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Sample records for high-resolution heavy ion

  1. High resolution charge spectroscopy of heavy ions with FNTD technology

    NASA Astrophysics Data System (ADS)

    Bartz, J. A.; Kodaira, S.; Kurano, M.; Yasuda, N.; Akselrod, M. S.

    2014-09-01

    This paper is focused on the improvement of the heavy charge particle charge resolution of Fluorescent Nuclear Track Detector (FNTD) technology. Fluorescent intensity of individual heavy charge particle tracks is used to construct the spectrum. Sources of spectroscopic line broadening were investigated and several fluorescent intensity correction procedures were introduced to improve the charge resolution down to δZ = 0.25 c.u. and enable FNTD technology to distinguish between all projectile fragments of 290 MeV carbon ions. The benefits of using FNTD technology for fragmentation study include large dynamic range and wide angular acceptance. While we describe these developments in the context of fragmentation studies, the same techniques are readily extended to FNTD LET spectroscopy in general.

  2. Development of a High Resolution Analyzing Magnet System for Heavy Molecular Ions

    NASA Astrophysics Data System (ADS)

    Ghazaly, Mohamed O. A. El; Dehnel, Morgan; Defrance, Pierre

    At the King Abdulaziz City for Science and Technology (KACST, Saudi Arabia), a versatile ion-beam injector was constructed to provide the electrostatic storage ring with the required high-quality ion beams. In order to remove the ambiguity over the ion mass due to the exclusive application of electric fields in the set-up, the injector is being equipped with a high resolution mass analyzing magnet. A high resolution Analyzing Magnet System has been designed to provide a singly-charged ion beam of kinetic energy up to 50 keV, mass up to 1500 Amu, and with the mass resolution fixed to Δm/m =1:1500. The system includes specific entrance and exit slits, designed to sustain the required mass resolution. Furthermore, specific focusing and shaping optics have been added upstream and downstream the system, in order to monitor and adapt the shape of the ion beam at the entrance and exit of the system, respectively. The present paper gives an overview on the design of this mass analyzing magnet system together with the upstream/downstream adapting optics.

  3. Detection of heavy metal ions in drinking water using a high-resolution differential surface plasmon resonance sensor.

    PubMed

    Forzani, Erica S; Zhang, Haiqian; Chen, Wilfred; Tao, Nongjian

    2005-03-01

    We have built a high-resolution differential surface plasmon resonance (SPR) sensor for heavy metal ion detection. The sensor surface is divided into a reference and sensing areas, and the difference in the SPR angles from the two areas is detected with a quadrant cell photodetector as a differential signal. In the presence of metal ions, the differential signal changes due to specific binding of the metal ions onto the sensing area coated with properly selected peptides, which provides an accurate real-time measurement and quantification of the metal ions. Selective detection of Cu2+ and Ni2+ in the ppt-ppb range was achieved by coating the sensing surface with peptides NH2-Gly-Gly-His-COOH and NH2-(His)6-COOH. Cu2+ in drinking water was tested using this sensor.

  4. Detection of heavy metal ions in water by high-resolution surface plasmon resonance spectroscopy combined with anodic stripping voltammetry.

    PubMed

    Wang, Shaopeng; Forzani, Erica S; Tao, Nongjian

    2007-06-15

    High-resolution differential surface plasmon resonance (SPR) with anodic stripping voltammetry (ASV) capability has been demonstrated for detecting heavy metal ions in water. Metal ions are electroplated onto the gold SPR sensing surface and are quantitatively detected by stripping voltammetry. Both the SPR angular shift and electrochemical current signal are recorded to identify the type and amount of the metal ions in water. The performance of the combined approach is further enhanced by a differential detection approach. The gold sensor surface is divided into a reference and a sensing area, and the difference in the SPR angles from the two areas is detected with a quadrant cell photodetector as a differential signal. Our system demonstrated quantitative detection of copper, lead, and mercury ions in water from part-per-million to sub-part-per-billion levels with good linearity.

  5. Development of high resolution linear-cut beam position monitor for heavy-ion synchrotron of KHIMA project

    NASA Astrophysics Data System (ADS)

    Hwang, Ji-Gwang; Yang, Tae-Keun; Forck, Peter; Noh, Seon Yeong; Hahn, Garam; Choi, Minkyoo

    2017-04-01

    A beam position monitor with high precision and resolution is required to control the beam trajectory for matching to the injection orbit and acceleration in a heavy-ion synchrotron. It will be also used for measuring the beta function, tune, and chromaticity. Since the bunch length at heavy ion synchrotron is relatively long, a few meters, a boxlike device with plates of typically 20 cm length is used to enhance the signal strength and to get a precise linear dependence with respect to the beam displacement. Especially, the linear-cut beam position monitor is adopted to satisfy the position resolution of 100 μm and accuracy of 200 μm for a nominal beam intensity in the KHIMA synchrotron of ∼ 7 ×108 particles for the carbon beams and ∼ 2 ×1010 for the proton beams. In this paper, we show the electromagnetic design of the electrode and surroundings to satisfy the resolution of 100 μm, the criteria for mechanical aspect to satisfy the position accuracy of 200 μm, the measurement results by using wire test-bench, design and measurement of a high input impedance pre-amplifier, and the beam-test results with long (∼1.6 μs) electron beam in Pohang accelerator laboratory (PAL).

  6. Heavy ion and proton beams in high resolution imaging of a fungi spore specimen using STIM tomography

    NASA Astrophysics Data System (ADS)

    Formenti, P.; Breese, M. B. H.; Connell, S. H.; Doyle, B. P.; Drummond, M. L.; Machi, I. Z.; Maclear, R. D.; Schaaff, P.; Sellschop, J. P. F.; Bench, G.; Sideras-Haddad, E.; Antolak, A.; Morse, D.

    1997-07-01

    Scanning transmission ion microscopy (STIM) tomography as a 3-D imaging technique has been shown to have a range of applications. The energy of the transmitted ion is detected with nearly 100% efficiency as a function of position in the transverse plane. The parameters relating to transmitted ion energy loss in the sample are imaged with statistics given by the energy loss process rather than Poisson counting statistics. This enables very fast collection of a set of relatively noise-free 2-D images. Each image is collected after a small rotation of the sample, and a complete 3-D representation of the sample may be tomographically reconstructed. The small beam currents necessary mean that the technique is non-destructive. One of the fields where these non-destructive 3-D density structure maps are particularly useful is in the analysis of biological tissue. The variation of energy loss with projectile atomic number may be exploited to tune the energy loss contrast to the size and density of the sample (heavy ion STIM). This work develops this point, and applies it to the imaging of the microscopic structure of a 90 μm diameter mycorrhiza fungi spore. This specimen has been imaged non-destructively in 3-D using both a 36 MeV 12C beam and a 2.2 MeV proton beam, both with a spatial resolution of about 1 μm. The gain in contrast in the carbon median energy loss maps was dramatic as expected. The corresponding improvement in the tomogram was found to be visible but less dramatic. The tomographic sections as well as the median energy loss maps of the vesicular-arbuscular mycorrhiza fungi spore clearly show the internal structure. Wall morphology data has relevance to germination behaviour of the spores.

  7. High Resolution Observations of Escaping Ions in the Martian Magnetotail

    NASA Astrophysics Data System (ADS)

    Halekas, J. S.; Raman, C.; Brain, D.; DiBraccio, G. A.; Harada, Y.; McFadden, J. P.; Mitchell, D. L.; Connerney, J. E. P.; Jakosky, B. M.

    2016-12-01

    Ions escape from the Martian upper atmosphere via a number of channels, including the central plasmasheet of the magnetotail. Mars Express observations show that the heavy ions O+ and O2+ escaping through the central tail often have approximately the same energy, suggesting acceleration in a quasi-static electric field, which has been interpreted as a Hall electric field. The Solar Wind Ion Analyzer (SWIA) on MAVEN was designed to measure the upstream solar wind. However, during orbit segments with appropriate spacecraft attitude, SWIA can also make high resolution measurements of escaping ions in the tail. During the prime mission, these observations were only returned sporadically, during periods of intense escaping fluxes that fortuitously triggered a mode switch. Now, in the extended mission, we return high resolution observations from SWIA routinely. Some of these high resolution measurements reveal slight differences in both the direction and energy of escaping O+ and O2+ ions, which may help determine the acceleration process(es). We investigate the location and solar wind conditions for which the escaping ions separate in energy and angle and the systematics of their energies and flow vectors, and discuss the implications for ion acceleration and the overall picture of Martian atmospheric escape.

  8. Heavy-ion radiotherapy

    NASA Astrophysics Data System (ADS)

    Kanai, Tatsuaki

    2000-11-01

    Heavy-ion radiotherapy using high-energy carbon beams has been performed at the National Institute of Radiological Sciences, Japan. The physical frame works for heavy-ion radiotherapy are established using physical understandings of radiation physics. In order to increase the accuracy of heavy-ion radiotherapy, many physical problems should be solved. Unsolved problems, such as the depth dose distributions, range of heavy-ion in patients and heavy-ion dosimetry in the radiation therapy, are discussed. .

  9. Accelerated High-Resolution Differential Ion Mobility Separations Using Hydrogen

    PubMed Central

    Shvartsburg, Alexandre A.; Smith, Richard D.

    2011-01-01

    The resolving power of differential ion mobility spectrometry (FAIMS) was dramatically increased recently by carrier gases comprising up to 75% He or various vapors, enabling many new applications. However, the need for resolution of complex mixtures is virtually open-ended and many topical analyses demand yet finer separations. Also, the resolving power gains are often at the expense of speed, in particular making high-resolution FAIMS incompatible with online liquid-phase separations. Here, we report FAIMS employing hydrogen, specifically in mixtures with N2 containing up to 90% H2. Such compositions raise the mobilities of all ions and thus the resolving power beyond that previously feasible, while avoiding the electrical breakdown inevitable in He-rich mixtures. The increases in resolving power and ensuing peak resolution are especially significant at H2 fractions above ~50%. Higher resolution can be exchanged for acceleration of the analyses by up to ~4 times, at least. For more mobile species such as multiply-charged peptides, this exchange is presently forced by the constraints of existing FAIMS devices, but future designs optimized for H2 should consistently improve resolution for all analytes. PMID:22074292

  10. High Resolution Helium Ion Scanning Microscopy of the Rat Kidney

    PubMed Central

    Rice, William L.; Van Hoek, Alfred N.; Păunescu, Teodor G.; Huynh, Chuong; Goetze, Bernhard; Singh, Bipin; Scipioni, Larry; Stern, Lewis A.; Brown, Dennis

    2013-01-01

    Helium ion scanning microscopy is a novel imaging technology with the potential to provide sub-nanometer resolution images of uncoated biological tissues. So far, however, it has been used mainly in materials science applications. Here, we took advantage of helium ion microscopy to explore the epithelium of the rat kidney with unsurpassed image quality and detail. In addition, we evaluated different tissue preparation methods for their ability to preserve tissue architecture. We found that high contrast, high resolution imaging of the renal tubule surface is possible with a relatively simple processing procedure that consists of transcardial perfusion with aldehyde fixatives, vibratome tissue sectioning, tissue dehydration with graded methanol solutions and careful critical point drying. Coupled with the helium ion system, fine details such as membrane texture and membranous nanoprojections on the glomerular podocytes were visualized, and pores within the filtration slit diaphragm could be seen in much greater detail than in previous scanning EM studies. In the collecting duct, the extensive and striking apical microplicae of the intercalated cells were imaged without the shrunken or distorted appearance that is typical with conventional sample processing and scanning electron microscopy. Membrane depressions visible on principal cells suggest possible endo- or exocytotic events, and central cilia on these cells were imaged with remarkable preservation and clarity. We also demonstrate the use of colloidal gold probes for highlighting specific cell-surface proteins and find that 15 nm gold labels are practical and easily distinguishable, indicating that external labels of various sizes can be used to detect multiple targets in the same tissue. We conclude that this technology represents a technical breakthrough in imaging the topographical ultrastructure of animal tissues. Its use in future studies should allow the study of fine cellular details and provide

  11. High resolution helium ion scanning microscopy of the rat kidney.

    PubMed

    Rice, William L; Van Hoek, Alfred N; Păunescu, Teodor G; Huynh, Chuong; Goetze, Bernhard; Singh, Bipin; Scipioni, Larry; Stern, Lewis A; Brown, Dennis

    2013-01-01

    Helium ion scanning microscopy is a novel imaging technology with the potential to provide sub-nanometer resolution images of uncoated biological tissues. So far, however, it has been used mainly in materials science applications. Here, we took advantage of helium ion microscopy to explore the epithelium of the rat kidney with unsurpassed image quality and detail. In addition, we evaluated different tissue preparation methods for their ability to preserve tissue architecture. We found that high contrast, high resolution imaging of the renal tubule surface is possible with a relatively simple processing procedure that consists of transcardial perfusion with aldehyde fixatives, vibratome tissue sectioning, tissue dehydration with graded methanol solutions and careful critical point drying. Coupled with the helium ion system, fine details such as membrane texture and membranous nanoprojections on the glomerular podocytes were visualized, and pores within the filtration slit diaphragm could be seen in much greater detail than in previous scanning EM studies. In the collecting duct, the extensive and striking apical microplicae of the intercalated cells were imaged without the shrunken or distorted appearance that is typical with conventional sample processing and scanning electron microscopy. Membrane depressions visible on principal cells suggest possible endo- or exocytotic events, and central cilia on these cells were imaged with remarkable preservation and clarity. We also demonstrate the use of colloidal gold probes for highlighting specific cell-surface proteins and find that 15 nm gold labels are practical and easily distinguishable, indicating that external labels of various sizes can be used to detect multiple targets in the same tissue. We conclude that this technology represents a technical breakthrough in imaging the topographical ultrastructure of animal tissues. Its use in future studies should allow the study of fine cellular details and provide

  12. In situ measurement of ions parameters of laser produced ion source using high resolution Thomson Parabola Spectrometer

    NASA Astrophysics Data System (ADS)

    Chaurasia, S.; Kaur, C.; Rastogi, V.; Poswal, A. K.; Munda, D. S.; Bhatia, R. K.; Nataraju, V.

    2016-08-01

    The laser produced plasma based heavy ion source has become an outstanding front end for heavy ion accelerators. Before being implemented in the heavy ion accelerators its detailed characterization is required. For this purpose, a high resolution and high dispersion Thomson parabola spectrometer comprising of Time-of-Flight diagnostics has been developed for the characterization of ions with energy in the range from 1 keV to 1 MeV/nucleon and incorporated in the Laser plasma experimental chamber. The ion spectrometer is optimized with graphite target. The carbon ions of charge states C1+ to C6+ are observed in the energy range from 3 keV to 300 keV, which has also been verified by Time-of-Flight measurement. Experimental results were matched with simulation done by SIMION 7.0 code which is used for the design of the spectrometer. We also developed data analysis software using Python language to measure in situ ion's parameters and the results are in better agreement to the experimental results than the commercially available software SIMION 7.0. The resolution of the spectrometer is ΔE/E = 0.026 @ 31 keV for charge state (C4+) of carbon.

  13. High-resolution excitation of ions in a low-pressure linear ion trap.

    PubMed

    Collings, B A

    2011-01-15

    An exploration of the parameters necessary to obtain high-resolution excitation, using dipolar excitation, of an ion in a linear ion trap has been undertaken in this study. These parameters included ion trap pressure, excitation amplitude, excitation period, drive frequency of the ion trap, Mathieu q value and the mass of the ion of interest. An understanding of how these parameters play a role in high-resolution excitation is necessary to the development of a method for the targeted tandem mass spectrometric (MS/MS) analysis of ions with the same nominal mass. Resonance excitation profiles with full width half maxima as narrow as 0.015 m/z units could be obtained, under the right conditions, for an ion from a homogenously substituted triazatriphosphorine at m/z 322.049, which translates into a mass resolution of >21 500. In this particular case the requirement for high resolution was a low trap pressure (3.8 × 10(-5) Torr), low excitation amplitude (3 mV), long excitation period (100 ms) and a high Mathieu q value(0.8) when using a drive frequency of 1.228 MHz. Similar conditions were used to demonstrate the isolation of individual [M + H](+) component ions from mixtures of bromazepam (m/z 316.008)/chlorprothixene (m/z 316.0921)/fendiline (m/z 316.206) and chlorprothixene (m/z 316.0921)/oxycodone (m/z 316.1543)/fendiline (m/z 316.206) prior to obtaining product ion spectra with excitation at q = 0.236. In the former mixture the individual components were isolated with near 100% efficiency while in the latter mixture the isolation efficiency dropped to near 50% for the oxycodone component and to 80% for the other components.

  14. High Resolution Studies of Heavy NO(y) Molecules in Atmospheric Spectra

    NASA Technical Reports Server (NTRS)

    Goldman, A.; Rinsland, C. P.; Blatherwick, R. D.; Murcray, F. J.; Murcray, D. G.

    1994-01-01

    New line parameters for two heavy odd nitrogen molecules HNO3 in the upsilon(sub 5)/2upsilon(sub 9) region, and ClONO2 in the upsilon(sub 4) region are incorporated in the analysis of high resolution i.r. atmospheric spectra. The line parameters arc tested and renormalized vs laboratory spectra, and then applied to retrievals from balloon-borne and ground-based solar absorption spectra.

  15. High-resolution Thomson parabola for ion analysis

    NASA Astrophysics Data System (ADS)

    Cobble, J. A.; Flippo, K. A.; Offermann, D. T.; Lopez, F. E.; Oertel, J. A.; Mastrosimone, D.; Letzring, S. A.; Sinenian, N.

    2011-11-01

    A new, versatile Thomson parabola ion energy (TPIE) analyzer has been designed, constructed, and used at the OMEGA-EP facility. Laser-accelerated multi-MeV ions from hemispherical C targets are transmitted through a W pinhole into a multi-kG magnetic field and subsequently through a parallel electric field of up to 25 kV/cm. The ion drift region has a user-selected length of 10, 50, or 80 cm. With the highest fields, 400-MeV C6+ and C5+ may be resolved. TPIE is ten-inch manipulator (TIM)-mounted at OMEGA-EP and can be used opposite either of the EP ps beams. The instrument runs on pressure-interlocked 15-Vdc power available in EP TIM carts. Flux control derives from the insertion depth into the target chamber and the user-selected pinhole dimensions. The detector consists of CR39 backed by an image plate. A fully relativistic simulation code for calculating ion trajectories was employed for design optimization. Excellent agreement of code predictions with the actual ion positions on the detectors is observed. Through pit counting of carbon-ion tracks in CR39, it is shown that conversion efficiency of laser light to energetic carbon ions exceeds ˜5% for these targets.

  16. High-resolution Thomson parabola for ion analysis.

    PubMed

    Cobble, J A; Flippo, K A; Offermann, D T; Lopez, F E; Oertel, J A; Mastrosimone, D; Letzring, S A; Sinenian, N

    2011-11-01

    A new, versatile Thomson parabola ion energy (TPIE) analyzer has been designed, constructed, and used at the OMEGA-EP facility. Laser-accelerated multi-MeV ions from hemispherical C targets are transmitted through a W pinhole into a multi-kG magnetic field and subsequently through a parallel electric field of up to 25 kV/cm. The ion drift region has a user-selected length of 10, 50, or 80 cm. With the highest fields, 400-MeV C(6+) and C(5+) may be resolved. TPIE is ten-inch manipulator (TIM)-mounted at OMEGA-EP and can be used opposite either of the EP ps beams. The instrument runs on pressure-interlocked 15-Vdc power available in EP TIM carts. Flux control derives from the insertion depth into the target chamber and the user-selected pinhole dimensions. The detector consists of CR39 backed by an image plate. A fully relativistic simulation code for calculating ion trajectories was employed for design optimization. Excellent agreement of code predictions with the actual ion positions on the detectors is observed. Through pit counting of carbon-ion tracks in CR39, it is shown that conversion efficiency of laser light to energetic carbon ions exceeds ~5% for these targets. © 2011 American Institute of Physics

  17. High resolution ion Doppler spectroscopy at Prairie View Rotamak

    SciTech Connect

    Houshmandyar, Saeid; Yang Xiaokang; Magee, Richard

    2012-10-15

    A fast ion Doppler spectroscopy (IDS) diagnostic system is installed on the Prairie View Rotamak to measure ion temperature and plasma flow. The diagnostic employs a single channel photomultiplier tube and a Jarrell-Ash 50 monochromator with a diffraction grating line density of 1180 lines/mm, which allows for first order spectra of 200-600 nm. The motorized gear of the monochromator allows spectral resolution of 0.01 nm. Equal IDS measurements are observed for various impurity emission lines of which carbon lines exhibit stronger intensities. Furthermore, the diagnostics is examined in an experiment where plasma experiences sudden disruption and quick recovery. In this case, the IDS measurements show {approx}130% increase in ion temperature. Flow measurements are shown to be consistent with plasma rotation.

  18. Heavy-ion dosimetry

    SciTech Connect

    Schimmerling, W.

    1980-03-01

    This lecture deals with some of the more important physical characteristics of relativistic heavy ions and their measurement, with beam delivery and beam monitoring, and with conventional radiation dosimetry as used in the operation of the BEVALAC biomedical facility for high energy heavy ions (Lyman and Howard, 1977; BEVALAC, 1977). Even so, many fundamental aspects of the interaction of relativistic heavy ions with matter, including important atomic physics and radiation chemical considerations, are not discussed beyond the reminder that such additional understanding is required before an adequte perspective of the problem can be attained.

  19. A high resolution ion microscope for cold atoms

    NASA Astrophysics Data System (ADS)

    Stecker, Markus; Schefzyk, Hannah; Fortágh, József; Günther, Andreas

    2017-04-01

    We report on an ion-optical system that serves as a microscope for ultracold ground state and Rydberg atoms. The system is designed to achieve a magnification of up to 1000 and a spatial resolution in the 100 nm range, thereby surpassing many standard imaging techniques for cold atoms. The microscope consists of four electrostatic lenses and a microchannel plate in conjunction with a delay line detector in order to achieve single particle sensitivity with high temporal and spatial resolution. We describe the design process of the microscope including ion-optical simulations of the imaging system and characterize aberrations and the resolution limit. Furthermore, we present the experimental realization of the microscope in a cold atom setup and investigate its performance by patterned ionization with a structure size down to 2.7 μm. The microscope meets the requirements for studying various many-body effects, ranging from correlations in cold quantum gases up to Rydberg molecule formation.

  20. High-Resolution Laser Spectroscopy on the Negative Osmium Ion

    SciTech Connect

    Warring, U.; Amoretti, M.; Canali, C.; Fischer, A.; Heyne, R.; Meier, J. O.; Morhard, Ch.; Kellerbauer, A.

    2009-01-30

    We have applied a combination of laser excitation and electric-field detachment to negative atomic ions for the first time, resulting in an enhancement of the excited-state detection efficiency for spectroscopy by at least 2 orders of magnitude. Applying the new method, a measurement of the bound-bound electric-dipole transition frequency in {sup 192}Os{sup -} was performed using collinear spectroscopy with a narrow-bandwidth cw laser. The transition frequency was found to be 257.831 190(35) THz [wavelength 1162.747 06(16) nm, wave number 8600.3227(12) cm{sup -1}], in agreement with the only prior measurement, but with more than 100-fold higher precision.

  1. High resolution EUV spectroscopy of xenon ions with a compact electron beam ion trap

    NASA Astrophysics Data System (ADS)

    Ali, Safdar; Nakamura, Nobuyuki

    2017-09-01

    We performed high resolution extreme ultraviolet (EUV) spectroscopy measurements of highly charged xenon ions with a compact electron beam ion trap. The spectra were recorded with a flat-field grazing incidence spectrometer while varying the electron beam energy between 200 and 890 eV. We measured the wavelengths for several lines of Rh-like Xe9+ - Cd-like Xe6+ and Cu-like Xe25+- Se-like Xe20+ in the range of 150-200 Å with an uncertainty of 0.05 Å. Previously, most of these lines have been reported from EBITs with a wavelength uncertainty of 0.2 Å. Additionally, based on the electron beam energy dependence of the observed spectra we tentatively identified three new lines, which were reported as unidentified lines in the previous studies.

  2. [Distribution and migration of heavy metals in soil profiles by high-resolution sampling].

    PubMed

    Ruan, Xin-ling; Zhang, Gan-lin; Zhao, Yu-guo; Yuan, Da-gang; Wu, Yun-jin

    2006-05-01

    The vertical distribution of heavy metals in soils profiles is a result of heavy metals accumulation and migration under combining influence of edaphic factors and environmental conditions. It's an important basis for evaluation of heavy metals pollution and remediation of contaminated soils. By traditional sampling methods, i.e., soils were sampled according to pedogenetic horizons, only very general information about element migration can be learned. In the current study, three sites near a steel factory were selected to represent three types of land use, i.e. forest, dry land for vegetable cultivation and rice paddy field. Soils were sampled horizontally by high-resolution sampling method. In the top of 40 cm soils were sectioned in 2 cm intervals, then 5 cm intervals in next 40 cm, and 10 cm intervals in the last 20 cm of profile. Total content of Cu, Zn, Pb, Cr and Cd were determined, and the vertical distribution of Cu, Zn, Pb, Cr, Cd in every profile was analyzed. The results indicated that enrichment of heavy metals appeared in the upper most layer of the natural forest soil that without any anthropic disturbance, and this phenomenon proved that heavy metals were coming from atmospheric deposition. We found that Cu, Zn and Pb moved downward in a short distance, Cd migrated relatively faster than Cu, Zn and Pb, while Cr had no recognizable location of migration front. In the soil profiles of dry land and paddy field, there were influences of agricultural practice, the distribution and movement of metals were thus different form those of the forest soil. In cultivated layer heavy metals were evenly distributed because soils in the upper layer were mixed by cultivation, however, bellow the cultivated layer obvious migration took place again. It is concluded that different heavy metals have different mobility and there is such a relative order: Cd>Cu>Zn>Pb. The study shows that the distribution pattern can be obtained with the currently adopted high-resolution

  3. Heavy ion storage rings

    SciTech Connect

    Schuch, R.

    1987-01-01

    A brief overview of synchrotron storage rings for heavy ions, which are presently under construction in different accelerator laboratories is given. Ions ranging from protons up to uranium ions at MeV/nucleon energies will be injected into these rings using multiturn injection from the accelerators available or being built in these laboratories. After injection, it is planned to cool the phase space distribution of the ions by merging them with cold electron beams or laser beams, or by using stochastic cooling. Some atomic physics experiments planned for these rings are presented.

  4. Electrostatic ion trap and Fourier transform measurements for high-resolution mass spectrometry.

    PubMed

    Bhushan, K G; Gadkari, S C; Yakhmi, J V; Sahni, V C

    2007-08-01

    We report on the development of an electrostatic ion trap for high-resolution mass spectrometry. The trap works on purely electrostatic fields and hence trapping and storing of ions is not mass restrictive, unlike other techniques based on Penning, Paul, or radio frequency quadrupole ion traps. It allows simultaneous trapping and studying of multiple mass species over a large mass range. Mass spectra were recorded in "dispersive" and "self-bunching" modes of ions. Storage lifetimes of about 100 ms and mass resolving power of about 20,000 could be achieved from the fifth harmonic Fourier transform spectrum of Xe ions recorded in the self-bunching mode.

  5. HEAVY ION LINEAR ACCELERATOR

    DOEpatents

    Van Atta, C.M.; Beringer, R.; Smith, L.

    1959-01-01

    A linear accelerator of heavy ions is described. The basic contributions of the invention consist of a method and apparatus for obtaining high energy particles of an element with an increased charge-to-mass ratio. The method comprises the steps of ionizing the atoms of an element, accelerating the resultant ions to an energy substantially equal to one Mev per nucleon, stripping orbital electrons from the accelerated ions by passing the ions through a curtain of elemental vapor disposed transversely of the path of the ions to provide a second charge-to-mass ratio, and finally accelerating the resultant stripped ions to a final energy of at least ten Mev per nucleon.

  6. Heavy-ion radiography and heavy-ion computed tomography

    SciTech Connect

    Fabrikant, J.I.; Holley, W.R.; McFarland, E.W.; Tobias, C.a.

    1982-02-01

    Heavy-ion projection and CT radiography is being developed into a safe, low-dose, noninvasive radiological procedure that can quantitate and image small density differences in human tissues. The applications to heavy-ion mammography and heavy-ion CT imaging of the brain in clinical patients suggest their potential value in cancer diagnosis.

  7. Helium ion microscopy for high-resolution visualization of the articular cartilage collagen network.

    PubMed

    Vanden Berg-Foels, W S; Scipioni, L; Huynh, C; Wen, X

    2012-05-01

    The articular cartilage collagen network is an important research focus because network disruption results in cartilage degeneration and patient disability. The recently introduced helium ion microscope (HIM), with its smaller probe size, longer depth of field and charge neutralization, has the potential to overcome the inherent limitations of electron microscopy for visualization of collagen network features, particularly at the nanoscale. In this study, we evaluated the capabilities of the helium ion microscope for high-resolution visualization of the articular cartilage collagen network. Images of rabbit knee cartilage were acquired with a helium ion microscope; comparison images were acquired with a field emission scanning electron microscope (FE-SEM) and a transmission electron microscope (TEM). Sharpness of example high-resolution helium ion microscope and field emission scanning electron microscope images was quantified using the 25-75% rise distance metric. The helium ion microscope was able to acquire high-resolution images with unprecedented clarity, with greater sharpness and three-dimensional-like detail of nanoscale fibril morphologies and fibril connections, in samples without conductive coatings. These nanoscale features could not be resolved by field emission scanning electron microscopy, and three-dimensional network structure could not be visualized with transmission electron microscopy. The nanoscale three-dimensional-like visualization capabilities of the helium ion microscope will enable new avenues of investigation in cartilage collagen network research. © 2012 The Authors Journal of Microscopy © 2012 Royal Microscopical Society.

  8. New high-resolution electrostatic ion mass analyzer using time of flight

    NASA Technical Reports Server (NTRS)

    Hamilton, D. C.; Gloeckler, G.; Ipavich, F. M.; Lundgren, R. A.; Sheldon, R. B.

    1990-01-01

    The design of a high-resolution ion-mass analyzer is described, which is based on an accurate measurement of the time of flight (TOF) of ions within a region configured to produce a harmonic potential. In this device, the TOF, which is independent of ion energy, is determined from a start pulse from secondary electrons produced when the ion passes through a thin carbon foil at the entrance of the TOF region and at a stop pulse from the ion striking a microchannel plate upon exciting the region. A laboratory prototype instrument called 'VMASS' was built and was tested at the Goddard Space Flight Center electrostatic accelerator, showing a good mass resolution of the instrument. Sensors of the VMASS type will form part of the WIND Solar Wind and Suprathermal Ion experiment, the Soho mission, and the Advanced Composition Explorer.

  9. High Resolution Studies of the Origins of Polyatomic Ions in Inductively Coupled Plasma-Mass Spectrometry

    SciTech Connect

    Ferguson, Jill Wisnewski

    2006-01-01

    The inductively coupled plasma (ICP) is an atmospheric pressure ionization source. Traditionally, the plasma is sampled via a sampler cone. A supersonic jet develops behind the sampler, and this region is pumped down to a pressure of approximately one Torr. A skimmer cone is located inside this zone of silence to transmit ions into the mass spectrometer. The position of the sampler and skimmer cones relative to the initial radiation and normal analytical zones of the plasma is key to optimizing the useful analytical signal [1]. The ICP both atomizes and ionizes the sample. Polyatomic ions form through ion-molecule interactions either in the ICP or during ion extraction [l]. Common polyatomic ions that inhibit analysis include metal oxides (MO+), adducts with argon, the gas most commonly used to make up the plasma, and hydride species. While high resolution devices can separate many analytes from common interferences, this is done at great cost in ion transmission efficiency--a loss of 99% when using high versus low resolution on the same instrument [2]. Simple quadrupole devices, which make up the bulk of ICP-MS instruments in existence, do not present this option. Therefore, if the source of polyatomic interferences can be determined and then manipulated, this could potentially improve the figures of merit on all ICP-MS devices, not just the high resolution devices often utilized to study polyatomic interferences.

  10. High resolution morphology and electrical characterization of aged Li-ion battery cathode.

    PubMed

    Ramdon, Sanjay; Bhushan, Bharat

    2012-08-15

    Understanding the changes that take place in an aged Lithium-ion (Li-ion) battery cathode is vital to improving battery storage capabilities. High resolution imaging using an atomic force microscope (AFM) and current measurement capabilities are used to determine the difference in surface morphology as well as conductance between unaged and aged cathode. Upon aging, agglomeration of LiFePO(4) particles with nanocrystalline deposits is observed and the samples show lower conductance and hence increased resistance. The data identifies potential degradation mechanisms which reduce the conductivity of the cathode leading to poor cycling performance of the battery.

  11. Lipid and Glycolipid Isomer Analyses Using Ultra-High Resolution Ion Mobility Spectrometry Separations

    SciTech Connect

    Wojcik, Roza; Webb, Ian; Deng, Liulin; Garimella, Sandilya; Prost, Spencer; Ibrahim, Yehia; Baker, Erin; Smith, Richard

    2017-01-01

    Understanding the biological mechanisms related to lipids and glycolipids is challenging due to the vast number of possible isomers. Mass spectrometry (MS) measurements are currently the dominant approach for studying and providing detailed information on lipid and glycolipid structures. However, difficulties in distinguishing many structural isomers (e.g. distinct acyl chain positions, double bond locations, as well as glycan isomers) inhibit the understanding of their biological roles. Here we utilized ultra-high resolution ion mobility spectrometry (IMS) separations based upon the use of traveling waves in a serpentine long path length multi-pass Structures for Lossless Manipulations (SLIM) to enhance isomer resolution. The multi-pass arrangement allowed separations ranging from ~16 m (1 pass) to ~470 m (32 passes) to be investigated for the distinction of lipids and glycolipids with extremely small structural differences. These ultra-high resolution SLIM IMS-MS analyses provide a foundation for exploring and better understanding isomer specific biological and disease processes.

  12. High-resolution spectrograms of ion acoustic waves in the solar wind

    NASA Technical Reports Server (NTRS)

    Kurth, W. S.; Gurnett, D. A.; Scarf, F. L.

    1979-01-01

    High-resolution, frequency-time spectrograms of ion acoustic waves in the solar wind obtained by the Voyager spacecraft at distances of up to 1.7 AU are examined. The plasma wave instrument on board the Voyager spacecraft used to acquire the spectra employs an electric dipole antenna with a 16-channel step frequency receiver and a high-bit-rate waveform receiver to detect and measure the electric field of plasma waves. Voyager spectrograms show that the ion acoustic waves consist of narrowband, rapidly varying bursts, lasting a few seconds or less, usually in the range between the plasma ion and electron frequencies. Spectrograms taken at 1.7 AU are shown to be essentially identical to similar measurements taken upstream of the earth's magnetosphere, which are produced by suprathermal protons streaming into the solar wind from the bow shock, and to those taken upstream of interplanetary shocks.

  13. High Resolution Separations and Improved Ion Production and Transmission in Metabolomics

    PubMed Central

    Metz, Thomas O.; Page, Jason S.; Baker, Erin S.; Tang, Keqi; Ding, Jie; Shen, Yufeng; Smith, Richard D.

    2008-01-01

    The goal of metabolomics analyses is the detection and quantitation of as many sample components as reasonably possible in order to identify compounds or “features” that can be used to characterize the samples under study. When utilizing electrospray ionization to produce ions for analysis by mass spectrometry (MS), it is important that metabolome sample constituents be efficiently separated prior to ion production, in order to minimize ionization suppression and thereby extend the dynamic range of the measurement, as well as the coverage of the metabolome. Similarly, optimization of the MS inlet and interface can lead to increased measurement sensitivity. This perspective review will focus on the role of high resolution liquid chromatography (LC) separations in conjunction with improved ion production and transmission for LC-MS-based metabolomics. Additional emphasis will be placed on the compromise between metabolome coverage and sample analysis throughput. PMID:19255623

  14. Ion Mobility Spectrometry - High Resolution LTQ-Orbitrap Mass Spectrometry for Analysis of Homemade Explosives

    NASA Astrophysics Data System (ADS)

    Hagan, Nathan; Goldberg, Ilana; Graichen, Adam; St. Jean, Amanda; Wu, Ching; Lawrence, David; Demirev, Plamen

    2017-08-01

    The detailed chemical characterization of homemade explosives (HMEs) and other chemicals that can mimic or mask the presence of explosives is important for understanding and improving the performance of commercial instrumentation used for explosive detection. To that end, an atmospheric-pressure drift tube ion mobility spectrometry (IMS) instrument has been successfully coupled to a commercial tandem mass spectrometry (MS) system. The tandem MS system is comprised of a linear ion trap and a high resolution Orbitrap analyzer. This IMS-MS combination allows extensive characterization of threat chemical compounds, including HMEs, and complex real-world background chemicals that can interfere with detection. Here, the composition of ion species originating from a specific HME, erythritol tetranitrate, has been elucidated using accurate mass measurements, isotopic ratios, and tandem MS. Gated IMS-MS and high-resolution MS have been used to identify minor impurities that can be indicative of the HME source and/or synthesis route. Comparison between data obtained on the IMS/MS system and on commercial stand-alone IMS instruments used as explosive trace detectors (ETDs) has also been performed. Such analysis allows better signature assignments of threat compounds, modified detection algorithms, and improved overall ETD performance.

  15. A simple and rapid method for high-resolution visualization of single-ion tracks

    SciTech Connect

    Omichi, Masaaki; Choi, Wookjin; Sakamaki, Daisuke; Seki, Shu; Tsukuda, Satoshi; Sugimoto, Masaki

    2014-11-15

    Prompt determination of spatial points of single-ion tracks plays a key role in high-energy particle induced-cancer therapy and gene/plant mutations. In this study, a simple method for the high-resolution visualization of single-ion tracks without etching was developed through the use of polyacrylic acid (PAA)-N, N’-methylene bisacrylamide (MBAAm) blend films. One of the steps of the proposed method includes exposure of the irradiated films to water vapor for several minutes. Water vapor was found to promote the cross-linking reaction of PAA and MBAAm to form a bulky cross-linked structure; the ion-track scars were detectable at a nanometer scale by atomic force microscopy. This study demonstrated that each scar is easily distinguishable, and the amount of generated radicals of the ion tracks can be estimated by measuring the height of the scars, even in highly dense ion tracks. This method is suitable for the visualization of the penumbra region in a single-ion track with a high spatial resolution of 50 nm, which is sufficiently small to confirm that a single ion hits a cell nucleus with a size ranging between 5 and 20 μm.

  16. Heavy ion beam probing

    SciTech Connect

    Hickok, R L

    1980-07-01

    This report consists of the notes distributed to the participants at the IEEE Mini-Course on Modern Plasma Diagnostics that was held in Madison, Wisconsin in May 1980. It presents an overview of Heavy Ion Beam Probing that briefly describes the principles and discuss the types of measurements that can be made. The problems associated with implementing beam probes are noted, possible variations are described, estimated costs of present day systems, and the scaling requirements for large plasma devices are presented. The final chapter illustrates typical results that have been obtained on a variety of plasma devices. No detailed calculations are included in the report, but a list of references that will provide more detailed information is included.

  17. Heavy ion therapy: Bevalac epoch

    SciTech Connect

    Castro, J.R.

    1993-10-01

    An overview of heavy ion therapy at the Bevelac complex (SuperHILac linear accelerator + Bevatron) is given. Treatment planning, clinical results with helium ions on the skull base and uveal melanoma, clinical results with high-LET charged particles, neon radiotherapy of prostate cancer, heavy charged particle irradiation for unfavorable soft tissue sarcoma, preliminary results in heavy charged particle irradiation of bone sarcoma, and irradiation of bile duct carcinoma with charged particles and-or photons are all covered. (GHH)

  18. Insulated Conducting Cantilevered Nanotips and Two-Chamber Recording System for High Resolution Ion Sensing AFM

    PubMed Central

    Meckes, Brian; Arce, Fernando Teran; Connelly, Laura S.; Lal, Ratnesh

    2014-01-01

    Biological membranes contain ion channels, which are nanoscale pores allowing controlled ionic transport and mediating key biological functions underlying normal/abnormal living. Synthetic membranes with defined pores are being developed to control various processes, including filtration of pollutants, charge transport for energy storage, and separation of fluids and molecules. Although ionic transport (currents) can be measured with single channel resolution, imaging their structure and ionic currents simultaneously is difficult. Atomic force microscopy enables high resolution imaging of nanoscale structures and can be modified to measure ionic currents simultaneously. Moreover, the ionic currents can also be used to image structures. A simple method for fabricating conducting AFM cantilevers to image pore structures at high resolution is reported. Tungsten microwires with nanoscale tips are insulated except at the apex. This allows simultaneous imaging via cantilever deflections in normal AFM force feedback mode as well as measuring localized ionic currents. These novel probes measure ionic currents as small as picoampere while providing nanoscale spatial resolution surface topography and is suitable for measuring ionic currents and conductance of biological ion channels. PMID:24663394

  19. Lipid and Glycolipid Isomer Analyses Using Ultra-High Resolution Ion Mobility Spectrometry Separations.

    PubMed

    Wojcik, Roza; Webb, Ian K; Deng, Liulin; Garimella, Sandilya V B; Prost, Spencer A; Ibrahim, Yehia M; Baker, Erin S; Smith, Richard D

    2017-01-18

    Understanding the biological roles and mechanisms of lipids and glycolipids is challenging due to the vast number of possible isomers that may exist. Mass spectrometry (MS) measurements are currently the dominant approach for studying and providing detailed information on lipid and glycolipid presence and changes. However, difficulties in distinguishing the many structural isomers, due to the distinct lipid acyl chain positions, double bond locations or specific glycan types, inhibit the delineation and assignment of their biological roles. Here we utilized ultra-high resolution ion mobility spectrometry (IMS) separations by applying traveling waves in a serpentine multi-pass Structures for Lossless Ion Manipulations (SLIM) platform to enhance the separation of selected lipid and glycolipid isomers. The multi-pass arrangement allowed the investigation of paths ranging from ~16 m (one pass) to ~60 m (four passes) for the distinction of lipids and glycolipids with extremely small structural differences. These ultra-high resolution SLIM IMS-MS analyses provide a foundation for exploring and better understanding isomer-specific biological activities and disease processes.

  20. Lipid and Glycolipid Isomer Analyses Using Ultra-High Resolution Ion Mobility Spectrometry Separations

    PubMed Central

    Wojcik, Roza; Webb, Ian K.; Deng, Liulin; Garimella, Sandilya V. B.; Prost, Spencer A.; Ibrahim, Yehia M.; Baker, Erin S.; Smith, Richard D.

    2017-01-01

    Understanding the biological roles and mechanisms of lipids and glycolipids is challenging due to the vast number of possible isomers that may exist. Mass spectrometry (MS) measurements are currently the dominant approach for studying and providing detailed information on lipid and glycolipid presence and changes. However, difficulties in distinguishing the many structural isomers, due to the distinct lipid acyl chain positions, double bond locations or specific glycan types, inhibit the delineation and assignment of their biological roles. Here we utilized ultra-high resolution ion mobility spectrometry (IMS) separations by applying traveling waves in a serpentine multi-pass Structures for Lossless Ion Manipulations (SLIM) platform to enhance the separation of selected lipid and glycolipid isomers. The multi-pass arrangement allowed the investigation of paths ranging from ~16 m (one pass) to ~60 m (four passes) for the distinction of lipids and glycolipids with extremely small structural differences. These ultra-high resolution SLIM IMS-MS analyses provide a foundation for exploring and better understanding isomer-specific biological activities and disease processes. PMID:28106768

  1. Very high resolution soft x-ray spectrometer for an electron beam ion trap

    SciTech Connect

    Beiersdorfer, P.; Crespo Lopez-Urrutia, J.R.; Foerster, E.; Mahiri, J. |; Widmann, K.

    1997-01-01

    A very high resolution vacuum flat-crystal spectrometer was constructed for analyzing soft x rays emitted by an electron beam ion trap. The spectrometer was designed to operate at large Bragg angles ({theta}{le}85{degree}) in order to maximize the spectral dispersion and thus the resolving power. Using a quartz (100) crystal at a Bragg angle of 82{degree}, a measurement of the 2p{sub 1/2}, 2p{sub 3/2}{r_arrow}1s{sub 1/2} transitions in hydrogenic Mg{sup 11+} situated near 8.42 {Angstrom} was made. The nominal resolving power of the instrument was better than 30000 allowing us to infer the ion temperature (246{plus_minus}20 eV) from the observed line widths. A comparison with an existing flat-crystal spectrometer demonstrates the great improvement in resolving power achieved. {copyright} {ital 1997 American Institute of Physics.}

  2. Imaging using accelerated heavy ions

    SciTech Connect

    Chu, W.T.

    1982-05-01

    Several methods for imaging using accelerated heavy ion beams are being investigated at Lawrence Berkeley Laboratory. Using the HILAC (Heavy-Ion Linear Accelerator) as an injector, the Bevalac can accelerate fully stripped atomic nuclei from carbon (Z = 6) to krypton (Z = 34), and partly stripped ions up to uranium (Z = 92). Radiographic studies to date have been conducted with helium (from 184-inch cyclotron), carbon, oxygen, and neon beams. Useful ranges in tissue of 40 cm or more are available. To investigate the potential of heavy-ion projection radiography and computed tomography (CT), several methods and instrumentation have been studied.

  3. High Resolution Fluorescence Imaging of Cancers Using Lanthanide Ion-Doped Upconverting Nanocrystals

    PubMed Central

    Naccache, Rafik; Rodríguez, Emma Martín; Bogdan, Nicoleta; Sanz-Rodríguez, Francisco; de la Cruz, Maria del Carmen Iglesias; de la Fuente, Ángeles Juarranz; Vetrone, Fiorenzo; Jaque, Daniel; Solé, José García; Capobianco, John A.

    2012-01-01

    During the last decade inorganic luminescent nanoparticles that emit visible light under near infrared (NIR) excitation (in the biological window) have played a relevant role for high resolution imaging of cancer. Indeed, semiconductor quantum dots (QDs) and metal nanoparticles, mostly gold nanorods (GNRs), are already commercially available for this purpose. In this work we review the role which is being played by a relatively new class of nanoparticles, based on lanthanide ion doped nanocrystals, to target and image cancer cells using upconversion fluorescence microscopy. These nanoparticles are insulating nanocrystals that are usually doped with small percentages of two different rare earth (lanthanide) ions: The excited donor ions (usually Yb3+ ion) that absorb the NIR excitation and the acceptor ions (usually Er3+, Ho3+ or Tm3+), that are responsible for the emitted visible (or also near infrared) radiation. The higher conversion efficiency of these nanoparticles in respect to those based on QDs and GNRs, as well as the almost independent excitation/emission properties from the particle size, make them particularly promising for fluorescence imaging. The different approaches of these novel nanoparticles devoted to “in vitro” and “in vivo” cancer imaging, selective targeting and treatment are examined in this review. PMID:24213500

  4. Surface Structure and Lattice Dynamics of Alkali Halide Crystals Studied by High-Resolution Ion Scattering

    NASA Astrophysics Data System (ADS)

    Kido, Yoshiaki; Okazawa, Tetsuaki

    The rumpled surface structure and thermal lattice vibrations of KI(001) and RbI(001) were measured directly by high-resolution medium energy ion scattering (MEIS). The relaxation of interlayer distance between the top and second layer and the rumpling of the top and second layers were determined using the ion shadowing effect with an accuracy of 0.01 Å. From the displaced lattice positions determined above, we derived the dipole moments of the top- and second-layer ions self-consistently employing the polarizabilities estimated from the optical refractive index combined with the Clausius Mossotti relation. The balance between a short-range force and a long-range Coulombic one made it possible to judge the applicability of the short-range pair potentials proposed so far. We also determined the root-mean-square (rms) thermal vibration amplitudes of the bulk and the top-layer ions together with the correlations of the ions in the [001] and [101] strings by taking various kinds of scattering geometries. The results obtained were compared with those calculated from the molecular dynamics (MD) simulations based on a classical model using the dipole moments determined above and the Born Mayer type pair potential. The present MEIS results are in overall agreement with the MD simulations.

  5. High-resolution fast ion microscopy of single whole biological cells

    NASA Astrophysics Data System (ADS)

    Bettiol, Andrew A.; Mi, Zhaohong; Watt, Frank

    2016-12-01

    High-resolution microscopy techniques have become an essential tool in both biological and biomedical sciences, enabling the visualization of biological processes at cellular and subcellular levels. For many years, these imaging techniques utilized conventional optical microscopes including those with confocal facilities. However, the spatial resolutions achieved were largely limited to around 200 nm, as determined by the diffraction of light. To overcome this diffraction barrier, considerable scientific and technological effort has resulted in the development of super-resolution optical-based techniques, scanning probe microscopies, and also techniques utilizing charged particles (e.g., energetic electrons and ions) or high-energy photons (e.g., X-ray), which exhibit much shorter de Broglie wavelengths. Among the charged particle techniques, those utilizing mega-electron-volt (MeV) ion beams appear to have unique advantages primarily because MeV ions can penetrate through several microns of biological tissue (e.g., whole cells) with little deflection in their trajectories, and hence spatial resolutions are maintained while traversing the sample. Recently, we have witnessed the significant development of MeV ion beam focusing systems in reducing beam dimensions well below 100 nm, such that single whole cell imaging at 20 nm spatial resolutions is now possible. In this review, two super resolution imaging modalities that utilize MeV highly focused ion beams are discussed: Scanning Transmission Ion Microscopy (STIM), which images the areal density of cells and gives an insight into the cellular structure, and Proton/Helium-ion Induced Fluorescence Microcopy (P/HeIFM), which images the fluorescence emission of fluorescent markers and probes used as labels within the cells. This review hopes to demonstrate the potential of MeV ion microscopy, which is still in its infancy, and describe the simultaneous use of STIM and P/HeIFM as a new and powerful multifaceted

  6. Lipid and glycolipid isomer analyses using ultra-high resolution ion mobility spectrometry separations

    DOE PAGES

    Wojcik, Roza; Webb, Ian K.; Deng, Liulin; ...

    2017-01-18

    Understanding the biological mechanisms related to lipids and glycolipids is challenging due to the vast number of possible isomers. Mass spectrometry (MS) measurements are currently the dominant approach for studying and providing detailed information on lipid and glycolipid structures. However, difficulties in distinguishing many structural isomers (e.g. distinct acyl chain positions, double bond locations, as well as glycan isomers) inhibit the understanding of their biological roles. Here we utilized ultra-high resolution ion mobility spectrometry (IMS) separations based upon the use of traveling waves in a serpentine long path length multi-pass Structures for Lossless Manipulations (SLIM) to enhance isomer resolution. Themore » multi-pass arrangement allowed separations ranging from ~16 m (1 pass) to ~470 m (32 passes) to be investigated for the distinction of lipids and glycolipids with extremely small structural differences. Lastly, these ultra-high resolution SLIM IMS-MS analyses provide a foundation for exploring and better understanding isomer specific biological and disease processes.« less

  7. High-resolution vibrational and rotational spectroscopy of CD2H+ in a cryogenic ion trap

    NASA Astrophysics Data System (ADS)

    Jusko, Pavol; Stoffels, Alexander; Thorwirth, Sven; Brünken, Sandra; Schlemmer, Stephan; Asvany, Oskar

    2017-02-01

    The low-lying rotational states (J = 0, … , 5) of CD2H+ have been probed by high-resolution ro-vibrational and pure rotational spectroscopy, applying several action spectroscopic methods in a cryogenic 22-pole ion trap. For this, the ν1 ro-vibrational band has been revisited, detecting 108 transitions, among which 36 are new. The use of a frequency comb system allowed us to measure the ro-vibrational transitions with high precision and accuracy, typically better than 1 MHz. The high precision has been confirmed by comparing equal combination differences in the ground and excited state. Moreover, precise predictions of pure rotational transitions were possible for the ground state. Twenty-five rotational transitions have been detected directly by a novel IR-mm-wave double resonance method, giving rise to highly accurate ground state spectroscopic parameters.

  8. High resolution Laplace DLTS studies of defects in ion-implanted silicon

    NASA Astrophysics Data System (ADS)

    Evans-Freeman, J. H.; Abdelgader, N.; Kan, P. Y. Y.; Peaker, A. R.

    2002-01-01

    We have used high resolution Laplace deep level transient spectroscopy (LDLTS) to investigate defects in n-type silicon caused by implantation of Si, Ge or Er with doses of the order of 1×10 9 cm-2. These are compared with defects created in proton irradiated n-type silicon. Unlike the simple proton irradiated case, LDLTS spectra of ion implanted silicon show that there are many emission rates associated with defects with energies in the region of Ec-400 meV. We have carried out annealing studies and Laplace DLTS depth profiling and show that the complex spectra measured from a region less than half way through the implant simplify as the profile is moved through the implant and towards the tail. Annealing studies show that these defects survive an anneal that should remove the E-centre.

  9. Results of heavy ion radiotherapy

    SciTech Connect

    Castro, J.R.

    1994-04-01

    The potential of heavy ion therapy for clinical use in cancer therapy stems from the biological parameters of heavy charged particles, and their precise dose localization. Biologically, carbon, neon and other heavy ion beams (up to about silicon) are clinically useful in overcoming the radioresistance of hypoxic tumors, thus increasing biological effectiveness relative to low-LET x-ray or electron beams. Cells irradiated by heavy ions show less variation in cell-cycle related radiosensitivity and decreased repair of radiation injury. The physical parameters of these heavy charged particles allow precise delivery of high radiation doses to tumors while minimizing irradiation of normal tissues. Clinical use requires close interaction between radiation oncologists, medical physicists, accelerator physicists, engineers, computer scientists and radiation biologists.

  10. Chemical Imaging of Lipid Domains by High-Resolution Secondary Ion Mass Spectrometry

    SciTech Connect

    Kraft, M L; Weber, P K; Longo, M L; Hutcheon, I D; Boxer, S G

    2005-09-30

    Lipid microdomains within supported lipid bilayers composed of binary phosphocholine mixtures were chemically imaged by high-resolution secondary ion mass spectrometry performed with the NanoSIMS 50 (Cameca Instruments). This instrument images the sample components based on the elemental or isotopic composition of their atomic and small molecular secondary ions. Up to five different secondary ions can be simultaneously detected, and a lateral resolution of 50 nm can be achieved with high sensitivity at high mass resolution. In our experiments, the NanoSIMS 50 extensively fragmented the supported membrane, therefore an isotopic labeling strategy was used to encode the identities of the lipid components. Supported lipid membranes that contained distinct lipid microdomains were freeze-dried to preserve their lateral organization and analyzed with the NanoSIMS 50. Lipid microdomains as small as 100 nm in diameter were successfully imaged, and this was validated by comparison to AFM images taken at the same region prior to chemical imaging. Quantitative information on the lipid distribution within the domain was also determined by calibrating against supported membranes of known composition. We believe this will be a valuable approach for analyzing the composition of complex membrane domains with high spatial resolution.

  11. A compact high-resolution X-ray ion mobility spectrometer

    SciTech Connect

    Reinecke, T.; Kirk, A. T.; Heptner, A.; Niebuhr, D.; Böttger, S.; Zimmermann, S.

    2016-05-15

    For the ionization of gaseous samples, most ion mobility spectrometers employ radioactive ionization sources, e.g., containing {sup 63}Ni or {sup 3}H. Besides legal restrictions, radioactive materials have the disadvantage of a constant radiation with predetermined intensity. In this work, we replaced the {sup 3}H source of our previously described high-resolution ion mobility spectrometer with 75 mm drift tube length with a commercially available X-ray source. It is shown that the current configuration maintains the resolving power of R = 100 which was reported for the original setup containing a {sup 3}H source. The main advantage of an X-ray source is that the intensity of the radiation can be adjusted by varying its operating parameters, i.e., filament current and acceleration voltage. At the expense of reduced resolving power, the sensitivity of the setup can be increased by increasing the activity of the source. Therefore, the performance of the setup can be adjusted to the specific requirements of any application. To investigate the relation between operating parameters of the X-Ray source and the performance of the ion mobility spectrometer, parametric studies of filament current and acceleration voltage are performed and the influence on resolving power, peak height, and noise is analyzed.

  12. High Resolution Rutherford Back Scattering Estimation of the Surface Implanted Nitrogen Ion by Using Plasma-based Ion Implantation

    NASA Astrophysics Data System (ADS)

    Tanaka, Takeshi; Takagi, Toshinori

    Plasma-based ion implantation (PBII) with negative voltage pulses to the test specimen has been applied to the sterilization process as a technique suitable for three-dimensional work pieces. Pulsed high negative voltage (5 μs pulse width, 300 pulses/s, -800 V to -15 kV) was applied to the electrode in this process at a gas pressure of 2.4 Pa of N2. We found that the PBII process, in which (N2 gas self-ignitted plasma generated by only pulsed voltages is used) reduces the numbers of active Bacillus pumilus cell. The number of bacteria survivors was reduced by 10-5 x with 5 min exposure. As the ion energy is one of the important processing parameters on sterilization of the surface, the ion energy is discussed from the high resolution RBS depth profile.

  13. Separation of Peptide Isomers with Variant Modified Sites by High-Resolution Differential Ion Mobility Spectrometry

    SciTech Connect

    Shvartsburg, Alexandre A.; Creese, Andrew; Smith, Richard D.; Cooper, Helen J.

    2010-10-01

    Many proteins and proteolytic peptides incorporate the same post-translational modification (PTM) at different sites, creating multiple localization variants with different functions or activities that may coexist in cells. Current analytical methods based on liquid chromatography (LC) followed by tandem mass spectrometry (MS/MS) are challenged by such isomers that often co-elute in LC and/or produce non-unique fragments. Application of ion mobility spectrometry (IMS) has previously been explored, but success was limited by insufficient resolution. We show that the recently developed high-resolution differential ion mobility spectrometry (FAIMS) using helium-rich gases can readily separate phosphopeptides with variant modified sites. Specifically, use of He/N2 mixtures containing up to 74% He has allowed separating to >95% three monophosphorylated peptides of identical sequence. Similar separation was achieved at 50% He, using an elevated electric field. Bisphosphorylated isomers that differ in only one modification site were separated to the same extent. We anticipate the FAIMS capabilities for such separations to extend to other PTMs.

  14. Chemistry of heavy ion reactions

    SciTech Connect

    Hoffman, D.C.

    1988-10-01

    The use of heavy ions to induce nuclear reactions was reported as early as 1950. Since that time it has been one of the most active areas of nuclear research. Intense beams of ions as heavy as uranium with energies high enough to overcome the Coulomb barriers of even the heaviest elements are available. The wide variety of possible reactions gives rise to a multitude of products which have been studied by many ingenious chemical and physical techniques. Chemical techniques have been of special value for the separation and unequivocal identification of low yield species from the plethora of other nuclides present. Heavy ion reactions have been essential for the production of the trans-Md elements and a host of new isotopes. The systematics of compound nucleus reactions, transfer reactions, and deeply inelastic reactions have been elucidated using chemical techniques. A review of the variety of chemical procedures and techniques which have been developed for the study of heavy ion reactions and their products is given. Determination of the chemical properties of the trans-Md elements, which are very short-lived and can only be produced an ''atom-at-a-time'' via heavy ion reactions, is discussed. 53 refs., 19 figs.

  15. A test for Improvement of high resolution Quantitative Precipitation Estimation for localized heavy precipitation events

    NASA Astrophysics Data System (ADS)

    Lee, Jung-Hoon; Roh, Joon-Woo; Park, Jeong-Gyun

    2017-04-01

    Accurate estimation of precipitation is one of the most difficult and significant tasks in the area of weather diagnostic and forecasting. In the Korean Peninsula, heavy precipitations are caused by various physical mechanisms, which are affected by shortwave trough, quasi-stationary moisture convergence zone among varying air masses, and a direct/indirect effect of tropical cyclone. In addition to, various geographical and topographical elements make production of temporal and spatial distribution of precipitation is very complicated. Especially, localized heavy rainfall events in South Korea generally arise from mesoscale convective systems embedded in these synoptic scale disturbances. In weather radar data with high temporal and spatial resolution, accurate estimation of rain rate from radar reflectivity data is too difficult. Z-R relationship (Marshal and Palmer 1948) have adapted representatively. In addition to, several methods such as support vector machine (SVM), neural network, Fuzzy logic, Kriging were utilized in order to improve the accuracy of rain rate. These methods show the different quantitative precipitation estimation (QPE) and the performances of accuracy are different for heavy precipitation cases. In this study, in order to improve the accuracy of QPE for localized heavy precipitation, ensemble method for Z-R relationship and various techniques was tested. This QPE ensemble method was developed by a concept based on utilizing each advantage of precipitation calibration methods. The ensemble members were produced for a combination of different Z-R coefficient and calibration method.

  16. Swift Heavy Ions in Matter

    NASA Astrophysics Data System (ADS)

    Rothard, Hermann; Severin, Daniel; Trautmann, Christina

    2015-12-01

    The present volume contains the proceedings of the Ninth International Symposium on Swift Heavy Ions in Matter (SHIM). This conference was held in Darmstadt, from 18 to 21 May 2015. SHIM is a triennial series, which started about 25 years ago by a joint initiative of CIRIL - Caen and GSI - Darmstadt, with the aim of promoting fundamental and applied interdisciplinary research in the field of high-energy, heavy-ion interaction processes with matter. SHIM was successively organized in Caen (1989), Bensheim (1992), Caen (1995), Berlin (1998), Catania (2002), Aschaffenburg (2005), Lyon (2008), and Kyoto (2012). The conference attracts scientists from many different fields using high-energy heavy ions delivered by large accelerator facilities and characterized by strong and short electronic excitations.

  17. Heavy ion collisions and cosmology

    NASA Astrophysics Data System (ADS)

    Floerchinger, Stefan

    2016-12-01

    There are interesting parallels between the physics of heavy ion collisions and cosmology. Both systems are out-of-equilibrium and relativistic fluid dynamics plays an important role for their theoretical description. From a comparison one can draw interesting conclusions for both sides. For heavy ion physics it could be rewarding to attempt a theoretical description of fluid perturbations similar to cosmological perturbation theory. In the context of late time cosmology, it could be interesting to study dissipative properties such as shear and bulk viscosity and corresponding relaxation times in more detail. Knowledge and experience from heavy ion physics could help to constrain the microscopic properties of dark matter from observational knowledge of the cosmological fluid properties.

  18. High Resolution Visualization Applied to Future Heavy Airlift Concept Development and Evaluation

    NASA Technical Reports Server (NTRS)

    FordCook, A. B.; King, T.

    2012-01-01

    This paper explores the use of high resolution 3D visualization tools for exploring the feasibility and advantages of future military cargo airlift concepts and evaluating compatibility with existing and future payload requirements. Realistic 3D graphic representations of future airlifters are immersed in rich, supporting environments to demonstrate concepts of operations to key personnel for evaluation, feedback, and development of critical joint support. Accurate concept visualizations are reviewed by commanders, platform developers, loadmasters, soldiers, scientists, engineers, and key principal decision makers at various stages of development. The insight gained through the review of these physically and operationally realistic visualizations is essential to refining design concepts to meet competing requirements in a fiscally conservative defense finance environment. In addition, highly accurate 3D geometric models of existing and evolving large military vehicles are loaded into existing and proposed aircraft cargo bays. In this virtual aircraft test-loading environment, materiel developers, engineers, managers, and soldiers can realistically evaluate the compatibility of current and next-generation airlifters with proposed cargo.

  19. Accelerators for heavy ion fusion

    SciTech Connect

    Bangerter, R.O.

    1985-10-01

    Large fusion devices will almost certainly produce net energy. However, a successful commercial fusion energy system must also satisfy important engineering and economic constraints. Inertial confinement fusion power plants driven by multi-stage, heavy-ion accelerators appear capable of meeting these constraints. The reasons behind this promising outlook for heavy-ion fusion are given in this report. This report is based on the transcript of a talk presented at the Symposium on Lasers and Particle Beams for Fusion and Strategic Defense at the University of Rochester on April 17-19, 1985.

  20. Relativistic heavy ion facilities: worldwide

    SciTech Connect

    Schroeder, L.S.

    1986-05-01

    A review of relativistic heavy ion facilities which exist, are in a construction phase, or are on the drawing boards as proposals is presented. These facilities span the energy range from fixed target machines in the 1 to 2 GeV/nucleon regime, up to heavy ion colliders of 100 GeV/nucleon on 100 GeV/nucleon. In addition to specifying the general features of such machines, an outline of the central physics themes to be carried out at these facilities is given, along with a sampling of the detectors which will be used to extract the physics. 22 refs., 17 figs., 3 tabs.

  1. Ultra High-Resolution Electrospray Ionization/Ion Mobility Spectrometer System for In-Situ Detection of Organic Compounds

    NASA Technical Reports Server (NTRS)

    Kanik, I.; Beegle, L. W.; Hill, H. H.

    2001-01-01

    The potential of the high-resolution Electrospray Ionization/Ion Mobility Spectrometry (ESI/IMS) technique as analytical separation tool in analyzing bio-molecular mixtures in the search for the chemical signatures of life is demonstrated. Additional information is contained in the original extended abstract.

  2. Heavy ions in Jupiter's environment

    NASA Technical Reports Server (NTRS)

    Brown, R. A.

    1980-01-01

    The extended atmosphere of the Jupiter system consists of atoms and ions of heavy elements. This material originates on the satellite Io. Energy is lost from the thermal plasma in collisionally excited optical and ultraviolet emission. The juxtaposition of Earth and spacecraft measurements provide insight concerning the underlying processes of particle transport and energy supply.

  3. High resolution ion chamber array delivery quality assurance for robotic radiosurgery: Commissioning and validation.

    PubMed

    Blanck, Oliver; Masi, Laura; Chan, Mark K H; Adamczyk, Sebastian; Albrecht, Christian; Damme, Marie-Christin; Loutfi-Krauss, Britta; Alraun, Manfred; Fehr, Roman; Ramm, Ulla; Siebert, Frank-Andre; Stelljes, Tenzin Sonam; Poppinga, Daniela; Poppe, Björn

    2016-06-01

    High precision radiosurgery demands comprehensive delivery-quality-assurance techniques. The use of a liquid-filled ion-chamber-array for robotic-radiosurgery delivery-quality-assurance was investigated and validated using several test scenarios and routine patient plans. Preliminary evaluation consisted of beam profile validation and analysis of source-detector-distance and beam-incidence-angle response dependence. The delivery-quality-assurance analysis is performed in four steps: (1) Array-to-plan registration, (2) Evaluation with standard Gamma-Index criteria (local-dose-difference⩽2%, distance-to-agreement⩽2mm, pass-rate⩾90%), (3) Dose profile alignment and dose distribution shift until maximum pass-rate is found, and (4) Final evaluation with 1mm distance-to-agreement criterion. Test scenarios consisted of intended phantom misalignments, dose miscalibrations, and undelivered Monitor Units. Preliminary method validation was performed on 55 clinical plans in five institutions. The 1000SRS profile measurements showed sufficient agreement compared with a microDiamond detector for all collimator sizes. The relative response changes can be up to 2.2% per 10cm source-detector-distance change, but remains within 1% for the clinically relevant source-detector-distance range. Planned and measured dose under different beam-incidence-angles showed deviations below 1% for angles between 0° and 80°. Small-intended errors were detected by 1mm distance-to-agreement criterion while 2mm criteria failed to reveal some of these deviations. All analyzed delivery-quality-assurance clinical patient plans were within our tight tolerance criteria. We demonstrated that a high-resolution liquid-filled ion-chamber-array can be suitable for robotic radiosurgery delivery-quality-assurance and that small errors can be detected with tight distance-to-agreement criterion. Further improvement may come from beam specific correction for incidence angle and source

  4. Extended-range grazing-incidence spectrometer for high-resolution extreme ultraviolet measurements on an electron beam ion trapa)

    NASA Astrophysics Data System (ADS)

    Beiersdorfer, P.; Magee, E. W.; Brown, G. V.; Hell, N.; Träbert, E.; Widmann, K.

    2014-11-01

    A high-resolution grazing-incidence grating spectrometer has been implemented on the Livermore electron beam ion traps for performing very high-resolution measurements in the soft x-ray and extreme ultraviolet region spanning from below 10 Å to above 300 Å. The instrument operates without an entrance slit and focuses the light emitted by highly charged ions located in the roughly 50 μm wide electron beam onto a cryogenically cooled back-illuminated charge-coupled device detector. The measured line widths are below 0.025 Å above 100 Å, and the resolving power appears to be limited by the source size and Doppler broadening of the trapped ions. Comparisons with spectra obtained with existing grating spectrometers show an order of magnitude improvement in spectral resolution.

  5. Extended-range grazing-incidence spectrometer for high-resolution extreme ultraviolet measurements on an electron beam ion trap.

    PubMed

    Beiersdorfer, P; Magee, E W; Brown, G V; Hell, N; Träbert, E; Widmann, K

    2014-11-01

    A high-resolution grazing-incidence grating spectrometer has been implemented on the Livermore electron beam ion traps for performing very high-resolution measurements in the soft x-ray and extreme ultraviolet region spanning from below 10 Å to above 300 Å. The instrument operates without an entrance slit and focuses the light emitted by highly charged ions located in the roughly 50 μm wide electron beam onto a cryogenically cooled back-illuminated charge-coupled device detector. The measured line widths are below 0.025 Å above 100 Å, and the resolving power appears to be limited by the source size and Doppler broadening of the trapped ions. Comparisons with spectra obtained with existing grating spectrometers show an order of magnitude improvement in spectral resolution.

  6. Extended-range grazing-incidence spectrometer for high-resolution extreme ultraviolet measurements on an electron beam ion trap

    SciTech Connect

    Beiersdorfer, P.; Magee, E. W.; Brown, G. V.; Träbert, E.; Widmann, K.; Hell, N.

    2014-11-15

    A high-resolution grazing-incidence grating spectrometer has been implemented on the Livermore electron beam ion traps for performing very high-resolution measurements in the soft x-ray and extreme ultraviolet region spanning from below 10 Å to above 300 Å. The instrument operates without an entrance slit and focuses the light emitted by highly charged ions located in the roughly 50 μm wide electron beam onto a cryogenically cooled back-illuminated charge-coupled device detector. The measured line widths are below 0.025 Å above 100 Å, and the resolving power appears to be limited by the source size and Doppler broadening of the trapped ions. Comparisons with spectra obtained with existing grating spectrometers show an order of magnitude improvement in spectral resolution.

  7. Analyses of the temporal and spatial structures of heavy rainfall from a catalog of high-resolution radar rainfall fields

    NASA Astrophysics Data System (ADS)

    Thorndahl, Søren; Smith, James A.; Baeck, Mary Lynn; Krajewski, Witold F.

    2014-07-01

    In this paper, we develop a storm catalog of heavy rainfall events for a region centered on the Milwaukee, Wisconsin WSR-88D (Weather Surveillance Radar - 1988 Doppler) radar. The study region includes portions of southern Wisconsin, northern Illinois and Lake Michigan. The long-term objective of this study is to develop rainfall frequency analysis methods based on a storm catalog of major rain events. The specific objectives of this study are to develop a long-term catalog of high-resolution radar rainfall fields and characterize key features of the space-time variability of rainfall. The research questions that underlie these objectives are: 1) What are the spatial heterogeneities of rainfall over the study region for major flood-producing storm systems? 2) What are the key elements of storm evolution that control the scale-dependent properties of extreme rainfall? The storm catalog contains a record of the 50 “largest” storm days during the 1996-2011 observation period. We show that mean rainfall for the 50 largest storm days exhibits pronounced spatial heterogeneity with a broad maximum in western Wisconsin and a minimum in the eastern portion of the study region over Lake Michigan. We also show that there is a narrow line of maximum mean rainfall extending from west to east along the Wisconsin-Illinois border. This feature is tied to a maximum in the probability of daily rainfall exceeding 100 mm. There are characteristic elements to the storm life cycle of heavy rainfall days that relate to size, structure and evolution of heavy rainfall. Extreme rainfall is also linked with severe weather (tornados, large hail and damaging wind). The diurnal cycle of rainfall for heavy rain days is characterized by an early peak in the largest rainfall rates, an afternoon-evening peak in rain area exceeding 25 mm h- 1 and development of a large stratiform rain area during the night and early morning.

  8. Ion sources for heavy ion fusion (invited)

    NASA Astrophysics Data System (ADS)

    Yu, Simon S.; Eylon, S.; Chupp, W.; Henestroza, E.; Lidia, S.; Peters, C.; Reginato, L.; Tauschwitz, A.; Grote, D.; Deadrick, F.

    1996-03-01

    The development of ion sources for heavy ion fusion will be reported with particular emphasis on a recently built 2 MV injector. The new injector is based on an electrostatic quadrupole configuration, and has produced pulsed K+ ions of 950 mA peak from a 6.7 in. curved alumino silicate source. The ion beam has reached 2.3 MV with an energy flatness of ±0.2% over 1 μs. The measured normalized edge emittance of less than 1 π mm mrad is close to the source temperature limit. The design, construction, performance, and comparisons with three-dimensional particle-in-cell simulations will be described.

  9. Heavy Ion Heating from the Sun to 1AU

    NASA Astrophysics Data System (ADS)

    Korreck, K. E.; Lepri, S. T.; Kasper, J. C.; Case, A. W.; Kozarev, K. A.; Opher, M.; Evans, R. M.; Stevens, M. L.; Schwadron, N. A.

    2012-12-01

    The heating of heavy ions at the Sun and as they travel through the interplanetary space is relevant to both identifying the solar wind source region as well as the overall heating mechanisms and kinetics of the solar wind. Using ACE SWICS data on heavy ions from the shock associated with a CME on May 13, 2005, we examine the heavy ion heating and non-thermal nature of the helium distributions at 1AU as well as bulk solar wind parameters around the time of the CME. We utilize current work on high resolution 3D MHD models to compare the bulk solar wind parameters from the Sun to the inner heliosphere with a CME input. The relationship between the model's parameters and the observations at different regions of interest i.e the Solar Probe and Solar Orbiter orbits will be extrapolated. This model will in the future be extended to quiescent times of the solar wind.

  10. Heavy ion driver technology

    SciTech Connect

    Keefe, D.

    1988-09-01

    Major differences between fusion drivers and traditional accelerators include the following. The final beam current needed (/approximately/20 kA in a short pulse) is very much larger for a driver; such beams are dominated by repulsive space-charge effects since, even at 10 GeV, the ions are non-relativistic (v/c = 0.3). Also, the optical quality of the beams (called emittance by accelerator people) must be extremely good to ensure a suitably small focal spot at the pellet. Two schemes, one with a rf linac and storage rings, the other with a single-pass current-amplifying induction linac, are under study, the latter exclusively in the US. The induction linac approach lends itself to an examination in a sequence of scaled-down laboratory experiments since the most difficulties are expected to occur at the low energy end. Experiments and simulation have centered on a study of the transverse and longitudinal control of space-charge-dominated beams which are best described in terms of a non-neutral plasma rather than the traditional single-particle dynamics picture. An understanding of the high-current instability limits is required for arriving at a safe driver design. The final on-target beam current is so high that it must be carried in 16 separate focusing channels leading into the combustion chamber. While the energy deposition of the ions is expected to be entirely classical, there is a wealth of plasma physics phenomena to be explored (by theory and simulation) in the final propagation of these beams through the low-density gas in the chamber and in the environment of the hot target; it is important that none of these could result in a significant portion of the beam missing the focal spot. 13 refs., 9 figs., 1 tab.

  11. High-Resolution 3D Imaging and Quantification of Gold Nanoparticles in a Whole Cell Using Scanning Transmission Ion Microscopy

    PubMed Central

    Chen, Xiao; Chen, Ce-Belle; Udalagama, Chammika N.B.; Ren, Minqin; Fong, Kah Ee; Yung, Lin Yue Lanry; Giorgia, Pastorin; Bettiol, Andrew Anthony; Watt, Frank

    2013-01-01

    Increasing interest in the use of nanoparticles (NPs) to elucidate the function of nanometer-sized assemblies of macromolecules and organelles within cells, and to develop biomedical applications such as drug delivery, labeling, diagnostic sensing, and heat treatment of cancer cells has prompted investigations into novel techniques that can image NPs within whole cells and tissue at high resolution. Using fast ions focused to nanodimensions, we show that gold NPs (AuNPs) inside whole cells can be imaged at high resolution, and the precise location of the particles and the number of particles can be quantified. High-resolution density information of the cell can be generated using scanning transmission ion microscopy, enhanced contrast for AuNPs can be achieved using forward scattering transmission ion microscopy, and depth information can be generated from elastically backscattered ions (Rutherford backscattering spectrometry). These techniques and associated instrumentation are at an early stage of technical development, but we believe there are no physical constraints that will prevent whole-cell three-dimensional imaging at <10 nm resolution. PMID:23561518

  12. LDEF (Postflight), AO178 : A High-Resolution Study of Ultra-heavy Cosmic-Ray Nuclei, Tray D05

    NASA Technical Reports Server (NTRS)

    1990-01-01

    LDEF (Postflight), AO178 : A High-Resolution Study of Ultra-heavy Cosmic-Ray Nuclei, Tray D05 EL-1994-00311 LDEF (Postflight), AO178 : A High-Resolution Study of Ultra-heavy Cosmic-Ray Nuclei, Tray D05 The postflight photograph of the Ultra Heavy Cosmic Ray Experiment (UHCRE) was taken in SAEF II at KSC after removal of the experiment tray from the LDEF. The experiment tray flanges appear discolored by a brown stain. Outlines of experiment tray clamp blocks are clearly visible on the upper and lower tray flanges. The experiment tray holding fixture hardware covers the clamp block areas on the end flanges. The UHCRE detectors were contained in 16 peripheral LDEF trays with at least one UHCRE tray located on each row of the LDEF except row 3, row 9 and row 12. Each tray contains three cylindrical aluminum pressure vessels with an integral aluminum support structure. Each cylinder is filled with an Eccofoam insert that houses 4 UHCRE detector stacks. Each stack consist of layers of Lexan polycarbonate sheets (approximately 70) interleaved with several thin sheets of lead. Forty-seven of the 48 pressure vessels were pressurized to 1.0 bar of a dry gas mixture (oxygen, nitrogen and helium) and sealed. One of the units was left unsealed in order to investigate the effects of the vacuum environment on the detector materials. Thermal control was accomplished by attaching an aluminized Kapton thermal cover on the tray bottom (the Kapton facing the LDEF interior), placing the aluminum cylinder support structure on thermal isolators and covering the experiment with a thin (5 mil) silvered TEFLON® thermal cover. The silvered TEFLON® cover was supported by an aluminum frame, an integral part of the experiment structure, and held in place by Velcro pads selectively located on the frame and on the back of the cover. The copper colored strip extending over the trays lower flange is a copper coated pressure sensitive tape used to provide an electrical ground between the

  13. The Relativistic Heavy Ion Collider, Rhic

    NASA Astrophysics Data System (ADS)

    Foelsche, H.; Hahn, H.; Harrison, M.; Ozaki, S.; Rhoades-Brown, M. J.

    1993-03-01

    The scope of the first relativistic energy heavy ion collider, RHIC, is discussed. Particular attention is paid to those novel features of a heavy ion collider that are distinct from the more usual proton machines. These features are derived from the experimental requirements of operation with a variety of ion species over a wide energy range as well as the increased demands on available ion sources and injector complexes. Storage of heavy ion beams for many hours is severely impacted by intrabeam scattering.

  14. Semiholography for heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Mukhopadhyay, Ayan; Preis, Florian

    2017-03-01

    The formation of QGP in heavy ion collisions gives us a great opportunity for learning about nonperturbative dynamics of QCD. Semiholography provides a new consistent framework to combine perturbative and non-perturbative effects in a coherent way and can be applied to obtain an effective description for heavy ion collisions. In particular, it allows us to include nonperturbative effects in existing glasma effective theory and QCD kinetic theory for the weakly coupled saturated degrees of freedom liberated by the collisions in the initial stages in a consistent manner. We argue why the full framework should be able to confront experiments with only a few phenomenological parameters and present feasibility tests for the necessary numerical computations. Furthermore, we discuss that semiholography leads to a new description of collective flow in the form of a generalised non-Newtonian fluid. We discuss some open questions which we hope to answer in the near future.

  15. Virtually distortion-free imaging system for large field, high resolution lithography using electrons, ions or other particle beams

    DOEpatents

    Hawryluk, A.M.; Ceglio, N.M.

    1993-01-12

    Virtually distortion free large field high resolution imaging is performed using an imaging system which contains large field distortion or field curvature. A reticle is imaged in one direction through the optical system to form an encoded mask. The encoded mask is then imaged back through the imaging system onto a wafer positioned at the reticle position. Particle beams, including electrons, ions and neutral particles, may be used as well as electromagnetic radiation.

  16. Virtually distortion-free imaging system for large field, high resolution lithography using electrons, ions or other particle beams

    DOEpatents

    Hawryluk, Andrew M.; Ceglio, Natale M.

    1993-01-01

    Virtually distortion free large field high resolution imaging is performed using an imaging system which contains large field distortion or field curvature. A reticle is imaged in one direction through the optical system to form an encoded mask. The encoded mask is then imaged back through the imaging system onto a wafer positioned at the reticle position. Particle beams, including electrons, ions and neutral particles, may be used as well as electromagnetic radiation.

  17. STAR heavy-ion highlights

    NASA Astrophysics Data System (ADS)

    Rusnakova, Olga

    2016-11-01

    Parton energy loss, quarkonium sequential melting and particle production from electromagnetic interactions are tools to study Quark Gluon Plasma properties. The STAR detector, with large acceptance at mid-rapidity, excellent particle identification and wide transverse momentum coverage, is able to study these probes in details. Di-electron spectra form Beam Energy Scan, measurements of reconstructed jets in Au+Au collisions and quarkonium measurements in p+p and heavy ion collisions are reported in this paper.

  18. Central collisions of heavy ions

    SciTech Connect

    Fung, Sun-yiu.

    1992-10-01

    This report describes the activities of the Heavy Ion Physics Group at the University of California, Riverside from October 1, 1991 to September 30, 1992. During this period, the program focused on particle production at AGS energies, and correlation studies at the Bevalac in nucleus-nucleus central collisions. As part of the PHENIX collaboration, contributions were made to the Preliminary Conceptual Design Report (pCDR), and work on a RHIC silicon microstrip detector R D project was performed.

  19. Heavy ion measurement on LDEF

    NASA Technical Reports Server (NTRS)

    Jonathal, D.; Beaujean, R.; Enge, W.

    1993-01-01

    Heavy ions with nuclear charge Z = 6 to Z = 26 are detected in a stack of plastic track detectors. The measured energies in the range of 10-240 MeV/nuc are well below the geomagnetic cut off value of the Long Duration Exposure Facility (LDEF) orbit. The arrival directions of the low energy particles (Z = 6-26, E less than 40 MeV/nuc) are consistent with a trapped component incident in the South Atlantic Anomaly.

  20. Analysis of bromotryptophan and hydroxyproline modifications by high-resolution, high-accuracy precursor ion scanning utilizing fragment ions with mass-deficient mass tags.

    PubMed

    Steen, Hanno; Mann, Matthias

    2002-12-15

    Protein modifications are often detected by precursor ion scanning. When quadrupole TOF mass spectrometers are used for precursor ion scanning with high-resolution, high-accuracy fragment ion selection, "reporter" ions are required to have a unique mass within +/-0.04 Da or less instead of +/-0.5 Da on triple quadrupole mass spectrometers, the traditional instrument used for precursor ion scanning. Thus, characteristic fragment ions can be utilized even if other fragment ions have the same nominal mass as long as the characteristic fragment ions are slightly mass deficient as compared to the other fragments, i.e., when they have an inherent mass-deficient mass tag. Here, the immonium ions of bromotryptophan and hydroxyproline are described as two fragment ions characteristic for tryptophan-brominated and proline-hydroxylated peptides, respectively. The "reporter" ion of trytophan-brominated peptides is highly mass deficient due to the presence of bromine, thereby allowing the selective detection of these species and the distinction from other dipeptidic a-, b-, and y-fragment ions by high-resolution, high-accuracy precursor ion scanning. This strategy also enables the differentiation between precursors giving rise to the oxygen-containing immonium ion of hydroxyproline and precursors of the immonium ions of near-ubiquitous leucine/isoleucine. Both immonium ions have the same nominal mass of 86 Da, but the exact masses differ by less than 0.04 Da. High-resolution, high-accuracy precursor ion scanning enabled the identification of proline-hydroxylated and tryptophan-brominated species and the directed analysis of species carrying these modifications in a highly complex Conus textile conotoxin mixture. This lead to the characterization of one novel C. textile conotoxin containing a bromotryptophan residue and one novel C. textile conotoxin carrying two hydroxyproline residues.

  1. The ANSTO high energy heavy ion microprobe

    NASA Astrophysics Data System (ADS)

    Siegele, Rainer; Cohen, David D.; Dytlewski, Nick

    1999-10-01

    Recently the construction of the ANSTO High Energy Heavy Ion Microprobe (HIMP) at the 10 MV ANTARES tandem accelerator has been completed. The high energy heavy ion microprobe focuses not only light ions at energies of 2-3 MeV, but is also capable of focusing heavy ions at high energies with ME/ q2 values up to 150 MeV amu and greater. First performance tests and results are reported here.

  2. High-resolution simulations of heavy precipitation events: role of the Adriatic SST and air-sea interactions

    NASA Astrophysics Data System (ADS)

    Davolio, Silvio; Stocchi, Paolo

    2016-04-01

    Strong Bora and Sirocco winds over the Adriatic Sea favour intense air-sea interactions and are often associated with heavy rainfall that affects the mountainous areas surrounding the basin. A convection-permitting model (MOLOCH) has been implemented at high resolution (2 km) in order to analyse several precipitation events over northern Italy, occurred during different seasons of the year and presenting different rainfall characteristics (stratiform, convective, orographic), and to possibly identify the relevant physical mechanisms involved. With the aim of assessing the impact of the sea surface temperature (SST) and surface fluxes on the intensity and location of the rainfall, sensitivity experiments have been performed taking into account the possible variability of SST analysis for model initialization. The model has been validated and specific diagnostic tools have been developed and applied to evaluate the vertically integrated moisture fluxes feeding the precipitating system or to compute a water balance in the atmosphere over the sea. The results show that the Adriatic Sea plays a role in determining the boundary layer characteristics through exchange of heat and moisture thus modifying the low-level flow dynamics and its interaction with the orography. This in turn impacts on the rainfall. Although the results vary among the analysed events, the precise definition of the SST and its evolution can be relevant for accurate precipitation forecasting.

  3. Higher sensitivity secondary ion mass spectrometry of biological molecules for high resolution, chemically specific imaging.

    PubMed

    McDonnell, Liam A; Heeren, Ron M A; de Lange, Robert P J; Fletcher, Ian W

    2006-09-01

    To expand the role of high spatial resolution secondary ion mass spectrometry (SIMS) in biological studies, numerous developments have been reported in recent years for enhancing the molecular ion yield of high mass molecules. These include both surface modification, including matrix-enhanced SIMS and metal-assisted SIMS, and polyatomic primary ions. Using rat brain tissue sections and a bismuth primary ion gun able to produce atomic and polyatomic primary ions, we report here how the sensitivity enhancements provided by these developments are additive. Combined surface modification and polyatomic primary ions provided approximately 15.8 times more signal than using atomic primary ions on the raw sample, whereas surface modification and polyatomic primary ions yield approximately 3.8 and approximately 8.4 times more signal. This higher sensitivity is used to generate chemically specific images of higher mass biomolecules using a single molecular ion peak.

  4. Rapid prototyping of Fresnel zone plates via direct Ga(+) ion beam lithography for high-resolution X-ray imaging.

    PubMed

    Keskinbora, Kahraman; Grévent, Corinne; Eigenthaler, Ulrike; Weigand, Markus; Schütz, Gisela

    2013-11-26

    A significant challenge to the wide utilization of X-ray microscopy lies in the difficulty in fabricating adequate high-resolution optics. To date, electron beam lithography has been the dominant technique for the fabrication of diffractive focusing optics called Fresnel zone plates (FZP), even though this preparation method is usually very complicated and is composed of many fabrication steps. In this work, we demonstrate an alternative method that allows the direct, simple, and fast fabrication of FZPs using focused Ga(+) beam lithography practically, in a single step. This method enabled us to prepare a high-resolution FZP in less than 13 min. The performance of the FZP was evaluated in a scanning transmission soft X-ray microscope where nanostructures as small as sub-29 nm in width were clearly resolved, with an ultimate cutoff resolution of 24.25 nm, demonstrating the highest first-order resolution for any FZP fabricated by the ion beam lithography technique. This rapid and simple fabrication scheme illustrates the capabilities and the potential of direct ion beam lithography (IBL) and is expected to increase the accessibility of high-resolution optics to a wider community of researchers working on soft X-ray and extreme ultraviolet microscopy using synchrotron radiation and advanced laboratory sources.

  5. Deciphering metal ion preference and primary coordination sphere robustness of a designed zinc finger with high-resolution mass spectrometry.

    PubMed

    Laitaoja, Mikko; Isoniemi, Sari; Valjakka, Jarkko; Mándity, István M; Jänis, Janne

    2017-02-01

    Small zinc finger (ZnF) motifs are promising molecular scaffolds for protein design owing to their structural robustness and versatility. Moreover, their characterization provides important insights into protein folding in general. ZnF motifs usually possess an exceptional specificity and high affinity towards Zn(II) ion to drive folding. While the Zn(II) ion is canonically coordinated by two cysteine and two histidine residues, many other coordination spheres also exist in small ZnFs, all having four amino acid ligands. Here we used high-resolution mass spectrometry to study metal ion binding specificity and primary coordination sphere robustness of a designed zinc finger, named MM1. Based on the results, MM1 possesses high specificity for zinc with sub-micromolar binding affinity. Surprisingly, MM1 retains metal ion binding affinity even in the presence of selective alanine mutations of the primary zinc coordinating amino acid residues. © 2016 The Protein Society.

  6. High Resolution Infrared Spectroscopy of Slit-Jet Cooled Radicals and Ions

    NASA Astrophysics Data System (ADS)

    Roberts, Melanie A.

    This thesis presents high-resolution spectra of supersonically-cooled organic radicals in the mid-infrared, the details and design of the instruments necessary to obtain the spectra, and the theory to understand the spectra and the larger context of the results. Specifically, four organic radicals are studied: singly-deuterated methyl radical (CH2D), phenyl radical (C6H5), hydroxymethyl radical (CH2OH), and ethynyl radical (C2H). All of the spectroscopic studies presented use an existing mid-infrared high-resolution spectrometer with a frequency precision of better than 10 MHz. The radicals are generated using a discharge to dissociate a neutral precursor and form the radicals. The discharge is localized at the orifice of a slit supersonic expansion, which cools the radicals to around 20 K and allows for sub-Doppler spectral resolution. In addition to the description of the existing spectrometer, the design, construction, and successful testing of a new, automated mid-infrared spectrometer is presented. The new spectrometer is based upon difference frequency generation of a scanning Ti:Sapphire laser and a single-frequency Nd:YAG laser to create high-resolution mid-infrared radiation. The new system speeds up data-taking by fully automating the scanning process. The four radicals studied in this thesis are all intermediates in combustion processes of hydrocarbon fuels. First, the out-of-phase symmetric stretch of phenyl radical is presented. As the first high-resolution infrared study of phenyl, it paves the way for future studies of this and other aromatic radicals. Second, the two fundamental CH stretches in CH2D are studied with full rotational resolution. The narrow linewidth of the transitions reveals resolved fine structure and partially resolved hyperfine structure. This resolution yields additional information regarding the distribution of electrons in the radical. With this study of CH2D, a nearly complete set of vibrational frequencies is present in the

  7. LDEF (Postflight), AO178 : A High-Resolution Study of Ultra-heavy Cosmic-Ray Nuclei, Tray C11

    NASA Technical Reports Server (NTRS)

    1990-01-01

    LDEF (Postflight), AO178 : A High-Resolution Study of Ultra-heavy Cosmic-Ray Nuclei, Tray C11 EL-1994-00299 LDEF (Postflight), AO178 : A High-Resolution Study of Ultra-heavy Cosmic-Ray Nuclei, Tray C11 The postflight photograph of the Ultra Heavy Cosmic Ray Experiment (UHCRE) was taken in SAEF II at KSC after removal of the experiment tray from the LDEF. The experiment tray flanges appear discolored by a light brown stain. Outlines of experiment tray clamp blocks are faint but visible on the upper and lower experiment tray flanges.The experiment tray holding fixture hardware covers the clamp block areas on the end flanges. The UHCRE detectors were contained in 16 peripheral LDEF trays with at least one UHCRE tray located on each row of the LDEF except row 3, row 9 and row 12. Each tray contains three cylindrical aluminum pressure vessels with an integral aluminum support structure. Each cylinder is filled with an Eccofoam insert that houses 4 UHCRE detector stacks. Each stack consist of layers of Lexan polycarbonate sheets (approximately 70) interleaved with several thin sheets of lead. Forty-seven of the 48 pressure vessels were pressurized to 1.0 bar of a dry gas mixture (oxygen, nitrogen and helium) and sealed. One of the units was left unsealed in order to investigate the effects of the vacuum environment on the detector materials. Thermal control was accomplished by attaching an aluminized Kapton thermal cover on the tray bottom (the Kapton facing the LDEF interior), placing the aluminum cylinder support structure on thermal isolators and covering the experiment with a thin (5 mil) silvered TEFLON® thermal cover. The silvered TEFLON® cover was supported by an aluminum frame, an integral part of the experiment structure, and held in place by Velcro pads selectively located on the frame and on the back of the cover. The copper colored strip extending over the trays lower flange is a copper coated pressure sensitive tape used to provide an electrical ground

  8. Role of land state in a high resolution mesoscale model for simulating the Uttarakhand heavy rainfall event over India

    NASA Astrophysics Data System (ADS)

    Rajesh, P. V.; Pattnaik, S.; Rai, D.; Osuri, K. K.; Mohanty, U. C.; Tripathy, S.

    2016-04-01

    In 2013, Indian summer monsoon witnessed a very heavy rainfall event (>30 cm/day) over Uttarakhand in north India, claiming more than 5000 lives and property damage worth approximately 40 billion USD. This event was associated with the interaction of two synoptic systems, i.e., intensified subtropical westerly trough over north India and north-westward moving monsoon depression formed over the Bay of Bengal. The event had occurred over highly variable terrain and land surface characteristics. Although global models predicted the large scale event, they failed to predict realistic location, timing, amount, intensity and distribution of rainfall over the region. The goal of this study is to assess the impact of land state conditions in simulating this severe event using a high resolution mesoscale model. The land conditions such as multi-layer soil moisture and soil temperature fields were generated from High Resolution Land Data Assimilation (HRLDAS) modelling system. Two experiments were conducted namely, (1) CNTL (Control, without land data assimilation) and (2) LDAS, with land data assimilation (i.e., with HRLDAS-based soil moisture and temperature fields) using Weather Research and Forecasting (WRF) modelling system. Initial soil moisture correlation and root mean square error for LDAS is 0.73 and 0.05, whereas for CNTL it is 0.63 and 0.053 respectively, with a stronger heat low in LDAS. The differences in wind and moisture transport in LDAS favoured increased moisture transport from Arabian Sea through a convectively unstable region embedded within two low pressure centers over Arabian Sea and Bay of Bengal. The improvement in rainfall is significantly correlated to the persistent generation of potential vorticity (PV) in LDAS. Further, PV tendency analysis confirmed that the increased generation of PV is due to the enhanced horizontal PV advection component rather than the diabatic heating terms due to modified flow fields. These results suggest that, two

  9. High resolution Thomson Parabola Spectrometer for full spectral capture of multi-species ion beams

    NASA Astrophysics Data System (ADS)

    Alejo, A.; Kar, S.; Tebartz, A.; Ahmed, H.; Astbury, S.; Carroll, D. C.; Ding, J.; Doria, D.; Higginson, A.; McKenna, P.; Neumann, N.; Scott, G. G.; Wagner, F.; Roth, M.; Borghesi, M.

    2016-08-01

    We report on the experimental characterisation of laser-driven ion beams using a Thomson Parabola Spectrometer (TPS) equipped with trapezoidally shaped electric plates, proposed by Gwynne et al. [Rev. Sci. Instrum. 85, 033304 (2014)]. While a pair of extended (30 cm long) electric plates was able to produce a significant increase in the separation between neighbouring ion species at high energies, deploying a trapezoidal design circumvented the spectral clipping at the low energy end of the ion spectra. The shape of the electric plate was chosen carefully considering, for the given spectrometer configuration, the range of detectable ion energies and species. Analytical tracing of the ion parabolas matches closely with the experimental data, which suggests a minimal effect of fringe fields on the escaping ions close to the wedged edge of the electrode. The analytical formulae were derived considering the relativistic correction required for the high energy ions to be characterised using such spectrometer.

  10. High resolution Thomson Parabola Spectrometer for full spectral capture of multi-species ion beams.

    PubMed

    Alejo, A; Kar, S; Tebartz, A; Ahmed, H; Astbury, S; Carroll, D C; Ding, J; Doria, D; Higginson, A; McKenna, P; Neumann, N; Scott, G G; Wagner, F; Roth, M; Borghesi, M

    2016-08-01

    We report on the experimental characterisation of laser-driven ion beams using a Thomson Parabola Spectrometer (TPS) equipped with trapezoidally shaped electric plates, proposed by Gwynne et al. [Rev. Sci. Instrum. 85, 033304 (2014)]. While a pair of extended (30 cm long) electric plates was able to produce a significant increase in the separation between neighbouring ion species at high energies, deploying a trapezoidal design circumvented the spectral clipping at the low energy end of the ion spectra. The shape of the electric plate was chosen carefully considering, for the given spectrometer configuration, the range of detectable ion energies and species. Analytical tracing of the ion parabolas matches closely with the experimental data, which suggests a minimal effect of fringe fields on the escaping ions close to the wedged edge of the electrode. The analytical formulae were derived considering the relativistic correction required for the high energy ions to be characterised using such spectrometer.

  11. High resolution Thomson Parabola Spectrometer for full spectral capture of multi-species ion beams

    SciTech Connect

    Alejo, A.; Kar, S. Ahmed, H.; Doria, D.; Borghesi, M.; Tebartz, A.; Ding, J.; Neumann, N.; Astbury, S.; Carroll, D. C.; Scott, G. G.; Higginson, A.; McKenna, P.; Wagner, F.; Roth, M.

    2016-08-15

    We report on the experimental characterisation of laser-driven ion beams using a Thomson Parabola Spectrometer (TPS) equipped with trapezoidally shaped electric plates, proposed by Gwynne et al. [Rev. Sci. Instrum. 85, 033304 (2014)]. While a pair of extended (30 cm long) electric plates was able to produce a significant increase in the separation between neighbouring ion species at high energies, deploying a trapezoidal design circumvented the spectral clipping at the low energy end of the ion spectra. The shape of the electric plate was chosen carefully considering, for the given spectrometer configuration, the range of detectable ion energies and species. Analytical tracing of the ion parabolas matches closely with the experimental data, which suggests a minimal effect of fringe fields on the escaping ions close to the wedged edge of the electrode. The analytical formulae were derived considering the relativistic correction required for the high energy ions to be characterised using such spectrometer.

  12. Vibronic fine structure in high-resolution x-ray absorption spectra from ion-bombarded boron nitride nanotubes

    SciTech Connect

    Petravic, Mladen; Peter, Robert; Varasanec, Marijana; Li Luhua; Chen Ying; Cowie, Bruce C. C.

    2013-05-15

    The authors have applied high-resolution near-edge x-ray absorption fine structure measurements around the nitrogen K-edge to study the effects of ion-bombardment on near-surface properties of boron nitride nanotubes. A notable difference has been observed between surface sensitive partial electron yield (PEY) and bulk sensitive total electron yield (TEY) fine-structure measurements. The authors assign the PEY fine structure to the coupling of excited molecular vibrational modes to electronic transitions in NO molecules trapped just below the surface. Oxidation resistance of the boron nitride nanotubes is significantly reduced by low energy ion bombardment, as broken B-N bonds are replaced by N-O bonds involving oxygen present in the surface region. In contrast to the PEY spectra, the bulk sensitive TEY measurements on as-grown samples do not exhibit any fine structure while the ion-bombarded samples show a clear vibronic signature of molecular nitrogen.

  13. High resolution ion mobility measurements for gas phase proteins: correlation between solution phase and gas phase conformations

    NASA Astrophysics Data System (ADS)

    Hudgins, Robert R.; Woenckhaus, Jürgen; Jarrold, Martin F.

    1997-11-01

    Our high resolution ion mobility apparatus has been modified by attaching an electrospray source to perform measurements for biological molecules. While the greater resolving power permits the resolution of more conformations for BPTI and cytochrome c, the resolved features are generally much broader than expected for a single rigid conformation. A major advantage of the new experimental configuration is the much gentler introduction of ions into the drift tube, so that the observed gas phase conformations appear to more closely reflect those present in solution. For example, it is possible to distinguish between the native state of cytochrome c and the methanol-denatured form on the basis of the ion mobility measurements; the mass spectra alone are not sensitive enough to detect this change. Thus this approach may provide a quick and sensitive tool for probing the solution phase conformations of biological molecules.

  14. High-Resolution Measurements of Photoionization of Ions Using Synchrotron Radiation

    SciTech Connect

    Aguilar, A.; Covington, A.M.; Emmons, E.D.; Gharaibeh, M.F.; Phaneuf, R.A.; Alvarez, I.; Cisneros, C.; Hinojosa, G.; Dominguez, I.; Ackerman, G.; Bozek, J.D.; Canton, S.; Rude, B.; Sant'Anna, M.M.; Schlachter, A. S.; Folkmann, F.

    2003-08-26

    Measurement of absolute cross sections for photoionization of ions has become feasible by merging a well-collimated ion beam with a monochromatic beam of synchrotron radiation. An electron cyclotron resonance (ECR) ion source permits such measurements to be extended to multiply charged ions, and makes possible systematic studies along isoelectronic sequences. The evolution of atomic spectra along such sequences is commonly studied theoretically, but the predictive ability of the theoretical methods remains largely untested. Absolute cross-section measurements are presented for the first three ionic members of the isoelectronic sequence of nitrogen (O+, F2+ and Ne3+)

  15. The Bucharest heavy ion accelerator facility

    NASA Astrophysics Data System (ADS)

    Ceauşescu, V.; Dobrescu, S.; Duma, M.; Indreas, G.; Ivaşcu, M.; Păpureanu, S.; Pascovici, G.; Semenescu, G.

    1986-02-01

    The heavy ion accelerator facility of the Heavy Ion Physics Department at the Institute of Physics and Nuclear Engineering in Bucharest is described. The Tandem accelerator development and the operation of the first stage of the heavy ion postaccelerating system are discussed. Details are given concerning the resonance cavities, the pulsing system matching the dc beam to the RF cavities and the computer control system.

  16. Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg2+ channel MgtE.

    PubMed

    Takeda, Hironori; Hattori, Motoyuki; Nishizawa, Tomohiro; Yamashita, Keitaro; Shah, Syed T A; Caffrey, Martin; Maturana, Andrés D; Ishitani, Ryuichiro; Nureki, Osamu

    2014-11-04

    Magnesium is the most abundant divalent cation in living cells and is crucial to several biological processes. MgtE is a Mg(2+) channel distributed in all domains of life that contributes to the maintenance of cellular Mg(2+) homeostasis. Here we report the high-resolution crystal structures of the transmembrane domain of MgtE, bound to Mg(2+), Mn(2+) and Ca(2+). The high-resolution Mg(2+)-bound crystal structure clearly visualized the hydrated Mg(2+) ion within its selectivity filter. Based on those structures and biochemical analyses, we propose a cation selectivity mechanism for MgtE in which the geometry of the hydration shell of the fully hydrated Mg(2+) ion is recognized by the side-chain carboxylate groups in the selectivity filter. This is in contrast to the K(+)-selective filter of KcsA, which recognizes a dehydrated K(+) ion. Our results further revealed a cation-binding site on the periplasmic side, which regulate channel opening and prevents conduction of near-cognate cations.

  17. The Relativistic Heavy Ion Collider

    NASA Astrophysics Data System (ADS)

    Fischer, Wolfram

    The Relativistic Heavy Ion Collider (RHIC), shown in Fig. 1, was build to study the interactions of quarks and gluons at high energies [Harrison, Ludlam and Ozaki (2003)]. The theory of Quantum Chromodynamics (QCD) describes these interactions. One of the main goals for the RHIC experiments was the creation and study of the Quark-Gluon Plasma (QGP), which was expected to be formed after the collision of heavy ions at a temperature of approximately 2 trillion kelvin (or equivalently an energy of 150 MeV). The QGP is the substance which existed only a few microseconds after the Big Bang. The QGP was anticipated to be weakly interacting like a gas but turned out to be strongly interacting and more like a liquid. Among its unusual properties is its extremely low viscosity [Auerbach and Schlomo (2009)], which makes the QGP the substance closest to a perfect liquid known to date. The QGP is opaque to moderate energy quarks and gluons leading to a phenomenon called jet quenching, where of a jet and its recoil jet only one is observable and the other suppressed after traversing and interacting with the QGP [Jacak and Müller (2012)]...

  18. Heavy ion measurement on LDEF

    NASA Technical Reports Server (NTRS)

    Beaujean, R.; Jonathal, D.; Enge, W.

    1991-01-01

    The Kiel Long Duration Exposure Facility (LDEF) experiment M0002, mounted on experiment tray E6, was designed to measure the heavy ion environment by means of CR-39 plastic solid state track detectors. The detector stack with a size of 40x34x4.5 cu cm was exposed in vacuum covered by thermal protection foils with a total thickness of approx. 14 mg/sq cm. After etching small samples of the detector foils tracks with Z greater than or = 6 could be easily detected on a background of small etch pits, which were probably produced by secondaries from proton interactions. The LDEF orientation with respect to the magnetic field lines within the South Atlantic Anomaly (SAA) is expected to be constant during the mission. Therefore, the azimuth angle distribution was measured on the detector foils for low energy stopping particles. All detected arrival directions are close to a plane perpendicular to the magnetic field line of -20 deg declination and -40 deg inclination at location 34 deg W and 27 deg S. Together with the steep energy spectrum, this spatial distribution close to the mirror plane in the SAA is an evidence that heavy ions were detected from a radiation belt population.

  19. RELATIVISTIC HEAVY ION COLLISIONS: EXPERIMENT

    SciTech Connect

    Friedlander, Erwin M.; Heckman, Harry H.

    1982-04-01

    Relativistic heavy ion physics began as a 'no man's land' between particle and nuclear physics, with both sides frowning upon it as 'unclean', because on one hand, hadronic interactions and particle production cloud nuclear structure effects, while on the other, the baryonic environment complicates the interpretation of production experiments. They have attempted to review here the experimental evidence on RHI collisions from the point of view that it represents a new endeavor in the understanding of strong interaction physics. Such an approach appears increasingly justified; first, by the accumulation of data and observations of new features of hadronic interactions that could not have been detected outside a baryonic environment; second, by the maturation of the field owing to the advances made over the past several years in experimental inquiries on particle production by RHI, including pions, kaons, hyperons, and searches for antiprotons; and third, by the steady and progressive increase in the energy and mass ranges of light nuclear beams that have become available to the experiment; indeed the energy range has widened from the {approx} 0.2 to 2 AGeV at the Bevalac to {approx}4 AGeV at Dubna and recently, to the quantum jump in energies to {approx} 1000 equivalent AGeV at the CERN PS-ISR. Accompanying these expansions in the energy frontier are the immediate prospects for very heavy ion beams at the Bevalac up to, and including, 1 AGeV {sup 238}U, thereby extending the 'mass frontier' to its ultimate extent.

  20. SOLAR WIND TURBULENCE FROM MHD TO SUB-ION SCALES: HIGH-RESOLUTION HYBRID SIMULATIONS

    SciTech Connect

    Franci, Luca; Verdini, Andrea; Landi, Simone; Matteini, Lorenzo; Hellinger, Petr

    2015-05-10

    We present results from a high-resolution and large-scale hybrid (fluid electrons and particle-in-cell protons) two-dimensional numerical simulation of decaying turbulence. Two distinct spectral regions (separated by a smooth break at proton scales) develop with clear power-law scaling, each one occupying about a decade in wavenumbers. The simulation results simultaneously exhibit several properties of the observed solar wind fluctuations: spectral indices of the magnetic, kinetic, and residual energy spectra in the magnetohydrodynamic (MHD) inertial range along with a flattening of the electric field spectrum, an increase in magnetic compressibility, and a strong coupling of the cascade with the density and the parallel component of the magnetic fluctuations at sub-proton scales. Our findings support the interpretation that in the solar wind, large-scale MHD fluctuations naturally evolve beyond proton scales into a turbulent regime that is governed by the generalized Ohm’s law.

  1. High-resolution x-ray diffraction study of the heavy-fermion compound YbBiPt

    SciTech Connect

    Ueland, B. G.; Saunders, S. M.; Bud'ko, S. L.; Schmiedeshoff, G. M.; Canfield, P. C.; Kreyssig, A.; Goldman, A. I.

    2015-11-30

    In this study, YbBiPt is a heavy-fermion compound possessing significant short-range antiferromagnetic correlations below a temperature of T*=0.7K, fragile antiferromagnetic order below TN = 0.4K, a Kondo temperature of TK ≈ 1K, and crystalline-electric-field splitting on the order of E/kB = 1 – 10K. Whereas the compound has a face-centered-cubic lattice at ambient temperature, certain experimental data, particularly those from studies aimed at determining its crystalline-electric-field scheme, suggest that the lattice distorts at lower temperature. Here, we present results from high-resolution, high-energy x-ray diffraction experiments which show that, within our experimental resolution of ≈ 6 – 10 × 10–5 Å, no structural phase transition occurs between T = 1.5 and 50 K. In combination with results from dilatometry measurements, we further show that the compound's thermal expansion has a minimum at ≈ 18 K and a region of negative thermal expansion for 9 ≲ T ≲ 18 K. Despite diffraction patterns taken at 1.6 K which indicate that the lattice is face-centered cubic and that the Yb resides on a crystallographic site with cubic point symmetry, we demonstrate that the linear thermal expansion may be modeled using crystalline-electric-field level schemes appropriate for Yb3+ residing on a site with either cubic or less than cubic point symmetry.

  2. High-resolution x-ray diffraction study of the heavy-fermion compound YbBiPt

    DOE PAGES

    Ueland, B. G.; Saunders, S. M.; Bud'ko, S. L.; ...

    2015-11-30

    In this study, YbBiPt is a heavy-fermion compound possessing significant short-range antiferromagnetic correlations below a temperature of T*=0.7K, fragile antiferromagnetic order below TN = 0.4K, a Kondo temperature of TK ≈ 1K, and crystalline-electric-field splitting on the order of E/kB = 1 – 10K. Whereas the compound has a face-centered-cubic lattice at ambient temperature, certain experimental data, particularly those from studies aimed at determining its crystalline-electric-field scheme, suggest that the lattice distorts at lower temperature. Here, we present results from high-resolution, high-energy x-ray diffraction experiments which show that, within our experimental resolution of ≈ 6 – 10 × 10–5 Å,more » no structural phase transition occurs between T = 1.5 and 50 K. In combination with results from dilatometry measurements, we further show that the compound's thermal expansion has a minimum at ≈ 18 K and a region of negative thermal expansion for 9 ≲ T ≲ 18 K. Despite diffraction patterns taken at 1.6 K which indicate that the lattice is face-centered cubic and that the Yb resides on a crystallographic site with cubic point symmetry, we demonstrate that the linear thermal expansion may be modeled using crystalline-electric-field level schemes appropriate for Yb3+ residing on a site with either cubic or less than cubic point symmetry.« less

  3. In situ investigation of ion-induced dewetting of a thin iron-oxide film on silicon by high resolution scanning electron microscopy

    SciTech Connect

    Amirthapandian, S.; Schuchart, F.; Garmatter, D.; Bolse, W.

    2012-11-15

    Using our new in situ high resolution scanning electron microscope, which is integrated into the UNILAC ion beamline at the Helmholtzzentrum fuer Schwerionenforschung (GSI) in Darmstadt, Germany, we investigated the swift heavy ion induced dewetting of a thin iron oxide layer on Si. Besides heterogeneous hole nucleation at defects and spontaneous (homogeneous) hole nucleation, we could clearly identify a dewetting mechanism, which is similar to the spinodal dewetting observed for liquid films. Instead of being due to capillary waves, it is based on a stress induced surface instability. The latter results in the formation of a wavy surface with constant dominant wave-length and increasing amplitude during ion irradiation. Dewetting sets in as soon as the wave-troughs reach the film-substrate interface. Inspection of the hole radii and rim shapes indicates that removal of the material from the hole area occurs mainly by plastic deformation at the inner boundary and ion induced viscous flow in the peripheral zone due to surface tension.

  4. High-resolution fluence verification for treatment plan specific QA in ion beam radiotherapy

    NASA Astrophysics Data System (ADS)

    Martišíková, Mária; Brons, Stephan; Hesse, Bernd M.; Jäkel, Oliver

    2013-03-01

    Ion beam radiotherapy exploits the finite range of ion beams and the increased dose deposition of ions toward the end of their range in material. This results in high dose conformation to the target region, which can be further increased using scanning ion beams. The standard method for patient-plan verification in ion beam therapy is ionization chamber dosimetry. The spatial resolution of this method is given by the distance between the chambers (typically 1 cm). However, steep dose gradients created by scanning ion beams call for more information and improved spatial resolution. Here we propose a clinically applicable method, supplementary to standard patient-plan verification. It is based on ion fluence measurements in the entrance region with high spatial resolution in the plane perpendicular to the beam, separately for each energy slice. In this paper the usability of the RID256 L amorphous silicon flat-panel detector for the measurements proposed is demonstrated for carbon ion beams. The detector provides sufficient spatial resolution for this kind of measurement (pixel pitch 0.8 mm). The experiments were performed at the Heidelberg Ion-Beam Therapy Center in Germany. This facility is equipped with a synchrotron capable of accelerating ions from protons up to oxygen to energies between 48 and 430 MeV u-1. Beam application is based on beam scanning technology. The measured signal corresponding to single energy slices was translated to ion fluence on a pixel-by-pixel basis, using calibration, which is dependent on energy and ion type. To quantify the agreement of the fluence distributions measured with those planned, a gamma-index criterion was used. In the patient field investigated excellent agreement was found between the two distributions. At least 95% of the slices contained more than 96% of points agreeing with our criteria. Due to the high spatial resolution, this method is especially valuable for measurements of strongly inhomogeneous fluence

  5. High resolution extreme ultraviolet spectrometer for an electron beam ion trap

    SciTech Connect

    Ohashi, Hayato; Yatsurugi, Junji; Nakamura, Nobuyuki; Sakaue, Hiroyuki A.

    2011-08-15

    An extreme ultraviolet spectrometer has been developed for spectroscopic studies of highly charged ions with an electron beam ion trap. It has a slit-less configuration with a spherical varied-line-spacing grating that provides a flat focal plane for grazing incidence light. Alternative use of two different gratings enables us to cover the wavelength range 1-25 nm. Test observations with the Tokyo electron beam ion trap demonstrate the high performance of the present spectrometer such as a resolving power of above 1000.

  6. Laser ion source for low charge heavy ion beams

    SciTech Connect

    Okamura,M.; Pikin, A.; Zajic, V.; Kanesue, T.; Tamura, J.

    2008-08-03

    For heavy ion inertial fusion application, a combination of a laser ion source and direct plasma injection scheme into an RFQ is proposed. The combination might provide more than 100 mA of singly charged heavy ion beam from a single laser shot. A planned feasibility test with moderate current is also discussed.

  7. Heavy Flavor Dynamics in Relativistic Heavy-ion Collisions

    NASA Astrophysics Data System (ADS)

    Cao, Shanshan

    Heavy flavor hadrons serve as valuable probes of the transport properties of the quark-gluon plasma (QGP) created in relativistic heavy-ion collisions. In this dissertation, we introduce a comprehensive framework that describes the full-time evolution of heavy flavor in heavy-ion collisions, including its initial production, in-medium evolution inside the QGP matter, hadronization process from heavy quarks to their respective mesonic bound states and the subsequent interactions between heavy mesons and the hadron gas. The in-medium energy loss of heavy quarks is studied within the framework of a Langevin equation coupled to hydrodynamic models that simulate the space-time evolution of the hot and dense QGP matter. We improve the classical Langevin approach such that, apart from quasi-elastic scatterings between heavy quarks and the medium background, radiative energy loss is incorporated as well by treating gluon radiation as a recoil force term. The subsequent hadronization of emitted heavy quarks is simulated via a hybrid fragmentation plus recombination model. The propagation of produced heavy mesons in the hadronic phase is described using the ultra-relativistic quantum molecular dynamics (UrQMD) model. Our calculation shows that while collisional energy loss dominates the heavy quark motion inside the QGP in the low transverse momentum (p T) regime, contributions from gluon radiation are found to be significant at high pT. The recombination mechanism is important for the heavy flavor meson production at intermediate energies. The hadronic final state interactions further enhance the suppression and the collective flow of heavy mesons we observe. Within our newly developed framework, we present numerical results for the nuclear modification and the elliptic flow of D mesons, which are consistent with measurements at both the CERN Large Hadron Collider (LHC) and the BNL Relativistic Heavy-Ion Collider (RHIC); predictions for B mesons are also provided. In

  8. Annealing studies of cluster defects in ion-implanted silicon using high resolution DLTS

    NASA Astrophysics Data System (ADS)

    Gad, M. A.; Evans-Freeman, J. H.

    2006-12-01

    High resolution Laplace deep level transient spectroscopy (LDLTS) has been applied to investigate the annealing behaviour of small cluster defects in n-type Si. The Si was implanted with either Ge or Si, with energies 1500 keV and 850 keV respectively, and doses of 1 × 10 10 cm -2. The low dose ensured that there was a minimum of carrier removal due to deep defect states after implantation. Defect states in the as-implanted samples were attributed to VO pairs, divacancies and very small interstitial cluster defects, after detailed depth profiling. LDLTS of Ge + and Si + implanted silicon shows that there are three closely spaced deep levels associated with these clusters, with energies in the region of Ec-400 meV. Samples were then isochronally annealed in very small temperature intervals up to 560 K, in situ in our high temperature measurement cryostat, and the LDLTS re-examined as a function of annealing temperature. A new deeper energy level emerges as the cluster-related signal reduces, and it is suggested that this new trap is a major recombination centre, by comparison with current-voltage data.

  9. Targeted high-resolution ion mobility separation coupled to ultrahigh-resolution mass spectrometry of endocrine disruptors in complex mixtures.

    PubMed

    Benigni, Paolo; Thompson, Christopher J; Ridgeway, Mark E; Park, Melvin A; Fernandez-Lima, Francisco

    2015-04-21

    Traditional separation and detection of targeted compounds from complex mixtures from environmental matrices requires the use of lengthy prefractionation steps and high-resolution mass analyzers due to the large number of chemical components and their large structural diversity (highly isomeric). In the present work, selected accumulation trapped ion mobility spectrometry (SA-TIMS) is coupled to Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) for direct separation and characterization of targeted endocrine-disrupting compounds (EDC) from a complex environmental matrix in a single analysis. In particular, targeted identification based on high-resolution mobility (R ∼ 70-120) and ultrahigh-resolution mass measurements (R > 400 000) of seven commonly targeted EDC and their isobars (e.g., bisphenol A, (Z)- and (E)-diethylstilbestrol, hexestrol, estrone, α-estradiol, and 17-ethynylestradiol) is shown from a complex mixture of water-soluble organic matter (e.g., Suwannee River Fulvic Acid Standard II) complemented with reference standard measurements and theoretical calculations (<3% error).

  10. Focused ion beam high resolution grayscale lithography for silicon-based nanostructures

    SciTech Connect

    Erdmanis, M. Tittonen, I.

    2014-02-17

    Nanofabrication techniques providing a fine control over the profile of silicon structures are of great importance for nanophotonics, plasmonics, sensing, micro- and nano fluidics, and biomedical applications. We report on the applicability of focused ion beam for the fine grayscale lithography, which yields surface profiles that are customized at nanoscale. The approach is based on a correlation between the ion beam irradiation dose of inorganic resist and the mask etching rate in the reactive ion etching. An exceptional property of this method is the number of gray tones that are not limited by the resist characteristics. We apply the process to fabricate unique periodic nanostructures with a slope angle varying across the structure and a period as small as 200 nm.

  11. Laser ion source for high brightness heavy ion beam

    SciTech Connect

    Okamura, M.

    2016-09-01

    A laser ion source is known as a high current high charge state heavy ion source. But, we place great emphasis on the capability to realize a high brightness ion source. A laser ion source has a pinpoint small volume where materials are ionized and can achieve quite uniform low temperature ion beam. Those features may enable us to realize very small emittance beams. Furthermore, a low charge state high brightness laser ion source was successfully commissioned in Brookhaven National Laboratory in 2014. Now most of all the solid based heavy ions are being provided from the laser ion source for regular operation.

  12. Laser ion source for high brightness heavy ion beam

    DOE PAGES

    Okamura, M.

    2016-09-01

    A laser ion source is known as a high current high charge state heavy ion source. But, we place great emphasis on the capability to realize a high brightness ion source. A laser ion source has a pinpoint small volume where materials are ionized and can achieve quite uniform low temperature ion beam. Those features may enable us to realize very small emittance beams. Furthermore, a low charge state high brightness laser ion source was successfully commissioned in Brookhaven National Laboratory in 2014. Now most of all the solid based heavy ions are being provided from the laser ion sourcemore » for regular operation.« less

  13. Laser ion source for high brightness heavy ion beam

    SciTech Connect

    Okamura, M.

    2016-09-01

    A laser ion source is known as a high current high charge state heavy ion source. But, we place great emphasis on the capability to realize a high brightness ion source. A laser ion source has a pinpoint small volume where materials are ionized and can achieve quite uniform low temperature ion beam. Those features may enable us to realize very small emittance beams. Furthermore, a low charge state high brightness laser ion source was successfully commissioned in Brookhaven National Laboratory in 2014. Now most of all the solid based heavy ions are being provided from the laser ion source for regular operation.

  14. Laser ion source for high brightness heavy ion beam

    NASA Astrophysics Data System (ADS)

    Okamura, M.

    2016-09-01

    A laser ion source is known as a high current high charge state heavy ion source. However we place great emphasis on the capability to realize a high brightness ion source. A laser ion source has a pinpoint small volume where materials are ionized and can achieve quite uniform low temperature ion beam. Those features may enable us to realize very small emittance beams. In 2014, a low charge state high brightness laser ion source was successfully commissioned in Brookhaven National Laboratory. Now most of all the solid based heavy ions are being provided from the laser ion source for regular operation.

  15. Progress in Heavy Ion Fusion

    SciTech Connect

    Herrmannsfeldt, W.B.

    1988-09-01

    The progress of the field of Heavy Ion Fusion has been documented in the proceedings of the series of International Symposia that, in recent years, have occurred every second year. The latest of these conferences was hosted by Gesellshaft fuer Schwerionenforshung (GSI) in Darmstadt, West Germany, June 28-30, 1988. For this report, a few highlights from the conference are selected, stressing experimental progress and prospects for future advances. A little extra time is devoted to report on the developments at the Lawrence Berkeley Laboratory (LBL) which is the center for most of the HIFAR program. The Director of the HIFAR program at LBL is Denis Keefe, who presented the HIF report at the last two of the meetings in this series, and in whose place the author is appearing now. 4 refs., 1 fig.

  16. Highlights of the heavy ion fusion symposium

    SciTech Connect

    Keefe, D.

    1986-07-01

    The current status and prospects for inertial confinement fusion based on the use of intense beams of heavy ions will be described in the light of results presented at the International Symposium on Heavy Ion Fusion, (Washington, DC, May 27-29, 1986).

  17. Surface structure and lattice dynamics of KI(001) studied by high-resolution ion scattering combined with molecular dynamics simulation

    NASA Astrophysics Data System (ADS)

    Okazawa, T.; Nishimura, T.; Kido, Y.

    2002-09-01

    The rumpled surface structure and thermal lattice vibrations of KI(001) were studied by high-resolution medium-energy ion scattering (MEIS) and molecular dynamics (MD) simulation. The relaxation of the interlayer distance between the top and second layer and the rumpling of the top and second layers were measured directly by MEIS with an accuracy of 0.01 Å. From the displaced lattice positions determined above, we derived the dipole moments of the top- and second-layer K+ and I- ions self-consistently using the polalizabilities estimated from the optical refractive index combined with the Clausius-Mossotti relation. The balance between a short-range force and a long-range Coulombic one made it possible to judge the applicability of the short-range pair potentials proposed so far. We also determined the root-mean-square thermal vibration amplitudes of the bulk and top-layer ions together with the correlations between the top- and second-layer ions by means of the ion shadowing effect applied to various kinds of scattering geometries. The results obtained were compared with those calculated from the MD simulations based on a semiclassical model using the dipole moments determined above and a Born-Mayer- or Hellmann-type pair potential. The present results are in overall agreement with the MD simulations employing the pair potential proposed by Catlow et al. [J. Phys. C 10, 1395 (1977)].

  18. ION COMPOSITION ELUCIDATION (ICE): A HIGH RESOLUTION MASS SPECTROMETRIC TECHNIQUE FOR IDENTIFYING COMPOUNDS IN COMPLEX MIXTURES

    EPA Science Inventory

    When tentatively identifying compounds in complex mixtures using mass spectral libraries, multiple matches or no plausible matches due to a high level of chemical noise or interferences can occur. Worse yet, most analytes are not in the libraries. In each case, Ion Composition El...

  19. ION COMPOSITION ELUCIDATION (ICE): A HIGH RESOLUTION MASS SPECTROMETRIC TECHNIQUE FOR IDENTIFYING COMPOUNDS IN COMPLEX MIXTURES

    EPA Science Inventory

    When tentatively identifying compounds in complex mixtures using mass spectral libraries, multiple matches or no plausible matches due to a high level of chemical noise or interferences can occur. Worse yet, most analytes are not in the libraries. In each case, Ion Composition El...

  20. High-resolution determination of {sup 147}Pm in urine using dynamic ion-exchange chromatography

    SciTech Connect

    Elchuk, S.; Lucy, C.A.; Burns, K.I.

    1992-10-15

    Ion exchange preconcentration followed by HPLC purification prior to scintillation counting was used to measure the concentration of {sup 147}Pm in urine. the detection limit for this method was found to be 0.1 Bq (3 fg) of {sup 147}Pm in 500 ml of urine.

  1. The periodic focusing ion funnel: theory, design, and experimental characterization by high-resolution ion mobility-mass spectrometry.

    PubMed

    Fort, Kyle L; Silveira, Joshua A; Russell, David H

    2013-10-15

    Simulation-based development and experimental characterization of a DC-only ion funnel is described herein. Radial ion confinement is achieved via periodic focusing whereby a collisionally dampened effective potential is generated in the inertial frame of an ion traversing the device with appreciable velocity. The new device, termed a periodic focusing ion funnel (PF IF), provides an efficient alternative to the rf ion funnel providing high ion transmission with fewer electrodes, simplified electrical circuitry, and reduced power supply requirements. The utility of the PF IF for structural ion mobility-mass spectrometry (IM-MS) studies is demonstrated using model peptide ions (bradykinin, gramicidin S, and trpzip 1).

  2. High-resolution ion pulse ionization chamber with air filling for the 222Rn decays detection

    NASA Astrophysics Data System (ADS)

    Gavrilyuk, Yu. M.; Gangapshev, A. M.; Gezhaev, A. M.; Etezov, R. A.; Kazalov, V. V.; Kuzminov, V. V.; Panasenko, S. I.; Ratkevich, S. S.; Tekueva, D. A.; Yakimenko, S. P.

    2015-11-01

    The construction and characteristics of the cylindrical ion pulse ionization chamber (CIPIC) with a working volume of 3.2 L are described. The chamber is intended to register α-particles from the 222Rn and its daughter's decays in the filled air sample. The detector is less sensitive to electromagnetic pick-ups and mechanical noises. The digital pulse processing method is proposed to improve the energy resolution of the ion pulse ionization chamber. An energy resolution of 1.6% has been achieved for the 5.49 MeV α-line. The dependence of the energy resolution on high voltage and working media pressure has been investigated and the results are presented.

  3. Heavy Ion Fusion Accelerator Research (HIFAR)

    SciTech Connect

    Not Available

    1991-04-01

    This report discusses the following topics: emittance variations in current-amplifying ion induction lina; transverse emittance studies of an induction accelerator of heavy ions; drift compression experiments on MBE-4 and related emittance; low emittance uniform- density C{sub s}+ sources for heavy ion fusion accelerator studies; survey of alignment of MBE-4; time-of-flight dependence on the MBE-4 quadrupole voltage; high order calculation of the multiple content of three dimensional electrostatic geometries; an induction linac injector for scaled experiments; induction accelerator test module for HIF; longitudinal instability in HIF beams; and analysis of resonant longitudinal instability in a heavy ion induction linac.

  4. High-Resolution Differential Ion Mobility Separations Using Planar Analyzers at Elevated Dispersion Field

    PubMed Central

    Prior, David C.; Tang, Keqi; Smith, Richard D.

    2010-01-01

    The ion mobility spectrometry (IMS) methods are grouped into conventional IMS, based on the absolute ion mobility, and differential or field asymmetric waveform IMS (FAIMS), based on the mobility difference in strong and weak electric fields. A key attraction of FAIMS is substantial orthogonality to mass spectrometry (MS). Although several FAIMS/MS platforms were commercialized, their utility was limited by FAIMS resolving power, typically ∼10 - 20. Recently, gas mixtures comprising up to 75% He has enabled resolving power >100 that permits separation of numerous heretofore “co-eluting” isomers. This performance opens major new proteomic and other biological applications. Here, we show that raising the separation field by ∼35% over the previous 21 kV/cm provides similar or better resolution (with resolving powers of >200 for multiply-charged peptides) using only 50% He, which avoids problems due to elevated pressure and He content in the mass spectrometer. The heating of ions by the separation field in this regime exceeds that at higher He content but weaker field, inducing greater izomerization of labile species. PMID:20666414

  5. Moon originating heavy ions associated with CIR

    NASA Astrophysics Data System (ADS)

    Saito, Yoshifumi; Yokota, Shoichiro; Nishino, Masaki; Tsunakawa, Hideo

    2014-05-01

    Existance of a tenuous alkali atmosphere around the Moon was discovered by ground-based optical observations in 1980s. Since then the generation mechanism of the alkali atmosphere has been actively investigated. Currently, photon-stimulated desorption is regarded as the major generation process of the lunar alkai atmosphere such as sodium and potassium. MAP-PACE-IMA on Kaguya found four typical ion populations on the dayside of the Moon. These includes (1) solar wind protons backscattered at the lunar surface, (2) solar wind protons reflected by magnetic anomalies on the lunar surface, (3) reflected/backscattered protons picked-up by the solar wind, and (4) ions originating from the lunar surface/lunar exosphere. One of these populations: (4) ions originating from the lunar surface/lunar exosphere usually consisted of heavy ions such as carbon, oxygen, sodium, and potassium. Some of these ions were generated on the lunar surface by photon-stimulated desorption especially for alkali ions such as sodium and potassium and some others were generated by solar wind sputtering. Photo-ionized neutral particles were also included in these ions. These heavy ions were accelerated by the solar wind convection electric field and detected by the ion energy mass spectrometer MAP-PACE-IMA on Kaguya. Since the gyro-radius of these heavy ions was much larger than the Moon, the energy of these ions detected at 100km altitude was in most cases lower than the incident solar wind ion energy. Two special examples were found where the energy of the heavy ions was higher than the incident solar wind ion energy. These high-energy heavy ions were observed on the dayside of the Moon when CIR (Corotating Interaction Region) passed the Moon. The high energy heavy ions were observed for several hours with the highest heavy ion flux observed when the solar wind pressure increased due to the passage of the CIR. The mass spectrum of the heavy ions observed associated with CIR showed H+, He++, He

  6. Development of an Apparatus for High-Resolution Auger Photoelectron Coincidence Spectroscopy (APECS) and Electron Ion Coincidence (EICO) Spectroscopy

    NASA Astrophysics Data System (ADS)

    Kakiuchi, Takuhiro; Hashimoto, Shogo; Fujita, Narihiko; Mase, Kazuhiko; Tanaka, Masatoshi; Okusawa, Makoto

    We have developed an electron electron ion coincidence (EEICO) apparatus for high-resolution Auger photoelectron coincidence spectroscopy (APECS) and electron ion coincidence (EICO) spectroscopy. It consists of a coaxially symmetric mirror electron energy analyzer (ASMA), a miniature double-pass cylindrical mirror electron energy analyzer (DP-CMA), a miniature time-of-flight ion mass spectrometer (TOF-MS), a magnetic shield, an xyz stage, a tilt-adjustment mechanism, and a conflat flange with an outer diameter of 203 mm. A sample surface was irradiated by synchrotron radiation, and emitted electrons were energy-analyzed and detected by the ASMA and the DP-CMA, while desorbed ions were mass-analyzed and detected by the TOF-MS. The performance of the new EEICO analyzer was evaluated by measuring Si 2p photoelectron spectra of clean Si(001)-2×1 and Si(111)-7×7, and by measuring Si-L23VV-Si-2p Auger photoelectron coincidence spectra (Si-L23VV-Si-2p APECS) of clean Si(001)-2×1.

  7. High speed, high resolution, and continuous chemical analysis of ice cores using a melter and ion chromatography.

    PubMed

    Cole-Dai, Jihong; Budner, Drew M; Ferris, Dave G

    2006-11-01

    Measurement of trace chemical impurities in ice cores contributes to the reconstruction of records of the atmospheric environment and of the climate system. Ion chromatography (IC) is an effective analytical technique for ionic species in ice cores but has been used on discretely prepared ice samples, resulting in extensive and slow sample preparation and potential for contamination. A new technique has been developed that utilizes IC as the online detection technique in a melter-based continuous flow system for quantitative determination of major ionic chemical impurities. The system, called CFA-IC for continuous flow analysis with ion chromatography detection, consists of an ice core melter, several ion chromatographs, and an interface that distributes meltwater to the IC instruments. The CFA-IC technique combines the accuracy, precision, and ease of use of IC measurement with the enhanced speed and depth resolution of continuous melting systems and is capable of virtually continuous, high-speed and high-resolution chemical analysis of long ice cores. The new technique and operating procedures have been tested and validated with the analysis of over 100 m of ice cores from Antarctica. The current CFA-IC system provides an all-major-ion analysis speed of up to 8 m a day at a depth resolution of approximately 2 cm.

  8. A high-resolution pulsed-laser atom-probe field-ion microscope

    NASA Astrophysics Data System (ADS)

    Gorelikov, Dmitriy V.

    2001-10-01

    The atom-probe field-ion microscope is a unique instrument for the analysis of materials on an atom-by- atom and atomic layer-by-atomic layer basis. It combines a point projection microscope, which allows one to observe individual atoms in direct lattice space on the surface of a sharply pointed tip under a high positive voltage, with a time-of-flight mass spectrometer that can measure mass-to-charge ratios of individual atoms field- evaporated from the surface of a tip during a few nanosecond wide high-voltage or laser pulse. The ability to distinguish atomic isotopes and molecular clusters of one species from the other is crucial in the atom-probe analysis of multi-component materials. One of the main sources of errors in such an analysis is energy deficits of field-evaporated ions inherent to the pulsed high- voltage evaporation process. Therefore, in this study the task of designing and fabricating an atom-probe field-ion microscope capable of compensating these energy deficits, and versatile enough to be able to analyze a wide spectrum of engineering materials, was undertaken. The instrument has the following features: (a)ultrahigh vacuum (UHV); (b)a specimen exchange device that will store up to 10 specimens and allows transferring specimens directly from atmospheric pressure to UHV conditions; (c)a closed cycle helium refrigerator with a temperature regulator capable of cooling the specimen to 10 K; (d)a 3D goniometer with +/-30° tilt in the horizontal and vertical planes; (e)a variable distance, high gain MCP assembly for field-ion microscopy; (f)a single stage reflectron lens; (g)a 1500 Hz solid-state high voltage pulser; (h)a 20 Hz, 300 μJ/pulse, 4 ns pulsed nitrogen laser analysis capability. The mass resolution of this instrument is D(/) /= / at full-width half-maximum (FWHM) with high-voltage pulsing and D(/) /= / at FWHM with laser pulsing.

  9. High-resolution determination of 147Pm in urine using dynamic ion-exchange chromatography.

    PubMed

    Elchuk, S; Lucy, C A; Burns, K I

    1992-10-15

    A procedure has been developed for measuring 147Pm in bioassay samples, based on the separation and preconcentration of 147Pm from the urine matrix by adsorption onto a conventional cation-exchange column with final separation and purification by HPLC using dynamic ion-exchange chromatography. The concentration of 147Pm is determined by collecting the appropriate HPLC fraction and measuring the 147Pm by liquid scintillation counting. The limit of detection is 0.1 Bq (3 fg) 147Pm based on a 500-mL sample of urine and a counting time of 30 min with a background of 100 cpm. Ten samples can be processed in 1.5-2 days.

  10. Broad Separation of Isomeric Lipids by High-Resolution Differential Ion Mobility Spectrometry with Tandem Mass Spectrometry

    NASA Astrophysics Data System (ADS)

    Bowman, Andrew P.; Abzalimov, Rinat R.; Shvartsburg, Alexandre A.

    2017-08-01

    Maturation of metabolomics has brought a deeper appreciation for the importance of isomeric identity of lipids to their biological role, mirroring that for proteoforms in proteomics. However, full characterization of the lipid isomerism has been thwarted by paucity of rapid and effective analytical tools. A novel approach is ion mobility spectrometry (IMS) and particularly differential or field asymmetric waveform IMS (FAIMS) at high electric fields, which is more orthogonal to mass spectrometry. Here we broadly explore the power of FAIMS to separate lipid isomers, and find a 75% success rate across the four major types of glycero- and phospho- lipids ( sn, chain length, double bond position, and cis/ trans). The resolved isomers were identified using standards, and (for the first two types) tandem mass spectrometry. These results demonstrate the general merit of incorporating high-resolution FAIMS into lipidomic analyses.

  11. Superconducting heavy-ion accelerating structures

    SciTech Connect

    Shepard, K.W.

    1996-08-01

    This paper briefly reviews the technical history of superconducting ion-accelerating structures. Various superconducting cavities currently used and being developed for use in ion linacs are discussed. Principal parameters and operational characteristics of superconducting structures in active use at various heavy-ion facilities are described.

  12. Laser ion source for isobaric heavy ion collider experiment.

    PubMed

    Kanesue, T; Kumaki, M; Ikeda, S; Okamura, M

    2016-02-01

    Heavy-ion collider experiment in isobaric system is under investigation at Relativistic Heavy Ion Collider. For this experiment, ion source is required to maximize the abundance of the intended isotope. The candidate of the experiment is (96)Ru + (96)Zr. Since the natural abundance of particular isotope is low and composition of isotope from ion source depends on the composites of the target, an isotope enriched material may be needed as a target. We studied the performance of the laser ion source required for the experiment for Zr ions.

  13. Laser ion source for isobaric heavy ion collider experiment

    SciTech Connect

    Kanesue, T. Okamura, M.; Kumaki, M.; Ikeda, S.

    2016-02-15

    Heavy-ion collider experiment in isobaric system is under investigation at Relativistic Heavy Ion Collider. For this experiment, ion source is required to maximize the abundance of the intended isotope. The candidate of the experiment is {sup 96}Ru + {sup 96}Zr. Since the natural abundance of particular isotope is low and composition of isotope from ion source depends on the composites of the target, an isotope enriched material may be needed as a target. We studied the performance of the laser ion source required for the experiment for Zr ions.

  14. Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging

    PubMed Central

    Zanni, Giulia; Michno, Wojciech; Di Martino, Elena; Tjärnlund-Wolf, Anna; Pettersson, Jean; Mason, Charlotte Elizabeth; Hellspong, Gustaf; Blomgren, Klas; Hanrieder, Jörg

    2017-01-01

    Lithium (Li) is a potent mood stabilizer and displays neuroprotective and neurogenic properties. Despite extensive investigations, the mechanisms of action have not been fully elucidated, especially in the juvenile, developing brain. Here we characterized lithium distribution in the juvenile mouse brain during 28 days of continuous treatment that result in clinically relevant serum concentrations. By using Time-of-Flight Secondary Ion Mass Spectrometry- (ToF-SIMS) based imaging we were able to delineate temporospatial lithium profile throughout the brain and concurrent distribution of endogenous lipids with high chemical specificity and spatial resolution. We found that Li accumulated in neurogenic regions and investigated the effects on hippocampal neurogenesis. Lithium increased proliferation, as judged by Ki67-immunoreactivity, but did not alter the number of doublecortin-positive neuroblasts at the end of the treatment period. Moreover, ToF-SIMS revealed a steady depletion of sphingomyelin in white matter regions during 28d Li-treatment, particularly in the olfactory bulb. In contrast, cortical levels of cholesterol and choline increased over time in Li-treated mice. This is the first study describing ToF-SIMS imaging for probing the brain-wide accumulation of supplemented Li in situ. The findings demonstrate that this technique is a powerful approach for investigating the distribution and effects of neuroprotective agents in the brain. PMID:28098178

  15. Lithium Accumulates in Neurogenic Brain Regions as Revealed by High Resolution Ion Imaging.

    PubMed

    Zanni, Giulia; Michno, Wojciech; Di Martino, Elena; Tjärnlund-Wolf, Anna; Pettersson, Jean; Mason, Charlotte Elizabeth; Hellspong, Gustaf; Blomgren, Klas; Hanrieder, Jörg

    2017-01-18

    Lithium (Li) is a potent mood stabilizer and displays neuroprotective and neurogenic properties. Despite extensive investigations, the mechanisms of action have not been fully elucidated, especially in the juvenile, developing brain. Here we characterized lithium distribution in the juvenile mouse brain during 28 days of continuous treatment that result in clinically relevant serum concentrations. By using Time-of-Flight Secondary Ion Mass Spectrometry- (ToF-SIMS) based imaging we were able to delineate temporospatial lithium profile throughout the brain and concurrent distribution of endogenous lipids with high chemical specificity and spatial resolution. We found that Li accumulated in neurogenic regions and investigated the effects on hippocampal neurogenesis. Lithium increased proliferation, as judged by Ki67-immunoreactivity, but did not alter the number of doublecortin-positive neuroblasts at the end of the treatment period. Moreover, ToF-SIMS revealed a steady depletion of sphingomyelin in white matter regions during 28d Li-treatment, particularly in the olfactory bulb. In contrast, cortical levels of cholesterol and choline increased over time in Li-treated mice. This is the first study describing ToF-SIMS imaging for probing the brain-wide accumulation of supplemented Li in situ. The findings demonstrate that this technique is a powerful approach for investigating the distribution and effects of neuroprotective agents in the brain.

  16. Development of a High Resolution-High Sensitivity Ion Microprobe Facility for Cosmochemical Applications

    NASA Technical Reports Server (NTRS)

    McKeegan, Kevin D.

    1998-01-01

    NASA NAGW-4112 has supported development of the CAMECA ims 1270 ion microprobe at UCLA for applications in cosmochemistry. The instrument has been brought to an operational status and techniques developed for accurate, precise microbeam analysis of oxygen isotope ratios in polished thin-sections. We made the first oxygen isotopic (delta(18)O and delta(17)O) measurements of rare mafic silicates in the most chemically primitive meteorites, the a chondrites (Leshin et al., 1997). The results have implications for both high temperature processing in the nebula and low-T aqueous alteration on the CI asteroid. We have performed measurements of oxygen isotopic compositions of magnetite and co-existing olivine from carbonaceous (Choi et al., 1997) and unequilibrated ordinary chondrites (Choi et al., in press). This work has identified a significant new oxygen isotope reservoir in the early solar system: water characterized by a very high Delta(17)) value of approx. 5 % per thousand. We have determined the spatial distributions of oxygen isotopic anomalies in all major mineral phases of a type B CAI from Allende. We have also studied an unusual fractionated CAI from Leoville and made the first oxygen isotopic measurements in rare CAIs from ordinary chondrites.

  17. High resolution Coulomb explosion spectra and angular distributions of fragment ions of N 2 in a femtosecond laser field

    NASA Astrophysics Data System (ADS)

    Shi, Mingyuan; Huang, Shaochuan; Xi, Wei; Liu, Zuoye; Du, Hongchuan; Ding, Baowei; Hu, Bitao

    2017-03-01

    Femtosecond laser field-induced ionization and Coulomb explosion are systematically investigated using high-resolution time-of-flight mass spectroscopy. Meanwhile a good alignment of the N2 is achieved geometrically. Based on the energy and momentum conservation laws, the events from different Coulomb explosion channels are identified accurately and further used to obtain the Kinetic Energy Release (KER) by the created molecular ion pairs and the angular distributions of the fragment ions. The KERs measured at laser intensities varying from 4 × 10^{14} W/cm2 to 2 × 10^{15} W/cm2 are found to stay constant. The angular distributions are measured at laser intensity of 9 × 10^{14} W/cm2. The atomic ions N+, N^{2+} and N^{3+} exhibit highly anisotropic distributions and for higher charge state, the angular distributions become narrower. With good exclusion of channel N(1,0), the non-zeroes normal to the laser polarization vector in channel N(1,1) still exist, which indicates the presence of geometric alignments (GA). The elusive shrink structure at θ=0° for channels N(1,1), N(1,2) and N(2,3) is observed, which implies that the non-sequential process exists, and the electron rescattering plays role in the ionization process.

  18. Relativistic heavy ion fragmentation at HISS (Heavy Ion Spectrometer System)

    SciTech Connect

    Tull, C.E.

    1990-10-01

    An experiment was conducted at the Lawrence Berkeley Laboratory to measure projectile fragmentation of relativistic heavy ions. Charge identification was obtained by the use of a Cerenkov Hodoscope operating above the threshold for total internal reflection, while velocity measurement was performed by use of a second set of Cerenkov radiators operating at the threshold for total internal reflection. Charge and mass resolution for the system was {sigma}{sub Z} = 0.2 e and {sigma}{sub A} = 0.2 u. Measurements of the elemental and isotopic production cross sections for the fragmentation of {sup 40}Ar at 1.65{center dot}A GeV have been compared with an Abrasion-Ablation Model based on the evaporation computer code GEMINI. The model proves to be an accurate predictor of the cross sections for fragments between Chlorine and Boron. The measured cross section were reproduced using simple geometry with charge dispersions induced by zero-point vibrations of the giant dipole resonance for the prompt abrasion stage, and injecting an excitation energy spectrum based on a final state interaction with scaling factor E{sub fsi} = 38.8 MeV/c. Measurement of the longitudinal momentum distribution widths for projectile fragments are consistent with previous experiment and can be interpreted as reflecting the Fermi momentum distribution in the initial projectile nucleus. Measurement of the transverse momentum indicate an additional, unexplained dependence of the reduced momentum widths on fragment mass. This dependence has the same sign and similar slope to previously measured fragments of {sup 139}La, and to predictions based on phase-space constraints on the final state of the system.

  19. Electrospray ionization high-resolution ion mobility spectrometry for the detection of organic compounds, 1. Amino acids.

    PubMed

    Beegle, L W; Kanik, I; Matz, L; Hill, H H

    2001-07-01

    Our aim in this investigation was to demonstrate the potential of the high-resolution electrospray ionization ion mobility spectrometry (ESI-IMS) technique as an analytical separation tool in analyzing biomolecular mixtures to pursue astrobiological objectives of searching for the chemical signatures of life during an in-situ exploration of solar system bodies. Because amino acids represent the basic building blocks of life, we used common amino acids to conduct the first part of our investigation, which is being reported here, to demonstrate the feasibility of using the ESI-IMS technique for detection of the chemical signatures of life. The ion mobilities of common amino acids were determined by electrospray ionization ion mobility spectrometry using three different drift gases (N2, Ar, and CO2). We demonstrated that the selectivity can be vastly improved in ion mobility spectroscopy (IMS) in detecting organic molecules by using different drift gases. When a judicial choice of drift gas is made, a vastly improved separation of two different amino acid ions resulted. It was found that each of the studied amino acids could be uniquely identified from the others, with the exception of alanine and glycine, which were never separable by more then 0.1 ms. This unique identification is a result of the different polarizabilities of the various drift gases. In addition, a better separation was achieved by changing the drift voltage in successive experimental runs without significantly degrading the resolution. We also report the result of our analysis of liquid samples containing mixtures of amino acids.

  20. Achieving High Resolution Ion Mobility Separations Using Traveling Waves in Compact Multiturn Structures for Lossless Ion Manipulations

    SciTech Connect

    Hamid, Ahmed M.; Garimella, Sandilya V. B.; Ibrahim, Yehia M.; Deng, Liulin; Zheng, Xueyun; Webb, Ian K.; Anderson, Gordon A.; Prost, Spencer A.; Norheim, Randolph V.; Tolmachev, Aleksey V.; Baker, Erin S.; Smith, Richard D.

    2016-09-20

    We report on ion mobility separations (IMS) achievable using traveling waves in a Structures for Lossless Ion Manipulations (TW-SLIM) module having a 44-cm path length and sixteen 90º turns. The performance of the TW-SLIM module was evaluated for ion transmission, and ion mobility separations with different RF, TW parameters and SLIM surface gaps in conjunction with mass spectrometry. In this work TWs were created by the transient and dynamic application of DC potentials. The TW-SLIM module demonstrated highly robust performance and the ion mobility resolution achieved even with sixteen close spaced turns was comparable to a similar straight path TW-SLIM module. We found an ion mobility peak capacity of ~ 31 and peak generation rate of 780 s-1 for TW speeds of <210 m/s using the current multi-turn TW-SLIM module. The separations achieved for isomers of peptides and tetrasaccharides were found to be comparable to those from a ~ 0.9-m drift tube-based IMS-MS platform operated at the same pressure (4 torr). The combined attributes of flexible design, low voltage requirements and lossless ion transmission through multiple turns for the present TW-SLIM module provides a basis for SLIM devices capable of achieving much greater ion mobility resolutions via greatly extended ion path lengths and compact serpentine designs that do not significantly impact the instrumentation profile, a direction described in a companion manuscript.

  1. Heavy-Ion Fusion Accelerator Research, 1991

    SciTech Connect

    Not Available

    1992-03-01

    This report discusses the following topics: research with multiple- beam experiment MBE-4; induction linac systems experiments; and long- range research and development of heavy-ion fusion accelerators.

  2. Historical aspects of heavy ion radiotherapy

    SciTech Connect

    Raju, M.R.

    1995-03-01

    This paper presents historical developments of heavy-ion radiotherapy including discussion of HILAC and HIMAC and discussion of cooperation between Japan and the United States, along with personal reflections.

  3. Solenoid transport for heavy ion fusion

    SciTech Connect

    Lee, Edward

    2004-06-15

    Solenoid transport of high current, heavy ion beams is considered for several stages of a heavy ion fusion driver. In general this option is more efficient than magnetic quadrupole transport at sufficiently low kinetic energy and/or large e/m, and for this reason it has been employed in electron induction linacs. Ideally an ion beam would be transported in a state of Brillouin flow, i.e. cold in the transverse plane and spinning at one half the cyclotron frequency. The design of appropriate solenoids and the equilibrium and stability of transported ion beams are discussed. An outline of application to a fusion driver is also presented.

  4. Intermediate energy heavy ion reactions

    NASA Astrophysics Data System (ADS)

    Grégoire, C.; Tamain, B.

    The intermediate energy heavy ion induced reactions are extensively studied for several years. In this paper, we try to summarize the present knowledge. The peripheral reactions appear to be intermediate between the fragmentation and the deep inelastic regimes. Many questions remain open concerning the energy relaxation mechanisms and an eventual participant zone creation. In the case of central collisions, it has been shown that very hot nuclei can be built. The fusion limits are discussed and the very hot nuclei properties are considered. In some cases, hot spot formation or compression effects could play a role. Multifragmentation is discussed as a possible decay channel. In all these aspects, a difficult question concerns the validity of the temperature concept and more generally of collective thermodynamical variables. Such collective effects have been investigated in pion production experiments. Les réactions induites par ions lourds d'énergie intermédiaire sont très étudiées depuis quelques années. Dans cet article, nous essayons de résumer l'état actuel des connaissances. Les mécanismes mis en jeu dans les collisions périphériques sont intermédiaires entre les collisions très inélastiques et la fragmentation. La cible joue clairement un rôle déterminant et des effets importants de champ moyen demeurent. De nombreuses questions restent sans réponse comme par exemple les mécanismes de relaxation d'énergie ou l'existence d'une éventuelle zone participante. Dans le cas des collisions centrales, il a pu être montré que des noyaux très chauds sont fabriqués. Les limites au processus de fusion et les propriétés des noyaux très chauds sont discutées. Dans certains cas, des effets de compression ou de points chauds peuvent être envisagés. La multifragmentation est une voie de désexcitation possible. Une importante question concerne la validité du concept de température et plus généralement la notion de variable collective

  5. Wide-band, high-resolution soft x-ray spectrometer for the Electron Beam Ion Trap

    SciTech Connect

    Brown, G.V.; Beiersdorfer, P.; Widmann, K.

    1999-01-01

    We have constructed two wide-band, high-resolution vacuum flat crystal spectrometers and implemented them on the Electron Beam Ion Trap located at the Lawrence Livermore National Laboratory. Working in unison, these spectrometers can measure an x-ray bandwidth {le}9 {Angstrom} in the soft x-ray region below 21 {Angstrom}. In order to achieve this large bandwidth each spectrometer houses either two 125 mm {times} 13 mm {times} 2 mm RAP (rubidium acid phthalate, 2d=26.121 {Angstrom}), two 114 mm {times} 13 mm {times} 2 mm TlAP (thallium acid phthalate, 2d=25.75 {Angstrom}) crystals, or some combination thereof, for dispersion and two position sensitive proportional counters for detection of x rays. The spectrometers are used to measure wavelengths and relative intensities of the L-shell line emission from FethinspXVII{endash}XXIV for comparison with spectra obtained from astrophysical and laboratory plasmas. The wide wavelength coverage attainable by these spectrometers makes it possible to measure all the L-shell emission from a given iron ion species simultaneously. {copyright} {ital 1999 American Institute of Physics.}

  6. Jets in relativistic heavy ion collisions

    SciTech Connect

    Wang, Xin-Nian; Gyulassy, M.

    1990-09-01

    Several aspects of hard and semihard QCD jets in relativistic heavy ion collisions are discussed, including multiproduction of minijets and the interaction of a jet with dense nuclear matter. The reduction of jet quenching effect in deconfined phase of nuclear matter is speculated to provide a signature of the formation of quark gluon plasma. HIJING Monte Carlo program which can simulate events of jets production and quenching in heavy ion collisions is briefly described. 35 refs., 13 figs.

  7. New High Resolution Ion Mobility Mass Spectrometer Capable of Measurements of Collision Cross Sections from 150 to 520 K.

    PubMed

    Ujma, Jakub; Giles, Kevin; Morris, Michael; Barran, Perdita E

    2016-10-04

    We present a new variable temperature (VT), high resolution ion mobility (IM) drift tube coupled to a commercial mass spectrometer (MS). Ions are generated in an electrospray ion source with a sampling cone interface and two stacked ring RF guides which transfer ions into the mobility analyzer located prior to a quadrupole time-of-flight mass spectrometer. The drift cell can be operated over a pressure range of 0.5-3 Torr and a temperature range of 150-520 K with applied fields typically between 3 and 14 V cm(-1). This makes the instrument suitable for rotationally averaged collision cross section (CCS) measurements at low E/N ratios where ions are near thermal equilibrium with the buffer gas. Fundamental studies of the effective ion temperatures can be performed at high E/N ratios. An RF ion trap/buncher is located at the beginning of the drift region, which modulates the continuous ion beam into spatially narrow packets. Packets of ions then drift in a linear electric field, which is 50.5 cm long, and are separated according to their mobility in an inert buffer gas. Post-drift, an ion funnel focuses the radially spread pulses of ions into the inlet of a commercial MS platform (Micromass QToF2). We present the novel features of this instrument and results from VT-IM-MS experiments on a range of model systems-IMS CCS standards (Agilent ESI Tune Mix), the monomeric protein Ubiquitin (8.6 kDa), and the tetrameric protein complex Concanavalin A (103 kDa). We evaluate the performance of the instrument by comparing ambient (DT)CCSHe values of model compounds with those found in the literature. Several effects of temperature on collision cross sections and resolution are observed. For small rigid molecules, changes in resolution are consistent with anticipated thermal diffusion effects. Changes in measured (DT)CCSHe for these rigid systems at different temperatures are attributed primarily to the effect of temperature on the long-range attractive interaction. Similar

  8. Achieving High Resolution Ion Mobility Separations Using Traveling Waves in Compact Multiturn Structures for Lossless Ion Manipulations

    PubMed Central

    Ibrahim, Yehia M.; Deng, Liulin; Zheng, Xueyun; Webb, Ian K.; Anderson, Gordon A.; Prost, Spencer A.; Norheim, Randolph V.; Tolmachev, Aleksey V.; Baker, Erin S.; Smith, Richard D.

    2017-01-01

    We report on ion mobility (IM) separations achievable using traveling waves (TW) in a Structures for Lossless Ion Manipulations (SLIM) module having a 44 cm path length and 16 90° turns. The performance of the TW-SLIM module was evaluated for ion transmission and IM separations with different RF, TW parameters, and SLIM surface gaps in conjunction with mass spectrometry. In this work, TWs were created by the transient and dynamic application of DC potentials. The module demonstrated highly robust performance and, even with 16 closely spaced turns, achieving IM resolution performance and ion transmission comparable to a similar straight path module. We found an IM peak capacity of ~31 and peak generation rate of 780 s−1 for TW speeds of ~80 m/s using the current multi-turn TW-SLIM module. The separations achieved for isomers of peptides and tetrasaccharides were found to be comparable to those from a ~0.9-m drift tube-based IM-MS platform operated at the same pressure (4 Torr). The combined attributes of flexible design, low voltage requirements and lossless ion transmission through multiple turns for the present TW-SLIM module provides a basis for SLIM devices capable of achieving much greater IM resolution via greatly extended ion path lengths and using compact serpentine designs. PMID:27479234

  9. Achieving High Resolution Ion Mobility Separations Using Traveling Waves in Compact Multiturn Structures for Lossless Ion Manipulations.

    PubMed

    Hamid, Ahmed M; Garimella, Sandilya V B; Ibrahim, Yehia M; Deng, Liulin; Zheng, Xueyun; Webb, Ian K; Anderson, Gordon A; Prost, Spencer A; Norheim, Randolph V; Tolmachev, Aleksey V; Baker, Erin S; Smith, Richard D

    2016-09-20

    We report on ion mobility (IM) separations achievable using traveling waves (TW) in a Structures for Lossless Ion Manipulations (SLIM) module having a 44 cm path length and 16 90° turns. The performance of the TW-SLIM module was evaluated for ion transmission and IM separations with different RF, TW parameters, and SLIM surface gaps in conjunction with mass spectrometry. In this work, TWs were created by the transient and dynamic application of DC potentials. The module demonstrated highly robust performance and, even with 16 closely spaced turns, achieving IM resolution performance and ion transmission comparable to a similar straight path module. We found an IM peak capacity of ∼31 and peak generation rate of 780 s(-1) for TW speeds of ∼80 m/s using the current multi-turn TW-SLIM module. The separations achieved for isomers of peptides and tetrasaccharides were found to be comparable to those from a ∼0.9-m drift tube-based IM-MS platform operated at the same pressure (4 Torr). The combined attributes of flexible design, low voltage requirements and lossless ion transmission through multiple turns for the present TW-SLIM module provides a basis for SLIM devices capable of achieving much greater IM resolution via greatly extended ion path lengths and using compact serpentine designs.

  10. Calibration of the OHREX high-resolution imaging crystal spectrometer at the Livermore electron beam ion traps

    NASA Astrophysics Data System (ADS)

    Hell, N.; Beiersdorfer, P.; Magee, E. W.; Brown, G. V.

    2016-11-01

    We report the calibration of the Orion High-Resolution X-ray (OHREX) imaging crystal spectrometer at the EBIT-I electron beam ion trap at Livermore. Two such instruments, dubbed OHREX-1 and OHREX-2, are fielded for plasma diagnostics at the Orion laser facility in the United Kingdom. The OHREX spectrometer can simultaneously house two spherically bent crystals with a radius of curvature of r = 67.2 cm. The focusing properties of the spectrometer allow both for larger distance to the source due to the increase in collected light and for observation of extended sources. OHREX is designed to cover a 2.5°-3° spectral range at Bragg angles around 51.3°. The typically high resolving powers at these large Bragg angles are ideally suited for line shape diagnostics. For instance, the nominal resolving power of the instrument (>10 000) is much higher than the effective resolving power associated with the Doppler broadening due to the temperature of the trapped ions in EBIT-I. The effective resolving power is only around 3000 at typical EBIT-I conditions, which nevertheless is sufficient to set up and test the instrument's spectral characteristics. We have calibrated the spectral range for a number of crystals using well known reference lines in the first and second order and derived the ion temperatures from these lines. We have also made use of the 50 μm size of the EBIT-I source width to characterize the spatial focusing of the spectrometer.

  11. Calibration of the OHREX high-resolution imaging crystal spectrometer at the Livermore electron beam ion traps

    SciTech Connect

    Hell, N.; Beiersdorfer, P.; Magee, E. W.; Brown, G. V.

    2016-11-15

    We report the calibration of the Orion High-Resolution X-ray (OHREX) imaging crystal spectrometer at the EBIT-I electron beam ion trap at Livermore. Two such instruments, dubbed OHREX-1 and OHREX-2, are fielded for plasma diagnostics at the Orion laser facility in the United Kingdom. The OHREX spectrometer can simultaneously house two spherically bent crystals with a radius of curvature of r = 67.2 cm. The focusing properties of the spectrometer allow both for larger distance to the source due to the increase in collected light and for observation of extended sources. OHREX is designed to cover a 2.5°–3° spectral range at Bragg angles around 51.3°. The typically high resolving powers at these large Bragg angles are ideally suited for line shape diagnostics. For instance, the nominal resolving power of the instrument (>10 000) is much higher than the effective resolving power associated with the Doppler broadening due to the temperature of the trapped ions in EBIT-I. The effective resolving power is only around 3000 at typical EBIT-I conditions, which nevertheless is sufficient to set up and test the instrument’s spectral characteristics. We have calibrated the spectral range for a number of crystals using well known reference lines in the first and second order and derived the ion temperatures from these lines. We have also made use of the 50 μm size of the EBIT-I source width to characterize the spatial focusing of the spectrometer.

  12. Ultra-High Resolution Ion Mobility Separations Utilizing Traveling Waves in a 13 m Serpentine Path Length Structures for Lossless Ion Manipulations Module.

    PubMed

    Deng, Liulin; Ibrahim, Yehia M; Hamid, Ahmed M; Garimella, Sandilya V B; Webb, Ian K; Zheng, Xueyun; Prost, Spencer A; Sandoval, Jeremy A; Norheim, Randolph V; Anderson, Gordon A; Tolmachev, Aleksey V; Baker, Erin S; Smith, Richard D

    2016-09-20

    We report the development and initial evaluation of a 13 m path length Structures for Lossless Manipulations (SLIM) module for achieving high resolution separations using traveling waves (TW) with ion mobility (IM) spectrometry. The TW SLIM module was fabricated using two mirror-image printed circuit boards with appropriately configured RF, DC, and TW electrodes and positioned with a 2.75 mm intersurface gap. Ions were effectively confined in field-generated conduits between the surfaces by RF-generated pseudopotential fields and moved losslessly through a serpentine path including 44 "U" turns using TWs. The ion mobility resolution was characterized at different pressures, gaps between the SLIM surfaces, and TW and RF parameters. After initial optimization, the SLIM IM-MS module provided about 5-fold higher resolution separations than present commercially available drift tube or traveling wave IM-MS platforms. Peak capacity and peak generation rates achieved were 246 and 370 s(-1), respectively, at a TW speed of 148 m/s. The high resolution achieved in the TW SLIM IM-MS enabled, e.g., isomeric sugars (lacto-N-fucopentaose I and lacto-N-fucopentaose II) to be baseline resolved, and peptides from an albumin tryptic digest were much better resolved than with existing commercial IM-MS platforms. The present work also provides a foundation for the development of much higher resolution SLIM devices based upon both considerably longer path lengths and multipass designs.

  13. Ultra-High Resolution Ion Mobility Separations Utilizing Traveling Waves in a 13 m Serpentine Path Length Structures for Lossless Ion Manipulations Module

    SciTech Connect

    Deng, Liulin; Ibrahim, Yehia M.; Hamid, Ahmed M.; Garimella, Sandilya V. B.; Webb, Ian K.; Zheng, Xueyun; Prost, Spencer A.; Sandoval, Jeremy A.; Norheim, Randolph V.; Anderson, Gordon A.; Tolmachev, Aleksey V.; Baker, Erin S.; Smith, Richard D.

    2016-09-20

    We report the development and initial evaluation of a 13-m path length Structures for Lossless Manipulations (SLIM) module for achieving high resolution separations using traveling waves (TW) with ion mobility (IM) spectrometry. The TW SLIM module was fabricated using two mirror-image printed circuit boards with appropriately configured RF, DC and TW electrodes and positioned with a 2.75-mm inter-surface gap. Ions were effective confined between the surfaces by RF-generated pseudopotential fields and moved losslessly through a serpentine path including 44 “U” turns using TWs. The ion mobility resolution was characterized at different pressures, gaps between the SLIM surfaces, TW and RF parameters. After initial optimization the SLIM IM-MS module provided about 5-fold higher resolution separations than present commercially available drift tube or traveling wave IM-MS platforms. Peak capacity and peak generation rates achieved were 246 and 370 s-1, respectively, at a TW speed of 148 m/s. The high resolution achieved in the TW SLIM IM-MS enabled e.g., isomeric sugars (Lacto-N-fucopentaose I and Lacto-N-fucopentaose II) to be baseline resolved, and peptides from a albumin tryptic digest much better resolved than with existing commercial IM-MS platforms. The present work also provides a foundation for the development of much higher resolution SLIM devices based upon both considerably longer path lengths and multi-pass designs.

  14. The composition of heavy ions in solar energetic particle events

    NASA Technical Reports Server (NTRS)

    Fan, C. Y.; Gloeckler, G.; Hovestadt, D.

    1983-01-01

    Recent advances in determining the elemental, charge state, and isotopic composition of or approximate to 1 to or approximate to 20 MeV per nucleon ions in solar energetic particle (SEP) events and outline our current understanding of the nature of solar and interplanetary processes which may explain the observations. Average values of relative abundances measured in a large number of SEP events were found to be roughly energy independent in the approx. 1 to approx. 20 MeV per nucleon range, and showed a systematic deviation from photospheric abundances which seems to be organized in terms of the first ionization potential of the ion. Direct measurements of the charge states of SEPs revealed the surprisingly common presence of energetic He(+) along with heavy ion with typically coronal ionization states. High resolution measurements of isotopic abundance ratios in a small number of SEP events showed these to be consistent with the universal composition except for the puzzling overabundance of the SEP(22)Ne/(20)Ne relative to this isotopes ratio in the solar wind. The broad spectrum of observed elemental abundance variations, which in their extreme result in composition anomalies characteristic of (3)He rich, heavy ion rich and carbon poor SEP events, along with direct measurements of the ionization states of SEPs provided essential information on the physical characteristics of, and conditions in the source regions, as well as important constraints to possible models for SEP production.

  15. The heavy ion program at CERN

    SciTech Connect

    Lissauer, D.

    1986-09-30

    During two periods in 1986 and 1987, oxygen ion beams with energies up to 3.2 TeV will be available at the CERN-SPS. A brief review of the five large heavy ion experiments is presented and the different physics addressed by each of the experiments is discussed. 11 refs., 5 figs.

  16. Heavy-ion fusion accelerator research, 1989

    SciTech Connect

    Not Available

    1990-06-01

    This report discusses the following topics on heavy-ion fusion accelerator research: MBE-4: the induction-linac approach; transverse beam dynamics and current amplification; scaling up the results; through ILSE to a driver; ion-source and injector development; and accelerator component research and development.

  17. Propagation of heavy baryons in heavy-ion collisions

    NASA Astrophysics Data System (ADS)

    Das, Santosh K.; Torres-Rincon, Juan M.; Tolos, Laura; Minissale, Vincenzo; Scardina, Francesco; Greco, Vincenzo

    2016-12-01

    The drag and diffusion coefficients of heavy baryons (Λc and Λb ) in the hadronic phase created in the latter stage of the heavy-ion collisions at RHIC and LHC energies have been evaluated recently. In this work we compute some experimental observables, such as the nuclear suppression factor RA A and the elliptic flow v2 of heavy baryons at RHIC and LHC energies, highlighting the role of the hadronic phase contribution to these observables, which are going to be measured at Run 3 of LHC. For the time evolution of the heavy quarks in the quark and gluon plasma (QGP) and heavy baryons in the hadronic phase, we use the Langevin dynamics. For the hadronization of the heavy quarks to heavy baryons we employ Peterson fragmentation functions. We observe a strong suppression of both the Λc and Λb . We find that the hadronic medium has a sizable impact on the heavy-baryon elliptic flow whereas the impact of hadronic medium rescattering is almost unnoticeable on the nuclear suppression factor. We evaluate the Λc/D ratio at RHIC and LHC. We find that the Λc/D ratio remains unaffected due to the hadronic phase rescattering which enables it as a nobel probe of QGP phase dynamics along with its hadronization.

  18. Assignment of resonances in dissociative recombination of HD{sup +} ions: High-resolution measurements compared with accurate computations

    SciTech Connect

    Waffeu Tamo, F. O.; Buhr, H.; Schwalm, D.; Motapon, O.; Altevogt, S.; Andrianarijaona, V. M.; Grieser, M.; Lammich, L.; Lestinsky, M.; Motsch, M.; Novotny, S.; Orlov, D. A.; Pedersen, H. B.; Sprenger, F.; Weigel, U.; Wolf, A.; Nevo, I.; Urbain, X.; Schneider, I. F.

    2011-08-15

    The collision-energy resolved rate coefficient for dissociative recombination of HD{sup +} ions in the vibrational ground state is measured using the photocathode electron target at the heavy-ion storage ring TSR. Rydberg resonances associated with rovibrational excitation of the HD{sup +} core are scanned as a function of the electron collision energy with an instrumental broadening below 1 meV in the low-energy limit. The measurement is compared to calculations using multichannel quantum defect theory, accounting for rotational structure and interactions and considering the six lowest rotational energy levels as initial ionic states. Using thermal-equilibrium-level populations at 300 K to approximate the experimental conditions, close correspondence between calculated and measured structures is found up to the first vibrational excitation threshold of the cations near 0.24 eV. Detailed assignments, including naturally broadened and overlapping Rydberg resonances, are performed for all structures up to 0.024 eV. Resonances from purely rotational excitation of the ion core are found to have similar strengths as those involving vibrational excitation. A dominant low-energy resonance is assigned to contributions from excited rotational states only. The results indicate strong modifications in the energy dependence of the dissociative recombination rate coefficient through the rotational excitation of the parent ions, and underline the need for studies with rotationally cold species to obtain results reflecting low-temperature ionized media.

  19. Ultra Heavy Ion Collector (UHIC)

    NASA Technical Reports Server (NTRS)

    Stone, E. C.

    1997-01-01

    The purpose of this final report is to study the propagation of heavy nuclei in cosmic radiation. Topics include: Mass Distributions of Fragments from the Interactions of 600 MeV/n Silver Nuclei; Charge-pickup by Heavy Relativistic Nuclei; Fragmentation and Propagation Heavy UH Cosmic Ray Nuclei; Nuclear Fragmentation Parameters Needed for Interpretation of Observed Fluxes of UH Cosmic Ray Nuclei; Fragmentation and Electromagnetic Dissociation of 10.6 GeV/nucleon (197) Au Nuclei; Nuclear Interaction Cross Sections for UltraHeavy Nuclei; The Charge-Changing Fragmentation of 10.6 GeV/nucleon 197 Au Nuclei; Fragmentation Cross Sections of Relativistic 84/36 Kr and 109/47 Ag Nuclei in Targets from Hydrogen to Lead; Mission Concept for the Study of Ultraheavy Galactic Cosmic Rays; and Propagation of the Heaviest UH - Cosmic Ray Nuclei.

  20. Unraveling the origin of the complex structure of the thorium L γ x-ray lines in high-resolution spectra induced by heavy projectiles

    NASA Astrophysics Data System (ADS)

    Słabkowska, Katarzyna; Starosta, Joanna; WÈ©der, Ewa; Syrocki, Łukasz; Polasik, Marek

    2017-07-01

    The origin of the complex structure of L γ1 (L2N4 ), L γ2 (L1N2 ), L γ3 (L1N3 ), and L γ6 (L2O4 ) x-ray lines of thorium in high-resolution spectra induced by oxygen projectiles has so far resisted reliable quantitative interpretation. Therefore, the detailed structure predictions for satellite (additional holes in M ,N ,O , and/or P shells) and hypersatellite (additional hole in L shell) L γ x-ray lines of thorium being the results of extensive multiconfiguration Dirac-Fock calculations have been performed. Our predictions reproduce with the excellent precision the positions and shapes of characteristic parts of above high-resolution L γ x-ray spectrum of thorium what indicates that our study has been carried out with very high accuracy. The results of this study are the precursor for proper quantitative interpretation of the complex origin of L γ1,L γ2,L γ3 , and L γ6 lines in high-resolution x-ray spectra of thorium induced by different light and heavy projectiles.

  1. High energy heavy ions: techniques and applications

    SciTech Connect

    Alonso, J.R.

    1985-04-01

    Pioneering work at the Bevalac has given significant insight into the field of relativistic heavy ions, both in the development of techniques for acceleration and delivery of these beams as well as in many novel areas of applications. This paper will outline our experiences at the Bevalac; ion sources, low velocity acceleration, matching to the synchrotron booster, and beam delivery. Applications discussed will include the observation of new effects in central nuclear collisions, production of beams of exotic short-lived (down to 1 ..mu..sec) isotopes through peripheral nuclear collisions, atomic physics with hydrogen-like uranium ions, effects of heavy ''cosmic rays'' on satellite equipment, and an ongoing cancer radiotherapy program with heavy ions. 39 refs., 6 figs., 1 tab.

  2. Heavy-ion irradiation induced diamond formation in carbonaceous materials.

    SciTech Connect

    Daulton, T. L.

    1999-01-08

    The basic mechanisms of metastable phase formation produced under highly non-equilibrium thermodynamic conditions within high-energy particle tracks are investigated. In particular, the possible formation of diamond by heavy-ion irradiation of graphite at ambient temperature is examined. This work was motivated, in part, by earlier studies which discovered nanometer-grain polycrystalline diamond aggregates of submicron-size in uranium-rich carbonaceous mineral assemblages of Precambrian age. It was proposed that the radioactive decay of uranium formed diamond in the fission particle tracks produced in the carbonaceous minerals. To test the hypothesis that nanodiamonds can form by ion irradiation, fine-grain polycrystalline graphite sheets were irradiated with 400 MeV Kr ions. The ion irradiated graphite (and unirradiated graphite control) were then subjected to acid dissolution treatments to remove the graphite and isolate any diamonds that were produced. The acid residues were then characterized by analytical and high-resolution transmission electron microscopy. The acid residues of the ion-irradiated graphite were found to contain ppm concentrations of nanodiamonds, suggesting that ion irradiation of bulk graphite at ambient temperature can produce diamond.

  3. Effect of length scale tuning of background Error in WRF-3DVAR system on assimilation of high-resolution surface data for heavy rainfall simulation

    NASA Astrophysics Data System (ADS)

    Ha, Ji-Hyun; Lee, Dong-Kyou

    2012-11-01

    We investigated the impact of tuning the length scale of the background error covariance in the Weather Research and Forecasting (WRF) three-dimensional variational assimilation (3DVAR) system. In particular, we studied the effect of this parameter on the assimilation of high-resolution surface data for heavy rainfall forecasts associated with mesoscale convective systems over the Korean Peninsula. In the assimilation of high-resolution surface data, the National Meteorological Center method tended to exaggerate the length scale that determined the shape and extent to which observed information spreads out. In this study, we used the difference between observation and background data to tune the length scale in the assimilation of high-resolution surface data. The resulting assimilation clearly showed that the analysis with the tuned length scale was able to reproduce the small-scale features of the ideal field effectively. We also investigated the effect of a double-iteration method with two different length scales, representing large and small-length scales in the WRF-3DVAR. This method reflected the large and small-scale features of observed information in the model fields. The quantitative accuracy of the precipitation forecast using this double iteration with two different length scales for heavy rainfall was high; results were in good agreement with observations in terms of the maximum rainfall amount and equitable threat scores. The improved forecast in the experiment resulted from the development of well-identified mesoscale convective systems by intensified low-level winds and their consequent convergence near the rainfall area.

  4. Light and heavy ion beam analysis of thin biological sections

    NASA Astrophysics Data System (ADS)

    Lee, Joonsup; Siegele, Rainer; Pastuovic, Zeljko; Hackett, Mark J.; Hunt, Nicholas H.; Grau, Georges E.; Cohen, David D.; Lay, Peter A.

    2013-07-01

    The application of ion beam analysis (IBA) techniques to thin biological sections (ThBS) presents unique challenges in sample preparation, data acquisition and analysis. These samples are often the end product of expensive, time-consuming experiments, which involve many steps that require careful attention. Analysis via several techniques can maximise the information that is collected from these samples. Particle-induced X-ray emission (PIXE) and Rutherford backscattering (RBS) spectroscopy are two generally non-destructive IBA techniques that use the same MeV ions and can be performed simultaneously. The use of heavy ion PIXE applied to thick samples has, in the past, resulted in X-ray spectra of a poorer quality when compared to those obtained with proton beams. One of the reasons for this is the shorter probing depth of the heavy ions, which does not affect thin sample analysis. Therefore, we have investigated and compared 3-MeV proton and 36-MeV carbon ion beams on 7-μm thick mouse brain sections at the ANSTO Heavy ion microprobe (HIMP). The application of a 36-MeV C4+ ion beam for PIXE mapping of ThBS on thin Si3N4 substrate windows produced spectra of high quality that displayed close to a nine-times gain in signal yield (Z2/q) when compared to those obtained for 3-MeV protons for P, S, Cl and K but not for Fe, Cu and Zn. Image quality was overall similar; however, some elements showed better contrast and features with protons whilst others showed improved contrast with a carbon ion beam. RBS spectra with high enough counting statistics were easily obtained with 3-MeV proton beams resulting in high resolution carbon maps, however, the count rate for nitrogen and oxygen was too low. The results demonstrate that on thin samples, 36-MeV C4+ will produce good quality PIXE spectra in less time; therefore, carbon ions may be advantageous depending on which element is being studied. However, these advantages may be outweighed by the inherent disadvantages including

  5. Irradiation of a tin oxide nanometric powder with swift heavy ions

    NASA Astrophysics Data System (ADS)

    Berthelot, A.; Gourbilleau, F.; Dufour, C.; Domengès, B.; Paumier, E.

    2000-05-01

    Tin oxide nanometric powders have been irradiated with swift heavy ions (Ar, Cd, Ta, Pb and U) and observed by high resolution electron microscopy (HREM). Except for Ar ions, cylindrical tracks are visible. The mean track radius is all the more important since the electronic stopping power Se is high. Furthermore, the high-Se ions (Ta, Pb and U) create cylindrical holes, while in the case of Cd irradiations, a crystal-like contrast remains in the core track. Cylindrical holes correspond to a local zone where the maximum temperature calculated using the thermal spike model exceeds the boiling point. For Cd ion irradiations, a sputtering process is investigated.

  6. Serpentine Ultralong Path with Extended Routing (SUPER) High Resolution Traveling Wave Ion Mobility-MS using Structures for Lossless Ion Manipulations.

    PubMed

    Deng, Liulin; Webb, Ian K; Garimella, Sandilya V B; Hamid, Ahmed M; Zheng, Xueyun; Norheim, Randolph V; Prost, Spencer A; Anderson, Gordon A; Sandoval, Jeremy A; Baker, Erin S; Ibrahim, Yehia M; Smith, Richard D

    2017-04-05

    Ion mobility (IM) separations have a broad range of analytical applications, but insufficient resolution often limits their utility. Here, we report on ion mobility separations in a structures for lossless ion manipulations (SLIM) serpentine ultralong path with extended routing (SUPER) traveling wave (TW) ion mobility (IM) module in conjunction with mass spectrometry (MS). Ions were confined in the SLIM by rf fields in conjunction with a DC guard bias, enabling essentially lossless TW transmission over greatly extended paths. The extended routing utilized multiple passes (e.g., ∼1094 m over 81 passes through the 13.5 m serpentine path) and was facilitated by the introduction of a lossless ion switch that allowed ions to be directed to either the MS detector or for another pass through the serpentine separation region, allowing theoretically unlimited IM path lengths. The multipass SUPER IM-MS provided resolution approximately proportional to the square root of the number of passes (or total path length). More than 30-fold higher IM resolution (∼340 vs ∼10) for Agilent tuning mix m/z 622 and 922 ions was achieved for 40 passes compared to commercially available drift tube IM and other TWIM-based platforms. An initial evaluation of the isomeric sugars lacto-N-hexaose and lacto-N-neohexaose showed the isomeric structures to be baseline resolved, and a new conformational feature for lacto-N-neohexaose was revealed after 9 passes. The new SLIM SUPER high resolution TWIM platform has broad utility in conjunction with MS and is expected to enable a broad range of previously challenging or intractable separations.

  7. Polarization in heavy-ion reactions. [Lectures

    SciTech Connect

    Fick, D.

    1983-08-01

    Determination of the polarization and spin alignment of reaction products emitted from heavy ion reactions should provide a sensitive test of reaction mechanisms. Techniques for producing both polarized beams and polarized targets are advancing rapidly. At the Oak Ridge National Laboraotry interest in this field has lead to the design and construction of a laser optically pumped polarized target by illuminating a supersonic gas jet. This target, which is mounted in the scattering chamber of a magnetic spectrometer, will be used to observe effects when deformed polarized targets are bombarded by heavy ions. Mutual research interests led to the invitation of Professor Fick, a pioneer in heavy ion polarization research who recently reviewed the status of this field, to Oak Ridge. While at ORNL he presented a series of lectures on this subject. Notes from these lectures are presented. (WHK)

  8. Heavy-Ion Imaging Applied To Medicine

    NASA Astrophysics Data System (ADS)

    Fabrikant, J. I.; Tobias, C. A.; Capp, M. P.; Benton, E. V.; Holley, W. R.

    1980-08-01

    Heavy particle radiography is a newly developed noninvasive low dose imaging procedure with increased resolution of minute density differences in soft tissues of the body. The method utilizes accelerated high energy ions, primarily carbon and neon, at the BEVALAC accelerator at the Lawrence Berkeley Laboratory. The research program applied to medicine utilizes heavy-ion radiography for low dose mammography, for treatment planning for cancer patients, and for imaging and accurate densitometry of skeletal structures and brain and spinal neoplasms. The presentation will be illustrated with clinical cases under study. Discussion will include the potential of heavy-ion imaging, and particularly reconstruction tomography, as an adjunct to existing diagnostic imaging procedures in medicine, both for the applications to the diagnosis, management and treatment of clinical cancer in man, but also for the early detection of small soft tissue tumors at low radiation dose.

  9. Data acquisition for the HILI (Heavy Ion Light Ion) detector

    SciTech Connect

    Teh, K.M.; Shapira, D.; McConnell, J.W.; Kim, H.; Novotny, R.

    1987-01-01

    A large acceptance, multi-segmented detector system capable of the simultaneous detection of heavy and light ions has been constructed. The heavy ions are detected with a segmented gas ionization chamber and a multiwire proportional counter while the light ions are detected with a 192 element plastic phoswich hodoscope. Processing the large number of signals is accomplished through a combination of CAMAC and FASTBUS modules and preprocessors, and a Host minicomputer. Details of the data acquisition system and the reasons for adopting a dual standards system are discussed. In addition, a technique for processing signals from an individual hodoscope detector is presented. 4 refs., 3 figs.

  10. Pair creation in heavy ion channeling

    NASA Astrophysics Data System (ADS)

    Belov, N. A.; Harman, Z.

    2016-04-01

    Heavy ions channeled through crystals with multi-GeV kinetic energies can create electron-positron pairs. In the framework of the ion, the energy of virtual photons arising from the periodic crystal potential may exceed the threshold 2mec2. The repeated periodic collisions with the crystal ions yield high pair production rates. When the virtual photon frequency matches a nuclear transition in the ion, the production rate can be resonantly increased. In this two-step excitation-pair conversion scheme, the excitation rates are coherently enhanced, and scale approximately quadratically with the number of crystal sites along the channel.

  11. Jets In Heavy Ion Collisions with CMS

    NASA Astrophysics Data System (ADS)

    Salur, Sevil

    2016-08-01

    Jet physics in heavy ion collisions is a rich field which has been rapidly evolving since the first observations of medium interactions at RHIC through back-to-back hadron correlations and at LHC via reconstructed jets. In order to completely characterize the final state via jet-medium interactions and distinguish between competing energy loss mechanisms, complementary and robust jet observables are investigated. Latest developments of jet finding techniques and their applications to heavy ion environments are discussed with an emphasis given on experimental results from CMS experiment.

  12. Angular spectrum analysis in heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Llanes-Estrada, Felipe J.; Muñoz Martínez, Jose L.

    2017-01-01

    Heavy Ion Collisions serve to study some features of early-universe cosmology. In this contribution we adapt data analysis frequently used to understand the Cosmic Microwave Background anisotropies (such as the Mollweide projection and the angular power spectrum) to heavy ion collisions at the LHC. We examine a few publicly available events of the ALICE collaboration under this light. Because the ALICE time projection chamber has limited coverage in rapidity and some blind angles in the transverse plane, the angular spectrum seems very influenced by the detector's acceptance.

  13. Induction linacs for heavy ion fusion

    SciTech Connect

    Keefe, D.

    1986-11-01

    Experimental progress to date has strengthened our belief in the soundness and attractiveness of the heavy ion method for fusion. What surprises that have shown up in the laboratory (e.g., in SBTE) have all been of the pleasant kind so far. The systems assessment has supported the view that the heavy ion approach can lead to economically attractive electric power and that a wide variety of options exists in all parameters. The systems work has also been of great help in pointing the way for the research and development activities.

  14. Holographic heavy ion collisions with baryon charge

    SciTech Connect

    Casalderrey-Solana, Jorge; Mateos, David; van der Schee, Wilke; Triana, Miquel

    2016-09-19

    We numerically simulate collisions of charged shockwaves in Einstein-Maxwell theory in anti-de Sitter space as a toy model of heavy ion collisions with non-zero baryon charge. The stress tensor and the baryon current become well described by charged hydrodynamics at roughly the same time. The effect of the charge density on generic observables is typically no larger than 15%. Finally, we find significant stopping of the baryon charge and compare our results with those in heavy ion collision experiments.

  15. New developments in heavy ion fusion

    SciTech Connect

    Herrmannsfeldt, W.B.

    1983-04-01

    Beginning in 1984, the US Department of Energy plans a program aimed at determining the feasibility of using heavy ion accelerators as pellet drivers for Inertial Confinement Fusion (ICF). This paper will describe the events in the field of Heavy Ion Fusion (HIF) that have occurred in the three years since the Lausanne conference in this series. The emphasis will be on the events leading towards the new energy oriented program. in addition to providing an overview of progress in HIF, such a discussion may prove useful for promoters of any emerging energy technology.

  16. Holographic heavy ion collisions with baryon charge

    NASA Astrophysics Data System (ADS)

    Casalderrey-Solana, Jorge; Mateos, David; van der Schee, Wilke; Triana, Miquel

    2016-09-01

    We numerically simulate collisions of charged shockwaves in Einstein-Maxwell theory in anti-de Sitter space as a toy model of heavy ion collisions with non-zero baryon charge. The stress tensor and the baryon current become well described by charged hydrodynamics at roughly the same time. The effect of the charge density on generic observables is typically no larger than 15%. We find significant stopping of the baryon charge and compare our results with those in heavy ion collision experiments.

  17. Characteristic X-ray production in heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Kiisk, Madis; Persson, Per; Hellborg, Ragnar; Smit, Ziga; Erlandsson, Bengt; Faarinen, Mikko; Skog, Göran; Stenström, Kristina

    2000-10-01

    The characteristic K X-ray production from projectile and solid target atoms in heavy ion collisions have been measured using a high-resolution Ge-detector. Ni projectiles in the energy range 15-25 MeV have been used to irradiate various thick targets made of materials in the Z range 22-32. In this energy region, the transition from predominantly quasi-molecular excitation to predominantly Coulomb excitation occurs. These measurements have been done in connection with our programme with a fairly new analytical technique, a combination of accelerator mass spectrometry (AMS) and the detection of characteristic X-rays. From the measurements, experimental K X-ray cross-sections have been extracted. Comparisons with other experimental data as well as with theoretical values are presented.

  18. Biomedical research with heavy ions at the IMP accelerators

    NASA Astrophysics Data System (ADS)

    Li, Qiang

    The main ion-beam acceleration facilities and research activities at the Institute of Modern Physics (IMP), Chinese Academy of Sciences are briefly introduced. Some of the biomedical research with heavy ions such as heavy-ion biological effect, basic research related to heavy-ion cancer therapy and radiation breeding at the IMP accelerators are presented.

  19. Design status of heavy ion injector program

    SciTech Connect

    Ballard, E.O.; Meyer, E.A.; Rutkowski, H.L.; Shurter, R.P.; Van Haaften, F.W.; Riepe, K.B.

    1985-01-01

    Design and development of a sixteen beam, heavy ion injector is in progress at Los Alamos National Laboratory (LANL) to demonstrate the injector technology for the High Temperature Experiment (HTE) proposed by Lawrence Livermore Laboratory (LBL). The injector design provides for individual ion sources mounted to a support plate defining the sixteen beam array. The beamlets are electrostatically accelerated through a series of electrodes inside an evacuated (10/sup -7/ torr) high voltage (HV) accelerating column.

  20. Design status of heavy ion injector program

    NASA Astrophysics Data System (ADS)

    Ballard, E. O.; Meyer, E. A.; Rutkowski, H. L.; Shurter, R. P.; Vanhaaften, F. W.; Riepe, K. B.

    1985-05-01

    Design and development of a sixteen beam, heavy ion injector is in progress at Los Alamos National Laboratory (LANL) to demonstrate the injector technology for the High Temperature Experiment (HTE) proposed by Lawrence Livermore Laboratory (LBL). The injector design provides for individual ion sources mounted to a support plate defining the sixteen beam array. The beamlets are electrostatically accelerated through a series of electrodes inside an evacuate 10 to the minus 7th power torr high voltage (HV) accelerating column.

  1. Heavy quarkonium photoproduction in ultrarelativistic heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Yu, Gong-Ming; Cai, Yang-Bing; Li, Yun-De; Wang, Jian-Song

    2017-01-01

    Based on the factorization formalism of nonrelativistic quantum chromodynamics (NRQCD), we calculate the production cross section for the charmonium [J /ψ , ψ (2 S ) , χc J, ηc, and hc] and the bottomonium [Υ (n S ) , χb J, ηb, and hb] produced by the hard photoproduction processes and fragmentation processes in relativistic heavy ion collisions. It is shown that the existing experimental data on heavy quarkonium production at the Large Hadron Collider (LHC) can be described in the framework of the NRQCD formalism, and the phenomenological values of matrix elements for color-singlet and color-octet components give the main contribution. The numerical results of photoproduction processes and fragmentation processes for the heavy quarkonium production become prominent in p -p collisions and Pb-Pb collisions at LHC energies.

  2. Heavy ion driven LMF design concept

    SciTech Connect

    Lee, E.P.

    1991-08-01

    The USA Department of Energy has conducted a multi-year study of the requirements, designs and costs for a Laboratory Microfusion Facility (LMF). The primary purpose of the LMF would be testing of weapons physics and effects simulation using the output from microexplosions of inertial fusion pellets. It does not need a high repetition rate, efficient driver system as required by an electrical generating plant. However there would be so many features in common that the design, construction and operation of an LMF would considerably advance the application of inertial confinement fusion to energy production. The DOE study has concentrated particularly on the LMF driver, with design and component development undertaken at several national laboratories. Principally, these are LLNL (Solid State Laser), LANL (Gas Laser), and SNLA (Light Ions). Heavy Ions, although considered a possible LMF driver did not receive attention until the final stages of this study since its program management was through the Office of Energy Research rather than Defense Programs. During preparation of a summary report for the study it was decided that some account of heavy ions was needed for a complete survey of the driver candidates. A conceptual heavy ion LMF driver design was created for the DOE report which is titled LMC Phase II Design Concepts. The heavy ion driver did not receive the level of scrutiny of the other concepts and, unlike the others, no costs analysis by an independent contractor was performed. Since much of heavy ion driver design lore was brought together in this exercise it is worthwhile to make it available as an independent report. This is reproduced here as it appears in the DOE report.

  3. Heavy ion driven LMF design concept

    NASA Astrophysics Data System (ADS)

    Lee, E. P.

    1991-08-01

    The US Department of Energy has conducted a multi-year study of the requirements, designs and costs for a Laboratory Microfusion Facility (LMF). The primary purpose of the LMF would be testing of weapons physics and effects simulation using the output from microexplosions of inertial fusion pellets. It does not need a high repetition rate, efficient driver system as required by an electrical generating plant. However there would be so many features in common that the design, construction and operation of an LMF would considerably advance the application of inertial confinement fusion to energy production. The DOE study has concentrated particularly on the LMF driver, with design and component development undertaken at several national laboratories. Principally, these are LLNL (Solid State Laser), LANL (Gas Laser), and SNLA (Light Ions). Heavy Ions, although considered a possible LMF driver did not receive attention until the final stages of this study since its program management was through the Office of Energy Research rather than Defense Programs. During preparation of a summary report for the study it was decided that some account of heavy ions was needed for a complete survey of the driver candidates. A conceptual heavy ion LMF driver design was created for the DOE report which is titled LMC Phase II Design Concepts. The heavy ion driver did not receive the level of scrutiny of the other concepts and, unlike the others, no costs analysis by an independent contractor was performed. Since much of heavy ion driver design lore was brought together in this exercise it is worthwhile to make it available as an independent report. This is reproduced here as it appears in the DOE report.

  4. High resolution of anthropogenic atmospheric emissions of 12 heavy metals in the three biggest metropolitan areas, China

    NASA Astrophysics Data System (ADS)

    Tian, H.; Zhu, C.

    2015-12-01

    Atmospheric emissions of typical toxic heavy metals from anthropogenic sources have received worldwide concerns due to their adverse effects on human health and the ecosystem. An integrated inventory of anthropogenic emissions of twelve HMs (Hg, As, Se, Pb, Cd, Cr, Ni, Sb, Mn, Co, Cu and Zn) in the three biggest metropolitan areas, including Beijing-Tianjin-Hebei (BTH) region, Yangtze River Delta (YRD) region and Pearl River Delta (PRD) region, are developed for 1980-2012 by combining with detailed activity data and inter-annual dynamic emission factors which are determined by S-shaped curves on account of technology progress, economic development, and emission control. The results indicate total emissions of twelve HMs in the three metropolitan regions have increased from 5448.8 tons in 1980 to 19054.9 tons in 2012, with an annual average growth rate of about 4.0%. Due to significant difference in industrial structures and energy consumption compositions, remarkable distinctions can be observed with respect to source contributions of total HM emissions from above three metropolitan areas. Specifically, the ferrous metal smelting sector, coal combustion by industrial boilers and coal combustion by power plants are found to be the primary source of total HM emissions in the BTH region (about 34.2%), YRD region (about 28.2%) and PRD region (about 24.3%), respectively. Furthermore, we allocate the annual emissions of these heavy metals in 2012 at a high spatial resolution of 9 km × 9 km grid with ArcGIS methodology and surrogate indexes, such as regional population and gross domestic product (GDP). The peak of HM emissions are mainly distributed over the grid cells of Beijing, Tianjin, Tangshan, Shijiazhuang, Handan and Baoding in the BTH region; Shanghai, Suzhou, Wuxi, Nanjing, Hangzhou, Ningbo in the YRD region; Guangzhou, Shenzhen, Dongguan, Foshan in the PYD region, respectively. Additionally, monthly emission profiles are established in order to further identify

  5. Exotic hadrons from heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Cho, Sungtae; Hyodo, Tetsuo; Jido, Daisuke; Ko, Che Ming; Lee, Su Houng; Maeda, Saori; Miyahara, Kenta; Morita, Kenji; Nielsen, Marina; Ohnishi, Akira; Sekihara, Takayasu; Song, Taesoo; Yasui, Shigehiro; Yazaki, Koichi

    2017-07-01

    High energy heavy ion collisions are excellent ways for producing heavy hadrons and composite particles, including the light (anti)nuclei. With upgraded detectors at the Relativistic Heavy Ion Collider (RHIC) and the Large Hadron Collider (LHC), it has become possible to measure hadrons beyond their ground states. Therefore, heavy ion collisions provide a new method for studying exotic hadrons that are either molecular states made of various hadrons or compact system consisting of multiquarks. Because their structures are related to the fundamental properties of Quantum Chromodynamics (QCD), studying exotic hadrons is currently one of the most active areas of research in hadron physics. Experiments carried out at various accelerator facilities have indicated that some exotic hadrons may have already been produced. The present review is a summary of the current understanding of a selected set of exotic particle candidates that can be potentially measured in heavy ion collisions. It also includes discussions on the production of resonances, exotics and hadronic molecular states in these collisions based on the coalescence model and the statistical model. A more detailed discussion is given on the results from these models, leading to the conclusion that the yield of a hadron that is a compact multiquark state is typically an order of magnitude smaller than if it is an excited hadronic state with normal quark numbers or a loosely bound hadronic molecule. Attention is also given to some of the proposed heavy exotic hadrons that could be produced with sufficient abundance in heavy ion collisions because of the significant numbers of charm and bottom quarks that are produced at RHIC and even larger numbers at LHC, making it possible to study them in these experiments. Further included in the discussion are the general formalism for the coalescence model that involves resonance particles and its implication on the present estimated yield for resonance production. Finally

  6. Pions from and about heavy ions

    SciTech Connect

    Rasmussen, J.O.

    1982-09-01

    A review is presented of the possibilities of pion production with heavy ion reactions. Major headings include: pion thermometry; hills and valleys in pion spectra; pionic orbits of nuclear size; pion confinement in the fireball; anomalons; and Schroedinger equation solutions for pionic atoms. 47 references, 9 figures. (GHT)

  7. Green's function methods in heavy ion shielding

    NASA Technical Reports Server (NTRS)

    Wilson, John W.; Costen, Robert C.; Shinn, Judy L.; Badavi, Francis F.

    1993-01-01

    An analytic solution to the heavy ion transport in terms of Green's function is used to generate a highly efficient computer code for space applications. The efficiency of the computer code is accomplished by a nonperturbative technique extending Green's function over the solution domain. The computer code can also be applied to accelerator boundary conditions to allow code validation in laboratory experiments.

  8. Super high energy heavy ion collisions

    SciTech Connect

    Geist, W.M.

    1987-12-01

    Basic theoretical ideas on a phase transition to a plasma of free quarks and gluons in heavy ion collisions are outlined. First results from experiments with oxygen beams at 14.5 GeV/c/N (BNL), 60 and 200 GeV/c/N (CERN) are discussed. 30 refs., 9 figs.

  9. Relativistic Hydrodynamics for Heavy-Ion Collisions

    ERIC Educational Resources Information Center

    Ollitrault, Jean-Yves

    2008-01-01

    Relativistic hydrodynamics is essential to our current understanding of nucleus-nucleus collisions at ultrarelativistic energies (current experiments at the Relativistic Heavy Ion Collider, forthcoming experiments at the CERN Large Hadron Collider). This is an introduction to relativistic hydrodynamics for graduate students. It includes a detailed…

  10. Resonant structures in heavy-ion reactions

    SciTech Connect

    Sanders, S.J.; Henning, W.; Ernst, H.; Geesaman, D.F.; Jachcinski, C.; Kovar, D.G.; Paul, M.; Schiffer, J.P.

    1980-01-01

    An investigation of heavy-ion resonance structures using the /sup 24/Mg(/sup 16/O, /sup 12/C)/sup 28/Si reaction is presented. The data are analyzed in the context of Breit-Wigner resonances added to a direct-reaction background.

  11. Pion probes of heavy ion collision dynamics

    SciTech Connect

    Rasmussen, J.O.

    1985-03-01

    Pion interferometry data (2-pion correlation) are examined for information on size and lifetime of the pion-emitting matter. The temperatures inferred from pion, proton and kaon spectra are considered. An explanation consistent with the above size and temperature data is proposed. New theoretical Monte Carlo results on spectator effects on heavy-ion pion spectra are presented. 23 refs., 9 figs.

  12. Relativistic Hydrodynamics for Heavy-Ion Collisions

    ERIC Educational Resources Information Center

    Ollitrault, Jean-Yves

    2008-01-01

    Relativistic hydrodynamics is essential to our current understanding of nucleus-nucleus collisions at ultrarelativistic energies (current experiments at the Relativistic Heavy Ion Collider, forthcoming experiments at the CERN Large Hadron Collider). This is an introduction to relativistic hydrodynamics for graduate students. It includes a detailed…

  13. RELATIVISTIC HEAVY ION PHYSICS: A THEORETICAL OVERVIEW.

    SciTech Connect

    KHARZEEV,D.

    2004-03-28

    This is a mini-review of recent theoretical work in the field of relativistic heavy ion physics. The following topics are discussed initial conditions and the Color Glass Condensate; approach to thermalization and the hydrodynamic evolution; hard probes and the properties of the Quark-Gluon Plasma. Some of the unsolved problems and potentially promising directions for future research are listed as well.

  14. Heavy Ion Fragmentation Experiments at the Bevatron

    NASA Technical Reports Server (NTRS)

    Heckman, H. H.

    1975-01-01

    Fragmentation processes of heavy nuclei in matter using the heavy-ion capability of the Bevatron were studied. The purpose was to obtain the single particle inclusive spectra of secondary nuclei produced at 0 deg by the fragmentation of heavy ion beam projectiles. The process being examined is B+T yields F + anything, where B is the beam nucleus, T is the target nucleus, and F is the detected fragment. The fragments F are isotopically identified by experimental procedures involving magnetic analysis, energy loss and time-of-flight measurements. Attempts were also made to: (1) measure the total and partial production cross section for all isotopes, (2) test the applicability of high-energy multi-particle interaction theory to nuclear fragmentation, (3) apply the cross-section data and fragmentation probabilities to cosmic ray transport theory, and (4) search for systematic behavior of fragment production as a means to improve existing semi-empirical theories of cross sections.

  15. The future of heavy ion radiotherapy

    SciTech Connect

    Jäkel, Oliver; Karger, Christian P.; Debus, Jürgen

    2008-12-15

    Currently, there is an increasing interest in heavy ion radiotherapy (RT) and a number of new facilities are being installed in Europe and Japan. This development is accompanied by intensive technical, physical, and clinical research. The authors identify six research fields where progress is likely and propose a thesis on the expected achievements for each of the fields: (1) Synchrotrons with active energy variation and three-dimensional beam scanning will be the standard in ion beam RT. (2) Common standards for precise measurement, prescription, and reporting of dose will be available. (3) Intensity-modulated particle therapy will be state-of-the-art. (4) Time-adaptive treatments of moving targets will be feasible. (5) Therapeutic effectiveness of heavy ions will be known for the most important indications while cost effectiveness will remain to be shown. (6) The potential of high-linear energy transfer radiation will be known. The rationale for each of these theses is described.

  16. The future of heavy ion radiotherapy.

    PubMed

    Jäkel, Oliver; Karger, Christian P; Debus, Jürgen

    2008-12-01

    Currently, there is an increasing interest in heavy ion radiotherapy (RT) and a number of new facilities are being installed in Europe and Japan. This development is accompanied by intensive technical, physical, and clinical research. The authors identify six research fields where progress is likely and propose a thesis on the expected achievements for each of the fields: (1) Synchrotrons with active energy variation and three-dimensional beam scanning will be the standard in ion beam RT. (2) Common standards for precise measurement, prescription, and reporting of dose will be available. (3) Intensity-modulated particle therapy will be state-of-the-art. (4) Time-adaptive treatments of moving targets will be feasible. (5) Therapeutic effectiveness of heavy ions will be known for the most important indications while cost effectiveness will remain to be shown. (6) The potential of high-linear energy transfer radiation will be known. The rationale for each of these theses is described.

  17. High-energy accelerator for beams of heavy ions

    DOEpatents

    Martin, Ronald L.; Arnold, Richard C.

    1978-01-01

    An apparatus for accelerating heavy ions to high energies and directing the accelerated ions at a target comprises a source of singly ionized heavy ions of an element or compound of greater than 100 atomic mass units, means for accelerating the heavy ions, a storage ring for accumulating the accelerated heavy ions and switching means for switching the heavy ions from the storage ring to strike a target substantially simultaneously from a plurality of directions. In a particular embodiment the heavy ion that is accelerated is singly ionized hydrogen iodide. After acceleration, if the beam is of molecular ions, the ions are dissociated to leave an accelerated singly ionized atomic ion in a beam. Extraction of the beam may be accomplished by stripping all the electrons from the atomic ion to switch the beam from the storage ring by bending it in magnetic field of the storage ring.

  18. Nonresonant interaction of heavy ions with electromagnetic ion cyclotron waves

    NASA Technical Reports Server (NTRS)

    Berchem, J.; Gendrin, R.

    1985-01-01

    The motion of a heavy ion in the presence of an intense ultralow-frequency electromagnetic wave propagating along the dc magnetic field is analyzed. Starting from the basic equations of motion and from their associated two invariants, the heavy ion velocity-space trajectories are drawn. It is shown that after a certain time, particles whose initial phase angles are randomly distributed tend to bunch together, provided that the wave intensity b-sub-1 is sufficiently large. The importance of these results for the interpretation of the recently observed acceleration of singly charged He ions in conjunction with the occurrence of large-amplitude ion cyclotron waves in the equatorial magnetosphere is discussed.

  19. Medical heavy ion accelerator proposals

    NASA Astrophysics Data System (ADS)

    Gough, R. A.

    1985-05-01

    For several decades, accelerators designed primarily for research in nuclear and high energy physics have been adapted for biomedical research including radiotherapeutic treatment of human diseases such as pituitary disorders, cancer, and more recently, arteriovascular malformations. The particles used in these treatments include pions, protons and heavier ions such as carbon, neon, silicon and argon. Maximum beam energies must be available to penetrate into an equivalent of about 30 cm of water, requiring treatment beams of 250 to 1000 MeV/nucleon. Intensities must be adequate to complete a 100 rad treatment fraction in about 1 minute. The favored technical approach in these proposals utilizes a conventional, strong-focusing synchrotron capable of fast switching between ions and energies, and servicing multiple treatment rooms. Specialized techniques for shaping the dose to conform to irregularly-shaped target volumes, while simultaneously sparing surrounding, healthy tissue and critical structures, are employed in each treatment room, together with the sophisticated dosimetry necessary for verification, monitoring, and patient safety.

  20. Review of the heavy ion physics sessions

    SciTech Connect

    Jacak, B.V.

    1991-01-01

    The parallel sessions on Heavy Ion Physics covered several areas of recent progress in characterizing the nuclear equation of state and the search for deconfined quark matter. Studies of systems from 1 to several hundred GeV/nucleon have been made in order to map the behavior of nuclear matter over a wide range of temperatures and pressures. We have also considered results from proton-nucleus reactions in the heavy ion physics discussions. This should help untangle nuclear effects'' due to the presence of relatively undisturbed nuclear matter from observables arising in the hot, dense part of the system. Even though heavy ion physics covers a large range of bombarding energies, the same two basic questions must be answered. The first problem is to characterize the system that has been produced. We need to determine the energy density, lifetime, temperature and baryon density reached in the collision before expansion and particle production. Then we may address the second issue and look for evidence of new physics. At this meeting, we heard new results from experiments, and theoretical analyses which strive to explain all available data, including those from proton-nucleus collisions. We explored heavy quark production, which may indicate quark matter through color screening of c{bar c} pairs. We heard new results in strangeness production, which has been predicted to be enhanced if quark matter is formed. There were also discussions of jets and minijets, which may probe the hot, dense matter existing early in the collision.

  1. Comparison of Single Event Transients Generated by Short Pulsed X-Rays, Lasers and Heavy Ions

    SciTech Connect

    Cardoza, David; LaLumondiere, Stephen D.; Tockstein, Michael A.; Brewe, Dale L.; Wells, Nathan P.; Koga, Rokutaro; Gaab, K. M.; Lotshaw, William T.; Moss, Steven C.

    2014-12-01

    We report an experimental study of the transients generated by pulsed x-rays, heavy ions, and different laser wavelengths in a Si p-i-n photodiode. We compare the charge collected by all of the excitation methods to determine the equivalent LET for pulsed x-rays relative to heavy ions. Our comparisons show that pulsed x-rays from synchrotron sources can generate a large range of equivalent LET and generate transients similar to those excited by laser pulses and heavy ion strikes. We also look at how the pulse width of the transients changes for the different excitation methods. We show that the charge collected with pulsed x-rays is greater than expected as the x-ray photon energy increases. Combined with their capability of focusing to small spot sizes and of penetrating metallization, pulsed x-rays are a promising new tool for high resolution screening of SEE susceptibility

  2. Science and art in heavy-ion collisions

    SciTech Connect

    Weiss, M.S.

    1982-08-09

    One of the more intriguing phenomena discovered in heavy-ion physics is the seeming appearance of high energy structure in the excitation spectra of inelastically scattered heavy ions. For reasons illustrated, these may well be a phenomena unique to heavy ions and their explanation perhaps unique to TDHF.

  3. Open Heavy Flavor Measurements in Heavy Ion Collisions with CMS

    NASA Astrophysics Data System (ADS)

    Sun, Jian

    2016-12-01

    The measurement of heavy flavor production is a powerful tool to study the properties of the high-density QCD medium created in heavy-ion collisions as heavy quarks are sensitive to the transport properties of the medium and may interact with the matter differently than light quarks. Heavy flavor jets, non-prompt J / ψ (J / ψ from B-hadron decay) and fully reconstructed B mesons have been studied in PbPb collisions at 2.76 TeV and pPb collisions at 5.02 TeV with CMS. Recently, the nuclear modification factor of prompt D0 mesons has been measured in PbPb collisions at 2.76 TeV with CMS as a function of both transverse momentum and collision centrality. These studies show that prompt D0 production is suppressed in semi-central to central PbPb collisions and the suppression is smaller at high pT. A comparison with the RAA of charged particle and non-prompt J / ψ hints a hierarchy of suppression as a function of flavor.

  4. Fast prototyping of high-aspect ratio, high-resolution x-ray masks by gas-assisted focused ion beam

    NASA Technical Reports Server (NTRS)

    Hartley, F.; Malek, C.; Neogi, J.

    2001-01-01

    The capacity of chemically-assisted focused ion beam (fib) etching systems to undertake direct and highly anisotropic erosion of thin and thick gold (or other high atomic number [Z])coatings on x-ray mask membranes/substrates provides new levels of precision, flexibility, simplification and rapidity in the manufacture of mask absorber patterns, allowing the fast prototyping of high aspect ratio, high-resolution masks for deep x-ray lithography.

  5. Fast prototyping of high-aspect ratio, high-resolution x-ray masks by gas-assisted focused ion beam

    NASA Technical Reports Server (NTRS)

    Hartley, F.; Malek, C.; Neogi, J.

    2001-01-01

    The capacity of chemically-assisted focused ion beam (fib) etching systems to undertake direct and highly anisotropic erosion of thin and thick gold (or other high atomic number [Z])coatings on x-ray mask membranes/substrates provides new levels of precision, flexibility, simplification and rapidity in the manufacture of mask absorber patterns, allowing the fast prototyping of high aspect ratio, high-resolution masks for deep x-ray lithography.

  6. Effects of heavy ions on bacteria.

    PubMed

    Atlan, H

    1973-01-01

    Genetically well-known bacteria have been used to study efficiencies of heavy ions for mutation induction. For space experiments a technique of correlation of tracks of particles (in emulsion stacked on and between Petri dishes) with individual mutations, has been designed and checked in balloon flights. No clear cut results could be obtained without previous identification of genetic markers sensitive to irradiation by heavy ions. Accelerator experiments were performed at the Berkeley HILAC for systematic study. The results obtained on a strain of E. coli K12F- requiring threonine, leucine and arginine showed that the cell inactivation kinetics for gamma rays, helium, carbon and oxygen ions were almost identical (LD90 approaches 22krads) while argon was less effective (LD90 approaches 40 krads). Heavy ions up to oxygen were either equally or less efficient than gamma rays for induction of reverse mutations. Discrepancies between these findings and previous data on bacteria, yeast and Neurospora systems are discussed on the basis of radiosensitivity, ploidy, deletions, forward and reverse mutations.

  7. Ultra-Relativistic Heavy Ion Nuclear Physics

    SciTech Connect

    Braithwaite, W. J.

    1995-05-31

    This report describes an on-going research initiative for the University of Arkansas at Little Rock (UALR): investigating the physics of ultra-relativistic heavy ions, i.e. collisions between massive nuclei which have been accelerated to kinetic energies so large that the rest mass of the ions is a negligible fraction of their total mass-energy. This progress report is being submitted in conjunction with a 3-year grant-renewal proposal, containing additional materials. Three main categories drive the UALRGultra-relativistic heavy ion research. (1) investigations of multi-particle Hanbury-Brown-Twiss (HBT) correlations in the CERN and RHIC energy domains strongly influence the URHI experimental effort, (2) participation in the NA49 Experiment to study 33 TeV (160 GeV/nucleon) Pb on Pb collisions using the SPS facili& at CERN, and (3) participation in the STAR collaboration which is developing a major detector for use with the STAR Experiment at the Relativistic Heavy Ion Collider (RHIC), being built at BNL.

  8. Medium energy heavy ion operations at RHIC

    SciTech Connect

    Drees, K.A.; Ahrens, L.; Bai, M.; Beebe-Wang, J.; Blackler, I.M.C.; Blaskiewicz, M.; Brown, K.A.; Brennan, M.; Bruno, D.; Butler, J.; Carlson, C.; Connolly, R.; D'Ottavio, T.; Fischer, W.; Fu, W.; Gassner, D.; Harvey, M.; Hayes, T.; Huang, H.; Hulsart, R.; Ingrassia, P.; Kling, N.; Lafky, M.; Laster, J.; Lee, R.C.; Litvinenko, V.; Luo, Y.; MacKay, W.W.; Marr, G.; Mapes. M.; Marusic, A.; Mernick, K.; Michnoff, R.; Minty, M.; Montag, C.; Morris, J.; Naylor, C.; Nemesure, S.; Pilat, F.; Ptitsyn, V.; Robert-Demolaize, G.; Roser, T.; Sampson, P.; Satogata, T.; Schoefer, V.; Schultheiss, C.; Severino, F.; Shrey, T.; Smith, K.S.; Tepikian, S.; Thieberger, P.; Trbojevic, D.; Tsoupas, N.; Tuozzolo, J.; van Kuik, B.; Wilinski, M.; Zaltsman, A.; Zeno, K.; Zhang, S.Y.

    2011-03-28

    As part of the search for a phase transition or critical point on the QCD phase diagram, an energy scan including 5 different energy settings was performed during the 2010 RHIC heavy ion run. While the top beam energy for heavy ions is at 100 GeV/n and the lowest achieved energy setpoint was significantly below RHICs injection energy of approximately 10 GeV/n, we also provided beams for data taking in a medium energy range above injection energy and below top beam energy. This paper reviews RHIC experience and challenges for RHIC medium energy operations that produced full experimental data sets at beam energies of 31.2 GeV/n and 19.5 GeV/n. The medium energy AuAu run covered two beam energies, both above the RHIC injection energy of 9.8 GeV but well below the standard store energy of 100 GeV (see table 1). The low energy and full energy runs with heavy ions in FY10 are summarized in [1] and [2]. Stochastic Cooling ([3]) was only used for 100 GeV beams and not used in the medium energy run. The efficiency of the transition from 100 GeV operation to 31.2 GeV and then to 19.5 GeV was remarkable. Setup took 32 h and 19 h respectively for the two energy settings. The time in store, defined to be the percentage of time RHIC provides beams in physics conditions versus calendar time, was approximately 52% for the entire FY10 heavy ion run. In both medium energy runs it was well above this average, 68% for 31.5 GeV and 82% for 19.5 GeV. For both energies RHIC was filled with 111 bunches with 1.2 10{sup 9} and 1.3 10{sup 9} ions per bunch respectively.

  9. Modulation of Heavy Rainfall in the Middle East and North Africa by Madden-Julian Oscillation Using High Resolution Atmospheric General Circulation Model

    NASA Astrophysics Data System (ADS)

    Deng, L.; Stenchikov, G. L.; McCabe, M. F.; Bangalath, H. K.

    2014-12-01

    Recently, the modulation of subtropical rainfall by the dominant tropical intraseasonal signal of the Madden-Julian Oscillation (MJO), has been explored through the discussion of the MJO-convection-induced Kelvin and Rossby wave related teleconnection patterns. Our study focuses on characterizing the modulation of heavy rainfall in the Middle East and North Africa (MENA) region by the MJO, using the Geophysical Fluid Dynamics Laboratory (GFDL) global High Resolution Atmospheric Model (HIRAM) simulations (25-km; 1979-2012) and a combination of available atmospheric products from satellite, in-situ and reanalysis data. The observed Hadley Centre Global Sea Ice and Sea Surface Temperature (HadISST) and the simulated SST from GFDL's global coupled carbon-climate Earth System Models (ESM2M) are employed in HIRAM to investigate the sensitivity of the simulated heavy rainfall and MJO to SST. The future trend of the extreme rainfalls and their links to the MJO response to climate change are examined using HIRAM simulations of 2012-2050 with the RCP4.5 and RCP 8.5 scenarios to advance the possibility of characterization and forecasting of future extreme rainfall events in the MENA region.

  10. High Current Ion Sources and Injectors for Heavy Ion Fusion

    SciTech Connect

    Kwan, Joe W.

    2005-02-15

    Heavy ion beam driven inertial fusion requires short ion beam pulses with high current and high brightness. Depending on the beam current and the number of beams in the driver system, the injector can use a large diameter surface ionization source or merge an array of small beamlets from a plasma source. In this paper, we review the scaling laws that govern the injector design and the various ion source options including the contact ionizer, the aluminosilicate source, the multicusp plasma source, and the MEVVA source.

  11. Mutagenic effects of heavy ions in bacteria

    NASA Astrophysics Data System (ADS)

    Horneck, G.; Krasavin, E. A.; Kozubek, S.

    1994-10-01

    Various mutagenic effects by heavy ions were studied in bacteria, irradiated at accelerators in Dubna, Prague, Berkeley or Darmstadt. Endpoints investigated are histidine reversion (B. subtilis, S. typhimurium), azide resistance (B. subtilis), mutation in the lactose operon (E. coli), SOS chromotest (E. coli) and λ-prophage induction (E. coli). It was found that the cross sections of the different endpoints show a similar dependence on energy. For light ions (Z <= 4) the cross section decreases with increasing energy. For ions of Z = 10, it is nearly independent of energy. For heavier ions (Z >= 26) it increases with energy up to a maximum or saturation. The increment becomes steeper with increasing Z. This dependence on energy suggests a ``mutagenic belt'' inside the track that is restricted to an area where the density of departed energy is low enough not to kill the cell, but high enough to induce mutations.

  12. Heavy Ions In Space (HIIS) experiment

    NASA Technical Reports Server (NTRS)

    Adams, James H., Jr.; Beahm, Lorraine P.; Tylka, Allan J.

    1992-01-01

    The Heavy Ions In Space (HIIS) experiment has two primary objectives: (1) to measure the elemental composition of ultraheavy Galactic cosmic rays, beginning in the tin-barium region of the periodic table; and (2) to study heavy ions which arrive at LDEF below the geomagnetic cutoff, either because they are not fully stripped of electrons or because their source is within the magnetosphere. Both have practical as well as astrophysical consequences. The HIIS experiment used eight thick stacks of plastic track detectors mounted in two trays on the space facing end of LDEF. Since the last LDEF symposium, the statistics were increased of the observations and have extended the analysis to a second stack and to detector sheets near the top of a stack. New results are reported on the detector resolution and on the observations of both stopping and relativistic particles.

  13. Chiral Magnetic Effect in Heavy Ion Collisions

    SciTech Connect

    Liao, Jinfeng

    2016-12-01

    The Chiral Magnetic Effect (CME) is a remarkable phenomenon that stems from highly nontrivial interplay of QCD chiral symmetry, axial anomaly, and gluonic topology. We show it is of fundamental importance to search for the CME in experiments. The heavy ion collisions provide a unique environment where a hot chiral-symmetric quark-gluon plasma is created, gluonic topological fluctuations generate chirality imbalance, and very strong magnetic fields |Β|~m2π are present during the early stage of such collisions. Significant efforts have been made to look for CME signals in heavy ion collision experiments. Lastly, in this contribution we give a brief overview on the status of such efforts.

  14. Chiral Magnetic Effect in Heavy Ion Collisions

    DOE PAGES

    Liao, Jinfeng

    2016-12-01

    The Chiral Magnetic Effect (CME) is a remarkable phenomenon that stems from highly nontrivial interplay of QCD chiral symmetry, axial anomaly, and gluonic topology. We show it is of fundamental importance to search for the CME in experiments. The heavy ion collisions provide a unique environment where a hot chiral-symmetric quark-gluon plasma is created, gluonic topological fluctuations generate chirality imbalance, and very strong magnetic fields |Β→|~m2π are present during the early stage of such collisions. Significant efforts have been made to look for CME signals in heavy ion collision experiments. Lastly, in this contribution we give a brief overview onmore » the status of such efforts.« less

  15. Dynamical processes in heavy ion reactions

    SciTech Connect

    Blann, M.; Remington, B.A.

    1988-07-25

    In this report I review the physical assumptions of the Boltzmann Master Equation (BME). Comparisons of the model with experimental neutron spectra gated on evaporation residues for a range of incident projectile energies and masses are presented; next, I compare n spectra gated on projectile-like fragments, followed by comparisons with ungated, inclusive proton spectra. I will then consider secondary effects from the nucleon-nucleon processes involved in the heavy ion relaxation processes, specifically the high energy ..gamma..-rays which have been observed at energies up to 140 MeV in collisions of heavy ions of 20/endash/84 MeV/..mu... Another secondary effect, subthreshold pion production, was covered in the XVII School and will not be repeated. 39 refs., 16 figs.

  16. Viscous photons in relativistic heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Dion, Maxime; Paquet, Jean-François; Schenke, Björn; Young, Clint; Jeon, Sangyong; Gale, Charles

    2011-12-01

    Theoretical studies of the production of real thermal photons in relativistic heavy ion collisions at the Relativistic Heavy Ion Collider (RHIC) are performed. The space-time evolution of the colliding system is modelled using music, a 3+1D relativistic hydrodynamic simulation, using both its ideal and viscous versions. The inclusive spectrum and its azimuthal angular anisotropy are studied separately, and the relative contributions of the different photon sources are highlighted. It is shown that the photon v2 coefficient is especially sensitive to the details of the microscopic dynamics like the equation of state, the ratio of shear viscosity over entropy density, η/s, and to the morphology of the initial state.

  17. Faster Heavy Ion Transport for HZETRN

    NASA Technical Reports Server (NTRS)

    Slaba, Tony C.

    2013-01-01

    The deterministic particle transport code HZETRN was developed to enable fast and accurate space radiation transport through materials. As more complex transport solutions are implemented for neutrons, light ions (Z < 2), mesons, and leptons, it is important to maintain overall computational efficiency. In this work, the heavy ion (Z > 2) transport algorithm in HZETRN is reviewed, and a simple modification is shown to provide an approximate 5x decrease in execution time for galactic cosmic ray transport. Convergence tests and other comparisons are carried out to verify that numerical accuracy is maintained in the new algorithm.

  18. The Relativistic Heavy Ion Collider at Brookhaven

    SciTech Connect

    Hahn, H.

    1988-01-01

    The conceptual design of a Relativistic Heavy Ion Collider (RACK) to be constructed in the existing 3.8 km tunnel at Brookhaven has been developed. The collider has been designed to provide collisions of gold ions at six intersection points with a luminosity of about 5 /times/ 10/sup 26/cm/sup /minus/2/sec/sup /minus/1/ at an energy of 100 GeV/u in each beam. Collisions with different ion species, including protons, will be possible. The collider consists of two interlaced, but otherwise separate, superconducting magnet rings. The 9.7 m long dipoles will operate at 3.5 T. Their 8 cm aperture was determined by the dimensions of gold ion beams taking into account diffusion due to intrabeam scattering. Heavy ion beams will be available from the Tandem Van de Graaff/Booster/AGS complex. The salient design features and the reasons for major design choices of the proposed machine are discussed in this paper. 24 refs., 7 figs., 2 tabs.

  19. Chromosomal instability induced by heavy ion irradiation

    NASA Technical Reports Server (NTRS)

    Limoli, C. L.; Ponnaiya, B.; Corcoran, J. J.; Giedzinski, E.; Morgan, W. F.

    2000-01-01

    PURPOSE: To establish the dose-response relationship for the induction of chromosomal instability in GM10115 cells exposed to high-energy iron ions (1 GeV/nucleon, mean LET 146 keV/microm) and gold ions (11 GeV/nucleon, mean LET 1450 keV/microm). Past work has established that sparsely ionizing X-rays can induce a long-lived destabilization of chromosomes in a dose-dependent manner at an incidence of approximately 3% per gray. The present investigation assesses the capacity of High-Z and High-energy (HZE) particles to elicit this same endpoint. MATERIALS AND METHODS: Clonal populations derived from single progenitor cells surviving heavy-ion irradiation were analyzed cytogenetically to identify those clones showing a persistent destablization of chromosomes. RESULTS: Dose-response data, with a particular emphasis at low dose (< 1.0 Gy), indicate a frequency of approximately 4% per gray for the induction of chromosomal instability in clones derived from single progenitor cells surviving exposure to iron ions. The induction of chromosomal instability by gold ions was, however, less responsive to applied dose, as the observed incidence of this phenotype varied from 0 to 10% over 1-8 Gy. Both iron and gold ions gave dose-dependent increases in the yield of chromosomal aberrations (both chromosome- and chromatid-type) measured at the first mitosis following irradiation, as well as shoulderless survival curves having D0=0.87 and 1.1 Gy respectively. CONCLUSIONS: Based on the present dose-response data, the relative biological effectiveness of iron ions is 1.3 for the induction of chromosomal instability, and this indicates that heavy ions are only slightly more efficient than X-rays at eliciting this delayed phenotype.

  20. Chromosomal instability induced by heavy ion irradiation

    NASA Technical Reports Server (NTRS)

    Limoli, C. L.; Ponnaiya, B.; Corcoran, J. J.; Giedzinski, E.; Morgan, W. F.

    2000-01-01

    PURPOSE: To establish the dose-response relationship for the induction of chromosomal instability in GM10115 cells exposed to high-energy iron ions (1 GeV/nucleon, mean LET 146 keV/microm) and gold ions (11 GeV/nucleon, mean LET 1450 keV/microm). Past work has established that sparsely ionizing X-rays can induce a long-lived destabilization of chromosomes in a dose-dependent manner at an incidence of approximately 3% per gray. The present investigation assesses the capacity of High-Z and High-energy (HZE) particles to elicit this same endpoint. MATERIALS AND METHODS: Clonal populations derived from single progenitor cells surviving heavy-ion irradiation were analyzed cytogenetically to identify those clones showing a persistent destablization of chromosomes. RESULTS: Dose-response data, with a particular emphasis at low dose (< 1.0 Gy), indicate a frequency of approximately 4% per gray for the induction of chromosomal instability in clones derived from single progenitor cells surviving exposure to iron ions. The induction of chromosomal instability by gold ions was, however, less responsive to applied dose, as the observed incidence of this phenotype varied from 0 to 10% over 1-8 Gy. Both iron and gold ions gave dose-dependent increases in the yield of chromosomal aberrations (both chromosome- and chromatid-type) measured at the first mitosis following irradiation, as well as shoulderless survival curves having D0=0.87 and 1.1 Gy respectively. CONCLUSIONS: Based on the present dose-response data, the relative biological effectiveness of iron ions is 1.3 for the induction of chromosomal instability, and this indicates that heavy ions are only slightly more efficient than X-rays at eliciting this delayed phenotype.

  1. Heavy ion fragmentation experiments at the bevatron

    NASA Technical Reports Server (NTRS)

    Heckman, H. H.

    1976-01-01

    Collaborative research efforts to study the fragmentation processes of heavy nuclei in matter using heavy ion beams of the Bevatron/Bevalac are described. The goal of the program is to obtain the single particle inclusive spectra of secondary nuclei produced at 0 deg by the fragmentation of heavy ion beam projectiles. The process being examined is B+T yields F + anything, where B is the beam nucleus, T is the target nucleus, and F is the detected fragment. The fragments F are isotopically identified by experimental procedures involving magnetic analysis, energy loss and time-of-flight measurements. Effects were also made to: (a) study processes of heavy nuclei in matter, (b) measure the total and partial production cross section for all isotopes, (c) test the applicability of high energy multiparticle interaction theory to nuclear fragmentation, (d) apply the cross section data and fragmentation probabilities to cosmic ray transport theory, and (e) search for systematic behavior of fragment production as a means to improve existing semi-empirical theories of cross-sections.

  2. Heavy Ion Fusion Systems Assessment study

    SciTech Connect

    Dudziak, D.J.; Herrmannsfeldt, W.B.

    1986-07-01

    The Heavy Ion Fusion Systems Assessment (HIFSA) study was conducted with the specific objective of evaluating the prospects of using induction linac drivers to generate economical electrical power from inertial confinement fusion. The study used algorithmic models of representative components of a fusion system to identify favored areas in the multidimensional parameter space. The resulting cost-of-electricity (COE) projections are comparable to those from other (magnetic) fusion scenarios, at a plant size of 100 MWe.

  3. Femtoscopy in Relativistic Heavy Ion Collisions

    SciTech Connect

    Lisa, M; Pratt, S; Soltz, R A; Wiedemann, U

    2005-07-29

    Analyses of two-particle correlations have provided the chief means for determining spatio-temporal characteristics of relativistic heavy ion collisions. We discuss the theoretical formalism behind these studies and the experimental methods used in carrying them out. Recent results from RHIC are put into context in a systematic review of correlation measurements performed over the past two decades. The current understanding of these results are discussed in terms of model comparisons and overall trends.

  4. Holifield Heavy Ion Research Facility: Users handbook

    SciTech Connect

    Auble, R.L.

    1987-01-01

    The primary objective of this handbook is to provide information for those who plan to carry out research programs at the Holifield Heavy Ion Research Facility (HHIRF) at Oak Ridge National Laboratory. The accelerator systems and experimental apparatus available are described. The mechanism for obtaining accelerator time and the responsibilities of those users who are granted accelerator time are described. The names and phone numbers of ORNL personnel to call for information about specific areas are given. (LEW)

  5. Heavy ion fusion 2 MV injector

    SciTech Connect

    Yu, S.; Eylon, S.; Henestroza, E.

    1995-04-01

    A heavy-ion-fusion driver-scale injector has been constructed and operated at Lawrence Berkeley Laboratory. The injector has produced 2.3 MV and 950 mA of K{sup +}, 15% above original design goals in energy and current. Normalized edge emittance of less than 1 {pi} mm-mr was measured over a broad range of parameters. The head-to-tail energy flatness is less than {+-} 0.2% over the 1 {micro}s pulse.

  6. Hyperons polarization in heavy-ion collisions

    NASA Astrophysics Data System (ADS)

    Baznat, Mircea; Gudima, Konstantin; Sorin, Alexander; Teryaev, Oleg

    2017-03-01

    We study the structure of vorticity and hydrodynamic helicity fields in peripheral heavy-ion collisions using the kinetic Quark-Gluon Strings Model. The angular momentum which is a source of P-odd observables is preserved within this model with a good accuracy. We observe the formation of specific toroidal structures of vorticity field. Their existence is mirrored in the polarization of hyperons of the percent order. The observed qualitative energy dependence of polarization was predicted earlier and is quantified now.

  7. Overview of US heavy ion fusion research

    SciTech Connect

    Logan, B.G.; Bieniosek, F.M.; Celata, C.M.; Henestroza, E.; Kwan,J.W.; Lee, E.P.; Leitner, M.; Roy, P.K.; Seidl, P.A.; Eylon, S.; Vay,J-L.; Waldron, W.L.; Yu, S.S.; Barnard, J.J.; Callahan, D.A.; Cohen,R.H.; Friedman, A.; Grote, D.P; Covo, Kireeff M.; Meier, W.R.; Molvik,A.W.; Lund, S.M.; Davidson, R.C.; Efthimion, P.C.; Gilson, E.P.; Grisham,L.R.; Kaganovich, I.D.; Qin, H.; Startsev, E.A.; Rose, D.V.; Welch, D.R.; Olson, C.L.; Kishek, R.A.; O'Shea, P.; Haber, I.; Prost, L.R.; Prost, L.

    2004-11-01

    Significant experimental and theoretical progress has been made in the U.S. heavy ion fusion program on high-current sources, injectors, transport, final focusing, chambers and targets for high energy density physics (HEDP) and inertial fusion energy (IFE) driven by induction linac accelerators. One focus of present research is the beam physics associated with quadrupole focusing of intense, space-charge dominated heavy-ion beams, including gas and electron cloud effects at high currents, and the study of long-distance-propagation effects such as emittance growth due to field errors in scaled experiments. A second area of emphasis in present research is the introduction of background plasma to neutralize the space charge of intense heavy ion beams and assist in focusing the beams to a small spot size. In the near future, research will continue in the above areas, and a new area of emphasis will be to explore the physics of neutralized beam compression and focusing to high intensities required to heat targets to high energy density conditions as well as for inertial fusion energy.

  8. Overview of US heavy ion fusion research

    SciTech Connect

    Logan, B.G.; Bieniosek, F.M.; Celata, C.M.; Henestroza, E.; Kwan,J.W.; Lee, E.P.; Leitner, M.; Roy, P.K.; Seidl, P.A.; Eylon, S.; Vay,J-L.; Waldron, W.L.; Yu, S.S.; Barnard, J.J.; Callahan, D.A.; Cohen,R.H.; Friedman, A.; Grote, D.P.; Kireeff Covo, M.; Meier, W.R.; Molvik,A.W.; Lund, S.M.; Davidson, R.C.; Efthimion, P.C.; Gilson, E.P.; Grisham,L.R.; Kaganovich, I.D.; Qin, H.; Startsev, E.A.; Rose, D.V.; Welch, D.R.; Olson, C.L.; Kishek, R.A.; O'Shea, P.; Haber, I.; Prost, L.R.

    2005-06-23

    Significant experimental and theoretical progress has been made in the U.S. heavy ion fusion program on high-current sources, injectors, transport, final focusing, chambers and targets for high energy density physics (HEDP) and inertial fusion energy (IFE) driven by induction linac accelerators. One focus of present research is the beam physics associated with quadrupole focusing of intense, space-charge dominated heavy-ion beams, including gas and electron cloud effects at high currents, and the study of long-distance-propagation effects such as emittance growth due to field errors in scaled experiments. A second area of emphasis in present research is the introduction of background plasma to neutralize the space charge of intense heavy ion beams and assist in focusing the beams to a small spot size. In the near future, research will continue in the above areas, and a new area of emphasis will be to explore the physics of neutralized beam compression and focusing to high intensities required to heat targets to high energy density conditions as well as for inertial fusion energy.

  9. Heavy ion driven LMF design concept. Revised

    SciTech Connect

    Lee, E.P.

    1995-07-01

    From 1988 to 1991, the US Department of Energy conducted a study of the requirements, designs and costs for a Laboratory Microfusion Facility (LMF). The primary purpose of the LMF would be testing of weapons physics and effects simulation using the output from microexplosions of inertial fusion targets. It does not need a high repetition rate, efficient driver system as required by an electrical generating plant; however there would be so many features in common that the design, construction and operation of an LMF would considerably advance the application of inertial confinement fusion to energy production. The DOE study concentrated particularly on the LMF driver, with design and component development undertaken at several national laboratories. Heavy Ions, although considered a possible LMF driver, did not receive attention until the final stages of this study since its program management was through the Office of Energy Research rather than Defense Programs. However, during preparation of the summary report for the study it was decided that an account of heavy ions was needed for a complete survey of the driver candidates. The conceptual heavy ion LMF driver design created for the DOE report did not receive the level of scrutiny of the other driver concepts and, unlike the others, no cost analysis by an independent contractor was performed.

  10. The heavy ion injection scheme for RHIC (Relativistic Heavy Ion Collider)

    SciTech Connect

    Rhoades-Brown, M.J.

    1989-01-01

    The Relativistic Heavy Ion Collider (RHIC) at Brookhaven has a multi-component injection system. The Collider requires very heavy ions such as /sub 79//sup 197/Au to be injected fully stripped of atomic electrons, at a kinetic energy of approximately 10 GeV/nucleon. However, the heavy ions are produced initially at a negative ion source and accelerated first in a 15 MV Tandem. These partially stripped ions have a kinetic energy of approximately 1 MeV/nucleon on leaving the Tandem. In order to achieve the injection requirements for RHIC, the partially stripped ions are accelerated in the Booster (currently under construction) and pass through a stripping foil on their way to the Alternating Gradient Synchrotron (AGS), where they are further accelerated before injection into RHIC. Recent theoretical calculations have shown quite convincingly that very heavy ions with 2 electrons in the filled K-shell may be accelerated with negligible loss in the AGS. 13 refs., 3 figs., 3 tabs.

  11. Suppression and Two-Particle Correlations of Heavy Mesons in Heavy-Ion Collisions

    NASA Astrophysics Data System (ADS)

    Cao, Shanshan; Qin, Guang-You; Bass, Steffen A.

    2016-12-01

    We study the medium modification of heavy quarks produced in heavy-ion collisions. The evolution of heavy quarks inside the QGP is described using a modified Langevin framework that simultaneously incorporates their collisional and radiative energy loss. Within this framework, we provide good descriptions of the heavy meson suppression and predictions for the two-particle correlation functions of heavy meson pairs.

  12. Genetic effects on heavy ions in drosophila

    NASA Technical Reports Server (NTRS)

    Kale, P. G.

    1986-01-01

    Drosophila sex-linked recessive lethal mutation test was used to study the dose response relation and relative biological effectiveness of heavy ions. The experiments were performed using the heavy ion beams at BEVALAC of Lawrence Berkeley Laboratory. These experiments were undertaken according to the proposed milestones and included Ne-20, A-40 and Fe-65 ions with respective energies of 600 MeV, 840 MeV and 850 MeV. At these energies several doses of these radiations ranging from 20 to 1280 R were used. Space radiation exposure to astronauts is supposed to be quite low and therefore very low dose experiments i.e., 20 R, were also performed for the three ions. The mutation response was measured in all germ cell types i.e., spermatozoa, spermatids, spermatocytes and spermatogonia of treated Drosophila males. A linear dose frequency relation was observed for most of the range except at high doses where the saturation effect was observed. Also, a very significant difference was observed among the sensitivity of the four germ cell stages where spermatozoa and spermatids were more sensitive. At the higher doses of this range, most of the spermatogonia and spermatocytes were killed. Although comparative and identical experiments with X-rays or neutrons have not been performed, the compassion of our data with the ones available in literature suggest that the heavy ions have a high rbe and that they are several times more effective than low LET X-rays. The rbe compared to neutrons however appears to be only slightly higher.

  13. High-resolution grazing-incidence grating spectrometer for temperature measurements of low-Z ions emitting in the 100–300 Å spectral band

    SciTech Connect

    Widmann, K. Beiersdorfer, P.; Magee, E. W.; Boyle, D. P.; Kaita, R.; Majeski, R.

    2014-11-15

    We have constructed a high-resolution grazing-incidence spectrometer designed for measuring the ion temperature of low-Z elements, such as Li{sup +} or Li{sup 2+}, which radiate near 199 Å and 135 Å, respectively. Based on measurements at the Livermore Electron Beam Ion Trap we have shown that the instrumental resolution is better than 48 mÅ at the 200 Å setting and better than 40 mÅ for the 135-Å range. Such a high spectral resolution corresponds to an instrumental limit for line-width based temperature measurements of about 45 eV for the 199 Å Li{sup +} and 65 eV for the 135 Å Li{sup 2+} lines. Recently obtained survey spectra from the Lithium Tokamak Experiment at the Princeton Plasma Physics Laboratory show the presence of these lithium emission lines and the expected core ion temperature of approximately 70 eV is sufficiently high to demonstrate the feasibility of utilizing our high-resolution spectrometer as an ion-temperature diagnostic.

  14. High-resolution grazing-incidence grating spectrometer for temperature measurements of low-Z ions emitting in the 100–300 Å spectral band

    SciTech Connect

    Widmann, K.; Beiersdorfer, P.; Magee, E. W.; Boyle, D. P.; Kaita, R.; Majeski, R.

    2014-11-01

    We have constructed a high-resolution grazing-incidence spectrometer designed for measuring the ion temperature of low-Z elements, such as Li+ or Li2 +, which radiate near 199 Å and 135 Å, respectively. Based on measurements at the Livermore Electron Beam Ion Trap we have shown that the instrumental resolution is better than 48 mÅ at the 200 Å setting and better than 40 mÅ for the 135-Å range. Such a high spectral resolution corresponds to an instrumental limit for line-width based temperature measurements of about 45 eV for the 199 Å Li+ and 65 eV for the 135 Å Li2 + lines. Recently obtained survey spectra from the Lithium Tokamak Experiment at the Princeton Plasma Physics Laboratory show the presence of these lithium emission lines and the expected core ion temperature of approximately 70 eV is sufficiently high to demonstrate the feasibility of utilizing our high-resolution spectrometer as an ion-temperature diagnostic.

  15. High-resolution storage-ring measurements of the dissociative recombination of H{sub 3}{sup +} using a supersonic expansion ion source

    SciTech Connect

    Kreckel, Holger; Crabtree, Kyle N.; Tom, Brian A.; Novotny, Oldrich; Lestinsky, Michael; Buhr, Henrik; Petrignani, Annemieke; Berg, Max H.; Bing, Dennis; Grieser, Manfred; Krantz, Claude; Mendes, Mario B.; Nordhorn, Christian; Repnow, Roland; Stuetzel, Julia; Wolf, Andreas; Thomas, Richard D.; McCall, Benjamin J.

    2010-10-15

    We have performed measurements of the dissociative electron recombination (DR) of H{sub 3}{sup +} at the ion storage ring TSR utilizing a supersonic expansion ion source. The ion source has been characterized by continuous wave cavity ring-down spectroscopy. We present high-resolution DR rate coefficients for different nuclear spin modifications of H{sub 3}{sup +} combined with precise fragment imaging studies of the internal excitation of the H{sub 3}{sup +} ions inside the storage ring. The measurements resolve changes in the energy dependence between the ortho-H{sub 3}{sup +} and para-H{sub 3}{sup +} rate coefficients at low center-of-mass collision energies. Analysis of the imaging data indicates that the stored H{sub 3}{sup +} ions may have higher rotational temperatures than previously assumed, most likely due to collisional heating during the extraction of the ions from the ion source. Simulations of the ion extraction shed light on possible origins of the heating process and how to avoid it in future experiments.

  16. High current injector for heavy ion fusion

    NASA Astrophysics Data System (ADS)

    Yu, S.; Eylon, S.; Chupp, W. W.

    1993-05-01

    A 2 MV, 800 mA, K(+) injector for heavy ion fusion studies is under construction. This new injector is a one-beam version of the proposed 4-beam ILSE injector. A new 36-module MARX is being built to achieve a 5 micro-s flat top. The high voltage generator is stiff (less than 5k Omega) to minimize effects of beam-induced transients. A large (approximately 7 in. diameter) curved hot alumina-silicate source emits a 1 micro-s long beam pulse through a gridless extraction electrode, and the ions are accelerated to 1 MV in a diode configuration. Acceleration to 2 MV takes place in a set of electrostatic quadrupole (ESQ) units, arranged to simultaneously focus and accelerate the ion beam. Heavy shields and other protection devices have been built in to minimize risks of high voltage breakdown. Beam aberration effects through the ESQ have been studied extensively with theory, simulations, and scaled experiments. The design, simulations, experiments, and engineering of the ESQ injector will be presented.

  17. Identifying Multiquark Hadrons from Heavy Ion Collisions

    SciTech Connect

    Cho, Sungtae; Furumoto, Takenori; Yazaki, Koichi; Hyodo, Tetsuo; Jido, Daisuke; Ohnishi, Akira; Ko, Che Ming; Lee, Su Houng; Nielsen, Marina; Sekihara, Takayasu; Yasui, Shigehiro

    2011-05-27

    Identifying hadronic molecular states and/or hadrons with multiquark components either with or without exotic quantum numbers is a long-standing challenge in hadronic physics. We suggest that studying the production of these hadrons in relativistic heavy ion collisions offers a promising resolution to this problem as yields of exotic hadrons are expected to be strongly affected by their structures. Using the coalescence model for hadron production, we find that, compared to the case of a nonexotic hadron with normal quark numbers, the yield of an exotic hadron is typically an order of magnitude smaller when it is a compact multiquark state and a factor of 2 or more larger when it is a loosely bound hadronic molecule. We further find that some of the newly proposed heavy exotic states could be produced and realistically measured in these experiments.

  18. Ion source for desportion and ionization in strong electrostatic field for MKh1320 high-resolution mass spectrometer

    SciTech Connect

    Golovatyi, V.G.; Shabel'nikov, V.P.; Shpakovskii, I.V.

    1986-06-01

    This paper describes an ion source for an MKh1320 mass spectrometer for field desorption studies. The ion current of the main component recorded by the collector of the mass spectrometer is 10/sup -12/ A and the resolution is ca 1000. Tri-p-bromotriphenylamine (stable aromatic cation radical) was studied to determine the resolution of the mass spectrometer in the field desorption mode. A field desorption mass spectrum of this material with the emitter at room temperature is shown. The field desorption ion source can be used with IE-26, IE-26M, and/or IEP-23 industrial ion sources.

  19. CERN achievements in relativistic heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Eugenio Bruno, Giuseppe

    2015-05-01

    Twenty years after a Letter of Intent by the GSI and LBL groups for the "Study of particle production and target fragmentation in central 20Ne on Pb reactions, at 12 GeV per nucleon energy of the CERN PS external beam" [1], based on the results found by the NA45/CERES, NA49, NA50, and WA97/NA57 experiments at the SPS, CERN announced compelling evidence for the formation of a new state of matter in heavyion collisions at CERN-SPS energies [2]. Some of the experiments were indeed the 2nd or 3rd generation successors of the apparatuses originally proposed by the GSI-LBL collaboration. Actually, the CERN ion program initiated at the SPS with the acceleration of oxygen ions at 60 and 200 GeV/nucleon only in 1986, and continued with sulphur ions at 200 GeV/nucleon up to 1993. The rest is history: lead-ion beams at 160 GeV/nucleon became available at the SPS in 1994; the LHC accelerated and collided lead beams at a center of mass energy per nucleon pair √sNN = 2.76 TeV in 2010. Heavy ion physics is definitely in the future program of CERN: ALICE will operate a major upgrade of its detectors during the second long shutdown of the LHC, in 2018-2019, and the associated physics program will span the third and fourth LHC runs, till late 2020s.

  20. Application of high resolution X-ray emission spectroscopy on the study of Cr ion adsorption by activated carbon.

    PubMed

    Espinoza-Quiñones, Fernando R; Módenes, Aparecido N; Câmera, Adriana S; Stutz, Guillermo; Tirao, German; Palácio, Soraya M; Kroumov, Alexander D; Oliveira, Ana P; Alflen, Vanessa L

    2010-12-01

    In this work granular activated carbon has been chosen as an absorbent in order to investigate the Cr(VI) reduced by adsorption experiments. Several batch chromium-sorption experiments were carried out using 0.25 g of granular activated carbon in 50 mL aqueous solution containing approximately 70 and 140 mg L(-1) of Cr(VI) and Cr(III), respectively. Cr-Kbeta fluorescence spectra of Cr adsorbed in a carbon matrix and Cr reference materials were measured using a high-resolution Johann-type spectrometer. Based on evidence from the Cr-Kb satellite lines, the Cr(VI) reduction process has actually happened during metal adsorption by the activated carbon. Copyright 2010 Elsevier Ltd. All rights reserved.

  1. Vorticity in heavy-ion collisions

    NASA Astrophysics Data System (ADS)

    Deng, Wei-Tian; Huang, Xu-Guang

    2016-06-01

    We study the event-by-event generation of flow vorticity in the BNL Relativistic Heavy Ion Collider Au +Au collisions and CERN Large Hadron Collider Pb +Pb collisions by using the hijing model. Different definitions of the vorticity field and velocity field are considered. A variety of properties of the vorticity are explored, including the impact parameter dependence, the collision energy dependence, the spatial distribution, the event-by-event fluctuation of the magnitude and azimuthal direction, and the time evolution. In addition, the spatial distribution of the flow helicity is also studied.

  2. Jet reconstruction in heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Cacciari, Matteo; Rojo, Juan; Salam, Gavin P.; Soyez, Gregory

    2011-01-01

    We examine the problem of jet reconstruction at heavy-ion colliders using jet-area-based background subtraction tools as provided by FastJet. We use Monte Carlo simulations with and without quenching to study the performance of several jet algorithms, including the option of filtering, under conditions corresponding to RHIC and LHC collisions. We find that most standard algorithms perform well, though the anti- k t and filtered Cambridge/Aachen algorithms have clear advantages in terms of the reconstructed p t offset and dispersion.

  3. Progress in understanding heavy-ion stopping

    NASA Astrophysics Data System (ADS)

    Sigmund, P.; Schinner, A.

    2016-09-01

    We report some highlights of our work with heavy-ion stopping in the energy range where Bethe stopping theory breaks down. Main tools are our binary stopping theory (PASS code), the reciprocity principle, and Paul's data base. Comparisons are made between PASS and three alternative theoretical schemes (CasP, HISTOP and SLPA). In addition to equilibrium stopping we discuss frozen-charge stopping, deviations from linear velocity dependence below the Bragg peak, application of the reciprocity principle in low-velocity stopping, modeling of equilibrium charges, and the significance of the so-called effective charge.

  4. Non abelian hydrodynamics and heavy ion collisions

    SciTech Connect

    Calzetta, E.

    2014-01-14

    The goal of the relativistic heavy ion collisions (RHIC) program is to create a state of matter where color degrees of freedom are deconfined. The dynamics of matter in this state, in spite of the complexities of quantum chromodynamics, is largely determined by the conservation laws of energy momentum and color currents. Therefore it is possible to describe its main features in hydrodynamic terms, the very short color neutralization time notwithstanding. In this lecture we shall give a simple derivation of the hydrodynamics of a color charged fluid, by generalizing the usual derivation of hydrodynamics from kinetic theory to the non abelian case.

  5. Nonrelativistic theory of heavy-ion collisions

    SciTech Connect

    Bertsch, G.

    1984-07-17

    A wide range of phenomena is observed in heavy-ion collisions, calling for a comprehensive theory based on fundamental principles of many-particle quantum mechanics. At low energies, the nuclear dynamics is controlled by the mean field, as we know from spectroscopic nuclear physics. We therefore expect the comprehensive theory of collisions to contain mean-field theory at low energies. The mean-field theory is the subject of the first lectures in this chapter. This theory can be studied quantum mechanically, in which form it is called TDHF (time-dependent Hartree-Fock), or classically, where the equation is called the Vlasov equation. 25 references, 14 figures.

  6. Economic aspects of heavy ion fusion

    SciTech Connect

    Herrmannsfeldt, W.B.

    1984-01-01

    The usual parameter space for examining scenarios for heavy ion fusion power plants has generally been based on large, slow cycling, reactor chambers which are only marginally different from chambers proposed for laser drivers. This paper will examine the economic implications of assuming that an inexpensive, low gain pellet is available and that a suitable high-repetition rate reactor has been devised. Interesting scenarios are found that generate economically feasible power from a system with a minimum net capacity of approx. 1 GWe compared to the larger approx. 4 GWe required in previous studies.

  7. Heavy ion recoil spectrometry of barium strontium titanate films

    NASA Astrophysics Data System (ADS)

    Stannard, W. B.; Johnston, P. N.; Walker, S. R.; Bubb, I. F.; Scott, J. F.; Cohen, D. D.; Dytlewski, N.; Martin, J. W.

    1995-05-01

    Thin films of barium strontium titanate have been analysed using heavy ion recoil spectrometry with 77 and 98 MeV 127I ions at the new heavy ion recoil facility at ANSTO, Lucas Heights. New calibration procedures have been developed for quantitative analysis. Energy spectra for each of the elements present reveal interdiffusion that was not previously known.

  8. Heavy Ion Radiation Effects Studies With Ion Photon Emission Microscopy

    SciTech Connect

    Branson, J. V.; Hattar, K.; Vizkelethy, G.; Powell, C. J.; Doyle, B. L.; Rossi, P.

    2011-06-01

    The development of a new radiation effects microscopy (REM) technique is crucial as emerging semiconductor technologies demonstrate smaller feature sizes and thicker back end of line (BEOL) layers. To penetrate these materials and still deposit sufficient energy into the device to induce single event effects, high energy heavy ions are required. Ion photon emission microscopy (IPEM) is a technique that utilizes coincident photons, which are emitted from the location of each ion impact to map out regions of radiation sensitivity in integrated circuits and devices, circumventing the obstacle of focusing high-energy heavy ions. Several versions of the IPEM have been developed and implemented at Sandia National Laboratories (SNL). One such instrument has been utilized on the microbeam line of the 6 MV tandem accelerator at SNL. Another IPEM was designed for ex-vacu use at the 88'' cyclotron at Lawrence Berkeley National Laboratory (LBNL). Extensive engineering is involved in the development of these IPEM systems, including resolving issues with electronics, event timing, optics, phosphor selection, and mechanics. The various versions of the IPEM and the obstacles, as well as benefits associated with each will be presented. In addition, the current stage of IPEM development as a user instrument will be discussed in the context of recent results.

  9. Heavy ion radiation effects studies with ion photon emission microscopy.

    SciTech Connect

    Doyle, Barney Lee; Rossi, Paolo; Powell, Cody Joseph; Hattar, Khalid Mikhiel; Vizkelethy, Gyorgy; Branson, Janelle Villone

    2010-08-01

    The development of a new radiation effects microscopy (REM) technique is crucial as emerging semiconductor technologies demonstrate smaller feature sizes and thicker back end of line (BEOL) layers. To penetrate these materials and still deposit sufficient energy into the device to induce single event effects, high energy heavy ions are required. Ion photon emission microscopy (IPEM) is a technique that utilizes coincident photons, which are emitted from the location of each ion impact to map out regions of radiation sensitivity in integrated circuits and devices, circumventing the obstacle of focusing high-energy heavy ions. Several versions of the IPEM have been developed and implemented at Sandia National Laboratories (SNL). One such instrument has been utilized on the microbeam line of the 6 MV tandem accelerator at SNL. Another IPEM was designed for ex-vacu use at the 88 cyclotron at Lawrence Berkeley National Laboratory (LBNL). Extensive engineering is involved in the development of these IPEM systems, including resolving issues with electronics, event timing, optics, phosphor selection, and mechanics. The various versions of the IPEM and the obstacles, as well as benefits associated with each will be presented. In addition, the current stage of IPEM development as a user instrument will be discussed in the context of recent results.

  10. High resolution main-ion charge exchange spectroscopy in the DIII-D H-mode pedestal

    SciTech Connect

    Grierson, B. A.; Burrell, K. H.; Chrystal, C.; Groebner, R. J.; Haskey, S. R.; Kaplan, D. H.

    2016-09-12

    A new high spatial resolution main-ion (deuterium) charge-exchange spectroscopy system covering the tokamak boundary region has been installed on the DIII-D tokamak. Sixteen new edge main-ion charge-exchange recombination sightlines have been combined with nineteen impurity sightlines in a tangentially viewing geometry on the DIII-D midplane with an interleaving design that achieves 8 mm inter-channel radial resolution for detailed profiles of main-ion temperature, velocity, charge-exchange emission, and neutral beam emission. At the plasma boundary, we find a strong enhancement of the main-ion toroidal velocity that exceeds the impurity velocity by a factor of two. Furthermore, the unique combination of experimentally measured main-ion and impurity profiles provides a powerful quasi-neutrality constraint for reconstruction of tokamak H-mode pedestals.

  11. High resolution main-ion charge exchange spectroscopy in the DIII-D H-mode pedestal

    DOE PAGES

    Grierson, B. A.; Burrell, K. H.; Chrystal, C.; ...

    2016-09-12

    A new high spatial resolution main-ion (deuterium) charge-exchange spectroscopy system covering the tokamak boundary region has been installed on the DIII-D tokamak. Sixteen new edge main-ion charge-exchange recombination sightlines have been combined with nineteen impurity sightlines in a tangentially viewing geometry on the DIII-D midplane with an interleaving design that achieves 8 mm inter-channel radial resolution for detailed profiles of main-ion temperature, velocity, charge-exchange emission, and neutral beam emission. At the plasma boundary, we find a strong enhancement of the main-ion toroidal velocity that exceeds the impurity velocity by a factor of two. Furthermore, the unique combination of experimentally measuredmore » main-ion and impurity profiles provides a powerful quasi-neutrality constraint for reconstruction of tokamak H-mode pedestals.« less

  12. High resolution main-ion charge exchange spectroscopy in the DIII-D H-mode pedestal

    SciTech Connect

    Grierson, B. A.; Burrell, K. H.; Chrystal, C.; Groebner, R. J.; Haskey, S. R.; Kaplan, D. H.

    2016-09-12

    A new high spatial resolution main-ion (deuterium) charge-exchange spectroscopy system covering the tokamak boundary region has been installed on the DIII-D tokamak. Sixteen new edge main-ion charge-exchange recombination sightlines have been combined with nineteen impurity sightlines in a tangentially viewing geometry on the DIII-D midplane with an interleaving design that achieves 8 mm inter-channel radial resolution for detailed profiles of main-ion temperature, velocity, charge-exchange emission, and neutral beam emission. At the plasma boundary, we find a strong enhancement of the main-ion toroidal velocity that exceeds the impurity velocity by a factor of two. Furthermore, the unique combination of experimentally measured main-ion and impurity profiles provides a powerful quasi-neutrality constraint for reconstruction of tokamak H-mode pedestals.

  13. High resolution main-ion charge exchange spectroscopy in the DIII-D H-mode pedestal

    NASA Astrophysics Data System (ADS)

    Grierson, B. A.; Burrell, K. H.; Chrystal, C.; Groebner, R. J.; Haskey, S. R.; Kaplan, D. H.

    2016-11-01

    A new high spatial resolution main-ion (deuterium) charge-exchange spectroscopy system covering the tokamak boundary region has been installed on the DIII-D tokamak. Sixteen new edge main-ion charge-exchange recombination sightlines have been combined with nineteen impurity sightlines in a tangentially viewing geometry on the DIII-D midplane with an interleaving design that achieves 8 mm inter-channel radial resolution for detailed profiles of main-ion temperature, velocity, charge-exchange emission, and neutral beam emission. At the plasma boundary, we find a strong enhancement of the main-ion toroidal velocity that exceeds the impurity velocity by a factor of two. The unique combination of experimentally measured main-ion and impurity profiles provides a powerful quasi-neutrality constraint for reconstruction of tokamak H-mode pedestals.

  14. Reorientation of the crystalline planes in confined single crystal nickel nanorods induced by heavy ion irradiation

    NASA Astrophysics Data System (ADS)

    Misra, Abha; Tyagi, Pawan K.; Rai, Padmnabh; Misra, D. S.; Ghatak, Jay; Satyam, P. V.; Avasthi, D. K.

    2006-08-01

    In a recent letter Tyagi et al. [Appl. Phys. Lett. 86, 253110 (2005)] have reported the special orientation of nickel planes inside multiwalled carbon nanotubes (MWCNTs) with respect to the tube axis. Heavy ion irradiation has been performed with 1.5MeV Au2+ and 100MeV Au7+ ions on these nickel filled MWCNTs at fluences ranging from 1012to1015ions/cm2 at room temperature. Ion-induced modifications have been studied using high-resolution transmission electron microscopy. The diffraction pattern and the lattice imaging showed the presence of ion-induced planar defects on the tube walls and completely amorphized encapsulated nickel nanorods. The results are discussed in terms of thermal spike model.

  15. Angular distributions of sputtered atoms for low-energy heavy ions, medium ions and light ions

    NASA Astrophysics Data System (ADS)

    Yamamura, Yasunori; Mizuno, Yoshiyuki; Kimura, Hidetoshi

    1986-03-01

    The angular distributions of sputtered atoms for the near-threshold sputtering of heavy ions, medium ions, and light ions have been investigated by a few-collision model and the ACAT computer simulation code. For heavy-ion sputtering the preferential angle of sputtered atoms is about 50° which is measured from the surface normal, while in the case of the near-threshold light-ion sputtering the preferential angles are nearly equal to the surface normal and do not depend on angle of incidence. It is found that the agreement between the ACAT preferential angles and theoretical values due to a few-collision model is very good.

  16. Heavy Ion Reaction Modeling for Hadrontherapy Applications

    SciTech Connect

    Cerutti, F.; Ferrari, A.; Enghardt, W.; Gadioli, E.; Mairani, A.; Parodi, K.; Sommerer, F.

    2007-10-26

    A comprehensive and reliable description of nucleus-nucleus interactions represents a crucial need in different interdisciplinary fields. In particular, hadrontherapy monitoring by means of in-beam positron emission tomography (PET) requires, in addition to measuring, the capability of calculating the activity of {beta}{sup +}-decaying nuclei produced in the irradiated tissue. For this purpose, in view of treatment monitoring at the Heidelberg Ion Therapy (HIT) facility, the transport and interaction Monte Carlo code FLUKA is a promising candidate. It is provided with the description of heavy ion reactions at intermediate and low energies by two specific event generators. In-beam PET experiments performed at GSI for a few beam-target combinations have been simulated and first comparisons between the measured and calculated {beta}{sup +}-activity are available.

  17. Focal-surface detector for heavy ions

    DOEpatents

    Erskine, John R.; Braid, Thomas H.; Stoltzfus, Joseph C.

    1979-01-01

    A detector of the properties of individual charged particles in a beam includes a gridded ionization chamber, a cathode, a plurality of resistive-wire proportional counters, a plurality of anode sections, and means for controlling the composition and pressure of gas in the chamber. Signals generated in response to the passage of charged particles can be processed to identify the energy of the particles, their loss of energy per unit distance in an absorber, and their angle of incidence. In conjunction with a magnetic spectrograph, the signals can be used to identify particles and their state of charge. The detector is especially useful for analyzing beams of heavy ions, defined as ions of atomic mass greater than 10 atomic mass units.

  18. Material Removes Heavy Metal Ions From Water

    NASA Technical Reports Server (NTRS)

    Philipp, Warren H., Jr.; Street, Kenneth W.; Hill, Carol; Savino, Joseph M.

    1995-01-01

    New high capacity ion-exchange polymer material removes toxic metal cations from contaminated water. Offers several advantages. High sensitivities for such heavy metals as lead, cadmium, and copper and capable of reducing concentrations in aqueous solutions to parts-per-billion range. Removes cations even when calcium present. Material made into variety of forms, such as thin films, coatings, pellets, and fibers. As result, adapted to many applications to purify contaminated water, usually hard wherever found, whether in wastewater-treatment systems, lakes, ponds, industrial plants, or homes. Another important feature that adsorbed metals easily reclaimed by either destructive or nondestructive process. Other tests show ion-exchange polymer made inexpensively; easy to use; strong, flexible, not easily torn; and chemically stable in storage, in aqueous solutions, and in acidic or basic solution.

  19. Material Removes Heavy Metal Ions From Water

    NASA Technical Reports Server (NTRS)

    Philipp, Warren H., Jr.; Street, Kenneth W.; Hill, Carol; Savino, Joseph M.

    1995-01-01

    New high capacity ion-exchange polymer material removes toxic metal cations from contaminated water. Offers several advantages. High sensitivities for such heavy metals as lead, cadmium, and copper and capable of reducing concentrations in aqueous solutions to parts-per-billion range. Removes cations even when calcium present. Material made into variety of forms, such as thin films, coatings, pellets, and fibers. As result, adapted to many applications to purify contaminated water, usually hard wherever found, whether in wastewater-treatment systems, lakes, ponds, industrial plants, or homes. Another important feature that adsorbed metals easily reclaimed by either destructive or nondestructive process. Other tests show ion-exchange polymer made inexpensively; easy to use; strong, flexible, not easily torn; and chemically stable in storage, in aqueous solutions, and in acidic or basic solution.

  20. Bremsstrahlung from relativistic heavy ions in matter

    SciTech Connect

    Soerensen, Allan H.

    2010-02-15

    The emission of electromagnetic radiation by relativistic bare heavy ions penetrating ordinary matter is investigated. Our main aim is to determine the bremsstrahlung which we define as the radiation emitted when the projectile does not break up. It pertains to collisions without nuclear contact ('ultraperipheral collisions'). Requirement of coherent action of the nucleons in order to keep the penetrating projectile intact limits bremsstrahlung to relatively soft photons. The spectrum shows a resonance structure with peak position near 2{gamma} times the position of the giant dipole resonance, that is, near 25{gamma} MeV for a lead ion ({gamma}{identical_to}E/Mc{sup 2} is the Lorentz factor of the projectile of energy E and mass M). The maximum exceeds the bremsstrahlung from a hypothetical structureless, pointlike particle of the same charge and mass as the incoming nucleus, but rapid depletion follows on the high-energy side of the peak. As a result of its relative softness, bremsstrahlung never dominates the energy-loss process for heavy ions. As to the emission of electromagnetic radiation in collisions with nuclear break-up, it appears modest when pertaining to incoherent action of the projectile nucleons in noncontact collisions. In collisions with nuclear contact, though, substantial radiation is emitted. It overshoots the bremsstrahlung. However, despite the violence of contact events, the associated photon emission only exceeds the radiation from a hypothetical structureless pointlike nucleus [emitted energy per unit photon-energy interval essentially constant up to ({gamma}-1)Mc{sup 2}] at relatively low photon energies (for lead roughly below 0.2{gamma} GeV, a limit which is about an order of magnitude above the position of the bremsstrahlung peak). Results are presented for bare lead ions penetrating a solid lead target at energies of 158 GeV/n ({gamma}=170) and beyond.

  1. A heavy ion spectrometer system for the measurement of projectile fragmentation of relativistic heavy ions

    SciTech Connect

    Engelage, J.; Crawford, H.J.; Greiner, L.; Kuo, C.

    1996-06-01

    The Heavy Ion Spectrometer System (HISS) at the LBL Bevalac provided a unique facility for measuring projectile fragmentation cross sections important in deconvolving the Galactic Cosmic Ray (GCR) source composition. The general characteristics of the apparatus specific to this application are described and the main features of the event reconstruction and analysis used in the TRANSPORT experiment are discussed.

  2. Multiplicity and theremalization time in heavy-ions collisions

    NASA Astrophysics Data System (ADS)

    Aref'eva, Irina

    2016-10-01

    We present a concise review of quark-gluon plasma formation in heavy-ions collisions within the holographic approach. In particular, we discuss how to get the total multiplicity in heavy ions collision to fit the recent experimental data. We also discuss theoretical estimations of time formation of QGP in heavy ions collision and show that different observables can give the different times of QGP formation.

  3. Quantum Electrodynamics Effects in Heavy Ions and Atoms

    SciTech Connect

    Shabaev, V. M.; Andreev, O. V.; Bondarev, A. I.; Glazov, D. A.; Kozhedub, Y. S.; Maiorova, A. V.; Tupitsyn, I. I.; Plunien, G.; Volotka, A. V.

    2011-05-11

    Quantum electrodynamics theory of heavy ions and atoms is considered. The current status of calculations of the binding energies, the hyperfine splitting and g factor values in heavy few-electron ions is reviewed. The theoretical predictions are compared with available experimental data. A special attention is focused on tests of quantum electrodynamics in strong electromagnetic fields and on determination of the fundamental constants. Recent progress in calculations of the parity nonconservation effects with heavy atoms and ions is also reported.

  4. Performance predictions for a laser-intensified thermal beam for use in high-resolution focused-ion-beam instruments

    NASA Astrophysics Data System (ADS)

    Wouters, S. H. W.; ten Haaf, G.; Notermans, R. P. M. J. W.; Debernardi, N.; Mutsaers, P. H. A.; Luiten, O. J.; Vredenbregt, E. J. D.

    2014-12-01

    Photoionization of a laser-cooled and compressed atomic beam from a high-flux thermal source can be used to create a high-brightness ion beam for use in focused-ion-beam instruments. Here we show using calculations and Doppler cooling simulations that an atomic rubidium beam with an equivalent brightness of 2.1 ×107 A /(m 2 sr eV ) can be created using a compact 5 cm long two-dimensional magneto-optical compressor. If this can be conserved during the photoionization process, this leads to an ion beam brightness an order of magnitude higher than produced by a liquid metal ion source. The source is also capable of producing a flux of 6.2 ×109 s -1 that results in a substantial beam current of 1 nA once fully ionized.

  5. Developments in accelerators for heavy ion fusion

    SciTech Connect

    Keefe, D.

    1985-05-01

    The long term goal of Heavy Ion Fusion (HIF) is the development of an accelerator with the large beam power, large beam stored-energy, and high brightness needed to implode small deuterium-tritium capsules for fusion power. While studies of an rf linac/storage ring combination as an inertial fusion driver continue in Japan and Europe, the US program in recent times has concentrated on the study of the suitability of linear induction acceleration of ions for this purpose. Novel features required include use of multiple beams, beam current amplification in the linac, and manipulation of long beam bunches with a large velocity difference between head and tail. Recent experiments with an intense bright beam of cesium ions have established that much higher currents can be transported in a long quadrupole system than was believed possible a few years ago. A proof-of-principle ion induction linac to demonstrate beam current amplification with multiple beams is at present being fabricated at LBL. 28 refs., 4 figs.

  6. Linear ion-trap MSn with high resolution mass spectrometry reveals structural diversity of epidermal 1-O-acyl ceramide family in mouse epidermis.

    PubMed

    Lin, Meei-Hua; Miner, Jeffery; Turk, John; Hsu, Fong-Fu

    2017-02-02

    1-O-acylceramide is a new class of epidermal ceramide found in humans and mice. Here, we report ESI linear ion-trap (LIT) multiple stage mass spectrometric (MSn) approach with high resolution towards structural characterization of this lipid family isolated from mice. Molecular species desorbed as the [M + H]+ ions was subjected to LIT MS2 to yield predominately the [M + H - H2O]+ ions, followed by MS3 to cleave the 1-O-acyl residue to yield the [M + H - H2O - (1-O-fatty acid)]+ ions. The structures of the N-acyl chain and long-chain base (LCB) of the molecule were determined by MS4 on ([M + H - H2O - (1-O-fatty acid)]+) ions that yielded multiple sets of specific ions. Using this approach, isomers varied in the 1-O-acyl (from 14:0- to 26:0-O-acyl) and N-acyl chains (from 20:0- to 26:0-N-acyl) with 18:1-sphingosine as the major LCB were found for the entire family. Minor isomers consisting of 16:1- 17:1-, 18:2-, and 19:1-sphingosine LCB, with odd fatty acyl chain, or with monounsaturated N- or O- fatty acyl substituents were also identified. An estimation of more than 700 1-O-acylceramide species, largely isobaric isomers are present, underscoring the complexity of this ceramide family.

  7. Local brain heavy ion irradiation induced Immunosuppression

    NASA Astrophysics Data System (ADS)

    Lei, Runhong; Deng, Yulin; Huiyang Zhu, Bitlife.; Zhao, Tuo; Wang, Hailong; Yu, Yingqi; Ma, Hong; Wang, Xiao; Zhuang, Fengyuan; Qing, Hong

    Purpose: To investigate the long term effect of acute local brain heavy ion irradiation on the peripheral immune system in rat model. Methodology: Only the brain of adult male Wistar rats were radiated by heavy ions at the dose of 15 Gy. One, two and three months after irradiation, thymus and spleen were analyzed by four ways. Tunel assay was performed to evaluate the percentage of apoptotic cells in thymus and spleen, level of Inflammatory cytokines (IL-2, IL-6, SSAO, and TNF-α) was detected by ELISA assay, the differentiation of thymus T lymphocyte subsets were measured by flow cytometry and the relative expression levels of genes related to thymus immune cell development were measured by using quantitative real-time PCR. Results: Thymus and spleen showed significant atrophy from one month to three months after irradiation. A high level of apoptosis in thymus and spleen were obtained and the latter was more vulnerable, also, high level of inflammatory cytokines were found. Genes (c-kit, Rag1, Rag2 and Sca1) related to thymus lymphocytes’ development were down-regulated. Conclusion: Local area radiation in the rat brain would cause the immunosuppression, especially, the losing of cell-mediated immune functions. In this model, radiation caused inflammation and then induced apoptosis of cells in the immune organs, which contributed to immunosuppression.

  8. Hydrodynamic approaches in relativistic heavy ion reactions

    NASA Astrophysics Data System (ADS)

    Derradi de Souza, R.; Koide, T.; Kodama, T.

    2016-01-01

    We review several facets of the hydrodynamic description of the relativistic heavy ion collisions, starting from the historical motivation to the present understandings of the observed collective aspects of experimental data, especially those of the most recent RHIC and LHC results. In this report, we particularly focus on the conceptual questions and the physical foundations of the validity of the hydrodynamic approach itself. We also discuss recent efforts to clarify some of the points in this direction, such as the various forms of derivations of relativistic hydrodynamics together with the limitations intrinsic to the traditional approaches, variational approaches, known analytic solutions for special cases, and several new theoretical developments. Throughout this review, we stress the role of course-graining procedure in the hydrodynamic description and discuss its relation to the physical observables through the analysis of a hydrodynamic mapping of a microscopic transport model. Several questions to be answered to clarify the physics of collective phenomena in the relativistic heavy ion collisions are pointed out.

  9. Chamber transport for heavy ion fusion

    NASA Astrophysics Data System (ADS)

    Olson, Craig L.

    2014-01-01

    A brief review is given of research on chamber transport for HIF (heavy ion fusion) dating from the first HIF Workshop in 1976 to the present. Chamber transport modes are categorized into ballistic transport modes and channel-like modes. Four major HIF reactor studies are summarized (HIBALL-II, HYLIFE-II, Prometheus-H, OSIRIS), with emphasis on the chamber transport environment. In general, many beams are used to provide the required symmetry and to permit focusing to the required small spots. Target parameters are then discussed, with a summary of the individual heavy ion beam parameters required for HIF. The beam parameters are then classified as to their line charge density and perveance, with special emphasis on the perveance limits for radial space charge spreading, for the space charge limiting current, and for the magnetic (Alfven) limiting current. The major experiments on ballistic transport (SFFE, Sabre beamlets, GAMBLE II, NTX, NDCX) are summarized, with specific reference to the axial electron trapping limit for charge neutralization. The major experiments on channel-like transport (GAMBLE II channel, GAMBLE II self-pinch, LBNL channels, GSI channels) are discussed. The status of current research on HIF chamber transport is summarized, and the value of future NDCX-II transport experiments for the future of HIF is noted.

  10. Induction accelerator development for heavy ion fusion

    SciTech Connect

    Reginato, L.L.

    1993-05-01

    For approximately a decade, the Heavy Ion Fusion Accelerator Research (HIFAR) group at LBL has been exploring the use of induction accelerators with multiple beams as the driver for inertial fusion targets. Scaled experiments have investigated the transport of space charge dominated beams (SBTE), and the current amplification and transverse emittance control in induction linacs (MBE-4) with very encouraging results. In order to study many of the beam manipulations required by a driver and to further develop economically competitive technology, a proposal has been made in partnership with LLNL to build a 10 MeV accelerator and to conduct a series of experiments collectively called the Induction Linac System Experiments (ILSE). The major components critical to the ILSE accelerator are currently under development. We have constructed a full scale induction module and we have tested a number of amorphous magnetic materials developed by Allied Signal to establish an overall optimal design. The electric and magnetic quadrupoles critical to the transport and focusing of heavy ion beams are also under development The hardware is intended to be economically competitive for a driver without sacrificing any of the physics or performance requirements. This paper will concentrate on the recent developments and tests of the major components required by the ILSE accelerator.

  11. High gluon densities in heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Blaizot, Jean-Paul

    2017-03-01

    The early stages of heavy ion collisions are dominated by high density systems of gluons that carry each a small fraction x of the momenta of the colliding nucleons. A distinguishing feature of such systems is the phenomenon of ‘saturation’ which tames the expected growth of the gluon density as the energy of the collision increases. The onset of saturation occurs at a particular transverse momentum scale, the ‘saturation momentum’, that emerges dynamically and that marks the onset of non-linear gluon interactions. At high energy, and for large nuclei, the saturation momentum is large compared to the typical hadronic scale, making high density gluons amenable to a description with weak coupling techniques. This paper reviews some of the challenges faced in the study of such dense systems of small x gluons, and of the progress made in addressing them. The focus is on conceptual issues, and the presentation is both pedagogical, and critical. Examples where high gluon density could play a visible role in heavy ion collisions are briefly discussed at the end, for illustration purpose.

  12. Mutagenic effects of heavy ions in bacteria

    NASA Astrophysics Data System (ADS)

    Krasavin, E. A.; Kozubek, S.; Amirtayev, K. G.; Tokarova, B.; Bonev, M.

    The peculiarities and mechanisms of the mutagenic action of γ-rays and heavy ions on bacterial cells have been investigated. Direct mutations in the lac-operon of E. coli in wild type cells and repair deficient strains have been detected. Furthermore, the induction of revertants in Salmonella tester strains was measured. It was found that the mutation rate was a linear-quadratic function of dose in the case of both γ-rays and heavy ions with LET up to 200 keV/μm. The relative biological effectiveness (RBE) increased with LET up to 20 keV/μm. Low mutation rates were observed in repair deficient mutants with a block of SOS-induction. The induction of SOS-repair by ionizing radiation has been investigated by means of the ``SOS-chromotest'' and λ-prophage induction. It was shown that the intensity of the SOS-induction in E. coli increased with increasing LET up to 40-60 keV/μm.

  13. First identification of 5,11-dideoxytetrodotoxin in marine animals, and characterization of major fragment ions of tetrodotoxin and its analogs by high resolution ESI-MS/MS.

    PubMed

    Yotsu-Yamashita, Mari; Abe, Yuka; Kudo, Yuta; Ritson-Williams, Raphael; Paul, Valerie J; Konoki, Keiichi; Cho, Yuko; Adachi, Masaatsu; Imazu, Takuya; Nishikawa, Toshio; Isobe, Minoru

    2013-08-06

    Even though tetrodotoxin (TTX) is a widespread toxin in marine and terrestrial organisms, very little is known about the biosynthetic pathway used to produce it. By describing chemical structures of natural analogs of TTX, we can start to identify some of the precursors that might be important for TTX biosynthesis. In the present study, an analog of TTX, 5,11-dideoxyTTX, was identified for the first time in natural sources, the ovary of the pufferfish and the pharynx of a flatworm (planocerid sp. 1), by comparison with totally synthesized (-)-5,11-dideoxyTTX, using high resolution ESI-LC-MS. Based on the presence of 5,11-dideoxyTTX together with a series of known deoxy analogs, 5,6, 11-trideoxyTTX, 6,11-dideoxyTTX, 11-deoxyTTX, and 5-deoxyTTX, in these animals, we predicted two routes of stepwise oxidation pathways in the late stages of biosynthesis of TTX. Furthermore, high resolution masses of the major fragment ions of TTX, 6,11-dideoxyTTX, and 5,6,11-trideoxyTTX were also measured, and their molecular formulas and structures were predicted to compare them with each other. Although both TTX and 5,6,11-trideoxyTTX give major fragment ions that are very close, m/z 162.0660 and 162.1020, respectively, they are distinguishable and predicted to be different molecular formulas. These data will be useful for identification of TTXs using high resolution LC-MS/MS.

  14. First Identification of 5,11-Dideoxytetrodotoxin in Marine Animals, and Characterization of Major Fragment Ions of Tetrodotoxin and Its Analogs by High Resolution ESI-MS/MS

    PubMed Central

    Yotsu-Yamashita, Mari; Abe, Yuka; Kudo, Yuta; Ritson-Williams, Raphael; Paul, Valerie J.; Konoki, Keiichi; Cho, Yuko; Adachi, Masaatsu; Imazu, Takuya; Nishikawa, Toshio; Isobe, Minoru

    2013-01-01

    Even though tetrodotoxin (TTX) is a widespread toxin in marine and terrestrial organisms, very little is known about the biosynthetic pathway used to produce it. By describing chemical structures of natural analogs of TTX, we can start to identify some of the precursors that might be important for TTX biosynthesis. In the present study, an analog of TTX, 5,11-dideoxyTTX, was identified for the first time in natural sources, the ovary of the pufferfish and the pharynx of a flatworm (planocerid sp. 1), by comparison with totally synthesized (−)-5,11-dideoxyTTX, using high resolution ESI-LC-MS. Based on the presence of 5,11-dideoxyTTX together with a series of known deoxy analogs, 5,6,11-trideoxyTTX, 6,11-dideoxyTTX, 11-deoxyTTX, and 5-deoxyTTX, in these animals, we predicted two routes of stepwise oxidation pathways in the late stages of biosynthesis of TTX. Furthermore, high resolution masses of the major fragment ions of TTX, 6,11-dideoxyTTX, and 5,6,11-trideoxyTTX were also measured, and their molecular formulas and structures were predicted to compare them with each other. Although both TTX and 5,6,11-trideoxyTTX give major fragment ions that are very close, m/z 162.0660 and 162.1020, respectively, they are distinguishable and predicted to be different molecular formulas. These data will be useful for identification of TTXs using high resolution LC-MS/MS. PMID:23924959

  15. The Compact Muon Solenoid Heavy Ion program

    SciTech Connect

    Dr. Pablo Yepes

    2005-12-15

    The Pb-Pb center of mass energy at the LHC will exceed that of Au-Au collisions at RHIC (Relativistic Heavy Ion Collider) by nearly a factor of 30, providing exciting opportunities for addressing unique physics issues in a completely new energy domain. The interest of the Heavy Ion (HI) Physics at LHC is discussed in more detail in the LHC-USA white paper and the Compact Muon Solenoid (CMS) Heavy Ion proposal. A few highlights are presented in this document. Heavy ion collisions at LHC energies will explore regions of energy and particle density significantly beyond those reachable at RHIC. The energy density of the thermalized matter created at the LHC is estimated to be 20 times higher than at RHIC, implying an initial temperature, which is greater than at RHIC by more than a factor of two. The higher density of produced partons also allows a faster thermalization. As a consequence, the ratio of the quark-gluon plasma lifetime to the thermalization time increases by a factor of 10 over RHIC. Thus the hot, dense systems created in HI collisions at the LHC spend most of the time in a purely partonic state. The longer lifetime of the quark-gluon plasma state widens significantly the time window available to probe it experimentally. RHIC experiments have reported evidence for jet production in HI collisions and for suppression of high p{sub T} particle production. Those results open a new field of exploration of hot and dense nuclear matter. Even though RHIC has already broken ground, the production rates for jets with p{sub T} > 30 GeV are several orders of magnitude larger at the LHC than at RHIC, allowing for systematic studies with high statistics in a clean kinematic region. High p{sub T} quark and gluon jets can be used to study the hot hadronic medium produced in HI interactions. The larger Q{sup 2} causes jets to materialize very soon after the collision. They are thus embedded in and propagate through the dense environment as it forms and evolves. Through

  16. Fluorinated colloidal gold immunolabels for imaging select proteins in parallel with lipids using high-resolution secondary ion mass spectrometry

    PubMed Central

    Wilson, Robert L.; Frisz, Jessica F.; Hanafin, William P.; Carpenter, Kevin J.; Hutcheon, Ian D.; Weber, Peter K.; Kraft, Mary L.

    2014-01-01

    The local abundance of specific lipid species near a membrane protein is hypothesized to influence the protein’s activity. The ability to simultaneously image the distributions of specific protein and lipid species in the cell membrane would facilitate testing these hypotheses. Recent advances in imaging the distribution of cell membrane lipids with mass spectrometry have created the desire for membrane protein probes that can be simultaneously imaged with isotope labeled lipids. Such probes would enable conclusive tests of whether specific proteins co-localize with particular lipid species. Here, we describe the development of fluorine-functionalized colloidal gold immunolabels that facilitate the detection and imaging of specific proteins in parallel with lipids in the plasma membrane using high-resolution SIMS performed with a NanoSIMS. First, we developed a method to functionalize colloidal gold nanoparticles with a partially fluorinated mixed monolayer that permitted NanoSIMS detection and rendered the functionalized nanoparticles dispersible in aqueous buffer. Then, to allow for selective protein labeling, we attached the fluorinated colloidal gold nanoparticles to the nonbinding portion of antibodies. By combining these functionalized immunolabels with metabolic incorporation of stable isotopes, we demonstrate that influenza hemagglutinin and cellular lipids can be imaged in parallel using NanoSIMS. These labels enable a general approach to simultaneously imaging specific proteins and lipids with high sensitivity and lateral resolution, which may be used to evaluate predictions of protein co-localization with specific lipid species. PMID:22284327

  17. Fluorinated colloidal gold immunolabels for imaging select proteins in parallel with lipids using high-resolution secondary ion mass spectrometry.

    PubMed

    Wilson, Robert L; Frisz, Jessica F; Hanafin, William P; Carpenter, Kevin J; Hutcheon, Ian D; Weber, Peter K; Kraft, Mary L

    2012-03-21

    The local abundance of specific lipid species near a membrane protein is hypothesized to influence the protein's activity. The ability to simultaneously image the distributions of specific protein and lipid species in the cell membrane would facilitate testing these hypotheses. Recent advances in imaging the distribution of cell membrane lipids with mass spectrometry have created the desire for membrane protein probes that can be simultaneously imaged with isotope labeled lipids. Such probes would enable conclusive tests to determine whether specific proteins colocalize with particular lipid species. Here, we describe the development of fluorine-functionalized colloidal gold immunolabels that facilitate the detection and imaging of specific proteins in parallel with lipids in the plasma membrane using high-resolution SIMS performed with a NanoSIMS. First, we developed a method to functionalize colloidal gold nanoparticles with a partially fluorinated mixed monolayer that permitted NanoSIMS detection and rendered the functionalized nanoparticles dispersible in aqueous buffer. Then, to allow for selective protein labeling, we attached the fluorinated colloidal gold nanoparticles to the nonbinding portion of antibodies. By combining these functionalized immunolabels with metabolic incorporation of stable isotopes, we demonstrate that influenza hemagglutinin and cellular lipids can be imaged in parallel using NanoSIMS. These labels enable a general approach to simultaneously imaging specific proteins and lipids with high sensitivity and lateral resolution, which may be used to evaluate predictions of protein colocalization with specific lipid species.

  18. High Current Ion Source Development for Heavy Ion Fusion

    SciTech Connect

    Westenskow, G A; Grote, D P; Kwan, J W

    2003-09-04

    We are developing high-current-density high-brightness sources for Heavy Ion Fusion applications. Heavy ion driven inertial fusion requires beams of high brightness in order to achieve high power density at the target for high target gain. At present, there are no existing ion source types that can readily meet all the driver HIF requirements, though sources exist which are adequate for present experiments and which with further development may achieve driver requirements. Our two major efforts have been on alumino-silicate sources and RF plasma sources. Experiments being performed on a 10-cm alumino-silicate source are described. To obtain a compact system for a HIF driver we are studying RF plasma sources where low current beamlets are combined to produce a high current beam. A 80-kV 20-{micro}s source has produced up to 5 mA of Ar{sup +} in a single beamlet. The extraction current density was 100 mA/cm{sup 2}. We present measurements of the extracted current density as a function of RF power and gas pressure, current density uniformity, emittance, and energy dispersion (due to charge exchange).

  19. [Rapid screening and confirming carcinogenic banned azo colorants in textiles by high performance liquid chromatography-linear ion trap/orbitrap high-resolution mass spectrometry].

    PubMed

    Yun, Huan; Liu, Xin; Wang, Jing; Yan, Hua; Cui, Fengyun; Zhang, Zhaohui

    2013-09-01

    A method of high performance liquid chromatography-linear ion trap/orbitrap highresolution mass spectrometry (HPLC-LTP/Orbitrap MS) was ued to screen and confirm-banned azo colorants in textiles rapidly. The analytes were reduced to carcinogenic aromatic amines with sodium dithionite in citrate buffer solution. The reduced solution was extracted bydiatomite, and loadd onto an Acquity UPLC BEH C18 column (50 mm x 2.1 MM. 1.7 microm) with a gradient elution of methanol and 0.1% (v/v) methane acid aqueous solution, and finally detected by linear ion trap/orbitrap high-resolution mass spectrometry in positive ESI mode. In mass spectrometry method, the MS spectrum of high-resolution and the collision induced dissociation (CID) spectrum of data-dependent scan mode were used for screening analysis and conformation, respectively. The calibration curves showed a good linearity in the range of 0.05 -2.00 mg/b, and the correlation coefficients (r) were higher than 0.99. By detecting spiked samples, the limits of quantification were 0.08 mg/kg for all the residues and the recoveries were in the range of 65.5% - 111.5% with the relative standard deviations (RSDs) between 0.87% and 2.49%. The results indicate that the method is simple, rapid, sensitive and suitable for the qualitative and quantitative analysis of carcinogenic aromatic amines in textiles.

  20. High-resolution mass-analyzed threshold ion spectrum of Argon obtained on beamline 9.0.2.2

    SciTech Connect

    Hsu, C.W.; Lu, K.T.; Evans, M.

    1997-04-01

    The first mass analyzed threshold ion (MATI) spectrum using dc electric fields and a continuous wave light source has been obtained on End Station 2 of the Chemical Dynamics Beamline (9.0.2.2) at the Advanced Light Source. MATI provides researchers with fundamental spectroscopic information about atomic and molecular ions with the added advantage of mass analysis. The MATI technique involves the detection of ions formed by field ionization of long-lived high-n Rydberg states approaching an ionization threshold. The MATI apparatus consists of a differentially pumped supersonic molecular beam source, a photoionization region followed by a series of electrostatic lenses, a quadrupole mass spectrometer, and a Daly-type detector. The MATI technique can be used to probe the Rydberg states approaching an ionization continuum and yield information about the lifetimes of these states. In addition, MATI could be used to obtain the spectrum of a single species present in a sample mixture due to the mass selective nature of the experiment. MATI could also be used to form mass selected and state specific ions for use in ion molecule reaction experiments.

  1. Development of a High Resolution X-Ray Imaging Crystal Spectrometer for Measurement of Ion-Temperature and Rotation-Velocity Profiles in Fusion Energy Research Plasmas

    SciTech Connect

    Hill, K W; Broennimann, Ch; Eikenberry, E F; Ince-Cushman, A; Lee, S G; Rice, J E; Scott, S

    2008-01-29

    A new imaging high resolution x-ray crystal spectrometer (XCS) has been developed to measure continuous profiles of ion temperature and rotation velocity in fusion plasmas. Following proof-of-principle tests on the Alcator C-Mod tokamak and the NSTX spherical tokamak, and successful testing of a new silicon, pixilated detector with 1 MHz count rate capability per pixel, an imaging XCS is being designed to measure full profiles of Ti and vφ on C-Mod. The imaging XCS design has also been adopted for ITER. Ion-temperature uncertainty and minimum measurable rotation velocity are calculated for the C-Mod spectrometer. The affects of x-ray and uclear-radiation background on the measurement uncertainties are calculated to predict performance on ITER.

  2. Amorphization of Si(0 0 1) by ultra low energy (0.5-5 keV) ion implantation observed with high-resolution RBS

    NASA Astrophysics Data System (ADS)

    Kimura, K.; Agarwal, A.; Toyofuku, H.; Nakajima, K.; Gossmann, H.-J.

    1999-01-01

    The process of amorphization of Si(0 0 1) by ultra low energy (0.5 keV B + and 5 keV Si +) ion implantation is investigated using high-resolution RBS/channeling with a depth resolution better than 1 nm. In contrast to observations at higher implantation energies, amorphization by the ultra low energy ion implantation appears to proceed from the SiO 2/c-Si interface. The threshold dose for amorphization is determined to be ˜1 × 10 15 cm -2 for 0.5 keV B + and ˜1.5 × 10 14 cm -2 for 5 keV Si +. Comparison of the experimental results with TRIM simulations suggests that the SiO 2/c-Si interface behaves as a nucleation site for amorphization.

  3. Characterizing a switching reagent ion chemical ionization high resolution time of flight mass spectrometer: Standard additions, External calibrations, and Inlet response during SOAS

    NASA Astrophysics Data System (ADS)

    Brophy, P.; Farmer, D.

    2013-12-01

    A high-resolution time of flight chemical ionization mass spectrometer (HRToF-CIMS) with switching reagent ion source and low pressure, gas-phase inlet was deployed during the 2013 Southern Oxidant and Aerosol Study (SOAS) in Brent, Alabama. Acetate chemistry was employed for the detection of small acids and iodine chemistry for the detection of peroxy acids. Switching between the two ion sources was found to be possible on less than ten minute time scales with minimal artifacts observed. Online calibrations for formic acid on both the acetate and iodine sources were performed every hour using both standard addition techniques as well as external standard calibrations; offline formic acid calibrations were also conducted. Inlet responses were investigated though a number of experiments finding that the inlet has minimal hysteresis and rapid response times.

  4. Development of a High Resolution X-Ray Imaging Crystal Spectrometer for Measurement of Ion-Temperature and Rotation-Velocity Profiles in Fusion Energy Research Plasmas

    SciTech Connect

    Hill, K W; Broennimann, Ch; Eikenberry, E F; Ince-Cushman, A; Lee, S G; Rice, J E; Scott, S

    2008-02-27

    A new imaging high resolution x-ray crystal spectrometer (XCS) has been developed to measure continuous profiles of ion temperature and rotation velocity in fusion plasmas. Following proof-of-principle tests on the Alcator C-Mod tokamak and the NSTX spherical tokamak, and successful testing of a new silicon, pixilated detector with 1MHz count rate capability per pixel, an imaging XCS is being designed to measure full profiles of Ti and vφ on C-Mod. The imaging XCS design has also been adopted for ITER. Ion-temperature uncertainty and minimum measurable rotation velocity are calculated for the C-Mod spectrometer. The affects of x-ray and nuclear-radiation background on the measurement uncertainties are calculated to predict performance on ITER.

  5. Effects of heavy-ion irradiation on FeSe

    NASA Astrophysics Data System (ADS)

    Sun, Yue; Park, Akiyoshi; Pyon, Sunseng; Tamegai, Tsuyoshi; Kambara, Tadashi; Ichinose, Ataru

    2017-03-01

    We report the effects of heavy-ion irradiation on FeSe single crystals by irradiating uranium up to a dose-equivalent matching field of Bϕ=16 T. Almost continuous columnar defects along the c axis with a diameter of ˜10 nm are confirmed by high-resolution transmission electron microscopy. Tc is found to be suppressed by introducing columnar defects at a rate of d Tc/d Bϕ˜-0.29 K/T, which is much larger than those observed in iron pnictides. This unexpected large suppression of Tc in FeSe is discussed in relation to the large diameter of the columnar defects as well as its unique band structure with a remarkably small Fermi energy. The critical current density is first dramatically enhanced with irradiation reaching a value over ˜2 ×105A /cm2 (˜5 times larger than that of the pristine sample) at 2 K (self-field) with Bϕ=2 T, then gradually suppressed with increasing Bϕ. The δ l pinning associated with charge-carrier mean-free-path fluctuations and the δ Tc pinning associated with spatial fluctuations of the transition temperature are found to coexist in the pristine FeSe, while the irradiation increases the contribution from δ l pinning and makes it dominant over Bϕ=4 T.

  6. Heavy ion radiobiology for hadrontherapy and space radiation protection.

    PubMed

    Durante, Marco

    2004-12-01

    Research in the field of biological effects of heavy charged particles is needed for both heavy-ion therapy (hadrontherapy) and protection from the exposure to galactic cosmic radiation in long-term manned space missions. Although the exposure conditions (e.g. high- vs. low-dose rate) and relevant endpoints (e.g. cell killing vs. neoplastic transformation) are different in the two fields, it is clear that a substantial overlap exists in several research topics. Three such topics are discussed in this short review: individual radiosensitivity, mixed radiation fields, and late stochastic effects of heavy ions. In addition, researchers involved either in experimental studies on space radiation protection or heavy-ion therapy will basically use the same accelerator facilities. It seems to be important that novel accelerator facilities planned (or under construction) for heavy-ion therapy reserve a substantial amount of beamtime to basic studies of heavy-ion radiobiology and its applications in space radiation research.

  7. Algorithm for thorough background subtraction of high-resolution LC/MS data: application to obtain clean product ion spectra from nonselective collision-induced dissociation experiments.

    PubMed

    Zhang, Haiying; Grubb, Mary; Wu, Wei; Josephs, Jonathan; Humphreys, William G

    2009-04-01

    Nonselective collision-induced dissociation (CID) is a technique for producing fragmentation products for all ions generated in an ion source. It is typical of liquid chromatography/mass spectrometry (LC/MS) analysis of complex samples that matrix-related components may contribute to the resulting product ion spectra and confound the usefulness of this technique for structure interpretation. In this proof-of-principle study, a high-resolution LC/MS-based background subtraction algorithm was used to process the nonselective CID data to obtain clean product ion spectra for metabolites in human plasma samples. With buspirone and clozapine metabolites in human plasma as examples, this approach allowed for not only facile detection of metabolites of interest but also generation of their respective product ion spectra that were clean and free of matrix-related interferences. This was demonstrated with both an MS(E) technique (where E represents collision energy) with a quadrupole time-of-flight (QTOF) instrument and an in-source fragmentation technique with an LTQ Orbitrap instrument. The combined nonselective CID and background subtraction approach should allow for detection and structural interpretation of other types of sample analyses where control samples are obtained.

  8. Multiproduct high-resolution monoclonal antibody charge variant separations by pH gradient ion-exchange chromatography.

    PubMed

    Farnan, Dell; Moreno, G Tony

    2009-11-01

    In the biotechnology industry, ion-exchange chromatography is widely used for profiling the charge heterogeneity of proteins, including monoclonal antibodies. Ionic strength based ion exchange separations, while having excellent resolving power and robustness, are product specific and time-consuming to develop. In the present work, a pH gradient based separation using a cation exchange column is described and shown to be a multiproduct charge sensitive separation method for monoclonal antibodies. Simple mixtures of defined buffer components were used to generate the pH-gradients that separate closely related antibody species. The form of the pH gradient was controlled and optimized by the pump as well as the buffer composition if necessary. During this work, the buffer compositions for the separation were optimized in parallel for several MAbs. The data shows that the multiproduct method is optimal for all of the MAbs studied. Operational aspects of the separation such as column chemistry, column length, and sample matrix indicate a very robust method. The pH gradient ion-exchange method is demonstrated to have significant resolving power and peak capacities far in excess of what we would expect for ionic strength elution ion-exchange. Data obtained demonstrates that the separation is relatively insensitive to column length. Direct analysis (no buffer exchange) of samples in matrixes consistent with in-process manufacturing pools is demonstrated. Such a capability is extremely useful for the high throughput evaluation of in-process and final product samples.

  9. Surface structure and dipole moments of RbI(001) determined by high-resolution medium-energy ion scattering

    NASA Astrophysics Data System (ADS)

    Okazawa, T.; Hoshino, Y.; Nishimura, T.; Kido, Y.

    2001-11-01

    The surface structure of RbI(001) was determined directly by means of medium-energy ion scattering (MEIS) with a monolayer depth resolution. The rumpled surface structure determined here was compared with semi-classical shell-model calculations. On the basis of a simple model regarding the lattice site ion as a point charge accompanied by a dipole moment, we evaluated the dipole moments of the top- and second-layer I- and Rb+ ions self-consistently from the relaxed lattice positions determined by means of MEIS and from the polarizabilities estimated systematically from experimental refraction data. The balance between a short-range force and a long-range coulombic one determined the equilibrium positions of the top- and second-layer ions; these are consistent with those derived by means of MEIS within the experimental uncertainties of 0.02 Å. This indicates that the polarizablities derived from the refraction data and the interatomic (short-range) potentials of the Born-Mayer type are applicable.

  10. Conducting swift heavy ion track networks

    NASA Astrophysics Data System (ADS)

    Fink, D.; Kiv, A.; Fuks, D.; Saad, A.; Vacík, J.; Hnatowicz, V.; Chandra, A.

    2010-03-01

    In this paper, the electronic behavior of conducting swift heavy ion track networks is studied. On the one hand, the transient conductivity of ion tracks in metal oxides on silicon in status nascendi is exploited for this purpose, and on the other hand, conducting tracks are produced by ion irradiation of insulating membranes (either self-supported or deposited onto silicon substrates), subsequent etching and finally inserting conducting materials of whatever provenience (in this work preferentially electrolytes). Depending on their manufacture, the conducting tracks either act as electronically active or passive elements. When applying a voltage across individual tracks in the first case, one observes current spikes with negative differential resistances. These tracks interact among themselves, leading to phase-locked synchronous coupled oscillations with complex patterns that are quite similar to those emerging from neural networks. The other case corresponds to networks of electronically passive conducting tracks which become overall electronically active only through their collective interactions. Though the aforementioned effects had been experimentally described earlier, they are re-visited here to make clear that the corresponding systems have to be considered as being artificial neural networks. On this occasion, some new findings are added.

  11. Mass spectra of heavy ions near comet Halley

    NASA Technical Reports Server (NTRS)

    Korth, A.; Richter, A. K.; Loidl, A.; Anderson, K. A.; Carlson, C. W.

    1986-01-01

    The heavy-ion analyzer, RPA2-PICCA, aboard the Giotto spacecraft, detected the first cometary ions at a distance of about 1.05 million km from the nucleus of comet Halley. In the inner coma the major ions identified are associated with the H2O, CO and CO2 groups. Ions of larger atomic mass unit are also present, corresponding possibly to various hydrocarbons, heavy metals of the iron-group or to sulphur compounds.

  12. Mass spectra of heavy ions near comet Halley

    NASA Technical Reports Server (NTRS)

    Korth, A.; Richter, A. K.; Loidl, A.; Anderson, K. A.; Carlson, C. W.

    1986-01-01

    The heavy-ion analyzer, RPA2-PICCA, aboard the Giotto spacecraft, detected the first cometary ions at a distance of about 1.05 million km from the nucleus of comet Halley. In the inner coma the major ions identified are associated with the H2O, CO and CO2 groups. Ions of larger atomic mass unit are also present, corresponding possibly to various hydrocarbons, heavy metals of the iron-group or to sulphur compounds.

  13. Direct high-resolution ion beam-profile imaging using a position-sensitive Faraday cup array

    SciTech Connect

    Panitzsch, Lauri; Stalder, Michael; Wimmer-Schweingruber, Robert F.

    2009-11-15

    Ion sources have wide-spread use in a multitude of applications. For many, an accurate knowledge, or better, an accurate imaging, of the beam profile and intensity is an important criterion. We are developing an ion source to calibrate instruments for space-based measurements of solar wind and suprathermal particles in the energy range from below 1 keV/nuc to above 200 keV/nuc. In order to establish accurate beam profiles for calibration purposes, we have developed a new method based on an array of very small (diameter = 0.3 mm) Faraday cups. Here, we describe the experimental setup and discuss how to achieve several requirements such as a large thermal load due to the {approx}40W of beam power.

  14. High-resolution spectroscopy for Doppler-broadening ion temperature measurements of implosions at the National Ignition Facility

    SciTech Connect

    Koch, J. A.; Stewart, R. E.; Beiersdorfer, P.; Shepherd, R.; Schneider, M. B.; Miles, A. R.; Scott, H. A.; Smalyuk, V. A.; Hsing, W. W.

    2012-10-15

    Future implosion experiments at the national ignition facility (NIF) will endeavor to simultaneously measure electron and ion temperatures with temporal and spatial resolution in order to explore non-equilibrium temperature distributions and their relaxation toward equilibrium. In anticipation of these experiments, and with understanding of the constraints of the NIF facility environment, we have explored the use of Doppler broadening of mid-Z dopant emission lines, such as krypton He-{alpha} at 13 keV, as a diagnostic of time- and potentially space-resolved ion temperature. We have investigated a number of options analytically and with numerical raytracing, and we have identified several promising candidate spectrometer designs that meet the expected requirements of spectral and temporal resolution and data signal-to-noise ratio for gas-filled exploding pusher implosions, while providing maximum flexibility for use on a variety of experiments that potentially include burning plasma.

  15. Beam dynamics in heavy ion fusion

    SciTech Connect

    Seidl, P.

    1995-04-01

    A standard design for heavy ion fusion drivers under study in the US is an induction linac with electrostatic focusing at low energy and magnetic focusing at higher energy. The need to focus the intense beam to a few-millimeter size spot at the deuterium-tritium target establishes the emittance budget for the accelerator. Economic and technological considerations favor a larger number of beams in the low-energy, electrostatic-focusing section than in the high-energy, magnetic-focusing section. Combining four beams into a single focusing channel is a viable option, depending on the growth in emittance due to the combining process. Several significant beam dynamics issues that are, or have been, under active study are discussed: large space charge and image forces, beam wall clearances, halos, alignment, longitudinal instability, and bunch length control.

  16. Prompt processes in heavy ion reactions

    SciTech Connect

    Blann, M.; Remington, B.A.

    1987-12-01

    We test a relaxation model based on two body nucleon-nucleon scattering processes to interpret phenomena observed in heavy ion reactions. We use the Boltzmann Master Equation to accomplish this. By assuming that the projectile nucleons partition the total excitation with equal a-priori probability of all configurations, we are able to reproduce several sets of neutron spectra from /sup 20/Ne and /sup 12/C induced reactions on /sup 165/Ho and from reactions of /sup 40/Ar or /sup 40/Ca. We point out ambiguities in deducing angle-integrated energy spectra from double differential spectra. With no additional free parameters, our model successfully reproduces a large body of high energy ..gamma..-ray spectra by assuming an incoherent n-p-bremsstrahlung mechanism. 45 refs., 13 figs.

  17. Latchup in CMOS devices from heavy ions

    NASA Technical Reports Server (NTRS)

    Soliman, K.; Nichols, D. K.

    1983-01-01

    It is noted that complementary metal oxide semiconductor (CMOS) microcircuits are inherently latchup prone. The four-layer n-p-n-p structures formed from the parasitic pnp and npn transistors make up a silicon controlled rectifier. If properly biased, this rectifier may be triggered 'ON' by electrical transients, ionizing radiation, or a single heavy ion. This latchup phenomenon might lead to a loss of functionality or device burnout. Results are presented from tests on 19 different device types from six manufacturers which investigate their latchup sensitivity with argon and krypton beams. The parasitic npnp paths are identified in general, and a qualitative rationale is given for latchup susceptibility, along with a latchup cross section for each type of device. Also presented is the correlation between bit-flip sensitivity and latchup susceptibility.

  18. Latchup in CMOS devices from heavy ions

    NASA Technical Reports Server (NTRS)

    Soliman, K.; Nichols, D. K.

    1983-01-01

    It is noted that complementary metal oxide semiconductor (CMOS) microcircuits are inherently latchup prone. The four-layer n-p-n-p structures formed from the parasitic pnp and npn transistors make up a silicon controlled rectifier. If properly biased, this rectifier may be triggered 'ON' by electrical transients, ionizing radiation, or a single heavy ion. This latchup phenomenon might lead to a loss of functionality or device burnout. Results are presented from tests on 19 different device types from six manufacturers which investigate their latchup sensitivity with argon and krypton beams. The parasitic npnp paths are identified in general, and a qualitative rationale is given for latchup susceptibility, along with a latchup cross section for each type of device. Also presented is the correlation between bit-flip sensitivity and latchup susceptibility.

  19. Nuclei at HERA and heavy ion physics

    SciTech Connect

    Gavin, S.; Strikman, M.

    1995-12-31

    Copies of 16 viewgraph sets from a workshop held at Brookhaven National Laboratory, 17-18 November, 1995. Titles of talks: HERA: The Present; HERA: Potential with Nuclei; Review of Hadron-Lepton Nucleus Data; Fermilab E665: results in muon scattering; Interactions of Quarks and Gluons with Nuclear Matter; Rescattering in Nuclear Targets for Photoproduction and DIS; Structure Functions and Nuclear Effect at PHENIX; Probing Spin-Averaged and Spin-Dependent Parton Distributions Using the Solenoidal Tracker at RHIC (STAR); Jet Quenching in eA, pA, AA; Nuclear Gluon Shadowing via Continuum Lepton Pairs; What can we learn from HERA with a colliding heavy ion beam? The limiting curve of leading particles at infinite A; Coherent Production of Vector Mesons off Light Nuclei in DIS; A Model of High Parton Densities in PQCD; Gluon Production for Weizaecker-Williams Field in Nucleus-Nucleus Collisions; Summary Talk.

  20. Cold fission as heavy ion emission

    NASA Astrophysics Data System (ADS)

    Poenaru, D. N.; Maruhn, J. A.; Greiner, W.; Ivaşcu, M.; Mazilu, D.; Gherghescu, R.

    1987-09-01

    The last version of the analytical superasymmetric fission model is applied to study cold fission processes. Strong shell effects are present either in one or both fission fragments. A smooth behaviour is observed when the proton or the neutron numbers are changed by four units. Increasing Z and N, in the transuranium region, a sharp transition from asymmetry with a large peak-to-valley ratio to symmetry at Z=100 and/or N=164 is obtained. The transition toward asymmetry at higher Z and N is much smoother. The most probable cold fission light fragments from234U,236U,239Np and240Pu are100Zr,104Mo,106Mo and106Mo, respectively, in good agreement with experimental data. The unified treatment of alpha decay, heavy ion radioactivities and cold fission is illustrated for234U — the first nucleus in which all three groups have been already observed.

  1. Rapidity dependence in holographic heavy ion collisions

    DOE PAGES

    Wilke van der Schee; Schenke, Bjorn

    2015-12-11

    We present an attempt to closely mimic the initial stage of heavy ion collisions within holography, assuming a decoupling of longitudinal and transverse dynamics in the very early stage. We subsequently evolve the obtained initial state using state-of-the-art hydrodynamic simulations and compare results with experimental data. We present results for charged hadron pseudorapidity spectra and directed and elliptic flow as functions of pseudorapidity for √sNN = 200GeV Au-Au and 2.76TeV Pb-Pb collisions. As a result, the directed flow interestingly turns out to be quite sensitive to the viscosity. The results can explain qualitative features of the collisions, but the rapiditymore » spectra in our current model is narrower than the experimental data.« less

  2. Rapidity dependence in holographic heavy ion collisions

    SciTech Connect

    Wilke van der Schee; Schenke, Bjorn

    2015-12-11

    We present an attempt to closely mimic the initial stage of heavy ion collisions within holography, assuming a decoupling of longitudinal and transverse dynamics in the very early stage. We subsequently evolve the obtained initial state using state-of-the-art hydrodynamic simulations and compare results with experimental data. We present results for charged hadron pseudorapidity spectra and directed and elliptic flow as functions of pseudorapidity for √sNN = 200GeV Au-Au and 2.76TeV Pb-Pb collisions. As a result, the directed flow interestingly turns out to be quite sensitive to the viscosity. The results can explain qualitative features of the collisions, but the rapidity spectra in our current model is narrower than the experimental data.

  3. Superconducting heavy-ion linac at Argonne

    SciTech Connect

    Aron, J.; Benaroya, R.; Bollinger, L.M.; Clifft, B.G.; Johnson, K.W.; Nixon, J.M.; Markovich, P.; Pardo, R.C.; Shepard, K.W.

    1981-01-01

    The design, status, and performance of the first operating superconducting heavy-ion accelerator, a linac used to boost the energies of beams from a 9-MV tandem, is summarized. When completed in 1981, the linac will consist of 24 independently-phased split-ring niobium resonators operating at 97 MHz. This linac is designed to provide 29 MV of acceleration. Because of the modular character of the system, the linac has been operable and useful since mid-1978, when a beam was accelerated through 2 units and the first nuclear-physics experiments were preformed. Now, 16 resonators are in use, and a beam has been accelerated for approx. 6000 h. Resonator performance has been remarkably stable, in spite of vacuum accidents, and the linac as a whole operates reliably without operators in attendance during nights and weekends. The ease and speed with which the beam energy can be changed is proving to be unexpectedly valuable to users.

  4. Hadron Production in Heavy Ion Collisions

    SciTech Connect

    Ritter, Hans Georg; Xu, Nu

    2009-05-19

    Heavy ion collisions are an ideal tool to explore the QCD phase diagram. The goal is to study the equation of state (EOS) and to search for possible in-medium modifications of hadrons. By varying the collision energy a variety of regimes with their specific physics interest can be studied. At energies of a few GeV per nucleon, the regime where experiments were performed first at the Berkeley Bevalac and later at the Schwer-Ionen-Synchrotron (SIS) at GSI in Darmstadt, we study the equation of state of dense nuclear matter and try to identify in-medium modifications of hadrons. Towards higher energies, the regime of the Alternating Gradient Synchrotron (AGS) at the Brookhaven National Laboratory (BNL), the Super-Proton Synchrotron (SPS) at CERN, and the Relativistic Heavy Ion Collider (RHIC) at BNL, we expect to produce a new state of matter, the Quark-Gluon Plasma (QGP). The physics goal is to identify the QGP and to study its properties. By varying the energy, different forms of matter are produced. At low energies we study dense nuclear matter, similar to the type of matter neutron stars are made of. As the energy is increased the main constituents of the matter will change. Baryon excitations will become more prevalent (resonance matter). Eventually we produce deconfined partonic matter that is thought to be in the core of neutron stars and that existed in the early universe. At low energies a great variety of collective effects is observed and a rather good understanding of the particle production has been achieved, especially that of the most abundantly produced pions and kaons. Many observations can be interpreted as time-ordered emission of various particle species. It is possible to determine, albeit model dependent, the equation of state of nuclear matter. We also have seen indications, that the kaon mass, especially the mass of the K{sup +}, might be modified by the medium created in heavy ion collisions. At AGS energies and above, emphasis shifts towards

  5. Ion-cyclotron wave heating of heavy ions in the equatorial magnetosphere - A numerical simulation theory

    NASA Astrophysics Data System (ADS)

    Chen, M. W.; Hada, T.; Ashour-Abdalla, M.

    A 1-2/2 dimensional hybrid numerical simulation code is used to study the heating of cold H(+) ions and heavy ions by electromagnetic ion-cyclotron waves (ICWs) in the ring current region of the equatorial magnetosphere. Consideration is given to a plasma consisting of electrons, hot H(+) ions, and cold heavy ions in which the ICWs are driven by the temperature anisotropy of the hot protons. For large-amplitude ICWs, it is found that the cold H(+) ions are preferentially heated over the heavy ions although the cold H(+) ions are heated by a three-step process.

  6. Heavy-Ion Fusion Accelerator Research, 1992

    SciTech Connect

    Not Available

    1993-06-01

    The National Energy Strategy calls for a demonstration IFE power plant by the year 2025. The cornerstone of the plan to meet this ambitious goal is research and development for heavy-ion driver technology. A series of successes indicates that the technology being studied by the HIFAR Group -- the induction accelerator -- is a prime candidate for further technology development toward this long-range goal. The HIFAR program addresses the generation of high-power, high-brightness beams of heavy ions; the understanding of the scaling laws that apply in this hitherto little-explored physics regime; and the validation of new, potentially more economical accelerator strategies. Key specific elements to be addressed include: fundamental physical limits of transverse and longitudinal beam quality; development of induction modules for accelerators, along with multiple-beam hardware, at reasonable cost; acceleration of multiple beams, merging of the beams, and amplification of current without significant dilution of beam quality; final bunching, transport, and focusing onto a small target. In 1992, the HIFAR Program was concerned principally with the next step toward a driver: the design of ILSE, the Induction Linac Systems Experiments. ILSE will address most of the remaining beam-control and beam-manipulation issues at partial driver scale. A few parameters -- most importantly, the line charge density and consequently the size of the ILSE beams -- will be at full driver scale. A theory group closely integrated with the experimental groups continues supporting present-day work and looking ahead toward larger experiments and the eventual driver. Highlights of this long-range, driver-oriented research included continued investigations of longitudinal instability and some new insights into scaled experiments with which the authors might examine hard-to-calculate beam-dynamics phenomena.

  7. Bose condensation of nuclei in heavy ion collisions

    NASA Technical Reports Server (NTRS)

    Tripathi, Ram K.; Townsend, Lawrence W.

    1994-01-01

    Using a fully self-consistent quantum statistical model, we demonstrate the possibility of Bose condensation of nuclei in heavy ion collisions. The most favorable conditions of high densities and low temperatures are usually associated with astrophysical processes and may be difficult to achieve in heavy ion collisions. Nonetheless, some suggestions for the possible experimental verification of the existence of this phenomenon are made.

  8. Recent Progress in Isospin Physics with Heavy-Ion Reactions

    SciTech Connect

    Chen Liewen; Ko, Che Ming; Li Baoan

    2008-11-11

    We review recent progress in the determination of the subsaturation density behavior of the nuclear symmetry energy from heavy-ion collisions as well as the theoretical progress in probing the high density behavior of the symmetry energy in heavy-ion reactions induced by future high energy radioactive beams. Implications of these results for the nuclear effective interactions are also discussed.

  9. Induction linac drivers for commercial heavy-ion beam fusion

    SciTech Connect

    Keefe, D.

    1987-11-01

    This paper discusses induction linac drivers necessary to accelerate heavy ions at inertial fusion targets. Topics discussed are: driver configurations, the current-amplifying induction linac, high current beam behavior and emittance growth, new considerations for driver design, the heavy ion fusion systems study, and future studies. 13 refs., 6 figs., 1 tab. (LSP)

  10. Theoretical Concepts for Ultra-Relativistic Heavy Ion Collisions

    SciTech Connect

    McLerran,L.

    2009-07-27

    Various forms of matter may be produced in ultra-relativistic heavy ion collisions. These are the Quark GluonPlasma, the Color Glass Condensate , the Glasma and Quarkyoninc Matter. A novel effect that may beassociated with topological charge fluctuations is the Chiral Magnetic Effect. I explain these concepts andexplain how they may be seen in ultra-relatvistic heavy ion collisions

  11. NSAC Recommends a Relativistic Heavy-Ion Collider.

    ERIC Educational Resources Information Center

    Physics Today, 1984

    1984-01-01

    Describes the plan submitted by the Nuclear Science Advisory Committee to the Department of Energy and National Science Foundation urging construction of an ultrarelativistic heavy-ion collider designed to accelerate nucleon beams of ions as heavy as uranium. Discusses the process of selecting the type of facility as well as siting. (JM)

  12. Boltzmann-Langevin transport model for heavy-ion collisions

    SciTech Connect

    Ayik, S. |

    1994-06-01

    Heavy-ion collisions at intermediate energies exhibit catastrophic phenomena which requires descriptions based on stochastic transport models. First, the Boltzmann-Langevin model, which provides an example of such stochastic approaches, is briefly described. Then, a projection method for obtaining numerical solutions of the Boltzmann-Langevin equation is discussed. Finally, some applications of the model to heavy-ion collisions are presented.

  13. Variation in the uptake of nanoparticles by monolayer cultured cells using high resolution MeV ion beam imaging

    NASA Astrophysics Data System (ADS)

    Tao, Ye; Mi, Zhaohong; Vanga, Sudheer Kumar; Chen, Ce-Belle; Bettiol, Andrew A.; Watt, Frank

    2015-04-01

    Gold nanoparticle uptake by cells is being increasingly studied because of its potential in biomedical applications. In this work, we show how scanning transmission ion microscopy can be employed to visualize and quantify 50 nm gold nanoparticles taken up by individual cells. Preliminary studies have indicated that the cellular content of gold nanoparticles exhibits a wide variation (up to a factor of 10) among individual cells. This cell-to-cell variation can affect the efficiency of utilizing gold nanoparticles for therapeutic or diagnostic purposes.

  14. Helium ion microscopy and ultra-high-resolution scanning electron microscopy analysis of membrane-extracted cells reveals novel characteristics of the cytoskeleton of Giardia intestinalis.

    PubMed

    Gadelha, Ana Paula Rocha; Benchimol, Marlene; de Souza, Wanderley

    2015-06-01

    Giardia intestinalis presents a complex microtubular cytoskeleton formed by specialized structures, such as the adhesive disk, four pairs of flagella, the funis and the median body. The ultrastructural organization of the Giardia cytoskeleton has been analyzed using different microscopic techniques, including high-resolution scanning electron microscopy. Recent advances in scanning microscopy technology have opened a new venue for the characterization of cellular structures and include scanning probe microscopy techniques such as ultra-high-resolution scanning electron microscopy (UHRSEM) and helium ion microscopy (HIM). Here, we studied the organization of the cytoskeleton of G. intestinalis trophozoites using UHRSEM and HIM in membrane-extracted cells. The results revealed a number of new cytoskeletal elements associated with the lateral crest and the dorsal surface of the parasite. The fine structure of the banded collar was also observed. The marginal plates were seen linked to a network of filaments, which were continuous with filaments parallel to the main cell axis. Cytoplasmic filaments that supported the internal structures were seen by the first time. Using anti-actin antibody, we observed a labeling in these filamentous structures. Taken together, these data revealed new surface characteristics of the cytoskeleton of G. intestinalis and may contribute to an improved understanding of the structural organization of trophozoites. Copyright © 2015 Elsevier Inc. All rights reserved.

  15. Quantitative Protein Topography Analysis and High-Resolution Structure Prediction Using Hydroxyl Radical Labeling and Tandem-Ion Mass Spectrometry (MS)*

    PubMed Central

    Kaur, Parminder; Kiselar, Janna; Yang, Sichun; Chance, Mark R.

    2015-01-01

    Hydroxyl radical footprinting based MS for protein structure assessment has the goal of understanding ligand induced conformational changes and macromolecular interactions, for example, protein tertiary and quaternary structure, but the structural resolution provided by typical peptide-level quantification is limiting. In this work, we present experimental strategies using tandem-MS fragmentation to increase the spatial resolution of the technique to the single residue level to provide a high precision tool for molecular biophysics research. Overall, in this study we demonstrated an eightfold increase in structural resolution compared with peptide level assessments. In addition, to provide a quantitative analysis of residue based solvent accessibility and protein topography as a basis for high-resolution structure prediction; we illustrate strategies of data transformation using the relative reactivity of side chains as a normalization strategy and predict side-chain surface area from the footprinting data. We tested the methods by examination of Ca+2-calmodulin showing highly significant correlations between surface area and side-chain contact predictions for individual side chains and the crystal structure. Tandem ion based hydroxyl radical footprinting-MS provides quantitative high-resolution protein topology information in solution that can fill existing gaps in structure determination for large proteins and macromolecular complexes. PMID:25687570

  16. The structure of SrTiO3(001)-2 × 1 surface analyzed by high-resolution medium energy ion scattering coupled with ab initio calculations

    NASA Astrophysics Data System (ADS)

    Matsuda, Taishi; Yoshida, Yuki; Mitsuhara, Kei; Kido, Yoshiaki

    2013-06-01

    High-resolution medium energy ion scattering (MEIS) spectrometry coupled with photoelectron spectroscopy revealed unambiguously that the initial SrTiO3(001) surface chemically etched in a buffered NH4F-HF solution was perfectly terminated with a single-layer (SL) of TiO2(001) and annealing the surface at 600-800 °C in ultrahigh vacuum (UHV) led to a (2 × 1)-reconstructed surface terminated with a double-layer (DL) of TiO2(001). After annealing in UHV, rock-salt SrO(001) clusters with two atomic layer height grew epitaxially on the DL-TiO2(001)-2 × 1 surface with a coverage of 20%-30%. High-resolution MEIS in connection with ab initio calculations demonstrated the structure of the DL-TiO2(001)-2 × 1 surface close to that proposed by Erdman et al. [Nature (London) 419, 55 (2002)], 10.1038/nature01010 rather than that predicted by Herger et al. [Phys. Rev. Lett. 98, 076102 (2007)], 10.1103/PhysRevLett.98.076102. Based on the MEIS analysis combined with the ab initio calculations, we propose the most probable (2 × 1) surface structure.

  17. Quantitative protein topography analysis and high-resolution structure prediction using hydroxyl radical labeling and tandem-ion mass spectrometry (MS).

    PubMed

    Kaur, Parminder; Kiselar, Janna; Yang, Sichun; Chance, Mark R

    2015-04-01

    Hydroxyl radical footprinting based MS for protein structure assessment has the goal of understanding ligand induced conformational changes and macromolecular interactions, for example, protein tertiary and quaternary structure, but the structural resolution provided by typical peptide-level quantification is limiting. In this work, we present experimental strategies using tandem-MS fragmentation to increase the spatial resolution of the technique to the single residue level to provide a high precision tool for molecular biophysics research. Overall, in this study we demonstrated an eightfold increase in structural resolution compared with peptide level assessments. In addition, to provide a quantitative analysis of residue based solvent accessibility and protein topography as a basis for high-resolution structure prediction; we illustrate strategies of data transformation using the relative reactivity of side chains as a normalization strategy and predict side-chain surface area from the footprinting data. We tested the methods by examination of Ca(+2)-calmodulin showing highly significant correlations between surface area and side-chain contact predictions for individual side chains and the crystal structure. Tandem ion based hydroxyl radical footprinting-MS provides quantitative high-resolution protein topology information in solution that can fill existing gaps in structure determination for large proteins and macromolecular complexes.

  18. High-resolution (e, 2e + ion) study of electron-impact ionization and fragmentation of methane

    SciTech Connect

    Ren, Xueguang Pflüger, Thomas; Weyland, Marvin; Baek, Woon Yong; Rabus, Hans; Ullrich, Joachim; Dorn, Alexander

    2015-05-07

    The ionization and fragmentation of methane induced by low-energy (E{sub 0} = 66 eV) electron-impact is investigated using a reaction microscope. The momentum vectors of all three charged final state particles, two outgoing electrons, and one fragment ion, are detected in coincidence. Compared to the earlier study [Xu et al., J. Chem. Phys. 138, 134307 (2013)], considerable improvements to the instrumental mass and energy resolutions have been achieved. The fragment products CH{sub 4}{sup +}, CH{sub 3}{sup +}, CH{sub 2}{sup +}, CH{sup +}, and C{sup +} are clearly resolved. The binding energy resolution of ΔE = 2.0 eV is a factor of three better than in the earlier measurements. The fragmentation channels are investigated by measuring the ion kinetic energy distributions and the binding energy spectra. While being mostly in consistence with existing photoionization studies the results show differences including missing fragmentation channels and previously unseen channels.

  19. Imaging crystal spectrometer for high-resolution x-ray measurements on electron beam ion traps and tokamaks.

    PubMed

    Beiersdorfer, P; Magee, E W; Hell, N; Brown, G V

    2016-11-01

    We describe a crystal spectrometer implemented on the Livermore electron beam ion traps that employ two spherically bent quartz crystals and a cryogenically cooled back-illuminated charge-coupled device detector to measure x rays with a nominal resolving power of λ/Δλ ≥ 10 000. Its focusing properties allow us to record x rays either with the plane of dispersion perpendicular or parallel to the electron beam and, thus, to preferentially select one of the two linear x-ray polarization components. Moreover, by choice of dispersion plane and focussing conditions, we use the instrument either to image the distribution of the ions within the 2 cm long trap region, or to concentrate x rays of a given energy to a point on the detector, which optimizes the signal-to-noise ratio. We demonstrate the operation and utility of the new instrument by presenting spectra of Mo(34+), which prepares the instrument for use as a core impurity diagnostic on the NSTX-U spherical torus and other magnetic fusion devices that employ molybdenum as plasma facing components.

  20. Imaging crystal spectrometer for high-resolution x-ray measurements on electron beam ion traps and tokamaks

    NASA Astrophysics Data System (ADS)

    Beiersdorfer, P.; Magee, E. W.; Hell, N.; Brown, G. V.

    2016-11-01

    We describe a crystal spectrometer implemented on the Livermore electron beam ion traps that employ two spherically bent quartz crystals and a cryogenically cooled back-illuminated charge-coupled device detector to measure x rays with a nominal resolving power of λ/Δλ ≥ 10 000. Its focusing properties allow us to record x rays either with the plane of dispersion perpendicular or parallel to the electron beam and, thus, to preferentially select one of the two linear x-ray polarization components. Moreover, by choice of dispersion plane and focussing conditions, we use the instrument either to image the distribution of the ions within the 2 cm long trap region, or to concentrate x rays of a given energy to a point on the detector, which optimizes the signal-to-noise ratio. We demonstrate the operation and utility of the new instrument by presenting spectra of Mo34+, which prepares the instrument for use as a core impurity diagnostic on the NSTX-U spherical torus and other magnetic fusion devices that employ molybdenum as plasma facing components.

  1. Heavy ion cocktail beams at the 88 inch Cyclotron

    SciTech Connect

    Leitner, Daniela; McMahan, Margaret A.; Argento, David; Gimpel, Thomas; Guy, Aran; Morel, James; Siero, Christine; Thatcher, Ray; Lyneis, Claude M.

    2002-09-03

    Cyclotrons in combination with ECR ion sources provide the ability to accelerate ''cocktails'' of ions. A cocktail is a mixture of ions of near-identical mass-to-charge (m/q) ratio. The different ions cannot be separated by the injector mass-analyzing magnet and are tuned out of the ion source together. The cyclotron then is utilized as a mass analyzer by shifting the accelerating frequency. This concept was developed soon after the first ECR ion source became operational at the 88-Inch Cyclotron and has since become a powerful tool in the field of heavy ion radiation effects testing. Several different ''cocktails'' at various energies are available at the 88-Inch cyclotron for radiation effect testing, covering a broad range of linear energy transfer and penetration depth. Two standard heavy ion cocktails at 4.5 MeV/nucleon and 10 MeV/nucleon have been developed over the years containing ions from boron to bismuth. Recently, following requests for higher penetration depths, a 15MeV/nucleon heavy ion cocktail has been developed. Up to nine different metal and gaseous ion beams at low to very high charge states are tuned out of the ion source simultaneously and injected together into the cyclotron. It is therefore crucial to balance the ion source very carefully to provide sufficient intensities throughout the cocktail. The paper describes the set-up and tuning of the ion source for the various heavy ion cocktails.

  2. Preliminary results from the heavy ions in space experiment

    NASA Technical Reports Server (NTRS)

    Adams, J. H., Jr.; Beahm, L. P.; Tylka, A. J.

    1991-01-01

    The Heavy Ions In Space (HIIS) experiment is intended to provide a deep survey of intensely ionizing particles in low earth orbit. Intensely ionizing particles produce single event effects in microelectronic components and are now recognized as the principal cause of spacecraft anomalies. These particles also make an important contribution to radiation doses. Besides the practical applications, HIIS data will be used to study several important scientific questions. By measuring heavy ions that stop in HIIS, the anomalous component of cosmic rays can be studied, evidence can be searched for of heavy ions trapped in the earth's magnetic field and by comparing HISS data with observations from outside the magnetosphere, the mean ionic charge state can be determined of solar energetic particles. HIIS will also record relativistic ultraheavy galactic cosmic rays. Their elemental composition will be measured from tin to uranium. Results are presented on the elemental resolution for stopping heavy ions and relativistic heavy ions.

  3. The Energetic Heavy Ion Sensor (EHIS) for GOES-R: Accelerator Calibrations of Flight Unit 1

    NASA Astrophysics Data System (ADS)

    Connell, J. J.; Lopate, C.

    2014-12-01

    The Energetic Heavy Ion Sensor (EHIS) instruments for GOES-R will provide high resolution measurement of energetic ions (Solar energetic particles and cosmic rays) from hydrogen (H) through nickel (Ni) for space weather monitoring and scientific research. Measurements are taken in five approximately logarithmically spaced energy intervals from 10-200 MeV/u for hydrogen and helium (He) and comparable penetrations for heavier elements. The Angle Detecting Inclined Sensors (ADIS) technique is used to provide single element resolution by determining the angle of incidence with a very simple telescope design using Si solid state detectors. The ADIS system also facilitates on-board event identification of ion species. During high flux conditions, EHIS can identify the elemental composition of ~2000 events per seconds. Elemental charge histograms are compiled on-board and reported via telemetry once per minute providing an unprecedented combination of statistical resolution and high cadence. The first of four flight instruments (FM1) has been completed. FM1 underwent heavy ion accelerator calibration at the National Superconducting Cyclotron Laboratory's (NSCL) Coupled Cyclotron Facility (CCF) at Michigan State University in February 2013, and proton calibration at the Massachusetts General Hospital's (MGH) Burr Proton Therapy Center in April 2013. The heavy ion calibration included both Ni primary and secondary fragments runs down to H. Results of these calibration runs will be presented.

  4. The Energetic Heavy Ion Sensor (EHIS) for GOES-R: Accelerator Calibrations of Flight Unit 1

    NASA Astrophysics Data System (ADS)

    Connell, J. J.; Lopate, C.

    2013-12-01

    The Energetic Heavy Ion Sensor (EHIS) instruments for GOES-R will provide high resolution measurement of energetic ions (Solar energetic particles and cosmic rays) from hydrogen (H) through nickel (Ni) for space weather monitoring and scientific research. Measurements are taken in five approximately logarithmically spaced energy intervals from 10-200 MeV/u for hydrogen and helium (He) and comparable penetrations for heavier elements. The Angle Detecting Inclined Sensors (ADIS) technique is used to provide single element resolution by determining the angle of incidence with a very simple telescope design using Si solid state detectors. The ADIS system also facilitates on-board event identification of ion species. During high flux conditions, EHIS can identify the elemental composition of ~2000 events per seconds. Elemental charge histograms are compiled on-board and reported via telemetry once per minute providing an unprecedented combination of statistical resolution and high cadence. The first of four flight instruments (FM1) has been completed. FM1 underwent heavy ion accelerator calibration at the National Superconducting Cyclotron Laboratory's (NSCL) Coupled Cyclotron Facility (CCF) at Michigan State University in February 2013 and proton calibration at the Massachusetts General Hospital's (MGH) Burr Proton Therapy Center in April 2013. The heavy ion calibration included both Ni primary and secondary fragments runs down to H. Results of these calibration runs will be presented. This work is supported by NASA under the contract NNG06HX01C.

  5. Heavy ion tracks in polycarbonate. Comparison with a heavy ion irradiated model compound (diphenyl carbonate)

    NASA Astrophysics Data System (ADS)

    Ferain, E.; Legras, R.

    1993-09-01

    The chemical modifications induced by energetic heavy ion irradiation of polycarbonate (PC) film are determined by GPC, HPLC, ESR, TGA, IR and UV spectrophotometry. The main results of the irradiation are creation of radicals, chain scission, cross-linking and appearance of new chemical groups in the main polymer chain. As far as the creation of new groups is concerned, they are determined by means of a model compound of PC: the diphenyl carbonate (DPC). The following compounds are identified after energetic heavy ion irradiation of DPC: salicylic acid, phenol, 4,4'-biphenol, 2,4'-biphenol, 2,2'-biphenol, 4-phenoxyphenol, 2-phenoxyphenol, phenyl ether, phenyl benzoate, phenyl salicylate, 2-phenylphenol and 2-phenoxyphenyl benzoate. A similarity between the heavy ion irradiation and a heat treatment has also been established with DPC. On the basis of these results, we try to give an explanation of the preferential attack along the tracks of the irradiated film. Also, an explanation of the well-known beneficial effect of an UV exposition of the irradiated film on the selectivity of this preferential chemical attack is suggested.

  6. Design status of heavy ion injector program

    SciTech Connect

    Ballard, E.O.; Meyer, E.A.; Riepe, K.B.; Rutkowski, H.L.; Shurter, R.P.; Van Haaften, F.W.

    1985-10-01

    Design and development of a sixteen beam, heavy ion injector is in progress at Los Alamos National Laboratory (LANL) to demonstrate the injector technology for the High Temperature Experiment (HTE) proposed by Lawrence Berkeley Laboratory. The injector design provides for individual ion sources mounted to a support plate defining the sixteen beam array. The beamlets are electrostatically accelerated through a series of electrodes inside an evacuated (10 X torr) high voltage (HV) accelerating column. The column consists of two 28-inch diameter insulator modules made of 85 percent Al2O3 ceramic rings brazed to niobium feedthrough rings to which the electrodes are mechanically attached. Field shaping is used to minimize electron avalanche induced flashover along the inside surface of the ceramic rings. The column is self-supporting and is cantilevered from one end of the containment vessel. A brazed assembly was chosen to provide the required bond strength and high vacuum capability. The HV pulsed power supply is a 2MV Marx generator cantilevered from the opposite end of the containment vessel. The stainless steel pressure vessel (PV) contains a 65 psig mixture of SF6(30%) and nitrogen (70%) to provide the electrical insulation.

  7. Structural Determination of Glycopeptidolipids of Mycobacterium smegmatis by High Resolution Multiple-stage Linear Ion-trap Mass Spectrometry with Electrospray Ionization

    PubMed Central

    Hsu, Fong-Fu; Pacheco, Sophia; Turk, John; Purdy, Georgiana

    2012-01-01

    Glycopeptidolipids (GPLs) are abundant in the cell walls of different species of mycobacteria and consist of tripeptide-amino-alcohol core of D-Phe-D-allo-Thr-D-Ala-L-alaninol linked to 3-hydroxy or 3-methoxy C26–34 fatty acyl chain at the N-terminal of D-Phe via amide linkage; and a 6-deoxytalose (6-dTal) and an O-methyl rhamnose residues respectively attach to D-allo-Thr and the terminal L-alaninol. They are important cell-surface antigens that are implicated in the pathogenesis of opportunistic mycobacteria belonging to the Mycobacterium avium complex. In this contribution, we described multiple-stage linear ion-trap in conjunction with high resolution mass spectrometry towards structural characterization of complex GPLs as [M + Na]+ ions isolated from Mycobacterium smegmatis, a fast-growing and non-pathogenic mycobacterial species. Following resonance excitation in an ion-trap, MSn spectra of the [M + Na]+ ions of GPLs contained mainly b and y series ions that readily determine the peptide sequence. Fragment ions from MSn also afford locating the 6-dTal and O-methyl rhamnose residues linked to the D-allo-Thr and terminal L-alaninol of the peptide core, respectively, as well as recognizing the modifications of the glycosides, including their acetylation and methylation states and the presence of succinyl group. The GPL families consisting of 3-hydroxy fatty acyl and of 3-methoxy fatty acyl substituents are readily distinguishable. The MS profiles of the GPLs from cells are dependant on the conditions they were grown and several isobaric isomers were identified for many of the molecular species. These multiple-stage mass spectrometric approaches give detailed structures of GPL in complex mixtures of which the isomeric structures are difficult to define using other analytical methods. PMID:23019158

  8. Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cells

    PubMed Central

    Miragoli, Michele; Moshkov, Alexey; Novak, Pavel; Shevchuk, Andrew; Nikolaev, Viacheslav O.; El-Hamamsy, Ismail; Potter, Claire M. F.; Wright, Peter; Kadir, S.H. Sheikh Abdul; Lyon, Alexander R.; Mitchell, Jane A.; Chester, Adrian H.; Klenerman, David; Lab, Max J.; Korchev, Yuri E.; Harding, Sian E.; Gorelik, Julia

    2011-01-01

    Cardiovascular diseases are complex pathologies that include alterations of various cell functions at the levels of intact tissue, single cells and subcellular signalling compartments. Conventional techniques to study these processes are extremely divergent and rely on a combination of individual methods, which usually provide spatially and temporally limited information on single parameters of interest. This review describes scanning ion conductance microscopy (SICM) as a novel versatile technique capable of simultaneously reporting various structural and functional parameters at nanometre resolution in living cardiovascular cells at the level of the whole tissue, single cells and at the subcellular level, to investigate the mechanisms of cardiovascular disease. SICM is a multimodal imaging technology that allows concurrent and dynamic analysis of membrane morphology and various functional parameters (cell volume, membrane potentials, cellular contraction, single ion-channel currents and some parameters of intracellular signalling) in intact living cardiovascular cells and tissues with nanometre resolution at different levels of organization (tissue, cellular and subcellular levels). Using this technique, we showed that at the tissue level, cell orientation in the inner and outer aortic arch distinguishes atheroprone and atheroprotected regions. At the cellular level, heart failure leads to a pronounced loss of T-tubules in cardiac myocytes accompanied by a reduction in Z-groove ratio. We also demonstrated the capability of SICM to measure the entire cell volume as an index of cellular hypertrophy. This method can be further combined with fluorescence to simultaneously measure cardiomyocyte contraction and intracellular calcium transients or to map subcellular localization of membrane receptors coupled to cyclic adenosine monophosphate production. The SICM pipette can be used for patch-clamp recordings of membrane potential and single channel currents. In

  9. Direct infusion electrospray ionization-ion mobility high resolution mass spectrometry (DIESI-IM-HRMS) for rapid characterization of potential bioprocess streams.

    PubMed

    Munisamy, Sharon M; Chambliss, C Kevin; Becker, Christopher

    2012-07-01

    Direct infusion electrospray ionization - ion mobility - high resolution mass spectrometry (DIESI-IM-HRMS) has been utilized as a rapid technique for the characterization of total molecular composition in "whole-sample" biomass hydrolysates and extracts. IM-HRMS data reveal a broad molecular weight distribution of sample components (up to 1100 m/z) and provide trendline isolation of feedstock components from those introduced "in process." Chemical formulas were obtained from HRMS exact mass measurements (with typical mass error less than 5 ppm) and were consistent with structural carbohydrates and other lignocellulosic degradation products. Analyte assignments are supported via IM-MS collision-cross-section measurements and trendline analysis (e.g., all carbohydrate oligomers identified in a corn stover hydrolysate were found to fall within 6% of an average trendline). These data represent the first report of collision cross sections for several negatively charged carbohydrates and other acidic species occurring natively in biomass hydrolysates.

  10. Determination of testosterone in plasma from men by gas chromatography/mass spectrometry, with high-resolution selected-ion monitoring and metastable peak monitoring

    SciTech Connect

    Finlay, E.M.; Gaskell, S.J.

    1981-07-01

    Highly specific methods are described for determining testosterone in plasma or serum from men. Extract fractions obtained by selective isolation procedures are converted to tert-butyldimethylsilyl (TBDMS) oximes/TBDMS ethers or methyl oximes/TBDMS ethers and analyzed by gas chromatography/mass spectrometry in the high-resolution selected-ion monitoring or metastable peak-monitoring modes. (2H3)Testosterone and unlabeled 17-epitestosterone are used as the respective internal standards. When we applied the two procedures to analysis of samples of pooled plasma and serum used for external quality assessment of routine assays, the results agreed well. Interlaboratory values for mean concentrations obtained by routine immunoassays (y) consistently exceeded values obtained by our technique (x), although the values closely correlated (r . 0.997; y . 1.008x + 0.564 nmol/L).

  11. Ne{sup +} ion sputtering effect on amorphous Ga-In-Zn-O thin-film surface investigated by high-resolution XPS

    SciTech Connect

    Kang, Se-Jun; Lee, Mi Ji; Baik, Jae Yoon; Kim, Hyeong-Do; Thakur, Anup; Shin, Hyun-Joon; Chung, JaeGwan; Lee, Eunha; Lee, Jaecheol; Lee, JaeHak

    2011-12-23

    The effect of Ne{sup +} ion sputtering on amorphous Ga-In-Zn-O (a-GIZO) thin films was investigated by using surface-sensitive, synchrotron-radiation-based, high-resolution X-ray photoelectron spectroscopy (XPS). a-GIZO thin films having different compositions (Ga{sub 2}O{sub 3}:In{sub 2}O{sub 3}:ZnO = 1:1:1, 2:2:1, 3:2:1, 4:2:1) were investigated. It was found out that the amounts of the In and Zn contents relative to that of Ga decreased noticeably after sufficient sputtering, and that there occurred a subgap state above the valence band maximum and metallic states at the In 3d and 4d core levels as well as at the Fermi edge.

  12. High-resolution structure of the N-terminal endonuclease domain of the Lassa virus L polymerase in complex with magnesium ions.

    PubMed

    Wallat, Gregor D; Huang, Qinfeng; Wang, Wenjian; Dong, Haohao; Ly, Hinh; Liang, Yuying; Dong, Changjiang

    2014-01-01

    Lassa virus (LASV) causes deadly hemorrhagic fever disease for which there are no vaccines and limited treatments. LASV-encoded L polymerase is required for viral RNA replication and transcription. The functional domains of L-a large protein of 2218 amino acid residues-are largely undefined, except for the centrally located RNA-dependent RNA polymerase (RdRP) motif. Recent structural and functional analyses of the N-terminal region of the L protein from lymphocytic choriomeningitis virus (LCMV), which is in the same Arenaviridae family as LASV, have identified an endonuclease domain that presumably cleaves the cap structures of host mRNAs in order to initiate viral transcription. Here we present a high-resolution crystal structure of the N-terminal 173-aa region of the LASV L protein (LASV L173) in complex with magnesium ions at 1.72 Å. The structure is highly homologous to other known viral endonucleases of arena- (LCMV NL1), orthomyxo- (influenza virus PA), and bunyaviruses (La Crosse virus NL1). Although the catalytic residues (D89, E102 and K122) are highly conserved among the known viral endonucleases, LASV L endonuclease structure shows some notable differences. Our data collected from in vitro endonuclease assays and a reporter-based LASV minigenome transcriptional assay in mammalian cells confirm structural prediction of LASV L173 as an active endonuclease. The high-resolution structure of the LASV L endonuclease domain in complex with magnesium ions should aid the development of antivirals against lethal Lassa hemorrhagic fever.

  13. Conformational Ordering of Biomolecules in the Gas Phase: Nitrogen Collision Cross Sections Measured on a Prototype High Resolution Drift Tube Ion Mobility-Mass Spectrometer

    PubMed Central

    2014-01-01

    Ion mobility-mass spectrometry measurements which describe the gas-phase scaling of molecular size and mass are of both fundamental and pragmatic utility. Fundamentally, such measurements expand our understanding of intrinsic intramolecular folding forces in the absence of solvent. Practically, reproducible transport properties, such as gas-phase collision cross-section (CCS), are analytically useful metrics for identification and characterization purposes. Here, we report 594 CCS values obtained in nitrogen drift gas on an electrostatic drift tube ion mobility-mass spectrometry (IM-MS) instrument. The instrument platform is a newly developed prototype incorporating a uniform-field drift tube bracketed by electrodynamic ion funnels and coupled to a high resolution quadrupole time-of-flight mass spectrometer. The CCS values reported here are of high experimental precision (±0.5% or better) and represent four chemically distinct classes of molecules (quaternary ammonium salts, lipids, peptides, and carbohydrates), which enables structural comparisons to be made between molecules of different chemical compositions for the rapid “omni-omic” characterization of complex biological samples. Comparisons made between helium and nitrogen-derived CCS measurements demonstrate that nitrogen CCS values are systematically larger than helium values; however, general separation trends between chemical classes are retained regardless of the drift gas. These results underscore that, for the highest CCS accuracy, care must be exercised when utilizing helium-derived CCS values to calibrate measurements obtained in nitrogen, as is the common practice in the field. PMID:24446877

  14. Conformational ordering of biomolecules in the gas phase: nitrogen collision cross sections measured on a prototype high resolution drift tube ion mobility-mass spectrometer.

    PubMed

    May, Jody C; Goodwin, Cody R; Lareau, Nichole M; Leaptrot, Katrina L; Morris, Caleb B; Kurulugama, Ruwan T; Mordehai, Alex; Klein, Christian; Barry, William; Darland, Ed; Overney, Gregor; Imatani, Kenneth; Stafford, George C; Fjeldsted, John C; McLean, John A

    2014-02-18

    Ion mobility-mass spectrometry measurements which describe the gas-phase scaling of molecular size and mass are of both fundamental and pragmatic utility. Fundamentally, such measurements expand our understanding of intrinsic intramolecular folding forces in the absence of solvent. Practically, reproducible transport properties, such as gas-phase collision cross-section (CCS), are analytically useful metrics for identification and characterization purposes. Here, we report 594 CCS values obtained in nitrogen drift gas on an electrostatic drift tube ion mobility-mass spectrometry (IM-MS) instrument. The instrument platform is a newly developed prototype incorporating a uniform-field drift tube bracketed by electrodynamic ion funnels and coupled to a high resolution quadrupole time-of-flight mass spectrometer. The CCS values reported here are of high experimental precision (±0.5% or better) and represent four chemically distinct classes of molecules (quaternary ammonium salts, lipids, peptides, and carbohydrates), which enables structural comparisons to be made between molecules of different chemical compositions for the rapid "omni-omic" characterization of complex biological samples. Comparisons made between helium and nitrogen-derived CCS measurements demonstrate that nitrogen CCS values are systematically larger than helium values; however, general separation trends between chemical classes are retained regardless of the drift gas. These results underscore that, for the highest CCS accuracy, care must be exercised when utilizing helium-derived CCS values to calibrate measurements obtained in nitrogen, as is the common practice in the field.

  15. Organic solvent and temperature-enhanced ion chromatography-high resolution mass spectrometry for the determination of low molecular weight organic and inorganic anions.

    PubMed

    Gilchrist, Elizabeth S; Nesterenko, Pavel N; Smith, Norman W; Barron, Leon P

    2015-03-20

    There has recently been increased interest in coupling ion chromatography (IC) to high resolution mass spectrometry (HRMS) to enable highly sensitive and selective analysis. Herein, the first comprehensive study focusing on the direct coupling of suppressed IC to HRMS without the need for post-suppressor organic solvent modification is presented. Chromatographic selectivity and added HRMS sensitivity offered by organic solvent-modified IC eluents on a modern hyper-crosslinked polymeric anion-exchange resin (IonPac AS18) are shown using isocratic eluents containing 5-50 mM hydroxide with 0-80% methanol or acetonitrile for a range of low molecular weight anions (<165 Da). Comprehensive experiments on IC thermodynamics over a temperature range between 20-45 °C with the eluent containing up to 60% of acetonitrile or methanol revealed markedly different retention behaviour and selectivity for the selected analytes on the same polymer based ion-exchange resin. Optimised sensitivity with HRMS was achieved with as low as 30-40% organic eluent content. Analytical performance characteristics are presented and compared with other IC-MS based works. This study also presents the first application of IC-HRMS to forensic detection of trace low-order anionic explosive residues in latent human fingermarks.

  16. [Screening and confirmation of 24 hormones in cosmetics by ultra high performance liquid chromatography-linear ion trap/orbitrap high resolution mass spectrometry].

    PubMed

    Li, Zhaoyong; Wang, Fengmei; Niu, Zengyuan; Luo, Xin; Zhang, Gang; Chen, Junhui

    2014-05-01

    A method of ultra high performance liquid chromatography-linear ion trap/orbitrap high resolution mass spectrometry (UPLC-LTQ/Orbitrap MS) was established to screen and confirm 24 hormones in cosmetics. Various cosmetic samples were extracted with methanol. The extract was loaded onto a Waters ACQUITY UPLC BEH C18 column (50 mm x 2.1 mm, 1.7 microm) using a gradient elution of acetonitrile/water containing 0.1% (v/v) formic acid for the separation. The accurate mass of quasi-molecular ion was acquired by full scanning of electrostatic field orbitrap. The rapid screening was carried out by the accurate mass of quasi-molecular ion. The confirmation analysis for targeted compounds was performed with the retention time and qualitative fragments obtained by data dependent scan mode. Under the optimal conditions, the 24 hormones were routinely detected with mass accuracy error below 3 x 10(-6) (3 ppm), and good linearities were obtained in their respective linear ranges with correlation coefficients higher than 0.99. The LODs (S/N = 3) of the 24 compounds were < or = 10 microg/kg, which can meet the requirements for the actual screening of cosmetic samples. The developed method was applied to screen the hormones in 50 cosmetic samples. The results demonstrate that the method is a useful tool for the rapid screening and identification of the hormones in cosmetics.

  17. Validation of a pH gradient-based ion-exchange chromatography method for high-resolution monoclonal antibody charge variant separations.

    PubMed

    Rea, Jennifer C; Moreno, G Tony; Lou, Yun; Farnan, Dell

    2011-01-25

    Ion-exchange chromatography is widely used for profiling the charge heterogeneity of proteins, including monoclonal antibodies. Despite good resolving power and robustness, ionic strength-based ion-exchange separations are product-specific and time-consuming to develop. We have previously reported a novel pH-based separation of proteins by cation exchange chromatography that was multi-product, high-resolution, and robust against variations in sample matrix salt concentration and pH. In this study, a pH gradient-based separation method using cation exchange chromatography was evaluated in a mock validation. This method was shown to be robust for monoclonal antibodies and suitable for its intended purpose of charge heterogeneity analysis. Simple mixtures of defined buffer components were used to generate the pH gradients that separated closely related antibody species. Validation characteristics, such as precision and linearity, were evaluated. Robustness to changes in protein load, buffer pH and column oven temperature was demonstrated. The stability-indicating capability of this method was determined using thermally stressed antibody samples. In addition, intermediate precision was demonstrated using multiple instruments, multiple analysts, multiple column lots, and different column manufacturers. Finally, the precision for this method was compared to conventional ion-exchange chromatography and imaged capillary isoelectric focusing. These results demonstrate the superior precision and robustness of this multi-product method, which can be used for the high-throughput evaluation of in-process and final product samples.

  18. Heavy ion induced permanent damage in MNOS gate insulators

    NASA Astrophysics Data System (ADS)

    Pickel, J. C.; Blandford, J. T., Jr.; Waskiewicz, A. E.; Strahan, V. H., Jr.

    1985-12-01

    Heavy-ion-induced permanent damage in MNOS gate insulators has been investigated using a Cf252 fission source. The electric field and ion LET thresholds for onset of the damage has been characterized. The results are consistent with a thermal runaway mechanism in the silicon nitride layer initiated by a single heavy ion and leading to a permanent high conductivity path through the dielectric layers.

  19. Optical methods for the detection of heavy metal ions

    NASA Astrophysics Data System (ADS)

    Uglov, A. N.; Bessmertnykh-Lemeune, A.; Guilard, R.; Averin, A. D.; Beletskaya, I. P.

    2014-03-01

    The review covers an important area of the modern chemistry, namely, the detection of heavy metal ions using optical molecular detectors. The role of this method in metal ion detection and the physicochemical grounds of operation of chemosensors are discussed, and examples of detection of most abundant heavy metal ions and synthetic approaches to molecular detectors are presented. The immobilization of molecular detectors on solid substrates for the design of analytical sensor devices is described. The bibliography includes 178 references.

  20. HIGH-INTENSITY, HIGH CHARGE-STATE HEAVY ION SOURCES

    SciTech Connect

    ALESSI,J.G.

    2004-08-16

    There are many accelerator applications for high intensity heavy ion sources, with recent needs including dc beams for RIA, and pulsed beams for injection into synchrotrons such as RHIC and LHC. The present status of sources producing high currents of high charge state heavy ions is reviewed. These sources include ECR, EBIS, and Laser ion sources. Benefits and limitations for these type sources are described. Possible future improvements in these sources are also mentioned.

  1. Plasma Beta Dependence of the Ion-scale Spectral Break of Solar Wind Turbulence: High-resolution 2D Hybrid Simulations

    NASA Astrophysics Data System (ADS)

    Franci, Luca; Landi, Simone; Matteini, Lorenzo; Verdini, Andrea; Hellinger, Petr

    2016-12-01

    We investigate properties of the ion-scale spectral break of solar wind turbulence by means of two-dimensional high-resolution hybrid particle-in-cell simulations. We impose an initial ambient magnetic field perpendicular to the simulation box and add a spectrum of in-plane, large-scale, magnetic and kinetic fluctuations. We perform a set of simulations with different values of the plasma β, distributed over three orders of magnitude, from 0.01 to 10. In all cases, once turbulence is fully developed, we observe a power-law spectrum of the fluctuating magnetic field on large scales (in the inertial range) with a spectral index close to -5/3, while in the sub-ion range we observe another power-law spectrum with a spectral index systematically varying with β (from around -3.6 for small values to around -2.9 for large ones). The two ranges are separated by a spectral break around ion scales. The length scale at which this transition occurs is found to be proportional to the ion inertial length, d i , for β ≪ 1 and to the ion gyroradius, {ρ }i={d}i\\sqrt{β }, for β ≫ 1, i.e., to the larger between the two scales in both the extreme regimes. For intermediate cases, i.e., β ˜ 1, a combination of the two scales is involved. We infer an empiric relation for the dependency of the spectral break on β that provides a good fit over the whole range of values. We compare our results with in situ observations in the solar wind and suggest possible explanations for such a behavior.

  2. Skyrme tensor force in heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Stevenson, P. D.; Suckling, E. B.; Fracasso, S.; Barton, M. C.; Umar, A. S.

    2016-05-01

    Background: It is generally acknowledged that the time-dependent Hartree-Fock (TDHF) method provides a useful foundation for a fully microscopic many-body theory of low-energy heavy ion reactions. The TDHF method is also known in nuclear physics in the small-amplitude domain, where it provides a useful description of collective states, and is based on the mean-field formalism, which has been a relatively successful approximation to the nuclear many-body problem. Currently, the TDHF theory is being widely used in the study of fusion excitation functions, fission, and deep-inelastic scattering of heavy mass systems, while providing a natural foundation for many other studies. Purpose: With the advancement of computational power it is now possible to undertake TDHF calculations without any symmetry assumptions and incorporate the major strides made by the nuclear structure community in improving the energy density functionals used in these calculations. In particular, time-odd and tensor terms in these functionals are naturally present during the dynamical evolution, while being absent or minimally important for most static calculations. The parameters of these terms are determined by the requirement of Galilean invariance or local gauge invariance but their significance for the reaction dynamics have not been fully studied. This work addresses this question with emphasis on the tensor force. Method: The full version of the Skyrme force, including terms arising only from the Skyrme tensor force, is applied to the study of collisions within a completely symmetry-unrestricted TDHF implementation. Results: We examine the effect on upper fusion thresholds with and without the tensor force terms and find an effect on the fusion threshold energy of the order several MeV. Details of the distribution of the energy within terms in the energy density functional are also discussed. Conclusions: Terms in the energy density functional linked to the tensor force can play a non

  3. Heavy-ion collisions at the LHC

    NASA Astrophysics Data System (ADS)

    Roland, G.; Šafařík, K.; Steinberg, P.

    2014-07-01

    A new era in the study of high-energy nuclear collisions began when the CERN Large Hadron Collider (LHC) provided the first collisions of lead nuclei in late 2010. In the first three years of operation the ALICE, ATLAS and CMS experiments each collected Pb-Pb data samples of more than 50 μb at √{sNN}=2.76 TeV, exceeding the previously studied collision energies by more than an order of magnitude. These data have provided new insights into the properties of QCD matter under extreme conditions, with extensive measurements of soft particle production and newly accessible hard probes of the hot and dense medium. In this review, we provide a comprehensive overview of the results obtained in heavy-ion collisions at the LHC so far, with particular emphasis on the complementary nature of the observations by the three experiments. In particular, the combination of ALICE’s strengths at hadron identification, the strengths of ATLAS and CMS to make precise measurements of high pT probes, and the resourceful measurements of collective flow by all of the experiments have provided a rich and diverse dataset in only a few years. While the basic paradigm established at RHIC - that of a hot, dense medium that flows with a viscosity to shear-entropy ratio near the predicted lower bound, and which degrades the energy of probes, such as jets, heavy-flavours and J/ψ - is confirmed at the LHC, the new data suggest many new avenues for extracting its properties in detail.

  4. Heavy-flavour productions in the relativistic heavy ion collisions in LHC

    NASA Astrophysics Data System (ADS)

    Sakai, Shingo

    2017-03-01

    In the Large Hadron Collider (LHC), open heavy-flavour productions in the heavy-ion collisions (Pb-Pb) has studied by measuring D mesons, leptons from semi-leptonic decay of heavy-flavour hadrons and jets which are original from heavy quarks. In this proceedings, those results are shown together with the measurements with pp and p-Pb collisions and discussed with theoretical calculations to understand the properties of the QCD matter.

  5. Design study of primary ion provider for relativistic heavy ion collider electron beam ion source.

    PubMed

    Kondo, K; Kanesue, T; Tamura, J; Okamura, M

    2010-02-01

    Brookhaven National Laboratory has developed the new preinjector system, electron beam ion source (EBIS) for relativistic heavy ion collider (RHIC) and National Aeronautics and Space Administration Space Radiation Laboratory. Design of primary ion provider is an essential problem since it is required to supply beams with different ion species to multiple users simultaneously. The laser ion source with a defocused laser can provide a low charge state and low emittance ion beam, and is a candidate for the primary ion source for RHIC-EBIS. We show a suitable design with appropriate drift length and solenoid, which helps to keep sufficient total charge number with longer pulse length. The whole design of primary ion source, as well as optics arrangement, solid targets configuration and heating about target, is presented.

  6. Experimental Evaluation of a Negative Ion Source for a Heavy Ion Fusion Negative Ion Driver

    SciTech Connect

    Grisham, L. R.; Hahto, S. K.; Hahto, S. T.; Kwan, J. W.; Leung, K. N.

    2004-06-16

    Negative halogen ions have recently been proposed as a possible alternative to positive ions for heavy ion fusion drivers because electron accumulation would not be a problem in the accelerator, and if desired, the beams could be photo-detached to neutrals. To test the ability to make suitable quality beams, an experiment was conducted at Lawrence Berkeley National Laboratory using chlorine in an RF-driven ion source. Without introducing any cesium (which is required to enhance negative ion production in hydrogen ion sources) a negative chlorine current density of 45 mA/cm{sup 2} was obtained under the same conditions that gave 57 45 mA/cm{sup 2} of positive chlorine, suggesting the presence of nearly as many negative ions as positive ions in the plasma near the extraction plane. The negative ion spectrum was 99.5% atomic chlorine ions, with only 0.5% molecular chlorine, and essentially no impurities. Although this experiment did not incorporate the type of electron suppression technology that i s used in negative hydrogen beam extraction, the ratio of co-extracted electrons to Cl{sup -} was as low as 7 to 1, many times lower than the ratio of their mobilities, suggesting that few electrons are present in the near-extractor plasma. This, along with the near-equivalence of the positive and negative ion currents, suggests that the plasma in this region was mostly an ion-ion plasma. The negative chlorine current density was relatively insensitive to pressure, and scaled linearly with RF power. If this linear scaling continues to hold at higher RF powers, it should permit current densities of 100 45 mA/cm{sup 2}, sufficient for present heavy ion fusion injector concepts. The effective ion temperatures of the positive and negative ions appeared to be similar and relatively low for a plasma source.

  7. Ion sources for induction linac driven heavy ion fusion

    SciTech Connect

    Rutkowski, H.L.; Eylon, S.; Chupp, W.W.

    1993-08-01

    The use of ion sources in induction linacs for heavy ion fusion is fundamentally different from their use in the rf linac-storage rings approach. Induction linacs require very high current, short pulse extraction usually with large apertures which are dictated by the injector design. One is faced with the problem of extracting beams in a pulsed fashion while maintaining high beam quality during the pulse (low-emittance). Four types of sources have been studied for this application. The vacuum arc and the rf cusp field source are the plasma types and the porous plug and hot alumino-silicate surface source are the thermal types. The hot alumino-silicate potassium source has proved to be the best candidate for the next generation of scaled experiments. The porous plug for potassium is somewhat more difficult to use. The vacuum arc suffers from noise and lifetime problems and the rf cusp field source is difficult to use with very short pulses. Operational experience with all of these types of sources is presented.

  8. Review on heavy ion radiotherapy facilities and related ion sources (invited)a)

    NASA Astrophysics Data System (ADS)

    Kitagawa, A.; Fujita, T.; Muramatsu, M.; Biri, S.; Drentje, A. G.

    2010-02-01

    Heavy ion radiotherapy awakens worldwide interest recently. The clinical results obtained by the Heavy Ion Medical Accelerator in Chiba at the National Institute of Radiological Sciences in Japan have clearly demonstrated the advantages of carbon ion radiotherapy. Presently, there are four facilities for heavy ion radiotherapy in operation, and several new facilities are under construction or being planned. The most common requests for ion sources are a long lifetime and good stability and reproducibility. Sufficient intensity has been achieved by electron cyclotron resonance ion sources at the present facilities.

  9. Review on heavy ion radiotherapy facilities and related ion sources (invited)

    SciTech Connect

    Kitagawa, A.; Fujita, T.; Muramatsu, M.; Biri, S.

    2010-02-15

    Heavy ion radiotherapy awakens worldwide interest recently. The clinical results obtained by the Heavy Ion Medical Accelerator in Chiba at the National Institute of Radiological Sciences in Japan have clearly demonstrated the advantages of carbon ion radiotherapy. Presently, there are four facilities for heavy ion radiotherapy in operation, and several new facilities are under construction or being planned. The most common requests for ion sources are a long lifetime and good stability and reproducibility. Sufficient intensity has been achieved by electron cyclotron resonance ion sources at the present facilities.

  10. Equilibration and multifragmentation in heavy ion reactions

    SciTech Connect

    Peilert, G.; Mustafa, M.G.; Blann, M.; Botvina, A.

    1993-09-01

    Modeling of multifragmentation measurements from heavy ion reactions generally requires separate treatment of the initial fast part of the reaction, during which energetic nucleons are emitted, and of a quasi-equilibrated system where sufficient degrees of freedom have been excited, so that statistical approaches may be applied. Some of the more sophisticated fast cascade models, e.g., Quantum molecular dynamics (QMD), might also produce fragment yields, however, transport models have not yet been able to satisfactorily reproduce fragmentation properties of nuclear reactions. In this work we consider the interactions of {sup 36}Ar with {sup 197}Au at incident energies of 35 to 110 MeV{center_dot}A, which was investigated by de Souza et al. We will first look at two dynamic models which may be used to estimate the excitation remaining for quasi-equilibrated systems following the fast nucleonic cascade, specifically the Boltzmann master equation (BME) and Quantum molecular dynamics (QMD) approaches. Using excitations from the BME model to estimate values for quasi-equilibrated nuclei, we will explore two approaches to statistical multifragmentation calculations, one of sequential binary decay, the other a simultaneous multifragmentation model (SMM). We will consider central collisions in our calculations, and experimental results gated on the highest total charged particle emissions -- those deduced to be central collisions.

  11. Inertially confined fusion using heavy ion drivers

    SciTech Connect

    Herrmannsfeldt, W.B. ); Bangerter, R.O. ); Bock, R. ); Hogan, W.J.; Lindl, J.D. )

    1991-10-01

    The various technical issues of HIF will be briefly reviewed in this paper. It will be seen that there are numerous areas in common in all the approaches to HIF. In the recent International Symposium on Heavy Ion Inertial Fusion, the attendees met in specialized workshop sessions to consider the needs for research in each area. Each of the workshop groups considered the key questions of this report: (1) Is this an appropriate time for international collaboration in HIF (2) Which problems are most appropriate for such collaboration (3) Can the sharing of target design information be set aside until other driver and systems issues are better resolved, by which time it might be supposed that there could be a relaxation of classification of target issues (4) What form(s) of collaboration are most appropriate, e.g., bilateral or multilateral (5) Can international collaboration be sensibly attempted without significant increases in funding for HIF The authors of this report share the conviction that collaboration on a broad scale is mandatory for HIF to have the resources, both financial and personnel, to progress to a demonstration experiment. Ultimately it may be possible for a single driver with the energy, power, focusibility, and pulse shape to satisfy the needs of the international community for target physics research. Such a facility could service multiple experimental chambers with a variety of beam geometries and target concepts.

  12. Inertially confined fusion using heavy ion drivers

    SciTech Connect

    Herrmannsfeldt, W.B.; Bangerter, R.O.; Bock, R.; Hogan, W.J.; Lindl, J.D.

    1991-10-01

    The various technical issues of HIF will be briefly reviewed in this paper. It will be seen that there are numerous areas in common in all the approaches to HIF. In the recent International Symposium on Heavy Ion Inertial Fusion, the attendees met in specialized workshop sessions to consider the needs for research in each area. Each of the workshop groups considered the key questions of this report: (1) Is this an appropriate time for international collaboration in HIF? (2) Which problems are most appropriate for such collaboration? (3) Can the sharing of target design information be set aside until other driver and systems issues are better resolved, by which time it might be supposed that there could be a relaxation of classification of target issues? (4) What form(s) of collaboration are most appropriate, e.g., bilateral or multilateral? (5) Can international collaboration be sensibly attempted without significant increases in funding for HIF? The authors of this report share the conviction that collaboration on a broad scale is mandatory for HIF to have the resources, both financial and personnel, to progress to a demonstration experiment. Ultimately it may be possible for a single driver with the energy, power, focusibility, and pulse shape to satisfy the needs of the international community for target physics research. Such a facility could service multiple experimental chambers with a variety of beam geometries and target concepts.

  13. New results for ultraperipheral heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Szczurek, Antoni; Kłusek-Gawenda, Mariola; Lebiedowicz, Piotr; Schäfer, Wolfgang

    2017-03-01

    We discuss diphoton semi(exclusive) production in ultraperipheral PbPb collisions at energy of √{sN N }=5.5 TeV (LHC). The nuclear calculations are based on equivalent photon approximation in the impact parameter space. The cross sections for elementary γγ → γγ subprocess are calculated including three different mechanisms: box diagrams with leptons and quarks in the loops, a VDM-Regge contribution with virtual intermediate hadronic excitations of the photons and the two-gluon exchange contribution (formally three-loops). We got relatively high cross sections in PbPb collisions. This opens a possibility to study the γγ → γγ (quasi)elastic scattering at the LHC. We find that the cross section for elastic γγ scattering could be measured in the lead-lead collisions for the diphoton invariant mass up to Wγγ ≈ 15 - 20 GeV. We identify region(s) of phase space where the two-gluon exchange contribution becomes important ingredient compared to box and nonperturbative VDM-Regge mechanisms. We discuss also first results concerning production of two e+e- pairs in UPCs of heavy ions. We considered only double scattering mechanism.

  14. Strange Particles and Heavy Ion Physics

    SciTech Connect

    Bassalleck, Bernd; Fields, Douglas

    2016-04-28

    This very long-running grant has supported many experiments in nuclear and particle physics by a group from the University of New Mexico. The gamut of these experiments runs from many aspects of Strangeness Nuclear Physics, to rare Kaon decays, to searches for exotic Hadrons such as Pentaquark or H-Dibaryon, and finally to Spin Physics within the PHENIX collaboration at RHIC. These experiments were performed at a number of laboratories worldwide: first and foremost at Brookhaven National Lab (BNL), but also at CERN, KEK, and most recently at J-PARC. In this Final Technical Report we summarize progress and achievements for this award since our last Progress Report, i.e. for the period of fall 2013 until the award’s termination on November 30, 2015. The report consists of two parts, representing our two most recent experimental efforts, participation in the Nucleon Spin Physics program of the PHENIX experiment at RHIC, the Relativistic Heavy Ion Collider at BNL – Task 1, led by Douglas Fields; and participation in several Strangeness Nuclear Physics experiments at J-PARC, the Japan Proton Accelerator Research Center in Tokai-mura, Japan – Task 2, led by Bernd Bassalleck.

  15. Heavy ion fusion: Prospects and status

    SciTech Connect

    Herrmannsfeldt, W.B.

    1995-10-01

    The main purpose of this talk is to review the status of HIF as it was presented at Princeton, and also to try to deduce something about the prospects for HIF in particular, and fusion in general, from the world and US political scene. The status of the field is largely, though not entirely, expressed through presentations from the two leading HIF efforts: (1) the US program, centered at LBNL and LLNL, is primarily concerned with applying induction linac technology for HIF drivers; (2) the European program, centered at GSI, Darmstadt, but including several other laboratories, is primarily directed towards the rf linac approach using storage rings for energy compression. Several developments in the field of HIF should be noted: (1) progress towards construction of the National Ignition Facility (NIF) gives strength to the whole rational for developing a driver for Inertial Fusion Energy; (2) the field of accelerator science has matured far beyond the status that it had in 1976; (3) Heavy Ion Fusion has passed some more reviews, including one by the Fusion Energy Advisory Committee (FEAC), and has received the usual good marks; (5) as the budgets for Magnetic Fusion have fallen, the pressures on the Office of Fusion energy (OFE) have intensified, and a move is underway to shift the HIF program out of the IFE program and back into the ICF program in the Defense Programs (DP) side of the DOE.

  16. Pre-equilibrium decay processes in energetic heavy ion reactions

    SciTech Connect

    Blann, M.

    1986-04-15

    The Boltzmann master equation (BME) is defined for application to precompound decay in heavy ion reactions in the 10 100 MeV/nucleon regime. Predicted neutron spectra are compared with measured results for central collisions of /sup 20/Ne and /sup 12/C with /sup 165/Ho target nuclei. Comparisons are made with subthreshold ..pi../sup 0/ yields in heavy ion reactions between 35 and 84 MeV/nucleon, and with the ..pi../sup 0/ spectra. The BME is found to be an excellent tool for investigating these experimentally observed aspects of non-equilibrium heavy ion reactions. 18 refs., 8 figs.

  17. Model for Cumulative Solar Heavy Ion Energy and LET Spectra

    NASA Technical Reports Server (NTRS)

    Xapsos, Mike; Barth, Janet; Stauffer, Craig; Jordan, Tom; Mewaldt, Richard

    2007-01-01

    A probabilistic model of cumulative solar heavy ion energy and lineary energy transfer (LET) spectra is developed for spacecraft design applications. Spectra are given as a function of confidence level, mission time period during solar maximum and shielding thickness. It is shown that long-term solar heavy ion fluxes exceed galactic cosmic ray fluxes during solar maximum for shielding levels of interest. Cumulative solar heavy ion fluences should therefore be accounted for in single event effects rate calculations and in the planning of space missions.

  18. Benchmarking of Neutron Production of Heavy-Ion Transport Codes

    SciTech Connect

    Remec, Igor; Ronningen, Reginald M.; Heilbronn, Lawrence

    2012-01-01

    Accurate prediction of radiation fields generated by heavy ion interactions is important in medical applications, space missions, and in design and operation of rare isotope research facilities. In recent years, several well-established computer codes in widespread use for particle and radiation transport calculations have been equipped with the capability to simulate heavy ion transport and interactions. To assess and validate these capabilities, we performed simulations of a series of benchmark-quality heavy ion experiments with the computer codes FLUKA, MARS15, MCNPX, and PHITS. We focus on the comparisons of secondary neutron production. Results are encouraging; however, further improvements in models and codes and additional benchmarking are required.

  19. Identification of novel non-ionic, cationic, zwitterionic, and anionic polyfluoroalkyl substances using UPLC-TOF-MS(E) high-resolution parent ion search.

    PubMed

    Xiao, Feng; Golovko, Svetlana A; Golovko, Mikhail Y

    2017-10-02

    Poly- and perfluoroalkyl substances (poly- and per-PFASs) are a large group of organic compounds that have become the target of investigation due to their widespread occurrence in the environment and biota, coupled with their known or suspected impacts on human health. Recent studies have shown that a significant portion of poly-PFASs remain unidentified. This study presents a time-of-flight mass spectrometry approach based on continuously interleaving scans at low and high collision energies (ToF-MS(E)) for the rapid identification and characterization of unknown PFASs. The MS(E) mode allowed for the simultaneous acquisition of full-spectrum accurate mass data of both parent and fragment ions in a single chromatographic run. Specific to PFASs, the hypothesis that PFASs can be selectively detected by the ToF-MS(E) high-resolution parent-ion search (HRPIS) of their characteristic fragments was confirmed with certified standards of 24 poly- and per-PFAS. After being validated with these certified standards, the innovative HRPIS approach was applied to a group of commercial surfactants, which led to the identification of 47 new and 43 infrequently reported PFASs, including 40 non-ionic, 30 cationic, 15 zwitterionic, and five anionic compounds. It is envisaged that the results, especially the identification of new non-ionic PFASs, may provide important insights into the historical occupational and non-occupational exposure to PFASs from the production and application of these surfactants. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Binding patterns of vanadium ions with different valence states to human serum transferrin studied by HPLC/high-resolution ICP-MS.

    PubMed

    Nagaoka, Megumi Hamano; Yamazaki, Takeshi; Maitani, Tamio

    2002-09-06

    Vanadium (V) is an essential metal for mammals and has different valence states. In blood, V is bound to serum transferrin (Tf), a glycoprotein which has two metal-binding sites, and carbonate is generally required for the binding. In this study, the binding patterns of V(III), V(IV), and V(V) to human serum Tf (hTf) were analyzed using an HPLC system equipped with an anion-exchange column and directly connected to a high-resolution inductively coupled plasma-mass spectrometer for metal detection (51V). In affinity to hTf, the three ions were ranked V(III)>V(IV)>V(V) in the presence of bicarbonate and V(III) reverse congruent V(IV)>V(V) in the absence. Intermediates in the "open forms" binding to the respective sites were detected at the initial stage. V(IV) and V(V) were bound to the N-lobe site in the "closed form" and "open form," respectively. In the absence of bicarbonate, V ions with respective valence states were bound to hTf in the "open form." In terms of binding to hTf, tri-valent V was most favorable in the presence of bicarbonate.

  1. Multiple-stage linear ion-trap with high resolution mass spectrometry towards complete structural characterization of phosphatidylethanolamines containing cyclopropane fatty acyl chain in Leishmania infantum.

    PubMed

    Hsu, Fong-Fu; Kuhlmann, F Matthew; Turk, John; Beverley, Stephen M

    2014-03-01

    The structures of phosphatidylethanolamine (PE) in Leishmania infantum are unique in that they consist of a rare cyclopropane fatty acid (CFA) containing PE subfamily, including CFA-containing plasmalogen PE species. In this contribution, we applied multiple-stage linear ion-trap combined with high-resolution mass spectrometry to define the structures of PEs that were desorbed as [M - H](-) and [M - H + 2Li](+) ions by ESI, respectively. The structural information arising from MS(n) on both the molecular species are complimentary, permitting complete determination of PE structures, including the identities of the fatty acid substituents and their location on the glycerol backbone, more importantly, the positions of the double bond(s) and of the cyclopropane chain of the fatty acid chain, directing to the realization of the CFA biosynthesis pathways that were reported previously. We also uncovered the presence of a minor dimethyl-PE subclass that has not been previously reported in L. infantum. This LIT MS(n) mass spectrometric approach led to unambiguous identification of PE molecules including many isomers in complex mixture that would otherwise be very difficult to define using other analytical approaches. Copyright © 2014 John Wiley & Sons, Ltd.

  2. [Determination of free carcinogenic aromatic amines in textiles by ultra-performance liquid chromatography-linear ion trap/orbitrap high resolution mass spectrometry].

    PubMed

    Ye, Xiwen; Peng, Yan; Niu, Zengyuan; Gao, Yonggang; Luo, Xin; Zou, Li

    2015-04-01

    A method of ultra-performance liquid chromatography-linear ion trap/orbitrap high resolution mass spectrometry (UPLC-LTQ/Orbitrap MS) was used to determine 24 free carcinogenic aromatic amines in textiles. The main factors influencing the method, including the extraction solvent, the extraction temperature and the extraction time, were optimized. Under the optimized experimental conditions, the analytes were extracted by dichloromethane for 10 min and loaded into a ZORBAX SB-C18 column (150 mm x 2.1 mm, 5 µm) with a gradient elution of methanol and 0.1% aqueous formic acid solution, and finally detected by LTQ/Orbitrap MS. The screening and quantitative analysis were carried out by the accurate mass of quasi-molecular ion and the peak in extracted chromatogram with accurate mass respectively. The correlation coefficients (R2) were higher than 0.99. The recoveries were 87.8%-105.6% with the RSDs were 1.6%-3.4%. The limits of detection were 0.5-1 µg/kg, and the limits of quantification were 1.5-3 µg/kg. The proposed method was applied to 14 textile samples containing spandex. 4,4'-Diaminodiphenylmethane was determined in five samples and the contents were 0.21-25.6 mg/kg. The results indicate that the developed method is a simple, efficient, precise and reliable technique for the determination of free carcinogenic aromatic amines in textiles.

  3. Heavy ion action on single cells: Cellular inactivation capability of single accelerated heavy ions

    NASA Technical Reports Server (NTRS)

    Kost, M.; Pross, H.-D.; Russmann, C.; Schneider, E.; Kiefer, J.; Kraft, G.; Lenz, G.; Becher, W.

    1994-01-01

    Heavy ions (HZE-particles) constitute an important part of radiation in space. Although their number is small the high amount of energy transferred by individual particles may cause severe biological effects. Their investigation requires special techniques which were tested by experiments performed at the UNILAC at the GSI (Darmstadt). Diploid yeast was used which is a suitable eucaryotic test system because of its resistance to extreme conditions like dryness and vacuum. Cells were placed on nuclear track detector foils and exposed to ions of different atomic number and energy. To assess the action of one single ion on an individual cell, track parameters and the respective colony forming abilities (CFA) were determined with the help of computer aided image analysis. There is mounting evidence that not only the amount of energy deposited along the particle path, commonly given by the LET, is of importance but also the spatial problem of energy deposition at a submicroscopical scale. It is virtually impossible to investigate track structure effects in detail with whole cell populations and (globally applied) high particle fluences. It is, therefore, necessary to detect the action of simple ions in individual cells. The results show that the biological action depends on atomic number and specific energy of the impinging ions, which can be compared with model calculations of recent track structure models.

  4. THERMALIZATION OF HEAVY IONS IN THE SOLAR WIND

    SciTech Connect

    Tracy, Patrick J.; Kasper, Justin C.; Zurbuchen, Thomas H.; Raines, Jim M.; Shearer, Paul; Gilbert, Jason

    2015-10-20

    Observations of velocity distribution functions from the Advanced Composition Explorer/Solar Wind Ion Composition Spectrometer heavy ion composition instrument are used to calculate ratios of kinetic temperature and Coulomb collisional interactions of an unprecedented 50 ion species in the solar wind. These ions cover a mass per charge range of 1–5.5 amu/e and were collected in the time range of 1998–2011. We report the first calculation of the Coulomb thermalization rate between each of the heavy ion (A > 4 amu) species present in the solar wind along with protons (H{sup +}) and alpha particles (He{sup 2+}). From these rates, we find that protons are the dominant source of Coulomb collisional thermalization for heavy ions in the solar wind and use this fact to calculate a collisional age for those heavy ion populations. The heavy ion thermal properties are well organized by this collisional age, but we find that the temperature of all heavy ions does not simply approach that of protons as Coulomb collisions become more important. We show that He{sup 2+} and C{sup 6+} follow a monotonic decay toward equal temperatures with protons with increasing collisional age, but O{sup 6+} shows a noted deviation from this monotonic decay. Furthermore, we show that the deviation from monotonic decay for O{sup 6+} occurs in solar wind of all origins, as determined by its Fe/O ratio. The observed differences in heavy ion temperature behavior point toward a local heating mechanism that favors ions depending on their charge and mass.

  5. Solar heavy ion Heinrich fluence spectrum at low earth orbit.

    PubMed

    Croley, D R; Spitale, G C

    1998-01-01

    Solar heavy ions from the JPL Solar Heavy Ion Model have been transported into low earth orbit using the Schulz cutoff criterion for L-shell access by ions of a specific charge to mass ratio. The NASA Brouwer orbit generator was used to get L values along the orbit at 60 second time intervals. Heavy ion fluences of ions 2 < or = Z < or = 92 have been determined for the LET range 1 to 130 MeV-cm2/mg by 60, 120 or 250 mils of aluminum over a period of 24 hours in a 425 km circular orbit inclined 51 degrees. The ion fluence is time dependent in the sense that the position of the spacecraft in the orbit at the flare onset time fixes the relationship between particle flux and spacecraft passage through high L-values where particles have access to the spacecraft.

  6. Comparing Tsallis and Boltzmann temperatures from relativistic heavy ion collider and large hadron collider heavy-ion data

    NASA Astrophysics Data System (ADS)

    Gao, Y.-Q.; Liu, F.-H.

    2016-03-01

    The transverse momentum spectra of charged particles produced in Au + Au collisions at the relativistic heavy ion collider and in Pb + Pb collisions at the large hadron collider with different centrality intervals are described by the multisource thermal model which is based on different statistic distributions for a singular source. Each source in the present work is described by the Tsallis distribution and the Boltzmann distribution, respectively. Then, the interacting system is described by the (two-component) Tsallis distribution and the (two-component) Boltzmann distribution, respectively. The results calculated by the two distributions are in agreement with the experimental data of the Solenoidal Tracker At Relativistic heavy ion collider, Pioneering High Energy Nuclear Interaction eXperiment, and A Large Ion Collider Experiment Collaborations. The effective temperature parameters extracted from the two distributions on the descriptions of heavy-ion data at the relativistic heavy ion collider and large hadron collider are obtained to show a linear correlation.

  7. Heavy Quarkonium Dissociation Cross Sections in Relativistic Heavy-Ion Collisions

    SciTech Connect

    C.-Y. Wong; Eric Swanson; Ted Barnes

    2001-12-01

    Many of the hadron-hadron cross sections required for the study of the dynamics of matter produced in relativistic heavy-ion collisions can be calculated using the quark-interchange model. Here we evaluate the low-energy dissociation cross sections of J/{psi}, {psi}', {chi}, {Upsilon}, and {Upsilon}' in collision with {pi}, {rho}, and K, which are important for the interpretation of heavy-quarkonium suppression as a signature for the quark gluon plasma. These comover dissociation processes also contribute to heavy-quarkonium suppression, and must be understood and incorporated in simulations of heavy-ion collisions before QGP formation can be established through this signature.

  8. Positrons from heavy ions: A puzzle for physicists

    SciTech Connect

    Mueller, B.

    1986-10-15

    A review of experimental data and models for positron production in relativistic heavy ion reactions is presented. The mass range of nuclei is A = 180--247 (nuclear charge range is Z1+Z2 = 163--188). (AIP)

  9. Silicon Carbide Power Device Performance Under Heavy-Ion Irradiation

    NASA Technical Reports Server (NTRS)

    Lauenstein, Jean-Marie; Casey, Megan; Topper, Alyson; Wilcox, Edward; Phan, Anthony; Ikpe, Stanley; LaBel, Ken

    2015-01-01

    Heavy-ion induced degradation and catastrophic failure data for SiC power MOSFETs and Schottky diodes are examined to provide insight into the challenge of single-event effect hardening of SiC power devices.

  10. Failure Analysis of Heavy-Ion-Irradiated Schottky Diodes

    NASA Technical Reports Server (NTRS)

    Casey, Megan C.; Lauenstein, Jean-Marie; Wilcox, Edward P.; Topper, Alyson D.; Campola, Michael J.; Label, Kenneth A.

    2017-01-01

    In this work, we use high- and low-magnitude optical microscope images, infrared camera images, and scanning electron microscope images to identify and describe the failure locations in heavy-ion-irradiated Schottky diodes.

  11. Elastic recoil detection analysis on the ANSTO heavy ion microprobe

    NASA Astrophysics Data System (ADS)

    Siegele, R.; Orlic, I.; Cohen, David D.

    2002-05-01

    The heavy ion microprobe at the Australian Nuclear Science and Technology Organisation is capable of focussing heavy ions with an ME/ q2 of up to 100 amu MeV. This makes the microprobe ideally suited for heavy ion elastic recoil detection analysis (ERDA). However, beam currents on a microprobe are usually very small, which requires a detection system with a large solid angle. We apply microbeam heavy ion ERDA using a large solid angle ΔE- E telescope with a gas ΔE detector to layered structures. We demonstrate the capability to measure oxygen and carbon with a lateral resolution of 20 μm, together with determination of the depth of the contamination in thin deposited layers.

  12. Theoretical perspective on RHIC (relativistic heavy ion collider) physics

    SciTech Connect

    Dover, C.B.

    1990-10-01

    We discuss the status of the relativistic heavy ion collider (RHIC) project at Brookhaven, and assess some key experiments which propose to detect the signatures of a transient quark-gluon plasma (QGP) phase in such collisions. 24 refs.

  13. Report of the heavy-ion fusion task group

    SciTech Connect

    Sawyer, G.A.; Booth, L.A.; Henderson, D.B.; Jameson, R.A.; Kindel, J.M.; Knapp, E.A.; Pollock, R.; Talbert, W.L.; Thode, L.E.; Williams, J.M.

    1980-02-01

    An assessment of heavy-ion fusion has been completed. Energetic heavy ions, for example 10-GeV uranium, provided by an rf linac or an induction linac, are used as alternatives to laser light to drive inertial confinement fusion pellets. The assessment has covered accelerator technology, transport of heavy-ion beams, target interaction physics, civilian power issues, and military applications. It is concluded that particle accelerators promise to be efficient pellet drivers, but that there are formidable technical problems to be solved. It is recommended that a moderate level research program on heavy-ion fusion be pursued and that LASL should continue to work on critical issues in accelerator development, beam transport, reactor systems studies, and target physics over the next few years.

  14. Mass defect filtering-oriented classification and precursor ions list-triggered high-resolution mass spectrometry analysis for the discovery of indole alkaloids from Uncaria sinensis.

    PubMed

    Pan, Huiqin; Yang, Wenzhi; Yao, Changliang; Shen, Yao; Zhang, Yibei; Shi, Xiaojian; Yao, Shuai; Wu, Wanying; Guo, Dean

    2017-09-22

    Discovery of new natural compounds is becoming increasingly challenging because of the interference from those known and abundant components. The aim of this study is to report a dereplication strategy, by integrating mass defect filtering (MDF)-oriented novelty classification and precursor ions list (PIL)-triggered high-resolution mass spectrometry analysis, and to validate it by discovering new indole alkaloids from the medicinal herb Uncaria sinensis. Rapid chromatographic separation was achieved on a Kinetex(®) EVO C18 column (<16min). An in-house MDF algorithm, developed based on the informed phytochemistry information and molecular design, could more exactly screen the target alkaloids and divide them into three novelty levels: Known (KN), Unknown-but-Predicted (UP), and Unexpected (UN). A hybrid data acquisition method, namely PIL-triggered collision-induced dissociation-MS(2) and high-energy C-trap dissociation-MS(3) with dynamic exclusion on a linear ion trap/Orbitrap mass spectrometer, facilitated the acquisition of diverse product ions sufficient for the structural elucidation of both indole alkaloids and the N-oxides. Ultimately, 158 potentially new alkaloids, including 10 UP and 108 UN, were rapidly characterized from the stem, leaf, and flower of U. sinensis. Two new alkaloid compounds thereof were successfully isolated and identified by 1D and 2D NMR analyses. The varied ring E and novel alkaloid-acylquinic acid conjugates were first reported from the whole Uncaria genus. Conclusively, it is a practical chemical dereplication strategy that can enhance the efficiency and has the potential to be a routine approach for the discovery of new natural compounds. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Heavy Ion Current Transients in SiGe HBTs

    NASA Technical Reports Server (NTRS)

    Pellish, Jonathan A.; Reed, Robert A.; Vizkelethy, Gyorgy; McMorrow, Dale; Ferlet-Cavrois, Veronique; Baggio, Jacques; Paillet, Philipe; Duhanel, Olivier; Phillips, Stanley D.; Sutton, Akil K.; hide

    2009-01-01

    Time-resolved ion beam induced charge reveals heavy ion response of IBM 5AM SiGe HBT: a) Position correlation[ b) Unique response for different bias schemes; c) Similarities to TPA pulsed-laser data. Heavy ion broad-beam transients provide more realistic device response: a) Feedback using microbeam data; b) Overcome issues of LET and ion range with microbeam. Both micro- and broad-beam data sets yield valuable input for TCAD simulations. Uncover detailed mechanisms for SiGe HBTs and other devices fabricated on lightly-doped substrates.

  16. High-resolution continuum source graphite furnace molecular absorption spectrometry compared with ion chromatography for quantitative determination of dissolved fluoride in river water samples.

    PubMed

    Ley, Philip; Sturm, Manfred; Ternes, Thomas A; Meermann, Björn

    2017-10-03

    In addition to beneficial health effects, fluoride can also have adverse effects on humans, animals, and plants if the daily intake is strongly elevated. One main source of fluoride uptake is water, and thus several ordinances exist in Germany that declare permissible concentrations of fluoride in, for example, drinking water, mineral water, and landfill seepage water. Controlling the fluoride concentrations in aqueous matrices necessitate valid and fast analytical methods. In this work an alternative method for the determination of fluoride in surface waters based on high-resolution continuum source graphite furnace molecular absorption spectrometry (HR-CS-GFMAS) was applied. Fluoride detection was made possible by the formation of a diatomic molecule, GaF, and detection of characteristic molecular absorption. On HR-CS-GFMAS parameter optimization, the method was adapted to surface water sample analysis. The influence of potential main matrix constituents such as Na(+), Ca(2+), Mg(2+), and Cl(-) as well as surface water sampling/storage conditions on the molecular absorption signal of GaF was investigated. Method validation demonstrated a low limit of detection (8.1 μg L(-1)) and a low limit of quantification (26.9 μg L(-1)), both sufficient for direct river water sample analysis after 0.45-μm filtration. The optimized HR-CS-GFMAS method was applied for the analysis of real water samples from the rivers Rhine and Moselle. For method validation, samples were also analyzed by an ion chromatography (IC) method. IC and HR-CS-GFMAS results both agreed well. In comparison with IC, HR-CS-GFMAS has higher sample throughput, a lower limit of detection and a lower limit of quantification, and higher selectivity, and is a very suitable method for the analysis of dissolved fluoride in river water. Graphical abstract High-resolution continuum source graphite furnace molecular absorption spectrometry (HR-CS-GFMAS) was applied for the quantitative analysis of dissolved

  17. Antiproton production in heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Jacak, B. V.

    In high energy p-p and alpha-alpha collisions, baryons are observed predominantly at rapidities near those of target and projectile; the mean rapidity shift of projectile and target nucleons is approximately one unit. In the central rapidity region, the number of baryons is quite small. In fact, the number of baryons and antibaryons is rather similar, indicating that most of these baryons are CREATED particles rather than projectile and target fragments. Antibaryon production is of interest in heavy ion collisions as enhanced antiquark production has been predicted as a potential signature of quark-gluon plasma formation. Antibaryons also provide a sensitive probe of the hadronic environment, via annihilation and/or mean field effects upon their final distributions. However, the collision dynamics also affect the baryon and antibaryon distributions. Baryons are more shifted toward midrapidity in nucleus-nucleus and p-p nucleus collisions than in p-p collisions, increasing the probability of annihilating the antibaryons. The interpretation of antibaryon yields is further complicated by collective processes which may take place in the dense hadronic medium formed in nucleus-nucleus collisions. Jahns and coworkers have shown that multistep processes can increase antibaryon production near threshold. Antiproton production is clearly very interesting, but is sensitive to a combination of processes taking place in the collision. The final number of observed antiprotons depends on the balance between mechanisms for extra antiproton production beyond those from the individual nucleon-nucleon collisions and annihilation with surrounding baryons. We can hope to sort out these things by systematic studies, varying the system size and beam energy. I will review what is known about antiproton production at both the AGS and SPS, and look at trends going from p-p to p-nucleus to nucleus-nucleus collisions.

  18. The Relativistic Heavy Ion Collider control system

    SciTech Connect

    Clifford, T.S.; Barton, D.S.; Oerter, B.R.

    1997-12-01

    The Relativistic Heavy Ion Collider control system has been used in the commissioning of the AGS to RHIC transfer line and in the first RHIC sextant test. Much of the controls infrastructure for networks and links has been installed throughout the collider. All of the controls hardware modules needed to be built for early RHIC operations have been designed and tested. Many of these VME modules are already being used in normal AGS operations. Over 150 VME based front end computers and device controllers will be installed by the Summer of 1998 in order to be ready for Fall of 1998. A few features are being added to the front end computer core software. The bulk of the Accelerator Device Objects (ADOs) which are instantiated in the FECs, have been written and tested in the early commissioning. A configuration database has been designed. Generic control and display of ADO parameters via a spreadsheet like program on the console level computers was provided early on in the control system development. User interface tools that were developed for the AGS control system have been used in RHIC applications. Some of the basic operations programs, like alarm display and save/restore, that are used in the AGS operations have been or will be expanded to support RHIC operations. A model for application programs which involves a console level manager servicing ADOs have been verified with a few RHIC applications. More applications need to be written for the Fall of 1998 commissioning effort. A sequencer for automatic control of the fill is being written with the expectation that it will be useful in early commissioning.

  19. An optical dosimeter for monitoring heavy metal ions in water

    NASA Astrophysics Data System (ADS)

    Mignani, Anna G.; Regan, Fiona; Leamy, D.; Mencaglia, A. A.; Ciaccheri, L.

    2005-05-01

    This work presents an optochemical dosimeter for determining and discriminating nickel, copper, and cobalt ions in water that can be used as an early warning system for water pollution. An inexpensive fiber optic spectrophotometer monitors the sensor's spectral behavior under exposure to water solutions of heavy metal ions in the 1-10 mg/l concentration range. The Principal Component Analysis (PCA) method quantitatively determines the heavy metals and discriminates their type and combination.

  20. Engineering systems designs for a recirculating heavy ion induction accelerator

    SciTech Connect

    Newton, M.A.; Barnard, J.J.; Reginato, L.L.; Yu, S.S.

    1991-05-01

    Recirculating heavy ion induction accelerators are being investigated as possible drivers for heavy ion fusion. Part of this investigation has included the generation of a conceptual design for a recirculator system. This paper will describe the overall engineering conceptual design of this recirculator, including discussions of the dipole magnet system, the superconducting quadrupole system and the beam acceleration system. Major engineering issues, evaluation of feasibility, and cost tradeoffs of the complete recirculator system will be presented and discussed. 5 refs., 4 figs.

  1. High baryon density from relativistic heavy ion collisions

    SciTech Connect

    Pang, Y.; Kahana, S.H.; Schlagel, T.J. |

    1993-10-01

    A quantitative model, based on hadronic physics, is developed and applied to heavy ion collisions at BNL-AGS energies. This model is in excellent agreement with observed particle spectra in heavy ion collisions using Si beams, where baryon densities of three and four times the normal nuclear matter density ({rho}{sub 0}) are reached. For Au on Au collisions, the authors predict the formation of matter at very high densities (up to 10 {rho}{sub 0}).

  2. Pion correlations in relativistic heavy ion collisions at Heavy Ion Spectrometer Systems (HISS)

    SciTech Connect

    Christie, W.B. Jr.

    1990-05-01

    This thesis contains the setup, analysis and results of experiment E684H Multi-Pion Correlations in Relativistic Heavy Ion Collisions''. The goals of the original proposal were: (1) To initiate the use of the HISS facility in the study of central Relativistic Heavy Ion Collisions (RHIC). (2) To perform a second generation experiment for the detailed study of the pion source in RHIC. The first generation experiments, implied by the second goal above, refer to pion correlation studies which the Riverside group had performed at the LBL streamer chamber. The major advantage offered by moving the pion correlation studies to HISS is that, being an electronic detector system, as opposed to the Streamer Chamber which is a visual detector, one can greatly increase the statistics for a study of this sort. An additional advantage is that once one has written the necessary detector and physics analysis code to do a particular type of study, the study may be extended to investigate the systematics, with much less effort and in a relatively short time. This paper discusses the Physics motivation for this experiment, the experimental setup and detectors used, the pion correlation analysis, the results, and the conclusions possible future directions for pion studies at HISS. If one is not interested in all the details of the experiment, I believe that by reading the sections on intensity interferometry, the section the fitting of the correlation function and the systematic corrections applied, and the results section, one will get a fairly complete synopsis of the experiment.

  3. Ion exchange extraction of heavy metals from wastewater sludges.

    PubMed

    Al-Enezi, G; Hamoda, M F; Fawzi, N

    2004-01-01

    Heavy metals are common contaminants of some industrial wastewater. They find their way to municipal wastewaters due to industrial discharges into the sewerage system or through household chemicals. The most common heavy metals found in wastewaters are lead, copper, nickel, cadmium, zinc, mercury, arsenic, and chromium. Such metals are toxic and pose serious threats to the environment and public health. In recent years, the ion exchange process has been increasingly used for the removal of heavy metals or the recovery of precious metals. It is a versatile separation process with the potential for broad applications in the water and wastewater treatment field. This article summarizes the results obtained from a laboratory study on the removal of heavy metals from municipal wastewater sludges obtained from Ardhiya plant in Kuwait. Data on heavy metal content of the wastewater and sludge samples collected from the plant are presented. The results obtained from laboratory experiments using a commercially available ion exchange resin to remove heavy metals from sludge were discussed. A technique was developed to solubilize such heavy metals from the sludge for subsequent treatment by the ion exchange process. The results showed high efficiency of extraction, almost 99.9%, of heavy metals in the concentration range bound in wastewater effluents and sludges. Selective removal of heavy metals from a contaminated wastewater/sludge combines the benefits of being economically prudent and providing the possibility of reuse/recycle of the treated wastewater effluents and sludges.

  4. Characterization of highly efficient heavy-ion mutagenesis in Arabidopsis thaliana

    PubMed Central

    2011-01-01

    Background Heavy-ion mutagenesis is recognised as a powerful technology to generate new mutants, especially in higher plants. Heavy-ion beams show high linear energy transfer (LET) and thus more effectively induce DNA double-strand breaks than other mutagenic techniques. Previously, we determined the most effective heavy-ion LET (LETmax: 30.0 keV μm-1) for Arabidopsis mutagenesis by analysing the effect of LET on mutation induction. However, the molecular structure of mutated DNA induced by heavy ions with LETmax remains unclear. Knowledge of the structure of mutated DNA will contribute to the effective exploitation of heavy-ion beam mutagenesis. Results Dry Arabidopsis thaliana seeds were irradiated with carbon (C) ions with LETmax at a dose of 400 Gy and with LET of 22.5 keV μm-1 at doses of 250 Gy or 450 Gy. The effects on mutation frequency and alteration of DNA structure were compared. To characterise the structure of mutated DNA, we screened the well-characterised mutants elongated hypocotyls (hy) and glabrous (gl) and identified mutated DNA among the resulting mutants by high-resolution melting curve, PCR and sequencing analyses. The mutation frequency induced by C ions with LETmax was two-fold higher than that with 22.5 keV μm-1 and similar to the mutation frequency previously induced by ethyl methane sulfonate. We identified the structure of 22 mutated DNAs. Over 80% of the mutations caused by C ions with both LETs were base substitutions or deletions/insertions of less than 100 bp. The other mutations involved large rearrangements. Conclusions The C ions with LETmax showed high mutation efficiency and predominantly induced base substitutions or small deletions/insertions, most of which were null mutations. These small alterations can be determined by single-nucleotide polymorphism (SNP) detection systems. Therefore, C ions with LETmax might be useful as a highly efficient reverse genetic system in conjunction with SNP detection systems, and will be

  5. High Resolution Computed Tomography

    DTIC Science & Technology

    1992-07-31

    samples. 14. SUBJECTTERMS 15. NUMBER OF PAGES 38 High Resolution, Microfocus , Characterization, X - Ray , Micrography, Computed Tomography (CT), Failure...high resolutions (50 g.tm feature sensitivity) when a small field of view (50 mm) is used [11]. Specially designed detectors and a microfocus X - ray ...Wright Laboratories. Feldkamp [14] at Ford used a microfocus X - ray source and an X - ray image intensifier to develop a system capable of 20 g.m

  6. Rapid characterization of lithium ion battery electrolytes and thermal aging products by low-temperature plasma ambient ionization high-resolution mass spectrometry.

    PubMed

    Vortmann, Britta; Nowak, Sascha; Engelhard, Carsten

    2013-03-19

    Lithium ion batteries (LIBs) are key components for portable electronic devices that are used around the world. However, thermal decomposition products in the battery reduce its lifetime, and decomposition processes are still not understood. In this study, a rapid method for in situ analysis and reaction monitoring in LIB electrolytes is presented based on high-resolution mass spectrometry (HR-MS) with low-temperature plasma probe (LTP) ambient desorption/ionization for the first time. This proof-of-principle study demonstrates the capabilities of ambient mass spectrometry in battery research. LTP-HR-MS is ideally suited for qualitative analysis in the ambient environment because it allows direct sample analysis independent of the sample size, geometry, and structure. Further, it is environmental friendly because it eliminates the need of organic solvents that are typically used in separation techniques coupled to mass spectrometry. Accurate mass measurements were used to identify the time-/condition-dependent formation of electrolyte decomposition compounds. A LIB model electrolyte containing ethylene carbonate and dimethyl carbonate was analyzed before and after controlled thermal stress and over the course of several weeks. Major decomposition products identified include difluorophosphoric acid, monofluorophosphoric acid methyl ester, monofluorophosphoric acid dimethyl ester, and hexafluorophosphate. Solvents (i.e., dimethyl carbonate) were partly consumed via an esterification pathway. LTP-HR-MS is considered to be an attractive method for fundamental LIB studies.

  7. Surface structures of binary mixtures of imidazolium-based ionic liquids using high-resolution Rutherford backscattering spectroscopy and time of flight secondary ion mass spectroscopy

    NASA Astrophysics Data System (ADS)

    Nakajima, Kaoru; Miyashita, Motoki; Suzuki, Motofumi; Kimura, Kenji

    2013-12-01

    Surface structures of binary mixtures of imidazolium-based ionic liquids having a common anion (bis(trifluoromethanesulfonyl)imide ([TFSI]), namely [C2MIM]1-x[C10MIM]x[TFSI] (x = 0.5 and 0.1), are studied using high-resolution Rutherford backscattering spectroscopy (HRBS) and time of flight secondary ion mass spectroscopy (TOF-SIMS). Although both measurements show surface segregation of [C10MIM] the degrees of the segregation are different. The surface fraction xsurf of [C10MIM] is estimated to be 0.6 ± 0.05 and 0.18 ± 0.02 by HRBS for x = 0.5 and 0.1, respectively. On the other hand, TOF-SIMS indicates much stronger surface segregation, namely xsurf = 0.83 ± 0.03 and 0.42 ± 0.04 for x = 0.5 and 0.1, respectively. The observed discrepancy can be attributed to the difference in the probing depth between HRBS and TOF-SIMS. The observed surface segregation can be roughly explained in terms of surface tension.

  8. Surface structures of binary mixtures of imidazolium-based ionic liquids using high-resolution Rutherford backscattering spectroscopy and time of flight secondary ion mass spectroscopy.

    PubMed

    Nakajima, Kaoru; Miyashita, Motoki; Suzuki, Motofumi; Kimura, Kenji

    2013-12-14

    Surface structures of binary mixtures of imidazolium-based ionic liquids having a common anion (bis(trifluoromethanesulfonyl)imide ([TFSI]), namely [C2MIM]1-x[C10MIM]x[TFSI] (x = 0.5 and 0.1), are studied using high-resolution Rutherford backscattering spectroscopy (HRBS) and time of flight secondary ion mass spectroscopy (TOF-SIMS). Although both measurements show surface segregation of [C10MIM] the degrees of the segregation are different. The surface fraction xsurf of [C10MIM] is estimated to be 0.6 ± 0.05 and 0.18 ± 0.02 by HRBS for x = 0.5 and 0.1, respectively. On the other hand, TOF-SIMS indicates much stronger surface segregation, namely xsurf = 0.83 ± 0.03 and 0.42 ± 0.04 for x = 0.5 and 0.1, respectively. The observed discrepancy can be attributed to the difference in the probing depth between HRBS and TOF-SIMS. The observed surface segregation can be roughly explained in terms of surface tension.

  9. High-resolution secondary ion mass spectrometry analysis of carbon dynamics in mycorrhizas formed by an obligately myco-heterotrophic orchid.

    PubMed

    Bougoure, Jeremy; Ludwig, Martha; Brundrett, Mark; Cliff, John; Clode, Peta; Kilburn, Matt; Grierson, Pauline

    2014-05-01

    Mycorrhiza formation represents a significant carbon (C) acquisition alternative for orchid species, particularly those that remain achlorophyllous through all life stages. As it is known that orchid mycorrhizas facilitate nutrient transfer (most notably of C), it has not been resolved if C transfer occurs only after lysis of mycorrhizal structures (fungal pelotons) or also across the mycorrhizal interface of pre-lysed pelotons. We used high-resolution secondary ion mass spectrometry (nanoSIMS) and labelling with enriched (13) CO2 to trace C transfers, at subcellular scale, across mycorrhizal interfaces formed by Rhizanthella gardneri, an achlorphyllous orchid. Carbon was successfully traced in to the fungal portion of orchid mycorrhizas. However, we did not detect C movement across intact mycorrhizal interfaces up to 216 h post (13) CO2 labelling. Our findings provide support for the hypothesis that C transfer from the mycorrhizal fungus to orchid, at least for R. gardneri, likely occurs after lysis of the fungal peloton.

  10. High-resolution Fourier transform emission spectroscopy of the A˜ 2Πi -X˜ 2Πi band of the OCS+ ion

    NASA Astrophysics Data System (ADS)

    Nakashima, Yoshihiro; Harada, Kensuke; Tanaka, Keiichi; Tanaka, Takehiko

    2017-04-01

    High resolution Fourier transform emission spectroscopy of the A˜ 2Πi -X˜ 2Πi band of the OCS+ ion was performed in the UV region to observe the ν1 (CO stretch) progression bands (υ1 = 0 → 2-5) for both the Ω =3 /2 and 1/2 spin components. Accurate molecular constants including the rotational constants, B0 = 0.194 765(13) and 0.187 106(13) cm-1, and the spin-orbit interaction constants, A0 = -381.0(56) and -126.5(56) cm-1, were determined for the X˜ 2Π and A˜ 2Π states, respectively, by the simultaneous analysis of the observed progression bands. The CO bond length (rCO = 1.2810 Å) for the A˜ 2Π state, derived from the rotational constant B0 and Franck-Condon factors, is longer by 0.1756 Å than that (1.1054 Å) for the X˜ 2Π state, while the CS bond length for the A˜ 2Π state is shorter by 0.0905 Å than that for the X˜ 2Π state. Pure rotational transition frequencies in the ground X˜ 2Π state are predicted, as well as transition frequencies of the ν1 fundamental band, with the present molecular constants.

  11. High-Resolution Secondary Ion Mass Spectrometry Reveals the Contrasting Subcellular Distribution of Arsenic and Silicon in Rice Roots1[C][W][OA

    PubMed Central

    Moore, Katie L.; Schröder, Markus; Wu, Zhongchang; Martin, Barry G.H.; Hawes, Chris R.; McGrath, Steve P.; Hawkesford, Malcolm J.; Feng Ma, Jian; Zhao, Fang-Jie; Grovenor, Chris R.M.

    2011-01-01

    Rice (Oryza sativa) takes up arsenite mainly through the silicic acid transport pathway. Understanding the uptake and sequestration of arsenic (As) into the rice plant is important for developing strategies to reduce As concentration in rice grain. In this study, the cellular and subcellular distributions of As and silicon (Si) in rice roots were investigated using high-pressure freezing, high-resolution secondary ion mass spectrometry, and transmission electron microscopy. Rice plants, both the lsi2 mutant lacking the Si/arsenite efflux transporter Lsi2 and its wild-type cultivar, with or without an iron plaque, were treated with arsenate or arsenite. The formation of iron plaque on the root surface resulted in strong accumulation of As and phosphorous on the epidermis. The lsi2 mutant showed stronger As accumulation in the endodermal vacuoles, where the Lsi2 transporter is located in the plasma membranes, than the wild-type line. As also accumulated in the vacuoles of some xylem parenchyma cells and in some pericycle cells, particularly in the wild-type mature root zone. Vacuolar accumulation of As is associated with sulfur, suggesting that As may be stored as arsenite-phytochelatin complexes. Si was localized in the cell walls of the endodermal cells with little apparent effect of the Lsi2 mutation on its distribution. This study reveals the vacuolar sequestration of As in rice roots and contrasting patterns of As and Si subcellular localization, despite both being transported across the plasma membranes by the same transporters. PMID:21490163

  12. Measurements of Oxidized Organic Compounds during SOAS 2013 using nitrate ion chemical ionization coupled with High Resolution Time-of-Flight Mass Spectrometry

    NASA Astrophysics Data System (ADS)

    Massoli, P.; Stark, H.; Cnagaratna, M.; Junninen, H.; Hakala, J. P.; Mauldin, R.; Ehn, M.; Sipila, M.; Krechmer, J.; Kimmel, J.; Jimenez, J. L.; Jayne, J. T.; Worsnop, D. R.

    2013-12-01

    We present ambient measurements of gaseous organic compounds by means of a High Resolution Time-of-Flight Chemical Ionization Mass Spectrometry (HR-ToF-CIMS) using nitrate ion (NO3-) chemistry. This technique allows to selectively detect oxidized gas-phase species, e.g., oxidized organic molecules and sulfuric acid via clustering with NO3- and its high order clusters. The capability of making such measurements is important because both sulfuric acid and organic gas molecules have a recognized key role in new particle formation (NPF) processes and likely have an important role in particulate phase chemistry and formation of secondary organic aerosols (SOA). The HR-ToF-CIMS was deployed during the Southern Oxidant and Aerosol Study (SOAS) at the forest supersite in Centreville, AL, from June 1 to July 15, 2013. The main goal of the SOAS campaign was to investigate the composition and sources of SOA in the Southeast US, where emissions are mainly represented by biogenic volatile organic compounds (BVOC) emissions and in less extent by anthropogenic emissions (AVOC). During SOAS, the HR-ToF-CIMS detected a range of organic ions that based on previous literature could be identified as oxidation products of both isoprene and terpenes. The isoprene products were 5 to 10 times more abundant than the terpene products. The isoprene-related molecules showed a diurnal cycle with a day time peak, typically after 1500 local time, while the terpene products were higher at night (between 2000 and 0600 local time). These results are consistent with the diurnal trends of primary BVOC emissions from other co-located instruments. The ambient data are also compared to laboratory measurements where oxidized organic vapors are produced using a Potential Aerosol Mass (PAM) flow reactor by the OH oxidation of biogenic gas-phase precursors (isoprene, a-pinene) over multiple days of equivalent atmospheric exposure.

  13. [Screening and confirmation of carcinogenic dyes in textiles by high performance liquid chromatography-linear ion trap/orbitrap high resolution mass spectrometry].

    PubMed

    Xiu, Xiaoli; Luo, Xin; Niu, Zengyuan; Ye, Xiwen; Zhixu, Tang; Li, Jingying; Wang, Yongwei; Du, Wei

    2013-10-01

    A method of high performance liquid chromatography-linear ion trap/Orbitrap high resolution mass spectrometry (HPLC-LTQ/Orbitrap MS) was used to screen and confirm carcinogenic dyes in textiles. The analytes were extracted from textile samples with pyridine/water (1/1, v/v) in a water bath under controlled conditions (95 degrees C, 150 r/min), and then filtered with a 0.22 microm polytetrafluoroetylene (PTFE) membrane. The eluates were separated on a CAPCELL PAK C18 column (100 mm x 2.0 mm, 5 microm) using gradient elution with acetonitrile/ 5 mmol/L ammonium acetate aqueous solution containing 0.01% formic acid (in positive mode) and acetonitrile/5 mmol/L ammonium acetate aqueous solution (in negative mode), and finally detected by HPLC-LTQ/Orbitrap MS in ESI modes. Full scan experiments were performed over the range of m/z 200-800. The screening and quantitative analysis were carried out by the accurate mass of quasi-molecular ion and the peak area in extracted chromatogram with accurate mass, respectively. The confirmatory analysis for target compounds was performed with the retention time and qualitative fragments obtained by data-dependent scan mode. Under the optimal conditions, nine carcinogenic dyes were routinely detected with mass accuracy below 5 x 10(-6) (5 ppm), and good linearities were provided in their respective linear ranges with correlation coefficients higher than 0.99. The limits of detection were in the range of 0.125-25 mg/kg. The average recoveries at three spiked levels were in the range of 62.13%116.28% with the relative standard deviations (RSDs) lower than 15%. The proposed method was applied to screen and confirm the nine carcinogenic dyes in textile samples. It is convenient and reliable.

  14. High-resolution determination of H+ by ion chromatography. Application to the simultaneous determination of H+, Na+, NH4+ and K+ in acid rain.

    PubMed

    Hu, W; Hasebe, K; Iles, A; Tanaka, K

    2001-06-01

    An ion chromatographic (IC) method was developed for the high-resolution determination of a sample's free hydrogen ion concentration (H+). Highly purified lithium dodecyl sulfate was used as the stationary phase, a slightly acidified aqueous LiCl solution was used as the mobile phase and conductivity was used for analyte detection. An electrical double layer (EDL) containing H+ was established on the stationary phase by using a slightly acidified electrolyte solution as the eluent. H+ in the EDL protonated any weak acid groups (i.e., silanols) on the stationary phase so that H+ from the sample could be retained/separated purely by dodecyl sulfate. The optimum molar ratio of H+:Li+ in the EDL for this IC system was obtained by using an aqueous solution containing 40.0 mM LiCl and 0.07 mM H2SO4 as the eluent. After separation, H+ was detected by direct conductimetric measurement. An H+ detection limit of better than 8.2 x 10(-6) M was obtained from the analysis of standard aqueous H2SO4 solutions. Other monovalent cations could also be separated with this method, giving detection limits of 7.4 x 10(-5), 4.3 x 10(-5) and 4.2 x 10(-5) M for Na+, NH4+ and K+, respectively. The method was applied to the simultaneous determination of H+, Na+, NH4+ and K+ in acid rain. The results obtained showed a significant improvement in reproducibility when compared with those from a conventional pH-meter. Acid rain samples with a pH < 5 could be analyzed with this IC system.

  15. Removal of heavy metal ions from wastewaters: a review.

    PubMed

    Fu, Fenglian; Wang, Qi

    2011-03-01

    Heavy metal pollution has become one of the most serious environmental problems today. The treatment of heavy metals is of special concern due to their recalcitrance and persistence in the environment. In recent years, various methods for heavy metal removal from wastewater have been extensively studied. This paper reviews the current methods that have been used to treat heavy metal wastewater and evaluates these techniques. These technologies include chemical precipitation, ion-exchange, adsorption, membrane filtration, coagulation-flocculation, flotation and electrochemical methods. About 185 published studies (1988-2010) are reviewed in this paper. It is evident from the literature survey articles that ion-exchange, adsorption and membrane filtration are the most frequently studied for the treatment of heavy metal wastewater.

  16. Jets in heavy ion collisions at the LHC

    NASA Astrophysics Data System (ADS)

    Roland, Christof

    2015-11-01

    In this document I present a brief review of the concepts of jet physics employed in heavy ion physics. Fast partons originating from scatterings with large momentum transfer are produced at very short time-scales and subsequently propagate through the strongly interacting medium produced in the collisions of heavy nuclei. They feature the only experimental handle available to directly study the interaction of a well defined probe and the medium. Consequently they are ideally suited to investigate the nature of the medium produced in these collisions and the mechanism of interaction between the medium and the partons. The experimental methods necessary to reconstruct jets originating from fragmenting partons in the environment of high particle multiplicity heavy ion collisions will be discussed. Physics observables suited to investigate the parton medium interaction will be introduced and a summary of recent results on jet physics in heavy ion collisions is presented.

  17. High resolution ion microprobe investigation of the δ18O of carbonate cements (Jurassic, Paris Basin, France): New insights and pending questions

    NASA Astrophysics Data System (ADS)

    Vincent, Benoit; Brigaud, Benjamin; Emmanuel, Laurent; Loreau, Jean-Paul

    2017-04-01

    The scope of this work is to investigate, at a high resolution, the oxygen isotope composition (δ18Ocarb) of diagenetic products (synsedimentary and burial calcite cements) in shallow-marine carbonates. SIMS (Secondary Ion Mass Spectrometry) microprobe analyses were performed on thin sections from Oxfordian and Kimmeridgian Formations of the eastern Paris Basin and compared to data obtained on the same diagenetic products by conventional mass spectrometry (acid digestion). Hereby obtained, δ18O are similar, but the SIMS dataset displays a larger range of values. The isotopic zonation obtained by SIMS transects through sequences of cements filling pores, reveals an (expected) isotopic depletion from older stage synsedimentary calcites to younger stage blocky calcites and that follows the CL (cathodoluminescence) zonation. SIMS analyses however show that synsedimentary cements precipitated in intra-skeletal pores, have heavier δ18O than their inter-particle counterparts, with an offset of + 4‰V-PDB, despite similar petrographical characteristics. This difference is maintained in the δ18O of the first stages of blocky calcite cements, intra-skeletal blocky calcites showing heavier δ18O than the time equivalent and petrographically identical inter-particle calcites, with an offset of + 5‰V-PDB. These offsets are tentatively explained by the precipitation of cements under non-equilibrium conditions in intra-skeletal pores, where organic matter decay may have played a key role, acting notably on the pH. The occurrence of isolated micro-diagenetic environments, co-existing at the thin section scale, is tentatively proposed as an explanation to these small scale and high amplitude δ18O heterogeneities. These results may question the sampling strategy for future works. Microdrilling may miss the observed range of variation, but averaging the values may not necessarily lead to real misinterpretations if a critical selection of samples is performed, targeting

  18. ON A NEW TYPE OF ACCELERATOR FOR HEAVY IONS.

    DTIC Science & Technology

    A new device (called HIPAC - Heavy Ion Plasma Accelerator) which may be capable of accelerating ions of any atomic number to energies sufficient to...achieved in this way would allow a wide variety of nuclear reactions to be studied, including inverse fission. The present primitive state of development of the HIPAC is described, and the future prospects assessed. (Author)

  19. LBL Wideroe-based heavy ion injector project

    SciTech Connect

    Staples, J.W.; Lancaster, H.D.; Yourd, R.B.

    1981-03-01

    The LBL Wideroe-based high-intensity heavy-ion injector for the SuperHILAC will be operational by April 1981. It will provide several emA of low charge state ions up through uranium at high duty factor to the SuperHILAC. Several of the subsystems have already operated to specification and will be described.

  20. Dynamical Aspects of Heavy-Ion Collisions

    NASA Astrophysics Data System (ADS)

    Garcia-Solis, Edmundo Javier

    1995-01-01

    Two independent studies on heavy-ion collisions are presented. In the first part, the charge and mass of the projectile-like fragments produced in the 15-MeV per nucleon ^{40}Ca+^{209 } Bi reaction were determined for products detected near the grazing angle. Neutron number-charge (N-Z) distributions were generated as a function of the total kinetic energy loss and parameterized by their centroids, variances and correlation coefficients. After the interaction, a drift of the charge and mass centroids towards asymmetry is observed. The production of projectile -like fragments is consistent with a tendency of the projectile -like fragments to retain the projectile neutron-to-proton ratio < N > / < Z > = 1. The correlation coefficient remains well below 1.0 for the entire range of total kinetic energy lost. Predictions of two nucleon exchange models, Randrup's and Tassan-Got's, are compared to the experimental results. The models are not able to reproduce the evolution of the experimental distributions, especially the fact that the variances reach a maximum and then decrease as function of the energy loss. This behavior supports the hypothesis that some form of projectile -like fragmentation or cluster emission is perturbing the product distribution from that expected from a damped mechanism. In the second part of the thesis a clustering model that allows the recognition of mass fragments from dynamical simulations has been developed. Studying the evolution of a microscopic computation based on the nuclear -Boltzman transport equation, a suitable time is chosen to identify the bound clusters. At this time the number of binding surfaces for each test nucleon is found. Based on the number of nucleon bindings the interior nucleons are identified, and the cluster kernels are formed. An iterative routine is then applied to determine the coalescence of the surrounding free nucleons. Once the fragment formation has been established, a statistical decay code is used to

  1. Neoplastic transformation of hamster embyro cells by heavy ions.

    PubMed

    Han, Z; Suzuki, H; Suzuki, F; Suzuki, M; Furusawa, Y; Kato, T; Ikenaga, M

    1998-01-01

    We have studied the induction of morphological transformation of Syrian hamster embryo cells by low doses of heavy ions with different linear energy transfer (LET), ranging from 13 to 400 keV/micrometer. Exponentially growing cells were irradiated with 12C or 28Si ion beams generated by the Heavy Ion Medical Accelerator in Chiba (HIMAC), inoculated to culture dishes, and transformed colonies were identified when the cells were densely stacked and showed a crisscross pattern. Over the LET range examined, the frequency of transformation induced by the heavy ions increased sharply at very low doses no greater than 5 cGy. The relative biological effectiveness (RBE) of the heavy ions relative to 250 kVp X-rays showed an initial increase with LET, reaching a maximum value of about 7 at 100 keV/micrometer, and then decreased with the further increase in LET. Thus, we confirmed that high LET heavy ions are significantly more effective than X-rays for the induction of in vitro cell transformation.

  2. Heavy ion beam transport and interaction with ICF targets

    NASA Astrophysics Data System (ADS)

    Velarde, G.; Aragonés, J. M.; Gago, J. A.; Gámez, L.; González, M. C.; Honrubia, J. J.; Martínez-Val, J. M.; Mínguez, E.; Ocaña, J. L.; Otero, R.; Perlado, J. M.; Santolaya, J. M.; Serrano, J. F.; Velarde, P. M.

    1986-01-01

    Numerical simulation codes provide an essential tool for analyzing the very broad range of concepts and variables considered in ICF targets. In this paper, the relevant processes embodied in the NORCLA code, needed to simulate ICF targets driven by heavy ion beams will be presented. Atomic physic models developed at DENIM to improve the atomic data needed for ion beam plasma interaction will be explained. Concerning the stopping power, the average ionization potential following a Thomas-Fermi model has been calculated, and results are compared with full quantum calculations. Finally, a parametric study of multilayered single shell targets driven by heavy ion beams will be shown.

  3. Energetic heavy ion dominance in the outer magnetosphere

    NASA Astrophysics Data System (ADS)

    Cohen, Ian; Mitchell, Don; Mauk, Barry; Anderson, Brian; Ohtani, Shin; Kistler, Lynn; Hamilton, Doug; Turner, Drew; Blake, Bern; Fennell, Joe; Jaynes, Allison; Leonard, Trevor; Gerrard, Andy; Lanzerotti, Lou; Burch, Jim

    2017-04-01

    Despite the extensive study of ring current ion composition, little exists in the literature regarding the nature of energetic ions with energies >200 keV, especially in the outer magnetosphere (r > 9 RE). In particular, information on the relative fluxes and spectral shapes of the different ion species over these energy ranges is lacking. However, new observations from the Energetic Ion Spectrometer (EIS) instruments on the Magnetospheric Multiscale (MMS) spacecraft have revealed the dominance of heavy ion species (specifically oxygen and helium) at these energies in the outer magnetosphere. This result is supported by prior but previously unreported observations obtained by the Geotail spacecraft, which also show that these heavy ion species are primarily dominated by multiply-charged populations from the solar wind. Using additional observations from the inner magnetosphere obtained by the RBSPICE instrument on the Van Allen Probes suggest, we will investigate whether this effect is due to a preferential loss of protons in the outer magnetosphere.

  4. INERTIAL FUSION DRIVEN BY INTENSE HEAVY-ION BEAMS

    SciTech Connect

    Sharp, W. M.; Friedman, A.; Grote, D. P.; Barnard, J. J.; Cohen, R. H.; Dorf, M. A.; Lund, S. M.; Perkins, L. J.; Terry, M. R.; Logan, B. G.; Bieniosek, F. M.; Faltens, A.; Henestroza, E.; Jung, J. Y.; Kwan, J. W.; Lee, E. P.; Lidia, S. M.; Ni, P. A.; Reginato, L. L.; Roy, P. K.; Seidl, P. A.; Takakuwa, J. H.; Vay, J.-L.; Waldron, W. L.; Davidson, R. C.; Gilson, E. P.; Kaganovich, I. D.; Qin, H.; Startsev, E.; Haber, I.; Kishek, R. A.; Koniges, A. E.

    2011-03-31

    Intense heavy-ion beams have long been considered a promising driver option for inertial-fusion energy production. This paper briefly compares inertial confinement fusion (ICF) to the more-familiar magnetic-confinement approach and presents some advantages of using beams of heavy ions to drive ICF instead of lasers. Key design choices in heavy-ion fusion (HIF) facilities are discussed, particularly the type of accelerator. We then review experiments carried out at Lawrence Berkeley National Laboratory (LBNL) over the past thirty years to understand various aspects of HIF driver physics. A brief review follows of present HIF research in the US and abroad, focusing on a new facility, NDCX-II, being built at LBNL to study the physics of warm dense matter heated by ions, as well as aspects of HIF target physics. Future research directions are briefly summarized.

  5. Ultra-relativistic heavy ions and cosmic rays

    NASA Astrophysics Data System (ADS)

    McLerran, L.

    1983-05-01

    The collisions of ultra-relativistic heavy ions, E/sub /N/ greater than or equal to 1 TeV/nucleon are most interesting, since, at these energies, matter is produced at a sufficiently high energy density that a quark-gluon plasma has a good chance to form. Very heavy ions are also most interesting since the matter forms in a larger volume than for light ions, and the matter is at a somewhat higher density. At very high energies with very heavy ions there is great flexibility in the experimental signals which might be studied, as well as the nature of the matter which is produced. The fragmentation region and central region provide different environments where a plasma might form. The former is baryon rich while the central region is high temperature with low baryon number density and is not accessible except at very high energies.

  6. Characterizing the Energetic Heavy Ion Environment Inside 4 Jovian Radii

    NASA Astrophysics Data System (ADS)

    Cohen, C. M.; Stone, E. C.

    2004-05-01

    On 21 September 2003 Galileo impacted Jupiter to end its 8-year tour of the Jovian magentosphere. During this last phase data was collected in the very inner part of the magnetosphere at distances < 4 Rj. The region from 2 to 4 Rj was previously explored by Galileo during its 34th orbit around Jupiter. We present the combined data from these two passes obtained by the Heavy Ion Counter (HIC) for heavy ions at energies above 2 MeV/nucleon. In particular we discuss the significant ion absorption near the moons Thebe and Amalthea, the anisotropic pitch angle distribution and the dramatic increase in heavy ion intensity with decreasing radius seen in this region

  7. Ultra-relativistic heavy ions and cosmic rays

    SciTech Connect

    McLerran, L.

    1983-05-01

    The collisions of ultra-relativistic heavy ions, E/sub /N/ greater than or equal to 1 TeV/nucleon are most interesting, since, at these energies, matter is produced at sufficiently high energy density that a quark-gluon plasma has a good chance to form. Very heavy ions are also most interesting since the matter forms in a larger volume than for light ions, and the matter is at a somewhat higher energy density. At very high energies with very heavy ions there is great flexibility in the experimental signals which might be studied, as well as the nature of the matter which is produced. The fragmentation region and central region provide different environments where a plasma might form. The former is baryon rich while the central region is high temperature with low baryon number density and is not accessible except at very high energies.

  8. Ultra-relativistic heavy ions and the CBA

    SciTech Connect

    McLerran, L.D.

    1982-01-01

    The study of ultra-relativistic heavy ions at an accelerator such as the CBA provides a unique glimpse of matter as it may have appeared in the early universe. This hot dense matter very probably appears as a quark-gluon plasma which expands and cools into hadronic matter. The CBA would provide data at the very highest energies, and produce matter at the highest energy densities. The possibility of using a cyclotron to inject very heavy ions into the AGS and then into the CBA would also allow the production of quark-gluon matter at higher energy densities than would light ions, and would make the matter in a larger volume where surface effects are minimized. At the highest energies with very heavy ions, there is great flexibility in the experimental signals which might be studied, as well as the nature of the matter which is produced. Some of the possibilities are discussed. (WHK)

  9. High-Resolution Ambient MS Imaging of Negative Ions in Positive Ion Mode: Using Dicationic Reagents with the Single-Probe

    NASA Astrophysics Data System (ADS)

    Rao, Wei; Pan, Ning; Tian, Xiang; Yang, Zhibo

    2016-01-01

    We have used the Single-probe, a miniaturized sampling device utilizing in-situ surface microextraction for ambient mass spectrometry (MS) analysis, for the high resolution MS imaging (MSI) of negatively charged species in the positive ionization mode. Two dicationic compounds, 1,5-pentanediyl-bis(1-butylpyrrolidinium) difluoride [C5(bpyr)2F2] and 1,3-propanediyl-bis(tripropylphosphonium) difluoride [C3(triprp)2F2], were added into the sampling solvent to form 1+ charged adducts with the negatively charged species extracted from tissues. We were able to detect 526 and 322 negatively charged species this way using [C5(bpyr)2F2] and [C3(triprp)2F2], respectively, including oleic acid, arachidonic acid, and several species of phosphatidic acid, phosphoethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, and others. In conjunction with the identification of the non-adduct cations, we have tentatively identified a total number of 1200 and 828 metabolites from mouse brain sections using [C5(bpyr)2F2] and [C3(triprp)2F2], respectively, through high mass accuracy measurements (mass error <5 ppm); MS/MS analyses were also performed to verify the identity of selected species. In addition to the high mass accuracy measurement, we were able to generate high spatial resolution (~17 μm) MS images of mouse brain sections. Our study demonstrated that utilization of dicationic compounds in the surface microextraction with the Single-probe device can perform high mass and spatial resolution ambient MSI measurements of broader types of compounds in tissues. Other reagents can be potentially used with the Single-probe device for a variety of reactive MSI studies to enable the analysis of species that are previously intractable.

  10. ECR (electron cyclotron resonance) ion sources and applications with heavy-ion linacs

    SciTech Connect

    Pardo, R.C.

    1990-01-01

    The electron cyclotron resonance (ECR) ion source has been developed in the last few years into a reliable source of high charge-state heavy ions. The availability of heavy ions with relatively large charge-to-mass ratios (0.1--0.5) has made it possible to contemplate essentially new classes of heavy-ion linear accelerators. In this talk, I shall review the state-of-the-art in ECR source performance and describe some of the implications this performance level has for heavy-ion linear accelerator design. The present linear accelerator projects using ECR ion sources will be noted and the performance requirements of the ECR source for these projects will be reviewed. 30 refs., 3 figs.

  11. Scanning electrochemical cell microscopy: theory and experiment for quantitative high resolution spatially-resolved voltammetry and simultaneous ion-conductance measurements.

    PubMed

    Snowden, Michael E; Güell, Aleix G; Lai, Stanley C S; McKelvey, Kim; Ebejer, Neil; O'Connell, Michael A; Colburn, Alexander W; Unwin, Patrick R

    2012-03-06

    Scanning electrochemical cell microscopy (SECCM) is a high resolution electrochemical scanning probe technique that employs a dual-barrel theta pipet probe containing electrolyte solution and quasi-reference counter electrodes (QRCE) in each barrel. A thin layer of electrolyte protruding from the tip of the pipet ensures that a gentle meniscus contact is made with a substrate surface, which defines the active surface area of an electrochemical cell. The substrate can be an electrical conductor, semiconductor, or insulator. The main focus here is on the general case where the substrate is a working electrode, and both ion-conductance measurements between the QRCEs in the two barrels and voltammetric/amperometric measurements at the substrate can be made simultaneously. In usual practice, a small perpendicular oscillation of the probe with respect to the substrate is employed, so that an alternating conductance current (ac) develops, due to the change in the dimensions of the electrolyte contact (and hence resistance), as well as the direct conductance current (dc). It is shown that the dc current can be predicted for a fixed probe by solving the Nernst-Planck equation and that the ac response can also be derived from this response. Both responses are shown to agree well with experiment. It is found that the pipet geometry plays an important role in controlling the dc conductance current and that this is easily measured by microscopy. A key feature of SECCM is that mass transport to the substrate surface is by diffusion and, for charged analytes, ion migration which can be controlled and varied quantifiably via the bias between the two QRCEs. For a working electrode substrate this means that charged redox-active analytes can be transported to the electrode/solution interface in a well-defined and controllable manner and that relatively fast heterogeneous electron transfer kinetics can be studied. The factors controlling the voltammetric response are determined by

  12. Clinical trial of cancer therapy with heavy ions at heavy ion research facility in lanzhou

    NASA Astrophysics Data System (ADS)

    Zhang, Hong

    With collaborative efforts of scientists from the Institute of Modern Physics (IMP), Chinese Academy of Sciences and hospitals in Gansu, initial clinical trial on cancer therapy with heavy ions has been successfully carried out in China. From November 2006 to December 2007, 51 patients with superficially-placed tumors were treated with carbon ions at Heavy Ion Research Facility in Lanzhou (HIRFL) within four beam time blocks of 6-11 days, collaborating with the General Hospital of Lanzhou Command and the Tumor Hospital of Gansu Province. Patients and Methods: There were 51 patients (31 males and 20 females) with superficially-placed tumors (squamous cell carcinoma of the skin, basal cell carcinoma of the skin, malignant skin melanoma, sarcoma, lymphoma, breast cancer, metastatic lymph nodes of carcinomas and other skin lesions). The tumors were less than 2.1 cm deep to the skin surface. All patients had histological confirmation of their tumors. Karnofsky Performance Scale (KPS) of all patients was more than 70. The majority of patients were with failures or recurrences of conventional therapies. Median age at the time of radiotherapy (RT) was 55.5 years (range 5-85 years). Patients were immobilized with a vacuum cushion or a head mask and irradiated by carbon ion beams with energy 80-100 MeV/u at spread-out Bragg peak field generated from HIRFL, with two and three-dimensional conformal irradiation methods. Target volume was defined by physical palpation [ultrasonography and Computerized tomography (CT), for some cases]. The clinical target volume (CTV) was defined as the gross total volume GTV with a 0.5-1.0cm margin axially. Field placement for radiation treatment planning was done based on the surface markings. RBE of 2.5-3 within the target volume, and 40-75 GyE with a weekly fractionation of 7 × 3-15 GyE/fraction were used in the trial. Patients had follow-up examinations performed 1 month after treatment, in 1 or 2 months for the first 6 months, and 3

  13. On the amount of heavy molecular ions in Titan's ionosphere

    NASA Astrophysics Data System (ADS)

    Wahlund, J.-E.; Galand, M.; Müller-Wodarg, I.; Cui, J.; Yelle, R. V.; Crary, F. J.; Mandt, K.; Magee, B.; Waite, J. H.; Young, D. T.; Coates, A. J.; Garnier, P.; Ågren, K.; André, M.; Eriksson, A. I.; Cravens, T. E.; Vuitton, V.; Gurnett, D. A.; Kurth, W. S.

    2009-12-01

    We present observational evidence that the ionosphere of Titan below an altitude of 1150 km is a significant source of heavy (>100 amu) molecular organic species. This study is based on measurements by five instruments (RPWS/LP, RPWS/E, INMS, CAPS/ELS, CAPS/IBS) onboard the Cassini spacecraft during three flybys (T17, T18, T32) of Titan. The ionospheric peaks encountered at altitudes of 950-1300 km had densities in the range 900-3000 cm -3. Below these peaks the number densities of heavy positively charged ions reached 100-2000 cm -3 and approached 50-70% of the total ionospheric density with an increasing trend toward lowest measured altitudes. Simultaneously measured negatively charged ion densities were in the range 50-150 cm -3. These results imply that ~10 5-10 6 heavy positively charged ions/m 3/s are continuously recombining into heavy neutrals and supply the atmosphere of Titan. The ionosphere may in this way produce 0.1-1 Mt/yr of heavy organic compounds and is therefore a sizable source for aerosol formation. We also predict that Titan's ionosphere is dominated by heavy (>100 amu) molecular ions below 950 km.

  14. Molecular dynamics simulations of ion range profiles for heavy ions in light targets

    SciTech Connect

    Lan, Chune; Xue, Jianming; Zhang, Yanwen; Morris, James R.; Zhu, Zihua; Gao, Yuan; Wang, Yugang; Yan, Sha; Weber, William J.

    2012-09-01

    The determination of stopping powers for slow heavy ions in targets containing light elements is important to accurately describe ion-solid interactions, evaluate ion irradiation effects and predict ion ranges for device fabrication and nuclear applications. Recently, discrepancies of up to 40% between the experimental results and SRIM (Stopping and Range of Ions in Matter) predictions of ion ranges for heavy ions with medium and low energies (<25 keV/nucleon) in light elemental targets have been reported. The longer experimental ion ranges indicate that the stopping powers used in the SRIM code are overestimated. Here, a molecular dynamics simulation scheme is developed to calculate the ion ranges of heavy ions in light elemental targets. Electronic stopping powers generated from both a reciprocity approach and the SRIM code are used to investigate the influence of electronic stopping on ion range profiles. The ion range profiles for Au and Pb ions in SiC and Er ions in Si, with energies between 20 and 5250 keV, are simulated. The simulation results show that the depth profiles of implanted ions are deeper and in better agreement with the experiments when using the electronic stopping power values derived from the reciprocity approach. These results indicate that the origin of the discrepancy in ion ranges between experimental results and SRIM predictions in the low energy region may be an overestimation of the electronic stopping powers used in SRIM.

  15. Molecular dynamics simulations of ion range profiles for heavy ions in light targets

    SciTech Connect

    Lan, Chune; Xue, Jianming; Zhang, Yanwen; Morris, James R; Zhu, Zihua; Gao, Yuan; Wang, Yugang; Yan, Sha; Weber, William J

    2012-01-01

    The determination of stopping powers for slow heavy ions in targets containing light elements is important to accurately describe ion-solid interactions, evaluate ion irradiation effects and predict ion ranges for device fabrication and nuclear applications. Recently, discrepancies of up to 40% between the experimental results and SRIM (Stopping and Range of Ions in Matter) predictions of ion ranges for heavy ions with medium and low energies (< {approx} 25 keV/nucleon) in light elemental targets have been reported. The longer experimental ion ranges indicate that the stopping powers used in the SRIM code are overestimated. Here, a molecular dynamics simulation scheme is developed to calculate the ion ranges of heavy ions in light elemental targets. Electronic stopping powers generated from both a reciprocity approach and the SRIM code are used to investigate the influence of electronic stopping on ion range profiles. The ion range profiles for Au and Pb ions in SiC and Er ions in Si, with energies between 20 and 5250 keV, are simulated. The simulation results show that the depth profiles of implanted ions are deeper and in better agreement with the experiments when using the electronic stopping power values derived from the reciprocity approach. These results indicate that the origin of the discrepancy in ion ranges between experimental results and SRIM predictions in the low energy region may be an overestimation of the electronic stopping powers used in SRIM.

  16. Heavy-ion tumor therapy: Physical and radiobiological benefits

    NASA Astrophysics Data System (ADS)

    Schardt, Dieter; Elsässer, Thilo; Schulz-Ertner, Daniela

    2010-01-01

    High-energy beams of charged nuclear particles (protons and heavier ions) offer significant advantages for the treatment of deep-seated local tumors in comparison to conventional megavolt photon therapy. Their physical depth-dose distribution in tissue is characterized by a small entrance dose and a distinct maximum (Bragg peak) near the end of range with a sharp fall-off at the distal edge. Taking full advantage of the well-defined range and the small lateral beam spread, modern scanning beam systems allow delivery of the dose with millimeter precision. In addition, projectiles heavier than protons such as carbon ions exhibit an enhanced biological effectiveness in the Bragg peak region caused by the dense ionization of individual particle tracks resulting in reduced cellular repair. This makes them particularly attractive for the treatment of radio-resistant tumors localized near organs at risk. While tumor therapy with protons is a well-established treatment modality with more than 60 000 patients treated worldwide, the application of heavy ions is so far restricted to a few facilities only. Nevertheless, results of clinical phase I-II trials provide evidence that carbon-ion radiotherapy might be beneficial in several tumor entities. This article reviews the progress in heavy-ion therapy, including physical and technical developments, radiobiological studies and models, as well as radiooncological studies. As a result of the promising clinical results obtained with carbon-ion beams in the past ten years at the Heavy Ion Medical Accelerator facility (Japan) and in a pilot project at GSI Darmstadt (Germany), the plans for new clinical centers for heavy-ion or combined proton and heavy-ion therapy have recently received a substantial boost.

  17. Heavy-ion tumor therapy: Physical and radiobiological benefits

    SciTech Connect

    Schardt, Dieter; Elsaesser, Thilo; Schulz-Ertner, Daniela

    2010-01-15

    High-energy beams of charged nuclear particles (protons and heavier ions) offer significant advantages for the treatment of deep-seated local tumors in comparison to conventional megavolt photon therapy. Their physical depth-dose distribution in tissue is characterized by a small entrance dose and a distinct maximum (Bragg peak) near the end of range with a sharp fall-off at the distal edge. Taking full advantage of the well-defined range and the small lateral beam spread, modern scanning beam systems allow delivery of the dose with millimeter precision. In addition, projectiles heavier than protons such as carbon ions exhibit an enhanced biological effectiveness in the Bragg peak region caused by the dense ionization of individual particle tracks resulting in reduced cellular repair. This makes them particularly attractive for the treatment of radio-resistant tumors localized near organs at risk. While tumor therapy with protons is a well-established treatment modality with more than 60 000 patients treated worldwide, the application of heavy ions is so far restricted to a few facilities only. Nevertheless, results of clinical phase I-II trials provide evidence that carbon-ion radiotherapy might be beneficial in several tumor entities. This article reviews the progress in heavy-ion therapy, including physical and technical developments, radiobiological studies and models, as well as radiooncological studies. As a result of the promising clinical results obtained with carbon-ion beams in the past ten years at the Heavy Ion Medical Accelerator facility (Japan) and in a pilot project at GSI Darmstadt (Germany), the plans for new clinical centers for heavy-ion or combined proton and heavy-ion therapy have recently received a substantial boost.

  18. Microirradiation of cells with energetic heavy ions

    NASA Astrophysics Data System (ADS)

    Dollinger, G.; Hable, V.; Hauptner, A.; Krücken, R.; Reichart, P.; Friedl, A. A.; Drexler, G.; Cremer, T.; Dietzel, S.

    2005-04-01

    The ion microprobe SNAKE (superconducting nanoscope for applied nuclear (Kern) physics experiments) at the Munich 14 MV tandem accelerator achieves beam focusing by a superconducting quadrupole doublet and can make use of a broad range of ions and ion energies, from 20 MeV protons to 200 MeV gold ions. This allows to adjust the number of DNA single strand breaks (SSBs) and double strand breaks (DSBs) per ion and per cell nucleus from about 0.1 DSBs per ion to several 100 DSBs per ion. When irradiating with single 100 MeV 16O ions, the adapted setup permits a fwhm irradiation accuracy of 0.55 μm in x-direction and 0.4 μm in y-direction, as demonstrated by retrospective track etching of polycarbonate foils. The experiments point to investigate protein dynamics after targeted irradiation. As an example for such experiments we show a kind of three dimensional representation of foci of γ-H2AX which are visible 0.5 h after the irradiation with 100 MeV 16O ions took place. It shows the gross correlation with the irradiation pattern but also distinct deviations which are attributed to protein dynamics in the cell.

  19. Coolwater culmination: Sensitive high-resolution ion microprobe (SHRIMP) U-Pb and isotopic evidence for continental delamination in the Syringa Embayment, Salmon River suture, Idaho

    USGS Publications Warehouse

    Lund, K.; Aleinikoff, J.N.; Yacob, E.Y.; Unruh, D.M.; Fanning, C.M.

    2008-01-01

    During dextral oblique translation along Laurentia in western Idaho, the Blue Mountains superterrane underwent clockwise rotation and impinged into the Syringa embayment at the northern end of the Salmon River suture. Along the suture, the superterrane is juxtaposed directly against western Laurentia, making this central Cordilleran accretionary-margin segment unusually attenuated. In the embayment, limited orthogonal contraction produced a crustal wedge of oceanic rocks that delaminated Laurentian crust. The wedge is exposed through Laurentian crust in the Coolwater culmination as documented by mapping and by sensitive high-resolution ion microprobe U-Pb, Sri, and ??Nd data for gneisses that lie inboard of the suture. The predominant country rock is Mesoproterozoic paragneiss overlying Laurentian basement. An overlying Neoproterozoic (or younger) paragneiss belt in the Syringa embayment establishes the form of the Cordilleran miogeocline and that the embayment is a relict of Rodinia rifting. An underlying Cretaceous paragneiss was derived from arc terranes and suture-zone orogenic welt but also from Laurentia. The Cretaceous paragneiss and an 86-Ma orthogneiss that intruded it formed the wedge of oceanic rocks that were inserted into the Laurentian margin between 98 and 73 Ma, splitting supracrustal Laurentian rocks from their basement. Crustal thickening, melting and intrusion within the wedge, and folding to form the Coolwater culmination continued until 61 Ma. The embayment formed a restraining bend at the end of the dextral transpressional suture. Clockwise rotation of the impinging superterrane and overthrusting of Laurentia that produced the crustal wedge in the Coolwater culmination are predicted by oblique collision into the Syringa embayment. Copyright 2008 by the American Geophysical Union.

  20. Laboratory and Ambient Measurements of Oxidized Organic Compounds in the Gas Phase Using Nitrate Ion Chemical Ionization Coupled with High Resolution Time-of-Flight Mass Spectrometry

    NASA Astrophysics Data System (ADS)

    Massoli, P.; Stark, H.; Canagaratna, M. R.; Krechmer, J.; Lambe, A. T.; Isaacman-VanWertz, G. A.; Nowak, J. B.; Kimmel, J.; Kroll, J. H.; Jayne, J. T.; Worsnop, D. R.

    2015-12-01

    Chemical Ionization Mass Spectrometry (CIMS) is a widely used technique for molecular level characterization of inorganic and organic gas phase species. Here we present laboratory and ambient measurements of gaseous organic compounds by means of a High Resolution Time-of-Flight Chemical Ionization Mass Spectrometry (HR-ToF-CIMS) using nitrate ion (NO3-) chemistry, which recently has proven capable of selectively detecting oxidized organic molecules in the gas-phase via clustering with NO3- and its high order clusters. Such low and extremely low volatility organic compounds (LVOC, ELVOC) have an important role in particulate phase chemistry and formation of secondary organic aerosol (SOA). The HR-ToF-CIMS was deployed during the Southern Oxidant and Aerosol Study (SOAS) at the forest site in Centreville, AL (June 1 - July 15, 2013), where emissions were dominated by biogenic volatile organic compounds (BVOC), occasionally mixing with anthropogenic emissions. During SOAS, the HR-ToF-CIMS detected oxidation products of both isoprene (typically C5 LVOC) and terpenes (typically C10 ELVOC). The isoprene-related LVOC showed a diurnal cycle with a day time peak, while two groups of terpene ELVOC were identified, one peaking at night and one peaking during the day. Positive Matrix Factorization (PMF) analyses are applied to the dataset to further interpret these observations. The effect of anthropogenic pollution on the biogenic-dominated environment was also investigated during periods of elevated nitrous and sulfur dioxide levels. To further aid in interpretation of the SOAS dataset, oxidized organic molecules were produced via OH and O3 initiated oxidation of biogenic gas-phase precursors in targeted laboratory studies and detected using the HR-ToF-CIMS. Spectra were obtained in these studies over a range of simulated atmospheric conditions.

  1. Neoproterozoic backarc basin: Sensitive high-resolution ion microprobe U-Pb and Sm-Nd isotopic evidence from the Eastern Pampean Ranges, Argentina

    NASA Astrophysics Data System (ADS)

    Escayola, Mónica P.; Pimentel, Márcio M.; Armstrong, Richard

    2007-06-01

    The Eastern Pampean Ranges comprise high-grade supracrustal sequences with linear belts of mafic-ultramafic bodies representing ophiolite remnants. New U-Pb and Nd isotopic data suggest that the tectonic evolution of the Pampean Ranges started ca. 640 Ma with the deposition of supracrustal sequences in a backarc basin between a Neoproterozoic magmatic arc to the east and the Pampia terrane to the west. Ophiolite remnants of this backarc basin yielded a whole-rock isochron indicating the age of 647 ± 77 Ma (2σ) and ɛNd (initial time [T]) of +5.2. Sensitive high-resolution ion microprobe U-Pb data for detrital metasediments show provenance patterns with two main age populations: the older 1.1-0.9 Ga, and the younger between ca. 0.7 and 0.6 Ga. The Neoproterozoic population is relatively more abundant in sediments of the easternmost units of the Eastern Pampean Ranges and becomes less abundant toward the west. Depleted mantle ages show a similar pattern, with ages generally increasing from east (1.42 Ga) to west (1.76 Ga), suggesting the presence of Neo-proterozoic sources to the east of the ranges. The provenance data do not support previous evolution models for the Eastern Pampean Ranges, according to which the supracrustal sequence represents the passive margin of the Río de la Plata craton. Early Cambrian collision and high-grade metamorphism mark the final stages of evolution of the belt and were shortly followed by calc-alkaline metaluminous and peraluminous granitic magmatism ca. 530-514 Ma. The results suggest that the geological evolution of the Eastern Pampean Ranges took place between ca. 640 and 514 Ma, coeval with other Brasiliano orogens in Brazil (e.g., the Paraguay and Araguaia fold belts).

  2. U-Pb sensitive high-resolution ion microprobe (SHRIMP) zircon geochronology of granitoid rocks in eastern Zambia: Terrane subdivision of the Mesoproterozoic Southern Irumide Belt

    NASA Astrophysics Data System (ADS)

    Johnson, S. P.; de Waele, B.; Liyungu, K. A.

    2006-12-01

    The Southern Irumide Belt (SIB) is a structurally and metamorphically complex region of mainly Mesoproterozoic igneous rocks in southern and eastern Zambia, northern Mozambique and northern Malawi that was strongly overprinted in the Neoproterozoic to Cambrian Damara-Lufilian-Zambezi (DLZ) orogeny. Because of the scarcity of geological data from this region, little is known about the timing of tectonomagmatic events; however, this belt has traditionally been considered to be a southerly continuation of the adjacent Irumide Belt (IB). Here we provide 27 new U-Pb sensitive high-resolution ion microprobe (SHRIMP) zircon ages that constrain the Paleoproterozoic to Cambrian tectonomagmatic history of this belt and which, for the first time, allow for direct comparison with the adjoining IB. The SIB is floored by a predominantly late Paleoproterozoic basement, which was intruded by voluminous continental margin arc-related magmas between 1.09 and 1.04 Ga and accompanied by high-temperature/low-pressure metamorphism. In contrast, the IB is floored by a late Paleoproterozoic basement that is generally older than 2.0 Ga, contains significant mid-Mesoproterozoic plutonic rocks that are not present within the SIB, and underwent moderate-pressure/moderate-temperature compressional metamorphism and S-type granitoid magmatism at circa 1.02 Ga. These data indicate that the crust underlying the SIB is not a continuation of that underlying the IB but represents an allocthonous continental margin arc terrane juxtaposed against the Congo-Tanzania-Bangweulu Craton during the late Mesoproterozoic Irumide orogeny. Reworking and shearing of the SIB occurred during the DLZ orogen, resulting in the present-day architecture as a series of stacked terranes which have been exploited by voluminous posttectonic granitoid batholiths.

  3. Simultaneous quantification of amino acids and Amadori products in foods through ion-pairing liquid chromatography-high-resolution mass spectrometry.

    PubMed

    Troise, Antonio Dario; Fiore, Alberto; Roviello, Giovanni; Monti, Simona Maria; Fogliano, Vincenzo

    2015-01-01

    The formation of the Amadori products (APs) is the first key step of Maillard reaction. Only few papers have dealt with simultaneous quantitation of amino acids and corresponding APs (1-amino-1-deoxy-2-ketose). Chromatographic separation of APs is affected by several drawbacks mainly related to their poor retention in conventional reversed phase separation. In this paper, a method for the simultaneous quantification of amino acids and their respective APs was developed combining high-resolution mass spectrometry with ion-pairing liquid chromatography. The limit of detection was 0.1 ng/mL for tryptophan, valine and arginine, while the limit of quantification ranged from 2 to 5 ng/mL according to the specific sensitivity of each analyte. The relative standard deviation % was lower than 10 % and the coefficient of correlation was higher than 0.99 for each calibration curve. The method was applied to milk, milk-based products, raw and processed tomato. Among the analyzed products, the most abundant amino acid was glutamic acid (16,646.89 ± 1,385.40 µg/g) and the most abundant AP was fructosyl-arginine in tomato puree (774.82 ± 10.01 µg/g). The easiness of sample preparation coupled to the analytical performances of the proposed method introduced the possibility to use the pattern of free amino acids and corresponding APs in the evaluation of the quality of raw food as well as the extent of thermal treatments in different food products.

  4. Geometrical methods in heavy ion collisions

    NASA Astrophysics Data System (ADS)

    Taliotis, Anastasios

    Currently there exists no known way to construct the Stress-Energy tensor (Tmunu) of the medium produced in heavy ion collisions at strong coupling from purely theoretical grounds. In this work, some steps are taken in that direction. In particular, the evolution of Tmunu at strong coupling and at high energies is being studied for early proper times (tau). This is achieved in the context of the AdS/CFT duality by constructing the evolution of the dual geometry in an AdS5 background. We consider high energy collisions of two shock waves in AdS5 as a model of ultra-relativistic nucleus-nucleus collisions in the boundary theory. We first calculate the graviton field produced in the collisions in the LO, NLO and NNLO approximations, corresponding to two, three and four-graviton exchanges with the shock waves. We use this model to study Tmunu and in particular the energy density of the strongly-coupled matter created immediately after the collision because as we argue, the expansion of the energy density (epsilon) in the powers of proper time tau squared corresponds on the gravity side to a perturbative expansion of the metric in graviton exchanges. We point out that shock waves corresponding to physical energy-momentum tensors of the nuclei is likely to completely stop after the collision; on the field theory side, this corresponds to complete nuclear stopping due to strong coupling effects, likely leading to Landau hydrodynamics. This motivates a more detailed investigation. For this reason we consider the asymmetric limit where the energy density in one shock wave is much higher than in the other one. In the boundary theory this setup corresponds to proton-nucleus collisions. Employing the eikonal approximation we find the exact high energy analytic solution for the metric in AdS5 for the asymmetric collision of two delta-function shock waves. The solution resums all-order graviton exchanges with the nucleus-shock wave and a single-graviton exchange with the proton

  5. High-resolution headlamp

    NASA Astrophysics Data System (ADS)

    Gut, Carsten; Cristea, Iulia; Neumann, Cornelius

    2016-04-01

    The following article shall describe how human vision by night can be influenced. At first, front lighting systems that are already available on the market will be described, followed by their analysis with respect to the positive effects on traffic safety. Furthermore, how traffic safety by night can be increased since the introduction of high resolution headlamps shall be discussed.

  6. Anti-biofilm activity of Fe heavy ion irradiated polycarbonate

    NASA Astrophysics Data System (ADS)

    Joshi, R. P.; Hareesh, K.; Bankar, A.; Sanjeev, Ganesh; Asokan, K.; Kanjilal, D.; Dahiwale, S. S.; Bhoraskar, V. N.; Dhole, S. D.

    2016-10-01

    Polycarbonate (PC) polymers were investigated before and after high energy heavy ion irradiation for anti-bacterial properties. These PC films were irradiated by Fe heavy ions with two energies, viz, 60 and 120 MeV, at different fluences in the range from 1 × 1011 ions/cm2 to 1 × 1013 ions/cm2. UV-Visible spectroscopic results showed optical band gap decreased with increase in ion fluences due to chain scission mainly at carbonyl group of PC which is also corroborated by Fourier transform infrared spectroscopic results. X-ray diffractogram results showed decrease in crystallinity of PC after irradiation which leads to decrease in molecular weight. This is confirmed by rheological studies and also by differential scanning calorimetric results. The irradiated PC samples showed modification in their surfaces prevents biofilm formation of human pathogen, Salmonella typhi.

  7. Advances in U.S. Heavy Ion Fusion Science

    SciTech Connect

    Logan, B.G.; Barnard, J.J.; Bieniosek, F.M.; Cohen, R.H.; Coleman, J.E.; Davidson, R.C.; Efthimion, P.C.; Friedman, A.; Gilson, E.P.; Grisham, L.R.; Grote, D.P.; Henestroza, E.; Kaganovich, I.D.; Kireeff-Covo, M.; Lee, E.P.; Leitner, M.A.; Lund, S.M.; Molvik, A.W.; Ni, P.; Perkins, L. J.; Qin, H.; Roy, P.K.; Sefkow, A.B.; Seidl, P.A.; Startsev, E.A.; Waldron, W.L.

    2007-09-01

    During the past two years, the US heavy ion fusion science program has made significant experimental and theoretical progress in simultaneous transverse and longitudinal beam compression, ion-beam-driven warm dense matter targets, high-brightness beam transport, advanced theory and numerical simulations, and heavy ion target physics for fusion. First experiments combining radial and longitudinal compression {pi} of intense ion beams propagating through background plasma resulted in on-axis beam densities increased by 700X at the focal plane. With further improvements planned in 2008, these results enable initial ion beam target experiments in warm dense matter to begin next year. They are assessing how these new techniques apply to higher-gain direct-drive targets for inertial fusion energy.

  8. Advances in U.S. Heavy Ion Fusion Science

    SciTech Connect

    Barnard, JJ; Logan, B.G.; Barnard, J.J.; Bieniosek, F.M.; Cohen, R.H.; Coleman, J.E.; Davidson, R.C.; Efthimion, P.C.; Friedman, A.; Gilson, E.P.; Grisham, L.R.; Grote, D.P.; Henestroza, E.; Kaganovich, I.D.; Kireeff-Covo, M.; Lee, E.P.; Leitner, M.A.; Lund, S.M.; Molvik, A.W.; Ni, P.; Perkins, L.J.; Qin, H.; Roy, P.K.; Sefkow, A.B.; Seidl, P.A.; Startsev, E.A.; Waldron, W.L.

    2007-09-03

    During the past two years, the US heavy ion fusion science program has made significant experimental and theoretical progress in simultaneous transverse and longitudinal beam compression, ion-beam-driven warm dense matter targets, high-brightness beam transport, advanced theory and numerical simulations, and heavy ion target physics for fusion. First experiments combining radial and longitudinal compression {pi} of intense ion beams propagating through background plasma resulted in on-axis beam densities increased by 700X at the focal plane. With further improvements planned in 2008, these results enable initial ion beam target experiments in warm dense matter to begin next year. They are assessing how these new techniques apply to higher-gain direct-drive targets for inertial fusion energy.

  9. Inferring Magnetospheric Heavy Ion Density using EMIC Waves

    SciTech Connect

    Kim, Eun-Hwa; Johnson, Jay R.; Kim, Hyomin; Lee, Dong-Hun

    2014-05-01

    We present a method to infer heavy ion concentration ratios from EMIC wave observations that result from ionion hybrid (IIH) resonance. A key feature of the ion-ion hybrid resonance is the concentration of wave energy in a field-aligned resonant mode that exhibits linear polarization. This mode converted wave is localized at the location where the frequency of a compressional wave driver matches the IIH resonance condition, which depends sensitively on the heavy ion concentration. This dependence makes it possible to estimate the heavy ion concentration ratio. In this letter, we evaluate the absorption coefficients at the IIH resonance at Earth's geosynchronous orbit for variable concentrations of He+ and field-aligned wave numbers using a dipole magnetic field. Although wave absorption occurs for a wide range of heavy ion concentrations, it only occurs for a limited range of field-aligned wave numbers such that the IIH resonance frequency is close to, but not exactly the same as the crossover frequency. Using the wave absorption and observed EMIC waves from GOES-12 satellite, we demonstrate how this technique can be used to estimate that the He+ concentration is around 4% near L = 6.6.

  10. Detection of atmospheric gaseous amines and amides by a high-resolution time-of-flight chemical ionization mass spectrometer with protonated ethanol reagent ions

    NASA Astrophysics Data System (ADS)

    Yao, Lei; Wang, Ming-Yi; Wang, Xin-Ke; Liu, Yi-Jun; Chen, Hang-Fei; Zheng, Jun; Nie, Wei; Ding, Ai-Jun; Geng, Fu-Hai; Wang, Dong-Fang; Chen, Jian-Min; Worsnop, Douglas R.; Wang, Lin

    2016-11-01

    Amines and amides are important atmospheric organic-nitrogen compounds but high time resolution, highly sensitive, and simultaneous ambient measurements of these species are rather sparse. Here, we present the development of a high-resolution time-of-flight chemical ionization mass spectrometer (HR-ToF-CIMS) method, utilizing protonated ethanol as reagent ions to simultaneously detect atmospheric gaseous amines (C1 to C6) and amides (C1 to C6). This method possesses sensitivities of 5.6-19.4 Hz pptv-1 for amines and 3.8-38.0 Hz pptv-1 for amides under total reagent ion signals of ˜ 0.32 MHz. Meanwhile, the detection limits were 0.10-0.50 pptv for amines and 0.29-1.95 pptv for amides at 3σ of the background signal for a 1 min integration time. Controlled characterization in the laboratory indicates that relative humidity has significant influences on the detection of amines and amides, whereas the presence of organics has no obvious effects. Ambient measurements of amines and amides utilizing this method were conducted from 25 July to 25 August 2015 in urban Shanghai, China. While the concentrations of amines ranged from a few parts per trillion by volume to hundreds of parts per trillion by volume, concentrations of amides varied from tens of parts per trillion by volume to a few parts per billion by volume. Among the C1- to C6-amines, the C2-amines were the dominant species with concentrations up to 130 pptv. For amides, the C3-amides (up to 8.7 ppb) were the most abundant species. The diurnal and backward trajectory analysis profiles of amides suggest that in addition to the secondary formation of amides in the atmosphere, industrial emissions could be important sources of amides in urban Shanghai. During the campaign, photo-oxidation of amines and amides might be a main loss pathway for them in daytime, and wet deposition was also an important sink.

  11. High resolution mesurements of 18O/16O ratios of present and fossil herbivores dental enamel using the ims 1270 ion microprobe

    NASA Astrophysics Data System (ADS)

    Pisapia, C.; Bentaleb, I.; Rollion-Bard, C.; Tafforeau, P.; Fontugne, M.; France-Lanord, C.

    2003-04-01

    composition obtained with classical methods of a Gaindatherium molar showed a quite good correlation. These results suggest that high-resolution mesurements can be performed and that developing this method would enable a more precise description of the signal recorded in enamel.

  12. Studying heavy-ion collisions with FAUST-QTS

    NASA Astrophysics Data System (ADS)

    Cammarata, P.; Chapman, M. B.; Souliotis, G. A.; Bakhtiari, L.; Behling, S.; Bonasera, G.; Heilborn, L. A.; Mabiala, J.; McIntosh, A. B.; May, L. W.; Raphelt, A.; Youngs, M. D.; Zarrella, A.; Yennello, S. J.

    2015-04-01

    Heavy-ion collisions at lower energies provide a rich environment for investigating reaction dynamics. Recent theory has suggested a sensitivity to the symmetry energy and the equation of state via deformations of the reaction system and ternary breaking of the deformed reaction partners into three heavy fragments. A new detection system has been commissioned at Texas A&M University in an attempt to investigate some of the observables sensitive to the nuclear equation of state.

  13. <span class="hlt">Heavy-Ion</span> Imaging Applied To Medicine

    SciTech Connect

    Fabrikant, J. I.; Tobias, C. A.; Capp, M. P.; Benton, E. V.; Holley, W. R.; Gray, Joel E.; Hendee, William R.; Haus, Andrew G.; Properzio, William S.

    1980-08-18

    Heavy particle radiography is a newly developed noninvasive low dose imaging procedure with increased resolution of minute density differences in soft tissues of the body. The method utilizes accelerated high energy ions, primarily carbon and neon, at the BEVALAC accelerator at the Lawrence Berkeley Laboratory. The research program applied to medicine utilizes heavy-ion radiography for low dose mammography, for treatment planning for cancer patients, and for imaging and accurate densitometry of skeletal structures and brain and spinal neoplasms. The presentation will be illustrated with clinical cases under study. Discussion will include the potential of heavy-ion imaging, and particularly reconstruction tomography, as an adjunct to existing diagnostic imaging procedures in medicine, both for the applications to the diagnosis, management and treatment of clinical cancer in man, but also for the early detection of small soft tissue tumors at low radiation dose.

  14. Ultrarelativistic heavy ion collisions: the first billion seconds

    NASA Astrophysics Data System (ADS)

    Baym, Gordon

    2016-12-01

    I first review the early history of the ultrarelativistic heavy ion program, starting with the 1974 Bear Mountain Workshop, and the 1983 Aurora meeting of the U.S. Nuclear Science Committtee, just one billion seconds ago, which laid out the initial science goals of an ultrarelativistic collider. The primary goal, to discover the properties of nuclear matter at the highest energy densities, included finding new states of matter - the quark-gluon plasma primarily - and to use collisions to open a new window on related problems of matter in cosmology, neutron stars, supernovae, and elsewhere. To bring out how the study of heavy ions and hot, dense matter in QCD has been fulfilling these goals, I concentrate on a few topics, the phase diagram of matter in QCD, and connections of heavy ion physics to cold atoms, cosmology, and neutron stars.

  15. Sputtering Threshold Energies of Heavy Ions

    NASA Technical Reports Server (NTRS)

    Mantenieks, Maris A.

    1999-01-01

    Sputter erosion in ion thrusters has been measured in lifetests at discharge voltages as low as 25 V. Thruster operation at this discharge voltage results in component erosion rates sufficiently low to satisfy most mission requirements. It has been recognized that most of the internal sputtering in ion thrusters is done by doubly charged ions. Knowledge of the sputtering threshold voltage of a xenon molybdenum system would be beneficial in understanding the sputtering process as well as making more accurate calculations of the sputtering rates of ion thruster components. Sputtering threshold energies calculated from various formulations found in the literature results in values ranging from 28 to 200 eV. It is evident that some of these formulations cannot be relied upon to provide sputtering thresholds with any degree of accuracy. This paper re-examines the threshold energies measurements made in the early sixties by Askerov and Sena, and Stuart and Wehner. The threshold voltages as derived by Askerov and au have been reevaluated by using a different extrapolation method of sputter yields at low ion energies. The resulting threshold energies are in general similar to those measured by Stuart and Wehner. An empirical relationship is derived,for mercury and xenon ions for the ratio of the sputtering threshold energy to the sublimation energy as a function of the ratio of target to ion atomic mass.

  16. An Experimental Review on Heavy-Flavor v 2 in Heavy-Ion Collision

    DOE PAGES

    Nasim, Md.; Esha, Roli; Huang, Huan Zhong

    2016-01-01

    For overmore » a decade now, the primary purpose of relativistic heavy-ion collisions at the Relativistic Heavy-Ion Collider (RHIC) and the Large Hadron Collider (LHC) has been to study the properties of QCD matter under extreme conditions—high temperature and high density. The heavy-ion experiments at both RHIC and LHC have recorded a wealth of data in p+p, p+Pb, d+Au, Cu+Cu, Cu+Au, Au+Au, Pb+Pb, and U+U collisions at energies ranging from s N N = 7.7  GeV to 7 TeV. Heavy quarks are considered good probe to study the QCD matter created in relativistic collisions due to their very large mass and other unique properties. A precise measurement of various properties of heavy-flavor hadrons provides an insight into the fundamental properties of the hot and dense medium created in these nucleus-nucleus collisions, such as transport coefficient and thermalization and hadronization mechanisms. The main focus of this paper is to present a review on the measurements of azimuthal anisotropy of heavy-flavor hadrons and to outline the scientific opportunities in this sector due to future detector upgrade. We will mainly discuss the elliptic flow of open charmed meson ( D -meson), J / ψ , and leptons from heavy-flavor decay at RHIC and LHC energy.« less

  17. Quantum Electrodynamical Shifts in Multivalent Heavy Ions

    NASA Astrophysics Data System (ADS)

    Tupitsyn, I. I.; Kozlov, M. G.; Safronova, M. S.; Shabaev, V. M.; Dzuba, V. A.

    2016-12-01

    The quantum electrodynamics (QED) corrections are directly incorporated into the most accurate treatment of the correlation corrections for ions with complex electronic structure of interest to metrology and tests of fundamental physics. We compared the performance of four different QED potentials for various systems to access the accuracy of QED calculations and to make a prediction of highly charged ion properties urgently needed for planning future experiments. We find that all four potentials give consistent and reliable results for ions of interest. For the strongly bound electrons, the nonlocal potentials are more accurate than the local potential.

  18. Quantum Electrodynamical Shifts in Multivalent Heavy Ions.

    PubMed

    Tupitsyn, I I; Kozlov, M G; Safronova, M S; Shabaev, V M; Dzuba, V A

    2016-12-16

    The quantum electrodynamics (QED) corrections are directly incorporated into the most accurate treatment of the correlation corrections for ions with complex electronic structure of interest to metrology and tests of fundamental physics. We compared the performance of four different QED potentials for various systems to access the accuracy of QED calculations and to make a prediction of highly charged ion properties urgently needed for planning future experiments. We find that all four potentials give consistent and reliable results for ions of interest. For the strongly bound electrons, the nonlocal potentials are more accurate than the local potential.

  19. EDITORIAL: Focus on Heavy Ions in Biophysics and Medical Physics FOCUS ON HEAVY IONS IN BIOPHYSICS AND MEDICAL PHYSICS

    NASA Astrophysics Data System (ADS)

    Durante, Marco

    2008-07-01

    Interest in energetic heavy ions is rapidly increasing in the field of biomedicine. Heavy ions are normally excluded from radiation protection, because they are not normally experienced by humans on Earth. However, knowledge of heavy ion biophysics is necessary in two fields: charged particle cancer therapy (hadrontherapy), and radiation protection in space missions. The possibility to cure tumours using accelerated heavy charged particles was first tested in Berkeley in the sixties, but results were not satisfactory. However, about 15 years ago therapy with carbon ions was resumed first in Japan and then in Europe. Heavy ions are preferable to photons for both physical and biological characteristics: the Bragg peak and limited lateral diffusion ensure a conformal dose distribution, while the high relative biological effectiveness and low oxygen enhancement ration in the Bragg peak region make the beam very effective in treating radioresistant and hypoxic tumours. Recent results coming from the National Institute of Radiological Sciences in Chiba (see the paper by Dr Tsujii and co-workers in this issue) and GSI (Germany) provide strong clinical evidence that heavy ions are indeed an extremely effective weapon in the fight against cancer. However, more research is needed in the field, especially on optimization of the treatment planning and risk of late effects in normal tissue, including secondary cancers. On the other hand, high-energy heavy ions are present in galactic cosmic radiation and, although they are rare as compared to protons, they give a major contribution in terms of equivalent dose to the crews of manned space exploratory-class missions. Exploration of the Solar System is now the main goal of the space program, and the risk caused by exposure to galactic cosmic radiation is considered a serious hindrance toward this goal, because of the high uncertainty on late effects of energetic heavy nuclei, and the lack of effective countermeasures. Risks

  20. Heavy metal ions are potent inhibitors of protein folding

    SciTech Connect

    Sharma, Sandeep K.; Goloubinoff, Pierre; Christen, Philipp

    2008-07-25

    Environmental and occupational exposure to heavy metals such as cadmium, mercury and lead results in severe health hazards including prenatal and developmental defects. The deleterious effects of heavy metal ions have hitherto been attributed to their interactions with specific, particularly susceptible native proteins. Here, we report an as yet undescribed mode of heavy metal toxicity. Cd{sup 2+}, Hg{sup 2+} and Pb{sup 2+} proved to inhibit very efficiently the spontaneous refolding of chemically denatured proteins by forming high-affinity multidentate complexes with thiol and other functional groups (IC{sub 50} in the nanomolar range). With similar efficacy, the heavy metal ions inhibited the chaperone-assisted refolding of chemically denatured and heat-denatured proteins. Thus, the toxic effects of heavy metal ions may result as well from their interaction with the more readily accessible functional groups of proteins in nascent and other non-native form. The toxic scope of heavy metals seems to be substantially larger than assumed so far.

  1. Heating of heavy ions on auroral field lines

    SciTech Connect

    Nishikawa, K.I.; Okuda, H., Hasegawa, A.

    1983-01-01

    Heating of heavy ions is studied in the presence of large amplitude hydrogen cyclotron waves. A three wave decay process, in which a large amplitude pump hydrogen cyclotron wave decays into a daughter hydrogen cyclotron wave and a low frequency oxygen cyclotron wave, is studied theoretically and by numerical simulations. The numerical simulations show a decay instability resulting in strong heating of both the oxygen ions and the hydrogen ions. In particular, the high energy tail of the oxygen ions is observed in the perpendicular distribution.

  2. SAMPEX measurements of heavy ions trapped in the magnetosphere

    SciTech Connect

    Cummings, J.R.; Cummings, A.C.; Mewaldt, R.A.; Selesnick, R.S.; Stone, E.C. ); Rosenvinge, T.T. von ); Blake, J.B. )

    1993-12-01

    New observations of >15 MeV/nuc trapped heavy ions with Z [ge] 2 have been made by the S AMPEX spacecraft in low polar orbit. The composition of these ions, which are located primarily around L = 2, is dominated by He, N, O, and Ne. The N, O, and Ne ions are apparently trapped anomalous cosmic rays,'' while the origin of the trapped He flux is presently uncertain. These ions can affect the rate of single-event upsets (SEUs) in spacecraft hardware.

  3. Mutagenic effects of heavy ion radiation in plants

    NASA Astrophysics Data System (ADS)

    Mei, M.; Deng, H.; Lu, Y.; Zhuang, C.; Liu, Z.; Qiu, Q.; Qiu, Y.; Yang, T. C.

    1994-10-01

    Genetic and developmental effects of heavy ions in maize and rice were investigated. Heavy particles with various charges and energies were accelerated at the BEVALAC. The frequency of occurence of white-yellow stripes on leaves of plants developed from irradiated maize seeds increased linearly with dose, and high-LET heavy charged particles, e.g., neon, argon, and iron, were 2-12 times as effective as gamma rays in inducing this type of mutation. The effectiveness of high-LET heavy ion in (1) inhibiting rice seedling growth, (2) reducing plant fertility, (3) inducing chromosome aberration and micronuclei in root tip cells and pollen mother cells of the first generation plants developed from exposed seeds, and (4) inducing mutation in the second generation, were greater than that of low-LET gamma rays. All effects observed were dose-dependent; however, there appeared to be an optimal range of doses for inducing certain types of mutation, for example, for argon ions (400 MeV/u) at 90-100 Gy, several valuable mutant lines with favorable characters, such as semidwarf, early maturity and high yield ability, were obtained. Experimental results suggest that the potential application of heavy ions in crop improvement is promising. RFLP analysis of two semidwarf mutants induced by argon particles revealed that large DNA alterations might be involved in these mutants.

  4. Mutagenic effects of heavy ion radiation in plants

    NASA Technical Reports Server (NTRS)

    Mei, M.; Deng, H.; Lu, Y.; Zhuang, C.; Liu, Z.; Qiu, Q.; Qiu, Y.; Yang, T. C.

    1994-01-01

    Genetic and developmental effects of heavy ions in maize and rice were investigated. Heavy particles with various charges and energies were accelerated at the BEVALAC. The frequency of occurrence of white-yellow stripes on leaves of plants developed from irradiated maize seeds increased linearly with dose, and high Linear Energy Transfer (LET) heavy charged particles, e.g., neon, argon, and iron, were 2-12 times as effective as gamma rays in inducing this type of mutation. The effectiveness of high-LET heavy ion in (1) inhibiting rice seedling growth, (2) reducing plant fertility, (3) inducing chromosome aberration and micronuclei in root tip cells and pollen mother cells of the first generation plants developed from exposed seeds, and (4) inducing mutation in the second generation, were greater than that of low-LET gamma rays. All effects observed were dose-dependent; however, there appeared to be an optimal range of doses for inducing certain types of mutation, for example, for argon ions (400 MeV/u) at 90-100 Gy, several valuable mutant lines with favorable characters, such as semidwarf, early maturity and high yield ability, were obtained. Experimental results suggest that the potential application of heavy ions in crop improvement is promising. Restriction-fragment-length-polymorphism (RFLP) analysis of two semidwarf mutants induced by argon particles revealed that large DNA alterations might be involved in these mutants.

  5. Mutagenic effects of heavy ion radiation in plants

    NASA Technical Reports Server (NTRS)

    Mei, M.; Deng, H.; Lu, Y.; Zhuang, C.; Liu, Z.; Qiu, Q.; Qiu, Y.; Yang, T. C.

    1994-01-01

    Genetic and developmental effects of heavy ions in maize and rice were investigated. Heavy particles with various charges and energies were accelerated at the BEVALAC. The frequency of occurrence of white-yellow stripes on leaves of plants developed from irradiated maize seeds increased linearly with dose, and high Linear Energy Transfer (LET) heavy charged particles, e.g., neon, argon, and iron, were 2-12 times as effective as gamma rays in inducing this type of mutation. The effectiveness of high-LET heavy ion in (1) inhibiting rice seedling growth, (2) reducing plant fertility, (3) inducing chromosome aberration and micronuclei in root tip cells and pollen mother cells of the first generation plants developed from exposed seeds, and (4) inducing mutation in the second generation, were greater than that of low-LET gamma rays. All effects observed were dose-dependent; however, there appeared to be an optimal range of doses for inducing certain types of mutation, for example, for argon ions (400 MeV/u) at 90-100 Gy, several valuable mutant lines with favorable characters, such as semidwarf, early maturity and high yield ability, were obtained. Experimental results suggest that the potential application of heavy ions in crop improvement is promising. Restriction-fragment-length-polymorphism (RFLP) analysis of two semidwarf mutants induced by argon particles revealed that large DNA alterations might be involved in these mutants.

  6. Mutagenic effects of heavy ion radiation in plants.

    PubMed

    Mei, M; Deng, H; Lu, Y; Zhuang, C; Liu, Z; Qiu, Q; Qiu, Y; Yang, T C

    1994-10-01

    Genetic and developmental effects of heavy ions in maize and rice were investigated. Heavy particles with various charges and energies were accelerated at the BEVALAC. The frequency of occurrence of white-yellow stripes on leaves of plants developed from irradiated maize seeds increased linearly with dose, and high-LET heavy charged particles, e.g., neon, argon, and iron, were 2-12 times as effective as gamma rays in inducing this type of mutation. The effectiveness of high-LET heavy ion in (1) inhibiting rice seedling growth, (2) reducing plant fertility, (3) inducing chromosome aberration and micronuclei in root tip cells and pollen mother cells of the first generation plants developed from exposed seeds, and (4) inducing mutation in the second generation, were greater than that of low-LET gamma rays. All effects observed were dose-dependent; however, there appeared to be an optimal range of doses for inducing certain types of mutation, for example, for argon ions (400 MeV/u) at 90-100 Gy, several valuable mutant lines with favorable characters, such as semidwarf, early maturity and high yield ability, were obtained. Experimental results suggest that the potential application of heavy ions in crop improvement is promising. RFLP analysis of two semidwarf mutants induced by argon particles revealed that large DNA alterations might be involved in these mutants.

  7. Development of vacuum arc ion sources for heavy ion accelerator injectors and ion implantation technology (invited)

    NASA Astrophysics Data System (ADS)

    Oks, Efim M.

    1998-02-01

    The status of experimental research and ongoing development and upgrade of MEVVA-type ion sources over the last two years since the previous ICIS-95 is reviewed. There are two main application fields for this ion source: heavy ion accelerators and material surface implantation technology. For particle accelerator ion injection to accelerators it is important to enhance the fractions of multiply charged ions in the ion beam as well as controlling the charge state distribution, and to improve of beam current stability (i.e., to minimize the beam noise) and pulse-to-pulse reproducibility. For ion implantation application we need to increase both the implantation dose rate and the source lifetime (between required maintenance downtime) as well as making this kind of source more reliable and of yet low cost. Most of experimental results reported on here have been obtained in a collaborative program between research groups LBNL (Berkeley, USA), GSI (Darmstadt, Germany), HCEI (Tomsk, Russia), and other important contributions have been made by the groups at (BNU, Beijing, China), EDU (Izmir, Turkey), and elsewhere.

  8. Reducing hazardous heavy metal ions using mangium bark waste.

    PubMed

    Khabibi, Jauhar; Syafii, Wasrin; Sari, Rita Kartika

    2016-08-01

    The objective of this study was to evaluate the characteristics of mangium bark and its biosorbent ability to reduce heavy metal ions in standard solutions and wastewater and to assess changes in bark characteristics after heavy metal absorption. The experiments were conducted to determine heavy metal absorption from solutions of heavy metals alone and in mixtures as well as from wastewater. The results show that mangium bark can absorb heavy metals. Absorption percentages and capacities from single heavy metal solutions showed that Cu(2+) > Ni(2+) > Pb(2+) > Hg(2+), while those from mixture solutions showed that Hg(2+) > Cu(2+) > Pb(2+) > Ni(2+). Wastewater from gold mining only contained Cu, with an absorption percentage and capacity of 42.87 % and 0.75 mg/g, respectively. The highest absorption percentage and capacity of 92.77 % and 5.18 mg/g, respectively, were found for Hg(2+) in a mixture solution and Cu(2+) in single-metal solution. The Cu(2+) absorption process in a single-metal solution changed the biosorbent characteristics of the mangium bark, yielding a decreased crystalline fraction; changed transmittance on hydroxyl, carboxyl, and carbonyl groups; and increased the presence of Cu. In conclusion, mangium bark biosorbent can reduce hazardous heavy metal ions in both standard solutions and wastewater.

  9. Experimental Overview of Direct Photon Results in Heavy Ion Collisions

    NASA Astrophysics Data System (ADS)

    Novitzky, Norbert

    2016-07-01

    Direct photons are color blind probes and thus they provide unique opportunities to study the colored medium created in heavy ion collisions. There are many different sources of direct photons each probing different physics processes as the system evolves. In basic 2 → 2 processes the prompt photons from primary hard scatterings offer the most precise measurements of the outgoing parton energy in the opposite direction. In heavy ion collisions the created medium emits photons as thermal radiation, whose rate and anisotropies provide a unique prospective on the properties and evolution of the system. Recent results on direct photons from the LHC and RHIC experiments are briefly summarized in this paper.

  10. Development of Superconducting Focusing Quadrupoles for Heavy Ion Drivers

    SciTech Connect

    Martovetsky, N; Manahan, R; Lietzke, A F

    2001-09-10

    Heavy Ion Fusion (HIF) is exploring a promising path to a practical inertial-confinement fusion reactor. The associated heavy ion driver will require a large number of focusing quadrupole magnets. A concept for a superconducting quadrupole array, using many simple racetrack coils, was developed at LLNL. Two, single-bore quadrupole prototypes of the same design, with distinctly different conductor, were designed, built, and tested. Both prototypes reached their short sample currents with little or no training. Magnet design, and test results, are presented and discussed.

  11. Heavy ions at steamboat: summary of parallel sessions

    SciTech Connect

    Ludlam, T.W.

    1984-01-01

    The interest in heavy ions at the intersection between particle and nuclear physics is motivated by the opportunity for an entirely new approach to the understanding of fundamental interactions by studying extreme states of nuclear matter. At this conference we have seen important new results on some of the central issues including: (1) how well can we predict the landscape of the extremes - that is, the phase structure of QCD and nuclear matter; (2) can we explore it with heavy ion collisions; and (3) can we recognize the appearance of new terrain. Our present understanding of the behavior of nuclear matter under extreme conditions is briefly discussed. 16 references. (WHK)

  12. Solar wind heavy ions from flare-heated coronal plasma

    NASA Technical Reports Server (NTRS)

    Bame, S. J.; Asbridge, J. R.; Feldman, W. C.; Fenimore, E. E.; Gosling, J. T.

    1979-01-01

    Information concerning the coronal expansion is carried by solar-wind heavy ions. Distinctly different energy-per-charge ion spectra are found in two classes of solar wind having the low kinetic temperatures necessary for E/q resolution of the ion species. Heavy-ion spectra which can be resolved are most frequently observed in the low-speed interstream (IS) plasma found between high speed streams; the streams are thought to originate from coronal holes. Although the sources of the IS plasma are uncertain, the heavy-ion spectra found there contain identifiable peaks of O, Si, and Fe ions. Such spectra indicate that the IS ionization state of O is established in coronal gas at a temperature of approximately 1.6 million K, while that of Fe is frozen in farther out at about 1.5 million K. On occasion anomalous spectra are found outside IS flows in solar wind with abnormally depressed local kinetic temperatures. The anomalous spectra contain Fe(16+) ions, not usually found in IS flows, and the derived coronal freezing-in temperatures are significantly higher. The coronal sources of some of these ionizationally hot flows are identified as solar flares.

  13. Quantum Electrodynamics of Heavy Ions and Atoms

    SciTech Connect

    Shabaev, V. M.; Artemyev, A. N.; Glazov, D. A.; Tupitsyn, I. I.; Volotka, A. V.; Yerokhin, V. A.

    2006-11-07

    The present status of quantum electrodynamics (QED) theory of heavy few-electrons is reviewed. The theoretical results are compared with available experimental data. A special attention is focused on tests of QED at strong fields and on determination of the fundamental constants. A recent progress on calculations of the QED corrections to the parity nonconserving 6s-7s transition amplitude in neutral Cs is also discussed.

  14. Heavy ion acceleration at the AGS: Present and future plans

    SciTech Connect

    Lee, Y.Y.

    1989-01-01

    The Brookhaven AGS is alternating gradient synchrotron, 807 meters in circumference, which was originally designed for only protons. Using the 15 MV Brookhaven Tandem Van de Graaff as an injector, the AGS started to accelerate heavy ions of mass lighter than sulfur. Because of the relatively poor vacuum (/approximately/10/sup /minus/8/ Torr), the AGS is not able to accelerate heavier ions which could not be fully stripped of electrons at the Tandem energy. When the AGS Booster, which is under construction, is completed the operation will be extended to all species of heavy ions including gold and uranium. Because ultra-high vacuum (/approximately/10/sup /minus/11/ Torr) is planned, the Booster can accelerate partially stripped elements. The operational experience, the parameters, and scheme of heavy ion acceleration will be presented in detail from injection to extraction, as well as future injection into the new Relativistic Heavy Ion Collider (RHIC). A future plan to improve intensity of the accelerator will also be presented. 5 figs., 4 tabs.

  15. High resolution data acquisition

    DOEpatents

    Thornton, G.W.; Fuller, K.R.

    1993-04-06

    A high resolution event interval timing system measures short time intervals such as occur in high energy physics or laser ranging. Timing is provided from a clock, pulse train, and analog circuitry for generating a triangular wave synchronously with the pulse train (as seen in diagram on patent). The triangular wave has an amplitude and slope functionally related to the time elapsed during each clock pulse in the train. A converter forms a first digital value of the amplitude and slope of the triangle wave at the start of the event interval and a second digital value of the amplitude and slope of the triangle wave at the end of the event interval. A counter counts the clock pulse train during the interval to form a gross event interval time. A computer then combines the gross event interval time and the first and second digital values to output a high resolution value for the event interval.

  16. High resolution data acquisition

    DOEpatents

    Thornton, Glenn W.; Fuller, Kenneth R.

    1993-01-01

    A high resolution event interval timing system measures short time intervals such as occur in high energy physics or laser ranging. Timing is provided from a clock (38) pulse train (37) and analog circuitry (44) for generating a triangular wave (46) synchronously with the pulse train (37). The triangular wave (46) has an amplitude and slope functionally related to the time elapsed during each clock pulse in the train. A converter (18, 32) forms a first digital value of the amplitude and slope of the triangle wave at the start of the event interval and a second digital value of the amplitude and slope of the triangle wave at the end of the event interval. A counter (26) counts the clock pulse train (37) during the interval to form a gross event interval time. A computer (52) then combines the gross event interval time and the first and second digital values to output a high resolution value for the event interval.

  17. Panoramic High Resolution Spectroscopy

    NASA Astrophysics Data System (ADS)

    Freeman, K.; Bland-Hawthorn, J.

    2008-10-01

    Stellar populations in galaxies are vast repositories of fossil information. In recent years it has become possible to consider high resolution spectroscopic surveys of millions of stars. New high resolution multi-object spectrographs on 4-8m class telescopes (HERMES, WFMOS) will allow us for the first time to make large and detailed chemical abundance surveys of stars in the Galactic disk, bulge and halo, and apply the techniques of chemical tagging to recovering the fossil information left over from galaxy assembly. These instruments will have strong synergies with the GAIA astrometric satellite due to launch in 2011. The level of detail made possible by these future facilities will be necessary if we are to fully understand the physical processes involved in galaxy formation.

  18. High resolution data acquisition

    SciTech Connect

    Thornton, G.W.; Fuller, K.R.

    1992-12-31

    A high resolution event interval timing system measures short time intervals such as occur in high energy physics or laser ranging. Timing is provided from a clock pulse train and analog circuitry for generating a triangular wave synchronously with the pulse train. The triangular wave has an amplitude and slope functionally related to the time elapsed during each clock pulse in the train. A converter forms a first digital value of the amplitude and slope of the triangle wave at the start of the event interval and a second digital value of the amplitude and slope of the triangle wave at the end of the event interval. A counter counts the clock pulse train during the interval to form a gross event interval time. A computer then combines the gross event interval time and the first and second digital values to output a high resolution value for the event interval.

  19. [Heavy charged particles radiotherapy--mainly carbon ion beams].

    PubMed

    Yanagi, Takeshi; Tsuji, Hiroshi; Tsujii, Hirohiko

    2003-12-01

    Carbon ion beams have superior dose distribution allowing selective irradiation to the tumor while minimizing irradiation to the surrounding normal tissues. Furthermore, carbon ions produce an increased density of local energy deposition with high-energy transfer (LET) components, resulting in radiobiological advantages. Stimulated by the favorable results in fast neutrons, helium ions, and neon ions, a clinical trial of carbon ion therapy was begun at the National Institute of Radiological Sciences in 1994. Carbon ions were generated by a medically dedicated accelerator (HIMAC, Heavy Ion Medical Accelerator in Chiba, Japan), which was the world's first heavy ion accelerator complex dedicated to medical use in a hospital environment. In general, patients were selected for treatment when their tumors could not be expected to respond favorably to conventional forms of therapy. A total of 1601 patients were registered in this clinical trial so far. The normal tissue reactions were acceptable, and there were no carbon related deaths. Carbon ion radiotherapy seemed to be a clinically feasible curative treatment modality, and appears to offer improved results not only over conventional X-rays but also even over surgery in some selected carcinomas.

  20. High-Resolution Autoradiography

    NASA Technical Reports Server (NTRS)

    Towe, George C; Gomberg, Henry J; Freemen, J W

    1955-01-01

    This investigation was made to adapt wet-process autoradiography to metallurgical samples to obtain high resolution of segregated radioactive elements in microstructures. Results are confined to development of the technique, which was perfected to a resolution of less than 10 microns. The radioactive samples included carbon-14 carburized iron and steel, nickel-63 electroplated samples, a powder product containing nickel-63, and tungsten-185 in N-155 alloy.

  1. Ultra high resolution tomography

    SciTech Connect

    Haddad, W.S.

    1994-11-15

    Recent work and results on ultra high resolution three dimensional imaging with soft x-rays will be presented. This work is aimed at determining microscopic three dimensional structure of biological and material specimens. Three dimensional reconstructed images of a microscopic test object will be presented; the reconstruction has a resolution on the order of 1000 A in all three dimensions. Preliminary work with biological samples will also be shown, and the experimental and numerical methods used will be discussed.

  2. Laser-driven multicharged heavy ion beam acceleration

    NASA Astrophysics Data System (ADS)

    Nishiuchi, M.; Sakaki, H.; Esirkepov, T. Z.; Nishio, K.; Pikuz, T. A.; Faenov, A. Y.; Pirozhkov, A. S.; Sagisaka, A.; Ogura, K.; Kanasaki, M.; Kiriyama, H.; Fukuda, Y.; Kando, M.; Yamauchi, T.; Watanabe, Y.; Bulanov, S. V.; Kondo, K.; Imai, K.; Nagamiya, S.

    2015-05-01

    Experimental demonstration of multi-charged heavy ion acceleration from the interaction between the ultra-intense short pulse laser system and the metal target is presented. The laser pulse of <10 J laser energy, 36 fs pulse width, and the contrast level of ~1010 from 200 TW class Ti:sapphire J-KAREN laser system at JAEA is used in the experiment. Almost fully stripped Fe ions accelerated up to 0.9 GeV are demonstrated. This is achieved by the high intensity laser field of ˜ 1021Wcm-2 interacting with the solid density target. The demonstrated iron ions with high charge to mass ratio (Q/M) is difficult to be achieved by the conventional heavy ion source technique in the accelerators.

  3. Realistic modeling of chamber transport for heavy-ion fusion

    SciTech Connect

    Sharp, W.M.; Grote, D.P.; Callahan, D.A.; Tabak, M.; Henestroza, E.; Yu, S.S.; Peterson, P.F.; Welch, D.R.; Rose, D.V.

    2003-05-01

    Transport of intense heavy-ion beams to an inertial-fusion target after final focus is simulated here using a realistic computer model. It is found that passing the beam through a rarefied plasma layer before it enters the fusion chamber can largely neutralize the beam space charge and lead to a usable focal spot for a range of ion species and input conditions.

  4. Plasma Lipidome Analysis by Liquid Chromatography-High Resolution Mass Spectrometry and Ion Mobility of Hypertriglyceridemic Patients on Extended-Release Nicotinic Acid: a Pilot Study.

    PubMed

    Ferchaud-Roucher, Véronique; Croyal, Mikaël; Moyon, Thomas; Zair, Yassine; Krempf, Michel; Ouguerram, Khadija

    2017-07-28

    Plasma high triacylglycerols and low HDL-C concentration are associated with increased cardiovascular events. Extended-release nicotinic acid (ERN) was shown to reduce plasma triacylglycerols and total cholesterol but also to markedly increase high-density lipoprotein-cholesterol (HDL-C). No data on the effect of ERN on different species of triacylglycerol, cholesteryl ester, and phospholipids are available. In this study, we applied a nontargeted lipidomic approach to investigate the plasma and lipoproteins lipids profile of hypertriglyceridemic patients treated with ERN or a placebo in order to identify new lipids markers associated with this treatment. Eight hypertriglyceridemic patients enrolled in a crossover randomized trial with ERN for 8 weeks and treated with 2 g/day of ERN or a placebo. Ultra-performance liquid chromatography (UPLC) coupled to high-resolution mass spectrometry (HRMS) was used in mass spectrometry energy mode (HRMS(E)) combined with ion mobility spectrometry to characterize the plasma and very low density lipoprotein (VLDL), low density lipoprotein (LDL) and high density lipoprotein (HDL) lipidome. The accuracy and precision of the method were validated on plasma samples. Compared to placebo, among 155 plasma lipids characterized using UPLC-ESI-HRMS, a multivariate analysis revealed a significant increase of lysophosphatidylcholine (LPC 20:5), a significant decrease of phosphatidylethanolamine (PE 16:0/22:3) and sphingomyelin (SM d18:1/22:0) and a decrease of triacylglycerol (TG 16:0/16:1/18:2) after ERN treatment. Analysis of these lipids in lipoproteins showed an increase of LPC (20:5) in HDL, a decrease of PE (16:0/22:3) in HDL and LDL, of SM (d18:1/22:0) in VLDL and LDL and of TG (16:0/16:1/18:2) in VLDL. This lipidomic strategy characterized new specific lipid markers likely to be involved in the effect of ERN on cardiovascular risk opening a new strategy to analyze randomized controlled with this treatment. NCT01216956.

  5. NUMEN Project @ LNS : Heavy ions double charge exchange reactions towards the 0νββ nuclear matrix element determination

    SciTech Connect

    Agodi, C. Calabretta, L.; Calanna, A.; Carbone, D.; Cavallaro, M.; Colonna, M.; Cuttone, G.; Finocchiaro, P.; Pandola, L.; Rifuggiato, D.; Tudisco, S.; Cappuzzello, F.; Greco, V.; Bonanno, D. L.; Bongiovanni, D. G.; Longhitano, F.; Branchina, V.; Foti, A.; Lo Presti, D.; Lanzalone, G.; and others

    2015-10-28

    In the NUMEN Project it is proposed an innovative technique to access the nuclear matrix elements entering in the expression of the life-time of the neutrinoless double beta decay, using relevant cross sections of double charge exchange reactions. A key aspect is the use of MAGNEX large acceptance magnetic spectrometer, for the detection of the ejectiles, and of the INFN Laboratori Nazionali del Sud (LNS) K800 Superconducting Cyclotron (CS), for the acceleration of the required high resolution and low emittance heavy-ion beams.

  6. Simultaneous Qualitative Assessment and Quantitative Analysis of Metabolites (Phenolics, Nucleosides and Amino Acids) from the Roots of Fresh Gastrodia elata Using UPLC-ESI-Triple Quadrupole Ion MS and ESI- Linear Ion Trap High-Resolution MS

    PubMed Central

    Chen, Sha; Liu, Jun Qiu; Xiao, Hui; Zhang, Jun; Liu, An

    2016-01-01

    A sensitive, effective and optimized method, based on ultra performance liquid chromatography (UPLC) coupled with ESI-triple quadrupole ion MS and ESI-linear ion trap high-resolution MS, has been developed for the simultaneous quantitative and qualitative determination of phenolics, nucleosides and amino acids in the roots of fresh Gastrodia elata. Optimization of the analytical method provided higher separation efficiency and better peak resolution for the targeted compounds. The simultaneous separation protocols were also optimized by routinely using accurate mass measurements, within 5 ppm error, for each molecular ion and the subsequent fragment ions. In total, 31 compounds, including 23 phenolics, two nucleosides, four amino acids, one gastrodin and one other compound were identified or tentatively characterized. Mono-substituted parishin glucoside (9), methoxy mono-substituted parishin (13), methyl parishin (26), p-hydroxybenzyl di-substituted parishin (29), and p-hydroxybenzyl parishin (31) were tentatively identified as new compounds. Principal metabolite content analysis and the composition of eight representative G. elata cultivars of various species indicated that geographic insulation was the main contributor to clustering. PMID:26954012

  7. Preliminary result of rapid solenoid for controlling heavy-ion beam parameters of laser ion source

    DOE PAGES

    Okamura, M.; Sekine, M.; Ikeda, S.; ...

    2015-03-13

    To realize a heavy ion inertial fusion driver, we have studied a possibility of laser ion source (LIS). A LIS can provide high current high brightness heavy ion beams, however it was difficult to manipulate the beam parameters. To overcome the issue, we employed a pulsed solenoid in the plasma drift section and investigated the effect of the solenoid field on singly charged iron beams. The rapid ramping magnetic field could enhance limited time slice of the current and simultaneously the beam emittance changed accordingly. This approach may also useful to realize an ion source for HIF power plant.

  8. Progress report on the Heavy Ions in Space (HIIS) experiment

    NASA Technical Reports Server (NTRS)

    Adams, James H., Jr.; Beahm, Lorraine P.; Boberg, Paul R.; Tylka, Allan J.

    1993-01-01

    One of the objectives of the Heavy Ions In Space (HIIS) experiment is to investigate heavy ions which appear at Long Duration Exposure Facility (LDEF) below the geomagnetic cutoff for fully-ionized galactic cosmic rays. Possible sources of such 'below-cutoff' particles are partially-ionized solar energetic particles, the anomalous component of cosmic rays, and magnetospherically-trapped particles. In recent years, there have also been reports of below-cutoff ions which do not appear to be from any known source. Although most of these observations are based on only a handful of ions, they have led to speculation about 'partially-ionized galactic cosmic rays' and 'near-by cosmic ray sources'. The collecting power of HIIS is order of magnitude larger than that of the instruments which reported these results, so HIIS should be able to confirm these observations and perhaps discover the source of these particles. Preliminary results on below-cutoff heavy-ions are reported. Observations to possible known sources of such ions are compared. A second objective of the HIIS experiment is to measure the elemental composition of ultraheavy galactic cosmic rays, beginning in the tin-barium region of the periodic table. A report on the status of this analysis is presented.

  9. Smart responsive microcapsules capable of recognizing heavy metal ions.

    PubMed

    Pi, Shuo-Wei; Ju, Xiao-Jie; Wu, Han-Guang; Xie, Rui; Chu, Liang-Yin

    2010-09-15

    Smart responsive microcapsules capable of recognizing heavy metal ions are successfully prepared with oil-in-water-in-oil double emulsions as templates for polymerization in this study. The microcapsules are featured with thin poly(N-isopropylacrylamide-co-benzo-18-crown-6-acrylamide) (P(NIPAM-co-BCAm)) membranes, and they can selectively recognize special heavy metal ions such as barium(II) or lead(II) ions very well due to the "host-guest" complexation between the BCAm receptors and barium(II) or lead(II) ions. The stable BCAm/Ba(2+) or BCAm/Pb(2+) complexes in the P(NIPAM-co-BCAm) membrane cause a positive shift of the volume phase transition temperature of the crosslinked P(NIPAM-co-BCAm) hydrogel to a higher temperature, and the repulsion among the charged BCAm/Ba(2+) or BCAm/Pb(2+) complexes and the osmotic pressure within the P(NIPAM-co-BCAm) membranes result in the swelling of microcapsules. Induced by recognizing barium(II) or lead(II) ions, the prepared microcapsules with P(NIPAM-co-BCAm) membranes exhibit isothermal and significant swelling not only in outer and inner diameters but also in the membrane thickness. The proposed microcapsules in this study are highly attractive for developing smart sensors and/or carriers for detection and/or elimination of heavy metal ions.

  10. Inferring magnetospheric heavy ion density using EMIC waves

    NASA Astrophysics Data System (ADS)

    Kim, Eun-Hwa; Johnson, Jay R.; Kim, Hyomin; Lee, Dong-Hun

    2015-08-01

    We present a method to infer heavy ion concentration ratios from electromagnetic ion cyclotron (EMIC) wave observations that result from ion-ion hybrid (IIH) resonance. A key feature of the IIH resonance is the concentration of wave energy in a field-aligned resonant mode that exhibits linear polarization. These mode-converted waves at the IIH resonance are localized at the location where the frequency of a compressional wave driver matches the IIH resonance condition, which depends sensitively on the heavy ion concentration. This dependence makes it possible to estimate the heavy ion concentration ratio. In this paper, we evaluate the absorption coefficients at the IIH resonance at Earth's geosynchronous orbit for variable concentrations of He+ and wave frequencies using a dipole magnetic field model. We find that the resonance only occurs over a limited range of wave frequency such that the IIH resonance frequency is close to but not exactly the same as the crossover frequency. Using the wave absorption and EMIC waves observed from the GOES 12 satellite, we demonstrate how this technique can be used to estimate the He+ concentration of around 4% near L = 6.6 assuming electron-H+-He+ plasma.

  11. Heavy ion induced changes in small intestinal parameters

    NASA Astrophysics Data System (ADS)

    Carr, K. E.; McCullough, J. S.; Brennan, P.; Hayes, T. L.; Ainsworth, E. J.; Nelson, A. C.

    1994-10-01

    The effects on 17 different structural parameters of mouse small intestine three days after treatment with three types of heavy ion (neon, iron and niobium) are compared, the first two being of particular relevance to space flight. The data for niobium are given in full, showing that changes after niobium ion treatment are not standard and are concentrated in the epithelial compartment, with few of the parameters having a response which is dose dependent. When comparisons are made for the three types of heavy ion, the damage is greatest after neon ion irradiation, implying that the additional non-epithelial damage produced as LET rises from X rays through neutrons to neon ions is not necessarily maintained as LET continues to rise. Further understanding is therefore needed of the balance between changes affecting the vascular and absorptive components of the organ. Variation from group to group is also important, as is variation of strain or gastrointestinal status. All such factors are important in the understanding of changes in multicellular organs after exposure to heavy ion radiation.

  12. Heavy Ion Carcinogenesis and Human Space Exploration

    NASA Technical Reports Server (NTRS)

    Cucinotta, Francis A.; Durante, Marco

    2008-01-01

    Prior to the human exploration of Mars or long duration stays on the Earth s moon, the risk of cancer and other diseases from space radiation must be accurately estimated and mitigated. Space radiation, comprised of energetic protons and heavy nuclei, has been show to produce distinct biological damage compared to radiation on Earth, leading to large uncertainties in the projection of cancer and other health risks, while obscuring evaluation of the effectiveness of possible countermeasures. Here, we describe how research in cancer radiobiology can support human missions to Mars and other planets.

  13. Heavy ion carcinogenesis and human space exploration.

    PubMed

    Durante, Marco; Cucinotta, Francis A

    2008-06-01

    Before the human exploration of Mars or long-duration missions on the Earth's moon, the risk of cancer and other diseases from space radiation must be accurately estimated and mitigated. Space radiation, comprised of energetic protons and heavy nuclei, has been shown to produce distinct biological damage compared with radiation on Earth, leading to large uncertainties in the projection of cancer and other health risks, and obscuring evaluation of the effectiveness of possible countermeasures. Here, we describe how research in cancer radiobiology can support human missions to Mars and other planets.

  14. Modeling Electron-Cloud Effects in Heavy-Ion Accelerators

    SciTech Connect

    Cohen, R H; Friedman, A; Lund, S M; Molvik, A W; Lee, E P; Azevedo, T; Vay, J; Stoltz, P; Veitzer, S

    2004-09-21

    Stray electrons can arise in positive-ion accelerators for heavy ion fusion or other applications as a result of ionization of ambient gas or gas released from walls due to halo-ion impact, or as a result of secondary- electron emission. We summarize results from several studies undertaken in conjunction with an effort to develop a self-consistent modeling capability: (1) Calculation of the electron cloud produced by electron desorption from computed beam-ion loss, which illustrates the importance of retaining ion reflection at the walls; (2) Simulation of the effect of specified electron cloud distributions on ion beam dynamics; and (3) analysis of an instability associated with a resonance between the beam-envelope ''breathing'' mode and the electron perturbation. We also report first results from a long-timestep algorithm for electron dynamics, which holds promise for efficient simultaneous solution of electron and ion dynamics. One conclusion from study (2) is that heavy-ion beams are surprisingly robust to electron clouds, compared to a priori expectations.

  15. Trends in Device SEE Susceptibility from Heavy Ions

    NASA Technical Reports Server (NTRS)

    Nichols, D. K.; Coss, J. R.; McCarty, K. P.; Schwartz, H. R.; Swift, G. M.; Watson, R. K.; Koga, R.; Crain, W. R.; Crawford, K. B.; Hansel, S. J.

    1995-01-01

    The sixth set of heavy ion single event effects (SEE) test data have been collected since the last IEEE publications in December issues of IEEE - Nuclear Science Transactions for 1985, 1987, 1989, 1991, and the IEEE Workshop Record, 1993. Trends in SEE susceptibility (including soft errors and latchup) for state-of- are evaluated.

  16. Three-dimensional Model of Tissue and Heavy Ions Effects

    NASA Technical Reports Server (NTRS)

    Ponomarev, Artem L.; Sundaresan, Alamelu; Huff, Janice L.; Cucinotta, Francis A.

    2007-01-01

    A three-dimensional tissue model was incorporated into a new Monte Carlo algorithm that simulates passage of heavy ions in a tissue box . The tissue box was given as a realistic model of tissue based on confocal microscopy images. The action of heavy ions on the cellular matrix for 2- or 3-dimensional cases was simulated. Cells were modeled as a cell culture monolayer in one example, where the data were taken directly from microscopy (2-d cell matrix), and as a multi-layer obtained from confocal microscopy (3-d case). Image segmentation was used to identify cells with precise areas/volumes in an irradiated cell culture monolayer, and slices of tissue with many cell layers. The cells were then inserted into the model box of the simulated physical space pixel by pixel. In the case of modeled tissues (3-d), the tissue box had periodic boundary conditions imposed, which extrapolates the technique to macroscopic volumes of tissue. For the real tissue (3-d), specific spatial patterns for cell apoptosis and necrosis are expected. The cell patterns were modeled based on action cross sections for apoptosis and necrosis estimated from current experimental data. A spatial correlation function indicating a higher spatial concentration of damaged cells from heavy ions relative to the low-LET radiation cell damage pattern is presented. The spatial correlation effects among necrotic cells can help studying microlesions in organs, and probable effects of directionality of heavy ion radiation on epithelium and endothelium.

  17. Heavy ion collisions and the pre-equilibrium exciton model

    SciTech Connect

    Betak, E.

    2012-10-20

    We present a feasible way to apply the pre-equilibrium exciton model in its masterequation formulation to heavy-ion induced reactions including spin variables. Emission of nucleons, {gamma}'s and also light clusters is included in our model.

  18. Elastic recoil detection (ERD) with extremely heavy ions

    NASA Astrophysics Data System (ADS)

    Forster, J. S.; Currie, P. J.; Davies, J. A.; Siegele, R.; Wallace, S. G.; Zelenitsky, D.

    1996-06-01

    Extremely heavy-ion beams such as 209Bi in elastic recoil detection (ERD) make ERD a uniquely valuable technique for thin-film analysis of elements with mass ≤ 100. We report ERD measurements of compositional analysis of dinosaur eggshells and bones. We also show the capability of the ERD technique on studies of thin-film, high-temperature superconductors.

  19. Three-dimensional Model of Tissue and Heavy Ions Effects

    NASA Technical Reports Server (NTRS)

    Ponomarev, Artem L.; Sundaresan, Alamelu; Huff, Janice L.; Cucinotta, Francis A.

    2007-01-01

    A three-dimensional tissue model was incorporated into a new Monte Carlo algorithm that simulates passage of heavy ions in a tissue box . The tissue box was given as a realistic model of tissue based on confocal microscopy images. The action of heavy ions on the cellular matrix for 2- or 3-dimensional cases was simulated. Cells were modeled as a cell culture monolayer in one example, where the data were taken directly from microscopy (2-d cell matrix), and as a multi-layer obtained from confocal microscopy (3-d case). Image segmentation was used to identify cells with precise areas/volumes in an irradiated cell culture monolayer, and slices of tissue with many cell layers. The cells were then inserted into the model box of the simulated physical space pixel by pixel. In the case of modeled tissues (3-d), the tissue box had periodic boundary conditions imposed, which extrapolates the technique to macroscopic volumes of tissue. For the real tissue (3-d), specific spatial patterns for cell apoptosis and necrosis are expected. The cell patterns were modeled based on action cross sections for apoptosis and necrosis estimated from current experimental data. A spatial correlation function indicating a higher spatial concentration of damaged cells from heavy ions relative to the low-LET radiation cell damage pattern is presented. The spatial correlation effects among necrotic cells can help studying microlesions in organs, and probable effects of directionality of heavy ion radiation on epithelium and endothelium.

  20. Overview of US heavy-ion fusion progress and plans

    SciTech Connect

    Logan, B.G.

    2004-06-01

    Significant experimental and theoretical progress has been made in the U.S. heavy ion fusion program on high-current sources, transport, final focusing, chambers and targets for inertial fusion energy (IFE) driven by induction linac accelerators seek to provide the scientific and technical basis for the Integrated Beam Experiment (IBX), an integrated source-to-target physics experiment recently included in the list of future facilities planned by the U.S. Department of Energy. To optimize the design of IBX and future inertial fusion energy drivers, current HIF-VNL research is addressing several key issues (representative, not inclusive): gas and electron cloud effects which can exacerbate beam loss at high beam perveance and magnet aperture fill factors; ballistic neutralized and assisted-pinch focusing of neutralized heavy ion beams; limits on longitudinal compression of both neutralized and un-neutralized heavy ion bunches; and tailoring heavy ion beams for uniform target energy deposition for high energy density physics (HEDP) studies.

  1. Operational Stochastic Cooling in the Relativistic Heavy-Ion Collider

    SciTech Connect

    Blaskiewicz, M.; Brennan, J. M.; Severino, F.

    2008-05-02

    Operational stochastic cooling of 100 GeV/nucleon gold beams has been achieved in the BNL Relativistic Heavy-Ion Collider. We discuss the physics and technology of the longitudinal cooling system and present results with the beams. A simulation algorithm is described and shown to accurately model the system.

  2. Connecting QGP-Heavy Ion Physics to the Early Universe

    NASA Astrophysics Data System (ADS)

    Rafelski, Johann

    2013-10-01

    We discuss properties and evolution of quark-gluon plasma in the early Universe and compare to laboratory heavy ion experiments. We describe how matter and antimatter emerged from a primordial soup of quarks and gluons. We focus our discussion on similarities and differences between the early Universe and the laboratory experiments.

  3. Electromagnetic dissociation effects in galactic heavy-ion fragmentation

    NASA Technical Reports Server (NTRS)

    Norbury, J. W.; Townsend, L. W.

    1986-01-01

    Methods for calculating cross sections for the breakup of galactic heavy ions by the Coulomb fields of the interacting nuclei are presented. By using the Weizsacker-Williams method of virtual quanta, estimates of electromagnetic dissociation cross sections for a variety of reactions applicable to galactic cosmic ray shielding studies are presented and compared with other predictions and with available experimental data.

  4. Probing the nuclear structure with heavy-ion reactions

    SciTech Connect

    Broglia, R.A.

    1982-01-01

    Nuclei display distortions in both ordinary space and in gauge space. It is suggested that it is possible to learn about the spatial distribution of the Nilsson orbitals and about the change of the pairing gap with the rotational frequency through the analysis of one- and two-nucleon transfer reactions induced in heavy-ion collisions.

  5. Photon and dilepton production in high energy heavy ion collisions

    DOE PAGES

    Sakaguchi, Takao

    2015-05-07

    The recent results on direct photons and dileptons in high energy heavy ion collisions, obtained particularly at RHIC and LHC are reviewed. The results are new not only in terms of the probes, but also in terms of the precision. We shall discuss the physics learned from the results.

  6. Photon and dilepton production in high energy heavy ion collisions

    SciTech Connect

    Sakaguchi, Takao

    2015-05-07

    The recent results on direct photons and dileptons in high energy heavy ion collisions, obtained particularly at RHIC and LHC are reviewed. The results are new not only in terms of the probes, but also in terms of the precision. We shall discuss the physics learned from the results.

  7. Heavy-ion reaction mechanisms studied with the spin spectrometer

    SciTech Connect

    Halbert, M.L.

    1983-01-01

    Experimental data and statistical-model calculations for xn and ..cap alpha..xn products of the reaction /sup 20/Ne + /sup 146/Nd at 136 MeV are shown to be in generally good agreement, indicating that equilibrium processes are dominant. Preliminary results on the heavy-ion ejectiles from /sup 19/F + /sup 159/Tb are presented.

  8. Overview of Device SEE Susceptibility from Heavy Ions

    NASA Technical Reports Server (NTRS)

    Nichols, D. K.; Coss, J. R.; McCarthy, K. P.; Schwartz, H. R.; Smith, L. S.

    1998-01-01

    A fifth set of heavy ion single event effects (SEE) test data have been collected since the last IEEE publications (1,2,3,4) in December issues for 1985, 1987, 1989, and 1991. Trends in SEE susceptibility (including soft errors and latchup) for state-of-the-art parts are evaluated.

  9. Gauge/String Duality, Hot QCD and Heavy Ion Collisions

    NASA Astrophysics Data System (ADS)

    Casalderrey-Solana, Jorge; Liu, Hong; Mateos, David; Rajagopal, Krishna; Wiedemann, Urs Achim

    2014-06-01

    1. Opening remarks; 2. A heavy ion phenomenology primer; 3. Results from lattice QCD at nonzero temperature; 4. Introducing the gauge/string duality; 5. A duality toolbox; 6. Bulk properties of strongly coupled plasma; 7. From hydrodynamics for far-from-equilibrium dynamics; 8. Probing strongly coupled plasma; 9. Quarkonium mesons in strongly coupled plasma; 10. Concluding remarks and outlook; Appendixes; References; Index.

  10. The chromatic correction in RHIC (Relativistic Heavy Ion Collider)

    SciTech Connect

    Lee, S.Y.; Dell, G.F.; Hahn, H.; Parzen, G.

    1987-01-01

    The scheme for the correction of chromatic effects in the Relativistic Heavy Ion Collider at BNL is discussed. This scheme uses six families of sextupoles excited by four independent power supplies, and provides adequate control of linear and quadratic terms in the tune vs momentum dependence and reduces the variation of the betatron amplitude, vs momentum.

  11. Creating The Perfect Liquid In Heavy-Ion Collisions

    SciTech Connect

    Jacak, B.; Steinberg, P.

    2010-05-01

    In 2005 the four experimental groups at Brookhaven National Laboratory's Relativistic Heavy Ion Collider (RHIC) announced that collisions of gold nuclei at ultrarelativistic energies produced a 'perfect liquid' of quarks and gluons. That's something quite different from the gaseous quark-gluon state theorists and experimenters were expecting from quantum chromodynamics, the standard theory of the strong interaction.

  12. Pressure Isotropization in High Energy Heavy Ion Collisions

    NASA Astrophysics Data System (ADS)

    Epelbaum, Thomas; Gelis, François

    2013-12-01

    The early stages of high energy heavy ion collisions are studied in the color glass condensate framework, with a real-time classical lattice simulation. When increasing the coupling constant, we observe a rapid increase of the ratio of longitudinal to transverse pressure. The transient regime that precedes this behavior is of the order of 1fm/c.

  13. Formation of Antideuterons in Heavy-Ion Collisions

    SciTech Connect

    Ioffe, B.L.; Shushpanov, I.A.; Zyablyuk, K.N.

    2005-02-01

    The antideuteron production rate at high-energy heavy-ion collisions is calculated based on the concept of d-bar formation by antinucleons which move in the mean field of the fireball constituents (mainly pions). The explicit formula is presented for the coalescence parameter B{sub 2} in terms of deuteron binding energy and fireball volume.

  14. On final conditions in high energy heavy ion Collisions

    SciTech Connect

    Sinyukov, Yu.M.; Akkelin, S.V.; Xu, N.

    1998-06-01

    Motivated by the recent experimental observations, wediscuss the freeze-out properties of the fireball created in centralheavy ion collisions. We find that the freeze-out conditions, liketemperature, velocity gradient near center of the fireball, are similarfor different colliding systems and beam energies. This means that thetransverse flow is stronger in the collisions of heavy nuclei than thatof the light ones.

  15. Heavy negative ions in Titan's ionosphere: Altitude and latitude dependence

    NASA Astrophysics Data System (ADS)

    Coates, A. J.; Wellbrock, A.; Lewis, G. R.; Jones, G. H.; Young, D. T.; Crary, F. J.; Waite, J. H.

    2009-12-01

    One of the unexpected results of the Cassini mission was the discovery of negative ions at altitudes between 950 and 1400 km in Titan's ionosphere with masses up to 10,000 amu/q [Coates, A.J., Crary, F.J., Lewis, G.R., Young, D.T., Waite Jr., J.H., Sittler Jr., E.C., 2007. Discovery of heavy negative ions in Titan's ionosphere. Geophys. Res. Lett., 34, L22103, doi:10.1029/2007GL030978; Waite Jr., J.H., Young, D. T., Coates, A. J., Crary, F. J., Magee, B. A., Mandt, K. E., Westlake, J. H., 2008. The Source of Heavy Organics and Aerosols in Titan's Atmosphere, submitted to Organic Matter in Space, Proceedings IAU Symposium no. 251]. These ions are detected at low altitudes during Cassini's closest Titan encounters by the Cassini plasma spectrometer (CAPS) electron spectrometer. This result is important as it is indicative of complex hydrocarbon and nitrile chemical processes at work in Titan's high atmosphere. They may play a role in haze formation and ultimately in the formation of heavy particles (tholins), which fall through Titan's atmosphere and build up on the surface. During Cassini's prime mission negative ions were observed on 23 Titan encounters, including 7 in addition to those reported by Coates et al. [Coates, A.J., Crary, F.J., Lewis, G.R., Young, D.T., Waite Jr., J.H., Sittler Jr., E.C., 2007. Discovery of heavy negative ions in Titan's ionosphere. Geophys. Res. Lett., 34, L22103, doi:10.1029/2007GL030978]. Here, we also examine the altitude and latitude dependence of the high-mass negative ions observed in Titan's ionosphere, and we examine the implications of these results. We find that the maximum negative ion mass is higher at low altitude and at high latitudes. We also find a weaker dependence of the maximum mass on solar zenith angle.

  16. Fourth workshop on experiments and detectors for a relativistic heavy ion collider

    SciTech Connect

    Fatyga, M.; Moskowitz, B.

    1990-01-01

    This report contains papers on the following topics: physics at RHIC; flavor flow from quark-gluon plasma; space-time quark-gluon cascade; jets in relativistic heavy ion collisions; parton distributions in hard nuclear collisions; experimental working groups, two-arm electron/photon spectrometer collaboration; total and elastic pp cross sections; a 4{pi} tracking TPC magnetic spectrometer; hadron spectroscopy; efficiency and background simulations for J/{psi} detection in the RHIC dimuon experiment; the collision regions beam crossing geometries; Monte Carlo simulations of interactions and detectors; proton-nucleus interactions; the physics of strong electromagnetic fields in collisions of relativistic heavy ions; a real time expert system for experimental high energy/nuclear physics; the development of silicon multiplicity detectors; a pad readout detector for CRID/tracking; RHIC TPC R D progress and goals; development of analog memories for RHIC detector front-end electronic systems; calorimeter/absorber optimization for a RHIC dimuon experiment; construction of a highly segmented high resolution TOF system; progress report on a fast, particle-identifying trigger based on ring-imaging and highly integrated electronics for a TPC detector.

  17. Review of highly charged heavy ion production with electron cyclotron resonance ion source (invited)

    NASA Astrophysics Data System (ADS)

    Nakagawa, T.

    2014-02-01

    The electron cyclotron resonance ion source (ECRIS) plays an important role in the advancement of heavy ion accelerators and other ion beam applications worldwide, thanks to its remarkable ability to produce a great variety of intense highly charged heavy ion beams. Great efforts over the past decade have led to significant ECRIS performance improvements in both the beam intensity and quality. A number of high-performance ECRISs have been built and are in daily operation or are under construction to meet the continuously increasing demand. In addition, comprehension of the detailed and complex physical processes in high-charge-state ECR plasmas has been enhanced experimentally and theoretically. This review covers and discusses the key components, leading-edge developments, and enhanced ECRIS performance in the production of highly charged heavy ion beams.

  18. Means for obtaining a metal ion beam from a heavy-ion cyclotron source

    DOEpatents

    Hudson, E.D.; Mallory, M.L.

    1975-08-01

    A description is given of a modification to a cyclotron ion source used in producing a high intensity metal ion beam. A small amount of an inert support gas maintains the usual plasma arc, except that it is necessary for the support gas to have a heavy mass, e.g., xenon or krypton as opposed to neon. A plate, fabricated from the metal (or anything that can be sputtered) to be ionized, is mounted on the back wall of the ion source arc chamber and is bombarded by returning energetic low-charged gas ions that fail to cross the initial accelerating gap between the ion source and the accelerating electrode. Some of the atoms that are dislodged from the plate by the returning gas ions become ionized and are extracted as a useful beam of heavy ions. (auth)

  19. Saturn's rings - high resolution

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Voyager 2 obtained this high-resolution picture of Saturn's rings Aug. 22, when the spacecraft was 4 million kilometers (2.5 million miles) away. Evident here are the numerous 'spoke' features, in the B-ring; their very sharp, narrow appearance suggests short formation times. Scientists think electromagnetic forces are responsible in some way for these features, but no detailed theory has been worked out. Pictures such as this and analyses of Voyager 2's spoke movies may reveal more clues about the origins of these complex structures. The Voyager project is managed for NASA by the Jet Propulsion Laboratory, Pasadena, Calif.

  20. Heavy-ion radiation induced bystander effect in mice

    NASA Astrophysics Data System (ADS)

    Liang, Shujian; Sun, Yeqing; Zhang, Meng; Wang, Wei; Cui, Changna

    2012-07-01

    Radiation-induced bystander effect is defined as the induction of damage in neighboring non-hit cells by signals released from directly-irradiated cells. Recently, Low dose of high LET radiation induced bystander effects in vivo have been reported more and more. It has been indicated that radiation induced bystander effect was localized not only in bystander tissues but also in distant organs. Genomic, epigenetic, metabolomics and proteomics play significant roles in regulating heavy-ion radiation stress responses in mice. To identify the molecular mechanism that underlies bystander effects of heavy-ion radiation, the male mice head were exposed to 2000mGy dose of 12C heavy-ion radiation and the distant organ liver was detected on 1h, 6h, 12h and 24h after radiation, respectively. MSAP was used to monitor the level of polymorphic DNA methylation changes. The results show that heavy-ion irradiate mouse head can induce liver DNA methylation changes significantly. The percent of DNA methylation changes are time-dependent and highest at 6h after radiation. We also prove that the hypo-methylation changes on 1h and 6h after irradiation. But the expression level of DNA methyltransferase DNMT3a is not changed. UPLC/Synapt HDMS G2 was employed to detect the proteomics of bystander liver 1h after irradiation. 64 proteins are found significantly different between treatment and control group. GO process show that six of 64 which were unique in irradiation group are associated with apoptosis and DNA damage response. The results suggest that mice head exposed to heavy-ion radiation can induce damage and methylation pattern changed in distant organ liver. Moreover, our findings are important to understand the molecular mechanism of radiation induced bystander effects in vivo.