview of current Panoptic camera designs is provided. New results for a very-high resolution visible spectrum imaging and recording system inspired from the Panoptic approach are presented. The GigaEye-1 system, with 44 single cameras and 22 FPGAs, is capable of recording omni-directional video in a 360°×100° FOV at 9.5 fps with a resolution over (17,700×4,650) pixels (82.3MP). Real-time video capturing capability is also verified at 30 fps for a resolution over (9,000×2,400) pixels (21.6MP). The next generation system with significantly higher resolution and real-time processing capacity, called GigaEye-2, is currently under development. The important capacity of GigaEye-1 opens the door to various post-processing techniques in surveillance domain such as large perimeter object tracking, very-high resolution depth map estimation and high dynamicrange imaging which are beyond standard stitching and panorama generation methods.
Spatial and temporal resolution effects on urban catchments with different imperviousness degrees
NASA Astrophysics Data System (ADS)
Cristiano, Elena; ten Veldhuis, Marie-Claire; van de Giesen, Nick C.
2015-04-01
One of the main problems in urban hydrological analysis is to measure the rainfall at urban scale with high resolution and use these measurements to model urban runoff processes to predict flows and reduce flood risk. With the aim of building a semi-distribute hydrological sewer model for an urban catchment, high resolution rainfall data are required as input. In this study, the sensitivity of hydrological response to high resolution precipitation data for hydrodynamic models at urban scale is evaluated with different combinations of spatial and temporal resolutions. The aim is to study sensitivity in relation to catchment characteristics, especially drainage area size, imperviousness degree and hydraulic properties such as special structures (weirs, pumping stations). Rainfall data of nine storms are considered with 4 different spatial resolutions (3000m, 1000m, 500m and 100m) combined with 4 different temporal resolutions (10min, 5min, 3min and 1min). The dual polarimetric X-band weather radar, located in the Cabauw Experimental Site for Atmospheric Research (CESAR) provided the high resolution rainfall data of these rainfall events, used to improve the sewer model. The effects of spatial-temporal rainfall input resolution on response is studied in three Districts of Rotterdam (NL): Kralingen, Spaanse Polder and Centrum district. These catchments have different average drainage area size (from 2km2 to 7km2), and different general characteristics. Centrum district and Kralingen are, indeed, more various and include residential and commercial areas, big green areas and a small industrial area, while Spaanse Polder is a industrial area, densely urbanized, and presents a high percentage of imperviousness.
Zhuang, Leimeng; Zhu, Chen; Corcoran, Bill; Burla, Maurizio; Roeloffzen, Chris G H; Leinse, Arne; Schröder, Jochen; Lowery, Arthur J
2016-03-21
Modern optical communications rely on high-resolution, high-bandwidth filtering to maximize the data-carrying capacity of fiber-optic networks. Such filtering typically requires high-speed, power-hungry digital processes in the electrical domain. Passive optical filters currently provide high bandwidths with low power consumption, but at the expense of resolution. Here, we present a passive filter chip that functions as an optical Nyquist-filtering interleaver featuring sub-GHz resolution and a near-rectangular passband with 8% roll-off. This performance is highly promising for high-spectral-efficiency Nyquist wavelength division multiplexed (N-WDM) optical super-channels. The chip provides a simple two-ring-resonator-assisted Mach-Zehnder interferometer, which has a sub-cm2 footprint owing to the high-index-contrast Si3N4/SiO2 waveguide, while manifests low wavelength-dependency enabling C-band (> 4 THz) coverage with more than 160 effective free spectral ranges of 25 GHz. This device is anticipated to be a critical building block for spectrally-efficient, chip-scale transceivers and ROADMs for N-WDM super-channels in next-generation optical communication networks.
X-ray structure determination at low resolution
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brunger, Axel T., E-mail: brunger@stanford.edu; Department of Molecular and Cellular Physiology, Stanford University; Department of Neurology and Neurological Sciences, Stanford University
2009-02-01
Refinement is meaningful even at 4 Å or lower, but with present methodologies it should start from high-resolution crystal structures whenever possible. As an example of structure determination in the 3.5–4.5 Å resolution range, crystal structures of the ATPase p97/VCP, consisting of an N-terminal domain followed by a tandem pair of ATPase domains (D1 and D2), are discussed. The structures were originally solved by molecular replacement with the high-resolution structure of the N-D1 fragment of p97/VCP, whereas the D2 domain was manually built using its homology to the D1 domain as a guide. The structure of the D2 domain alonemore » was subsequently solved at 3 Å resolution. The refined model of D2 and the high-resolution structure of the N-D1 fragment were then used as starting models for re-refinement against the low-resolution diffraction data for full-length p97. The re-refined full-length models showed significant improvement in both secondary structure and R values. The free R values dropped by as much as 5% compared with the original structure refinements, indicating that refinement is meaningful at low resolution and that there is information in the diffraction data even at ∼4 Å resolution that objectively assesses the quality of the model. It is concluded that de novo model building is problematic at low resolution and refinement should start from high-resolution crystal structures whenever possible.« less
NASA Astrophysics Data System (ADS)
Yilmaz, Hasan
2016-03-01
Structured illumination enables high-resolution fluorescence imaging of nanostructures [1]. We demonstrate a new high-resolution fluorescence imaging method that uses a scattering layer with a high-index substrate as a solid immersion lens [2]. Random scattering of coherent light enables a speckle pattern with a very fine structure that illuminates the fluorescent nanospheres on the back surface of the high-index substrate. The speckle pattern is raster-scanned over the fluorescent nanospheres using a speckle correlation effect known as the optical memory effect. A series of standard-resolution fluorescence images per each speckle pattern displacement are recorded by an electron-multiplying CCD camera using a commercial microscope objective. We have developed a new phase-retrieval algorithm to reconstruct a high-resolution, wide-field image from several standard-resolution wide-field images. We have introduced phase information of Fourier components of standard-resolution images as a new constraint in our algorithm which discards ambiguities therefore ensures convergence to a unique solution. We demonstrate two-dimensional fluorescence images of a collection of nanospheres with a deconvolved Abbe resolution of 116 nm and a field of view of 10 µm × 10 µm. Our method is robust against optical aberrations and stage drifts, therefore excellent for imaging nanostructures under ambient conditions. [1] M. G. L. Gustafsson, J. Microsc. 198, 82-87 (2000). [2] H. Yilmaz, E. G. van Putten, J. Bertolotti, A. Lagendijk, W. L. Vos, and A. P. Mosk, Optica 2, 424-429 (2015).
NASA Astrophysics Data System (ADS)
Scaduto, David A.; Lubinsky, Anthony R.; Rowlands, John A.; Kenmotsu, Hidenori; Nishimoto, Norihito; Nishino, Takeshi; Tanioka, Kenkichi; Zhao, Wei
2014-03-01
We have previously proposed SAPHIRE (scintillator avalanche photoconductor with high resolution emitter readout), a novel detector concept with potentially superior spatial resolution and low-dose performance compared with existing flat-panel imagers. The detector comprises a scintillator that is optically coupled to an amorphous selenium photoconductor operated with avalanche gain, known as high-gain avalanche rushing photoconductor (HARP). High resolution electron beam readout is achieved using a field emitter array (FEA). This combination of avalanche gain, allowing for very low-dose imaging, and electron emitter readout, providing high spatial resolution, offers potentially superior image quality compared with existing flat-panel imagers, with specific applications to fluoroscopy and breast imaging. Through the present collaboration, a prototype HARP sensor with integrated electrostatic focusing and nano- Spindt FEA readout technology has been fabricated. The integrated electron-optic focusing approach is more suitable for fabricating large-area detectors. We investigate the dependence of spatial resolution on sensor structure and operating conditions, and compare the performance of electrostatic focusing with previous technologies. Our results show a clear dependence of spatial resolution on electrostatic focusing potential, with performance approaching that of the previous design with external mesh-electrode. Further, temporal performance (lag) of the detector is evaluated and the results show that the integrated electrostatic focusing design exhibits comparable or better performance compared with the mesh-electrode design. This study represents the first technical evaluation and characterization of the SAPHIRE concept with integrated electrostatic focusing.
DMI's Baltic Sea Coastal operational forecasting system
NASA Astrophysics Data System (ADS)
Murawski, Jens; Berg, Per; Weismann Poulsen, Jacob
2017-04-01
Operational forecasting is challenged with bridging the gap between the large scales of the driving weather systems and the local, human scales of the model applications. The limit of what can be represented by local model has been continuously shifted to higher and higher spatial resolution, with the aim to better resolve the local dynamic and to make it possible to describe processes that could only be parameterised in older versions, with the ultimate goal to improve the quality of the forecast. Current hardware trends demand a str onger focus on the development of efficient, highly parallelised software and require a refactoring of the code with a solid focus on portable performance. The gained performance can be used for running high resolution model with a larger coverage. Together with the development of efficient two-way nesting routines, this has made it possible to approach the near-coastal zone with model applications that can run in a time effective way. Denmarks Meteorological Institute uses the HBM(1) ocean circulation model for applications that covers the entire Baltic Sea and North Sea with an integrated model set-up that spans the range of horizontal resolution from 1nm for the entire Baltic Sea to approx. 200m resolution in local fjords (Limfjord). For the next model generation, the high resolution set-ups are going to be extended and new high resolution domains in coastal zones are either implemented or tested for operational use. For the first time it will be possible to cover large stretches of the Baltic coastal zone with sufficiently high resolution to model the local hydrodynamic adequately. (1) HBM stands for HIROMB-BOOS-Model, whereas HIROMB stands for "High Resolution Model for the Baltic Sea" and BOOS stands for "Baltic Operational Oceanography System".
Remote sensing in support of high-resolution terrestrial carbon monitoring and modeling
NASA Astrophysics Data System (ADS)
Hurtt, G. C.; Zhao, M.; Dubayah, R.; Huang, C.; Swatantran, A.; ONeil-Dunne, J.; Johnson, K. D.; Birdsey, R.; Fisk, J.; Flanagan, S.; Sahajpal, R.; Huang, W.; Tang, H.; Armstrong, A. H.
2014-12-01
As part of its Phase 1 Carbon Monitoring System (CMS) activities, NASA initiated a Local-Scale Biomass Pilot study. The goals of the pilot study were to develop protocols for fusing high-resolution remotely sensed observations with field data, provide accurate validation test areas for the continental-scale biomass product, and demonstrate efficacy for prognostic terrestrial ecosystem modeling. In Phase 2, this effort was expanded to the state scale. Here, we present results of this activity focusing on the use of remote sensing in high-resolution ecosystem modeling. The Ecosystem Demography (ED) model was implemented at 90 m spatial resolution for the entire state of Maryland. We rasterized soil depth and soil texture data from SSURGO. For hourly meteorological data, we spatially interpolated 32-km 3-hourly NARR into 1-km hourly and further corrected them at monthly level using PRISM data. NLCD data were used to mask sand, seashore, and wetland. High-resolution 1 m forest/non-forest mapping was used to define forest fraction of 90 m cells. Three alternative strategies were evaluated for initialization of forest structure using high-resolution lidar, and the model was used to calculate statewide estimates of forest biomass, carbon sequestration potential, time to reach sequestration potential, and sensitivity to future forest growth and disturbance rates, all at 90 m resolution. To our knowledge, no dynamic ecosystem model has been run at such high spatial resolution over such large areas utilizing remote sensing and validated as extensively. There are over 3 million 90 m land cells in Maryland, greater than 43 times the ~73,000 half-degree cells in a state-of-the-art global land model.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li Dan; Zhao Wei
2008-07-15
An indirect flat panel imager (FPI) with programmable avalanche gain and field emitter array (FEA) readout is being investigated for low-dose and high resolution x-ray imaging. It is made by optically coupling a structured x-ray scintillator, e.g., thallium (Tl) doped cesium iodide (CsI), to an amorphous selenium (a-Se) avalanche photoconductor called high-gain avalanche rushing amorphous photoconductor (HARP). The charge image created by the scintillator/HARP (SHARP) combination is read out by the electron beams emitted from the FEA. The proposed detector is called scintillator avalanche photoconductor with high resolution emitter readout (SAPHIRE). The programmable avalanche gain of HARP can improve themore » low dose performance of indirect FPI while the FEA can be made with pixel sizes down to 50 {mu}m. Because of the avalanche gain, a high resolution type of CsI (Tl), which has not been widely used in indirect FPI due to its lower light output, can be used to improve the high spatial frequency performance. The purpose of the present article is to investigate the factors affecting the spatial resolution of SAPHIRE. Since the resolution performance of the SHARP combination has been well studied, the focus of the present work is on the inherent resolution of the FEA readout method. The lateral spread of the electron beam emitted from a 50 {mu}mx50 {mu}m pixel FEA was investigated with two different electron-optical designs: mesh-electrode-only and electrostatic focusing. Our results showed that electrostatic focusing can limit the lateral spread of electron beams to within the pixel size of down to 50 {mu}m. Since electrostatic focusing is essentially independent of signal intensity, it will provide excellent spatial uniformity.« less
NASA Astrophysics Data System (ADS)
Descloux, A.; Grußmayer, K. S.; Bostan, E.; Lukes, T.; Bouwens, A.; Sharipov, A.; Geissbuehler, S.; Mahul-Mellier, A.-L.; Lashuel, H. A.; Leutenegger, M.; Lasser, T.
2018-03-01
Super-resolution fluorescence microscopy provides unprecedented insight into cellular and subcellular structures. However, going `beyond the diffraction barrier' comes at a price, since most far-field super-resolution imaging techniques trade temporal for spatial super-resolution. We propose the combination of a novel label-free white light quantitative phase imaging with fluorescence to provide high-speed imaging and spatial super-resolution. The non-iterative phase retrieval relies on the acquisition of single images at each z-location and thus enables straightforward 3D phase imaging using a classical microscope. We realized multi-plane imaging using a customized prism for the simultaneous acquisition of eight planes. This allowed us to not only image live cells in 3D at up to 200 Hz, but also to integrate fluorescence super-resolution optical fluctuation imaging within the same optical instrument. The 4D microscope platform unifies the sensitivity and high temporal resolution of phase imaging with the specificity and high spatial resolution of fluorescence microscopy.
NASA Astrophysics Data System (ADS)
Boon, Choong S.; Guleryuz, Onur G.; Kawahara, Toshiro; Suzuki, Yoshinori
2006-08-01
We consider the mobile service scenario where video programming is broadcast to low-resolution wireless terminals. In such a scenario, broadcasters utilize simultaneous data services and bi-directional communications capabilities of the terminals in order to offer substantially enriched viewing experiences to users by allowing user participation and user tuned content. While users immediately benefit from this service when using their phones in mobile environments, the service is less appealing in stationary environments where a regular television provides competing programming at much higher display resolutions. We propose a fast super-resolution technique that allows the mobile terminals to show a much enhanced version of the broadcast video on nearby high-resolution devices, extending the appeal and usefulness of the broadcast service. The proposed single frame super-resolution algorithm uses recent sparse recovery results to provide high quality and high-resolution video reconstructions based solely on individual decoded frames provided by the low-resolution broadcast.
Widmann, K.; Beiersdorfer, P.; Magee, E. W.; ...
2014-09-19
In this paper, we have constructed a high-resolution grazing-incidence spectrometer designed for measuring the ion temperature of low-Z elements, such as Li + or Li 2 +, which radiate near 199 Å and 135 Å, respectively. Based on measurements at the Livermore Electron Beam Ion Trap we have shown that the instrumental resolution is better than 48 mÅ at the 200 Å setting and better than 40 mÅ for the 135-Å range. Such a high spectral resolution corresponds to an instrumental limit for line-width based temperature measurements of about 45 eV for the 199 Å Li+ and 65 eV formore » the 135 Å Li 2 + lines. Finally, recently obtained survey spectra from the Lithium Tokamak Experiment at the Princeton Plasma Physics Laboratory show the presence of these lithium emission lines and the expected core ion temperature of approximately 70 eV is sufficiently high to demonstrate the feasibility of utilizing our high-resolution spectrometer as an ion-temperature diagnostic.« less
Graphene-enabled electron microscopy and correlated super-resolution microscopy of wet cells.
Wojcik, Michal; Hauser, Margaret; Li, Wan; Moon, Seonah; Xu, Ke
2015-06-11
The application of electron microscopy to hydrated biological samples has been limited by high-vacuum operating conditions. Traditional methods utilize harsh and laborious sample dehydration procedures, often leading to structural artefacts and creating difficulties for correlating results with high-resolution fluorescence microscopy. Here, we utilize graphene, a single-atom-thick carbon meshwork, as the thinnest possible impermeable and conductive membrane to protect animal cells from vacuum, thus enabling high-resolution electron microscopy of wet and untreated whole cells with exceptional ease. Our approach further allows for facile correlative super-resolution and electron microscopy of wet cells directly on the culturing substrate. In particular, individual cytoskeletal actin filaments are resolved in hydrated samples through electron microscopy and well correlated with super-resolution results.
Sub-micron resolution selected area electron channeling patterns.
Guyon, J; Mansour, H; Gey, N; Crimp, M A; Chalal, S; Maloufi, N
2015-02-01
Collection of selected area channeling patterns (SACPs) on a high resolution FEG-SEM is essential to carry out quantitative electron channeling contrast imaging (ECCI) studies, as it facilitates accurate determination of the crystal plane normal with respect to the incident beam direction and thus allows control the electron channeling conditions. Unfortunately commercial SACP modes developed in the past were limited in spatial resolution and are often no longer offered. In this contribution we present a novel approach for collecting high resolution SACPs (HR-SACPs) developed on a Gemini column. This HR-SACP technique combines the first demonstrated sub-micron spatial resolution with high angular accuracy of about 0.1°, at a convenient working distance of 10mm. This innovative approach integrates the use of aperture alignment coils to rock the beam with a digitally calibrated beam shift procedure to ensure the rocking beam is maintained on a point of interest. Moreover a new methodology to accurately measure SACP spatial resolution is proposed. While column considerations limit the rocking angle to 4°, this range is adequate to index the HR-SACP in conjunction with the pattern simulated from the approximate orientation deduced by EBSD. This new technique facilitates Accurate ECCI (A-ECCI) studies from very fine grained and/or highly strained materials. It offers also new insights for developing HR-SACP modes on new generation high-resolution electron columns. Copyright © 2014 Elsevier B.V. All rights reserved.
High-resolution compact shear stress sensor for direct measurement of skin friction in fluid flow
NASA Astrophysics Data System (ADS)
Xu, Muchen; Kim, Chang-Jin ``Cj''
2015-11-01
The high-resolution measurement of skin friction in complex flows has long been of great interest but also a challenge in fluid mechanics. Compared with indirect measurement methods (e.g., laser Doppler velocimetry), direct measurement methods (e.g., floating element) do not involve any analogy and assumption but tend to suffer from instrumentation challenges, such as low sensing resolution or misalignments. Recently, silicon micromachined floating plates showed good resolution and perfect alignment but were too small for general purposes and too fragile to attach other surface samples repeatedly. In this work, we report a skin friction sensor consisting of a monolithic floating plate and a high-resolution optical encoder to measure its displacement. The key for the high resolution is in the suspension beams, which are very narrow (e.g., 0.25 mm) to sense small frictions along the flow direction but thick (e.g., 5 mm) to be robust along all other directions. This compact, low profile, and complete sensor is easy to use and allows repeated attachment and detachment of surface samples. The sheer-stress sensor has been tested in water tunnel and towing tank at different flow conditions, showing high sensing resolution for skin friction measurement. Supported by National Science Foundation (NSF) (No. 1336966) and Defense Advanced Research Projects Agency (DARPA) (No. HR0011-15-2-0021).
Monitoring Termite-Mediated Ecosystem Processes Using Moderate and High Resolution Satellite Imagery
NASA Astrophysics Data System (ADS)
Lind, B. M.; Hanan, N. P.
2016-12-01
Termites are considered dominant decomposers and prominent ecosystem engineers in the global tropics and they build some of the largest and architecturally most complex non-human-made structures in the world. Termite mounds significantly alter soil texture, structure, and nutrients, and have major implications for local hydrological dynamics, vegetation characteristics, and biological diversity. An understanding of how these processes change across large scales has been limited by our ability to detect termite mounds at high spatial resolutions. Our research develops methods to detect large termite mounds in savannas across extensive geographic areas using moderate and high resolution satellite imagery. We also investigate the effect of termite mounds on vegetation productivity using Landsat-8 maximum composite NDVI data as a proxy for production. Large termite mounds in arid and semi-arid Senegal generate highly reflective `mound scars' with diameters ranging from 10 m at minimum to greater than 30 m. As Sentinel-2 has several bands with 10 m resolution and Landsat-8 has improved calibration, higher radiometric resolution, 15 m spatial resolution (pansharpened), and improved contrast between vegetated and bare surfaces compared to previous Landsat missions, we found that the largest and most influential mounds in the landscape can be detected. Because mounds as small as 4 m in diameter are easily detected in high resolution imagery we used these data to validate detection results and quantify omission errors for smaller mounds.
High-resolution streaming video integrated with UGS systems
NASA Astrophysics Data System (ADS)
Rohrer, Matthew
2010-04-01
Imagery has proven to be a valuable complement to Unattended Ground Sensor (UGS) systems. It provides ultimate verification of the nature of detected targets. However, due to the power, bandwidth, and technological limitations inherent to UGS, sacrifices have been made to the imagery portion of such systems. The result is that these systems produce lower resolution images in small quantities. Currently, a high resolution, wireless imaging system is being developed to bring megapixel, streaming video to remote locations to operate in concert with UGS. This paper will provide an overview of how using Wifi radios, new image based Digital Signal Processors (DSP) running advanced target detection algorithms, and high resolution cameras gives the user an opportunity to take high-powered video imagers to areas where power conservation is a necessity.
Song, Jung-Hwan; Lee, Kee-Woong; Lee, Woo-Kyung; Jung, Chul-Ho
2017-01-01
A high resolution inverse synthetic aperture radar (ISAR) technique is presented using modified Doppler history based motion compensation. To this purpose, a novel wideband ISAR system is developed that accommodates parametric processing over extended aperture length. The proposed method is derived from an ISAR-to-SAR approach that makes use of high resolution spotlight SAR and sub-aperture recombination. It is dedicated to wide aperture ISAR imaging and exhibits robust performance against unstable targets having non-linear motions. We demonstrate that the Doppler histories of the full aperture ISAR echoes from disturbed targets are efficiently retrieved with good fitting models. Experiments have been conducted on real aircraft targets and the feasibility of the full aperture ISAR processing is verified through the acquisition of high resolution ISAR imagery. PMID:28555036
Fusing Unmanned Aerial Vehicle Imagery with High Resolution Hydrologic Modeling (Invited)
NASA Astrophysics Data System (ADS)
Vivoni, E. R.; Pierini, N.; Schreiner-McGraw, A.; Anderson, C.; Saripalli, S.; Rango, A.
2013-12-01
After decades of development and applications, high resolution hydrologic models are now common tools in research and increasingly used in practice. More recently, high resolution imagery from unmanned aerial vehicles (UAVs) that provide information on land surface properties have become available for civilian applications. Fusing the two approaches promises to significantly advance the state-of-the-art in terms of hydrologic modeling capabilities. This combination will also challenge assumptions on model processes, parameterizations and scale as land surface characteristics (~0.1 to 1 m) may now surpass traditional model resolutions (~10 to 100 m). Ultimately, predictions from high resolution hydrologic models need to be consistent with the observational data that can be collected from UAVs. This talk will describe our efforts to develop, utilize and test the impact of UAV-derived topographic and vegetation fields on the simulation of two small watersheds in the Sonoran and Chihuahuan Deserts at the Santa Rita Experimental Range (Green Valley, AZ) and the Jornada Experimental Range (Las Cruces, NM). High resolution digital terrain models, image orthomosaics and vegetation species classification were obtained from a fixed wing airplane and a rotary wing helicopter, and compared to coarser analyses and products, including Light Detection and Ranging (LiDAR). We focus the discussion on the relative improvements achieved with UAV-derived fields in terms of terrain-hydrologic-vegetation analyses and summer season simulations using the TIN-based Real-time Integrated Basin Simulator (tRIBS) model. Model simulations are evaluated at each site with respect to a high-resolution sensor network consisting of six rain gauges, forty soil moisture and temperature profiles, four channel runoff flumes, a cosmic-ray soil moisture sensor and an eddy covariance tower over multiple summer periods. We also discuss prospects for the fusion of high resolution models with novel observations from UAVs, including synthetic aperture radar and multispectral imagery.
ERIC Educational Resources Information Center
Pacilio, Julia E.; Tokarski, John T.; Quiñones, Rosalynn; Iuliucci, Robbie J.
2014-01-01
High-resolution solid-state NMR (SSNMR) spectroscopy has many advantages as a tool to characterize solid-phase material that finds applications in polymer chemistry, nanotechnology, materials science, biomolecular structure determination, and others, including the pharmaceutical industry. The technology associated with achieving high resolution…
A set of high-quality, age-specific biota-sediment accumulation factors (BSAFs) for polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), and dibenzofurans (PCDFs) have been determined from concentrations measured with high-resolution gas chroma tography/high-resolution ma...
High resolution ceramic gun for projection CRT
NASA Astrophysics Data System (ADS)
Muchi, T.; Tagami, S.; Saito, T.
1995-08-01
A ceramic resistor with high-resistivity and a low thermal coefficient has been developed. The use of this ceramic material as a cylindrical electrode realizes an electrostatic lens with low spherical aberration. A ceramic electron gun based on a new concept has been developed for high resolution projection CRTs.
A Dedicated Micro-Tomography Beamline For The Australian Synchrotron
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mayo, Sheridan C.; Stevenson, Andrew W.; Wilkins, Stephen W.
2010-07-23
A dedicated micro-tomography beamline is proposed for the Australian Synchrotron. It will enable high-resolution micro-tomography with resolution below a micron and supporting phase-contrast imaging modes. A key feature of the beamline will be high-throughput/high-speed operation enabling near real-time micro-tomography.
Ko, Guen Bae; Lee, Jae Sung
2015-01-01
Metal package photomultiplier tubes (PMTs) with a metal channel dynode structure have several advanced features for devising such time-of-flight (TOF) and high spatial resolution positron emission tomography (PET) detectors, thanks to their high packing density, large effective area ratio, fast time response, and position encoding capability. Here, we report on an investigation of new metal package PMTs with high quantum efficiency (QE) for high-resolution PET and TOF PET detector modules. The latest metal package PMT, the Hamamatsu R11265 series, is served with two kinds of photocathodes that have higher quantum efficiency than normal bialkali (typical QE ≈ 25%), super bialkali (SBA; QE ≈ 35%), and ultra bialkali (UBA; QE ≈ 43%). In this study, the authors evaluated the performance of the new PMTs with SBA and UBA photocathodes as a PET detector by coupling various crystal arrays. They also investigated the performance improvements of high QE, focusing in particular on a block detector coupled with a lutetium-based scintillator. A single 4 × 4 × 10 mm(3) LYSO, a 7 × 7 array of 3 × 3 × 20 mm(3) LGSO, a 9 × 9 array of 1.2 × 1.2 × 10 mm(3) LYSO, and a 6 × 6 array of 1.5 × 1.5 × 7 mm(3) LuYAP were used for evaluation. All coincidence data were acquired with a DRS4 based fast digitizer. This new PMT shows promising crystal positioning accuracy, energy and time discrimination performance for TOF, and high-resolution PET applications. The authors also found that a metal channel PMT with SBA was enough for both TOF and high-resolution application, although UBA gave a minor improvement to time resolution. However, significant performance improvement was observed in relative low light output crystals (LuYAP) coupled with UBA. The results of this study will be of value as a useful reference to select PMTs for high-performance PET detectors.
MSE spectrograph optical design: a novel pupil slicing technique
NASA Astrophysics Data System (ADS)
Spanò, P.
2014-07-01
The Maunakea Spectroscopic Explorer shall be mainly devoted to perform deep, wide-field, spectroscopic surveys at spectral resolutions from ~2000 to ~20000, at visible and near-infrared wavelengths. Simultaneous spectral coverage at low resolution is required, while at high resolution only selected windows can be covered. Moreover, very high multiplexing (3200 objects) must be obtained at low resolution. At higher resolutions a decreased number of objects (~800) can be observed. To meet such high demanding requirements, a fiber-fed multi-object spectrograph concept has been designed by pupil-slicing the collimated beam, followed by multiple dispersive and camera optics. Different resolution modes are obtained by introducing anamorphic lenslets in front of the fiber arrays. The spectrograph is able to switch between three resolution modes (2000, 6500, 20000) by removing the anamorphic lenses and exchanging gratings. Camera lenses are fixed in place to increase stability. To enhance throughput, VPH first-order gratings has been preferred over echelle gratings. Moreover, throughput is kept high over all wavelength ranges by splitting light into more arms by dichroic beamsplitters and optimizing efficiency for each channel by proper selection of glass materials, coatings, and grating parameters.
NASA Astrophysics Data System (ADS)
Welle, Paul D.; Mauter, Meagan S.
2017-09-01
This work introduces a generalizable approach for estimating the field-scale agricultural yield losses due to soil salinization. When integrated with regional data on crop yields and prices, this model provides high-resolution estimates for revenue losses over large agricultural regions. These methods account for the uncertainty inherent in model inputs derived from satellites, experimental field data, and interpreted model results. We apply this method to estimate the effect of soil salinity on agricultural outputs in California, performing the analysis with both high-resolution (i.e. field scale) and low-resolution (i.e. county-scale) data sources to highlight the importance of spatial resolution in agricultural analysis. We estimate that soil salinity reduced agricultural revenues by 3.7 billion (1.7-7.0 billion) in 2014, amounting to 8.0 million tons of lost production relative to soil salinities below the crop-specific thresholds. When using low-resolution data sources, we find that the costs of salinization are underestimated by a factor of three. These results highlight the need for high-resolution data in agro-environmental assessment as well as the challenges associated with their integration.
Submicron-resolution photoacoustic microscopy of endogenous light-absorbing biomolecules
NASA Astrophysics Data System (ADS)
Zhang, Chi
Photoacoustic imaging in biomedicine has the unique advantage of probing endogenous light absorbers at various length scales with a 100% relative sensitivity. Among the several modalities of photoacoustic imaging, optical-resolution photoacoustic microscopy (OR-PAM) can achieve high spatial resolution, on the order of optical wavelength, at <1 mm depth in biological tissue (the optical ballistic regime). OR-PAM has been applied successfully to structural and functional imaging of blood vasculature and red blood cells in vivo. Any molecules which absorb sufficient light at certain wavelengths can potentially be imaged by PAM. Compared with pure optical imaging, which typically targets fluorescent markers, label-free PAM avoids the major concerns that the fluorescent labeling probes may disturb the function of biomolecules and may have an insufficient density. This dissertation aims to advance label-free OR-PAM to the subcellular scale. The first part of this dissertation describes the technological advancement of PAM yielding high spatial resolution in 3D. The lateral resolution was improved by using optical objectives with high numerical apertures for optical focusing. The axial resolution was improved by using broadband ultrasonic transducers for ultrasound detection. We achieved 220 nm lateral resolution in transmission mode, 0.43 microm lateral resolution in reflection mode, 7.6 microm axial resolution in normal tissue, and 5.8 microm axial resolution with silicone oil immersion/injection. The achieved lateral resolution and axial resolution were the finest reported at the time. With high-resolution in 3D, PAM was demonstrated to resolve cellular and subcellular structures in vivo, such as red blood cells and melanosomes in melanoma cells. Compared with previous PAM systems, our high-resolution PAM could resolve capillaries in mouse ears more clearly. As an example application, we demonstrated intracellular temperature imaging, assisted by fluorescence signal detection, with sub-degree temperature resolution and sub-micron lateral resolution. The second part of this dissertation describes the exploration of endogenous light-absorbing biomolecules for PAM. We demonstrated cytochromes and myoglobin as new absorption contrasts for PAM and identified the corresponding optimal wavelengths for imaging. Fixed fibroblasts on slides and mouse ear sections were imaged by PAM at 422 nm and 250 nm wavelengths to reveal cytoplasms and nuclei, respectively, as confirmed by standard hematoxylin and eosin (H&E) histology. By imaging a blood-perfused mouse heart at 532 nm down to 150 microm in depth, we derived the myocardial sheet thickness and the cleavage height from an undehydrated heart for the first time. The findings promote PAM at new wavelengths and open up new possibilities for characterizing biological tissue. Of particular interest, dual-wavelength PAM around 250 nm and 420 nm wavelengths is analogous to H&E histology. The last part of this dissertation describes the development of sectioning photoacoustic microscopy (SPAM), based on the advancement in spatial resolution and new contrasts for PAM, with applications in brain histology. Label-free SPAM, assisted by a microtome, acquires serial distortion-free images of a specimen on the surface. By exciting cell nuclei at 266 nm wavelength with high resolution, SPAM could pinpoint cell nuclei sensitively and specifically in the mouse brain section, as confirmed by H&E histology. SPAM was demonstrated to generate high-resolution 3D images, highlighting cell nuclei, of formalin-fixed paraffin-embedded mouse brains without tissue staining or clearing. SPAM can potentially serve as a high-throughput and minimal-artifact substitute for histology, probe many other biomolecules and cells, and become a universal tool for animal or human whole-organ microscopy, with diverse applications in life sciences.
2017-01-26
Naval Research Laboratory Washington, DC 20375-5320 NRL/MR/5514--17-9692 High Resolution Bathymetry Estimation Improvement with Single Image Super...collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources...gathering and maintaining the data needed, and completing and reviewing this collection of information. Send comments regarding this burden estimate
Spread-Spectrum Beamforming and Clutter Filtering for Plane-Wave Color Doppler Imaging.
Mansour, Omar; Poepping, Tamie L; Lacefield, James C
2016-07-21
Plane-wave imaging is desirable for its ability to achieve high frame rates, allowing the capture of fast dynamic events and continuous Doppler data. In most implementations of plane-wave imaging, multiple low-resolution images from different plane wave tilt angles are compounded to form a single high-resolution image, thereby reducing the frame rate. Compounding improves the lateral beam profile in the high-resolution image, but it also acts as a low-pass filter in slow time that causes attenuation and aliasing of signals with high Doppler shifts. This paper introduces a spread-spectrum color Doppler imaging method that produces high-resolution images without the use of compounding, thereby eliminating the tradeoff between beam quality, maximum unaliased Doppler frequency, and frame rate. The method uses a long, random sequence of transmit angles rather than a linear sweep of plane wave directions. The random angle sequence randomizes the phase of off-focus (clutter) signals, thereby spreading the clutter power in the Doppler spectrum, while keeping the spectrum of the in-focus signal intact. The ensemble of randomly tilted low-resolution frames also acts as the Doppler ensemble, so it can be much longer than a conventional linear sweep, thereby improving beam formation while also making the slow-time Doppler sampling frequency equal to the pulse repetition frequency. Experiments performed using a carotid artery phantom with constant flow demonstrate that the spread-spectrum method more accurately measures the parabolic flow profile of the vessel and outperforms conventional plane-wave Doppler in both contrast resolution and estimation of high flow velocities. The spread-spectrum method is expected to be valuable for Doppler applications that require measurement of high velocities at high frame rates.
Mesoscale landscape model of gypsy moth phenology
Joseph M. Russo; John G. W. Kelley; Andrew M. Liebhold
1991-01-01
A recently-developed high resolution climatological temperature data base was input into a gypsy moth phenology model. The high resolution data were created from a coupling of 30-year averages of station observations and digital elevation data. The resultant maximum and minimum temperatures have about a 1 km resolution which represents meteorologically the mesoscale....
A key factor for improving models of ecosystem benefits is the availability of high quality spatial data. High resolution LIDAR data are now commonly available and can be used to produce more accurate model outputs. However, increased resolution leads to higher computer resource...
Reproducible high-resolution multispectral image acquisition in dermatology
NASA Astrophysics Data System (ADS)
Duliu, Alexandru; Gardiazabal, José; Lasser, Tobias; Navab, Nassir
2015-07-01
Multispectral image acquisitions are increasingly popular in dermatology, due to their improved spectral resolution which enables better tissue discrimination. Most applications however focus on restricted regions of interest, imaging only small lesions. In this work we present and discuss an imaging framework for high-resolution multispectral imaging on large regions of interest.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Swartz, J.D.; Goodman, R.S.; Russell, K.B.
1983-08-01
High-resolution computed tomography (CT) provides an excellent method for examination of the surgically altered middle ear and mastoid. Closed-cavity and open-cavity types of mastoidectomy are illustrated. Recurrent cholesteatoma in the mastoid bowl is easily diagnosed. Different types of tympanoplasty are discussed and illustrated, as are tympanostomy tubes and various ossicular reconstructive procedures. Baseline high-resolution CT of the postoperative middle ear and mastoid is recommended at approximately 3 months following the surgical procedure.
High Resolution Higher Energy X-ray Microscope for Mesoscopic Materials
NASA Astrophysics Data System (ADS)
Snigireva, I.; Snigirev, A.
2013-10-01
We developed a novel X-ray microscopy technique to study mesoscopically structured materials, employing compound refractive lenses. The easily seen advantage of lens-based methodology is the possibility to retrieve high resolution diffraction pattern and real-space images in the same experimental setup. Methodologically the proposed approach is similar to the studies of crystals by high resolution transmission electron microscopy. The proposed microscope was applied for studying of mesoscopic materials such as natural and synthetic opals, inverted photonic crystals.
NASA Astrophysics Data System (ADS)
Takei, Satoshi; Hanabata, Makoto
2017-03-01
We report high-resolution (150 nm) nanopatterning of biodegradable polylactide by thermal nanoimprint lithography using dichloromethane as a volatile solvent for improving the liquidity and a porous cyclodextrin-based gas-permeable mold. This study demonstrates the high-resolution patterning of polylactic acid and other non-liquid functional materials with poor fluidity by thermal nanoimprinting. Such a patterning is expected to expand the utility of thermal nanoimprint lithography and fabricate non-liquid functional materials suitable for eco-friendly and biomedical applications.
Super resolution reconstruction of μ-CT image of rock sample using neighbour embedding algorithm
NASA Astrophysics Data System (ADS)
Wang, Yuzhu; Rahman, Sheik S.; Arns, Christoph H.
2018-03-01
X-ray computed tomography (μ-CT) is considered to be the most effective way to obtain the inner structure of rock sample without destructions. However, its limited resolution hampers its ability to probe sub-micro structures which is critical for flow transportation of rock sample. In this study, we propose an innovative methodology to improve the resolution of μ-CT image using neighbour embedding algorithm where low frequency information is provided by μ-CT image itself while high frequency information is supplemented by high resolution scanning electron microscopy (SEM) image. In order to obtain prior for reconstruction, a large number of image patch pairs contain high- and low- image patches are extracted from the Gaussian image pyramid generated by SEM image. These image patch pairs contain abundant information about tomographic evolution of local porous structures under different resolution spaces. Relying on the assumption of self-similarity of porous structure, this prior information can be used to supervise the reconstruction of high resolution μ-CT image effectively. The experimental results show that the proposed method is able to achieve the state-of-the-art performance.
Calibration of Fuji BAS-SR type imaging plate as high spatial resolution x-ray radiography recorder
NASA Astrophysics Data System (ADS)
Yan, Ji; Zheng, Jianhua; Zhang, Xing; Chen, Li; Wei, Minxi
2017-05-01
Image Plates as x-ray recorder have advantages including reusable, high dynamic range, large active area, and so on. In this work, Fuji BAS-SR type image plate combined with BAS-5000 scanner is calibrated. The fade rates of Image Plates has been measured using x-ray diffractometric in different room temperature; the spectral response of Image Plates has been measured using 241Am radioactive sealed source and fitting with linear model; the spatial resolution of Image Plates has been measured using micro-focus x-ray tube. The results show that Image Plates has an exponent decade curve and double absorption edge response curve. The spatial resolution of Image Plates with 25μ/50μ scanner resolution is 6.5lp/mm, 11.9lp/mm respectively and gold grid radiography is collected with 80lp/mm spatial resolution using SR-type Image Plates. BAS-SR type Image Plates can do high spatial resolution and quantitative radiographic works. It can be widely used in High energy density physics (HEDP), inertial confinement fusion (ICF) and laboratory astronomy physics.
High-resolution Bent-crystal Spectrometer for the Ultra-soft X-ray Region
DOE R&D Accomplishments Database
Beiersdorfer, P.; von Goeler, S.; Bitter, M.; Hill, K. W.; Hulse, R. A.; Walling, R. S.
1988-10-01
A multichannel vacuum Brag-crystal spectrometer has been developed for high-resolution measurements of the line emission from tokamak plasmas in the wavelength region between 4 and 25 angstrom. The spectrometer employs a bent crystal in Johann geometry and a microchannel-plate intensified photodiode array. The instrument is capable of measuring high-resolution spectra (lambda/..delta..lambda approx. 3000) with fast time resolution (4 msec per spectrum) and good spatial resolution (3 cm). The spectral bandwidth is ..delta..lambda/lambda{sub 0} = 8 angstrom. A simple tilt mechanism allows access to different wavelength intervals. In order to illustrate the utility of the new spectrometer, time- and space-resolved measurements of the n = 3 to n = 2 spectrum of selenium from the Princeton Large Torus tokamak plasmas are presented. The data are used to determine the plasma transport parameters and to infer the radial distribution of fluorinelike, neonlike, and sodiumlike ions of selenium in the plasma. The new ultra-soft x-ray spectrometer has thus enabled us to demonstrate the utility of high-resolution L-shell spectroscopy of neonlike ions as a fusion diagnostic.
NASA Astrophysics Data System (ADS)
von Storch, Jin-Song
2014-05-01
The German consortium STORM was built to explore high-resolution climate simulations using the high-performance computer stored at the German Climate Computer Center (DKRZ). One of the primary goals is to quantify the effect of unresolved (and parametrized) processes on climate sensitivity. We use ECHAM6/MPIOM, the coupled atmosphere-ocean model developed at the Max-Planck Institute for Meteorology. The resolution is T255L95 for the atmosphere and 1/10 degree and 80 vertical levels for the ocean. We discuss results of stand-alone runs, i.e. the ocean-only simulation driven by the NCEP/NCAR renalaysis and the atmosphere-only AMIP-type of simulation. Increasing resolution leads to a redistribution of biases, even though some improvements, both in the atmosphere and in the ocean, can clearly be attributed to the increase in resolution. We represent also new insights on ocean meso-scale eddies, in particular their effects on the ocean's energetics. Finally, we discuss the status and problems of the coupled high-resolution runs.
Abatzoglou, John T; Dobrowski, Solomon Z; Parks, Sean A; Hegewisch, Katherine C
2018-01-09
We present TerraClimate, a dataset of high-spatial resolution (1/24°, ~4-km) monthly climate and climatic water balance for global terrestrial surfaces from 1958-2015. TerraClimate uses climatically aided interpolation, combining high-spatial resolution climatological normals from the WorldClim dataset, with coarser resolution time varying (i.e., monthly) data from other sources to produce a monthly dataset of precipitation, maximum and minimum temperature, wind speed, vapor pressure, and solar radiation. TerraClimate additionally produces monthly surface water balance datasets using a water balance model that incorporates reference evapotranspiration, precipitation, temperature, and interpolated plant extractable soil water capacity. These data provide important inputs for ecological and hydrological studies at global scales that require high spatial resolution and time varying climate and climatic water balance data. We validated spatiotemporal aspects of TerraClimate using annual temperature, precipitation, and calculated reference evapotranspiration from station data, as well as annual runoff from streamflow gauges. TerraClimate datasets showed noted improvement in overall mean absolute error and increased spatial realism relative to coarser resolution gridded datasets.
NASA Astrophysics Data System (ADS)
Abatzoglou, John T.; Dobrowski, Solomon Z.; Parks, Sean A.; Hegewisch, Katherine C.
2018-01-01
We present TerraClimate, a dataset of high-spatial resolution (1/24°, ~4-km) monthly climate and climatic water balance for global terrestrial surfaces from 1958-2015. TerraClimate uses climatically aided interpolation, combining high-spatial resolution climatological normals from the WorldClim dataset, with coarser resolution time varying (i.e., monthly) data from other sources to produce a monthly dataset of precipitation, maximum and minimum temperature, wind speed, vapor pressure, and solar radiation. TerraClimate additionally produces monthly surface water balance datasets using a water balance model that incorporates reference evapotranspiration, precipitation, temperature, and interpolated plant extractable soil water capacity. These data provide important inputs for ecological and hydrological studies at global scales that require high spatial resolution and time varying climate and climatic water balance data. We validated spatiotemporal aspects of TerraClimate using annual temperature, precipitation, and calculated reference evapotranspiration from station data, as well as annual runoff from streamflow gauges. TerraClimate datasets showed noted improvement in overall mean absolute error and increased spatial realism relative to coarser resolution gridded datasets.
Wang, Sheng; Ding, Miao; Chen, Xuanze; Chang, Lei; Sun, Yujie
2017-01-01
Direct visualization of protein-protein interactions (PPIs) at high spatial and temporal resolution in live cells is crucial for understanding the intricate and dynamic behaviors of signaling protein complexes. Recently, bimolecular fluorescence complementation (BiFC) assays have been combined with super-resolution imaging techniques including PALM and SOFI to visualize PPIs at the nanometer spatial resolution. RESOLFT nanoscopy has been proven as a powerful live-cell super-resolution imaging technique. With regard to the detection and visualization of PPIs in live cells with high temporal and spatial resolution, here we developed a BiFC assay using split rsEGFP2, a highly photostable and reversibly photoswitchable fluorescent protein previously developed for RESOLFT nanoscopy. Combined with parallelized RESOLFT microscopy, we demonstrated the high spatiotemporal resolving capability of a rsEGFP2-based BiFC assay by detecting and visualizing specifically the heterodimerization interactions between Bcl-xL and Bak as well as the dynamics of the complex on mitochondria membrane in live cells. PMID:28663931
Estimation of size of cord blood inventory based on high-resolution typing of HLAs.
Song, E Y; Huh, J Y; Kim, S Y; Kim, T G; Oh, S; Yoon, J H; Roh, E Y; Park, M H; Kang, M S; Shin, S
2014-07-01
Methods for estimating the cord blood (CB) inventory size required vary according to the ethnic diversity of the HLA, degree of HLA matching and HLA-typing resolution. We estimated the CB inventory size required using 7190 stored CB units (CBU) and 2450 patients who were awaiting or underwent allogeneic hematopoietic stem cell transplantation. With high-resolution typing of HLA-A, B and DRB1, 94.6% of Korean patients could find CBUs in 100 000 CBUs with a 5/6 match, and 95.7% could find CBUs in 5000 CBUs with a 4/6 match. With low-resolution typing of HLA-A and B and high-resolution typing of leukocyte antigen-DRB1, 95% of patients could find CBUs in 50 000 CBUs with a 5/6 match, and 96.7% could find CBUs in 3000 CBUs with a 4/6 match. With additional high-resolution typing for HLA-A and B, which could improve transplantation outcome, the size of the CB inventory would need to increase twofold for Koreans.
A Pitch Extraction Method with High Frequency Resolution for Singing Evaluation
NASA Astrophysics Data System (ADS)
Takeuchi, Hideyo; Hoguro, Masahiro; Umezaki, Taizo
This paper proposes a pitch estimation method suitable for singing evaluation incorporable in KARAOKE machines. Professional singers and musicians have sharp hearing for music and singing voice. They recognize that singer's voice pitch is “a little off key” or “be in tune”. In the same way, the pitch estimation method that has high frequency resolution is necessary in order to evaluate singing. This paper proposes a pitch estimation method with high frequency resolution utilizing harmonic characteristic of autocorrelation function. The proposed method can estimate a fundamental frequency in the range 50 ∼ 1700[Hz] with resolution less than 3.6 cents in light processing.
Very high resolution UV and X-ray spectroscopy and imagery of solar active regions
NASA Technical Reports Server (NTRS)
Bruner, M.; Brown, W. A.; Haisch, B. M.
1987-01-01
A scientific investigation of the physics of the solar atmosphere, which uses the techniques of high resolution soft X-ray spectroscopy and high resolution UV imagery, is described. The experiments were conducted during a series of three sounding rocket flights. All three flights yielded excellent images in the UV range, showing unprecedented spatial resolution. The second flight recorded the X-ray spectrum of a solar flare, and the third that of an active region. A normal incidence multi-layer mirror was used during the third flight to make the first astronomical X-ray observations using this new technique.
Optic for an endoscope/borescope having high resolution and narrow field of view
Stone, Gary F.; Trebes, James E.
2003-10-28
An optic having optimized high spatial resolution, minimal nonlinear magnification distortion while at the same time having a limited chromatic focal shift or chromatic aberrations. The optic located at the distal end of an endoscopic inspection tool permits a high resolution, narrow field of view image for medical diagnostic applications, compared to conventional optics for endoscopic instruments which provide a wide field of view, low resolution image. The image coverage is over a narrow (<20 degrees) field of view with very low optical distortion (<5% pin cushion or barrel distortion. The optic is also optimized for best color correction as well as to aid medical diagnostics.
Yang, Cheng-Xiong; Liu, Chang; Cao, Yi-Meng; Yan, Xiu-Ping
2015-08-07
A simple and facile room-temperature solution-phase synthesis was developed to fabricate a spherical covalent organic framework with large surface area, good solvent stability and high thermostability for high-resolution chromatographic separation of diverse important industrial analytes including alkanes, cyclohexane and benzene, α-pinene and β-pinene, and alcohols with high column efficiency and good precision.
Pinto, Francisco; Mielewczik, Michael; Liebisch, Frank; Walter, Achim; Greven, Hartmut; Rascher, Uwe
2013-01-01
Most spectral data for the amphibian integument are limited to the visible spectrum of light and have been collected using point measurements with low spatial resolution. In the present study a dual camera setup consisting of two push broom hyperspectral imaging systems was employed, which produces reflectance images between 400 and 2500 nm with high spectral and spatial resolution and a high dynamic range. We briefly introduce the system and document the high efficiency of this technique analyzing exemplarily the spectral reflectivity of the integument of three arboreal anuran species (Litoria caerulea, Agalychnis callidryas and Hyla arborea), all of which appear green to the human eye. The imaging setup generates a high number of spectral bands within seconds and allows non-invasive characterization of spectral characteristics with relatively high working distance. Despite the comparatively uniform coloration, spectral reflectivity between 700 and 1100 nm differed markedly among the species. In contrast to H. arborea, L. caerulea and A. callidryas showed reflection in this range. For all three species, reflectivity above 1100 nm is primarily defined by water absorption. Furthermore, the high resolution allowed examining even small structures such as fingers and toes, which in A. callidryas showed an increased reflectivity in the near infrared part of the spectrum. Hyperspectral imaging was found to be a very useful alternative technique combining the spectral resolution of spectrometric measurements with a higher spatial resolution. In addition, we used Digital Infrared/Red-Edge Photography as new simple method to roughly determine the near infrared reflectivity of frog specimens in field, where hyperspectral imaging is typically difficult.
Zhang, Fangzheng; Guo, Qingshui; Pan, Shilong
2017-10-23
Real-time and high-resolution target detection is highly desirable in modern radar applications. Electronic techniques have encountered grave difficulties in the development of such radars, which strictly rely on a large instantaneous bandwidth. In this article, a photonics-based real-time high-range-resolution radar is proposed with optical generation and processing of broadband linear frequency modulation (LFM) signals. A broadband LFM signal is generated in the transmitter by photonic frequency quadrupling, and the received echo is de-chirped to a low frequency signal by photonic frequency mixing. The system can operate at a high frequency and a large bandwidth while enabling real-time processing by low-speed analog-to-digital conversion and digital signal processing. A conceptual radar is established. Real-time processing of an 8-GHz LFM signal is achieved with a sampling rate of 500 MSa/s. Accurate distance measurement is implemented with a maximum error of 4 mm within a range of ~3.5 meters. Detection of two targets is demonstrated with a range-resolution as high as 1.875 cm. We believe the proposed radar architecture is a reliable solution to overcome the limitations of current radar on operation bandwidth and processing speed, and it is hopefully to be used in future radars for real-time and high-resolution target detection and imaging.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gao, Yanhong; Leung, Lai-Yung R.; Zhang, Yongxin
2015-05-15
Net precipitation (precipitation minus evapotranspiration, P-E) changes between 1979 and 2011 from a high resolution regional climate simulation and its reanalysis forcing are analyzed over the Tibet Plateau (TP) and compared to the global land data assimilation system (GLDAS) product. The high resolution simulation better resolves precipitation changes than its coarse resolution forcing, which contributes dominantly to the improved P-E change in the regional simulation compared to the global reanalysis. Hence, the former may provide better insights about the drivers of P-E changes. The mechanism behind the P-E changes is explored by decomposing the column integrated moisture flux convergence intomore » thermodynamic, dynamic, and transient eddy components. High-resolution climate simulation improves the spatial pattern of P-E changes over the best available global reanalysis. High-resolution climate simulation also facilitates new and substantial findings regarding the role of thermodynamics and transient eddies in P-E changes reflected in observed changes in major river basins fed by runoff from the TP. The analysis revealed the contrasting convergence/divergence changes between the northwestern and southeastern TP and feedback through latent heat release as an important mechanism leading to the mean P-E changes in the TP.« less
Chemical speciation using high energy resolution PIXE spectroscopy in the tender X-ray range
NASA Astrophysics Data System (ADS)
Kavčič, Matjaž; Petric, Marko; Vogel-Mikuš, Katarina
2018-02-01
High energy resolution X-ray emission spectroscopy employing wavelength dispersive (WDS) crystal spectrometers can provide energy resolution on the level of core-hole lifetime broadening of the characteristic emission lines. While crystal spectrometers have been traditionally used in combination with electron excitation for major and minor element analysis, they have been rarely considered in proton induced X-ray emission (PIXE) trace element analysis mainly due to low detection efficiency. Compared to the simplest flat crystal WDS spectrometer the efficiency can be improved by employing cylindrically or even spherically curved crystals in combination with position sensitive X-ray detectors. When such spectrometer is coupled to MeV proton excitation, chemical bonding effects are revealed in the high energy resolution spectra yielding opportunity to extend the analytical capabilities of PIXE technique also towards chemical state analysis. In this contribution we will focus on the high energy resolution PIXE (HR-PIXE) spectroscopy in the tender X-ray range performed in our laboratory with our home-built tender X-ray emission spectrometer. Some general properties of high energy resolution PIXE spectroscopy in the tender X-ray range are presented followed by an example of sulfur speciation in biological tissue illustrating the capabilities as well as limitations of HR-PIXE method used for chemical speciation in the tender X-ray range.
Kaur, Parminder; Kiselar, Janna; Yang, Sichun; Chance, Mark R.
2015-01-01
Hydroxyl radical footprinting based MS for protein structure assessment has the goal of understanding ligand induced conformational changes and macromolecular interactions, for example, protein tertiary and quaternary structure, but the structural resolution provided by typical peptide-level quantification is limiting. In this work, we present experimental strategies using tandem-MS fragmentation to increase the spatial resolution of the technique to the single residue level to provide a high precision tool for molecular biophysics research. Overall, in this study we demonstrated an eightfold increase in structural resolution compared with peptide level assessments. In addition, to provide a quantitative analysis of residue based solvent accessibility and protein topography as a basis for high-resolution structure prediction; we illustrate strategies of data transformation using the relative reactivity of side chains as a normalization strategy and predict side-chain surface area from the footprinting data. We tested the methods by examination of Ca+2-calmodulin showing highly significant correlations between surface area and side-chain contact predictions for individual side chains and the crystal structure. Tandem ion based hydroxyl radical footprinting-MS provides quantitative high-resolution protein topology information in solution that can fill existing gaps in structure determination for large proteins and macromolecular complexes. PMID:25687570
NASA Astrophysics Data System (ADS)
Elarab, Manal; Ticlavilca, Andres M.; Torres-Rua, Alfonso F.; Maslova, Inga; McKee, Mac
2015-12-01
Precision agriculture requires high-resolution information to enable greater precision in the management of inputs to production. Actionable information about crop and field status must be acquired at high spatial resolution and at a temporal frequency appropriate for timely responses. In this study, high spatial resolution imagery was obtained through the use of a small, unmanned aerial system called AggieAirTM. Simultaneously with the AggieAir flights, intensive ground sampling for plant chlorophyll was conducted at precisely determined locations. This study reports the application of a relevance vector machine coupled with cross validation and backward elimination to a dataset composed of reflectance from high-resolution multi-spectral imagery (VIS-NIR), thermal infrared imagery, and vegetative indices, in conjunction with in situ SPAD measurements from which chlorophyll concentrations were derived, to estimate chlorophyll concentration from remotely sensed data at 15-cm resolution. The results indicate that a relevance vector machine with a thin plate spline kernel type and kernel width of 5.4, having LAI, NDVI, thermal and red bands as the selected set of inputs, can be used to spatially estimate chlorophyll concentration with a root-mean-squared-error of 5.31 μg cm-2, efficiency of 0.76, and 9 relevance vectors.
A high-resolution imaging technique using a whole-body, research photon counting detector CT system
NASA Astrophysics Data System (ADS)
Leng, S.; Yu, Z.; Halaweish, A.; Kappler, S.; Hahn, K.; Henning, A.; Li, Z.; Lane, J.; Levin, D. L.; Jorgensen, S.; Ritman, E.; McCollough, C.
2016-03-01
A high-resolution (HR) data collection mode has been introduced to a whole-body, research photon-counting-detector CT system installed in our laboratory. In this mode, 64 rows of 0.45 mm x 0.45 mm detector pixels were used, which corresponded to a pixel size of 0.25 mm x 0.25 mm at the iso-center. Spatial resolution of this HR mode was quantified by measuring the MTF from a scan of a 50 micron wire phantom. An anthropomorphic lung phantom, cadaveric swine lung, temporal bone and heart specimens were scanned using the HR mode, and image quality was subjectively assessed by two experienced radiologists. High spatial resolution of the HR mode was evidenced by the MTF measurement, with 15 lp/cm and 20 lp/cm at 10% and 2% modulation. Images from anthropomorphic phantom and cadaveric specimens showed clear delineation of small structures, such as lung vessels, lung nodules, temporal bone structures, and coronary arteries. Temporal bone images showed critical anatomy (i.e. stapes superstructure) that was clearly visible in the PCD system. These results demonstrated the potential application of this imaging mode in lung, temporal bone, and vascular imaging. Other clinical applications that require high spatial resolution, such as musculoskeletal imaging, may also benefit from this high resolution mode.
Martin, A.D.
1986-05-09
Method and apparatus are provided for generating an output pulse following a trigger pulse at a time delay interval preset with a resolution which is high relative to a low resolution available from supplied clock pulses. A first lumped constant delay provides a first output signal at predetermined interpolation intervals corresponding to the desired high resolution time interval. Latching circuits latch the high resolution data to form a first synchronizing data set. A selected time interval has been preset to internal counters and corrected for circuit propagation delay times having the same order of magnitude as the desired high resolution. Internal system clock pulses count down the counters to generate an internal pulse delayed by an internal which is functionally related to the preset time interval. A second LCD corrects the internal signal with the high resolution time delay. A second internal pulse is then applied to a third LCD to generate a second set of synchronizing data which is complementary with the first set of synchronizing data for presentation to logic circuits. The logic circuits further delay the internal output signal with the internal pulses. The final delayed output signal thereafter enables the output pulse generator to produce the desired output pulse at the preset time delay interval following input of the trigger pulse.
Los Angeles megacity: a high-resolution land–atmosphere modelling system for urban CO 2 emissions
Feng, Sha; Lauvaux, Thomas; Newman, Sally; ...
2016-07-22
Megacities are major sources of anthropogenic fossil fuel CO 2 (FFCO 2) emissions. The spatial extents of these large urban systems cover areas of 10 000 km 2 or more with complex topography and changing landscapes. We present a high-resolution land–atmosphere modelling system for urban CO 2 emissions over the Los Angeles (LA) megacity area. The Weather Research and Forecasting (WRF)-Chem model was coupled to a very high-resolution FFCO 2 emission product, Hestia-LA, to simulate atmospheric CO 2 concentrations across the LA megacity at spatial resolutions as fine as ~1 km. We evaluated multiple WRF configurations, selecting one that minimizedmore » errors in wind speed, wind direction, and boundary layer height as evaluated by its performance against meteorological data collected during the CalNex-LA campaign (May–June 2010). Our results show no significant difference between moderate-resolution (4 km) and high-resolution (1.3 km) simulations when evaluated against surface meteorological data, but the high-resolution configurations better resolved planetary boundary layer heights and vertical gradients in the horizontal mean winds. We coupled our WRF configuration with the Vulcan 2.2 (10 km resolution) and Hestia-LA (1.3 km resolution) fossil fuel CO 2 emission products to evaluate the impact of the spatial resolution of the CO 2 emission products and the meteorological transport model on the representation of spatiotemporal variability in simulated atmospheric CO 2 concentrations. We find that high spatial resolution in the fossil fuel CO 2 emissions is more important than in the atmospheric model to capture CO 2 concentration variability across the LA megacity. Finally, we present a novel approach that employs simultaneous correlations of the simulated atmospheric CO 2 fields to qualitatively evaluate the greenhouse gas measurement network over the LA megacity. Spatial correlations in the atmospheric CO 2 fields reflect the coverage of individual measurement sites when a statistically significant number of sites observe emissions from a specific source or location. We conclude that elevated atmospheric CO 2 concentrations over the LA megacity are composed of multiple fine-scale plumes rather than a single homogenous urban dome. Furthermore, we conclude that FFCO 2 emissions monitoring in the LA megacity requires FFCO 2 emissions modelling with ~1 km resolution because coarser-resolution emissions modelling tends to overestimate the observational constraints on the emissions estimates.« less
Los Angeles megacity: a high-resolution land–atmosphere modelling system for urban CO 2 emissions
DOE Office of Scientific and Technical Information (OSTI.GOV)
Feng, Sha; Lauvaux, Thomas; Newman, Sally
Megacities are major sources of anthropogenic fossil fuel CO 2 (FFCO 2) emissions. The spatial extents of these large urban systems cover areas of 10 000 km 2 or more with complex topography and changing landscapes. We present a high-resolution land–atmosphere modelling system for urban CO 2 emissions over the Los Angeles (LA) megacity area. The Weather Research and Forecasting (WRF)-Chem model was coupled to a very high-resolution FFCO 2 emission product, Hestia-LA, to simulate atmospheric CO 2 concentrations across the LA megacity at spatial resolutions as fine as ~1 km. We evaluated multiple WRF configurations, selecting one that minimizedmore » errors in wind speed, wind direction, and boundary layer height as evaluated by its performance against meteorological data collected during the CalNex-LA campaign (May–June 2010). Our results show no significant difference between moderate-resolution (4 km) and high-resolution (1.3 km) simulations when evaluated against surface meteorological data, but the high-resolution configurations better resolved planetary boundary layer heights and vertical gradients in the horizontal mean winds. We coupled our WRF configuration with the Vulcan 2.2 (10 km resolution) and Hestia-LA (1.3 km resolution) fossil fuel CO 2 emission products to evaluate the impact of the spatial resolution of the CO 2 emission products and the meteorological transport model on the representation of spatiotemporal variability in simulated atmospheric CO 2 concentrations. We find that high spatial resolution in the fossil fuel CO 2 emissions is more important than in the atmospheric model to capture CO 2 concentration variability across the LA megacity. Finally, we present a novel approach that employs simultaneous correlations of the simulated atmospheric CO 2 fields to qualitatively evaluate the greenhouse gas measurement network over the LA megacity. Spatial correlations in the atmospheric CO 2 fields reflect the coverage of individual measurement sites when a statistically significant number of sites observe emissions from a specific source or location. We conclude that elevated atmospheric CO 2 concentrations over the LA megacity are composed of multiple fine-scale plumes rather than a single homogenous urban dome. Furthermore, we conclude that FFCO 2 emissions monitoring in the LA megacity requires FFCO 2 emissions modelling with ~1 km resolution because coarser-resolution emissions modelling tends to overestimate the observational constraints on the emissions estimates.« less
High density FTA plates serve as efficient long-term sample storage for HLA genotyping.
Lange, V; Arndt, K; Schwarzelt, C; Boehme, I; Giani, A S; Schmidt, A H; Ehninger, G; Wassmuth, R
2014-02-01
Storage of dried blood spots (DBS) on high-density FTA(®) plates could constitute an appealing alternative to frozen storage. However, it remains controversial whether DBS are suitable for high-resolution sequencing of human leukocyte antigen (HLA) alleles. Therefore, we extracted DNA from DBS that had been stored for up to 4 years, using six different methods. We identified those extraction methods that recovered sufficient high-quality DNA for reliable high-resolution HLA sequencing. Further, we confirmed that frozen whole blood samples that had been stored for several years can be transferred to filter paper without compromising HLA genotyping upon extraction. Concluding, DNA derived from high-density FTA(®) plates is suitable for high-resolution HLA sequencing, provided that appropriate extraction protocols are employed. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
Stickel, Jennifer R; Qi, Jinyi; Cherry, Simon R
2007-01-01
With the increasing use of in vivo imaging in mouse models of disease, there are many interesting applications that demand imaging of organs and tissues with submillimeter resolution. Though there are other contributing factors, the spatial resolution in small-animal PET is still largely determined by the detector pixel dimensions. In this work, a pair of lutetium oxyorthosilicate (LSO) arrays with 0.5-mm pixels was coupled to multichannel photomultiplier tubes and evaluated for use as high-resolution PET detectors. Flood histograms demonstrated that most crystals were clearly identifiable. Energy resolution varied from 22% to 38%. The coincidence timing resolution was 1.42-ns full width at half maximum (FWHM). The intrinsic spatial resolution was 0.68-mm FWHM as measured with a 30-gauge needle filled with (18)F. The improvement in spatial resolution in a tomographic setting is demonstrated using images of a line source phantom reconstructed with filtered backprojection and compared with images obtained from 2 dedicated small-animal PET scanners. Finally, a projection image of the mouse foot is shown to demonstrate the application of these 0.5-mm LSO detectors to a biologic task. A pair of highly pixelated LSO detections has been constructed and characterized for use as high-spatial-resolution PET detectors. It appears that small-animal PET systems capable of a FWHM spatial resolution of 600 microm or less are feasible and should be pursued.
Analysis and characterization of high-resolution and high-aspect-ratio imaging fiber bundles.
Motamedi, Nojan; Karbasi, Salman; Ford, Joseph E; Lomakin, Vitaliy
2015-11-10
High-contrast imaging fiber bundles (FBs) are characterized and modeled for wide-angle and high-resolution imaging applications. Scanning electron microscope images of FB cross sections are taken to measure physical parameters and verify the variations of irregular fibers due to the fabrication process. Modal analysis tools are developed that include irregularities in the fiber core shapes and provide results in agreement with experimental measurements. The modeling demonstrates that the irregular fibers significantly outperform a perfectly regular "ideal" array. Using this method, FBs are designed that can provide high contrast with core pitches of only a few wavelengths of the guided light. Structural modifications of the commercially available FB can reduce the core pitch by 60% for higher resolution image relay.
High-resolution nuclear magnetic resonance studies of proteins.
Jonas, Jiri
2002-03-25
The combination of advanced high-resolution nuclear magnetic resonance (NMR) techniques with high-pressure capability represents a powerful experimental tool in studies of protein folding. This review is organized as follows: after a general introduction of high-pressure, high-resolution NMR spectroscopy of proteins, the experimental part deals with instrumentation. The main section of the review is devoted to NMR studies of reversible pressure unfolding of proteins with special emphasis on pressure-assisted cold denaturation and the detection of folding intermediates. Recent studies investigating local perturbations in proteins and the experiments following the effects of point mutations on pressure stability of proteins are also discussed. Ribonuclease A, lysozyme, ubiquitin, apomyoglobin, alpha-lactalbumin and troponin C were the model proteins investigated.
High Temporal and Spatial Resolution Global GPS TEC Observations of the 2015 St. Patrick Day Storm
NASA Astrophysics Data System (ADS)
Vierinen, J.
2015-12-01
High spatiotemperal resolution global GPS TEC measurements of the 2015 St. Patrick's day storm are presented. The high resolution data is useful, as it clearly shows the high latitude convection patterns, the equatorward progression of the auroral region, the tongue of ionization, as well as the increased electron density in the equatorial anomaly region. The measurements are compared with high power large aperture radar and passive radar measurements of coherent and incoherent scatter at Millstone Hill. Regions of fast convection identified in the GPS TEC data are found to coincide with coherent scatter in both radar data. Convection velocities determined from GPS TEC are compared with those obtained from incoherent scatter radar measurements.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Foxley, Sean, E-mail: sean.foxley@ndcn.ox.ac.uk; Karczmar, Gregory S.; Domowicz, Miriam
Purpose: Widely used MRI methods show brain morphology both in vivo and ex vivo at very high resolution. Many of these methods (e.g., T{sub 2}{sup *}-weighted imaging, phase-sensitive imaging, or susceptibility-weighted imaging) are sensitive to local magnetic susceptibility gradients produced by subtle variations in tissue composition. However, the spectral resolution of commonly used methods is limited to maintain reasonable run-time combined with very high spatial resolution. Here, the authors report on data acquisition at increased spectral resolution, with 3-dimensional high spectral and spatial resolution MRI, in order to analyze subtle variations in water proton resonance frequency and lineshape that reflectmore » local anatomy. The resulting information compliments previous studies based on T{sub 2}{sup *} and resonance frequency. Methods: The proton free induction decay was sampled at high resolution and Fourier transformed to produce a high-resolution water spectrum for each image voxel in a 3D volume. Data were acquired using a multigradient echo pulse sequence (i.e., echo-planar spectroscopic imaging) with a spatial resolution of 50 × 50 × 70 μm{sup 3} and spectral resolution of 3.5 Hz. Data were analyzed in the spectral domain, and images were produced from the various Fourier components of the water resonance. This allowed precise measurement of local variations in water resonance frequency and lineshape, at the expense of significantly increased run time (16–24 h). Results: High contrast T{sub 2}{sup *}-weighted images were produced from the peak of the water resonance (peak height image), revealing a high degree of anatomical detail, specifically in the hippocampus and cerebellum. In images produced from Fourier components of the water resonance at −7.0 Hz from the peak, the contrast between deep white matter tracts and the surrounding tissue is the reverse of the contrast in water peak height images. This indicates the presence of a shoulder in the water resonance that is not present at +7.0 Hz and may be specific to white matter anatomy. Moreover, a frequency shift of 6.76 ± 0.55 Hz was measured between the molecular and granular layers of the cerebellum. This shift is demonstrated in corresponding spectra; water peaks from voxels in the molecular and granular layers are consistently 2 bins apart (7.0 Hz, as dictated by the spectral resolution) from one another. Conclusions: High spectral and spatial resolution MR imaging has the potential to accurately measure the changes in the water resonance in small voxels. This information can guide optimization and interpretation of more commonly used, more rapid imaging methods that depend on image contrast produced by local susceptibility gradients. In addition, with improved sampling methods, high spectral and spatial resolution data could be acquired in reasonable run times, and used for in vivo scans to increase sensitivity to variations in local susceptibility.« less
Optical coherence microscope for invariant high resolution in vivo skin imaging
NASA Astrophysics Data System (ADS)
Murali, S.; Lee, K. S.; Meemon, P.; Rolland, J. P.
2008-02-01
A non-invasive, reliable and affordable imaging system with the capability of detecting skin pathologies such as skin cancer would be a valuable tool to use for pre-screening and diagnostic applications. Optical Coherence Microscopy (OCM) is emerging as a building block for in vivo optical diagnosis, where high numerical aperture optics is introduced in the sample arm to achieve high lateral resolution. While high numerical aperture optics enables realizing high lateral resolution at the focus point, dynamic focusing is required to maintain the target lateral resolution throughout the depth of the sample being imaged. In this paper, we demonstrate the ability to dynamically focus in real-time with no moving parts to a depth of up to 2mm in skin-equivalent tissue in order to achieve 3.5μm lateral resolution throughout an 8 cubic millimeter sample. The built-in dynamic focusing ability is provided by an addressable liquid lens embedded in custom-designed optics which was designed for a broadband laser source of 120 nm bandwidth centered at around 800nm. The imaging probe was designed to be low-cost and portable. Design evaluation and tolerance analysis results show that the probe is robust to manufacturing errors and produces consistent high performance throughout the imaging volume.
High-resolution remote sensing of water quality in the San Francisco Bay-Delta Estuary
Fichot, Cédric G.; Downing, Bryan D.; Bergamaschi, Brian; Windham-Myers, Lisamarie; Marvin-DiPasquale, Mark C.; Thompson, David R.; Gierach, Michelle M.
2015-01-01
The San Francisco Bay–Delta Estuary watershed is a major source of freshwater for California and a profoundly human-impacted environment. The water quality monitoring that is critical to the management of this important water resource and ecosystem relies primarily on a system of fixed water-quality monitoring stations, but the limited spatial coverage often hinders understanding. Here, we show how the latest technology in visible/near-infrared imaging spectroscopy can facilitate water quality monitoring in this highly dynamic and heterogeneous system by enabling simultaneous depictions of several water quality indicators at very high spatial resolution. The airborne portable remote imaging spectrometer (PRISM) was used to derive high-spatial-resolution (2.6 × 2.6 m) distributions of turbidity, and dissolved organic carbon (DOC) and chlorophyll-a concentrations in a wetland-influenced region of this estuary. A filter-passing methylmercury vs DOC relationship was also developed using in situ samples and enabled the high-spatial-resolution depiction of surface methylmercury concentrations in this area. The results illustrate how high-resolution imaging spectroscopy can inform management and policy development in important inland and estuarine water bodies by facilitating the detection of point- and nonpoint-source pollution, and by providing data to help assess the complex impacts of wetland restoration and climate change on water quality and ecosystem productivity.
Bullen, A; Patel, S S; Saggau, P
1997-07-01
The design and implementation of a high-speed, random-access, laser-scanning fluorescence microscope configured to record fast physiological signals from small neuronal structures with high spatiotemporal resolution is presented. The laser-scanning capability of this nonimaging microscope is provided by two orthogonal acousto-optic deflectors under computer control. Each scanning point can be randomly accessed and has a positioning time of 3-5 microseconds. Sampling time is also computer-controlled and can be varied to maximize the signal-to-noise ratio. Acquisition rates up to 200k samples/s at 16-bit digitizing resolution are possible. The spatial resolution of this instrument is determined by the minimal spot size at the level of the preparation (i.e., 2-7 microns). Scanning points are selected interactively from a reference image collected with differential interference contrast optics and a video camera. Frame rates up to 5 kHz are easily attainable. Intrinsic variations in laser light intensity and scanning spot brightness are overcome by an on-line signal-processing scheme. Representative records obtained with this instrument by using voltage-sensitive dyes and calcium indicators demonstrate the ability to make fast, high-fidelity measurements of membrane potential and intracellular calcium at high spatial resolution (2 microns) without any temporal averaging.
NASA Astrophysics Data System (ADS)
Passegger, Vera Maria; Reiners, Ansgar; Jeffers, Sandra V.; Wende, Sebastian; Schöfer, Patrick; Amado, Pedro J.; Caballero, Jose A.; Montes, David; Mundt, Reinhard; Ribas, Ignasi; Quirrenbach, Andreas
2016-07-01
CARMENES (Calar Alto high-Resolution search for M dwarfs with Exoearths with Near-infrared and optical Échelle Spectrographs) started a new planet survey on M-dwarfs in January this year. The new high-resolution spectrographs are operating in the visible and near-infrared at Calar Alto Observatory. They will perform high-accuracy radial-velocity measurements (goal 1 m s-1) of about 300 M-dwarfs with the aim to detect low-mass planets within habitable zones. We characterised the candidate sample for CARMENES and provide fundamental parameters for these stars in order to constrain planetary properties and understand star-planet systems. Using state-of-the-art model atmospheres (PHOENIX-ACES) and χ2-minimization with a downhill-simplex method we determine effective temperature, surface gravity and metallicity [Fe/H] for high-resolution spectra of around 480 stars of spectral types M0.0-6.5V taken with FEROS, CAFE and HRS. We find good agreement between the models and our observed high-resolution spectra. We show the performance of the algorithm, as well as results, parameter and spectral type distributions for the CARMENES candidate sample, which is used to define the CARMENES target sample. We also present first preliminary results obtained from CARMENES spectra.
Bullen, A; Patel, S S; Saggau, P
1997-01-01
The design and implementation of a high-speed, random-access, laser-scanning fluorescence microscope configured to record fast physiological signals from small neuronal structures with high spatiotemporal resolution is presented. The laser-scanning capability of this nonimaging microscope is provided by two orthogonal acousto-optic deflectors under computer control. Each scanning point can be randomly accessed and has a positioning time of 3-5 microseconds. Sampling time is also computer-controlled and can be varied to maximize the signal-to-noise ratio. Acquisition rates up to 200k samples/s at 16-bit digitizing resolution are possible. The spatial resolution of this instrument is determined by the minimal spot size at the level of the preparation (i.e., 2-7 microns). Scanning points are selected interactively from a reference image collected with differential interference contrast optics and a video camera. Frame rates up to 5 kHz are easily attainable. Intrinsic variations in laser light intensity and scanning spot brightness are overcome by an on-line signal-processing scheme. Representative records obtained with this instrument by using voltage-sensitive dyes and calcium indicators demonstrate the ability to make fast, high-fidelity measurements of membrane potential and intracellular calcium at high spatial resolution (2 microns) without any temporal averaging. Images FIGURE 6 PMID:9199810
High resolution x-ray and gamma ray imaging using diffraction lenses with mechanically bent crystals
Smither, Robert K [Hinsdale, IL
2008-12-23
A method for high spatial resolution imaging of a plurality of sources of x-ray and gamma-ray radiation is provided. High quality mechanically bent diffracting crystals of 0.1 mm radial width are used for focusing the radiation and directing the radiation to an array of detectors which is used for analyzing their addition to collect data as to the location of the source of radiation. A computer is used for converting the data to an image. The invention also provides for the use of a multi-component high resolution detector array and for narrow source and detector apertures.
Small-Scale Tropopause Dynamics and TOMS Total Ozone
NASA Technical Reports Server (NTRS)
Stanford, John L.
2002-01-01
This project used Earth Probe Total Ozone Mapping Spectrometer (EP TOMS) along-track ozone retrievals, in conjunction with ancillary meteorological fields and modeling studies, for high resolution investigations of upper troposphere and lower stratosphere dynamics. Specifically, high resolution along-track (Level 2) EP TOMS data were used to investigate the beautiful fine-scale structure in constituent and meteorological fields prominent in the evolution of highly non-linear baroclinic storm systems. Comparison was made with high resolution meteorological models. The analyses provide internal consistency checks and validation of the EP TOMS data which are vital for monitoring ozone depletion in both polar and midlatitude regions.
Yoo, Sylvia H; Rootman, Dan B; Goh, Alice; Savar, Aaron; Goldberg, Robert A
2016-01-01
A patient was found to have a metallic foreign body in the left anterior orbit on CT imaging, but the foreign body was not evident on clinical examination. On high-resolution ultrasonography, an object was identified in the left upper eyelid; however, the typical shadow with metallic foreign bodies was not seen. A high-power oscillating magnet was then applied to the eyelid, which revealed a subcutaneous metallic foreign body in the left upper eyelid. When used in conjunction, the high-resolution ultrasound and oscillating magnet successfully localized and facilitated retrieval of the metallic foreign body from the left upper eyelid.
Re-scan confocal microscopy: scanning twice for better resolution.
De Luca, Giulia M R; Breedijk, Ronald M P; Brandt, Rick A J; Zeelenberg, Christiaan H C; de Jong, Babette E; Timmermans, Wendy; Azar, Leila Nahidi; Hoebe, Ron A; Stallinga, Sjoerd; Manders, Erik M M
2013-01-01
We present a new super-resolution technique, Re-scan Confocal Microscopy (RCM), based on standard confocal microscopy extended with an optical (re-scanning) unit that projects the image directly on a CCD-camera. This new microscope has improved lateral resolution and strongly improved sensitivity while maintaining the sectioning capability of a standard confocal microscope. This simple technology is typically useful for biological applications where the combination high-resolution and high-sensitivity is required.
Retinal optical coherence tomography at 1 μm with dynamic focus control and axial motion tracking
NASA Astrophysics Data System (ADS)
Cua, Michelle; Lee, Sujin; Miao, Dongkai; Ju, Myeong Jin; Mackenzie, Paul J.; Jian, Yifan; Sarunic, Marinko V.
2016-02-01
High-resolution optical coherence tomography (OCT) retinal imaging is important to noninvasively visualize the various retinal structures to aid in better understanding of the pathogenesis of vision-robbing diseases. However, conventional OCT systems have a trade-off between lateral resolution and depth-of-focus. In this report, we present the development of a focus-stacking OCT system with automatic focus optimization for high-resolution, extended-focal-range clinical retinal imaging by incorporating a variable-focus liquid lens into the sample arm optics. Retinal layer tracking and selection was performed using a graphics processing unit accelerated processing platform for focus optimization, providing real-time layer-specific en face visualization. After optimization, multiple volumes focused at different depths were acquired, registered, and stitched together to yield a single, high-resolution focus-stacked dataset. Using this system, we show high-resolution images of the retina and optic nerve head, from which we extracted clinically relevant parameters such as the nerve fiber layer thickness and lamina cribrosa microarchitecture.
Electro-optical design of a long slit streak tube
NASA Astrophysics Data System (ADS)
Tian, Liping; Tian, Jinshou; Wen, Wenlong; Chen, Ping; Wang, Xing; Hui, Dandan; Wang, Junfeng
2017-11-01
A small size and long slit streak tube with high spatial resolution was designed and optimized. Curved photocathode and screen were adopted to increase the photocathode working area and spatial resolution. High physical temporal resolution obtained by using a slit accelerating electrode. Deflection sensitivity of the streak tube was improved by adopting two-folded deflection plates. The simulations indicate that the photocathode effective working area can reach 30mm × 5mm. The static spatial resolution is higher than 40lp/mm and 12lp/mm along scanning and slit directions respectively while the physical temporal resolution is higher than 60ps. The magnification is 0.75 and 0.77 in scanning and slit directions. And also, the deflection sensitivity is as high as 37mm/kV. The external dimension of the streak tube are only ∅74mm×231mm. Thus, it can be applied to laser imaging radar system for large field of view and high range precision detection.
Sakadzić, Sava; Roussakis, Emmanuel; Yaseen, Mohammad A; Mandeville, Emiri T; Srinivasan, Vivek J; Arai, Ken; Ruvinskaya, Svetlana; Devor, Anna; Lo, Eng H; Vinogradov, Sergei A; Boas, David A
2010-09-01
Measurements of oxygen partial pressure (pO(2)) with high temporal and spatial resolution in three dimensions is crucial for understanding oxygen delivery and consumption in normal and diseased brain. Among existing pO(2) measurement methods, phosphorescence quenching is optimally suited for the task. However, previous attempts to couple phosphorescence with two-photon laser scanning microscopy have faced substantial difficulties because of extremely low two-photon absorption cross-sections of conventional phosphorescent probes. Here we report to our knowledge the first practical in vivo two-photon high-resolution pO(2) measurements in small rodents' cortical microvasculature and tissue, made possible by combining an optimized imaging system with a two-photon-enhanced phosphorescent nanoprobe. The method features a measurement depth of up to 250 microm, sub-second temporal resolution and requires low probe concentration. The properties of the probe allowed for direct high-resolution measurement of cortical extravascular (tissue) pO(2), opening many possibilities for functional metabolic brain studies.
Retinal optical coherence tomography at 1 μm with dynamic focus control and axial motion tracking.
Cua, Michelle; Lee, Sujin; Miao, Dongkai; Ju, Myeong Jin; Mackenzie, Paul J; Jian, Yifan; Sarunic, Marinko V
2016-02-01
High-resolution optical coherence tomography (OCT) retinal imaging is important to noninvasively visualize the various retinal structures to aid in better understanding of the pathogenesis of vision-robbing diseases. However, conventional OCT systems have a trade-off between lateral resolution and depth-of-focus. In this report, we present the development of a focus-stacking OCT system with automatic focus optimization for high-resolution, extended-focal-range clinical retinal imaging by incorporating a variable-focus liquid lens into the sample arm optics. Retinal layer tracking and selection was performed using a graphics processing unit accelerated processing platform for focus optimization, providing real-time layer-specific en face visualization. After optimization, multiple volumes focused at different depths were acquired, registered, and stitched together to yield a single, high-resolution focus-stacked dataset. Using this system, we show high-resolution images of the retina and optic nerve head, from which we extracted clinically relevant parameters such as the nerve fiber layer thickness and lamina cribrosa microarchitecture.
NASA Astrophysics Data System (ADS)
Ni, Guangming; Liu, Lin; Zhang, Jing; Liu, Juanxiu; Liu, Yong
2018-01-01
With the development of the liquid crystal display (LCD) module industry, LCD modules become more and more precise with larger sizes, which demands harsh imaging requirements for automated optical inspection (AOI). Here, we report a high-resolution and clearly focused imaging optomechatronics for precise LCD module bonding AOI inspection. It first presents and achieves high-resolution imaging for LCD module bonding AOI inspection using a line scan camera (LSC) triggered by a linear optical encoder, self-adaptive focusing for the whole large imaging region using LSC, and a laser displacement sensor, which reduces the requirements of machining, assembly, and motion control of AOI devices. Results show that this system can directly achieve clearly focused imaging for AOI inspection of large LCD module bonding with 0.8 μm image resolution, 2.65-mm scan imaging width, and no limited imaging width theoretically. All of these are significant for AOI inspection in the LCD module industry and other fields that require imaging large regions with high resolution.
Dual-comb spectroscopy of laser-induced plasmas
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bergevin, Jenna; Wu, Tsung-Han; Yeak, Jeremy
Dual-comb spectroscopy has become a powerful spectroscopic technique in applications that rely on its broad spectral coverage combined with high frequency resolution capabilities. Experiments to date have primarily focused on detection and analysis of multiple gas species under semi-static conditions, with applications ranging from environmental monitoring of greenhouse gases to high resolution molecular spectroscopy. Here, we utilize dual-comb spectroscopy to demonstrate broadband, high-resolution, and time-resolved measurements in a laser induced plasma for the first time. As a first demonstration, we simultaneously detect trace amounts of Rb and K in solid samples with a single laser ablation shot, with transitions separatedmore » by over 6 THz (13 nm) and spectral resolution sufficient to resolve isotopic and ground state hyperfine splittings of the Rb D2 line. This new spectroscopic approach offers the broad spectral coverage found in the powerful techniques of laser-induced breakdown spectroscopy (LIBS) while providing the high-resolution and accuracy of cw laser-based spectroscopies.« less
High-resolution seismic reflection profiling for mapping shallow aquifers in Lee County, Florida
Missimer, T.M.; Gardner, Richard Alfred
1976-01-01
High-resolution continuous seismic reflection profiling equipment was utilized to define the configuration of sedimentary layers underlying part of Lee County, Florida. About 45 miles (72 kilometers) of profile were made on the Caloosahatchee River Estuary and San Carlos Bay. Two different acoustic energy sources, a high resolution boomer and a 45-electrode high resolution sparker, both having a power input of 300 joules, were used to obtain both adequate penetration and good resolution. The seismic profiles show that much of the strata of middle Miocene to Holocene age apparently are extensively folded but not faulted. Initial interpretations indicate that: (1) the top of the Hawthorn Formation (which contains the upper Hawthorn aquifer) has much relief due chiefly to apparent folding; (2) the limestone, sandstone, and unconsolidated sand and phosphorite, which together compose the sandstone aquifer, appear to be discontinuous; (3) the green clay unit of the Tamiami Formation contains large scale angular beds dipping eastward; and (4) numerous deeply cut alluvium-filled paleochannels underlie the Caloosahatchee River. (Woodard-USGS)
Rayleigh-wave dispersive energy imaging using a high-resolution linear radon transform
Luo, Y.; Xia, J.; Miller, R.D.; Xu, Y.; Liu, J.; Liu, Q.
2008-01-01
Multichannel Analysis of Surface Waves (MASW) analysis is an efficient tool to obtain the vertical shear-wave profile. One of the key steps in the MASW method is to generate an image of dispersive energy in the frequency-velocity domain, so dispersion curves can be determined by picking peaks of dispersion energy. In this paper, we propose to image Rayleigh-wave dispersive energy by high-resolution linear Radon transform (LRT). The shot gather is first transformed along the time direction to the frequency domain and then the Rayleigh-wave dispersive energy can be imaged by high-resolution LRT using a weighted preconditioned conjugate gradient algorithm. Synthetic data with a set of linear events are presented to show the process of generating dispersive energy. Results of synthetic and real-world examples demonstrate that, compared with the slant stacking algorithm, high-resolution LRT can improve the resolution of images of dispersion energy by more than 50%. ?? Birkhaueser 2008.
High-Resolution Remote Sensing Image Building Extraction Based on Markov Model
NASA Astrophysics Data System (ADS)
Zhao, W.; Yan, L.; Chang, Y.; Gong, L.
2018-04-01
With the increase of resolution, remote sensing images have the characteristics of increased information load, increased noise, more complex feature geometry and texture information, which makes the extraction of building information more difficult. To solve this problem, this paper designs a high resolution remote sensing image building extraction method based on Markov model. This method introduces Contourlet domain map clustering and Markov model, captures and enhances the contour and texture information of high-resolution remote sensing image features in multiple directions, and further designs the spectral feature index that can characterize "pseudo-buildings" in the building area. Through the multi-scale segmentation and extraction of image features, the fine extraction from the building area to the building is realized. Experiments show that this method can restrain the noise of high-resolution remote sensing images, reduce the interference of non-target ground texture information, and remove the shadow, vegetation and other pseudo-building information, compared with the traditional pixel-level image information extraction, better performance in building extraction precision, accuracy and completeness.
High-Resolution Electron Energy-Loss Spectroscopy (HREELS) Using a Monochromated TEM/STEM
NASA Technical Reports Server (NTRS)
Sai, Z. R.; Bradley, J. P.; Erni, R.; Browning, N.
2005-01-01
A 200 keV FEI TF20 XT monochromated (scanning) transmission electron microscope funded by NASA's SRLIDAP program is undergoing installation at Lawrence Livermore National Laboratory. Instrument specifications in STEM mode are Cs =1.0 mm, Cc =1.2 mm, image resolution =0.18 nm, and in TEM mode Cs =1.3 mm, Cc =1.3 mm, information limit =0.14 nm. Key features of the instrument are a voltage-stabilized high tension (HT) supply, a monochromator, a high-resolution electron energy-loss spectrometer/energy filter, a high-resolution annular darkfield detector, and a solid-state x-ray energy-dispersive spectrometer. The high-tension tank contains additional sections for 60Hz and high frequency filtering, resulting in an operating voltage of 200 kV plus or minus 0.005V, a greater than 10-fold improvement over earlier systems. The monochromator is a single Wien filter design. The energy filter is a Gatan model 866 Tridiem-ERS high resolution GIF spec d for less than or equal to 0.15 eV energy resolution with 29 pA of current in a 2 nm diameter probe. 0.13 eV has already been achieved during early installation. The x-ray detector (EDAX/Genesis 4000) has a take-off angle of 20 degrees, an active area of 30 square millimeters, and a solid angle of 0.3 steradians. The higher solid angle is possible because the objective pole-piece allows the detector to be positioned as close as 9.47 mm from the specimen. The voltage-stabilized HT supply, monochromator and GIF enable high-resolution electron energy-loss spectroscopy (HREELS) with energy resolution comparable to synchrotron XANES, but with approximately 100X better spatial resolution. The region between 0 and 100 eV is called the low-loss or valence electron energy-loss spectroscopy (VEELS) region where features due to collective plasma oscillations and single electron transitions of valence electrons are observed. Most of the low-loss VEELS features we are detecting are being observed for the first time in IDPs. A major focus of our research is to understand the origin and significance of these features and how they might be exploited to gain insight about IDPs and other meteoritic materials.
High-resolution scanning precession electron diffraction: Alignment and spatial resolution.
Barnard, Jonathan S; Johnstone, Duncan N; Midgley, Paul A
2017-03-01
Methods are presented for aligning the pivot point of a precessing electron probe in the scanning transmission electron microscope (STEM) and for assessing the spatial resolution in scanning precession electron diffraction (SPED) experiments. The alignment procedure is performed entirely in diffraction mode, minimising probe wander within the bright-field (BF) convergent beam electron diffraction (CBED) disk and is used to obtain high spatial resolution SPED maps. Through analysis of the power spectra of virtual bright-field images extracted from the SPED data, the precession-induced blur was measured as a function of precession angle. At low precession angles, SPED spatial resolution was limited by electronic noise in the scan coils; whereas at high precession angles SPED spatial resolution was limited by tilt-induced two-fold astigmatism caused by the positive spherical aberration of the probe-forming lens. Copyright © 2016 Elsevier B.V. All rights reserved.
High-resolution terahertz inline digital holography based on quantum cascade laser
NASA Astrophysics Data System (ADS)
Deng, Qinghua; Li, Weihua; Wang, Xuemin; Li, Zeyu; Huang, Haochong; Shen, Changle; Zhan, Zhiqiang; Zou, Ruijiao; Jiang, Tao; Wu, Weidong
2017-11-01
A key requirement to put terahertz (THz) imaging systems into applications is high resolution. Based on a self-developed THz quantum cascade laser (QCL), we demonstrate a THz inline digital holography imaging system with high lateral resolution. In our case, the lateral resolution of this holography imaging system is pushed to about 70 μm, which is close to the intrinsic resolution limit of this system. To the best of our knowledge, this is much smaller than what has been reported up to now. This is attributed to a series of improvements, such as shortening the QCL wavelength, increasing Nx and Ny by the synthetic aperture method, smoothing the source beam profile, and diminishing vibration due to the cryorefrigeration device. This kind of holography system with a resolution smaller than 100 μm opens the door for many imaging experiments. It will turn the THz imaging systems into applications.
High-resolution ab initio three-dimensional x-ray diffraction microscopy
Chapman, Henry N.; Barty, Anton; Marchesini, Stefano; ...
2006-01-01
Coherent x-ray diffraction microscopy is a method of imaging nonperiodic isolated objects at resolutions limited, in principle, by only the wavelength and largest scattering angles recorded. We demonstrate x-ray diffraction imaging with high resolution in all three dimensions, as determined by a quantitative analysis of the reconstructed volume images. These images are retrieved from the three-dimensional diffraction data using no a priori knowledge about the shape or composition of the object, which has never before been demonstrated on a nonperiodic object. We also construct two-dimensional images of thick objects with greatly increased depth of focus (without loss of transverse spatialmore » resolution). These methods can be used to image biological and materials science samples at high resolution with x-ray undulator radiation and establishes the techniques to be used in atomic-resolution ultrafast imaging at x-ray free-electron laser sources.« less
A flexible spatiotemporal method for fusing satellite images with different resolutions
Xiaolin Zhu; Eileen H. Helmer; Feng Gao; Desheng Liu; Jin Chen; Michael A. Lefsky
2016-01-01
Studies of land surface dynamics in heterogeneous landscapes often require remote sensing datawith high acquisition frequency and high spatial resolution. However, no single sensor meets this requirement. This study presents a new spatiotemporal data fusion method, the Flexible Spatiotemporal DAta Fusion (FSDAF) method, to generate synthesized frequent high spatial...
Decoding Overlapping Memories in the Medial Temporal Lobes Using High-Resolution fMRI
ERIC Educational Resources Information Center
Chadwick, Martin J.; Hassabis, Demis; Maguire, Eleanor A.
2011-01-01
The hippocampus is proposed to process overlapping episodes as discrete memory traces, although direct evidence for this in human episodic memory is scarce. Using green-screen technology we created four highly overlapping movies of everyday events. Participants were scanned using high-resolution fMRI while recalling the movies. Multivariate…
USDA-ARS?s Scientific Manuscript database
Genotyping by sequencing (GBS) provides opportunities to generate high-resolution genetic maps at a low per-sample genotyping cost, but missing data and under-calling of heterozygotes complicate the creation of GBS linkage maps for highly heterozygous species. To overcome these issues, we developed ...
There is a growing need in the field of exposure science for monitoring methods that rapidly screen environmental media for suspect contaminants. Measurement and analysis platforms, based on high resolution mass spectrometry (HRMS), now exist to meet this need. Here we describe r...
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hu, Jian Zhi; Rommereim, Donald N.; Wind, Robert A.
2006-11-01
A simple approach is reported that yields high resolution, high sensitivity ¹H NMR spectra of biofluids with limited mass supply. This is achieved by spinning a capillary sample tube containing a biofluid at the magic angle at a frequency of about 80Hz. A 2D pulse sequence called ¹H PASS is then used to produce a high-resolution ¹H NMR spectrum that is free from magnetic susceptibility induced line broadening. With this new approach a high resolution ¹H NMR spectrum of biofluids with a volume less than 1.0 µl can be easily achieved at a magnetic field strength as low as 7.05T.more » Furthermore, the methodology facilitates easy sample handling, i.e., the samples can be directly collected into inexpensive and disposable capillary tubes at the site of collection and subsequently used for NMR measurements. In addition, slow magic angle spinning improves magnetic field shimming and is especially suitable for high throughput investigations. In this paper first results are shown obtained in a magnetic field of 7.05T on urine samples collected from mice using a modified commercial NMR probe.« less
RBS/C, HRTEM and HRXRD study of damage accumulation in irradiated SrTiO3
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jagielski, Jacek; Jozwik, Przemyslaw A.; Jozwik Biala, Iwona
2013-05-14
Damage accumulation in argon-irradiated SrTiO3 single crystals has been studied by using combination of Rutherford Backscattering/Channeling (RBS/C), High Resolution Transmission Electron Microscopy (HRTEM) and High Resolution X-Ray Diffraction (HRXRD) techniques. The RBS/C spectra were fitted using McChasy, a Monte Carlo simulation code allowing the quantitative analysis of amorphous-like and dislocation-like types of defects. The results were interpreted by using a Multi-Step Damage Accumulation model which assumes, that the damage accumulation occurs in a series of structural transformations, the defect transformations are triggered by a stress caused by formation of a free volume in the irradiated crystal. This assumption has beenmore » confirmed by High Resolution Transmission Electron Microscopy and High Resolution X-Ray Diffraction analysis.« less
Sensitivity and resolution in frequency comb spectroscopy of buffer gas cooled polyatomic molecules
NASA Astrophysics Data System (ADS)
Changala, P. Bryan; Spaun, Ben; Patterson, David; Doyle, John M.; Ye, Jun
2016-12-01
We discuss the use of cavity-enhanced direct frequency comb spectroscopy in the mid-infrared region with buffer gas cooling of polyatomic molecules for high-precision rovibrational absorption spectroscopy. A frequency comb coupled to an optical enhancement cavity allows us to collect high-resolution, broad-bandwidth infrared spectra of translationally and rotationally cold (10-20 K) gas-phase molecules with high absorption sensitivity and fast acquisition times. The design and performance of the combined apparatus are discussed in detail. Recorded rovibrational spectra in the CH stretching region of several organic molecules, including vinyl bromide (CH_2CHBr), adamantane (C_{10}H_{16}), and diamantane (C_{14}H_{20}) demonstrate the resolution and sensitivity of this technique, as well as the intrinsic challenges faced in extending the frontier of high-resolution spectroscopy to large complex molecules.
New Release of the High-Resolution Mimas Atlas derived from Cassini-ISS Images
NASA Astrophysics Data System (ADS)
Roatsch, T.; Kersten, E.; Matz, K.-D.; Porco, C. C.
2017-09-01
The Cassini Imaging Science Subsystem (ISS) acquired 128 high-resolution images (< 1 km/pixel) of Mimas during its tour through the Saturnian system since 2004. We combined new images from orbit 249 (Nov. 2016) and orbit 259 (Jan. 2017) with the high-resolution global semi-controlled mosaic of Mimas from 2012. This global mosaic is the baseline for the new high-resolution Mimas atlas that still consists of three tiles mapped at a scale of 1:1,000,000 [1]. The nomenclature used in this atlas was proposed by the Cassini imaging team and was approved by the International Astronomical Union (IAU). The entire atlas will become available to the public through the Imaging Team's website [http://ciclops.org/maps] and the Planetary Data System (PDS) [https://pds- imaging.jpl.nasa.gov/volumes/carto.html].
High Resolution Rapid Revisits Insar Monitoring of Surface Deformation
NASA Astrophysics Data System (ADS)
Singhroy, V.; Li, J.; Charbonneau, F.
2014-12-01
Monitoring surface deformation on strategic energy and transportation corridors requires high resolution spatial and temporal InSAR images for mitigation and safety purposes. High resolution air photos, lidar and other satellite images are very useful in areas where the landslides can be fatal. Recently, radar interferometry (InSAR) techniques using more rapid revisit images from several radar satellites are increasingly being used in active deformation monitoring. The Canadian RADARSAT Constellation (RCM) is a three-satellite mission that will provide rapid revisits of four days interferometric (InSAR) capabilities that will be very useful for complex deformation monitoring. For instance, the monitoring of surface deformation due to permafrost activity, complex rock slide motion and steam assisted oil extraction will benefit from this new rapid revisit capability. This paper provide examples of how the high resolution (1-3 m) rapid revisit InSAR capabilities will improve our monitoring of surface deformation and provide insights in understanding triggering mechanisms. We analysed over a hundred high resolution InSAR images over a two year period on three geologically different sites with various configurations of topography, geomorphology, and geology conditions. We show from our analysis that the more frequent InSAR acquisitions are providing more information in understanding the rates of movement and failure process of permafrost triggered retrogressive thaw flows; the complex motion of an asymmetrical wedge failure of an active rock slide and the identification of over pressure zones related to oil extraction using steam injection. Keywords: High resolution, InSAR, rapid revisits, triggering mechanisms, oil extraction.
High-sensitivity Leak-testing Method with High-Resolution Integration Technique
NASA Astrophysics Data System (ADS)
Fujiyoshi, Motohiro; Nonomura, Yutaka; Senda, Hidemi
A high-resolution leak-testing method named HR (High-Resolution) Integration Technique has been developed for MEMS (Micro Electro Mechanical Systems) sensors such as a vibrating angular-rate sensor housed in a vacuum package. Procedures of the method to obtain high leak-rate resolution were as follows. A package filled with helium gas was kept in a small accumulation chamber to accumulate helium gas leaking from the package. After the accumulation, the accumulated helium gas was introduced into a mass spectrometer in a short period of time, and the flux of the helium gas was measured by the mass spectrometer as a transient phenomenon. The leak-rate of the package was calculated from the detected transient waveform of the mass spectrometer and the accumulation time of the helium gas in the accumulation chamber. Because the density of the helium gas in the vacuum chamber increased and the accumulated helium gas was measured in a very short period of time with the mass spectrometer, the peak strength of the transient waveform became high and the signal to noise ratio was much improved. The detectable leak-rate resolution of the technique reached 1×10-15 (Pa·m3/s). This resolution is 103 times superior to that of the conventional helium vacuum integration method. The accuracy of the measuring system was verified with a standard helium gas leak source. The results were well matched between theoretical calculation based on the leak-rate of the source and the experimental results within only 2% error.
High-Resolution Global Soil Moisture Map
2015-05-19
High-resolution global soil moisture map from NASA SMAP combined radar and radiometer instruments, acquired between May 4 and May 11, 2015 during SMAP commissioning phase. The map has a resolution of 5.6 miles (9 kilometers). The data gap is due to turning the instruments on and off during testing. http://photojournal.jpl.nasa.gov/catalog/PIA19337
USDA-ARS?s Scientific Manuscript database
High resolution x-ray computed tomography (HRCT) is a non-destructive diagnostic imaging technique with sub-micron resolution capability that is now being used to evaluate the structure and function of plant xylem network in three dimensions (3D). HRCT imaging is based on the same principles as medi...
High energy near- and far-field ptychographic tomography at the ESRF
NASA Astrophysics Data System (ADS)
da Silva, Julio C.; Haubrich, Jan; Requena, Guillermo; Hubert, Maxime; Pacureanu, Alexandra; Bloch, Leonid; Yang, Yang; Cloetens, Peter
2017-09-01
In high-resolution tomography, one needs high-resolved projections in order to reconstruct a high-quality 3D map of a sample. X-ray ptychography is a robust technique which can provide such high-resolution 2D projections taking advantage of coherent X-rays. This technique was used in the far-field regime for a fair amount of time, but it can now also be implemented in the near-field regime. In both regimes, the technique enables not only high-resolution imaging, but also high sensitivity to the electron density of the sample. The combination with tomography makes 3D imaging possible via ptychographic X-ray computed tomography (PXCT), which can provide a 3D map of the complex-valued refractive index of the sample. The extension of PXCT to X-ray energies above 15 keV is challenging, but it can allow the imaging of object opaque to lower energy. We present here the implementation and developments of high-energy near- and far-field PXCT at the ESRF.
Study on a High Compression Processing for Video-on-Demand e-learning System
NASA Astrophysics Data System (ADS)
Nomura, Yoshihiko; Matsuda, Ryutaro; Sakamoto, Ryota; Sugiura, Tokuhiro; Matsui, Hirokazu; Kato, Norihiko
The authors proposed a high-quality and small-capacity lecture-video-file creating system for distance e-learning system. Examining the feature of the lecturing scene, the authors ingeniously employ two kinds of image-capturing equipment having complementary characteristics : one is a digital video camera with a low resolution and a high frame rate, and the other is a digital still camera with a high resolution and a very low frame rate. By managing the two kinds of image-capturing equipment, and by integrating them with image processing, we can produce course materials with the greatly reduced file capacity : the course materials satisfy the requirements both for the temporal resolution to see the lecturer's point-indicating actions and for the high spatial resolution to read the small written letters. As a result of a comparative experiment, the e-lecture using the proposed system was confirmed to be more effective than an ordinary lecture from the viewpoint of educational effect.
Damage extraction of buildings in the 2015 Gorkha, Nepal earthquake from high-resolution SAR data
NASA Astrophysics Data System (ADS)
Yamazaki, Fumio; Bahri, Rendy; Liu, Wen; Sasagawa, Tadashi
2016-05-01
Satellite remote sensing is recognized as one of the effective tools for detecting and monitoring affected areas due to natural disasters. Since SAR sensors can capture images not only at daytime but also at nighttime and under cloud-cover conditions, they are especially useful at an emergency response period. In this study, multi-temporal high-resolution TerraSAR-X images were used for damage inspection of the Kathmandu area, which was severely affected by the April 25, 2015 Gorkha Earthquake. The SAR images obtained before and after the earthquake were utilized for calculating the difference and correlation coefficient of backscatter. The affected areas were identified by high values of the absolute difference and low values of the correlation coefficient. The post-event high-resolution optical satellite images were employed as ground truth data to verify our results. Although it was difficult to estimate the damage levels for individual buildings, the high resolution SAR images could illustrate their capability in detecting collapsed buildings at emergency response times.
High-Speed and Scalable Whole-Brain Imaging in Rodents and Primates.
Seiriki, Kaoru; Kasai, Atsushi; Hashimoto, Takeshi; Schulze, Wiebke; Niu, Misaki; Yamaguchi, Shun; Nakazawa, Takanobu; Inoue, Ken-Ichi; Uezono, Shiori; Takada, Masahiko; Naka, Yuichiro; Igarashi, Hisato; Tanuma, Masato; Waschek, James A; Ago, Yukio; Tanaka, Kenji F; Hayata-Takano, Atsuko; Nagayasu, Kazuki; Shintani, Norihito; Hashimoto, Ryota; Kunii, Yasuto; Hino, Mizuki; Matsumoto, Junya; Yabe, Hirooki; Nagai, Takeharu; Fujita, Katsumasa; Matsuda, Toshio; Takuma, Kazuhiro; Baba, Akemichi; Hashimoto, Hitoshi
2017-06-21
Subcellular resolution imaging of the whole brain and subsequent image analysis are prerequisites for understanding anatomical and functional brain networks. Here, we have developed a very high-speed serial-sectioning imaging system named FAST (block-face serial microscopy tomography), which acquires high-resolution images of a whole mouse brain in a speed range comparable to that of light-sheet fluorescence microscopy. FAST enables complete visualization of the brain at a resolution sufficient to resolve all cells and their subcellular structures. FAST renders unbiased quantitative group comparisons of normal and disease model brain cells for the whole brain at a high spatial resolution. Furthermore, FAST is highly scalable to non-human primate brains and human postmortem brain tissues, and can visualize neuronal projections in a whole adult marmoset brain. Thus, FAST provides new opportunities for global approaches that will allow for a better understanding of brain systems in multiple animal models and in human diseases. Copyright © 2017 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Neukum, Gerhard; Jaumann, Ralf; Scholten, Frank; Gwinner, Klaus
2017-11-01
At the Institute of Space Sensor Technology and Planetary Exploration of the German Aerospace Center (DLR) the High Resolution Stereo Camera (HRSC) has been designed for international missions to planet Mars. For more than three years an airborne version of this camera, the HRSC-A, has been successfully applied in many flight campaigns and in a variety of different applications. It combines 3D-capabilities and high resolution with multispectral data acquisition. Variable resolutions depending on the camera control settings can be generated. A high-end GPS/INS system in combination with the multi-angle image information yields precise and high-frequent orientation data for the acquired image lines. In order to handle these data a completely automated photogrammetric processing system has been developed, and allows to generate multispectral 3D-image products for large areas and with accuracies for planimetry and height in the decimeter range. This accuracy has been confirmed by detailed investigations.
Radiometric infrared focal plane array imaging system for thermographic applications
NASA Technical Reports Server (NTRS)
Esposito, B. J.; Mccafferty, N.; Brown, R.; Tower, J. R.; Kosonocky, W. F.
1992-01-01
This document describes research performed under the Radiometric Infrared Focal Plane Array Imaging System for Thermographic Applications contract. This research investigated the feasibility of using platinum silicide (PtSi) Schottky-barrier infrared focal plane arrays (IR FPAs) for NASA Langley's specific radiometric thermal imaging requirements. The initial goal of this design was to develop a high spatial resolution radiometer with an NETD of 1 percent of the temperature reading over the range of 0 to 250 C. The proposed camera design developed during this study and described in this report provides: (1) high spatial resolution (full-TV resolution); (2) high thermal dynamic range (0 to 250 C); (3) the ability to image rapid, large thermal transients utilizing electronic exposure control (commandable dynamic range of 2,500,000:1 with exposure control latency of 33 ms); (4) high uniformity (0.5 percent nonuniformity after correction); and (5) high thermal resolution (0.1 C at 25 C background and 0.5 C at 250 C background).
Application of high resolution synchrotron micro-CT radiation in dental implant osseointegration.
Neldam, Camilla Albeck; Lauridsen, Torsten; Rack, Alexander; Lefolii, Tore Tranberg; Jørgensen, Niklas Rye; Feidenhans'l, Robert; Pinholt, Else Marie
2015-06-01
The purpose of this study was to describe a refined method using high-resolution synchrotron radiation microtomography (SRmicro-CT) to evaluate osseointegration and peri-implant bone volume fraction after titanium dental implant insertion. SRmicro-CT is considered gold standard evaluating bone microarchitecture. Its high resolution, high contrast, and excellent high signal-to-noise-ratio all contribute to the highest spatial resolutions achievable today. Using SRmicro-CT at a voxel size of 5 μm in an experimental goat mandible model, the peri-implant bone volume fraction was found to quickly increase to 50% as the radial distance from the implant surface increased, and levelled out to approximately 80% at a distance of 400 μm. This method has been successful in depicting the bone and cavities in three dimensions thereby enabling us to give a more precise answer to the fraction of the bone-to-implant contact compared to previous methods. Copyright © 2015 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
Radiometric infrared focal plane array imaging system for thermographic applications
NASA Astrophysics Data System (ADS)
Esposito, B. J.; McCafferty, N.; Brown, R.; Tower, J. R.; Kosonocky, W. F.
1992-11-01
This document describes research performed under the Radiometric Infrared Focal Plane Array Imaging System for Thermographic Applications contract. This research investigated the feasibility of using platinum silicide (PtSi) Schottky-barrier infrared focal plane arrays (IR FPAs) for NASA Langley's specific radiometric thermal imaging requirements. The initial goal of this design was to develop a high spatial resolution radiometer with an NETD of 1 percent of the temperature reading over the range of 0 to 250 C. The proposed camera design developed during this study and described in this report provides: (1) high spatial resolution (full-TV resolution); (2) high thermal dynamic range (0 to 250 C); (3) the ability to image rapid, large thermal transients utilizing electronic exposure control (commandable dynamic range of 2,500,000:1 with exposure control latency of 33 ms); (4) high uniformity (0.5 percent nonuniformity after correction); and (5) high thermal resolution (0.1 C at 25 C background and 0.5 C at 250 C background).
High-resolution Interferometer Sounder (HIS), phase 2
NASA Technical Reports Server (NTRS)
1988-01-01
The High-resolution Interferometer Sounder (HIS) was successfully built, tested, and flight proven on the NASA U-2/ER-2 high altitude aircraft. The HIS demonstration has shown that, by using the technology of Fourier Transform Spectroscopy (FTS), it is possible to measure the spectrum of upwelling infrared radiance needed for temperature and humidity sounding with high spectral resolution and high radiometric precision. By resolving individual carbon dioxide lines, the retrieved temperature profiles have vertical resolutions of 1 to 2 km and RMS errors less than 1 C, about 2 to 4 times better than possible with current sounders. Implementing this capability on satellite sounders will greatly enhance the dynamical information content of temperature measurements from space. The aircraft model HIS is now a resource which should be used to support field experiments in mesoscale meteorology, to monitor trace gas concentrations and to better understand their effects on climate, to monitor the surface radiation budget and the radiative effects of clouds, and to collect data for research into retrieval techniques, especially under partially cloudy conditions.
High Resolution Model Intercomparison Project (HighResMIP v1.0) for CMIP6
Haarsma, Reindert J.; Roberts, Malcolm J.; Vidale, Pier Luigi; ...
2016-11-22
Robust projections and predictions of climate variability and change, particularly at regional scales, rely on the driving processes being represented with fidelity in model simulations. The role of enhanced horizontal resolution in improved process representation in all components of the climate system is of growing interest, particularly as some recent simulations suggest both the possibility of significant changes in large-scale aspects of circulation as well as improvements in small-scale processes and extremes. However, such high-resolution global simulations at climate timescales, with resolutions of at least 50 km in the atmosphere and 0.25° in the ocean, have been performed at relativelymore » few research centres and generally without overall coordination, primarily due to their computational cost. Assessing the robustness of the response of simulated climate to model resolution requires a large multi-model ensemble using a coordinated set of experiments. The Coupled Model Intercomparison Project 6 (CMIP6) is the ideal framework within which to conduct such a study, due to the strong link to models being developed for the CMIP DECK experiments and other model intercomparison projects (MIPs). Increases in high-performance computing (HPC) resources, as well as the revised experimental design for CMIP6, now enable a detailed investigation of the impact of increased resolution up to synoptic weather scales on the simulated mean climate and its variability. The High Resolution Model Intercomparison Project (HighResMIP) presented in this paper applies, for the first time, a multi-model approach to the systematic investigation of the impact of horizontal resolution. A coordinated set of experiments has been designed to assess both a standard and an enhanced horizontal-resolution simulation in the atmosphere and ocean. The set of HighResMIP experiments is divided into three tiers consisting of atmosphere-only and coupled runs and spanning the period 1950–2050, with the possibility of extending to 2100, together with some additional targeted experiments. This paper describes the experimental set-up of HighResMIP, the analysis plan, the connection with the other CMIP6 endorsed MIPs, as well as the DECK and CMIP6 historical simulations. Lastly, HighResMIP thereby focuses on one of the CMIP6 broad questions, “what are the origins and consequences of systematic model biases?”, but we also discuss how it addresses the World Climate Research Program (WCRP) grand challenges.« less
Masoudi, Ali; Newson, Trevor P
2017-01-15
A distributed optical fiber dynamic strain sensor with high spatial and frequency resolution is demonstrated. The sensor, which uses the ϕ-OTDR interrogation technique, exhibited a higher sensitivity thanks to an improved optical arrangement and a new signal processing procedure. The proposed sensing system is capable of fully quantifying multiple dynamic perturbations along a 5 km long sensing fiber with a frequency and spatial resolution of 5 Hz and 50 cm, respectively. The strain resolution of the sensor was measured to be 40 nε.
Rauniyar, Navin
2015-01-01
The parallel reaction monitoring (PRM) assay has emerged as an alternative method of targeted quantification. The PRM assay is performed in a high resolution and high mass accuracy mode on a mass spectrometer. This review presents the features that make PRM a highly specific and selective method for targeted quantification using quadrupole-Orbitrap hybrid instruments. In addition, this review discusses the label-based and label-free methods of quantification that can be performed with the targeted approach. PMID:26633379
High resolution modelling and observation of wind-driven surface currents in a semi-enclosed estuary
NASA Astrophysics Data System (ADS)
Nash, S.; Hartnett, M.; McKinstry, A.; Ragnoli, E.; Nagle, D.
2012-04-01
Hydrodynamic circulation in estuaries is primarily driven by tides, river inflows and surface winds. While tidal and river data can be quite easily obtained for input to hydrodynamic models, sourcing accurate surface wind data is problematic. Firstly, the wind data used in hydrodynamic models is usually measured on land and can be quite different in magnitude and direction from offshore winds. Secondly, surface winds are spatially-varying but due to a lack of data it is common practice to specify a non-varying wind speed and direction across the full extents of a model domain. These problems can lead to inaccuracies in the surface currents computed by three-dimensional hydrodynamic models. In the present research, a wind forecast model is coupled with a three-dimensional numerical model of Galway Bay, a semi-enclosed estuary on the west coast of Ireland, to investigate the effect of surface wind data resolution on model accuracy. High resolution and low resolution wind fields are specified to the model and the computed surface currents are compared with high resolution surface current measurements obtained from two high frequency SeaSonde-type Coastal Ocean Dynamics Applications Radars (CODAR). The wind forecast models used for the research are Harmonie cy361.3, running on 2.5 and 0.5km spatial grids for the low resolution and high resolution models respectively. The low-resolution model runs over an Irish domain on 540x500 grid points with 60 vertical levels and a 60s timestep and is driven by ECMWF boundary conditions. The nested high-resolution model uses 300x300 grid points on 60 vertical levels and a 12s timestep. EFDC (Environmental Fluid Dynamics Code) is used for the hydrodynamic model. The Galway Bay model has ten vertical layers and is resolved spatially and temporally at 150m and 4 sec respectively. The hydrodynamic model is run for selected hindcast dates when wind fields were highly energetic. Spatially- and temporally-varying wind data is provided by offline coupling with the wind forecast models. Modelled surface currents show good correlation with CODAR observed currents and the resolution of the surface wind data is shown to be important for model accuracy.
High resolution estimates of the corrosion risk for cultural heritage in Italy.
De Marco, Alessandra; Screpanti, Augusto; Mircea, Mihaela; Piersanti, Antonio; Proietti, Chiara; Fornasier, M Francesca
2017-07-01
Air pollution plays a pivotal role in the deterioration of many materials used in buildings and cultural monuments causing an inestimable damage. This study aims to estimate the impacts of air pollution (SO 2 , HNO 3 , O 3 , PM 10 ) and meteorological conditions (temperature, precipitation, relative humidity) on limestone, copper and bronze based on high resolution air quality data-base produced with AMS-MINNI modelling system over the Italian territory over the time period 2003-2010. A comparison between high resolution data (AMS-MINNI grid, 4 × 4 km) and low resolution data (EMEP grid, 50 × 50 km) has been performed. Our results pointed out that the corrosion levels for limestone, copper and bronze are decreased in Italy from 2003 to 2010 in relation to decrease of pollutant concentrations. However, some problem related to air pollution persists especially in Northern and Southern Italy. In particular, PM 10 and HNO 3 are considered the main responsible for limestone corrosion. Moreover, the high resolution data (AMS-MINNI) allowed the identification of risk areas that are not visible with the low resolution data (EMEP modelling system) in all considered years and, especially, in the limestone case. Consequently, high resolution air quality simulations are suitable to provide concrete benefits in providing information for national effective policy against corrosion risk for cultural heritage, also in the context of climate changes that are affecting strongly Mediterranean basin. Copyright © 2017 Elsevier Ltd. All rights reserved.
[Polymorphism of HLA-B* 40 gene family in Chinese Han population].
Li, Zhen; Jin, Shi-Zheng; Cheng, Liang-Hong; Wang, Da-Ming; Zhou, Dan; Zou, Hong-Yan; Wu, Guo-Guang
2005-04-01
To investigate the allele distribution of HLA-B* 40 gene family in Chinese Han population and to study its influence on the selection of clinical transplantation donor, the HLA-B genetypes of 381 individuals randomly selected from Chinese National Marrow Donor Project were identified by PCR-SSO, and then all the HLA-B* 40 positive samples from the above population and the B* 40 homozygote samples received from another 1 270 registered donors were analyzed by PCR-SBT and PCR-SSP at high resolution. The results showed that the population of 381 registered donors was examined at HLA-B locus by using Hardy-Weinberg equilibrium, the gene frequency of HLA-B* 40 was 0.1692. Four different HLA-B* 40 alleles (B* 4001, B* 4002, B* 4003, B* 4006) were identified, and the serological specificity was B60 and B61 respectively. The relative frequency of each allele was 0.1192 for B* 4001, 0.0154 for B* 4002, 0.0038 for B* 4003, 0.0308 for B* 4006. The distribution of B* 40 homozygote revealed a certain regularity at high-resolution, B* 40XX (B* 4001 group), at low-resolution; B* 4001 at high resolution; B* 40XX (B* 4002 group), at low-resolution; B* 4002 or B* 4006 or heterozygote of both at high-resolution. It is concluded that in Chinese Han population, predominant allele in HLA-B* 40 gene family is B* 4001, the high-resolution typing may be recommended to use for the selection of clinical transplantation donor.
Chung, Euiheon; Kim, Daekeun; Cui, Yan; Kim, Yang-Hyo; So, Peter T. C.
2007-01-01
The development of high resolution, high speed imaging techniques allows the study of dynamical processes in biological systems. Lateral resolution improvement of up to a factor of 2 has been achieved using structured illumination. In a total internal reflection fluorescence microscope, an evanescence excitation field is formed as light is total internally reflected at an interface between a high and a low index medium. The <100 nm penetration depth of evanescence field ensures a thin excitation region resulting in low background fluorescence. We present even higher resolution wide-field biological imaging by use of standing wave total internal reflection fluorescence (SW-TIRF). Evanescent standing wave (SW) illumination is used to generate a sinusoidal high spatial frequency fringe pattern on specimen for lateral resolution enhancement. To prevent thermal drift of the SW, novel detection and estimation of the SW phase with real-time feedback control is devised for the stabilization and control of the fringe phase. SW-TIRF is a wide-field superresolution technique with resolution better than a fifth of emission wavelength or ∼100 nm lateral resolution. We demonstrate the performance of the SW-TIRF microscopy using one- and two-directional SW illumination with a biological sample of cellular actin cytoskeleton of mouse fibroblast cells as well as single semiconductor nanocrystal molecules. The results confirm the superior resolution of SW-TIRF in addition to the merit of a high signal/background ratio from TIRF microscopy. PMID:17483188
NASA Astrophysics Data System (ADS)
McAlister, Harold A.
1992-11-01
The Center for High Angular Resolution Astronomy (CHARA) was established in the College of Arts and Sciences at Georgia State University in 1984 with the goals of designing, constructing, and then operating a facility for very high spatial resolution astronomy. The interest in such a facility grew out of the participants' decade of activity in speckle interferometry. Although speckle interferometry continues to provide important astrophysical measurements of a variety of objects, many pressing problems require resolution far beyond that which can be expected from single aperture telescopes. In early 1986, CHARA received a grant from the National Science Foundation which has permitted a detailed exploration of the feasibility of constructing a facility which will provide a hundred-fold increase in angular resolution over what is possible by speckle interferometry at the largest existing telescopes. The design concept for the CHARA Array was developed initially with the contractural collaboration of United Technologies Optical Systems, Inc., in West Palm Beach, Florida, an arrangement that expired in August 1987. In late November 1987, the Georgia Tech Research Institute joined with CHARA to continue and complete the design concept study. Very high-resolution imaging at optical wavelengths is clearly coming of age in astronomy. The CHARA Array and other related projects will be important and necessary milestones along the way toward the development of a major national facility for high-resolution imaging--a true optical counterpart to the Very Large Array. Ground-based arrays and their scientific output will lead to high resolution facilities in space and, ultimately, on the Moon.
Flexible high-resolution display systems for the next generation of radiology reading rooms
NASA Astrophysics Data System (ADS)
Caban, Jesus J.; Wood, Bradford J.; Park, Adrian
2007-03-01
A flexible, scalable, high-resolution display system is presented to support the next generation of radiology reading rooms or interventional radiology suites. The project aims to create an environment for radiologists that will simultaneously facilitate image interpretation, analysis, and understanding while lowering visual and cognitive stress. Displays currently in use present radiologists with technical challenges to exploring complex datasets that we seek to address. These include resolution and brightness, display and ambient lighting differences, and degrees of complexity in addition to side-by-side comparison of time-variant and 2D/3D images. We address these issues through a scalable projector-based system that uses our custom-designed geometrical and photometrical calibration process to create a seamless, bright, high-resolution display environment that can reduce the visual fatigue commonly experienced by radiologists. The system we have designed uses an array of casually aligned projectors to cooperatively increase overall resolution and brightness. Images from a set of projectors in their narrowest zoom are combined at a shared projection surface, thus increasing the global "pixels per inch" (PPI) of the display environment. Two primary challenges - geometric calibration and photometric calibration - remained to be resolved before our high-resolution display system could be used in a radiology reading room or procedure suite. In this paper we present a method that accomplishes those calibrations and creates a flexible high-resolution display environment that appears seamless, sharp, and uniform across different devices.
Developmental approach towards high resolution optical coherence tomography for glaucoma diagnostics
NASA Astrophysics Data System (ADS)
Kemper, Björn; Ketelhut, Steffi; Heiduschka, Peter; Thorn, Marie; Larsen, Michael; Schnekenburger, Jürgen
2018-02-01
Glaucoma is caused by a pathological rise in the intraocular pressure, which results in a progressive loss of vision by a damage to retinal cells and the optical nerve head. Early detection of pressure-induced damage is thus essential for the reduction of eye pressure and to prevent severe incapacity or blindness. Within the new European Project GALAHAD (Glaucoma Advanced, Label free High Resolution Automated OCT Diagnostics), we will develop a new low-cost and high-resolution OCT system for the early detection of glaucoma. The device is designed to improve diagnosis based on a new system of optical coherence tomography. Although OCT systems are at present available in ophthalmology centres, high-resolution devices are extremely expensive. The novelty of the new Galahad system is its super wideband light source to achieve high image resolution at a reasonable cost. Proof of concept experiments with cell and tissue Glaucoma test standards and animal models are planned for the test of the new optical components and new algorithms performance for the identification of Glaucoma associated cell and tissue structures. The intense training of the software systems with various samples should result in a increased sensitivity and specificity of the OCT software system.
Zhang, Yong-Tao; Shi, Jing; Shu, Chi-Wang; Zhou, Ye
2003-10-01
A quantitative study is carried out in this paper to investigate the size of numerical viscosities and the resolution power of high-order weighted essentially nonoscillatory (WENO) schemes for solving one- and two-dimensional Navier-Stokes equations for compressible gas dynamics with high Reynolds numbers. A one-dimensional shock tube problem, a one-dimensional example with parameters motivated by supernova and laser experiments, and a two-dimensional Rayleigh-Taylor instability problem are used as numerical test problems. For the two-dimensional Rayleigh-Taylor instability problem, or similar problems with small-scale structures, the details of the small structures are determined by the physical viscosity (therefore, the Reynolds number) in the Navier-Stokes equations. Thus, to obtain faithful resolution to these small-scale structures, the numerical viscosity inherent in the scheme must be small enough so that the physical viscosity dominates. A careful mesh refinement study is performed to capture the threshold mesh for full resolution, for specific Reynolds numbers, when WENO schemes of different orders of accuracy are used. It is demonstrated that high-order WENO schemes are more CPU time efficient to reach the same resolution, both for the one-dimensional and two-dimensional test problems.
Larue, Michelle A; Knight, Joseph
2014-12-01
The Southern Ocean is one of the most rapidly changing ecosystems on the planet due to the effects of climate change and commercial fishing for ecologically important krill and fish. Because sea ice loss is expected to be accompanied by declines in krill and fish predators, decoupling the effects of climate and anthropogenic changes on these predator populations is crucial for ecosystem-based management of the Southern Ocean. We reviewed research published from 2007 to 2014 that incorporated very high-resolution satellite imagery to assess distribution, abundance, and effects of climate and other anthropogenic changes on populations of predators in polar regions. Very high-resolution imagery has been used to study 7 species of polar animals in 13 papers, many of which provide methods through which further research can be conducted. Use of very high-resolution imagery in the Southern Ocean can provide a broader understanding of climate and anthropogenic forces on populations and inform management and conservation recommendations. We recommend that conservation biologists continue to integrate high-resolution remote sensing into broad-scale biodiversity and population studies in remote areas, where it can provide much needed detail. © 2014 Society for Conservation Biology.
First light of the CHARIS high-contrast integral-field spectrograph
NASA Astrophysics Data System (ADS)
Groff, Tyler; Chilcote, Jeffrey; Brandt, Timothy; Kasdin, N. Jeremy; Galvin, Michael; Loomis, Craig; Rizzo, Maxime; Knapp, Gillian; Guyon, Olivier; Jovanovic, Nemanja; Lozi, Julien; Currie, Thayne; Takato, Naruhisa; Hayashi, Masahiko
2017-09-01
One of the leading direct Imaging techniques, particularly in ground-based imaging, uses a coronagraphic system and integral field spectrograph (IFS). The Coronagraphic High Angular Resolution Imaging Spectrograph (CHARIS) is an IFS that has been built for the Subaru telescope. CHARIS has been delivered to the observatory and now sits behind the Subaru Coronagraphic Extreme Adaptive Optics (SCExAO) system. CHARIS has `high' and `low' resolution operating modes. The high-resolution mode is used to characterize targets in J, H, and K bands at R70. The low-resolution prism is meant for discovery and spans J+H+K bands (1.15-2.37 microns) with a spectral resolution of R18. This discovery mode has already proven better than 15-sigma detections of HR8799c,d,e when combining ADI+SDI. Using SDI alone, planets c and d have been detected in a single 24 second image. The CHARIS team is optimizing instrument performance and refining ADI+SDI recombination to maximize our contrast detection limit. In addition to the new observing modes, CHARIS has demonstrated a design with high robustness to spectral crosstalk. CHARIS has completed commissioning and is open for science observations.
NASA Astrophysics Data System (ADS)
Pandiyan, Vimal Prabhu; Khare, Kedar; John, Renu
2017-09-01
A constrained optimization approach with faster convergence is proposed to recover the complex object field from a near on-axis digital holography (DH). We subtract the DC from the hologram after recording the object beam and reference beam intensities separately. The DC-subtracted hologram is used to recover the complex object information using a constrained optimization approach with faster convergence. The recovered complex object field is back propagated to the image plane using the Fresnel back-propagation method. The results reported in this approach provide high-resolution images compared with the conventional Fourier filtering approach and is 25% faster than the previously reported constrained optimization approach due to the subtraction of two DC terms in the cost function. We report this approach in DH and digital holographic microscopy using the U.S. Air Force resolution target as the object to retrieve the high-resolution image without DC and twin image interference. We also demonstrate the high potential of this technique in transparent microelectrode patterned on indium tin oxide-coated glass, by reconstructing a high-resolution quantitative phase microscope image. We also demonstrate this technique by imaging yeast cells.
Final Report: High Spectral Resolution Atmospheric Emitted Radiance Studies with the ARM UAV
DOE Office of Scientific and Technical Information (OSTI.GOV)
Revercomb, Henry E.
1999-12-31
The active participation in the Atmospheric Radiation Measurement (ARM) Unmanned Airborne Vehicle (UAV) science team that was anticipated in the grant proposal was indefinitely delayed after the first year due to a programmatic decision to exclude the high spectral resolution observations from the existing ARM UAV program. However, this report shows that substantial progress toward the science objectives of this grant have made with the help of separate funding from NASA and other agencies. In the four year grant period (including time extensions), a new high spectral resolution instrument has been flown and has successfully demonstrated the ability to obtainmore » measurements of the type needed in the conduct of this grant. In the near term, the third water vapor intensive observing period (WVIOP-3) in October 2000 will provide an opportunity to bring the high spectral resolution observations of upwelling radiance into the ARM program to complement the downwelling radiance observations from the existing ARM AERI instruments. We look forward to a time when the ARM-UAV program is able to extend its scope to include the capability for making these high spectral resolution measurements from a UAV platform.« less
Akten, H Serpil; Kilic, Hatice; Celik, Bulent; Erbas, Gonca; Isikdogan, Zeynep; Turktas, Haluk; Kokturk, Nurdan
2018-04-25
This study aimed to evaluate the diagnostic yield of fiberoptic bronchoscopic (FOB) transbronchial biopsy and its relation with quantitative findings of high resolution computerized tomography (HRCT). A total of 83 patients, 19 males and 64 females with a mean age of 45.1 years diagnosed with sarcoidosis with complete records of high resolution computerized tomography were retrospectively recruited during the time period from Feb 2005 to Jan 2015. High resolution computerized tomography scans were retrospectively assessed in random order by an experienced observer without knowledge of the bronchoscopic results or lung function tests. According to the radiological staging with HRCT, 2.4% of the patients (n=2) were stage 0, 19.3% (n=16) were stage 1, 72.3% (n=60) were stage 2 and 6.0% (n=5) were stage 3. This study showed that transbronchial lung biopsy showed positive results in 39.7% of the stage I or II sarcoidosis patients who were diagnosed by bronchoscopy. Different high resolution computerized tomography patterns and different scores of involvement did make a difference in the diagnostic accuracy of transbronchial biopsy (p=0.007). Creative Commons Attribution License
Semi-automatic mapping of linear-trending bedforms using 'Self-Organizing Maps' algorithm
NASA Astrophysics Data System (ADS)
Foroutan, M.; Zimbelman, J. R.
2017-09-01
Increased application of high resolution spatial data such as high resolution satellite or Unmanned Aerial Vehicle (UAV) images from Earth, as well as High Resolution Imaging Science Experiment (HiRISE) images from Mars, makes it necessary to increase automation techniques capable of extracting detailed geomorphologic elements from such large data sets. Model validation by repeated images in environmental management studies such as climate-related changes as well as increasing access to high-resolution satellite images underline the demand for detailed automatic image-processing techniques in remote sensing. This study presents a methodology based on an unsupervised Artificial Neural Network (ANN) algorithm, known as Self Organizing Maps (SOM), to achieve the semi-automatic extraction of linear features with small footprints on satellite images. SOM is based on competitive learning and is efficient for handling huge data sets. We applied the SOM algorithm to high resolution satellite images of Earth and Mars (Quickbird, Worldview and HiRISE) in order to facilitate and speed up image analysis along with the improvement of the accuracy of results. About 98% overall accuracy and 0.001 quantization error in the recognition of small linear-trending bedforms demonstrate a promising framework.
High-resolution imaging of silicene on an Ag(111) surface by atomic force microscopy
NASA Astrophysics Data System (ADS)
Onoda, Jo; Yabuoshi, Keisuke; Miyazaki, Hiroki; Sugimoto, Yoshiaki
2017-12-01
Silicene, a two-dimensional (2D) honeycomb arrangement of Si atoms, is expected to have better electronic properties than graphene and has been mostly synthesized on Ag surfaces. Although scanning tunneling microscopy (STM) has been used for visualizing its atomic structure in real space, the interpretation of STM contrast is not straightforward and only the topmost Si atoms were observed on the (4 ×4 ) silicene/Ag(111) surface. Here, we demonstrate that high-resolution atomic force microscopy (AFM) can resolve all constituent Si atoms in the buckled honeycomb arrangement of the (4 ×4 ) silicene. Site-specific force spectroscopy attributes the origin of the high-resolution AFM images to chemical bonds between the AFM probe apex and the individual Si atoms on the (4 ×4 ) silicene. A detailed analysis of the geometric parameters suggests that the pulling up of lower-buckled Si atoms by the AFM tip could be a key for high-resolution AFM, implying a weakening of the Si-Ag interactions at the interface. We expect that high-resolution AFM will also unveil atomic structures of edges and defects of silicene, or other emerging 2D materials.
Ruggeri, Marco; Major, James C.; McKeown, Craig; Knighton, Robert W.; Puliafito, Carmen A.
2010-01-01
Purpose. To reveal three-dimensional (3-D) information about the retinal structures of birds of prey in vivo. Methods. An ultra-high resolution spectral-domain optical coherence tomography (SD-OCT) system was built for in vivo imaging of retinas of birds of prey. The calibrated imaging depth and axial resolution of the system were 3.1 mm and 2.8 μm (in tissue), respectively. 3-D segmentation was performed for calculation of the retinal nerve fiber layer (RNFL) map. Results. High-resolution OCT images were obtained of the retinas of four species of birds of prey: two diurnal hawks (Buteo platypterus and Buteo brachyurus) and two nocturnal owls (Bubo virginianus and Strix varia). These images showed the detailed retinal anatomy, including the retinal layers and the structure of the deep and shallow foveae. The calculated thickness map showed the RNFL distribution. Traumatic injury to one bird's retina was also successfully imaged. Conclusions. Ultra-high resolution SD-OCT provides unprecedented high-quality 2-D and 3-D in vivo visualization of the retinal structures of birds of prey. SD-OCT is a powerful imaging tool for vision research in birds of prey. PMID:20554605
Shokri, Abbas; Eskandarloo, Amir; Norouzi, Marouf; Poorolajal, Jalal; Majidi, Gelareh; Aliyaly, Alireza
2018-03-01
This study compared the diagnostic accuracy of cone-beam computed tomography (CBCT) scans obtained with 2 CBCT systems with high- and low-resolution modes for the detection of root perforations in endodontically treated mandibular molars. The root canals of 72 mandibular molars were cleaned and shaped. Perforations measuring 0.2, 0.3, and 0.4 mm in diameter were created at the furcation area of 48 roots, simulating strip perforations, or on the external surfaces of 48 roots, simulating root perforations. Forty-eight roots remained intact (control group). The roots were filled using gutta-percha (Gapadent, Tianjin, China) and AH26 sealer (Dentsply Maillefer, Ballaigues, Switzerland). The CBCT scans were obtained using the NewTom 3G (QR srl, Verona, Italy) and Cranex 3D (Soredex, Helsinki, Finland) CBCT systems in high- and low-resolution modes, and were evaluated by 2 observers. The chi-square test was used to assess the nominal variables. In strip perforations, the accuracies of low- and high-resolution modes were 75% and 83% for NewTom 3G and 67% and 69% for Cranex 3D. In root perforations, the accuracies of low- and high-resolution modes were 79% and 83% for NewTom 3G and was 56% and 73% for Cranex 3D. The accuracy of the 2 CBCT systems was different for the detection of strip and root perforations. The Cranex 3D had non-significantly higher accuracy than the NewTom 3G. In both scanners, the high-resolution mode yielded significantly higher accuracy than the low-resolution mode. The diagnostic accuracy of CBCT scans was not affected by the perforation diameter.
High-resolution mapping of forest carbon stocks in the Colombian Amazon
NASA Astrophysics Data System (ADS)
Asner, G. P.; Clark, J. K.; Mascaro, J.; Galindo García, G. A.; Chadwick, K. D.; Navarrete Encinales, D. A.; Paez-Acosta, G.; Cabrera Montenegro, E.; Kennedy-Bowdoin, T.; Duque, Á.; Balaji, A.; von Hildebrand, P.; Maatoug, L.; Bernal, J. F. Phillips; Yepes Quintero, A. P.; Knapp, D. E.; García Dávila, M. C.; Jacobson, J.; Ordóñez, M. F.
2012-07-01
High-resolution mapping of tropical forest carbon stocks can assist forest management and improve implementation of large-scale carbon retention and enhancement programs. Previous high-resolution approaches have relied on field plot and/or light detection and ranging (LiDAR) samples of aboveground carbon density, which are typically upscaled to larger geographic areas using stratification maps. Such efforts often rely on detailed vegetation maps to stratify the region for sampling, but existing tropical forest maps are often too coarse and field plots too sparse for high-resolution carbon assessments. We developed a top-down approach for high-resolution carbon mapping in a 16.5 million ha region (> 40%) of the Colombian Amazon - a remote landscape seldom documented. We report on three advances for large-scale carbon mapping: (i) employing a universal approach to airborne LiDAR-calibration with limited field data; (ii) quantifying environmental controls over carbon densities; and (iii) developing stratification- and regression-based approaches for scaling up to regions outside of LiDAR coverage. We found that carbon stocks are predicted by a combination of satellite-derived elevation, fractional canopy cover and terrain ruggedness, allowing upscaling of the LiDAR samples to the full 16.5 million ha region. LiDAR-derived carbon maps have 14% uncertainty at 1 ha resolution, and the regional map based on stratification has 28% uncertainty in any given hectare. High-resolution approaches with quantifiable pixel-scale uncertainties will provide the most confidence for monitoring changes in tropical forest carbon stocks. Improved confidence will allow resource managers and decision makers to more rapidly and effectively implement actions that better conserve and utilize forests in tropical regions.
High-resolution Mapping of Forest Carbon Stocks in the Colombian Amazon
NASA Astrophysics Data System (ADS)
Asner, G. P.; Clark, J. K.; Mascaro, J.; Galindo García, G. A.; Chadwick, K. D.; Navarrete Encinales, D. A.; Paez-Acosta, G.; Cabrera Montenegro, E.; Kennedy-Bowdoin, T.; Duque, Á.; Balaji, A.; von Hildebrand, P.; Maatoug, L.; Bernal, J. F. Phillips; Knapp, D. E.; García Dávila, M. C.; Jacobson, J.; Ordóñez, M. F.
2012-03-01
High-resolution mapping of tropical forest carbon stocks can assist forest management and improve implementation of large-scale carbon retention and enhancement programs. Previous high-resolution approaches have relied on field plot and/or Light Detection and Ranging (LiDAR) samples of aboveground carbon density, which are typically upscaled to larger geographic areas using stratification maps. Such efforts often rely on detailed vegetation maps to stratify the region for sampling, but existing tropical forest maps are often too coarse and field plots too sparse for high resolution carbon assessments. We developed a top-down approach for high-resolution carbon mapping in a 16.5 million ha region (>40 %) of the Colombian Amazon - a remote landscape seldom documented. We report on three advances for large-scale carbon mapping: (i) employing a universal approach to airborne LiDAR-calibration with limited field data; (ii) quantifying environmental controls over carbon densities; and (iii) developing stratification- and regression-based approaches for scaling up to regions outside of LiDAR coverage. We found that carbon stocks are predicted by a combination of satellite-derived elevation, fractional canopy cover and terrain ruggedness, allowing upscaling of the LiDAR samples to the full 16.5 million ha region. LiDAR-derived carbon mapping samples had 14.6 % uncertainty at 1 ha resolution, and regional maps based on stratification and regression approaches had 25.6 % and 29.6 % uncertainty, respectively, in any given hectare. High-resolution approaches with reported local-scale uncertainties will provide the most confidence for monitoring changes in tropical forest carbon stocks. Improved confidence will allow resource managers and decision-makers to more rapidly and effectively implement actions that better conserve and utilize forests in tropical regions.
High resolution physical mapping of single gene fragments on pachytene chromosome 4 and 7 of Rosa.
Kirov, Ilya V; Van Laere, Katrijn; Khrustaleva, Ludmila I
2015-07-02
Rosaceae is a family containing many economically important fruit and ornamental species. Although fluorescence in situ hybridization (FISH)-based physical mapping of plant genomes is a valuable tool for map-based cloning, comparative genomics and evolutionary studies, no studies using high resolution physical mapping have been performed in this family. Previously we proved that physical mapping of single-copy genes as small as 1.1 kb is possible on mitotic metaphase chromosomes of Rosa wichurana using Tyramide-FISH. In this study we aimed to further improve the physical map of Rosa wichurana by applying high resolution FISH to pachytene chromosomes. Using high resolution Tyramide-FISH and multicolor Tyramide-FISH, 7 genes (1.7-3 kb) were successfully mapped on pachytene chromosomes 4 and 7 of Rosa wichurana. Additionally, by using multicolor Tyramide-FISH three closely located genes were simultaneously visualized on chromosome 7. A detailed map of heterochromatine/euchromatine patterns of chromosome 4 and 7 was developed with indication of the physical position of these 7 genes. Comparison of the gene order between Rosa wichurana and Fragaria vesca revealed a poor collinearity for chromosome 7, but a perfect collinearity for chromosome 4. High resolution physical mapping of short probes on pachytene chromosomes of Rosa wichurana was successfully performed for the first time. Application of Tyramide-FISH on pachytene chromosomes allowed the mapping resolution to be increased up to 20 times compared to mitotic metaphase chromosomes. High resolution Tyramide-FISH and multicolor Tyramide-FISH might become useful tools for further physical mapping of single-copy genes and for the integration of physical and genetic maps of Rosa wichurana and other members of the Rosaceae.
NASA Astrophysics Data System (ADS)
Van Gordon, M.; Van Gordon, S.; Min, A.; Sullivan, J.; Weiner, Z.; Tappan, G. G.
2017-12-01
Using support vector machine (SVM) learning and high-accuracy hand-classified maps, we have developed a publicly available land cover classification tool for the West African Sahel. Our classifier produces high-resolution and regionally calibrated land cover maps for the Sahel, representing a significant contribution to the data available for this region. Global land cover products are unreliable for the Sahel, and accurate land cover data for the region are sparse. To address this gap, the U.S. Geological Survey and the Regional Center for Agriculture, Hydrology and Meteorology (AGRHYMET) in Niger produced high-quality land cover maps for the region via hand-classification of Landsat images. This method produces highly accurate maps, but the time and labor required constrain the spatial and temporal resolution of the data products. By using these hand-classified maps alongside SVM techniques, we successfully increase the resolution of the land cover maps by 1-2 orders of magnitude, from 2km-decadal resolution to 30m-annual resolution. These high-resolution regionally calibrated land cover datasets, along with the classifier we developed to produce them, lay the foundation for major advances in studies of land surface processes in the region. These datasets will provide more accurate inputs for food security modeling, hydrologic modeling, analyses of land cover change and climate change adaptation efforts. The land cover classification tool we have developed will be publicly available for use in creating additional West Africa land cover datasets with future remote sensing data and can be adapted for use in other parts of the world.
NOAA's Use of High-Resolution Imagery
NASA Technical Reports Server (NTRS)
Hund, Erik
2007-01-01
NOAA's use of high-resolution imagery consists of: a) Shoreline mapping and nautical chart revision; b) Coastal land cover mapping; c) Benthic habitat mapping; d) Disaster response; and e) Imagery collection and support for coastal programs.
ALTERNATIVE DISINFECTANTS FOR DRINKING WATER
Using a combination of spectral identification techniques - gas chromatography coupled with low-and high-resolution electron-impact mass spectrometry (GC/EI-MS), low-and high-resolution chemical ionization mass spectrometry (GC/CI-MS), and Fourier transform infrared spectroscopy ...
High Resolution Global Topography of Eros from NEAR Imaging and LIDAR Data
NASA Technical Reports Server (NTRS)
Gaskell, Robert W.; Konopliv, A.; Barnouin-Jha, O.; Scheeres, D.
2006-01-01
Principal Data Products: Ensemble of L-maps from SPC, Spacecraft state, Asteroid pole and rotation. Secondary Products: Global topography model, inertia tensor, gravity. Composite high resolution topography. Three dimensional image maps.
Development of high resolution target monitor.
DOT National Transportation Integrated Search
2008-01-01
The proposed High-resolution Target Movement Monitor uses triangulation theory but in a unique way. Unlike the commercially available triangulation systems which use sensing diodes to perceive reflected laser signatures and are limited to very short ...
Atmospheric Science Data Center
2016-06-24
... data granules using a high resolution spatial metadata database and directly accessing the archived data granules. Subset results are ... data granules using a high resolution spatial metadata database and directly accessing the archived data granules. Subset results are ...
Publications - GMC 414 | Alaska Division of Geological & Geophysical
DGGS GMC 414 Publication Details Title: Sensitive High Resolution Ion Micro Probe (SHRIMP) data of Gottlieb, E., 2012, Sensitive High Resolution Ion Micro Probe (SHRIMP) data of outcrop samples from the
Conceptual study of an optical aperture synthesis system for high resolution astronomy
NASA Astrophysics Data System (ADS)
Calvel, Bertrand
2018-04-01
This paper, "Conceptual study of an optical aperture synthesis system for high resolution astronomy," was presented as part of International Conference on Space Optics—ICSO 1997, held in Toulouse, France.
Next Generation X-Ray Observatory: New Mission Concepts in Astrophysics
NASA Technical Reports Server (NTRS)
Cash, Webster
1998-01-01
This grant was to review the impact and possibilities for high resolution imaging as the theme for a new observatory early in the 21st Century. We proposed to investigate the suitability of a new approach to high resolution x-ray optics and investigate the range of science it might support. There is no question that high resolution x-ray imaging would lead to exciting, fundamental new discoveries. We demonstrated in this study that the technology already exists to improve imaging in the x-ray by up to six orders of magnitude. This would make the x-ray band the highest resolution band instead of its current status as second worst, behind gamma rays.
Label-free imaging of cellular malformation using high resolution photoacoustic microscopy
NASA Astrophysics Data System (ADS)
Chen, Zhongjiang; Li, Bingbing; Yang, Sihua
2014-09-01
A label-free high resolution photoacoustic microscopy (PAM) system for imaging cellular malformation is presented. The carbon fibers were used to testify the lateral resolution of the PAM. Currently, the lateral resolution is better than 2.7 μm. The human normal red blood cells (RBCs) were used to prove the imaging capability of the system, and a single red blood cell was mapped with high contrast. Moreover, the iron deficiency anemia RBCs were clearly distinguished from the cell morphology by using the PAM. The experimental results demonstrate that the photoacoustic microscopy system can accomplish label-free photoacoustic imaging and that it has clinical potential for use in the detection of erythrocytes and blood vessels malformation.
High resolution spectroscopy in the microwave and far infrared
NASA Technical Reports Server (NTRS)
Pickett, Herbert M.
1990-01-01
High resolution rotational spectroscopy has long been central to remote sensing techniques in atmospheric sciences and astronomy. As such, laboratory measurements must supply the required data to make direct interpretation of data for instruments which sense atmospheres using rotational spectra. Spectral measurements in the microwave and far infrared regions are also very powerful tools when combined with infrared measurements for characterizing the rotational structure of vibrational spectra. In the past decade new techniques were developed which have pushed high resolution spectroscopy into the wavelength region between 25 micrometers and 2 mm. Techniques to be described include: (1) harmonic generation of microwave sources, (2) infrared laser difference frequency generation, (3) laser sideband generation, and (4) ultrahigh resolution interferometers.
Re-scan confocal microscopy: scanning twice for better resolution
De Luca, Giulia M.R.; Breedijk, Ronald M.P.; Brandt, Rick A.J.; Zeelenberg, Christiaan H.C.; de Jong, Babette E.; Timmermans, Wendy; Azar, Leila Nahidi; Hoebe, Ron A.; Stallinga, Sjoerd; Manders, Erik M.M.
2013-01-01
We present a new super-resolution technique, Re-scan Confocal Microscopy (RCM), based on standard confocal microscopy extended with an optical (re-scanning) unit that projects the image directly on a CCD-camera. This new microscope has improved lateral resolution and strongly improved sensitivity while maintaining the sectioning capability of a standard confocal microscope. This simple technology is typically useful for biological applications where the combination high-resolution and high-sensitivity is required. PMID:24298422
High resolution frequency analysis techniques with application to the redshift experiment
NASA Technical Reports Server (NTRS)
Decher, R.; Teuber, D.
1975-01-01
High resolution frequency analysis methods, with application to the gravitational probe redshift experiment, are discussed. For this experiment a resolution of .00001 Hz is required to measure a slowly varying, low frequency signal of approximately 1 Hz. Major building blocks include fast Fourier transform, discrete Fourier transform, Lagrange interpolation, golden section search, and adaptive matched filter technique. Accuracy, resolution, and computer effort of these methods are investigated, including test runs on an IBM 360/65 computer.
Multibeam interferometric illumination as the primary source of resolution in optical microscopy
NASA Astrophysics Data System (ADS)
Ryu, J.; Hong, S. S.; Horn, B. K. P.; Freeman, D. M.; Mermelstein, M. S.
2006-04-01
High-resolution images of a fluorescent target were obtained using a low-resolution optical detector by illuminating the target with interference patterns produced with 31 coherent beams. The beams were arranged in a cone with 78° half angle to produce illumination patterns consistent with a numerical aperture of 0.98. High-resolution images were constructed from low-resolution images taken with 930 different illumination patterns. Results for optical detectors with numerical apertures of 0.1 and 0.2 were similar, demonstrating that the resolution is primarily determined by the illuminator and not by the low-resolution detector. Furthermore, the long working distance, large depth of field, and large field of view of the low-resolution detector are preserved.
Analyzing and leveraging self-similarity for variable resolution atmospheric models
NASA Astrophysics Data System (ADS)
O'Brien, Travis; Collins, William
2015-04-01
Variable resolution modeling techniques are rapidly becoming a popular strategy for achieving high resolution in a global atmospheric models without the computational cost of global high resolution. However, recent studies have demonstrated a variety of resolution-dependent, and seemingly artificial, features. We argue that the scaling properties of the atmosphere are key to understanding how the statistics of an atmospheric model should change with resolution. We provide two such examples. In the first example we show that the scaling properties of the cloud number distribution define how the ratio of resolved to unresolved clouds should increase with resolution. We show that the loss of resolved clouds, in the high resolution region of variable resolution simulations, with the Community Atmosphere Model version 4 (CAM4) is an artifact of the model's treatment of condensed water (this artifact is significantly reduced in CAM5). In the second example we show that the scaling properties of the horizontal velocity field, combined with the incompressibility assumption, necessarily result in an intensification of vertical mass flux as resolution increases. We show that such an increase is present in a wide variety of models, including CAM and the regional climate models of the ENSEMBLES intercomparision. We present theoretical arguments linking this increase to the intensification of precipitation with increasing resolution.
Improved Resolution Optical Time Stretch Imaging Based on High Efficiency In-Fiber Diffraction.
Wang, Guoqing; Yan, Zhijun; Yang, Lei; Zhang, Lin; Wang, Chao
2018-01-12
Most overlooked challenges in ultrafast optical time stretch imaging (OTSI) are sacrificed spatial resolution and higher optical loss. These challenges are originated from optical diffraction devices used in OTSI, which encode image into spectra of ultrashort optical pulses. Conventional free-space diffraction gratings, as widely used in existing OTSI systems, suffer from several inherent drawbacks: limited diffraction efficiency in a non-Littrow configuration due to inherent zeroth-order reflection, high coupling loss between free-space gratings and optical fibers, bulky footprint, and more importantly, sacrificed imaging resolution due to non-full-aperture illumination for individual wavelengths. Here we report resolution-improved and diffraction-efficient OTSI using in-fiber diffraction for the first time to our knowledge. The key to overcome the existing challenges is a 45° tilted fiber grating (TFG), which serves as a compact in-fiber diffraction device offering improved diffraction efficiency (up to 97%), inherent compatibility with optical fibers, and improved imaging resolution owning to almost full-aperture illumination for all illumination wavelengths. 50 million frames per second imaging of fast moving object at 46 m/s with improved imaging resolution has been demonstrated. This conceptually new in-fiber diffraction design opens the way towards cost-effective, compact and high-resolution OTSI systems for image-based high-throughput detection and measurement.
Garcia-Sucerquia, J; Alvarez-Palacio, D C; Kreuzer, H J
2008-09-10
We report the observation of the Talbot self-imaging effect in high resolution digital in-line holographic microscopy (DIHM) and its application to structural characterization of periodic samples. Holograms of self-assembled monolayers of micron-sized polystyrene spheres are reconstructed at different image planes. The point-source method of DIHM and the consequent high lateral resolution allows the true image (object) plane to be identified. The Talbot effect is then exploited to improve the evaluation of the pitch of the assembly and to examine defects in its periodicity.
The high-resolution Doppler imager on the Upper Atmosphere Research Satellite
NASA Technical Reports Server (NTRS)
Hays, Paul B.; Abreu, Vincent J.; Dobbs, Michael E.; Gell, David A.; Grassl, Heinz J.; Skinner, Wilbert R.
1993-01-01
The high-resolution Doppler imager (HRDI) on the Upper Atmosphere Research Satellite is a triple-etalon Fabry-Perot interferometer designed to measure winds in the stratosphere, mesosphere, and lower thermosphere. Winds are determined by measuring the Doppler shifts of rotational lines of the O2 atmospheric band, which are observed in emission in the mesosphere and lower thermosphere and in absorption in the stratosphere. The interferometer has high resolution (0.05/cm), good offhand rejection, aud excellent stability. This paper provides details of the design and capabilities of the HRDI instrument.
1999-09-28
part of the talk will be devoted to the high resolution ab- sorption spectroscopy of the vi = 2-6 acetylenic overtone bands of propyned (CH 3-C=C-H...period CATGAS (Calibration Apparatus for Trace GAs Spectra), a transportable laboratory set-up for ab- sorption spectroscopy, was connected to the...the NIR around 1.95- 2.04 nm and 2.26- 2.39 nm, where accurate line parameters of ozone ab- sorption are available by high-resolution Fourier transform
1992-05-29
Spectroscopy of 1,2- Difluoroethane in a Molecular Beam: A Case Study of Vibrational Mode-Coupling by Steven W. Mork, C. Cameron Miller, and Laura A...and sale; its distribution is unlimited. 92-14657 l9lll l l l , II a HIGH RESOLUTION SPECTROSCOPY OF 1,2- DIFLUOROETHANE IN A MOLECULAR BEAM: A CASE...14853-1301 Abstract The high resolution infrared spectrum of 1,2- difluoroethane (DFE) in a molecular beam has been obtained over the 2978-2996 cm-1
Moon Mineralogy Mapper: Unlocking the Mysteries of the Moon
NASA Technical Reports Server (NTRS)
Runyon, Cassandra
2006-01-01
Moon Mineralogy Mapper (M3) is a state-of-the-art high spectral resolution imaging spectrometer that will characterize and map the mineral composition of the Moon. The M3 instrument will be flown on Chandrayaan-I, the Indian Space Research Organization (ISRO) mission to be launched in March 2008. The Moon is a cornerstone to understanding early solar system processes. M3 high-resolution compositional maps will dramatically improve our understanding about the early evolution of the terrestrial planets and will provide an assessment of lunar resources at high spatial resolution.
An interferometer for high-resolution optical surveillance from geostationary orbit
NASA Astrophysics Data System (ADS)
Bonino, L.; Bresciani, F.; Piasini, G.; Flebus, C.; Lecat, J.-H.; Roose, S.; Pisani, M.; Cabral, A.; Rebordão, J.; Proença, C.; Costal, J.; Lima, P. U.; Loix, N.; Musso, F.
2017-11-01
The activities described in this paper have been developed in the frame of the EUCLID CEPA 9 RTP 9.9 "High Resolution Optical Satellite Sensor" project of the WEAO Research Cell. They have been focused on the definition of an interferometric instrument optimised for the high-resolution optical surveillance from geostationary orbit (GEO) by means of the synthetic aperture technique, and on the definition and development of the related enabling technologies. In this paper we describe the industrial team, the selected mission specifications and overview of the whole design and manufacturing activities performed.
High resolution observations: The state of the art and beyond
NASA Technical Reports Server (NTRS)
Title, A.; Tarbell, T.; Shine, R.; Topka, K.; Frank, Z.
1992-01-01
The meaning of high resolution and its scientific importance with regard to solar observations is discussed. The state of the art is reviewed, looking into Solar Optical Universal Polarimeter (SOUP) observations, image selection techniques, and adaptive optics. It is concluded that until there are observations in space, complete understanding of processes in the solar photosphere, chromosphere, transition region, and corona will be impossible. The importance of high resolution is considered with regard to solar surface and convection, solar photosphere inside and outside magnetic fields, and sunspot geometry.
Diagnostic and functional structure of a high-resolution thyroid nodule clinic.
Fernández-García, José Carlos; Mancha-Doblas, Isabel; Ortega-Jiménez, María Victoria; Ruiz-Escalante, José Francisco; Castells-Fusté, Ignasi; Tofé-Povedano, Santiago; Argüelles-Jiménez, Iñaki; Tinahones, Francisco José
2014-01-01
Appearance of a thyroid nodule has become a daily occurrence in clinical practice. Adequate thyroid nodule assessment requires several diagnostic tests and multiple medical appointments, which results in a substantial delay in diagnosis. Implementation of a high-resolution thyroid nodule clinic largely avoids these drawbacks by condensing in a single appointment all tests required for adequate evaluation of thyroid nodule. This paper reviews the diagnostic and functional structure of a high-resolution thyroid nodule clinic. Copyright © 2013 SEEN. Published by Elsevier Espana. All rights reserved.
A High Resolution Scale-of-four
DOE R&D Accomplishments Database
Fitch, V.
1949-08-25
A high resolution scale-of-four has been developed to be used in conjunction with the nuclear particle detection devices in applications where the counting rate is unusually high. Specifically, it is intended to precede the commercially available medium resolution scaling circuits and so decrease the resolving time of the counting system. The circuit will function reliably on continuously recurring pulses separated by less than 0.1 microseconds. It will resolve two pulses (occurring at a moderate repetition rate) which are spaced at 0.04 microseconds. A five-volt input signal is sufficient to actuate the device.
Sub-25-nm laboratory x-ray microscopy using a compound Fresnel zone plate.
von Hofsten, Olov; Bertilson, Michael; Reinspach, Julia; Holmberg, Anders; Hertz, Hans M; Vogt, Ulrich
2009-09-01
Improving the resolution in x-ray microscopes is of high priority to enable future applications in nanoscience. However, high-resolution zone-plate optics often have low efficiency, which makes implementation in laboratory microscopes difficult. We present a laboratory x-ray microscope based on a compound zone plate. The compound zone plate utilizes multiple diffraction orders to achieve high resolution while maintaining reasonable efficiency. We analyze the illumination conditions necessary for this type of optics in order to suppress stray light and demonstrate microscopic imaging resolving 25 nm features.
Characterization of fiber Bragg grating-based sensor array for high resolution manometry
NASA Astrophysics Data System (ADS)
Becker, Martin; Rothhardt, Manfred; Schröder, Kerstin; Voigt, Sebastian; Mehner, Jan; Teubner, Andreas; Lüpke, Thomas; Thieroff, Christoph; Krüger, Matthias; Chojetzki, Christoph; Bartelt, Hartmut
2012-04-01
The combination of fiber Bragg grating arrays integrated in a soft plastic tube is promising for high resolution manometry (HRM) where pressure measurements are done with high spatial resolution. The application as a medical device and in vivo experiments have to be anticipated by characterization with a measurement setup that simulates natural conditions. Good results are achieved with a pressure chamber which applies a well-defined pressure with a soft tubular membrane. It is shown that the proposed catheter design reaches accuracies down to 1 mbar and 1 cm.
NASA Astrophysics Data System (ADS)
Crawford, S. M.; Crause, Lisa; Depagne, Éric; Ilkiewicz, Krystian; Schroeder, Anja; Kuhn, Rudolph; Hettlage, Christian; Romero Colmenaro, Encarni; Kniazev, Alexei; Väisänen, Petri
2016-08-01
The High Resolution Spectrograph (HRS) on the Southern African Large Telescope (SALT) is a dual beam, fiber-fed echelle spectrograph providing high resolution capabilities to the SALT observing community. We describe the available data reduction tools and the procedures put in place for regular monitoring of the data quality from the spectrograph. Data reductions are carried out through the pyhrs package. The data characteristics and instrument stability are reported as part of the SALT Dashboard to help monitor the performance of the instrument.
NASA Astrophysics Data System (ADS)
Erskine, David J.; Edelstein, J.; Sirk, M.; Wishnow, E.; Ishikawa, Y.; McDonald, E.; Shourt, W. V.
2014-07-01
High resolution broad-band spectroscopy at near-infrared wavelengths has been performed using externally dis- persed interferometry (EDI) at the Hale telescope at Mt. Palomar. The EDI technique uses a field-widened Michelson interferometer in series with a dispersive spectrograph, and is able to recover a spectrum with a resolution 4 to 10 times higher than the existing grating spectrograph. This method increases the resolution well beyond the classical limits enforced by the slit width and the detector pixel Nyquist limit and, in principle, decreases the effect of pupil variation on the instrument line-shape function. The EDI technique permits arbi- trarily higher resolution measurements using the higher throughput, lower weight, size, and expense of a lower resolution spectrograph. Observations of many stars were performed with the TEDI interferometer mounted within the central hole of the 200 inch primary mirror. Light from the interferometer was then dispersed by the TripleSpec near-infrared echelle spectrograph. Continuous spectra between 950 and 2450 nm with a resolution as high as ~27,000 were recovered from data taken with TripleSpec at a native resolution of ˜2,700. Aspects of data analysis for interferometric spectral reconstruction are described. This technique has applications in im- proving measurements of high-resolution stellar template spectra, critical for precision Doppler velocimetry using conventional spectroscopic methods. A new interferometer to be applied for this purpose at visible wavelengths is under construction.
Improving axial resolution in confocal microscopy with new high refractive index mounting media.
Fouquet, Coralie; Gilles, Jean-François; Heck, Nicolas; Dos Santos, Marc; Schwartzmann, Richard; Cannaya, Vidjeacoumary; Morel, Marie-Pierre; Davidson, Robert Stephen; Trembleau, Alain; Bolte, Susanne
2015-01-01
Resolution, high signal intensity and elevated signal to noise ratio (SNR) are key issues for biologists who aim at studying the localisation of biological structures at the cellular and subcellular levels using confocal microscopy. The resolution required to separate sub-cellular biological structures is often near to the resolving power of the microscope. When optimally used, confocal microscopes may reach resolutions of 180 nm laterally and 500 nm axially, however, axial resolution in depth is often impaired by spherical aberration that may occur due to refractive index mismatches. Spherical aberration results in broadening of the point-spread function (PSF), a decrease in peak signal intensity when imaging in depth and a focal shift that leads to the distortion of the image along the z-axis and thus in a scaling error. In this study, we use the novel mounting medium CFM3 (Citifluor Ltd., UK) with a refractive index of 1.518 to minimize the effects of spherical aberration. This mounting medium is compatible with most common fluorochromes and fluorescent proteins. We compare its performance with established mounting media, harbouring refractive indices below 1.500, by estimating lateral and axial resolution with sub-resolution fluorescent beads. We show furthermore that the use of the high refractive index media renders the tissue transparent and improves considerably the axial resolution and imaging depth in immuno-labelled or fluorescent protein labelled fixed mouse brain tissue. We thus propose to use those novel high refractive index mounting media, whenever optimal axial resolution is required.
NASA Astrophysics Data System (ADS)
Yamamoto, Seiichi; Kawaguchi, Wataru
2018-06-01
For precise distribution measurements of alpha particles, a high-resolution alpha particle imaging detector is required. Although combining a thin scintillator with a silicon photomultiplier (Si-PM) array is a promising method for achieving high resolution, the spatial resolution is limited. Reducing the size of the Si-PM array is a possible approach to improving the spatial resolution of the alpha particle imaging detector. Consequently, we employed a 1 mm channel size Si-PM array combined with a thin ZnS(Ag) sheet to form an alpha particle imaging detector and evaluated the performance. For the developed alpha particle imaging detector, an Si-PM array with 1 mm x 1 mm channel size arranged 8 x 8 was optically coupled to a ZnS(Ag) sheet with a 1-mm-thick light guide between them. The size of the alpha particle imaging detector was 9.5 mm x 9.5 mm. The spatial resolution of the developed alpha particle imaging detector was 0.14 mm FWHM, and the energy resolution was 74% FWHM for 5.5 MeV alpha particles. The uniformity of the imaging detector at the central part of the field of view (FOV) was ±4.7%. The background count rate was 0.06 counts/min. We obtained various high-resolution phantom images for alpha particles with the developed system. We conclude that the developed imaging detector is promising for high-resolution distribution measurements of alpha particles.
High-resolution clustered pinhole (131)Iodine SPECT imaging in mice.
van der Have, Frans; Ivashchenko, Oleksandra; Goorden, Marlies C; Ramakers, Ruud M; Beekman, Freek J
2016-08-01
High-resolution pre-clinical (131)I SPECT can facilitate development of new radioiodine therapies for cancer. To this end, it is important to limit resolution-degrading effects of pinhole edge penetration by the high-energy γ-photons of iodine. Here we introduce, optimize and validate (131)I SPECT performed with a dedicated high-energy clustered multi-pinhole collimator. A SPECT-CT system (VECTor/CT) with stationary gamma-detectors was equipped with a tungsten collimator with clustered pinholes. Images were reconstructed with pixel-based OSEM, using a dedicated (131)I system matrix that models the distance- and energy-dependent resolution and sensitivity of each pinhole, as well as the intrinsic detector blurring and variable depth of interaction in the detector. The system performance was characterized with phantoms and in vivo static and dynamic (131)I-NaI scans of mice. Reconstructed image resolution reached 0.6mm, while quantitative accuracy measured with a (131)I filled syringe reaches an accuracy of +3.6±3.5% of the gold standard value. In vivo mice scans illustrated a clear shape of the thyroid and biodistribution of (131)I within the animal. Pharmacokinetics of (131)I was assessed with 15-s time frames from the sequence of dynamic images and time-activity curves of (131)I-NaI. High-resolution quantitative and fast dynamic (131)I SPECT in mice is possible by means of a high-energy collimator and optimized system modeling. This enables analysis of (131)I uptake even within small organs in mice, which can be highly valuable for development and optimization of targeted cancer therapies. Copyright © 2016 Elsevier Inc. All rights reserved.
Liebisch, Frank; Walter, Achim; Greven, Hartmut; Rascher, Uwe
2013-01-01
Background Most spectral data for the amphibian integument are limited to the visible spectrum of light and have been collected using point measurements with low spatial resolution. In the present study a dual camera setup consisting of two push broom hyperspectral imaging systems was employed, which produces reflectance images between 400 and 2500 nm with high spectral and spatial resolution and a high dynamic range. Methodology/Principal Findings We briefly introduce the system and document the high efficiency of this technique analyzing exemplarily the spectral reflectivity of the integument of three arboreal anuran species (Litoria caerulea, Agalychnis callidryas and Hyla arborea), all of which appear green to the human eye. The imaging setup generates a high number of spectral bands within seconds and allows non-invasive characterization of spectral characteristics with relatively high working distance. Despite the comparatively uniform coloration, spectral reflectivity between 700 and 1100 nm differed markedly among the species. In contrast to H. arborea, L. caerulea and A. callidryas showed reflection in this range. For all three species, reflectivity above 1100 nm is primarily defined by water absorption. Furthermore, the high resolution allowed examining even small structures such as fingers and toes, which in A. callidryas showed an increased reflectivity in the near infrared part of the spectrum. Conclusion/Significance Hyperspectral imaging was found to be a very useful alternative technique combining the spectral resolution of spectrometric measurements with a higher spatial resolution. In addition, we used Digital Infrared/Red-Edge Photography as new simple method to roughly determine the near infrared reflectivity of frog specimens in field, where hyperspectral imaging is typically difficult. PMID:24058464
Anderson, David M. G.; Mills, Daniel; Spraggins, Jeffrey; Lambert, Wendi S.; Calkins, David J.
2013-01-01
Purpose To develop a method for generating high spatial resolution (10 µm) matrix-assisted laser desorption ionization (MALDI) images of lipids in rodent optic nerve tissue. Methods Ice-embedded optic nerve tissue from rats and mice were cryosectioned across the coronal and sagittal axes of the nerve fiber. Sections were thaw mounted on gold-coated MALDI plates and were washed with ammonium acetate to remove biologic salts before being coated in 2,5-dihydroxybenzoic acid by sublimation. MALDI images were generated in positive and negative ion modes at 10 µm spatial resolution. Lipid identification was performed with a high mass resolution Fourier transform ion cyclotron resonance mass spectrometer. Results Several lipid species were observed with high signal intensity in MALDI images of optic nerve tissue. Several lipids were localized to specific structures including in the meninges surrounding the optic nerve and in the central neuronal tissue. Specifically, phosphatidylcholine species were observed throughout the nerve tissue in positive ion mode while sulfatide species were observed in high abundance in the meninges surrounding the optic nerve in negative ion mode. Accurate mass measurements and fragmentation using sustained off-resonance irradiation with a high mass resolution Fourier transform ion cyclotron resonance mass spectrometer instrument allowed for identification of lipid species present in the small structure of the optic nerve directly from tissue sections. Conclusions An optimized sample preparation method provides excellent sensitivity for lipid species present within optic nerve tissue. This allowed the laser spot size and fluence to be reduced to obtain a high spatial resolution of 10 µm. This new imaging modality can now be applied to determine spatial and molecular changes in optic nerve tissue with disease. PMID:23559852
NASA Technical Reports Server (NTRS)
Mankbadi, M. R.; Georgiadis, N. J.; DeBonis, J. R.
2015-01-01
The objective of this work is to compare a high-order solver with a low-order solver for performing large-eddy simulations (LES) of a compressible mixing layer. The high-order method is the Wave-Resolving LES (WRLES) solver employing a Dispersion Relation Preserving (DRP) scheme. The low-order solver is the Wind-US code, which employs the second-order Roe Physical scheme. Both solvers are used to perform LES of the turbulent mixing between two supersonic streams at a convective Mach number of 0.46. The high-order and low-order methods are evaluated at two different levels of grid resolution. For a fine grid resolution, the low-order method produces a very similar solution to the high-order method. At this fine resolution the effects of numerical scheme, subgrid scale modeling, and filtering were found to be negligible. Both methods predict turbulent stresses that are in reasonable agreement with experimental data. However, when the grid resolution is coarsened, the difference between the two solvers becomes apparent. The low-order method deviates from experimental results when the resolution is no longer adequate. The high-order DRP solution shows minimal grid dependence. The effects of subgrid scale modeling and spatial filtering were found to be negligible at both resolutions. For the high-order solver on the fine mesh, a parametric study of the spanwise width was conducted to determine its effect on solution accuracy. An insufficient spanwise width was found to impose an artificial spanwise mode and limit the resolved spanwise modes. We estimate that the spanwise depth needs to be 2.5 times larger than the largest coherent structures to capture the largest spanwise mode and accurately predict turbulent mixing.
High resolution imaging of a subsonic projectile using automated mirrors with large aperture
NASA Astrophysics Data System (ADS)
Tateno, Y.; Ishii, M.; Oku, H.
2017-02-01
Visual tracking of high-speed projectiles is required for studying the aerodynamics around the objects. One solution to this problem is a tracking method based on the so-called 1 ms Auto Pan-Tilt (1ms-APT) system that we proposed in previous work, which consists of rotational mirrors and a high-speed image processing system. However, the images obtained with that system did not have high enough resolution to realize detailed measurement of the projectiles because of the size of the mirrors. In this study, we propose a new system consisting of enlarged mirrors for tracking a high-speed projectiles so as to achieve higher-resolution imaging, and we confirmed the effectiveness of the system via an experiment in which a projectile flying at subsonic speed tracked.
NASA Astrophysics Data System (ADS)
Yamanaka, Masahito; Kawagoe, Hiroyuki; Nishizawa, Norihiko
2016-02-01
We describe the generation of a high-power, spectrally smooth supercontinuum (SC) in the 1600 nm spectral band for ultrahigh-resolution optical coherence tomography (UHR-OCT). A clean SC was achieved by using a highly nonlinear fiber with normal dispersion properties and a high-quality pedestal-free pulse obtained from a passively mode-locked erbium-doped fiber laser operating at 182 MHz. The center wavelength and spectral width were 1578 and 172 nm, respectively. The output power of the SC was 51 mW. Using the developed SC source, we demonstrated UHR-OCT imaging of biological samples with a sensitivity of 109 dB and an axial resolution of 4.9 µm in tissue.
Ultra-long high-sensitivity Φ-OTDR for high spatial resolution intrusion detection of pipelines.
Peng, Fei; Wu, Han; Jia, Xin-Hong; Rao, Yun-Jiang; Wang, Zi-Nan; Peng, Zheng-Pu
2014-06-02
An ultra-long phase-sensitive optical time domain reflectometry (Φ-OTDR) that can achieve high-sensitivity intrusion detection over 131.5km fiber with high spatial resolution of 8m is presented, which is the longest Φ-OTDR reported to date, to the best of our knowledge. It is found that the combination of distributed Raman amplification with heterodyne detection can extend the sensing distance and enhances the sensitivity substantially, leading to the realization of ultra-long Φ-OTDR with high sensitivity and spatial resolution. Furthermore, the feasibility of applying such an ultra-long Φ-OTDR to pipeline security monitoring is demonstrated and the features of intrusion signal can be extracted with improved SNR by using the wavelet detrending/denoising method proposed.
Wide-aperture aspherical lens for high-resolution terahertz imaging
NASA Astrophysics Data System (ADS)
Chernomyrdin, Nikita V.; Frolov, Maxim E.; Lebedev, Sergey P.; Reshetov, Igor V.; Spektor, Igor E.; Tolstoguzov, Viktor L.; Karasik, Valeriy E.; Khorokhorov, Alexei M.; Koshelev, Kirill I.; Schadko, Aleksander O.; Yurchenko, Stanislav O.; Zaytsev, Kirill I.
2017-01-01
In this paper, we introduce wide-aperture aspherical lens for high-resolution terahertz (THz) imaging. The lens has been designed and analyzed by numerical methods of geometrical optics and electrodynamics. It has been made of high-density polyethylene by shaping at computer-controlled lathe and characterized using a continuous-wave THz imaging setup based on a backward-wave oscillator and Golay detector. The concept of image contrast has been implemented to estimate image quality. According to the experimental data, the lens allows resolving two points spaced at 0.95λ distance with a contrast of 15%. To highlight high resolution in the THz images, the wide-aperture lens has been employed for studying printed electronic circuit board containing sub-wavelength-scale elements. The observed results justify the high efficiency of the proposed lens design.
Souma, S; Sato, T; Takahashi, T; Baltzer, P
2007-12-01
We have developed a highly brilliant xenon (Xe) discharge lamp operated by microwave-induced electron cyclotron resonance (ECR) for ultrahigh-resolution bulk-sensitive photoemission spectroscopy (PES). We observed at least eight strong radiation lines from neutral or singly ionized Xe atoms in the energy region of 8.4-10.7 eV. The photon flux of the strongest Xe I resonance line at 8.437 eV is comparable to that of the He Ialpha line (21.218 eV) from the He-ECR discharge lamp. Stable operation for more than 300 h is achieved by efficient air-cooling of a ceramic tube in the resonance cavity. The high bulk sensitivity and high-energy resolution of PES using the Xe lines are demonstrated for some typical materials.
Lubin, Hodney; Dupuis, Christophe; Pytkowicz, Julien; Brigaud, Thierry
2013-04-05
A highly efficient crystallization-induced dynamic resolution (CIDR) of trans-Fox (fluorinated oxazolidine) chiral auxiliary is reported. This chiral auxiliary was used for highly diastereoselective (>98% de) electrophilic fluorination of amide enolates. After removal of the chiral auxiliary, highly valuable enantiopure α-fluorocarboxylic acids and β-fluoroalcohols are obtained.
ERIC First Analysis: Agricultural Policy. 1986-87 National High School Debate Resolutions.
ERIC Educational Resources Information Center
Wagner, David L.; Fraleigh, Douglas
Designed to serve as a framework in which high school debate students, coaches, and judges can evaluate the issues, arguments, and evidence concerning which agricultural policies best serve the United States, this booklet provides guidelines for research on the 1986-87 debate resolutions selected by the National Federation of State High School…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Margaryan, Amur
2011-10-01
A new timing technique for single photons based on the radio frequency phototube and optical clock or femtosecond optical frequency comb generator is proposed. The technique has a 20 ps resolution for single photons, is capable of operating with MHz frequencies and achieving 10 fs instability level.
High resolution metric imaging payload
NASA Astrophysics Data System (ADS)
Delclaud, Y.
2017-11-01
Alcatel Space Industries has become Europe's leader in the field of high and very high resolution optical payloads, in the frame work of earth observation system able to provide military government with metric images from space. This leadership allowed ALCATEL to propose for the export market, within a French collaboration frame, a complete space based system for metric observation.
Enhancing GIS Capabilities for High Resolution Earth Science Grids
NASA Astrophysics Data System (ADS)
Koziol, B. W.; Oehmke, R.; Li, P.; O'Kuinghttons, R.; Theurich, G.; DeLuca, C.
2017-12-01
Applications for high performance GIS will continue to increase as Earth system models pursue more realistic representations of Earth system processes. Finer spatial resolution model input and output, unstructured or irregular modeling grids, data assimilation, and regional coordinate systems present novel challenges for GIS frameworks operating in the Earth system modeling domain. This presentation provides an overview of two GIS-driven applications that combine high performance software with big geospatial datasets to produce value-added tools for the modeling and geoscientific community. First, a large-scale interpolation experiment using National Hydrography Dataset (NHD) catchments, a high resolution rectilinear CONUS grid, and the Earth System Modeling Framework's (ESMF) conservative interpolation capability will be described. ESMF is a parallel, high-performance software toolkit that provides capabilities (e.g. interpolation) for building and coupling Earth science applications. ESMF is developed primarily by the NOAA Environmental Software Infrastructure and Interoperability (NESII) group. The purpose of this experiment was to test and demonstrate the utility of high performance scientific software in traditional GIS domains. Special attention will be paid to the nuanced requirements for dealing with high resolution, unstructured grids in scientific data formats. Second, a chunked interpolation application using ESMF and OpenClimateGIS (OCGIS) will demonstrate how spatial subsetting can virtually remove computing resource ceilings for very high spatial resolution interpolation operations. OCGIS is a NESII-developed Python software package designed for the geospatial manipulation of high-dimensional scientific datasets. An overview of the data processing workflow, why a chunked approach is required, and how the application could be adapted to meet operational requirements will be discussed here. In addition, we'll provide a general overview of OCGIS's parallel subsetting capabilities including challenges in the design and implementation of a scientific data subsetter.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ogura, Toshihiko, E-mail: t-ogura@aist.go.jp
Highlights: • We developed a high-sensitive frequency transmission electric-field (FTE) system. • The output signal was highly enhanced by applying voltage to a metal layer on SiN. • The spatial resolution of new FTE method is 41 nm. • New FTE system enables observation of the intact bacteria and virus in water. - Abstract: The high-resolution structural analysis of biological specimens by scanning electron microscopy (SEM) presents several advantages. Until now, wet bacterial specimens have been examined using atmospheric sample holders. However, images of unstained specimens in water using these holders exhibit very poor contrast and heavy radiation damage. Recently,more » we developed the frequency transmission electric-field (FTE) method, which facilitates the SEM observation of biological specimens in water without radiation damage. However, the signal detection system presents low sensitivity. Therefore, a high EB current is required to generate clear images, and thus reducing spatial resolution and inducing thermal damage to the samples. Here a high-sensitivity detection system is developed for the FTE method, which enhances the output signal amplitude by hundredfold. The detection signal was highly enhanced when voltage was applied to the metal layer on silicon nitride thin film. This enhancement reduced the EB current and improved the spatial resolution as well as the signal-to-noise ratio. The spatial resolution of a high-sensitive FTE system is 41 nm, which is considerably higher than previous FTE system. New FTE system can easily be utilised to examine various unstained biological specimens in water, such as living bacteria and viruses.« less
Development of an immersive virtual reality head-mounted display with high performance.
Wang, Yunqi; Liu, Weiqi; Meng, Xiangxiang; Fu, Hanyi; Zhang, Daliang; Kang, Yusi; Feng, Rui; Wei, Zhonglun; Zhu, Xiuqing; Jiang, Guohua
2016-09-01
To resolve the contradiction between large field of view and high resolution in immersive virtual reality (VR) head-mounted displays (HMDs), an HMD monocular optical system with a large field of view and high resolution was designed. The system was fabricated by adopting aspheric technology with CNC grinding and a high-resolution LCD as the image source. With this monocular optical system, an HMD binocular optical system with a wide-range continuously adjustable interpupillary distance was achieved in the form of partially overlapping fields of view (FOV) combined with a screw adjustment mechanism. A fast image processor-centered LCD driver circuit and an image preprocessing system were also built to address binocular vision inconsistency in the partially overlapping FOV binocular optical system. The distortions of the HMD optical system with a large field of view were measured. Meanwhile, the optical distortions in the display and the trapezoidal distortions introduced during image processing were corrected by a calibration model for reverse rotations and translations. A high-performance not-fully-transparent VR HMD device with high resolution (1920×1080) and large FOV [141.6°(H)×73.08°(V)] was developed. The full field-of-view average value of angular resolution is 18.6 pixels/degree. With the device, high-quality VR simulations can be completed under various scenarios, and the device can be utilized for simulated trainings in aeronautics, astronautics, and other fields with corresponding platforms. The developed device has positive practical significance.
An Airborne A-Band Spectrometer for Remote Sensing Of Aerosol and Cloud Optical Properties
NASA Technical Reports Server (NTRS)
Pitts, Michael; Hostetler, Chris; Poole, Lamont; Holden, Carl; Rault, Didier
2000-01-01
Atmospheric remote sensing with the O2 A-band has a relatively long history, but most of these studies were attempting to estimate surface pressure or cloud-top pressure. Recent conceptual studies have demonstrated the potential of spaceborne high spectral resolution O2 A-band spectrometers for retrieval of aerosol and cloud optical properties. The physical rationale of this new approach is that information on the scattering properties of the atmosphere is embedded in the detailed line structure of the O2 A-band reflected radiance spectrum. The key to extracting this information is to measure the radiance spectrum at very high spectral resolution. Instrument performance requirement studies indicate that, in addition to high spectral resolution, the successful retrieval of aerosol and cloud properties from A-band radiance spectra will also require high radiometric accuracy, instrument stability, and high signal-to-noise measurements. To experimentally assess the capabilities of this promising new remote sensing application, the NASA Langley Research Center is developing an airborne high spectral resolution A-band spectrometer. The spectrometer uses a plane holographic grating with a folded Littrow geometry to achieve high spectral resolution (0.5 cm-1) and low stray light in a compact package. This instrument will be flown in a series of field campaigns beginning in 2001 to evaluate the overall feasibility of this new technique. Results from these campaigns should be particularly valuable for future spaceborne applications of A-band spectrometers for aerosol and cloud retrievals.
Karki, S; Pokharel, M; Suwal, S; Poudel, R
Background The exact role of High resolution computed tomography (HRCT) temporal bone in preoperative assessment of Chronic suppurative otitis media atticoantral disease still remains controversial. Objective To evaluate the role of high resolution computed tomography temporal bone in Chronic suppurative otitis media atticoantral disease and to compare preoperative computed tomographic findings with intra-operative findings. Method Prospective, analytical study conducted among 65 patients with chronic suppurative otitis media atticoantral disease in Department of Radiodiagnosis, Kathmandu University Dhulikhel Hospital between January 2015 to July 2016. The operative findings were compared with results of imaging. The parameters of comparison were erosion of ossicles, scutum, facial canal, lateral semicircular canal, sigmoid and tegmen plate along with extension of disease to sinus tympani and facial recess. Sensitivity, specificity, negative predictive value, positive predictive values were calculated. Result High resolution computed tomography temporal bone offered sensitivity (Se) and specificity (Sp) of 100% for visualization of sigmoid and tegmen plate erosion. The performance of HRCT in detecting malleus (Se=100%, Sp=95.23%), incus (Se=100%,Sp=80.48%) and stapes (Se=96.55%, Sp=71.42%) erosion was excellent. It offered precise information about facial canal erosion (Se=100%, Sp=75%), scutum erosion (Se=100%, Sp=96.87%) and extension of disease to facial recess and sinus tympani (Se=83.33%,Sp=100%). high resolution computed tomography showed specificity of 100% for lateral semicircular canal erosion (Sp=100%) but with low sensitivity (Se=53.84%). Conclusion The findings of high resolution computed tomography and intra-operative findings were well comparable except for lateral semicircular canal erosion. high resolution computed tomography temporal bone acts as a road map for surgeon to identify the extent of disease, plan for appropriate procedure that is required and prepare for potential complications that can be encountered during surgery.
Robust isotropic super-resolution by maximizing a Laplace posterior for MRI volumes
NASA Astrophysics Data System (ADS)
Han, Xian-Hua; Iwamoto, Yutaro; Shiino, Akihiko; Chen, Yen-Wei
2014-03-01
Magnetic resonance imaging can only acquire volume data with finite resolution due to various factors. In particular, the resolution in one direction (such as the slice direction) is much lower than others (such as the in-plane direction), yielding un-realistic visualizations. This study explores to reconstruct MRI isotropic resolution volumes from three orthogonal scans. This proposed super- resolution reconstruction is formulated as a maximum a posterior (MAP) problem, which relies on the generation model of the acquired scans from the unknown high-resolution volumes. Generally, the deviation ensemble of the reconstructed high-resolution (HR) volume from the available LR ones in the MAP is represented as a Gaussian distribution, which usually results in some noise and artifacts in the reconstructed HR volume. Therefore, this paper investigates a robust super-resolution by formulating the deviation set as a Laplace distribution, which assumes sparsity in the deviation ensemble based on the possible insight of the appeared large values only around some unexpected regions. In addition, in order to achieve reliable HR MRI volume, we integrates the priors such as bilateral total variation (BTV) and non-local mean (NLM) into the proposed MAP framework for suppressing artifacts and enriching visual detail. We validate the proposed robust SR strategy using MRI mouse data with high-definition resolution in two direction and low-resolution in one direction, which are imaged in three orthogonal scans: axial, coronal and sagittal planes. Experiments verifies that the proposed strategy can achieve much better HR MRI volumes than the conventional MAP method even with very high-magnification factor: 10.
Resolution analysis of archive films for the purpose of their optimal digitization and distribution
NASA Astrophysics Data System (ADS)
Fliegel, Karel; Vítek, Stanislav; Páta, Petr; Myslík, Jiří; Pecák, Josef; Jícha, Marek
2017-09-01
With recent high demand for ultra-high-definition (UHD) content to be screened in high-end digital movie theaters but also in the home environment, film archives full of movies in high-definition and above are in the scope of UHD content providers. Movies captured with the traditional film technology represent a virtually unlimited source of UHD content. The goal to maintain complete image information is also related to the choice of scanning resolution and spatial resolution for further distribution. It might seem that scanning the film material in the highest possible resolution using state-of-the-art film scanners and also its distribution in this resolution is the right choice. The information content of the digitized images is however limited, and various degradations moreover lead to its further reduction. Digital distribution of the content in the highest image resolution might be therefore unnecessary or uneconomical. In other cases, the highest possible resolution is inevitable if we want to preserve fine scene details or film grain structure for archiving purposes. This paper deals with the image detail content analysis of archive film records. The resolution limit in captured scene image and factors which lower the final resolution are discussed. Methods are proposed to determine the spatial details of the film picture based on the analysis of its digitized image data. These procedures allow determining recommendations for optimal distribution of digitized video content intended for various display devices with lower resolutions. Obtained results are illustrated on spatial downsampling use case scenario, and performance evaluation of the proposed techniques is presented.
NASA Astrophysics Data System (ADS)
Harris, S.; Labahn, J. W.; Frank, J. H.; Ihme, M.
2017-11-01
Data assimilation techniques can be integrated with time-resolved numerical simulations to improve predictions of transient phenomena. In this study, optimal interpolation and nudging are employed for assimilating high-speed high-resolution measurements obtained for an inert jet into high-fidelity large-eddy simulations. This experimental data set was chosen as it provides both high spacial and temporal resolution for the three-component velocity field in the shear layer of the jet. Our first objective is to investigate the impact that data assimilation has on the resulting flow field for this inert jet. This is accomplished by determining the region influenced by the data assimilation and corresponding effect on the instantaneous flow structures. The second objective is to determine optimal weightings for two data assimilation techniques. The third objective is to investigate how the frequency at which the data is assimilated affects the overall predictions. Graduate Research Assistant, Department of Mechanical Engineering.
Study of fish response using particle image velocimetry and high-speed, high-resolution imaging
DOE Office of Scientific and Technical Information (OSTI.GOV)
Deng, Z.; Richmond, M. C.; Mueller, R. P.
2004-10-01
Fish swimming has fascinated both engineers and fish biologists for decades. Digital particle image velocimetry (DPIV) and high-speed, high-resolution digital imaging are recently developed analysis tools that can help engineers and biologists better understand how fish respond to turbulent environments. This report details studies to evaluate DPIV. The studies included a review of existing literature on DPIV, preliminary studies to test the feasibility of using DPIV conducted at our Flow Biology Laboratory in Richland, Washington September through December 2003, and applications of high-speed, high-resolution digital imaging with advanced motion analysis to investigations of fish injury mechanisms in turbulent shear flowsmore » and bead trajectories in laboratory physical models. Several conclusions were drawn based on these studies, which are summarized as recommendations for proposed research at the end of this report.« less
Genome-wide high-resolution aCGH analysis of gestational choriocarcinomas.
Poaty, Henriette; Coullin, Philippe; Peko, Jean Félix; Dessen, Philippe; Diatta, Ange Lucien; Valent, Alexander; Leguern, Eric; Prévot, Sophie; Gombé-Mbalawa, Charles; Candelier, Jean-Jacques; Picard, Jean-Yves; Bernheim, Alain
2012-01-01
Eleven samples of DNA from choriocarcinomas were studied by high resolution CGH-array 244 K. They were studied after histopathological confirmation of the diagnosis, of the androgenic etiology and after a microsatellite marker analysis confirming the absence of contamination of tumor DNA from maternal DNA. Three cell lines, BeWo, JAR, JEG were also studied by this high resolution pangenomic technique. According to aCGH analysis, the de novo choriocarcinomas exhibited simple chromosomal rearrangements or normal profiles. The cell lines showed various and complex chromosomal aberrations. 23 Minimal Critical Regions were defined that allowed us to list the genes that were potentially implicated. Among them, unusually high numbers of microRNA clusters and imprinted genes were observed.
High resolution hard X-ray spectra of solar and cosmic sources. Ph.D. Thesis
NASA Technical Reports Server (NTRS)
Schwartz, R. A.
1984-01-01
High resolution hard X-ray observations of a large solar flare and the Crab Nebula were obtained during balloon flights using an array of cooled germanium planar detectors. In addition, high time resolution high sensitivity measurements were obtained with a 300 square cm NaI/CsI phoswich scintillator. The Crab spectrum from both flights was searched without finding evidence of line emission below 200 keV. In particular, for the 73 keV line previously reported a 3 sigma upper limit for a narrow (1 keV FWHM) line .0019 and .0014 ph square cm/sec for the 1979 and 1980 flights, respectively was obtained.
NASA Astrophysics Data System (ADS)
Mongeon, R. J.
1984-11-01
The beam of a laser radar is moved over the field of view by means of a pair of scanner/trackers arranged in cascade along the laser beam. One of the scanner/trackers operates at high speed, with high resolution and a wide field and is located in the demagnified portion of the laser beam. The two scanner/trackers complement each other to achieve high speed, high resolution scanning as well as tracking of moving targets. A beam steering telescope for an airborne laser radar which incorporates the novel dual mode scanner/tracker is also shown. The other scanner/tracker operates at low speed with low resolution and a wide field and is located in the magnified portion of the laser beam.
High Resolution Infrared Radiation Sounder (HIRS) for the Nimbus F Spacecraft
NASA Technical Reports Server (NTRS)
Koenig, E. W.
1975-01-01
Flown on Nimbus F in June 1975, the high resolution infrared radiation sounder (HIRS) scans with a geographical resolution of 23KM and samples radiance in seventeen selected spectral channels from visible (.7 micron) to far IR (15 micron). Vertical temperature profiles and atmospheric moisture content can be inferred from the output. System operation and test results are described.
ERIC Educational Resources Information Center
Deutsch, Morton
This paper is a summary report of a study of the effects of training in conflict resolution and cooperative learning in an alternative high school in New York City. Three of the school's four campuses participated, with Campus A receiving conflict resolution training, Campus C receiving cooperative learning training, and Campus B receiving…
Gamma-Ray Imager With High Spatial And Spectral Resolution
NASA Technical Reports Server (NTRS)
Callas, John L.; Varnell, Larry S.; Wheaton, William A.; Mahoney, William A.
1996-01-01
Gamma-ray instrument developed to enable both two-dimensional imaging at relatively high spatial resolution and spectroscopy at fractional-photon-energy resolution of about 10 to the negative 3rd power in photon-energy range from 10 keV to greater than 10 MeV. In its spectroscopic aspect, instrument enables identification of both narrow and weak gamma-ray spectral peaks.
L. Arroyo; S.P. Healey; W.B. Cohen; D. Cocero; J.A. Manzanera
2006-01-01
Knowledge of fuel load and composition is critical in fighting, preventing, and understanding wildfires. Commonly, the generation of fuel maps from remotely sensed imagery has made use of medium-resolution sensors such as Landsat. This paper presents a methodology to generate fuel type maps from high spatial resolution satellite data through object-oriented...
NASA Technical Reports Server (NTRS)
Rigney, Matt; Jedlovec, Gary; LaFontaine, Frank; Shafer, Jaclyn
2010-01-01
Heat and moisture exchange between ocean surface and atmosphere plays an integral role in short-term, regional NWP. Current SST products lack both spatial and temporal resolution to accurately capture small-scale features that affect heat and moisture flux. NASA satellite is used to produce high spatial and temporal resolution SST analysis using an OI technique.
High-Resolution Autoradiography
NASA Technical Reports Server (NTRS)
Towe, George C; Gomberg, Henry J; Freemen, J W
1955-01-01
This investigation was made to adapt wet-process autoradiography to metallurgical samples to obtain high resolution of segregated radioactive elements in microstructures. Results are confined to development of the technique, which was perfected to a resolution of less than 10 microns. The radioactive samples included carbon-14 carburized iron and steel, nickel-63 electroplated samples, a powder product containing nickel-63, and tungsten-185 in N-155 alloy.
Pengra, Bruce; Long, Jordan; Dahal, Devendra; Stehman, Stephen V.; Loveland, Thomas R.
2015-01-01
The methodology for selection, creation, and application of a global remote sensing validation dataset using high resolution commercial satellite data is presented. High resolution data are obtained for a stratified random sample of 500 primary sampling units (5 km × 5 km sample blocks), where the stratification based on Köppen climate classes is used to distribute the sample globally among biomes. The high resolution data are classified to categorical land cover maps using an analyst mediated classification workflow. Our initial application of these data is to evaluate a global 30 m Landsat-derived, continuous field tree cover product. For this application, the categorical reference classification produced at 2 m resolution is converted to percent tree cover per 30 m pixel (secondary sampling unit)for comparison to Landsat-derived estimates of tree cover. We provide example results (based on a subsample of 25 sample blocks in South America) illustrating basic analyses of agreement that can be produced from these reference data. Commercial high resolution data availability and data quality are shown to provide a viable means of validating continuous field tree cover. When completed, the reference classifications for the full sample of 500 blocks will be released for public use.
Single-shot spiral imaging at 7 T.
Engel, Maria; Kasper, Lars; Barmet, Christoph; Schmid, Thomas; Vionnet, Laetitia; Wilm, Bertram; Pruessmann, Klaas P
2018-03-25
The purpose of this work is to explore the feasibility and performance of single-shot spiral MRI at 7 T, using an expanded signal model for reconstruction. Gradient-echo brain imaging is performed on a 7 T system using high-resolution single-shot spiral readouts and half-shot spirals that perform dual-image acquisition after a single excitation. Image reconstruction is based on an expanded signal model including the encoding effects of coil sensitivity, static off-resonance, and magnetic field dynamics. The latter are recorded concurrently with image acquisition, using NMR field probes. The resulting image resolution is assessed by point spread function analysis. Single-shot spiral imaging is achieved at a nominal resolution of 0.8 mm, using spiral-out readouts of 53-ms duration. High depiction fidelity is achieved without conspicuous blurring or distortion. Effective resolutions are assessed as 0.8, 0.94, and 0.98 mm in CSF, gray matter and white matter, respectively. High image quality is also achieved with half-shot acquisition yielding image pairs at 1.5-mm resolution. Use of an expanded signal model enables single-shot spiral imaging at 7 T with unprecedented image quality. Single-shot and half-shot spiral readouts deploy the sensitivity benefit of high field for rapid high-resolution imaging, particularly for functional MRI and arterial spin labeling. © 2018 International Society for Magnetic Resonance in Medicine.
Development of a superconducting bulk magnet for NMR and MRI.
Nakamura, Takashi; Tamada, Daiki; Yanagi, Yousuke; Itoh, Yoshitaka; Nemoto, Takahiro; Utumi, Hiroaki; Kose, Katsumi
2015-10-01
A superconducting bulk magnet composed of six vertically stacked annular single-domain c-axis-oriented Eu-Ba-Cu-O crystals was energized to 4.74 T using a conventional superconducting magnet for high-resolution NMR spectroscopy. Shim coils, gradient coils, and radio frequency coils for high resolution NMR and MRI were installed in the 23 mm-diameter room-temperature bore of the bulk magnet. A 6.9 ppm peak-to-peak homogeneous region suitable for MRI was achieved in the central cylindrical region (6.2 mm diameter, 9.1 mm length) of the bulk magnet by using a single layer shim coil. A 21 Hz spectral resolution that can be used for high resolution NMR spectroscopy was obtained in the central cylindrical region (1.3 mm diameter, 4 mm length) of the bulk magnet by using a multichannel shim coil. A clear 3D MR image dataset of a chemically fixed mouse fetus with (50 μm)(3) voxel resolution was obtained in 5.5 h. We therefore concluded that the cryogen-free superconducting bulk magnet developed in this study is useful for high-resolution desktop NMR, MRI and mobile NMR device. Copyright © 2015 Elsevier Inc. All rights reserved.
High-resolution EEG (HR-EEG) and magnetoencephalography (MEG).
Gavaret, M; Maillard, L; Jung, J
2015-03-01
High-resolution EEG (HR-EEG) and magnetoencephalography (MEG) allow the recording of spontaneous or evoked electromagnetic brain activity with excellent temporal resolution. Data must be recorded with high temporal resolution (sampling rate) and high spatial resolution (number of channels). Data analyses are based on several steps with selection of electromagnetic signals, elaboration of a head model and use of algorithms in order to solve the inverse problem. Due to considerable technical advances in spatial resolution, these tools now represent real methods of ElectroMagnetic Source Imaging. HR-EEG and MEG constitute non-invasive and complementary examinations, characterized by distinct sensitivities according to the location and orientation of intracerebral generators. In the presurgical assessment of drug-resistant partial epilepsies, HR-EEG and MEG can characterize and localize interictal activities and thus the irritative zone. HR-EEG and MEG often yield significant additional data that are complementary to other presurgical investigations and particularly relevant in MRI-negative cases. Currently, the determination of the epileptogenic zone and functional brain mapping remain rather less well-validated indications. In France, in 2014, HR-EEG is now part of standard clinical investigation of epilepsy, while MEG remains a research technique. Copyright © 2015 Elsevier Masson SAS. All rights reserved.
A Virtual Study of Grid Resolution on Experiments of a Highly-Resolved Turbulent Plume
NASA Astrophysics Data System (ADS)
Maisto, Pietro M. F.; Marshall, Andre W.; Gollner, Michael J.; Fire Protection Engineering Department Collaboration
2017-11-01
An accurate representation of sub-grid scale turbulent mixing is critical for modeling fire plumes and smoke transport. In this study, PLIF and PIV diagnostics are used with the saltwater modeling technique to provide highly-resolved instantaneous field measurements in unconfined turbulent plumes useful for statistical analysis, physical insight, and model validation. The effect of resolution was investigated employing a virtual interrogation window (of varying size) applied to the high-resolution field measurements. Motivated by LES low-pass filtering concepts, the high-resolution experimental data in this study can be analyzed within the interrogation windows (i.e. statistics at the sub-grid scale) and on interrogation windows (i.e. statistics at the resolved scale). A dimensionless resolution threshold (L/D*) criterion was determined to achieve converged statistics on the filtered measurements. Such a criterion was then used to establish the relative importance between large and small-scale turbulence phenomena while investigating specific scales for the turbulent flow. First order data sets start to collapse at a resolution of 0.3D*, while for second and higher order statistical moments the interrogation window size drops down to 0.2D*.
Huang, Wei; Xiao, Liang; Liu, Hongyi; Wei, Zhihui
2015-01-19
Due to the instrumental and imaging optics limitations, it is difficult to acquire high spatial resolution hyperspectral imagery (HSI). Super-resolution (SR) imagery aims at inferring high quality images of a given scene from degraded versions of the same scene. This paper proposes a novel hyperspectral imagery super-resolution (HSI-SR) method via dictionary learning and spatial-spectral regularization. The main contributions of this paper are twofold. First, inspired by the compressive sensing (CS) framework, for learning the high resolution dictionary, we encourage stronger sparsity on image patches and promote smaller coherence between the learned dictionary and sensing matrix. Thus, a sparsity and incoherence restricted dictionary learning method is proposed to achieve higher efficiency sparse representation. Second, a variational regularization model combing a spatial sparsity regularization term and a new local spectral similarity preserving term is proposed to integrate the spectral and spatial-contextual information of the HSI. Experimental results show that the proposed method can effectively recover spatial information and better preserve spectral information. The high spatial resolution HSI reconstructed by the proposed method outperforms reconstructed results by other well-known methods in terms of both objective measurements and visual evaluation.
A Procedure for High Resolution Satellite Imagery Quality Assessment
Crespi, Mattia; De Vendictis, Laura
2009-01-01
Data products generated from High Resolution Satellite Imagery (HRSI) are routinely evaluated during the so-called in-orbit test period, in order to verify if their quality fits the desired features and, if necessary, to obtain the image correction parameters to be used at the ground processing center. Nevertheless, it is often useful to have tools to evaluate image quality also at the final user level. Image quality is defined by some parameters, such as the radiometric resolution and its accuracy, represented by the noise level, and the geometric resolution and sharpness, described by the Modulation Transfer Function (MTF). This paper proposes a procedure to evaluate these image quality parameters; the procedure was implemented in a suitable software and tested on high resolution imagery acquired by the QuickBird, WorldView-1 and Cartosat-1 satellites. PMID:22412312
THz holography in reflection using a high resolution microbolometer array.
Zolliker, Peter; Hack, Erwin
2015-05-04
We demonstrate a digital holographic setup for Terahertz imaging of surfaces in reflection. The set-up is based on a high-power continuous wave (CW) THz laser and a high-resolution (640 × 480 pixel) bolometer detector array. Wave propagation to non-parallel planes is used to reconstruct the object surface that is rotated relative to the detector plane. In addition we implement synthetic aperture methods for resolution enhancement and compare Fourier transform phase retrieval to phase stepping methods. A lateral resolution of 200 μm and a relative phase sensitivity of about 0.4 rad corresponding to a depth resolution of 6 μm are estimated from reconstructed images of two specially prepared test targets, respectively. We highlight the use of digital THz holography for surface profilometry as well as its potential for video-rate imaging.
Multichannel analyzers at high rates of input
NASA Technical Reports Server (NTRS)
Rudnick, S. J.; Strauss, M. G.
1969-01-01
Multichannel analyzer, used with a gating system incorporating pole-zero compensation, pile-up rejection, and baseline-restoration, achieves good resolution at high rates of input. It improves resolution, reduces tailing and rate-contributed continuum, and eliminates spectral shift.
NASA Technical Reports Server (NTRS)
Cageao, R.; Sander, S.; Blavier, J.; Jiang, Y.; Nemtchinov, V.
2000-01-01
A compact, high resolution Fourier-transform spectrometer for atmospheric near ultraviolet spectroscopy has been installed at the Jet Propulsion Laboratory's Table Mountain Facility (34.4N, 117.7 W, elevation 2290m).
Du, Bing; Liu Aimin; Huang, Yeru
2014-09-01
Polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in soil samples were analyzed by isotope dilution method with high resolution gas chromatography and high resolution mass spectrometry (ID-HRGC/HRMS), and the toxic equivalent quantity (TEQ) were calculated. The impacts of major source of measurement uncertainty are discussed, and the combined relative standard uncertainties were calculated for each 2, 3, 7, 8 substituted con- gener. Furthermore, the concentration, combined uncertainty and expanded uncertainty for TEQ of PCDD/Fs in a soil sample in I-TEF, WHO-1998-TEF and WHO-2005-TEF schemes are provided as an example. I-TEF, WHO-1998-TEF and WHO-2005-TEF are the evaluation schemes of toxic equivalent factor (TEF), and are all currently used to describe 2,3,7,8 sub- stituted relative potencies.
Monitoring Cyanobacteria Bloom in Taihu Lake by High-Resolution Geostationary Satellite GF4
NASA Astrophysics Data System (ADS)
Liu, J.
2018-04-01
The high-resolution remote-sensing satellite, GF4 PMS, of China's geosynchronous earth orbit was successfully launched on December 29, 2015. Its high spatial resolution and high temporal resolution allow GF4 PMS to play a very important role in water environment monitoring, especially in the dynamic monitoring of lake and reservoir cyanobacteria blooms. As GF4 PMS has just been launched, there is still relatively little related research, and the practical application effect of GF4 PMS in the extraction of cyanobacteria blooms remains to be further tested. Therefore, in this study, the method and effect of GF4 PMS application in cyanobacteria bloom monitoring were studied in Taihu. It turned that GF4 PMS can be applied to the dynamic monitoring of the distribution of cyanobacteria blooms in Taihu, thereby finding the temporal and spatial variation of the distribution of cyanobacteria blooms.
NASA Technical Reports Server (NTRS)
Shenk, W. E.; Adler, R. F.; Chesters, D.; Susskind, J.; Uccellini, L.
1984-01-01
The measurements from current and planned geosynchronous satellites provide quantitative estimates of temperature and moisture profiles, surface temperature, wind, cloud properties, and precipitation. A number of significant observation characteristics remain, they include: (1) temperature and moisture profiles in cloudy areas; (2) high vertical profile resolution; (3) definitive precipitation area mapping and precipitation rate estimates on the convective cloud scale; (4) winds from low level cloud motions at night; (5) the determination of convective cloud structure; and (6) high resolution surface temperature determination. Four major new observing capabilities are proposed to overcome these deficiencies: a microwave sounder/imager, a high resolution visible and infrared imager, a high spectral resolution infrared sounder, and a total ozone mapper. It is suggested that the four sensors are flown together and used to support major mesoscale and short range forecasting field experiments.
NASA Astrophysics Data System (ADS)
Jian, Aoqun; Zou, Lu; Tang, Haiquan; Duan, Qianqian; Ji, Jianlong; Zhang, Qianwu; Zhang, Xuming; Sang, Shengbo
2017-06-01
The issue of thermal effects is inevitable for the ultrahigh refractive index (RI) measurement. A biosensor with parallel-coupled dual-microring resonator configuration is proposed to achieve high resolution and free thermal effects measurement. Based on the coupled-resonator-induced transparency effect, the design and principle of the biosensor are introduced in detail, and the performance of the sensor is deduced by simulations. Compared to the biosensor based on a single-ring configuration, the designed biosensor has a 10-fold increased Q value according to the simulation results, thus the sensor is expected to achieve a particularly high resolution. In addition, the output signal of the mathematical model of the proposed sensor can eliminate the thermal influence by adopting an algorithm. This work is expected to have great application potentials in the areas of high-resolution RI measurement, such as biomedical discoveries, virus screening, and drinking water safety.
Nowak, Derek B; Lawrence, A J; Sánchez, Erik J
2010-12-10
We present the development of a versatile spectroscopic imaging tool to allow for imaging with single-molecule sensitivity and high spatial resolution. The microscope allows for near-field and subdiffraction-limited far-field imaging by integrating a shear-force microscope on top of a custom inverted microscope design. The instrument has the ability to image in ambient conditions with optical resolutions on the order of tens of nanometers in the near field. A single low-cost computer controls the microscope with a field programmable gate array data acquisition card. High spatial resolution imaging is achieved with an inexpensive CW multiphoton excitation source, using an apertureless probe and simplified optical pathways. The high-resolution, combined with high collection efficiency and single-molecule sensitive optical capabilities of the microscope, are demonstrated with a low-cost CW laser source as well as a mode-locked laser source.
NASA Astrophysics Data System (ADS)
Mayer, J.; Hugenschmidt, C.; Schreckenbach, K.
2010-09-01
We present a high resolution positron annihilation induced Auger Electron Spectroscopy (PAES) of the CuM 2,3VV-transition with the unprecedented energy resolution of Δ/EE <1%. This energy resolution and the highly intense positron source NEPOMUC enabled us to resolve the double peak structure with PAES for the first time within a measurement time of only 5.5 h. In addition, sub-monolayers of Cu were deposited on Fe- and Pd-samples in order to investigate the surface selectivity of PAES in comparison with EAES. The extremely high surface selectivity of PAES due to the different positron affinity of Cu and Fe lead to the result that with only 0.96 monolayer of Cu on Fe more than 55% of the emitted Auger electrons stem from Cu, whereas with EAES the Cu Auger fraction amounted to less than 6%.
NASA Astrophysics Data System (ADS)
Bai, Ting; Sun, Kaimin; Deng, Shiquan; Chen, Yan
2018-03-01
High resolution image change detection is one of the key technologies of remote sensing application, which is of great significance for resource survey, environmental monitoring, fine agriculture, military mapping and battlefield environment detection. In this paper, for high-resolution satellite imagery, Random Forest (RF), Support Vector Machine (SVM), Deep belief network (DBN), and Adaboost models were established to verify the possibility of different machine learning applications in change detection. In order to compare detection accuracy of four machine learning Method, we applied these four machine learning methods for two high-resolution images. The results shows that SVM has higher overall accuracy at small samples compared to RF, Adaboost, and DBN for binary and from-to change detection. With the increase in the number of samples, RF has higher overall accuracy compared to Adaboost, SVM and DBN.
NASA Astrophysics Data System (ADS)
Schneider, Tapio; Lan, Shiwei; Stuart, Andrew; Teixeira, João.
2017-12-01
Climate projections continue to be marred by large uncertainties, which originate in processes that need to be parameterized, such as clouds, convection, and ecosystems. But rapid progress is now within reach. New computational tools and methods from data assimilation and machine learning make it possible to integrate global observations and local high-resolution simulations in an Earth system model (ESM) that systematically learns from both and quantifies uncertainties. Here we propose a blueprint for such an ESM. We outline how parameterization schemes can learn from global observations and targeted high-resolution simulations, for example, of clouds and convection, through matching low-order statistics between ESMs, observations, and high-resolution simulations. We illustrate learning algorithms for ESMs with a simple dynamical system that shares characteristics of the climate system; and we discuss the opportunities the proposed framework presents and the challenges that remain to realize it.
Mastering high resolution tip-enhanced Raman spectroscopy: towards a shift of perception.
Richard-Lacroix, Marie; Zhang, Yao; Dong, Zhenchao; Deckert, Volker
2017-07-03
Recent years have seen tremendous improvement of our understanding of high resolution reachable in TERS experiments, forcing us to re-evaluate our understanding of the intrinsic limits of this field, but also exposing several inconsistencies. On the one hand, more and more recent experimental results have provided us with clear indications of spatial resolutions down to a few nanometres or even on the subnanometre scale. Moreover, lessons learned from recent theoretical investigations clearly support such high resolutions, and vice versa the obvious theoretical impossibility to evade high resolution from a purely plasmonic point of view. On the other hand, most of the published TERS results still, to date, claim a resolution on the order of tens of nanometres that would be somehow limited by the tip apex, a statement well accepted for the past 2 decades. Overall, this now leads the field to a fundamental question: how can this divergence be justified? The answer to this question brings up an equally critical one: how can this gap be bridged? This review aims at raising a fundamental discussion related to the resolution limits of tip-enhanced Raman spectroscopy, at revisiting our comprehension of the factors limiting it both from a theoretical and an experimental point of view and at providing indications on how to move the field ahead. It is our belief that a much deeper understanding of the real accessible lateral resolution in TERS and the practical factors that limit them will simultaneously help us to fully explore the potential of this technique for studying nanoscale features in organic, inorganic and biological systems, and also to improve both the reproducibility and the accuracy of routine TERS studies. A significant improvement of our comprehension of the accessible resolution in TERS is thus critical for a broad audience, even in certain contexts where high resolution TERS is not the desired outcome.
Added-values of high spatiotemporal remote sensing data in crop yield estimation
NASA Astrophysics Data System (ADS)
Gao, F.; Anderson, M. C.
2017-12-01
Timely and accurate estimation of crop yield before harvest is critical for food market and administrative planning. Remote sensing derived parameters have been used for estimating crop yield by using either empirical or crop growth models. The uses of remote sensing vegetation index (VI) in crop yield modeling have been typically evaluated at regional and country scales using coarse spatial resolution (a few hundred to kilo-meters) data or assessed over a small region at field level using moderate resolution spatial resolution data (10-100m). Both data sources have shown great potential in capturing spatial and temporal variability in crop yield. However, the added value of data with both high spatial and temporal resolution data has not been evaluated due to the lack of such data source with routine, global coverage. In recent years, more moderate resolution data have become freely available and data fusion approaches that combine data acquired from different spatial and temporal resolutions have been developed. These make the monitoring crop condition and estimating crop yield at field scale become possible. Here we investigate the added value of the high spatial and temporal VI for describing variability of crop yield. The explanatory ability of crop yield based on high spatial and temporal resolution remote sensing data was evaluated in a rain-fed agricultural area in the U.S. Corn Belt. Results show that the fused Landsat-MODIS (high spatial and temporal) VI explains yield variability better than single data source (Landsat or MODIS alone), with EVI2 performing slightly better than NDVI. The maximum VI describes yield variability better than cumulative VI. Even though VI is effective in explaining yield variability within season, the inter-annual variability is more complex and need additional information (e.g. weather, water use and management). Our findings augment the importance of high spatiotemporal remote sensing data and supports new moderate resolution satellite missions for agricultural applications.
Cremers, David A; Beddingfield, Alan; Smithwick, Robert; Chinni, Rosemarie C; Jones, C Randy; Beardsley, Burt; Karch, Larry
2012-03-01
The development of field-deployable instruments to monitor radiological, nuclear, and explosive (RNE) threats is of current interest for a number of assessment needs such as the on-site screening of suspect facilities and nuclear forensics. The presence of uranium and plutonium and radiological materials can be determined through monitoring the elemental emission spectrum using relatively low-resolution spectrometers. In addition, uranium compounds, explosives, and chemicals used in nuclear fuel processing (e.g., tributyl-phosphate) can be identified by applying chemometric analysis to the laser-induced breakdown (LIBS) spectrum recorded by these spectrometers. For nuclear forensic applications, however, isotopes of U and Pu and other elements (e.g., H and Li) must also be determined, requiring higher resolution spectrometers given the small magnitude of the isotope shifts for some of these elements (e.g., 25 pm for U and 13 pm for Pu). High-resolution spectrometers will be preferred for several reasons but these must fit into realistic field-based analysis scenarios. To address the need for field instrumentation, we evaluated a previously developed field-deployable hand-held LIBS interrogation probe combined with two relatively new high-resolution spectrometers (λ/Δλ ~75,000 and ~44,000) that have the potential to meet field-based analysis needs. These spectrometers are significantly smaller and lighter in weight than those previously used for isotopic analysis and one unit can provide simultaneous wide spectral coverage and high resolution in a relatively small package. The LIBS interrogation probe was developed initially for use with low resolution compact spectrometers in a person-portable backpack LIBS instrument. Here we present the results of an evaluation of the LIBS probe combined with a high-resolution spectrometer and demonstrate rapid detection of isotopes of uranium and hydrogen and highly enriched samples of (6)Li and (7)Li. © 2012 Society for Applied Spectroscopy
NASA Astrophysics Data System (ADS)
Chandra, Chandrasekar V.; Chen*, Haonan
2015-04-01
Urban flash flood is one of the most commonly encountered hazardous weather phenomena. Unfortunately, the rapid urbanization has made the densely populated areas even more vulnerable to flood risks. Hence, accurate and timely monitoring of rainfall at high spatiotemporal resolution is critical to severe weather warning and civil defense, especially in urban areas. However, it is still challenging to produce high-resolution products based on the large S-band National Weather Service (NWS) Next-Generation Weather Radar (NEXRAD), due to the sampling limitations and Earth curvature effect. Since 2012, the U.S. National Science Foundation Engineering Research Center (NSF-ERC) for Collaborative Adaptive Sensing of the Atmosphere (CASA) has initiated the development of Dallas-Fort Worth (DFW) radar remote sensing network for urban weather hazards mitigation. The DFW urban radar network consists of a combination of high-resolution X-band radars and a standard NWS NEXRAD radar operating at S-band frequency. High-resolution quantitative precipitation estimation (QPE) is one of the major research goals in the deployment of this urban radar network. It has been shown in the literature that the dual-polarization radar techniques can improve the QPE accuracy over traditional single-polarization radars by rendering more measurements to enhance the data quality, providing more information about rain drop size distribution (DSD), and implying more characteristics of different hydrometeor types. This paper will present the real-time dual-polarization CASA DFW QPE system, which is developed via fusion of observations from both the high-resolution X band radar network and the S-band NWS radar. The specific dual-polarization rainfall algorithms at different frequencies (i.e., S- and X-band) will be described in details. In addition, the fusion methodology combining observations at different temporal resolution will be presented. In order to demonstrate the capability of rainfall estimation of the CASA DFW QPE system, rainfall measurements from ground rain gauges will be used for evaluation purposes. This high-resolution QPE system is used for urban flash flood forecasting when coupled with hydrological models.
High-Resolution Surface Reconstruction from Imagery for Close Range Cultural Heritage Applications
NASA Astrophysics Data System (ADS)
Wenzel, K.; Abdel-Wahab, M.; Cefalu, A.; Fritsch, D.
2012-07-01
The recording of high resolution point clouds with sub-mm resolution is a demanding and cost intensive task, especially with current equipment like handheld laser scanners. We present an image based approached, where techniques of image matching and dense surface reconstruction are combined with a compact and affordable rig of off-the-shelf industry cameras. Such cameras provide high spatial resolution with low radiometric noise, which enables a one-shot solution and thus an efficient data acquisition while satisfying high accuracy requirements. However, the largest drawback of image based solutions is often the acquisition of surfaces with low texture where the image matching process might fail. Thus, an additional structured light projector is employed, represented here by the pseudo-random pattern projector of the Microsoft Kinect. Its strong infrared-laser projects speckles of different sizes. By using dense image matching techniques on the acquired images, a 3D point can be derived for almost each pixel. The use of multiple cameras enables the acquisition of a high resolution point cloud with high accuracy for each shot. For the proposed system up to 3.5 Mio. 3D points with sub-mm accuracy can be derived per shot. The registration of multiple shots is performed by Structure and Motion reconstruction techniques, where feature points are used to derive the camera positions and rotations automatically without initial information.
Mohr, Claudia; Huffman, Alex; Cubison, Michael J; Aiken, Allison C; Docherty, Kenneth S; Kimmel, Joel R; Ulbrich, Ingrid M; Hannigan, Michael; Jimenez, Jose L
2009-04-01
Organic aerosol (OA) emissions from motor vehicles, meat-cooking and trash burning are analyzed here using a high-resolution aerosol mass spectrometer (AMS). High resolution data show that aerosols emitted by combustion engines and plastic burning are dominated by hydrocarbon-like organic compounds. Meat cooking and especially paper burning emissions contain significant fractions of oxygenated organic compounds; however, their unit-resolution mass spectral signatures are very similar to those from ambient hydrocarbon-like OA, and very different from the mass spectra of ambient secondary or oxygenated OA (OOA). Thus, primary OA from these sources is unlikelyto be a significant direct source of ambient OOA. There are significant differences in high-resolution tracer m/zs that may be useful for differentiating some of these sources. Unlike in most ambient spectra, all of these sources have low total m/z 44 and this signal is not dominated by the CO2+ ion. All sources have high m/z 57, which is low during high OOA ambient periods. Spectra from paper burning are similar to some types of biomass burning OA, with elevated m/z 60. Meat cooking aerosols also have slightly elevated m/z 60, whereas motor vehicle emissions have very low signal at this m/z.
Fusion of PET and MRI for Hybrid Imaging
NASA Astrophysics Data System (ADS)
Cho, Zang-Hee; Son, Young-Don; Kim, Young-Bo; Yoo, Seung-Schik
Recently, the development of the fusion PET-MRI system has been actively studied to meet the increasing demand for integrated molecular and anatomical imaging. MRI can provide detailed anatomical information on the brain, such as the locations of gray and white matter, blood vessels, axonal tracts with high resolution, while PET can measure molecular and genetic information, such as glucose metabolism, neurotransmitter-neuroreceptor binding and affinity, protein-protein interactions, and gene trafficking among biological tissues. State-of-the-art MRI systems, such as the 7.0 T whole-body MRI, now can visualize super-fine structures including neuronal bundles in the pons, fine blood vessels (such as lenticulostriate arteries) without invasive contrast agents, in vivo hippocampal substructures, and substantia nigra with excellent image contrast. High-resolution PET, known as High-Resolution Research Tomograph (HRRT), is a brain-dedicated system capable of imaging minute changes of chemicals, such as neurotransmitters and -receptors, with high spatial resolution and sensitivity. The synergistic power of the two, i.e., ultra high-resolution anatomical information offered by a 7.0 T MRI system combined with the high-sensitivity molecular information offered by HRRT-PET, will significantly elevate the level of our current understanding of the human brain, one of the most delicate, complex, and mysterious biological organs. This chapter introduces MRI, PET, and PET-MRI fusion system, and its algorithms are discussed in detail.
A Search for Water in a Super-Earth Atmosphere: High-resolution Optical Spectroscopy of 55Cancri e
DOE Office of Scientific and Technical Information (OSTI.GOV)
Esteves, Lisa J.; De Mooij, Ernst J. W.; Watson, Chris
We present the analysis of high-resolution optical spectra of four transits of 55Cnc e, a low-density super-Earth that orbits a nearby Sun-like star in under 18 hr. The inferred bulk density of the planet implies a substantial envelope, which, according to mass–radius relationships, could be either a low-mass extended or a high-mass compact atmosphere. Our observations investigate the latter scenario, with water as the dominant species. We take advantage of the Doppler cross-correlation technique, high-spectral resolution, and the large wavelength coverage of our observations to search for the signature of thousands of optical water absorption lines. Using our observations with HDSmore » on the Subaru telescope and ESPaDOnS on the Canada–France–Hawaii Telescope, we are able to place a 3 σ lower limit of 10 g mol{sup −1} on the mean-molecular weight of 55Cnc e’s water-rich (volume mixing ratio >10%), optically thin atmosphere, which corresponds to an atmospheric scale-height of ∼80 km. Our study marks the first high-spectral resolution search for water in a super-Earth atmosphere, and demonstrates that it is possible to recover known water-vapor absorption signals in a nearby super-Earth atmosphere, using high-resolution transit spectroscopy with current ground-based instruments.« less
NASA Astrophysics Data System (ADS)
Wiati, C. B.; Indriyanti, S. Y.; Maharani, R.; Subarudi
2018-04-01
Conflict resolution in Labanan Research Forest (LRF) by the Dipterocarps Forest Ecosystem Research and Development Center (Balai Besar Penelitian dan Pengembangan Ekosistem Hutan Dipterokarpa – B2P2EHD) needs support from other parties that are also interested in such forest management. This paper aimed to presented conflict resolution in LRF through stakeholder mapping for its engagement. This research was conducted for seven months (June to December 2015) with interviews and literature study as its data collection. Collected data were analysed by a stakeholder analysis and matrix based on their interest and power levels. Two important findings were: (1) There are 19 parties having interests in the existence of LRF should be engaged; (2) Conflict resolution of LRF can be achieved: (a) ensuring key stakeholders which have high interest and high power level has same perception in existence and management of LRF, (b) establishing a partnership with primary stakeholders which have high interest and high power levels; (c) building partnerships between primary stakeholders which have high interest but low power levels, (d) building partnerships between key and secondary stakeholders which have low interest but high power levels and (e) gaining support from primary and secondary stakeholders which have low interest and low power levels. Stakeholder mapping is an important tool for tenure conflict resolution through mapping the power and interest of the conflicted parties and finding the proper parties to be approached.