Investigating systematic individual differences in sleep-deprived performance on a high-fidelity flight simulator.

PubMed

Van Dongen, Hans P A; Caldwell, John A; Caldwell, J Lynn

2006-05-01

Laboratory research has revealed considerable systematic variability in the degree to which individuals' alertness and performance are affected by sleep deprivation. However, little is known about whether or not different populations exhibit similar levels of individual variability. In the present study, we examined individual variability in performance impairment due to sleep loss in a highly select population of militaryjet pilots. Ten active-duty F-117 pilots were deprived of sleep for 38 h and studied repeatedly in a high-fidelity flight simulator. Data were analyzed with a mixed-model ANOVA to quantify individual variability. Statistically significant, systematic individual differences in the effects of sleep deprivation were observed, even when baseline differences were accounted for. The findings suggest that highly select populations may exhibit individual differences in vulnerability to performance impairment from sleep loss just as the general population does. Thus, the scientific and operational communities' reliance on group data as opposed to individual data may entail substantial misestimation of the impact of job-related stressors on safety and performance.

Statistical methods and regression analysis of stratospheric ozone and meteorological variables in Isfahan

NASA Astrophysics Data System (ADS)

Hassanzadeh, S.; Hosseinibalam, F.; Omidvari, M.

2008-04-01

Data of seven meteorological variables (relative humidity, wet temperature, dry temperature, maximum temperature, minimum temperature, ground temperature and sun radiation time) and ozone values have been used for statistical analysis. Meteorological variables and ozone values were analyzed using both multiple linear regression and principal component methods. Data for the period 1999-2004 are analyzed jointly using both methods. For all periods, temperature dependent variables were highly correlated, but were all negatively correlated with relative humidity. Multiple regression analysis was used to fit the meteorological variables using the meteorological variables as predictors. A variable selection method based on high loading of varimax rotated principal components was used to obtain subsets of the predictor variables to be included in the linear regression model of the meteorological variables. In 1999, 2001 and 2002 one of the meteorological variables was weakly influenced predominantly by the ozone concentrations. However, the model did not predict that the meteorological variables for the year 2000 were not influenced predominantly by the ozone concentrations that point to variation in sun radiation. This could be due to other factors that were not explicitly considered in this study.

Bleeding complications and mortality in warfarin-treated VTE patients, dependence of INR variability and iTTR.

PubMed

Sandén, Per; Renlund, Henrik; Svensson, Peter J; Själander, Anders

2017-01-05

High quality of warfarin treatment is important to prevent recurrence of venous thromboembolism (VTE) without bleeding complications. The aim of this study was to examine the effect of individual time in therapeutic range (iTTR) and International Normalised Ratio (INR) variability on bleeding risk and mortality in a large cohort of well-managed patients with warfarin due to VTE. A cohort of 16612 patients corresponding to 19502 treatment periods with warfarin due to VTE between January 1, 2006 and December 31, 2011 was retrieved from the Swedish national quality register AuriculA and matched with the Swedish National Patient Register for bleeding complications and background characteristics and the Cause of death register for occurrence and date of death. The rate of bleeding was 1.79 (confidence interval (CI) 95 % 1.66-1.93) per 100 treatment years among all patients. Those with poor warfarin treatment quality had a higher rate of clinically relevant bleeding, both when measured as iTTR below 70 %, 2.91 (CI 95 % 2.61-3.21) or as INR variability over the mean value 0.85, 2.61 (CI 95 % 2.36-2.86). Among those with both high INR variability and low iTTR the risk of clinically relevant bleeding was clearly increased hazard ratio (HR) 3.47 (CI 95 % 2.89-4.17). A similar result was found for all-cause mortality with a HR of 3.67 (CI 95 % 3.02-4.47). Both a low iTTR and a high INR variability increase the risk of bleeding complications or mortality. When combining the two treatment quality indicators patients at particular high risk of bleeding or death can be identified.

Transposon Insertions, Structural Variations, and SNPs Contribute to the Evolution of the Melon Genome.

PubMed

Sanseverino, Walter; Hénaff, Elizabeth; Vives, Cristina; Pinosio, Sara; Burgos-Paz, William; Morgante, Michele; Ramos-Onsins, Sebastián E; Garcia-Mas, Jordi; Casacuberta, Josep Maria

2015-10-01

The availability of extensive databases of crop genome sequences should allow analysis of crop variability at an unprecedented scale, which should have an important impact in plant breeding. However, up to now the analysis of genetic variability at the whole-genome scale has been mainly restricted to single nucleotide polymorphisms (SNPs). This is a strong limitation as structural variation (SV) and transposon insertion polymorphisms are frequent in plant species and have had an important mutational role in crop domestication and breeding. Here, we present the first comprehensive analysis of melon genetic diversity, which includes a detailed analysis of SNPs, SV, and transposon insertion polymorphisms. The variability found among seven melon varieties representing the species diversity and including wild accessions and highly breed lines, is relatively high due in part to the marked divergence of some lineages. The diversity is distributed nonuniformly across the genome, being lower at the extremes of the chromosomes and higher in the pericentromeric regions, which is compatible with the effect of purifying selection and recombination forces over functional regions. Additionally, this variability is greatly reduced among elite varieties, probably due to selection during breeding. We have found some chromosomal regions showing a high differentiation of the elite varieties versus the rest, which could be considered as strongly selected candidate regions. Our data also suggest that transposons and SV may be at the origin of an important fraction of the variability in melon, which highlights the importance of analyzing all types of genetic variability to understand crop genome evolution. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Fourier resolved spectroscopy of 4U 1543-47 during the 2002 outburst

NASA Technical Reports Server (NTRS)

Reig, P.; Papadakis, I. E.; Shrader, C. R.; Kazanas, D.

2006-01-01

We have obtained Fourier-resolved spectra of the black-hole binary 4U 1543-47 in the canonical states (high/soft, very high, intermediate and low/hard) observed in this source during the decay of an outburst that took place in 2002. Our objective is to investigate the variability of the spectral components generally used to describe the energy spectra of black-hole systems, namely a disk component, a power-law component attributed to Comptonization by a hot corona and the contribution of the iron line due to reprocessing of the high energy (E greater than or approx, equal to 7 keV) radiation. We find that i) the disk component is not variable on time scales shorter than approx. 100 seconds, ii) the reprocessing emission as manifest by the variability of the Fe K(alpha) line responds to the primary radiation variations down to time scales of approx. 70 ms in the high and very-high states, but longer than 2 s in the low state, iii) the low-frequency QPOs are associated with variations of the X-ray power law spectral component and not to the disk component and iv) the spectra corresponding to the highest Fourier frequency are the hardest (show the flatter spectra) at a given spectral state. These results questions the models that explain the observed power spectra as due to modulations of the accretion rate only.

Spring snow conditions on Arctic sea ice north of Svalbard, during the Norwegian Young Sea ICE (N-ICE2015) expedition

NASA Astrophysics Data System (ADS)

Gallet, Jean-Charles; Merkouriadi, Ioanna; Liston, Glen E.; Polashenski, Chris; Hudson, Stephen; Rösel, Anja; Gerland, Sebastian

2017-10-01

Snow is crucial over sea ice due to its conflicting role in reflecting the incoming solar energy and reducing the heat transfer so that its temporal and spatial variability are important to estimate. During the Norwegian Young Sea ICE (N-ICE2015) campaign, snow physical properties and variability were examined, and results from April until mid-June 2015 are presented here. Overall, the snow thickness was about 20 cm higher than the climatology for second-year ice, with an average of 55 ± 27 cm and 32 ± 20 cm on first-year ice. The average density was 350-400 kg m-3 in spring, with higher values in June due to melting. Due to flooding in March, larger variability in snow water equivalent was observed. However, the snow structure was quite homogeneous in spring due to warmer weather and lower amount of storms passing over the field camp. The snow was mostly consisted of wind slab, faceted, and depth hoar type crystals with occasional fresh snow. These observations highlight the more dynamic character of evolution of snow properties over sea ice compared to previous observations, due to more variable sea ice and weather conditions in this area. The snowpack was isothermal as early as 10 June with the first onset of melt clearly identified in early June. Based on our observations, we estimate than snow could be accurately represented by a three to four layers modeling approach, in order to better consider the high variability of snow thickness and density together with the rapid metamorphose of the snow in springtime.

Genetics of the Shimokita macaque population suggest an ancient bottleneck.

PubMed

Kawamoto, Yoshi; Tomari, Ken-ichiro; Kawai, Shizuka; Kawamoto, Sakie

2008-01-01

The macaque population of the Shimokita Peninsula represents the northernmost distribution of this species and is isolated from other populations in the Tohoku region of Japan. A previous protein-based study revealed a high level of genetic variability in this population and considerable differentiation from other populations. In order to reassess the genetic features of the Shimokita macaques, we examined 11 autosomal microsatellite loci and three Y chromosomal microsatellite loci. We observed considerable differentiation from other Japanese populations of macaques, but in contrast to the previous results, we observed significantly lower genetic variability in this population. There was a weak indication of a population bottleneck, suggesting a decay over time from an excess of heterozygotes that might be expected in the initial stages of a bottleneck. This may indicate that an ancient bottleneck occurred during the warm period after the last glacial period rather than a recent bottleneck due to hunting in modern times. The frequencies of private alleles were exceptionally high in the Shimokita population, suggesting that the difference in variability as determined in various studies was due to accidental sampling of marker loci with low power to resolve genetic variations in the protein-based studies. The assessments of interpopulation differentiation as determined using autosomal and Y chromosomal markers were highly correlated, and using both types of markers the Shimokita population was found to be the most differentiated of the study populations, probably due to infrequent gene flow with surrounding populations.

Stochastic Lotka-Volterra equations: A model of lagged diffusion of technology in an interconnected world

NASA Astrophysics Data System (ADS)

Chakrabarti, Anindya S.

2016-01-01

We present a model of technological evolution due to interaction between multiple countries and the resultant effects on the corresponding macro variables. The world consists of a set of economies where some countries are leaders and some are followers in the technology ladder. All of them potentially gain from technological breakthroughs. Applying Lotka-Volterra (LV) equations to model evolution of the technology frontier, we show that the way technology diffuses creates repercussions in the partner economies. This process captures the spill-over effects on major macro variables seen in the current highly globalized world due to trickle-down effects of technology.

Variabilities in probabilistic seismic hazard maps for natural and induced seismicity in the central and eastern United States

USGS Publications Warehouse

Mousavi, S. Mostafa; Beroza, Gregory C.; Hoover, Susan M.

2018-01-01

Probabilistic seismic hazard analysis (PSHA) characterizes ground-motion hazard from earthquakes. Typically, the time horizon of a PSHA forecast is long, but in response to induced seismicity related to hydrocarbon development, the USGS developed one-year PSHA models. In this paper, we present a display of the variability in USGS hazard curves due to epistemic uncertainty in its informed submodel using a simple bootstrapping approach. We find that variability is highest in low-seismicity areas. On the other hand, areas of high seismic hazard, such as the New Madrid seismic zone or Oklahoma, exhibit relatively lower variability simply because of more available data and a better understanding of the seismicity. Comparing areas of high hazard, New Madrid, which has a history of large naturally occurring earthquakes, has lower forecast variability than Oklahoma, where the hazard is driven mainly by suspected induced earthquakes since 2009. Overall, the mean hazard obtained from bootstrapping is close to the published model, and variability increased in the 2017 one-year model relative to the 2016 model. Comparing the relative variations caused by individual logic-tree branches, we find that the highest hazard variation (as measured by the 95% confidence interval of bootstrapping samples) in the final model is associated with different ground-motion models and maximum magnitudes used in the logic tree, while the variability due to the smoothing distance is minimal. It should be pointed out that this study is not looking at the uncertainty in the hazard in general, but only as it is represented in the USGS one-year models.

Influence of seasonal and inter-annual hydro-meteorological variability on surface water fecal coliform concentration under varying land-use composition.

PubMed

St Laurent, Jacques; Mazumder, Asit

2014-01-01

Quantifying the influence of hydro-meteorological variability on surface source water fecal contamination is critical to the maintenance of safe drinking water. Historically, this has not been possible due to the scarcity of data on fecal indicator bacteria (FIB). We examined the relationship between hydro-meteorological variability and the most commonly measured FIB, fecal coliform (FC), concentration for 43 surface water sites within the hydro-climatologically complex region of British Columbia. The strength of relationship was highly variable among sites, but tended to be stronger in catchments with nival (snowmelt-dominated) hydro-meteorological regimes and greater land-use impacts. We observed positive relationships between inter-annual FC concentration and hydro-meteorological variability for around 50% of the 19 sites examined. These sites are likely to experience increased fecal contamination due to the projected intensification of the hydrological cycle. Seasonal FC concentration variability appeared to be driven by snowmelt and rainfall-induced runoff for around 30% of the 43 sites examined. Earlier snowmelt in nival catchments may advance the timing of peak contamination, and the projected decrease in annual snow-to-precipitation ratio is likely to increase fecal contamination levels during summer, fall, and winter among these sites. Safeguarding drinking water quality in the face of such impacts will require increased monitoring of FIB and waterborne pathogens, especially during periods of high hydro-meteorological variability. This data can then be used to develop predictive models, inform source water protection measures, and improve drinking water treatment. Copyright © 2013 Elsevier Ltd. All rights reserved.

The HEMP QSO Monitoring Project

NASA Astrophysics Data System (ADS)

Welsh, William F.; Robinson, E. L.

2000-02-01

Many AGN are highly variable sources. Some of these show a pronounced time delay between variations seen in their optical continuum and in their emission lines. ``Echo mapping'' is a technique that uses these time delays to measure the geometry and kinematics of the gas inside the AGN, near the supermassive black hole. The technique is immensely powerful, but the results so far have been modest due to relatively low quality data. We have initiated a long--term project to echo map QSOs. We will examine nearby (but intrinsically faint) QSOs as well as QSOs at high redshift. The high--z QSOs present a problem: it is not known ahead of time which of these are variable sources. Thus we have started a campaign to monitor about 60 high-redshift QSOs for the purpose of determining their variability characteristics. We request SSTO time on the 0.9m telescope for long--term monitoring of high--redshift QSOs to: (i) test their suitability as viable echo mapping candidates; and (ii) measure (for the first time) their variability properties, which is of intrinsic value itself.

Local-scale changes in mean and heavy precipitation in Western Europe, climate change or internal variability?

NASA Astrophysics Data System (ADS)

Aalbers, Emma E.; Lenderink, Geert; van Meijgaard, Erik; van den Hurk, Bart J. J. M.

2018-06-01

High-resolution climate information provided by e.g. regional climate models (RCMs) is valuable for exploring the changing weather under global warming, and assessing the local impact of climate change. While there is generally more confidence in the representativeness of simulated processes at higher resolutions, internal variability of the climate system—`noise', intrinsic to the chaotic nature of atmospheric and oceanic processes—is larger at smaller spatial scales as well, limiting the predictability of the climate signal. To quantify the internal variability and robustly estimate the climate signal, large initial-condition ensembles of climate simulations conducted with a single model provide essential information. We analyze a regional downscaling of a 16-member initial-condition ensemble over western Europe and the Alps at 0.11° resolution, similar to the highest resolution EURO-CORDEX simulations. We examine the strength of the forced climate response (signal) in mean and extreme daily precipitation with respect to noise due to internal variability, and find robust small-scale geographical features in the forced response, indicating regional differences in changes in the probability of events. However, individual ensemble members provide only limited information on the forced climate response, even for high levels of global warming. Although the results are based on a single RCM-GCM chain, we believe that they have general value in providing insight in the fraction of the uncertainty in high-resolution climate information that is irreducible, and can assist in the correct interpretation of fine-scale information in multi-model ensembles in terms of a forced response and noise due to internal variability.

Local-scale changes in mean and heavy precipitation in Western Europe, climate change or internal variability?

NASA Astrophysics Data System (ADS)

Aalbers, Emma E.; Lenderink, Geert; van Meijgaard, Erik; van den Hurk, Bart J. J. M.

2017-09-01

High-resolution climate information provided by e.g. regional climate models (RCMs) is valuable for exploring the changing weather under global warming, and assessing the local impact of climate change. While there is generally more confidence in the representativeness of simulated processes at higher resolutions, internal variability of the climate system—`noise', intrinsic to the chaotic nature of atmospheric and oceanic processes—is larger at smaller spatial scales as well, limiting the predictability of the climate signal. To quantify the internal variability and robustly estimate the climate signal, large initial-condition ensembles of climate simulations conducted with a single model provide essential information. We analyze a regional downscaling of a 16-member initial-condition ensemble over western Europe and the Alps at 0.11° resolution, similar to the highest resolution EURO-CORDEX simulations. We examine the strength of the forced climate response (signal) in mean and extreme daily precipitation with respect to noise due to internal variability, and find robust small-scale geographical features in the forced response, indicating regional differences in changes in the probability of events. However, individual ensemble members provide only limited information on the forced climate response, even for high levels of global warming. Although the results are based on a single RCM-GCM chain, we believe that they have general value in providing insight in the fraction of the uncertainty in high-resolution climate information that is irreducible, and can assist in the correct interpretation of fine-scale information in multi-model ensembles in terms of a forced response and noise due to internal variability.

VARIABILITY IN HOT CARBON-DOMINATED ATMOSPHERE (HOT DQ) WHITE DWARFS: RAPID ROTATION?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, Kurtis A.; Bierwagen, Michael; Montgomery, M. H.

2016-01-20

Hot white dwarfs (WDs) with carbon-dominated atmospheres (hot DQs) are a cryptic class of WDs. In addition to their deficiency of hydrogen and helium, most of these stars are highly magnetic, and a large fraction vary in luminosity. This variability has been ascribed to nonradial pulsations, but increasing data call this explanation into question. We present studies of short-term variability in seven hot DQ WDs. Three (SDSS J1426+5752, SDSS J2200−0741, and SDSS J2348−0942) were known to be variable. Their photometric modulations are coherent over at least two years, and we find no evidence for variability at frequencies that are notmore » harmonics. We present the first time-series photometry for three additional hot DQs (SDSS J0236−0734, SDSS J1402+3818, and SDSS J1615+4543); none are observed to vary, but the signal-to-noise is low. Finally, we present high speed photometry for SDSS J0005−1002, known to exhibit a 2.1-day photometric variation; we do not observe any short-term variability. Monoperiodicity is rare among pulsating WDs, so we contemplate whether the photometric variability is due to rotation rather than pulsations; similar hypotheses have been raised by other researchers. If the variability is due to rotation, then hot DQ WDs as a class contain many rapid rotators. Given the lack of companions to these stars, the origin of any fast rotation is unclear—both massive progenitor stars and double degenerate merger remnants are possibilities. We end with suggestions of future work that would best clarify the nature of these rare, intriguing objects.« less

The impact of inter-annual rainfall variability on African savannas changes with mean rainfall.

PubMed

Synodinos, Alexis D; Tietjen, Britta; Lohmann, Dirk; Jeltsch, Florian

2018-01-21

Savannas are mixed tree-grass ecosystems whose dynamics are predominantly regulated by resource competition and the temporal variability in climatic and environmental factors such as rainfall and fire. Hence, increasing inter-annual rainfall variability due to climate change could have a significant impact on savannas. To investigate this, we used an ecohydrological model of stochastic differential equations and simulated African savanna dynamics along a gradient of mean annual rainfall (520-780 mm/year) for a range of inter-annual rainfall variabilities. Our simulations produced alternative states of grassland and savanna across the mean rainfall gradient. Increasing inter-annual variability had a negative effect on the savanna state under dry conditions (520 mm/year), and a positive effect under moister conditions (580-780 mm/year). The former resulted from the net negative effect of dry and wet extremes on trees. In semi-arid conditions (520 mm/year), dry extremes caused a loss of tree cover, which could not be recovered during wet extremes because of strong resource competition and the increased frequency of fires. At high mean rainfall (780 mm/year), increased variability enhanced savanna resilience. Here, resources were no longer limiting and the slow tree dynamics buffered against variability by maintaining a stable population during 'dry' extremes, providing the basis for growth during wet extremes. Simultaneously, high rainfall years had a weak marginal benefit on grass cover due to density-regulation and grazing. Our results suggest that the effects of the slow tree and fast grass dynamics on tree-grass interactions will become a major determinant of the savanna vegetation composition with increasing rainfall variability. Copyright © 2017 Elsevier Ltd. All rights reserved.

Female homicide in Rio Grande do Sul, Brazil.

PubMed

Leites, Gabriela Tomedi; Meneghel, Stela Nazareth; Hirakata, Vania Noemi

2014-01-01

This study aimed to assess the female homicide rate due to aggression in Rio Grande do Sul, Brazil, using this as a "proxy" of femicide. This was an ecological study which correlated the female homicide rate due to aggression in Rio Grande do Sul, according to the 35 microregions defined by the Brazilian Institute of Geography and Statistics (IBGE), with socioeconomic and demographic variables access and health indicators. Pearson's correlation test was performed with the selected variables. After this, multiple linear regressions were performed with variables with p < 0.20. The standardized average of female homicide rate due to aggression in the period from 2003 to 2007 was 3.1 obits per 100 thousand. After multiple regression analysis, the final model included male mortality due to aggression (p = 0.016), the percentage of hospital admissions for alcohol (p = 0.005) and the proportion of ill-defined deaths (p = 0.015). The model have an explanatory power of 39% (adjusted r2 = 0.391). The results are consistent with other studies and indicate a strong relationship between structural violence in society and violence against women, in addition to a higher incidence of female deaths in places with high alcohol hospitalization.

Enhanced biennial variability in the Pacific due to Atlantic capacitor effect.

PubMed

Wang, Lei; Yu, Jin-Yi; Paek, Houk

2017-03-20

The El Niño-Southern Oscillation (ENSO) and the variability in the Pacific subtropical highs (PSHs) have major impacts on social and ecological systems. Here we present an Atlantic capacitor effect mechanism to suggest that the Atlantic is a key pacemaker of the biennial variability in the Pacific including that in ENSO and the PSHs during recent decades. The 'charging' (that is, ENSO imprinting the North Tropical Atlantic (NTA) sea surface temperature (SST) via an atmospheric bridge mechanism) and 'discharging' (that is, the NTA SST triggering the following ENSO via a subtropical teleconnection mechanism) processes alternate, generating the biennial rhythmic changes in the Pacific. Since the early 1990s, a warmer Atlantic due to the positive phase of Atlantic multidecadal oscillation and global warming trend has provided more favourable background state for the Atlantic capacitor effect, giving rise to enhanced biennial variability in the Pacific that may increase the occurrence frequency of severe natural hazard events.

Enhanced biennial variability in the Pacific due to Atlantic capacitor effect

PubMed Central

Wang, Lei; Yu, Jin-Yi; Paek, Houk

2017-01-01

The El Niño-Southern Oscillation (ENSO) and the variability in the Pacific subtropical highs (PSHs) have major impacts on social and ecological systems. Here we present an Atlantic capacitor effect mechanism to suggest that the Atlantic is a key pacemaker of the biennial variability in the Pacific including that in ENSO and the PSHs during recent decades. The ‘charging' (that is, ENSO imprinting the North Tropical Atlantic (NTA) sea surface temperature (SST) via an atmospheric bridge mechanism) and ‘discharging' (that is, the NTA SST triggering the following ENSO via a subtropical teleconnection mechanism) processes alternate, generating the biennial rhythmic changes in the Pacific. Since the early 1990s, a warmer Atlantic due to the positive phase of Atlantic multidecadal oscillation and global warming trend has provided more favourable background state for the Atlantic capacitor effect, giving rise to enhanced biennial variability in the Pacific that may increase the occurrence frequency of severe natural hazard events. PMID:28317857

Enhanced biennial variability in the Pacific due to Atlantic capacitor effect

NASA Astrophysics Data System (ADS)

Wang, Lei; Yu, Jin-Yi; Paek, Houk

2017-03-01

The El Niño-Southern Oscillation (ENSO) and the variability in the Pacific subtropical highs (PSHs) have major impacts on social and ecological systems. Here we present an Atlantic capacitor effect mechanism to suggest that the Atlantic is a key pacemaker of the biennial variability in the Pacific including that in ENSO and the PSHs during recent decades. The `charging' (that is, ENSO imprinting the North Tropical Atlantic (NTA) sea surface temperature (SST) via an atmospheric bridge mechanism) and `discharging' (that is, the NTA SST triggering the following ENSO via a subtropical teleconnection mechanism) processes alternate, generating the biennial rhythmic changes in the Pacific. Since the early 1990s, a warmer Atlantic due to the positive phase of Atlantic multidecadal oscillation and global warming trend has provided more favourable background state for the Atlantic capacitor effect, giving rise to enhanced biennial variability in the Pacific that may increase the occurrence frequency of severe natural hazard events.

Effect of inter- and intra-annual thermohaline variability on acoustic propagation

NASA Astrophysics Data System (ADS)

Chu, Peter C.; McDonald, Colleen M.; Kucukosmanoglu, Murat; Judono, Albert; Margolina, Tetyana; Fan, Chenwu

2017-05-01

This paper is to answer the question "How can inter- and intra-annual variability in the ocean be leveraged by the submarine Force?" through quantifying inter- and intra-annual variability in (T, S) fields and in turn underwater acoustic characteristics such as transmission loss, signal excess, and range of detection. The Navy's Generalized Digital Environmental Model (GDEM) is the climatological monthly mean data and represents mean annual variability. An optimal spectral decomposition method is used to produce a synoptic monthly gridded (SMG) (T, S) dataset for the world oceans with 1° ×1° horizontal resolution, 28 vertical levels (surface to 3,000 m depth), monthly time increment from January 1945 to December 2014 now available at the NOAA/NCEI website: http://data.nodc.noaa.gov/cgibin/iso?id=gov.noaa.nodc:0140938. The sound velocity decreases from 1945 to 1975 and increases afterwards due to global climate change. Effect of the inter- and intra-annual (T, S) variability on acoustic propagation in the Yellow Sea is investigated using a well-developed acoustic model (Bellhop) in frequencies from 3.5 kHz to 5 kHz with sound velocity profile (SVP) calculated from GDEM and SMG datasets, various bottom types (silty clay, fine sand, gravelly mud, sandy mud, and cobble or gravel) from the NAVOCEANO`s High Frequency Environmental Algorithms (HFEVA), source and receiver depths. Acoustic propagation ranges are extended drastically due to the inter-annual variability in comparison with the climatological SVP (from GDEM). Submarines' vulnerability of detection as its depth varies and avoidance of short acoustic range due to inter-annual variability are also discussed.

Acclimatization of the crustose coralline alga Porolithon onkodes to variable pCO₂.

PubMed

Johnson, Maggie D; Moriarty, Vincent W; Carpenter, Robert C

2014-01-01

Ocean acidification (OA) has important implications for the persistence of coral reef ecosystems, due to potentially negative effects on biomineralization. Many coral reefs are dynamic with respect to carbonate chemistry, and experience fluctuations in pCO₂ that exceed OA projections for the near future. To understand the influence of dynamic pCO₂ on an important reef calcifier, we tested the response of the crustose coralline alga Porolithon onkodes to oscillating pCO₂. Individuals were exposed to ambient (400 µatm), high (660 µatm), or variable pCO₂ (oscillating between 400/660 µatm) treatments for 14 days. To explore the potential for coralline acclimatization, we collected individuals from low and high pCO₂ variability sites (upstream and downstream respectively) on a back reef characterized by unidirectional water flow in Moorea, French Polynesia. We quantified the effects of treatment on algal calcification by measuring the change in buoyant weight, and on algal metabolism by conducting sealed incubations to measure rates of photosynthesis and respiration. Net photosynthesis was higher in the ambient treatment than the variable treatment, regardless of habitat origin, and there was no effect on respiration or gross photosynthesis. Exposure to high pCO₂ decreased P. onkodes calcification by >70%, regardless of the original habitat. In the variable treatment, corallines from the high variability habitat calcified 42% more than corallines from the low variability habitat. The significance of the original habitat for the coralline calcification response to variable, high pCO₂ indicates that individuals existing in dynamic pCO₂ habitats may be acclimatized to OA within the scope of in situ variability. These results highlight the importance of accounting for natural pCO₂ variability in OA manipulations, and provide insight into the potential for plasticity in habitat and species-specific responses to changing ocean chemistry.

The future demographic niche of a declining grassland bird fails to shift poleward in response to climate change

Treesearch

Lisa A. McCauley; Christine A. Ribic; Lars Y. Pomara; Benjamin Zuckerberg

2017-01-01

Context Temperate grasslands and their dependent species are exposed to high variability in weather and climate due to the lack of natural buffers such as forests. Grassland birds are particularly vulnerable to this variability, yet have failed to shift poleward in response to recent climate change like other bird species in North America. However, there have been few...

A dynamic aerodynamic resistance approach to calculate high resolution sensible heat fluxes in urban areas

NASA Astrophysics Data System (ADS)

Crawford, Ben; Grimmond, Sue; Kent, Christoph; Gabey, Andrew; Ward, Helen; Sun, Ting; Morrison, William

2017-04-01

Remotely sensed data from satellites have potential to enable high-resolution, automated calculation of urban surface energy balance terms and inform decisions about urban adaptations to environmental change. However, aerodynamic resistance methods to estimate sensible heat flux (QH) in cities using satellite-derived observations of surface temperature are difficult in part due to spatial and temporal variability of the thermal aerodynamic resistance term (rah). In this work, we extend an empirical function to estimate rah using observational data from several cities with a broad range of surface vegetation land cover properties. We then use this function to calculate spatially and temporally variable rah in London based on high-resolution (100 m) land cover datasets and in situ meteorological observations. In order to calculate high-resolution QH based on satellite-observed land surface temperatures, we also develop and employ novel methods to i) apply source area-weighted averaging of surface and meteorological variables across the study spatial domain, ii) calculate spatially variable, high-resolution meteorological variables (wind speed, friction velocity, and Obukhov length), iii) incorporate spatially interpolated urban air temperatures from a distributed sensor network, and iv) apply a modified Monte Carlo approach to assess uncertainties with our results, methods, and input variables. Modeled QH using the aerodynamic resistance method is then compared to in situ observations in central London from a unique network of scintillometers and eddy-covariance measurements.

Individual aptitude in Mandarin lexical tone perception predicts effectiveness of high-variability training

PubMed Central

Sadakata, Makiko; McQueen, James M.

2014-01-01

Although the high-variability training method can enhance learning of non-native speech categories, this can depend on individuals’ aptitude. The current study asked how general the effects of perceptual aptitude are by testing whether they occur with training materials spoken by native speakers and whether they depend on the nature of the to-be-learned material. Forty-five native Dutch listeners took part in a 5-day training procedure in which they identified bisyllabic Mandarin pseudowords (e.g., asa) pronounced with different lexical tone combinations. The training materials were presented to different groups of listeners at three levels of variability: low (many repetitions of a limited set of words recorded by a single speaker), medium (fewer repetitions of a more variable set of words recorded by three speakers), and high (similar to medium but with five speakers). Overall, variability did not influence learning performance, but this was due to an interaction with individuals’ perceptual aptitude: increasing variability hindered improvements in performance for low-aptitude perceivers while it helped improvements in performance for high-aptitude perceivers. These results show that the previously observed interaction between individuals’ aptitude and effects of degree of variability extends to natural tokens of Mandarin speech. This interaction was not found, however, in a closely matched study in which native Dutch listeners were trained on the Japanese geminate/singleton consonant contrast. This may indicate that the effectiveness of high-variability training depends not only on individuals’ aptitude in speech perception but also on the nature of the categories being acquired. PMID:25505434

On the nature of the high-energy rollover in 1H 0419-577

NASA Astrophysics Data System (ADS)

Turner, T. J.; Reeves, J. N.; Braito, V.; Costa, M.

2018-05-01

A NuSTAR/Swift observation of the luminous Seyfert 1 galaxy 1H 0419-577 taken during 2015 reveals one of the most extreme high-energy cut-offs observed to date from an AGN - an origin due to thermal Comptonization would imply a remarkably low coronal temperature kT ˜ 15 keV. The low-energy peak of the spectrum in the hard X-ray NuSTAR band, which peaks before the expected onset of a Compton hump, rules out strong reflection as the origin of the hard excess in this AGN. We show the origin of the high-energy rollover is likely due to a combination of both thermal Comptonization and an intrinsically steeper continuum, which is modified by absorption at lower energies. Furthermore, modelling the broad-band XUV continuum shape as a colour-corrected accretion disc, requires the presence of a variable warm absorber to explain all flux and spectral states of the source, consistent with the previous work on this AGN. While absorber variations produce marked spectral variability in this AGN, consideration of all flux states allows us to isolate a colourless component of variability that may arise from changes in the inner accretion flow, typically at around 10 rg.

Femicides: female homicide in Brazil.

PubMed

Meneghel, Stela Nazareth; Hirakata, Vania Naomi

2011-06-01

To assess female homicide rates due to aggression according to sociodemographic and health indicators. Ecological study on female homicides due to aggression in Brazil between 2003 and 2007. Information on 19,459 deaths were obtained form the Brazilian Mortality Database. Standardized female homicide rates due to aggression were correlated with 28 socioeconomic, demographic and health indicators, using Pearson's correlation test. Multiple linear regression was performed including variables with p < 0.20 and excluding those with multicollinearity. The standardized female homicide rate due to aggression was 4.1/100,000 during the study period. After adjustment, three variables remained significantly associated with female homicides: birth rate (p = 0.072), percentage of Evangelicals (p = 0.019) and male homicides due to aggression (p < 0.001). The model had a predictive power of 69% (r² = 0.699). The Brazilian states of Espírito Santo, Pernambuco, Mato Grosso, Rio de Janeiro, Rondônia, Alagoas, Mato Grosso do Sul, Roraima e Amapá showed the highest rates during the study period. The female homicide rates due to aggression were high in Brazil and varied by region. The association with male homicides due to aggression stresses the importance of reducing structural violence to protect women against violence.

Short-term meso-scale variability of mesozooplankton communities in a coastal upwelling system (NW Spain)

NASA Astrophysics Data System (ADS)

Roura, Álvaro; Álvarez-Salgado, Xosé A.; González, Ángel F.; Gregori, María; Rosón, Gabriel; Guerra, Ángel

2013-02-01

The short-term, meso-scale variability of the mesozooplankton community present in the coastal upwelling system of the Ría de Vigo (NW Spain) has been analysed. Three well-defined communities were identified: coastal, frontal and oceanic, according to their holoplankton-meroplankton ratio, richness, and total abundance. These communities changed from summer to autumn due to a shift from downwelling to upwelling-favourable conditions coupled with taxa dependent changes in life strategies. Relationships between the resemblance matrix of mesozooplankton and the resemblance matrices of meteorologic, hydrographic and community-derived biotic variables were determined with distance-based linear models (DistLM, 18 variables), showing an increasing amount of explained variability of 6%, 16.1% and 54.5%, respectively. A simplified model revealed that the variability found in the resemblance matrix of mesozooplankton was mainly described by the holoplankton-meroplankton ratio, the total abundance, the influence of lunar cycles, the upwelling index and the richness; altogether accounting for 64% of the total variability. The largest variability of the mesozooplankton resemblance matrix (39.6%) is accounted by the holoplankton-meroplankton ratio, a simple index that describes appropriately the coastal-ocean gradient. The communities described herein kept their integrity in the studied upwelling and downwelling episodes in spite of the highly advective environment off the Ría de Vigo, presumably due to behavioural changes in the vertical position of the zooplankton.

Interannual variability and climatic noise in satellite-observed outgoing longwave radiation

NASA Technical Reports Server (NTRS)

Short, D. A.; Cahalan, R. F.

1983-01-01

Upwelling-IR observations of the North Pacific by polar orbiters NOAA 3, 4, 5, and 6 and TIROS-N from 1974 to 1981 are analyzed statistically in terms of interannual variability (IAV) in monthly averages and climatic noise due to short-term weather fluctuations. It is found that although the daily variance in the observations is the same in summer and winter months, and although IAV in winter is smaller than that in summer, the climatic noise in winter is so much smaller that a greater fraction of winter anomalies are statistically significant. The smaller winter climatic noise level is shown to be due to shorter autocorrelation times. It is demonstrated that increasing averaging area does not reduce the climatic noise level, suggesting that continuing collection of high-resolution satellite IR data on a global basis is necessary if better models of short-term variability are to be constructed.

Optimized MPPT algorithm for boost converters taking into account the environmental variables

NASA Astrophysics Data System (ADS)

Petit, Pierre; Sawicki, Jean-Paul; Saint-Eve, Frédéric; Maufay, Fabrice; Aillerie, Michel

2016-07-01

This paper presents a study on the specific behavior of the Boost DC-DC converters generally used for powering conversion of PV panels connected to a HVDC (High Voltage Direct Current) Bus. It follows some works pointing out that converter MPPT (Maximum Power Point Tracker) is severely perturbed by output voltage variations due to physical dependency of parameters as the input voltage, the output voltage and the duty cycle of the PWM switching control of the MPPT. As a direct consequence many converters connected together on a same load perturb each other because of the output voltage variations induced by fluctuations on the HVDC bus essentially due to a not insignificant bus impedance. In this paper we show that it is possible to include an internal computed variable in charge to compensate local and external variations to take into account the environment variables.

The 4 phase VSR motor: The ideal prime mover for electric vehicles

DOE Office of Scientific and Technical Information (OSTI.GOV)

Holling, G.H.; Yeck, M.M.

1994-12-31

4 phase variable switched reluctance motors are gaining acceptance in many applications due to their fault tolerant characteristics. A 4 phase variable switched reluctance motor (VSR) is modelled and its performance is predicted for several operating points for an electric vehicle application. The 4 phase VSR offers fault tolerance, high performance, and an excellent torque to weight ratio. The actual system performance was measured both on a teststand and on an actual vehicle. While the system described is used in a production electric motorscooter, the technology is equally applicable for high efficiency electric cars and buses. 4 refs.

Continuous-variable controlled-Z gate using an atomic ensemble

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang Mingfeng; Jiang Nianquan; Jin Qingli

2011-06-15

The continuous-variable controlled-Z gate is a canonical two-mode gate for universal continuous-variable quantum computation. It is considered as one of the most fundamental continuous-variable quantum gates. Here we present a scheme for realizing continuous-variable controlled-Z gate between two optical beams using an atomic ensemble. The gate is performed by simply sending the two beams propagating in two orthogonal directions twice through a spin-squeezed atomic medium. Its fidelity can run up to one if the input atomic state is infinitely squeezed. Considering the noise effects due to atomic decoherence and light losses, we show that the observed fidelities of the schememore » are still quite high within presently available techniques.« less

Framework for making better predictions by directly estimating variables' predictivity.

PubMed

Lo, Adeline; Chernoff, Herman; Zheng, Tian; Lo, Shaw-Hwa

2016-12-13

We propose approaching prediction from a framework grounded in the theoretical correct prediction rate of a variable set as a parameter of interest. This framework allows us to define a measure of predictivity that enables assessing variable sets for, preferably high, predictivity. We first define the prediction rate for a variable set and consider, and ultimately reject, the naive estimator, a statistic based on the observed sample data, due to its inflated bias for moderate sample size and its sensitivity to noisy useless variables. We demonstrate that the [Formula: see text]-score of the PR method of VS yields a relatively unbiased estimate of a parameter that is not sensitive to noisy variables and is a lower bound to the parameter of interest. Thus, the PR method using the [Formula: see text]-score provides an effective approach to selecting highly predictive variables. We offer simulations and an application of the [Formula: see text]-score on real data to demonstrate the statistic's predictive performance on sample data. We conjecture that using the partition retention and [Formula: see text]-score can aid in finding variable sets with promising prediction rates; however, further research in the avenue of sample-based measures of predictivity is much desired.

Population genetic structure of a California endemic Branchiopod, Branchinecta sandiegonensis

USGS Publications Warehouse

Davies, Cathleen P.; Simovich, Marie A.; Hathaway, Stacie A.

1997-01-01

Branchinecta sandiegonensis (Crustacea: Anostraca) is a narrow range endemic fairy shrimp discontinuously distributed in ephemeral pools on coastal mesas in San Diego County, USA. Ten populations across the range of the species were subjected to allozyme analysis for eleven loci. The species exhibits low variability (P95 =9.1–45.5) and one third of the loci tested did not conform to Hardy-Weinberg equilibrium expectations. The species also exhibited a high degree of genetic differentiation between populations. F ST values (fixation index) for most pairs of populations were above 0.25 (0.036–0.889).Low genetic variability and high genetic structure may result from low gene flow and founder effects due to habitat fragmentation and the lack of potential vectors for cyst dispersal. The unpredictable rainfall of the region also creates potential for variable population sizes which could affect structure and variability.

Dentition of moustached tamarins (Saguinus mystax mystax) from Padre Isla, Peru, part 1: quantitative variation.

PubMed

Tornow, Matthew A; Ford, Susan M; Garber, Paul A; de Sa Sauerbrunn, Edward

2006-07-01

Analyses of dental variation in geographically restricted, wild populations of primates are extremely rare; however, such data form the best source for models of likely degrees of variation within and between fossil species. Data from dental casts of a geographically restricted population of moustached tamarins (Saguinus mystax mystax) from Padre Isla, Peru, document high levels of dental variability, as measured by coefficients of variation, in a nonsexually dimorphic species, despite its isolation and small population size. Like other primates, moustached tamarins show lower variability in the dimensions of the first molars and increased variability in the dimensions of the final molars in the toothrow. Moustached tamarins from Padre Isla have a distinctive pattern of variability in the remaining teeth, including more stable tooth lengths in the anterior and posterior portions of the toothrow, and more stable tooth widths in the midregion of the toothrow. High variability in incisor width may be due to age effects of a distinctive diet and pattern of dental wear.

The near-infrared counterpart of a variable galactic plane radio source

NASA Technical Reports Server (NTRS)

Margon, Bruce; Phillips, Andrew C.; Ciardullo, Robin; Jacoby, George H.

1992-01-01

A near-infrared counterpart to the highly variable, unresolved galactic plane radio source GT 0116 + 622 is identified. This source is of particular interest, as it has been previously suggested to be the counterpart of the gamma-ray source Cas gamma-l. The present NIR and red images detect a faint, spatially extended (3 arcsec FWHM), very red object coincident with the radio position. There is complex spatial structure which may be due in part to an unrelated superposed foreground object. Observations on multiple nights show no evidence for flux variability, despite the high amplitude variability on a time-scale of days reported for the radio source. The data are consistent with an interpretation of GT 0116 + 622 as an unusually variable, obscured active galaxy at a distance of several hundred megaparsecs, although more exotic, and in particular galactic, interpretations cannot yet be ruled out. If the object is extragalactic, the previously suggested identification with the gamma-ray source would seem unlikely.

RNA-seq: technical variability and sampling

PubMed Central

2011-01-01

Background RNA-seq is revolutionizing the way we study transcriptomes. mRNA can be surveyed without prior knowledge of gene transcripts. Alternative splicing of transcript isoforms and the identification of previously unknown exons are being reported. Initial reports of differences in exon usage, and splicing between samples as well as quantitative differences among samples are beginning to surface. Biological variation has been reported to be larger than technical variation. In addition, technical variation has been reported to be in line with expectations due to random sampling. However, strategies for dealing with technical variation will differ depending on the magnitude. The size of technical variance, and the role of sampling are examined in this manuscript. Results In this study three independent Solexa/Illumina experiments containing technical replicates are analyzed. When coverage is low, large disagreements between technical replicates are apparent. Exon detection between technical replicates is highly variable when the coverage is less than 5 reads per nucleotide and estimates of gene expression are more likely to disagree when coverage is low. Although large disagreements in the estimates of expression are observed at all levels of coverage. Conclusions Technical variability is too high to ignore. Technical variability results in inconsistent detection of exons at low levels of coverage. Further, the estimate of the relative abundance of a transcript can substantially disagree, even when coverage levels are high. This may be due to the low sampling fraction and if so, it will persist as an issue needing to be addressed in experimental design even as the next wave of technology produces larger numbers of reads. We provide practical recommendations for dealing with the technical variability, without dramatic cost increases. PMID:21645359

Harmonization of texture and skid-resistance measurements.

DOT National Transportation Integrated Search

2008-09-30

Due to safety concerns associated with friction testing on both high and low-speed facilities, testing at variable speeds has been previously investigated by the Florida DOT. The American Society for Testing and materials (ASTM) has endorsed this con...

Increases in Parent Attendance to Behavioral Parent Training Due to Concurrent Child Treatment Groups

ERIC Educational Resources Information Center

Jensen, Scott A.; Grimes, Lisa K.

2010-01-01

Though behavioral parent training has been demonstrated to be an effective intervention for child behavior problems, it continues to suffer from high attrition rates. Few variables have been found to predict or decrease high attrition rates from parent training classes. The present study found 43-52% increases in attendance rates for parents whose…

High Temperature Tribometer. Phase 1

DTIC Science & Technology

1989-06-01

13 Figure 2.3.2 Setpoint and Gain Windows in FW.EXE ......... . Figure 2.4.1 Data-Flow Diagram for Data-Acquisition Module ..... .. 23 I Figure...mounted in a friction force measuring device. Optimally , material testing results should not be test machine sensitiye; but due to equipment variables...fixed. The friction force due to sliding should be continuously measured. This is optimally done in conjunction with the normal force measurement via

Spatiotemporal variation in heat-related out-of-hospital cardiac arrest during the summer in Japan.

PubMed

Onozuka, Daisuke; Hagihara, Akihito

2017-04-01

Although several studies have reported the impacts of extremely high temperature on cardiovascular diseases, few studies have investigated the spatiotemporal variation in the incidence of out-of-hospital cardiac arrest (OHCA) due to extremely high temperature in Japan. Daily OHCA data from 2005 to 2014 were acquired from all 47 prefectures of Japan. We used time-series Poisson regression analysis combined with a distributed lag non-linear model to assess the temporal variability in the effects of extremely high temperature on OHCA incidence in each prefecture, adjusted for time trends. Spatial variability in the relationships between extremely high temperature and OHCA between prefectures was estimated using a multivariate random-effects meta-analysis. We analyzed 166,496 OHCA cases of presumed cardiac origin occurring during the summer (June to September) that met the inclusion criteria. The minimum morbidity percentile (MMP) was the 51st percentile of temperature during the summer in Japan. The overall cumulative relative risk at the 99th percentile vs. the MMP over lags 0-10days was 1.21 (95% CI: 1.12-1.31). There was also a strong low temperature effect during the summer periods. No substantial difference in spatial or temporal variability was observed over the study period. Our study demonstrated spatiotemporal homogeneity in the risk of OHCA during periods of extremely high temperature between 2005 and 2014 in Japan. Our findings suggest that public health strategies for OHCA due to extremely high temperatures should be finely adjusted and should particularly account for the unchanging risk during the summer. Copyright © 2017 Elsevier B.V. All rights reserved.

NON-POINT SOURCE POLLUTION

EPA Science Inventory

Non-point source pollution is a diffuse source that is difficult to measure and is highly variable due to different rain patterns and other climatic conditions. In many areas, however, non-point source pollution is the greatest source of water quality degradation. Presently, stat...

Integrating Solar PV in Utility System Operations: Analytical Framework and Arizona Case Study

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, Jing; Botterud, Audun; Mills, Andrew

2015-06-01

A systematic framework is proposed to estimate the impact on operating costs due to uncertainty and variability in renewable resources. The framework quantifies the integration costs associated with subhourly variability and uncertainty as well as day-ahead forecasting errors in solar PV (photovoltaics) power. A case study illustrates how changes in system operations may affect these costs for a utility in the southwestern United States (Arizona Public Service Company). We conduct an extensive sensitivity analysis under different assumptions about balancing reserves, system flexibility, fuel prices, and forecasting errors. We find that high solar PV penetrations may lead to operational challenges, particularlymore » during low-load and high solar periods. Increased system flexibility is essential for minimizing integration costs and maintaining reliability. In a set of sensitivity cases where such flexibility is provided, in part, by flexible operations of nuclear power plants, the estimated integration costs vary between $1.0 and $4.4/MWh-PV for a PV penetration level of 17%. The integration costs are primarily due to higher needs for hour-ahead balancing reserves to address the increased sub-hourly variability and uncertainty in the PV resource. (C) 2015 Elsevier Ltd. All rights reserved.« less

Establishing the Global Fresh Water Sensor Web

NASA Technical Reports Server (NTRS)

Hildebrand, Peter H.

2005-01-01

This paper presents an approach to measuring the major components of the water cycle from space using the concept of a sensor-web of satellites that are linked to a data assimilation system. This topic is of increasing importance, due to the need for fresh water to support the growing human population, coupled with climate variability and change. The net effect is that water is an increasingly valuable commodity. The distribution of fresh water is highly uneven over the Earth, with both strong latitudinal distributions due to the atmospheric general circulation, and even larger variability due to landforms and the interaction of land with global weather systems. The annual global fresh water budget is largely a balance between evaporation, atmospheric transport, precipitation and runoff. Although the available volume of fresh water on land is small, the short residence time of water in these fresh water reservoirs causes the flux of fresh water - through evaporation, atmospheric transport, precipitation and runoff - to be large. With a total atmospheric water store of approx. 13 x 10(exp 12)cu m, and an annual flux of approx. 460 x 10(exp 12)cu m/y, the mean atmospheric residence time of water is approx. 10 days. River residence times are similar, biological are approx. 1 week, soil moisture is approx. 2 months, and lakes and aquifers are highly variable, extending from weeks to years. The hypothesized potential for redistribution and acceleration of the global hydrological cycle is therefore of concern. This hypothesized speed-up - thought to be associated with global warming - adds to the pressure placed upon water resources by the burgeoning human population, the variability of weather and climate, and concerns about anthropogenic impacts on global fresh water availability.

Response of ENSO amplitude to global warming in CESM large ensemble: uncertainty due to internal variability

NASA Astrophysics Data System (ADS)

Zheng, Xiao-Tong; Hui, Chang; Yeh, Sang-Wook

2018-06-01

El Niño-Southern Oscillation (ENSO) is the dominant mode of variability in the coupled ocean-atmospheric system. Future projections of ENSO change under global warming are highly uncertain among models. In this study, the effect of internal variability on ENSO amplitude change in future climate projections is investigated based on a 40-member ensemble from the Community Earth System Model Large Ensemble (CESM-LE) project. A large uncertainty is identified among ensemble members due to internal variability. The inter-member diversity is associated with a zonal dipole pattern of sea surface temperature (SST) change in the mean along the equator, which is similar to the second empirical orthogonal function (EOF) mode of tropical Pacific decadal variability (TPDV) in the unforced control simulation. The uncertainty in CESM-LE is comparable in magnitude to that among models of the Coupled Model Intercomparison Project phase 5 (CMIP5), suggesting the contribution of internal variability to the intermodel uncertainty in ENSO amplitude change. However, the causations between changes in ENSO amplitude and the mean state are distinct between CESM-LE and CMIP5 ensemble. The CESM-LE results indicate that a large ensemble of 15 members is needed to separate the relative contributions to ENSO amplitude change over the twenty-first century between forced response and internal variability.

Identification of Important Process Variables for Fiber Spinning of Protein Nanotubes Generated from Waste Materials

DTIC Science & Technology

2012-01-11

nanotubes , which sold at the same current cost as carbon nanotubes , this would equate to a $788 million industry. In the USA, the potential to source eye...advantages over carbon nanotubes due to the ability to functionalized them 31. The nanotubes are a highly ordered, insoluble form of protein. Fibrils...1756 Identification of important process variables for fiber spinning of protein nanotubes generated from waste materials. Research Team (listed

Climatically driven yield variability of major crops in Khakassia (South Siberia)

NASA Astrophysics Data System (ADS)

Babushkina, Elena A.; Belokopytova, Liliana V.; Zhirnova, Dina F.; Shah, Santosh K.; Kostyakova, Tatiana V.

2018-06-01

We investigated the variability of yield of the three main crop cultures in the Khakassia Republic: spring wheat, spring barley, and oats. In terms of yield values, variability characteristics, and climatic response, the agricultural territory of Khakassia can be divided into three zones: (1) the Northern Zone, where crops yield has a high positive response to the amount of precipitation, May-July, and a moderately negative one to the temperatures of the same period; (2) the Central Zone, where crops yield depends mainly on temperatures; and (3) the Southern Zone, where climate has the least expressed impact on yield. The dominant pattern in the crops yield is caused by water stress during periods of high temperatures and low moisture supply with heat stress as additional reason. Differences between zones are due to combinations of temperature latitudinal gradient, precipitation altitudinal gradient, and the presence of a well-developed hydrological network and the irrigational system as moisture sources in the Central Zone. More detailed analysis shows differences in the climatic sensitivity of crops during phases of their vegetative growth and grain development and, to a lesser extent, during harvesting period. Multifactor linear regression models were constructed to estimate climate- and autocorrelation-induced variability of the crops yield. These models allowed prediction of the possibility of yield decreasing by at least 2-11% in the next decade due to increasing of the regional summer temperatures.

Robust optimization of a tandem grating solar thermal absorber

NASA Astrophysics Data System (ADS)

Choi, Jongin; Kim, Mingeon; Kang, Kyeonghwan; Lee, Ikjin; Lee, Bong Jae

2018-04-01

Ideal solar thermal absorbers need to have a high value of the spectral absorptance in the broad solar spectrum to utilize the solar radiation effectively. Majority of recent studies about solar thermal absorbers focus on achieving nearly perfect absorption using nanostructures, whose characteristic dimension is smaller than the wavelength of sunlight. However, precise fabrication of such nanostructures is not easy in reality; that is, unavoidable errors always occur to some extent in the dimension of fabricated nanostructures, causing an undesirable deviation of the absorption performance between the designed structure and the actually fabricated one. In order to minimize the variation in the solar absorptance due to the fabrication error, the robust optimization can be performed during the design process. However, the optimization of solar thermal absorber considering all design variables often requires tremendous computational costs to find an optimum combination of design variables with the robustness as well as the high performance. To achieve this goal, we apply the robust optimization using the Kriging method and the genetic algorithm for designing a tandem grating solar absorber. By constructing a surrogate model through the Kriging method, computational cost can be substantially reduced because exact calculation of the performance for every combination of variables is not necessary. Using the surrogate model and the genetic algorithm, we successfully design an effective solar thermal absorber exhibiting a low-level of performance degradation due to the fabrication uncertainty of design variables.

Climatically driven yield variability of major crops in Khakassia (South Siberia)

NASA Astrophysics Data System (ADS)

Babushkina, Elena A.; Belokopytova, Liliana V.; Zhirnova, Dina F.; Shah, Santosh K.; Kostyakova, Tatiana V.

2017-12-01

We investigated the variability of yield of the three main crop cultures in the Khakassia Republic: spring wheat, spring barley, and oats. In terms of yield values, variability characteristics, and climatic response, the agricultural territory of Khakassia can be divided into three zones: (1) the Northern Zone, where crops yield has a high positive response to the amount of precipitation, May-July, and a moderately negative one to the temperatures of the same period; (2) the Central Zone, where crops yield depends mainly on temperatures; and (3) the Southern Zone, where climate has the least expressed impact on yield. The dominant pattern in the crops yield is caused by water stress during periods of high temperatures and low moisture supply with heat stress as additional reason. Differences between zones are due to combinations of temperature latitudinal gradient, precipitation altitudinal gradient, and the presence of a well-developed hydrological network and the irrigational system as moisture sources in the Central Zone. More detailed analysis shows differences in the climatic sensitivity of crops during phases of their vegetative growth and grain development and, to a lesser extent, during harvesting period. Multifactor linear regression models were constructed to estimate climate- and autocorrelation-induced variability of the crops yield. These models allowed prediction of the possibility of yield decreasing by at least 2-11% in the next decade due to increasing of the regional summer temperatures.

A downscaling scheme for atmospheric variables to drive soil-vegetation-atmosphere transfer models

NASA Astrophysics Data System (ADS)

Schomburg, A.; Venema, V.; Lindau, R.; Ament, F.; Simmer, C.

2010-09-01

For driving soil-vegetation-transfer models or hydrological models, high-resolution atmospheric forcing data is needed. For most applications the resolution of atmospheric model output is too coarse. To avoid biases due to the non-linear processes, a downscaling system should predict the unresolved variability of the atmospheric forcing. For this purpose we derived a disaggregation system consisting of three steps: (1) a bi-quadratic spline-interpolation of the low-resolution data, (2) a so-called `deterministic' part, based on statistical rules between high-resolution surface variables and the desired atmospheric near-surface variables and (3) an autoregressive noise-generation step. The disaggregation system has been developed and tested based on high-resolution model output (400m horizontal grid spacing). A novel automatic search-algorithm has been developed for deriving the deterministic downscaling rules of step 2. When applied to the atmospheric variables of the lowest layer of the atmospheric COSMO-model, the disaggregation is able to adequately reconstruct the reference fields. Applying downscaling step 1 and 2, root mean square errors are decreased. Step 3 finally leads to a close match of the subgrid variability and temporal autocorrelation with the reference fields. The scheme can be applied to the output of atmospheric models, both for stand-alone offline simulations, and a fully coupled model system.

Framework for making better predictions by directly estimating variables’ predictivity

PubMed Central

Chernoff, Herman; Lo, Shaw-Hwa

2016-01-01

We propose approaching prediction from a framework grounded in the theoretical correct prediction rate of a variable set as a parameter of interest. This framework allows us to define a measure of predictivity that enables assessing variable sets for, preferably high, predictivity. We first define the prediction rate for a variable set and consider, and ultimately reject, the naive estimator, a statistic based on the observed sample data, due to its inflated bias for moderate sample size and its sensitivity to noisy useless variables. We demonstrate that the I-score of the PR method of VS yields a relatively unbiased estimate of a parameter that is not sensitive to noisy variables and is a lower bound to the parameter of interest. Thus, the PR method using the I-score provides an effective approach to selecting highly predictive variables. We offer simulations and an application of the I-score on real data to demonstrate the statistic’s predictive performance on sample data. We conjecture that using the partition retention and I-score can aid in finding variable sets with promising prediction rates; however, further research in the avenue of sample-based measures of predictivity is much desired. PMID:27911830

Variability of textural features in FDG PET images due to different acquisition modes and reconstruction parameters.

PubMed

Galavis, Paulina E; Hollensen, Christian; Jallow, Ngoneh; Paliwal, Bhudatt; Jeraj, Robert

2010-10-01

Characterization of textural features (spatial distributions of image intensity levels) has been considered as a tool for automatic tumor segmentation. The purpose of this work is to study the variability of the textural features in PET images due to different acquisition modes and reconstruction parameters. Twenty patients with solid tumors underwent PET/CT scans on a GE Discovery VCT scanner, 45-60 minutes post-injection of 10 mCi of [(18)F]FDG. Scans were acquired in both 2D and 3D modes. For each acquisition the raw PET data was reconstructed using five different reconstruction parameters. Lesions were segmented on a default image using the threshold of 40% of maximum SUV. Fifty different texture features were calculated inside the tumors. The range of variations of the features were calculated with respect to the average value. Fifty textural features were classified based on the range of variation in three categories: small, intermediate and large variability. Features with small variability (range ≤ 5%) were entropy-first order, energy, maximal correlation coefficient (second order feature) and low-gray level run emphasis (high-order feature). The features with intermediate variability (10% ≤ range ≤ 25%) were entropy-GLCM, sum entropy, high gray level run emphsis, gray level non-uniformity, small number emphasis, and entropy-NGL. Forty remaining features presented large variations (range > 30%). Textural features such as entropy-first order, energy, maximal correlation coefficient, and low-gray level run emphasis exhibited small variations due to different acquisition modes and reconstruction parameters. Features with low level of variations are better candidates for reproducible tumor segmentation. Even though features such as contrast-NGTD, coarseness, homogeneity, and busyness have been previously used, our data indicated that these features presented large variations, therefore they could not be considered as a good candidates for tumor segmentation.

Variability of textural features in FDG PET images due to different acquisition modes and reconstruction parameters

PubMed Central

GALAVIS, PAULINA E.; HOLLENSEN, CHRISTIAN; JALLOW, NGONEH; PALIWAL, BHUDATT; JERAJ, ROBERT

2014-01-01

Background Characterization of textural features (spatial distributions of image intensity levels) has been considered as a tool for automatic tumor segmentation. The purpose of this work is to study the variability of the textural features in PET images due to different acquisition modes and reconstruction parameters. Material and methods Twenty patients with solid tumors underwent PET/CT scans on a GE Discovery VCT scanner, 45–60 minutes post-injection of 10 mCi of [18F]FDG. Scans were acquired in both 2D and 3D modes. For each acquisition the raw PET data was reconstructed using five different reconstruction parameters. Lesions were segmented on a default image using the threshold of 40% of maximum SUV. Fifty different texture features were calculated inside the tumors. The range of variations of the features were calculated with respect to the average value. Results Fifty textural features were classified based on the range of variation in three categories: small, intermediate and large variability. Features with small variability (range ≤ 5%) were entropy-first order, energy, maximal correlation coefficient (second order feature) and low-gray level run emphasis (high-order feature). The features with intermediate variability (10% ≤ range ≤ 25%) were entropy-GLCM, sum entropy, high gray level run emphsis, gray level non-uniformity, small number emphasis, and entropy-NGL. Forty remaining features presented large variations (range > 30%). Conclusion Textural features such as entropy-first order, energy, maximal correlation coefficient, and low-gray level run emphasis exhibited small variations due to different acquisition modes and reconstruction parameters. Features with low level of variations are better candidates for reproducible tumor segmentation. Even though features such as contrast-NGTD, coarseness, homogeneity, and busyness have been previously used, our data indicated that these features presented large variations, therefore they could not be considered as a good candidates for tumor segmentation. PMID:20831489

TraitEnactments as Density Distributions: The Role of Actors, Situations, and Observers in Explaining Stability and Variability

PubMed Central

Fleeson, William; Law, Mary Kate

2015-01-01

The purposes of this paper were to determine (i)whether the high consistency of individual differences in average aggregated behavior is due to actors’ personalities or to consistency in the situations those actors encounter; and(ii)whether the surprisingly high within-person variability in trait enactment is a real phenomenon corroborated by observers, or merely in individuals’ heads. Although traits are supposed to describe what individuals are like in everyday life, little evidence exists about the enactment of trait content in everyday life. Past experience-sampling studies have found both highly variable and highly consistent trait enactment, but were restricted to self-report data and to naturally occurring situations. The current study used experience-sampling in controlled lab environments with 97 targets and 183 observers to address these shortcomings. Targets attended hour-long lab sessions 20x each and observers rated targets’ behavior. Parameters of distributions were highly consistent (r’s ~ .80), revealing that actors were responsible for consistency, not situations. Nonetheless, observer ratings revealed that most variability in trait enactment was within-person, confirming that even when people put it on the line in ways that affect others, they still varied rapidly in the traits they enacted. In the face of two historically vexing objections to traits, this paper supports the density distributions model of traits and argues that trait conceptualizations must accommodate large within-person variability. PMID:26348598

Variability and performance evaluation of introgressed Nigerian dura x Deli dura oil palm progenies.

PubMed

Noh, A; Rafii, M Y; Mohd Din, A; Kushairi, A; Norziha, A; Rajanaidu, N; Latif, M A; Malek, M A

2014-04-03

Twelve introgressed oil palm (Elaeis guineensis) progenies of Nigerian dura x Deli dura were evaluated for bunch yield, yield attributes, bunch quality components and vegetative characters at the Malaysian Palm Oil Board Research Station, in Keratong, Pahang, Malaysia. Analysis of variance revealed significant to highly significant genotypic differences, indicating sufficient genetic variability among the progenies for bunch yield and its attributes, vegetative characters and bunch quality components, except fruit to bunch ratio. Fresh fruit bunch yield ranged from 167 kg·palm(-1)·year(-1) in PK1330 to 212 kg·palm(-1)·year(-1) in PK1351, with a mean yield of 192 kg·palm(-1)·year(-1). Among the progeny, PK1313 had the highest oil to bunch ratio (19.36%), due to its high mesocarp to fruit ratio, fruit to bunch ratio and low shell to fruit ratio. Among the progenies, PK1313 produced the highest oil yield of 31.4 kg·palm(-1)·year(-1), due to a high mesocarp to fruit ratio (61.2%) and a low shell to fruit ratio (30.7%), coupled with high fruit to bunch ratio (65.6%). PK1330 was found promising for selection, as it had desirable vegetative characters, including smaller petiole cross section (27.15 cm2), short rachis length (4.83 m), short palm height (1.85 m), and the lowest leaf number (164.6), as these vegetative characters are prerequisites for selecting palms for high density planting and high yield per hectare. The genetic variability among the progenies was found to be high, indicating ample scope for further breeding, followed by selection.

ATMOSPHERIC AEROSOLS FROM BIOGENIC HYDROCARBON OXIDATION

EPA Science Inventory

Our review of published research on SQT emissions revealed a high variability of methods used by different researchers. Given that SQT have rather low vapor pressures, they tend to easily adhere (‘stick’) to surfaces used in experimental systems. Also, due to their...

Biogeochemical typology and temporal variability of lagoon waters in a coral reef ecosystem subject to terrigeneous and anthropogenic inputs (New Caledonia).

PubMed

Fichez, R; Chifflet, S; Douillet, P; Gérard, P; Gutierrez, F; Jouon, A; Ouillon, S; Grenz, C

2010-01-01

Considering the growing concern about the impact of anthropogenic inputs on coral reefs and coral reef lagoons, surprisingly little attention has been given to the relationship between those inputs and the trophic status of lagoon waters. The present paper describes the distribution of biogeochemical parameters in the coral reef lagoon of New Caledonia where environmental conditions allegedly range from pristine oligotrophic to anthropogenically influenced. The study objectives were to: (i) identify terrigeneous and anthropogenic inputs and propose a typology of lagoon waters, (ii) determine temporal variability of water biogeochemical parameters at time-scales ranging from hours to seasons. Combined ACP-cluster analyses revealed that over the 2000 km(2) lagoon area around the city of Nouméa, "natural" terrigeneous versus oceanic influences affecting all stations only accounted for less than 20% of the spatial variability whereas 60% of that spatial variability could be attributed to significant eutrophication of a limited number of inshore stations. ACP analysis allowed to unambiguously discriminating between the natural trophic enrichment along the offshore-inshore gradient and anthropogenically induced eutrophication. High temporal variability in dissolved inorganic nutrients concentrations strongly hindered their use as indicators of environmental status. Due to longer turn over time, particulate organic material and more specifically chlorophyll a appeared as more reliable nonconservative tracer of trophic status. Results further provided evidence that ENSO occurrences might temporarily lower the trophic status of the New Caledonia lagoon. It is concluded that, due to such high frequency temporal variability, the use of biogeochemical parameters in environmental surveys require adapted sampling strategies, data management and environmental alert methods. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

Nature of global large-scale sea level variability in relation to atmospheric forcing: A modeling study

NASA Astrophysics Data System (ADS)

Fukumori, Ichiro; Raghunath, Ramanujam; Fu, Lee-Lueng

1998-03-01

The relation between large-scale sea level variability and ocean circulation is studied using a numerical model. A global primitive equation model of the ocean is forced by daily winds and climatological heat fluxes corresponding to the period from January 1992 to January 1994. The physical nature of sea level's temporal variability from periods of days to a year is examined on the basis of spectral analyses of model results and comparisons with satellite altimetry and tide gauge measurements. The study elucidates and diagnoses the inhomogeneous physics of sea level change in space and frequency domain. At midlatitudes, large-scale sea level variability is primarily due to steric changes associated with the seasonal heating and cooling cycle of the surface layer. In comparison, changes in the tropics and high latitudes are mainly wind driven. Wind-driven variability exhibits a strong latitudinal dependence in itself. Wind-driven changes are largely baroclinic in the tropics but barotropic at higher latitudes. Baroclinic changes are dominated by the annual harmonic of the first baroclinic mode and is largest off the equator; variabilities associated with equatorial waves are smaller in comparison. Wind-driven barotropic changes exhibit a notable enhancement over several abyssal plains in the Southern Ocean, which is likely due to resonant planetary wave modes in basins semienclosed by discontinuities in potential vorticity. Otherwise, barotropic sea level changes are typically dominated by high frequencies with as much as half the total variance in periods shorter than 20 days, reflecting the frequency spectra of wind stress curl. Implications of the findings with regards to analyzing observations and data assimilation are discussed.

Atmospheric icing of structures: Observations and simulations

NASA Astrophysics Data System (ADS)

Ágústsson, H.; Elíasson, Á. J.; Thorsteins, E.; Rögnvaldsson, Ó.; Ólafsson, H.

2012-04-01

This study compares observed icing in a test span in complex orography at Hallormsstaðaháls (575 m) in East-Iceland with parameterized icing based on an icing model and dynamically downscaled weather at high horizontal resolution. Four icing events have been selected from an extensive dataset of observed atmospheric icing in Iceland. A total of 86 test-spans have been erected since 1972 at 56 locations in complex terrain with more than 1000 icing events documented. The events used here have peak observed ice load between 4 and 36 kg/m. Most of the ice accretion is in-cloud icing but it may partly be mixed with freezing drizzle and wet snow icing. The calculation of atmospheric icing is made in two steps. First the atmospheric data is created by dynamically downscaling the ECMWF-analysis to high resolution using the non-hydrostatic mesoscale Advanced Research WRF-model. The horizontal resolution of 9, 3, 1 and 0.33 km is necessary to allow the atmospheric model to reproduce correctly local weather in the complex terrain of Iceland. Secondly, the Makkonen-model is used to calculate the ice accretion rate on the conductors based on the simulated temperature, wind, cloud and precipitation variables from the atmospheric data. In general, the atmospheric model correctly simulates the atmospheric variables and icing calculations based on the atmospheric variables correctly identify the observed icing events, but underestimate the load due to too slow ice accretion. This is most obvious when the temperature is slightly below 0°C and the observed icing is most intense. The model results improve significantly when additional observations of weather from an upstream weather station are used to nudge the atmospheric model. However, the large variability in the simulated atmospheric variables results in high temporal and spatial variability in the calculated ice accretion. Furthermore, there is high sensitivity of the icing model to the droplet size and the possibility that some of the icing may be due to freezing drizzle or wet snow instead of in-cloud icing of super-cooled droplets. In addition, the icing model (Makkonen) may not be accurate for the highest icing loads observed.

Acclimatization of the Crustose Coralline Alga Porolithon onkodes to Variable pCO2

PubMed Central

Johnson, Maggie D.; Moriarty, Vincent W.; Carpenter, Robert C.

2014-01-01

Ocean acidification (OA) has important implications for the persistence of coral reef ecosystems, due to potentially negative effects on biomineralization. Many coral reefs are dynamic with respect to carbonate chemistry, and experience fluctuations in pCO2 that exceed OA projections for the near future. To understand the influence of dynamic pCO2 on an important reef calcifier, we tested the response of the crustose coralline alga Porolithon onkodes to oscillating pCO2. Individuals were exposed to ambient (400 µatm), high (660 µatm), or variable pCO2 (oscillating between 400/660 µatm) treatments for 14 days. To explore the potential for coralline acclimatization, we collected individuals from low and high pCO2 variability sites (upstream and downstream respectively) on a back reef characterized by unidirectional water flow in Moorea, French Polynesia. We quantified the effects of treatment on algal calcification by measuring the change in buoyant weight, and on algal metabolism by conducting sealed incubations to measure rates of photosynthesis and respiration. Net photosynthesis was higher in the ambient treatment than the variable treatment, regardless of habitat origin, and there was no effect on respiration or gross photosynthesis. Exposure to high pCO2 decreased P. onkodes calcification by >70%, regardless of the original habitat. In the variable treatment, corallines from the high variability habitat calcified 42% more than corallines from the low variability habitat. The significance of the original habitat for the coralline calcification response to variable, high pCO2 indicates that individuals existing in dynamic pCO2 habitats may be acclimatized to OA within the scope of in situ variability. These results highlight the importance of accounting for natural pCO2 variability in OA manipulations, and provide insight into the potential for plasticity in habitat and species-specific responses to changing ocean chemistry. PMID:24505305

Wildland fire emissions, carbon, and climate: U.S. emissions inventories

Treesearch

Narasimhan K. Larkin; Sean M. Raffuse; Tara M. Strand

2014-01-01

Emissions from wildland fire are both highly variable and highly uncertain over a wide range of temporal and spatial scales. Wildland fire emissions change considerably due to fluctuations from year to year with overall fire season severity, from season to season as different regions pass in and out of wildfire and prescribed fire periods, and from day to day as...

Investigating the effect and uncertainties of light absorbing impurities in snow and ice on snow melt and discharge generation using a hydrologic catchment model and satellite data

NASA Astrophysics Data System (ADS)

Matt, Felix; Burkhart, John F.

2017-04-01

Light absorbing impurities in snow and ice (LAISI) originating from atmospheric deposition enhance snow melt by increasing the absorption of short wave radiation. The consequences are a shortening of the snow cover duration due to increased snow melt and, with respect to hydrologic processes, a temporal shift in the discharge generation. However, the magnitude of these effects as simulated in numerical models have large uncertainties, originating mainly from uncertainties in the wet and dry deposition of light absorbing aerosols, limitations in the model representation of the snowpack, and the lack of observable variables required to estimate model parameters and evaluate the simulated variables connected with the representation of LAISI. This leads to high uncertainties in the additional energy absorbed by the snow due to the presence of LAISI, a key variable in understanding snowpack energy-balance dynamics. In this study, we assess the effect of LAISI on snow melt and discharge generation and the involved uncertainties in a high mountain catchment located in the western Himalayas by using a distributed hydrological catchment model with focus on the representation of the seasonal snow pack. The snow albedo is hereby calculated from a radiative transfer model for snow, taking the increased absorption of short wave radiation by LAISI into account. Meteorological forcing data is generated from an assimilation of observations and high resolution WRF simulations, and LAISI mixing ratios from deposition rates of Black Carbon simulated with the FLEXPART model. To asses the quality of our simulations and the related uncertainties, we compare the simulated additional energy absorbed by the snow due to the presence of LAISI to the MODIS Dust Radiative Forcing in Snow (MODDRFS) algorithm satellite product.

Using a respiratory navigator significantly reduces variability when quantifying left ventricular torsion with cardiovascular magnetic resonance.

PubMed

Hamlet, Sean M; Haggerty, Christopher M; Suever, Jonathan D; Wehner, Gregory J; Andres, Kristin N; Powell, David K; Charnigo, Richard J; Fornwalt, Brandon K

2017-03-01

Left ventricular (LV) torsion is an important indicator of cardiac function that is limited by high inter-test variability (50% of the mean value). We hypothesized that this high inter-test variability is partly due to inconsistent breath-hold positions during serial image acquisitions, which could be significantly improved by using a respiratory navigator for cardiovascular magnetic resonance (CMR) based quantification of LV torsion. We assessed respiratory-related variability in measured LV torsion with two distinct experimental protocols. First, 17 volunteers were recruited for CMR with cine displacement encoding with stimulated echoes (DENSE) in which a respiratory navigator was used to measure and then enforce variability in end-expiratory position between all LV basal and apical acquisitions. From these data, we quantified the inter-test variability of torsion in the absence and presence of enforced end-expiratory position variability, which established an upper bound for the expected torsion variability. For the second experiment (in 20 new, healthy volunteers), 10 pairs of cine DENSE basal and apical images were each acquired from consecutive breath-holds and consecutive navigator-gated scans (with a single acceptance position). Inter-test variability of torsion was compared between the breath-hold and navigator-gated scans to quantify the variability due to natural breath-hold variation. To demonstrate the importance of these variability reductions, we quantified the reduction in sample size required to detect a clinically meaningful change in LV torsion with the use of a respiratory navigator. The mean torsion was 3.4 ± 0.2°/cm. From the first experiment, enforced variability in end-expiratory position translated to considerable variability in measured torsion (0.56 ± 0.34°/cm), whereas inter-test variability with consistent end-expiratory position was 57% lower (0.24 ± 0.16°/cm, p < 0.001). From the second experiment, natural respiratory variability from consecutive breath-holds translated to a variability in torsion of 0.24 ± 0.10°/cm, which was significantly higher than the variability from navigator-gated scans (0.18 ± 0.06°/cm, p = 0.02). By using a respiratory navigator with DENSE, theoretical sample sizes were reduced from 66 to 16 and 26 to 15 as calculated from the two experiments. A substantial portion (22-57%) of the inter-test variability of LV torsion can be reduced by using a respiratory navigator to ensure a consistent breath-hold position between image acquisitions.

Low vibration high numerical aperture automated variable temperature Raman microscope

DOE PAGES

Tian, Y.; Reijnders, A. A.; Osterhoudt, G. B.; ...

2016-04-05

Raman micro-spectroscopy is well suited for studying a variety of properties and has been applied to wide- ranging areas. Combined with tuneable temperature, Raman spectra can offer even more insights into the properties of materials. However, previous designs of variable temperature Raman microscopes have made it extremely challenging to measure samples with low signal levels due to thermal and positional instability as well as low collection efficiencies. Thus, contemporary Raman microscope has found limited applicability to probing the subtle physics involved in phase transitions and hysteresis. This paper describes a new design of a closed-cycle, Raman microscope with full polarizationmore » rotation. High collection efficiency, thermal and mechanical stability are ensured by both deliberate optical, cryogenic, and mechanical design. Measurements on two samples, Bi 2Se 3 and V 2O 3, which are known as challenging due to low thermal conductivities, low signal levels and/or hysteretic effects, are measured with previously undemonstrated temperature resolution.« less

Families at financial risk due to high ratio of out-of-pocket health care expenditures to total income.

PubMed

Bennett, Kevin J; Dismuke, Clara E

2010-05-01

High out-of-pocket expenditures for health care can put individuals and families at financial risk. Several groups, including racial/ethnic minority groups, the uninsured, rural residents, and those in poorer health are at risk for this increased burden. The analysis utilized 2004-2005 MEPS data. The dependent variables were the out-of-pocket health care spending to total income ratios for total spending, office-based visits, and prescription drugs. Multivariate analyses with instrumental variables controlled for respondent characteristics. Gender, age, rurality, insurance coverage, health status, and health care utilization were all associated with higher out-of-pocket to income ratios. Certain groups, such as women, the elderly, those in poor health, and rural residents, are at a greater financial risk due to their higher out-of-pocket to total income spending ratios. Policymakers must be aware of these increased risks in order to provide adequate resources and targeted interventions to alleviate some of this burden.

Low vibration high numerical aperture automated variable temperature Raman microscope

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tian, Y.; Reijnders, A. A.; Osterhoudt, G. B.

Raman micro-spectroscopy is well suited for studying a variety of properties and has been applied to wide- ranging areas. Combined with tuneable temperature, Raman spectra can offer even more insights into the properties of materials. However, previous designs of variable temperature Raman microscopes have made it extremely challenging to measure samples with low signal levels due to thermal and positional instability as well as low collection efficiencies. Thus, contemporary Raman microscope has found limited applicability to probing the subtle physics involved in phase transitions and hysteresis. This paper describes a new design of a closed-cycle, Raman microscope with full polarizationmore » rotation. High collection efficiency, thermal and mechanical stability are ensured by both deliberate optical, cryogenic, and mechanical design. Measurements on two samples, Bi 2Se 3 and V 2O 3, which are known as challenging due to low thermal conductivities, low signal levels and/or hysteretic effects, are measured with previously undemonstrated temperature resolution.« less

The relationship between wind power, electricity demand and winter weather patterns in Great Britain

NASA Astrophysics Data System (ADS)

Thornton, Hazel E.; Scaife, Adam A.; Hoskins, Brian J.; Brayshaw, David J.

2017-06-01

Wind power generation in Great Britain has increased markedly in recent years. However due to its intermittency its ability to provide power during periods of high electricity demand has been questioned. Here we characterise the winter relationship between electricity demand and the availability of wind power. Although a wide range of wind power capacity factors is seen for a given demand, the average capacity factor reduces by a third between low and high demand. However, during the highest demand average wind power increases again, due to strengthening easterly winds. The nature of the weather patterns affecting Great Britain are responsible for this relationship. High demand is driven by a range of high pressure weather types, each giving cold conditions, but variable wind power availability. Offshore wind power is sustained at higher levels and offers a more secure supply compared to that onshore. However, during high demand periods in Great Britain neighbouring countries may struggle to provide additional capacity due to concurrent low temperatures and low wind power availability.

Nonlocal Intracranial Cavity Extraction

PubMed Central

Manjón, José V.; Eskildsen, Simon F.; Coupé, Pierrick; Romero, José E.; Collins, D. Louis; Robles, Montserrat

2014-01-01

Automatic and accurate methods to estimate normalized regional brain volumes from MRI data are valuable tools which may help to obtain an objective diagnosis and followup of many neurological diseases. To estimate such regional brain volumes, the intracranial cavity volume (ICV) is often used for normalization. However, the high variability of brain shape and size due to normal intersubject variability, normal changes occurring over the lifespan, and abnormal changes due to disease makes the ICV estimation problem challenging. In this paper, we present a new approach to perform ICV extraction based on the use of a library of prelabeled brain images to capture the large variability of brain shapes. To this end, an improved nonlocal label fusion scheme based on BEaST technique is proposed to increase the accuracy of the ICV estimation. The proposed method is compared with recent state-of-the-art methods and the results demonstrate an improved performance both in terms of accuracy and reproducibility while maintaining a reduced computational burden. PMID:25328511

Damage accumulation of bovine bone under variable amplitude loads.

PubMed

Campbell, Abbey M; Cler, Michelle L; Skurla, Carolyn P; Kuehl, Joseph J

2016-12-01

Stress fractures, a painful injury, are caused by excessive fatigue in bone. This study on damage accumulation in bone sought to determine if the Palmgren-Miner rule (PMR), a well-known linear damage accumulation hypothesis, is predictive of fatigue failure in bone. An electromagnetic shaker apparatus was constructed to conduct cyclic and variable amplitude tests on bovine bone specimens. Three distinct damage regimes were observed following fracture. Fractures due to a low cyclic amplitude loading appeared ductile ( 4000 μ ϵ ), brittle due to high cyclic amplitude loading (> 9000 μ ϵ ), and a combination of ductile and brittle from mid-range cyclic amplitude loading (6500 -6750 μ ϵ ). Brittle and ductile fracture mechanisms were isolated and mixed, in a controlled way, into variable amplitude loading tests. PMR predictions of cycles to failure consistently over-predicted fatigue life when mixing isolated fracture mechanisms. However, PMR was not proven ineffective when used with a single damage mechanism.

Coralline algal Barium as indicator for 20th century northwestern North Atlantic surface ocean freshwater variability

PubMed Central

Hetzinger, S.; Halfar, J.; Zack, T.; Mecking, J. V.; Kunz, B. E.; Jacob, D. E.; Adey, W. H.

2013-01-01

During the past decades climate and freshwater dynamics in the northwestern North Atlantic have undergone major changes. Large-scale freshening episodes, related to polar freshwater pulses, have had a strong influence on ocean variability in this climatically important region. However, little is known about variability before 1950, mainly due to the lack of long-term high-resolution marine proxy archives. Here we present the first multidecadal-length records of annually resolved Ba/Ca variations from Northwest Atlantic coralline algae. We observe positive relationships between algal Ba/Ca ratios from two Newfoundland sites and salinity observations back to 1950. Both records capture episodical multi-year freshening events during the 20th century. Variability in algal Ba/Ca is sensitive to freshwater-induced changes in upper ocean stratification, which affect the transport of cold, Ba-enriched deep waters onto the shelf (highly stratified equals less Ba/Ca). Algal Ba/Ca ratios therefore may serve as a new resource for reconstructing past surface ocean freshwater changes. PMID:23636135

Coralline algal barium as indicator for 20th century northwestern North Atlantic surface ocean freshwater variability.

PubMed

Hetzinger, S; Halfar, J; Zack, T; Mecking, J V; Kunz, B E; Jacob, D E; Adey, W H

2013-01-01

During the past decades climate and freshwater dynamics in the northwestern North Atlantic have undergone major changes. Large-scale freshening episodes, related to polar freshwater pulses, have had a strong influence on ocean variability in this climatically important region. However, little is known about variability before 1950, mainly due to the lack of long-term high-resolution marine proxy archives. Here we present the first multidecadal-length records of annually resolved Ba/Ca variations from Northwest Atlantic coralline algae. We observe positive relationships between algal Ba/Ca ratios from two Newfoundland sites and salinity observations back to 1950. Both records capture episodical multi-year freshening events during the 20th century. Variability in algal Ba/Ca is sensitive to freshwater-induced changes in upper ocean stratification, which affect the transport of cold, Ba-enriched deep waters onto the shelf (highly stratified equals less Ba/Ca). Algal Ba/Ca ratios therefore may serve as a new resource for reconstructing past surface ocean freshwater changes.

Climate variability and extremes, interacting with nitrogen storage, amplify eutrophication risk

USGS Publications Warehouse

Lee, Minjin; Shevliakova, Elena; Malyshev, Sergey; Milly, P.C.D.; Jaffe, Peter R.

2016-01-01

Despite 30 years of basin-wide nutrient-reduction efforts, severe hypoxia continues to be observed in the Chesapeake Bay. Here we demonstrate the critical influence of climate variability, interacting with accumulated nitrogen (N) over multidecades, on Susquehanna River dissolved nitrogen (DN) loads, known precursors of the hypoxia in the Bay. We used the process model LM3-TAN (Terrestrial and Aquatic Nitrogen), which is capable of capturing both seasonal and decadal-to-century changes in vegetation-soil-river N storage, and produced nine scenarios of DN-load distributions under different short-term scenarios of climate variability and extremes. We illustrate that after 1 to 3 yearlong dry spells, the likelihood of exceeding a threshold DN load (56 kt yr−1) increases by 40 to 65% due to flushing of N accumulated throughout the dry spells and altered microbial processes. Our analyses suggest that possible future increases in climate variability/extremes—specifically, high precipitation occurring after multiyear dry spells—could likely lead to high DN-load anomalies and hypoxia.

Control approach development for variable recruitment artificial muscles

NASA Astrophysics Data System (ADS)

Jenkins, Tyler E.; Chapman, Edward M.; Bryant, Matthew

2016-04-01

This study characterizes hybrid control approaches for the variable recruitment of fluidic artificial muscles with double acting (antagonistic) actuation. Fluidic artificial muscle actuators have been explored by researchers due to their natural compliance, high force-to-weight ratio, and low cost of fabrication. Previous studies have attempted to improve system efficiency of the actuators through variable recruitment, i.e. using discrete changes in the number of active actuators. While current variable recruitment research utilizes manual valve switching, this paper details the current development of an online variable recruitment control scheme. By continuously controlling applied pressure and discretely controlling the number of active actuators, operation in the lowest possible recruitment state is ensured and working fluid consumption is minimized. Results provide insight into switching control scheme effects on working fluids, fabrication material choices, actuator modeling, and controller development decisions.

Subject order-independent group ICA (SOI-GICA) for functional MRI data analysis.

PubMed

Zhang, Han; Zuo, Xi-Nian; Ma, Shuang-Ye; Zang, Yu-Feng; Milham, Michael P; Zhu, Chao-Zhe

2010-07-15

Independent component analysis (ICA) is a data-driven approach to study functional magnetic resonance imaging (fMRI) data. Particularly, for group analysis on multiple subjects, temporally concatenation group ICA (TC-GICA) is intensively used. However, due to the usually limited computational capability, data reduction with principal component analysis (PCA: a standard preprocessing step of ICA decomposition) is difficult to achieve for a large dataset. To overcome this, TC-GICA employs multiple-stage PCA data reduction. Such multiple-stage PCA data reduction, however, leads to variable outputs due to different subject concatenation orders. Consequently, the ICA algorithm uses the variable multiple-stage PCA outputs and generates variable decompositions. In this study, a rigorous theoretical analysis was conducted to prove the existence of such variability. Simulated and real fMRI experiments were used to demonstrate the subject-order-induced variability of TC-GICA results using multiple PCA data reductions. To solve this problem, we propose a new subject order-independent group ICA (SOI-GICA). Both simulated and real fMRI data experiments demonstrated the high robustness and accuracy of the SOI-GICA results compared to those of traditional TC-GICA. Accordingly, we recommend SOI-GICA for group ICA-based fMRI studies, especially those with large data sets. Copyright 2010 Elsevier Inc. All rights reserved.

Vaccine development for protection against systemic infections with Streptococcus suis and Haemophilus parasuis in swine

USDA-ARS?s Scientific Manuscript database

Both Streptococcus suis and Haemophilus parasuis are important invasive bacterial pathogens of swine, commonly causing meningitis, arthritis, polyserositis, and septicemia. Due to the presence of many serotypes and high genotypic variability, efficacious vaccines are not readily available. We are us...

First Results on the Variability of Mid- and High-Latitude Ionospheric Electric Fields at 1- Second Time Scales

NASA Astrophysics Data System (ADS)

Ruohoniemi, J. M.; Greenwald, R. A.; Oksavik, K.; Baker, J. B.

2007-12-01

The electric fields at high latitudes are often modeled as a static pattern in the absence of variation in solar wind parameters or geomagnetic disturbance. However, temporal variability in the local electric fields on time scales of minutes for stable conditions has been reported and characterized statistically as an intrinsic property amounting to turbulence. We describe the results of applying a new technique to SuperDARN HF radar observations of ionospheric plasma convection at middle and high latitudes that gives views of the variability of the electric fields at sub-second time scales. We address the question of whether there is a limit to the temporal scale of the electric field variability and consider whether the turbulence on minute time scales is due to organized but unresolved behavior. The basis of the measurements is the ability to record raw samples from the individual multipulse sequences that are transmitted during the standard 3 or 6-second SuperDARN integration period; a backscattering volume is then effectively sampled at a cadence of 200 ms. The returns from the individual sequences are often sufficiently well-ordered to permit a sequence-by-sequence characterization of the electric field and backscattered power. We attempt a statistical characterization of the variability at these heretofore inaccessible time scales and consider how variability is influenced by solar wind and magentospheric factors.

Light valve based on nonimaging optics with potential application in cold climate greenhouses

NASA Astrophysics Data System (ADS)

Valerio, Angel A.; Mossman, Michele A.; Whitehead, Lorne A.

2014-09-01

We have evaluated a new concept for a variable light valve and thermal insulation system based on nonimaging optics. The system incorporates compound parabolic concentrators and can readily be switched between an open highly light transmissive state and a closed highly thermally insulating state. This variable light valve makes the transition between high thermal insulation and efficient light transmittance practical and may be useful in plant growth environments to provide both adequate sunlight illumination and thermal insulation as needed. We have measured light transmittance values exceeding 80% for the light valve design and achieved thermal insulation values substantially exceeding those of traditional energy efficient windows. The light valve system presented in this paper represents a potential solution for greenhouse food production in locations where greenhouses are not feasible economically due to high heating cost.

Causes of Variability in the Effects of Vegetative Ash on Post-Fire Runoff and Erosion

NASA Astrophysics Data System (ADS)

Balfour, V.; Woods, S.

2008-12-01

Vegetative ash formed during forest wildfires has varying effects on post-fire runoff and erosion. In some cases the ash layer reduces runoff and erosion by storing rainfall and by protecting the soil surface from surface sealing and rainsplash detachment. In other cases, the ash layer increases runoff and erosion by forming a surface crust, clogging soil pores, and providing a ready source of highly erodible fine material. Since only a handful of studies have measured the hydrogeomorphic effect of ash, it is unclear whether the observed variability in its effect reflects initial spatial variability in the ash properties due to factors such as fuel type and fire severity, or differences that develop over time due to compaction and erosion or exposure of the ash to rainfall and air. The goal of our research was to determine if the observed differences in the effect of ash on runoff and erosion are due to: 1) variability in initial ash hydrologic properties due to differences in combustion temperature and fuel type, or 2) variability in ash hydrologic properties caused by mineralogical phase changes that develop after the ash is exposed to water. We created ash in the laboratory using wood and needles of Lodgepole pine (Pinus contorta), Ponderosa pine (Pinus Ponderosa) and Douglas fir (Pseudotsuga menziesii) and at 100° C temperature increments from 300 to 900° C. A subsample of ash from each fuel type / temperature combination was saturated, left undisturbed for 24 hours and then oven dried at 104° C. Dry and wetted ash samples were characterized in terms of: structure (using a scanning electron microscope), carbon content, mineralogy (using X-ray diffraction), porosity, water retention properties and hydraulic conductivity. Ash produced at the higher combustion temperatures from all three fuel types contained lime (CaO), which on wetting was transformed to portlandite (Ca(OH)2) and calcite (CaCO3). This mineralogical transformation resulted in irreversible hardening and crusting of the ash, and hardened ash had a significantly lower hydraulic conductivity than unhardened ash. Ash produced by high severity fires may undergo this same hardening and crusting process after it is wetted by rainfall whereas ash produced by lower severity fires will not, and this may explain in part the contrasting hydrogeomorphic effects of ash that have been reported in the literature.

Investigation of clinical pharmacokinetic variability of an opioid antagonist through physiologically based absorption modeling.

PubMed

Ding, Xuan; He, Minxia; Kulkarni, Rajesh; Patel, Nita; Zhang, Xiaoyu

2013-08-01

Identifying the source of inter- and/or intrasubject variability in pharmacokinetics (PK) provides fundamental information in understanding the pharmacokinetics-pharmacodynamics relationship of a drug and project its efficacy and safety in clinical populations. This identification process can be challenging given that a large number of potential causes could lead to PK variability. Here we present an integrated approach of physiologically based absorption modeling to investigate the root cause of unexpectedly high PK variability of a Phase I clinical trial drug. LY2196044 exhibited high intersubject variability in the absorption phase of plasma concentration-time profiles in humans. This could not be explained by in vitro measurements of drug properties and excellent bioavailability with low variability observed in preclinical species. GastroPlus™ modeling suggested that the compound's optimal solubility and permeability characteristics would enable rapid and complete absorption in preclinical species and in humans. However, simulations of human plasma concentration-time profiles indicated that despite sufficient solubility and rapid dissolution of LY2196044 in humans, permeability and/or transit in the gastrointestinal (GI) tract may have been negatively affected. It was concluded that clinical PK variability was potentially due to the drug's antagonism on opioid receptors that affected its transit and absorption in the GI tract. Copyright © 2013 Wiley Periodicals, Inc.

Ultra-high-speed variable focus optics for novel applications in advanced imaging

NASA Astrophysics Data System (ADS)

Kang, S.; Dotsenko, E.; Amrhein, D.; Theriault, C.; Arnold, C. B.

2018-02-01

With the advancement of ultra-fast manufacturing technologies, high speed imaging with high 3D resolution has become increasingly important. Here we show the use of an ultra-high-speed variable focus optical element, the TAG Lens, to enable new ways to acquire 3D information from an object. The TAG Lens uses sound to adjust the index of refraction profile in a liquid and thereby can achieve focal scanning rates greater than 100 kHz. When combined with a high-speed pulsed LED and a high-speed camera, we can exploit this phenomenon to achieve high-resolution imaging through large depths. By combining the image acquisition with digital image processing, we can extract relevant parameters such as tilt and angle information from objects in the image. Due to the high speeds at which images can be collected and processed, we believe this technique can be used as an efficient method of industrial inspection and metrology for high throughput applications.

Variability of residual stresses and superposition effect in multipass grinding of high-carbon high-chromium steel

NASA Astrophysics Data System (ADS)

Karabelchtchikova, Olga; Rivero, Iris V.

2005-02-01

The distribution of residual stresses (RS) and surface integrity generated in heat treatment and subsequent multipass grinding was investigated in this experimental study to examine the source of variability and the nature of the interactions of the experimental factors. A nested experimental design was implemented to (a) compare the sources of the RS variability, (b) to examine RS distribution and tensile peak location due to experimental factors, and (c) to analyze the superposition relationship in the RS distribution due to multipass grinding technique. To characterize the material responses, several techniques were used, including microstructural analysis, hardness-toughness and roughness examinations, and retained austenite and RS measurements using x-ray diffraction. The causality of the RS was explained through the strong correlation of the surface integrity characteristics and RS patterns. The main sources of variation were the depth of the RS distribution and the multipass grinding technique. The grinding effect on the RS was statistically significant; however, it was mostly predetermined by the preexisting RS induced in heat treatment. Regardless of the preceding treatments, the effect of the multipass grinding technique exhibited similar RS patterns, which suggests the existence of the superposition relationship and orthogonal memory between the passes of the grinding operation.

Variable Selection through Correlation Sifting

NASA Astrophysics Data System (ADS)

Huang, Jim C.; Jojic, Nebojsa

Many applications of computational biology require a variable selection procedure to sift through a large number of input variables and select some smaller number that influence a target variable of interest. For example, in virology, only some small number of viral protein fragments influence the nature of the immune response during viral infection. Due to the large number of variables to be considered, a brute-force search for the subset of variables is in general intractable. To approximate this, methods based on ℓ1-regularized linear regression have been proposed and have been found to be particularly successful. It is well understood however that such methods fail to choose the correct subset of variables if these are highly correlated with other "decoy" variables. We present a method for sifting through sets of highly correlated variables which leads to higher accuracy in selecting the correct variables. The main innovation is a filtering step that reduces correlations among variables to be selected, making the ℓ1-regularization effective for datasets on which many methods for variable selection fail. The filtering step changes both the values of the predictor variables and output values by projections onto components obtained through a computationally-inexpensive principal components analysis. In this paper we demonstrate the usefulness of our method on synthetic datasets and on novel applications in virology. These include HIV viral load analysis based on patients' HIV sequences and immune types, as well as the analysis of seasonal variation in influenza death rates based on the regions of the influenza genome that undergo diversifying selection in the previous season.

Topographic heterogeneity and temperature amplitude explain species richness patterns of birds in the Qinghai-Tibetan Plateau.

PubMed

Zhang, Chunlan; Quan, Qing; Wu, Yongjie; Chen, Youhua; He, Peng; Qu, Yanhua; Lei, Fumin

2017-04-01

Large-scale patterns of species richness have gained much attention in recent years; however, the factors that drive high species richness are still controversial in local regions, especially in highly diversified montane regions. The Qinghai-Tibetan Plateau (QTP) and the surrounding mountains are biodiversity hot spots due to a high number of endemic montane species. Here, we explored the factors underlying this high level of diversity by studying the relationship between species richness and environmental variables. The richness patterns of 758 resident bird species were summarized at the scale of 1°×1° grid cell at different taxonomic levels (order, family, genus, and species) and in different taxonomic groups (Passeriformes, Galliformes, Falconiformes, and Columbiformes). These richness patterns were subsequently analyzed against habitat heterogeneity (topographical heterogeneity and land cover), temperature amplitude (annual temperature, annual precipitation, precipitation seasonality, and temperature seasonality) and a vegetation index (net primary productivity). Our results showed that the highest richness was found in the southeastern part of the QTP, the eastern Himalayas. The lowest richness was observed in the central plateau of the QTP. Topographical heterogeneity and temperature amplitude are the primary factors that explain overall patterns of species richness in the QTP, although the specific effect of each environmental variable varies between the different taxonomic groups depending on their own evolutionary histories and ecological requirements. High species richness in the southeastern QTP is mostly due to highly diversified habitat types and temperature zones along elevation gradients, whereas the low species richness in the central plateau of the QTP may be due to environmental and energetic constraints, as the central plateau is harsh environment.

Day-to-day variability of midlatitude ionospheric currents due to magnetospheric and lower atmospheric forcing

NASA Astrophysics Data System (ADS)

Yamazaki, Y.; Häusler, K.; Wild, J. A.

2016-07-01

As known from previous studies on the solar quiet (Sq) variation of the geomagnetic field, the strength and pattern of ionospheric dynamo currents change significantly from day to day. The present study investigates the relative importance of two sources that contribute to the day-to-day variability of the ionospheric currents at middle and low latitudes. One is high-latitude electric fields that are caused by magnetospheric convection, and the other is atmospheric waves from the lower atmosphere. Global ionospheric current systems, commonly known as Sq current systems, are simulated using the National Center for Atmospheric Research thermosphere-ionosphere-mesosphere-electrodynamics general circulation model. Simulations are run for 1-30 April 2010 with a constant solar energy input but with various combinations of high-latitude forcing and lower atmospheric forcing. The model well reproduces geomagnetic perturbations on the ground, when both forcings are taken into account. The contribution of high-latitude forcing to the total Sq current intensity (Jtotal) is generally smaller than the contribution of wave forcing from below 30 km, except during active periods (Kp≥4), when Jtotal is enhanced due to the leakage of high-latitude electric fields to lower latitudes. It is found that the penetration electric field drives ionospheric currents at middle and low latitudes not only on the dayside but also on the nightside, which has an appreciable effect on the Dst index. It is also found that quiet time day-to-day variability in Jtotal is dominated by symmetric-mode migrating diurnal and semidiurnal tidal winds at 45-60° latitude at ˜110 km.

TopoSCALE v.1.0: downscaling gridded climate data in complex terrain

NASA Astrophysics Data System (ADS)

Fiddes, J.; Gruber, S.

2014-02-01

Simulation of land surface processes is problematic in heterogeneous terrain due to the the high resolution required of model grids to capture strong lateral variability caused by, for example, topography, and the lack of accurate meteorological forcing data at the site or scale it is required. Gridded data products produced by atmospheric models can fill this gap, however, often not at an appropriate spatial resolution to drive land-surface simulations. In this study we describe a method that uses the well-resolved description of the atmospheric column provided by climate models, together with high-resolution digital elevation models (DEMs), to downscale coarse-grid climate variables to a fine-scale subgrid. The main aim of this approach is to provide high-resolution driving data for a land-surface model (LSM). The method makes use of an interpolation of pressure-level data according to topographic height of the subgrid. An elevation and topography correction is used to downscale short-wave radiation. Long-wave radiation is downscaled by deriving a cloud-component of all-sky emissivity at grid level and using downscaled temperature and relative humidity fields to describe variability with elevation. Precipitation is downscaled with a simple non-linear lapse and optionally disaggregated using a climatology approach. We test the method in comparison with unscaled grid-level data and a set of reference methods, against a large evaluation dataset (up to 210 stations per variable) in the Swiss Alps. We demonstrate that the method can be used to derive meteorological inputs in complex terrain, with most significant improvements (with respect to reference methods) seen in variables derived from pressure levels: air temperature, relative humidity, wind speed and incoming long-wave radiation. This method may be of use in improving inputs to numerical simulations in heterogeneous and/or remote terrain, especially when statistical methods are not possible, due to lack of observations (i.e. remote areas or future periods).

Excised leaf method for high volume evaluation of sorghum germplasm for resistance against Colletotrichum sublineolum

USDA-ARS?s Scientific Manuscript database

Foliar phase of anthracnose, caused by Colletotrichum sublineolum is the most important leaf disease of sorghum. Due to the hyper-variable nature of the fungus, continuous evaluation of sorghum germplasm to identify new sources of resistance is imperative. Field and greenhouse evaluations for anth...

The Politics of Teaching Evolution, Science Education Standards, and "Being" a Creationist

ERIC Educational Resources Information Center

Long, David E.

2012-01-01

This paper analyzes recent research conclusions regarding biology teacher attitudes toward evolution, and the variable implementation of evolution in the high schools nationwide. Berkman and Plutzer (2010. "Evolution, creationism, and the battle to control America's classrooms." New York: Cambridge University Press) conclude that due to a large…

Evaluation of common bean lines for adaptation to high temperatures in Honduras

USDA-ARS?s Scientific Manuscript database

As in other regions worldwide, common bean (Phaseolus vulgaris L.) production in Central America and the Caribbean (CA/C) region is threatened by effects of climate change including increasing temperatures and drought due to variable rainfall patterns. One of the main alternatives for increasing ada...

REGIONAL ASSESSMENT OF METHANE EMISSION RATES FROM RESERVOIRS IN THE MIDWESTERN UNITED STATES

EPA Science Inventory

Reservoirs are a globally significant source of methane (CH4) to the atmosphere, but regional and global emission estimates are poorly constrained due to high variability in emission rates among reservoirs and a lack of measurements in some areas geographic areas. Methane emissi...

Development of genomic microsatellites in Gleditsia triacanthos (Fabaceae) using illumina sequencing

Treesearch

Sandra A. Owusu; Margaret Staton; Tara N. Jennings; Scott Schlarbaum; Mark V. Coggeshall; Jeanne Romero-Severson; John E. Carlson; Oliver Gailing

2013-01-01

Premise of the study: Fourteen genomic microsatellite markers were developed and characterized in honey locust, Gleditsia triacanthos, using Illumina sequencing. Due to their high variability, these markers can be applied in analyses of genetic diversity and structure, and in mating system and gene flow studies.

Climate Prediction Center - Seasonal Outlook

Science.gov Websites

SEASONAL CLIMATE VARIABILITY, INCLUDING ENSO, SOIL MOISTURE, AND VARIOUS STATE-OF-THE-ART DYNAMICAL MODEL ACROSS PARTS OF THE EAST-CENTRAL CONUS CENTERED ON THE MISSISSIPPI RIVER. THIS IS DUE TO VERY HIGH SOIL TRENDS, NEGATIVE SOIL MOISTURE ANOMALIES, LAGGED ENSO REGRESSIONS, AND DYNAMICAL MODEL GUIDANCE ARE ALL

Development of design guidelines for proper selection of graded aggregate base in Maryland state highways : [research summary].

DOT National Transportation Integrated Search

2015-01-01

Millions of tons of graded aggregate base (GAB) materials are used in construction of : highway base layers in Maryland due to their satisfactory mechanical properties. The : fines content of a GAB material is highly variable and is often related to ...

Comparison of Two Grid Refinement Approaches for High Resolution Regional Climate Modeling: MPAS vs WRF

NASA Astrophysics Data System (ADS)

Leung, L.; Hagos, S. M.; Rauscher, S.; Ringler, T.

2012-12-01

This study compares two grid refinement approaches using global variable resolution model and nesting for high-resolution regional climate modeling. The global variable resolution model, Model for Prediction Across Scales (MPAS), and the limited area model, Weather Research and Forecasting (WRF) model, are compared in an idealized aqua-planet context with a focus on the spatial and temporal characteristics of tropical precipitation simulated by the models using the same physics package from the Community Atmosphere Model (CAM4). For MPAS, simulations have been performed with a quasi-uniform resolution global domain at coarse (1 degree) and high (0.25 degree) resolution, and a variable resolution domain with a high-resolution region at 0.25 degree configured inside a coarse resolution global domain at 1 degree resolution. Similarly, WRF has been configured to run on a coarse (1 degree) and high (0.25 degree) resolution tropical channel domain as well as a nested domain with a high-resolution region at 0.25 degree nested two-way inside the coarse resolution (1 degree) tropical channel. The variable resolution or nested simulations are compared against the high-resolution simulations that serve as virtual reality. Both MPAS and WRF simulate 20-day Kelvin waves propagating through the high-resolution domains fairly unaffected by the change in resolution. In addition, both models respond to increased resolution with enhanced precipitation. Grid refinement induces zonal asymmetry in precipitation (heating), accompanied by zonal anomalous Walker like circulations and standing Rossby wave signals. However, there are important differences between the anomalous patterns in MPAS and WRF due to differences in the grid refinement approaches and sensitivity of model physics to grid resolution. This study highlights the need for "scale aware" parameterizations in variable resolution and nested regional models.

Transdermal scopolamine in the prevention of motion sickness - Evaluation of the time course of efficacy

NASA Technical Reports Server (NTRS)

Homick, J. L.; Reschke, M. F.; Degioanni, J.; Cintron-Trevino, N. M.; Kohl, R. L.

1983-01-01

This study evaluated the time course of efficacy of transdermal scopolamine in the prevention of motion sickness induced by exposure to coriolis stimulation in a rotating chair. We measured levels of efficacy, quantified side effects and symptoms, and determined inter- and intra-subject variability following use of transdermal scopolamine. The response to transdermal scopolamine was highly variable, although overall we recorded a 40 percent improvement in test scores 16-72 h after application of the transdermal system. This variability could not be explained solely by the levels of scopolamine present in the blood. The improvement was not due to the artifactual repression by scopolamine of selected symptoms of motion sickness. An unexpectedly high incidence of side effects was reported. It was concluded that the therapeutic use of transdermal scopolamine be evaluated individually and that individuals be cautioned that subsequent usage may not always be effective.

An oilspill trajectory analysis model with a variable wind deflection angle

USGS Publications Warehouse

Samuels, W.B.; Huang, N.E.; Amstutz, D.E.

1982-01-01

The oilspill trajectory movement algorithm consists of a vector sum of the surface drift component due to wind and the surface current component. In the U.S. Geological Survey oilspill trajectory analysis model, the surface drift component is assumed to be 3.5% of the wind speed and is rotated 20 degrees clockwise to account for Coriolis effects in the Northern Hemisphere. Field and laboratory data suggest, however, that the deflection angle of the surface drift current can be highly variable. An empirical formula, based on field observations and theoretical arguments relating wind speed to deflection angle, was used to calculate a new deflection angle at each time step in the model. Comparisons of oilspill contact probabilities to coastal areas calculated for constant and variable deflection angles showed that the model is insensitive to this changing angle at low wind speeds. At high wind speeds, some statistically significant differences in contact probabilities did appear. ?? 1982.

Systems, methods, and software for determining spatially variable distributions of the dielectric properties of a heterogeneous material

DOE Office of Scientific and Technical Information (OSTI.GOV)

Farrington, Stephen P.

Systems, methods, and software for measuring the spatially variable relative dielectric permittivity of materials along a linear or otherwise configured sensor element, and more specifically the spatial variability of soil moisture in one dimension as inferred from the dielectric profile of the soil matrix surrounding a linear sensor element. Various methods provided herein combine advances in the processing of time domain reflectometry data with innovations in physical sensing apparatuses. These advancements enable high temporal (and thus spatial) resolution of electrical reflectance continuously along an insulated waveguide that is permanently emplaced in contact with adjacent soils. The spatially resolved reflectance ismore » directly related to impedance changes along the waveguide that are dominated by electrical permittivity contrast due to variations in soil moisture. Various methods described herein are thus able to monitor soil moisture in profile with high spatial resolution.« less

Low-Dimensional Statistics of Anatomical Variability via Compact Representation of Image Deformations.

PubMed

Zhang, Miaomiao; Wells, William M; Golland, Polina

2016-10-01

Using image-based descriptors to investigate clinical hypotheses and therapeutic implications is challenging due to the notorious "curse of dimensionality" coupled with a small sample size. In this paper, we present a low-dimensional analysis of anatomical shape variability in the space of diffeomorphisms and demonstrate its benefits for clinical studies. To combat the high dimensionality of the deformation descriptors, we develop a probabilistic model of principal geodesic analysis in a bandlimited low-dimensional space that still captures the underlying variability of image data. We demonstrate the performance of our model on a set of 3D brain MRI scans from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database. Our model yields a more compact representation of group variation at substantially lower computational cost than models based on the high-dimensional state-of-the-art approaches such as tangent space PCA (TPCA) and probabilistic principal geodesic analysis (PPGA).

Variability at the edge: highly accreting objects in Taurus

NASA Astrophysics Data System (ADS)

Abraham, Peter; Kospal, Agnes; Szabo, Robert

2017-04-01

In Kepler K2, Campaign 13, we will obtain 80-days-long optical light curves of seven highly accreting T Tauri stars in the benchmark Taurus star forming region. Here we propose to monitor our sample simultaneously with Kepler and Spitzer, to be able to separate variability patterns related to different physical processes. Monitoring our targets with Spitzer during the final 11 days of the K2 campaign, we will clean the light curves from non-accretion effects (rotating stellar spots, dips due to passing dust structures), and construct, for the first time, a variability curve which reflects the time-dependent accretion only. We will then study and understand how time-dependent mass accretion affects the density and temperature structure of the protoplanetary disk, which sets the initial conditions for planet formation. The proposed work cannot be done without the unparalleled precision of Kepler and Spitzer. This unique and one-time opportunity motivated our DDT proposal.

Length and sequence variability in mitochondrial control region of the milkfish, Chanos chanos.

PubMed

Ravago, Rachel G; Monje, Virginia D; Juinio-Meñez, Marie Antonette

2002-01-01

Extensive length variability was observed in the mitochondrial control region of the milkfish, Chanos chanos. The nucleotide sequence of the control region and flanking regions was determined. Length variability and heteroplasmy was due to the presence of varying numbers of a 41-bp tandemly repeated sequence and a 48-bp insertion/deletion (indel). The structure and organization of the milkfish control region is similar to that of other teleost fish and vertebrates. However, extensive variation in the copy number of tandem repeats (4-20 copies) and the presence of a relatively large (48-bp) indel, are apparently uncommon in teleost fish control region sequences reported to date. High sequence variability of control region peripheral domains indicates the potential utility of selected regions as markers for population-level studies.

Assessment of chlorophyll variability along the northwestern coast of Iberian Peninsula

NASA Astrophysics Data System (ADS)

Picado, A.; Alvarez, I.; Vaz, N.; Varela, R.; Gomez-Gesteira, M.; Dias, J. M.

2014-10-01

The northwestern coast of the Iberian Peninsula is characterized by a high primary production mainly supported by coastal upwelling, creating an extraordinary commercial interest for fisheries and aquaculture. Considering chlorophyll-a (Chl-a) as an indicator of primary production, its spatio-temporal variability was researched in this study in the surface water of this upwelling region from 1998 to 2007. Satellite derived Chl-a, Sea Surface Temperature (SST) and Ekman transport data as well as the inflow of the main rivers discharging into the study area were used to investigate the origin of the Chl-a concentration. Empirical Orthogonal Function (EOF) analysis of weekly Chl-a images was performed, as well as correlation analysis between Chl-a concentration, Ekman transport and river discharge. EOF results suggest that the highest Chl-a concentration occurs near the coast up to 60 km offshore. The interannual variability of Chl-a, SST and Ekman transport was also studied considering summer and winter months. Generally, 2005, 2006 and 2007 were the most productive years during the summer months with high Chl-a concentrations along the coast associated to the strong upwelling conditions observed. Otherwise, 1998 seemed to be the most productive year during winter. The absence of upwelling favorable conditions together with localized low SST and considerable discharges, suggests that the high Chl-a concentrations observed during this period are mainly due to the entrance of nutrients through river runoff. However, in winter, high concentrations of colored dissolved organic matter (CDOM), associated with river runoff, are present in the ocean surface, leading to an erroneous strong signal of the satellite. During winter correlations of 0.58 and 0.49 were found between Chl-a concentration and Douro and Minho discharges, respectively, evidencing that high Chl-a concentration was related with river runoff. Otherwise, during summer, Chl-a and Ekman transport exhibited a correlation of - 0.38 indicating that high Chl-a is associated to upwelling events. In summary, it was found that the spatio-temporal variability of Chl-a along the northwestern coast of Iberian Peninsula exhibited the clear influence of upwelling events during summer. Conversely, the variability during winter was mainly due to entrance of nutrients through the rivers discharge which flow into the area.

Multiband VLBI Observations of CTA102

NASA Technical Reports Server (NTRS)

Rantakyro, F. T.; Baath, L. B.; Dallacasa, D.; Jones, D. L.; Wehrle, A. E.

1995-01-01

The source CTA102, known to exhibit low frequency variability, has been observed at six epochs (three at lambda 32 cm, two at lambda 18 cm, and one at lambda l.3 cm) with intercontinental VLBI arrays. On the basis of the changes observed in the structure, we believe that the flux density variations at these wavelengths are due to intrinsic processes and not due to interstellar scintillation. This source exhibits behaviour suggestive of being expanding with a very high apparent transverse velocity.

Closed treatment of unilateral mandibular condyle fractures in adults: a systematic review.

PubMed

Rozeboom, A V J; Dubois, L; Bos, R R M; Spijker, R; de Lange, J

2017-04-01

Of all mandibular fractures, 25-35% are condylar. Many studies have focused on whether to treat such fractures via open or closed modalities. A uniform protocol for closed treatment is lacking, but such a protocol could ensure good clinical practice. The aims of this systematic review were to provide an overview of the published studies exclusively pertaining to closed treatment and to summarize the existing modalities for closed treatment and their clinical outcomes. Sixteen studies were selected for detailed analysis. The treatments given were highly variable, ranging from doing nothing to applying maxillomandibular fixation with stainless steel wires. The results of the different studies and the treatment modalities used were difficult to interpret; however no clear differences in the outcome measures were seen between the treatment modalities applied. Complications encountered after closed treatment included malocclusion, limited mouth opening, reduced range of motion, and persistent pain. Due to the heterogeneity between groups, high loss-to-follow-up, poor descriptions of the treatments given, and variability in outcome measurement methods, no clear associations between adverse outcomes and the treatments applied could be determined. This review suggests that due to the high level of methodological variability in the relevant studies published to date, there are currently no uniform standards for the closed treatment of condylar fractures that can be expected to yield good clinical results. The establishment of such standards could potentially improve treatment outcomes. Copyright © 2016 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

State estimation and prediction using clustered particle filters.

PubMed

Lee, Yoonsang; Majda, Andrew J

2016-12-20

Particle filtering is an essential tool to improve uncertain model predictions by incorporating noisy observational data from complex systems including non-Gaussian features. A class of particle filters, clustered particle filters, is introduced for high-dimensional nonlinear systems, which uses relatively few particles compared with the standard particle filter. The clustered particle filter captures non-Gaussian features of the true signal, which are typical in complex nonlinear dynamical systems such as geophysical systems. The method is also robust in the difficult regime of high-quality sparse and infrequent observations. The key features of the clustered particle filtering are coarse-grained localization through the clustering of the state variables and particle adjustment to stabilize the method; each observation affects only neighbor state variables through clustering and particles are adjusted to prevent particle collapse due to high-quality observations. The clustered particle filter is tested for the 40-dimensional Lorenz 96 model with several dynamical regimes including strongly non-Gaussian statistics. The clustered particle filter shows robust skill in both achieving accurate filter results and capturing non-Gaussian statistics of the true signal. It is further extended to multiscale data assimilation, which provides the large-scale estimation by combining a cheap reduced-order forecast model and mixed observations of the large- and small-scale variables. This approach enables the use of a larger number of particles due to the computational savings in the forecast model. The multiscale clustered particle filter is tested for one-dimensional dispersive wave turbulence using a forecast model with model errors.

Highly variable Pliocene sea surface conditions in the Norwegian Sea

NASA Astrophysics Data System (ADS)

Bachem, Paul E.; Risebrobakken, Bjørg; De Schepper, Stijn; McClymont, Erin L.

2017-09-01

The Pliocene was a time of global warmth with small sporadic glaciations, which transitioned towards the larger-scale Pleistocene glacial-interglacial variability. Here, we present high-resolution records of sea surface temperature (SST) and ice-rafted debris (IRD) in the Norwegian Sea from 5.32 to 3.14 Ma, providing evidence that the Pliocene surface conditions of the Norwegian Sea underwent a series of transitions in response to orbital forcing and gateway changes. Average SSTs are 2 °C above the regional Holocene mean, with notable variability on millennial to orbital timescales. Both gradual changes and threshold effects are proposed for the progression of regional climate towards the Late Pliocene intensification of Northern Hemisphere glaciation. Cooling from 4.5 to 4.3 Ma may be linked to the onset of poleward flow through the Bering Strait. This cooling was further intensified by a period of cool summers due to weak obliquity forcing. A 7 °C warming of the Norwegian Sea at 4.0 Ma suggests a major increase in northward heat transport from the North Atlantic, leading to an enhanced zonal SST gradient in the Nordic Seas, which may be linked to the expansion of sea ice in the Arctic and Nordic Seas. A warm Norwegian Sea and enhanced zonal temperature gradient between 4.0 and 3.6 Ma may have been a priming factor for increased glaciation around the Nordic Seas due to enhanced evaporation and precipitation at high northern latitudes.

State estimation and prediction using clustered particle filters

PubMed Central

Lee, Yoonsang; Majda, Andrew J.

2016-01-01

Particle filtering is an essential tool to improve uncertain model predictions by incorporating noisy observational data from complex systems including non-Gaussian features. A class of particle filters, clustered particle filters, is introduced for high-dimensional nonlinear systems, which uses relatively few particles compared with the standard particle filter. The clustered particle filter captures non-Gaussian features of the true signal, which are typical in complex nonlinear dynamical systems such as geophysical systems. The method is also robust in the difficult regime of high-quality sparse and infrequent observations. The key features of the clustered particle filtering are coarse-grained localization through the clustering of the state variables and particle adjustment to stabilize the method; each observation affects only neighbor state variables through clustering and particles are adjusted to prevent particle collapse due to high-quality observations. The clustered particle filter is tested for the 40-dimensional Lorenz 96 model with several dynamical regimes including strongly non-Gaussian statistics. The clustered particle filter shows robust skill in both achieving accurate filter results and capturing non-Gaussian statistics of the true signal. It is further extended to multiscale data assimilation, which provides the large-scale estimation by combining a cheap reduced-order forecast model and mixed observations of the large- and small-scale variables. This approach enables the use of a larger number of particles due to the computational savings in the forecast model. The multiscale clustered particle filter is tested for one-dimensional dispersive wave turbulence using a forecast model with model errors. PMID:27930332

North Atlantic Origin of Interdecadal variability of Siberian High

NASA Astrophysics Data System (ADS)

Kim, Seon-Hwa; Sung, Mi-Kyung; Kim, Baek-Min

2017-04-01

We suggest that the changes in the mean atmospheric circulation structure in the North Atlantic Ocean upstream region of Eurasian continent play an important role in the interdecadal variability of Siberian High (SH) through the modulation of Ural blocking frequency. Previous studies suggested that the interdecadal variability of SH is partly explained by the Arctic Oscillation. However, in this study, we emphasize the role of 'Warm Arctic and Cold Eurasia (WACE)', which is the second mode of winter surface air temperature variability over Eurasia. We show that the correlation between SH and WACE is high in general compared to that between SH and AO. However, the correlation between SH and WACE does not always exhibit high constant value. It shows a distinctive interdecadal fluctuation in the correlation. We found that this fluctuation in the correlation is due to the interdecadal fluctuation of the continental trough over the North Atlantic and the resultant strengthening of in-situ atmospheric baroclinicity. This accompanies changes in the transient vorticity flux divergence which leads to the downstream wave development and anomalous anticyclonic flow near Ural region. Obviously, the existence of anticyclonic flow over Ural region helps more frequent occurrence of Ural blocking and it is shown that this condition favors positive WACE event, which links to an intensified SH.

A critical assessment of in-flight particle state during plasma spraying of YSZ and its implications on coating properties and process reliability

NASA Astrophysics Data System (ADS)

Srinivasan, Vasudevan

Air plasma spray is inherently complex due to the deviation from equilibrium conditions, three dimensional nature, multitude of interrelated (controllable) parameters and (uncontrollable) variables involved, and stochastic variability at different stages. The resultant coatings are complex due to the layered high defect density microstructure. Despite the widespread use and commercial success for decades in earthmoving, automotive, aerospace and power generation industries, plasma spray has not been completely understood and prime reliance for critical applications such as thermal barrier coatings on gas turbines are yet to be accomplished. This dissertation is aimed at understanding the in-flight particle state of the plasma spray process towards designing coatings and achieving coating reliability with the aid of noncontact in-flight particle and spray stream sensors. Key issues such as the phenomena of optimum particle injection and the definition of spray stream using particle state are investigated. Few strategies to modify the microstructure and properties of Yttria Stabilized Zirconia coatings are examined systematically using the framework of process maps. An approach to design process window based on design relevant coating properties is presented. Options to control the process for enhanced reproducibility and reliability are examined and the resultant variability is evaluated systematically at the different stages in the process. The 3D variability due to the difference in plasma characteristics has been critically examined by investigating splats collected from the entire spray footprint.

Comparison of Nondestructive Testing Methods for Evaluating No. 2 Southern Pine Lumber: Part A, Modulus of Elasticity

Treesearch

B.Z. Yang; R.D. Seale; R. Shmulsky; J. Dahlen; Xiping Wang

2015-01-01

Modulus of elasticity (MOE, or E) is one of the main quality indicators in structural lumber stress grading systems. Due to a relatively high amount of variability in contemporary sawn lumber, it is important that nondestructive evaluation technology be utilized to better discern high-E-value pieces from low-E-value pieces. The research described in this study is from...

Analysis of the labor productivity of enterprises via quantile regression

NASA Astrophysics Data System (ADS)

Türkan, Semra

2017-07-01

In this study, we have analyzed the factors that affect the performance of Turkey's Top 500 Industrial Enterprises using quantile regression. The variable about labor productivity of enterprises is considered as dependent variable, the variableabout assets is considered as independent variable. The distribution of labor productivity of enterprises is right-skewed. If the dependent distribution is skewed, linear regression could not catch important aspects of the relationships between the dependent variable and its predictors due to modeling only the conditional mean. Hence, the quantile regression, which allows modelingany quantilesof the dependent distribution, including the median,appears to be useful. It examines whether relationships between dependent and independent variables are different for low, medium, and high percentiles. As a result of analyzing data, the effect of total assets is relatively constant over the entire distribution, except the upper tail. It hasa moderately stronger effect in the upper tail.

The variable flavor number scheme at next-to-leading order

NASA Astrophysics Data System (ADS)

Blümlein, J.; De Freitas, A.; Schneider, C.; Schönwald, K.

2018-07-01

We present the matching relations of the variable flavor number scheme at next-to-leading order, which are of importance to define heavy quark partonic distributions for the use at high energy colliders such as Tevatron and the LHC. The consideration of the two-mass effects due to both charm and bottom quarks, having rather similar masses, are important. These effects have not been considered in previous investigations. Numerical results are presented for a wide range of scales. We also present the corresponding contributions to the structure function F2 (x ,Q2).

Biogeochemical modelling of dissolved oxygen in a changing ocean.

PubMed

Andrews, Oliver; Buitenhuis, Erik; Le Quéré, Corinne; Suntharalingam, Parvadha

2017-09-13

Secular decreases in dissolved oxygen concentration have been observed within the tropical oxygen minimum zones (OMZs) and at mid- to high latitudes over the last approximately 50 years. Earth system model projections indicate that a reduction in the oxygen inventory of the global ocean, termed ocean deoxygenation, is a likely consequence of on-going anthropogenic warming. Current models are, however, unable to consistently reproduce the observed trends and variability of recent decades, particularly within the established tropical OMZs. Here, we conduct a series of targeted hindcast model simulations using a state-of-the-art global ocean biogeochemistry model in order to explore and review biases in model distributions of oceanic oxygen. We show that the largest magnitude of uncertainty is entrained into ocean oxygen response patterns due to model parametrization of p CO 2 -sensitive C : N ratios in carbon fixation and imposed atmospheric forcing data. Inclusion of a p CO 2 -sensitive C : N ratio drives historical oxygen depletion within the ocean interior due to increased organic carbon export and subsequent remineralization. Atmospheric forcing is shown to influence simulated interannual variability in ocean oxygen, particularly due to differences in imposed variability of wind stress and heat fluxes.This article is part of the themed issue 'Ocean ventilation and deoxygenation in a warming world'. © 2017 The Author(s).

Biogeochemical modelling of dissolved oxygen in a changing ocean

NASA Astrophysics Data System (ADS)

Andrews, Oliver; Buitenhuis, Erik; Le Quéré, Corinne; Suntharalingam, Parvadha

2017-08-01

Secular decreases in dissolved oxygen concentration have been observed within the tropical oxygen minimum zones (OMZs) and at mid- to high latitudes over the last approximately 50 years. Earth system model projections indicate that a reduction in the oxygen inventory of the global ocean, termed ocean deoxygenation, is a likely consequence of on-going anthropogenic warming. Current models are, however, unable to consistently reproduce the observed trends and variability of recent decades, particularly within the established tropical OMZs. Here, we conduct a series of targeted hindcast model simulations using a state-of-the-art global ocean biogeochemistry model in order to explore and review biases in model distributions of oceanic oxygen. We show that the largest magnitude of uncertainty is entrained into ocean oxygen response patterns due to model parametrization of pCO2-sensitive C : N ratios in carbon fixation and imposed atmospheric forcing data. Inclusion of a pCO2-sensitive C : N ratio drives historical oxygen depletion within the ocean interior due to increased organic carbon export and subsequent remineralization. Atmospheric forcing is shown to influence simulated interannual variability in ocean oxygen, particularly due to differences in imposed variability of wind stress and heat fluxes. This article is part of the themed issue 'Ocean ventilation and deoxygenation in a warming world'.

Whole genome sequencing of the monomorphic pathogen Mycobacterium bovis reveals local differentiation of cattle clinical isolates.

PubMed

Lasserre, Moira; Fresia, Pablo; Greif, Gonzalo; Iraola, Gregorio; Castro-Ramos, Miguel; Juambeltz, Arturo; Nuñez, Álvaro; Naya, Hugo; Robello, Carlos; Berná, Luisa

2018-01-02

Bovine tuberculosis (bTB) poses serious risks to animal welfare and economy, as well as to public health as a zoonosis. Its etiological agent, Mycobacterium bovis, belongs to the Mycobacterium tuberculosis complex (MTBC), a group of genetically monomorphic organisms featured by a remarkably high overall nucleotide identity (99.9%). Indeed, this characteristic is of major concern for correct typing and determination of strain-specific traits based on sequence diversity. Due to its historical economic dependence on cattle production, Uruguay is deeply affected by the prevailing incidence of Mycobacterium bovis. With the world's highest number of cattle per human, and its intensive cattle production, Uruguay represents a particularly suited setting to evaluate genomic variability among isolates, and the diversity traits associated to this pathogen. We compared 186 genomes from MTBC strains isolated worldwide, and found a highly structured population in M. bovis. The analysis of 23 new M. bovis genomes, belonging to strains isolated in Uruguay evidenced three groups present in the country. Despite presenting an expected highly conserved genomic structure and sequence, these strains segregate into a clustered manner within the worldwide phylogeny. Analysis of the non-pe/ppe differential areas against a reference genome defined four main sources of variability, namely: regions of difference (RD), variable genes, duplications and novel genes. RDs and variant analysis segregated the strains into clusters that are concordant with their spoligotype identities. Due to its high homoplasy rate, spoligotyping failed to reflect the true genomic diversity among worldwide representative strains, however, it remains a good indicator for closely related populations. This study introduces a comprehensive population structure analysis of worldwide M. bovis isolates. The incorporation and analysis of 23 novel Uruguayan M. bovis genomes, sheds light onto the genomic diversity of this pathogen, evidencing the existence of greater genetic variability among strains than previously contemplated.

High inter-specimen variability of baseline data for the tibio-talar contact area.

PubMed

Matricali, Giovanni A; Bartels, Ward; Labey, Luc; Dereymaeker, Greta Ph E; Luyten, Frank P; Vander Sloten, Jos

2009-01-01

The tibio-talar contact area has been widely investigated to monitor biomechanical changes due to articular incongruities or an altered loading. This study aims to investigate for the first time in a systematic way the extent of the inter-specimen variability of the tibio-talar contact area, and its repercussions when analyzing data concerning this parameter. Ten specimens were loaded to record the tibio-talar contact characteristics by use of pressure sensitive film. The size of the talar dome area, the size of the (normalized) tibio-talar contact area, the position of the tibio-talar contact area, and the shape of the latter were determined and analyzed. Inter-specimen variability was expressed as the coefficient of variation and was calculated for the datasets of previous studies as well. The size of the tibio-talar contact area showed a very high inter-specimen variability, as is the case in previous studies. This high variability persisted when a normalized tibio-talar contact area was calculated. The shape of the tibio-talar contact area showed some basic characteristics, but a high variation in details could be observed. Every specimen can be considered to have its own "ankle print". By this variability, articular incongruities are expected to have a different effect on local biomechanical characteristics in every single individual. Therefore, every single case has to be evaluated and reported for significant changes. In case of modeling, this also underscores the need to use subject specific models fed by sets of parameters derived from a series of single specimens.

Massive stars: flare activity due to infalls of comet-like bodies

NASA Astrophysics Data System (ADS)

Ibadov, Subhon; Ibodov, Firuz S.

2015-01-01

Passages of comet-like bodies through the atmosphere/chromosphere of massive stars at velocities more than 600 km/s will be accompanied, due to aerodynamic effects as crushing and flattening, by impulse generation of hot plasma within a relatively very thin layer near the stellar surface/photosphere as well as ``blast'' shock wave, i.e., impact-generated photospheric stellar/solar flares. Observational manifestations of such high-temperature phenomena will be eruption of the explosive layer's hot plasma, on materials of the star and ``exploding'' comet nuclei, into the circumstellar environment and variable anomalies in chemical abundances of metal atoms/ions like Fe, Si etc. Interferometric and spectroscopic observations/monitoring of young massive stars with dense protoplanetary discs are of interest for massive stars physics/evolution, including identification of mechanisms for massive stars variability.

Quasi-static rotor morphing concepts for rotorcraft performance improvements

NASA Astrophysics Data System (ADS)

Mistry, Mihir

The current research is focused on two separate quasi-static rotor morphing concepts: Variable span and variable camber. Both concepts were analyzed from the perspective of the performance improvements they allow for, as well as their design requirements. The goal of this body of work is to develop a comprehensive understanding of the benefits and implementation challenges of both systems. For the case of the variable span rotor concept, the effects on aircraft performance were evaluated for a UH-60A type aircraft. The parametric analysis included the performance effects of the rotor span and rotor speed variation, both individually as well as in combination. The design space considered the effect of three different gross weights (16000 lbs, 18300 lbs and 24000 lbs), for a window of +/-11% variation of the rotor speed and a range between +17% to --16% of radius variation (about the baseline) for a range of altitudes. The results of the analysis showed that variable span rotors by themselves are capable of reducing the power requirement of the helicopter by up to 20% for high altitude and gross weight conditions. However, when combined with rotor speed variation, it was possible to reduce the overall power required by the aircraft by up to 30%. Complimentary to the performance analysis, an analytical study of actuation concepts for a variable span rotor was also conducted. This study considered the design of two active actuation systems: Hydraulic pistons and threaded rods (jackscrews), and two passive systems which employed the use of an internal spring type restraining device. For all the configurations considered, it was determined that the design requirements could not be satisfied when considering the constraints defined. The performance improvements due to a variable camber system were evaluated for a BO-105 type rotor in hover. The design space considered included three different thrust levels (4800 lbs, 5500 lbs and 6400 lbs) for a range of altitudes and seven different camber distribution schemes (with up to 10 degrees of camber). Based on the analysis it was shown that variable camber was capable of reducing power up 18% for high thrust levels at high altitudes. Furthermore, it was found that a linearly distributed camber configuration, wherein the maximum camber was at the root, showed the best power reduction. For an untwisted blade (which would be advantageous in high speed flight), introducing spanwise camber variation would result in hover performance levels comparable to a twisted blade. Furthermore, the power reductions calculated were shown to be the result of a reduction of induced power due to the shift of the blade lift inboard due to the direct lift increase as a result of camber variation. The variable camber design presented in the current study exploits the warp-twist relationship of open-section beams. To that effect, a unique actuation structure was developed and implemented in a proof-of-concept variable camber prototype which was built using an existing CH-46E blade section. This prototype was shown to be capable of producing up to 18 degrees of distributed camber with a relatively low input warping of up to 0.18 inches. The results from the specifically developed finite element model of the prototype correlated very well with experimental data. The finite element results indicated the requirement of a shear-deformable core for proper camber deformation in the presence of centrifugal and aerodynamic loads.

Tropical Warm Pool Surface Heat Budgets and Temperature: Contrasts Between 1997-98 El Nino and 1998-99 La Nina

NASA Technical Reports Server (NTRS)

Chou, Shu-Hsien; Chou, Ming-Dah; Chan, Pui-King; Lin, Po-Hsiung; Wang, Kung-Hwa

2003-01-01

Seasonal and interannual variations of the net surface heating F(sub NET) and sea surface temperature tendency (T(sub s)/dt) in the tropical eastern Indian and western Pacific Oceans are studied. The surface heat fluxes are derived from the Special Sensor Microwave/Imager and Japanese Geostationary Meteorological Satellite radiance measurements for the period October 1997-September 2000. It is found that the magnitude of solar heating is lager than that of evaporative cooling, but the spatial variation of the latter is significantly large than the former. As a result, the spatial variations of seasonal and interannual variability of F(sub NET), follow closely that of evaporative cooling. Seasonal variations of F(sub NET) and T(sub s)/dt are significantly correlated, except for the equatorial western Pacific. The high correlation is primarily attributable to high correlation between seasonal cycles of solar heating and T(sub s)/dt. The change of F(sub NET) between 1997-98 El Nino and 1998-99 La Nina is significantly larger in the tropical eastern Indian Ocean than tropical western Pacific. For the former region, the reduced evaporative cooling arising from weakened winds during the El Nino is generally associated with enhanced solar heating due to decreased cloudiness, and thus increases the interannual variability of F(sub NET). For the latter region, the reduced evaporative cooling due to weakened winds is generally associated with but exceeds the reduced solar heating arising from increased cloudiness, and vise versa. Thus the interannual variability of F(sub NET) is reduced due to this offsetting effect. Interannual variations of F(sub NET) and T(sub s)/dt have very low correlation. This is most likely related to interannual variability of ocean dynamics, which includes the variations of solar radiation penetrating through oceanic mixed layer, upwelling of cold thermocline water, Indonesian throughflow for transporting heat from the Pacific to Indian Ocean, and interhemispheric transport in the Indian Ocean.

Trends and variability of water quality in Lake Tana, Ethiopia using MODIS-Aqua

NASA Astrophysics Data System (ADS)

DeLuca, N. M.; Zaitchik, B. F.; Monger, B. C.

2017-12-01

Determining long-term water quality trends and variability in remote inland lakes has been challenging due to a lack of continuous in situ measurements. Utilizing ocean color remote sensing techniques for these lakes is difficult due to their sizes, shapes, and optically complex waters. Lake Tana is the largest body of water in Ethiopia, and is located in the country's northwestern highlands. The lake is quite shallow, averaging at about 8 meters depth, and is characteristically turbid due to nearby land degradation and high soil erosion rates. Lake Tana is an important source of accessible water for the rapidly growing population of Ethiopia and serves as the headwaters for the Blue Nile. Therefore, understanding water quality trends and seasonal variation over the past decade is essential to better preparing for future water needs. Here we use MODIS-Aqua data spanning years 2002-2016 to investigate these trends and variability in Lake Tana, where in situ measurements are limited. Daily water quality products were first processed using SeaDAS and then aggregated by month and year for analyses. Frequent cloud cover in the June, July, and August (JJA) rainy season due to monsoon and zonal dynamics presents an obstacle for obtaining mean lake values during these months. We also performed analyses on targeted regions of Lake Tana to determine whether some of the major tributaries and their corresponding watersheds have more influence on observed trends than others.

Natural wind variability triggered drop in German redispatch volume and costs from 2015 to 2016.

PubMed

Wohland, Jan; Reyers, Mark; Märker, Carolin; Witthaut, Dirk

2018-01-01

Avoiding dangerous climate change necessitates the decarbonization of electricity systems within the next few decades. In Germany, this decarbonization is based on an increased exploitation of variable renewable electricity sources such as wind and solar power. While system security has remained constantly high, the integration of renewables causes additional costs. In 2015, the costs of grid management saw an all time high of about € 1 billion. Despite the addition of renewable capacity, these costs dropped substantially in 2016. We thus investigate the effect of natural climate variability on grid management costs in this study. We show that the decline is triggered by natural wind variability focusing on redispatch as a main cost driver. In particular, we find that 2016 was a weak year in terms of wind generation averages and the occurrence of westerly circulation weather types. Moreover, we show that a simple model based on the wind generation time series is skillful in detecting redispatch events on timescales of weeks and beyond. As a consequence, alterations in annual redispatch costs in the order of hundreds of millions of euros need to be understood and communicated as a normal feature of the current system due to natural wind variability.

Assessment of access to primary health care among children and adolescents hospitalized due to avoidable conditions.

PubMed

Ferrer, Ana Paula Scoleze; Grisi, Sandra Josefina Ferraz Ellero

2016-09-01

Hospitalizations for ambulatory care-sensitive conditions (HACSC) are considered an indicator of the effectiveness of primary health care (PHC). High rates of HACSC represent problems in the access or the quality of health care. In Brazil, HACSC rates are high and there are few studies on the factors associated with it. To evaluate the access to PHC offered to children and adolescents hospitalized due to ACSC and analyze the conditioning factors. Cross-sectional study with a quantitative and qualitative approach. Five hundred and one (501) users (guardians/caregivers) and 42 professionals of PHC units were interviewed over one year. Quantitative data were obtained using Primary Care Assessment Tool validated in Brazil (PCATool-Brazil), while qualitative data were collected by semi-structured interview. The independent variables were: age, maternal education, family income, type of diagnosis, and model of care offered, and the dependent variables were access and its components (accessibility and use of services). Sixty-five percent (65.2%) of hospitalizations were ACSC. From the perspective of both users and professionals, access and its components presented low scores. Age, type of diagnosis, and model of care affected the results. The proportion of HACSC was high in this population. Access to services is inappropriate due to: barriers to access, appreciation of the emergency services, and attitude towards health needs. Professional attitudes and opinions reinforce inadequate ideas of users reflecting on the pattern of service use.

Comparison of Bioclimatic, NDVI and Elevation variables in assessing extent of Commiphora wightii (Arnt.) Bhand.

NASA Astrophysics Data System (ADS)

Kulloli, R. N.; Kumar, S.

2014-11-01

Commiphora wightii (Arnt.) Bhand., is an important medicinal plant of Indian Medicine System (IMS) since ancient time. It is used in different ailments of obesity, arthritis, rheumatism and high cholesterol. Due to overexploitation its natural populations declined to large extent. IUCN has put it under Data Deficient (DD) category due to lack of data on its extent of occurrence in nature. Hence, the study was carried out using MaxEnt distribution modelling algorithm to estimate its geographic distribution and to identify potential habitats for its reintroduction. For modelling employed 68 presence locality data, 19 bioclimatic variables, Normalize Difference Vegetation Index (NDVI) and elevation data. These were tested for multicollinearity and those variables having r-value less than 0.8 were selected for further analysis, which was carried out in two ways i) Bioclimatic variables and elevation; ii) NDVI and elevation. Area Under the Curve (AUC) in both analysis was above 0.9 for all variables, indicating very high accuracy of prediction. Variables governing distribution of C. wightii in the analysis using bioclimatic and elevation data set are precipitation seasonality (56.6 %), annual precipitation (16.4 %) and elevation (14.7 %). Extent of occurrence of C.wightii predicted by model closely matched in the districts of Jaisalmer and Barmer. In the second analysis elevation (48.3 %), NDVI of June (11.1 %) and August (11.2 %) contributed for NDVI and Elevation data set. NDVI of June corresponds to its leafing phase while NDVI of August to flowering phase. Area of its occurrence predicted for NDVI and elevation data set are Bikaner, Churu, Jhunjhunun some part of Jodhpur which are completely sandy, where C. wightii is totally absent. Extent of occurrence was also validated in ground survey. Potential areas for its reintroduction were identified as Jaisalmer and Barmer districts in Indian arid zone.

Turbidity threshold sampling: Methods and instrumentation

Treesearch

Rand Eads; Jack Lewis

2001-01-01

Traditional methods for determining the frequency of suspended sediment sample collection often rely on measurements, such as water discharge, that are not well correlated to sediment concentration. Stream power is generally not a good predictor of sediment concentration for rivers that transport the bulk of their load as fines, due to the highly variable routing of...

Highly Accurate Antibody Assays for Early and Rapid Detection of Tuberculosis in African and Asian Elephants

USDA-ARS?s Scientific Manuscript database

Tuberculosis (TB) in elephants is a re-emerging zoonotic disease caused primarily by Mycobacterium tuberculosis. Current methods for screening and diagnosis rely on trunk wash culture, which has serious limitations due to low test sensitivity, slow turn-around time, and variable sample quality. Inn...

The Debate on Maturational Constraints in Bilingual Development: A Perspective from First-Language Attrition

ERIC Educational Resources Information Center

Schmid, Monika S.

2014-01-01

A controversial topic in research on second-language acquisition is whether residual variability and optionality in high-proficiency late second-language (L2) learners is merely the outcome of cross-linguistic transfer, competition, and processing limitations, or whether late learners have an underlying representational deficit due to maturational…

Behavioral Repertoire of Xenopus tropicalis: Baseline Female-male Interactions during Spawning Events and Male Vocal Communication

EPA Science Inventory

The aquatic frog, Xenopus tropicalis, is being developed for use as a model amphibian species for inclusion in the EPA’s Endocrine Disruptor Screening Program. Current toxicity test designs do not incorporate measures of fecundity due to high variability in the responses of frog...

The Application of Function Points to Predict Source Lines of Code for Software Development

DTIC Science & Technology

1992-09-01

there are some disadvantages. Software estimating tools are expensive. A single tool may cost more than $15,000 due to the high market value of the...term and Lang variables simultaneously onlN added marginal improvements over models with these terms included singularly. Using all the available

Spatial and temporal distribution of trunk-injected 14C-Imidacloprid in Fraxinus trees

Treesearch

Sara R. Tanis; Bert M. Cregg; David Mota-Sanchez; Deborah G. McCullough; Therese M. Poland

2012-01-01

BACKGROUND: Since the discovery of Agrilus planipennis Fairmaire (emerald ash borer) in 2002, researchers have tested several methods of chemical control. Soil drench or trunk injection products containing imidacloprid are commonly used to control adults. However, efficacy can be highly variable andmay be due to uneven translocation of systemic...

Extrusion-spheronization: process variables and characterization.

PubMed

Sinha, V R; Agrawal, M K; Agarwal, A; Singh, G; Ghai, D

2009-01-01

Multiparticulate systems have undergone great development in the past decade fueled by the better understanding of their multiple roles as a suitable delivery system. With the passage of time, significant advances have been made in the process of pelletization due to the incorporation of specialized techniques for their development. Extrusion-spheronization seems to be the most promising process for the optimum delivery of many potent drugs having high systemic toxicity. It also offers immense pharmaceutical applicability due to the benefits of high loading capacity of active ingredient(s), narrow size distribution, and cost-effectiveness. On application of a specific coat, these systems can also aid in site-specific delivery, thereby enhancing the bioavailability of many drugs. The current review focuses on the process of extrusion-spheronization and the operational (extruder types, screen pressure, screw speed, temperature, moisture content, spheronization load, speed and time) and formulation (excipients and drugs) variables, which may affect the quality of the final pellets. Various methods for the evaluation of the quality of the pellets with regard to the size distribution, shape, friability, granule strength, density, porosity, flow properties, and surface texture are discussed.

[Big data in imaging].

PubMed

Sewerin, Philipp; Ostendorf, Benedikt; Hueber, Axel J; Kleyer, Arnd

2018-04-01

Until now, most major medical advancements have been achieved through hypothesis-driven research within the scope of clinical trials. However, due to a multitude of variables, only a certain number of research questions could be addressed during a single study, thus rendering these studies expensive and time consuming. Big data acquisition enables a new data-based approach in which large volumes of data can be used to investigate all variables, thus opening new horizons. Due to universal digitalization of the data as well as ever-improving hard- and software solutions, imaging would appear to be predestined for such analyses. Several small studies have already demonstrated that automated analysis algorithms and artificial intelligence can identify pathologies with high precision. Such automated systems would also seem well suited for rheumatology imaging, since a method for individualized risk stratification has long been sought for these patients. However, despite all the promising options, the heterogeneity of the data and highly complex regulations covering data protection in Germany would still render a big data solution for imaging difficult today. Overcoming these boundaries is challenging, but the enormous potential advances in clinical management and science render pursuit of this goal worthwhile.

Practical procedure for discriminating monofloral honey with a broad pollen profile variability using an electronic tongue.

PubMed

Sousa, Mara E B C; Dias, Luís G; Veloso, Ana C A; Estevinho, Letícia; Peres, António M; Machado, Adélio A S C

2014-10-01

Colour and floral origin are key parameters that may influence the honey market. Monofloral light honey are more demanded by consumers, mainly due to their flavour, being more valuable for producers due to their higher price when compared to darker honey. The latter usually have a high anti-oxidant content that increases their healthy potential. This work showed that it is possible to correctly classify monofloral honey with a high variability in floral origin with a potentiometric electronic tongue after making a preliminary selection of honey according their colours: white, amber and dark honey. The results showed that the device had a very satisfactory sensitivity towards floral origin (Castanea sp., Echium sp., Erica sp., Lavandula sp., Prunus sp. and Rubus sp.), allowing a leave-one-out cross validation correct classification of 100%. Therefore, the E-tongue shows potential to be used at analytical laboratory level for honey samples classification according to market and quality parameters, as a practical tool for ensuring monofloral honey authenticity. Copyright © 2014 Elsevier B.V. All rights reserved.

Memory Variability Is Due to the Contribution of Recollection and Familiarity, Not to Encoding Variability

ERIC Educational Resources Information Center

Koen, Joshua D.; Yonelinas, Andrew P.

2010-01-01

It is well established that the memory strength of studied items is more variable than the strength of new items on tests of recognition memory, but the reason why this occurs is poorly understood. One account for this old "item variance effect" is based on single-process theory, which proposes that this effect is due to variability in how well…

Variable photonic crystal fiber optical attenuator combining air hole reduction induced radiation and bending loss

NASA Astrophysics Data System (ADS)

Yokota, Hirohisa; Sano, Tomohiko; Imai, Yoh

2018-06-01

Recently, an optical attenuator has been important in fiber optic communication systems, because a transmission power in fiber has become higher due to a channel increment in wavelength division multiplexing transmission. A photonic crystal fiber (PCF) optical attenuator is fabricated by air hole diameter reduction in a part of PCF in which radiations are caused in the air hole diameter reduced part of PCF. A PCF optical attenuator has a high power resistance feature due to its radiation-induced operation of optical attenuation. In this paper, we proposed a variable PCF optical attenuator in which a bend was applied to the air hole diameter reduced part in PCF optical attenuator that was fabricated by CO2 laser irradiation. In PCF optical attenuator fabrication, the attenuation was adjusted by the reduced air hole diameter with laser irradiation time control. It was demonstrated that 10.6-13.5 dB of variable attenuation was obtained at 1550 nm-wavelength with 0°-90° bending angle applied to the air hole diameter reduced part in PCF optical attenuator.

Variable photonic crystal fiber optical attenuator combining air hole reduction induced radiation and bending loss

NASA Astrophysics Data System (ADS)

Yokota, Hirohisa; Sano, Tomohiko; Imai, Yoh

2018-02-01

Recently, an optical attenuator has been important in fiber optic communication systems, because a transmission power in fiber has become higher due to a channel increment in wavelength division multiplexing transmission. A photonic crystal fiber (PCF) optical attenuator is fabricated by air hole diameter reduction in a part of PCF in which radiations are caused in the air hole diameter reduced part of PCF. A PCF optical attenuator has a high power resistance feature due to its radiation-induced operation of optical attenuation. In this paper, we proposed a variable PCF optical attenuator in which a bend was applied to the air hole diameter reduced part in PCF optical attenuator that was fabricated by CO2 laser irradiation. In PCF optical attenuator fabrication, the attenuation was adjusted by the reduced air hole diameter with laser irradiation time control. It was demonstrated that 10.6-13.5 dB of variable attenuation was obtained at 1550 nm-wavelength with 0°-90° bending angle applied to the air hole diameter reduced part in PCF optical attenuator.

Influence of CYP3A5 genetic variation on everolimus maintenance dosing after cardiac transplantation.

PubMed

Lesche, Dorothea; Sigurdardottir, Vilborg; Setoud, Raschid; Englberger, Lars; Fiedler, Georg M; Largiadèr, Carlo R; Mohacsi, Paul; Sistonen, Johanna

2015-12-01

Everolimus (ERL) has become an alternative to calcineurin inhibitors (CNIs) due to its renal-sparing properties, especially in heart transplant (HTx) recipients with kidney dysfunction. However, ERL dosing is challenging due to its narrow therapeutic window combined with high interindividual pharmacokinetic variability. Our aim was to evaluate the effect of clinical and genetic factors on ERL dosing in a pilot cohort of 37 HTx recipients. Variants in CYP3A5, CYP3A4, CYP2C8, POR, NR1I2, and ABCB1 were genotyped, and clinical data were retrieved from patient charts. While ERL trough concentration (C0 ) was within the targeted range for most patients, over 30-fold variability in the dose-adjusted ERL C0 was observed. Regression analysis revealed a significant effect of the non-functional CYP3A5*3 variant on the dose-adjusted ERL C0 (p = 0.031). ERL dose requirement was 0.02 mg/kg/d higher in patients with CYP3A5*1/*3 genotype compared to patients with CYP3A5*3/*3 to reach the targeted C0 (p = 0.041). ERL therapy substantially improved estimated glomerular filtration rate (28.6 ± 6.6 mL/min/1.73 m(2)) in patients with baseline kidney dysfunction. Everolimus pharmacokinetics in HTx recipients is highly variable. Our preliminary data on patients on a CNI-free therapy regimen suggest that CYP3A5 genetic variation may contribute to this variability. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Control of variable speed variable pitch wind turbine based on a disturbance observer

NASA Astrophysics Data System (ADS)

Ren, Haijun; Lei, Xin

2017-11-01

In this paper, a novel sliding mode controller based on disturbance observer (DOB) to optimize the efficiency of variable speed variable pitch (VSVP) wind turbine is developed and analyzed. Due to the highly nonlinearity of the VSVP system, the model is linearly processed to obtain the state space model of the system. Then, a conventional sliding mode controller is designed and a DOB is added to estimate wind speed. The proposed control strategy can successfully deal with the random nature of wind speed, the nonlinearity of VSVP system, the uncertainty of parameters and external disturbance. Via adding the observer to the sliding mode controller, it can greatly reduce the chattering produced by the sliding mode switching gain. The simulation results show that the proposed control system has the effectiveness and robustness.

Variability of GPS-derived running performance during official matches in elite professional soccer players.

PubMed

Al Haddad, Hani; Méndez-Villanueva, Alberto; Torreño, Nacho; Munguía-Izquierdo, Diego; Suárez-Arrones, Luis

2017-09-22

The aim of this study was to assess the match-to-match variability obtained using GPS devices, collected during official games in professional soccer players. GPS-derived data from nineteen elite soccer players were collected over two consecutive seasons. Time-motion data for players with more than five full-match were analyzed (n=202). Total distance covered (TD), TD >13-18 km/h, TD >18-21 km/h, TD >21 km/h, number of acceleration >2.5-4 m.s-2 and >4 m.s-2 were calculated. The match-to-match variation in running activity was assessed by the typical error expressed as a coefficient of variation (CV,%) and the magnitude of the CV was calculated (effect size). When all players were pooled together, CVs ranged from 5% to 77% (first half) and from 5% to 90% (second half), for TD and number of acceleration >4 m.s-2, and the magnitude of the CVs were rated from small to moderate (effect size = 0.57-0.98). The CVs were likely to increase with running/acceleration intensity, and were likely to differ between playing positions (e.g., TD > 13-18 km/h 3.4% for second strikers vs 14.2% for strikers and 14.9% for wide-defenders vs 9.7% for wide-midfielders). Present findings indicate that variability in players' running performance is high in some variables and likely position-dependent. Such variability should be taken into account when using these variables to prescribe and/or monitor training intensity/load. GPS-derived match-to-match variability in official games' locomotor performance of professional soccer players is high in some variables, particularly for high-speed running, due to the complexity of match running performance and its most influential factors and reliability of the devices.

Variable Lifting Index (VLI): A New Method for Evaluating Variable Lifting Tasks.

PubMed

Waters, Thomas; Occhipinti, Enrico; Colombini, Daniela; Alvarez-Casado, Enrique; Fox, Robert

2016-08-01

We seek to develop a new approach for analyzing the physical demands of highly variable lifting tasks through an adaptation of the Revised NIOSH (National Institute for Occupational Safety and Health) Lifting Equation (RNLE) into a Variable Lifting Index (VLI). There are many jobs that contain individual lifts that vary from lift to lift due to the task requirements. The NIOSH Lifting Equation is not suitable in its present form to analyze variable lifting tasks. In extending the prior work on the VLI, two procedures are presented to allow users to analyze variable lifting tasks. One approach involves the sampling of lifting tasks performed by a worker over a shift and the calculation of the Frequency Independent Lift Index (FILI) for each sampled lift and the aggregation of the FILI values into six categories. The Composite Lift Index (CLI) equation is used with lifting index (LI) category frequency data to calculate the VLI. The second approach employs a detailed systematic collection of lifting task data from production and/or organizational sources. The data are organized into simplified task parameter categories and further aggregated into six FILI categories, which also use the CLI equation to calculate the VLI. The two procedures will allow practitioners to systematically employ the VLI method to a variety of work situations where highly variable lifting tasks are performed. The scientific basis for the VLI procedure is similar to that for the CLI originally presented by NIOSH; however, the VLI method remains to be validated. The VLI method allows an analyst to assess highly variable manual lifting jobs in which the task characteristics vary from lift to lift during a shift. © 2015, Human Factors and Ergonomics Society.

Covariability of seasonal temperature and precipitation over the Iberian Peninsula in high-resolution regional climate simulations (1001-2099)

NASA Astrophysics Data System (ADS)

Fernández-Montes, S.; Gómez-Navarro, J. J.; Rodrigo, F. S.; García-Valero, J. A.; Montávez, J. P.

2017-04-01

Precipitation and surface temperature are interdependent variables, both as a response to atmospheric dynamics and due to intrinsic thermodynamic relationships and feedbacks between them. This study analyzes the covariability of seasonal temperature (T) and precipitation (P) across the Iberian Peninsula (IP) using regional climate paleosimulations for the period 1001-1990, driven by reconstructions of external forcings. Future climate (1990-2099) was simulated according to SRES scenarios A2 and B2. These simulations enable exploring, at high spatial resolution, robust and physically consistent relationships. In winter, positive P-T correlations dominate west-central IP (Pearson correlation coefficient ρ = + 0.43, for 1001-1990), due to prevalent cold-dry and warm-wet conditions, while this relationship weakens and become negative towards mountainous, northern and eastern regions. In autumn, negative correlations appear in similar regions as in winter, whereas for summer they extend also to the N/NW of the IP. In spring, the whole IP depicts significant negative correlations, strongest for eastern regions (ρ = - 0.51). This is due to prevalent frequency of warm-dry and cold-wet modes in these regions and seasons. At the temporal scale, regional correlation series between seasonal anomalies of temperature and precipitation (assessed in 31 years running windows in 1001-1990) show very large multidecadal variability. For winter and spring, periodicities of about 50-60 years arise. The frequency of warm-dry and cold-wet modes appears correlated with the North Atlantic Oscillation (NAO), explaining mainly co-variability changes in spring. For winter and some regions in autumn, maximum and minimum P-T correlations appear in periods with enhanced meridional or easterly circulation (low or high pressure anomalies in the Mediterranean and Europe). In spring and summer, the Atlantic Multidecadal Oscillation shows some fingerprint on the frequency of warm/cold modes. For future scenarios, an intensification of the negative P-T relationship is generally found, as a result of an increased frequency of the warm-dry mode.

Structure-based engineering to restore high affinity binding of an isoform-selective anti-TGFβ1 antibody

PubMed Central

Honey, Denise M.; Best, Annie; Qiu, Huawei

2018-01-01

ABSTRACT Metelimumab (CAT192) is a human IgG4 monoclonal antibody developed as a TGFβ1-specific antagonist. It was tested in clinical trials for the treatment of scleroderma but later terminated due to lack of efficacy. Subsequent characterization of CAT192 indicated that its TGFβ1 binding affinity was reduced by ∼50-fold upon conversion from the parental single-chain variable fragment (scFv) to IgG4. We hypothesized this result was due to decreased conformational flexibility of the IgG that could be altered via engineering. Therefore, we designed insertion mutants in the elbow region and screened for binding and potency. Our results indicated that increasing the elbow region linker length in each chain successfully restored the isoform-specific and high affinity binding of CAT192 to TGFβ1. The crystal structure of the high binding affinity mutant displays large conformational rearrangements of the variable domains compared to the wild-type antigen-binding fragment (Fab) and the low binding affinity mutants. Insertion of two glycines in both the heavy and light chain elbow regions provided sufficient flexibility for the variable domains to extend further apart than the wild-type Fab, and allow the CDR3s to make additional interactions not seen in the wild-type Fab structure. These interactions coupled with the dramatic conformational changes provide a possible explanation of how the scFv and elbow-engineered Fabs bind TGFβ1 with high affinity. This study demonstrates the benefits of re-examining both structure and function when converting scFv to IgG molecules, and highlights the potential of structure-based engineering to produce fully functional antibodies. PMID:29333938

Primary productivity and its variability in the equatorial South China Sea during the northeast monsoon

NASA Astrophysics Data System (ADS)

Ooi, S. H.; Samah, A. A.; Braesicke, P.

2013-08-01

Near coastal areas of the equatorial South China Sea (SCS) are one of the world's regions with highest primary productivity (phytoplankton growth). Concentrations of phytoplankton in the SCS depend significantly on atmospheric forcings and the oceanic state, in particular during the northeast (winter) monsoon season from November to March. Aided by new ocean-observing satellite data, we present a climatological overview of recent surface atmospheric and oceanic features in the equatorial SCS during the northeast monsoon to identify the dominant air-sea processes influencing and modulating the primary productivity of the region. Measured chlorophyll a concentrations are used as a proxy for phytoplankton amounts and the spatial and temporal variations are characterized according to meteorological conditions. Converging northeasterly surface winds support high chlorophyll a concentrations along East Malaysia's coastline in conjunction with a continual nutrient supply from the bottom of the continental shelf by vertical mixing. The mixing can be enhanced due to increased turbulence by wind-generated high waves when they approach shallow water from the deep basin during strong cold surges and monsoon disturbances. Intraseasonal variability during the winter monsoon is characterized by a coastal increase of chlorophyll a starting in November and peaking in January. A general decrease is observed in March. Interannual variability of chlorophyll a concentrations is influenced by ENSO (due to the known modulation of cold surge occurrences), with decreases during El Niño and increases during La Niña in early winter along the shore of East Malaysia. As an example, we discuss an enhanced phytoplankton growth event that occurred due to a typical cold surge-induced Borneo vortex event in January 2010.

Experimental evaluation of fog warning system.

PubMed

Al-Ghamdi, Ali S

2007-11-01

Highway safety is a major concern to the public and to transportation professionals, so the number of crashes caused by poor visibility due to fog form an alarming statistic. Drivers respond to poor visibility conditions in different ways: some slow down; others do not. Many drivers simply follow the taillights of the vehicle ahead. Accordingly, hazardous conditions are created in which speeds are both too high for the prevailing conditions and highly variable. Findings are presented from a study of traffic crashes due to fog in the southern region of Saudi Arabia. The primary objective was to assess the effectiveness of fog detection and warning system on driver behavior regarding speed and headway. This warning system includes visibility sensors that automatically activate a variable message sign that posts an advisory speed when hazardous conditions due to fog occur. The system was installed on a 2 km section of a two-lane, rural highway. A data set of 36,013 observations from both experimental and control sections at two study sites was collected and analyzed. The data included vehicle speed, volume, and classification; time headway, time of day, and visibility distance. Although the warning system was ineffective in reducing speed variability, mean speed throughout the experimental sections was reduced by about 6.5 kph. This reduction indicates that the warning system appeared to have a positive effect on driver behavior in fog even though the observed mean speeds were still higher than the posted advisory speed. From relationships found in the literature between mean driving speed and number of crashes, a speed reduction of only 5 kph would yield a 15% decrease in the number of crashes.

The accuracy of estimates of the overturning circulation from basin-wide mooring arrays

NASA Astrophysics Data System (ADS)

Sinha, B.; Smeed, D. A.; McCarthy, G.; Moat, B. I.; Josey, S. A.; Hirschi, J. J.-M.; Frajka-Williams, E.; Blaker, A. T.; Rayner, D.; Madec, G.

2018-01-01

Previous modeling and observational studies have established that it is possible to accurately monitor the Atlantic Meridional Overturning Circulation (AMOC) at 26.5°N using a coast-to-coast array of instrumented moorings supplemented by direct transport measurements in key boundary regions (the RAPID/MOCHA/WBTS Array). The main sources of observational and structural errors have been identified in a variety of individual studies. Here a unified framework for identifying and quantifying structural errors associated with the RAPID array-based AMOC estimates is established using a high-resolution (eddy resolving at low-mid latitudes, eddy permitting elsewhere) ocean general circulation model, which simulates the ocean state between 1978 and 2010. We define a virtual RAPID array in the model in close analogy to the real RAPID array and compare the AMOC estimate from the virtual array with the true model AMOC. The model analysis suggests that the RAPID method underestimates the mean AMOC by ∼1.5 Sv (1 Sv = 106 m3 s-1) at ∼900 m depth, however it captures the variability to high accuracy. We examine three major contributions to the streamfunction bias: (i) due to the assumption of a single fixed reference level for calculation of geostrophic transports, (ii) due to regions not sampled by the array and (iii) due to ageostrophic transport. A key element in (i) and (iii) is use of the model sea surface height to establish the true (or absolute) geostrophic transport. In the upper 2000 m, we find that the reference level bias is strongest and most variable in time, whereas the bias due to unsampled regions is largest below 3000 m. The ageostrophic transport is significant in the upper 1000 m but shows very little variability. The results establish, for the first time, the uncertainty of the AMOC estimate due to the combined structural errors in the measurement design and suggest ways in which the error could be reduced. Our work has applications to basin-wide circulation measurement arrays at other latitudes and in other basins as well as quantifying systematic errors in ocean model estimates of the AMOC at 26.5°N.

Relationships between pediatric asthma and socioeconomic/urban variables in Baltimore, Maryland

NASA Technical Reports Server (NTRS)

Kimes, Daniel; Ullah, Asad; Levine, Elissa; Nelson, Ross; Timmins, Sidey; Weiss, Sheila; Bollinger, Mary E.; Blaisdell, Carol

2004-01-01

Spatial relationships between clinical data for pediatric asthmatics (hospital and emergency department utilization rates), and socioeconomic and urban characteristics in Baltimore City were analyzed with the aim of identifying factors that contribute to increased asthma rates. Socioeconomic variables and urban characteristics derived from satellite data explained 95% of the spatial variation in hospital rates. The proportion of families headed by a single female was the most important variable accounting for 89% of the spatial variation. Evidence suggests that the high rates of hospital admissions and emergency department (ED) visits may partially be due to the difficulty of single parents with limited resources managing their child's asthma condition properly. This knowledge can be used for education towards mitigating ED and hospital events in Baltimore City.

X-ray Weak Broad-line Qquasars: Absorption or Intrinsic X-ray Weakness

NASA Technical Reports Server (NTRS)

Mushotzky, Richard (Technical Monitor); Risaliti, Guida

2005-01-01

XMM observations of X-ray weak quasars have been performed during 2003 and 2004. The data for all the observations have become available in 2004 (there has been a delay of several months on the initial schedule, due to high background flares which contaminated the observations: as a consequence, most of them had to be rescheduled). We have reduced and analyzed all the data, and obtained interesting scientific results. Out of the eight sources, 4 are confirmed to be extremely X-ray weak, in agreement with the results of previous Chandra observations. 3 sources are confined to be highly variable both in flux (by factor 20-50) and in spectral properties (dramatic changes in spectral index). For both these groups of objects we are completing a publication: 1) For the X-ray weak sources, a paper is submitted with a complete analysis of the X-ray spectra both from Chandra and XMM-Newton, and a comparison with optical and near-IR photometry obtained from all-sky surveys. Possible models for the unusual spectral energy distribution of these sources are also presented. 2) For the variable sources, a paper is being finalized where the X-ray spectra obtained with XMM-Newton are compared with previous X-ray observations and with observations at other wavelengths. It is shown that these sources are high luminosity and extreme cases of the highly variable class of narrow-line Seyfert Is. In order to further understand the nature of these X-ray weak quasars, we submitted proposals for spectroscopy at optical and infrared telescopes. We obtained time at the TNG 4 meter telescope for near-IR observations and at the Hobby-Eberly Telescope for optical high-resolution spectroscopy. These observations have been performed in early 2004. They will complement the XMM data and will lead to understanding of whether the X-ray weakness of these sources is an intrinsic property or is due to absorption by circum-nuclear material. The infrared spectra of the variable sources have been already analyzed and are discussed in the paper by Memola et al. which will be soon submitted.

Quantifying variabilty of the solar resource using the Kriging method

NASA Astrophysics Data System (ADS)

Monger, Samuel Haze

Energy consumption will steadily rise in coming years and if fossil fuels, particularly coal, continue to be the primary resource for electricity generation our planet is going to face many hardships. Solar energy is the most abundant resource available to humankind, and although solar generated power is still expensive, the technology is in a state of rapid development as governments strive to meet renewable energy goals as part of the effort to slow climate change and become less dependent on finite resources. However there are many valid concerns associated with integrating high levels of solar energy with the transmission grid due to the rapid changes in power output and voltage from photovoltaic generated electricity due to drops in the solar resource. Therefore, a study was conducted to address issues in this field of research by attempting to quantify the variability of solar irradiance at a specific area using a uniform grid of 45 irradiance sensors. Another goal of this study was to determine if fewer measurement stations could be used in the quantification of variability. This thesis addresses these issues by using the Sandia Variability Index and the dead band ramp algorithm in a statistical analysis on irradiance fluctuations in the regulation and sub-regulation time frames. A kriging method will be introduced which accurately predicts variability using only four stations.

Formulation, in vitro evaluation and study of variables on tri-layered gastro-retentive delivery system of diltiazem HCl.

PubMed

Raut Desai, Shilpa; Rohera, Bhagwan D

2014-03-01

Tri-layered floating tablets using only one grade of polyethylene oxide (PEO) would enable easy manufacturing, reproducibility and controlled release for highly soluble drugs. To evaluate the potential of PEO as a sole polymer for the controlled release and to study the effect of formulation variables on release and gastric retention of highly soluble Diltiazem hydrochloride (DTZ). Tablets were compressed with middle layer consisting of drug and polymer while outer layers consisted of polymer with sodium bicarbonate. Design of formulation to obtain 12 h, zero-order release and rapid floatation was done by varying the grades, quantity of PEO and sodium bicarbonate. Dissolution data were fitted in drug release models and swelling/erosion studies were undertaken to verify the drug release mechanism. Effect of formulation variables and tablet surface morphology using scanning electron microscopy were studied. The optimized formula passed the criteria of USP dissolution test I and exhibited floating lag-time of 3-4 min. Drug release was faster from low molecular weight (MW) PEO as compared to high MW. With an increase in the amount of sodium bicarbonate, faster buoyancy was achieved due to the increased CO2 gas formation. Drug release followed zero-order and gave a good fit to the Korsmeyer-Peppas model, which suggested that drug release was due to diffusion through polymer swelling. Zero-order, controlled release profile with the desired buoyancy can be achieved by using optimum formula quantities of sodium bicarbonate and polymer. The tri-layered system shows promising delivery of DTZ, and possibly other water-soluble drugs.

Elevated Blood Neutrophil-to-Lymphocyte Ratio: A Readily Available Biomarker Associated with Death due to Disease in High Risk Nonmetastatic Melanoma.

PubMed

Davis, Jeremy L; Langan, Russell C; Panageas, Katherine S; Zheng, Junting; Postow, Michael A; Brady, Mary S; Ariyan, Charlotte; Coit, Daniel G

2017-07-01

Elevated peripheral blood neutrophil-to-lymphocyte ratio (NLR) is associated with poor oncologic outcomes in patients with stage IV melanoma and other solid tumors, but its impact has not been characterized for patients with high-risk, nonmetastatic melanoma. Retrospective review of a melanoma database identified patients with high-risk melanoma who underwent operation with curative intent at a single institution. NLR was calculated from blood samples obtained within 2 weeks before operation. Multiple primary melanomas and concurrent hematologic or other metastatic malignancies were excluded. Cumulative incidence of death due to disease was estimated, and Gray's test was used to examine the effect of NLR on melanoma disease-specific death (DOD). Multivariable competing risks regression models assessed associated factors. Data on 1431 patients with high-risk, nonmetastatic melanoma were analyzed. Median follow-up for survivors was 4 years. High NLR (≥3 or as continuous variable) was associated with older age, male sex, thicker primaries, higher mitotic index, and more advanced nodal status. On multivariate analysis, high NLR (≥3 or as a continuous variable), older age, male sex, ulcerated primary, lymphovascular invasion, and positive nodal status were all independently associated with worse DOD. NLR is a readily available blood test that was independently associated with DOD in patients with high-risk, nonmetastatic melanoma. It is unclear whether high NLR is a passive indicator of poor prognosis or a potential therapeutic target. Further studies to evaluate the prognostic role of NLR to potentially identify those more likely to benefit from adjuvant immunotherapy may prove informative.

Visualization of Heart Rate Variability of Long-Term Heart Transplant Patient by Transition Networks: A Case Report.

PubMed

Wdowczyk, Joanna; Makowiec, Danuta; Dorniak, Karolina; Gruchała, Marcin

2016-01-01

We present a heart transplant patient at his 17th year of uncomplicated follow-up. Within a frame of routine check out several tests were performed. With such a long and uneventful follow-up some degree of graft reinnervation could be anticipated. However, the patient's electrocardiogram and exercise parameters seemed largely inconclusive in this regard. The exercise heart rate dynamics were suggestive of only mild, if any parasympathetic reinnervation of the graft with persisting sympathetic activation. On the other hand, traditional heart rate variability (HRV) indices were inadequately high, due to erratic rhythm resulting from interference of the persisting recipient sinus node or non-conducted atrial parasystole. New tools, originated from network representation of time series, by visualization short-term dynamical patterns, provided a method to discern HRV increase due to reinnervation from other reasons.

Body mass index as a predictor of firefighter injury and workers' compensation claims.

PubMed

Kuehl, Kerry S; Kisbu-Sakarya, Yasemin; Elliot, Diane L; Moe, Esther L; Defrancesco, Carol A; Mackinnon, David P; Lockhart, Ginger; Goldberg, Linn; Kuehl, Hannah E

2012-05-01

To determine the relationship between lifestyle variables including body mass index and filing a workers' compensation claim due to firefighter injury. A cross-sectional evaluation of firefighter injury related to workers" compensation claims occurring 5 years after the original Promoting Healthy Lifestyles: Alternative Models' Effects study intervention. A logistic regression analysis for variables predicting filing a workers' compensation claim due to an injury was performed with a total of 433 participants. The odds of filing a compensation claim were almost 3 times higher for firefighters with a body mass index of more than 30 kg/m than firefighters with a normal body mass index (odds ratio, 2.89; P < 0.05). This study addresses a high-priority area of reducing firefighter injuries and workers' compensation claims. Maintaining a healthy body weight is important to reduce injury and workers' compensation claims among firefighters.

Added-values of high spatiotemporal remote sensing data in crop yield estimation

NASA Astrophysics Data System (ADS)

Gao, F.; Anderson, M. C.

2017-12-01

Timely and accurate estimation of crop yield before harvest is critical for food market and administrative planning. Remote sensing derived parameters have been used for estimating crop yield by using either empirical or crop growth models. The uses of remote sensing vegetation index (VI) in crop yield modeling have been typically evaluated at regional and country scales using coarse spatial resolution (a few hundred to kilo-meters) data or assessed over a small region at field level using moderate resolution spatial resolution data (10-100m). Both data sources have shown great potential in capturing spatial and temporal variability in crop yield. However, the added value of data with both high spatial and temporal resolution data has not been evaluated due to the lack of such data source with routine, global coverage. In recent years, more moderate resolution data have become freely available and data fusion approaches that combine data acquired from different spatial and temporal resolutions have been developed. These make the monitoring crop condition and estimating crop yield at field scale become possible. Here we investigate the added value of the high spatial and temporal VI for describing variability of crop yield. The explanatory ability of crop yield based on high spatial and temporal resolution remote sensing data was evaluated in a rain-fed agricultural area in the U.S. Corn Belt. Results show that the fused Landsat-MODIS (high spatial and temporal) VI explains yield variability better than single data source (Landsat or MODIS alone), with EVI2 performing slightly better than NDVI. The maximum VI describes yield variability better than cumulative VI. Even though VI is effective in explaining yield variability within season, the inter-annual variability is more complex and need additional information (e.g. weather, water use and management). Our findings augment the importance of high spatiotemporal remote sensing data and supports new moderate resolution satellite missions for agricultural applications.

Comparing interpolation techniques for annual temperature mapping across Xinjiang region

NASA Astrophysics Data System (ADS)

Ren-ping, Zhang; Jing, Guo; Tian-gang, Liang; Qi-sheng, Feng; Aimaiti, Yusupujiang

2016-11-01

Interpolating climatic variables such as temperature is challenging due to the highly variable nature of meteorological processes and the difficulty in establishing a representative network of stations. In this paper, based on the monthly temperature data which obtained from the 154 official meteorological stations in the Xinjiang region and surrounding areas, we compared five spatial interpolation techniques: Inverse distance weighting (IDW), Ordinary kriging, Cokriging, thin-plate smoothing splines (ANUSPLIN) and Empirical Bayesian kriging(EBK). Error metrics were used to validate interpolations against independent data. Results indicated that, the ANUSPLIN performed best than the other four interpolation methods.

The analysis of Stability reliability of Qian Tang River seawall

NASA Astrophysics Data System (ADS)

Wu, Xue-Xiong

2017-11-01

Qiantang River seawall due to high water soaking pond by foreshore scour, encountered during the low tide prone slope overall instability. Considering the seawall beach scour in front of random change, using the simplified Bishop method, combined with the variability of soil mechanics parameters, calculation and analysis of Qiantang River Xiasha seawall segments of the overall stability.

Crowding and Neighborhood Mediation of Urban Density.

ERIC Educational Resources Information Center

Baum, Andrew; And Others

The study of density and crowding has expanded rapidly, due in part to concern about the impact of high density on the quality of life. In this paper results of a study which focused upon the intervening role of neighborhood variables in the experience of urban density are reported. Residents of moderately dense urban areas were surveyed and…

Contrasting spatial patterns in active-fire and fire-suppressed Mediterranean climate old-growth mixed conifer forests

Treesearch

Danny L. Fry; Scott L. Stephens; Brandon M. Collins; Malcolm North; Ernesto Franco-Vizcaino; Samantha J. Gill

2014-01-01

In Mediterranean environments in western North America, historic fire regimes in frequent-fire conifer forests are highly variable both temporally and spatially. This complexity influenced forest structure and spatial patterns, but some of this diversity has been lost due to anthropogenic disruption of ecosystem processes, including fire. Information from reference...

The Wonderful World of the Musical

ERIC Educational Resources Information Center

Poliniak, Susan

2010-01-01

The challenges and joys of presenting high school and middle school musicals are myriad--and, due to the many variables involved, often unlike those of choral concerts, band concerts, or just about anything else that one may encounter as a teacher. With so many moving parts, it is easy to feel overwhelmed, especially if one is new to the game. In…

Global Contexts for Learning: Exploring the Relationship between Low-Context Online Learning and High-Context Learners

ERIC Educational Resources Information Center

Westbrook, Timothy Paul

2014-01-01

Current research on culture and distance education suggests that cultural variables influence student success online. When online courses are writing-based, they may provide easy information dissemination; however, the low-context medium may restrict the learning experience and class dynamic due to the lack of nonverbal communication. Students who…

Poverty Lines Based on Fuzzy Sets Theory and Its Application to Malaysian Data

ERIC Educational Resources Information Center

Abdullah, Lazim

2011-01-01

Defining the poverty line has been acknowledged as being highly variable by the majority of published literature. Despite long discussions and successes, poverty line has a number of problems due to its arbitrary nature. This paper proposes three measurements of poverty lines using membership functions based on fuzzy set theory. The three…

Solar Variability in the Context of Other Climate Forcing Mechanisms

NASA Technical Reports Server (NTRS)

Hansen, James E.

1999-01-01

I compare and contrast climate forcings due to solar variability with climate forcings due to other mechanisms of climate change, interpretation of the role of the sun in climate change depends upon climate sensitivity and upon the net forcing by other climate change mechanisms. Among the potential indirect climate forcings due to solar variability, only that due to solar cycle induced ozone changes has been well quantified. There is evidence that the sun has been a significant player in past climate change on decadal to century time scales, and that it has the potential to contribute to climate change in the 21st century.

High-Order Accurate Solutions to the Helmholtz Equation in the Presence of Boundary Singularities

DTIC Science & Technology

2015-03-31

FD scheme is only consistent for classical solutions of the PDE . For this reason, we implement the method of singularity subtraction as a means for...regularity due to the boundary conditions. This is because the FD scheme is only consistent for classical solutions of the PDE . For this reason, we...Introduction In the present work, we develop a high-order numerical method for solving linear elliptic PDEs with well-behaved variable coefficients on

Simulators for Mariner Training and Licensing. Phase 3: Investigation of Horizontal Field of View Requirements for Simulator-Based Training of Maritime Cadets,

DTIC Science & Technology

1981-12-01

addressing the "at-sea equivalence issue." * Request that the radar simulator-based training schools stress the importance of multiple navigational...potentially high cost simulator/training program variables, namely: e Target maneuverability Independent versus canned * Color visual scene Color versus... high wind conditions (40 knots). It appears that this may be due to insufficient understanding of: (1) responsiveness of the vessel to various rudder

A Transient Transit Signature Associated with the Young Star RIK-210

DOE Office of Scientific and Technical Information (OSTI.GOV)

David, Trevor J.; Hillenbrand, Lynne A.; Howard, Andrew W.

We find transient transit-like dimming events within the K2 time series photometry of the young star RIK-210 in the Upper Scorpius OB association. These dimming events are variable in depth, duration, and morphology. High spatial resolution imaging revealed that the star is single and radial velocity monitoring indicated that the dimming events cannot be due to an eclipsing stellar or brown dwarf companion. Archival and follow-up photometry suggest the dimming events are transient in nature. The variable morphology of the dimming events suggests they are not due to a single spherical body. The ingress of each dimming event is alwaysmore » shallower than egress, as one would expect for an orbiting body with a leading tail. The dimming events are periodic and synchronous with the stellar rotation. However, we argue it is unlikely the dimming events could be attributed to anything on the stellar surface based on the observed depths and durations. Variable obscuration by a protoplanetary disk is unlikely on the basis that the star is not actively accreting and lacks the infrared excess associated with an inner disk. Rather, we explore the possibilities that the dimming events are due to magnetospheric clouds, a transiting protoplanet surrounded by circumplanetary dust and debris, eccentric orbiting bodies undergoing periodic tidal disruption, or an extended field of dust or debris near the corotation radius.« less

Population biology of Avena : IX. Gene flow and neighborhood size in relation to microgeographic variation in Avena barbata.

PubMed

Rai, Kedar N; Jain, Subodh K

1982-06-01

Pollen and seed dispersal patterns were analyzed in both natural and experimental populations of Avena barbata. Localized estimates of gene flow rates and plant densities gave estimates of neighborhood size in the range of 40 to 400 plants; the estimates of mean rate and distance of gene flow seemed to vary widely due to variable wind direction, rodent activity, microsite heterogeneity, etc. The relative sizes of neighborhoods in several populations were correlated with the patchy distribution of different genotypes (scored for lemma color and leaf sheath hairiness) within short distances, but patch sizes had a wide range among different sites. Highly localized gene flow patterns seemed to account for the observed pattern of highly patchy variation even when the dispersal curves for both pollen and seed were platykurtic in many cases. Measures of the stability of patches in terms of their size, dispersion in space and genetic structure in time are needed in order to sort out the relative roles of founder effects, random drift (due to small neighborhood size), and highly localized selection. However, our observations suggest that many variables and stochastic processes are involved in such studies so as to allow only weak inference about the underlying role of natural selection, drift and factors of population regulatien.

Squeezing of particle distributions by expanding magnetic turbulence and space weather variability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ruffolo, D.; Seripienlert, A.; Tooprakai, P.

Among the space weather effects due to gradual solar storms, greatly enhanced high-energy ion fluxes contribute to radiation damage to satellites, spacecraft, and astronauts and dominate the hazards to air travelers, which motivates examination of the transport of high-energy solar ions to Earth's orbit. Ions of low kinetic energy (up to ∼2 MeV nucleon{sup –1}) from impulsive solar events exhibit abrupt changes due to filamentation of the magnetic connection from the Sun, indicating that anisotropic, field-aligned magnetic flux tubelike structures persist to Earth's orbit. By employing a corresponding spherical two-component model of Alfvénic (slab) and two-dimensional magnetic fluctuations to tracemore » simulated trajectories in the solar wind, we show that the distribution of high-energy (E ≥ 1 GeV) protons from gradual solar events is squeezed toward magnetic flux structures with a specific polarity because of the conical shape of the flux structures. Conical flux structures and the squeezing of energetic particle distributions should occur in any astrophysical wind or jet with expanding, magnetized, turbulent plasma. This transport phenomenon contributes to event-to-event variability in ground level enhancements of GeV-range ions from solar storms, presenting a fundamental uncertainty in space weather prediction.« less

Model-based Clustering of High-Dimensional Data in Astrophysics

NASA Astrophysics Data System (ADS)

Bouveyron, C.

2016-05-01

The nature of data in Astrophysics has changed, as in other scientific fields, in the past decades due to the increase of the measurement capabilities. As a consequence, data are nowadays frequently of high dimensionality and available in mass or stream. Model-based techniques for clustering are popular tools which are renowned for their probabilistic foundations and their flexibility. However, classical model-based techniques show a disappointing behavior in high-dimensional spaces which is mainly due to their dramatical over-parametrization. The recent developments in model-based classification overcome these drawbacks and allow to efficiently classify high-dimensional data, even in the "small n / large p" situation. This work presents a comprehensive review of these recent approaches, including regularization-based techniques, parsimonious modeling, subspace classification methods and classification methods based on variable selection. The use of these model-based methods is also illustrated on real-world classification problems in Astrophysics using R packages.

Temporal and spatial variation in pharmaceutical concentrations in an urban river system

USGS Publications Warehouse

Burns, Emily E.; Carter, Laura J.; Kolpin, Dana W.; Thomas-Oates, Jane; Boxall, Alistair B.A.

2018-01-01

Many studies have quantified pharmaceuticals in the environment, few however, have incorporated detailed temporal and spatial variability due to associated costs in terms of time and materials. Here, we target 33 physico-chemically diverse pharmaceuticals in a spatiotemporal exposure study into the occurrence of pharmaceuticals in the wastewater system and the Rivers Ouse and Foss (two diverse river systems) in the city of York, UK. Removal rates in two of the WWTPs sampled (a conventional activated sludge (CAS) and trickling filter plant) ranged from not eliminated (carbamazepine) to >99% (paracetamol). Data comparisons indicate that pharmaceutical exposures in river systems are highly variable regionally, in part due to variability in prescribing practices, hydrology, wastewater management, and urbanisation and that select annual median pharmaceutical concentrations observed in this study were higher than those previously observed in the European Union and Asia thus far. Significant spatial variability was found between all sites in both river systems, while seasonal variability was significant for 86% and 50% of compounds in the River Foss and Ouse, respectively. Seasonal variations in flow, in-stream attenuation, usage and septic effluent releases are suspected drivers behind some of the observed temporal exposure variability. When the data were used to evaluate a simple environmental exposure model for pharmaceuticals, mean ratios of predicted environmental concentrations (PECs), obtained using the model, to measured environmental concentrations (MECs) were 0.51 and 0.04 for the River Foss and River Ouse, respectively. Such PEC/MEC ratios indicate that the model underestimates actual concentrations in both river systems, but to a much greater extent in the larger River Ouse.

Biogeographical drivers of ragweed pollen concentrations in Europe

NASA Astrophysics Data System (ADS)

Matyasovszky, István; Makra, László; Tusnády, Gábor; Csépe, Zoltán; Nyúl, László G.; Chapman, Daniel S.; Sümeghy, Zoltán; Szűcs, Gábor; Páldy, Anna; Magyar, Donát; Mányoki, Gergely; Erostyák, János; Bodnár, Károly; Bergmann, Karl-Christian; Deák, Áron József; Thibaudon, Michel; Albertini, Roberto; Bonini, Maira; Šikoparija, Branko; Radišić, Predrag; Gehrig, Regula; Rybníček, Ondřej; Severova, Elena; Rodinkova, Victoria; Prikhodko, Alexander; Maleeva, Anna; Stjepanović, Barbara; Ianovici, Nicoleta; Berger, Uwe; Seliger, Andreja Kofol; Weryszko-Chmielewska, Elżbieta; Šaulienė, Ingrida; Shalaboda, Valentina; Yankova, Raina; Peternel, Renata; Ščevková, Jana; Bullock, James M.

2017-06-01

The drivers of spatial variation in ragweed pollen concentrations, contributing to severe allergic rhinitis and asthma, are poorly quantified. We analysed the spatiotemporal variability in 16-year (1995-2010) annual total (66 stations) and annual total (2010) (162 stations) ragweed pollen counts and 8 independent variables (start, end and duration of the ragweed pollen season, maximum daily and calendar day of the maximum daily ragweed pollen counts, last frost day in spring, first frost day in fall and duration of the frost-free period) for Europe (16 years, 1995-2010) as a function of geographical coordinates. Then annual total pollen counts, annual daily peak pollen counts and date of this peak were regressed against frost-related variables, daily mean temperatures and daily precipitation amounts. To achieve this, we assembled the largest ragweed pollen data set to date for Europe. The dependence of the annual total ragweed pollen counts and the eight independent variables against geographical coordinates clearly distinguishes the three highly infected areas: the Pannonian Plain, Western Lombardy and the Rhône-Alpes region. All the eight variables are sensitive to longitude through its temperature dependence. They are also sensitive to altitude, due to the progressively colder climate with increasing altitude. Both annual total pollen counts and the maximum daily pollen counts depend on the start and the duration of the ragweed pollen season. However, no significant changes were detected in either the eight independent variables as a function of increasing latitude. This is probably due to a mixed climate induced by strong geomorphological inhomogeneities in Europe.

Atlas based brain volumetry: How to distinguish regional volume changes due to biological or physiological effects from inherent noise of the methodology.

PubMed

Opfer, Roland; Suppa, Per; Kepp, Timo; Spies, Lothar; Schippling, Sven; Huppertz, Hans-Jürgen

2016-05-01

Fully-automated regional brain volumetry based on structural magnetic resonance imaging (MRI) plays an important role in quantitative neuroimaging. In clinical trials as well as in clinical routine multiple MRIs of individual patients at different time points need to be assessed longitudinally. Measures of inter- and intrascanner variability are crucial to understand the intrinsic variability of the method and to distinguish volume changes due to biological or physiological effects from inherent noise of the methodology. To measure regional brain volumes an atlas based volumetry (ABV) approach was deployed using a highly elastic registration framework and an anatomical atlas in a well-defined template space. We assessed inter- and intrascanner variability of the method in 51 cognitively normal subjects and 27 Alzheimer dementia (AD) patients from the Alzheimer's Disease Neuroimaging Initiative by studying volumetric results of repeated scans for 17 compartments and brain regions. Median percentage volume differences of scan-rescans from the same scanner ranged from 0.24% (whole brain parenchyma in healthy subjects) to 1.73% (occipital lobe white matter in AD), with generally higher differences in AD patients as compared to normal subjects (e.g., 1.01% vs. 0.78% for the hippocampus). Minimum percentage volume differences detectable with an error probability of 5% were in the one-digit percentage range for almost all structures investigated, with most of them being below 5%. Intrascanner variability was independent of magnetic field strength. The median interscanner variability was up to ten times higher than the intrascanner variability. Copyright © 2016 Elsevier Inc. All rights reserved.

Synthetic Spectral Ananlysis of the Nova-Like Variable KQ Mon

NASA Astrophysics Data System (ADS)

Wolfe, Aaron; Sion, E.

2011-01-01

KQ Mon is classified as a nova-like variable with an uncertain orbital period of 0.128 d. Optical spectra (Zwitter, T. & Munari, U.1994, A&AS, 107, 503) reveal no emission lines but strong Balmer absorption features. High speed flickering has been observed indicative of accretion. IUE spectra reveal deep absorption lines due to C III, C II, Si III, Si IV, C IV, He II but no P Cygni profiles indicative of outflow. Its classification in Ritter and Kolb (2006) as a UX UMa type nova-like is uncertain. We have carried out the first synthetic spectral analysis of the IUE archival spectra of KQ Mon with realistic accretion disk models with vertical structure and high gravity photosphere models. The results of our model atmosphere and model accretion disk analyses are presented. We discuss the properties that we have derived for KQ Mon and compare KQ Mon with other nova-like variables viewed at low inclination. This work was supported in part by NSF grant AST0807892 to Villanova University.

The rDNA ITS region in the lessepsian marine angiosperm Halophila stipulacea (Forssk.) Aschers. (Hydrocharitaceae): intragenomic variability and putative pseudogenic sequences.

PubMed

Ruggiero, Maria Valeria; Procaccini, Gabriele

2004-01-01

Halophila stipulacea is a dioecious marine angiosperm, widely distributed along the western coasts of the Indian Ocean and the Red Sea. This species is thought to be a Lessepsian immigrant that entered the Mediterranean Sea from the Red Sea after the opening of the Suez Canal (1869). Previous studies have revealed both high phenotypic and genetic variability in Halophila stipulacea populations from the western Mediterranean basin. In order to test the hypothesis of a Lessepsian introduction, we compare genetic polymorphism between putative native (Red Sea) and introduced (Mediterranean) populations through rDNA ITS region (ITS1-5.8S-ITS2) sequence analysis. A high degree of intraindividual variability of ITS sequences was found. Most of the intragenomic polymorphism was due to pseudogenic sequences, present in almost all individuals. Features of ITS functional sequences and pseudogenes are described. Possible causes for the lack of homogenization of ITS paralogues within individuals are discussed.

A brightening of the symbiotic variable SY Muscae

NASA Technical Reports Server (NTRS)

Michalitsianos, A. G.; Feibelman, W. A.; Kafatos, M.; Wallerstein, G.

1982-01-01

The symbiotic variable SY Muscae has been observed with IUE in September 1980 and June 1981 and in the photographic region in May 1981. The entire ultraviolet spectrum brightened between September and June by about a factor of 5. The spectrum shows high excitation including emission from N v and high electron density, about 10-billion per cu cm as determined from various line ratios in the ultraviolet. The optical spectrum is dominated by permitted lines; even forbidden O III is very weak again indicating high density in the ionized region. The increase in ultraviolet continuum and line emission may be due to enhanced mass transfer from the cool star whose period is 623d and whose maximum was predicted to occur very close to the time of the June 1981 observations. Alternatively the hot star and much of the emitting gas could have been in eclipse in September 1980.

VizieR Online Data Catalog: RR Lyrae in SDSS Stripe 82 (Suveges+, 2012)

NASA Astrophysics Data System (ADS)

Suveges, M.; Sesar, B.; Varadi, M.; Mowlavi, N.; Becker, A. C.; Ivezic, Z.; Beck, M.; Nienartowicz, K.; Rimoldini, L.; Dubath, P.; Bartholdi, P.; Eyer, L.

2013-05-01

We propose a robust principal component analysis framework for the exploitation of multiband photometric measurements in large surveys. Period search results are improved using the time-series of the first principal component due to its optimized signal-to-noise ratio. The presence of correlated excess variations in the multivariate time-series enables the detection of weaker variability. Furthermore, the direction of the largest variance differs for certain types of variable stars. This can be used as an efficient attribute for classification. The application of the method to a subsample of Sloan Digital Sky Survey Stripe 82 data yielded 132 high-amplitude delta Scuti variables. We also found 129 new RR Lyrae variables, complementary to the catalogue of Sesar et al., extending the halo area mapped by Stripe 82 RR Lyrae stars towards the Galactic bulge. The sample also comprises 25 multiperiodic or Blazhko RR Lyrae stars. (8 data files).

Local oceanographic variability influences the performance of juvenile abalone under climate change.

PubMed

Boch, C A; Micheli, F; AlNajjar, M; Monismith, S G; Beers, J M; Bonilla, J C; Espinoza, A M; Vazquez-Vera, L; Woodson, C B

2018-04-03

Climate change is causing warming, deoxygenation, and acidification of the global ocean. However, manifestation of climate change may vary at local scales due to oceanographic conditions. Variation in stressors, such as high temperature and low oxygen, at local scales may lead to variable biological responses and spatial refuges from climate impacts. We conducted outplant experiments at two locations separated by ~2.5 km and two sites at each location separated by ~200 m in the nearshore of Isla Natividad, Mexico to assess how local ocean conditions (warming and hypoxia) may affect juvenile abalone performance. Here, we show that abalone growth and mortality mapped to variability in stress exposure across sites and locations. These insights indicate that management decisions aimed at maintaining and recovering valuable marine species in the face of climate change need to be informed by local variability in environmental conditions.

Ionospheric responses during equinox and solstice periods over Turkey

NASA Astrophysics Data System (ADS)

Karatay, Secil; Cinar, Ali; Arikan, Feza

2017-11-01

Ionospheric electron density is the determining variable for investigation of the spatial and temporal variations in the ionosphere. Total Electron Content (TEC) is the integral of the electron density along a ray path that indicates the total variability through the ionosphere. Global Positioning System (GPS) recordings can be utilized to estimate the TEC, thus GPS proves itself as a useful tool in monitoring the total variability of electron distribution within the ionosphere. This study focuses on the analysis of the variations of ionosphere over Turkey that can be grouped into anomalies during equinox and solstice periods using TEC estimates obtained by a regional GPS network. It is observed that noon time depletions in TEC distributions predominantly occur in winter for minimum Sun Spots Numbers (SSN) in the central regions of Turkey which also exhibit high variability due to midlatitude winter anomaly. TEC values and ionospheric variations at solstice periods demonstrate significant enhancements compared to those at equinox periods.

Variability, trends, and drivers of regional fluctuations in Australian fire activity

NASA Astrophysics Data System (ADS)

Earl, Nick; Simmonds, Ian

2017-07-01

Throughout the world fire regimes are determined by climate, vegetation, and anthropogenic factors, and they have great spatial and temporal variability. The availability of high-quality satellite data has revolutionized fire monitoring, allowing for a more consistent and comprehensive evaluation of temporal and spatial patterns. Here we utilize a satellite based "active fire" (AF) product to statistically analyze 2001-2015 variability and trends in Australian fire activity and link this to precipitation and large-scale atmospheric structures (namely, the El Niño-Southern Oscillation (ENSO) and the Indian Ocean Dipole (IOD)) known to have potential for predicting fire activity in different regions. It is found that Australian fire activity is decreasing (during summer (December-February)) or stable, with high temporal and spatial variability. Eastern New South Wales (NSW) has the strongest decreasing trend (to the 1% confidence level), especially during the winter (JJA) season. Other significantly decreasing areas are Victoria/NSW, Tasmania, and South-east Queensland. These decreasing fire regions are relatively highly populated, so we suggest that the declining trends are due to improved fire management, reducing the size and duration of bush fires. Almost half of all Australian AFs occur during spring (September-November). We show that there is considerable potential throughout Australia for a skillful forecast for future season fire activity based on current and previous precipitation activity, ENSO phase, and to a lesser degree, the IOD phase. This is highly variable, depending on location, e.g., the IOD phase is for more indicative of fire activity in southwest Western Australia than for Queensland.

Airborne black carbon concentrations over an urban region in western India-temporal variability, effects of meteorology, and source regions.

PubMed

Bapna, Mukund; Sunder Raman, Ramya; Ramachandran, S; Rajesh, T A

2013-03-01

This study characterizes over 5 years of high time resolution (5 min), airborne black carbon (BC) concentrations (July 2003 to December 2008) measured over Ahmedabad, an urban region in western India. The data were used to obtain different time averages of BC concentrations, and these averages were then used to assess the diurnal, seasonal, and annual variability of BC over the study region. Assessment of diurnal variations revealed a strong association between BC concentrations and vehicular traffic. Peaks in BC concentration were co-incident with the morning (0730 to 0830, LST) and late evening (1930 to 2030, LST) rush hour traffic. Additionally, diurnal variability in BC concentrations during major festivals (Diwali and Dushera during the months of October/November) revealed an increase in BC concentrations due to fireworks displays. Maximum half hourly BC concentrations during the festival days were as high as 79.8 μg m(-3). However, the high concentrations rapidly decayed suggesting that local meteorology during the festive season was favorable for aerosol dispersion. A multiple linear regression (MLR) model with BC as the dependent variable and meteorological parameters as independent variables was fitted. The variability in temperature, humidity, wind speed, and wind direction accounted for about 49% of the variability in measured BC concentrations. Conditional probability function (CPF) analysis was used to identify the geographical location of local source regions contributing to the effective BC measured (at 880 nm) at the receptor site. The east north-east (ENE) direction to the receptor was identified as a major source region. National highway (NH8) and two coal-fired thermal power stations (at Gandhinagar and Sabarmati) were located in the identified direction, suggesting that local traffic and power plant emissions were likely contributors to the measured BC.

Variable Lifting Index (VLI)

PubMed Central

Waters, Thomas; Occhipinti, Enrico; Colombini, Daniela; Alvarez-Casado, Enrique; Fox, Robert

2015-01-01

Objective: We seek to develop a new approach for analyzing the physical demands of highly variable lifting tasks through an adaptation of the Revised NIOSH (National Institute for Occupational Safety and Health) Lifting Equation (RNLE) into a Variable Lifting Index (VLI). Background: There are many jobs that contain individual lifts that vary from lift to lift due to the task requirements. The NIOSH Lifting Equation is not suitable in its present form to analyze variable lifting tasks. Method: In extending the prior work on the VLI, two procedures are presented to allow users to analyze variable lifting tasks. One approach involves the sampling of lifting tasks performed by a worker over a shift and the calculation of the Frequency Independent Lift Index (FILI) for each sampled lift and the aggregation of the FILI values into six categories. The Composite Lift Index (CLI) equation is used with lifting index (LI) category frequency data to calculate the VLI. The second approach employs a detailed systematic collection of lifting task data from production and/or organizational sources. The data are organized into simplified task parameter categories and further aggregated into six FILI categories, which also use the CLI equation to calculate the VLI. Results: The two procedures will allow practitioners to systematically employ the VLI method to a variety of work situations where highly variable lifting tasks are performed. Conclusions: The scientific basis for the VLI procedure is similar to that for the CLI originally presented by NIOSH; however, the VLI method remains to be validated. Application: The VLI method allows an analyst to assess highly variable manual lifting jobs in which the task characteristics vary from lift to lift during a shift. PMID:26646300

Estimating the effects of land use at different scales on high ecological status in Irish rivers.

PubMed

Roberts, William M; Fealy, Reamonn M; Doody, Donnacha G; Jordan, Phil; Daly, Karen

2016-12-01

High ecological status at river sites is an indicator of minimal disturbance from anthropogenic activities and the presence of ecologically important species and communities. However, a lack of clarity on what factors cause sites to lose high ecological status is limiting the ability to maintain the quality of these sites. Examination of ecological status records at 508 high status river sites throughout the Republic of Ireland revealed that 337 had fallen below high status at some point between 2001 and 2012 due to changes in invertebrate communities. A geographical information system was used to characterise land use and environmental variables in the catchment, riparian and reach areas upstream of the sites. The relationships between these variables at the three spatial scales and whether or not river sites had maintained high ecological status were then estimated by multiple logistic regression and propensity modelling. The results indicated that grassland at either catchment or riparian scales had a greater negative impact on high ecological status than at the reach scale. This effect appeared to be strongest for upland, steeply sloping rivers that are subject to high rainfall, possibly due to the presence of sensitive biota and/or a greater potential for erosion. These results highlighted the need for better management of grassland upstream of the high status sites, with a focus on river alterations and critical source areas of nutrients, sediments and pesticides that are hydrologically connected to the river. Sustainable management practices and land use planning in those areas will need to be considered carefully if the aim of maintaining high ecological status at river sites is to be achieved. Copyright © 2016 Elsevier B.V. All rights reserved.

Influence of variable selection on partial least squares discriminant analysis models for explosive residue classification

NASA Astrophysics Data System (ADS)

De Lucia, Frank C., Jr.; Gottfried, Jennifer L.

2011-02-01

Using a series of thirteen organic materials that includes novel high-nitrogen energetic materials, conventional organic military explosives, and benign organic materials, we have demonstrated the importance of variable selection for maximizing residue discrimination with partial least squares discriminant analysis (PLS-DA). We built several PLS-DA models using different variable sets based on laser induced breakdown spectroscopy (LIBS) spectra of the organic residues on an aluminum substrate under an argon atmosphere. The model classification results for each sample are presented and the influence of the variables on these results is discussed. We found that using the whole spectra as the data input for the PLS-DA model gave the best results. However, variables due to the surrounding atmosphere and the substrate contribute to discrimination when the whole spectra are used, indicating this may not be the most robust model. Further iterative testing with additional validation data sets is necessary to determine the most robust model.

Broadband short term X-ray variability of the quasar PDS 456

NASA Astrophysics Data System (ADS)

Matzeu, G. A.; Reeves, J. N.; Nardini, E.; Braito, V.; Costa, M. T.; Tombesi, F.; Gofford, J.

2016-05-01

We present a detailed analysis of a recent 500 ks net exposure Suzaku observation, carried out in 2013, of the nearby (z=0.184) luminous (L_bol˜1047 erg s-1) quasar PDS 456 in which the X-ray flux was unusually low. The short term X-ray spectral variability has been interpreted in terms of variable absorption and/or intrinsic continuum changes. In the former scenario, the spectral variability is due to variable covering factors of two regions of partially covering absorbers. We find that these absorbers are characterised by an outflow velocity comparable to that of the highly ionised wind, i.e. ˜ 0.25 c, at the 99.9% (3.26σ) confidence level. This suggests that the partially absorbing clouds may be the denser clumpy part of the inhomogeneous wind. Following an obscuration event we obtained a direct estimate of the size of the X-ray emitting region, to be not larger than 20 R_g in PDS 456.

Solar forcing synchronizes decadal North Atlantic climate variability.

PubMed

Thiéblemont, Rémi; Matthes, Katja; Omrani, Nour-Eddine; Kodera, Kunihiko; Hansen, Felicitas

2015-09-15

Quasi-decadal variability in solar irradiance has been suggested to exert a substantial effect on Earth's regional climate. In the North Atlantic sector, the 11-year solar signal has been proposed to project onto a pattern resembling the North Atlantic Oscillation (NAO), with a lag of a few years due to ocean-atmosphere interactions. The solar/NAO relationship is, however, highly misrepresented in climate model simulations with realistic observed forcings. In addition, its detection is particularly complicated since NAO quasi-decadal fluctuations can be intrinsically generated by the coupled ocean-atmosphere system. Here we compare two multi-decadal ocean-atmosphere chemistry-climate simulations with and without solar forcing variability. While the experiment including solar variability simulates a 1-2-year lagged solar/NAO relationship, comparison of both experiments suggests that the 11-year solar cycle synchronizes quasi-decadal NAO variability intrinsic to the model. The synchronization is consistent with the downward propagation of the solar signal from the stratosphere to the surface.

Assimilating bio-optical glider data during a phytoplankton bloom in the southern Ross Sea

NASA Astrophysics Data System (ADS)

Kaufman, Daniel E.; Friedrichs, Marjorie A. M.; Hemmings, John C. P.; Smith, Walker O., Jr.

2018-01-01

The Ross Sea is a region characterized by high primary productivity in comparison to other Antarctic coastal regions, and its productivity is marked by considerable variability both spatially (1-50 km) and temporally (days to weeks). This variability presents a challenge for inferring phytoplankton dynamics from observations that are limited in time or space, which is often the case due to logistical limitations of sampling. To better understand the spatiotemporal variability in Ross Sea phytoplankton dynamics and to determine how restricted sampling may skew dynamical interpretations, high-resolution bio-optical glider measurements were assimilated into a one-dimensional biogeochemical model adapted for the Ross Sea. The assimilation of data from the entire glider track using the micro-genetic and local search algorithms in the Marine Model Optimization Testbed improves the model-data fit by ˜ 50 %, generating rates of integrated primary production of 104 g C m-2 yr-1 and export at 200 m of 27 g C m-2 yr-1. Assimilating glider data from three different latitudinal bands and three different longitudinal bands results in minimal changes to the simulations, improves the model-data fit with respect to unassimilated data by ˜ 35 %, and confirms that analyzing these glider observations as a time series via a one-dimensional model is reasonable on these scales. Whereas assimilating the full glider data set produces well-constrained simulations, assimilating subsampled glider data at a frequency consistent with cruise-based sampling results in a wide range of primary production and export estimates. These estimates depend strongly on the timing of the assimilated observations, due to the presence of high mesoscale variability in this region. Assimilating surface glider data subsampled at a frequency consistent with available satellite-derived data results in 40 % lower carbon export, primarily resulting from optimized rates generating more slowly sinking diatoms. This analysis highlights the need for the strategic consideration of the impacts of data frequency, duration, and coverage when combining observations with biogeochemical modeling in regions with strong mesoscale variability.

Allozyme diversity and morphometrics of Melocactus paucispinus (Cactaceae) and evidence for hybridization with M. concinnus in the Chapada Diamantina, North-eastern Brazil.

PubMed

Lambert, Sabrina Mota; Borba, Eduardo Leite; Machado, Marlon Câmara; Da Silva Andrade, Sónia Cristina

2006-03-01

Melocacatus paucispinus (Cactaceae) is endemic to the state of Bahia, Brazil, and due to its rarity and desirability to collectors it has been considered threatened with extinction. This species is usually sympatric and inter-fertile with M. concinnus, and morphological evidence for hybridization between them is present in some populations. Levels of genetic and morphological variation and sub-structuring in populations of these species were assessed and an attempt was made to verify the occurrence of natural hybridization between them. Genetic variability was surveyed using allozymes (12 loci) and morphological variability using multivariate morphometric analyses (17 vegetative characters) in ten populations of M. paucispinus and three of M. concinnus occurring in the Chapada Diamantina, Bahia. Genetic variability was low in both species (P = 0.0-33.3, A = 1.0-1.6, H(e) = 0.000-0.123 in M. paucispinus; P = 0.0-25.0, A = 1.0-1.4, H(e) = 0.000-0.104 in M. concinnus). Deficit of heterozygotes within the populations was detected in both species, with high values of F(IS) (0.732 and 0.901 in M. paucispinus and M. concinnus, respectively). Evidence of hybridization was detected by the relative allele frequency in the two diaphorase loci. High levels of genetic (F(ST) = 0.504 in M. paucispinus and 0.349 in M. concinnus) and morphological (A = 0.20 in M. paucispinus and 0.17 in M. concinnus) structuring among populations were found. The Melocactus spp. displayed levels of genetic variability lower than the values reported for other cactus species. The evidence indicates the occurrence of introgression in both species at two sites. The high F(ST) values cannot be explained by geographical substructuring, but are consistent with hybridization. Conversely, morphological differentiation in M. paucispinus, but not in M. concinnus, is probably due to isolation by distance.

High-frequency and meso-scale winter sea-ice variability in the Southern Ocean in a high-resolution global ocean model

NASA Astrophysics Data System (ADS)

Stössel, Achim; von Storch, Jin-Song; Notz, Dirk; Haak, Helmuth; Gerdes, Rüdiger

2018-03-01

This study is on high-frequency temporal variability (HFV) and meso-scale spatial variability (MSV) of winter sea-ice drift in the Southern Ocean simulated with a global high-resolution (0.1°) sea ice-ocean model. Hourly model output is used to distinguish MSV characteristics via patterns of mean kinetic energy (MKE) and turbulent kinetic energy (TKE) of ice drift, surface currents, and wind stress, and HFV characteristics via time series of raw variables and correlations. We find that (1) along the ice edge, the MSV of ice drift coincides with that of surface currents, in particular such due to ocean eddies; (2) along the coast, the MKE of ice drift is substantially larger than its TKE and coincides with the MKE of wind stress; (3) in the interior of the ice pack, the TKE of ice drift is larger than its MKE, mostly following the TKE pattern of wind stress; (4) the HFV of ice drift is dominated by weather events, and, in the absence of tidal currents, locally and to a much smaller degree by inertial oscillations; (5) along the ice edge, the curl of the ice drift is highly correlated with that of surface currents, mostly reflecting the impact of ocean eddies. Where ocean eddies occur and the ice is relatively thin, ice velocity is characterized by enhanced relative vorticity, largely matching that of surface currents. Along the ice edge, ocean eddies produce distinct ice filaments, the realism of which is largely confirmed by high-resolution satellite passive-microwave data.

Natural wind variability triggered drop in German redispatch volume and costs from 2015 to 2016

PubMed Central

Reyers, Mark; Märker, Carolin; Witthaut, Dirk

2018-01-01

Avoiding dangerous climate change necessitates the decarbonization of electricity systems within the next few decades. In Germany, this decarbonization is based on an increased exploitation of variable renewable electricity sources such as wind and solar power. While system security has remained constantly high, the integration of renewables causes additional costs. In 2015, the costs of grid management saw an all time high of about € 1 billion. Despite the addition of renewable capacity, these costs dropped substantially in 2016. We thus investigate the effect of natural climate variability on grid management costs in this study. We show that the decline is triggered by natural wind variability focusing on redispatch as a main cost driver. In particular, we find that 2016 was a weak year in terms of wind generation averages and the occurrence of westerly circulation weather types. Moreover, we show that a simple model based on the wind generation time series is skillful in detecting redispatch events on timescales of weeks and beyond. As a consequence, alterations in annual redispatch costs in the order of hundreds of millions of euros need to be understood and communicated as a normal feature of the current system due to natural wind variability. PMID:29329349

Formation of fold and thrust belts on Venus due to horizontal shortening of a laterally heterogeneous lithosphere

NASA Technical Reports Server (NTRS)

Zuber, M. T.; Parmentier, E. M.; Neumann, G. A.

1994-01-01

An outstanding question relevant to understanding the tectonics of Venus is the mechanism of formation of fold and thrust belts, such as the mountain belts that surround Lakshmi Planum in western Ishtar Terra. These structures are typically long (hundreds of km) and narrow (many tens of km), and are often located at the margins of relatively high (km-scale) topographic rises. Previous studies have attempted to explain fold and thrust belts in various areas of Venus in the context of viscous and brittle wedge theory. However, while wedge theory can explain the change in elevation from the rise to the adjacent lowland, it fails to account for a fundamental aspect of the deformation, i.e., the topographic high at the edge of the rise. In this study we quantitatively explore the hypothesis that fold and thrust belt morphology on Venus can alternatively be explained by horizontal shortening of a lithosphere that is laterally heterogeneous, due either to a change in thickness of the lithosphere or the crust. Lateral heterogeneities in lithosphere structure may arise in response to thermal thinning or extensive faulting, while variations in crustal thickness may arise due to either spatially variable melting of mantle material or by horizontal shortening of the crust. In a variable thickness lithosphere or crust that is horizontally shortened, deformation will tend to localize in the vicinity of thickness heterogeneity, resulting in a higher component of dynamic topography there as compared to elsewhere in the shortening lithosphere. This mechanism may thus provide a simple explanation for the topographic high at the edge of the rise.

Formation of fold and thrust belts on Venus due to horizontal shortening of a laterally heterogeneous lithosphere

NASA Astrophysics Data System (ADS)

Zuber, M. T.; Parmentier, E. M.; Neumann, G. A.

1994-03-01

An outstanding question relevant to understanding the tectonics of Venus is the mechanism of formation of fold and thrust belts, such as the mountain belts that surround Lakshmi Planum in western Ishtar Terra. These structures are typically long (hundreds of km) and narrow (many tens of km), and are often located at the margins of relatively high (km-scale) topographic rises. Previous studies have attempted to explain fold and thrust belts in various areas of Venus in the context of viscous and brittle wedge theory. However, while wedge theory can explain the change in elevation from the rise to the adjacent lowland, it fails to account for a fundamental aspect of the deformation, i.e., the topographic high at the edge of the rise. In this study we quantitatively explore the hypothesis that fold and thrust belt morphology on Venus can alternatively be explained by horizontal shortening of a lithosphere that is laterally heterogeneous, due either to a change in thickness of the lithosphere or the crust. Lateral heterogeneities in lithosphere structure may arise in response to thermal thinning or extensive faulting, while variations in crustal thickness may arise due to either spatially variable melting of mantle material or by horizontal shortening of the crust. In a variable thickness lithosphere or crust that is horizontally shortened, deformation will tend to localize in the vicinity of thickness heterogeneity, resulting in a higher component of dynamic topography there as compared to elsewhere in the shortening lithosphere. This mechanism may thus provide a simple explanation for the topographic high at the edge of the rise.

Connecting Variability and Metals in White Dwarfs

NASA Astrophysics Data System (ADS)

Kilic, Mukremin

2016-10-01

The Kepler and K2 missions have revealed that about half of the observed white dwarfs with sufficient signal-to-noise ratio light curves have low-level photometric variations at hour to day timescales. Potential explanations for the observed variability include the relativistic beaming effect, ellipsodial variations, eclipses, and reflection off of giant planets in close orbits. However, these are all rare events. Roughly 10% of white dwarfs are magnetic, and magnetic fields can explain part of this puzzle. However, the high incidence (50%) of variability is currently unexplained. HST COS spectroscopy of nearby white dwarfs show that about half of them have metals on their surface. Hence, we propose that the observed variability is due to the rotation of the star coupled with an inhomogeneous surface distribution of accreted metals. We have recently discovered an ideal system to test this hypothesis. J1529 is an apparently non-magnetic white dwarf that shows 5.9% photometric dips in the optical every 38 min. We propose to obtain COS TIME-TAG spectroscopy of J1529 over 4 orbits to search for surface abundance differences throughout the orbit and look for the flux redistribution effect in the optical. These observations will confirm or rule out the idea that inhomogeneous metal accretion on white dwarfs can explain the high incidence of variability. We predict that the LSST will identify 100,000 variable white dwarfs. Hence, understanding the source of variability in white dwarfs has implications for the current and future transient surveys.

Methane Seeps in the Gulf of Mexico: repeat acoustic surveying shows highly temporally and spatially variable venting

NASA Astrophysics Data System (ADS)

Beaumont, B. C.; Raineault, N.

2016-02-01

Scientists have recognized that natural seeps account for a large amount of methane emissions. Despite their widespread occurrence in areas like the Gulf of Mexico, little is known about the temporal variability and site-scale spatial variability of venting over time. We used repeat acoustic surveys to compare multiple days of seep activity and determine the changes in the locus of methane emission and plume height. The Sleeping Dragon site was surveyed with an EM302 multibeam sonar on three consecutive days in 2014 and 4 days within one week in 2015. The data revealed three distinctive plume regions. The locus of venting varied by 10-60 meters at each site. The plume that exhibited the least spatial variability in venting, was also the most temporally variable. This seep was present in one-third of survey dates in 2014 and three quarters of survey dates in 2015, showing high day-to-day variability. The plume height was very consistent for this plume, whereas the other plumes were more consistent temporally, but varied in maximum plume height detection by 25-85 m. The single locus of emission at the site that had high day-to-day variability may be due to a single conduit for methane release, which is sometimes closed off by carbonate or clathrate hydrate formation. In addition to day-to-day temporal variability, the locus of emission at one site was observed to shift from a point-source in 2014 to a diffuse source in 2015 at a nearby location. ROV observations showed that one of the seep sites that closed off temporarily, experienced an explosive breakthrough of gas, releasing confined methane and blowing out rock. The mechanism that causes on/off behavior of certain plumes, combined with the spatial variability of the locus of methane release shown in this study may point to carbonate or hydrate formation in the seep plumbing system and should be further investigated.

Fine-scale habitat modeling of a top marine predator: do prey data improve predictive capacity?

PubMed

Torres, Leigh G; Read, Andrew J; Halpin, Patrick

2008-10-01

Predators and prey assort themselves relative to each other, the availability of resources and refuges, and the temporal and spatial scale of their interaction. Predictive models of predator distributions often rely on these relationships by incorporating data on environmental variability and prey availability to determine predator habitat selection patterns. This approach to predictive modeling holds true in marine systems where observations of predators are logistically difficult, emphasizing the need for accurate models. In this paper, we ask whether including prey distribution data in fine-scale predictive models of bottlenose dolphin (Tursiops truncatus) habitat selection in Florida Bay, Florida, U.S.A., improves predictive capacity. Environmental characteristics are often used as predictor variables in habitat models of top marine predators with the assumption that they act as proxies of prey distribution. We examine the validity of this assumption by comparing the response of dolphin distribution and fish catch rates to the same environmental variables. Next, the predictive capacities of four models, with and without prey distribution data, are tested to determine whether dolphin habitat selection can be predicted without recourse to describing the distribution of their prey. The final analysis determines the accuracy of predictive maps of dolphin distribution produced by modeling areas of high fish catch based on significant environmental characteristics. We use spatial analysis and independent data sets to train and test the models. Our results indicate that, due to high habitat heterogeneity and the spatial variability of prey patches, fine-scale models of dolphin habitat selection in coastal habitats will be more successful if environmental variables are used as predictor variables of predator distributions rather than relying on prey data as explanatory variables. However, predictive modeling of prey distribution as the response variable based on environmental variability did produce high predictive performance of dolphin habitat selection, particularly foraging habitat.

Lactational Stage of Pasteurized Human Donor Milk Contributes to Nutrient Limitations for Infants

PubMed Central

Valentine, Christina J.; Morrow, Georgia; Reisinger, Amanda; Dingess, Kelly A.; Morrow, Ardythe L.; Rogers, Lynette K.

2017-01-01

Background. Mother’s own milk is the first choice for feeding preterm infants, but when not available, pasteurized human donor milk (PDM) is often used. Infants fed PDM have difficulties maintaining appropriate growth velocities. To assess the most basic elements of nutrition, we tested the hypotheses that fatty acid and amino acid composition of PDM is highly variable and standard pooling practices attenuate variability; however, total nutrients may be limiting without supplementation due to late lactational stage of the milk. Methods. A prospective cross-sectional sampling of milk was obtained from five donor milk banks located in Ohio, Michigan, Colorado, Texas-Ft Worth, and California. Milk samples were collected after Institutional Review Board (#07-0035) approval and informed consent. Fatty acid and amino acid contents were measured in milk from individual donors and donor pools (pooled per Human Milk Banking Association of North America guidelines). Statistical comparisons were performed using Kruskal–Wallis, Spearman’s, or Multivariate Regression analyses with center as the fixed factor and lactational stage as co-variate. Results. Ten of the fourteen fatty acids and seventeen of the nineteen amino acids analyzed differed across Banks in the individual milk samples. Pooling minimized these differences in amino acid and fatty acid contents. Concentrations of lysine and docosahexaenoic acid (DHA) were not different across Banks, but concentrations were low compared to recommended levels. Conclusions. Individual donor milk fatty acid and amino acid contents are highly variable. Standardized pooling practice reduces this variability. Lysine and DHA concentrations were consistently low across geographic regions in North America due to lactational stage of the milk, and thus not adequately addressed by pooling. Targeted supplementation is needed to optimize PDM, especially for the preterm or volume restricted infant. PMID:28335478

Electrowetting Variable Optics for Visible and Infrared Applications

NASA Astrophysics Data System (ADS)

Watson, Alexander Maxwell

Miniaturized variable optical devices are important for the fields of medical technology, optical communication, and consumer imaging devices. Areas ranging from endoscopy and optogenetics to atomic clocks and imaging all benefit from versatile optical systems. These applications all require precise and rapid control of imaging focal depth and lateral scanning. Electrowetting variable optics is one emergent technology that has the capability to provide focus tuning, beam steering, and even phase modulation in a small and robust package which requires no moving parts. Furthermore, electrowetting based devices there are attractive due to their transmissive nature, polarization insensitivity, low insertion loss, low electrical power requirements, and high optical quality. These features mean that electrowetting adaptive optical components are an attractive solution, compared with MEMS and liquid crystal optical components. Electrowetting is a technique that enables control of the shape of a liquid droplet with applied voltage. A conductive droplet on a dielectric surface alters its contact angle due to charges that build up between an underlying electrode and the surface of the droplet. This effect can be used to tune the curvature and tilt of liquids within cavities. The liquid boundary creates a high quality surface to use for lensing or steering applications. This thesis will focus on the development of electrowetting based lenses and prisms and applications in imaging for both visible and infrared wavelengths. Within this dissertation is the first demonstration of electrowetting lenses for phase control, as well as the investigation of non-aqueous electrowetting lens liquids for electrowetting lenses operation in the infrared. Key considerations that affect the performance and reliability are dielectric material and thickness, liquid selection and source of ionic conduction. The optical devices presented herein utilize judicious selection of dielectric material and electrowetting liquids to enable low voltage variable optics and demonstrate applications in microscopy and microendoscopy.

Quantifying the variability in stiffness and damping of an automotive vehicle's trim-structure mounts

NASA Astrophysics Data System (ADS)

Abolfathi, Ali; O'Boy, Dan J.; Walsh, Stephen J.; Dowsett, Amy; Fisher, Stephen A.

2016-09-01

Small plastic clips are used in large numbers in automotive vehicles to connect interior trims to vehicle structures. The variability in their properties can contribute to the overall variability in noise and vibration response of the vehicle. The variability arises due to their material and manufacturing tolerances and more importantly due to the boundary condition. To measure their stiffness and damping, a simple experimental rig is used where a mass is supported by the clip which is modelled as a single degree of freedom system. The rig is designed in a way that it simulates the boundary condition as those of the real vehicle. The variability in clip and also due to the boundary condition at the structure side is first examined which is 7% for stiffness and 8% for damping. To simulate the connection of the trim side, a mount is built using a 3D printer. Rattling occurs in the response of the clips with loose connections, however by preloading the mount the effective stiffness increases and the rattling is eliminated. The variability due to the boundary condition at the trim side was as large as 40% for stiffness and 52% for damping.

Benthic iron cycling in a high-oxygen environment: Implications for interpreting the Archean sedimentary iron isotope record.

PubMed

McCoy, V E; Asael, D; Planavsky, N

2017-09-01

The most notable trend in the sedimentary iron isotope record is a shift at the end of the Archean from highly variable δ 56 Fe values with large negative excursions to less variable δ 56 Fe values with more limited negative values. The mechanistic explanation behind this trend has been extensively debated, with two main competing hypotheses: (i) a shift in marine redox conditions and the transition to quantitative iron oxidation; and (ii) a decrease in the signature of microbial iron reduction in the sedimentary record because of increased bacterial sulfate reduction (BSR). Here, we provide new insights into this debate and attempt to assess these two hypotheses by analyzing the iron isotope composition of siderite concretions from the Carboniferous Mazon Creek fossil site. These concretions precipitated in an environment with water column oxygenation, extensive sediment pile dissimilatory iron reduction (DIR) but limited bacterial sulfate reduction (BSR). Most of the concretions have slightly positive iron isotope values, with a mean of 0.15‰ and limited iron isotope variability compared to the Archean sedimentary record. This limited variability in an environment with high DIR and low BSR suggests that these conditions alone are insufficient to explain Archean iron isotope compositions. Therefore, these results support the idea that the unusually variable and negative iron isotope values in the Archean are due to dissimilatory iron reduction (DIR) coupled with extensive water column iron cycling. © 2017 John Wiley & Sons Ltd.

Incorporating wind availability into land use regression modelling of air quality in mountainous high-density urban environment.

PubMed

Shi, Yuan; Lau, Kevin Ka-Lun; Ng, Edward

2017-08-01

Urban air quality serves as an important function of the quality of urban life. Land use regression (LUR) modelling of air quality is essential for conducting health impacts assessment but more challenging in mountainous high-density urban scenario due to the complexities of the urban environment. In this study, a total of 21 LUR models are developed for seven kinds of air pollutants (gaseous air pollutants CO, NO 2 , NO x , O 3 , SO 2 and particulate air pollutants PM 2.5 , PM 10 ) with reference to three different time periods (summertime, wintertime and annual average of 5-year long-term hourly monitoring data from local air quality monitoring network) in Hong Kong. Under the mountainous high-density urban scenario, we improved the traditional LUR modelling method by incorporating wind availability information into LUR modelling based on surface geomorphometrical analysis. As a result, 269 independent variables were examined to develop the LUR models by using the "ADDRESS" independent variable selection method and stepwise multiple linear regression (MLR). Cross validation has been performed for each resultant model. The results show that wind-related variables are included in most of the resultant models as statistically significant independent variables. Compared with the traditional method, a maximum increase of 20% was achieved in the prediction performance of annual averaged NO 2 concentration level by incorporating wind-related variables into LUR model development. Copyright © 2017 Elsevier Inc. All rights reserved.

Detection of Nitrogen Content in Rubber Leaves Using Near-Infrared (NIR) Spectroscopy with Correlation-Based Successive Projections Algorithm (SPA).

PubMed

Tang, Rongnian; Chen, Xupeng; Li, Chuang

2018-05-01

Near-infrared spectroscopy is an efficient, low-cost technology that has potential as an accurate method in detecting the nitrogen content of natural rubber leaves. Successive projections algorithm (SPA) is a widely used variable selection method for multivariate calibration, which uses projection operations to select a variable subset with minimum multi-collinearity. However, due to the fluctuation of correlation between variables, high collinearity may still exist in non-adjacent variables of subset obtained by basic SPA. Based on analysis to the correlation matrix of the spectra data, this paper proposed a correlation-based SPA (CB-SPA) to apply the successive projections algorithm in regions with consistent correlation. The result shows that CB-SPA can select variable subsets with more valuable variables and less multi-collinearity. Meanwhile, models established by the CB-SPA subset outperform basic SPA subsets in predicting nitrogen content in terms of both cross-validation and external prediction. Moreover, CB-SPA is assured to be more efficient, for the time cost in its selection procedure is one-twelfth that of the basic SPA.

Conditions of Mytilus edulis extracellular body fluids and shell composition in a pH-treatment experiment: Acid-base status, trace elements and δ11B

NASA Astrophysics Data System (ADS)

Heinemann, Agnes; Fietzke, Jan; Melzner, Frank; BöHm, Florian; Thomsen, JöRn; Garbe-SchöNberg, Dieter; Eisenhauer, Anton

2012-01-01

Mytilus edulis were cultured for 3 months under six different seawater pCO2 levels ranging from 380 to 4000 μatm. Specimen were taken from Kiel Fjord (Western Baltic Sea, Germany) which is a habitat with high and variable seawater pCO2 and related shifts in carbonate system speciation (e.g., low pH and low CaCO3 saturation state). Hemolymph (HL) and extrapallial fluid (EPF) samples were analyzed for pH and total dissolved inorganic carbon (CT) to calculate pCO2 and [HCO3-]. A second experiment was conducted for 2 months with three different pCO2 levels (380, 1400 and 4000 μatm). Boron isotopes (δ11B) were investigated by LA-MC-ICP-MS (Laser Ablation-Multicollector-Inductively Coupled Plasma-Mass Spectrometry) in shell portions precipitated during experimental treatment time. Additionally, elemental ratios (B/Ca, Mg/Ca and Sr/Ca) in the EPF of specimen from the second experiment were measured via ICP-OES (Inductively Coupled Plasma-Optical Emission Spectrometry). Extracellular pH was not significantly different in HL and EPF but systematically lower than ambient water pH. This is due to high extracellular pCO2 values, a prerequisite for metabolic CO2 excretion. No accumulation of extracellular [HCO3-] was measured. Elemental ratios (B/Ca, Mg/Ca and Sr/Ca) in the EPF increased slightly with pH which is in accordance with increasing growth and calcification rates at higher seawater pH values. Boron isotope ratios were highly variable between different individuals but also within single shells. This corresponds to a high individual variability in fluid B/Ca ratios and may be due to high boron concentrations in the organic parts of the shell. The mean δ11B value shows no trend with pH but appears to represent internal pH (EPF) rather than ambient water pH.

Increased variability of tornado occurrence in the United States.

PubMed

Brooks, Harold E; Carbin, Gregory W; Marsh, Patrick T

2014-10-17

Whether or not climate change has had an impact on the occurrence of tornadoes in the United States has become a question of high public and scientific interest, but changes in how tornadoes are reported have made it difficult to answer it convincingly. We show that, excluding the weakest tornadoes, the mean annual number of tornadoes has remained relatively constant, but their variability of occurrence has increased since the 1970s. This is due to a decrease in the number of days per year with tornadoes combined with an increase in days with many tornadoes, leading to greater variability on annual and monthly time scales and changes in the timing of the start of the tornado season. Copyright © 2014, American Association for the Advancement of Science.

Sustainability or Collapse: Interplay Between Decadal Climate Variability and Human Activities Matters

NASA Astrophysics Data System (ADS)

Lu, Y.; Hu, H.; Tian, F.

2016-12-01

The Aral Sea Crisis and the deterioration of Tarim River Basin are representative cases of emergent water deficit problems in arid areas. Comparing cases of water deficit problems in different regions and considering the in the perspective of socio-hydrology is helpful to obtain guidance on integrated management of arid area basins. Analyzing the interplay between decadal climate variability and human activities in both basins, the important role of human activities is observed. Decadal climate variability tempts people to adapt fast to increasing water resources and slowly to decreasing water resources, while using unsustainable technical measures to offset water shortage. Due to this asymmetry the situation deteriorates with technically enhanced capabilities of societies to exploit water resources, and more integrated long-term management capacity is in high demand.

Analysis of a two row hydrostatic journal bearing with variable properties, inertia effects and surface roughness

NASA Technical Reports Server (NTRS)

Braun, M. J.; Adams, M. L.; Mullen, R. L.

1985-01-01

A computer algorithm for simulation of hydrostatic journal bearing pressure-flow behavior has been generated. The effects taken into account are inertia, cavitation, variable properties (isothermal bearing) and roughness. The program has been specifically tailored for simulation of the hybrid bearing of the cryogenic turbopumps of the main shuttle engine. Due to the high pressure (515 psia) of the supply line no cavitation has been found. The influence of the roughness effects have been found to become important only when the surface-roughness order of magnitude is comparable with that of the bearing clearance itself. Pocket edge inertia and variable properties have been found to have quite an important influence upon the pocket pressure, field pressure distribution and lubricant mass flow.

High-frequency (8 to 16 kHz) reference thresholds and intrasubject threshold variability relative to ototoxicity criteria using a Sennheiser HDA 200 earphone.

PubMed

Frank, T

2001-04-01

The first purpose of this study was to determine high-frequency (8 to 16 kHz) thresholds for standardizing reference equivalent threshold sound pressure levels (RETSPLs) for a Sennheiser HDA 200 earphone. The second and perhaps more important purpose of this study was to determine whether repeated high-frequency thresholds using a Sennheiser HDA 200 earphone had a lower intrasubject threshold variability than the ASHA 1994 significant threshold shift criteria for ototoxicity. High-frequency thresholds (8 to 16 kHz) were obtained for 100 (50 male, 50 female) normally hearing (0.25 to 8 kHz) young adults (mean age of 21.2 yr) in four separate test sessions using a Sennheiser HDA 200 earphone. The mean and median high-frequency thresholds were similar for each test session and increased as frequency increased. At each frequency, the high-frequency thresholds were not significantly (p > 0.05) different for gender, test ear, or test session. The median thresholds at each frequency were similar to the 1998 interim ISO RETSPLs; however, large standard deviations and wide threshold distributions indicated very high intersubject threshold variability, especially at 14 and 16 kHz. Threshold repeatability was determined by finding the threshold differences between each possible test session comparison (N = 6). About 98% of all of the threshold differences were within a clinically acceptable range of +/-10 dB from 8 to 14 kHz. The threshold differences between each subject's second, third, and fourth minus their first test session were also found to determine whether intrasubject threshold variability was less than the ASHA 1994 criteria for determining a significant threshold shift due to ototoxicity. The results indicated a false-positive rate of 0% for a threshold shift > or = 20 dB at any frequency and a false-positive rate of 2% for a threshold shift >10 dB at two consecutive frequencies. This study verified that the output of high-frequency audiometers at 0 dB HL using Sennheiser HDA 200 earphones should equal the 1998 interim ISO RETSPLs from 8 to 16 kHz. Further, because the differences between repeated thresholds were well within +/-10 dB and had an extremely low false-positive rate in reference to the ASHA 1994 criteria for a significant threshold shift due to ototoxicity, a Sennheiser HDA 200 earphone can be used for serial monitoring to determine whether significant high-frequency threshold shifts have occurred for patients receiving potentially ototoxic drug therapy.

High intraspecific variability in the diet of a deep-sea nematode: Stable isotope and fatty acid analyses of Deontostoma tridentum on Chatham Rise, Southwest Pacific

NASA Astrophysics Data System (ADS)

Leduc, Daniel; Brown, Julie C. S.; Bury, Sarah J.; Lörz, Anne-Nina

2015-03-01

Small deep-sea organisms may exhibit a high degree of intraspecific variability in diet due to their ability to exploit a wide range of food sources and patchiness in food availability. Trophic interactions of small deep-sea benthic organisms, however, remain poorly understood. Here we describe spatial variation in diet/trophic level of the common deep-sea nematode Deontostoma tridentum on Chatham Rise, Southwest Pacific, using carbon and nitrogen stable isotope and fatty acid analyses. We also analysed sediment organic matter (SOM) and compared the isotopic composition of D. tridentum to other benthic and suprabenthic macrofaunal taxa with a variety of feeding modes. Variability in D. tridentum δ13C and δ15N signatures was high both among sites and within a single site on the southern flank of Chatham Rise. Among-site variation in SOM δ13C signatures was not sufficient to explain variation in nematode isotopic signatures. The presence of a positive correlation between δ13C and δ15N signatures of D. tridentum (both among and within sites) could suggest that differences in trophic level is the cause behind this variation. Nitrogen isotope data suggest the presence of 1-3 trophic levels in this species, which may reflect differences in prey availability, nematode body size, or habitat (benthic versus epizoic). Nematode δ15N values exceeded those of all other taxa we investigated, including other predators, but reasons for this enrichment remain unclear. The fatty acid composition of D. tridentum did not vary substantially between sites and was characterised by relatively high levels of 18:1n9 (15-20%) and polyunsaturated fatty acids (PUFAs; 22%). Although limited inferences can be made based on fatty acid composition due to the potential impacts of non-dietary factors, high levels of PUFAs indicate that D. tridentum represents a good source of these essential nutrients to higher trophic levels. In conclusion, our results show that (1) some deep-sea organisms exhibit a high degree of intraspecific variability in diet, and (2) nematodes may be an important source of PUFAs for larger animals in deep-sea environments, where the quality of SOM is low.

Radiative forcing over the conterminous United States due to contemporary land cover land use change and sensitivity to snow and interannual albedo variability

USGS Publications Warehouse

Barnes, Christopher A.; Roy, David P.

2010-01-01

Satellite-derived land cover land use (LCLU), snow and albedo data, and incoming surface solar radiation reanalysis data were used to study the impact of LCLU change from 1973 to 2000 on surface albedo and radiative forcing for 58 ecoregions covering 69% of the conterminous United States. A net positive surface radiative forcing (i.e., warming) of 0.029 Wm−2 due to LCLU albedo change from 1973 to 2000 was estimated. The forcings for individual ecoregions were similar in magnitude to current global forcing estimates, with the most negative forcing (as low as −0.367 Wm−2) due to the transition to forest and the most positive forcing (up to 0.337 Wm−2) due to the conversion to grass/shrub. Snow exacerbated both negative and positive forcing for LCLU transitions between snow-hiding and snow-revealing LCLU classes. The surface radiative forcing estimates were highly sensitive to snow-free interannual albedo variability that had a percent average monthly variation from 1.6% to 4.3% across the ecoregions. The results described in this paper enhance our understanding of contemporary LCLU change on surface radiative forcing and suggest that future forcing estimates should model snow and interannual albedo variation.

Future contingencies and photovoltaic system worth

NASA Astrophysics Data System (ADS)

Jones, G. J.; Thomas, M. G.; Bonk, G. J.

1982-09-01

The value of dispersed photovoltaic systems connected to the utility grid was calculated using the optimized generation planning program. The 1986 to 2001 time period was used for this study. Photovoltaic systems were dynamically integrated, up to 5% total capacity, into 9 NERC based regions under a range of future fuel and economic contingencies. Value was determined by the change in revenue requirements due to the photovoltaic additions. Displacement of high cost fuel was paramount to value, while capacity displacement was highly variable and dependent upon regional fuel mix.

Analysis of a Small Vigorous Mesoscale Convective System in a Low-Shear Environment. Pt. 1; Formation, Echo Structure and Lightning Behavior

NASA Technical Reports Server (NTRS)

Knupp, Kevin; Geerts, Bart; Goodman, Steven J.

1997-01-01

The precipitation output was highly variable due to the transient nature of the intense convective elements. This result is attributed to the high Richardson number (175) of the environment, which is much higher than that of the typical MCS environment. The development of the stratiform precipitation was accomplished locally (in situ), and not be advection of from the convective region. In situ charging of the stratiform region is also supported by the observations.

Photographic investigation into the mechanism of combustion in irregular detonation waves

NASA Astrophysics Data System (ADS)

Kiyanda, C. B.; Higgins, A. J.

2013-03-01

Irregular detonations are supersonic combustion waves in which the inherent multi-dimensional structure is highly variable. In such waves, it is questionable whether auto-ignition induced by shock compression is the only combustion mechanism present. Through the use of high-speed schlieren and self-emitted light photography, the velocity of the different components of detonation waves in a {{ CH}}_4+2{ O}_2 mixture is analyzed. The observed burn-out of unreacted pockets is hypothesized to be due to turbulent combustion.

Quantitative Analysis of High-Quality Officer Selection by Commandants Career-Level Education Board

DTIC Science & Technology

2017-03-01

due to Marines being evaluated before the end of their initial service commitment. Our research utilizes quantitative variables to analyze the...not provide detailed information why. B. LIMITATIONS The photograph analysis in this research is strictly limited to a quantitative analysis in...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS Approved for public release. Distribution is unlimited. QUANTITATIVE

Survival of Campylobacter jejuni and Campylobacter coli in retail broiler meat stored at -20, 4 and 12C, and development of predictive models of survival based on temperature and time

USDA-ARS?s Scientific Manuscript database

Retail broiler meat undergoes variable freezing and refrigeration temperatures during storage, transportation, display in retail outlets and in consumers’ refrigerators. Due to the relatively high prevalence of Campylobacter found in retail broilers and the low infective dose required to cause human...

Monitoring urban tree cover using object-based image analysis and public domain remotely sensed data

Treesearch

L. Monika Moskal; Diane M. Styers; Meghan Halabisky

2011-01-01

Urban forest ecosystems provide a range of social and ecological services, but due to the heterogeneity of these canopies their spatial extent is difficult to quantify and monitor. Traditional per-pixel classification methods have been used to map urban canopies, however, such techniques are not generally appropriate for assessing these highly variable landscapes....

Meta-analysis of RNA-Seq data across cohorts in a multi-season feed efficiency study of crossbred beef steers accounts for biological and technical variability within season

USDA-ARS?s Scientific Manuscript database

High-throughput sequencing is often used for studies of the transcriptome, particularly for comparisons between experimental conditions. Due to sequencing costs, a limited number of biological replicates are typically considered in such experiments, leading to low detection power for differential ex...

A multi-model approach to monitor emissions of CO2 and CO from an urban-industrial complex

NASA Astrophysics Data System (ADS)

Super, Ingrid; Denier van der Gon, Hugo A. C.; van der Molen, Michiel K.; Sterk, Hendrika A. M.; Hensen, Arjan; Peters, Wouter

2017-11-01

Monitoring urban-industrial emissions is often challenging because observations are scarce and regional atmospheric transport models are too coarse to represent the high spatiotemporal variability in the resulting concentrations. In this paper we apply a new combination of an Eulerian model (Weather Research and Forecast, WRF, with chemistry) and a Gaussian plume model (Operational Priority Substances - OPS). The modelled mixing ratios are compared to observed CO2 and CO mole fractions at four sites along a transect from an urban-industrial complex (Rotterdam, the Netherlands) towards rural conditions for October-December 2014. Urban plumes are well-mixed at our semi-urban location, making this location suited for an integrated emission estimate over the whole study area. The signals at our urban measurement site (with average enhancements of 11 ppm CO2 and 40 ppb CO over the baseline) are highly variable due to the presence of distinct source areas dominated by road traffic/residential heating emissions or industrial activities. This causes different emission signatures that are translated into a large variability in observed ΔCO : ΔCO2 ratios, which can be used to identify dominant source types. We find that WRF-Chem is able to represent synoptic variability in CO2 and CO (e.g. the median CO2 mixing ratio is 9.7 ppm, observed, against 8.8 ppm, modelled), but it fails to reproduce the hourly variability of daytime urban plumes at the urban site (R2 up to 0.05). For the urban site, adding a plume model to the model framework is beneficial to adequately represent plume transport especially from stack emissions. The explained variance in hourly, daytime CO2 enhancements from point source emissions increases from 30 % with WRF-Chem to 52 % with WRF-Chem in combination with the most detailed OPS simulation. The simulated variability in ΔCO :  ΔCO2 ratios decreases drastically from 1.5 to 0.6 ppb ppm-1, which agrees better with the observed standard deviation of 0.4 ppb ppm-1. This is partly due to improved wind fields (increase in R2 of 0.10) but also due to improved point source representation (increase in R2 of 0.05) and dilution (increase in R2 of 0.07). Based on our analysis we conclude that a plume model with detailed and accurate dispersion parameters adds substantially to top-down monitoring of greenhouse gas emissions in urban environments with large point source contributions within a ˜ 10 km radius from the observation sites.

Clinical Pharmacokinetics and Pharmacodynamics of Clopidogrel

PubMed Central

Jiang, Xi-Ling; Samant, Snehal; Lesko, Lawrence J.; Schmidt, Stephan

2017-01-01

Acute coronary syndromes (ACS) remain life-threatening disorders that are associated with high morbidity and mortality. Dual-antiplatelet therapy with aspirin and clopidogrel has shown to reduce cardiovascular events in patients with ACS. However, there is substantial inter-individual variability in response to clopidogrel treatment in addition to prolonged recovery of platelet reactivity as a result of irreversible binding to P2Y12 receptors. This high inter-individual variability in treatment response has primarily been associated with genetic polymorphisms in the genes encoding for cytochrome (CYP) 2C19 that affect clopidogrel’s pharmacokinetics. While FDA has issued a boxed warning for CYP2C19 poor metabolizers due to a potentially reduced efficacy in these patients, results from multivariate analyses suggest that additional factors, including age, sex, obesity, concurrent diseases and drug-drug interactions, may all contribute to the overall between-subject variability in treatment response. However, the extent to which each of these factors contributes to the overall variability and how they are interrelated is currently unclear. The objective of this review article is to provide a comprehensive update on the different factors that influence clopidogrel’s pharmacokinetics and pharmacodynamics and how they mechanistically contribute to inter-individual differences in response to clopidogrel treatment. PMID:25559342

The inorganic carbon distribution in Irish coastal waters

NASA Astrophysics Data System (ADS)

McGrath, Triona; Cave, Rachel; McGovern, Evin; Kivimae, Caroline

2014-05-01

Despite their relatively small surface area, coastal and shelf waters play a crucial role in the global climate through their influence on major biogeochemical cycles. Due to growing concern about ocean acidification as a result of increasing atmospheric CO2 concentrations, measurements of inorganic carbon parameters (dissolved inorganic carbon (DIC), total alkalinity (TA), pH and pCO2) have been made with increasing regularity over the past two decades. While it is clear that open ocean surface waters are acidifying at a fairly uniform rate ( -0.02 pH units per decade), less is known about changes in coastal waters due to the high complexity and spatial variability in these regions. Large spatial and temporal variability in coastal CO2 parameters is mainly due to nutrient inputs, biological activity, upwelling and riverine inputs of alkalinity and inorganic and organic carbon. The inorganic carbon system in Irish coastal waters is presented here, gathered from 9 surveys around the Irish coastline between 2009 and 2013. There are striking contrasts in the CO2 system between different areas, largely attributed to the bedrock composition of the nearby rivers. Freshwater end-member concentrations of TA, calculated from TA-salinity relationships in outer estuarine and nearshore coastal water, were supported by riverine TA data from the Irish Environmental Protection Agency. A large portion of Ireland is covered with limestone bedrock and as a result, many of the rivers have extremely high TA (>5000μmol/kg) due to the carbonate mineral content of the underlying bedrock. While such high TA has resulted in elevated pH and calcium carbonate saturation states in some coastal waters, (e.g. Galway Bay and Dublin Bay), the high TA in other areas was accompanied by particularly high DIC (e.g. River Shannon on the west coast), resulting in lower pH and aragonite/calcite saturation states and even CO2 degassing in the Shannon estuary. Due to non-limestone lithology in many parts of Northern Ireland, rivers and surrounding coastal water have lower TA and hence calcium carbonate saturation states that are directly related to salinity (e.g. Lough Foyle). This study highlights the complexity of the inorganic carbon system in Irish waters and the need for region-specific case studies to be carried out to assess the potential impacts of ocean acidification on coastal ecosystems.

Extreme Monsoon Rainfall Signatures Preserved in the Invasive Terrestrial Gastropod Lissachatina fulica

NASA Astrophysics Data System (ADS)

Ghosh, Prosenjit; Rangarajan, Ravi; Thirumalai, Kaustubh; Naggs, Fred

2017-11-01

Indian summer monsoon (ISM) rainfall lasts for a period of 4 months with large variations recorded in terms of rainfall intensity during its period between June and September. Proxy reconstructions of past ISM rainfall variability are required due to the paucity of long instrumental records. However, reconstructing subseasonal rainfall is extremely difficult using conventional hydroclimate proxies due to inadequate sample resolution. Here, we demonstrate the utility of the stable oxygen isotope composition of gastropod shells in reconstructing past rainfall on subseasonal timescales. We present a comparative isotopic study on present day rainwater and stable isotope ratios of precipitate found in the incremental growth bands of giant African land snail Lissachatina fulica (Bowdich) from modern day (2009) and in the historical past (1918). Isotopic signatures present in the growth bands allowed for the identification of ISM rainfall variability in terms of its active and dry spells in the modern as well as past gastropod record. Our results demonstrate the utility of gastropod growth band stable isotope ratios in semiquantitative reconstructions of seasonal rainfall patterns. High resolution climate records extracted from gastropod growth band stable isotopes (museum and archived specimens) can expand the scope for understanding past subseasonal-to-seasonal climate variability.

Hurricane Arthur and its effect on the short-term variability of pCO2 on the Scotian Shelf, NW Atlantic

NASA Astrophysics Data System (ADS)

Lemay, Jonathan; Thomas, Helmuth; Craig, Susanne E.; Burt, William J.; Fennel, Katja; Greenan, Blair J. W.

2018-04-01

The understanding of the seasonal variability of carbon cycling on the Scotian Shelf in the NW Atlantic Ocean has improved in recent years; however, very little information is available regarding its short-term variability. In order to shed light on this aspect of carbon cycling on the Scotian Shelf we investigate the effects of Hurricane Arthur, which passed the region on 5 July 2014. The hurricane caused a substantial decline in the surface water partial pressure of CO2 (pCO2), even though the Scotian Shelf possesses CO2-rich deep waters. High-temporal-resolution data of moored autonomous instruments demonstrate that there is a distinct layer of relatively cold water with low dissolved inorganic carbon (DIC) slightly above the thermocline, presumably due to a sustained population of phytoplankton. Strong storm-related wind mixing caused this cold intermediate layer with high phytoplankton biomass to be entrained into the surface mixed layer. At the surface, phytoplankton begin to grow more rapidly due to increased light. The combination of growth and the mixing of low DIC water led to a short-term reduction in the partial pressure of CO2 until wind speeds relaxed and allowed for the restratification of the upper water column. These hurricane-related processes caused a (net) CO2 uptake by the Scotian Shelf region that is comparable to the spring bloom, thus exerting a major impact on the annual CO2 flux budget.

Does high diurnal variability in a reef flat from Ofu, American Samoa confer resistance to ocean acidification?

NASA Astrophysics Data System (ADS)

Koweek, D.; Samuel, L.; Mucciarone, D. A.; Woodson, C. B.; Monismith, S. G.; Dunbar, R. B.

2012-12-01

Forecasts for coral reefs under various ocean acidification scenarios are becoming increasingly complex due to significant inter-site variability in biogeochemistry, ecology, and physical oceanography. The reef flats of Ofu, American Samoa are a potential end-member of this vulnerability spectrum due to extremely high diurnal variability in their biogeochemistry. Here we present coupled biogeochemical and physical oceanographic measurements from a shallow reef flat on Ofu in November 2011. We observed diurnal temperature ranges of up to 7°C, along with diurnal pH and dissolved oxygen ranges of 0.6 units, and 160 percent of saturation, respectively. Carbon system measurements were less extreme. Alkalinity varied between 2240-2360 μmol/kg and total dissolved inorganic carbon (TDIC) ranged between 1850-2100 μmol/kg during the diurnal cycle. These observations suggest diurnal ranges of ~240ppm CO2 and 1.5 units of ΩAr. The larger diurnal range in TDIC relative to alkalinity suggests a reef environment dominated by photosynthesis. From these observations, we explore the balance between the dominant biogeochemical processes of production and calcification on the reef flat in more detail, along with its implication for conferring resistance to ocean acidification. We use calcification rate estimates to provide insight to patterns of day and night growth and/or dissolution on the reef. Finally, we present evidence of tidal modulation of the biogeochemical signals and discuss the role of localized physical circulation in helping to determine a reef's vulnerability to ocean acidification.

Comparative Chromosome Map and Heterochromatin Features of the Gray Whale Karyotype (Cetacea).

PubMed

Kulemzina, Anastasia I; Proskuryakova, Anastasia A; Beklemisheva, Violetta R; Lemskaya, Natalia A; Perelman, Polina L; Graphodatsky, Alexander S

2016-01-01

Cetacean karyotypes possess exceptionally stable diploid numbers and highly conserved chromosomes. To date, only toothed whales (Odontoceti) have been analyzed by comparative chromosome painting. Here, we studied the karyotype of a representative of baleen whales, the gray whale (Eschrichtius robustus, Mysticeti), by Zoo-FISH with dromedary camel and human chromosome-specific probes. We confirmed a high degree of karyotype conservation and found an identical order of syntenic segments in both branches of cetaceans. Yet, whale chromosomes harbor variable heterochromatic regions constituting up to a third of the genome due to the presence of several types of repeats. To investigate the cause of this variability, several classes of repeated DNA sequences were mapped onto chromosomes of whale species from both Mysticeti and Odontoceti. We uncovered extensive intrapopulation variability in the size of heterochromatic blocks present in homologous chromosomes among 3 individuals of the gray whale by 2-step differential chromosome staining. We show that some of the heteromorphisms observed in the gray whale karyotype are due to distinct amplification of a complex of common cetacean repeat and heavy satellite repeat on homologous autosomes. Furthermore, we demonstrate localization of the telomeric repeat in the heterochromatin of both gray and pilot whale (Globicephala melas, Odontoceti). Heterochromatic blocks in the pilot whale represent a composite of telomeric and common repeats, while heavy satellite repeat is lacking in the toothed whale consistent with previous studies. © 2016 S. Karger AG, Basel.

Regional Community Climate Simulations with variable resolution meshes in the Community Earth System Model

NASA Astrophysics Data System (ADS)

Zarzycki, C. M.; Gettelman, A.; Callaghan, P.

2017-12-01

Accurately predicting weather extremes such as precipitation (floods and droughts) and temperature (heat waves) requires high resolution to resolve mesoscale dynamics and topography at horizontal scales of 10-30km. Simulating such resolutions globally for climate scales (years to decades) remains computationally impractical. Simulating only a small region of the planet is more tractable at these scales for climate applications. This work describes global simulations using variable-resolution static meshes with multiple dynamical cores that target the continental United States using developmental versions of the Community Earth System Model version 2 (CESM2). CESM2 is tested in idealized, aquaplanet and full physics configurations to evaluate variable mesh simulations against uniform high and uniform low resolution simulations at resolutions down to 15km. Different physical parameterization suites are also evaluated to gauge their sensitivity to resolution. Idealized variable-resolution mesh cases compare well to high resolution tests. More recent versions of the atmospheric physics, including cloud schemes for CESM2, are more stable with respect to changes in horizontal resolution. Most of the sensitivity is due to sensitivity to timestep and interactions between deep convection and large scale condensation, expected from the closure methods. The resulting full physics model produces a comparable climate to the global low resolution mesh and similar high frequency statistics in the high resolution region. Some biases are reduced (orographic precipitation in the western United States), but biases do not necessarily go away at high resolution (e.g. summertime JJA surface Temp). The simulations are able to reproduce uniform high resolution results, making them an effective tool for regional climate studies and are available in CESM2.

A study of variable thrust, variable specific impulse trajectories for solar system exploration

NASA Astrophysics Data System (ADS)

Sakai, Tadashi

A study has been performed to determine the advantages and disadvantages of variable thrust and variable Isp (specific impulse) trajectories for solar system exploration. There have been several numerical research efforts for variable thrust, variable Isp, power-limited trajectory optimization problems. All of these results conclude that variable thrust, variable Isp (variable specific impulse, or VSI) engines are superior to constant thrust, constant Isp (constant specific impulse; or CSI) engines. However, most of these research efforts assume a mission from Earth to Mars, and some of them further assume that these planets are circular and coplanar. Hence they still lack the generality. This research has been conducted to answer the following questions: (1) Is a VSI engine always better than a CSI engine or a high thrust engine for any mission to any planet with any time of flight considering lower propellant mass as the sole criterion? (2) If a planetary swing-by is used for a VSI trajectory, is the fuel savings of a VSI swing-by trajectory better than that of a CSI swing-by or high thrust swing-by trajectory? To support this research, an unique, new computer-based interplanetary trajectory calculation program has been created. This program utilizes a calculus of variations algorithm to perform overall optimization of thrust, Isp, and thrust vector direction along a trajectory that minimizes fuel consumption for interplanetary travel. It is assumed that the propulsion system is power-limited, and thus the compromise between thrust and Isp is a variable to be optimized along the flight path. This program is capable of optimizing not only variable thrust trajectories but also constant thrust trajectories in 3-D space using a planetary ephemeris database. It is also capable of conducting planetary swing-bys. Using this program, various Earth-originating trajectories have been investigated and the optimized results have been compared to traditional CSI and high thrust trajectory solutions. Results show that VSI rocket engines reduce fuel requirements for any mission compared to CSI rocket engines. Fuel can be saved by applying swing-by maneuvers for VSI engines; but the effects of swing-bys due to VSI engines are smaller than that of CSI or high thrust engines.

Nitrous oxide emissions from intensive agricultural systems: Variations between crops and seasons, key driving variables, and mean emission factors

NASA Astrophysics Data System (ADS)

Dobbie, K. E.; McTaggart, I. P.; Smith, K. A.

1999-11-01

Emissions of nitrous oxide from intensively managed agricultural fields were measured over 3 years. Exponential increases in flux occurred with increasing soil water- filled pore space (WFPS) and temperature; increases in soil mineral N content due to fertilizer application also stimulated emissions. Fluxes were low when any of these variables was below a critical value. The largest fluxes occurred when WFPS values were very high (70-90%), indicating that denitrification was the major process responsible. The relationships with the driving variables showed strong similarities to those reported for very different environments: irrigated sugar cane crops, pastures, and forest in the tropics. Annual emissions varied widely (0.3-18.4 kg N2O-N ha-1). These variations were principally due to the degree of coincidence of fertilizer application and major rainfall events. It is concluded therefore that several years' data are required from any agricultural ecosystem in a variable climate to obtain a robust estimate of mean N2O fluxes. The emissions from small-grain cereals (winter wheat and spring barley) were consistently lower (0.2-0.7 kg N2O-N per 100 kg N applied) than from cut grassland (0.3-5.8 kg N2O- N per 100 kg N). Crops such as broccoli and potatoes gave emissions of the same order as those from the grassland. Although these differences between crop types are not apparent in general data comparisons, there may well be distinct regional differences in the relative and absolute emissions from different crops, due to local factors relating to soil type, weather patterns, and agricultural management practices. This will only be determined by more detailed comparative studies.

Self-Heating Effects In Polysilicon Source Gated Transistors

PubMed Central

Sporea, R. A.; Burridge, T.; Silva, S. R. P.

2015-01-01

Source-gated transistors (SGTs) are thin-film devices which rely on a potential barrier at the source to achieve high gain, tolerance to fabrication variability, and low series voltage drop, relevant to a multitude of energy-efficient, large-area, cost effective applications. The current through the reverse-biased source barrier has a potentially high positive temperature coefficient, which may lead to undesirable thermal runaway effects and even device failure through self-heating. Using numerical simulations we show that, even in highly thermally-confined scenarios and at high current levels, self-heating is insufficient to compromise device integrity. Performance is minimally affected through a modest increase in output conductance, which may limit the maximum attainable gain. Measurements on polysilicon devices confirm the simulated results, with even smaller penalties in performance, largely due to improved heat dissipation through metal contacts. We conclude that SGTs can be reliably used for high gain, power efficient analog and digital circuits without significant performance impact due to self-heating. This further demonstrates the robustness of SGTs. PMID:26351099

Synoptic meteorological modes of variability for fine particulate matter (PM2.5) air quality in major metropolitan regions of China

NASA Astrophysics Data System (ADS)

Leung, Danny M.; Tai, Amos P. K.; Mickley, Loretta J.; Moch, Jonathan M.; van Donkelaar, Aaron; Shen, Lu; Martin, Randall V.

2018-05-01

In his study, we use a combination of multivariate statistical methods to understand the relationships of PM2.5 with local meteorology and synoptic weather patterns in different regions of China across various timescales. Using June 2014 to May 2017 daily total PM2.5 observations from ˜ 1500 monitors, all deseasonalized and detrended to focus on synoptic-scale variations, we find strong correlations of daily PM2.5 with all selected meteorological variables (e.g., positive correlation with temperature but negative correlation with sea-level pressure throughout China; positive and negative correlation with relative humidity in northern and southern China, respectively). The spatial patterns suggest that the apparent correlations with individual meteorological variables may arise from common association with synoptic systems. Based on a principal component analysis of 1998-2017 meteorological data to diagnose distinct meteorological modes that dominate synoptic weather in four major regions of China, we find strong correlations of PM2.5 with several synoptic modes that explain 10 to 40 % of daily PM2.5 variability. These modes include monsoonal flows and cold frontal passages in northern and central China associated with the Siberian High, onshore flows in eastern China, and frontal rainstorms in southern China. Using the Beijing-Tianjin-Hebei (BTH) region as a case study, we further find strong interannual correlations of regionally averaged satellite-derived annual mean PM2.5 with annual mean relative humidity (RH; positive) and springtime fluctuation frequency of the Siberian High (negative). We apply the resulting PM2.5-to-climate sensitivities to the Intergovernmental Panel on Climate Change (IPCC) Coupled Model Intercomparison Project Phase 5 (CMIP5) climate projections to predict future PM2.5 by the 2050s due to climate change, and find a modest decrease of ˜ 0.5 µg m-3 in annual mean PM2.5 in the BTH region due to more frequent cold frontal ventilation under the RCP8.5 future, representing a small climate benefit, but the RH-induced PM2.5 change is inconclusive due to the large inter-model differences in RH projections.

Extreme infrared variables from UKIDSS - II. An end-of-survey catalogue of eruptive YSOs and unusual stars

NASA Astrophysics Data System (ADS)

Lucas, P. W.; Smith, L. C.; Contreras Peña, C.; Froebrich, D.; Drew, J. E.; Kumar, M. S. N.; Borissova, J.; Minniti, D.; Kurtev, R.; Monguió, M.

2017-12-01

We present a catalogue of 618 high-amplitude infrared variable stars (1 < ΔK < 5 mag) detected by the two widely separated epochs of 2.2 μm data in the UKIDSS Galactic plane survey, from searches covering ∼1470 deg2. Most were discovered by a search of all fields at 30 < l < 230°. Sources include new dusty Mira variables, three new cataclysmic variable candidates, a blazar and a peculiar source that may be an interacting binary system. However, ∼60 per cent are young stellar obbjects (YSOs), based on spatial association with star-forming regions at distances ranging from 300 pc to over 10 kpc. This confirms our initial result in Contreras Peña et al. (Paper I) that YSOs dominate the high-amplitude infrared variable sky in the Galactic disc. It is also supported by recently published VISTA Variables in the Via Lactea (VVV) results at 295 < l < 350°. The spectral energy distributions of the YSOs indicate class I or flat-spectrum systems in most cases, as in the VVV sample. A large number of variable YSOs are associated with the Cygnus X complex and other groups are associated with the North America/Pelican nebula, the Gemini OB1 molecular cloud, the Rosette complex, the Cone nebula, the W51 star-forming region and the S86 and S236 H II regions. Most of the YSO variability is likely due to variable/episodic accretion on time-scales of years, albeit usually less extreme than classical FUors and EXors. Luminosities at the 2010 Wide-field Infrared Survey Explorer epoch range from ∼0.1 to 103 L⊙ but only rarely exceed 102.5 L⊙.

Quality requirements for veterinary hematology analyzers in small animals-a survey about veterinary experts' requirements and objective evaluation of analyzer performance based on a meta-analysis of method validation studies: bench top hematology analyzer.

PubMed

Cook, Andrea M; Moritz, Andreas; Freeman, Kathleen P; Bauer, Natali

2016-09-01

Scarce information exists about quality requirements and objective evaluation of performance of large veterinary bench top hematology analyzers. The study was aimed at comparing the observed total error (TEobs ) derived from meta-analysis of published method validation data to the total allowable error (TEa ) for veterinary hematology variables in small animals based on experts' opinions. Ideally, TEobs should be < TEa . An online survey was sent to veterinary experts in clinical pathology and small animal internal medicine for providing the maximal allowable deviation from a given result for each variable. Percent of TEa = (allowable median deviation/clinical threshold) * 100%. Second, TEobs for 3 laser-based bench top hematology analyzers (ADVIA 2120; Sysmex XT2000iV, and CellDyn 3500) was calculated based on method validation studies published between 2005 and 2013 (n = 4). The percent TEobs = 2 * CV (%) + bias (%). The CV was derived from published studies except for the ADVIA 2120 (internal data), and bias was estimated from the regression equation. A total of 41 veterinary experts (19 diplomates, 8 residents, 10 postgraduate students, 4 anonymous specialists) responded. The proposed range of TEa was wide, but generally ≤ 20%. The TEobs was < TEa for all variables and analyzers except for canine and feline HGB (high bias, low CV) and platelet counts (high bias, high CV). Overall, veterinary bench top analyzers fulfilled experts' requirements except for HGB due to method-related bias, and platelet counts due to known preanalytic/analytic issues. © 2016 American Society for Veterinary Clinical Pathology.

IODP Site 1476: 7.5 Million Year Record of Southeast African Climate

NASA Astrophysics Data System (ADS)

Cantu, K.; Norris, R. D.

2017-12-01

The primary focus of IODP Expedition 361 was Southeast African Climate. Site 1476 in the northern Mozambique Channel yielded a sediment record going back roughly 7.6 million years, a time frame particularly interesting due to its relevance to hominid evolution. Previous paleoclimate studies from the region have included lake sediments and soil carbonate isotopes, which have been interpreted as showing a long-term trend toward increasing aridity. Lake Malawi records from the last 1.3 million years show a change during the Mid-Pleistocene Transition (MPT) from high frequency variability and generally lower lake levels to higher amplitude variability and higher lake levels punctuated by long, severe droughts resulting in extreme and long-lasting low-stands. Site 1476 cores were scanned using X-Ray Fluorescence (XRF), which gives semi-quantitative elemental abundances. Elemental abundance ratios are used as proxies for a variety of climate-related signals, such as changes in weathering rates, the nature of terrigenous material, and grain size. Looking at the site's Fe/Ca, K/Ca, and Rb/Zr ratios, the period of 4.5 to about 1.5 million years ago shows higher terrigenous flux, higher clay flux, and a smaller grain size respectively than most of the previous 3 million years, followed by a steep decline before the MPT, before transitioning to a pattern of high amplitude oscillations post-MPT. These higher amplitude oscillations seem to correspond to Lake Malawi low stands in the post-MPT period, suggesting that the higher flux of terrigenous material to site 1476 is due to higher aridity resulting in lower vegetative cover. This data also point to high climate variability in the last million years, likely contributing to the evolution and ecological adaptability of our species.

Scale-free dynamics of the synchronization between sleep EEG power bands and the high frequency component of heart rate variability in normal men and patients with sleep apnea-hypopnea syndrome.

PubMed

Dumont, Martine; Jurysta, Fabrice; Lanquart, Jean-Pol; Noseda, André; van de Borne, Philippe; Linkowski, Paul

2007-12-01

To investigate the dynamics of the synchronization between heart rate variability and sleep electroencephalogram power spectra and the effect of sleep apnea-hypopnea syndrome. Heart rate and sleep electroencephalogram signals were recorded in controls and patients with sleep apnea-hypopnea syndrome that were matched for age, gender, sleep parameters, and blood pressure. Spectral analysis was applied to electrocardiogram and electroencephalogram sleep recordings to obtain power values every 20s. Synchronization likelihood was computed between time series of the normalized high frequency spectral component of RR-intervals and all electroencephalographic frequency bands. Detrended fluctuation analysis was applied to the synchronizations in order to qualify their dynamic behaviors. For all sleep bands, the fluctuations of the synchronization between sleep EEG and heart activity appear scale free and the scaling exponent is close to one as for 1/f noise. We could not detect any effect due to sleep apnea-hypopnea syndrome. The synchronizations between the high frequency component of heart rate variability and all sleep power bands exhibited robust fluctuations characterized by self-similar temporal behavior of 1/f noise type. No effects of sleep apnea-hypopnea syndrome were observed in these synchronizations. Sleep apnea-hypopnea syndrome does not affect the interdependence between the high frequency component of heart rate variability and all sleep power bands as measured by synchronization likelihood.

Observations and a model of gravity-wave variability in the middle atmosphere

NASA Technical Reports Server (NTRS)

Fritts, D. C.; Vincent, R. A.

1986-01-01

A major goal was to determine what portion of the gravity-wave frequency spectrum accounted for the majority of the momentum flux and divergence, as this has important implications for the middle atmosphere response. It was found that approx. 70% of the total flux and divergence was due to wave motions with observed periods less than 1 hour, consistent with expectations based on the shape of the observed gravity-wave spectrum (FrItts, 1984). This dominance of the momentum flux and divergence by high-frequency motions implies a potential for the modulation of those quantities by large-amplitude motions at lower frequencies. A second, striking aspect of the velocity and momentum flux data is its dramatic diurnal variability, particularly at certain levels. This variability is illustrated with the momentum flux, computed in 8-hr blocks. The dominant contributions here are due to waves with periods less than 1 hr. The variability with height and size of the mean square velocity in the west beam and the momentum flux, energed over the 3-day period. A detailed analysis of the various tidal motions present during this data interval was performed, and it was determined that variations in the zontal wind profile imposed by the diurnal tidal motion are probably responsible for the modulation of the gravity-wave amplitudes and momentum fluxes.

Variable expressivity of the phenotype in two families with brachydactyly type E, craniofacial dysmorphism, short stature and delayed bone age caused by novel heterozygous mutations in the PTHLH gene.

PubMed

Jamsheer, Aleksander; Sowińska-Seidler, Anna; Olech, Ewelina M; Socha, Magdalena; Kozłowski, Kazimierz; Pyrkosz, Antoni; Trzeciak, Tomasz; Materna-Kiryluk, Anna; Latos-Bieleńska, Anna

2016-05-01

Brachydactyly refers to shortening of digits due to hypoplasia or aplasia of bones forming the hands and/or feet. Isolated brachydactyly type E (BDE), which is characterized by shortened metacarpals and/or metatarsals, results in a small proportion of patients from HOXD13 or PTHLH mutations, although in the majority of cases molecular lesion remains unknown. BDE, like other brachydactylies, shows clinical heterogeneity with highly variable intrafamilial and interindividual expressivity. In this study, we investigated two Polish cases (one familial and one sporadic) presenting with BDE and additional symptoms due to novel PTHLH mutations. Apart from BDE, the affected family showed short stature, mild craniofacial dysmorphism and delayed bone age. Sanger sequencing of PTHLH revealed a novel heterozygous frameshift mutation c.258delC(p.N87Tfs*18) in two affected individuals and one relative manifesting mild brachydactyly. The sporadic patient, in addition to BDE, presented with craniofacial dysmorphism, normal stature and bone age, and was demonstrated to carry a de novo heterozygous c.166C>T(p.R56*) mutation. Our paper reports on the two novel truncating PTHLH variants, resulting in variable combination of BDE and other symptoms. Data shown here expand the knowledge on the phenotypic presentation of PTHLH mutations, highlighting significant clinical variability and incomplete penetrance of the PTHLH-related symptoms.

Atmospheric Teleconnection and Climate Variability: Affecting Rice Productivity of Bihar, India

NASA Astrophysics Data System (ADS)

Saini, A.

2017-12-01

Climate variability brought various negative results to the environment around us and area under rice crop in Bihar has also faced a lot of negative impacts due to variability in temperature and rainfall. Location of Bihar in Northern Plain of India automatically makes it prime location for agriculture and therefore variability in climatic variables brings highly sensitive results to the agricultural production (especially rice). In this study, rainfall and temperature variables are taken into consideration to investigate the impact on rice cultivated area. Change in climate variable with the passage of time is prevailing since the start of geological time scale, how the variability in climate variables has affected the major crops. Climate index of Pacific Ocean and Indian Ocean influences the seasonal weather in Bihar and therefore role of ENSO and IOD is an interesting point of inquiry. Does there exists direct relation between climate variability and area under agricultural crops? How many important variables directly signals towards the change in area under agriculture production? These entire questions are answered with respect to change in area under rice cultivation of Bihar State of India. Temperature, rainfall and ENSO are a good indicator with respect to rice cultivation in Indian subcontinent. Impact on the area under rice has been signaled through ONI, Niño3 and DMI. Increasing range of temperature in the rice productivity declining years is observed since 1990.

Does intrinsic light heterogeneity in Ricinus communis L. monospecific thickets drive species' population dynamics?

PubMed

Goyal, Neha; Shah, Kanhaiya; Sharma, Gyan Prakash

2018-06-19

Ricinus communis L. colonizes heterogeneous urban landscapes as monospecific thickets. The ecological understanding on colonization success of R. communis population due to variable light availability is lacking. Therefore, to understand the effect of intrinsic light heterogeneity on species' population dynamics, R. communis populations exposed to variable light availability (low, intermediate, and high) were examined for performance strategies through estimation of key vegetative, eco-physiological, biochemical, and reproductive traits. Considerable variability existed in studied plant traits in response to available light. Individuals inhabiting high-light conditions exhibited high eco-physiological efficiency and reproductive performance that potentially confers population boom. Individuals exposed to low light showed poor performance in terms of eco-physiology and reproduction, which attribute to bust. However, individuals in intermediate light were observed to be indeterminate to light availability, potentially undergoing trait modulations with uncertainty of available light. Heterogeneous light availability potentially drives the boom and bust cycles in R. communis monospecific thickets. Such boom and bust cycles subsequently affect species' dominance, persistence, collapse, and/or resurgence as an aggressive colonizer in contrasting urban environments. The study fosters extensive monitoring of R. communis thickets to probe underlying mechanism(s) affecting expansions and/or collapses of colonizing populations.

Impact of Climate Change and Human Intervention on River Flow Regimes

NASA Astrophysics Data System (ADS)

Singh, Rajendra; Mittal, Neha; Mishra, Ashok

2017-04-01

Climate change and human interventions like dam construction bring freshwater ecosystem under stress by changing flow regime. It is important to analyse their impact at a regional scale along with changes in the extremes of temperature and precipitation which further modify the flow regime components such as magnitude, timing, frequency, duration, and rate of change of flow. In this study, the Kangsabati river is chosen to analyse the hydrological alterations in its flow regime caused by dam, climate change and their combined impact using Soil and Water Assessment Tool (SWAT) and the Indicators of Hydrologic Alteration (IHA) program based on the Range of Variability Approach (RVA). Results show that flow variability is significantly reduced due to dam construction with high flows getting absorbed and pre-monsoon low flows being augmented by the reservoir. Climate change alone reduces the high peaks whereas a combination of dam and climate change significantly reduces variability by affecting both high and low flows, thereby further disrupting the functioning of riverine ecosystems. Analysis shows that in the Kangsabati basin, influence of dam is greater than that of the climate change, thereby emphasising the significance of direct human intervention. Keywords: Climate change, human impact, flow regime, Kangsabati river, SWAT, IHA, RVA.

Present and future ecological niche modeling of garter snake species from the Trans-Mexican Volcanic Belt

PubMed Central

García-Vázquez, Uri; D’Addario, Maristella

2018-01-01

Land use and climate change are affecting the abundance and distribution of species. The Trans-Mexican Volcanic Belt (TMVB) is a very diverse region due to geological history, geographic position, and climate. It is also one of the most disturbed regions in Mexico. Reptiles are particularly sensitive to environmental changes due to their low dispersal capacity and thermal ecology. In this study, we define the important environmental variables (considering climate, topography, and land use) and potential distribution (present and future) of the five Thamnophis species present in TMVB. To do so, we used the maximum entropy modeling software (MAXENT). First, we modeled to select the most important variables to explain the distribution of each species, then we modeled again using only the most important variables and projected these models to the future considering a middle-moderate climate change scenario (rcp45), and land use and vegetation variables for the year 2050 (generated according to land use changes that occurred between years 2002 and 2011). Arid vegetation had an important negative effect on habitat suitability for all species, and minimum temperature of the coldest month was important for four of the five species. Thamnophis cyrtopsis was the species with the lowest tolerance to minimum temperatures. The maximum temperature of the warmest month was important for T. scalaris and T. cyrtopsis. Low percentages of agriculture were positive for T. eques and T. melanogaster but, at higher values, agriculture had a negative effect on habitat suitability for both species. Elevation was the most important variable to explain T. eques and T. melanogaster potential distribution while distance to Abies forests was the most important variable for T. scalaris and T. scaliger. All species had a high proportion of their potential distribution in the TMVB. However, according to our models, all Thamnophis species will experience reductions in their potential distribution in this region. T. scalaris will suffer the biggest reduction because this species is limited by high temperatures and will not be able to shift its distribution upward, as it is already present in the highest elevations of the TMVB. PMID:29666767

Northern Hemisphere moisture variability during the Last Glacial period

NASA Astrophysics Data System (ADS)

Asmerom, Y.; Polyak, V. J.; Lachniet, M. S.

2013-12-01

It was previously shown that large oxygen isotope variability related to changing moisture sources in the southwestern United States (SW) match the Greenland ice core temperature record. The variations were attributed to changes in the ratio of winter to summer precipitation delivered to the SW, with lighter winter δ18O values compared to summer monsoon rainfall, due to meridonial shifts in the position of the polar jet stream, which directs winter storm tracks. Cold stadial δ18O excursions are associated with strongly negative values, while interstadials have higher than average δ18O values. Although these data documented moisture source variability to the SW, the question of effective moisture variability remains unanswered. Here we present new high-resolution δ18O and δ13C isotopic data from a precisely dated speleothem, FS-AH1, from Fort Stanton Cave, New Mexico USA. The sample grew continuously between 47.6 and 11.1 kyr. The new chronology is more precise than previous work due to high sample growth rate, new gains in efficiency provided by our upgraded Neptune MC-ICPMS and new more precise determinations of the half-lives of 230Th and 234U. The FS-AH1 δ18O and the Greenland δ18O data (on the GICC05 time scale) show a remarkable match, both with respect to stadials/interstadial amplitudes and variability, and in the overall long-term trend. Our interpretation of the δ18O data remains the same, an indicator of moisture source variability. The δ18O and δ13C isotopic data show no correlation (R2 <0.0001) because the δ18O primarily reflects differences in moisture sources and temperature (at least during large-scale excursions), while δ13C variability reflects the amount of effective moisture in the soil zone overlying the cave, with low δ13C attributed to high soil productivity, high effective moisture, and wet conditions. The stadial and interstadial events are expressed mutely, if at all, in the δ13C data, while the secular variation follows the change in Northern Hemisphere summer insolation (insolation), similar to other Northern Hemisphere data, such as the strength of the East Asian summer monsoon as recorded in the Hulu speleothem, although the match to the East Asian monsoon is inverse. The much diminished expression of stadials and interstadials and secular variations in the effective moisture proxy data that match insolation seem to be hemispherical in scale. In humid settings, such as east Asia monsoon regions, warm temperatures lead to northward shift of the ITCZ and increase in the strength of the Asian monsoon, while in the desert SW any increase in the strength in the North American monsoon is counterbalanced by decrease in winter moisture due to the northward shift of the polar jet stream and more importantly, the onset of more evaporative conditions. In contrast to the large and rapid shifts seen in the Greenland ice core data and the apparent shift in position in air masses, as indicated by our δ18O data, large-scale changes in moisture regimes in the Northern Hemisphere seem to be driven by changes in insolation. Locations that are sensitive to small changes in atmospheric pressure and/or sea surface temperature gradients may be the exception.

Data-Mining Toolset Developed for Determining Turbine Engine Part Life Consumption

NASA Technical Reports Server (NTRS)

Litt, Jonathan S.

2003-01-01

The current practice in aerospace turbine engine maintenance is to remove components defined as life-limited parts after a fixed time, on the basis of a predetermined number of flight cycles. Under this schedule-based maintenance practice, the worst-case usage scenario is used to determine the usable life of the component. As shown, this practice often requires removing a part before its useful life is fully consumed, thus leading to higher maintenance cost. To address this issue, the NASA Glenn Research Center, in a collaborative effort with Pratt & Whitney, has developed a generic modular toolset that uses data-mining technology to parameterize life usage models for maintenance purposes. The toolset enables a "condition-based" maintenance approach, where parts are removed on the basis of the cumulative history of the severity of operation they have experienced. The toolset uses data-mining technology to tune life-consumption models on the basis of operating and maintenance histories. The flight operating conditions, represented by measured variables within the engine, are correlated with repair records for the engines, generating a relationship between the operating condition of the part and its service life. As shown, with the condition-based maintenance approach, the lifelimited part is in service until its usable life is fully consumed. This approach will lower maintenance costs while maintaining the safety of the propulsion system. The toolset is a modular program that is easily customizable by users. First, appropriate parametric damage accumulation models, which will be functions of engine variables, must be defined. The tool then optimizes the models to match the historical data by computing an effective-cycle metric that reduces the unexplained variability in component life due to each damage mode by accounting for the variability in operational severity. The damage increment due to operating conditions experienced during each flight is used to compute the effective cycles and ultimately the replacement time. Utilities to handle data problems, such as gaps in the flight data records, are included in the toolset. The tool was demonstrated using the first stage, high-pressure turbine blade of the PW4077 engine (Pratt & Whitney, East Hartford, CT). The damage modes considered were thermomechanical fatigue and oxidation/erosion. Each PW4077 engine contains 82 first-stage, high-pressure turbine blades, and data from a fleet of engines were used to tune the life-consumption models. The models took into account not only measured variables within the engine, but also unmeasured variables such as engine health parameters that are affected by degradation of the engine due to aging. The tool proved effective at predicting the average number of blades scrapped over time due to each damage mode, per engine, given the operating history of the engine. The customizable tools are available to interested parties within the aerospace community.

Temporal and spatial variation in pharmaceutical concentrations in an urban river system.

PubMed

Burns, Emily E; Carter, Laura J; Kolpin, Dana W; Thomas-Oates, Jane; Boxall, Alistair B A

2018-06-15

Many studies have quantified pharmaceuticals in the environment, few however, have incorporated detailed temporal and spatial variability due to associated costs in terms of time and materials. Here, we target 33 physico-chemically diverse pharmaceuticals in a spatiotemporal exposure study into the occurrence of pharmaceuticals in the wastewater system and the Rivers Ouse and Foss (two diverse river systems) in the city of York, UK. Removal rates in two of the WWTPs sampled (a conventional activated sludge (CAS) and trickling filter plant) ranged from not eliminated (carbamazepine) to >99% (paracetamol). Data comparisons indicate that pharmaceutical exposures in river systems are highly variable regionally, in part due to variability in prescribing practices, hydrology, wastewater management, and urbanisation and that select annual median pharmaceutical concentrations observed in this study were higher than those previously observed in the European Union and Asia thus far. Significant spatial variability was found between all sites in both river systems, while seasonal variability was significant for 86% and 50% of compounds in the River Foss and Ouse, respectively. Seasonal variations in flow, in-stream attenuation, usage and septic effluent releases are suspected drivers behind some of the observed temporal exposure variability. When the data were used to evaluate a simple environmental exposure model for pharmaceuticals, mean ratios of predicted environmental concentrations (PECs), obtained using the model, to measured environmental concentrations (MECs) were 0.51 and 0.04 for the River Foss and River Ouse, respectively. Such PEC/MEC ratios indicate that the model underestimates actual concentrations in both river systems, but to a much greater extent in the larger River Ouse. Copyright © 2018 Elsevier Ltd. All rights reserved.

Does internal climate variability overwhelm climate change signals in streamflow? The upper Po and Rhone basin case studies.

PubMed

Fatichi, S; Rimkus, S; Burlando, P; Bordoy, R

2014-09-15

Projections of climate change effects in streamflow are increasingly required to plan water management strategies. These projections are however largely uncertain due to the spread among climate model realizations, internal climate variability, and difficulties in transferring climate model results at the spatial and temporal scales required by catchment hydrology. A combination of a stochastic downscaling methodology and distributed hydrological modeling was used in the ACQWA project to provide projections of future streamflow (up to year 2050) for the upper Po and Rhone basins, respectively located in northern Italy and south-western Switzerland. Results suggest that internal (stochastic) climate variability is a fundamental source of uncertainty, typically comparable or larger than the projected climate change signal. Therefore, climate change effects in streamflow mean, frequency, and seasonality can be masked by natural climatic fluctuations in large parts of the analyzed regions. An exception to the overwhelming role of stochastic variability is represented by high elevation catchments fed by glaciers where streamflow is expected to be considerably reduced due to glacier retreat, with consequences appreciable in the main downstream rivers in August and September. Simulations also identify regions (west upper Rhone and Toce, Ticino river basins) where a strong precipitation increase in the February to April period projects streamflow beyond the range of natural climate variability during the melting season. This study emphasizes the importance of including internal climate variability in climate change analyses, especially when compared to the limited uncertainty that would be accounted for by few deterministic projections. The presented results could be useful in guiding more specific impact studies, although design or management decisions should be better based on reliability and vulnerability criteria as suggested by recent literature. Copyright © 2013 Elsevier B.V. All rights reserved.

Radon and radioactivity at a town overlying Uranium ores in northern Greece.

PubMed

Kourtidis, K; Georgoulias, A K; Vlahopoulou, M; Tsirliganis, N; Kastelis, N; Ouzounis, K; Kazakis, N

2015-12-01

Extensive measurements of (222)Rn in the town of Xanthi in N Greece show that the part of the town overlying granite deposits and the outcrop of a uranium ore has exceptionally high indoor radon levels, with monthly means up to 1500 Bq m(-3). A large number of houses (40%) in this part of the town exhibit radon levels above 200 Bq m(-3) while 11% of the houses had radon levels above 400 Bq m(-3). Substantial interannual variability as well as the highest in Europe winter/summer ratios (up to 12) were observed in this part of the town, which consist of traditional stone masonry buildings of the late 19th-early 20th century. Measurements of (238)U and (232)Th content of building materials from these houses as well as radionuclide measurements in different floors show that the high levels of indoor radon measured in these buildings are not due to high radon emanation rates from the building materials themselves but rather due to high radon flux from the soil because of the underlying geology, high radon penetration rates into the buildings from underground due to the lack of solid concrete foundations in these buildings, or a combination thereof. From the meteorological variables studied, highest correlation with indoor (222)Rn was found with temperature (r(2) = 0.65). An indoor radon prognostic regression model using temperature, pressure and precipitation as input was developed, that reproduced indoor radon with r(2) = 0.69. Hence, meteorology is the main driving factor of indoor radon, with temperature being the most important determinant. Preliminary flux measurements indicate that the soil-atmosphere (222)Rn flux should be in the range 150-250 Bq m(-2) h(-1), which is in the upper 10% of flux values for Europe. Copyright © 2015 Elsevier Ltd. All rights reserved.

Chronic lymphocytic leukemia patients exposed to ionizing radiation due to the Chernobyl NPP accident--with focus on immunoglobulin heavy chain gene analysis.

PubMed

Abramenko, Iryna; Bilous, Nadia; Chumak, Anatoliy; Davidova, Ekaterina; Kryachok, Iryna; Martina, Zoya; Nechaev, Stanislav; Dyagil, Iryna; Bazyka, Dmytriy; Bebeshko, Vladimir

2008-04-01

Clinical data and immunoglobulin variable heavy chain (IgVH) gene configuration were analyzed in 47 CLL patients, exposed to ionizing radiation (IR) due to Chernobyl NPP accident, and 141 non-exposed patients. Clean-up workers of the second quarter of 1986 (n=19) were picked out as separate group with the highest number of unmutated cases (94.4%), increased usage of IgVH1-69 (33.3%) and IgVH3-21 (16.7%) genes, high frequency of secondary solid tumors (6 cases) and Richter transformation (4 cases). These preliminary data suggest that CLL in the most suffered contingent due to Chernobyl NPP accident might have some specific features.

Power Smoothing and MPPT for Grid-connected Wind Power Generation with Doubly Fed Induction Generator

NASA Astrophysics Data System (ADS)

Kai, Takaaki; Tanaka, Yuji; Kaneda, Hirotoshi; Kobayashi, Daichi; Tanaka, Akio

Recently, doubly fed induction generator (DFIG) and synchronous generator are mostly applied for wind power generation, and variable speed control and power factor control are executed for high efficiently for wind energy capture and high quality for power system voltage. In variable speed control, a wind speed or a generator speed is used for maximum power point tracking. However, performances of a wind generation power fluctuation due to wind speed variation have not yet investigated for those controls. The authors discuss power smoothing by those controls for the DFIG inter-connected to 6.6kV distribution line. The performances are verified using power system simulation software PSCAD/EMTDC for actual wind speed data and are examined from an approximate equation of wind generation power fluctuation for wind speed variation.

Cerebral autoregulation in the preterm newborn using near-infrared spectroscopy: a comparison of time-domain and frequency-domain analyses

NASA Astrophysics Data System (ADS)

Eriksen, Vibeke R.; Hahn, Gitte H.; Greisen, Gorm

2015-03-01

The aim was to compare two conventional methods used to describe cerebral autoregulation (CA): frequency-domain analysis and time-domain analysis. We measured cerebral oxygenation (as a surrogate for cerebral blood flow) and mean arterial blood pressure (MAP) in 60 preterm infants. In the frequency domain, outcome variables were coherence and gain, whereas the cerebral oximetry index (COx) and the regression coefficient were the outcome variables in the time domain. Correlation between coherence and COx was poor. The disagreement between the two methods was due to the MAP and cerebral oxygenation signals being in counterphase in three cases. High gain and high coherence may arise spuriously when cerebral oxygenation decreases as MAP increases; hence, time-domain analysis appears to be a more robust-and simpler-method to describe CA.

Identifying the interferences of irrigation on evapotranspiration variability over the Northern High Plains

NASA Astrophysics Data System (ADS)

Zeng, R.; Cai, X.

2016-12-01

Irrigation has considerably interfered with hydrological processes in arid and semi-arid areas with heavy irrigated agriculture. With the increasing demand for food production and evaporative demand due to climate change, irrigation water consumption is expected to increase, which would aggravate the interferences to hydrologic processes. Current studies focus on the impact of irrigation on the mean value of evapotranspiration (ET) at either local or regional scale, however, how irrigation changes the variability of ET has not been well understood. This study analyzes the impact of extensive irrigation on ET variability in the Northern High Plains. We apply an ET variance decomposition framework developed from our previous work to quantify the effects of both climate and irrigation on ET variance in the Northern High Plains watersheds. Based on climate and water table observations, we assess the monthly ET variance and its components for two periods: 1930s-1960s with less irrigation development 970s-2010s with more development. It is found that irrigation not only caused the well-recognized groundwater drawdown and stream depletion problems in the region, but also buffered ET variance from climatic fluctuations. In addition to increasing food productivity, irrigation also stabilizes crop yield by mitigating the impact of hydroclimatic variability. With complementary water supply from irrigation, ET often approaches to the potential ET, and thus the observed ET variance is more attributed to climatic variables especially temperature; meanwhile irrigation causes significant seasonal fluctuations to groundwater storage. For sustainable water resources management in the Northern High Plains, we argue that both the mean value and the variance of ET should be considered together for the regulation of irrigation in this region.

High intralocus variability and interlocus recombination promote immunological diversity in a minimal major histocompatibility system.

PubMed

Wilson, Anthony B; Whittington, Camilla M; Bahr, Angela

2014-12-20

The genes of the major histocompatibility complex (MHC/MH) have attracted considerable scientific interest due to their exceptional levels of variability and important function as part of the adaptive immune system. Despite a large number of studies on MH class II diversity of both model and non-model organisms, most research has focused on patterns of genetic variability at individual loci, failing to capture the functional diversity of the biologically active dimeric molecule. Here, we take a systematic approach to the study of MH variation, analyzing patterns of genetic variation at MH class IIα and IIβ loci of the seahorse, which together form the immunologically active peptide binding cleft of the MH class II molecule. The seahorse carries a minimal class II system, consisting of single copies of both MH class IIα and IIβ, which are physically linked and inherited in a Mendelian fashion. Both genes are ubiquitously expressed and detectible in the brood pouch of male seahorses throughout pregnancy. Genetic variability of the two genes is high, dominated by non-synonymous variation concentrated in their peptide-binding regions. Coding variation outside these regions is negligible, a pattern thought to be driven by intra- and interlocus recombination. Despite the tight physical linkage of MH IIα and IIβ loci, recombination has produced novel composite alleles, increasing functional diversity at sites responsible for antigen recognition. Antigen recognition by the adaptive immune system of the seahorse is enhanced by high variability at both MH class IIα and IIβ loci. Strong positive selection on sites involved in pathogen recognition, coupled with high levels of intra- and interlocus recombination, produce a patchwork pattern of genetic variation driven by genetic hitchhiking. Studies focusing on variation at individual MH loci may unintentionally overlook an important component of ecologically relevant variation.

Test and cull of high risk Coxiella burnetii infected pregnant dairy goats is not feasible due to poor test performance.

PubMed

Hogerwerf, Lenny; Koop, Gerrit; Klinkenberg, Don; Roest, Hendrik I J; Vellema, Piet; Nielen, Mirjam

2014-05-01

A major human Q fever epidemic occurred in The Netherlands during 2007-2009. In response, all pregnant goats from infected herds were culled before the 2010 kidding season without individual testing. The aim of this study was to assess whether high risk animals from recently infected naive herds can be identified by diagnostic testing. Samples of uterine fluid, milk and vaginal mucus from 203 euthanized pregnant goats were tested by PCR or ELISA. The results suggest that testing followed by culling of only the high risk animals is not a feasible method for protecting public health, mainly due to the low specificity of the tests and variability between herds. The risk of massive bacterial shedding during abortion or parturition can only be prevented by removal of all pregnant animals from naive recently infected herds. Copyright © 2014 Elsevier Ltd. All rights reserved.

[Predictors of the duration of non-work-related sick leave due to anxiety disorders].

PubMed

Catalina-Romero, Carlos; Martínez-Muñoz, Paloma; Quevedo-Aguado, Luis; Ruiz-Moraga, Montserrat; Fernández-Labandera, Carlos; Calvo-Bonacho, Eva

2013-01-01

To analyze the duration of non-work-related sick leave due to anxiety disorders and to identify demographic, occupational and clinical variables that may contribute to its prediction. We performed a prospective cohort study of 1,161 workers with an episode of non-work-related sick leave due to an anxiety disorder, belonging to the insured population of a mutual insurance company. We assessed the duration of non-work-related sick leave episodes and the main potentially related demographic, occupational and clinical variables. All non-work-related sick leave processes were followed-up until discharge. Cox regression analyses were conducted to establish the predictors of non-work-related sick leave duration. The median duration of non-work-related sick leave due to anxiety disorders was 83 days. In a multivariate analysis, the following factors were identified as being significantly associated with increases in the duration of sick leave (p <0.05): age of over 35 years, lower educational level (primary school studies, secondary school studies or high-school diploma vs. university degree), and the existence of comorbidity and unemployment occurring during the sick leave. In contrast, being separated or divorced was associated with an earlier return to work (p <0.05). Anxiety disorders are associated with long periods of non-work-related sick leave compared with other disorders and standard time duration. Demographic, occupational and clinical variables collected at the initial assessment of the sick leave episode would help to identify groups with an increased risk of prolonged sick leave, requiring strategies to facilitate return to work. Copyright © 2011 SESPAS. Published by Elsevier Espana. All rights reserved.

Impacts of climate variability and change on crop yield in sub-Sahara Africa

NASA Astrophysics Data System (ADS)

Pan, S.; Zhang, J.; Yang, J.; Chen, G.; Xu, R.; Zhang, B.; Lou, Y.

2017-12-01

Much concern has been raised about the impacts of climate change and climate extremes on Africa's food security. The impact of climate change on Africa's agriculture is likely to be severe compared to other continents due to high rain-fed agricultural dependence, and limited ability to mitigate and adapt to climate change. In recent decades, warming in Africa is more pronounced and faster than the global average and this trend is likely to continue in the future. However, quantitative assessment on impacts of climate extremes and climate change on crop yield has not been well investigated yet. By using an improved agricultural module of the Dynamic Land Ecosystem Model (DLEM-AG2) driven by spatially-explicit information on land use, climate and other environmental changes, we have assessed impacts of historical climate variability and future climate change on food crop yield across the sub-Sahara Africa during1980-2016 and the rest of the 21st century (2017-2099). Our simulated results indicate that African crop yield in the past three decades shows an increasing trend primarily due to cropland expansion. However, crop yield shows substantially spatial and temporal variation due to inter-annual and inter-decadal climate variability and spatial heterogeneity of environmental drivers. Droughts have largely reduced crop yield in the most vulnerable regions of Sub-Sahara Africa. Future projections with DLEM-AG2 show that food crop production in Sub-Sahara Africa would be favored with limiting end-of-century warming to below 1.50 C.

Wind-tunnel investigation to determine the low speed yawing stability derivatives of a twin jet fighter model at high angles of attack

NASA Technical Reports Server (NTRS)

Coe, P. L., Jr.; Newsom, W. A., Jr.

1974-01-01

An investigation was conducted to determine the low-speed yawing stability derivatives of a twin-jet fighter airplane model at high angles of attack. Tests were performed in a low-speed tunnel utilizing variable-curvature walls to simulate pure yawing motion. The results of the study showed that at angles of attack below the stall the yawing derivatives were essentially independent of the yawing velocity and sideslip angle. However, at angles of attack above the stall some nonlinear variations were present and the derivatives were strongly dependent upon sideslip angle. The results also showed that the rolling moment due to yawing was primarily due to the wing-fuselage combination, and that at angles of attack below the stall both the vertical and horizontal tails produced significant contributions to the damping in yaw. Additionally, the tests showed that the use of the forced-oscillation data to represent the yawing stability derivatives is questionable, at high angles of attack, due to large effects arising from the acceleration in sideslip derivatives.

Direct estimation and correction of bias from temporally variable non-stationary noise in a channelized Hotelling model observer.

PubMed

Fetterly, Kenneth A; Favazza, Christopher P

2016-08-07

Channelized Hotelling model observer (CHO) methods were developed to assess performance of an x-ray angiography system. The analytical methods included correction for known bias error due to finite sampling. Detectability indices ([Formula: see text]) corresponding to disk-shaped objects with diameters in the range 0.5-4 mm were calculated. Application of the CHO for variable detector target dose (DTD) in the range 6-240 nGy frame(-1) resulted in [Formula: see text] estimates which were as much as 2.9×  greater than expected of a quantum limited system. Over-estimation of [Formula: see text] was presumed to be a result of bias error due to temporally variable non-stationary noise. Statistical theory which allows for independent contributions of 'signal' from a test object (o) and temporally variable non-stationary noise (ns) was developed. The theory demonstrates that the biased [Formula: see text] is the sum of the detectability indices associated with the test object [Formula: see text] and non-stationary noise ([Formula: see text]). Given the nature of the imaging system and the experimental methods, [Formula: see text] cannot be directly determined independent of [Formula: see text]. However, methods to estimate [Formula: see text] independent of [Formula: see text] were developed. In accordance with the theory, [Formula: see text] was subtracted from experimental estimates of [Formula: see text], providing an unbiased estimate of [Formula: see text]. Estimates of [Formula: see text] exhibited trends consistent with expectations of an angiography system that is quantum limited for high DTD and compromised by detector electronic readout noise for low DTD conditions. Results suggest that these methods provide [Formula: see text] estimates which are accurate and precise for [Formula: see text]. Further, results demonstrated that the source of bias was detector electronic readout noise. In summary, this work presents theory and methods to test for the presence of bias in Hotelling model observers due to temporally variable non-stationary noise and correct this bias when the temporally variable non-stationary noise is independent and additive with respect to the test object signal.

The relationship between cadmium and phosphate in the Atlantic Ocean unravelled

NASA Astrophysics Data System (ADS)

Middag, Rob; van Heuven, Steven M. A. C.; Bruland, Kenneth W.; de Baar, Hein J. W.

2018-06-01

Cadmium (Cd) is not generally considered a nutrient element, but behaves like a nutrient in the oceans and might play an important role in ocean biology after all. The relationship between Cd and the nutrient phosphate (PO4) has been studied for over 40 yrs, but the debate on the driving mechanism and reason behind the 'kink', a change in the steepness of the slope is ongoing. Using new data of high accuracy and spatial resolution covering the West-Atlantic Ocean from north to south, in combination with a robust extended optimum multiparameter (eOMP) water mass model, we show that mixing between different water masses is the dominant factor explaining the observed correlation and its kink. Regeneration of Cd via remineralisation explains the smaller scale variability, notably in the surface ocean. Observations imply the availability of Cd in surface waters determines the Cd-uptake and thus the Cd:PO4 remineralisation ratio. This ratio is variable between different ocean regions, notably between the northern and southern high latitude oceans. Due to their role in deep water formation, both the northern and southern high latitude oceans are a driving factor in the Atlantic and global Cd and PO4 relation. Outside the Atlantic Ocean, the classical kink is not expected, but the relationship is by no means linear. Most likely, this is due to the interaction between low latitude surface waters and subsurface waters from high latitude origin, but more data are required to assess this in detail.

Job stress as a risk factor for absences among manual workers: a 12-month follow-up study

PubMed Central

HEO, Yong-Seok; LEEM, Jong-Han; PARK, Shin-Goo; JUNG, Dal-Young; KIM, Hwan-Cheol

2015-01-01

This study was conducted to evaluate the impact of job stress on absence from work caused by illnesses and accidents through a prospective research design. A total of 2,349 manual workers were included in this analysis. In the first survey, job stress was determined using the Korean Occupational Stress Scale-Short Form. In the second survey, information on absence due to accidents or illnesses during the past one year was obtained through a questionnaire. The relationship was analyzed using a logistic regression model with multiple imputation. After adjusting for confounding variables for males, absence due to accidents was statistically associated with high job demand, insufficient job control, inadequate social support, and organizational injustice. In addition, high job demands and organizational injustice were related to increased absence due to illnesses in both genders. A lack of reward was associated with increased absence due to illnesses among female workers. We found that job stress was associated with a higher risk of absence caused by accidents or illnesses of manual workers. PMID:26212413

Job stress as a risk factor for absences among manual workers: a 12-month follow-up study.

PubMed

Heo, Yong-Seok; Leem, Jong-Han; Park, Shin-Goo; Jung, Dal-Young; Kim, Hwan-Cheol

2015-01-01

This study was conducted to evaluate the impact of job stress on absence from work caused by illnesses and accidents through a prospective research design. A total of 2,349 manual workers were included in this analysis. In the first survey, job stress was determined using the Korean Occupational Stress Scale-Short Form. In the second survey, information on absence due to accidents or illnesses during the past one year was obtained through a questionnaire. The relationship was analyzed using a logistic regression model with multiple imputation. After adjusting for confounding variables for males, absence due to accidents was statistically associated with high job demand, insufficient job control, inadequate social support, and organizational injustice. In addition, high job demands and organizational injustice were related to increased absence due to illnesses in both genders. A lack of reward was associated with increased absence due to illnesses among female workers. We found that job stress was associated with a higher risk of absence caused by accidents or illnesses of manual workers.

Combined effects of short-term rainfall patterns and soil texture on nitrogen cycling -- A Modeling Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gu, C.; Riley, W.J.

2009-11-01

Precipitation variability and magnitude are expected to change in many parts of the world over the 21st century. We examined the potential effects of intra-annual rainfall patterns on soil nitrogen (N) transport and transformation in the unsaturated soil zone using a deterministic dynamic modeling approach. The model (TOUGHREACT-N), which has been tested and applied in several experimental and observational systems, mechanistically accounts for microbial activity, soil-moisture dynamics that respond to precipitation variability, and gaseous and aqueous tracer transport in the soil. Here, we further tested and calibrated the model against data from a precipitation variability experiment in a tropical systemmore » in Costa Rica. The model was then used to simulate responses of soil moisture, microbial dynamics, nitrogen (N) aqueous and gaseous species, N leaching, and N trace-gas emissions to changes in rainfall patterns; the effect of soil texture was also examined. The temporal variability of nitrate leaching and NO, N{sub 2}, and N{sub 2}O effluxes were significantly influenced by rainfall dynamics. Soil texture combined with rainfall dynamics altered soil moisture dynamics, and consequently regulated soil N responses to precipitation changes. The clay loam soil more effectively buffered water stress during relatively long intervals between precipitation events, particularly after a large rainfall event. Subsequent soil N aqueous and gaseous losses showed either increases or decreases in response to increasing precipitation variability due to complex soil moisture dynamics. For a high rainfall scenario, high precipitation variability resulted in as high as 2.4-, 2.4-, 1.2-, and 13-fold increases in NH{sub 3}, NO, N{sub 2}O and NO{sub 3}{sup -} fluxes, respectively, in clay loam soil. In sandy loam soil, however, NO and N{sub 2}O fluxes decreased by 15% and 28%, respectively, in response to high precipitation variability. Our results demonstrate that soil N cycling responses to increasing precipitation variability depends on precipitation amount and soil texture, and that accurate prediction of future N cycling and gas effluxes requires models with relatively sophisticated representation of the relevant processes.« less

Variable input observer for state estimation of high-rate dynamics

NASA Astrophysics Data System (ADS)

Hong, Jonathan; Cao, Liang; Laflamme, Simon; Dodson, Jacob

2017-04-01

High-rate systems operating in the 10 μs to 10 ms timescale are likely to experience damaging effects due to rapid environmental changes (e.g., turbulence, ballistic impact). Some of these systems could benefit from real-time state estimation to enable their full potential. Examples of such systems include blast mitigation strategies, automotive airbag technologies, and hypersonic vehicles. Particular challenges in high-rate state estimation include: 1) complex time varying nonlinearities of system (e.g. noise, uncertainty, and disturbance); 2) rapid environmental changes; 3) requirement of high convergence rate. Here, we propose using a Variable Input Observer (VIO) concept to vary the input space as the event unfolds. When systems experience high-rate dynamics, rapid changes in the system occur. To investigate the VIO's potential, a VIO-based neuro-observer is constructed and studied using experimental data collected from a laboratory impact test. Results demonstrate that the input space is unique to different impact conditions, and that adjusting the input space throughout the dynamic event produces better estimations than using a traditional fixed input space strategy.

Identifying Changes in the Probability of High Temperature, High Humidity Heat Wave Events

NASA Astrophysics Data System (ADS)

Ballard, T.; Diffenbaugh, N. S.

2016-12-01

Understanding how heat waves will respond to climate change is critical for adequate planning and adaptation. While temperature is the primary determinant of heat wave severity, humidity has been shown to play a key role in heat wave intensity with direct links to human health and safety. Here we investigate the individual contributions of temperature and specific humidity to extreme heat wave conditions in recent decades. Using global NCEP-DOE Reanalysis II daily data, we identify regional variability in the joint probability distribution of humidity and temperature. We also identify a statistically significant positive trend in humidity over the eastern U.S. during heat wave events, leading to an increased probability of high humidity, high temperature events. The extent to which we can expect this trend to continue under climate change is complicated due to variability between CMIP5 models, in particular among projections of humidity. However, our results support the notion that heat wave dynamics are characterized by more than high temperatures alone, and understanding and quantifying the various components of the heat wave system is crucial for forecasting future impacts.

Estimation of potential runoff-contributing areas in Kansas using topographic and soil information

USGS Publications Warehouse

Juracek, Kyle E.

1999-01-01

Digital topographic and soil information was used to estimate potential runoff-contributing areas throughout Kansas. The results then were used to compare 91 selected subbasins representing soil, slope, and runoff variability. Potential runoff-contributing areas were estimated collectively for the processes of infiltration-excess and saturation-excess overland flow using a set of environmental conditions that represented very high, high, moderate, low, very low, and extremely low potential runoff. For infiltration-excess overland flow, various rainfall-intensity and soil-permeability values were used. For saturation-excess overland flow, antecedent soil-moisture conditions and a topographic wetness index were used. Results indicated that very low potential-runoff conditions provided the best ability to distinguish the 91 selected subbasins as having relatively high or low potential runoff. The majority of the subbasins with relatively high potential runoff are located in the eastern half of the State where soil permeability generally is less and precipitation typically is greater. The ability to distinguish the subbasins as having relatively high or low potential runoff was possible mostly due to the variability of soil permeability across the State.

Vapor concentration monitor

DOEpatents

Bayly, John G.; Booth, Ronald J.

1977-01-01

An apparatus for monitoring the concentration of a vapor, such as heavy water, having at least one narrow bandwidth in its absorption spectrum, in a sample gas such as air. The air is drawn into a chamber in which the vapor content is measured by means of its radiation absorption spectrum. High sensitivity is obtained by modulating the wavelength at a relatively high frequency without changing its optical path, while high stability against zero drift is obtained by the low frequency interchange of the sample gas to be monitored and of a reference sample. The variable HDO background due to natural humidity is automatically corrected.

Using high-frequency nitrogen and carbon measurements to decouple temporal dynamics of catchment and in-stream transport and reaction processes in a headwater stream

NASA Astrophysics Data System (ADS)

Blaen, P.; Riml, J.; Khamis, K.; Krause, S.

2017-12-01

Within river catchments across the world, headwater streams represent important sites of nutrient transformation and uptake due to their high rates of microbial community processing and relative abundance in the landscape. However, separating the combined influence of in-stream transport and reaction processes from the overall catchment response can be difficult due to spatio-temporal variability in nutrient and organic matter inputs, flow regimes, and reaction rates. Recent developments in optical sensor technologies enable high-frequency, in situ nutrient measurements, and thus provide opportunities for greater insights into in-stream processes. Here, we use in-stream observations of hourly nitrate (NO3-N), dissolved organic carbon (DOC) and dissolved oxygen (DO) measurements from paired in situ sensors that bound a 1 km headwater stream reach in a mixed-use catchment in central England. We employ a spectral approach to decompose (1) variances in solute loading from the surrounding landscape, and (2) variances in reach-scale in-stream nutrient transport and reaction processes. In addition, we estimate continuous rates of reach-scale NO3-N and DOC assimilation/dissimilation, ecosystem respiration and primary production. Comparison of these results over a range of hydrological conditions (baseflow, variable storm events) and timescales (event-based, diel, seasonal) facilitates new insights into the physical and biogeochemical processes that drive in-stream nutrient dynamics in headwater streams.

18-year variability of ultraviolet radiation penetration in the mid-latitude coastal waters of the western boundary Pacific

NASA Astrophysics Data System (ADS)

Kuwahara, Victor S.; Nozaki, Sena; Nakano, Junji; Toda, Tatsuki; Kikuchi, Tomohiko; Taguchi, Satoru

2015-07-01

The 18-year time-series shows in situ ultraviolet radiation (UVR) and photosynthetically active radiation (PAR) diffuse attenuation coefficient Kd(λ) have recurrent seasonal variability of high/low attenuation during summer/winter months, respectively, dependent on variability in water column stratification and concentrations of bio-optical properties. The mid-latitude coastal survey station displayed significant seasonality of the mixed layer depth (MLD) between 12 and 82 m which modified the distribution of chlorophyll a (4.6-24.9 mg m-2) and absorption of colored dissolved organic matter [aCDOM(320 nm) 0.043-1.34 m-1]. The median Kd(320 nm) displayed significant seasonality at 0.19-0.74 m-1 (C.V. = 44.1%) and seasonal variability within the euphotic layer [Z10%(320 nm) = 7-20%]. High attenuation of UVR with relatively moderate attenuation of PAR was consistently observed during the summer months when increased concentrations of terrestrially derived CDOM coupled with a shallow MLD were present. The winter season showed the opposite of low UVR and PAR attenuation due to a relatively deeper MLD coupled with low concentrations of bio-optical properties. Although the long term Kd(λ) did not vary significantly during the time-series, analysis of the interannual variability suggests there are positive and negative phases following the Pacific Decadal Oscillation (PDO) vis-a-vis variability in bio-optical properties (p < 0.001).

Physiological and behavioral indices of emotion dysregulation as predictors of outcome from cognitive behavioral therapy and acceptance and commitment therapy for anxiety.

PubMed

Davies, Carolyn D; Niles, Andrea N; Pittig, Andre; Arch, Joanna J; Craske, Michelle G

2015-03-01

Identifying for whom and under what conditions a treatment is most effective is an essential step toward personalized medicine. The current study examined pre-treatment physiological and behavioral variables as predictors and moderators of outcome in a randomized clinical trial comparing cognitive behavioral therapy (CBT) and acceptance and commitment therapy (ACT) for anxiety disorders. Sixty individuals with a DSM-IV defined principal anxiety disorder completed 12 sessions of either CBT or ACT. Baseline physiological and behavioral variables were measured prior to entering treatment. Self-reported anxiety symptoms were assessed at pre-treatment, post-treatment, and 6- and 12-month follow-up from baseline. Higher pre-treatment heart rate variability was associated with worse outcome across ACT and CBT. ACT outperformed CBT for individuals with high behavioral avoidance. Subjective anxiety levels during laboratory tasks did not predict or moderate treatment outcome. Due to small sample sizes of each disorder, disorder-specific predictors were not tested. Future research should examine these predictors in larger samples and across other outcome variables. Lower heart rate variability was identified as a prognostic indicator of overall outcome, whereas high behavioral avoidance was identified as a prescriptive indicator of superior outcome from ACT versus CBT. Investigation of pre-treatment physiological and behavioral variables as predictors and moderators of outcome may help guide future treatment-matching efforts. Copyright © 2014 Elsevier Ltd. All rights reserved.

The influence of prescribed fire and burn interval on fuel loads in four North Carolina forest ecosystems

Treesearch

M.J. Gavazzi; S.G. McNulty

2014-01-01

Prescribed fire is an important management tool in southern US forests, with more acres burned in the South than any other region of the US. Research from prescribed fire studies shows high temporal and spatial variability in available fuel loads due to physiographic, edaphic, meteorological and biological factors. In an effort to account for parts of this variation...

33 CFR 334.78 - Rhode Island Sound, Atlantic Ocean, approximately 4.0 nautical miles due south of Lands End in...

Code of Federal Regulations, 2012 CFR

2012-07-01

... will consist of six inert drill mines each 16 inches in diameter and 5 feet long and one concrete sonar target 48 inches in diameter and 48 inches high located within the designated area. The sonar target will... sonar. Neither variable depth sonar devices or mechanical minesweeping operations will be utilized in...

Pl17 is a novel gene independent of known downy mildew resistance genes in the cultivated sunflower (Helianthus annuus L.)

USDA-ARS?s Scientific Manuscript database

Downy mildew (DM), caused by Plasmopara halstedii (Farl.) Berl. et de Toni, is one of the serious sunflower diseases in the world due to its high virulence and the variability of the pathogen. DM resistance in the USDA inbred line, HA 458, has been shown to be effective against all virulent races of...

Is Personality Fixed? Personality Changes as Much as "Variable" Economic Factors and More Strongly Predicts Changes to Life Satisfaction

ERIC Educational Resources Information Center

Boyce, Christopher J.; Wood, Alex M.; Powdthavee, Nattavudh

2013-01-01

Personality is the strongest and most consistent cross-sectional predictor of high subjective well-being. Less predictive economic factors, such as higher income or improved job status, are often the focus of applied subjective well-being research due to a perception that they can change whereas personality cannot. As such there has been limited…

A Study to Determine Non-Academic Traits of a Successful Student in an Open Learning Center Environment at John Wood Community College.

ERIC Educational Resources Information Center

Kronquist, Shirley; And Others

John Wood Community College's Open Learning Center (OLC) offers an alternative to traditional classroom approaches using one-to-one instruction, a competency-based learning format, and flexible scheduling. Due to concern over the high attrition rate in OLC courses, a study was conducted to identify the characteristics and variables contributing to…

Effect of Cryopreservation and Post-Cryopreservation Somatic Embryogenesis on the Epigenetic Fidelity of Cocoa (Theobroma cacao L.).

PubMed

Adu-Gyamfi, Raphael; Wetten, Andy; Marcelino Rodríguez López, Carlos

2016-01-01

While cocoa plants regenerated from cryopreserved somatic embryos can demonstrate high levels of phenotypic variability, little is known about the sources of the observed variability. Previous studies have shown that the encapsulation-dehydration cryopreservation methodology imposes no significant extra mutational load since embryos carrying high levels of genetic variability are selected against during protracted culture. Also, the use of secondary rather than primary somatic embryos has been shown to further reduce the incidence of genetic somaclonal variation. Here, the effect of in vitro conservation, cryopreservation and post-cryopreservation generation of somatic embryos on the appearance of epigenetic somaclonal variation were comparatively assessed. To achieve this we compared the epigenetic profiles, generated using Methylation Sensitive Amplified Polymorphisms, of leaves collected from the ortet tree and from cocoa somatic embryos derived from three in vitro conditions: somatic embryos, somatic embryos cryopreserved in liquid nitrogen and somatic embryos generated from cryoproserved somatic embryos. Somatic embryos accumulated epigenetic changes but these were less extensive than in those regenerated after storage in LN. Furthermore, the passage of cryopreserved embryos through another embryogenic stage led to further increase in variation. Interestingly, this detected variability appears to be in some measure reversible. The outcome of this study indicates that the cryopreservation induced phenotypic variability could be, at least partially, due to DNA methylation changes. Phenotypic variability observed in cryostored cocoa somatic-embryos is epigenetic in nature. This variability is partially reversible, not stochastic in nature but a directed response to the in-vitro culture and cryopreservation.

Effect of Cryopreservation and Post-Cryopreservation Somatic Embryogenesis on the Epigenetic Fidelity of Cocoa (Theobroma cacao L.)

PubMed Central

Adu-Gyamfi, Raphael; Wetten, Andy; Marcelino Rodríguez López, Carlos

2016-01-01

While cocoa plants regenerated from cryopreserved somatic embryos can demonstrate high levels of phenotypic variability, little is known about the sources of the observed variability. Previous studies have shown that the encapsulation-dehydration cryopreservation methodology imposes no significant extra mutational load since embryos carrying high levels of genetic variability are selected against during protracted culture. Also, the use of secondary rather than primary somatic embryos has been shown to further reduce the incidence of genetic somaclonal variation. Here, the effect of in vitro conservation, cryopreservation and post-cryopreservation generation of somatic embryos on the appearance of epigenetic somaclonal variation were comparatively assessed. To achieve this we compared the epigenetic profiles, generated using Methylation Sensitive Amplified Polymorphisms, of leaves collected from the ortet tree and from cocoa somatic embryos derived from three in vitro conditions: somatic embryos, somatic embryos cryopreserved in liquid nitrogen and somatic embryos generated from cryoproserved somatic embryos. Somatic embryos accumulated epigenetic changes but these were less extensive than in those regenerated after storage in LN. Furthermore, the passage of cryopreserved embryos through another embryogenic stage led to further increase in variation. Interestingly, this detected variability appears to be in some measure reversible. The outcome of this study indicates that the cryopreservation induced phenotypic variability could be, at least partially, due to DNA methylation changes. Key message: Phenotypic variability observed in cryostored cocoa somatic-embryos is epigenetic in nature. This variability is partially reversible, not stochastic in nature but a directed response to the in-vitro culture and cryopreservation. PMID:27403857

Signal enhancement due to high-Z nanofilm electrodes in parallel plate ionization chambers with variable microgaps.

PubMed

Brivio, Davide; Sajo, Erno; Zygmanski, Piotr

2017-12-01

We developed a method for measuring signal enhancement produced by high-Z nanofilm electrodes in parallel plate ionization chambers with variable thickness microgaps. We used a laboratory-made variable gap parallel plate ionization chamber with nanofilm electrodes made of aluminum-aluminum (Al-Al) and aluminum-tantalum (Al-Ta). The electrodes were evaporated on 1 mm thick glass substrates. The interelectrode air gap was varied from 3 μm to 1 cm. The gap size was measured using a digital micrometer and it was confirmed by capacitance measurements. The electric field in the chamber was kept between 0.1 kV/cm and 1 kV/cm for all the gap sizes by applying appropriate compensating voltages. The chamber was exposed to 120 kVp X-rays. The current was measured using a commercial data acquisition system with temporal resolution of 600 Hz. In addition, radiation transport simulations were carried out to characterize the dose, D(x), high-energy electron current, J(x), and deposited charge, Q(x), as a function of distance, x, from the electrodes. A deterministic method was selected over Monte Carlo due to its ability to produce results with 10 nm spatial resolution without stochastic uncertainties. Experimental signal enhancement ratio, SER(G) which we defined as the ratio of signal for Al-air-Ta to signal for Al-air-Al for each gap size, was compared to computations. The individual contributions of dose, electron current, and charge deposition to the signal enhancement were determined. Experimental signals matched computed data for all gap sizes after accounting for several contributions to the signal: (a) charge carrier generated via ionization due to the energy deposited in the air gap, D(x); (b) high-energy electron current, J(x), leaking from high-Z electrode (Ta) toward low-Z electrode (Al); (c) deposited charge in the air gap, Q(x); and (d) the decreased collection efficiency for large gaps (>~500 μm). Q(x) accounts for the electrons below 100 eV, which are regarded as stopped by the radiation transport code but which can move and form electron current in small gaps (<100 μm). While the total energy deposited in the air gap increases with gap size for both samples, the average high-energy current and deposited charge are moderately decreasing with the air gap. When gap sizes are smaller than ~20 μm, the contribution to signal from dose approaches zero while contributions from high-energy current and deposited charges give rise to an offset signal. The measured signal enhancement ratio (SER) was 40.0 ± 5.0 for the 3 μm gap and rapidly decreasing with gap size down to 9.9 ± 1.2 for the 21 μm gap and to 6.6 ± 0.3 for the 100 μm gap. The uncertainties in SER were mostly due to uncertainties in gap size and data acquisition system. We developed an experimental method to determine the signal enhancement due to high-Z nanolayers in parallel plate ionization chambers with micrometer spatial resolution. As the water-equivalent thicknesses of these air gaps are 3 nm to 10 μm, the method may also be applicable for nanoscopic spatial resolution of other gap materials. The method may be extended to solid insulator materials with low Z. © 2017 American Association of Physicists in Medicine.

The Acute Effects of Aerobic Exercise on Cognitive Flexibility and Task-Related Heart Rate Variability in Children With ADHD and Healthy Controls.

PubMed

Ludyga, Sebastian; Gerber, Markus; Mücke, Manuel; Brand, Serge; Weber, Peter; Brotzmann, Mark; Pühse, Uwe

2018-02-01

To investigate cognitive flexibility and task-related heart rate variability following moderately intense aerobic exercise and after watching a video in both children with ADHD and healthy controls. Using a cross-over design, participants completed cognitive assessments following exercise and a physically inactive control condition. Behavioral performance was assessed using the Alternate Uses task. Heart rate variability was recorded via electrocardiography during the cognitive task. The statistical analysis revealed that in comparison with the control condition, both groups showed higher cognitive flexibility following aerobic exercise. Moreover, decreased low frequency and high frequency power was observed in the exercise condition. The findings suggest that exercise elicits similar benefits for cognitive flexibility in children with ADHD and healthy controls, partly due to an increase in arousal induced by parasympathetic withdrawal.

A Link between Variability of the Semidiurnal Tide and Planetary Waves in the Opposite Hemisphere

NASA Technical Reports Server (NTRS)

Smith, Anne K.; Pancheva, Dora V.; Mitchell, Nicholas J.; Marsh, Daniel R.; Russell, James M., III; Mlynczak, Martin G.

2007-01-01

Horizontal wind observations over four years from the meteor radar at Esrange (68 deg N) are analyzed to determine the variability of the semidiurnal tide. Simultaneous global observations of temperature and geopotential from the SABER satellite instrument are used to construct time series of planetary wave amplitudes and geostrophic mean zonal wind. During NH summer and fall, the temporal variability of the semidiurnal tide at Esrange is found to be well correlated with the amplitude of planetary wavenumber 1 in the stratosphere in high southern latitudes (i.e., in the opposite hemisphere). The correlations indicate that a significant part of the tidal variations at Esrange is due to dynamical interactions in the Southern Hemisphere. Other times of the year do not indicate a corresponding robust correlation pattern for the Esrange tides over multiple years.

The X-ray spectra of the BL Lacertae objects PKS 0548 - 322 and 3C 66A

NASA Technical Reports Server (NTRS)

Maccacaro, T.; Maccagni, D.; Tarenghi, M.

1983-01-01

Einstein Observatory simultaneous imaging proportional counter and monitor proportional counter data are combined in order to derive the energy spectra of the BL Lac objects PKS 0548-322 and 3C 66A between 0.2 and 10 keV. While the latter is found to be variable in both intensity and spectral shape, the former, although constant in the present data, is found to have experienced a spectrum variation in view of results from other experiments. Attention is given to the implications of flux and spectral variability in BL Lac objects for models of X-ray emission mechanisms. It is suggested that the wide spread of the spectral index distribution is due to the detection of the highly variable synchrotron-produced X-rays that are generally undetected in QSOs.

Failure of Cleaning Verification in Pharmaceutical Industry Due to Uncleanliness of Stainless Steel Surface.

PubMed

Haidar Ahmad, Imad A; Blasko, Andrei

2017-08-11

The aim of this work is to identify the parameters that affect the recovery of pharmaceutical residues from the surface of stainless steel coupons. A series of factors were assessed, including drug product spike levels, spiking procedure, drug-excipient ratios, analyst-to-analyst variability, intraday variability, and cleaning procedure of the coupons. The lack of a well-defined procedure that consistently cleaned the coupon surface was identified as the major contributor to low and variable recoveries. Assessment of cleaning the surface of the coupons with clean-in-place solutions (CIP) gave high recovery (>90%) and reproducible results (Srel≤4%) regardless of the conditions that were assessed previously. The approach was successfully applied for cleaning verification of small molecules (MW <1,000 Da) as well as large biomolecules (MW up to 50,000 Da).

Potential for negative emissions of greenhouse gases (CO2, CH4 and N2O) through coastal peatland re-establishment: Novel insights from high frequency flux data at meter and kilometer scales

NASA Astrophysics Data System (ADS)

Windham-Myers, Lisamarie; Bergamaschi, Brian; Anderson, Frank; Knox, Sara; Miller, Robin; Fujii, Roger

2018-04-01

High productivity temperate wetlands that accrete peat via belowground biomass (peatlands) may be managed for climate mitigation benefits due to their global distribution and notably negative emissions of atmospheric carbon dioxide (CO2) through rapid storage of carbon (C) in anoxic soils. Net emissions of additional greenhouse gases (GHG)—methane (CH4) and nitrous oxide (N2O)—are more difficult to predict and monitor due to fine-scale temporal and spatial variability, but can potentially reverse the climate mitigation benefits resulting from CO2 uptake. To support management decisions and modeling, we collected continuous 96 hour high frequency GHG flux data for CO2, CH4 and N2O at multiple scales—static chambers (1 Hz) and eddy covariance (10 Hz)—during peak productivity in a well-studied, impounded coastal peatland in California’s Sacramento Delta with high annual rates of C fluxes, sequestering 2065 ± 150 g CO2 m‑2 y‑1 and emitting 64.5 ± 2.4 g CH4 m‑2 y‑1. Chambers (n = 6) showed strong spatial variability along a hydrologic gradient from inlet to interior plots. Daily (24 hour) net CO2 uptake (NEE) was highest near inlet locations and fell dramatically along the flowpath (‑25 to ‑3.8 to +2.64 g CO2 m‑2 d‑1). In contrast, daily net CH4 flux increased along the flowpath (0.39 to 0.62 to 0.88 g CH4 m‑2 d‑1), such that sites of high daily CO2 uptake were sites of low CH4 emission. Distributed, continuous chamber data exposed five novel insights, and at least two important datagaps for wetland GHG management, including: (1) increasing dominance of CH4 ebullition fluxes (15%–32% of total) along the flowpath and (2) net negative N2O flux across all sites as measured during a 4 day period of peak biomass (‑1.7 mg N2O m‑2 d‑1 0.51 g CO2 eq m‑2 d‑1). The net negative emissions of re-established peat-accreting wetlands are notably high, but may be poorly estimated by models that do not consider within-wetland spatial variability due to water flowpaths.

Fouling of microfiltration membranes by flowback and produced waters from the Marcellus shale gas play.

PubMed

Xiong, Boya; Zydney, Andrew L; Kumar, Manish

2016-08-01

There is growing interest in possible options for treatment or reuse of flowback and produced waters from natural gas processing. Here we investigated the fouling characteristics during microfiltration of different flowback and produced waters from hydraulic fracturing sites in the Marcellus shale. All samples caused severe and highly variable fouling, although there was no direct correlation between the fouling rate and total suspended solids, turbidity, or total organic carbon. Furthermore, the fouling of water after prefiltration through a 0.2 μm membrane was also highly variable. Low fouling seen with prefiltered water was mainly due to removal of submicron particles 0.4-0.8 μm during prefiltration. High fouling seen with prefiltered water was mainly caused by a combination of hydrophobic organics and colloidal particles <100 nm in size (quantified by transmission electron microscopy) that passed through the prefiltration membranes. The small colloidal particles were highly stable, likely due to the surfactants and other organics present in the fracking fluids. The colloid concentration was as high as 10(11) colloids/ml, which is more than 100 times greater than that in typical seawater. Furthermore, these colloids were only partially removed by MF, causing substantial fouling during a subsequent ultrafiltration. These results clearly show the importance of organics and colloidal material in membrane fouling caused by flowback and produced waters, which is of critical importance in the development of more sustainable treatment strategies in natural gas processing. Copyright © 2016 Elsevier Ltd. All rights reserved.

Environmental variation and macrofauna response in a coastal area influenced by land runoff

NASA Astrophysics Data System (ADS)

Akoumianaki, Ioanna; Papaspyrou, Sokratis; Kormas, Konstantinos Ar.; Nicolaidou, Artemis

2013-11-01

Macrofauna community interactions with environmental variables in the water column (salinity, temperature, turbidity, transparency, suspended particulate matter, particulate organic matter, choloroplastic pigments) and in the sediment (granulometric variables, organic carbon and pigments) were investigated in a coastal area with high land runoff due to riverine and temporary stream discharges (Greece, Aegean Sea, Maliakos Gulf). Samples were taken along a distance-depositional gradient from the river mouth to the open sea at eight stations, at times of different precipitation regime from August 2000 to May 2001. The physical variables, such as transparency and median grain size, generally increased seawards, and parallelled the depositional gradient as opposed to measures of food inputs and hydrodynamic regime. High environmental heterogeneity was observed during peak precipitation. The total number of species increased seawards and from August (122 species) to May (170 species). Maximum abundance also increased from August (4953 m-2) to May (10,220 individuals m-2), irrespective of distance from river mouth. Species belonging to different functional groups, as to recolonization, feeding, motility and substrate preferences, coexisted at all times indicating high functional diversity. Non-parametric multivariate regression showed that at times of low, rising and falling precipitation 78-81% of community variation was explained by environmental variables, indicating that macrofauna distribution and species composition respond to food inputs and sediment characteristics. During peak land runoff the community-environment relationship weakened (57% of the variability explained). The diversity of functional traits of the most abundant species indicates that the macrofauna community can absorb the impact of increased turbidity, sedimentation and current-driven dispersion. The study offers baseline information for the integrated coastal zone management in microtidal areas with high land runoff under Mediterranean-type climate conditions. During peak land runoff the community-environment relationship weakened (57% of the variability explained) whilst species distribution ranges increased. The study shows that the functional diversity in the study area prior to high discharge period enable macrofauna community to absorb the impact of increased turbidity, sedimentation and current-driven dispersion. The study offers baseline information for the impact of high land runoff in microtidal areas under Mediterranean-type climate conditions.

Seasonal Variability in Regional Ice Flow Due to Meltwater Injection Into the Shear Margins of Jakobshavn Isbræ

NASA Astrophysics Data System (ADS)

Cavanagh, J. P.; Lampkin, D. J.; Moon, T.

2017-12-01

The impact of meltwater injection into the shear margins of Jakobshavn Isbræ via drainage from water-filled crevasses on ice flow is examined. We use Landsat-8 Operational Land Imager panchromatic, high-resolution imagery to monitor the spatiotemporal variability of seven water-filled crevasse ponds during the summers of 2013 to 2015. The timing of drainage from water-filled crevasses coincides with an increase of 2 to 20% in measured ice velocity beyond Jakobshavn Isbræ shear margins, which we define as extramarginal ice velocity. Some water-filled crevasse groups demonstrate multiple drainage events within a single melt season. Numerical simulations show that hydrologic shear weakening due to water-filled crevasse drainage can accelerate extramarginal flow by as much as 35% within 10 km of the margins and enhance mass flux through the shear margins by 12%. This work demonstrates a novel mechanism through which surface melt can influence regional ice flow.

Consequences of sea level variability and sea level rise for Cuban territory

NASA Astrophysics Data System (ADS)

Hernández, M.; Martínez, C. A.; Marzo, O.

2015-03-01

The objective of the present paper was to determine a first approximation of coastal zone flooding by 2100, taking into account the more persistent processes of sea level variability and non-accelerated linear sea level rise estimation to assess the main impacts. The annual linear rate of mean sea level rise in the Cuban archipelago, obtained from the longest tide gauge records, has fluctuated between 0.005 cm/year at Casilda and 0.214 cm/year at Siboney. The main sea level rise effects for the Cuban coastal zone due to climate change and global warming are shown. Monthly and annual mean sea level anomalies, some of which are similar to or higher than the mean sea level rise estimated for halfway through the present century, reinforce the inland seawater penetration due to the semi-daily high tide. The combination of these different events will result in the loss of goods and services, and require expensive investments for adaption.

Twentieth century bipolar seesaw of the Arctic and Antarctic surface air temperatures

NASA Astrophysics Data System (ADS)

Chylek, Petr; Folland, Chris K.; Lesins, Glen; Dubey, Manvendra K.

2010-04-01

Understanding the phase relationship between climate changes in the Arctic and Antarctic regions is essential for our understanding of the dynamics of the Earth's climate system. In this paper we show that the 20th century de-trended Arctic and Antarctic temperatures vary in anti-phase seesaw pattern - when the Arctic warms the Antarctica cools and visa versa. This is the first time that a bi-polar seesaw pattern has been identified in the 20th century Arctic and Antarctic temperature records. The Arctic (Antarctic) de-trended temperatures are highly correlated (anti-correlated) with the Atlantic Multi-decadal Oscillation (AMO) index suggesting the Atlantic Ocean as a possible link between the climate variability of the Arctic and Antarctic regions. Recent accelerated warming of the Arctic results from a positive reinforcement of the linear warming trend (due to an increasing concentration of greenhouse gases and other possible forcings) by the warming phase of the multidecadal climate variability (due to fluctuations of the Atlantic Ocean circulation).

Squeezing of Particle Distributions by Expanding Magnetic Turbulence and Space Weather Variability

NASA Astrophysics Data System (ADS)

Ruffolo, D. J.; Tooprakai, P.; Seripienlert, A.; Chuychai, P.; Matthaeus, W. H.

2014-12-01

Among the space weather effects due to gradual solar storms, greatly enhanced high-energy ion fluxes can cause radiation damage to satellites, spacecraft, and astronauts, which motivates examination of the transport of high-energy solar ions to Earth orbit. Ions of low kinetic energy (up to ˜2sim 2 MeV/nucleon) from impulsive solar events exhibit abrupt changes due to filamentation of magnetic connection from the Sun, indicating that anisotropic, field-aligned magnetic flux tube-like structures persist to Earth orbit. By employing a corresponding spherical two-component model of Alfv'enic (slab) and 2D magnetic fluctuations to trace simulated trajectories in the solar wind, we show that the distribution of high-energy (E≥1Egeq1 GeV) protons from gradual solar events is squeezed toward magnetic flux structures with a specific polarity due to the conical shape of the flux structures, which results from the expanding flow of the solar wind. It is difficult to observationally determine what polarity of flux structure the Earth is in at a given time, so this transport phenomenon contributes to event-to-event variability in ground level enhancements of GeV-range ions from solar storms, presenting a fundamental uncertainty in space weather prediction. Partially supported by the Thailand Research Fund, a Postdoctoral Fellowship from the Thailand Center of Excellence in Physics, a Research Fellowship from the Faculty of Science, Mahidol University, the U.S. NSF (AGS-1063439 and SHINE AGS-1156094), NASA (Heliophysics Theory NNX08AI47G & NNX11AJ44G), and the Solar Probe Plus/ISIS project. KEYWORDS: [7807] SPACE PLASMA PHYSICS / Charged particle motion and acceleration, [7863] SPACE PLASMA PHYSICS / Turbulence, [2118] INTERPLANETARY PHYSICS / Energetic particles, solar, [7984] SPACE WEATHER / Space radiation environment

Functional variability of habitats within the Sacramento-San Joaquin Delta: Restoration implications

USGS Publications Warehouse

Lucas, L.V.; Cloern, J.E.; Thompson, J.K.; Monsen, N.E.

2002-01-01

We have now entered an era of large-scale attempts to restore ecological functions and biological communities in impaired ecosystems. Our knowledge base of complex ecosystems and interrelated functions is limited, so the outcomes of specific restoration actions are highly uncertain. One approach for exploring that uncertainty and anticipating the range of possible restoration outcomes is comparative study of existing habitats similar to future habitats slated for construction. Here we compare two examples of one habitat type targeted for restoration in the Sacramento-San Joaquin River Delta. We compare one critical ecological function provided by these shallow tidal habitats - production and distribution of phytoplankton biomass as the food supply to pelagic consumers. We measured spatial and short-term temporal variability of phytoplankton biomass and growth rate and quantified the hydrodynamic and biological processes governing that variability. Results show that the production and distribution of phytoplankton biomass can be highly variable within and between nearby habitats of the same type, due to variations in phytoplankton sources, sinks, and transport. Therefore, superficially similar, geographically proximate habitats can function very differently, and that functional variability introduces large uncertainties into the restoration process. Comparative study of existing habitats is one way ecosystem science can elucidate and potentially minimize restoration uncertainties, by identifying processes shaping habitat functionality, including those that can be controlled in the restoration design.

High-resolution IP25-based reconstruction of sea-ice variability in the western North Pacific and Bering Sea during the past 18,000 years

NASA Astrophysics Data System (ADS)

Méheust, Marie; Stein, Ruediger; Fahl, Kirsten; Max, Lars; Riethdorf, Jan-Rainer

2016-04-01

Due to its strong influence on heat and moisture exchange between the ocean and the atmosphere, sea ice is an essential component of the global climate system. In the context of its alarming decrease in terms of concentration, thickness and duration, understanding the processes controlling sea-ice variability and reconstructing paleo-sea-ice extent in polar regions have become of great interest for the scientific community. In this study, for the first time, IP25, a recently developed biomarker sea-ice proxy, was used for a high-resolution reconstruction of the sea-ice extent and its variability in the western North Pacific and western Bering Sea during the past 18,000 years. To identify mechanisms controlling the sea-ice variability, IP25 data were associated with published sea-surface temperature as well as diatom and biogenic opal data. The results indicate that a seasonal sea-ice cover existed during cold periods (Heinrich Stadial 1 and Younger Dryas), whereas during warmer intervals (Bølling-Allerød and Holocene) reduced sea ice or ice-free conditions prevailed in the study area. The variability in sea-ice extent seems to be linked to climate anomalies and sea-level changes controlling the oceanographic circulation between the subarctic Pacific and the Bering Sea, especially the Alaskan Stream injection though the Aleutian passes.

Non-equilibrium Green's functions study of discrete dopants variability on an ultra-scaled FinFET

DOE Office of Scientific and Technical Information (OSTI.GOV)

Valin, R., E-mail: r.valinferreiro@swansea.ac.uk; Martinez, A., E-mail: a.e.Martinez@swansea.ac.uk; Barker, J. R., E-mail: john.barker@glasgow.ac.uk

In this paper, we study the effect of random discrete dopants on the performance of a 6.6 nm channel length silicon FinFET. The discrete dopants have been distributed randomly in the source/drain region of the device. Due to the small dimensions of the FinFET, a quantum transport formalism based on the non-equilibrium Green's functions has been deployed. The transfer characteristics for several devices that differ in location and number of dopants have been calculated. Our results demonstrate that discrete dopants modify the effective channel length and the height of the source/drain barrier, consequently changing the channel control of the charge. Thismore » effect becomes more significant at high drain bias. As a consequence, there is a strong effect on the variability of the on-current, off-current, sub-threshold slope, and threshold voltage. Finally, we have also calculated the mean and standard deviation of these parameters to quantify their variability. The obtained results show that the variability at high drain bias is 1.75 larger than at low drain bias. However, the variability of the on-current, off-current, and sub-threshold slope remains independent of the drain bias. In addition, we have found that a large source to drain current by tunnelling current occurs at low gate bias.« less

Seasonal variability of convectively coupled equatorial waves (CCEWs) in recent high-top CMIP5 models

NASA Astrophysics Data System (ADS)

Zakaria, Dzaki; Lubis, Sandro W.; Setiawan, Sonni

2018-05-01

Tropical weather system is controlled by periodic atmospheric disturbances ranging from daily to subseasonal time scales. One of the most prominent atmospheric disturbances in the tropics is convectively coupled equatorial waves (CCEWs). CCEWs are excited by latent heating due to a large-scale convective system and have a significant influence on weather system. They include atmospheric equatorial Kelvin wave, Mixed Rossby Gravity (MRG) wave, Equatorial Rossby (ER) wave and Tropical Depression (TD-type) wave. In this study, we will evaluate the seasonal variability of CCEWs activity in nine high-top CMIP5 models, including their spatial distribution in the troposphere. Our results indicate that seasonal variability of Kelvin waves is well represented in MPI-ESM-LR and MPI-ESM-MR, with maximum activity occurring during boreal spring. The seasonal variability of MRG waves is well represented in CanESM2, HadGEM2-CC, IPSL-CM5A-LR and IPSL-CM5A-MR, with maximum activity observed during boreal summer. On the other hand, ER waves are well captured by IPSL-CM5A-LR and IPSL-CM5A-MR and maximize during boreal fall; while TD-type waves, with maximum activity observed during boreal summer, are well observed in CanESM2, HadGEM2-CC, IPSL-CM5A-LR and IPSL-CM5A-MR. Our results indicate that the skill of CMIP5 models in representing seasonal variability of CCEWs highly depends on the convective parameterization and the spatial or vertical resolution used by each model.

The GISS global climate-middle atmosphere model. II - Model variability due to interactions between planetary waves, the mean circulation and gravity wave drag

NASA Technical Reports Server (NTRS)

Rind, D.; Suozzo, R.; Balachandran, N. K.

1988-01-01

The variability which arises in the GISS Global Climate-Middle Atmosphere Model on two time scales is reviewed: interannual standard deviations, derived from the five-year control run, and intraseasonal variability as exemplified by statospheric warnings. The model's extratropical variability for both mean fields and eddy statistics appears reasonable when compared with observations, while the tropical wind variability near the stratopause may be excessive possibly, due to inertial oscillations. Both wave 1 and wave 2 warmings develop, with connections to tropospheric forcing. Variability on both time scales results from a complex set of interactions among planetary waves, the mean circulation, and gravity wave drag. Specific examples of these interactions are presented, which imply that variability in gravity wave forcing and drag may be an important component of the variability of the middle atmosphere.

Scheduling Jobs and a Variable Maintenance on a Single Machine with Common Due-Date Assignment

PubMed Central

Wan, Long

2014-01-01

We investigate a common due-date assignment scheduling problem with a variable maintenance on a single machine. The goal is to minimize the total earliness, tardiness, and due-date cost. We derive some properties on an optimal solution for our problem. For a special case with identical jobs we propose an optimal polynomial time algorithm followed by a numerical example. PMID:25147861

Genetic variability in maned wolf based on heterologous short-tandem repeat markers from domestic dog.

PubMed

Salim, D C; Akimoto, A A; Carvalho, C B; Oliveira, S F; Grisolia, C K; Moreira, J R; Klautau-Guimarães, M N

2007-06-20

The maned wolf (Chrysocyon brachyurus) is the largest South American canid. Habitat loss and fragmentation, due to agricultural expansion and predatory hunting, are the main threats to this species. It is included in the official list of threatened wildlife species in Brazil, and is also protected by IUCN and CITES. Highly variable genetic markers such as microsatellites have the potential to resolve genetic relationships at all levels of the population structure (among individuals, demes or metapopulations) and also to identify the evolutionary unit for strategies for the conservation of the species. Tests were carried out to verify whether a class of highly polymorphic tetranucleotide repeats described for the domestic dog effectively amplifies DNA in the maned wolf. All five loci studied were amplified; however, one of these, was shown to be monomorphic in 69 maned wolf samples. The average allele number and estimated heterozygosity per polymorphic locus were 4.3 and 67%, respectively. The genetic variability found for this species, which is considered threatened with extinction, showed similar results when compared to studies of other canids.

Long-wave Irradiance Measurement and Modeling during Snowmelt, a Case Study in the Yukon Territory, Canada

NASA Astrophysics Data System (ADS)

Sicart, J.; Essery, R.; Pomeroy, J.

2004-12-01

At high latitudes, long-wave radiation emitted by the atmosphere and solar radiation can provide similar amounts of energy for snowmelt due to the low solar elevation and the high albedo of snow. This paper investigates temporal and spatial variations of long-wave irradiance at the snow surface in an open sub-Arctic environment. Measurements were conducted in the Wolf Creek Research Basin, Yukon Territory, Canada (60°36'N, 134°57'W) during the springs of 2002, 2003 and 2004. The main causes of temporal variability are air temperature and cloud cover, especially in the beginning of the melting period when the atmosphere is still cold. Spatial variability was investigated through a sensitivity study to sky view factors and to temperatures of surrounding terrain. The formula of Brutsaert gives a useful estimation of the clear-sky irradiance at hourly time steps. Emission by clouds was parameterized at the daily time scale from the atmospheric attenuation of solar radiation. The inclusion of air temperature variability does not much improve the calculation of cloud emission.

Rapid change of chromomeric and pairing patterns of polytene chromosome tips in D. melanogaster: migration of polytene-nonpolytene transition zone?

PubMed

Roberts, P A

1979-07-01

The high variability of chromomeric patterns in near-terminal regions of polytene chromosome arms has been explored in a number of races, strains and hybrids of Drosophila melanogaster. Traditional explanations for tip differences between strains (differential compaction of chromatin, somatic or germinal deletion) are examined and, in the light of the reported observations, rejected. The range of polytene tip variability and rates of change in wild races are greater than has been supposed: strains formerly considered to be terminally deleted appear to gain terminal bands; others, formerly considered normal, appear to have lost them. Strains with high cell-to-cell tip variability are also described. Cell-to-cell variations, as well as much of the observed rapid changes in tip appearance, are probably due to heritable differences in the location of an abrupt transition zone between polytene and nonpolytene chromatin. A quantitative relationship between the amount of certain subterminal bands present and the frequency of tip association of nonhomologous chromosomes is shown and its possible significance for chromosome is shown and its possible for chromosome pairing discussed.

On the value of aiming high: the causes and consequences of ambition.

PubMed

Judge, Timothy A; Kammeyer-Mueller, John D

2012-07-01

Ambition is a commonly mentioned but poorly understood concept in social science research. We sought to contribute to understanding of the concept by developing and testing a model in which ambition is a middle-level trait (Cantor, 1990)-predicted by more distal characteristics but, due to its teleological nature, more proximally situated to predict career success. A 7-decade longitudinal sample of 717 high-ability individuals from the Terman life-cycle study (Terman, Sears, Cronbach, & Sears, 1989) was used in the current study. Results indicated that ambition was predicted by individual differences-conscientiousness, extraversion, neuroticism, and general mental ability-and a socioeconomic background variable: parents' occupational prestige. Ambition, in turn, was positively related to educational attainment, occupation prestige, and income. Ambition had significant total effects with all of the endogenous variables except mortality. Overall, the results support the thesis that ambition is a middle-level trait-related to but distinct from more distal individual difference variables-that has meaningful effects on career success. (PsycINFO Database Record (c) 2012 APA, all rights reserved).

Variability in venom volume, flow rate and duration in defensive stings of five scorpion species.

PubMed

van der Meijden, Arie; Coelho, Pedro; Rasko, Mykola

2015-06-15

Scorpions have been shown to control their venom usage in defensive encounters, depending on the perceived threat. Potentially, the venom amount that is injected could be controlled by reducing the flow speed, the flow duration, or both. We here investigated these variables by allowing scorpions to sting into an oil-filled chamber, and recording the accreting venom droplets with high-speed video. The size of the spherical droplets on the video can then be used to calculate their volume. We recorded defensive stings of 20 specimens representing 5 species. Significant differences in the flow rate and total expelled volume were found between species. These differences are likely due to differences in overall size between the species. Large variation in both venom flow speed and duration are described between stinging events of single individuals. Both venom flow rate and flow duration correlate highly with the total expelled volume, indicating that scorpions may control both variables in order to achieve a desired end volume of venom during a sting. Copyright © 2015 Elsevier Ltd. All rights reserved.

Thermal radiation and heat generation/absorption aspects in third grade magneto-nanofluid over a slendering stretching sheet with Newtonian conditions

NASA Astrophysics Data System (ADS)

Qayyum, Sajid; Hayat, Tasawar; Alsaedi, Ahmed

2018-05-01

Mathematical modeling for magnetohydrodynamic (MHD) radiative flow of third grade nano-material bounded by a nonlinear stretching sheet with variable thickness is introduced. The sheet moves with nonlinear velocity. Definitions of thermal radiation and heat generation/absorption are utilized in the energy expression. Intention in present investigation is to develop a model for nanomaterial comprising Brownian motion and thermophoresis phenomena. Newtonian conditions for heat and mass species are imposed. Governing equations of the locally similar flow are attempted through a homotopic technique and behaviors of involved variables on the flow fields are displayed graphically. It is revealed that increasing values of thermal conjugate variable corresponds to high temperature. Numerical investigation are explored to obtain the results of skin friction coefficient and local Nusselt and Sherwood numbers. It is revealed that velocity field reduces in the frame of magnetic variable while reverse situation is observed due to mixed convection parameter. Here qualitative behaviors of thermal field and heat transfer rate are opposite for thermophoresis variable. Moreover nanoparticle concentration and local Sherwood number via Brownian motion parameter are opposite.

Analysis Of Irtf Spex Near-infrared Observations Of Uranus: Aerosol Optical Properties And Latitudinally Variable Methane

NASA Astrophysics Data System (ADS)

Tice, Dane; Irwin, P. G. J.; Fletcher, L. N.; Teanby, N. A.; Hurley, J.; Orton, G. S.; Davis, G. R.

2012-10-01

We present results from the analysis of near-infrared spectra of Uranus observed in August 2009 with the SpeX spectrograph at the NASA Infrared Telescope Facility (IRTF). Spectra range from 0.8 to 1.8 μm at a spatial resolution of 0.5” and a spectral resolution of R = 1,200. This data is particularly well-suited to characterize the optical properties of aerosols in the Uranian stratosphere and upper troposphere. This is in part due to its coverage shortward of 1.0 μm where methane absorption, which dominates the features in the Uranian near-infrared spectrum, weakens slightly. Another particularly useful aspect of the data is it’s specific, highly spectrally resolved (R > 4,000) coverage of the collision-induced hydrogen quadrupole absorption band at 825 nm, enabling us to differentiate between methane abundance and cloud opacity. An optimal-estimation retrieval code, NEMESIS, is used to analyze the spectra, and atmospheric models are developed that represent good agreement with data in the full spectral range analyzed. Aerosol single-scattering albedos that reveal a strong wavelength dependence will be discussed. Additionally, an analysis of latitudinal methane variability is undertaken, utilizing two methods of analysis. First, a reflectance study from locations along the central meridian is undertaken. The spectra from these locations are centered around 825 nm, where the collision-induced absorption feature of hydrogen is utilized to distinguish between latitudinal changes in the spectrum due to aerosol opacity and those due to methane variability. Secondly, high resolution retrievals from 0.8 - 0.9 μm portion of the spectrum and spectral resolutions between R = 4,000 and 4,500 are used to make the same distinction. Both methods will be compared and discussed, as will their indications supporting a methane enrichment in the equatorial region of the planet.

Bark beetle-induced tree mortality alters stand energy budgets due to water budget changes

NASA Astrophysics Data System (ADS)

Reed, David E.; Ewers, Brent E.; Pendall, Elise; Frank, John; Kelly, Robert

2018-01-01

Insect outbreaks are major disturbances that affect a land area similar to that of forest fires across North America. The recent mountain pine bark beetle ( D endroctonus ponderosae) outbreak and its associated blue stain fungi ( Grosmannia clavigera) are impacting water partitioning processes of forests in the Rocky Mountain region as the spatially heterogeneous disturbance spreads across the landscape. Water cycling may dramatically change due to increasing spatial heterogeneity from uneven mortality. Water and energy storage within trees and soils may also decrease, due to hydraulic failure and mortality caused by blue stain fungi followed by shifts in the water budget. This forest disturbance was unique in comparison to fire or timber harvesting because water fluxes were altered before significant structural change occurred to the canopy. We investigated the impacts of bark beetles on lodgepole pine ( Pinus contorta) stand and ecosystem level hydrologic processes and the resulting vertical and horizontal spatial variability in energy storage. Bark beetle-impacted stands had on average 57 % higher soil moisture, 1.5 °C higher soil temperature, and 0.8 °C higher tree bole temperature over four growing seasons compared to unimpacted stands. Seasonal latent heat flux was highly correlated with soil moisture. Thus, high mortality levels led to an increase in ecosystem level Bowen ratio as sensible heat fluxes increased yearly and latent heat fluxes varied with soil moisture levels. Decline in canopy biomass (leaf, stem, and branch) was not seen, but ground-to-atmosphere longwave radiation flux increased, as the ground surface was a larger component of the longwave radiation. Variability in soil, latent, and sensible heat flux and radiation measurements increased during the disturbance. Accounting for stand level variability in water and energy fluxes will provide a method to quantify potential drivers of ecosystem processes and services as well as lead to greater confidence in measurements for all dynamic disturbances.

Quantitative variability of renewable energy resources in Norway

NASA Astrophysics Data System (ADS)

Christakos, Konstantinos; Varlas, George; Cheliotis, Ioannis; Aalstad, Kristoffer; Papadopoulos, Anastasios; Katsafados, Petros; Steeneveld, Gert-Jan

2017-04-01

Based on European Union (EU) targets for 2030, the share of renewable energy (RE) consumption should be increased at 27%. RE resources such as hydropower, wind, wave power and solar power are strongly depending on the chaotic behavior of the weather conditions and climate. Due to this dependency, the prediction of the spatiotemporal variability of the RE resources is more crucial factor than in other energy resources (i.e. carbon based energy). The fluctuation of the RE resources can affect the development of the RE technologies, the energy grid, supply and prices. This study investigates the variability of the potential RE resources in Norway. More specifically, hydropower, wind, wave, and solar power are quantitatively analyzed and correlated with respect to various spatial and temporal scales. In order to analyze the diversities and their interrelationships, reanalysis and observational data of wind, precipitation, wave, and solar radiation are used for a quantitative assessment. The results indicate a high variability of marine RE resources in the North Sea and the Norwegian Sea.

Interannual and cyclone-driven variability in phytoplankton communities of a tropical coastal lagoon.

PubMed

Srichandan, Suchismita; Kim, Ji Yoon; Kumar, Abhishek; Mishra, Deepak R; Bhadury, Punyasloke; Muduli, Pradipta R; Pattnaik, Ajit K; Rastogi, Gurdeep

2015-12-15

One of the main challenges in phytoplankton ecology is to understand their variability at different spatiotemporal scales. We investigated the interannual and cyclone-derived variability in phytoplankton communities of Chilika, the largest tropical coastal lagoon in Asia and the underlying mechanisms in relation to environmental forcing. Between July 2012 and June 2013, Cyanophyta were most prolific in freshwater northern region of the lagoon. A category-5 very severe cyclonic storm (VSCS) Phailin struck the lagoon on 12th October 2013 and introduced additional variability into the hydrology and phytoplankton communities. Freshwater Cyanophyta further expanded their territory and occupied the northern as well as central region of the lagoon. Satellite remote sensing imagery revealed that the phytoplankton biomass did not change much due to high turbidity prevailing in the lagoon after Phailin. Modeling analysis of species-salinity relationship identified specific responses of phytoplankton taxa to the different salinity regime of lagoon. Copyright © 2015 Elsevier Ltd. All rights reserved.

The no-show patient in the model family practice unit.

PubMed

Dervin, J V; Stone, D L; Beck, C H

1978-12-01

Appointment breaking by patients causes problems for the physician's office. Patients who neither keep nor cancel their appointments are often referred to as "no shows." Twenty variables were identified as potential predictors of no-show behavior. These predictors were applied to 291 Family Practice Center patients during a one-month study in April 1977. A discriminant function and multiple regression procedure were utilized ascertain the predictability of the selected variables. Predictive accuracy of the variables was 67.4 percent compared to the presently utilized constant predictor technique, which is 73 percent accurate. Modification of appointment schedules based upon utilization of the variables studies as predictors of show/no-show behavior does not appear to be an effective strategy in the Family Practice Center of the Community Hospital of Sonoma County, Santa Rosa, due to the high proportion of patients who do, in fact, show. In clinics with lower show rates, the technique may prove to be an effective strategy.

Year-to-year variations in annual average indoor 222Rn concentrations.

PubMed

Martz, D E; Rood, A S; George, J L; Pearson, M D; Langner, G H

1991-09-01

Annual average indoor 222Rn concentrations in 40 residences in and around Grand Junction, CO, have been measured repeatedly since 1984 using commercial alpha-track monitors (ATM) deployed for successive 12-mo time periods. Data obtained provide a quantitative measure of the year-to-year variations in the annual average Rn concentrations in these structures over this 6-y period. A mean coefficient of variation of 25% was observed for the year-to-year variability of the measurements at 25 sampling stations for which complete data were available. Individual coefficients of variation at the various stations ranged from a low of 7.7% to a high of 51%. The observed mean coefficient of variation includes contributions due to the variability in detector response as well as the true year-to-year variation in the annual average Rn concentrations. Factoring out the contributions from the measured variability in the response of the detectors used, the actual year-to-year variability of the annual average Rn concentrations was approximately 22%.

Gamma-Ray Burst Prompt Emission Light Curves and Power Density Spectra in the ICMART Model

NASA Astrophysics Data System (ADS)

Zhang, Bo; Zhang, Bing

2014-02-01

In this paper, we simulate the prompt emission light curves of gamma-ray bursts (GRBs) within the framework of the Internal-Collision-induced MAgnetic Reconnection and Turbulence (ICMART) model. This model applies to GRBs with a moderately high magnetization parameter σ in the emission region. We show that this model can produce highly variable light curves with both fast and slow components. The rapid variability is caused by many locally Doppler-boosted mini-emitters due to turbulent magnetic reconnection in a moderately high σ flow. The runaway growth and subsequent depletion of these mini-emitters as a function of time define a broad slow component for each ICMART event. A GRB light curve is usually composed of multiple ICMART events that are fundamentally driven by the erratic GRB central engine activity. Allowing variations of the model parameters, one is able to reproduce a variety of light curves and the power density spectra as observed.

Characterizing the chaotic nature of ocean ventilation

NASA Astrophysics Data System (ADS)

MacGilchrist, Graeme A.; Marshall, David P.; Johnson, Helen L.; Lique, Camille; Thomas, Matthew

2017-09-01

Ventilation of the upper ocean plays an important role in climate variability on interannual to decadal timescales by influencing the exchange of heat and carbon dioxide between the atmosphere and ocean. The turbulent nature of ocean circulation, manifest in a vigorous mesoscale eddy field, means that pathways of ventilation, once thought to be quasi-laminar, are in fact highly chaotic. We characterize the chaotic nature of ventilation pathways according to a nondimensional "filamentation number," which estimates the reduction in filament width of a ventilated fluid parcel due to mesoscale strain. In the subtropical North Atlantic of an eddy-permitting ocean model, the filamentation number is large everywhere across three upper ocean density surfaces—implying highly chaotic ventilation pathways—and increases with depth. By mapping surface ocean properties onto these density surfaces, we directly resolve the highly filamented structure and confirm that the filamentation number captures its spatial variability. These results have implications for the spreading of atmospherically-derived tracers into the ocean interior.

Design considerations of high-performance InGaAs/InP single-photon avalanche diodes for quantum key distribution.

PubMed

Ma, Jian; Bai, Bing; Wang, Liu-Jun; Tong, Cun-Zhu; Jin, Ge; Zhang, Jun; Pan, Jian-Wei

2016-09-20

InGaAs/InP single-photon avalanche diodes (SPADs) are widely used in practical applications requiring near-infrared photon counting such as quantum key distribution (QKD). Photon detection efficiency and dark count rate are the intrinsic parameters of InGaAs/InP SPADs, due to the fact that their performances cannot be improved using different quenching electronics given the same operation conditions. After modeling these parameters and developing a simulation platform for InGaAs/InP SPADs, we investigate the semiconductor structure design and optimization. The parameters of photon detection efficiency and dark count rate highly depend on the variables of absorption layer thickness, multiplication layer thickness, excess bias voltage, and temperature. By evaluating the decoy-state QKD performance, the variables for SPAD design and operation can be globally optimized. Such optimization from the perspective of specific applications can provide an effective approach to design high-performance InGaAs/InP SPADs.

Gorlin-Goltz syndrome: An often missed diagnosis.

PubMed

Thomas, Ninan; Vinod, Sankar V; George, Arun; Varghese, Aabu

2016-01-01

Gorlin-Goltz syndrome due to its high variability in expression are often not diagnosed as the syndrome and often managed same as that of odontogenic keratocyst. But a more careful approach for the syndrome is needed as there is high chance of malignant changes owing to improper management of the syndrome. In this manuscript a case report of Gorlin-Goltz syndrome with the diagnostic features of the same in Indian population along with the difference in treatment protocol from treating an odontogenic keratocyst is described with review of literature.

Gorlin–Goltz syndrome: An often missed diagnosis

PubMed Central

Thomas, Ninan; Vinod, Sankar V.; George, Arun; Varghese, Aabu

2016-01-01

Gorlin-Goltz syndrome due to its high variability in expression are often not diagnosed as the syndrome and often managed same as that of odontogenic keratocyst. But a more careful approach for the syndrome is needed as there is high chance of malignant changes owing to improper management of the syndrome. In this manuscript a case report of Gorlin-Goltz syndrome with the diagnostic features of the same in Indian population along with the difference in treatment protocol from treating an odontogenic keratocyst is described with review of literature PMID:27563620

Analysis and parameterization of absorption properties of northern Norwegian coastal water

NASA Astrophysics Data System (ADS)

Nima, Ciren; Frette, Øyvind; Hamre, Børge; Erga, Svein Rune; Chen, Yi-Chun; Zhao, Lu; Sørensen, Kai; Norli, Marit; Stamnes, Knut; Muyimbwa, Dennis; Ssenyonga, Taddeo; Ssebiyonga, Nicolausi; Stamnes, Jakob J.

2017-02-01

Coastal water bodies are generally classified as Case 2 water, in which non-algal particles (NAP) and colored dissolved organic matter (CDOM) contribute significantly to the optical properties in addition to phytoplankton. These three constituents vary independently in Case 2 water and tend to be highly variable in space and time. We present data from measurements and analyses of the spectral absorption due to CDOM, total suspended matter (TSM), phytoplankton, and NAP in high-latitude northern Norwegian coastal water based on samples taken in spring, summer, and autumn.

Variable Deflection Response of Sensitive CNT-on-Fiber Artificial Hair Sensors from CNT Synthesis in High Aspect Ratio Microcavities (Postprint)

DTIC Science & Technology

2015-04-01

sensors are suitable flow sensor candidates for insect to bird scale low-Reynolds-number flyers due to their low power consumption, light weight, high...elastic measurements and modeling,” Carbon, 66(0), 377-386 (2014). [14] M. R. Maschmann, G. J. Ehlert, S. J. Park et al., “Visualizing Strain Evolution ...Maschmann, and J. Baur, " Morphology control in hierarchical fibers for applications in hair flow sensors." [20] N. Yamamoto, A. John Hart, E. J

Flood Control Burlington Dam, Souris River, North Dakota. Final Environment Impact Statement.

DTIC Science & Technology

1978-01-01

runoft would also be held at 500 cfs.) After spring runoff , the Lake Darling pool would be lowered to elevation 1596.0 at which point the USFWS would...highly variable, with annual runoff at Minot ranging from a low of 940 acre-feet in 1931 and 1937 to a high of 801,000 acre-feet in 1976. Flows are usually...greatest In April and May due to runoff from snowmelt and 1;utlrai 6prlni ,i. Flowq are generally very low during fall and winter with periods of no

Connecting health-related quality of life and mental health in dementia caregivers from Colombia, South America.

PubMed

Perrin, Paul B; Morgan, Matthew; Aretouli, Eleni; Sutter, Megan; Snipes, Daniel J; Hoyos, Guillermo Ramirez; Buraye, Jacqueline Arabia; Arango-Lasprilla, Juan Carlos

2014-01-01

Research in Caucasian populations has begun to examine the broad associations between physical and mental health in dementia caregivers. However, the examination of this relationship in Latin America is largely absent from the literature despite the fact that the region will see a major increase in dementia cases over the next 20 years. The current study examined the associations between health-related quality of life (HRQOL) and mental health in 90 dementia caregivers from Colombia, South America. A canonical correlation found that higher caregiver HRQOL was related to better mental health, as expected. Caregivers with high vitality and low role limitations due to physical problems tended to have low depression and high satisfaction with life. Follow-up multiple regressions found that caregiver role limitations due to physical problems was uniquely associated with satisfaction with life, whereas vitality, role limitations due to physical problems, and pain were uniquely associated with burden (although the pain effect was likely error due to a suppressor effect). Additionally, vitality and social functioning were uniquely negatively related to depression. Because of the extremely high overlap between these two sets of variables, dementia interventions are needed in Latin America that target both caregiver mental and physical health, as both likely operate in unison and influence each other.

Characterization of N-nitrosodimethylamine formation from the ozonation of ranitidine.

PubMed

Lv, Juan; Wang, Lin; Li, Yongmei

2017-08-01

N-nitrosodimethylamine (NDMA) is an emerging disinfection by-product which is formed during water disinfection in the presence of amine-based precursors. Ranitidine, as one kind of amine-based pharmaceuticals, has been identified as NDMA precursor with high NDMA molar conversion during chloramination. This study focused on the characterization of NDMA formation during ozonation of ranitidine. Influences of operational variables (ozone dose, pH value) and water matrix on NDMA generation as well as ranitidine degradation were evaluated. The results indicate high reactivity of ranitidine with ozone. Dimethylamine (DMA) and NDMA were generated due to ranitidine oxidation. High pH value caused more NDMA accumulation. NDMA formation was inhibited under acid conditions (pH≤5) mainly due to the protonation of amines. Water matrix such as HCO 3 - and humic acid impacted NDMA generation due to OH scavenging. Compared with OH, ozone molecules dominated the productions of DMA and NDMA. However, OH was a critical factor in NDMA degradation. Transformation products of ranitidine during ozonation were identified using gas chromatography-mass spectrometry. Among these products, just DMA and N,N-dimethylformamide could contribute to NDMA formation due to the DMA group in the molecular structures. The NDMA formation pathway from ranitidine ozonation was also proposed. Copyright © 2017. Published by Elsevier B.V.

Hydrologic Remote Sensing and Land Surface Data Assimilation.

PubMed

Moradkhani, Hamid

2008-05-06

Accurate, reliable and skillful forecasting of key environmental variables such as soil moisture and snow are of paramount importance due to their strong influence on many water resources applications including flood control, agricultural production and effective water resources management which collectively control the behavior of the climate system. Soil moisture is a key state variable in land surface-atmosphere interactions affecting surface energy fluxes, runoff and the radiation balance. Snow processes also have a large influence on land-atmosphere energy exchanges due to snow high albedo, low thermal conductivity and considerable spatial and temporal variability resulting in the dramatic change on surface and ground temperature. Measurement of these two variables is possible through variety of methods using ground-based and remote sensing procedures. Remote sensing, however, holds great promise for soil moisture and snow measurements which have considerable spatial and temporal variability. Merging these measurements with hydrologic model outputs in a systematic and effective way results in an improvement of land surface model prediction. Data Assimilation provides a mechanism to combine these two sources of estimation. Much success has been attained in recent years in using data from passive microwave sensors and assimilating them into the models. This paper provides an overview of the remote sensing measurement techniques for soil moisture and snow data and describes the advances in data assimilation techniques through the ensemble filtering, mainly Ensemble Kalman filter (EnKF) and Particle filter (PF), for improving the model prediction and reducing the uncertainties involved in prediction process. It is believed that PF provides a complete representation of the probability distribution of state variables of interests (according to sequential Bayes law) and could be a strong alternative to EnKF which is subject to some limitations including the linear updating rule and assumption of jointly normal distribution of errors in state variables and observation.

An energy balance model exploration of the impacts of interactions between surface albedo, cloud cover and water vapor on polar amplification

NASA Astrophysics Data System (ADS)

Södergren, A. Helena; McDonald, Adrian J.; Bodeker, Gregory E.

2017-11-01

We examine the effects of non-linear interactions between surface albedo, water vapor and cloud cover (referred to as climate variables) on amplified warming of the polar regions, using a new energy balance model. Our simulations show that the sum of the contributions to surface temperature changes due to any variable considered in isolation is smaller than the temperature changes from coupled feedback simulations. This non-linearity is strongest when all three climate variables are allowed to interact. Surface albedo appears to be the strongest driver of this non-linear behavior, followed by water vapor and clouds. This is because increases in longwave radiation absorbed by the surface, related to increases in water vapor and clouds, and increases in surface absorbed shortwave radiation caused by a decrease in surface albedo, amplify each other. Furthermore, our results corroborate previous findings that while increases in cloud cover and water vapor, along with the greenhouse effect itself, warm the polar regions, water vapor also significantly warms equatorial regions, which reduces polar amplification. Changes in surface albedo drive large changes in absorption of incoming shortwave radiation, thereby enhancing surface warming. Unlike high latitudes, surface albedo change at low latitudes are more constrained. Interactions between surface albedo, water vapor and clouds drive larger increases in temperatures in the polar regions compared to low latitudes. This is in spite of the fact that, due to a forcing, cloud cover increases at high latitudes and decreases in low latitudes, and that water vapor significantly enhances warming at low latitudes.

Joint Adaptive Mean-Variance Regularization and Variance Stabilization of High Dimensional Data.

PubMed

Dazard, Jean-Eudes; Rao, J Sunil

2012-07-01

The paper addresses a common problem in the analysis of high-dimensional high-throughput "omics" data, which is parameter estimation across multiple variables in a set of data where the number of variables is much larger than the sample size. Among the problems posed by this type of data are that variable-specific estimators of variances are not reliable and variable-wise tests statistics have low power, both due to a lack of degrees of freedom. In addition, it has been observed in this type of data that the variance increases as a function of the mean. We introduce a non-parametric adaptive regularization procedure that is innovative in that : (i) it employs a novel "similarity statistic"-based clustering technique to generate local-pooled or regularized shrinkage estimators of population parameters, (ii) the regularization is done jointly on population moments, benefiting from C. Stein's result on inadmissibility, which implies that usual sample variance estimator is improved by a shrinkage estimator using information contained in the sample mean. From these joint regularized shrinkage estimators, we derived regularized t-like statistics and show in simulation studies that they offer more statistical power in hypothesis testing than their standard sample counterparts, or regular common value-shrinkage estimators, or when the information contained in the sample mean is simply ignored. Finally, we show that these estimators feature interesting properties of variance stabilization and normalization that can be used for preprocessing high-dimensional multivariate data. The method is available as an R package, called 'MVR' ('Mean-Variance Regularization'), downloadable from the CRAN website.

Joint Adaptive Mean-Variance Regularization and Variance Stabilization of High Dimensional Data

PubMed Central

Dazard, Jean-Eudes; Rao, J. Sunil

2012-01-01

The paper addresses a common problem in the analysis of high-dimensional high-throughput “omics” data, which is parameter estimation across multiple variables in a set of data where the number of variables is much larger than the sample size. Among the problems posed by this type of data are that variable-specific estimators of variances are not reliable and variable-wise tests statistics have low power, both due to a lack of degrees of freedom. In addition, it has been observed in this type of data that the variance increases as a function of the mean. We introduce a non-parametric adaptive regularization procedure that is innovative in that : (i) it employs a novel “similarity statistic”-based clustering technique to generate local-pooled or regularized shrinkage estimators of population parameters, (ii) the regularization is done jointly on population moments, benefiting from C. Stein's result on inadmissibility, which implies that usual sample variance estimator is improved by a shrinkage estimator using information contained in the sample mean. From these joint regularized shrinkage estimators, we derived regularized t-like statistics and show in simulation studies that they offer more statistical power in hypothesis testing than their standard sample counterparts, or regular common value-shrinkage estimators, or when the information contained in the sample mean is simply ignored. Finally, we show that these estimators feature interesting properties of variance stabilization and normalization that can be used for preprocessing high-dimensional multivariate data. The method is available as an R package, called ‘MVR’ (‘Mean-Variance Regularization’), downloadable from the CRAN website. PMID:22711950

The Importance of Freshwater to Spatial Variability of Aragonite Saturation State in the Gulf of Alaska

NASA Astrophysics Data System (ADS)

Siedlecki, Samantha A.; Pilcher, Darren J.; Hermann, Albert J.; Coyle, Ken; Mathis, Jeremy

2017-11-01

High-latitude and subpolar regions like the Gulf of Alaska (GOA) are more vulnerable than equatorial regions to rising carbon dioxide (CO2) levels, in part due to local processes that amplify the global signal. Recent field observations have shown that the shelf of the GOA is currently experiencing seasonal corrosive events (carbonate mineral saturation states Ω, Ω < 1), including suppressed Ω in response to ocean acidification as well as local processes like increased low-alkalinity glacial meltwater discharge. While the glacial discharge mainly influences the inner shelf, on the outer shelf, upwelling brings corrosive waters from the deep GOA. In this work, we develop a high-resolution model for carbon dynamics in the GOA, identify regions of high variability of Ω, and test the sensitivity of those regions to changes in the chemistry of glacial meltwater discharge. Results indicate the importance of this climatically sensitive and relatively unconstrained regional freshwater forcing for Ω variability in the nearshore. The increase was nearly linear at 0.002 Ω per 100 µmol/kg increase in alkalinity in the freshwater runoff. We find that the local winds, biological processes, and freshwater forcing all contribute to the spatial distribution of Ω and identify which of these three is highly correlated to the variability in Ω. Given that the timing and magnitude of these processes will likely change during the next few decades, it is critical to elucidate the effect of local processes on the background ocean acidification signal using robust models, such as the one described here.

Simulations of the Boreal Winter Upper Mesosphere and Lower Thermosphere With Meteorological Specifications in SD-WACCM-X

NASA Astrophysics Data System (ADS)

Sassi, Fabrizio; Siskind, David E.; Tate, Jennifer L.; Liu, Han-Li; Randall, Cora E.

2018-04-01

We investigate the benefit of high-altitude nudging in simulations of the structure and short-term variability of the upper mesosphere and lower thermosphere (UMLT) dynamical meteorology during boreal winter, specifically around the time of the January 2009 sudden stratospheric warming. We compare simulations using the Specified Dynamics, Whole Atmosphere Community Climate Model, extended version, nudged using atmospheric specifications generated by the Navy Operational Global Atmospheric Prediction System, Advanced Level Physics High Altitude. Two sets of simulations are carried out: one uses nudging over a vertical domain from 0 to 90 km; the other uses nudging over a vertical domain from 0 to 50 km. The dynamical behavior is diagnosed from ensemble mean and standard deviation of winds, temperature, and zonal accelerations due to resolved and parameterized waves. We show that the dynamical behavior of the UMLT is quite different in the two experiments, with prominent differences in the structure and variability of constituent transport. We compare the results of our numerical experiments to observations of carbon monoxide by the Atmospheric Chemistry Experiment-Fourier Transform Spectrometer to show that the high-altitude nudging is capable of reproducing with high fidelity the observed variability, and traveling planetary waves are a crucial component of the dynamics. The results of this study indicate that to capture the key physical processes that affect short-term variability (defined as the atmospheric behavior within about 10 days of a stratospheric warming) in the UMLT, specification of the atmospheric state in the stratosphere alone is not sufficient, and upper atmospheric specifications are needed.

Consistency of kinematic and kinetic patterns during a prolonged spell of cricket fast bowling: an exploratory laboratory study.

PubMed

Schaefer, Andrew; O'dwyer, Nicholas; Ferdinands, René E D; Edwards, Suzi

2018-03-01

Due to the high incidence of lumbar spine injury in fast bowlers, international cricket organisations advocate limits on workload for bowlers under 19 years of age in training/matches. The purpose of this study was to determine whether significant changes in either fast bowling technique or movement variability could be detected throughout a 10-over bowling spell that exceeded the recommended limit. Twenty-five junior male fast bowlers bowled at competition pace while three-dimensional kinematic and kinetic data were collected for the leading leg, trunk and bowling arm. Separate analyses for the mean and within-participant standard deviation of each variable were performed using repeated measures factorial analyses of variance and computation of effect sizes. No substantial changes were observed in mean values or variability of any kinematic, kinetic or performance variables, which instead revealed a high degree of consistency in kinematic and kinetic patterns. Therefore, the suggestion that exceeding the workload limit per spell causes technique- and loading-related changes associated with lumbar injury risk is not valid and cannot be used to justify the restriction of bowling workload. For injury prevention, the focus instead should be on the long-term effect of repeated spells and on the fast bowling technique itself.

Comparative assessment of lowland and highland Smallholder farmers' vulnerability to climate variability in Ethiopia

NASA Astrophysics Data System (ADS)

Ayal, D. Y., Sr.; Abshare, M. W. M.; Desta, S. D.; Filho, W. L.

2015-12-01

Desalegn Yayeh Ayal P.O.BOX 150129 Addis Ababa University Ethiopia Mobil +251910824784 Abstract Smallholder farmers' near term scenario (2010-2039) vulnerability nature and magnitude was examined using twenty-two exposure, sensitivity and adaptive capacity vulnerability indicators. Assessment of smallholder farmers' vulnerability to climate variability revealed the importance of comprehending exposure, sensitivity and adaptive capacity induces. Due to differences in level of change in rainfall, temperature, drought frequency, their environmental interaction and variations on adaptive capacity the nature and magnitude of smallholder farmers vulnerability to physical, biological and epidemiological challenges of crop and livestock production varied within and across agro-ecologies. Highlanders' sensitive relates with high population density, erosion and crop disease and pest damage occurrence. Whereas lowlanders will be more sensitive to high crop disease and pest damage, provenance of livestock disease, absence of alternative water sources, less diversified agricultural practices. However, with little variations in the magnitude and nature of vulnerability, both highlanders and lowlanders are victims of climate variability and change. Given the ever increasing population, temperature and unpredictable nature of rainfall variability, the study concluded that future adaptation strategies should capitalize on preparing smallholder farmers for both extremes- excess rainfall and flooding on the one hand and severe drought on the other.

Temporally variable environments maintain more beta-diversity in Mediterranean landscapes

NASA Astrophysics Data System (ADS)

Martin, Beatriz; Ferrer, Miguel

2015-10-01

We examined the relationships between different environmental factors and the alpha and beta-diversity of terrestrial vertebrates (birds, mammals, amphibians and reptiles) in a Mediterranean region at the landscape level. We investigated whether the mechanisms underlying alpha and beta-diversity patterns are influenced by energy availability, habitat heterogeneity and temporal variability and if the drivers of the diversity patterns differed between both components of diversity. We defined alpha-diversity as synonym of species richness whereas beta-diversity was measured as distinctiveness. We evaluated a total of 13 different predictors using generalized linear mixed model (GLMM) analysis. Habitat spatial heterogeneity increased alpha-diversity, but contrastingly, it did not significantly affect beta-diversity among sites. Disturbed landscapes may show higher habitat spatial variation and higher alpha-diversity due to the contribution of highly generalist species that are wide-distributed and do not differ in composition (beta-diversity) among different sites within the region. Contrastingly, higher beta-diversity levels were negatively related to more stable sites in terms of temporal environmental variation. This negative relationship between environmental stability and beta-diversity levels is explained in terms of species adaptation to the local environmental conditions. Our study highlights the importance of temporal environmental variability in maintaining beta-diversity patterns under highly variable environmental conditions.

RAPID OPTICAL VARIABILITY IN BLAZAR S5 0716+71 DURING 2010 MARCH

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chandra, S.; Baliyan, K. S.; Ganesh, S.

We report rapid optical variability for the blazar S5 0716+71 during 2010 March 8-10 and 19-20 in the CCD observations made from Mt. Abu Infrared Observatory. The light curves are constructed for a duration longer than 3 hr each night, with very high temporal resolution ({approx}45 s in the R band). During 2010 March 8, the source smoothly decayed by about 0.15 mag in 2.88 hr, apart from a fast flicker lasting about 30 minutes. S5 0716+71 brightened during March 9 and 10, showing high activity, while it was relatively faint (>14 mag in the R band) albeit variable duringmore » March 19-20. During March 9 and 10, rapid flickers in the intensity modulated the long-term intra-night ({approx}3 hr) variations. The present observations suggest that the blazar S5 0716+71 showed night-to-night and intra-night variability at various timescales with a 100% duty cycle for variation along with microvariability at significant levels. On a night-to-night basis, the source exhibits mild bluer-when-brighter nature. The interaction of shocks with local inhomogeneities in the jet appears to cause intra-night variations, while microvariations could be due to small-scale perturbations intrinsic to the jet.« less

A comparison of the sensitivity, specificity, and molecular weight accuracy of three different commercially available Hyaluronan ELISA-like assays.

PubMed

Haserodt, Sarah; Aytekin, Metin; Dweik, Raed A

2011-02-01

Hyaluronan (HA) is a glycosaminoglycan found in the extracellular matrix and ranges from several thousand to millions of daltons in size. HA has importance in various pathological conditions and is known to be elevated in several diseases. Three commonly used, commercially available HA enzyme-linked immunosorbent assay (ELISA)-like assays (from Corgenix, Echelon and R&D) were compared on the basis of accuracy, sample variability and ability to measure a range of HA sizes. The Corgenix HA ELISA-like assay displayed the lowest intra-assay variability [coefficient of variation (CV) = 11.7 ± 3.6%], followed by R&D (CV = 12.3 ± 4.6%) and Echelon (CV = 18.9 ± 9.2%). Interassay variability was also lowest for the Corgenix assay (CV = 6.0%), intermediate for the Echelon assay (9.5%) and highest for the R&D assay (CV = 34.1%). The high interassay variability seen for the R&D assay may have been due to the effect of dilution, since the dilution-independent interassay variability was 15.5%. The concentration of the standard HA was overestimated by the Echelon assay by 85% and underestimated by the R&D and Corgenix assays by 34 and 32%, respectively. The Echelon HA ELISA-like assay was the most effective at measuring all sizes of HA tested (2 MDa and 132, 66 and 6.4 kDa), whereas the Corgenix and R&D assays were unable to detect 6.4 kDa HA. These findings suggest that the Echelon HA ELISA-like assay is better suited for size-sensitive HA measurements but has a relatively high variability. The Corgenix and R&D HA ELISA-like assays have low variability and high accuracy but are not suitable for detecting low-molecular-weight HA.

Temperature dependent simulation of diamond depleted Schottky PIN diodes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hathwar, Raghuraj; Dutta, Maitreya; Chowdhury, Srabanti

2016-06-14

Diamond is considered as an ideal material for high field and high power devices due to its high breakdown field, high lightly doped carrier mobility, and high thermal conductivity. The modeling and simulation of diamond devices are therefore important to predict the performances of diamond based devices. In this context, we use Silvaco{sup ®} Atlas, a drift-diffusion based commercial software, to model diamond based power devices. The models used in Atlas were modified to account for both variable range and nearest neighbor hopping transport in the impurity bands associated with high activation energies for boron doped and phosphorus doped diamond.more » The models were fit to experimentally reported resistivity data over a wide range of doping concentrations and temperatures. We compare to recent data on depleted diamond Schottky PIN diodes demonstrating low turn-on voltages and high reverse breakdown voltages, which could be useful for high power rectifying applications due to the low turn-on voltage enabling high forward current densities. Three dimensional simulations of the depleted Schottky PIN diamond devices were performed and the results are verified with experimental data at different operating temperatures.« less

Variable speed induction motor operation from a 20-kHz power bus

NASA Technical Reports Server (NTRS)

Hansen, Irving G.

1989-01-01

Induction motors are recognized for their simple rugged construction. To date, however, their application to variable speed or servo drives was hampered by limitations on their control. Induction motor drives tend to be complex and to display troublesome low speed characteristics due in part to nonsinusoidal driving voltages. A technique was developed which involves direct synthesis of sinusoidal driving voltages from a high frequency power bus and independent control of frequency and voltages. Separation of frequency and voltage allows independent control of rotor and stator flux, full four quadrant operation, and instantaneous torque control. Recent test results, current status of the technology, and proposed aerospace applications will be discussed.

Variable speed induction motor operation from a 20-kHz power bus

NASA Technical Reports Server (NTRS)

Hansen, Irving G.

1989-01-01

Induction motors are recognized for their simple rugged construction to date, however, their application to variable speed or servo drives has been hampered by limitations on their control. Induction motor drives tend to be complex and to display troublesome low speed characteristics due in part to nonsinusoidal driving voltages. A technique was developed which involves direct synthesis of sinusoidal driving voltages from a high frequency power bus and independent control of frequency and voltages. Separation offrequency and voltage allows independent control of rotor and stator flux, full four-quadrant operation, and instantaneous torque control. Recent test results, current status of the technology, and proposed aerospace applications will be discussed.

Localized scleroderma: clinical spectrum and therapeutic update*

PubMed Central

Careta, Mariana Figueiroa; Romiti, Ricardo

2015-01-01

Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement, and localized scleroderma or morphea which classically presents benign and self-limited evolution and is confined to the skin and/or underlying tissues. Localized scleroderma is a rare disease of unknown etiology. Recent studies show that the localized form may affect internal organs and have variable morbidity. Treatment should be started very early, before complications occur due to the high morbidity of localized scleroderma. In this review, we report the most important aspects and particularities in the treatment of patients diagnosed with localized scleroderma. PMID:25672301

Localized scleroderma: clinical spectrum and therapeutic update.

PubMed

Careta, Mariana Figueiroa; Romiti, Ricardo

2015-01-01

Scleroderma is a rare connective tissue disease that is manifested by cutaneous sclerosis and variable systemic involvement. Two categories of scleroderma are known: systemic sclerosis, characterized by cutaneous sclerosis and visceral involvement, and localized scleroderma or morphea which classically presents benign and self-limited evolution and is confined to the skin and/or underlying tissues. Localized scleroderma is a rare disease of unknown etiology. Recent studies show that the localized form may affect internal organs and have variable morbidity. Treatment should be started very early, before complications occur due to the high morbidity of localized scleroderma. In this review, we report the most important aspects and particularities in the treatment of patients diagnosed with localized scleroderma.

Continuous-variable quantum key distribution with 1 Mbps secure key rate.

PubMed

Huang, Duan; Lin, Dakai; Wang, Chao; Liu, Weiqi; Fang, Shuanghong; Peng, Jinye; Huang, Peng; Zeng, Guihua

2015-06-29

We report the first continuous-variable quantum key distribution (CVQKD) experiment to enable the creation of 1 Mbps secure key rate over 25 km standard telecom fiber in a coarse wavelength division multiplexers (CWDM) environment. The result is achieved with two major technological advances: the use of a 1 GHz shot-noise-limited homodyne detector and the implementation of a 50 MHz clock system. The excess noise due to noise photons from local oscillator and classical data channels in CWDM is controlled effectively. We note that the experimental verification of high-bit-rate CVQKD in the multiplexing environment is a significant step closer toward large-scale deployment in fiber networks.

Carbon Dioxide Physiological Forcing Dominates Projected Eastern Amazonian Drying

NASA Astrophysics Data System (ADS)

Richardson, T. B.; Forster, P. M.; Andrews, T.; Boucher, O.; Faluvegi, G.; Fläschner, D.; Kasoar, M.; Kirkevâg, A.; Lamarque, J.-F.; Myhre, G.; Olivié, D.; Samset, B. H.; Shawki, D.; Shindell, D.; Takemura, T.; Voulgarakis, A.

2018-03-01

Future projections of east Amazonian precipitation indicate drying, but they are uncertain and poorly understood. In this study we analyze the Amazonian precipitation response to individual atmospheric forcings using a number of global climate models. Black carbon is found to drive reduced precipitation over the Amazon due to temperature-driven circulation changes, but the magnitude is uncertain. CO2 drives reductions in precipitation concentrated in the east, mainly due to a robustly negative, but highly variable in magnitude, fast response. We find that the physiological effect of CO2 on plant stomata is the dominant driver of the fast response due to reduced latent heating and also contributes to the large model spread. Using a simple model, we show that CO2 physiological effects dominate future multimodel mean precipitation projections over the Amazon. However, in individual models temperature-driven changes can be large, but due to little agreement, they largely cancel out in the model mean.

Influence of elevated temperature and acid mine drainage on mortality of the crayfish Cambarus bartonii

USGS Publications Warehouse

Hartman, K.J.; Hom, C.D.; Mazik, P.M.

2010-01-01

Effects of elevated temperature and acid mine drainage (AMD) on crayfish mortality were investigated in the Stony River, Grant County, West Virginia. During summers 2003 and 2004, four-week in situ bioassays were performed along a thermal and AMD gradient with the native crayfish Cambarus bartonii. Crayfish mortality was analyzed in conjunction with temperature and AMD related variables (pH, specific conductivity). Mortality was significantly higher (48-88%) at sites with high temperatures during 2003 (max = 33.0??C), but no significant differences were observed in 2004 (max = 32.0??C). Temperatures were higher in 2003 than 2004 due to increased discharge from a cooling reservoir flowing into the river. Additionally, duration of high temperature was approximately four days in 2003 as compared with only one day in 2004. No significant relationship between acid mine drainage variables and crayfish mortality was apparent.

VLSI implementation of a new LMS-based algorithm for noise removal in ECG signal

NASA Astrophysics Data System (ADS)

Satheeskumaran, S.; Sabrigiriraj, M.

2016-06-01

Least mean square (LMS)-based adaptive filters are widely deployed for removing artefacts in electrocardiogram (ECG) due to less number of computations. But they posses high mean square error (MSE) under noisy environment. The transform domain variable step-size LMS algorithm reduces the MSE at the cost of computational complexity. In this paper, a variable step-size delayed LMS adaptive filter is used to remove the artefacts from the ECG signal for improved feature extraction. The dedicated digital Signal processors provide fast processing, but they are not flexible. By using field programmable gate arrays, the pipelined architectures can be used to enhance the system performance. The pipelined architecture can enhance the operation efficiency of the adaptive filter and save the power consumption. This technique provides high signal-to-noise ratio and low MSE with reduced computational complexity; hence, it is a useful method for monitoring patients with heart-related problem.

Soundscapes from a Tropical Eastern Pacific reef and a Caribbean Sea reef

NASA Astrophysics Data System (ADS)

Staaterman, E.; Rice, A. N.; Mann, D. A.; Paris, C. B.

2013-06-01

Underwater soundscapes vary due to the abiotic and biological components of the habitat. We quantitatively characterized the acoustic environments of two coral reef habitats, one in the Tropical Eastern Pacific (Panama) and one in the Caribbean (Florida Keys), over 2-day recording durations in July 2011. We examined the frequency distribution, temporal variability, and biological patterns of sound production and found clear differences. The Pacific reef exhibited clear biological patterns and high temporal variability, such as the onset of snapping shrimp noise at night, as well as a 400-Hz daytime band likely produced by damselfish. In contrast, the Caribbean reef had high sound levels in the lowest frequencies, but lacked clear temporal patterns. We suggest that acoustic measures are an important element to include in reef monitoring programs, as the acoustic environment plays an important role in the ecology of reef organisms at multiple life-history stages.

High-order sliding-mode control for blood glucose regulation in the presence of uncertain dynamics.

PubMed

Hernández, Ana Gabriela Gallardo; Fridman, Leonid; Leder, Ron; Andrade, Sergio Islas; Monsalve, Cristina Revilla; Shtessel, Yuri; Levant, Arie

2011-01-01

The success of blood glucose automatic regulation depends on the robustness of the control algorithm used. It is a difficult task to perform due to the complexity of the glucose-insulin regulation system. The variety of model existing reflects the great amount of phenomena involved in the process, and the inter-patient variability of the parameters represent another challenge. In this research a High-Order Sliding-Mode Control is proposed. It is applied to two well known models, Bergman Minimal Model, and Sorensen Model, to test its robustness with respect to uncertain dynamics, and patients' parameter variability. The controller designed based on the simulations is tested with the specific Bergman Minimal Model of a diabetic patient whose parameters were identified from an in vivo assay. To minimize the insulin infusion rate, and avoid the hypoglycemia risk, the glucose target is a dynamical profile.

Motor skills under varied gravitoinertial force in parabolic flight

NASA Astrophysics Data System (ADS)

Ross, Helen E.

Parabolic flight produces brief alternating periods of high and low gravitoinertial force. Subjects were tested on various paper-and-pencil aiming and tapping tasks during both normal and varied gravity in flight. It was found that changes in g level caused directional errors in the z body axis (the gravity axis), the arm aiming too high under 0g and too low under 2g. The standard deviation also increased for both vertical and lateral movements in the mid-frontal plane. Both variable and directional errors were greater under 0g than 2g. In an unpaced reciprocal tapping task subjects tended to increase their error rate rather than their movement time, but showed a non-significant trend towards slower speeds under 0g for all movement orientations. Larger variable errors or slower speeds were probably due to the difficulty of re-organising a motor skill in an unfamiliar force environment, combined with anchorage difficulties under 0g.

On quasi-periodic variations of low-energy cosmic rays observed near earth.

PubMed

Kudela, Karel; Langer, Ronald

2015-06-01

Cosmic ray (CR) may partially, especially at high altitudes, contribute to the dosimetric characteristics. Along with irregular CR variations as Forbush decreases and solar particle events are, the quasi-periodic variations may be of some relevance too. A very short review (with references to original papers) of the present knowledge of various types of such variations is presented, namely (i) diurnal wave, (ii) ~27 d variability due to the solar rotation, (iii) Rieger-type periodicity, and (iv) quasi-biennial oscillations as well as waves on longer time scales related to solar activity and to polarity of magnetic field of the Sun. Variability is illustrated in measurements of secondary CR on the ground including the high-altitude observations at Lomnický štít. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Climate-Driven Crop Yield and Yield Variability and Climate Change Impacts on the U.S. Great Plains Agricultural Production.

PubMed

Kukal, Meetpal S; Irmak, Suat

2018-02-22

Climate variability and trends affect global crop yields and are characterized as highly dependent on location, crop type, and irrigation. U.S. Great Plains, due to its significance in national food production, evident climate variability, and extensive irrigation is an ideal region of investigation for climate impacts on food production. This paper evaluates climate impacts on maize, sorghum, and soybean yields and effect of irrigation for individual counties in this region by employing extensive crop yield and climate datasets from 1968-2013. Variability in crop yields was a quarter of the regional average yields, with a quarter of this variability explained by climate variability, and temperature and precipitation explained these in singularity or combination at different locations. Observed temperature trend was beneficial for maize yields, but detrimental for sorghum and soybean yields, whereas observed precipitation trend was beneficial for all three crops. Irrigated yields demonstrated increased robustness and an effective mitigation strategy against climate impacts than their non-irrigated counterparts by a considerable fraction. The information, data, and maps provided can serve as an assessment guide for planners, managers, and policy- and decision makers to prioritize agricultural resilience efforts and resource allocation or re-allocation in the regions that exhibit risk from climate variability.

Consequences of an uncertain mass mortality regime triggered by climate variability on giant clam population management in the Pacific Ocean.

PubMed

Van Wynsberge, Simon; Andréfouët, Serge; Gaertner-Mazouni, Nabila; Remoissenet, Georges

2018-02-01

Despite actions to manage sustainably tropical Pacific Ocean reef fisheries, managers have faced failures and frustrations because of unpredicted mass mortality events triggered by climate variability. The consequences of these events on the long-term population dynamics of living resources need to be better understood for better management decisions. Here, we use a giant clam (Tridacna maxima) spatially explicit population model to compare the efficiency of several management strategies under various scenarios of natural mortality, including mass mortality due to climatic anomalies. The model was parameterized by in situ estimations of growth and mortality and fishing effort, and was validated by historical and new in situ surveys of giant clam stocks in two French Polynesia lagoons. Projections on the long run (100 years) suggested that the best management strategy was a decrease of fishing pressure through quota implementation, regardless of the mortality regime considered. In contrast, increasing the minimum legal size of catch and closing areas to fishing were less efficient. When high mortality occurred due to climate variability, the efficiency of all management scenarios decreased markedly. Simulating El Niño Southern Oscillation event by adding temporal autocorrelation in natural mortality rates increased the natural variability of stocks, and also decreased the efficiency of management. These results highlight the difficulties that managers in small Pacific islands can expect in the future in the face of global warming, climate anomalies and new mass mortalities. Copyright © 2017 Elsevier Inc. All rights reserved.

Comparison of split double and triple twists in pair figure skating.

PubMed

King, Deborah L; Smith, Sarah L; Brown, Michele R; McCrory, Jean L; Munkasy, Barry A; Scheirman, Gary I

2008-05-01

In this study, we compared the kinematic variables of the split triple twist with those of the split double twist to help coaches and scientists understand these landmark pair skating skills. High-speed video was taken during the pair short and free programmes at the 2002 Salt Lake City Winter Olympics and the 2003 International Skating Union Grand Prix Finals. Three-dimensional analyses of 14 split double twists and 15 split triple twists from eleven pairs were completed. In spite of considerable variability in the performance variables among the pairs, the main difference between the split double twists and split triple twists was an increase in rotational rate. While eight of the eleven pairs relied primarily on an increased rotational rate to complete the split triple twist, three pairs employed a combined strategy of increased rotational rate and increased flight time due predominantly to delayed or lower catches. These results were similar to observations of jumps in singles skating for which the extra rotation is typically due to an increase in rotational velocity; increases in flight time come primarily from delayed landings as opposed to additional height during flight. Combining an increase in flight time and rotational rate may be a good strategy for completing the split triple twist in pair skating.

Scavenging rate ecoassay: a potential indicator of estuary condition.

PubMed

Porter, Augustine G; Scanes, Peter R

2015-01-01

Monitoring of estuary condition is essential due to the highly productive and often intensely impacted nature of these ecosystems. Assessment of the physico-chemical condition of estuaries is expensive and difficult due to naturally fluctuating water quality and biota. Assessing the vigour of ecosystem processes is an alternative method with potential to overcome much of the variability associated with physico-chemical measures. Indicators of estuary condition should have small spatial and temporal variability, have a predictable response to perturbation and be ecologically relevant. Here, we present tests of the first criterion, the spatio-temporal variability of a potential ecoassay measuring the rate of scavenging in estuaries. We hypothesised that the proposed scavenging ecoassay would not vary significantly among A) sites in an estuary, B) trips separated by weeks, or C) days in a trip. Because not all habitats are present in all estuaries, this test was undertaken in two habitats. When conducted over bare substrate there were occasional significant differences, but no discernible patterns, within levels of the experiment. When conducted over vegetated substrate, days within a trip did not vary significantly, but later trips experienced greater scavenging. This scavenging ecoassay shows potential as a tool for assessing the condition of estuarine ecosystems, and further exploration of this protocol is warranted by implementation in estuaries across a gradient of anthropogenic stress.

Do one percent of the forest fires cause ninety-nine percent of the damage? Forest Science

Treesearch

David Strauss; Larry Bednar; Romain Mees

1989-01-01

A relatively small number of forest fires are responsible for a very high proportion of the total damage. The proportion due to the fraction p of largest fires, when plotted against p, is a measure of variability of fire sizes that is especially sensitive to the important extreme events. We find the theoretical form of the plot for several commonly used distributions...

Diabetes insipidus, diabetes mellitus, optic atrophy, and deafness. 3 cases of 'DIDMOAD' syndrome.

PubMed Central

Richardson, J E; Hamilton, W

1977-01-01

Three children with diabetes insipidus, diabetes mellitus, optic atrophy, and high-tone deafness were shown to lack vasopressin, indicative of degeneration of the cells of the hypothalamic supraoptic nuclei. The syndrome being due to a single gene defect, inherited as an autosomal recessive, is therefore likely to be the result of an inborn error of metabolism with variable periods of latency in those affected. PMID:931428

Leisure Time of Young Due to Some Socio-Demographic Characteristics

ERIC Educational Resources Information Center

Ðuranovic, Marina; Opic, Siniša

2014-01-01

The aim of this paper is to explore the prevalence of activities in leisure time of the young. A survey was conducted on 1062 students in 8 primary (n=505; 47,6%) and high schools (n=557; 52,4%) in Sisak - Moslavina County in the Republic of Croatia. The questionnaire of spending leisure time used was made up of 30 variables on a five-degree scale…

Predicting Disease Progression in Scleroderma with Skin and Blood Biomarkers

DTIC Science & Technology

2015-10-01

AWARD NUMBER: W81XWH-13-1-0452 TITLE: Predicting Disease Progression in Scleroderma with Skin and Blood Biomarkers PRINCIPAL INVESTIGATOR: Dr...Predicting Disease Progression in Scleroderma with Skin and Blood 5a. CONTRACT NUMBER Biomarkers 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR...autoimmune disease associated with high morbidity and mortality primarily due to lung disease . There is a large variability in individual patients’ courses

Humidity and Gravimetric Equivalency Adjustments for Nephelometer-Based Particulate Matter Measurements of Emissions from Solid Biomass Fuel Use in Cookstoves

PubMed Central

Soneja, Sutyajeet; Chen, Chen; Tielsch, James M.; Katz, Joanne; Zeger, Scott L.; Checkley, William; Curriero, Frank C.; Breysse, Patrick N.

2014-01-01

Great uncertainty exists around indoor biomass burning exposure-disease relationships due to lack of detailed exposure data in large health outcome studies. Passive nephelometers can be used to estimate high particulate matter (PM) concentrations during cooking in low resource environments. Since passive nephelometers do not have a collection filter they are not subject to sampler overload. Nephelometric concentration readings can be biased due to particle growth in high humid environments and differences in compositional and size dependent aerosol characteristics. This paper explores relative humidity (RH) and gravimetric equivalency adjustment approaches to be used for the pDR-1000 used to assess indoor PM concentrations for a cookstove intervention trial in Nepal. Three approaches to humidity adjustment performed equivalently (similar root mean squared error). For gravimetric conversion, the new linear regression equation with log-transformed variables performed better than the traditional linear equation. In addition, gravimetric conversion equations utilizing a spline or quadratic term were examined. We propose a humidity adjustment equation encompassing the entire RH range instead of adjusting for RH above an arbitrary 60% threshold. Furthermore, we propose new integrated RH and gravimetric conversion methods because they have one response variable (gravimetric PM2.5 concentration), do not contain an RH threshold, and is straightforward. PMID:24950062

Humidity and gravimetric equivalency adjustments for nephelometer-based particulate matter measurements of emissions from solid biomass fuel use in cookstoves.

PubMed

Soneja, Sutyajeet; Chen, Chen; Tielsch, James M; Katz, Joanne; Zeger, Scott L; Checkley, William; Curriero, Frank C; Breysse, Patrick N

2014-06-19

Great uncertainty exists around indoor biomass burning exposure-disease relationships due to lack of detailed exposure data in large health outcome studies. Passive nephelometers can be used to estimate high particulate matter (PM) concentrations during cooking in low resource environments. Since passive nephelometers do not have a collection filter they are not subject to sampler overload. Nephelometric concentration readings can be biased due to particle growth in high humid environments and differences in compositional and size dependent aerosol characteristics. This paper explores relative humidity (RH) and gravimetric equivalency adjustment approaches to be used for the pDR-1000 used to assess indoor PM concentrations for a cookstove intervention trial in Nepal. Three approaches to humidity adjustment performed equivalently (similar root mean squared error). For gravimetric conversion, the new linear regression equation with log-transformed variables performed better than the traditional linear equation. In addition, gravimetric conversion equations utilizing a spline or quadratic term were examined. We propose a humidity adjustment equation encompassing the entire RH range instead of adjusting for RH above an arbitrary 60% threshold. Furthermore, we propose new integrated RH and gravimetric conversion methods because they have one response variable (gravimetric PM2.5 concentration), do not contain an RH threshold, and is straightforward.

Evidence of Dynamic Crustal Deformation in Tohoku, Japan, From Time-Varying Receiver Functions

NASA Astrophysics Data System (ADS)

Porritt, R. W.; Yoshioka, S.

2017-10-01

Temporal variation of crustal structure is key to our understanding of Earth processes on human timescales. Often, we expect that the most significant structural variations are caused by strong ground shaking associated with large earthquakes, and recent studies seem to confirm this. Here we test the possibility of using P receiver functions (PRF) to isolate structural variations over time. Synthetic receiver function tests indicate that structural variation could produce PRF changes on the same order of magnitude as random noise or contamination by local earthquakes. Nonetheless, we find significant variability in observed receiver functions over time at several stations located in northeastern Honshu. Immediately following the Tohoku-oki earthquake, we observe high PRF variation clustering spatially, especially in two regions near the beginning and end of the rupture plane. Due to the depth sensitivity of PRF and the timescales over which this variability is observed, we infer this effect is primarily due to fluid migration in volcanic regions and shear stress/strength reorganization. While the noise levels in PRF are high for this type of analysis, by sampling small data sets, the computational cost is lower than other methods, such as ambient noise, thereby making PRF a useful tool for estimating temporal variations in crustal structure.

An Intelligent Monitoring Network for Detection of Cracks in Anvils of High-Press Apparatus.

PubMed

Tian, Hao; Yan, Zhaoli; Yang, Jun

2018-04-09

Due to the endurance of alternating high pressure and temperature, the carbide anvils of the high-press apparatus, which are widely used in the synthetic diamond industry, are prone to crack. In this paper, an acoustic method is used to monitor the crack events, and the intelligent monitoring network is proposed to classify the sound samples. The pulse sound signals produced by such cracking are first extracted based on a short-time energy threshold. Then, the signals are processed with the proposed intelligent monitoring network to identify the operation condition of the anvil of the high-pressure apparatus. The monitoring network is an improved convolutional neural network that solves the problems that may occur in practice. The length of pulse sound excited by the crack growth is variable, so a spatial pyramid pooling layer is adopted to solve the variable-length input problem. An adaptive weighted algorithm for loss function is proposed in this method to handle the class imbalance problem. The good performance regarding the accuracy and balance of the proposed intelligent monitoring network is validated through the experiments finally.

Allozyme Diversity and Morphometrics of Melocactus paucispinus (Cactaceae) and Evidence for Hybridization with M. concinnus in the Chapada Diamantina, North-eastern Brazil

PubMed Central

LAMBERT, SABRINA MOTA; BORBA, EDUARDO LEITE; MACHADO, MARLON CÂMARA; ANDRADE, SÓNIA CRISTINA DA SILVA

2006-01-01

• Background and Aims Melocacatus paucispinus (Cactaceae) is endemic to the state of Bahia, Brazil, and due to its rarity and desirability to collectors it has been considered threatened with extinction. This species is usually sympatric and inter-fertile with M. concinnus, and morphological evidence for hybridization between them is present in some populations. Levels of genetic and morphological variation and sub-structuring in populations of these species were assessed and an attempt was made to verify the occurrence of natural hybridization between them. • Methods Genetic variability was surveyed using allozymes (12 loci) and morphological variability using multivariate morphometric analyses (17 vegetative characters) in ten populations of M. paucispinus and three of M. concinnus occurring in the Chapada Diamantina, Bahia. • Key Results Genetic variability was low in both species (P = 0·0–33·3, A = 1·0–1·6, He = 0·000–0·123 in M. paucispinus; P = 0·0–25·0, A = 1·0–1·4, He = 0·000–0·104 in M. concinnus). Deficit of heterozygotes within the populations was detected in both species, with high values of FIS (0·732 and 0·901 in M. paucispinus and M. concinnus, respectively). Evidence of hybridization was detected by the relative allele frequency in the two diaphorase loci. High levels of genetic (FST = 0·504 in M. paucispinus and 0·349 in M. concinnus) and morphological (A = 0·20 in M. paucispinus and 0·17 in M. concinnus) structuring among populations were found. • Conclusions The Melocactus spp. displayed levels of genetic variability lower than the values reported for other cactus species. The evidence indicates the occurrence of introgression in both species at two sites. The high FST values cannot be explained by geographical substructuring, but are consistent with hybridization. Conversely, morphological differentiation in M. paucispinus, but not in M. concinnus, is probably due to isolation by distance. PMID:16423866

Water clarity in the Florida Keys, USA, as observed from space (1984-2002)

NASA Astrophysics Data System (ADS)

Palandro, D. A.; Hu, C.; Andrefouet, S.; Muller-Karger, F. E.; Hallock, P.

2007-12-01

Landsat TM and ETM+ satellite data were used to derive the diffuse attenuation coefficient (Kd, m-1), a measure of water clarity, for 29 sites throughout the Florida Keys Reef Tract. A total of 28 individual Landsat images between 1984 and 2002 were used, with imagery gathered every two years for spring seasons and every six years for fall seasons. Useful information was obtained by Landsat bands 1 (blue) and 2 (green), except when sites were covered by clouds or showed turbid water. Landsat band 3 (red) provided no consistent data due to the high absorption of red light by water. Because image sampling represented only one or two samples per year on specific days, and because water turbidity may change over short time scales, it was not possible to assess temporal trends at the sites with the Landsat data. Kd values in band 1 were higher in the spring (mean spring = 0.034 m-1, mean fall = 0.031 m-1) and band 2 were higher in the fall (mean spring = 0.056 m-1, mean fall = 0.058 m-1), but the differences were not statistically significant. Spatial variability was high between sites and between regions (Upper, Middle and Lower Keys), with band 1 ranges of 0.019 m-1 - 0.060 m-1 and band 2 ranges of 0.036 m-1 - 0.076 m-1. The highest Kd values were found in the Upper Keys, followed by the Middle Keys and Lower Keys, respectively. This result must be taken in context however, two Middle Keys sites were found to be inconsistent due to high turbidity, obscuring the benthos and altering our assumption of a visible seafloor, which the algorithm is dependent upon. If all Middle Keys data were valid it is likely that this region would have the highest Kd values for both bands. The Landsat-derived Kd values, and inherent variability, may be influenced by the dominant water mass associated with each Florida Keys region, as well as localized oceanic variables. The methodology used here may be applied to other reef areas and used with satellites that offer higher temporal resolution to assess temporal change and variability.

Genetic algorithm based task reordering to improve the performance of batch scheduled massively parallel scientific applications

DOE PAGES

Sankaran, Ramanan; Angel, Jordan; Brown, W. Michael

2015-04-08

The growth in size of networked high performance computers along with novel accelerator-based node architectures has further emphasized the importance of communication efficiency in high performance computing. The world's largest high performance computers are usually operated as shared user facilities due to the costs of acquisition and operation. Applications are scheduled for execution in a shared environment and are placed on nodes that are not necessarily contiguous on the interconnect. Furthermore, the placement of tasks on the nodes allocated by the scheduler is sub-optimal, leading to performance loss and variability. Here, we investigate the impact of task placement on themore » performance of two massively parallel application codes on the Titan supercomputer, a turbulent combustion flow solver (S3D) and a molecular dynamics code (LAMMPS). Benchmark studies show a significant deviation from ideal weak scaling and variability in performance. The inter-task communication distance was determined to be one of the significant contributors to the performance degradation and variability. A genetic algorithm-based parallel optimization technique was used to optimize the task ordering. This technique provides an improved placement of the tasks on the nodes, taking into account the application's communication topology and the system interconnect topology. As a result, application benchmarks after task reordering through genetic algorithm show a significant improvement in performance and reduction in variability, therefore enabling the applications to achieve better time to solution and scalability on Titan during production.« less

Increased variability of watershed areas in patients with high-grade carotid stenosis.

PubMed

Kaczmarz, Stephan; Griese, Vanessa; Preibisch, Christine; Kallmayer, Michael; Helle, Michael; Wustrow, Isabel; Petersen, Esben Thade; Eckstein, Hans-Henning; Zimmer, Claus; Sorg, Christian; Göttler, Jens

2018-03-01

Watershed areas (WSAs) of the brain are most susceptible to acute hypoperfusion due to their peripheral location between vascular territories. Additionally, chronic WSA-related vascular processes underlie cognitive decline especially in patients with cerebral hemodynamic compromise. Despite of high relevance for both clinical diagnostics and research, individual in vivo WSA definition is fairly limited to date. Thus, this study proposes a standardized segmentation approach to delineate individual WSAs by use of time-to-peak (TTP) maps and investigates spatial variability of individual WSAs. We defined individual watershed masks based on relative TTP increases in 30 healthy elderly persons and 28 patients with unilateral, high-grade carotid stenosis, being at risk for watershed-related hemodynamic impairment. Determined WSA location was confirmed by an arterial transit time atlas and individual super-selective arterial spin labeling. We compared spatial variability of WSA probability maps between groups and assessed TTP differences between hemispheres in individual and group-average watershed locations. Patients showed significantly higher spatial variability of WSAs than healthy controls. Perfusion on the side of the stenosis was delayed within individual watershed masks as compared to a watershed template derived from controls, being independent from the grade of the stenosis and collateralization status of the circle of Willis. Results demonstrate feasibility of individual WSA delineation by TTP maps in healthy elderly and carotid stenosis patients. Data indicate necessity of individual segmentation approaches especially in patients with hemodynamic compromise to detect critical regions of impaired hemodynamics.

Tungsten isotopes in bulk meteorites and their inclusions—Implications for processing of presolar components in the solar protoplanetary disk

PubMed Central

Holst, J. C.; Paton, C.; Wielandt, D.; Bizzarro, M.

2016-01-01

We present high precision, low- and high-resolution tungsten isotope measurements of iron meteorites Cape York (IIIAB), Rhine Villa (IIIE), Bendego (IC), and the IVB iron meteorites Tlacotepec, Skookum, and Weaver Mountains, as well as CI chondrite Ivuna, a CV3 chondrite refractory inclusion (CAI BE), and terrestrial standards. Our high precision tungsten isotope data show that the distribution of the rare p-process nuclide 180W is homogeneous among chondrites, iron meteorites, and the refractory inclusion. One exception to this pattern is the IVB iron meteorite group, which displays variable excesses relative to the terrestrial standard, possibly related to decay of rare 184Os. Such anomalies are not the result of analytical artifacts and cannot be caused by sampling of a protoplanetary disk characterized by p-process isotope heterogeneity. In contrast, we find that 183W is variable due to a nucleosynthetic s-process deficit/r-process excess among chondrites and iron meteorites. This variability supports the widespread nucleosynthetic s/r-process heterogeneity in the protoplanetary disk inferred from other isotope systems and we show that W and Ni isotope variability is correlated. Correlated isotope heterogeneity for elements of distinct nucleosynthetic origin (183W and 58Ni) is best explained by thermal processing in the protoplanetary disk during which thermally labile carrier phases are unmixed by vaporization thereby imparting isotope anomalies on the residual processed reservoir. PMID:27445452

SPITZER OBSERVATIONS OF LONG-TERM INFRARED VARIABILITY AMONG YOUNG STELLAR OBJECTS IN CHAMAELEON I

DOE Office of Scientific and Technical Information (OSTI.GOV)

Flaherty, Kevin M.; Herbst, William; DeMarchi, Lindsay

Infrared variability is common among young stellar objects, with surveys finding daily to weekly fluctuations of a few tenths of a magnitude. Space-based observations can produce highly sampled infrared light curves, but are often limited to total baselines of about 1 month due to the orientation of the spacecraft. Here we present observations of the Chameleon I cluster, whose low declination makes it observable by the Spitzer Space Telescope over a 200-day period. We observe 30 young stellar objects with a daily cadence to better sample variability on timescales of months. We find that such variability is common, occurring inmore » ∼80% of the detected cluster members. The change in [3.6]–[4.5] color over 200 days for many of the sources falls between that expected for extinction and fluctuations in disk emission. With our high cadence and long baseline we can derive power spectral density curves covering two orders of magnitude in frequency and find significant power at low frequencies, up to the boundaries of our 200-day survey. Such long timescales are difficult to explain with variations driven by the interaction between the disk and stellar magnetic field, which has a dynamical timescale of days to weeks. The most likely explanation is either structural or temperature fluctuations spread throughout the inner ∼0.5 au of the disk, suggesting that the intrinsic dust structure is highly dynamic.« less

China's water sustainability in the 21st century: a climate-informed water risk assessment covering multi-sector water demands

NASA Astrophysics Data System (ADS)

Chen, X.; Naresh, D.; Upmanu, L.; Hao, Z.; Dong, L.; Ju, Q.; Wang, J.; Wang, S.

2014-05-01

China is facing a water resources crisis with growing concerns as to the reliable supply of water for agricultural, industrial and domestic needs. High inter-annual rainfall variability and increasing consumptive use across the country exacerbates the situation further and is a constraint on future development. For water sustainability, it is necessary to examine the differences in water demand and supply and their spatio-temporal distribution in order to quantify the dimensions of the water risk. Here, a detailed quantitative assessment of water risk as measured by the spatial distribution of cumulated deficits for China is presented. Considering daily precipitation and temperature variability over fifty years and the current water demands, risk measures are developed to inform county level water deficits that account for both within-year and across-year variations in climate. We choose political rather than watershed boundaries since economic activity and water use are organized by county and the political process is best informed through that unit. As expected, the risk measures highlight North China Plain counties as highly water stressed. Regions with high water stress have high inter-annual variability in rainfall and now have depleted groundwater aquifers. The stress components due to agricultural, industrial and domestic water demands are illustrated separately to assess the vulnerability of particular sectors within the country to provide a basis for targeted policy analysis for reducing water stress.

Use of portable exposure meters for comparing mobile phone base station radiation in different types of areas in the cities of Basel and Amsterdam.

PubMed

Urbinello, Damiano; Huss, Anke; Beekhuizen, Johan; Vermeulen, Roel; Röösli, Martin

2014-01-15

Radiofrequency electromagnetic fields (RF-EMF) are highly variable and differ considerably within as well as between areas. Exposure assessment studies characterizing spatial and temporal variation are limited so far. Our objective was to evaluate sources of data variability and the repeatability of daily measurements using portable exposure meters (PEMs). Data were collected at 12 days between November 2010 and January 2011 with PEMs in four different types of urban areas in the cities of Basel (BSL) and Amsterdam (AMS). Exposure from mobile phone base stations ranged from 0.30 to 0.53 V/m in downtown and business areas and in residential areas from 0.09 to 0.41 V/m. Analysis of variance (ANOVA) demonstrated that measurements from various days were highly reproducible (measurement duration of approximately 30 min) with only 0.6% of the variance of all measurements from mobile phone base station radiation being explained by the measurement day and only 0.2% by the measurement time (morning, noon, afternoon), whereas type of area (30%) and city (50%) explained most of the data variability. We conclude that mobile monitoring of exposure from mobile phone base station radiation with PEMs is useful due to the high repeatability of mobile phone base station exposure levels, despite the high spatial variation. © 2013.

Land agroecological quality assessment in conditions of high spatial soil cover variability at the Pereslavskoye Opolye.

NASA Astrophysics Data System (ADS)

Morev, Dmitriy; Vasenev, Ivan

2015-04-01

The essential spatial variability is mutual feature for most natural and man-changed soils at the Central region of European territory of Russia. The original spatial heterogeneity of forest soils has been further complicated by a specific land-use history and human impacts. For demand-driven land-use planning and decision making the quantitative analysis and agroecological interpretation of representative soil cover spatial variability is an important and challenging task that receives increasing attention from private companies, governmental and environmental bodies. Pereslavskoye Opolye is traditionally actively used in agriculture due to dominated high-quality cultivated soddy-podzoluvisols which are relatively reached in organic matter (especially for conditions of the North part at the European territory of Russia). However, the soil cover patterns are often very complicated even within the field that significantly influences on crop yield variability and have to be considered in farming system development and land agroecological quality evaluation. The detailed investigations of soil regimes and mapping of the winter rye yield have been carried in conditions of two representative fields with slopes sharply contrasted both in aspects and degrees. Rye biological productivity and weed infestation have been measured in elementary plots of 0.25 m2 with the following analysis the quality of the yield. In the same plot soil temperature and moisture have been measured by portable devices. Soil sampling was provided from three upper layers by drilling. The results of ray yield detailed mapping shown high differences both in average values and within-field variability on different slopes. In case of low-gradient slope (field 1) there is variability of ray yield from 39.4 to 44.8 dt/ha. In case of expressed slope (field 2) the same species of winter rye grown with the same technology has essentially lower yield and within-field variability from 20 to 29.6 dt/ha. The variability in crop yield between two fields is determined by their differences in mesorelief, A-horizon average thickness and slightly changes in soil temperature. The within-field crop yield variability is determined by microrelief and connected differences in soil moisture. Higher soil cover variability reflects in higher variability of winter ray yield and its quality that could be predicted and planed in conditions of concrete field and year according to principal limiting factors evaluation.

High-resolution rock-magnetic variability in shallow marine sediment: a sensitive paleoclimatic metronome

NASA Astrophysics Data System (ADS)

Arai, Kohsaku; Sakai, Hideo; Konishi, Kenji

1997-05-01

An outer shelf deposit in central Japan centered on the Olduvai normal polarity event in the reversed Matuyama chron reveals a close correlation of both the magnetic susceptibility and remanent intensity with the sedimentary cyclicities apparent in lithologies and molluscan assemblages. Two sedimentary cycles are characterized by distinctly similar, but double-peaked magnetic cyclicities. The rock-magnetic variability is primarily attributed to the relative abundance of terrigenous magnetic minerals, and the double peak of the variability is characterized by the concentration of finer-grained magnetic minerals. The concentration is suspected to be controlled by both climatic change and shifting proximity of the shoreline as a function of rise and fall of the sea level due to glacio-eustasy. Rock-magnetic study reveals the record of a 21 ka period of orbital precession cycles within the sedimentary cyclicity attributable to a 41 ka period of orbital obliquity forcing.

Understanding Empathy, Self-Esteem, and Adult Attachment in Sexual Offenders and Partner-Violent Men.

PubMed

Loinaz, Ismael; Sánchez, Luis Miguel; Vilella, Andrea

2018-02-01

The assessment and treatment of emotional variables is a priority in the rehabilitation of offenders. Although theoretical proposals suggest a clear relationship between violence and self-esteem, attachment, and empathy, the research carried out to date has reached contradictory results due mainly to differences in the measurements used, the reliability of self-reports, or even to problems with the definition of the constructs. The present study analyzed these three variables in a prison sample of sexual offenders ( n = 48) and partner-violent men ( n = 68), using the Interpersonal Reactivity Index, the Rape Empathy Measure, the Rosenberg Self-Esteem Scale, and the Adult Attachment Questionnaire. Results confirmed the low utility of nonspecific empathy, the predominance of high self-esteem, and the difficulty of identifying an insecure attachment. The implications of the use of these variables in the treatment of offenders, and the need to improve the assessment tools, are discussed.

New Measurements of Mars Thermospheric Variability from MAVEN EUVM Solar Occultations

NASA Astrophysics Data System (ADS)

Thiemann, E.; Eparvier, F. G.; Andersson, L.; Pilinski, M.; Chamberlin, P. C.; Fowler, C. M.; Dominique, M.; Bougher, S. W.; Gröller, H.; Girazian, Z.; Lillis, R. J.

2017-12-01

The Mars thermosphere encompasses both the coldest and hottest regions of the Mars neutral atmosphere, where temperatures warm from below 150 K at the well-mixed homopause to 300 K at the collisionless exobase, and change by comparable magnitudes over the diurnal cycle. In this dynamic and highly-structured region, atoms and molecules are accelerated by a number of processes, potentially leading to escape and permanent loss to space. Increasingly, evidence shows that atmospheric escape to space has resulted in the loss of a substantial portion of Mars's atmosphere over the planet's history. Given that the thermosphere is the neutral reservoir for atmospheric escape, understanding how and why it varies is crucial for understanding how Mars's climate has evolved over time. The Mars Atmosphere and Volatile EvolutioN (MAVEN) orbiter's Extreme Ultraviolet (EUV) Monitor (EUVM) has recently demonstrated the capability to measure thermospheric density from 100 to 200 km with solar occultations of its 17-22 nm channel. These measurements are routine, inherently constrained to either 06:00 or 18:00 Local Time, and span all latitudes, a number of which have been revisited multiple times over the past 3 Earth years due to MAVEN's orbital precession. These factors, coupled with uncertainties in retrieved densities below 10%, make MAVEN EUVM occultations ideal for tracking both long-term and latitudinal thermospheric variability. Some notable trends revealed by the EUVM occultation data are variations in poleward warming due to changes in global circulation patterns, planetary-scale waves due to varying gravity wave or tidal forcing, and temperature due to solar EUV variability. In this study, we present these new measurements in detail. We begin by briefly presenting the measurement methods and uncertainties, and show an overview of the measurements made to-date, putting them in the context of observations made by other missions, other instruments onboard MAVEN, and the newly arrived ExoMars Trace Gas Orbiter (TGO). We then show observations of latitudinal and seasonal temperature and density variability made over the MAVEN mission, and discuss the possible underlying causes. We conclude by discussing plans to make these new data publically available as an official MAVEN data product.

Development of process data capturing, analysis and controlling for thermal spray techniques - SprayTracker

NASA Astrophysics Data System (ADS)

Kelber, C.; Marke, S.; Trommler, U.; Rupprecht, C.; Weis, S.

2017-03-01

Thermal spraying processes are becoming increasingly important in high-technology areas, such as automotive engineering and medical technology. The method offers the advantage of a local layer application with different materials and high deposition rates. Challenges in the application of thermal spraying result from the complex interaction of different influencing variables, which can be attributed to the properties of different materials, operating equipment supply, electrical parameters, flow mechanics, plasma physics and automation. In addition, spraying systems are subject to constant wear. Due to the process specification and the high demands on the produced coatings, innovative quality assurance tools are necessary. A central aspect, which has not yet been considered, is the data management in relation to the present measured variables, in particular the spraying system, the handling system, working safety devices and additional measuring sensors. Both the recording of all process-characterizing variables, their linking and evaluation as well as the use of the data for the active process control presuppose a novel, innovative control system (hardware and software) that was to be developed within the scope of the research project. In addition, new measurement methods and sensors are to be developed and qualified in order to improve the process reliability of thermal spraying.

Simulating the Agulhas system in global ocean models - nesting vs. multi-resolution unstructured meshes

NASA Astrophysics Data System (ADS)

Biastoch, Arne; Sein, Dmitry; Durgadoo, Jonathan V.; Wang, Qiang; Danilov, Sergey

2018-01-01

Many questions in ocean and climate modelling require the combined use of high resolution, global coverage and multi-decadal integration length. For this combination, even modern resources limit the use of traditional structured-mesh grids. Here we compare two approaches: A high-resolution grid nested into a global model at coarser resolution (NEMO with AGRIF) and an unstructured-mesh grid (FESOM) which allows to variably enhance resolution where desired. The Agulhas system around South Africa is used as a testcase, providing an energetic interplay of a strong western boundary current and mesoscale dynamics. Its open setting into the horizontal and global overturning circulations also requires global coverage. Both model configurations simulate a reasonable large-scale circulation. Distribution and temporal variability of the wind-driven circulation are quite comparable due to the same atmospheric forcing. However, the overturning circulation differs, owing each model's ability to represent formation and spreading of deep water masses. In terms of regional, high-resolution dynamics, all elements of the Agulhas system are well represented. Owing to the strong nonlinearity in the system, Agulhas Current transports of both configurations and in comparison with observations differ in strength and temporal variability. Similar decadal trends in Agulhas Current transport and Agulhas leakage are linked to the trends in wind forcing.

The prevalence of depression among high school and preuniversity adolescents: Rasht, northern Iran.

PubMed

Modabber-Nia, Mohammad-Jafar; Shodjai-Tehrani, Hossein; Moosavi, Seyed-Roknoddin; Jahanbakhsh-Asli, Nakisa; Fallahi, Mahnaz

2007-04-01

Depression is an important mental health problem, which is quite unknown among adolescents in our community. We conducted this study to determine the prevalence of depression among high school and preuniversity students of Rasht, northern Iran. We studied 4,020 randomly-selected individuals out of 41,815 high school and preuniversity students. Beck's self-administered standard questionnaire and a predetermined form containing some demographic variables were applied to measure variables. Two hundred ninety-nine subjects (due to incomplete responses) and 40 subjects (evening-school students) were excluded from our study. One thousand two hundred fifty (34%: CI 95% 32.4 - 35.4%) out of 3,681 subjects suffered from depression. There were significant differences between the prevalence of depression and type of school (P < 0.001), educational field (P < 0.0005), socioeconomic class (P = 0.0002), and gender (P < 0.001). There was no significant difference between the prevalence of depression and city district, school grade, and age of participants. Our study indicates that depressive symptoms are common in our subjects and they have significant association with low socioeconomic status. We, therefore, recommend the use of psychiatric interview and analytical methods for determination of the prevalence of depressive disorders and its relationship with studied variables.

High-temperature thermal destruction of poultry derived wastes for energy recovery in Australia.

PubMed

Florin, N H; Maddocks, A R; Wood, S; Harris, A T

2009-04-01

The high-temperature thermal destruction of poultry derived wastes (e.g., manure and bedding) for energy recovery is viable in Australia when considering resource availability and equivalent commercial-scale experience in the UK. In this work, we identified and examined the opportunities and risks associated with common thermal destruction techniques, including: volume of waste, costs, technological risks and environmental impacts. Typical poultry waste streams were characterised based on compositional analysis, thermodynamic equilibrium modelling and non-isothermal thermogravimetric analysis coupled with mass spectrometry (TG-MS). Poultry waste is highly variable but otherwise comparable with other biomass fuels. The major technical and operating challenges are associated with this variability in terms of: moisture content, presence of inorganic species and type of litter. This variability is subject to a range of parameters including: type and age of bird, and geographical and seasonal inconsistencies. There are environmental and health considerations associated with combustion and gasification due to the formation of: NO(X), SO(X), H(2)S and HCl gas. Mitigation of these emissions is achievable through correct plant design and operation, however, with significant economic penalty. Based on our analysis and literature data, we present cost estimates for generic poultry-waste-fired power plants with throughputs of 2 and 8 tonnes/h.

Influence of variable water depth and turbidity on microalgae production in a shallow estuarine lake system - A modelling study

NASA Astrophysics Data System (ADS)

Tirok, Katrin; Scharler, Ursula M.

2014-06-01

Strongly varying water levels and turbidities are typical characteristics of the large shallow estuarine lake system of St. Lucia, one of the largest on the African continent. This theoretical study investigated the combined effects of variable water depth and turbidity on seasonal pelagic and benthic microalgae production using a mathematical model, in order to ascertain productivity levels during variable and extreme conditions. Simulated pelagic and benthic net production varied between 0.3 and 180 g C m-2 year-1 and 0 and 220 g C m-2 year-1, respectively, dependent on depth, turbidity, and variability in turbidity. Although not surprising production and biomass decreased with increasing turbidity and depth. A high variability in turbidity, i.e. an alteration of calm and windy days, could reduce or enhance the seasonal pelagic and benthic production by more than 30% compared to a low variability. The day-to-day variability in wind-induced turbidity therefore influences production in the long term. On the other hand, varying water depth within a year did not significantly influence the seasonal production for turbidities representative of Lake St. Lucia. Reduced lake area and volume as observed during dry periods in Lake St. Lucia did not reduce primary production of the entire system since desiccation resulted in lower water depth and thus increased light availability. This agrees with field observations suggesting little light limitation and high areal microalgal biomass during a period with below average rainfall (2005-2011). Thus, microalgae potentially fulfil their function in the lake food-web even under extreme drought conditions. We believe that these results are of general interest to shallow aquatic ecosystems that are sensitive to drought periods due to either human or natural causes.

Importance of physical and hydraulic characteristics to unionid mussels: A retrospective analysis in a reach of large river

USGS Publications Warehouse

Zigler, S.J.; Newton, T.J.; Steuer, J.J.; Bartsch, M.R.; Sauer, J.S.

2008-01-01

Interest in understanding physical and hydraulic factors that might drive distribution and abundance of freshwater mussels has been increasing due to their decline throughout North America. We assessed whether the spatial distribution of unionid mussels could be predicted from physical and hydraulic variables in a reach of the Upper Mississippi River. Classification and regression tree (CART) models were constructed using mussel data compiled from various sources and explanatory variables derived from GIS coverages. Prediction success of CART models for presence-absence of mussels ranged from 71 to 76% across three gears (brail, sled-dredge, and dive-quadrat) and 51% of the deviance in abundance. Models were largely driven by shear stress and substrate stability variables, but interactions with simple physical variables, especially slope, were also important. Geospatial models, which were based on tree model results, predicted few mussels in poorly connected backwater areas (e.g., floodplain lakes) and the navigation channel, whereas main channel border areas with high geomorphic complexity (e.g., river bends, islands, side channel entrances) and small side channels were typically favorable to mussels. Moreover, bootstrap aggregation of discharge-specific regression tree models of dive-quadrat data indicated that variables measured at low discharge were about 25% more predictive (PMSE = 14.8) than variables measured at median discharge (PMSE = 20.4) with high discharge (PMSE = 17.1) variables intermediate. This result suggests that episodic events such as droughts and floods were important in structuring mussel distributions. Although the substantial mussel and ancillary data in our study reach is unusual, our approach to develop exploratory statistical and geospatial models should be useful even when data are more limited. ?? 2007 Springer Science+Business Media B.V.

Characterization of the Infrared/X-ray sub-second variability for the black-hole transient GX 339-4

NASA Astrophysics Data System (ADS)

Vincentelli, F. M.; Casella, P.; Maccarone, T. J.; Uttley, P.; Gandhi, P.; Belloni, T.; De Marco, B.; Russell, D. M.; Stella, L.; O'Brien, K.

2018-03-01

We present a detailed analysis of the X-ray/IR fast variability of the Black-Hole Transient GX 339-4 during its low/hard state in August 2008. Thanks to simultaneous high time-resolution observations made with the VLT and RXTE, we performed the first characterisation of the sub-second variability in the near-infrared band - and of its correlation with the X-rays - for a low-mass X-ray binary, using both time- and frequency-domain techniques. We found a power-law correlation between the X-ray and infrared fluxes when measured on timescales of 16 seconds, with a marginally variable slope, steeper than the one found on timescales of days at similar flux levels. We suggest the variable slope - if confirmed - could be due to the infrared flux being a non-constant combination of both optically thin and optically thick synchrotron emission from the jet, as a result of a variable self-absorption break. From cross spectral analysis we found an approximately constant infrared time lag of ≈0.1s, and a very high coherence of ˜90 per cent on timescales of tens of seconds, slowly decreasing toward higher frequencies. Finally, we report on the first detection of a linear rms-flux relation in the emission from a low-mass X-ray binary jet, on timescales where little correlation is found between the X-rays and the jet emission itself. This suggests that either the inflow variations and jet IR emission are coupled by a non-linear or time-variable transform, or that the IR rms-flux relation is not transferred from the inflow to the jet, but is an intrinsic property of emission processes in the jet.

Characterization of the infrared/X-ray subsecond variability for the black hole transient GX 339-4

NASA Astrophysics Data System (ADS)

Vincentelli, F. M.; Casella, P.; Maccarone, T. J.; Uttley, P.; Gandhi, P.; Belloni, T.; De Marco, B.; Russell, D. M.; Stella, L.; O'Brien, K.

2018-07-01

We present a detailed analysis of the X-ray/IR fast variability of the Black-Hole Transient GX 339-4 during its low/hard state in 2008 August. Thanks to simultaneous high time resolution observations made with the VLT and RXTE, we performed the first characterization of the subsecond variability in the near-infrared band - and of its correlation with the X-rays - for a low-mass X-ray binary, using both time- and frequency-domain techniques. We found a power-law correlation between the X-ray and infrared fluxes when measured on time-scales of 16 s, with a marginally variable slope, steeper than the one found on time-scales of days at similar flux levels. We suggest the variable slope - if confirmed - could be due to the infrared flux being a non-constant combination of both optically thin and optically thick synchrotron emission from the jet, as a result of a variable self-absorption break. From cross spectral analysis, we found an approximately constant infrared time lag of ≈0.1 s, and a very high coherence of ˜90 per cent on time-scales of tens of seconds, slowly decreasing towards higher frequencies. Finally, we report on the first detection of a linear rms-flux relation in the emission from a low-mass X-ray binary jet, on time-scales where little correlation is found between the X-rays and the jet emission itself. This suggests that either the inflow variations and jet IR emission are coupled by a non-linear or time-variable transform, or that the IR rms-flux relation is not transferred from the inflow to the jet, but is an intrinsic property of emission processes in the jet.

The Spatial and Temporal Variability of Meltwater Flow Paths: Insights From a Grid of Over 100 Snow Lysimeters

NASA Astrophysics Data System (ADS)

Webb, R. W.; Williams, M. W.; Erickson, T. A.

2018-02-01

Snowmelt is an important part of the hydrologic cycle and ecosystem dynamics for headwater systems. However, the physical process of water flow through snow is a poorly understood aspect of snow hydrology as meltwater flow paths tend to be highly complex. Meltwater flow paths diverge and converge as percolating meltwater reaches stratigraphic layer interfaces creating high spatial variability. Additionally, a snowpack is temporally heterogeneous due to rapid localized metamorphism that occurs during melt. This study uses a snowmelt lysimeter array at tree line in the Niwot Ridge study area of northern Colorado. The array is designed to address the issue of spatial and temporal variability of basal discharge at 105 locations over an area of 1,300 m2. Observed coefficients of variation ranged from 0 to almost 10 indicating more variability than previously observed, though this variability decreased throughout each melt season. Snowmelt basal discharge also significantly increases as snow depth decreases displaying a cluster pattern that peaks during weeks 3-5 of the snowmelt season. These results are explained by the flow of meltwater along snow layer interfaces. As the snowpack becomes less stratified through the melt season, the pattern transforms from preferential flow paths to uniform matrix flow. Correlation ranges of the observed basal discharge correspond to a mean representative elementary area of 100 m2, or a characteristic length of 10 m. Snowmelt models representing processes at scales less than this will need to explicitly incorporate the spatial variability of snowmelt discharge and meltwater flow paths through snow between model pixels.

Association between climate variability and malaria epidemics in the East African highlands.

PubMed

Zhou, Guofa; Minakawa, Noboru; Githeko, Andrew K; Yan, Guiyun

2004-02-24

The causes of the recent reemergence of Plasmodium falciparum epidemic malaria in the East African highlands are controversial. Regional climate changes have been invoked as a major factor; however, assessing the impact of climate in malaria resurgence is difficult due to high spatial and temporal climate variability and the lack of long-term data series on malaria cases from different sites. Climate variability, defined as short-term fluctuations around the mean climate state, may be epidemiologically more relevant than mean temperature change, but its effects on malaria epidemics have not been rigorously examined. Here we used nonlinear mixed-regression model to investigate the association between autoregression (number of malaria outpatients during the previous time period), seasonality and climate variability, and the number of monthly malaria outpatients of the past 10-20 years in seven highland sites in East Africa. The model explained 65-81% of the variance in the number of monthly malaria outpatients. Nonlinear and synergistic effects of temperature and rainfall on the number of malaria outpatients were found in all seven sites. The net variance in the number of monthly malaria outpatients caused by autoregression and seasonality varied among sites and ranged from 18 to 63% (mean=38.6%), whereas 12-63% (mean=36.1%) of variance is attributed to climate variability. Our results suggest that there was a high spatial variation in the sensitivity of malaria outpatient number to climate fluctuations in the highlands, and that climate variability played an important role in initiating malaria epidemics in the East African highlands.

First light: exploring the spectra of high-redshift galaxies in the Renaissance Simulations

NASA Astrophysics Data System (ADS)

Barrow, Kirk S. S.; Wise, John H.; Norman, Michael L.; O'Shea, Brian W.; Xu, Hao

2017-08-01

We present synthetic observations for the first generations of galaxies in the Universe and make predictions for future deep field observations for redshifts greater than 6. Due to the strong impact of nebular emission lines and the relatively compact scale of H II regions, high-resolution cosmological simulations and a robust suite of analysis tools are required to properly simulate spectra. We created a software pipeline consisting of fsps, hyperion, cloudy and our own tools to generate synthetic IR observations from a fully three-dimensional arrangement of gas, dust, and stars. Our prescription allows us to include emission lines for a complete chemical network and tackle the effect of dust extinction and scattering in the various lines of sight. We provide spectra, 2D binned photon imagery for both HST and JWST IR filters, luminosity relationships, and emission-line strengths for a large sample of high-redshift galaxies in the Renaissance Simulations. Our resulting synthetic spectra show high variability between galactic haloes with a strong dependence on stellar mass, metallicity, gas mass fraction, and formation history. Haloes with the lowest stellar mass have the greatest variability in [O III]/Hβ, [O III], and C III], while haloes with higher masses are seen to show consistency in their spectra and [O III] equivalent widths between 1 and 10 Å. Viewing angle accounted for threefold difference in flux due to the presence of ionized gas channels in a halo. Furthermore, JWST colour plots show a discernible relationship between redshift, colour, and mean stellar age.

The MASIV Survey - IV. Relationship between intra-day scintillation and intrinsic variability of radio AGNs

NASA Astrophysics Data System (ADS)

Koay, J. Y.; Macquart, J.-P.; Jauncey, D. L.; Pursimo, T.; Giroletti, M.; Bignall, H. E.; Lovell, J. E. J.; Rickett, B. J.; Kedziora-Chudczer, L.; Ojha, R.; Reynolds, C.

2018-03-01

We investigate the relationship between 5 GHz interstellar scintillation (ISS) and 15 GHz intrinsic variability of compact, radio-selected active galactic nuclei (AGNs) drawn from the Microarcsecond Scintillation-Induced Variability (MASIV) Survey and the Owens Valley Radio Observatory blazar monitoring program. We discover that the strongest scintillators at 5 GHz (modulation index, m5 ≥ 0.02) all exhibit strong 15 GHz intrinsic variability (m15 ≥ 0.1). This relationship can be attributed mainly to the mutual dependence of intrinsic variability and ISS amplitudes on radio core compactness at ˜ 100 μas scales, and to a lesser extent, on their mutual dependences on source flux density, arcsec-scale core dominance and redshift. However, not all sources displaying strong intrinsic variations show high amplitude scintillation, since ISS is also strongly dependent on Galactic line-of-sight scattering properties. This observed relationship between intrinsic variability and ISS highlights the importance of optimizing the observing frequency, cadence, timespan and sky coverage of future radio variability surveys, such that these two effects can be better distinguished to study the underlying physics. For the full MASIV sample, we find that Fermi-detected gamma-ray loud sources exhibit significantly higher 5 GHz ISS amplitudes than gamma-ray quiet sources. This relationship is weaker than the known correlation between gamma-ray loudness and the 15 GHz variability amplitudes, most likely due to jet opacity effects.

A geostatistical analysis of small-scale spatial variability in bacterial abundance and community structure in salt marsh creek bank sediments

NASA Technical Reports Server (NTRS)

Franklin, Rima B.; Blum, Linda K.; McComb, Alison C.; Mills, Aaron L.

2002-01-01

Small-scale variations in bacterial abundance and community structure were examined in salt marsh sediments from Virginia's eastern shore. Samples were collected at 5 cm intervals (horizontally) along a 50 cm elevation gradient, over a 215 cm horizontal transect. For each sample, bacterial abundance was determined using acridine orange direct counts and community structure was analyzed using randomly amplified polymorphic DNA fingerprinting of whole-community DNA extracts. A geostatistical analysis was used to determine the degree of spatial autocorrelation among the samples, for each variable and each direction (horizontal and vertical). The proportion of variance in bacterial abundance that could be accounted for by the spatial model was quite high (vertical: 60%, horizontal: 73%); significant autocorrelation was found among samples separated by 25 cm in the vertical direction and up to 115 cm horizontally. In contrast, most of the variability in community structure was not accounted for by simply considering the spatial separation of samples (vertical: 11%, horizontal: 22%), and must reflect variability from other parameters (e.g., variation at other spatial scales, experimental error, or environmental heterogeneity). Microbial community patch size based upon overall similarity in community structure varied between 17 cm (vertical) and 35 cm (horizontal). Overall, variability due to horizontal position (distance from the creek bank) was much smaller than that due to vertical position (elevation) for both community properties assayed. This suggests that processes more correlated with elevation (e.g., drainage and redox potential) vary at a smaller scale (therefore producing smaller patch sizes) than processes controlled by distance from the creek bank. c2002 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.

The x ray variability of NGC6814: Power spectra

NASA Technical Reports Server (NTRS)

Done, C.; Madejski, G. M.; Mushotsky, R. F.; Turner, T. J.; Koyama, K.; Kunieda, H.

1992-01-01

Simulation techniques are used to obtain the X-ray variability power spectrum of unevenly sampled GINGA data from NGC6814. A simple power law is not an adequate description of the power spectrum, with the residuals showing excess power on timescales consistent with the periodicity seen in EXOSAT observations of this object. However the shape of the folded lightcurve is very different, with 3 main peaks, two of which are separated by an extremely sharp dip instead of the single peak and small harmonic structure observed by EXOSAT. Using the dip as a fiducial mark, a second GINGA observation of this source taken one year later is found to be consistent with being completely periodic and phase coherent with this first GINGA observation. Thus the period is consistent with being constant over a period of 6 years, but phase coherence is only maintained on timescales of approximately 1 year. Over 75 percent of the total source variability is due to the periodic component (r.m.s. amplitude of 36 percent). The residual variability can be described as the more usual 'flicker noise' f(exp -1.1) powerlaw. This shows no apparent high frequency break on timescales greater than 300 seconds. Subtle differences in the shape of the folded light curve with energy, and the very large amount of power in the periodic component suggest occultation as its origin, though amplification of variability from an X-ray emitting 'hot spot' at the disk inner radius through gravitational lensing is also possible. The former suffers from the very arbitrary nature of the periodic timescale, while the latter is unattractive as it cannot simply explain the lack of high frequency break in the residual power. That these models probably fail to provide an adequate explanation may be due to the added complexity of anisotropy of the X-ray emission, suggested by the discrepancy between the lack of soft photons implied by the flat spectrum and the copious source of soft photons available from reprocessing in the iron line producing material.

Southern Ocean Convection and tropical telleconnections

NASA Astrophysics Data System (ADS)

Marinov, I.; Cabre, A.; Gnanadesikan, A.

2014-12-01

We show that Southern Ocean (SO) temperatures in the latest generation of Earth System Models exhibit two major modes of variation, one driven by deep convection, the other by tropical variability. We perform a CMIP5 model intercomparison to understand why different climate models represent SO variability so differently in long, control simulations. We show that multiyear variability in Southern Ocean sea surface temperatures (SSTs) can in turn influence oceanic and atmospheric conditions in the tropics on short (atmospheric) time-scales. We argue that the strength and pattern of SO-tropical teleconnections depends on the intensity of SO deep convection. Periodic convection in the SO is a feature of most CMIP5 models under preindustrial forcing (deLavergne et al., 2014). Models show a wide distribution in the spatial extent, periodicity and intensity of their SO convection, with some models convecting most of the time, and some showing very little convection. In a highly convective coupled model, we find that multidecadal variability in SO and global SSTs, as well as SO heat storage are driven by Weddell Sea convective variability, with convective decades relatively warm due to the heat released from the deep southern ocean and non-convective decades cold due to the subsurface storage of heat. Furthermore, pulses of SO convection drive SST and sea ice variations, influencing absorbed shortwave and emitted longwave radiation, wind, cloud and precipitation patterns, with climatic implications for the low latitudes via fast atmospheric teleconnections. We suggest that these high-low latitude teleconnection mechanisms are relevant for understanding hiatus decades. Additionally, Southern Ocean deep convection varied significantly during past, natural climate changes such as during the last deglaciation. Weddell Sea open convection was recently weakened, likely as a consequence of anthropogenic forcing and the resulting surface freshening. Our study opens up the tantalizing possibility that such large-scale changes in SO deep convection might have tropical and indeed global implications via atmospheric teleconnections. We advocate the collection of both paleo and modern proxies that can verify these model-derived mechanisms and global teleconnections.

Mental models of audit and feedback in primary care settings.

PubMed

Hysong, Sylvia J; Smitham, Kristen; SoRelle, Richard; Amspoker, Amber; Hughes, Ashley M; Haidet, Paul

2018-05-30

Audit and feedback has been shown to be instrumental in improving quality of care, particularly in outpatient settings. The mental model individuals and organizations hold regarding audit and feedback can moderate its effectiveness, yet this has received limited study in the quality improvement literature. In this study we sought to uncover patterns in mental models of current feedback practices within high- and low-performing healthcare facilities. We purposively sampled 16 geographically dispersed VA hospitals based on high and low performance on a set of chronic and preventive care measures. We interviewed up to 4 personnel from each location (n = 48) to determine the facility's receptivity to audit and feedback practices. Interview transcripts were analyzed via content and framework analysis to identify emergent themes. We found high variability in the mental models of audit and feedback, which we organized into positive and negative themes. We were unable to associate mental models of audit and feedback with clinical performance due to high variance in facility performance over time. Positive mental models exhibit perceived utility of audit and feedback practices in improving performance; whereas, negative mental models did not. Results speak to the variability of mental models of feedback, highlighting how facilities perceive current audit and feedback practices. Findings are consistent with prior research  in that variability in feedback mental models is associated with lower performance.; Future research should seek to empirically link mental models revealed in this paper to high and low levels of clinical performance.

Ammonia and Methane Dairy Emission Plumes in the San Joaquin Valley of California from Individual Feedlot to Regional Scales

NASA Technical Reports Server (NTRS)

Miller, David J.; Sun, Kang; Pan, Da; Zondlo, Mark A.; Nowak, John B.; Liu, Zhen; Diskin, Glenn; Sachse, Glen; Beyersdorf, Andreas; Ferrare, Richard;

Ammonia and methane dairy emissions in the San Joaquin Valley of California from individual feedlot to regional scale

DOE PAGES

Miller, David J.; Sun, Kang; Tao, Lei; ...

2015-09-27

Agricultural ammonia (NH 3) emissions are highly uncertain, with high spatiotemporal variability and a lack of widespread in situ measurements. Regional NH 3 emission estimates using mass balance or emission ratio approaches are uncertain due to variable NH 3 sources and sinks as well as unknown plume correlations with other dairy source tracers. We characterize the spatial distributions of NH 3 and methane (CH 4) dairy plumes using in situ surface and airborne measurements in the Tulare dairy feedlot region of the San Joaquin Valley, California, during the NASA Deriving Information on Surface conditions from Column and Vertically Resolved Observationsmore » Relevant to Air Quality 2013 field campaign. Surface NH 3 and CH 4 mixing ratios exhibit large variability with maxima localized downwind of individual dairy feedlots. The geometric mean NH 3:CH 4 enhancement ratio derived from surface measurements is 0.15 ± 0.03 ppmv ppmv –1. Individual dairy feedlots with spatially distinct NH 3 and CH 4 source pathways led to statistically significant correlations between NH 3 and CH 4 in 68% of the 69 downwind plumes sampled. At longer sampling distances, the NH 3:CH 4 enhancement ratio decreases 20–30%, suggesting the potential for NH 3 deposition as a loss term for plumes within a few kilometers downwind of feedlots. Aircraft boundary layer transect measurements directly above surface mobile measurements in the dairy region show comparable gradients and geometric mean enhancement ratios within measurement uncertainties, even when including NH 3 partitioning to submicron particles. Individual NH 3 and CH 4 plumes sampled at close proximity where losses are minimal are not necessarily correlated due to lack of mixing and distinct source pathways. As a result, our analyses have important implications for constraining NH 3 sink and plume variability influences on regional NH 3 emission estimates and for improving NH 3 emission inventory spatial allocations.« less

Severe flooding along the eastern Adriatic coast: the case of 1 December 2008

NASA Astrophysics Data System (ADS)

Međugorac, Iva; Pasarić, Miroslava; Orlić, Mirko

2015-06-01

This paper addresses an extraordinary storm surge in the Northern Adriatic that was more pronounced on the eastern than on the western shore. On 1 December 2008, Adriatic monitoring stations detected exceptionally high sea levels; the oldest Croatian tide gauge station recorded the highest water level in its operating history at the time. Apart from the Northern Adriatic, large portion of the Dalmatian Coast was also exposed to high water levels, while Venice experienced a less-dramatic event. This marine storm was different from the capital storm of 4 November 1966 during which the surge had the highest impact ahead of Venice and along the north-western coastline. The 2008 event is studied here in detail, and the mechanisms that resulted in the different flooding of the two shores are identified. The study is based on hourly sea level, air pressure and wind data measured along both basin sides together with ECMWF reanalysis fields. Four components of sea-level evolution are identified: the storm surge, tide, Adriatic seiche and, low-frequency variability. The 2008 event was the outcome of a fine interplay between the first three components, which were all superimposed on the raised sea level due to low-frequency variability. The marine storm differed from the 1966 storm in the atmospheric forcing and relative timing of all contributing processes. The 2008 flooding of the eastern coast was mainly due to the Sirocco-wind shear, whereas the 1966 flooding of the western coast was due to the combined effect of almost uniform Sirocco and bottom slope.

Heart rate variabilty changes during first week of acclimatization to 3500 m altitude in Indian military personnel.

PubMed

Bhaumik, G; Dass, D; Bhattacharyya, D; Sharma, Y K; Singh, S B

2013-01-01

Acute exposure to hypobaric hypoxia induces the changes in autonomic control of heart rate. Due to emergencies or war like conditions, rapid deployment of Indian military personnel into high altitude frequently occurs. Rapid deployment to high altitude soldiers are at risk of developing high altitude sickness. The present study was conducted to evaluate the acute exposure to high altitude hypobaric hypoxia (3500 m altitude) on the autonomic nervous control of heart rate in Indian military personnel during first week of acclimatization Indices of heart rate variability (viz; R-R interval, total power, low frequency, high frequency, ratio of low to high frequency) and pulse arterial oxygen saturation were measured at sea level and 3500m altitude. Power spectrum of heart rate variability was quantified by low frequency (LF: 0.04-0.15 Hz) and high frequency (HF: 0.15-0.5 Hz) widths. The ratio of LF to HF was also assessed as an index of the sympathovagal balance. Mean R-R interval decreased significantly on day 2 on induction to altitude which tended to increase on day 5. Total power (TP) decreased high altitude and tended to recover within a week. Both HF and LF power showed decrement at 3500m in comparison to sea level. The ratio of LF to HF (LF/HF) at 3500m was significantly higher at 3500m. SpO2 values decreased significantly (P < 0.05) at high altitude on day-2 which increased on day-5. We conclude that autonomic control of the heart rate measured by heart rate variability was altered on acute induction to 3500m which showed a significant decrease in parasympathetic tone and increase in sympathetic tone, then acclimatization seems to be characterized by progressive shift toward a higher parasympathetic tone.

Variable velocity in solar external receivers

NASA Astrophysics Data System (ADS)

Rodríguez-Sánchez, M. R.; Sánchez-González, A.; Acosta-Iborra, A.; Santana, D.

2017-06-01

One of the major problems in solar external receivers is tube overheating, which accelerates the risk of receiver failure. It can be solved implementing receivers with high number of panels. However, it exponentially increases the pressure drop in the receiver and the parasitic power consumption of the Solar Power Tower (SPT), reducing the global efficiency of the SPT. A new concept of solar external receiver, named variable velocity receiver, is able to adapt their configuration to the different flux density distributions. A set of valves allows splitting in several independent panels those panels in which the wall temperature is over the limit. It increases the velocity of the heat transfer fluid (HTF) and its cooling capacity. This receiver does not only reduce the wall temperature of the tubes, but also simplifies the control of the heliostat field and allows to employ more efficient aiming strategies. In this study, it has been shown that variable velocity receiver presents high advantages with respect to traditional receiver. Nevertheless, more than two divisions per panels are not recommendable, due to the increment of the pressure drop over 70 bars. In the design point (12 h of the Spring Equinox), the use of a variable number of panels between 18 and 36 (two divisions per panel), in a SPT similar to Gemasolar, improves the power capacity of the SPT in 5.7%, with a pressure drop increment of 10 bars. Off-design, when the flux distribution is high and not symmetric (e.g. 10-11 h), the power generated by the variable velocity receiver is 18% higher than the generated by the traditional receiver, at these hours the pressure drop increases almost 20 bars.

Constancy despite variability: Local and regional macrofaunal diversity in intertidal seagrass beds

NASA Astrophysics Data System (ADS)

Boyé, Aurélien; Legendre, Pierre; Grall, Jacques; Gauthier, Olivier

2017-12-01

The importance of seagrass habitat for the diversity of benthic fauna has been extensively studied worldwide. Most of the information available is, however, about α diversity while little consideration has been given to β diversity. To fill the knowledge gaps regarding the variability of epifaunal and infaunal seagrass assemblages at large spatial and temporal scales, we scrutinized an extensive dataset covering five years of monitoring of eight intertidal Zostera marina meadows around Brittany (France). High species richness arose at the regional scale from the combination of high local diversity of the meadows and substantial among-meadows β diversity. Epifauna and infauna appeared as distinct self-communities as they displayed different spatial and temporal patterns and varied in their responses to local hydrological conditions. Infauna had higher total β diversity than epifauna due to a tighter link to the great variability of local environmental conditions in the region. Both exhibited substantial variations in species composition and community structure with variations of dominant species that were accompanied by extensive change in numerous rare species. The dominant epifaunal species were all grazers. Changes in species composition were induced mostly by species replacement and rarely by richness differences between meadows. Indeed, species richness remained within a narrow range for all seagrass beds, suggesting a potential carrying capacity for species richness of the meadows. Overall, all meadows contributed equally to the regional turnover of seagrass macrofauna, emphasizing high variability and complementarity among beds at the regional scale. The implications of this substantial within-seagrass variability for the functioning of benthic ecosystems at broad scale and for conservation purposes in habitat mosaics warrant further investigations but our results clearly advocate taking into account within-habitat variation when evaluating the diversity of benthic habitats and the potential effect of habitat loss.

Observed Cloud Properties Above the Northern Indian Ocean During CARDEX 2012

NASA Astrophysics Data System (ADS)

Gao, L.; Wilcox, E. M.

2016-12-01

An analysis of cloud microphysical, macrophysical and radiative properties during the dry winter monsoon season above the northern Indian Ocean is presented. The Cloud Aerosol Radiative Forcing Experiment (CARDEX), conducted from 16 February to 30 March 2012 at the Maldives Climate Observatory on Hanimaadhoo (MCOH), used autonomous unmanned aerial vehicles (UAVs) to measure the aerosol profiles, water vapor flux and cloud properties concurrent with continuous ground measurements of surface aerosol and meteorological variables as well as the total-column precipitable water vapor (PWV) and the cloud liquid water path (LWP). Here we present the cloud properties only for the cases with lower atmospheric water vapor using the criterion that the PWV less than 40 kg/m2. This criterion acts to filter the data to control for the natural meteorological variability in the region according to previous studies. The high polluted case is found to correlate with warmer temperature, higher relative humidity in boundary layer and lower lifted condensation level (LCL). Micro Pulse Lidar (MPL) retrieved cloud base height coincides with calculated LCL height which is lower for high polluted case. Meanwhile satellite retrieved cloud top height didn't show obvious variation indicating cloud deepening which is consistent with the observed greater cloud LWP in high polluted case. Those high polluted clouds are associated with more cloud droplets and smaller effective radius and are generally becoming narrower due to the stronger cloud side evaporation-entrainment effect and becoming deeper due to more moist static energy. Clouds in high polluted condition become brighter with higher albedo which can cause a net shortwave forcing over -40 W/m2 in this region.

Suspended-Sediment Impacts on Light-limited Productivity in the Delaware Estuary

NASA Astrophysics Data System (ADS)

McSweeney, J.; Chant, R. J.; Wilkin, J.; Sommerfield, C. K.

2016-12-01

The Delaware Estuary has a history of high anthropogenic nutrient loadings, but has been classified as a high-nutrient, low-growth system due persistent light limitations caused by turbidity. While the biogeochemical implications of light limitation in turbid estuaries has been well-studied, there has been minimal effort focused on the connectivity between hydrodynamics, sediment dynamics, and light-limitation. Our understanding of sediment dynamics in the Delaware Estuary has advanced significantly in the last decade, and this study provides insight about how the spatiotemporal variability of the estuarine turbidity maximum controls the light available for primary productivity. This analysis uses data from eight along-estuary cruises from March, June, September, and December 2010 and 2011 to look at the seasonality of suspended sediment and chlorophyll distributions. By estimating the absorption due to sediment under a range of environmental conditions, we describe how the movement of the turbidity maximum affects light availability. We also use an idealized 2-dimensional Regional Ocean Modeling System (ROMS) numerical model to evaluate how river discharge and spring-neap variability modulate the location of phytoplankton blooms. We conclude that high river flows and neap tides can drive stratification that is strong enough to prevent sediment from being resuspended into the surface layer, thus providing light conditions favorable for primary productivity. This study sheds light on the importance of sediment in the limiting primary productivity, and the role of stratification in promoting production, highlighting the potential limitations of biogeochemical models that do not account for sediment absorption.

Factors affecting the age-C resident fish community along shorelines of the Hanford Reach of the Columbia River

USGS Publications Warehouse

Gadomski, D.M.; Wagner, P.G.

2009-01-01

The Hanford Reach is one of the few remaining unimpounded sections of the Columbia River. However, because of flow management at upstream dams, there are often large fluctuations in water level. To determine how environmental conditions might affect age-0 resident fishes in the Hanford Reach, we evaluated species composition, distribution, abundance, and standard lengths of larval and juvenile fishes along shoreline habitats during July and August 1998, 1999, and 2000. Catches in beach seine hauls during all three years were highly variable. The four most abundant taxa collected were three cyprinids, peamouth (Mylocheilus caurinus), northern pikeminnow (Plychocheilus oregonensis), and redside shiner (Richardson ius balteatus); and suckers (Catostoinus spp.). Highest overall catches were in sloughs of the Hanford Reach in 1999, a year with high flows, lower water level fluctuations, and more vegetation. Mean shoreline summer water temperatures were higher in 1998 than in 1999 and 2000, and mean lengths of the four most abundant taxa in late August were also greater in 1998, due presumably to enhanced growth or an earlier spawning season. In spite of flow fluctuations, overall catches of age-0 resident fishes were greater in the riverine Hanford Reach compared to past catches in a more lentic Columbia River reservoir. High abundances of age-0 resident fishes in the Hanford Reach could be due to more spawning and rearing habitat in this structurally complex area, and may mitigate for negative effects of variable flow regimes.

Variability of Carotenoid Biosynthesis in Orange Colored Capsicum spp.

PubMed Central

Guzman, Ivette; Hamby, Shane; Romero, Joslynn; Bosland, Paul W.; O’Connell, Mary A.

2010-01-01

Pepper, Capsicum spp., is a worldwide crop valued for heat, nutrition, and rich pigment content. Carotenoids, the largest group of plant pigments, function as antioxidants and as vitamin A precursors. The most abundant carotenoids in ripe pepper fruits are β-carotene, capsanthin, and capsorubin. In this study, the carotenoid composition of orange fruited Capsicum lines was defined along with the allelic variability of the biosynthetic enzymes. The carotenoid chemical profiles present in seven orange pepper varieties were determined using a novel UPLC method. The orange appearance of the fruit was due either to the accumulation of β-carotene, or in two cases, due to only the accumulation of red and yellow carotenoids. Four carotenoid biosynthetic genes, Psy, Lcyb, CrtZ-2, and Ccs were cloned and sequenced from these cultivars. This data tested the hypothesis that different alleles for specific carotenoid biosynthetic enzymes are associated with specific carotenoid profiles in orange peppers. While the coding regions within Psy and CrtZ-2 did not change in any of the lines, the genomic sequence contained introns not previously reported. Lcyb and Ccs contained no introns but did exhibit polymorphisms resulting in amino acid changes; a new Ccs variant was found. When selectively breeding for high provitamin A levels, phenotypic recurrent selection based on fruit color is not sufficient, carotenoid chemical composition should also be conducted. Based on these results, specific alleles are candidate molecular markers for selection of orange pepper lines with high β-carotene and therefore high pro-vitamin A levels. PMID:20582146

Confronting the demand and supply of snow seasonal forecasts for ski resorts : the case of French Alps

NASA Astrophysics Data System (ADS)

Dubois, Ghislain

2017-04-01

Alpine ski resorts are highly dependent on snow, which availability is characterized by a both a high inter-annual variability and a gradual diminution due to climate change. Due to this dependency to climatic resources, the ski industry is increasingly affected by climate change: higher temperatures limit snow falls, increase melting and limit the possibilities of technical snow making. Therefore, since the seventies, managers drastically improved their practices, both to adapt to climate change and to this inter-annual variability of snow conditions. Through slope preparation and maintenance, snow stock management, artificial snow making, a typical resort can approximately keep the same season duration with 30% less snow. The ski industry became an activity of high technicity The EUPORIAS FP7 (www.euporias.eu) project developed between 2012 and 2016 a deep understanding of the supply and demand conditions for the provision of climate services disseminating seasonal forecasts. In particular, we developed a case study, which allowed conducting several activities for a better understanding of the demand and of the business model of future services applied to the ski industry. The investigations conducted in France inventoried the existing tools and databases, assessed the decision making process and data needs of ski operators, and provided evidences that some discernable skill of seasonal forecasts exist. This case study formed the basis of the recently funded PROSNOW H2020 project. We will present the main results of EUPORIAS project for the ski industry.

A new high resolution permafrost map of Iceland from Earth Observation data

NASA Astrophysics Data System (ADS)

Barnie, Talfan; Conway, Susan; Balme, Matt; Graham, Alastair

2017-04-01

High resolution maps of permafrost are required for ongoing monitoring of environmental change and the resulting hazards to ecosystems, people and infrastructure. However, permafrost maps are difficult to construct - direct observations require maintaining networks of sensors and boreholes in harsh environments and are thus limited in extent in space and time, and indirect observations require models or assumptions relating the measurements (e.g. weather station air temperature, basal snow temperature) to ground temperature. Operationally produced Land Surface Temperature maps from Earth Observation data can be used to make spatially contiguous estimates of mean annual skin temperature, which has been used a proxy for the presence of permafrost. However these maps are subject to biases due to (i) selective sampling during the day due to limited satellite overpass times, (ii) selective sampling over the year due to seasonally varying cloud cover, (iii) selective sampling of LST only during clearsky conditions, (iv) errors in cloud masking (v) errors in temperature emissivity separation (vi) smoothing over spatial variability. In this study we attempt to compensate for some of these problems using a bayesian modelling approach and high resolution topography-based downscaling.

Posture and re-positioning considerations of a complete torso topographic analysis system for assessing scoliosis

NASA Astrophysics Data System (ADS)

Ajemba, Peter O.; Durdle, Nelson G.; Hill, Doug L.; Raso, V. J.

2006-02-01

The influence of posture and re-positioning (sway and breathing) on the accuracy of a torso imaging system for assessing scoliosis was evaluated. The system comprised of a rotating positioning platform and one or two laser digitizers. It required four partial-scans taken at 90 ° intervals over 10 seconds to generate two complete torso scans. Its accuracy was previously determined to be 1.1+/-0.9mm. Ten evenly spaced cross-sections obtained from forty scans of five volunteers in four postures (free-standing, holding side supports, holding front supports and with their hands on their shoulders) were used to assess the variability due to posture. Twenty cross-sections from twenty scans of two volunteers holding side supports were used to assess the variability due to positioning. The variability due to posture was less than 4mm at each cross-section for all volunteers. Variability due to sway ranged from 0-3.5mm while that due to breathing ranged from 0-3mm for both volunteers. Holding side supports was the best posture. Taking the four shots within 10 seconds was optimal. As major torso features that are indicative of scoliosis are larger than 4mm in size, the system could be used in obtaining complete torso images used in assessing and managing scoliosis.

Image reduction pipeline for the detection of variable sources in highly crowded fields

NASA Astrophysics Data System (ADS)

Gössl, C. A.; Riffeser, A.

2002-01-01

We present a reduction pipeline for CCD (charge-coupled device) images which was built to search for variable sources in highly crowded fields like the M 31 bulge and to handle extensive databases due to large time series. We describe all steps of the standard reduction in detail with emphasis on the realisation of per pixel error propagation: Bias correction, treatment of bad pixels, flatfielding, and filtering of cosmic rays. The problems of conservation of PSF (point spread function) and error propagation in our image alignment procedure as well as the detection algorithm for variable sources are discussed: we build difference images via image convolution with a technique called OIS (optimal image subtraction, Alard & Lupton \\cite{1998ApJ...503..325A}), proceed with an automatic detection of variable sources in noise dominated images and finally apply a PSF-fitting, relative photometry to the sources found. For the WeCAPP project (Riffeser et al. \\cite{2001A&A...0000..00R}) we achieve 3sigma detections for variable sources with an apparent brightness of e.g. m = 24.9;mag at their minimum and a variation of Delta m = 2.4;mag (or m = 21.9;mag brightness minimum and a variation of Delta m = 0.6;mag) on a background signal of 18.1;mag/arcsec2 based on a 500;s exposure with 1.5;arcsec seeing at a 1.2;m telescope. The complete per pixel error propagation allows us to give accurate errors for each measurement.

Abnormally high formation pressures, Potwar Plateau, Pakistan

USGS Publications Warehouse

Law, B.E.; Shah, S.H.A.; Malik, M.A.

1998-01-01

Abnormally high formation pressures in the Potwar Plateau of north-central Pakistan are major obstacles to oil and gas exploration. Severe drilling problems associated with high pressures have, in some cases, prevented adequate evaluation of reservoirs and significantly increased drilling costs. Previous investigations of abnormal pressure in the Potwar Plateau have only identified abnormal pressures in Neogene rocks. We have identified two distinct pressure regimes in this Himalayan foreland fold and thrust belt basin: one in Neogene rocks and another in pre-Neogene rocks. Pore pressures in Neogene rocks are as high as lithostatic and are interpreted to be due to tectonic compression and compaction disequilibrium associated with high rates of sedimentation. Pore pressure gradients in pre-Neogene rocks are generally less than those in Neogene rocks, commonly ranging from 0.5 to 0.7 psi/ft (11.3 to 15.8 kPa/m) and are most likely due to a combination of tectonic compression and hydrocarbon generation. The top of abnormally high pressure is highly variable and doesn't appear to be related to any specific lithologic seal. Consequently, attempts to predict the depth to the top of overpressure prior to drilling are precluded.

Acid neutralization capacity measurements in surface and ground waters in the Upper River Severn, Plynlimon: from hydrograph splitting to water flow pathways

NASA Astrophysics Data System (ADS)

Neal, C.; Hill, T.; Hill, S.; Reynolds, B.

Acid Neutralization Capacity (ANC) data for ephemeral stream and shallow groundwater for the catchments of the upper River Severn show a highly heterogeneous system of within-catchment water flow pathways and chemical weathering on scales of less than 100m. Ephemeral streams draining permeable soils seem to be supplied mainly from shallow groundwater sources. For these streams, large systematic differences in pH and alkalinity occur due to the variability of the groundwater sources and variability in water residence times. However, the variability cannot be gauged on the basis of broad based physical information collected in the field as geology, catchment gradients and forest structure are very similar. In contrast, ephemeral streams draining impermeable soils are of more uniform chemistry as surface runoff is mainly supplied from the soil zone. Groundwater ANC varies considerably over space and time. In general, the groundwaters have higher ANCs than the ephemeral streams. This is due to increased chemical weathering from the inorganic materials in the lower soils and groundwater areas and possibly longer residence times. However, during the winter months the groundwater ANCs tend to be at their lowest due to additional event driven acidic soil water contributions and intermediate groundwater residence times. The results indicate the inappropriateness of a blanket approach to classifying stream vulnerability to acidification simply on the basis of soil sensitivity. However, the results may well indicate good news for the environmental management of acidic and acid sensitive systems. For example, they clearly indicate a large potential supply of weathering components within the groundwater zone to reduce or mitigate the acidifying effects of land use change and acidic deposition without the environmental needs for Aiming. Furthermore, the high variability of ephemeral stream runoff means that certain areas of catchments where there are specific problems associated with acidification can be identified for focused remediation work for the situation where liming is required. The case for focused field campaigns and caution against over reliance on blanket modelling approaches is suggested. The results negate the conventional generalizations within hydrology of how water moves through catchments to generate streamflow events (from Hortonian overland flow to catchment contributing areas).

Very fast optical flaring from a possible new Galactic magnetar.

PubMed

Stefanescu, A; Kanbach, G; Słowikowska, A; Greiner, J; McBreen, S; Sala, G

2008-09-25

Highly luminous rapid flares are characteristic of processes around compact objects like white dwarfs, neutron stars and black holes. In the high-energy regime of X-rays and gamma-rays, outbursts with variabilities on timescales of seconds or less are routinely observed, for example in gamma-ray bursts or soft gamma-ray repeaters. At optical wavelengths, flaring activity on such timescales has not been observed, other than from the prompt phase of one exceptional gamma-ray burst. This is mostly due to the fact that outbursts with strong, fast flaring are usually discovered in the high-energy regime; most optical follow-up observations of such transients use instruments with integration times exceeding tens of seconds, which are therefore unable to resolve fast variability. Here we show the observation of extremely bright and rapid optical flaring in the Galactic transient SWIFT J195509.6+261406. Our optical light curves are phenomenologically similar to high-energy light curves of soft gamma-ray repeaters and anomalous X-ray pulsars, which are thought to be neutron stars with extremely high magnetic fields (magnetars). This suggests that similar processes are in operation, but with strong emission in the optical, unlike in the case of other known magnetars.

High Pressure and Temperature Core Formation as an Alternative to the "Late Veneer" Hypothesis

NASA Technical Reports Server (NTRS)

Righter, Kevin; Pando, K.; Humayun, M.; Danielson, L.

2011-01-01

The highly siderophile elements (HSE; Re, Au and the Platinum Group Elements - Pd Pt, Rh, Ru, Ir, Os) are commonly utilized to constrain accretion processes in terrestrial differentiated bodies due to their affinity for FeNi metal [1]. These eight elements exhibit highly siderophile behavior, but nonetheless have highly diverse metal-silicate partition coefficients [2]. Therefore the near chondritic relative concentrations of HSEs in the terrestrial and lunar mantles, as well as some other bodies, are attributed to late accretion rather than core formation [1]. Evaluation of competing theories, such as high pressure metal-silicate partitioning or magma ocean hypotheses has been hindered by a lack of relevant partitioning data for this group of eight elements. In particular, systematic studies isolating the effect of one variable (e.g. temperature or melt compositions) are lacking. Here we undertake new experiments on all eight elements, using Fe metal and FeO-bearing silicate melts at fixed pressure, but variable temperatures. These experiments, as well as some additional planned experiments should allow partition coefficients to be more accurately calculated or estimated at the PT conditions and compositions at which core formation is thought to have occurred.

[Congenital pseudohypoaldosteronism: apropos of 6 cases].

PubMed

Cessans, C; Berthier, M; Bonneau, D; Millet, C; Mettey, R

1989-01-01

Pseudohypoaldosteronism is a congenital disorder, with an as yet unclear pathophysiology, mode of inheritance and frequency. We have recently diagnosed 6 cases in a relatively short period of time, which suggests that the frequency of the disease may be underestimated. This may be due to a high variability in the clinical expression and to the existence of asymptomatic forms. Autosomal dominant and autosomal recessive modes of inheritance have been reported which probably correspond to different underlying mechanisms.

Bowhead and gray whale migration model description. Interim report No. 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1985-03-22

Migration models for bowhead and gray whales in Alaskan waters were conceptualized, programmed, calibrated, and tested against observations. These verification tests do not supply irrefutable evidence that the model reproduces an average migratory pattern for either species. This is due in part to the high degree of interannual variability that normally occurs in Arctic and sub-Arctic environments. Furthermore, the model structure is flexible enough to allow changes to be readily implemented.

Good Days, Bad Days: Wind as a Driver of Foraging Success in a Flightless Seabird, the Southern Rockhopper Penguin

PubMed Central

Dehnhard, Nina; Ludynia, Katrin; Poisbleau, Maud; Demongin, Laurent; Quillfeldt, Petra

2013-01-01

Due to their restricted foraging range, flightless seabirds are ideal models to study the short-term variability in foraging success in response to environmentally driven food availability. Wind can be a driver of upwelling and food abundance in marine ecosystems such as the Southern Ocean, where wind regime changes due to global warming may have important ecological consequences. Southern rockhopper penguins (Eudyptes chrysocome) have undergone a dramatic population decline in the past decades, potentially due to changing environmental conditions. We used a weighbridge system to record daily foraging mass gain (the difference in mean mass of adults leaving the colony in the morning and returning to the colony in the evening) of adult penguins during the chick rearing in two breeding seasons. We related the day-to-day variability in foraging mass gain to ocean wind conditions (wind direction and wind speed) and tested for a relationship between wind speed and sea surface temperature anomaly (SSTA). Foraging mass gain was highly variable among days, but did not differ between breeding seasons, chick rearing stages (guard and crèche) and sexes. It was strongly correlated between males and females, indicating synchronous changes among days. There was a significant interaction of wind direction and wind speed on daily foraging mass gain. Foraging mass gain was highest under moderate to strong winds from westerly directions and under weak winds from easterly directions, while decreasing under stronger easterly winds and storm conditions. Ocean wind speed showed a negative correlation with daily SSTA, suggesting that winds particularly from westerly directions might enhance upwelling and consequently the prey availability in the penguins' foraging areas. Our data emphasize the importance of small-scale, wind-induced patterns in prey availability on foraging success, a widely neglected aspect in seabird foraging studies, which might become more important with increasing changes in climatic variability. PMID:24236139

Highly specialized microbial diversity in hyper-arid polar desert

PubMed Central

Pointing, Stephen B.; Chan, Yuki; Lacap, Donnabella C.; Lau, Maggie C. Y.; Jurgens, Joel A.; Farrell, Roberta L.

2009-01-01

The McMurdo Dry Valleys in Antarctica are a cold hyperarid polar desert that present extreme challenges to life. Here, we report a culture-independent survey of multidomain microbial biodiversity in McKelvey Valley, a pristine example of the coldest desert on Earth. We demonstrate that life has adapted to form highly-specialized communities in distinct lithic niches occurring concomitantly within this terrain. Endoliths and chasmoliths in sandstone displayed greatest diversity, whereas soil was relatively depauperate and lacked a significant photoautotrophic component, apart from isolated islands of hypolithic cyanobacterial colonization on quartz rocks in soil contact. Communities supported previously unreported polar bacteria and fungi, but archaea were absent from all niches. Lithic community structure did not vary significantly on a landscape scale and stochastic moisture input due to snowmelt resulted in increases in colonization frequency without significantly affecting diversity. The findings show that biodiversity near the cold-arid limit for life is more complex than previously appreciated, but communities lack variability probably due to the high selective pressures of this extreme environment. PMID:19850879

Characterizing Temperature Variability and Associated Large Scale Meteorological Patterns Across South America

NASA Astrophysics Data System (ADS)

Detzer, J.; Loikith, P. C.; Mechoso, C. R.; Barkhordarian, A.; Lee, H.

2017-12-01

South America's climate varies considerably owing to its large geographic range and diverse topographical features. Spanning the tropics to the mid-latitudes and from high peaks to tropical rainforest, the continent experiences an array of climate and weather patterns. Due to this considerable spatial extent, assessing temperature variability at the continent scale is particularly challenging. It is well documented in the literature that temperatures have been increasing across portions of South America in recent decades, and while there have been many studies that have focused on precipitation variability and change, temperature has received less scientific attention. Therefore, a more thorough understanding of the drivers of temperature variability is critical for interpreting future change. First, k-means cluster analysis is used to identify four primary modes of temperature variability across the continent, stratified by season. Next, composites of large scale meteorological patterns (LSMPs) are calculated for months assigned to each cluster. Initial results suggest that LSMPs, defined using meteorological variables such as sea level pressure (SLP), geopotential height, and wind, are able to identify synoptic scale mechanisms important for driving temperature variability at the monthly scale. Some LSMPs indicate a relationship with known recurrent modes of climate variability. For example, composites of geopotential height suggest that the Southern Annular Mode is an important, but not necessarily dominant, component of temperature variability over southern South America. This work will be extended to assess the drivers of temperature extremes across South America.

A Search for Photometric Variability in the Young T3.5 Planetary-mass Companion GU Psc b

NASA Astrophysics Data System (ADS)

Naud, Marie-Eve; Artigau, Étienne; Rowe, Jason F.; Doyon, René; Malo, Lison; Albert, Loïc; Gagné, Jonathan; Bouchard, Sandie

2017-10-01

We present a photometric J-band variability study of GU Psc b, a T3.5 co-moving planetary-mass companion (9-13 {M}{Jup}) to a young (˜150 Myr) M3 member of the AB Doradus Moving Group. The large separation between GU Psc b and its host star (42″) provides a rare opportunity to study the photometric variability of a planetary-mass companion. The study presented here is based on observations obtained from 2013 to 2014 over three nights with durations of 5-6 hr each with the WIRCam imager at Canada-France-Hawaii Telescope. Photometric variability with a peak-to-peak amplitude of 4 ± 1% at a timescale of ˜6 hr was marginally detected on 2014 October 11. No high-significance variability was detected on 2013 December 22 and 2014 October 10. The amplitude and timescale of the variability seen here, as well as its evolving nature, is comparable to what was observed for a variety of field T dwarfs and suggests that mechanisms invoked to explain brown dwarf variability may be applicable to low-gravity objects such as GU Psc b. Rotation-induced photometric variability due to the formation and dissipation of atmospheric features such as clouds is a plausible hypothesis for the tentative variation detected here. Additional photometric measurements, particularly on longer timescales, will be required to confirm and characterize the variability of GU Psc b, determine its periodicity and to potentially measure its rotation period.

Phase dependence of transport-aperture coordination variability reveals control strategy of reach-to-grasp movements.

PubMed

Rand, Miya K; Shimansky, Y P; Hossain, Abul B M I; Stelmach, George E

2010-11-01

Based on an assumption of movement control optimality in reach-to-grasp movements, we have recently developed a mathematical model of transport-aperture coordination (TAC), according to which the hand-target distance is a function of hand velocity and acceleration, aperture magnitude, and aperture velocity and acceleration (Rand et al. in Exp Brain Res 188:263-274, 2008). Reach-to-grasp movements were performed by young adults under four different reaching speeds and two different transport distances. The residual error magnitude of fitting the above model to data across different trials and subjects was minimal for the aperture-closure phase, but relatively much greater for the aperture-opening phase, indicating considerable difference in TAC variability between those phases. This study's goal is to identify the main reasons for that difference and obtain insights into the control strategy of reach-to-grasp movements. TAC variability within the aperture-opening phase of a single trial was found minimal, indicating that TAC variability between trials was not due to execution noise, but rather a result of inter-trial and inter-subject variability of motor plan. At the same time, the dependence of the extent of trial-to-trial variability of TAC in that phase on the speed of hand transport was sharply inconsistent with the concept of speed-accuracy trade-off: the lower the speed, the larger the variability. Conversely, the dependence of the extent of TAC variability in the aperture-closure phase on hand transport speed was consistent with that concept. Taking into account recent evidence that the cost of neural information processing is substantial for movement planning, the dependence of TAC variability in the aperture-opening phase on task performance conditions suggests that it is not the movement time that the CNS saves in that phase, but the cost of neuro-computational resources and metabolic energy required for TAC regulation in that phase. Thus, the CNS performs a trade-off between that cost and TAC regulation accuracy. It is further discussed that such trade-off is possible because, due to a special control law that governs optimal switching from aperture opening to aperture closure, the inter-trial variability of the end of aperture opening does not affect the high accuracy of TAC regulation in the subsequent aperture-closure phase.

The risk-adjusted vision beyond casemix (DRG) funding in Australia. International lessons in high complexity and capitation.

PubMed

Antioch, Kathryn M; Walsh, Michael K

2004-06-01

Hospitals throughout the world using funding based on diagnosis-related groups (DRG) have incurred substantial budgetary deficits, despite high efficiency. We identify the limitations of DRG funding that lack risk (severity) adjustment for State-wide referral services. Methods to risk adjust DRGs are instructive. The average price in casemix funding in the Australian State of Victoria is policy based, not benchmarked. Average cost weights are too low for high-complexity DRGs relating to State-wide referral services such as heart and lung transplantation and trauma. Risk-adjusted specified grants (RASG) are required for five high-complexity respiratory, cardiology and stroke DRGs incurring annual deficits of $3.6 million due to high casemix complexity and government under-funding despite high efficiency. Five stepwise linear regressions for each DRG excluded non-significant variables and assessed heteroskedasticity and multicollinearlity. Cost per patient was the dependent variable. Significant independent variables were age, length-of-stay outliers, number of disease types, diagnoses, procedures and emergency status. Diagnosis and procedure severity markers were identified. The methodology and the work of the State-wide Risk Adjustment Working Group can facilitate risk adjustment of DRGs State-wide and for Treasury negotiations for expenditure growth. The Alfred Hospital previously negotiated RASG of $14 million over 5 years for three trauma and chronic DRGs. Some chronic diseases require risk-adjusted capitation funding models for Australian Health Maintenance Organizations as an alternative to casemix funding. The use of Diagnostic Cost Groups can facilitate State and Federal government reform via new population-based risk adjusted funding models that measure health need.

Nitrate, Nitrite, and Ammonium Variability in Drinking Water Distribution Systems.

PubMed

Schullehner, Jörg; Stayner, Leslie; Hansen, Birgitte

2017-03-09

Accurate assessments of exposure to nitrate in drinking water is a crucial part of epidemiological studies investigating long-term adverse human health effects. However, since drinking water nitrate measurements are usually collected for regulatory purposes, assumptions on (1) the intra-distribution system variability and (2) short-term (seasonal) concentration variability have to be made. We assess concentration variability in the distribution system of nitrate, nitrite, and ammonium, and seasonal variability in all Danish public waterworks from 2007 to 2016. Nitrate concentrations at the exit of the waterworks are highly correlated with nitrate concentrations within the distribution net or at the consumers' taps, while nitrite and ammonium concentrations are generally lower within the net compared with the exit of the waterworks due to nitrification. However, nitrification of nitrite and ammonium in the distribution systems only results in a relatively small increase in nitrate concentrations. No seasonal variation for nitrate, nitrite, or ammonium was observed. We conclude that nitrate measurements taken at the exit of the waterworks are suitable to calculate exposures for all consumers connected to that waterworks and that sampling frequencies in the national monitoring programme are sufficient to describe temporal variations in longitudinal studies.

Increased QT interval variability index in acute alcohol withdrawal.

PubMed

Bär, Karl-Jürgen; Boettger, Michael Karl; Koschke, Mandy; Boettger, Silke; Grotelüschen, Marei; Voss, Andreas; Yeragani, Vikram K

2007-07-10

Acute alcohol withdrawal is associated with increased cardiovascular mortality, most likely due to cardiac arrhythmias. As the QT interval reflects the most critical phase for the generation of reentry and thus for arrhythmia, we examined QT variability in patients suffering from acute alcohol withdrawal. High resolution electrocardiographic recordings were performed in 18 male unmedicated patients suffering from acute alcohol withdrawal, 18 matched controls and 15 abstained alcoholics. From these, parameters of beat-to-beat heart rate and QT variability such as approximate entropy and QT variability index (QTvi) were calculated. Measures were correlated with the severity of withdrawal symptoms and with serum electrolyte concentrations. Heart rate and QTvi were significantly increased in acute alcohol withdrawal. Abstained alcoholics did not significantly differ from controls. While QTvi correlated with the severity of alcohol withdrawal symptoms, the mean QT interval duration showed an inverse relationship with serum potassium concentrations. Our data indicate increased QT variability and thus increased repolarization lability in acute alcohol withdrawal. This might add to the elevated risk for serious cardiac arrhythmias. In part, these changes might be related to increased cardiac sympathetic activity or low potassium, thus suggesting the latter as possible targets for adjuvant pharmacological therapy during withdrawal.

Robust optimization modelling with applications to industry and environmental problems

NASA Astrophysics Data System (ADS)

Chaerani, Diah; Dewanto, Stanley P.; Lesmana, Eman

2017-10-01

Robust Optimization (RO) modeling is one of the existing methodology for handling data uncertainty in optimization problem. The main challenge in this RO methodology is how and when we can reformulate the robust counterpart of uncertain problems as a computationally tractable optimization problem or at least approximate the robust counterpart by a tractable problem. Due to its definition the robust counterpart highly depends on how we choose the uncertainty set. As a consequence we can meet this challenge only if this set is chosen in a suitable way. The development on RO grows fast, since 2004, a new approach of RO called Adjustable Robust Optimization (ARO) is introduced to handle uncertain problems when the decision variables must be decided as a ”wait and see” decision variables. Different than the classic Robust Optimization (RO) that models decision variables as ”here and now”. In ARO, the uncertain problems can be considered as a multistage decision problem, thus decision variables involved are now become the wait and see decision variables. In this paper we present the applications of both RO and ARO. We present briefly all results to strengthen the importance of RO and ARO in many real life problems.

Nitrate, Nitrite, and Ammonium Variability in Drinking Water Distribution Systems

PubMed Central

Schullehner, Jörg; Stayner, Leslie; Hansen, Birgitte

2017-01-01

Accurate assessments of exposure to nitrate in drinking water is a crucial part of epidemiological studies investigating long-term adverse human health effects. However, since drinking water nitrate measurements are usually collected for regulatory purposes, assumptions on (1) the intra-distribution system variability and (2) short-term (seasonal) concentration variability have to be made. We assess concentration variability in the distribution system of nitrate, nitrite, and ammonium, and seasonal variability in all Danish public waterworks from 2007 to 2016. Nitrate concentrations at the exit of the waterworks are highly correlated with nitrate concentrations within the distribution net or at the consumers’ taps, while nitrite and ammonium concentrations are generally lower within the net compared with the exit of the waterworks due to nitrification. However, nitrification of nitrite and ammonium in the distribution systems only results in a relatively small increase in nitrate concentrations. No seasonal variation for nitrate, nitrite, or ammonium was observed. We conclude that nitrate measurements taken at the exit of the waterworks are suitable to calculate exposures for all consumers connected to that waterworks and that sampling frequencies in the national monitoring programme are sufficient to describe temporal variations in longitudinal studies. PMID:28282914

Downscaling scheme to drive soil-vegetation-atmosphere transfer models

NASA Astrophysics Data System (ADS)

Schomburg, Annika; Venema, Victor; Lindau, Ralf; Ament, Felix; Simmer, Clemens

2010-05-01

The earth's surface is characterized by heterogeneity at a broad range of scales. Weather forecast models and climate models are not able to resolve this heterogeneity at the smaller scales. Many processes in the soil or at the surface, however, are highly nonlinear. This holds, for example, for evaporation processes, where stomata or aerodynamic resistances are nonlinear functions of the local micro-climate. Other examples are threshold dependent processes, e.g., the generation of runoff or the melting of snow. It has been shown that using averaged parameters in the computation of these processes leads to errors and especially biases, due to the involved nonlinearities. Thus it is necessary to account for the sub-grid scale surface heterogeneities in atmospheric modeling. One approach to take the variability of the earth's surface into account is the mosaic approach. Here the soil-vegetation-atmosphere transfer (SVAT) model is run on an explicit higher resolution than the atmospheric part of a coupled model, which is feasible due to generally lower computational costs of a SVAT model compared to the atmospheric part. The question arises how to deal with the scale differences at the interface between the two resolutions. Usually the assumption of a homogeneous forcing for all sub-pixels is made. However, over a heterogeneous surface, usually the boundary layer is also heterogeneous. Thus, by assuming a constant atmospheric forcing again biases in the turbulent heat fluxes may occur due to neglected atmospheric forcing variability. Therefore we have developed and tested a downscaling scheme to disaggregate the atmospheric variables of the lower atmosphere that are used as input to force a SVAT model. Our downscaling scheme consists of three steps: 1) a bi-quadratic spline interpolation of the coarse-resolution field; 2) a "deterministic" part, where relationships between surface and near-surface variables are exploited; and 3) a noise-generation step, in which the still missing, not explained, variance is added as noise. The scheme has been developed and tested based on high-resolution (400 m) model output of the weather forecast (and regional climate) COSMO model. Downscaling steps 1 and 2 reduce the error made by the homogeneous assumption considerably, whereas the third step leads to close agreement of the sub-grid scale variance with the reference. This is, however, achieved at the cost of higher root mean square errors. Thus, before applying the downscaling system to atmospheric data a decision should be made whether the lowest possible errors (apply only downscaling step 1 and 2) or a most realistic sub-grid scale variability (apply also step 3) is desired. This downscaling scheme is currently being implemented into the COSMO model, where it will be used in combination with the mosaic approach. However, this downscaling scheme can also be applied to drive stand-alone SVAT models or hydrological models, which usually also need high-resolution atmospheric forcing data.

Addressing variability in the acoustic startle reflex for accurate gap detection assessment.

PubMed

Longenecker, Ryan J; Kristaponyte, Inga; Nelson, Gregg L; Young, Jesse W; Galazyuk, Alexander V

2018-06-01

The acoustic startle reflex (ASR) is subject to substantial variability. This inherent variability consequently shapes the conclusions drawn from gap-induced prepulse inhibition of the acoustic startle reflex (GPIAS) assessments. Recent studies have cast doubt as to the efficacy of this methodology as it pertains to tinnitus assessment, partially, due to variability in and between data sets. The goal of this study was to examine the variance associated with several common data collection variables and data analyses with the aim to improve GPIAS reliability. To study this the GPIAS tests were conducted in adult male and female CBA/CaJ mice. Factors such as inter-trial interval, circadian rhythm, sex differences, and sensory adaptation were each evaluated. We then examined various data analysis factors which influence GPIAS assessment. Gap-induced facilitation, data processing options, and assessments of tinnitus were studied. We found that the startle reflex is highly variable in CBA/CaJ mice, but this can be minimized by certain data collection factors. We also found that careful consideration of temporal fluctuations of the ASR and controlling for facilitation can lead to more accurate GPIAS results. This study provides a guide for reducing variance in the GPIAS methodology - thereby improving the diagnostic power of the test. Copyright © 2018 Elsevier B.V. All rights reserved.

Influence of lifestyle and genetic variants in the aldo-keto reductase 1C3 rs12529 polymorphism in high-risk prostate cancer detection variability assessed between US and New Zealand cohorts

PubMed Central

Ambs, Stefan; Tang, Wei; Zhu, Shuotun; Dorsey, Tiffany H.; Goudie, Megan; Masters, Jonathan G.; Ferguson, Lynnette R.

2018-01-01

Introduction The prostate-specific antigen (PSA) based prostate cancer (PC) screening is currently being debated. The current assessment is to understand the variability of detecting high-risk PC in a NZ cohort in comparison to a US cohort with better PSA screening facilities. Aldo-keto reductase 1C3 (AKR1C3) is known for multiple functions with a potential to regulate subsequent PSA levels. Therefore, we wish to understand the influence of tobacco smoking and the AKR1C3 rs12529 gene polymorphism in this variability. Method NZ cohort (n = 376) consisted of 94% Caucasians while the US cohort consisted of African Americans (AA), n = 202, and European Americans (EA), n = 232. PSA level, PC grade and stage at diagnosis were collected from hospital databases for assigning high-risk PC status. Tobacco smoking status and the AKR1C3 rs12529 SNP genotype were considered as confounding variables. Variation of the cumulative % high-risk PC (outcome variable) with increasing PSA intervals (exposure factor) was compared between the cohorts using the Kolmogorov-Smirnov test. Comparisons were carried out with and without stratifications made using confounding variables. Results NZ cohort has been diagnosed at a significantly higher mean age (66.67± (8.08) y) compared to both AA (62.65±8.17y) and EA (64.83+8.56y); median PSA (NZ 8.90ng/ml compared to AA 6.86ng/ml and EA 5.80ng/ml); and Gleason sum (NZ (7) compared EA (6)) (p<0.05). The cumulative % high-risk PC detection shows NZ cohort with a significantly lower diagnosis rates at PSA levels between >6 - <10ng/ml compared to both US groups (p<0.05). These were further compounded significantly by smoking status and genetics. Conclusions High-risk PCs recorded at higher PSA levels in NZ could be due to factors including lower levels of PSA screening and subsequent specialist referrals for biopsies. These consequences could be pronounced among NZ ever smokers carrying the AKR1C3 rs12529 G alleles making them a group that requires increased PSA screening attention. PMID:29920533

[Prostitutes of the east sector of Santiago: characteristics and pathology of sexual transmission].

PubMed

Medina, R; Mella, L; Espoz, H; Medina, E; Cumsille, F

1989-09-01

We studied the frequency of venereal disease in 329 prostitutes working at massage parlours in Santiago. The mean age was 24 years and half of them had high school or university studies. In spite of frequent sexual contacts averaging 2.8 per day, the prevalence of significant venereal disease was not high in this group. Notably, AIDS infection was not detected. Vaginitis due to Trichomonas or Candida infection was the commonest problem and this was half as frequent among gum preservative users. Marital condition, age, obstetrical history and other variables were not related to genital infection.

Sources and pathways of the upscale effects on the Southern Hemisphere jet in MPAS-CAM4 variable-resolution simulations

DOE PAGES

Sakaguchi, Koichi; Lu, Jian; Leung, L. Ruby; ...

2016-10-22

Impacts of regional grid refinement on large-scale circulations (“upscale effects”) were detected in a previous study that used the Model for Prediction Across Scales-Atmosphere coupled to the physics parameterizations of the Community Atmosphere Model version 4. The strongest upscale effect was identified in the Southern Hemisphere jet during austral winter. This study examines the detailed underlying processes by comparing two simulations at quasi-uniform resolutions of 30 and 120 km to three variable-resolution simulations in which the horizontal grids are regionally refined to 30 km in North America, South America, or Asia from 120 km elsewhere. In all the variable-resolution simulations,more » precipitation increases in convective areas inside the high-resolution domains, as in the reference quasi-uniform high-resolution simulation. With grid refinement encompassing the tropical Americas, the increased condensational heating expands the local divergent circulations (Hadley cell) meridionally such that their descending branch is shifted poleward, which also pushes the baroclinically unstable regions, momentum flux convergence, and the eddy-driven jet poleward. This teleconnection pathway is not found in the reference high-resolution simulation due to a strong resolution sensitivity of cloud radiative forcing that dominates the aforementioned teleconnection signals. The regional refinement over Asia enhances Rossby wave sources and strengthens the upper level southerly flow, both facilitating the cross-equatorial propagation of stationary waves. Evidence indicates that this teleconnection pathway is also found in the reference high-resolution simulation. Lastly, the result underlines the intricate diagnoses needed to understand the upscale effects in global variable-resolution simulations, with implications for science investigations using the computationally efficient modeling framework.« less

Non-Gaussian Multi-resolution Modeling of Magnetosphere-Ionosphere Coupling Processes

NASA Astrophysics Data System (ADS)

Fan, M.; Paul, D.; Lee, T. C. M.; Matsuo, T.

2016-12-01

The most dynamic coupling between the magnetosphere and ionosphere occurs in the Earth's polar atmosphere. Our objective is to model scale-dependent stochastic characteristics of high-latitude ionospheric electric fields that originate from solar wind magnetosphere-ionosphere interactions. The Earth's high-latitude ionospheric electric field exhibits considerable variability, with increasing non-Gaussian characteristics at decreasing spatio-temporal scales. Accurately representing the underlying stochastic physical process through random field modeling is crucial not only for scientific understanding of the energy, momentum and mass exchanges between the Earth's magnetosphere and ionosphere, but also for modern technological systems including telecommunication, navigation, positioning and satellite tracking. While a lot of efforts have been made to characterize the large-scale variability of the electric field in the context of Gaussian processes, no attempt has been made so far to model the small-scale non-Gaussian stochastic process observed in the high-latitude ionosphere. We construct a novel random field model using spherical needlets as building blocks. The double localization of spherical needlets in both spatial and frequency domains enables the model to capture the non-Gaussian and multi-resolutional characteristics of the small-scale variability. The estimation procedure is computationally feasible due to the utilization of an adaptive Gibbs sampler. We apply the proposed methodology to the computational simulation output from the Lyon-Fedder-Mobarry (LFM) global magnetohydrodynamics (MHD) magnetosphere model. Our non-Gaussian multi-resolution model results in characterizing significantly more energy associated with the small-scale ionospheric electric field variability in comparison to Gaussian models. By accurately representing unaccounted-for additional energy and momentum sources to the Earth's upper atmosphere, our novel random field modeling approach will provide a viable remedy to the current numerical models' systematic biases resulting from the underestimation of high-latitude energy and momentum sources.

Drivers of River Water Temperature Space-time Variability in Northeast Greenland

NASA Astrophysics Data System (ADS)

Hannah, D. M.; Docherty, C.; Milner, A.

2015-12-01

Water temperature plays an important role in stream ecosystem functioning; however, water temperature dynamics in high Arctic environments have received relatively little attention. Given that global climate is predicted to change most at high latitudes, it is vital we broaden our knowledge of space-time variability in Arctic river temperature to understand controlling processes and potential consequences of climate change. To address this gap, our research aims: (1) to characterise seasonal and diel patterns of variability over three summer and two winter seasons with contrasting hydrometeorological conditions, (2) to unravel the key drivers influencing thermal regimes and (3) to place these results in the context of other snow/ glacier-melt dominated environments. Fieldwork was undertaken in July-September 2013, 2014 and 2015 close to the Zackenberg Research Station in Northeast Greenland - an area of continuous permafrost with a mean July air temperature of 6 °C. Five streams were chosen that drain different water source contributions (glacier melt, snow melt, groundwater). Data were collected at 30 minute intervals using micro-dataloggers. Air temperature data were collected within 7km by the Greenland Survey. Weather conditions were highly variable between field campaigns, with 2013 experiencing below average, and 2014 and 2015 above average, snowfall. Summer water temperatures appear to be high in comparison to some Arctic streams in Alaska and in Svalbard. Winter snowfall extent decreases stream water temperature; and water temperature increases with atmospheric exposure time (distance from source) - illustrating the intertwined controls of water and heat fluxes. These Greenland streams are most strongly influenced by snowmelt, but groundwater contributions could increase with a changing climate due to increased active layer thickness, which may result in increased river temperature with implications for aquatic biodiversity and ecosystem functioning.

A New Formulation for Fresh Snow Density over Antarctica for the regional climate model Modèle Atmosphérique Régionale (MAR).

NASA Astrophysics Data System (ADS)

Tedesco, M.; Datta, R.; Fettweis, X.; Agosta, C.

2015-12-01

Surface-layer snow density is important to processes contributing to surface mass balance, but is highly variable over Antarctica due to a wide range of near-surface climate conditions over the continent. Formulations for fresh snow density have typically either used fixed values or been modeled empirically using field data that is limited to specific seasons or regions. There is also currently limited work exploring how the sensitivity to fresh snow density in regional climate models varies with resolution. Here, we present a new formulation compiled from (a) over 1600 distinct density profiles from multiple sources across Antarctica and (b) near-surface variables from the regional climate model Modèle Atmosphérique Régionale (MAR). Observed values represent coastal areas as well as the plateau, in both West and East Antarctica (although East Antarctica is dominant). However, no measurements are included from the Antarctic Peninsula, which is both highly topographically variable and extends to lower latitudes than the remainder of the continent. In order to assess the applicability of this fresh snow density formulation to the Antarctic Peninsula at high resolutions, a version of MAR is run for several years both at low-resolution at the continental scale and at a high resolution for the Antarctic Peninsula alone. This setup is run both with and without the new fresh density formulation to quantify the sensitivity of the energy balance and SMB components to fresh snow density. Outputs are compared with near-surface atmospheric variables available from AWS stations (provided by the University of Wisconsin Madison) as well as net accumulation values from the SAMBA database (provided from the Laboratoire de Glaciologie et Géophysique de l'Environnement).

Pricing index-based catastrophe bonds: Part 2: Object-oriented design issues and sensitivity analysis

NASA Astrophysics Data System (ADS)

Unger, André J. A.

2010-02-01

This work is the second installment in a two-part series, and focuses on object-oriented programming methods to implement an augmented-state variable approach to aggregate the PCS index and introduce the Bermudan-style call feature into the proposed CAT bond model. The PCS index is aggregated quarterly using a discrete Asian running-sum formulation. The resulting aggregate PCS index augmented-state variable is used to specify the payoff (principle) on the CAT bond based on reinsurance layers. The purpose of the Bermudan-style call option is to allow the reinsurer to minimize their interest rate risk exposure on making fixed coupon payments under prevailing interest rates. A sensitivity analysis is performed to determine the impact of uncertainty in the frequency and magnitude of hurricanes on the price of the CAT bond. Results indicate that while the CAT bond is highly sensitive to the natural variability in the frequency of landfalling hurricanes between El Ninõ and non-El Ninõ years, it remains relatively insensitive to uncertainty in the magnitude of damages. In addition, results indicate that the maximum price of the CAT bond is insensitive to whether it is engineered to cover low frequency high magnitude events in a 'high' reinsurance layer relative to high frequency low magnitude events in a 'low' reinsurance layer. Also, while it is possible for the reinsurer to minimize their interest rate risk exposure on the fixed coupon payments, the impact of this risk on the price of the CAT bond appears small relative to the natural variability in the CAT bond price, and consequently catastrophic risk, due to uncertainty in the frequency and magnitude of landfalling hurricanes.

Sources and pathways of the upscale effects on the Southern Hemisphere jet in MPAS-CAM4 variable-resolution simulations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sakaguchi, Koichi; Lu, Jian; Leung, L. Ruby

Impacts of regional grid refinement on large-scale circulations (“upscale effects”) were detected in a previous study that used the Model for Prediction Across Scales-Atmosphere coupled to the physics parameterizations of the Community Atmosphere Model version 4. The strongest upscale effect was identified in the Southern Hemisphere jet during austral winter. This study examines the detailed underlying processes by comparing two simulations at quasi-uniform resolutions of 30 and 120 km to three variable-resolution simulations in which the horizontal grids are regionally refined to 30 km in North America, South America, or Asia from 120 km elsewhere. In all the variable-resolution simulations,more » precipitation increases in convective areas inside the high-resolution domains, as in the reference quasi-uniform high-resolution simulation. With grid refinement encompassing the tropical Americas, the increased condensational heating expands the local divergent circulations (Hadley cell) meridionally such that their descending branch is shifted poleward, which also pushes the baroclinically unstable regions, momentum flux convergence, and the eddy-driven jet poleward. This teleconnection pathway is not found in the reference high-resolution simulation due to a strong resolution sensitivity of cloud radiative forcing that dominates the aforementioned teleconnection signals. The regional refinement over Asia enhances Rossby wave sources and strengthens the upper level southerly flow, both facilitating the cross-equatorial propagation of stationary waves. Evidence indicates that this teleconnection pathway is also found in the reference high-resolution simulation. Lastly, the result underlines the intricate diagnoses needed to understand the upscale effects in global variable-resolution simulations, with implications for science investigations using the computationally efficient modeling framework.« less

Kepler's first view of O-star variability: K2 data of five O stars in Campaign 0 as a proof of concept for O-star asteroseismology

NASA Astrophysics Data System (ADS)

Buysschaert, B.; Aerts, C.; Bloemen, S.; Debosscher, J.; Neiner, C.; Briquet, M.; Vos, J.; Pápics, P. I.; Manick, R.; Schmid, V. S.; Van Winckel, H.; Tkachenko, A.

2015-10-01

We present high-precision photometric light curves of five O-type stars observed with the refurbished Kepler satellite during its Campaign 0. For one of the stars, we also assembled high-resolution ground-based spectroscopy with the HERMES spectrograph attached to the 1.2 m Mercator telescope. The stars EPIC 202060097 (O9.5V) and EPIC 202060098 (O7V) exhibit monoperiodic variability due to rotational modulation with an amplitude of 5.6 and 9.3 mmag and a rotation period of 2.63 and 5.03 d, respectively. EPIC 202060091 (O9V) and EPIC 202060093 (O9V:pe) reveal variability at low frequency but the cause is unclear. EPIC 202060092 (O9V:p) is discovered to be a spectroscopic binary with at least one multiperiodic β Cep-type pulsator whose detected mode frequencies occur in the range [0.11, 6.99] d-1 and have amplitudes between 0.8 and 2.0 mmag. Its pulsation spectrum is shown to be fully compatible with the ones predicted by core-hydrogen burning O-star models. Despite the short duration of some 33 d and the limited data quality with a precision near 100 μmag of these first K2 data, the diversity of possible causes for O-star variability already revealed from campaigns of similar duration by the MOST and CoRoT satellites is confirmed with Kepler. We provide an overview of O-star space photometry and give arguments why future K2 monitoring during Campaigns 11 and 13 at short cadence, accompanied by time-resolved high-precision high-resolution spectroscopy, opens up the possibility of in-depth O-star seismology.

Flight data analysis and further development of variable-conductance heat pipes. [for aircraft control

NASA Technical Reports Server (NTRS)

Enginer, J. E.; Luedke, E. E.; Wanous, D. J.

1976-01-01

Continuing efforts in large gains in heat-pipe performance are reported. It was found that gas-controlled variable-conductance heat pipes can perform reliably for long periods in space and effectively provide temperature stabilization for spacecraft electronics. A solution was formulated that allows the control gas to vent through arterial heat-pipe walls, thus eliminating the problem of arterial failure under load, due to trace impurities of noncondensable gas trapped in an arterial bubble during priming. This solution functions well in zero gravity. Another solution was found that allows priming at a much lower fluid charge. A heat pipe with high capacity, with close temperature control of the heat source and independent of large variations in sink temperature was fabricated.

Gravitational lensing by a smoothly variable surface mass density

NASA Technical Reports Server (NTRS)

Paczynski, Bohdan; Wambsganss, Joachim

1989-01-01

The statistical properties of gravitational lensing due to smooth but nonuniform distributions of matter are considered. It is found that a majority of triple images had a parity characteristic for 'shear-induced' lensing. Almost all cases of triple or multiple imaging were associated with large surface density enhancements, and lensing objects were present between the images. Thus, the observed gravitational lens candidates for which no lensing object has been detected between the images are unlikely to be a result of asymmetric distribution of mass external to the image circle. In a model with smoothly variable surface mass density, moderately and highly amplified images tended to be single rather than multiple. An opposite trend was found in models which had singularities in the surface mass distribution.

tICA-Metadynamics: Accelerating Metadynamics by Using Kinetically Selected Collective Variables.

PubMed

M Sultan, Mohammad; Pande, Vijay S

2017-06-13

Metadynamics is a powerful enhanced molecular dynamics sampling method that accelerates simulations by adding history-dependent multidimensional Gaussians along selective collective variables (CVs). In practice, choosing a small number of slow CVs remains challenging due to the inherent high dimensionality of biophysical systems. Here we show that time-structure based independent component analysis (tICA), a recent advance in Markov state model literature, can be used to identify a set of variationally optimal slow coordinates for use as CVs for Metadynamics. We show that linear and nonlinear tICA-Metadynamics can complement existing MD studies by explicitly sampling the system's slowest modes and can even drive transitions along the slowest modes even when no such transitions are observed in unbiased simulations.

Crowd-Sourced Radio Science at Marshall Space Flight Center

NASA Technical Reports Server (NTRS)

Fry, C. D.; McTernan, J. K.; Suggs, R. M.; Rawlins, L.; Krause, L. H.; Gallagher, D. L.; Adams, M. L.

2018-01-01

August 21, 2017 provided a unique opportunity to investigate the effects of the total solar eclipse on high frequency (HF) radio propagation and ionospheric variability. In Marshall Space Flight Center's partnership with the US Space and Rocket Center (USSRC) and Austin Peay State University (APSU), we engaged citizen scientists and students in an investigation of the effects of an eclipse on the mid-latitude ionosphere. Activities included fieldwork and station-based data collection of HF Amateur Radio frequency bands and VLF radio waves before, during, and after the eclipse to build a continuous record of changing propagation conditions as the moon's shadow marched across the United States. Post-eclipse radio propagation analysis provided insights into ionospheric variability due to the eclipse.

Groundwater Withdrawals under Drought: Reconciling GRACE and Models in the United States High Plains Aquifer

NASA Astrophysics Data System (ADS)

Nie, W.; Zaitchik, B. F.; Kumar, S.; Rodell, M.

2017-12-01

Advanced Land Surface Models (LSM) offer a powerful tool for studying and monitoring hydrological variability. Highly managed systems, however, present a challenge for these models, which typically have simplified or incomplete representations of human water use, if the process is represented at all. GRACE, meanwhile, detects the total change in water storage, including change due to human activities, but does not resolve the source of these changes. Here we examine recent groundwater declines in the US High Plains Aquifer (HPA), a region that is heavily utilized for irrigation and that is also affected by episodic drought. To understand observed decline in groundwater (well observation) and terrestrial water storage (GRACE) during a recent multi-year drought, we modify the Noah-MP LSM to include a groundwater pumping irrigation scheme. To account for seasonal and interannual variability in active irrigated area we apply a monthly time-varying greenness vegetation fraction (GVF) dataset to the model. A set of five experiments were performed to study the impact of irrigation with groundwater withdrawal on the simulated hydrological cycle of the HPA and to assess the importance of time-varying GVF when simulating drought conditions. The results show that including the groundwater pumping irrigation scheme in Noah-MP improves model agreement with GRACE mascon solutions for TWS and well observations of groundwater anomaly in the southern HPA, including Texas and Kansas, and that accounting for time-varying GVF is important for model realism under drought. Results for the HPA in Nebraska are mixed, likely due to misrepresentation of the recharge process. This presentation will highlight the value of the GRACE constraint for model development, present estimates of the relative contribution of climate variability and irrigation to declining TWS in the HPA under drought, and identify opportunities to integrate GRACE-FO with models for water resource monitoring in heavily irrigated regions.

Multi-annual modes in the 20th century temperature variability in reanalyses and CMIP5 models

NASA Astrophysics Data System (ADS)

Järvinen, Heikki; Seitola, Teija; Silén, Johan; Räisänen, Jouni

2016-11-01

A performance expectation is that Earth system models simulate well the climate mean state and the climate variability. To test this expectation, we decompose two 20th century reanalysis data sets and 12 CMIP5 model simulations for the years 1901-2005 of the monthly mean near-surface air temperature using randomised multi-channel singular spectrum analysis (RMSSA). Due to the relatively short time span, we concentrate on the representation of multi-annual variability which the RMSSA method effectively captures as separate and mutually orthogonal spatio-temporal components. This decomposition is a unique way to separate statistically significant quasi-periodic oscillations from one another in high-dimensional data sets.The main results are as follows. First, the total spectra for the two reanalysis data sets are remarkably similar in all timescales, except that the spectral power in ERA-20C is systematically slightly higher than in 20CR. Apart from the slow components related to multi-decadal periodicities, ENSO oscillations with approximately 3.5- and 5-year periods are the most prominent forms of variability in both reanalyses. In 20CR, these are relatively slightly more pronounced than in ERA-20C. Since about the 1970s, the amplitudes of the 3.5- and 5-year oscillations have increased, presumably due to some combination of forced climate change, intrinsic low-frequency climate variability, or change in global observing network. Second, none of the 12 coupled climate models closely reproduce all aspects of the reanalysis spectra, although some models represent many aspects well. For instance, the GFDL-ESM2M model has two nicely separated ENSO periods although they are relatively too prominent as compared with the reanalyses. There is an extensive Supplement and YouTube videos to illustrate the multi-annual variability of the data sets.

Thaw depth spatial and temporal variability at the Limnopolar Lake CALM-S site, Byers Peninsula, Livingston Island, Antarctica.

PubMed

de Pablo, M A; Ramos, M; Molina, A; Prieto, M

2018-02-15

A new Circumpolar Active Layer Monitoring (CALM) site was established in 2009 at the Limnopolar Lake watershed in Byers Peninsula, Livingston Island, Antarctica, to provide a node in the western Antarctic Peninsula, one of the regions that recorded the highest air temperature increase in the planet during the last decades. The first detailed analysis of the temporal and spatial evolution of the thaw depth at the Limnopolar Lake CALM-S site is presented here, after eight years of monitoring. The average values range between 48 and 29cm, decreasing at a ratio of 16cm/decade. The annual thaw depth observations in the 100×100 m CALM grid are variable (Variability Index of 34 to 51%), although both the Variance Coefficient and the Climate Matrix Analysis Residual point to the internal consistency of the data. Those differences could be explained then by the terrain complexity and node-specific variability due to the ground properties. The interannual variability was about 60% during 2009-2012, increasing to 124% due to the presence of snow in 2013, 2015 and 2016. The snow has been proposed here as one of the most important factors controlling the spatial variability of ground thaw depth, since its values correlate with the snow thickness but also with the ground surface temperature and unconfined compression resistance, as measured in 2010. The topography explains the thaw depth spatial distribution pattern, being related to snowmelt water and its accumulation in low-elevation areas (downslope-flow). Patterned grounds and other surface features correlate well with high thaw depth patterns as well. The edaphic factor (E=0.05842m 2 /°C·day; R 2 =0.63) is in agreement with other permafrost environments, since frozen index (F>0.67) and MAAT (<-2°C) denote a continuous permafrost existence in the area. All these characteristics provided the basis for further comparative analyses between others nearby CALM sites. Copyright © 2017 Elsevier B.V. All rights reserved.

Solar and atmospheric forcing on mountain lakes.

PubMed

Luoto, Tomi P; Nevalainen, Liisa

2016-10-01

We investigated the influence of long-term external forcing on aquatic communities in Alpine lakes. Fossil microcrustacean (Cladocera) and macrobenthos (Chironomidae) community variability in four Austrian high-altitude lakes, determined as ultra-sensitive to climate change, were compared against records of air temperature, North Atlantic Oscillation (NAO) and solar forcing over the past ~400years. Summer temperature variability affected both aquatic invertebrate groups in all study sites. The influence of NAO and solar forcing on aquatic invertebrates was also significant in the lakes except in the less transparent lake known to have remained uniformly cold during the past centuries due to summertime snowmelt input. The results suggest that external forcing plays an important role in these pristine ecosystems through their impacts on limnology of the lakes. Not only does the air temperature variability influence the communities but also larger-scale external factors related to atmospheric circulation patterns and solar activity cause long-term changes in high-altitude aquatic ecosystems, through their connections to hydroclimatic conditions and light environment. These findings are important in the assessment of climate change impacts on aquatic ecosystems and in greater understanding of the consequences of external forcing on lake ontogeny. Copyright © 2016 Elsevier B.V. All rights reserved.

Difference Image Analysis of Defocused Observations With CSTAR

NASA Astrophysics Data System (ADS)

Oelkers, Ryan J.; Macri, Lucas M.; Wang, Lifan; Ashley, Michael C. B.; Cui, Xiangqun; Feng, Long-Long; Gong, Xuefei; Lawrence, Jon S.; Qiang, Liu; Luong-Van, Daniel; Pennypacker, Carl R.; Yang, Huigen; Yuan, Xiangyan; York, Donald G.; Zhou, Xu; Zhu, Zhenxi

2015-02-01

The Chinese Small Telescope ARray carried out high-cadence time-series observations of 27 square degrees centered on the South Celestial Pole during the Antarctic winter seasons of 2008-2010. Aperture photometry of the 2008 and 2010 i-band images resulted in the discovery of over 200 variable stars. Yearly servicing left the array defocused for the 2009 winter season, during which the system also suffered from intermittent frosting and power failures. Despite these technical issues, nearly 800,000 useful images were obtained using g, r, and clear filters. We developed a combination of difference imaging and aperture photometry to compensate for the highly crowded, blended, and defocused frames. We present details of this approach, which may be useful for the analysis of time-series data from other small-aperture telescopes regardless of their image quality. Using this approach, we were able to recover 68 previously known variables and detected variability in 37 additional objects. We also have determined the observing statistics for Dome A during the 2009 winter season; we find the extinction due to clouds to be less than 0.1 and 0.4 mag for 40% and 63% of the dark time, respectively.

Yield variability prediction by remote sensing sensors with different spatial resolution

NASA Astrophysics Data System (ADS)

Kumhálová, Jitka; Matějková, Štěpánka

2017-04-01

Currently, remote sensing sensors are very popular for crop monitoring and yield prediction. This paper describes how satellite images with moderate (Landsat satellite data) and very high (QuickBird and WorldView-2 satellite data) spatial resolution, together with GreenSeeker hand held crop sensor, can be used to estimate yield and crop growth variability. Winter barley (2007 and 2015) and winter wheat (2009 and 2011) were chosen because of cloud-free data availability in the same time period for experimental field from Landsat satellite images and QuickBird or WorldView-2 images. Very high spatial resolution images were resampled to worse spatial resolution. Normalised difference vegetation index was derived from each satellite image data sets and it was also measured with GreenSeeker handheld crop sensor for the year 2015 only. Results showed that each satellite image data set can be used for yield and plant variability estimation. Nevertheless, better results, in comparison with crop yield, were obtained for images acquired in later phenological phases, e.g. in 2007 - BBCH 59 - average correlation coefficient 0.856, and in 2011 - BBCH 59-0.784. GreenSeeker handheld crop sensor was not suitable for yield estimation due to different measuring method.

Multilevel Mixture Kalman Filter

NASA Astrophysics Data System (ADS)

Guo, Dong; Wang, Xiaodong; Chen, Rong

2004-12-01

The mixture Kalman filter is a general sequential Monte Carlo technique for conditional linear dynamic systems. It generates samples of some indicator variables recursively based on sequential importance sampling (SIS) and integrates out the linear and Gaussian state variables conditioned on these indicators. Due to the marginalization process, the complexity of the mixture Kalman filter is quite high if the dimension of the indicator sampling space is high. In this paper, we address this difficulty by developing a new Monte Carlo sampling scheme, namely, the multilevel mixture Kalman filter. The basic idea is to make use of the multilevel or hierarchical structure of the space from which the indicator variables take values. That is, we draw samples in a multilevel fashion, beginning with sampling from the highest-level sampling space and then draw samples from the associate subspace of the newly drawn samples in a lower-level sampling space, until reaching the desired sampling space. Such a multilevel sampling scheme can be used in conjunction with the delayed estimation method, such as the delayed-sample method, resulting in delayed multilevel mixture Kalman filter. Examples in wireless communication, specifically the coherent and noncoherent 16-QAM over flat-fading channels, are provided to demonstrate the performance of the proposed multilevel mixture Kalman filter.

Quantification of peripheral and central blood pressure variability using a time-frequency method.

PubMed

Kouchaki, Z; Butlin, M; Qasem, A; Avolio, A P

2016-08-01

Systolic blood pressure variability (BPV) is associated with cardiovascular events. As the beat-to-beat variation of blood pressure is due to interaction of several cardiovascular control systems operating with different response times, assessment of BPV by spectral analysis using the continuous measurement of arterial pressure in the finger is used to differentiate the contribution of these systems in regulating blood pressure. However, as baroreceptors are centrally located, this study considered applying a continuous aortic pressure signal estimated noninvasively from finger pressure for assessment of systolic BPV by a time-frequency method using Short Time Fourier Transform (STFT). The average ratio of low frequency and high frequency power band (LF PB /HF PB ) was computed by time-frequency decomposition of peripheral systolic pressure (pSBP) and derived central aortic systolic blood pressure (cSBP) in 30 healthy subjects (25-62 years) as a marker of balance between cardiovascular control systems contributing in low and high frequency blood pressure variability. The results showed that the BPV assessed from finger pressure (pBPV) overestimated the BPV values compared to that assessed from central aortic pressure (cBPV) for identical cardiac cycles (P<;0.001), with the overestimation being greater at higher power.

Variability of AVHRR-Derived Clear-Sky Surface Temperature over the Greenland Ice Sheet.

NASA Astrophysics Data System (ADS)

Stroeve, Julienne; Steffen, Konrad

1998-01-01

The Advanced Very High Resolution Radiometer is used to derive surface temperatures for one satellite pass under clear skies over the Greenland ice sheet from 1989 through 1993. The results of these temperatures are presented as monthly means, and their spatial and temporal variability are discussed. Accuracy of the dry snow surface temperatures is estimated to be better than 1 K during summer. This error is expected to increase during polar night due to problems in cloud identification. Results indicate the surface temperature of the Greenland ice sheet is strongly dominated by topography, with minimum surface temperatures associated with the high elevation regions. In the summer, maximum surface temperatures occur during July along the western coast and southern tip of the ice sheet. Minimum temperatures are found at the summit during summer and move farther north during polar night. Large interannual variability in surface temperatures occurs during winter associated with katabatic storm events. Summer temperatures show little variation, although 1992 stands out as being colder than the other years. The reason for the lower temperatures during 1992 is believed to be a result of the 1991 eruption of Mount Pinatubo.

X-ray Observations of the Bright Old Nova V603 Aquilae

NASA Technical Reports Server (NTRS)

Mukai, K.; Orio, M.

2004-01-01

We report on our Chandra and RXTE observations of the bright old nova, V603 Aql, performed in 2001 April, supplemented by our analysis of archival X-ray data on this object. We find that the RXTE data are contaminated by the Galactic Ridge X-ray emission. After accounting for this effect, we find a high level of aperiodic variability in the RXTE data, at a level consistent with the uncontaminated Chandra data. The Chandra HETG spectrum clearly originates in a multi-temperature plasma. We constrain the possible emission measure distribution of the plasma through a combination of global and local fits. The X-ray luminosity and the spectral shape of V603 Aql resemble those of SS Cyg in transition between quiescence and outburst. The fact that the X-ray flux variability is only weakly energy dependent can be interpreted by supposing that the variability is due to changes in the maximum temperature of the plasma. The plasma density is likely to be high, and the emission region is likely to be compact. Finally, the apparent overabundance of Ne is consistent with V603 Aql being a young system.

Optimal Control of Distributed Energy Resources using Model Predictive Control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mayhorn, Ebony T.; Kalsi, Karanjit; Elizondo, Marcelo A.

2012-07-22

In an isolated power system (rural microgrid), Distributed Energy Resources (DERs) such as renewable energy resources (wind, solar), energy storage and demand response can be used to complement fossil fueled generators. The uncertainty and variability due to high penetration of wind makes reliable system operations and controls challenging. In this paper, an optimal control strategy is proposed to coordinate energy storage and diesel generators to maximize wind penetration while maintaining system economics and normal operation. The problem is formulated as a multi-objective optimization problem with the goals of minimizing fuel costs and changes in power output of diesel generators, minimizingmore » costs associated with low battery life of energy storage and maintaining system frequency at the nominal operating value. Two control modes are considered for controlling the energy storage to compensate either net load variability or wind variability. Model predictive control (MPC) is used to solve the aforementioned problem and the performance is compared to an open-loop look-ahead dispatch problem. Simulation studies using high and low wind profiles, as well as, different MPC prediction horizons demonstrate the efficacy of the closed-loop MPC in compensating for uncertainties in wind and demand.« less

Microstructural Features Controlling the Variability in Low-Cycle Fatigue Properties of Alloy Inconel 718DA at Intermediate Temperature

NASA Astrophysics Data System (ADS)

Texier, Damien; Gómez, Ana Casanova; Pierret, Stéphane; Franchet, Jean-Michel; Pollock, Tresa M.; Villechaise, Patrick; Cormier, Jonathan

2016-03-01

The low-cycle fatigue behavior of two direct-aged versions of the nickel-based superalloy Inconel 718 (IN718DA) was examined in the low-strain amplitude regime at intermediate temperature. High variability in fatigue life was observed, and abnormally short lifetimes were systematically observed to be due to crack initiation at (sub)-surface non-metallic inclusions. However, crack initiation within (sub)-surface non-metallic inclusions did not necessarily lead to short fatigue life. The macro- to micro-mechanical mechanisms of deformation and damage have been examined by means of detailed microstructural characterization, tensile and fatigue mechanical tests, and in situ tensile testing. The initial stages of crack micro-propagation from cracked non-metallic particles into the surrounding metallic matrix occupies a large fraction of the fatigue life and requires extensive local plastic straining in the matrix adjacent to the cracked inclusions. Differences in microstructure that influence local plastic straining, i.e., the δ-phase content and the grain size, coupled with the presence of non-metallic inclusions at the high end of the size distribution contribute strongly to the fatigue life variability.

The support of long wavelength loads on Venus

NASA Astrophysics Data System (ADS)

Benerdt, W. B.; Saunders, R. S.

1985-04-01

One of the great surprises of the Pioneer Venus mission was the high degree of correlation between topography and gravity found at all wavelengths. This implies a close relationship between topography and lateral subsurface density anomalies, such as those due to passive or dynamic compensation. Sleep-Phillips type compensation model with a variable crustal thickness and a variable upper mantle density was developed. The thin shell theory was used to investigate three end member cases: (1) loading by topographic construction, resulting in a downward deflection of the surface (no mantle support); (2) completely compensated support of a constructional load (no surface deflection); and (3) topography due entirely to upward deflection of the surface supported by a low density upper mantle (no surface load). In general, the models imply relatively thick crust and dense upper mantle for Ishtar Terra and Ovda Regio (western Aphrodite), thinned crust and buoyant upper mantle for Tethus Regio and regions near Sappho and Alpha Regio, and a nearly uniform crust with a buoyant upper mantle for Beta Regio and Atla Regio (eastern Aphrodite).

Driving performance changes of middle-aged experienced taxi drivers due to distraction tasks during unexpected situations.

PubMed

Kim, Hyung-Sik; Choi, Mi-Hyun; Choi, Jin-Seung; Kim, Hyun-Joo; Hong, Sang-Pyo; Jun, Jae-Hoon; Tack, Gye-Rae; Kim, Boseong; Min, Ung-Chan; Lim, Dae-Woon; Chung, Soon-Cheol

2013-10-01

This study investigated the effects of distraction taskssuch as sending a text message with a cellphone and searching navigation with car navigation system-on the driving performance of 29 highly experienced taxi drivers in their 50s. All participants were instructed to drive using a driving simulator for 2 min. while maintaining a constant distance from the vehicle in front and a constant speed. Participants drove without any distractions for the first minute. For an additional minute, they performed Driving Only or performed a task while driving (Driving + Sending Text Message or Driving + Searching Navigation). An unexpected situation, in which the participant had to stop abruptly due to a sudden stop of the preceding vehicle, occurred during this period. Driving performance during the unexpected situation was evaluated by car control variables, medial-lateral coefficient of variation and brake time, and by motion variables such as the jerk-cost function. Compared to Driving Only, jerk-cost function, medial-lateral coefficient of variation, and brake time increased during Driving + Sending Text Message or Driving + Searching Navigation.

Use of Stirred Suspension Bioreactors for Male Germ Cell Enrichment.

PubMed

Sakib, Sadman; Dores, Camila; Rancourt, Derrick; Dobrinski, Ina

2016-01-01

Spermatogenesis is a stem cell based system. Both therapeutic and biomedical research applications of spermatogonial stem cells require a large number of cells. However, there are only few germ line stem cells in the testis, contained in the fraction of undifferentiated spermatogonia. The lack of specific markers makes it difficult to isolate these cells. The long term maintenance and proliferation of nonrodent germ cells in culture has so far been met with limited success, partially due to the lack of highly enriched starting populations. Differential plating, which depends on the differential adhesion properties of testicular somatic and germ cells to tissue culture dishes, has been the method of choice for germ cell enrichment, especially for nonrodent germ cells. However, for large animals, this process becomes labor intensive and increases variability due to the need for extensive handling. Here, we describe the use of stirred suspension bioreactors, as a novel system for enriching undifferentiated germ cells from 1-week-old pigs. This method capitalizes on the adherent properties of somatic cells within a controlled environment, thus promoting the enrichment of progenitor cells with minimal handling and variability.

The Support of Long Wavelength Loads on Venus

NASA Technical Reports Server (NTRS)

Benerdt, W. B.; Saunders, R. S.

1985-01-01

One of the great surprises of the Pioneer Venus mission was the high degree of correlation between topography and gravity found at all wavelengths. This implies a close relationship between topography and lateral subsurface density anomalies, such as those due to passive or dynamic compensation. Sleep-Phillips type compensation model with a variable crustal thickness and a variable upper mantle density was developed. The thin shell theory was used to investigate three end member cases: (1) loading by topographic construction, resulting in a downward deflection of the surface (no mantle support); (2) completely compensated support of a constructional load (no surface deflection); and (3) topography due entirely to upward deflection of the surface supported by a low density upper mantle (no surface load). In general, the models imply relatively thick crust and dense upper mantle for Ishtar Terra and Ovda Regio (western Aphrodite), thinned crust and buoyant upper mantle for Tethus Regio and regions near Sappho and Alpha Regio, and a nearly uniform crust with a buoyant upper mantle for Beta Regio and Atla Regio (eastern Aphrodite).

Experimental and theoretical investigation of temperature-dependent electrical fatigue studies on 1-3 type piezocomposites

NASA Astrophysics Data System (ADS)

Mohan, Y.; Arockiarajan, A.

2016-03-01

1-3 type piezocomposites are very attractive materials for transducers and biomedical application, due to its high electromechanical coupling effects. Reliability study on 1-3 piezocomposites subjected to cyclic loading condition in transducer application is one of the primary concern. Hence, this study focuses on 1-3 piezocomposites for various PZT5A1 fiber volume fraction subjected to electrical fatigue loading up-to 106 cycles and at various elevated temperature. Initially experiments are performed on 1-3 piezocomposites, in order to understand the degradation phenomena due to various range in amplitude of electric fields (unipolar & bipolar), frequency of applied electric field and for various ambient temperature. Performing experiments for high cycle fatigue and for different fiber volume fraction of PZT5A1 is a time consuming process. Hence, a simplified macroscopic uni-axial model based on physical mechanisms of domain switching and continuum damage mechanics has been developed to predict the non-linear fatigue behaviour of 1-3 piezocomposites for temperature dependent electrical fatigue loading conditions. In this model, damage effects namely domain pinning, frozen domains and micro cracks, are considered as a damage variable (ω). Remnant variables and material properties are considered as a function of internal damage variable and the growth of the damage is derived empirically based on the experimental observation to predict the macroscopic changes in the properties. The measured material properties and dielectric hysteresis (electric displacement vs. electric field) as well as butterfly curves (longitudinal strain vs. electric field) are compared with the simulated results. It is observed that variation in amplitude of bipolar electric field and temperature has a strong influence on the response of 1-3 piezocomposites.

The role of sex and body weight on the metabolic effects of high-fat diet in C57BL/6N mice.

PubMed

Ingvorsen, C; Karp, N A; Lelliott, C J

2017-04-10

Metabolic disorders are commonly investigated using knockout and transgenic mouse models on the C57BL/6N genetic background due to its genetic susceptibility to the deleterious metabolic effects of high-fat diet (HFD). There is growing awareness of the need to consider sex in disease progression, but limited attention has been paid to sexual dimorphism in mouse models and its impact in metabolic phenotypes. We assessed the effect of HFD and the impact of sex on metabolic variables in this strain. We generated a reference data set encompassing glucose tolerance, body composition and plasma chemistry data from 586 C57BL/6N mice fed a standard chow and 733 fed a HFD collected as part of a high-throughput phenotyping pipeline. Linear mixed model regression analysis was used in a dual analysis to assess the effect of HFD as an absolute change in phenotype, but also as a relative change accounting for the potential confounding effect of body weight. HFD had a significant impact on all variables tested with an average absolute effect size of 29%. For the majority of variables (78%), the treatment effect was modified by sex and this was dominated by male-specific or a male stronger effect. On average, there was a 13.2% difference in the effect size between the male and female mice for sexually dimorphic variables. HFD led to a significant body weight phenotype (24% increase), which acts as a confounding effect on the other analysed variables. For 79% of the variables, body weight was found to be a significant source of variation, but even after accounting for this confounding effect, similar HFD-induced phenotypic changes were found to when not accounting for weight. HFD and sex are powerful modifiers of metabolic parameters in C57BL/6N mice. We also demonstrate the value of considering body size as a covariate to obtain a richer understanding of metabolic phenotypes.

QT variability strongly predicts sudden cardiac death in asymptomatic subjects with mild or moderate left ventricular systolic dysfunction: a prospective study.

PubMed

Piccirillo, Gianfranco; Magrì, Damiano; Matera, Sabrina; Magnanti, Marzia; Torrini, Alessia; Pasquazzi, Eleonora; Schifano, Erika; Velitti, Stefania; Marigliano, Vincenzo; Quaglione, Raffaele; Barillà, Francesco

2007-06-01

The most widely accepted marker for stratifying the risk of sudden cardiac death (SCD) in post myocardial infarction patients is a depressed left ventricular function. Left ventricular ejection fractions (EF) of 35% or less increase the risk of sudden death but values between 35 and 40% raise concern. The underlying pathophysiological mechanism is sustained ventricular tachycardia or fibrillation, both associated with increased cardiac repolarization variability. We assessed whether the indices of QT variability from a short-term electrocardiographic (ECG) recording predict sudden death. A total of 396 subjects with chronic heart failure (CHF) due to post-ischaemic cardiomyopathy, with an EF between 35 and 40% and in NYHA class I, underwent a 5 min ECG recording to calculate the following variables: QT variance (QT(v)), QT normalized for the square of the mean QT (QTVN), and QT variability index (QTVI). Corrected QT (QT(c)) was calculated from a 12-lead ECG recording. All participants were followed for 5 years. A multivariable survival model indicated that a QTVI greater than or equal to the 80th percentile indicated a high risk of SCD [hazards ratio (HR) 4.6, 95% confidence interval (CI) 1.5-13.4, P = 0.006] and, though to a lesser extent, a high risk of total mortality (HR 2.4, 95% CI 1.2-4.9, P = 0.017). The model including QTVI as a continuous variable confirmed a similar high risk for SCD (HR 2.9, 95% CI 1.3-6.5, P = 0.01) and for total mortality (HR 2.6, 95% CI 1.3-5.2, P = 0.008). Although asymptomatic patients with CHF who have a slightly depressed EF are at low risk of sudden death, the category is extraordinarily numerous. The QTVI could be helpful in stratifying the risk of sudden death in this otherwise undertreated population.

Evaluating the variability in surface water reservoir planning characteristics during climate change impacts assessment

NASA Astrophysics Data System (ADS)

Soundharajan, Bankaru-Swamy; Adeloye, Adebayo J.; Remesan, Renji

2016-07-01

This study employed a Monte-Carlo simulation approach to characterise the uncertainties in climate change induced variations in storage requirements and performance (reliability (time- and volume-based), resilience, vulnerability and sustainability) of surface water reservoirs. Using a calibrated rainfall-runoff (R-R) model, the baseline runoff scenario was first simulated. The R-R inputs (rainfall and temperature) were then perturbed using plausible delta-changes to produce simulated climate change runoff scenarios. Stochastic models of the runoff were developed and used to generate ensembles of both the current and climate-change-perturbed future runoff scenarios. The resulting runoff ensembles were used to force simulation models of the behaviour of the reservoir to produce 'populations' of required reservoir storage capacity to meet demands, and the performance. Comparing these parameters between the current and the perturbed provided the population of climate change effects which was then analysed to determine the variability in the impacts. The methodology was applied to the Pong reservoir on the Beas River in northern India. The reservoir serves irrigation and hydropower needs and the hydrology of the catchment is highly influenced by Himalayan seasonal snow and glaciers, and Monsoon rainfall, both of which are predicted to change due to climate change. The results show that required reservoir capacity is highly variable with a coefficient of variation (CV) as high as 0.3 as the future climate becomes drier. Of the performance indices, the vulnerability recorded the highest variability (CV up to 0.5) while the volume-based reliability was the least variable. Such variabilities or uncertainties will, no doubt, complicate the development of climate change adaptation measures; however, knowledge of their sheer magnitudes as obtained in this study will help in the formulation of appropriate policy and technical interventions for sustaining and possibly enhancing water security for irrigation and other uses served by Pong reservoir.

Peptide-based protein capture agents with high affinity, selectivity, and stability as antibody replacements in biodetection assays

NASA Astrophysics Data System (ADS)

Coppock, Matthew B.; Farrow, Blake; Warner, Candice; Finch, Amethist S.; Lai, Bert; Sarkes, Deborah A.; Heath, James R.; Stratis-Cullum, Dimitra

2014-05-01

Current biodetection assays that employ monoclonal antibodies as primary capture agents exhibit limited fieldability, shelf life, and performance due to batch-to-batch production variability and restricted thermal stability. In order to improve upon the detection of biological threats in fieldable assays and systems for the Army, we are investigating protein catalyzed capture (PCC) agents as drop-in replacements for the existing antibody technology through iterative in situ click chemistry. The PCC agent oligopeptides are developed against known protein epitopes and can be mass produced using robotic methods. In this work, a PCC agent under development will be discussed. The performance, including affinity, selectivity, and stability of the capture agent technology, is analyzed by immunoprecipitation, western blotting, and ELISA experiments. The oligopeptide demonstrates superb selectivity coupled with high affinity through multi-ligand design, and improved thermal, chemical, and biochemical stability due to non-natural amino acid PCC agent design.

How predictable are equatorial Atlantic surface winds?

NASA Astrophysics Data System (ADS)

Richter, Ingo; Doi, Takeshi; Behera, Swadhin

2017-04-01

Sensitivity tests with the SINTEX-F general circulation model (GCM) as well as experiments from the Coupled Model Intercomparison Project phase 5 (CMIP5) are used to examine the extent to which sea-surface temperature (SST) anomalies contribute to the variability and predictability of monthly mean surface winds in the equatorial Atlantic. In the SINTEX-F experiments, a control experiment with prescribed observed SST for the period 1982-2014 is modified by inserting climatological values in certain regions, thereby eliminating SST anomalies. When SSTs are set to climatology in the tropical Atlantic only (30S to 30N), surface wind variability over the equatorial Atlantic (5S-5N) decreases by about 40% in April-May-June (AMJ). This suggests that about 60% of surface wind variability is due to either internal atmospheric variability or SSTs anomalies outside the tropical Atlantic. A further experiment with climatological SSTs in the equatorial Pacific indicates that another 10% of variability in AMJ may be due to remote influences from that basin. Experiments from the CMIP5 archive, in which climatological SSTs are prescribed globally, tend to confirm the results from SINTEX-F but show a wide spread. In some models, the equatorial Atlantic surface wind variability decreases by more than 90%, while in others it even increases. Overall, the results suggest that about 50-60% of surface wind variance in AMJ is predictable, while the rest is due to internal atmospheric variability. Other months show significantly lower predictability. The relatively strong internal variability as well as the influence of remote SSTs suggest a limited role for coupled ocean-atmosphere feedbacks in equatorial Atlantic variability.

Dynamics of melanoma tumor therapy with vesicular stomatitis virus: explaining the variability in outcomes using mathematical modeling.

PubMed

Rommelfanger, D M; Offord, C P; Dev, J; Bajzer, Z; Vile, R G; Dingli, D

2012-05-01

Tumor selective, replication competent viruses are being tested for cancer gene therapy. This approach introduces a new therapeutic paradigm due to potential replication of the therapeutic agent and induction of a tumor-specific immune response. However, the experimental outcomes are quite variable, even when studies utilize highly inbred strains of mice and the same cell line and virus. Recognizing that virotherapy is an exercise in population dynamics, we utilize mathematical modeling to understand the variable outcomes observed when B16ova malignant melanoma tumors are treated with vesicular stomatitis virus in syngeneic, fully immunocompetent mice. We show how variability in the initial tumor size and the actual amount of virus delivered to the tumor have critical roles on the outcome of therapy. Virotherapy works best when tumors are small, and a robust innate immune response can lead to superior tumor control. Strategies that reduce tumor burden without suppressing the immune response and methods that maximize the amount of virus delivered to the tumor should optimize tumor control in this model system.

New Observations of the Martian Ionosphere and its Variability - An Overview

NASA Astrophysics Data System (ADS)

Kopf, Andrew J.

2017-04-01

The Martian ionosphere is a highly variable system, owed to the strong influence of the Sun on its properties and behavior, particularly at higher altitudes. Recent measurements from the MAVEN and Mars Express spacecraft have allowed for a more complete understanding of the ionosphere and its variability from two different perspectives. Due to the low-altitude periapsis of its orbit, MAVEN has allowed for the first in-situ ionospheric studies since Viking, yielding detailed direct measurements of the ionosphere's structure, composition, and dynamics, as well as its rate of loss to space. Mars Express has over a decade of continuous ionospheric observation of the red planet, with the unique ability to remotely sound the ionosphere. These features enable Mars Express to make long-period ionospheric measurements on each orbit, at all local times and solar zenith angles. Utilized together, these two spacecraft form a powerful observational suite that has provided new insights into this dynamic environment. This talk will highlight several important recent results in the study of the Martian ionosphere and its variability.

Resolving the Large Scale Spectral Variability of the Luminous Seyfert 1 Galaxy 1H 0419-577

NASA Technical Reports Server (NTRS)

Pounds, K. A.; Reeves, J. N.; Page, K. L.; OBrien, P. T.

2004-01-01

An XMM-Newton observation of the luminous Seyfert 1 galaxy 1H 0419-577 in September 2002, when the source was in an extreme low-flux state, found a very hard X-ray spectrum at 1-10 keV with a strong soft excess below approximately 1 keV. Comparison with an earlier XMM-Newton observation when 1H 0419-577 was X-ray bright indicated the dominant spectral variability was due to a steep power law or cool Comptonized thermal emission. Four further XMM-Newton observations, with 1H 0419-577 in intermediate flux states, now support that conclusion, while we also find the variable emission component in intermediate state difference spectra to be strongly modified by absorption in low ionisation matter. The variable soft excess is seen to be an artefact of absorption of the underlying continuum while the core soft emission is attributed to recombination in an extended region of more highly ionised gas. This new analysis underlines the importance of fully accounting for absorption in characterizing AGN X-ray spectra.

Laser welding process in PP moulding parts: Evaluation of seam performance

NASA Astrophysics Data System (ADS)

Oliveira, N.; Pontes, A. J.

2015-12-01

The Polypropylene is one of the most versatile polymer materials used in the industry. Due to this versatility, it is possible to use it in different products. This material can also be mixed with several additives namely glass fiber, carbon nanotubes, etc. This compatibility with different additives allows also obtaining products with characteristics that goes from an impact absorber to an electricity conductor. When is necessary to join components in PP they could be welded through hot plate, ultrasonic weld and also by laser. This study had the objective of study the influence of several variables, capable of influence the final quality of the seam. In this case were studied variables of the injection molding process as mold temperature and cooling time. Was also studied laser welding variables and different materials. The results showed that the variables that have the most influence were mould temperature, laser velocity and laser diameter. The seams were analyzed using Optical Microscopy technique. The seams showed perfect contact between the materials analyzed, despite the high standard variation presented in the mechanical testes.

Bioavailability and pharmacokinetic profile of grape pomace phenolic compounds in humans.

PubMed

Castello, Fabio; Costabile, Giuseppina; Bresciani, Letizia; Tassotti, Michele; Naviglio, Daniele; Luongo, Delia; Ciciola, Paola; Vitale, Marilena; Vetrani, Claudia; Galaverna, Gianni; Brighenti, Furio; Giacco, Rosalba; Del Rio, Daniele; Mena, Pedro

2018-05-15

Grape pomace, the major byproduct of the wine and juice industry, is a relevant source of bioactive phenolic compounds. However, polyphenol bioavailability in humans is not well understood, and the inter-individual variability in the production of phenolic metabolites has not been comprehensively assessed to date. The pharmacokinetic and excretive profiles of phenolic metabolites after the acute administration of a drink made from red grape pomace was here investigated in ten volunteers. A total of 35 and 28 phenolic metabolites were quantified in urine and plasma, respectively. The main circulating metabolites included phenyl-γ-valerolactones, hydroxybenzoic acids, simple phenols, hydroxyphenylpropionic acids, hydroxycinnamates, and (epi)catechin phase II conjugates. A high inter-individual variability was shown both in urine and plasma samples, and different patterns of circulating metabolites were unravelled by applying unsupervised multivariate analysis. Besides the huge variability in the production of microbial metabolites of colonic origin, an important variability was observed due to phase II conjugates. These results are of interest to further understand the potential health benefits of phenolic metabolites on individual basis. Copyright © 2018 Elsevier Inc. All rights reserved.

Relationship between low and high frequencies in the \\delta Scuti star KIC 9764965

NASA Astrophysics Data System (ADS)

Rostopchina, A.; Breger, M.

2014-10-01

Two years of Kepler spacecraft data of the \\delta Sct/\\gamma Dor star KIC 9764965 revealed 67 statistically significant frequencies from 0.45 to 59.17 c d-1 (0.005 to 0.685 mHz). The 19 low frequencies do not show equidistant period spacing predicted for gravity modes of successive radial order. We note a favored frequency spacing of 2.053 c d-1 that appears in both the low-frequency (gravity mode) region and high-frequency (pressure mode) regions. The value of this frequency spacing also occurs as a dominant low frequency and in a high-frequency triplet. A peak at exactly twice the value of the 2.053 c d-1 mode is shown not to be a Fourier harmonic of the low-frequency peak due to a different amplitude variability. This behavior is also seen in other \\delta Sct stars. The test for resonant mode coupling between low and high frequencies could not be carried out due to the small amplitudes of the peaks, making it difficult to separate the parent and child modes.

Long-Term Variability in o Ceti and Other Mira Variables: Signs of Supergranular Convection?

NASA Astrophysics Data System (ADS)

Templeton, Matthew R.; Karovska, Margarita

2009-09-01

We describe our study of long-term variability of o Ceti (Mira A), the prototype of the Mira-type pulsating stars. Our study was originally undertaken to search for coherent long-period variability, but the results of our analysis didn't uncover this. However, we detected a low-frequency ``red noise'' in the Fourier spectrum of the o Ceti century-long light curve. We have since found similar behavior in other Miras and pulsating giant stars and have begun a study of a large sample of Mira variables. Similar red noise has been previously detected in red supergiants and attributed to supergranular convection. Its presence in Miras suggests the phenomenon may be ubiquitous in cool giant pulsators. These results support high-angular resolution observations of Miras and supergiants showing asymmetries in their surface brightness distributions, which may be due to large supergranular convection cells. Theoretical modeling, and numerical simulations of pulsation processes in late-type giants and supergiants should therefore take into account the effects of deep convection and large supergranular structures, which in turn may provide important insights into the behavior of Miras and other giant and supergiant pulsators. In this work, we summarize our results for o Ceti, present preliminary results of our broader study of Mira variables, and discuss how the results of this study may be used by future studies of AGB variables.

Late Holocene sea level variability and Atlantic Meridional Overturning Circulation

USGS Publications Warehouse

Cronin, Thomas M.; Farmer, Jesse R.; Marzen, R. E.; Thomas, E.; Varekamp, J.C.

2014-01-01

Pre-twentieth century sea level (SL) variability remains poorly understood due to limits of tide gauge records, low temporal resolution of tidal marsh records, and regional anomalies caused by dynamic ocean processes, notably multidecadal changes in Atlantic Meridional Overturning Circulation (AMOC). We examined SL and AMOC variability along the eastern United States over the last 2000 years, using a SL curve constructed from proxy sea surface temperature (SST) records from Chesapeake Bay, and twentieth century SL-sea surface temperature (SST) relations derived from tide gauges and instrumental SST. The SL curve shows multidecadal-scale variability (20–30 years) during the Medieval Climate Anomaly (MCA) and Little Ice Age (LIA), as well as the twentieth century. During these SL oscillations, short-term rates ranged from 2 to 4 mm yr−1, roughly similar to those of the last few decades. These oscillations likely represent internal modes of climate variability related to AMOC variability and originating at high latitudes, although the exact mechanisms remain unclear. Results imply that dynamic ocean changes, in addition to thermosteric, glacio-eustatic, or glacio-isostatic processes are an inherent part of SL variability in coastal regions, even during millennial-scale climate oscillations such as the MCA and LIA and should be factored into efforts that use tide gauges and tidal marsh sediments to understand global sea level rise.

A Binary Nature of the Marginal CP Star Sigma Sculptoris

NASA Astrophysics Data System (ADS)

Janík, Jan; Krtička, Jiří; Mikulášek, Zdeněk; Zverko, Juraj; Pintado, Olga; Paunzen, Ernst; Prvák, Milan; Skalický, Jan; Zejda, Miloslav; Adam, Christian

2018-05-01

The A2 V star σ Scl was suspected of being a low-amplitude rotating variable of the Ap-type star by several authors. Aiming to decide whether the star is a variable chemically peculiar (CP) star, we searched for the photometric and spectroscopic variability, and determined chemical abundances of σ Scl. The possible variability was tested using several types of periodograms applied to the photometry from Long-Term Photometry of Variables project (LTPV) and Hipparcos. Sixty spectrograms of high signal-to-noise (S/N) were obtained and used for chemical analysis of the stellar atmosphere and for looking for spectral variability that is symptomatic for the CP stars. We did not find any signs of the light variability or prominent chemical peculiarity, that is specific for the CP stars. The only exception is the abundance of scandium, which is significantly lower than the solar one and yttrium and barium, which are strongly overabundant. As a by-product of the analysis, and with the addition of 29 further spectra, we found that σ Scl is a single-lined spectroscopic binary with orbital period of 46.877(8) d. We argue that σ Scl is not an Ap star, but rather a marginal Am star in SB1 system. The spectral energy distribution of the binary reveals infrared excess due to circumstellar material.

Uncertainties in Past and Future Global Water Availability

NASA Astrophysics Data System (ADS)

Sheffield, J.; Kam, J.

2014-12-01

Understanding how water availability changes on inter-annual to decadal time scales and how it may change in the future under climate change are a key part of understanding future stresses on water and food security. Historic evaluations of water availability on regional to global scales are generally based on large-scale model simulations with their associated uncertainties, in particular for long-term changes. Uncertainties are due to model errors and missing processes, parameter uncertainty, and errors in meteorological forcing data. Recent multi-model inter-comparisons and impact studies have highlighted large differences for past reconstructions, due to different simplifying assumptions in the models or the inclusion of physical processes such as CO2 fertilization. Modeling of direct anthropogenic factors such as water and land management also carry large uncertainties in their physical representation and from lack of socio-economic data. Furthermore, there is little understanding of the impact of uncertainties in the meteorological forcings that underpin these historic simulations. Similarly, future changes in water availability are highly uncertain due to climate model diversity, natural variability and scenario uncertainty, each of which dominates at different time scales. In particular, natural climate variability is expected to dominate any externally forced signal over the next several decades. We present results from multi-land surface model simulations of the historic global availability of water in the context of natural variability (droughts) and long-term changes (drying). The simulations take into account the impact of uncertainties in the meteorological forcings and the incorporation of water management in the form of reservoirs and irrigation. The results indicate that model uncertainty is important for short-term drought events, and forcing uncertainty is particularly important for long-term changes, especially uncertainty in precipitation due to reduced gauge density in recent years. We also discuss uncertainties in future projections from these models as driven by bias-corrected and downscaled CMIP5 climate projections, in the context of the balance between climate model robustness and climate model diversity.

A dynamic model of the radiation-belt electron phase-space density based on POLAR/HIST measurements

NASA Astrophysics Data System (ADS)

Vassiliadis, D.; Green, J. C.

2007-12-01

The response of the energetic-electron phase-space density (PSD) in the radiation belts is subject to a delicate combination of acceleration and loss processes which are strongly determined by the magnetospheric configuration and field disturbance level. We quantify the response of the density to stormtime fields as observed by the HIST detector on board POLAR. Several distinct modes are identified, characterized by peak second- and third- adiabatic invariants and peak delay time. The modes represent quasiadiabatic transport due to ring current activity; high L* (~6), day-long acceleration linked to ULF wave-particle interaction; and low-L* (~3), minute- to hour-long acceleration interpreted to be due to transient inductive fields or VLF wave-particle interaction. The net transport due to these responses is not always or everywhere diffusive, therefore we quantify the degree of departure from diffusive transport for specific storm intervals and radial ranges. Taken together the response modes comprise a dynamic, nonlinear model which allows us to better understand the historic variability of the high-energy tail of the electron distribution in the inner magnetosphere.

Highly variable cutis laxa resulting from a dominant splicing mutation of the elastin gene.

PubMed

Graul-Neumann, Luitgard M; Hausser, Ingrid; Essayie, Maximilian; Rauch, Anita; Kraus, Cornelia

2008-04-15

Autosomal dominant congenital cutis laxa (ADCL) is genetically heterogeneous and shows clinical variability. Only seven ADCL families with mutations in the elastin gene (ELN) have been described previously. We present morphological and molecular genetic studies in a cutis laxa kindred with a previously undescribed highly variable phenotype caused by a novel ELN mutation c.1621 C > T. The proband presented with severe cutis laxa, severe congenital lung disease previously undescribed in ADCL and pulmonary artery disease, which is often seen in ARCL but rare in ADCL. He also developed infantile spasms (OMIM 308350; West syndrome), which we consider a coincidental association although recessive cutis laxa or even digenic inheritance cannot be excluded. Electron microscopy of the proband's dermis revealed only mild rarefication of elastic fibers (in contrast to most recessive cutis laxa types). Apart from mild elastic fiber fragmentation, dermal morphology of the proband's father was within normal range. Molecular analysis of the ELN gene using genomic DNA from blood and RNA from cultured skin fibroblasts indicated a novel splice site mutation in the proband and his clinically healthy father. Analysis of ELN expression in fibroblasts provided evidence for a dominant-negative effect in the child, while due to an unknown mechanism, the father showed haploinsufficiency which might explain the significant clinical variability. Copyright 2008 Wiley-Liss, Inc.

ATLAS: A High-cadence All-sky Survey System

NASA Astrophysics Data System (ADS)

Tonry, J. L.; Denneau, L.; Heinze, A. N.; Stalder, B.; Smith, K. W.; Smartt, S. J.; Stubbs, C. W.; Weiland, H. J.; Rest, A.

2018-06-01

Technology has advanced to the point that it is possible to image the entire sky every night and process the data in real time. The sky is hardly static: many interesting phenomena occur, including variable stationary objects such as stars or QSOs, transient stationary objects such as supernovae or M dwarf flares, and moving objects such as asteroids and the stars themselves. Funded by NASA, we have designed and built a sky survey system for the purpose of finding dangerous near-Earth asteroids (NEAs). This system, the “Asteroid Terrestrial-impact Last Alert System” (ATLAS), has been optimized to produce the best survey capability per unit cost, and therefore is an efficient and competitive system for finding potentially hazardous asteroids (PHAs) but also for tracking variables and finding transients. While carrying out its NASA mission, ATLAS now discovers more bright (m < 19) supernovae candidates than any ground based survey, frequently detecting very young explosions due to its 2 day cadence. ATLAS discovered the afterglow of a gamma-ray burst independent of the high energy trigger and has released a variable star catalog of 5 × 106 sources. This is the first of a series of articles describing ATLAS, devoted to the design and performance of the ATLAS system. Subsequent articles will describe in more detail the software, the survey strategy, ATLAS-derived NEA population statistics, transient detections, and the first data release of variable stars and transient light curves.

Variability in home mechanical ventilation prescription.

PubMed

Escarrabill, Joan; Tebé, Cristian; Espallargues, Mireia; Torrente, Elena; Tresserras, Ricard; Argimón, J

2015-10-01

Few studies have analyzed the prevalence and accessibility of home mechanical ventilation (HMV). The aim of this study was to characterize the prevalence of HMV and variability in prescriptions from administrative data. Prescribing rates of HMV in the 37 healthcare sectors of the Catalan Health Service were compared from billing data from 2008 to 2011. Crude accumulated activity rates (per 100,000 population) were calculated using systematic component of variation (SCV) and empirical Bayes (EB) methods. Standardized activity ratios (SAR) were described using a map of healthcare sectors. A crude rate of 23 HMV prescriptions per 100,000 population was observed. Rates increase with age and have increased by 39%. Statistics measuring variation not due to chance show a high variation in women (CSV=0.20 and EB=0.30) and in men (CSV=0.21 and EB=0.40), and were constant over time. In a multilevel Poisson model, hospitals with a chest unit were associated with a greater number of cases (beta=0.68, P<.0001). High variability in prescribing HMV can be explained, in part, by the attitude of professionals towards treatment and accessibility to specialist centers with a chest unit. Analysis of administrative data and variability mapping help identify unexplained variations and, in the absence of systematic records, are a feasible way of tracking treatment. Copyright © 2014 SEPAR. Published by Elsevier Espana. All rights reserved.

Perspectives on NO, NOy, and fine aerosol sources and variability during SONEX

NASA Astrophysics Data System (ADS)

Thompson, Anne M.; Sparling, Lynn C.; Kondo, Yutaka; Anderson, Bruce E.; Gregory, Gerald L.; Sachse, Glen W.

Distributions of upper tropospheric tracer data on each of the 14 science flights of SONEX (SASS [Subsonics Assessment] Ozone and Nitrogen Oxides Experiment) provide a statistical overview of NO, NOy and fine aerosol variability during SONEX (an aircraft mission conducted in October and November 1997). The wide range of variability of NO from all sources provides a perspective on the aircraft perturbation. Background distributions of NOy are somewhat elevated inside flight corridors relative to outside; fine aerosol and NO/NOy in and out of corridors are similar. The potential vorticity of air sampled during SONEX is low relative to the NAFC (North Atlantic Flight Corridor) as a whole, due either to advection of lower latitude air into the corridor or biases in sampling to avoid the stratosphere. High NO/NOy (>0.4) from fresh lightning and aircraft sources was usually associated with pv much lower than the NAFC as a whole. Air masses identified as tropospheric by a low ozone criterion nevertheless have high pv, a marker for stratospheric air. Thus, stratospheric and surface sources also contribute to overall variability. A statistically robust assessment of the relative aircraft NO contribution during SONEX, based on data alone, is unlikely, given the mixture of other NO sources within which the aircraft signal is embedded. This underscores the need for more data and modeling studies.

Influence of environmental variables on diffusive greenhouse gas fluxes at hydroelectric reservoirs in Brazil.

PubMed

Rogério, J P; Santos, M A; Santos, E O

2013-11-01

For almost two decades, studies have been under way in Brazil, showing how hydroelectric reservoirs produce biogenic gases, mainly methane (CH4) and carbon dioxide (CO2), through the organic decomposition of flooded biomass. This somewhat complex phenomenon is due to a set of variables with differing levels of interdependence that directly or indirectly affect greenhouse gas (GHG) emissions. The purpose of this paper is to determine, through a statistical data analysis, the relation between CO2, CH4 diffusive fluxes and environmental variables at the Furnas, Itumbiara and Serra da Mesa hydroelectric reservoirs, located in the Cerrado biome on Brazil's high central plateau. The choice of this region was prompted by its importance in the national context, covering an area of some two million square kilometers, encompassing two major river basins (Paraná and Tocantins-Araguaia), with the largest installed power generation capacity in Brazil, together accounting for around 23% of Brazilian territory. This study shows that CH4 presented a moderate negative correlation between CO2 and depth. Additionally, a moderate positive correlation was noted for pH, water temperature and wind. The CO2 presented a moderate negative correlation for pH, wind speed, water temperature and air temperature. Additionally, a moderate positive correlation was noted for CO2 and water temperature. The complexity of the emission phenomenon is unlikely to occur through a simultaneous understanding of all the factors, due to difficulties in accessing and analyzing all the variables that have real, direct effects on GHG production and emission.

Attributing uncertainty in streamflow simulations due to variable inputs via the Quantile Flow Deviation metric

NASA Astrophysics Data System (ADS)

Shoaib, Syed Abu; Marshall, Lucy; Sharma, Ashish

2018-06-01

Every model to characterise a real world process is affected by uncertainty. Selecting a suitable model is a vital aspect of engineering planning and design. Observation or input errors make the prediction of modelled responses more uncertain. By way of a recently developed attribution metric, this study is aimed at developing a method for analysing variability in model inputs together with model structure variability to quantify their relative contributions in typical hydrological modelling applications. The Quantile Flow Deviation (QFD) metric is used to assess these alternate sources of uncertainty. The Australian Water Availability Project (AWAP) precipitation data for four different Australian catchments is used to analyse the impact of spatial rainfall variability on simulated streamflow variability via the QFD. The QFD metric attributes the variability in flow ensembles to uncertainty associated with the selection of a model structure and input time series. For the case study catchments, the relative contribution of input uncertainty due to rainfall is higher than that due to potential evapotranspiration, and overall input uncertainty is significant compared to model structure and parameter uncertainty. Overall, this study investigates the propagation of input uncertainty in a daily streamflow modelling scenario and demonstrates how input errors manifest across different streamflow magnitudes.

BONA FIDE, STRONG-VARIABLE GALACTIC LUMINOUS BLUE VARIABLE STARS ARE FAST ROTATORS: DETECTION OF A HIGH ROTATIONAL VELOCITY IN HR CARINAE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Groh, J. H.; Damineli, A.; Moises, A. P.

2009-11-01

We report optical observations of the luminous blue variable (LBV) HR Carinae which show that the star has reached a visual minimum phase in 2009. More importantly, we detected absorptions due to Si IV lambdalambda4088-4116. To match their observed line profiles from 2009 May, a high rotational velocity of v{sub rot} approx = 150 +- 20 km s{sup -1} is needed (assuming an inclination angle of 30 deg.), implying that HR Car rotates at approx =0.88 +- 0.2 of its critical velocity for breakup (v{sub crit}). Our results suggest that fast rotation is typical in all strong-variable, bona fide galacticmore » LBVs, which present S-Dor-type variability. Strong-variable LBVs are located in a well-defined region of the HR diagram during visual minimum (the 'LBV minimum instability strip'). We suggest this region corresponds to where v{sub crit} is reached. To the left of this strip, a forbidden zone with v{sub rot}/v{sub crit}>1 is present, explaining why no LBVs are detected in this zone. Since dormant/ex LBVs like P Cygni and HD 168625 have low v{sub rot}, we propose that LBVs can be separated into two groups: fast-rotating, strong-variable stars showing S-Dor cycles (such as AG Car and HR Car) and slow-rotating stars with much less variability (such as P Cygni and HD 168625). We speculate that supernova (SN) progenitors which had S-Dor cycles before exploding (such as in SN 2001ig, SN 2003bg, and SN 2005gj) could have been fast rotators. We suggest that the potential difficulty of fast-rotating Galactic LBVs to lose angular momentum is additional evidence that such stars could explode during the LBV phase.« less

Frequency of sister-chromatid exchange among greenhouse farmers exposed to pesticides.

PubMed

Shaham, J; Kaufman, Z; Gurvich, R; Levi, Z

2001-04-05

Sister-chromatid exchange (SCE) was measured in peripheral lymphocytes of 104 greenhouse farmers exposed to pesticides and 44 unexposed workers. The results of SCEs are expressed in two variables: (a) mean number of SCEs per chromosome and, (b) proportion of high frequency cells (cells with more than eight SCEs). A high correlation was found between these two variables. The adjusted means of both SCEs variables were significantly higher among the farmers compared with the unexposed group (P < 0.01). Adjustment was made for smoking, age, education, and origin. The adjusted means of both SCE variables, were significantly elevated (P < 0.05) among the farmers who prepared and applied more than 70% of the pesticides by themselves compared with those who prepared and applied less than 70% of the pesticides by themselves. Both SCEs variables were also significantly elevated (P < 0.05) among farmers who were involved in more than 7.4 sprays per year compared with those with 7.4 or less sprays per year (P < 0.05). We found a tendency towards elevation of the two variables of SCEs among those who did not use protective measures while preparing the pesticides. Evaluation of the influence of years of exposure on the frequency of SCEs showed that the two variables of SCEs were higher among those farmers who were exposed to pesticides for more than 21 years than among those with less than 21 years of exposure. The variables that had the most influence on the elevation of SCEs were self-preparation of the pesticide mixtures and the number of sprayings per year. Because the farmers used a mixture of almost 24 different chemical classes it was impossible to attribute exposure to a specific pesticide or group of pesticides to single farmers. Our finding of a significant increase of SCEs frequency in peripheral lymphocytes in greenhouse farmers indicates a potential cytogenetic hazard due to pesticides exposure.

Evaluation of a highly discriminating multiplex multi-locus variable-number of tandem-repeats (MLVA) analysis for Vibrio cholerae.

PubMed

Olsen, Jaran S; Aarskaug, Tone; Skogan, Gunnar; Fykse, Else Marie; Ellingsen, Anette Bauer; Blatny, Janet M

2009-09-01

Vibrio cholerae is the etiological agent of cholera and may be used in bioterror actions due to the easiness of its dissemination, and the public fear for acquiring the cholera disease. A simple and highly discriminating method for connecting clinical and environmental isolates of V. cholerae is needed in microbial forensics. Twelve different loci containing variable numbers of tandem-repeats (VNTRs) were evaluated in which six loci were polymorphic. Two multiplex reactions containing PCR primers targeting these six VNTRs resulted in successful DNA amplification of 142 various environmental and clinical V. cholerae isolates. The genetic distribution inside the V. cholerae strain collection was used to evaluate the discriminating power (Simpsons Diversity Index=0.99) of this new MLVA analysis, showing that the assay have a potential to differentiate between various strains, but also to identify those isolates which are collected from a common V. cholerae outbreak. This work has established a rapid and highly discriminating MLVA assay useful for track back analyses and/or forensic studies of V. cholerae infections.

Variable Pitch Darrieus Water Turbines

NASA Astrophysics Data System (ADS)

Kirke, Brian; Lazauskas, Leo

In recent years the Darrieus wind turbine concept has been adapted for use in water, either as a hydrokinetic turbine converting the kinetic energy of a moving fluid in open flow like an underwater wind turbine, or in a low head or ducted arrangement where flow is confined, streamtube expansion is controlled and efficiency is not subject to the Betz limit. Conventional fixed pitch Darrieus turbines suffer from two drawbacks, (i) low starting torque and (ii) shaking due to cyclical variations in blade angle of attack. Ventilation and cavitation can also cause problems in water turbines when blade velocities are high. Shaking can be largely overcome by the use of helical blades, but these do not produce large starting torque. Variable pitch can produce high starting torque and high efficiency, and by suitable choice of pitch regime, shaking can be minimized but not entirely eliminated. Ventilation can be prevented by avoiding operation close to a free surface, and cavitation can be prevented by limiting blade velocities. This paper summarizes recent developments in Darrieus water turbines, some problems and some possible solutions.

Factors associated with the deposition of Cladophora on Lake Michigan beaches in 2012

USGS Publications Warehouse

Riley, Stephen C.; Tucker, Taaja R.; Adams, Jean V.; Fogarty, Lisa R.; Lafrancois, Brenda Moraska

2015-01-01

Deposition of the macroalgae Cladophora spp. was monitored on 18 beaches around Lake Michigan during 2012 at a high temporal frequency. We observed a high degree of spatial variability in Cladophora deposition among beaches on Lake Michigan, even within local regions, with no clear regional pattern in the intensity of Cladophora deposition. A strong seasonal pattern in Cladophora deposition was observed, with the heaviest deposition occurring during mid-summer. Several beaches exhibited high temporal variability in Cladophora deposition over short time scales, suggesting that drifting algal mats may be extremely dynamic in nearshore environments of the Great Lakes. Cladophora deposition on Lake Michigan beaches was primarily related to the presence of nearshore structures, local population density, and nearshore bathymetry. There was relatively little evidence that waves, winds, or currents were associated with Cladophora deposition on beaches, but this may be due to the relatively poor resolution of existing nearshore hydrodynamic data. Developing a predictive understanding of beach-cast Cladophora dynamics in Great Lakes environments may require both intensive Cladophora monitoring and fine-scale local hydrodynamic modeling efforts.

Wildfires and geochemical change in a subalpine forest over the past six millennia

NASA Astrophysics Data System (ADS)

Leys, Bérangère; Higuera, Philip E.; McLauchlan, Kendra K.; Dunnette, Paul V.

2016-12-01

The frequency of large wildfires in western North America has been increasing in recent decades, yet the geochemical impacts of these events are poorly understood. The multidecadal timescales of both disturbance-regime variability and ecosystem responses make it challenging to study the effects of fire on terrestrial nutrient cycling. Nonetheless, disturbance-mediated changes in nutrient concentrations could ultimately limit forest productivity over centennial to millennial time scales. Here, we use a novel approach that combines quantitative elemental analysis of lake sediments using x-ray fluorescence to assess the geochemical impacts of high-severity fires in a 6200 year long sedimentary record from a small subalpine lake in Rocky Mountain National Park, Colorado, USA. Immediately after 17 high-severity fires, the sedimentary concentrations of five elements increased (Ti, Ca, K, Al, and P), but returned to pre-fire levels within three decades. Multivariate analyses indicate that erosion of weathered mineral material from the catchment is a primary mechanism though which high-severity fires impact element cycling. A longer-term trend in sediment geochemistry was also identified over millennial time scales. This decrease in the concentrations of six elements (Al, Si, K, Ti, Mn, and Fe) over the past 6200 years may have been due to a decreased rate of high-severity fires, long-term ecosystem development, or changes in precipitation regime. Our results indicate that high-severity fire events can determine elemental concentrations in subalpine forests. The degree of variability in geochemical response across time scales suggests that shifting rates of high-severity burning can cause significant changes in key rock-derived nutrients. To our knowledge, these results are the first to reveal repeated loss of rock-derived nutrients from the terrestrial ecosystem due to high-severity fires. Understanding the future of fire-prone coniferous forests requires further documentation and quantification of this important mechanism linking fire regimes and biogeochemical cycles.

EVIDENCE FOR PHOTOIONIZATION-DRIVEN BROAD ABSORPTION LINE VARIABILITY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Tinggui; Yang, Chenwei; Wang, Huiyuan

2015-12-01

We present a qualitative analysis of the variability of quasar broad absorption lines using the large multi-epoch spectroscopic data set of the Sloan Digital Sky Survey Data Release 10. We confirm that variations of absorption lines are highly coordinated among different components of the same ion or the same absorption component of different ions for C iv, Si iv, and N v. Furthermore, we show that the equivalent widths (EWs) of the lines decrease or increase statistically when the continuum brightens or dims. This is further supported by the synchronized variations of emission and absorption-line EWs when the well-established intrinsicmore » Baldwin effect for emission lines is taken into account. We find that the emergence of an absorption component is usually accompanied by the dimming of the continuum while the disappearance of an absorption-line component is accompanied by the brightening of the continuum. This suggests that the emergence or disappearance of a C iv absorption component is only the extreme case, when the ionic column density is very sensitive to continuum variations or the continuum variability the amplitude is larger. These results support the idea that absorption-line variability is driven mainly by changes in the gas ionization in response to continuum variations, that the line-absorbing gas is highly ionized, and in some extreme cases, too highly ionized to be detected in UV absorption lines. Due to uncertainties in the spectroscopic flux calibration, we cannot quantify the fraction of quasars with asynchronized continuum and absorption-line variations.« less

Assessment of co-composting process with high load of an inorganic industrial waste.

PubMed

Soares, Micaela A R; Quina, Margarida J; Reis, Marco S; Quinta-Ferreira, Rosa

2017-01-01

This study aims to investigate the co-composting of an inorganic industrial waste (eggshell - ES) in very high levels (up to 60% w/w). Since composting is a process in which solid, liquid and gaseous phases interact in a very complex way, there is a need to shed light on statistical tools that can unravel the main relationships structuring the variability associated to this process. In this study, PCA and data visualisation were used with that purpose. The co-composting tests were designed with increasing quantities of ES (0, 10, 20, 30 and 60%ES w/w) mixed with industrial potato peel and rice husks. Principal component analysis showed that physical properties like free air space, bulk density and moisture are the most relevant variables for explaining the variability due to ES content. On the other hand, variability in time dynamics is mostly driven by some chemical and phytoxicological parameters, such as organic matter decay and nitrate content. Higher ES incorporation (60% ES) enhanced the initial biological activity of the mixture, but the higher bulk density and lower water holding capacity had a negative effect on the aerobic biological activity as the process evolved. Nevertheless, pathogen-killing temperatures (>70°C for 11h) were attained. All the final products obtained after 90days were stable and non-phytotoxic. This work proved that valorisation of high amounts of eggshell by co-composting is feasible, but prone to be influenced by the physical properties of the mixtures. Copyright © 2016 Elsevier Ltd. All rights reserved.

Chromosomal variation in Argentine populations of Akodon montensis Thomas, 1913 (Rodentia, Cricetidae, Sigmodontinae)

PubMed Central

Malleret, Matías Maximiliano; Labaroni, Carolina Alicia; García, Gabriela Verónica; Ferro, Juan Martín; Martí, Dardo Andrea; Lanzone, Cecilia

2016-01-01

Abstract The genus Akodon Meyen, 1833 is one of the most species-rich among sigmodontine rodents and has great chromosome variability. Akodon montensis has a relatively broad distribution in South America, and Argentine populations are located in the southernmost region of its range. Brazilian populations have important chromosomal variability, but cytogenetic data from Argentina are scarce. We performed a chromosome characterization of natural populations of Akodon montensis using conventional staining, C-banding, Ag-NORs and base-specific fluorochromes. A total of 31 specimens from five localities of Misiones Province, in Argentina, were analyzed. The 2n=24 chromosomes was the most frequently observed karyotype. However, five individuals presented 25 chromosomes due to a supernumerary B-chromosome; and one individual had 2n=26 due to one B plus a trisomy for chromosome 11. Additionally, two XY females and two variants of the X chromosomes were found. C-positive centromeric bands occurred in all chromosomes; additional C-bands were observed in some autosomes, the X, Y and B chromosomes. Ag-NORs were observed in five autosomes, and the B chromosome was frequently marked. Fluorochrome banding was similar among karyotypes of the analyzed populations. Comparisons of cytogenetic data among populations of Argentina and Brazil showed the presence of high intraspecific variability in Akodon montensis and some differences among regions. PMID:27186343

Abiotic characteristics and microalgal dynamics in South Africa's largest estuarine lake during a wet to dry transitional phase

NASA Astrophysics Data System (ADS)

Nunes, Monique; Adams, Janine B.; Bate, Guy C.; Bornman, Thomas G.

2017-11-01

The summer of 2012/2013 signified the end of the dry phase in the St Lucia estuarine system that lasted for over a decade. The increased rainfall coupled with the partial re-connection of the Mfolozi River to the estuarine system shifted St Lucia to a new limnetic state. With the increased availability of habitat due to the higher water level, it was expected that microalgal biomass and abundance would rapidly increase through recruitment from refuge areas i.e. South Lake and new introductions. Microalgal and physico-chemical data were collected at three sites within the Mfolozi/Msunduzi River and at 23 sites within the St Lucia estuarine system between June 2014 and February 2015. Results from this study indicated low biomass for both phytoplankton (<5 μg l-1) and microphytobenthos (<60 mg m-2) because of local and external drivers. These included limited nutrient and light availability, variable water residence times, biomass dilution and heterogeneity of the sediment. The high spatio-temporal variability limits the effectiveness of using the microalgal communities to detect change in the estuarine lake. In addition, significant intrasystem differences were observed between the three main lake basins and Narrows, due to the influence of the freshwater input from the Mfolozi River. This study provides insight into the spatio-temporal variability of physico-chemical conditions and microalgal communities during the 2014-2015 limnetic state.

Scavenging Rate Ecoassay: A Potential Indicator of Estuary Condition

PubMed Central

Porter, Augustine G.; Scanes, Peter R.

2015-01-01

Monitoring of estuary condition is essential due to the highly productive and often intensely impacted nature of these ecosystems. Assessment of the physico-chemical condition of estuaries is expensive and difficult due to naturally fluctuating water quality and biota. Assessing the vigour of ecosystem processes is an alternative method with potential to overcome much of the variability associated with physico-chemical measures. Indicators of estuary condition should have small spatial and temporal variability, have a predictable response to perturbation and be ecologically relevant. Here, we present tests of the first criterion, the spatio-temporal variability of a potential ecoassay measuring the rate of scavenging in estuaries. We hypothesised that the proposed scavenging ecoassay would not vary significantly among A) sites in an estuary, B) trips separated by weeks, or C) days in a trip. Because not all habitats are present in all estuaries, this test was undertaken in two habitats. When conducted over bare substrate there were occasional significant differences, but no discernible patterns, within levels of the experiment. When conducted over vegetated substrate, days within a trip did not vary significantly, but later trips experienced greater scavenging. This scavenging ecoassay shows potential as a tool for assessing the condition of estuarine ecosystems, and further exploration of this protocol is warranted by implementation in estuaries across a gradient of anthropogenic stress. PMID:26024225

Impact of topography on groundwater salinization due to ocean surge inundation

NASA Astrophysics Data System (ADS)

Yu, Xuan; Yang, Jie; Graf, Thomas; Koneshloo, Mohammad; O'Neal, Michael A.; Michael, Holly A.

2016-08-01

Sea-level rise and increases in the frequency and intensity of ocean surges caused by climate change are likely to exacerbate adverse effects on low-lying coastal areas. The landward flow of water during ocean surges introduces salt to surficial coastal aquifers and threatens groundwater resources. Coastal topographic features (e.g., ponds, dunes, barrier islands, and channels) likely have a strong impact on overwash and salinization processes, but are generally highly simplified in modeling studies. To understand topographic impacts on groundwater salinization, we modeled a theoretical overwash event and variable-density groundwater flow and salt transport in 3-D using the fully coupled surface and subsurface numerical simulator, HydroGeoSphere. The model simulates the coastal aquifer as an integrated system considering overland flow, coupled surface and subsurface exchange, variably saturated flow, and variable-density groundwater flow. To represent various coastal landscape types, we simulated both synthetic fields and real-world coastal topography from Delaware, USA. The groundwater salinization assessment suggested that the topographic connectivity promoting overland flow controls the volume of aquifer that is salinized. In contrast, the amount of water that can be stored in surface depressions determines the amount of seawater that infiltrates the subsurface and the time for seawater to flush from the aquifer. Our study suggests that topography has a significant impact on groundwater salinization due to ocean surge overwash, with important implications for coastal land management and groundwater vulnerability assessment.

Contrasting subtropical PV intrusion frequency and their impact on tropospheric Ozone distribution over Pacific Ocean in El-Niño and La-Niña conditions.

PubMed

Nath, Debashis; Chen, Wen; Graf, Hans-F; Lan, Xiaoqiang; Gong, Hainan

2017-09-20

Upper tropospheric equatorial westerly ducts over the Pacific Ocean are the preferred location for Rossby wave breaking events during boreal winter and spring. These subtropical wave breaking events lead to the intrusion of high PV (potential vorticity) air along the extra-tropical tropopause and transport ozone rich dry stratospheric air into the tropics. The intrusion frequency has strong interannual variability due to ENSO (El-Niño/Southern Oscillation), with more events under La-Niña and less under El-Niño conditions. This may result from stronger equatorial westerly ducts and subtropical jets during La-Niña and weaker during El-Niño. It was previously suggested that the interannual variability of the tropospheric ozone distribution over the central-eastern Pacific Ocean is mainly driven by convective activity related to ENSO and that the barotropic nature of the subtropical intrusions restricts the tracers within the UT. However, our analysis shows that tropospheric ozone concentration and subtropical intrusions account ~65% of the co- variability (below 5 km) in the outer tropical (10-25°N) central Pacific Ocean, particularly during La-Niña conditions. Additionally, we find a two-fold increase and westward shift in the intrusion frequency over the Pacific Ocean, due to the climate regime shift in SST pattern during 1997/98.

Iceland-Scotland Overflow Water transport variability through the Charlie-Gibbs Fracture Zone and the impact of the North Atlantic Current

NASA Astrophysics Data System (ADS)

Bower, Amy; Furey, Heather

2017-09-01

The Charlie-Gibbs Fracture Zone (CGFZ), a deep and wide gap in the Mid-Atlantic Ridge near 52°N, is a gateway between the eastern and western subpolar regions for the Atlantic Meridional Overturning Circulation (AMOC). In 2010-2012, an eight-mooring array of current meters and temperature/salinity sensors was installed across the CGFZ between 500 m and the sea floor to measure the mean transport of westward-flowing Iceland-Scotland Overflow Water (ISOW) and investigate the impact of the eastward-flowing North Atlantic Current (NAC) on ISOW transport variability. The 22 month record mean ISOW transport through the CGFZ, -1.7 ± 0.5 Sv (95% confidence interval), is 30% lower than the previously published estimate based on 13 months of current-only measurements, -2.4 ± 1.2 Sv. The latter mean estimate may have been biased high due to the lack of continuous salinity measurements, although the two estimates are not statistically different due to strong mesoscale variability in both data sets. Empirical Orthogonal Function analysis and maps of satellite-derived absolute dynamic topography show that weak westward ISOW transport events and eastward reversals are caused by northward meanders of the NAC, with its deep-reaching eastward velocities. These results add to growing evidence that a significant fraction of ISOW exits the Iceland Basin by routes other than the CGFZ.

Application of Spectral Analysis Techniques in the Intercomparison of Aerosol Data. Part II: Using Maximum Covariance Analysis to Effectively Compare Spatiotemporal Variability of Satellite and AERONET Measured Aerosol Optical Depth

NASA Technical Reports Server (NTRS)

Li, Jing; Carlson, Barbara E.; Lacis, Andrew A.

2014-01-01

Moderate Resolution Imaging SpectroRadiometer (MODIS) and Multi-angle Imaging Spectroradiomater (MISR) provide regular aerosol observations with global coverage. It is essential to examine the coherency between space- and ground-measured aerosol parameters in representing aerosol spatial and temporal variability, especially in the climate forcing and model validation context. In this paper, we introduce Maximum Covariance Analysis (MCA), also known as Singular Value Decomposition analysis as an effective way to compare correlated aerosol spatial and temporal patterns between satellite measurements and AERONET data. This technique not only successfully extracts the variability of major aerosol regimes but also allows the simultaneous examination of the aerosol variability both spatially and temporally. More importantly, it well accommodates the sparsely distributed AERONET data, for which other spectral decomposition methods, such as Principal Component Analysis, do not yield satisfactory results. The comparison shows overall good agreement between MODIS/MISR and AERONET AOD variability. The correlations between the first three modes of MCA results for both MODIS/AERONET and MISR/ AERONET are above 0.8 for the full data set and above 0.75 for the AOD anomaly data. The correlations between MODIS and MISR modes are also quite high (greater than 0.9). We also examine the extent of spatial agreement between satellite and AERONET AOD data at the selected stations. Some sites with disagreements in the MCA results, such as Kanpur, also have low spatial coherency. This should be associated partly with high AOD spatial variability and partly with uncertainties in satellite retrievals due to the seasonally varying aerosol types and surface properties.

A UV-to-MIR monitoring of DR Tau: Exploring how water vapor in the planet formation region is affected by stellar accretion variability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Banzatti, A.; Meyer, M. R.; Manara, C. F.

2014-01-01

Young stars are known to show variability due to non-steady mass accretion rate from their circumstellar disks. Accretion flares can produce strong energetic irradiation and heating that may affect the disk in the planet formation region, close to the central star. During an extreme accretion outburst in the young star EX Lupi, the prototype of EXor variables, remarkable changes in molecular gas emission from ∼1 AU in the disk have recently been observed. Here, we focus on water vapor and explore how it is affected by variable accretion luminosity in T Tauri stars. We monitored a young highly variable solar-massmore » star, DR Tau, using simultaneously two high/medium-resolution spectrographs at the European Southern Observatory Very Large Telescope: VISIR at 12.4 μm to observe water lines from the disk and X-shooter covering from 0.3 to 2.5 μm to constrain the stellar accretion. Three epochs spanning timescales from several days to several weeks were obtained. The accretion luminosity was estimated to change within a factor of ∼2 and no change in water emission was detected at a significant level. In comparison with EX Lupi and EXor outbursts, DR Tau suggests that the less long-lived and weaker variability phenomena typical of T Tauri stars may leave water at planet-forming radii in the disk mostly unaffected. We propose that these systems may provide evidence for two processes that act over different timescales: ultraviolet photochemistry in the disk atmosphere (faster) and heating of the deeper disk layers (slower).« less

Rainfall variability over southern Africa: an overview of current research using satellite and climate model data

NASA Astrophysics Data System (ADS)

Williams, C.; Kniveton, D.; Layberry, R.

2009-04-01

It is increasingly accepted that any possible climate change will not only have an influence on mean climate but may also significantly alter climatic variability. A change in the distribution and magnitude of extreme rainfall events (associated with changing variability), such as droughts or flooding, may have a far greater impact on human and natural systems than a changing mean. This issue is of particular importance for environmentally vulnerable regions such as southern Africa. The subcontinent is considered especially vulnerable to and ill-equipped (in terms of adaptation) for extreme events, due to a number of factors including extensive poverty, famine, disease and political instability. Rainfall variability is a function of scale, so high spatial and temporal resolution data are preferred to identify extreme events and accurately predict future variability. In this research, satellite-derived rainfall data are used as a basis for undertaking model experiments using a state-of-the-art climate model, run at both high and low spatial resolution. Once the model's ability to reproduce extremes has been assessed, idealised regions of sea surface temperature (SST) anomalies are used to force the model, with the overall aim of investigating the ways in which SST anomalies influence rainfall extremes over southern Africa. In this paper, a brief overview is given of the authors' research to date, pertaining to southern African rainfall. This covers (i) a description of present-day rainfall variability over southern Africa; (ii) a comparison of model simulated daily rainfall with the satellite-derived dataset; (iii) results from sensitivity testing of the model's domain size; and (iv) results from the idealised SST experiments.

Obliquity Variations of Habitable Zone Planets Kepler-62f and Kepler-186f

NASA Astrophysics Data System (ADS)

Shan, Yutong; Li, Gongjie

2018-06-01

Obliquity variability could play an important role in the climate and habitability of a planet. Orbital modulations caused by planetary companions and the planet’s spin axis precession due to the torque from the host star may lead to resonant interactions and cause large-amplitude obliquity variability. Here we consider the spin axis dynamics of Kepler-62f and Kepler-186f, both of which reside in the habitable zone around their host stars. Using N-body simulations and secular numerical integrations, we describe their obliquity evolution for particular realizations of the planetary systems. We then use a generalized analytic framework to characterize regions in parameter space where the obliquity is variable with large amplitude. We find that the locations of variability are fine-tuned over the planetary properties and system architecture in the lower-obliquity regimes (≲40°). As an example, assuming a rotation period of 24 hr, the obliquities of both Kepler-62f and Kepler-186f are stable below ∼40°, whereas the high-obliquity regions (60°–90°) allow moderate variabilities. However, for some other rotation periods of Kepler-62f or Kepler-186f, the lower-obliquity regions could become more variable owing to resonant interactions. Even small deviations from coplanarity (e.g., mutual inclinations ∼3°) could stir peak-to-peak obliquity variations up to ∼20°. Undetected planetary companions and/or the existence of a satellite could also destabilize the low-obliquity regions. In all cases, the high-obliquity region allows for moderate variations, and all obliquities corresponding to retrograde motion (i.e., >90°) are stable.

Deposition efficiency of inhaled particles (15-5000 nm) related to breathing pattern and lung function: an experimental study in healthy children and adults.

PubMed

Rissler, Jenny; Gudmundsson, Anders; Nicklasson, Hanna; Swietlicki, Erik; Wollmer, Per; Löndahl, Jakob

2017-04-08

Exposure to airborne particles has a major impact on global health. The probability of these particles to deposit in the respiratory tract during breathing is essential for their toxic effects. Observations have shown that there is a substantial variability in deposition between subjects, not only due to respiratory diseases, but also among individuals with healthy lungs. The factors determining this variability are, however, not fully understood. In this study we experimentally investigate factors that determine individual differences in the respiratory tract depositions of inhaled particles for healthy subjects at relaxed breathing. The study covers particles of diameters 15-5000 nm and includes 67 subjects aged 7-70 years. A comprehensive examination of lung function was performed for all subjects. Principal component analyses and multiple regression analyses were used to explore the relationships between subject characteristics and particle deposition. A large individual variability in respiratory tract deposition efficiency was found. Individuals with high deposition of a certain particle size generally had high deposition for all particles <3500 nm. The individual variability was explained by two factors: breathing pattern, and lung structural and functional properties. The most important predictors were found to be breathing frequency and anatomical airway dead space. We also present a linear regression model describing the deposition based on four variables: tidal volume, breathing frequency, anatomical dead space and resistance of the respiratory system (the latter measured with impulse oscillometry). To understand why some individuals are more susceptible to airborne particles we must understand, and take into account, the individual variability in the probability of particles to deposit in the respiratory tract by considering not only breathing patterns but also adequate measures of relevant structural and functional properties.

China's water sustainability in the 21st century: a climate informed water risk assessment covering multi-sector water demands

NASA Astrophysics Data System (ADS)

Chen, X.; Devineni, N.; Lall, U.; Hao, Z.; Dong, L.; Ju, Q.; Wang, J.; Wang, S.

2013-08-01

China is facing a water resources crisis with growing concerns as to the reliable supply of water for agricultural, industrial and domestic needs. High inter-annual rainfall variability and increasing consumptive use across the country exacerbates the situation further and is a constraint on future development. For water sustainability, it is necessary to examine the differences in water demand and supply and their spatio-temporal distribution in order to quantify the dimensions of the water risk. Here, a detailed quantitative assessment of water risk as measured by the distribution of cumulated deficits for China is presented. Considering daily precipitation and temperature variability over fifty years and the current water demands, risk measures are developed to inform county level water deficits that account for both within year and across year variations in climate. We choose political rather than watershed boundaries since economic activity and water use are organized by county and the political process is best informed through that unit. The risk measures highlight North China Plain counties as highly water stressed. Regions with high water stress are typically the regions with high inter-annual variability in rainfall and now have depleted groundwater aquifers. The stress components due to agricultural, industrial and domestic water demands are illustrated separately to assess the vulnerability of particular sectors within the country to provide a basis for targeted policy analysis for reducing water stress.

Due-Window Assignment Scheduling with Variable Job Processing Times

PubMed Central

Wu, Yu-Bin

2015-01-01

We consider a common due-window assignment scheduling problem jobs with variable job processing times on a single machine, where the processing time of a job is a function of its position in a sequence (i.e., learning effect) or its starting time (i.e., deteriorating effect). The problem is to determine the optimal due-windows, and the processing sequence simultaneously to minimize a cost function includes earliness, tardiness, the window location, window size, and weighted number of tardy jobs. We prove that the problem can be solved in polynomial time. PMID:25918745

Therapeutic drug monitoring of psychotropic medications

PubMed Central

Mitchell, Philip B

2000-01-01

Therapeutic drug monitoring (TDM) of a number of psychotropic medications has proven to be of value, enabling minimization of the limitations of considerable genetic variability in their metabolism and the high rates of poor compliance with many psychiatric disorders. Therapeutic ranges have been established for lithium, some of the tricyclic antidepressants, and clozapine. TDM has also been shown to be useful in avoiding toxicity (as many psychotropics have narrow therapeutic indices), particularly that due to interactions with other compounds. PMID:10759685

Performance of Wireless Networks in Highly Reflective Rooms with Variable Absorption

DTIC Science & Technology

2014-09-01

methods used to take these measurements , and an analysis of the results. 1. Packet Internet Groper Packet Internet Groper (PING) is a utility that can...such as 802.15 Bluetooth and ZigBee [4]. The handsets used in many of these systems, especially 802.11- based devices, have complex ...phase shifts of the original signal due to differences in time of arrivals for the various multiple paths. The signal power fluctuates around a mean

Environmental and Spatial Influences on Biogeography and Community Structure of Benthic Diatoms

NASA Astrophysics Data System (ADS)

Plante, C.; Hill-Spanik, K.; Lowry, J.

2016-02-01

Several theoretical and practical reasons suggest that benthic microalgae could be useful bioindicators. For instance, an ideal indicator species or community would be associated with a given habitat due to local physical conditions or biotic interactions (i.e., `environmental filtering'), not due to dispersal limitation. Due to their small size, immense abundances, and reliance on passive dispersal, the popular notion about micro-organisms is that `Everything is everywhere, but, the environment selects' (Baas-Becking 1934). Although much recent research concerning planktonic bacteria and dispersal limitation has been conducted, very little in this regard is known about microeukaryotes, especially benthic microbes. The purpose of our study was to identify and compare spatial and environmental influences on benthic diatom community structure and biogeography. In summer 2015, sediment was sampled at various spatial scales from four barrier island beaches in South Carolina, USA, and high-throughput (Ion Torrent) DNA sequencing was used to characterize diatom assemblages. ANOSIM and principal coordinates analysis revealed that communities were statistically distinct on the four islands. Community dissimilarity was compared to both spatial distance and environmental differences to determine potential influences of these variables on community structure. We found that geographic distance had the strongest correlation with community similarity, with and without one anomalous location, while differences in temperature (air, water, and sediment), nutrients, organic matter, and turbidity also had significant but weaker relationships with community structure. Surprisingly, air temperature, which changes on very short time scales, appeared to be the environmental factor most strongly related to diatom species composition, potentially implicating some unmeasured variable (e.g., cloud cover). However, we also found that temperature and geographic distance were strongly correlated. Future research will expand the spatial scope of this preliminary study and employ techniques (partial Mantel tests) to control for co-variation among variables.

Multiple Intravenous Infusions Phase 2a: Ontario Survey

PubMed Central

Fan, Mark; Koczmara, Christine; Masino, Caterina; Cassano-Piché, Andrea; Trbovich, Patricia; Easty, Anthony

2014-01-01

Background Research conducted in earlier phases of this study prospectively identified a number of concerns related to the safe administration of multiple intravenous (IV) infusions in Ontario hospitals. Objective To investigate the potential prevalence of practices or policies that may contribute to the patient safety risks identified in Phase 1b of this study. Data Sources and Review Methods Sixty-four survey responses were analyzed from clinical units where multiple IV infusions may occur (e.g., adult intensive care units). Survey questions were organized according to the topics identified in Phase 1b as potential contributors to patient harm (e.g., labelling practices, patient transfer practices, secondary infusion policies). Results Survey results indicated suboptimal practices and policies in some clinical units, and variability in a number of infusion practices. Key areas of concern included the following: use of primary IV tubing without back check valves when administering secondary infusions administration of secondary infusions with/as high-alert continuous IV medications potential confusion about how IV tubing should be labelled to reflect replacement date and time interruptions to IV therapy due to IV pump and/or tubing changes when patients are transferred between clinical units coadministration of continuous or intermittent infusions on central venous pressure monitoring ports variability in respondents’ awareness of the infusion pump's bolus capabilities Limitations Due to the limited sample size, survey responses may not be representative of infusion practices across Ontario. Answers to some questions indicated that the intent of the questions might have been misunderstood. Due to a design error, 1 question about bolus administration methods was not shown to as many respondents as appropriate. Conclusions The Ontario survey revealed variability in IV infusion practice across the province and potential opportunities to improve safety. PMID:26257837

Ultrafast outflows disappear in high-radiation fields

NASA Astrophysics Data System (ADS)

Pinto, C.; Alston, W.; Parker, M. L.; Fabian, A. C.; Gallo, L. C.; Buisson, D. J. K.; Walton, D. J.; Kara, E.; Jiang, J.; Lohfink, A.; Reynolds, C. S.

2018-05-01

Ultrafast outflows (UFOs) are the most extreme winds launched by active galactic nuclei (AGN) due to their mildly relativistic speeds (˜0.1-0.3c) and are thought to significantly contribute to galactic evolution via AGN feedback. Their nature and launching mechanism are however not well understood. Recently, we have discovered the presence of a variable UFO in the narrow-line Seyfert 1 IRAS 13224-3809. The UFO varies in response to the brightness of the source. In this work we perform flux-resolved X-ray spectroscopy to study the variability of the UFO and found that the ionization parameter is correlated with the luminosity. In the brightest states the gas is almost completely ionized by the powerful radiation field and the UFO is hardly detected. This agrees with our recent results obtained with principal component analysis. We might have found the tip of the iceberg: the high ionization of the outflowing gas may explain why it is commonly difficult to detect UFOs in AGN and possibly suggest that we may underestimate their actual feedback. We have also found a tentative correlation between the outflow velocity and the luminosity, which is expected from theoretical predictions of radiation-pressure-driven winds. This trend is rather marginal due to the Fe XXV-XXVI degeneracy. Further work is needed to break such degeneracy through time-resolved spectroscopy.

A formal and data-based comparison of measures of motor-equivalent covariation.

PubMed

Verrel, Julius

2011-09-15

Different analysis methods have been developed for assessing motor-equivalent organization of movement variability. In the uncontrolled manifold (UCM) method, the structure of variability is analyzed by comparing goal-equivalent and non-goal-equivalent variability components at the level of elemental variables (e.g., joint angles). In contrast, in the covariation by randomization (CR) approach, motor-equivalent organization is assessed by comparing variability at the task level between empirical and decorrelated surrogate data. UCM effects can be due to both covariation among elemental variables and selective channeling of variability to elemental variables with low task sensitivity ("individual variation"), suggesting a link between the UCM and CR method. However, the precise relationship between the notion of covariation in the two approaches has not been analyzed in detail yet. Analysis of empirical and simulated data from a study on manual pointing shows that in general the two approaches are not equivalent, but the respective covariation measures are highly correlated (ρ > 0.7) for two proposed definitions of covariation in the UCM context. For one-dimensional task spaces, a formal comparison is possible and in fact the two notions of covariation are equivalent. In situations in which individual variation does not contribute to UCM effects, for which necessary and sufficient conditions are derived, this entails the equivalence of the UCM and CR analysis. Implications for the interpretation of UCM effects are discussed. Copyright © 2011 Elsevier B.V. All rights reserved.

Future projection of Indian summer monsoon variability under climate change scenario: An assessment from CMIP5 climate models

NASA Astrophysics Data System (ADS)

Sharmila, S.; Joseph, S.; Sahai, A. K.; Abhilash, S.; Chattopadhyay, R.

2015-01-01

In this study, the impact of enhanced anthropogenic greenhouse gas emissions on the possible future changes in different aspects of daily-to-interannual variability of Indian summer monsoon (ISM) is systematically assessed using 20 coupled models participated in the Coupled Model Inter-comparison Project Phase 5. The historical (1951-1999) and future (2051-2099) simulations under the strongest Representative Concentration Pathway have been analyzed for this purpose. A few reliable models are selected based on their competence in simulating the basic features of present-climate ISM variability. The robust and consistent projections across the selected models suggest substantial changes in the ISM variability by the end of 21st century indicating strong sensitivity of ISM to global warming. On the seasonal scale, the all-India summer monsoon mean rainfall is likely to increase moderately in future, primarily governed by enhanced thermodynamic conditions due to atmospheric warming, but slightly offset by weakened large scale monsoon circulation. It is projected that the rainfall magnitude will increase over core monsoon zone in future climate, along with lengthening of the season due to late withdrawal. On interannual timescales, it is speculated that severity and frequency of both strong monsoon (SM) and weak monsoon (WM) might increase noticeably in future climate. Substantial changes in the daily variability of ISM are also projected, which are largely associated with the increase in heavy rainfall events and decrease in both low rain-rate and number of wet days during future monsoon. On the subseasonal scale, the model projections depict considerable amplification of higher frequency (below 30 day mode) components; although the dominant northward propagating 30-70 day mode of monsoon intraseasonal oscillations may not change appreciably in a warmer climate. It is speculated that the enhanced high frequency mode of monsoon ISOs due to increased GHG induced warming may notably modulate the ISM rainfall in future climate. Both extreme wet and dry episodes are likely to intensify and regionally extend in future climate with enhanced propensity of short active and long break spells. The SM (WM) could also be more wet (dry) in future due to the increment in longer active (break) spells. However, future changes in the spatial pattern during active/break phase of SM and WM are geographically inconsistent among the models. The results point out the growing climate-related vulnerability over Indian subcontinent, and further suggest the requisite of profound adaptation measures and better policy making in future.

Change in the tropical cyclone activity around Korea by the East Asian summer monsoon

NASA Astrophysics Data System (ADS)

Choi, Jae-Won; Cha, Yumi; Kim, Jeoung-Yun

2017-12-01

Correlation between the frequency of summer tropical cyclones (TCs) affecting Korea and the East Asian summer monsoon index (EASMI) was analyzed over the last 37 years. A clear positive correlation existed between the two variables, and this high positive correlation remained unchanged even when excluding El Niño-Southern Oscillation (ENSO) years. To investigate the causes of the positive correlation between the two variables in non-ENSO years, after the 8 years with the highest EASMI (high EASMI years) and the 8 years with the lowest EASMI (low EASMI years) were selected, and the average difference between the two phases was analyzed. In high EASMI years, in the difference between the two phases regarding 850 and 500 hPa streamline, anomalous cyclones were reinforced in the tropical and subtropical western North Pacific, while anomalous anticyclones were reinforced in mid-latitude East Asian areas. Due to these two anomalous pressure systems, anomalous southeasterlies developed near Korea, with these anomalous southeasterlies playing the role of anomalous steering flows making the TCs head toward areas near Korea. In addition, a monsoon trough strengthened more eastward, and TCs in high EASMI years occurred more in east ward over the western North Pacific.