High temperature superconductor dc SQUID micro-susceptometer for room temperature objects

NASA Astrophysics Data System (ADS)

Faley, M. I.; Pratt, K.; Reineman, R.; Schurig, D.; Gott, S.; Atwood, C. G.; Sarwinski, R. E.; Paulson, D. N.; Starr, T. N.; Fagaly, R. L.

2004-05-01

We have developed a scanning magnetic microscope (SMM) with 25 µm resolution in spatial position for the magnetic features of room temperature objects. The microscope consists of a high-temperature superconductor (HTS) dc SQUID sensor, suspended in vacuum with a self-adjusting standoff, close spaced liquid nitrogen Dewar, X-Y scanning stage and a computer control system. The HTS SQUIDs were optimized for better spatial and field resolutions for operation at liquid nitrogen temperature. Measured inside a magnetic shield, the 10 pT Hz-1/2 typical noise of the SQUIDs is white down to frequencies of about 10 Hz, increasing up to about 20 pT Hz-1/2 at 1 Hz. The microscope is mounted on actively damped platforms, which negate vibrations from the environment as well as damping internal stepper motor noises. A high-resolution video telescope and a 1 µm precision z-axis positioning system allow a close positioning of the sample under the sensor. The ability of the sensors to operate in unshielded environmental conditions with magnetic fields up to about 15 G allowed us to perform 2D mapping of the local ac and dc susceptibility of the objects.

The Microwave SQUID Multiplexer

NASA Astrophysics Data System (ADS)

Mates, John Arthur Benson

2011-12-01

This thesis describes a multiplexer of Superconducting Quantum Interference Devices (SQUIDs) with low-noise, ultra-low power dissipation, and great scalability. The multiplexer circuit measures the magnetic flux in a large number of unshunted rf SQUIDs by coupling each SQUID to a superconducting microwave resonator tuned to a unique resonance frequency and driving the resonators from a common feedline. A superposition of microwave tones measures each SQUID simultaneously using only two coaxial cables between the cryogenic device and room temperature. This multiplexer will enable the instrumentation of arrays with hundreds of thousands of low-temperature detectors for new applications in cosmology, materials analysis, and nuclear non-proliferation. The driving application of the Microwave SQUID Multiplexer is the readout of large arrays of superconducting transition-edge sensors, by some figures of merit the most sensitive detectors of electromagnetic signals over a span of more than nine orders of magnitude in energy, from 40 GHz microwaves to 200 keV gamma rays. Modern transition-edge sensors have noise-equivalent power as low as 10-20 W / Hz1/2 and energy resolution as good as 2 eV at 6 keV. These per-pixel sensitivities approach theoretical limits set by the underlying signals, motivating a rapid increase in pixel count to access new science. Compelling applications, like the non-destructive assay of nuclear material for treaty verification or the search for primordial gravity waves from inflation use arrays of these detectors to increase collection area or tile a focal plane. We developed three generations of SQUID multiplexers, optimizing the first for flux noise 0.17 muPhi0 / Hz1/2, the second for input current noise 19 pA / Hz1/2, and the last for practical multiplexing of large arrays of cosmic microwave background polarimeters based on transition-edge sensors. Using the last design we demonstrated multiplexed readout of prototype polarimeters with the

Non-destructive Testing (NDT) of metal cracks using a high Tc rf-SQUID and eddy current method

NASA Technical Reports Server (NTRS)

Lu, D. F.; Fan, Chang-Xin; Ruan, J. Z.; Han, S. G.; Wong, K. W.; Sun, G. F.

1995-01-01

A SQUID is the most sensitive device to detect change in magnetic field. A nondestructive testing (NDT) device using high temperature SQUID's and eddy current method will be much more sensitive than those currently used eddy current systems, yet much cheaper than one with low temperature SQUID's. In this paper, we present our study of such a NDT device using a high temperature superconducting rf-SQUID as a gradiometer sensor. The result clearly demonstrates the expected sensitivity of the system, and indicates the feasibility of building a portable HTS SQUID NDT device with the help from cryocooler industry. Such a NDT device will have a significant impact on metal corrosion or crack detection technology.

Low field electron paramagnetic resonance imaging with SQUID detection

NASA Technical Reports Server (NTRS)

Hahn, Inseob (Inventor); Day, Peter K. (Inventor); Penanen, Konstantin I. (Inventor); Eom, Byeong H. (Inventor); Cohen, Mark S. (Inventor)

2012-01-01

In one embodiment, a flux transformer with a gradiometer pickup coil is magnetically coupled to a SQUID, and a SQUID array amplifier comprising a plurality of SQUIDs, connected in series, is magnetically coupled to the output of the SQUID. Other embodiments are described and claimed.

Subranging scheme for SQUID sensors

NASA Technical Reports Server (NTRS)

Penanen, Konstantin I. (Inventor)

2008-01-01

A readout scheme for measuring the output from a SQUID-based sensor-array using an improved subranging architecture that includes multiple resolution channels (such as a coarse resolution channel and a fine resolution channel). The scheme employs a flux sensing circuit with a sensing coil connected in series to multiple input coils, each input coil being coupled to a corresponding SQUID detection circuit having a high-resolution SQUID device with independent linearizing feedback. A two-resolution configuration (course and fine) is illustrated with a primary SQUID detection circuit for generating a fine readout, and a secondary SQUID detection circuit for generating a course readout, both having feedback current coupled to the respective SQUID devices via feedback/modulation coils. The primary and secondary SQUID detection circuits function and derive independent feedback. Thus, the SQUID devices may be monitored independently of each other (and read simultaneously) to dramatically increase slew rates and dynamic range.

A SQUID-based metal detector—comparison to coil and x-ray systems

NASA Astrophysics Data System (ADS)

Bick, M.; Sullivan, P.; Tilbrook, D. L.; Du, J.; Gnanarajan, S.; Leslie, K. E.; Foley, C. P.

2005-03-01

The presence of foreign metal bodies and fragments in foodstuff and pharmaceutical products is of major concern to producers. Further, hidden metal objects can pose threats to security. In particular, stainless steel is difficult to detect by conventional coil metal detectors due to its low conductivity. We have employed an HTS SQUID magnetometer for the detection of stainless steel particles which is based on the measurement of the remanent magnetization of the particle. Our aim was to determine the detection limits of HTS SQUID-based remote magnetometry, especially for food inspection purposes, and to make a comparison of this technique to commonly used eddy current coil and x-ray inspection systems. We show that the SQUID system's sensitivity to stainless steel fragments is significantly higher than that of coil systems if the samples are magnetized in a 100 mT magnetic field prior to detection. Further, it has a higher sensitivity than x-ray systems, depending on the density distribution of the product under inspection. A 0.6 mg piece of grade-316 stainless steel (a fragment of a hypodermic needle 0.5 mm long and 0.65 mm diameter) represents the detection limit of our system with a 150 × 150 mm2 inspection orifice.

Non-destructive testing (NDT) of metal cracks using a high Tc rf-SQUID and eddy current method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lu, D.F.; Fan, C.; Ruan, J.Z.

1994-12-31

A SQUID is the most sensitive device to detect change in magnetic field. A non-destructive testing (NDT) device using high temperature SQUIDs and eddy current method will be much more sensitive than those currently used eddy current systems, yet much cheaper than one with low temperature SQUIDs. In this paper, we present our study of such a NDT device using a high temperature superconducting rf-SQUID as a gradiometer sensor. The result clearly demonstrates the expected sensitivity of the system, and indicates the feasibility of building a portable HTS SQUID NDT device with the help from cryocooler industry. Such a NDTmore » device will have a significant impact on metal corrosion or crack detection technology.« less

A Spread-Spectrum SQUID Multiplexer

NASA Astrophysics Data System (ADS)

Irwin, K. D.; Chaudhuri, S.; Cho, H.-M.; Dawson, C.; Kuenstner, S.; Li, D.; Titus, C. J.; Young, B. A.

2018-06-01

The transition-edge sensor (TES) is a mature, high-resolution x-ray spectrometer technology that provides a much higher efficiency than dispersive spectrometers such as gratings and crystal spectrometers. As larger arrays are developed, time-division multiplexing schemes operating at MHz frequencies are being replaced by microwave SQUID multiplexers using frequency-division multiplexing at GHz frequencies. However, the multiplexing factor achievable with microwave SQUIDs is limited by the high slew rate on the leading edge of x-ray pulses. In this paper, we propose a new multiplexing scheme for high-slew-rate TES x-ray calorimeters: the spread-spectrum SQUID multiplexer, which has the potential to enable higher multiplexing factors, especially in applications with lower photon-arrival rates.

Design, fabrication and characterization of a 64 pixel metallic magnetic calorimeter array with integrated, on-chip microwave SQUID multiplexer

NASA Astrophysics Data System (ADS)

Kempf, S.; Wegner, M.; Deeg, L.; Fleischmann, A.; Gastaldo, L.; Herrmann, F.; Richter, D.; Enss, C.

2017-06-01

We report on the design, fabrication and characterization of a 64 pixel metallic magnetic calorimeter array that is read out by an integrated, on-chip microwave SQUID multiplexer. Based on the results of our comprehensive device characterization we refined the state-of-the-art multiplexer model which assumes each associated non-hysteretic rf-SQUID to purely behave as a flux-dependent inductor. In particular, we include the capacitance and the subgap resistance of the Josephson junction as well as screening effects and parasitic mutual couplings between different coils that show up only when a superconducting flux transformer is attached to the SQUID input. Thanks to these modifications, we are able to explain the occurrence of a magnetic flux dependence of the internal quality factor of the microwave resonators as well as to accurately calculate the characteristic multiplexer parameters. When combining the refined multiplexer model with the thermodynamical description of a metallic magnetic calorimeter, we find a reasonable agreement between our measurements and predictions.

Superconducting multiport antenna arrays

NASA Astrophysics Data System (ADS)

Chaloupka, H.

1993-10-01

Applications of HTS to radiating elements and beam-forming networks of multibeam and/or multifrequency arrays are discussed. This includes radiating elements which meet special requirements with respect to size and frequency response. Realized versions of both a three-port HTS array and a 4 x 4 Butler matrix are presented.

SQUID (superconducting quantum interference device) arrays for simultaneous magnetic measurements: Calibration and source localization performance

NASA Astrophysics Data System (ADS)

Kaufman, Lloyd; Williamson, Samuel J.; Costaribeiro, P.

1988-02-01

Recently developed small arrays of SQUID-based magnetic sensors can, if appropriately placed, locate the position of a confined biomagnetic source without moving the array. The authors present a technique with a relative accuracy of about 2 percent for calibrating such sensors having detection coils with the geometry of a second-order gradiometer. The effects of calibration error and magnetic noise on the accuracy of locating an equivalent current dipole source in the human brain are investigated for 5- and 7-sensor probes and for a pair of 7-sensor probes. With a noise level of 5 percent of peak signal, uncertainties of about 20 percent in source strength and depth for a 5-sensor probe are reduced to 8 percent for a pair of 7-sensor probes, and uncertainties of about 15 mm in lateral position are reduced to 1 mm, for the configuration considered.

Simulated bi-SQUID Arrays Performing Direction Finding

DTIC Science & Technology

2015-09-01

First, we applied the multiple signal classification ( MUSIC ) algorithm on linearly polarized signals. We included multiple signals in the output...both of the same frequency and different fre- quencies. Next, we explored a modified MUSIC algorithm called dimensionality reduction MUSIC (DR- MUSIC ... MUSIC algorithm is able to determine the AoA from the simulated SQUID data for linearly polarized signals. The MUSIC algorithm could accurately find

Microwave SQUID Multiplexer for the Readout of Metallic Magnetic Calorimeters

NASA Astrophysics Data System (ADS)

Kempf, S.; Gastaldo, L.; Fleischmann, A.; Enss, C.

2014-06-01

We have realized a frequency-domain multiplexing technique for the readout of large metallic magnetic calorimeter detector arrays. It is based on non-hysteretic single-junction SQUIDs and allows for a simultaneous readout of hundreds or thousands of detectors by using a single cryogenic high electron mobility transistor amplifier and two coaxial cables that are routed from room-temperature to the detector array. We discuss the working principle of the multiplexer and present details about our prototype multiplexer design. We show that fabricated devices are fully operational and that characteristic SQUID parameters such as the input sensitivity of the SQUID or the resonance frequency of the readout circuit can be predicted with confidence. Our best device so far has shown a magnetic flux white noise level of 1.4 m which can in future be reduced by an optimization of the fabrication processes as well as an improved microwave readout system.

Performance of a novel SQUID-based superconducting imaging-surface magnetoencephalography system

NASA Astrophysics Data System (ADS)

Kraus, R. H.; Volegov, P.; Maharajh, K.; Espy, M. A.; Matlashov, A. N.; Flynn, E. R.

2002-03-01

Performance for a recently completed whole-head magnetoencephalography system using a superconducting imaging surface (SIS) surrounding an array of 150 SQUID magnetometers is reported. The helmet-like SIS is hemispherical in shape with a brim. Conceptually, the SIS images nearby sources onto the SQUIDs while shielding sensors from distant “noise” sources. A finite element method (FEM) description using the as-built geometry was developed to describe the SIS effect on source fields by imposing B⊥( surface)=0 . Sensors consist of 8×8 mm 2 SQUID magnetometers with 0.84 nT/ Φ0 sensitivity and <3 fT/ Hz noise. A series of phantom experiments to verify system efficacy have been completed. Simple dry-wire phantoms were used to eliminate model dependence from our results. Phantom coils were distributed throughout the volume encompassed by the array with a variety of orientations. Each phantom coil was precisely machined and located to better than 25 μm and 10 mRad accuracy. Excellent agreement between model-calculated and measured magnetic field distributions of all phantom coil positions and orientations was found. Good agreement was found between modeled and measured shielding of the SQUIDs from sources external to the array showing significant frequency-independent shielding. Phantom localization precision was better than 0.5 mm at all locations with a mean of better than 0.3 mm.

Simultaneous readout of 128 X-ray and gamma-ray transition-edge microcalorimeters using microwave SQUID multiplexing

NASA Astrophysics Data System (ADS)

Mates, J. A. B.; Becker, D. T.; Bennett, D. A.; Dober, B. J.; Gard, J. D.; Hays-Wehle, J. P.; Fowler, J. W.; Hilton, G. C.; Reintsema, C. D.; Schmidt, D. R.; Swetz, D. S.; Vale, L. R.; Ullom, J. N.

2017-08-01

The number of elements in most cryogenic sensor arrays is limited by the technology available to multiplex signals from the arrays into a smaller number of wires and readout amplifiers. The largest demonstrated arrays of transition-edge sensor (TES) microcalorimeters contain roughly 250 detectors and use time-division multiplexing with Superconducting Quantum Interference Devices (SQUIDs). The bandwidth limits of this technology constrain the number of sensors per amplifier chain, a quantity known as the multiplexing factor, to several 10s. With microwave SQUID multiplexing, we can expand the readout bandwidth and enable much larger multiplexing factors. While microwave SQUID multiplexing of TES microcalorimeters has been previously demonstrated with small numbers of detectors, we now present a fully scalable demonstration in which 128 TES detectors are read out on a single pair of coaxial cables.

SiGe Integrated Circuit Developments for SQUID/TES Readout

NASA Astrophysics Data System (ADS)

Prêle, D.; Voisin, F.; Beillimaz, C.; Chen, S.; Piat, M.; Goldwurm, A.; Laurent, P.

2018-03-01

SiGe integrated circuits dedicated to the readout of superconducting bolometer arrays for astrophysics have been developed since more than 10 years at APC. Whether for Cosmic Microwave Background (CMB) observations with the QUBIC ground-based experiment (Aumont et al. in astro-ph.IM, 2016. arXiv:1609.04372) or for the Hot and Energetic Universe science theme with the X-IFU instrument on-board of the ATHENA space mission (Barret et al. in SPIE 9905, space telescopes & instrumentation 2016: UV to γ Ray, 2016. https://doi.org/10.1117/12.2232432), several kinds of Transition Edge Sensor (TES) (Irwin and Hilton, in ENSS (ed) Cryogenic particle detection, Springer, Berlin, 2005) arrays have been investigated. To readout such superconducting detector arrays, we use time or frequency domain multiplexers (TDM, FDM) (Prêle in JINST 10:C08015, 2016. https://doi.org/10.1088/1748-0221/10/08/C08015) with Superconducting QUantum Interference Devices (SQUID). In addition to the SQUID devices, low-noise biasing and amplification are needed. These last functions can be obtained by using BiCMOS SiGe technology in an Application Specific Integrated Circuit (ASIC). ASIC technology allows integration of highly optimised circuits specifically designed for a unique application. Moreover, we could reach very low-noise and wide band amplification using SiGe bipolar transistor either at room or cryogenic temperatures (Cressler in J Phys IV 04(C6):C6-101, 1994. https://doi.org/10.1051/jp4:1994616). This paper discusses the use of SiGe integrated circuits for SQUID/TES readout and gives an update of the last developments dedicated to the QUBIC telescope and to the X-IFU instrument. Both ASIC called SQmux128 and AwaXe are described showing the interest of such SiGe technology for SQUID multiplexer controls.

TES Detector Noise Limited Readout Using SQUID Multiplexers

NASA Technical Reports Server (NTRS)

Staguhn, J. G.; Benford, D. J.; Chervenak, J. A.; Khan, S. A.; Moseley, S. H.; Shafer, R. A.; Deiker, S.; Grossman, E. N.; Hilton, G. C.; Irwin, K. D.

2004-01-01

The availability of superconducting Transition Edge Sensors (TES) with large numbers of individual detector pixels requires multiplexers for efficient readout. The use of multiplexers reduces the number of wires needed between the cryogenic electronics and the room temperature electronics and cuts the number of required cryogenic amplifiers. We are using an 8 channel SQUID multiplexer to read out one-dimensional TES arrays which are used for submillimeter astronomical observations. We present results from test measurements which show that the low noise level of the SQUID multiplexers allows accurate measurements of the TES Johnson noise, and that in operation, the readout noise is dominated by the detector noise. Multiplexers for large number of channels require a large bandwidth for the multiplexed readout signal. We discuss the resulting implications for the noise performance of these multiplexers which will be used for the readout of two dimensional TES arrays in next generation instruments.

Improved Readout Scheme for SQUID-Based Thermometry

NASA Technical Reports Server (NTRS)

Penanen, Konstantin

2007-01-01

An improved readout scheme has been proposed for high-resolution thermometers, (HRTs) based on the use of superconducting quantum interference devices (SQUIDs) to measure temperature- dependent magnetic susceptibilities. The proposed scheme would eliminate counting ambiguities that arise in the conventional scheme, while maintaining the superior magnetic-flux sensitivity of the conventional scheme. The proposed scheme is expected to be especially beneficial for HRT-based temperature control of multiplexed SQUIDbased bolometer sensor arrays. SQUID-based HRTs have become standard for measuring and controlling temperatures in the sub-nano-Kelvin temperature range in a broad range of low-temperature scientific and engineering applications. A typical SQUIDbased HRT that utilizes the conventional scheme includes a coil wound on a core made of a material that has temperature- dependent magnetic susceptibility in the temperature range of interest. The core and the coil are placed in a DC magnetic field provided either by a permanent magnet or as magnetic flux inside a superconducting outer wall. The aforementioned coil is connected to an input coil of a SQUID. Changes in temperature lead to changes in the susceptibility of the core and to changes in the magnetic flux detected by the SQUID. The SQUID readout instrumentation is capable of measuring magnetic-flux changes that correspond to temperature changes down to a noise limit .0.1 nK/Hz1/2. When the flux exceeds a few fundamental flux units, which typically corresponds to a temperature of .100 nK, the SQUID is reset. The temperature range can be greatly expanded if the reset events are carefully tracked and counted, either by a computer running appropriate software or by a dedicated piece of hardware.

Ultra-Low Field SQUID-NMR using LN2 Cooled Cu Polarizing Field coil

NASA Astrophysics Data System (ADS)

Demachi, K.; Kawagoe, S.; Ariyoshi, S.; Tanaka, S.

2017-07-01

We are developing an Ultra-Low Field (ULF) Magnetic Resonance Imaging (MRI) system using a High-Temperature Superconductor superconducting quantum interference device (HTS rf-SQUID) for food inspection. The advantages of the ULF-NMR (Nuclear Magnetic Resonance) / MRI as compared with a conventional high field MRI are that they are compact and of low cost. In this study, we developed a ULF SQUID-NMR system using a polarizing coil to measure fat of which relaxation time T1 is shorter. The handmade polarizing coil was cooled by liquid nitrogen to reduce the resistance and accordingly increase the allowable current. The measured decay time of the polarizing field was 40 ms. The measurement system consisted of the liquid nitrogen cooled polarizing coil, a SQUID, a Cu wound flux transformer, a measurement field coil for the field of 47 μT, and an AC pulse coil for a 90°pulse field. The NMR measurements were performed in a magnetically shielded room to reduce the environmental magnetic field. The size of the sample was ϕ35 mm × L80 mm. After applying a polarizing field and a 90°pulse, an NMR signal was detected by the SQUID through the flux transformer. As a result, the NMR spectra of fat samples were obtained at 2.0 kHz corresponding to the measurement field Bm of 47 μT. The T1 relaxation time of the mineral oil measured in Bm was 45 ms. These results suggested that the ULF-NMR/MRI system has potential for food inspection.

Measuring MEG closer to the brain: Performance of on-scalp sensor arrays

PubMed Central

Iivanainen, Joonas; Stenroos, Matti; Parkkonen, Lauri

2017-01-01

Optically-pumped magnetometers (OPMs) have recently reached sensitivity levels required for magnetoencephalography (MEG). OPMs do not need cryogenics and can thus be placed within millimetres from the scalp into an array that adapts to the invidual head size and shape, thereby reducing the distance from cortical sources to the sensors. Here, we quantified the improvement in recording MEG with hypothetical on-scalp OPM arrays compared to a 306-channel state-of-the-art SQUID array (102 magnetometers and 204 planar gradiometers). We simulated OPM arrays that measured either normal (nOPM; 102 sensors), tangential (tOPM; 204 sensors), or all components (aOPM; 306 sensors) of the magnetic field. We built forward models based on magnetic resonance images of 10 adult heads; we employed a three-compartment boundary element model and distributed current dipoles evenly across the cortical mantle. Compared to the SQUID magnetometers, nOPM and tOPM yielded 7.5 and 5.3 times higher signal power, while the correlations between the field patterns of source dipoles were reduced by factors of 2.8 and 3.6, respectively. Values of the field-pattern correlations were similar across nOPM, tOPM and SQUID gradiometers. Volume currents reduced the signals of primary currents on average by 10%, 72% and 15% in nOPM, tOPM and SQUID magnetometers, respectively. The information capacities of the OPM arrays were clearly higher than that of the SQUID array. The dipole-localization accuracies of the arrays were similar while the minimum-norm-based point-spread functions were on average 2.4 and 2.5 times more spread for the SQUID array compared to nOPM and tOPM arrays, respectively. PMID:28007515

Onshore-offshore movement of jumbo squid (Dosidicus gigas) on the continental shelf

NASA Astrophysics Data System (ADS)

Stewart, Julia S.; Gilly, William F.; Field, John C.; Payne, John C.

2013-10-01

Jumbo squid (Dosidicus gigas) have greatly extended their range in the California Current System, where they forage on a variety of ecologically and economically important species that inhabit both coastal and offshore mesopelagic regions. Swimming abilities and behavior are important factors in assessing the impacts of this range expansion, particularly in regard to foraging in conjunction with onshore-offshore movement over the continental shelf. Here we describe a study of horizontal movements by jumbo squid along and across the continental shelf off Washington, USA, using acoustic tags in association with the Census of Marine Life's Pacific Ocean Shelf Tracking Program (POST) receiver arrays. We detected frequent movements along the shelf break, movement onto the shelf at night, and no evidence of movement as a cohesive school. Our results demonstrate feasibility of using acoustic tags and arrays to document horizontal movements of jumbo squid along and across the continental shelf. This is important in order to determine how those movements overlap with those of other ecologically and commercially important fish species.

Design, development and calibration of HTS wire based LOX level sensor probe

NASA Astrophysics Data System (ADS)

Karunanithi, R.; Jacob, S.; Nadig, D. S.; Prasad, M. V. N.; Gour, A. S.; Gowthaman, M.; Deekshith, P.; Shrivastava, V.

2014-01-01

For space applications, the weight of the liquid level sensors are of major concern as they affect the payload fraction and hence the cost. An attempt is made to design and test a light weight High Temperature Superconductor (HTS) wire based liquid level sensor for Liquid Oxygen (LOX) tank used in the cryostage of the spacecraft. The total resistance value measured of the HTS wire is inversely proportional to the liquid level. A HTS wire (SF12100) of 12mm width and 2.76m length without copper stabilizer has been used in the level sensor. The developed HTS wire based LOX level sensor is calibrated against a discrete diode array type level sensor. Liquid Nitrogen (LN2) and LOX has been used as cryogenic fluid for the calibration purpose. The automatic data logging for the system has been done using LabVIEW11. The net weight of the developed sensor is less than 1 kg.

Low noise SQUIDs

NASA Astrophysics Data System (ADS)

de Waal, V. J.

1983-02-01

The present investigation deals with the design, fabrication, and limitations of very sensitive SQUID (Superconducting Quantum Interference Device) magnetometers. The SQUID magnetometer is based on a utilization of the Josephson effect. A description of the theoretical background is provided, and high performance DC SQUIDs with submicron niobium Josephson junctions are discussed, taking into account design considerations, fabrication, junction characterization, the performance of the SQUID and input coil, and the gradiometer performance. The simulation and optimization of a DC SQUID with finite capacitance is considered, giving attention to the implementation of a simulation procedure on a hybrid computer.

Static and dynamic stability of the guidance force in a side-suspended HTS maglev system

NASA Astrophysics Data System (ADS)

Zhou, Dajin; Cui, Chenyu; Zhao, Lifeng; Zhang, Yong; Wang, Xiqing; Zhao, Yong

2017-02-01

The static and dynamic stability of the guidance force in a side-suspended HTS-PMG (permanent magnetic guideway) system were studied theoretically and experimentally. It is found that there are two types of guidance force that exist in the HTS-PMG system, which are sensitive to the levitation gap and the arrangement of YBCO bulks around the central axis of the PMG. An optimized YBCO array was used to stabilize the system, which enabled a side-suspended HTS-PMG maglev vehicle to run stably at 102 km h-1 on a circular test track with 6.5 m in diameter.

Multiplexing of Hot-Electron Nanobolometers Using Microwave SQUIDs

NASA Technical Reports Server (NTRS)

Karasik, Boris S.; Day, Peter K.; Kawamura, Jonathan H.; Bumble, Bruce; LeDuc, Henry G.

2009-01-01

We have obtained the first data on the multiplexed operation of titanium hot-electron bolometers (HEB). Because of their low thermal conductance and small electron heat capacity nanobolometers are particularly interesting as sensors for far-infrared spectroscopy and mid- and near-IR calorimetry. However, the short time constant of these devices (approximately microseconds at 300-400 mK) makes time domain or audio-frequency domain multiplexing impractical. The Microwave SQUID (MSQUID) approach pursued in this work uses dc SQUIDs coupled to X-band microresonators which are, in turn, coupled to a transmission line. We used a 4-element array of Ti HEBs operated at 415 mK in a He3 dewar with an optical fiber access. The microwave signal exhibited 10-MHz wide resonances at individual MSQUD frequencies between 9 GHz and 10 GHz. The resonance depth is modulated by the current through the bolometer via a change of the SQUID flux state. The transmitted signal was amplified by a cryogenic amplifier and downconverted to baseband using an IQ mixer. A 1-dB per ??/2 responsivity was sufficient for keeping the system noise at the level of 2 pA/Hz1/2. This is more than an order of magnitude smaller than phonon noise in the HEB. The devices were able to detect single near- IR photons (1550 nm) with a time constant of 3.5 ?s. Follow-on work will scale the array to larger size and will address the microwave frequency signal generation and processing using a digital transceiver.

Nonlinear Behavior of a Shim Coil in an LTS/HTS NMR Magnet With an HTS Insert Comprising Double-Pancake HTS-Tape Coils

PubMed Central

Hahn, Seung-yong; Ahn, Min Cheol; Bascuñán, Juan; Yao, Weijun; Iwasa, Yukikazu

2010-01-01

This paper reports results, experimental and analytical, of the nonlinear behavior of a shim coil in the presence of an HTS coil assembled with double-pancake (DP) HTS-tape coils. The experimental results are from: 1) operation of a 700 MHz LTS/HTS NMR magnet (LH700) consisting of a 600 MHz LTS NMR magnet (L600) equipped with superconducting shim coils and a 100 MHz DP-assembled HTS insert (H100) and; 2) an experiment with a room-temperature (RT) Z1 shim coil coupled to a 50 MHz DP-as-sembled HTS insert (H50). A field mapping theory with a harmonic analysis is applied to interpret both results. Based on experimental results and analyses, we conclude that the screening-current-induced field (SCF) generated by a DP-assembled HTS insert is primarily responsible for the nonlinear behavior, including strength degradation, of a shim coil. PMID:20383282

Squid rocket science: How squid launch into air

NASA Astrophysics Data System (ADS)

O'Dor, Ron; Stewart, Julia; Gilly, William; Payne, John; Borges, Teresa Cerveira; Thys, Tierney

2013-10-01

Squid not only swim, they can also fly like rockets, accelerating through the air by forcefully expelling water out of their mantles. Using available lab and field data from four squid species, Sthenoteuthis pteropus, Dosidicus gigas, Illex illecebrosus and Loligo opalescens, including sixteen remarkable photographs of flying S. pteropus off the coast of Brazil, we compared the cost of transport in both water and air and discussed methods of maximizing power output through funnel and mantle constriction. Additionally we found that fin flaps develop at approximately the same size range as flight behaviors in these squids, consistent with previous hypotheses that flaps could function as ailerons whilst aloft. S. pteropus acceleration in air (265 body lengths [BL]/s2; 24.5m/s2) was found to exceed that in water (79BL/s2) three-fold based on estimated mantle length from still photos. Velocities in air (37BL/s; 3.4m/s) exceed those in water (11BL/s) almost four-fold. Given the obvious advantages of this extreme mode of transport, squid flight may in fact be more common than previously thought and potentially employed to reduce migration cost in addition to predation avoidance. Clearly squid flight, the role of fin flaps and funnel, and the energetic benefits are worthy of extended investigation.

Novel Multiplexing Technique for Detector and Mixer Arrays

NASA Technical Reports Server (NTRS)

Karasik, Boris S.; McGrath, William R.

2001-01-01

Future submillimeter and far-infrared space telescopes will require large-format (many 1000's of elements) imaging detector arrays to perform state-of-the-art astronomical observations. A crucial issue related to a focal plane array is a readout scheme which is compatible with large numbers of cryogenically-cooled (typically < 1 K) detectors elements. When the number of elements becomes of the order of thousands, the physical layout for individual readout amplifiers becomes nearly impossible to realize for practical systems. Another important concern is the large number of wires leading to a 0.1-0.3 K platform. In the case of superconducting transition edge sensors (TES), a scheme for time-division multiplexing of SQUID read-out amplifiers has been recently demonstrated. In this scheme the number of SQUIDs is equal to the number (N) of the detectors, but only one SQUID is turned on at a time. The SQUIDs are connected in series in each column of the array, so the number of wires leading to the amplifiers can be reduced, but it is still of the order of N. Another approach uses a frequency domain multiplexing scheme of the bolometer array. The bolometers are biased with ac currents whose frequencies are individual for each element and are much higher than the bolometer bandwidth. The output signals are connected in series in a summing loop which is coupled to a single SQUID amplifier. The total number of channels depends on the ratio between the SQUID bandwidth and the bolometer bandwidth and can be at least 100 according to the authors. An important concern about this technique is a contribution of the out-of-band Johnson noise which multiplies by factor N(exp 1/2) for each frequency channel. We propose a novel solution for large format arrays based on the Hadamard transform coding technique which requires only one amplifier to read out the entire array of potentially many 1000's of elements and uses approximately 10 wires between the cold stage and room temperature

Squids old and young: Scale-free design for a simple billboard

NASA Astrophysics Data System (ADS)

Packard, Andrew

2011-03-01

Squids employ a large range of brightness-contrast spatial frequencies in their camouflage and signalling displays. The 'billboard' of coloured elements ('spots'=chromatophore organs) in the skin is built autopoietically-probably by lateral inhibitory processes-and enlarges as much as 10,000-fold during development. The resulting two-dimensional array is a fractal-like colour/size hierarchy lying in several layers of a multilayered network. Dynamic control of the array by muscles and nerves produces patterns that recall 'half-tone' processing (cf. ink-jet printer). In the more sophisticated (loliginid) squids, patterns also combine 'continuous tones' (cf. dye-sublimation printer). Physiologists and engineers can exploit the natural colour-coding of the integument to understand nerve and muscle system dynamics, examined here at the level of the ensemble. Integrative functions of the whole (H) are analysed in terms of the power spectrum within and between ensembles and of spontaneous waves travelling through the billboard. Video material may be obtained from the author at the above address.

Failure Analysis of CCD Image Sensors Using SQUID and GMR Magnetic Current Imaging

NASA Technical Reports Server (NTRS)

Felt, Frederick S.

2005-01-01

During electrical testing of a Full Field CCD Image Senor, electrical shorts were detected on three of six devices. These failures occurred after the parts were soldered to the PCB. Failure analysis was performed to determine the cause and locations of these failures on the devices. After removing the fiber optic faceplate, optical inspection was performed on the CCDs to understand the design and package layout. Optical inspection revealed that the device had a light shield ringing the CCD array. This structure complicated the failure analysis. Alternate methods of analysis were considered, including liquid crystal, light and thermal emission, LT/A, TT/A SQUID, and MP. Of these, SQUID and MP techniques were pursued for further analysis. Also magnetoresistive current imaging technology is discussed and compared to SQUID.

A study on the required performance of a 2G HTS wire for HTS wind power generators

NASA Astrophysics Data System (ADS)

Sung, Hae-Jin; Park, Minwon; Go, Byeong-Soo; Yu, In-Keun

2016-05-01

YBCO or REBCO coated conductor (2G) materials are developed for their superior performance at high magnetic field and temperature. Power system applications based on high temperature superconducting (HTS) 2G wire technology are attracting attention, including large-scale wind power generators. In particular, to solve problems associated with the foundations and mechanical structure of offshore wind turbines, due to the large diameter and heavy weight of the generator, an HTS generator is suggested as one of the key technologies. Many researchers have tried to develop feasible large-scale HTS wind power generator technologies. In this paper, a study on the required performance of a 2G HTS wire for large-scale wind power generators is discussed. A 12 MW class large-scale wind turbine and an HTS generator are designed using 2G HTS wire. The total length of the 2G HTS wire for the 12 MW HTS generator is estimated, and the essential prerequisites of the 2G HTS wire based generator are described. The magnetic field distributions of a pole module are illustrated, and the mechanical stress and strain of the pole module are analysed. Finally, a reasonable price for 2G HTS wire for commercialization of the HTS generator is suggested, reflecting the results of electromagnetic and mechanical analyses of the generator.

Enhancements to a Superconducting Quantum Interference Device (SQUID) Multiplexer Readout and Control System

NASA Technical Reports Server (NTRS)

Forgione, J.; Benford, D. J.; Buchanan, E. D.; Moseley, S. H.; Rebar, J.; Shafer, R. A.

2004-01-01

Far-infrared detector arrays such as the 16x32 superconducting bolometer array for the SAFIRE instrument (flying on the SOFIA airborne observatory) require systems of readout and control electronics to provide translation between a user-driven, digital PC and the cold, analog world of the cryogenic detector. In 2001, the National Institute of Standards and Technology (NIST) developed their Mark III electronics for purposes of control and readout of their 1x32 SQUID Multiplexer chips. We at NASA s Goddard Space Flight Center acquired a Mark 111 system and subsequently designed upgrades to suit our and our collaborators purposes. We developed an arbitrary, programmable multiplexing system that allows the user to cycle through rows in a SQUID array in an infinite number of combinations. We provided hooks in the Mark III system to allow readout of signals from outside the Mark 111 system, such as telescope status information. Finally, we augmented the heart of the system with a new feedback algorithm implementation, flexible diagnostic tools, and informative telemetry.

Enhancements to a superconducting quantum interference device (SQUID) multiplexer readout and control system

NASA Astrophysics Data System (ADS)

Forgione, Joshua B.; Benford, Dominic J.; Buchanan, Ernest D.; Moseley, S. H., Jr.; Rebar, Joyce; Shafer, Richard A.

2004-10-01

Far-infrared detector arrays such as the 16x32 superconducting bolometer array for the SAFIRE instrument (flying on the SOFIA airborne observatory) require systems of readout and control electronics to provide translation between a user-driven, digital PC and the cold, analog world of the cryogenic detector. In 2001, the National Institute of Standards and Technology (NIST) developed their Mark III electronics for purposes of control and readout of their 1x32 SQUID Multiplexer chips. We at NASA's Goddard Space Flight Center acquired a Mark III system and subsequently designed upgrades to suit our and our collaborators' purposes. We developed an arbitrary, programmable multiplexing system that allows the user to cycle through rows in a SQUID array in an infinite number of combinations. We provided 'hooks' in the Mark III system to allow readout of signals from outside the Mark III system, such as telescope status information. Finally, we augmented the heart of the system with a new feedback algorithm implementation, flexible diagnostic tools, and informative telemetry.

Nonlinear vibration behaviors of high-Tc superconducting bulks in an applied permanent magnetic array field

NASA Astrophysics Data System (ADS)

Li, Jipeng; Li, Haitao; Zheng, Jun; Zheng, Botian; Huang, Huan; Deng, Zigang

2017-06-01

The nonlinear vibration of high temperature superconducting (HTS) bulks in an applied permanent magnetic array (Halbach array) field, as a precondition for commercial application to HTS maglev train and HTS bearing, is systematically investigated. This article reports the actual vibration rules of HTS bulks from three aspects. First, we propose a new numerical model to simplify the calculation of levitation force. This model could provide precise simulations, especially the estimation of eigenfrequency. Second, an approximate analytic solution of the vibration of the HTS bulks is obtained by using the method of harmonic balance. Finally, to verify the results mentioned above, we measure the vertical vibration acceleration signals of an HTS maglev model, consisting of eight YBaCuO bulks, oscillating freely above a Halbach array with large displacement excitation. Higher order harmonic components, which indicate the nonlinear vibration phenomenon, are detected in the responses. All the three results are compared and agreed well with each other. This study combines the experimental and theoretical analyses and provides a deep understanding of the physical phenomenon of the nonlinear vibration and is meaningful for the vibration control of the relevant applications.

Reflective HTS switch

DOEpatents

Martens, Jon S.; Hietala, Vincent M.; Hohenwarter, Gert K. G.

1994-01-01

A HTS switch includes a HTS conductor for providing a superconducting path for an electrical signal and an serpentine wire actuator for controllably heating a portion of the conductor sufficiently to cause that portion to have normal, and not superconducting, resistivity. Mass of the portion is reduced to decrease switching time.

First Tests of Prototype SCUBA-2 Superconducting Bolometer Array

NASA Astrophysics Data System (ADS)

Woodcraft, Adam L.; Ade, Peter A. R.; Bintley, Dan; Hunt, Cynthia L.; Sudiwala, Rashmi V.; Hilton, Gene C.; Irwin, Kent D.; Reintsema, Carl D.; Audley, Michael D.; Holland, Wayne S.; MacIntosh, Mike

2006-09-01

We present results of the first tests on a 1280 pixel superconducting bolometer array, a prototype for SCUBA-2, a sub-mm camera being built for the James Clerk Maxwell Telescope in Hawaii. The bolometers are TES (transition edge sensor) detectors; these take advantage of the large variation of resistance with temperature through the superconducting transition. To keep the number of wires reasonable, a multiplexed read-out is used. Each pixel is read out through an individual DC SQUID; room temperature electronics switch between rows in the array by biasing the appropriate SQUIDs in turn. Arrays of 100 SQUIDs in series for each column then amplify the output. Unlike previous TES arrays, the multiplexing elements are located beneath each pixel, making large arrays possible, but construction more challenging. The detectors are constructed from Mo/Cu bi-layers; this technique enables the transition temperature to be tuned using the proximity effect by choosing the thickness of the normal and superconducting materials. To achieve the required performance, the detectors are operated at a temperature of approximately 120 mK. We describe the results of a basic characterisation of the array, demonstrating that it is fully operational, and give the results of signal to noise measurements.

NanoSQUIDs: Basics & recent advances

NASA Astrophysics Data System (ADS)

José Martínez-Pérez, Maria; Koelle, Dieter

2017-08-01

Superconducting Quantum Interference Devices (SQUIDs) are one of the most popular devices in superconducting electronics. They combine the Josephson effect with the quantization of magnetic flux in superconductors. This gives rise to one of the most beautiful manifestations of macroscopic quantum coherence in the solid state. In addition, SQUIDs are extremely sensitive sensors allowing us to transduce magnetic flux into measurable electric signals. As a consequence, any physical observable that can be converted into magnetic flux, e.g., current, magnetization, magnetic field or position, becomes easily accessible to SQUID sensors. In the late 1980s it became clear that downsizing the dimensions of SQUIDs to the nanometric scale would encompass an enormous increase of their sensitivity to localized tiny magnetic signals. Indeed, nanoSQUIDs opened the way to the investigation of, e.g., individual magnetic nanoparticles or surface magnetic states with unprecedented sensitivities. The purpose of this chapter is to present a detailed survey of microscopic and nanoscopic SQUID sensors. We will start by discussing the principle of operation of SQUIDs, placing the emphasis on their application as ultrasensitive detectors for small localized magnetic signals. We will continue by reviewing a number of existing devices based on different kinds of Josephson junctions and materials, focusing on their advantages and drawbacks. The last sections are left for applications of nanoSQUIDs in the fields of scanning SQUID microscopy and magnetic particle characterization, placing special stress on the investigation of individual magnetic nanoparticles.

Reflective HTS switch

DOEpatents

Martens, J.S.; Hietala, V.M.; Hohenwarter, G.K.G.

1994-09-27

A HTS (High Temperature Superconductor) switch includes a HTS conductor for providing a superconducting path for an electrical signal and an serpentine wire actuator for controllably heating a portion of the conductor sufficiently to cause that portion to have normal, and not superconducting, resistivity. Mass of the portion is reduced to decrease switching time. 6 figs.

Recent advancements in the SQUID magnetospinogram system

NASA Astrophysics Data System (ADS)

Adachi, Yoshiaki; Kawai, Jun; Haruta, Yasuhiro; Miyamoto, Masakazu; Kawabata, Shigenori; Sekihara, Kensuke; Uehara, Gen

2017-06-01

In this study, a new superconducting quantum interference device (SQUID) biomagnetic measurement system known as magnetospinogram (MSG) is developed. The MSG system is used for observation of a weak magnetic field distribution induced by the neural activity of the spinal cord over the body surface. The current source reconstruction for the observed magnetic field distribution provides noninvasive functional imaging of the spinal cord, which enables medical personnel to diagnose spinal cord diseases more accurately. The MSG system is equipped with a uniquely shaped cryostat and a sensor array of vector-type SQUID gradiometers that are designed to detect the magnetic field from deep sources across a narrow observation area over the body surface of supine subjects. The latest prototype of the MSG system is already applied in clinical studies to develop a diagnosis protocol for spinal cord diseases. Advancements in hardware and software for MSG signal processing and cryogenic components aid in effectively suppressing external magnetic field noise and reducing the cost of liquid helium that act as barriers with respect to the introduction of the MSG system to hospitals. The application of the MSG system is extended to various biomagnetic applications in addition to spinal cord functional imaging given the advantages of the MSG system for investigating deep sources. The study also includes a report on the recent advancements of the SQUID MSG system including its peripheral technologies and wide-spread applications.

Flux trapping in multi-loop SQUIDs and its impact on SQUID-based absolute magnetometry

NASA Astrophysics Data System (ADS)

Schönau, T.; Zakosarenko, V.; Schmelz, M.; Anders, S.; Meyer, H.-G.; Stolz, R.

2018-07-01

The effect of flux trapping on the flux-voltage characteristics of multi-loop SQUID magnetometers was investigated by means of repeated cool-down cycles in a stepwise increased magnetic background field. For a SQUID with N parallel loops, N different flux offsets, each separated by {{{Φ }}}0/N, were observed even in zero magnetic field. These flux offsets further split into a so called fine structure, which can be explained by minor asymmetries in the SQUID design. The observed results are discussed with particular regard to their impact on the previously presented absolute SQUID cascade vector magnetometer.

Design and manufacture of a D-shape coil-based toroid-type HTS DC reactor using 2nd generation HTS wire

NASA Astrophysics Data System (ADS)

Kim, Kwangmin; Go, Byeong-Soo; Sung, Hae-Jin; Park, Hea-chul; Kim, Seokho; Lee, Sangjin; Jin, Yoon-Su; Oh, Yunsang; Park, Minwon; Yu, In-Keun

2014-09-01

This paper describes the design specifications and performance of a real toroid-type high temperature superconducting (HTS) DC reactor. The HTS DC reactor was designed using 2G HTS wires. The HTS coils of the toroid-type DC reactor magnet were made in the form of a D-shape. The target inductance of the HTS DC reactor was 400 mH. The expected operating temperature was under 20 K. The electromagnetic performance of the toroid-type HTS DC reactor magnet was analyzed using the finite element method program. A conduction cooling method was adopted for reactor magnet cooling. Performances of the toroid-type HTS DC reactor were analyzed through experiments conducted under the steady-state and charge conditions. The fundamental design specifications and the data obtained from this research will be applied to the design of a commercial-type HTS DC reactor.

Microwave SQUID Multiplexing of Metallic Magnetic Calorimeters: Status of Multiplexer Performance and Room-Temperature Readout Electronics Development

NASA Astrophysics Data System (ADS)

Wegner, M.; Karcher, N.; Krömer, O.; Richter, D.; Ahrens, F.; Sander, O.; Kempf, S.; Weber, M.; Enss, C.

2018-02-01

To our present best knowledge, microwave SQUID multiplexing (μ MUXing) is the most suitable technique for reading out large-scale low-temperature microcalorimeter arrays that consist of hundreds or thousands of individual pixels which require a large readout bandwidth per pixel. For this reason, the present readout strategy for metallic magnetic calorimeter (MMC) arrays combining an intrinsic fast signal rise time, an excellent energy resolution, a large energy dynamic range, a quantum efficiency close to 100% as well as a highly linear detector response is based on μ MUXing. Within this paper, we summarize the state of the art in MMC μ MUXing and discuss the most recent results. This particularly includes the discussion of the performance of a 64-pixel detector array with integrated, on-chip microwave SQUID multiplexer, the progress in flux ramp modulation of MMCs as well as the status of the development of a software-defined radio-based room-temperature electronics which is specifically optimized for MMC readout.

SQUID magnetometers for low-frequency applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ryhaenen, T.; Seppae, H.; Ilmoniemi, R.

1989-09-01

The authors present a novel formulation for SQUID operation, which enables them to evaluate and compare the sensitivity and applicability of different devices. SQUID magnetometers for low-frequency applications are analyzed, taking into account the coupling circuits and electronics. They discuss nonhysteretic and hysteretic single-junction rf SQUIDs, but the main emphasis is on the dynamics, sensitivity, and coupling considerations of dc-SQUID magnetometers. A short review of current ideas on thin-film, dc-SQUID design presents the problems in coupling and the basic limits of sensitivity. The fabrication technology of tunnel-junction devices is discussed with emphasis on how it limits critical current densities, specificmore » capacitances of junctions, minimum linewidths, conductor separations, etc. Properties of high-temperature superconductors are evaluated on the basis of recently published results on increased flux creep, low density of current carriers, and problems in fabricating reliable junctions. The optimization of electronics for different types of SQUIDs is presented. Finally, the most important low-frequency applications of SQUIDs in biomagnetism, metrology, geomagnetism, and some physics experiments demonstrate the various possibilities that state-of-the-art SQUIDs can provide.« less

Low-noise SQUID

DOEpatents

Dantsker, Eugene; Clarke, John

2000-01-01

The present invention comprises a high-transition-temperature superconducting device having low-magnitude low-frequency noise-characteristics in magnetic fields comprising superconducting films wherein the films have a width that is less than or equal to a critical width, w.sub.C, which depends on an ambient magnetic field. For operation in the Earth's magnetic field, the critical width is about 6 micrometers (.mu.m). When made with film widths of about 4 .mu.m an inventive high transition-temperature, superconducting quantum interference device (SQUID) excluded magnetic flux vortices up to a threshold ambient magnetic field of about 100 microTesla (.mu.T). SQUIDs were fabricated having several different film strip patterns. When the film strip width was kept at about 4 .mu.m, the SQUIDs exhibited essentially no increase in low-frequency noise, even when cooled in static magnetic fields of magnitude up to 100 .mu.T. Furthermore, the mutual inductance between the inventive devices and a seven-turn spiral coil was at least 85% of that for inductive coupling to a conventional SQUID.

Foraging ecology and movement patterns of jumbo squid (Dosidicus gigas) in the California Current System

NASA Astrophysics Data System (ADS)

Field, John C.; Elliger, Carl; Baltz, Ken; Gillespie, Graham E.; Gilly, William F.; Ruiz-Cooley, R. I.; Pearse, Devon; Stewart, Julia S.; Matsubu, William; Walker, William A.

2013-10-01

From 2002 to 2010, the jumbo squid (Dosidicus gigas) has been regularly encountered in large numbers throughout the California Current System (CCS). This species, usually found in subtropical waters, could affect coastal pelagic ecosystems and fisheries as both predator and prey. Neither the abundance of jumbo squid nor the optimal ocean conditions in which they flourish are well known. To understand better the potential impacts of this species on both commercial fisheries and on food-web structure we collected nearly 900 specimens from waters of the CCS, covering over 20° of latitude, over a range of depths and seasons. We used demographic information (size, sex, and maturity state) and analyzed stomach contents using morphological and molecular methods to best understand the foraging ecology of this species in different habitats of the CCS. Squid were found to consume a broad array of prey. Prey in offshore waters generally reflected the forage base reported in previous studies (mainly mesopelagic fishes and squids), whereas in more coastal waters (shelf, shelf break and slope habitats) squid foraged on a much broader mix that included substantial numbers of coastal pelagic fishes (Pacific herring and northern anchovy, as well as osmerids and salmonids in northern waters) and groundfish (Pacific hake, several species of rockfish and flatfish). We propose a seasonal movement pattern, based on size and maturity distributions along with qualitative patterns of presence or absence, and discuss the relevance of both the movement and distribution of jumbo squid over space and time. We find that jumbo squid are a generalist predator, which feeds primarily on small, pelagic or mesopelagic micronekton but also on larger fishes when they are available. We also conclude that interactions with and potential impacts on ecosystems likely vary over space and time, in response to both seasonal movement patterns and highly variable year-to-year abundance of the squid themselves.

Development of transition edge sensors with rf-SQUID based multiplexing system for the HOLMES experiment

NASA Astrophysics Data System (ADS)

Puiu, A.; Becker, D.; Bennett, D.; Faverzani, M.; Ferri, E.; Fowler, J.; Gard, J.; Hays-Wehle, J.; Hilton, G.; Giachero, A.; Maino, M.; Mates, J.; Nucciotti, A.; Schmidt, D.; Swetz, D.; Ullom, J.; Vale, L.

2017-09-01

Measuring the neutrino mass is one the most compelling issue in particle physics. HOLMES is an experiment funded by the European Research Council for a direct measurement of neutrino mass. HOLMES will perform a precise measurement of the end point of the Electron Capture decay spectrum of 163Ho in order to extract information on neutrino mass with a sensitivity as low as 1 eV. HOLMES, in its final configuration will deploy a 1000 pixel array of low temperature microcalorimeters: each calorimeter consists of an absorber, where the Ho atoms will be implanted, coupled to a Transition Edge Sensor thermometer. The detectors will be kept at the working temperature of ˜70 mK using a dilution refrigerator. In order to gather the required 3 × 1013 events in a three year long data taking with a pile up fraction as low as 10-4, detectors must fulfill rather high speed and resolution requirements, i.e. 10 µs rise time and 4 eV resolution. To ensure such performances with an efficient read out technique for very large detectors array kept at low temperature inside a cryostat is no trivial matter: at the moment, the most appealing read out technique applicable to large arrays of Transition Edge Sensors is rf-SQUID multiplexing. It is based on the use of rf-SQUIDs as input devices with flux ramp modulation for linearisation purposes; the rf-SQUID is then coupled to a super-conductive λ/4-wave resonator in the GHz range, and the modulated signal is finally read out using the homodyne technique.

ToxCast HTS Assay Development and Retrofitting: Strategies ...

EPA Pesticide Factsheets

A presentation to EC JRC partners on new ToxCast HTS assay methods and strategies to address current limitations to HTS methods Slide presentation to EC JRC partners on new ToxCast HTS assay methods and strategies to address current limitations to HTS methods.

The Multiplexed SQUID TES array at Ninety Gigahertz (MUSTANG)

NASA Astrophysics Data System (ADS)

Korngut, Phillip M.

The Multiplexed SQUID/TES Array at Ninety Gigahertz (MUSTANG) is a bolometric continuum imaging camera designed to operate at the Gregorian focus of the 100 m Green Bank Telescope (GBT) in Pocahontas county, West Virginia. The combination of the GBT's large collecting area and the 8 x 8 array of transition edge sensors at the heart of MUSTANG allows for deep imaging at 10'' resolution at 90 GHz. The MUSTANG receiver is now a facility instrument of the National Radio Astronomy Observatory available to the general astronomical community. The 3.3 mm continuum passband is useful to access a large range of Galactic and extra-Galactic astrophysics. Sources with synchrotron, free-free and thermal blackbody emission can be detected at 3.3 mm. Of particular interest is the Sunyaev Zel'dovich effect in clusters of galaxies, which arises from the inverse Compton scattering of CMB photons off hot electrons in the intra-cluster medium. In the MUSTANG band, the effect is observationally manifested as an artificial decrement in power on the sky in the direction of the cluster. There have been many experiments in the past two decades dedicated to measurements of the SZE, however, nearly all of them were accomplished with angular resolution larger than ˜ 1'. The massive primary of the GBT enables measurements of the SZE on 10'' scales. This provides a new technique to map pressure substructure in the plasma atmospheres of merging clusters of galaxies. By analyzing MUSTANG data along side X-ray data, spatially resolved measurements of the temperature, density and pressure of the ICM can be performed which can be used to infer the physics governing major mergers. This thesis details the design, commissioning and operation of the various components which comprise the MUSTANG receiver. This includes the sub-kelvin cryogenic cooling, the time domain multiplexed readout electronics and the array of transition edge sensor bolometers. Laboratory characterization of the detector array is

Applications of Josephson Junction SQUIDs (Superconducting Quantum Interference Device) and Arrays.

DTIC Science & Technology

1982-11-01

Research, Cntract 7he transient respose is doinated by o NO. 00014-61-C-0615. and Wj. Figure 2 shows the time evolution of e a:d e M for owI, 0-1 and 5...connect a dc S 0UID "Shunted Josephson Tunel Junctions- if gh transmitter with another dc SQU D receiver by a Frequency, Self -Pvmd L Nise lifiers...resistive SQUID WVO incidentally to their self -puVzed Josepson perametric2 mplifier. Using a SQJID with 6 -2. ZmpHi, r-3xlO . and a in matching

History of HTS motor development at Reliance Electric

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schiferl, R.

1994-07-29

A review of the High Temperature Superconducting (HTS) motor development program at Reliance Electric is presented. The project was initiated in 1987 by EPRI to investigate the use of high temperature superconducting materials in electric motors. Liquid nitrogen was proposed as the HTS winding coolant. The ultimate goal, motivation, motor type and HTS wire requirements as well as the program milestones are outlined. It was concluded that the HTS motor development has paralleled wire development; progress continues toward the goal of large horsepower HTS motors for commercial applications; the team is well on the way toward completing the design ofmore » a 125 hp, 1800 rpm motor with HTS coils cooled to 20 to 40 K; and the program is a vital step in the development of HTS motors.« less

Far infrared through millimeter backshort-under-grid arrays

NASA Astrophysics Data System (ADS)

Allen, Christine A.; Abrahams, John; Benford, Dominic J.; Chervenak, James A.; Chuss, David T.; Staguhn, Johannes G.; Miller, Timothy M.; Moseley, S. Harvey; Wollack, Edward J.

2006-06-01

We are developing a large-format, versatile, bolometer array for a wide range of infrared through millimeter astronomical applications. The array design consists of three key components - superconducting transition edge sensor bolometer arrays, quarter-wave reflective backshort grids, and Superconducting Quantum Interference Device (SQUID) multiplexer readouts. The detector array is a filled, square grid of bolometers with superconducting sensors. The backshort arrays are fabricated separately and are positioned in the etch cavities behind the detector grid. The grids have unique three-dimensional interlocking features micromachined into the walls for positioning and mechanical stability. The ultimate goal of the program is to produce large-format arrays with background-limited sensitivity, suitable for a wide range of wavelengths and applications. Large-format (kilopixel) arrays will be directly indium bump bonded to a SQUID multiplexer circuit. We have produced and tested 8×8 arrays of 1 mm detectors to demonstrate proof of concept. 8×16 arrays of 2 mm detectors are being produced for a new Goddard Space Flight Center instrument. We have also produced models of a kilopixel detector grid and dummy multiplexer chip for bump bonding development. We present detector design overview, several unique fabrication highlights, and assembly technologies.

The Stationary SQUID

NASA Astrophysics Data System (ADS)

Berger, Jorge

2018-06-01

In the customary mode of operation of a SQUID, the electromagnetic field in the SQUID is an oscillatory function of time. In this situation, electromagnetic radiation is emitted and couples to the sample. This is a back action that can alter the state that we intend to measure. A circuit that could perform as a stationary SQUID consists of a loop of superconducting material that encloses the magnetic flux, connected to a superconducting and to a normal electrode. This circuit does not contain Josephson junctions, or any other miniature feature. We study the evolution of the order parameter and of the electrochemical potential in this circuit; they converge to a stationary regime, and the voltage between the electrodes depends on the enclosed flux. We obtain expressions for the power dissipation and for the heat transported by the electric current; the validity of these expressions does not rely on a particular evolution model for the order parameter. We evaluate the influence of fluctuations. For a SQUID perimeter of the order of 1μ m and temperature 0.9T_c, we obtain a flux resolution of the order of 10^{-5}Φ _0/Hz^{1/2}; the resolution is expected to improve as the temperature is lowered.

Paleomagnetic Analysis Using SQUID Microscopy

NASA Technical Reports Server (NTRS)

Weiss, Benjamin P.; Lima, Eduardo A.; Fong, Luis E.; Baudenbacher, Franz J.

2007-01-01

Superconducting quantum interference device (SQUID) microscopes are a new generation of instruments that map magnetic fields with unprecedented spatial resolution and moment sensitivity. Unlike standard rock magnetometers, SQUID microscopes map magnetic fields rather than measuring magnetic moments such that the sample magnetization pattern must be retrieved from source model fits to the measured field data. In this paper, we presented the first direct comparison between paleomagnetic analyses on natural samples using joint measurements from SQUID microscopy and moment magnetometry. We demonstrated that in combination with apriori geologic and petrographic data, SQUID microscopy can accurately characterize the magnetization of lunar glass spherules and Hawaiian basalt. The bulk moment magnitude and direction of these samples inferred from inversions of SQUID microscopy data match direct measurements on the same samples using moment magnetometry. In addition, these inversions provide unique constraints on the magnetization distribution within the sample. These measurements are among the most sensitive and highest resolution quantitative paleomagnetic studies of natural remanent magnetization to date. We expect that this technique will be able to extend many other standard paleomagnetic techniques to previously inaccessible microscale samples.

Aperture effects in squid jet propulsion.

PubMed

Staaf, Danna J; Gilly, William F; Denny, Mark W

2014-05-01

Squid are the largest jet propellers in nature as adults, but as paralarvae they are some of the smallest, faced with the inherent inefficiency of jet propulsion at a low Reynolds number. In this study we describe the behavior and kinematics of locomotion in 1 mm paralarvae of Dosidicus gigas, the smallest squid yet studied. They swim with hop-and-sink behavior and can engage in fast jets by reducing the size of the mantle aperture during the contraction phase of a jetting cycle. We go on to explore the general effects of a variable mantle and funnel aperture in a theoretical model of jet propulsion scaled from the smallest (1 mm mantle length) to the largest (3 m) squid. Aperture reduction during mantle contraction increases propulsive efficiency at all squid sizes, although 1 mm squid still suffer from low efficiency (20%) because of a limited speed of contraction. Efficiency increases to a peak of 40% for 1 cm squid, then slowly declines. Squid larger than 6 cm must either reduce contraction speed or increase aperture size to maintain stress within maximal muscle tolerance. Ecological pressure to maintain maximum velocity may lead them to increase aperture size, which reduces efficiency. This effect might be ameliorated by nonaxial flow during the refill phase of the cycle. Our model's predictions highlight areas for future empirical work, and emphasize the existence of complex behavioral options for maximizing efficiency at both very small and large sizes.

Commercialization of Medium Voltage HTS Triax TM Cable Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Knoll, David

2012-12-31

The original project scope that was established in 2007 aimed to install a 1,700 meter (1.1 mile) medium voltage HTS Triax{TM} cable system into the utility grid in New Orleans, LA. In 2010, however, the utility partner withdrew from the project, so the 1,700 meter cable installation was cancelled and the scope of work was reduced. The work then concentrated on the specific barriers to commercialization of HTS cable technology. The modified scope included long-length HTS cable design and testing, high voltage factory test development, optimized cooling system development, and HTS cable life-cycle analysis. In 2012, Southwire again analyzed themore » market for HTS cables and deemed the near term market acceptance to be low. The scope of work was further reduced to the completion of tasks already started and to testing of the existing HTS cable system in Columbus, OH. The work completed under the project included: • Long-length cable modeling and analysis • HTS wire evaluation and testing • Cable testing for AC losses • Optimized cooling system design • Life cycle testing of the HTS cable in Columbus, OH • Project management. The 200 meter long HTS Triax{TM} cable in Columbus, OH was incorporated into the project under the initial scope changes as a test bed for life cycle testing as well as the site for an optimized HTS cable cooling system. The Columbus cable utilizes the HTS TriaxTM design, so it provided an economical tool for these of the project tasks.« less

OpenSQUID: A Flexible Open-Source Software Framework for the Control of SQUID Electronics

DOE PAGES

Jaeckel, Felix T.; Lafler, Randy J.; Boyd, S. T. P.

2013-02-06

We report commercially available computer-controlled SQUID electronics are usually delivered with software providing a basic user interface for adjustment of SQUID tuning parameters, such as bias current, flux offset, and feedback loop settings. However, in a research context it would often be useful to be able to modify this code and/or to have full control over all these parameters from researcher-written software. In the case of the STAR Cryoelectronics PCI/PFL family of SQUID control electronics, the supplied software contains modules for automatic tuning and noise characterization, but does not provide an interface for user code. On the other hand, themore » Magnicon SQUIDViewer software package includes a public application programming interface (API), but lacks auto-tuning and noise characterization features. To overcome these and other limitations, we are developing an "open-source" framework for controlling SQUID electronics which should provide maximal interoperability with user software, a unified user interface for electronics from different manufacturers, and a flexible platform for the rapid development of customized SQUID auto-tuning and other advanced features. Finally, we have completed a first implementation for the STAR Cryoelectronics hardware and have made the source code for this ongoing project available to the research community on SourceForge (http://opensquid.sourceforge.net) under the GNU public license.« less

Squid - a simple bioinformatics grid.

PubMed

Carvalho, Paulo C; Glória, Rafael V; de Miranda, Antonio B; Degrave, Wim M

2005-08-03

BLAST is a widely used genetic research tool for analysis of similarity between nucleotide and protein sequences. This paper presents a software application entitled "Squid" that makes use of grid technology. The current version, as an example, is configured for BLAST applications, but adaptation for other computing intensive repetitive tasks can be easily accomplished in the open source version. This enables the allocation of remote resources to perform distributed computing, making large BLAST queries viable without the need of high-end computers. Most distributed computing / grid solutions have complex installation procedures requiring a computer specialist, or have limitations regarding operating systems. Squid is a multi-platform, open-source program designed to "keep things simple" while offering high-end computing power for large scale applications. Squid also has an efficient fault tolerance and crash recovery system against data loss, being able to re-route jobs upon node failure and recover even if the master machine fails. Our results show that a Squid application, working with N nodes and proper network resources, can process BLAST queries almost N times faster than if working with only one computer. Squid offers high-end computing, even for the non-specialist, and is freely available at the project web site. Its open-source and binary Windows distributions contain detailed instructions and a "plug-n-play" instalation containing a pre-configured example.

Development of a single-phase 30 m HTS power cable

NASA Astrophysics Data System (ADS)

Cho, Jeonwook; Bae, Joon-Han; Kim, Hae-Jong; Sim, Ki-Deok; Kim, Seokho; Jang, Hyun-Man; Lee, Chang-Young; Kim, Dong-Wook

2006-05-01

HTS power transmission cables appear to be the replacement and retrofitting of underground cables in urban areas and HTS power transmission cable offers a number of technical and economic merits compared to the normal conductor cable system. A 30 m long, single-phase 22.9 kV class HTS power transmission cable system has been developed by Korea Electrotechnology Research Institute (KERI), LS Cable Ltd., and Korea Institute of Machinery and Materials (KIMM), which is one of the 21st century frontier project in Korea since 2001. The HTS power cable has been developed, cooled down and tested to obtain realistic thermal and electrical data on HTS power cable system. The evaluation results clarified such good performance of HTS cable that DC critical current of the HTS cable was 3.6 kA and AC loss was 0.98 W/m at 1260 Arms and shield current was 1000 Arms. These results proved the basic properties for 22.9 kV HTS power cable. As a next step, we have been developing a 30 m, three-phase 22.9 kV, 50 MV A HTS power cable system and long term evaluation is in progress now.

Biofunctional Properties of Enzymatic Squid Meat Hydrolysate

PubMed Central

Choi, Joon Hyuk; Kim, Kyung-Tae; Kim, Sang Moo

2015-01-01

Squid is one of the most important commercial fishes in the world and is mainly utilized or consumed as sliced raw fish or as processed products. The biofunctional activities of enzymatic squid meat hydrolysate were determined to develop value-added products. Enzymatic squid hydrolysate manufactured by Alcalase effectively quenched 1,1-diphenyl-2-picrylhydrazyl radical, hydroxyl radical, and hydrogen peroxide radical with IC50 values of 311, 3,410, and 111.5 μg/mL, respectively. Angiotensin I-converting enzyme inhibitory activity of squid hydrolysate was strong with an IC50 value of 145.1 μg/mL, while tyrosinase inhibitory activity with an IC50 value of 4.72 mg/mL was moderately low. Overall, squid meat hydrolysate can be used in food or cosmetic industries as a bioactive ingredient and possibly be used in the manufacture of seasoning, bread, noodle, or cosmetics. PMID:25866752

Novel Hadamard transform spectrometer realized using a dynamically driven micromirror array as a light modulator

NASA Astrophysics Data System (ADS)

Hanf, Marian; Schaporin, Alexey V.; Hahn, Ramon; Doetzel, Wolfram; Gessner, Thomas

2005-01-01

The paper deals with a novel setup of a Hadamard transform spectrometer (HTS) which encoding mask is realized by a micro mirror array. In contrast to other applications of an HTS the mirrors of the array are not statically switched but dynamically driven to oscillate at the same frequency. The Hadamard transform is obtained by shifting the phase shift of oscillation. The paper gives a brief introduction in the entity of the Hadamard transform technique. The driving and detection circuits are presented and first measurement results are discussed.

Development of toroid-type HTS DC reactor series for HVDC system

NASA Astrophysics Data System (ADS)

Kim, Kwangmin; Go, Byeong-Soo; Park, Hea-chul; Kim, Sung-kyu; Kim, Seokho; Lee, Sangjin; Oh, Yunsang; Park, Minwon; Yu, In-Keun

2015-11-01

This paper describes design specifications and performance of a toroid-type high-temperature superconducting (HTS) DC reactor. The first phase operation targets of the HTS DC reactor were 400 mH and 400 A. The authors have developed a real HTS DC reactor system during the last three years. The HTS DC reactor was designed using 2G GdBCO HTS wires. The HTS coils of the toroid-type DC reactor magnet were made in the form of a D-shape. The electromagnetic performance of the toroid-type HTS DC reactor magnet was analyzed using the finite element method program. A conduction cooling method was adopted for reactor magnet cooling. The total system has been successfully developed and tested in connection with LCC type HVDC system. Now, the authors are studying a 400 mH, kA class toroid-type HTS DC reactor for the next phase research. The 1500 A class DC reactor system was designed using layered 13 mm GdBCO 2G HTS wire. The expected operating temperature is under 30 K. These fundamental data obtained through both works will usefully be applied to design a real toroid-type HTS DC reactor for grid application.

Modelling ac ripple currents in HTS coated conductors

NASA Astrophysics Data System (ADS)

Xu, Zhihan; Grilli, Francesco

2015-10-01

Dc transmission using high temperature superconducting (HTS) coated conductors (CCs) offers a promising solution to the globally growing demand for effective, reliable and economic transmission of green energy up to the gigawatt level over very long distances. The credible estimation of the losses and thereby the heat dissipation involved, where ac ripples (introduced in rectification/ac-dc conversion) are viewed as a potential source of notable contribution, is highly essential for the rational design of practical HTS dc transmission cables and corresponding cryogenic systems to fulfil this demand. Here we report a targeted modelling study into the ac losses in a HTS CC subject to dc and ac ripple currents simultaneously, by solving Maxwell’s equations using the finite element method (FEM) in the commercial software package COMSOL. It is observed that the instantaneous loss exhibits only one peak per cycle in the HTS CC subject to sinusoidal ripples, given that the amplitude of the ac ripples is smaller than approximately 20% of that of the dc current. This is a distinct contrast to the usual observation of two peaks per cycle in a HTS CC subject to ac currents only. The unique mechanism is also revealed, which is directly associated with the finding that, around any local minima of the applied ac ripples, the critical state of -J c is never reached at the edges of the HTS CC, as it should be according to the Bean model. When running further into the longer term, it is discovered that the ac ripple loss of the HTS CC in full-wave rectification decays monotonically, at a speed which is found to be insensitive to the frequency of the applied ripples within our targeted situations, to a relatively low level of approximately 1.38 × 10-4 W m-1 in around 1.7 s. Comparison between this level and other typical loss contributions in a HTS dc cable implies that ac ripple currents in HTS CCs should only be considered as a minor source of dissipation in superconducting dc

US effort on HTS power transformers

NASA Astrophysics Data System (ADS)

Mehta, S.

2011-11-01

Waukesha Electric Systems has been working in HTS power transformers development program under the auspices of US Government Department of Energy since 1994. This presentation will describe various milestones for this program and program history along with the lessons learned along the way. Our motivations for working on this development program based on man benefits offered by HTS power transformers to power delivery systems will be discussed. Based on various issues encountered during execution of many HTS projects, DOE has set up an independent program review process that is lead by team of experts. This team reviews are integral part of all DOE HTS projects. Success of all projects would be greatly enhanced by identifying critical issues early in the program. Requiring appropriate actions to mitigate the issues before processing further will lead to proactive interrogation and incorporation of expert's ideas in the project plans. Working of this review process will be also described in this presentation. Waukesha Electric Systems team including: Superpower-Inc, Oak Ridge National Laboratory, University of Houston Center for Superconductivity and Southern California Edison company was awarded a cost share grant by US Government in 2010 for development of a fault current limiting HTS power transformer. This multi year's program will require design, manufacture, installation, and monitoring of a 28 MVA tree phase transformer installed at Irvine CA. Smart Grid demonstration site. Transformer specifications along with requirements for fault current limiting and site requirement will be discussed. Design and development of various sub systems in support of this program including: HTS conductor performance specification, Dielectric system design approach, Dewar development for containing phase assemblies, cryo-cooling system design approach, etc. will be described. Finally; overall program schedule, critical milestone events, test plans and progress to date will be

A new approach for AC loss reduction in HTS transformer using auxiliary windings, case study: 25 kA HTS current injection transformer

NASA Astrophysics Data System (ADS)

Heydari, Hossein; Faghihi, Faramarz; Aligholizadeh, Reza

2008-01-01

AC loss is one of the important parameters in HTS (high temperature superconducting) AC devices. Among the HTS AC power devices, the transformer is an essential part in the electrical power system. The AC losses in an HTS tape depend on the magnetic field. One of the techniques usually adopted to mitigate the unwanted magnetic field is using a system of coils that produce a magnetic field opposite to the incident one, reducing the total magnetic field. In this paper adding two auxiliary windings to the HTS transformer to produce this opposite magnetic field is proposed. The proper use of these auxiliary windings could reduce the leakage flux and, therefore, the AC loss. A mathematical model is used to describe the behaviour of a transformer operating with auxiliary windings, based on the theory of electromagnetic coupled circuits. The influence of the auxiliary windings on the leakage field is studied by the finite element method (FEM) and the AC loss of an HTS transformer was calculated. Also, the simulation results show that employing auxiliary windings will improve the HTS transformer efficiency.

Electromagnetic Performance Calculation of HTS Linear Induction Motor for Rail Systems

NASA Astrophysics Data System (ADS)

Liu, Bin; Fang, Jin; Cao, Junci; Chen, Jie; Shu, Hang; Sheng, Long

2017-07-01

According to a high temperature superconducting (HTS) linear induction motor (LIM) designed for rail systems, the influence of electromagnetic parameters and mechanical structure parameters on the electromagnetic horizontal thrust, vertical force of HTS LIM and the maximum vertical magnetic field of HTS windings are analyzed. Through the research on the vertical field of HTS windings, the development regularity of the HTS LIM maximum input current with different stator frequency and different thickness value of the secondary conductive plate is obtained. The theoretical results are of great significance to analyze the stability of HTS LIM. Finally, based on theory analysis, HTS LIM test platform was built and the experiment was carried out with load. The experimental results show that the theoretical analysis is correct and reasonable.

A method for simulating a flux-locked DC SQUID

NASA Technical Reports Server (NTRS)

Gutt, G. M.; Kasdin, N. J.; Condron, M. R., II; Muhlfelder, B.; Lockhart, J. M.; Cromar, M. W.

1993-01-01

The authors describe a computationally efficient and accurate method for simulating a dc SQUID's V-Phi (voltage-flux) and I-V characteristics which has proven valuable in evaluating and improving various SQUID readout methods. The simulation of the SQUID is based on fitting of previously acquired data from either a real or a modeled device using the Fourier transform of the V-Phi curve. This method does not predict SQUID behavior, but rather is a way of replicating a known behavior efficiently with portability into various simulation programs such as SPICE. The authors discuss the methods used to simulate the SQUID and the flux-locking control electronics, and present specific examples of this approach. Results include an estimate of the slew rate and linearity of a simple flux-locked loop using a characterized dc SQUID.

Superconducting Detector Arrays for Astrophysics

NASA Technical Reports Server (NTRS)

Chervenak, James

2008-01-01

The next generation of astrophysics instruments will feature an order of magnitude more photon sensors or sensors that have an order of magnitude greater sensitivity. Since detector noise scales with temperature, a number of candidate technologies have been developed that use the intrinsic advantages of detector systems that operate below 1 Kelvin. Many of these systems employ of the superconducting phenomena that occur in metals at these temperatures to build ultrasensitive detectors and low-noise, low-power readout architectures. I will present one such system in use today to meet the needs of the astrophysics community at millimeter and x-ray wavelengths. Our group at NASA in collaboration with Princeton, NIST, Boulder and a number of other groups is building large format arrays of superconducting transition edge sensors (TES) read out with multiplexed superconducting quantum interference devices (SQUID). I will present the high sensitivity we have achieved in multiplexed x-ray sensors with the TES technology and describe the construction of a 1000-sensor TES/SQUID array for microwave measurements. With our collaboration's deployment of a kilopixel TES array for 2 mm radiation at the Atacarna Cosmology Telescope in November 2007, we have first images of the lensed Cosmic Microwave Background at fine angular scales.

Code-division-multiplexed readout of large arrays of TES microcalorimeters

NASA Astrophysics Data System (ADS)

Morgan, K. M.; Alpert, B. K.; Bennett, D. A.; Denison, E. V.; Doriese, W. B.; Fowler, J. W.; Gard, J. D.; Hilton, G. C.; Irwin, K. D.; Joe, Y. I.; O'Neil, G. C.; Reintsema, C. D.; Schmidt, D. R.; Ullom, J. N.; Swetz, D. S.

2016-09-01

Code-division multiplexing (CDM) offers a path to reading out large arrays of transition edge sensor (TES) X-ray microcalorimeters with excellent energy and timing resolution. We demonstrate the readout of X-ray TESs with a 32-channel flux-summed code-division multiplexing circuit based on superconducting quantum interference device (SQUID) amplifiers. The best detector has energy resolution of 2.28 ± 0.12 eV FWHM at 5.9 keV and the array has mean energy resolution of 2.77 ± 0.02 eV over 30 working sensors. The readout channels are sampled sequentially at 160 ns/row, for an effective sampling rate of 5.12 μs/channel. The SQUID amplifiers have a measured flux noise of 0.17 μΦ0/√Hz (non-multiplexed, referred to the first stage SQUID). The multiplexed noise level and signal slew rate are sufficient to allow readout of more than 40 pixels per column, making CDM compatible with requirements outlined for future space missions. Additionally, because the modulated data from the 32 SQUID readout channels provide information on each X-ray event at the row rate, our CDM architecture allows determination of the arrival time of an X-ray event to within 275 ns FWHM with potential benefits in experiments that require detection of near-coincident events.

Cold SQUIDs and hot samples

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, T.S.C.

1997-05-01

Low transition temperature (low-{Tc}) and high-{Tc} Superconducting QUantum Interference Devices (SQUIDs) have been used to perform high-resolution magnetic measurements on samples whose temperatures are much higher than the operating temperatures of the devices. Part 1 of this work focuses on measurements of the rigidity of flux vortices in high-{Tc} superconductors using two low-{Tc} SQUIDs, one on either side of a thermally-insulated sample. The correlation between the signals of the SQUIDs is a direct measure of the extent of correlation between the movements of opposite ends of vortices. These measurements were conducted under the previously-unexplored experimental conditions of nominally-zero applied magneticmore » field, such that vortex-vortex interactions were unimportant, and with zero external current. At specific temperatures, the authors observed highly-correlated noise sources, suggesting that the vortices moved as rigid rods. At other temperatures, the noise was mostly uncorrelated, suggesting that the relevant vortices were pinned at more than one point along their length. Part 2 describes the design, construction, performance, and applications of a scanning high-{Tc} SQUID microscope optimized for imaging room-temperature objects with very high spatial resolution and magnetic source sensitivity.« less

An Analytical Technique to Elucidate Field Impurities From Manufacturing Uncertainties of an Double Pancake Type HTS Insert for High Field LTS/HTS NMR Magnets

PubMed Central

Hahn, Seung-yong; Ahn, Min Cheol; Bobrov, Emanuel Saul; Bascuñán, Juan; Iwasa, Yukikazu

2010-01-01

This paper addresses adverse effects of dimensional uncertainties of an HTS insert assembled with double-pancake coils on spatial field homogeneity. Each DP coil was wound with Bi2223 tapes having dimensional tolerances larger than one order of magnitude of those accepted for LTS wires used in conventional NMR magnets. The paper presents: 1) dimensional variations measured in two LTS/HTS NMR magnets, 350 MHz (LH350) and 700 MHz (LH700), both built and operated at the Francis Bitter Magnet Laboratory; and 2) an analytical technique and its application to elucidate the field impurities measured with the two LTS/HTS magnets. Field impurities computed with the analytical model and those measured with the two LTS/HTS magnets agree quite well, demonstrating that this analytical technique is applicable to design a DP-assembled HTS insert with an improved field homogeneity for a high-field LTS/HTS NMR magnet. PMID:20407595

Critical current studies of a HTS rectangular coil

NASA Astrophysics Data System (ADS)

Zhong, Z.; Chudy, M.; Ruiz, H. S.; Zhang, X.; Coombs, T.

2017-05-01

Nowadays, superconducting high field magnets are used in numerous applications due to their superior properties. High temperature superconductors (HTS) are usually used for production of circular pancake or racetrack coils. However different geometries of HTS coils might be required for some specific applications. In this study, the HTS coil wound on a rectangular frame was fully characterized in homogeneous DC background field. The study contains measurements of critical current angular dependencies. The critical current of the entire coil and two selected strands under different magnitudes and orientations of external magnetic fields are measured. The critical regions of the coil in different angular regimes are determined. This study brings better understanding of the in- field performance of HTS coils wound on frames with right-angles.

Parametric Study of HTS Coil Quench Protection Strategies

NASA Astrophysics Data System (ADS)

Seibert, Joseph; Zarnstorff, Michael; Zhai, Yuhu

2016-10-01

Next generation fusion devices require high magnetic fields to adequately contain burning plasmas. Use of high temperature superconducting (HTS) coils to generate these magnetic fields would lower energy cost of operation as well as increase stability of the superconducting state compared to low temperature superconducting coils. However, use of HTS coils requires developing quench protection strategies to prevent damage to the coils. One technique involves the utilization of copper discs and other conductors mutually coupled to the HTS coil to quickly extract the current from the coil. Another technique allows conduction between HTS turns to reduce the current in the coil during quench. This project describes a parametric study of the HTS coil and resistive-conductor setup in order to determine limiting cases of the geometry in an attempt to optimize current extraction and coil protection during quench scenarios. This work was supported in part by the U.S. Department of Energy, Office of Science, Office of Workforce Development for Teachers and Scientists (WDTS) under the Science Undergraduate Laboratory Internship (SULI) program.

Study on AC loss measurements of HTS power cable for standardizing

NASA Astrophysics Data System (ADS)

Mukoyama, Shinichi; Amemiya, Naoyuki; Watanabe, Kazuo; Iijima, Yasuhiro; Mido, Nobuhiro; Masuda, Takao; Morimura, Toshiya; Oya, Masayoshi; Nakano, Tetsutaro; Yamamoto, Kiyoshi

2017-09-01

High-temperature superconducting power cables (HTS cables) have been developed for more than 20 years. In addition of the cable developments, the test methods of the HTS cables have been discussed and proposed in many laboratories and companies. Recently the test methods of the HTS cables is required to standardize and to common in the world. CIGRE made the working group (B1-31) for the discussion of the test methods of the HTS cables as a power cable, and published the recommendation of the test method. Additionally, IEC TC20 submitted the New Work Item Proposal (NP) based on the recommendation of CIGRE this year, IEC TC20 and IEC TC90 started the standardization work on Testing of HTS AC cables. However, the individual test method that used to measure a performance of HTS cables hasn’t been established as world’s common methods. The AC loss is one of the most important properties to disseminate low loss and economical efficient HTS cables in the world. We regard to establish the method of the AC loss measurements in rational and in high accuracy. Japan is at a leading position in the AC loss study, because Japanese researchers have studied on the AC loss technically and scientifically, and also developed the effective technologies for the AC loss reduction. The JP domestic commission of TC90 made a working team to discussion the methods of the AC loss measurements for aiming an international standard finally. This paper reports about the AC loss measurement of two type of the HTS conductors, such as a HTS conductor without a HTS shield and a HTS conductor with a HTS shield. The AC loss measurement method is suggested by the electrical method..

High-resolution photon spectroscopy with a microwave-multiplexed 4-pixel transition edge sensor array

NASA Astrophysics Data System (ADS)

Guss, Paul; Rabin, Michael; Croce, Mark; Hoteling, Nathan; Schwellenbach, David; Kruschwitz, Craig; Mocko, Veronika; Mukhopadhyay, Sanjoy

2017-09-01

We demonstrate very high-resolution photon spectroscopy with a microwave-multiplexed 4-pixel transition edge sensor (TES) array. The readout circuit consists of superconducting microwave resonators coupled to radio frequency superconducting-quantum-interference devices (RF-SQUIDs) and transduces changes in input current to changes in phase of a microwave signal. We used a flux-ramp modulation to linearize the response and avoid low-frequency noise. The result is a very high-resolution photon spectroscopy with a microwave-multiplexed 4-pixel transition edge sensor array. We performed and validated a small-scale demonstration and test of all the components of our concept system, which encompassed microcalorimetry, microwave multiplexing, RF-SQUIDs, and software-defined radio (SDR). We shall display data we acquired in the first simultaneous combination of all key innovations in a 4-pixel demonstration, including microcalorimetry, microwave multiplexing, RF-SQUIDs, and SDR. We present the energy spectrum of a gadolinium-153 (153Gd) source we measured using our 4-pixel TES array and the RF-SQUID multiplexer. For each pixel, one can observe the two 97.4 and 103.2 keV photopeaks. We measured the 153Gd photon source with an achieved energy resolution of 70 eV, full width half maximum (FWHM) at 100 keV, and an equivalent readout system noise of 90 pA/pHz at the TES. This demonstration establishes a path for the readout of cryogenic x-ray and gamma ray sensor arrays with more elements and spectral resolving powers. We believe this project has improved capabilities and substantively advanced the science useful for missions such as nuclear forensics, emergency response, and treaty verification through the explored TES developments.

Low Field Squid MRI Devices, Components and Methods

NASA Technical Reports Server (NTRS)

Hahn, Inseob (Inventor); Penanen, Konstantin I. (Inventor); Eom, Byeong H. (Inventor)

2013-01-01

Low field SQUID MRI devices, components and methods are disclosed. They include a portable low field (SQUID)-based MRI instrument and a portable low field SQUID-based MRI system to be operated under a bed where a subject is adapted to be located. Also disclosed is a method of distributing wires on an image encoding coil system adapted to be used with an NMR or MRI device for analyzing a sample or subject and a second order superconducting gradiometer adapted to be used with a low field SQUID-based MRI device as a sensing component for an MRI signal related to a subject or sample.

Low Field Squid MRI Devices, Components and Methods

NASA Technical Reports Server (NTRS)

Penanen, Konstantin I. (Inventor); Eom, Byeong H. (Inventor); Hahn, Inseob (Inventor)

2014-01-01

Low field SQUID MRI devices, components and methods are disclosed. They include a portable low field (SQUID)-based MRI instrument and a portable low field SQUID-based MRI system to be operated under a bed where a subject is adapted to be located. Also disclosed is a method of distributing wires on an image encoding coil system adapted to be used with an NMR or MRI device for analyzing a sample or subject and a second order superconducting gradiometer adapted to be used with a low field SQUID-based MRI device as a sensing component for an MRI signal related to a subject or sample.

Low field SQUID MRI devices, components and methods

NASA Technical Reports Server (NTRS)

Penanen, Konstantin I. (Inventor); Eom, Byeong H. (Inventor); Hahn, Inseob (Inventor)

2011-01-01

Low field SQUID MRI devices, components and methods are disclosed. They include a portable low field (SQUID)-based MRI instrument and a portable low field SQUID-based MRI system to be operated under a bed where a subject is adapted to be located. Also disclosed is a method of distributing wires on an image encoding coil system adapted to be used with an NMR or MRI device for analyzing a sample or subject and a second order superconducting gradiometer adapted to be used with a low field SQUID-based MRI device as a sensing component for an MRI signal related to a subject or sample.

Low field SQUID MRI devices, components and methods

NASA Technical Reports Server (NTRS)

Penanen, Konstantin I. (Inventor); Eom, Byeong H (Inventor); Hahn, Inseob (Inventor)

2010-01-01

Low field SQUID MRI devices, components and methods are disclosed. They include a portable low field (SQUID)-based MRI instrument and a portable low field SQUID-based MRI system to be operated under a bed where a subject is adapted to be located. Also disclosed is a method of distributing wires on an image encoding coil system adapted to be used with an NMR or MRI device for analyzing a sample or subject and a second order superconducting gradiometer adapted to be used with a low field SQUID-based MRI device as a sensing component for an MRI signal related to a subject or sample.

Allometry indicates giant eyes of giant squid are not exceptional.

PubMed

Schmitz, Lars; Motani, Ryosuke; Oufiero, Christopher E; Martin, Christopher H; McGee, Matthew D; Gamarra, Ashlee R; Lee, Johanna J; Wainwright, Peter C

2013-02-18

The eyes of giant and colossal squid are among the largest eyes in the history of life. It was recently proposed that sperm whale predation is the main driver of eye size evolution in giant squid, on the basis of an optical model that suggested optimal performance in detecting large luminous visual targets such as whales in the deep sea. However, it is poorly understood how the eye size of giant and colossal squid compares to that of other aquatic organisms when scaling effects are considered. We performed a large-scale comparative study that included 87 squid species and 237 species of acanthomorph fish. While squid have larger eyes than most acanthomorphs, a comparison of relative eye size among squid suggests that giant and colossal squid do not have unusually large eyes. After revising constants used in a previous model we found that large eyes perform equally well in detecting point targets and large luminous targets in the deep sea. The eyes of giant and colossal squid do not appear exceptionally large when allometric effects are considered. It is probable that the giant eyes of giant squid result from a phylogenetically conserved developmental pattern manifested in very large animals. Whatever the cause of large eyes, they appear to have several advantages for vision in the reduced light of the deep mesopelagic zone.

The UT 19-channel DC SQUID based neuromagnetometer.

PubMed

ter Brake, H J; Flokstra, J; Jaszczuk, W; Stammis, R; van Ancum, G K; Martinez, A; Rogalla, H

1991-01-01

A 19-channel DC SQUID based neuromagnetometer is under construction at the University of Twente (UT). Except for the cryostat all elements of the system are developed at the UT. It comprises 19 wire-wound first-order gradiometers in a hexagonal configuration. The gradiometers are connected to planar DC SQUIDs fabricated with a Nb/Al, AlO kappa/Nb technology. For this connection we developed a method to bond a Nb wire to a Nb thin-film. The SQUIDs are placed in compartmentalised Nb modules. Further, external feedback is incorporated in order to eliminate cross talk between the gradiometers. The electronics basically consist of a phase-locked loop operating with a modulation frequency of 100 kHz. Between SQUID and preamplifier a small transformer is used to limit the noise contribution of the preamplifier. In the paper the overall system is described, and special attention is paid to the SQUID module (bonding, compartments, external-feedback setup, output transformer).

Efficient growth of HTS films with volatile elements

DOEpatents

Siegal, M.P.; Overmyer, D.L.; Dominguez, F.

1998-12-22

A system is disclosed for applying a volatile element-HTS layer, such as Tl-HTS, to a substrate in a multiple zone furnace, said method includes heating at higher temperature, in one zone of the furnace, a substrate and adjacent first source of Tl-HTS material, to sublimate Tl-oxide from the source to the substrate; and heating at lower temperature, in a separate zone of the furnace, a second source of Tl-oxide to replenish the first source of Tl-oxide from the second source. 3 figs.

Superconducting Electric Machine with Permanent Magnets and Bulk HTS Elements

NASA Astrophysics Data System (ADS)

Levin, A. V.; Vasich, P. S.; Dezhin, D. S.; Kovalev, L. K.; Kovalev, K. L.; Poltavets, V. N.; Penkin, V. T.

Theoretical methods of calculating of two-dimensional magnetic fields, inductive parameters and output characteristics of the new type of high-temperature superconducting (HTS) synchronous motors with a composite rotor are presented. The composite rotor has the structure containing HTS flat elements, permanent magnets and ferromagnetic materials. The developed calculation model takes into account the concentrations and physical properties of these rotor elements. The simulation results of experimental HTS motor with a composite rotor are presented. The application of new type of HTS motor in different constructions of industrial high dynamic drivers is discussed.

Spatial and Temporal Variations of a Screening Current Induced Magnetic Field in a Double-Pancake HTS Insert of an LTS/HTS NMR Magnet

PubMed Central

Ahn, Min Cheol; Yagai, Tsuyoshi; Hahn, Seungyong; Ando, Ryuya; Bascuñán, Juan; Iwasa, Yukikazu

2010-01-01

This paper presents experimental and simulation results of a screening current induced magnetic field (SCF) in a high temperature superconductor (HTS) insert that constitutes a low-/high-temperature superconductor (LTS/HTS) NMR magnet. In this experiment, the HTS insert, a stack of 50 double-pancake coils, each wound with Bi2223 tape, was operated at 77 K. A screening current was induced in the HTS insert by three magnetic field sources: 1) a self field from the HTS insert; 2) an external field from a 5-T background magnet; and 3) combinations of 1) and 2). For each field excitation, which induced an SCF, its axial field distribution and temporal variations were measured and compared with simulation results based on the critical state model. Agreement on field profile between experiment and simulation is satisfactory but more work is needed to make the simulation useful for designing shim coils that will cancel the SCF. PMID:20401187

Statistical characterization of voltage-biased SQUIDs with weakly damped junctions

NASA Astrophysics Data System (ADS)

Liu, Chao; Zhang, Yi; Mück, Michael; Zhang, Shulin; Krause, Hans-Joachim; Braginski, Alex I.; Zhang, Guofeng; Wang, Yongliang; Kong, Xiangyan; Xie, Xiaoming; Offenhäusser, Andreas; Jiang, Mianheng

2013-06-01

Recently, it has been shown that voltage-biased readout of SQUIDs with weakly damped junctions (large Stewart-McCumber parameter βc, due to high shunt resistance) is useful for suppression of preamplifier noise. We experimentally studied the characteristics of 53 planar niobium-SQUID magnetometers with junction shunt resistors RJ nominally of 30 Ω fabricated on 5 × 5 mm2 chips. The field-to-flux transfer coefficient ∂B/∂Φ of the magnetometers was 1.5 nT/Φ0, with a SQUID loop inductance Ls of about 350 pH. The distributions of important SQUID parameters, such as the current swing Iswing, the dynamic resistance Rd, and the flux-to-voltage transfer coefficient ∂V/∂Φ, are given. Nearly all the SQUIDs could be stably operated in the voltage bias mode and their ∂V/∂Φ reached a large mean value of 380 μV/Φ0. In this case, the SQUIDs can be read out directly by a commercial operational amplifier without any additional means to suppress preamplifier noise. The mean flux noise of the SQUIDs was found to be 4.5 μΦ0 Hz-1/2, corresponding to a field resolution of 7 fT Hz-1/2. To demonstrate the applicability of these SQUIDs in the direct readout scheme, a simple four-channel SQUID gradiometer system was set up to perform magnetocardiography and magnetoencephalography measurements in a magnetically shielded room.

Temperature-dependent performance of all-NbN DC-SQUID magnetometers

NASA Astrophysics Data System (ADS)

Liu, Quansheng; Wang, Huiwu; Zhang, Qiyu; Wang, Hai; Peng, Wei; Wang, Zhen

2017-05-01

Integrated NbN direct current superconducting quantum interference device (DC-SQUID) magnetometers were developed based on high-quality epitaxial NbN/AlN/NbN Josephson junctions for SQUID applications operating at high temperatures. We report the current-voltage and voltage-flux characteristics and the noise performance of the NbN DC-SQUIDs for temperatures ranging from 4.2 to 9 K. The critical current and voltage swing of the DC-SQUIDs decreased by 15% and 25%, respectively, as the temperature was increased from 4.2 to 9 K. The white flux noise of the DC-SQUID magnetometer at 1 kHz increased from 3.9 μΦ0/Hz1/2 at 4.2 K to 4.8 μΦ0/Hz1/2 at 9 K with 23% increase, corresponding to the magnetic field noise of 6.6 and 8.1 fT/Hz1/2, respectively. The results show that NbN DC-SQUIDs improve the tolerance of the operating temperatures and temperature fluctuations in SQUID applications.

Scanning SQUID sampler with 40-ps time resolution

NASA Astrophysics Data System (ADS)

Cui, Zheng; Kirtley, John R.; Wang, Yihua; Kratz, Philip A.; Rosenberg, Aaron J.; Watson, Christopher A.; Gibson, Gerald W.; Ketchen, Mark B.; Moler, Kathryn. A.

2017-08-01

Scanning Superconducting QUantum Interference Device (SQUID) microscopy provides valuable information about magnetic properties of materials and devices. The magnetic flux response of the SQUID is often linearized with a flux-locked feedback loop, which limits the response time to microseconds or longer. In this work, we present the design, fabrication, and characterization of a novel scanning SQUID sampler with a 40-ps time resolution and linearized response to periodically triggered signals. Other design features include a micron-scale pickup loop for the detection of local magnetic flux, a field coil to apply a local magnetic field to the sample, and a modulation coil to operate the SQUID sampler in a flux-locked loop to linearize the flux response. The entire sampler device is fabricated on a 2 mm × 2 mm chip and can be scanned over macroscopic planar samples. The flux noise at 4.2 K with 100 kHz repetition rate and 1 s of averaging is of order 1 mΦ0. This SQUID sampler will be useful for imaging dynamics in magnetic and superconducting materials and devices.

Scanning SQUID sampler with 40-ps time resolution.

PubMed

Cui, Zheng; Kirtley, John R; Wang, Yihua; Kratz, Philip A; Rosenberg, Aaron J; Watson, Christopher A; Gibson, Gerald W; Ketchen, Mark B; Moler, Kathryn A

2017-08-01

Scanning Superconducting QUantum Interference Device (SQUID) microscopy provides valuable information about magnetic properties of materials and devices. The magnetic flux response of the SQUID is often linearized with a flux-locked feedback loop, which limits the response time to microseconds or longer. In this work, we present the design, fabrication, and characterization of a novel scanning SQUID sampler with a 40-ps time resolution and linearized response to periodically triggered signals. Other design features include a micron-scale pickup loop for the detection of local magnetic flux, a field coil to apply a local magnetic field to the sample, and a modulation coil to operate the SQUID sampler in a flux-locked loop to linearize the flux response. The entire sampler device is fabricated on a 2 mm × 2 mm chip and can be scanned over macroscopic planar samples. The flux noise at 4.2 K with 100 kHz repetition rate and 1 s of averaging is of order 1 mΦ 0 . This SQUID sampler will be useful for imaging dynamics in magnetic and superconducting materials and devices.

Tracking Electromagnetic Energy With SQUIDs

NASA Technical Reports Server (NTRS)

2005-01-01

A superconducting quantum interference device (SQUID) is a gadget used to measure extremely weak signals, specifically magnetic flux. It can detect subtle changes in energy, up to 100 billion times weaker than the electromagnetic energy required to move a compass needle. SQUIDs are used for a variety of testing procedures where extreme sensitivity is required and where the test instrument need not come into direct contact with the test subject. NASA uses SQUIDs for remote, noncontact sensing in a variety of venues, including monitoring the Earth s magnetic field and tracking brain activity of pilots. Scientists at NASA s Goddard Space Flight Center have been making extensive use of this technology, from astrophysical research, to tracking the navigational paths of bees in flight to determine if they are using internal compasses. These very sensitive measurement devices have a wide variety of uses within NASA and even more uses within the commercial realm.

Performance of Large Format Transition Edge Sensor Microcalorimeter Arrays

NASA Technical Reports Server (NTRS)

Chervenak, J. A.; Adams, J. A.; Bandler, S. B.; Busch, S. E.; Eckart, M. E.; Ewin, A. E.; Finkbeiner, F. M.; Kilbourne, C. A.; Kelley, R. L.; Porst, J. P.;

Vector sensor for scanning SQUID microscopy

NASA Astrophysics Data System (ADS)

Dang, Vu The; Toji, Masaki; Thanh Huy, Ho; Miyajima, Shigeyuki; Shishido, Hiroaki; Hidaka, Mutsuo; Hayashi, Masahiko; Ishida, Takekazu

2017-07-01

We plan to build a novel 3-dimensional (3D) scanning SQUID microscope with high sensitivity and high spatial resolution. In the system, a vector sensor consists of three SQUID sensors and three pick-up coils realized on a single chip. Three pick-up coils are configured in orthogonal with each other to measure the magnetic field vector of X, Y, Z components. We fabricated some SQUID chips with one uniaxial pick-up coil or three vector pick-up coils and carried out fundamental measurements to reveal the basic characteristics. Josephson junctions (JJs) of sensors are designed to have the critical current density J c of 320 A/cm2, and the critical current I c becomes 12.5 μA for the 2.2μm × 2.2μm JJ. We carefully positioned the three pickup coils so as to keep them at the same height at the centers of all three X, Y and Z coils. This can be done by arranging them along single line parallel to a sample surface. With the aid of multilayer technology of Nb-based fabrication, we attempted to reduce an inner diameter of the pickup coils to enhance both sensitivity and spatial resolution. The method for improving a spatial resolution of a local magnetic field image is to employ an XYZ piezo-driven scanner for controlling the positions of the pick-up coils. The fundamental characteristics of our SQUID sensors confirmed the proper operation of our SQUID sensors and found a good agreement with our design parameters.

SQUID use for Geophysics: finding billions of dollars

NASA Astrophysics Data System (ADS)

Foley, Catherine

2014-03-01

Soon after their discovery, Jim Zimmerman saw the potential of using Superconducting Quantum Interference Devices, SQUIDs, for the study of Geophysics and undertook experiments to understand the magnetic phenomena of the Earth. However his early experiments were not successful. Nevertheless up to the early 1980's, some research effort in the use of SQUIDs for geophysics continued and many ideas of how you could use SQUIDs evolved. Their use was not adopted by the mining industry at that time for a range of reasons. The discovery of high temperature superconductors started a reinvigoration in the interest to use SQUIDs for mineral exploration. Several groups around the world worked with mining companies to develop both liquid helium and nitrogen cooled systems. The realisation of the achievable sensitivity that contributed to successful mineral discoveries and delineation led to real financial returns for miners. By the mid 2000's, SQUID systems for geophysics were finally being offered for sale by several start-up companies. This talk will tell the story of SQUID use in geophysics. It will start with the early work of the SQUID pioneers including that of Jim Zimmerman and John Clarke and will also cover the development since the early 1990's up to today of a number of magnetometers and gradiometers that have been successfully commercialised and used to create significant impact in the global resources industry. The talk will also cover some of the critical technical challenges that had to be overcome to succeed. It will focus mostly on magnetically unshielded systems used in the field although some laboratory-based systems will be discussed.

High-T(c) squid application in medicine and geophysics

NASA Technical Reports Server (NTRS)

Polushkin, V. N.; Uchaikin, S. V.; Vasiliev, B. V.

1991-01-01

In our laboratory of high-T(sub c), a one-hole squid was built from Y1Ba2Cu3O(7-x) ceramics obtained by a standard procedure of solid state reaction. The ceramics with critical current density J(sub c) is greater than 100 A/sq cm was selected. In the middle of a 10 x 10 x 2 mm ceramics pellet, a 0.8 mm hole was drilled in which the superconducting loop of the squid was located. Between the hole and the edge of the pellet, a cut was mechanically filed out with a bridge inside it connecting the superconducting ring. A scheme of the magnetometer is presented. The resonant frequency shift of the tank circuit, the connection of the squid with this circuit, and the squid inductance are evaluated. One of the most interesting fields of the squid-based magnetometer application is biomagnetism, particularly, the human heart magnetocardiogram measuring. The low-temperature squids were used in this area and many interesting and important scientific results have been obtained. The observations have shown that the main noise contribution was not due to the squid but to the Earth's magnetic field variations, industrial inductions, and mainly to the vibrations caused by liquid nitrogen boiling and by vibrations of the box. Further attempts are needed to reduce the magnetic noise inductions. Nevertheless, the estimations promise the maximum signal/noise relation of the high-T(sub c) squid-magnetocardiometer to be not less than 10:1 in a bandwidth of 60 Hz. Apparently, such resolution would be enough not only for steady cardiogram reading but even for thin structure investigation at average technique application.

Low noise niobium dc SQUID with a planar input coil

NASA Astrophysics Data System (ADS)

de Waal, V. J.; van den Hamer, P.; Klapwijk, T. M.

1983-02-01

A practical all-niobium dc superconducting quantum interference device (SQUID) with a niobium spiral input coil has been developed. The SQUID utilizes submicron Josephson junctions. The best intrinsic energy resolution obtained with a 1-nH SQUID is 4×10-32 J/Hz. A 20-turn 1.2-μH input coil is coupled to a 2.3-nH SQUID with an efficiency of 0.5. The energy resolution with respect to the coil is 1×10-30 J/Hz.

Large-scale HTS bulks for magnetic application

NASA Astrophysics Data System (ADS)

Werfel, Frank N.; Floegel-Delor, Uta; Riedel, Thomas; Goebel, Bernd; Rothfeld, Rolf; Schirrmeister, Peter; Wippich, Dieter

2013-01-01

ATZ Company has constructed about 130 HTS magnet systems using high-Tc bulk magnets. A key feature in scaling-up is the fabrication of YBCO melts textured multi-seeded large bulks with three to eight seeds. Except of levitation, magnetization, trapped field and hysteresis, we review system engineering parameters of HTS magnetic linear and rotational bearings like compactness, cryogenics, power density, efficiency and robust construction. We examine mobile compact YBCO bulk magnet platforms cooled with LN2 and Stirling cryo-cooler for demonstrator use. Compact cryostats for Maglev train operation contain 24 pieces of 3-seed bulks and can levitate 2500-3000 N at 10 mm above a permanent magnet (PM) track. The effective magnetic distance of the thermally insulated bulks is 2 mm only; the stored 2.5 l LN2 allows more than 24 h operation without refilling. 34 HTS Maglev vacuum cryostats are manufactured tested and operate in Germany, China and Brazil. The magnetic levitation load to weight ratio is more than 15, and by group assembling the HTS cryostats under vehicles up to 5 t total loads levitated above a magnetic track is achieved.

HTS thin films: Passive microwave components and systems integration issues

NASA Technical Reports Server (NTRS)

Miranda, F. A.; Chorey, C. M.; Bhasin, K. B.

1995-01-01

The excellent microwave properties of the High-Temperature-Superconductors (HTS) have been amply demonstrated in the laboratory by techniques such as resonant cavity, power transmission and microstrip resonator measurements. The low loss and high Q passive structures made possible with HTS, present attractive options for applications in commercial, military and spacebased systems. However, to readily insert HTS into these systems improvement is needed in such areas as repeatability in the deposition and processing of the HTS films, metal-contact formation, wire bonding, and overall film endurance to fabrication and assembly procedures. In this paper we present data compiled in our lab which illustrate many of the problems associated with these issues. Much of this data were obtained in the production of a space qualified hybrid receiver-downconverter module for the Naval Research Laboratory's High Temperature Superconductivity Space Experiment 2 (HTSSE-2). Examples of variations observed in starting films and finished circuits will be presented. It is shown that under identical processing the properties of the HTS films can degrade to varying extents. Finally, we present data on ohmic contacts and factors affecting their adhesion to HTS films, strength of wire bonds made to such contacts, and aging effects.

Whole-head SQUID system in a superconducting magnetic shield.

PubMed

Ohta, H; Matsui, T; Uchikawa, Y

2004-11-30

We have constructed a mobile whole-head SQUID system in a superconducting magnetic shield - a cylinder of high Tc superconductor BSCCO of 65 cm in diameter and 160 cm in length. We compared the noise spectra of several SQUID sensors of SNS Josephson junctions in the superconducting magnetic shield with those of the same SQUID sensors in a magnetically shielded room of Permalloy. The SQUID sensors in the superconducting magnetic shield are more than 100 times more sensitive than those in a magnetically shielded room of Permalloy below 1 Hz. We tested the whole-head SQUID system in the superconducting magnetic shield observing somatosensory signals evoked by stimulating the median nerve in the right wrist of patients by current pulses. We present data of 64 and 128 traces versus the common time axis for comparison. Most sensory responses of human brains phase out near 250 ms. However monotonic rhythms still remain even at longer latencies than 250 ms. The nodes of these rhythm are very narrow even at these longer latencies just indicating low noise characteristics of the SQUID system at low-frequencies. The current dipoles at the secondary somatosensory area SII are evoked at longer latencies than 250 ms contributing to a higher-level brain function. The SQUID system in a superconducting magnetic shield will also have advantages when it is used as a DC MEG to study very slow activities and function of the brain.

Timing of squid migration reflects North Atlantic climate variability.

PubMed

Sims, D W; Genner, M J; Southward, A J; Hawkins, S J

2001-12-22

The environmental and biotic conditions affecting fisheries for cephalopods are only partially understood. A problem central to this is how climate change may influence population movements by altering the availability of thermal resources. In this study we investigate the links between climate and sea-temperature changes and squid arrival time off southwestern England over a 20-year period. We show that veined squid (Loligo forbesi) migrate eastward in the English Channel earlier when water in the preceding months is warmer, and that higher temperatures and early arrival correspond with warm (positive) phases of the North Atlantic oscillation (NAO). The timing of squid peak abundance advanced by 120-150 days in the warmest years ('early' years) compared with the coldest ('late' years). Furthermore, sea-bottom temperature was closely linked to the extent of squid movement. Temperature increases over the five months prior to and during the month of peak squid abundance did not differ between early and late years, indicating squid responded to temperature changes independently of time of year. We conclude that the temporal variation in peak abundance of squid seen off Plymouth represents temperature-dependent movement, which is in turn mediated by climatic changes associated with the NAO. Such climate-mediated movement may be a widespread characteristic of cephalopod populations worldwide, and may have implications for future fisheries management because global warming may alter both the timing and location of peak population abundance.

Structural modeling of HTS tapes and cables

NASA Astrophysics Data System (ADS)

Allen, N. C.; Chiesa, L.; Takayasu, M.

2016-12-01

Structural finite element analysis (FEA) has been used as an insightful tool to investigate the electromechanical behavior of HTS REBCO tapes and twisted stacked-tape cables under tension, torsion, bending and combined loads. A novel technique was developed for modeling the layered composite structure of the 2G tapes with structural solid-shell elements in ANSYS®. The FEA models produced detailed strain information for the REBCO superconducting layer which was then paired with an analytical model to predict the critical current performance of the 2G HTS tapes under various loads. Two commercially available HTS tapes (SuperPower and SuNAM) under tension, torsion and combined tension-torsion were first analyzed with FEA and compared with available experimental results at 77 K. A sharp critical current degradation was experienced at the yield strength of the tapes under tension and below a 100 mm twist-pitch under torsion. Combined tension-torsion loads had a more gradual degradation of critical current for twist-pitches of 115 mm or shorter but had a negligible difference compared to pure tension for longer twist-pitches. Using the structural solid-shell technique for modeling 2G tapes in ANSYS®, an FEA methodology for simulating full scale three-dimensional HTS stacked-tape cables under pure bending was created. A model of a Twisted-Stacked Tape Cable (TSTC), a configuration first proposed at MIT, was initially developed and then adapted to the slotted-core HTS Cable-In-Conduit Conductor produced by the ENEA laboratory in Italy. The numerical axial strain of the HTS REBCO tapes within the cables as calculated by FEA were found to agree with an analytical model for two cases: perfect-slip (frictionless) and no-slip (bonded). The ENEA CICC model was also compared with recent experimental critical current data at 77 K and was found to match best using a low friction coefficient of 0.02 indicating that the tapes within the cable freely slide with respect to each other

Detection of Local Temperature Change on HTS Cables via Time-Frequency Domain Reflectometry

NASA Astrophysics Data System (ADS)

Bang, Su Sik; Lee, Geon Seok; Kwon, Gu-Young; Lee, Yeong Ho; Ji, Gyeong Hwan; Sohn, Songho; Park, Kijun; Shin, Yong-June

2017-07-01

High temperature superconducting (HTS) cables are drawing attention as transmission and distribution cables in future grid, and related researches on HTS cables have been conducted actively. As HTS cables have come to the demonstration stage, failures of cooling systems inducing quench phenomenon of the HTS cables have become significant. Several diagnosis of the HTS cables have been developed but there are still some limitations of the experimental setup. In this paper, a non-destructive diagnostic technique for the detection of the local temperature change point is proposed. Also, a simulation model of HTS cables with a local temperature change point is suggested to verify the proposed diagnosis. The performance of the diagnosis is checked by comparative analysis between the proposed simulation results and experiment results of a real-world HTS cable. It is expected that the suggested simulation model and diagnosis will contribute to the commercialization of HTS cables in the power grid.

High-performance dc SQUIDs with submicrometer niobium Josephson junctions

NASA Astrophysics Data System (ADS)

de Waal, V. J.; Klapwijk, T. M.; van den Hamer, P.

1983-11-01

We report on the fabrication and performance of low-noise, all-niobium, thin-film planar dc SQUIDs with submicrometer Josephson junctions. The junctions are evaporated obliquely through a metal shadow evaporation mask, which is made using optical lithography with 0.5 µm tolerance. The Josephson junction barrier is formed by evaporating a thin silicon film and with a subsequent oxidation in a glow discharge. The junction parameters can be reproduced within a factor of two. Typical critical currents of the SQUIDs are about 3 µA and the resistances are about 100 Ω. With SQUIDs having an inductance of 1 nH the voltage modulation is at least 60 µV. An intrinsic energy resolution of 4×10-32 J/Hz has been reached. The SQUIDs are coupled to wire-wound input coils or with thin-film input coils. The thin-film input coil consists of a niobium spiral of 20 turns on a separate substrate. In both cases the coil is glued onto a 2-nH SQUID with a coupling efficiency of at least 0.5. Referred to the thin-film input coil, the best coupled energy resolution achieved is 1.2×10-30 J/Hz measured in a flux-locked loop at frequencies above 10 Hz. As far as we know, this is the best figure achieved with an all-refractory-metal thin-film SQUID. The fabrication technique used is suited for making circuits with SQUID and pickup coil on the same substrate. We describe a compact, planar, first-order gradiometer integrated with a SQUID on a single substrate. The gradient noise of this device is 3×10-12 T m-1. The gradiometer has a size of 12 mm×17 mm, is simple to fabricate, and is suitable for biomedical applications.

Improved Sensing Coils for SQUIDs

NASA Technical Reports Server (NTRS)

Penanen, Konstantin; Hahn, Inseob; Eom, Byeong Ho

2007-01-01

An improvement in the design and fabrication of sensing coils of superconducting quantum interference device (SQUID) magnetometers has been proposed to increase sensitivity. It has been estimated that, in some cases, it would be possible to increase sensitivity by about half or to reduce measurement time correspondingly. The pertinent aspects of the problems of design and fabrication can be summarized as follows: In general, to increase the sensitivity of a SQUID magnetometer, it is necessary to maximize the magnetic flux enclosed by the sensing coil while minimizing the self-inductance of this coil. It is often beneficial to fabricate the coil from a thicker wire to reduce its self-inductance. Moreover, to optimize the design of the coil with respect to sensitivity, it may be necessary to shape the wire to other than a commonly available circular or square cross-section. On the other hand, it is not practical to use thicker superconducting wire for the entire superconducting circuit, especially if the design of a specific device requires a persistent-current loop enclosing a remotely placed SQUID sensor. It may be possible to bond a thicker sensing-coil wire to thinner superconducting wires leading to a SQUID sensor, but it could be difficult to ensure reliable superconducting connections, especially if the bonded wires are made of different materials. The main idea is to mold the sensing coil in place, to more nearly optimum cross sectional shape, instead of making the coil by winding standard pre-fabricated wire. For this purpose, a thin superconducting wire loop that is an essential part of the SQUID magnetometer would be encapsulated in a form that would serve as a mold. A low-melting-temperature superconducting metal (e.g., indium, tin, or a lead/tin alloy) would be melted into the form, which would be sized and shaped to impart the required cross section to the coil thus formed.

Flux Noise due to Spins in SQUIDs

NASA Astrophysics Data System (ADS)

LaForest, Stephanie

Superconducting Quantum Interference Devices (SQUIDs) are currently being used as flux qubits and read-out detectors in a variety of solid-state quantum computer architectures. The main limitation of SQUID qubits is that they have a coherence time of the order of 10 micros, due to the presence of intrinsic flux noise that is not yet fully understood. The origin of flux noise is currently believed to be related to spin impurities present in the materials and interfaces that form the device. Here we present a novel numerical method that enables calculations of the flux produced by spin impurities even when they are located quite close to the SQUID wire. We show that the SQUID will be particularly sensitive to spins located at its wire edges, generating flux shifts of up to 4 nano flux quanta, much higher than previous calculations based on the software package FastHenry. This shows that spin impurities in a particular region along the wire's surface play a much more important role in producing flux noise than other spin impurities located elsewhere in the device.

SQUIDs in biomagnetism: a roadmap towards improved healthcare

NASA Astrophysics Data System (ADS)

Körber, Rainer; Storm, Jan-Hendrik; Seton, Hugh; Mäkelä, Jyrki P.; Paetau, Ritva; Parkkonen, Lauri; Pfeiffer, Christoph; Riaz, Bushra; Schneiderman, Justin F.; Dong, Hui; Hwang, Seong-min; You, Lixing; Inglis, Ben; Clarke, John; Espy, Michelle A.; Ilmoniemi, Risto J.; Magnelind, Per E.; Matlashov, Andrei N.; Nieminen, Jaakko O.; Volegov, Petr L.; Zevenhoven, Koos C. J.; Höfner, Nora; Burghoff, Martin; Enpuku, Keiji; Yang, S. Y.; Chieh, Jen-Jei; Knuutila, Jukka; Laine, Petteri; Nenonen, Jukka

2016-11-01

-to-noise ratio (SNR) is low compared with high-field MRI. Realistic solutions to this problem are proposed, including implementing sensors with a noise level of 0.1 fT Hz-1/2. A logical and exciting prospect (chapter 5) is to combine MEG and ULF MRI into a single system in which both signal sources are detected with the same array of SQUIDs. A prototype system is described. The combination of MEG and ULF MRI allows one to obtain structural images of the head concurrently with the recording of brain activity. Since all MEG images require an MRI to determine source locations underlying the MEG signal, the combined modality would give a precise registration of the two images; the combination of MEG with high-field MRI can produce registration errors as large as 5 mm. The use of multiple sensors for ULF MRI increases both the SNR and the field of view. Chapter 6 describes another potentially far-reaching application of ULF MRI, namely neuronal current imaging (NCI) of the brain. Currently available neuronal imaging techniques include MEG, which is fast but has relatively poor spatial resolution, perhaps 10 mm, and functional MRI (fMRI) which has a millimeter resolution but is slow, on the order of seconds, and furthermore does not directly measure neuronal signals. NCI combines the ability of direct measurement of MEG with the spatial precision of MRI. In essence, the magnetic fields generated by neural currents shift the frequency of the magnetic resonance signal at a location that is imaged by the three-dimensional magnetic field gradients that form the basis of MRI. The currently achieved sensitivity of NCI is not quite sufficient to realize its goal, but it is close. The realization of NCI would represent a revolution in functional brain imaging. Improved techniques for immunoassay are always being sought, and chapter 7 introduces an entirely new topic, magnetic nanoparticles for immunoassay. These particles are bio-funtionalized, for example with a specific antibody which binds

HTS thin films: Passive microwave components and systems integration issues

DOE Office of Scientific and Technical Information (OSTI.GOV)

Miranda, F.A.; Chorey, C.M.; Bhasin, K.B.

1994-12-31

The excellent microwave properties of the High-Temperature-Superconductors (HTS) have been amply demonstrated in the laboratory by techniques such as resonant cavity, power transmission and microstrip resonator measurements. The low loss and high Q passive structures made possible with HTS, present attractive options for applications in commercial, military and space-based systems. However, to readily insert HTS into these systems improvement is needed in such areas as repeatability in the deposition and processing of the HTS films, metal-contact formation, wire bonding, and overall film endurance to fabrication and assembly procedures. In this paper we present data compiled in our lab which illustratemore » many of the problems associated with these issues. Much of this data were obtained in the production of a space qualified hybrid receiver-downconverter module for the Naval Research Laboratory`s High Temperature Superconductivity Space Experiment II (HTSSE-II). Examples of variations observed in starting films and finished circuits will be presented. It is shown that under identical processing the properties of the HTS films can degrade to varying extents. Finally, we present data on ohmic contacts and factors affecting their adhesion to HTS films, strength of wire bonds made to such contacts, and aging effects.« less

Recent Progress in Electrical Insulation Techniques for HTS Power Apparatus

NASA Astrophysics Data System (ADS)

Hayakawa, Naoki; Kojima, Hiroki; Hanai, Masahiro; Okubo, Hitoshi

This paper describes the electrical insulation techniques at cryogenic temperatures, i.e. Cryodielectrics, for HTS power apparatus, e.g. HTS power transmission cables, transformers, fault current limiters and SMES. Breakdown and partial discharge characteristics are discussed for different electrical insulation configurations of LN2, sub-cooled LN2, solid, vacuum and their composite insulation systems. Dynamic and static insulation performances with and without taking account of quench in HTS materials are also introduced.

Superconducting Digital Multiplexers for Sensor Arrays

NASA Technical Reports Server (NTRS)

Kadin, Alan M.; Brock, Darren K.; Gupta, Deepnarayan

2004-01-01

Arrays of cryogenic microbolometers and other cryogenic detectors are being developed for infrared imaging. If the signal from each sensor is amplified, multiplexed, and digitized using superconducting electronics, then this data can be efficiently read out to ambient temperature with a minimum of noise and thermal load. HYPRES is developing an integrated system based on SQUID amplifiers, a high-resolution analog-to-digital converter (ADC) based on RSFQ (rapid single flux quantum) logic, and a clocked RSFQ multiplexer. The ADC and SQUIDs have already been demonstrated for other projects, so this paper will focus on new results of a digital multiplexer. Several test circuits have been fabricated using Nb Josephson technology and are about to be tested at T = 4.2 K, with a more complete prototype in preparation.

Negative inductance SQUID qubit operating in a quantum regime

NASA Astrophysics Data System (ADS)

Liu, W. Y.; Su, F. F.; Xu, H. K.; Li, Z. Y.; Tian, Ye; Zhu, X. B.; Lu, Li; Han, Siyuan; Zhao, S. P.

2018-04-01

Two-junction SQUIDs with negative mutual inductance between their two arms, called nSQUIDs, have been proposed for significantly improving quantum information transfer but their quantum nature has not been experimentally demonstrated. We have designed, fabricated, and characterized superconducting nSQUID qubits. Our results provide clear evidence of the quantum coherence of the device, whose properties are well described by theoretical calculations using parameters determined from spectroscopic measurement. In addition to their future application for fast quantum information transfer, the nSQUID qubits exhibit rich characteristics in their tunable two-dimensional (2D) potentials, energy levels, wave function symmetries, and dipole matrix elements, which are essential to the study of a wide variety of macroscopic quantum phenomena such as tunneling in 2D potential landscapes.

BabySQUID: A mobile, high-resolution multichannel magnetoencephalography system for neonatal brain assessment

NASA Astrophysics Data System (ADS)

Okada, Yoshio; Pratt, Kevin; Atwood, Christopher; Mascarenas, Anthony; Reineman, Richard; Nurminen, Jussi; Paulson, Douglas

2006-02-01

We developed a prototype of a mobile, high-resolution, multichannel magnetoencephalography (MEG) system, called babySQUID, for assessing brain functions in newborns and infants. Unlike electroencephalography, MEG signals are not distorted by the scalp or the fontanels and sutures in the skull. Thus, brain activity can be measured and localized with MEG as if the sensors were above an exposed brain. The babySQUID is housed in a moveable cart small enough to be transported from one room to another. To assess brain functions, one places the baby on the bed of the cart and the head on its headrest with MEG sensors just below. The sensor array consists of 76 first-order axial gradiometers, each with a pickup coil diameter of 6mm and a baseline of 30mm, in a high-density array with a spacing of 12-14mm center-to-center. The pickup coils are 6±1mm below the outer surface of the headrest. The short gap provides unprecedented sensitivity since the scalp and skull are thin (as little as 3-4mm altogether) in babies. In an electromagnetically unshielded room in a hospital, the field sensitivity at 1kHz was ˜17fT/√Hz. The noise was reduced from ˜400to200fT/√Hz at 1Hz using a reference cancellation technique and further to ˜40fT/√Hz using a gradient common mode rejection technique. Although the residual environmental magnetic noise interfered with the operation of the babySQUID, the instrument functioned sufficiently well to detect spontaneous brain signals from babies with a signal to noise ratio (SNR) of as much as 7.6:1. In a magnetically shielded room, the field sensitivity was 17fT/√Hz at 20Hz and 30fT/√Hz at 1Hz without implementation of reference or gradient cancellation. The sensitivity was sufficiently high to detect spontaneous brain activity from a 7month old baby with a SNR as much as 40:1 and evoked somatosensory responses with a 50Hz bandwidth after as little as four averages. We expect that both the noise and the sensor gap can be reduced further by

Designing a Microhydraulically driven Mini robotic Squid

DTIC Science & Technology

2016-05-20

applications for microrobots include remote monitoring, surveillance, search and rescue, nanoassembly, medicine, and in-vivo surgery . Robotics platforms...Secretary of Defense for Research and Engineering. Designing a Microhydraulically-driven Mini- robotic Squid by Kevin Dehan Meng B.S., U.S. Air...Committee on Graduate Students 2 Designing a Microhydraulically-driven Mini- robotic Squid by Kevin Dehan Meng Submitted to the Department

High-T(sub c) squid application in medicine and geophysics

NASA Technical Reports Server (NTRS)

Polushkin, V. N.; Uchaikin, S. V.; Vasiliev, B. V.

1990-01-01

In the Laboratory a high-T(sub c) one-hole squid was built from Y1Ba2Cu3O(7-x) ceramics obtained by a standard procedure of solid state reaction. The ceramics with critical current density J(sub c) is greater than 100 A/sq cm was selected. In the middle of 10 x 10 x 2 mm ceramics pellet a 0.8 mm hole was drilled in which superconducting loop of the squid was located. Between the hole and the edge of the pellet a cut was mechanically filed out with a bridge inside it connecting the superconducting ring. A scheme of the magnetometer is presented. The resonant frequency shift of the tank circuit, the connection of the squid with this circuit, and the squid inductance are evaluated. One of the most interesting fields of the squid-based magnetometer application is biomagnetism, particularly, the human heart magnetocardiogram measuring. The low-temperature squids were used in this area and many interesting and important scientific results have been obtained. The observations have shown that the main noise contribution was not due to the squid but to the Earth's magnetic field variations, industrial inductions, and mainly to the vibrations caused by liquid nitrogen boiling and by vibrations of the box. Further attempts are needed to reduce the magnetic noise inductions. Nevertheless, the estimations promise the maximum signal/noise relation of the high-T(sub c) squid-magnetocardiometer to be not less than 10:1 in a bandwidth of 60 Hz. Apparently, such resolution would be enough not only for steady cardiogram reading but even for thin structure investigation at average technique application.

SQUID amplifiers for axion search experiments

NASA Astrophysics Data System (ADS)

Matlashov, Andrei; Schmelz, Matthias; Zakosarenko, Vyacheslav; Stolz, Ronny; Semertzidis, Yannis K.

2018-04-01

In the experiments for dark-matter QCD-axion searches, very weak microwave signals from a low-temperature High-Q resonant cavity should be detected using the highest sensitivity. The best commercial low-noise cryogenic semiconductor amplifiers based on high electron mobility transistors have a lowest noise temperature above 1.0 K, even if they are cooled well below 1 K. Superconducting quantum interference devices can work as microwave amplifiers with temperature noise close to the standard quantum limit. Previous SQUID-based RF amplifiers designed for axion search experiments have a microstrip resonant input coil and are thus called micro-strip SQUID amplifiers or MSAs. Due to the resonant input coupling they usually have narrow bandwidth. In this paper we report on a SQUID-based wideband microwave amplifier fabricated using sub-micron size Josephson junctions with very low capacitance. A single amplifier can be used in a frequency range of approximately 1-5 GHz.

Microwave signal-processing applications of HTS films

NASA Astrophysics Data System (ADS)

Adam, J. D.; Wagner, G. R.

1990-01-01

The low surface resistance (Rs) of high-temperature superconductors (HTS) will lead to the development of passive microwave devices for application in radar, electronic warfare, and satellite systems with performance significantly better than achieved with normal conductors. In particular, delay line based devices such as phase shifters, convolvers, and correlators will have low lossses and multi-GHz bandwidths. Low-loss filters which presently occupy cubic feet in waveguide will be fabricated in compact microstrip or stripline, and ultra-high Q resonators which currently require liquid helium refrigeration will be operated at around 77 K. Measurement of Rs of HTS is important both for device design and for optimization of the film growth process. Several approaches have been developed which provide data over a wide range of frequency and temperature, including stripline, cacity, and dielectric resonator techniques. HTS films for microwave applications should have at least Rs(HTS(

Trophic niche of squids: Insights from isotopic data in marine systems worldwide

NASA Astrophysics Data System (ADS)

Navarro, Joan; Coll, Marta; Somes, Christoper J.; Olson, Robert J.

2013-10-01

Cephalopods are an important prey resource for fishes, seabirds, and marine mammals, and are also voracious predators on crustaceans, fishes, squid and zooplankton. Because of their high feeding rates and abundance, squids have the potential to exert control on the recruitment of commercially important fishes. In this review, we synthesize the available information for two intrinsic markers (δ15N and δ13C isotopic values) in squids for all oceans and several types of ecosystems to obtain a global view of the trophic niches of squids in marine ecosystems. In particular, we aimed to examine whether the trophic positions and trophic widths of squid species vary among oceans and ecosystem types. To correctly compare across systems, we adjusted squid δ15N values for the isotopic variability of phytoplankton at the base of the food web provided by an ocean circulation-biogeochemistry-isotope model. Studies that focused on the trophic ecology of squids using isotopic techniques were few, and most of the information on squids was from studies on their predators. Our results showed that squids occupy a large range of trophic positions and exploit a large range of trophic resources, reflecting the versatility of their feeding behavior and confirming conclusions from food-web models. Clear differences in both trophic position and trophic width were found among oceans and ecosystem types. The study also reinforces the importance of considering the natural variation in isotopic values when comparing the isotopic values of consumers inhabiting different ecosystems.

SQUIDs De-fluxing Using a Decaying AC Magnetic Field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matlashov, Andrei Nikolaevich; Semenov, Vasili Kirilovich; Anderson, Bill

Flux trapping is the Achilles’ heel of all superconductor electronics. The most direct way to avoid flux trapping is a prevention of superconductor circuits from exposure to magnetic fields. Unfortunately this is not feasible if the circuits must be exposed to a strong DC magnetic field even for a short period of time. For example, such unavoidable exposures take place in superparamagnetic relaxation measurements (SPMR) and ultra-low field magnetic resonance imaging (ULF MRI) using unshielded thin-film SQUID-based gradiometers. Unshielded SQUIDs stop working after being exposed to DC magnetic fields of only a few Gauss in strength. In this paper wemore » present experimental results with de-fluxing of planar thin-film LTS SQUID-based gradiometers using a strong decaying AC magnetic field. We used four commercial G136 gradiometers for SPMR measurements with up to a 10 mT magnetizing field. Strong 12.9 kHz decaying magnetic field pulses reliably return SQUIDs to normal operation 50 ms after zeroing the DC magnetizing field. This new AC de-fluxing method was also successfully tested with seven other different types of LTS SQUID sensors and has been shown to dissipate extremely low energy.« less

Analogue Hawking radiation in a dc-SQUID array transmission line.

PubMed

Nation, P D; Blencowe, M P; Rimberg, A J; Buks, E

2009-08-21

We propose the use of a superconducting transmission line formed from an array of direct-current superconducting quantum interference devices for investigating analogue Hawking radiation. Biasing the array with a space-time varying flux modifies the propagation velocity of the transmission line, leading to an effective metric with a horizon. Being a fundamentally quantum mechanical device, this setup allows for investigations of quantum effects such as backreaction and analogue space-time fluctuations on the Hawking process.

Rotor compound concept for designing an industrial HTS synchronous motor

NASA Astrophysics Data System (ADS)

Kashani, M.; Hosseina, M.; Sarrafan, K.; Darabi, A.

2013-06-01

Recently, producing power with smaller amount of losses become as a goal in our daily life. Today, large amount of energy waste in power networks all around the world. The main reason is “resistive electric equipments” of power networks. Since early 1980s, simultaneous with the development of high temperature superconductive (HTS) technology, superconductors gently attracted the mankind attentions. Using superconductive equipments instead of conventional resistive ones are result in salient electric loss reduction in power systems. Especially to reduce losses in power networks superconductive industrial rotating machines can potentially perform a significant role. In early recent century, first generation of HTS rotating machines was born. But unfortunately they have long way to penetrate the commercial markets yet. In HTS rotating machines the conventional copper made windings are replaced with the HTS superconductors. In this paper an industrial HTS synchronous motor with YBCO coated conductor field windings was designed. As a new approach, model was equipped with a compound rotor that includes both magnetic and non-magnetic materials. So, large amount of heavy iron made part was replaced by light non-magnetic material such as G-10 fiberglass. Furthermore, in this structure iron loss in rotor could be reduced to its lowest value. Also less weight and more air gap energy density were the additional advantages. Regarding zero electric loss production in field windings and less iron loss in rotor construction, this model potentially is more effective than the other iron made HTS motors.

Compact cryocooling system for HTS sampler

NASA Astrophysics Data System (ADS)

Suzuki, H.; Maruyama, M.; Hato, T.; Wakana, H.; Tanabe, K.; Konno, T.; Uekusa, K.; Sato, N.; Kawabata, M.

2007-10-01

This paper describes a compact cooling system using a single-stage stirling-type cryocooler for a practical HTS sampler. The system was designed to cool down an HTS sampler module below 50 K, enabling a bandwidth of the chip more than 100 GHz. The system measures 150 mm in width, 140 mm in height and 310 mm in depth, and weighs 5 kg. Semi-rigid coaxial cables made of brass with a silver coated inner conductor were adopted for a signal to be measured and a trigger pulse. The loss for the signal line was less than 1.5 dB at 50 GHz with relatively small thermal inflow. Thermal inflows from low frequency lines, IF signal lines for control/output of the sampler and dc bias lines, were minimized by choosing proper wires. A new sampler module with reduced weight was placed on the cold stage, which was surrounded by double magnetic shields. The module was successfully cooled down to less than 50 K with cooling time of 1 h in the system. We have also succeeded in observing sinusoidal waveforms with the HTS sampler cooled by the compact cooling system.

Mismatch between the eye and the optic lobe in the giant squid.

PubMed

Liu, Yung-Chieh; Liu, Tsung-Han; Yu, Chun-Chieh; Su, Chia-Hao; Chiao, Chuan-Chin

2017-07-01

Giant squids ( Architeuthis ) are a legendary species among the cephalopods. They live in the deep sea and are well known for their enormous body and giant eyes. It has been suggested that their giant eyes are not adapted for the detection of either mates or prey at distance, but rather are best suited for monitoring very large predators, such as sperm whales, at distances exceeding 120 m and at a depth below 600 m (Nilsson et al. 2012 Curr. Biol. 22 , 683-688. (doi:10.1016/j.cub.2012.02.031)). However, it is not clear how the brain of giant squids processes visual information. In this study, the optic lobe of a giant squid ( Architeuthis dux , male, mantle length 89 cm), which was caught by local fishermen off the northeastern coast of Taiwan, was scanned using high-resolution magnetic resonance imaging in order to examine its internal structure. It was evident that the volume ratio of the optic lobe to the eye in the giant squid is much smaller than that in the oval squid ( Sepioteuthis lessoniana ) and the cuttlefish ( Sepia pharaonis ). Furthermore, the cell density in the cortex of the optic lobe is significantly higher in the giant squid than in oval squids and cuttlefish, with the relative thickness of the cortex being much larger in Architeuthis optic lobe than in cuttlefish. This indicates that the relative size of the medulla of the optic lobe in the giant squid is disproportionally smaller compared with these two cephalopod species. This morphological study of the giant squid brain, though limited only to the optic lobe, provides the first evidence to support that the optic lobe cortex, the visual information processing area in cephalopods, is well developed in the giant squid. In comparison, the optic lobe medulla, the visuomotor integration centre in cephalopods, is much less developed in the giant squid than other species. This finding suggests that, despite the giant eye and a full-fledged cortex within the optic lobe, the brain of giant

Read-out electronics for DC squid magnetic measurements

DOEpatents

Ganther, Jr., Kenneth R.; Snapp, Lowell D.

2002-01-01

Read-out electronics for DC SQUID sensor systems, the read-out electronics incorporating low Johnson noise radio-frequency flux-locked loop circuitry and digital signal processing algorithms in order to improve upon the prior art by a factor of at least ten, thereby alleviating problems caused by magnetic interference when operating DC SQUID sensor systems in magnetically unshielded environments.

Magnetic biosensor using a high transition temperature SQUID

NASA Astrophysics Data System (ADS)

Grossman, Helene Lila

A high transition temperature (Tc) Superconducting QUantum Interference Device (SQUID) is used to detect magnetically-labeled microorganisms. The targets are identified and quantified by means of magnetic relaxation measurements, with no need for unbound magnetic labels to be washed away. The binding rate between antibody-linked magnetic particles and targets can be measured with this technique. Installed in a "SQUID microscope," a YBa2Cu 3O7-delta SQUID is mounted on a sapphire rod thermally linked to a liquid nitrogen can; these components are enclosed in a fiberglass vacuum chamber. A thin window separates the vacuum chamber from the sample, which is at room temperature and atmospheric pressure. In one mode of the experiment, targets are immobilized on a substrate and immersed a suspension of ˜50 nm diameter superparamagnetic particles, coated with antibodies. A pulsed magnetic field aligns the magnetic dipole moments, and the SQUID measures the magnetic relaxation signal each time the field is turned off. Unbound particles relax within ˜50 mus by Brownian rotation, too fast for the SQUID system to measure. In contrast, particles bound to targets have their Brownian motion inhibited. These particles relax in ˜1 s by rotation of the internal dipole moment, and this Neel relaxation process is detected by the SQUID. This assay is demonstrated with a model system of liposomes carrying the FLAG epitope; the detection limit is (2.7 +/- 0.2) x 105 particles. The replacement of the SQUID with a gradiometer improves the detection limit to (7.0 +/- 0.7) x 103 particles. In an alternate mode of the experiment, freely suspended targets (larger than ˜1 mum diameter) are detected. Since the Brownian relaxation time of the targets is longer than the measurement time, particles bound to targets are effectively immobilized and exhibit Neel relaxation. Listeria monocytogenes are detected using this method; the sensitivity is (1.1 +/- 0.2) x 105 bacteria in 20 muL. For a 1 n

Characteristics on electodynamic suspension simulator with HTS levitation magnet

NASA Astrophysics Data System (ADS)

Lee, J.; Bae, D. K.; Sim, K.; Chung, Y. D.; Lee, Y.-S.

2009-10-01

High- Tc superconducting (HTSC) electrodynamic suspension (EDS) system basically consists of the HTSC levitation magnet and the ground conductor. The levitation force of EDS system is forms by the interaction between the moving magnetic field produced by the onboard levitation magnet and the induced magnetic field produced by eddy current in the ground conductor. This paper deals with the characteristics of the EDS simulators with high- Tc superconducting (HTS) levitation magnet. Two EDS simulator systems, rotating type EDS simulator and static type EDS simulator, were studied in this paper. The rotating type EDS simulator consists of a HTS levitation magnet and a 1.5 m diameter rotating ground conductor, a motor, the supporting structure and force measuring devices. In the static type EDS simulator, instead of moving magnetic field, AC current was applied to the fixed HTS levitation magnet to induce the eddy current. The static type EDS simulator consists of a HTS levitation magnet, a ground conductor, force measuring devices and supporting structure. The double-pancake type HTSC levitation magnet was designed, manufactured and tested in the EDS simulator.

[Biochemistry and functional characterization of squid mantle meat (Dosidicus gigas)].

PubMed

Abugoch, L; Guarda, A; María Pérez, L; Isabel Donghi, M

2000-12-01

A study for the characterization of frozen giant squid mantle (meat) protein stored at -25 degrees C for 8 month was started. In the present research, the following functional properties were investigate: emulsifying, water holding and gel forming capacities. Optimal conditions for the separation and differentiation of miofibrillar and sarcoplasmatic proteins were also studied. It was found that the unfrozen giant squid mantle meat es capable of emulifying 2.817,4 g of oil/g of protein and holding capacity was 3.64 g of water/g of protein. Related to the gel forming capacity, it was not obtain, probably due to excessive storage of the meat. With regard to miofibrilar protein obtention of the squid mantle meat, it was found that two low ionic strength washings (I = 0.05), the sarcoplasmic proteins were practically eliminated from the protein matrix. The differentiation of miofibrilar and sarcoplasmatic proteins was obtained by PAGE-SDS of the squid mantle meat extracted at two different ionic strength (I = 0.05 and I = 0.5). This work demonstrates that the giant squid mantle protein has a high emulsifying and water holding capacity, and it can be used, as a raw material, for the improvement of sausage products. About the gelling products, more studies will be necessary with fresh squid mantle meat to conclude about this functional property.

Demonstration of a scalable frequency-domain readout of metallic magnetic calorimeters by means of a microwave SQUID multiplexer

NASA Astrophysics Data System (ADS)

Kempf, Sebastian; Wegner, Mathias; Fleischmann, Andreas; Gastaldo, Loredana; Herrmann, Felix; Papst, Maximilian; Richter, Daniel; Enss, Christian

2017-01-01

We report on the first demonstration of a scalable GHz frequency-domain readout of metallic magnetic calorimeters (MMCs) using a 64 pixel detector array that is read out by an integrated, on-chip microwave SQUID multiplexer. The detector array is optimized for detecting soft X-ray photons and the multiplexer is designed to provide a signal rise time τrise<400 ns and an intrinsic energy sensitivity ɛ <30 h . This results in an expected energy resolution Δ EFWHM <10 eV . We measured a signal rise time τrise as low as 90 ns and an energy resolution Δ EFWHM as low as 50 eV for 5.9 keV photons. The rise time is about an order of magnitude faster compared to other multiplexed low-temperature microcalorimeters and close to the intrinsic value set by the coupling between electron and spins. The energy resolution is degraded with respect to our design value due to a rather low intrinsic quality factor of the microwave resonators that is caused by the quality of the Josephson junction of the associated rf-SQUID as well as an elevated chip temperature as compared to the heat bath. Though the achieved energy resolution is not yet compatible with state-of-the-art single-channel MMCs, this demonstration of a scalable readout approach for MMCs in combination with the full understanding of the device performance showing ways how to improve represents an important milestone for the development of future large-scale MMC detector arrays.

Technical and commerical challenges in high Tc SQUIDs and their industrial applications

NASA Technical Reports Server (NTRS)

Lu, D. F.

1995-01-01

A SQUID is the most sensitive device for measuring changes in magnetic flux. Since its discovery in the sixties, scientists have made consistent efforts to apply SQUID's to various applications. Instruments that are the most sensitive in their respective categories have been built, such as SQUID DC susceptometer that is now manufactured by Quantum Design, pico-voltmeter which could measure 10(exp -14) volts, and gravitational wave detectors. One of the most successful applications of SQUID's is in magnetoencephalography, a non-invasive technique for investigating neuronal activity in the living human brain. This technique employs a multi-channel SQUID magnetometer that maps the weak magnetic field generated by small current when information is processed in brain, and its performance is marvelous.

Current-induced SQUID behavior of superconducting Nb nano-rings

NASA Astrophysics Data System (ADS)

Sharon, Omri J.; Shaulov, Avner; Berger, Jorge; Sharoni, Amos; Yeshurun, Yosef

2016-06-01

The critical temperature in a superconducting ring changes periodically with the magnetic flux threading it, giving rise to the well-known Little-Parks magnetoresistance oscillations. Periodic changes of the critical current in a superconducting quantum interference device (SQUID), consisting of two Josephson junctions in a ring, lead to a different type of magnetoresistance oscillations utilized in detecting extremely small changes in magnetic fields. Here we demonstrate current-induced switching between Little-Parks and SQUID magnetoresistance oscillations in a superconducting nano-ring without Josephson junctions. Our measurements in Nb nano-rings show that as the bias current increases, the parabolic Little-Parks magnetoresistance oscillations become sinusoidal and eventually transform into oscillations typical of a SQUID. We associate this phenomenon with the flux-induced non-uniformity of the order parameter along a superconducting nano-ring, arising from the superconducting leads (‘arms’) attached to it. Current enhanced phase slip rates at the points with minimal order parameter create effective Josephson junctions in the ring, switching it into a SQUID.

Squid as nutrient vectors linking Southwest Atlantic marine ecosystems

NASA Astrophysics Data System (ADS)

Arkhipkin, Alexander I.

2013-10-01

Long-term investigations of three abundant nektonic squid species from the Southwest Atlantic, Illex argentinus, Doryteuthis gahi and Onykia ingens, permitted to estimate important population parameters including individual growth rates, duration of ontogenetic phases and mortalities. Using production model, the productivity of squid populations at different phases of their life cycle was assessed and the amount of biomass they convey between marine ecosystems as a result of their ontogenetic migrations was quantified. It was found that squid are major nutrient vectors and play a key role as transient 'biological pumps' linking spatially distinct marine ecosystems. I. argentinus has the largest impact in all three ecosystems it encounters due to its high abundance and productivity. The variable nature of squid populations increases the vulnerability of these biological conveyers to overfishing and environmental change. Failure of these critical biological pathways may induce irreversible long-term consequences for biodiversity, resource abundance and spatial availability in the world ocean.

Vampire squid: detritivores in the oxygen minimum zone.

PubMed

Hoving, Hendrik J T; Robison, Bruce H

2012-11-22

Vampire squid (Vampyroteuthis infernalis) are considered phylogenetic relics with cephalopod features of both octopods and squids. They lack feeding tentacles, but in addition to their eight arms, they have two retractile filaments, the exact functions of which have puzzled scientists for years. We present the results of investigations on the feeding ecology and behaviour of Vampyroteuthis, which include extensive in situ, deep-sea video recordings from MBARI's remotely operated vehicles (ROVs), laboratory feeding experiments, diet studies and morphological examinations of the retractile filaments, the arm suckers and cirri. Vampire squid were found to feed on detrital matter of various sizes, from small particles to larger marine aggregates. Ingested items included the remains of gelatinous zooplankton, discarded larvacean houses, crustacean remains, diatoms and faecal pellets. Both ROV observations and laboratory experiments led to the conclusion that vampire squid use their retractile filaments for the capture of food, supporting the hypothesis that the filaments are homologous to cephalopod arms. Vampyroteuthis' feeding behaviour is unlike any other cephalopod, and reveals a unique adaptation that allows these animals to spend most of their life at depths where oxygen concentrations are very low, but where predators are few and typical cephalopod food is scarce.

Sensitive Spin Detection Using An On-Chip Squid-Waveguide Resonator

NASA Astrophysics Data System (ADS)

Yue, Guang

Quantum computing gives novel way of computing using quantum mechanics, which furthers human knowledge and has exciting applications. Quantum systems with diluted spins such as rare earth ions hosted in single crystal, molecule-based magnets etc. are promising qubits candidates to form the basis of a quantum computer. High sensitivity measurement and coherent control of these spin systems are crucial for their practical usage as qubits. The micro-SQUID (direct-current micrometer-sized Superconducting QUantum Interference Device) is capable to measure magnetization of spin system with high sensitivity. For example, the micro-SQUID technique can measure magnetic moments as small as several thousand muB as shown by the study of [W. Wernsdorfer, Supercond. Sci. Technol. 22, 064013 (2009)]. Here we develop a novel on-chip setup that combines the micro-SQUID sensitivity with microwave excitation. Such setup can be used for electron spin resonance measurements or coherent control of spins utilizing the high sensitivity of micro-SQUID for signal detection. To build the setup, we studied the fabrication process of the micro-SQUID, which is made of weak-linked Josephson junctions. The SQUID as a detector is integrated on the same chip with a shorted coplanar waveguide, so that the microwave pulses can be applied through the waveguide to excite the sample for resonance measurements. The whole device is plasma etched from a thin (˜ 20nm) niobium film, so that the SQUID can work at in large in-plane magnetic fields of several tesla. In addition, computer simulations are done to find the best design of the waveguide such that the microwave excitation field is sufficiently strong and uniformly applied to the sample. The magnetization curve of Mn12 molecule-based magnet sample is measured to prove the proper working of the micro-SQUID. Electron spin resonance measurement is done on the setup for gadolinium ions diluted in a CaWO4 single crystal. The measurement shows clear

The pace of life in deep-dwelling squids

NASA Astrophysics Data System (ADS)

Hoving, H. J. T.; Robison, B. H.

2017-08-01

Coastal and epipelagic cephalopods are among the fastest growing invertebrates, with life cycles of typically 1 year or less. Evidence is accumulating that deep-sea taxa often live longer and grow slower than their shallow water relatives. We test the hypothesis that deep-sea squid show increased longevity and reduced growth rates compared to coastal and epipelagic species, by validation experiments and quantification of statolith increments of three deep-sea squids from the Monterey Submarine Canyon. The periodicity of statolith increment formation in coastal species is daily, but is unknown for deep-sea squid. Between 2010 and 2013, specimens of Chiroteuthis calyx, Galiteuthis phyllura and Octopoteuthis deletron were captured by remotely operated vehicles and trawl nets off California. ROV-captured living squid were immersed in tetracycline and kept alive in the lab for between 3 and 14 days. Correlating the number of elapsed days with the number of newly deposited statolith increments, and statolith growth after the fluorescent tetracycline mark, provided evidence of regular and daily increment deposition, in C. calyx and O. deletron. This relationship was less strong in G. phyllura and the one-increment-per-day hypothesis was not accepted for this species. Reconstructing growth rates based on statolith counts and wet weights from animals of a wide size range suggest that O. deletron is a slower growing squid (0.59% BW/day) than C. calyx (1.3% BW/day) and G. phyllura (1.2% BW/day). Octopoteuthis deletron matures at around two years, the oldest C. calyx was a mature male of 1.5 years and the eldest G. phyllura was 10 months and still immature. Maximum reported sizes for G. phyllura and C. calyx exceed those of our examined specimens, and therefore their longevity likely exceeds 2 years, in particular if the females brood their eggs. Our study supports the hypothesis that deeper living squid exhibit reduced growth rates and an increased longevity compared to

Design, Construction and Test of Cryogen-Free HTS Coil Structure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hocker, H.; Anerella, M.; Gupta, R.

2011-03-28

This paper will describe design, construction and test results of a cryo-mechanical structure to study coils made with the second generation High Temperature Superconductor (HTS) for the Facility for Rare Isotope Beams (FRIB). A magnet comprised of HTS coils mounted in a vacuum vessel and conduction-cooled with Gifford-McMahon cycle cryocoolers is used to develop and refine design and construction techniques. The study of these techniques and their effect on operations provides a better understanding of the use of cryogen free magnets in future accelerator projects. A cryogen-free, superconducting HTS magnet possesses certain operational advantages over cryogenically cooled, low temperature superconductingmore » magnets.« less

Tandem Repeat Proteins Inspired By Squid Ring Teeth

NASA Astrophysics Data System (ADS)

Pena-Francesch, Abdon

Proteins are large biomolecules consisting of long chains of amino acids that hierarchically assemble into complex structures, and provide a variety of building blocks for biological materials. The repetition of structural building blocks is a natural evolutionary strategy for increasing the complexity and stability of protein structures. However, the relationship between amino acid sequence, structure, and material properties of protein systems remains unclear due to the lack of control over the protein sequence and the intricacies of the assembly process. In order to investigate the repetition of protein building blocks, a recently discovered protein from squids is examined as an ideal protein system. Squid ring teeth are predatory appendages located inside the suction cups that provide a strong grasp of prey, and are solely composed of a group of proteins with tandem repetition of building blocks. The objective of this thesis is the understanding of sequence, structure and property relationship in repetitive protein materials inspired in squid ring teeth for the first time. Specifically, this work focuses on squid-inspired structural proteins with tandem repeat units in their sequence (i.e., repetition of alternating building blocks) that are physically cross-linked via beta-sheet structures. The research work presented here tests the hypothesis that, in these systems, increasing the number of building blocks in the polypeptide chain decreases the protein network defects and improves the material properties. Hence, the sequence, nanostructure, and properties (thermal, mechanical, and conducting) of tandem repeat squid-inspired protein materials are examined. Spectroscopic structural analysis, advanced materials characterization, and entropic elasticity theory are combined to elucidate the structure and material properties of these repetitive proteins. This approach is applied not only to native squid proteins but also to squid-inspired synthetic polypeptides

1 MVA HTS-2G Generator for Wind Turbines

NASA Astrophysics Data System (ADS)

Kovalev, K. L.; Poltavets, V. N.; Ilyasov, R. I.; Verzhbitsky, L. G.; Kozub, S. S.

2017-10-01

The calculation, design simulations and design performance of 1 MVA HTS-2G (second-generation high-temperature superconductor) Generator for Wind Turbines were done in 2013-2014 [1]. The results of manufacturing and testing of 1 MVA generator are presented in the article. HTS-2G field coils for the rotor were redesigned, fabricated and tested. The tests have shown critical current of the coils, 41-45 A (self field within the ferromagnetic core, T = 77 K), which corresponds to the current of short samples at self field. Application of the copper inner frame on the pole has improved internal cooling conditions of HTS coil windings and reduced the magnetic field in the area, thereby increased the critical current value. The original construction of the rotor with a rotating cryostat was developed, which decreases the thermal in-flow to the rotor. The stator of 1 MW HTS-2G generator has been manufactured. In order to improve the specific weight of the generator, the wave (harmonic drive) multiplier was used, which provides increasing RPM from 15 RPM up to 600 RPM. The total mass of the multiplier and generator is significantly smaller compared to traditional direct-drive wind turbines generators [2-7]. Parameters of the multiplier and generator were chosen based on the actual parameters of wind turbines, namely: 15 RPM, power is 1 MVA. The final test of the assembled synchronous generator with HTS-2G field coils for Wind Turbines with output power 1 MVA was completed during 2015.

Modelling of the test of the JT-60SA HTS current leads

NASA Astrophysics Data System (ADS)

Zappatore, A.; Heller, R.; Savoldi, L.; Zanino, R.

2017-07-01

The CURLEAD code, which was developed at the Karlsruhe Institute of Technology (KIT), implements an integrated 1D transient model of a high temperature superconducting (HTS) current lead (CL) including the room termination (RT), the meander-flow type heat exchanger (HX), and the HTS module. CURLEAD was successfully used for the design of the 70 kA ITER demonstrator and of the W7-X and JT-60SA CLs. Recently the code was successfully applied to the prediction and analysis of steady state operation of the ITER correction coils (CC) HTS CL. Here the steady state and pulsed operation of the JT-60SA HTS CLs are analysed, which requires also the modelling of the HX shell and of the vacuum shell, which was not present in the ITER CC. The CURLEAD model extension is presented and the capability of the new version of CURLEAD to reproduce the transient experimental data of the JT-60SA HTS CL is shown. The results obtained provide a better understanding of key parameters of the CL, among which the temperature evolution at the HX-HTS interface, the GHe mass flow rate needed in the HX to achieve the target temperature at that location and the heat load at the cold end.

Integration of HTS Cables in the Future Grid of the Netherlands

NASA Astrophysics Data System (ADS)

Zuijderduin, R.; Chevtchenko, O.; Smit, J. J.; Aanhaanen, G.; Melnik, I.; Geschiere, A.

Due to increasing power demand, the electricity grid of the Netherlands is changing. The future transmission grid will obtain electrical power generated by decentralized renewable sources, together with large scale generation units located at the coastal region. In this way electrical power has to be distributed and transmitted over longer distances from generation to end user. Potential grid issues like: amount of distributed power, grid stability and electrical loss dissipation merit particular attention. High temperature superconductors (HTS) can play an important role in solving these grid problems. Advantages to integrate HTS components at transmission voltages are numerous: more transmittable power together with less emissions, intrinsic fault current limiting capability, lower ac loss, better control of power flow, reduced footprint, less magnetic field emissions, etc. The main obstacle at present is the relatively high price of HTS conductor. However as the price goes down, initial market penetration of several HTS components (e.g.: cables, fault current limiters) is expected by year 2015. In the full paper we present selected ways to integrate EHV AC HTS cables depending on a particular future grid scenario in the Netherlands.

Use of in Vitro HTS-Derived Concentration-Response Data as ...

EPA Pesticide Factsheets

Background: Quantitative high-throughput screening (qHTS) assays are increasingly being employed to inform chemical hazard identification. Hundreds of chemicals have been tested in dozens of cell lines across extensive concentration ranges by the National Toxicology Program in collaboration with the NIH Chemical Genomics Center. Objectives: To test a hypothesis that dose-response data points of the qHTS assays can serve as biological descriptors of assayed chemicals and, when combined with conventional chemical descriptors, may improve the accuracy of Quantitative Structure-Activity Relationship (QSAR) models applied to prediction of in vivo toxicity endpoints. Methods and Results: The cell viability qHTS concentration-response data for 1,408 substances assayed in 13 cell lines were obtained from PubChem; for a subset of these compounds rodent acute toxicity LD50 data were also available. The classification k Nearest Neighbor and Random Forest QSAR methods were employed for modeling LD50 data using either chemical descriptors alone (conventional models) or in combination with biological descriptors derived from the concentration-response qHTS data (hybrid models). Critical to our approach was the use of a novel noise-filtering algorithm to treat qHTS data. We show that both the external classification accuracy and coverage (i.e., fraction of compounds in the external set that fall within the applicability domain) of the hybrid QSAR models was superior to convent

Development of a 600 kJ HTS SMES

NASA Astrophysics Data System (ADS)

Seong, K. C.; Kim, H. J.; Kim, S. H.; Sim, K. D.; Sohn, M. H.; Lee, E. Y.; Park, S. J.; Hahn, S. Y.; Park, M. W.

2008-09-01

This paper describes an overview of development on a 600 kJ high-temperature superconducting magnetic energy storage (HTS SMES). Our final goal will be the commercialization of MJ class HTS SMES system for the increase of power quality within 5 years. Hence, for this purpose, we have developed the research and development in 3 years. The purpose of this research is to develop a pilot system, which can protect the sensitivity loads from a momentary power interruption or a voltage sag.

ELECTROPHORETIC AND IMMUNOLOGICAL STUDIES OF SQUID AXOPLASM PROTEINS.

PubMed

HUNEEUS-COX, F

1964-03-06

By disc electrophoresis of the axoplasm of Dosidicus gigas, 14 protein bands have been resolved. Anti-bodies to the intra-axonal proteins and to squid blood proteins were produced in rabbits. By Ouchterlony's technique, six antigenic components can be demonstrated in axoplasm; the combined use of disc electrophoresis and immune diflusion in agar resolves seven antigenic components in axoplasm; none of these components is detectable in squid blood.

Vampire squid: detritivores in the oxygen minimum zone

PubMed Central

Hoving, Hendrik J. T.; Robison, Bruce H.

2012-01-01

Vampire squid (Vampyroteuthis infernalis) are considered phylogenetic relics with cephalopod features of both octopods and squids. They lack feeding tentacles, but in addition to their eight arms, they have two retractile filaments, the exact functions of which have puzzled scientists for years. We present the results of investigations on the feeding ecology and behaviour of Vampyroteuthis, which include extensive in situ, deep-sea video recordings from MBARI's remotely operated vehicles (ROVs), laboratory feeding experiments, diet studies and morphological examinations of the retractile filaments, the arm suckers and cirri. Vampire squid were found to feed on detrital matter of various sizes, from small particles to larger marine aggregates. Ingested items included the remains of gelatinous zooplankton, discarded larvacean houses, crustacean remains, diatoms and faecal pellets. Both ROV observations and laboratory experiments led to the conclusion that vampire squid use their retractile filaments for the capture of food, supporting the hypothesis that the filaments are homologous to cephalopod arms. Vampyroteuthis' feeding behaviour is unlike any other cephalopod, and reveals a unique adaptation that allows these animals to spend most of their life at depths where oxygen concentrations are very low, but where predators are few and typical cephalopod food is scarce. PMID:23015627

AC Application of HTS Conductors in Highly Dynamic Electric Motors

NASA Astrophysics Data System (ADS)

Oswald, B.; Best, K.-J.; Setzer, M.; Duffner, E.; Soell, M.; Gawalek, W.; Kovalev, L. K.

2006-06-01

Based on recent investigations we design highly dynamic electric motors up to 400 kW and linear motors up to 120 kN linear force using HTS bulk material and HTS tapes. The introduction of HTS tapes into AC applications in electric motors needs fundamental studies on double pancake coils under transversal magnetic fields. First theoretical and experimental results on AC field distributions in double-pancake-coils and corresponding AC losses will be presented. Based on these results the simulation of the motor performance confirms extremely high power density and efficiency of both types of electric motors. Improved characteristics of rare earth permanent magnets used in our motors at low temperatures give an additional technological benefit.

Parametric Phase-Sensitive Detector Using Two-cell SQUID

DTIC Science & Technology

2010-08-01

an attenuator of -20 dB. The microwave was fed into the coplanar resonator by a coplanar capacitance of 9 fF, and corresponding response was coupled...transmission line between the two coupled coplanar capacitances . With a network analyzer, the resonant frequency was confirmed to be 8.985 GHz and the...microwave directional sensors based on two-cell SQUIDs. Two SQUID circuits with different values of McCumber parameter βc have been tested. Observed

Centrifuge advances using HTS magnetic bearings

NASA Astrophysics Data System (ADS)

Werfel, F. N.; Flögel-Delor, U.; Rothfeld, R.; Wippich, D.; Riedel, T.

2001-05-01

Passive magnetic bearings are of increasing technical interest. We performed experiments with centrifugal rotors to analyze gyroscopic forces in terms imbalance, rotor elasticity and damping. Centrifuge rotors need to be operated soft and stable without whirling the sediments. In order to evaluate optimal parameters critical and resonance behaviors are investigated. Eccentricities up 2 mm are safely passed by accelerating test wheels. In a simple model we describe the effect of passing critical rotational speeds. Measurements of bearing properties and wheel performance are presented. We have constructed a first prototype centrifuge designed with a HTS double bearing which operates a titanium rotor safely up to 30 000 rpm. A 15 W Stirling cooler serves cryogenics of the YBCO stators. From the experiments design guidelines for centrifugal applications with HTS bearings are given.

Use of a SQUID array to detect T-cells with magnetic nanoparticles in determining transplant rejection

NASA Astrophysics Data System (ADS)

Flynn, Edward R.; Bryant, H. C.; Bergemann, Christian; Larson, Richard S.; Lovato, Debbie; Sergatskov, Dmitri A.

2007-04-01

Acute rejection in organ transplant is signaled by the proliferation of T-cells that target and kill the donor cells requiring painful biopsies to detect rejection onset. An alternative non-invasive technique is proposed using a multi-channel superconducting quantum interference device (SQUID) magnetometer to detect T-cell lymphocytes in the transplanted organ labeled with magnetic nanoparticles conjugated to antibodies specifically attached to lymphocytic ligand receptors. After a magnetic field pulse, the T-cells produce a decaying magnetic signal with a characteristic time of the order of a second. The extreme sensitivity of this technique, 10 5 cells, can provide early warning of impending transplant rejection and monitor immune-suppressive chemotherapy.

Study of Running Stability in Side-Suspended HTS-PMG Maglev Circular Line System

NASA Astrophysics Data System (ADS)

Zhou, Dajin; Zhao, Lifeng; Li, Linbo; Cui, Chenyu; Hsieh, Chang-Chun; Zhang, Yong; Guo, Jianqiang; Zhao, Yong

2017-07-01

A research on stability of the side-suspended HTS-PMG maglev circular line system is carried out through simulation experiment. The results show that the maglev vehicle will gradually get close to the track surface during acceleration under the action of centrifugal force, leading to decay of guidance force and occurrence of vertical eccentric motion. In case of linear array of YBa2Cu3O7-x (YBCO) bulks, the guidance force will be changed with the decreasing of the levitation gap. It can be suppressed through the complex arrangement of YBCO bulks. Fortunately, triangle array of YBCO bulks can effectively keep the guidance force constant and realize stable running during accelerating process of the prototype vehicle. Based on the research on stability of side-suspended maglev vehicle, a side-suspended PMG circular test track with diameter of 6.5 m and circumference of 20.4 m is successfully designed and established, enabling the prototype vehicle to run stably at up to 82.5 km/h under open atmosphere (9.6 × 104 Pa).

Identification of four squid species by quantitative real-time polymerase chain reaction.

PubMed

Ye, Jian; Feng, Junli; Liu, Shasha; Zhang, Yanping; Jiang, Xiaona; Dai, Zhiyuan

2016-02-01

Squids are distributed worldwide, including many species of commercial importance, and they are often made into varieties of flavor foods. The rapid identification methods for squid species especially their processed products, however, have not been well developed. In this study, quantitative real-time PCR (qPCR) systems based on specific primers and TaqMan probes have been established for rapid and accurate identification of four common squid species (Ommastrephes bartramii, Dosidicus gigas, Illex argentinus, Todarodes pacificus) in Chinese domestic market. After analyzing mitochondrial genes reported in GenBank, the mitochondrial cytochrome b (Cytb) gene was selected for O. bartramii detection, cytochrome c oxidase subunit I (COI) gene for D. gigas and T. Pacificus detection, ATPase subunit 6 (ATPase 6) gene for I. Argentinus detection, and 12S ribosomal RNA (12S rDNA) gene for designing Ommastrephidae-specific primers and probe. As a result, all the TaqMan systems are of good performance, and efficiency of each reaction was calculated by making standard curves. This method could detect target species either in single or mixed squid specimen, and it was applied to identify 12 squid processed products successfully. Thus, it would play an important role in fulfilling labeling regulations and squid fishery control. Copyright © 2016 Elsevier Ltd. All rights reserved.

The Effect of Magnetic Field on HTS Leads What Happens when thePower Fails at RAL?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Green, Michael A.

2007-02-14

The key to being able to operate the MICE superconducting solenoids on small coolers is the use of high temperature superconducting (HTS) leads between the first stage of the cooler and the magnet, which operates at around 4.2 K. Because MICE magnets are not shielded, all of the MICE magnets have a stray magnetic field in the region where the coolers and the HTS leads are located. The behavior of the HTS leads in a magnetic field depends strongly on the HTS material used for the leads and the temperature of the cooler first stage temperature. The HTS leads canmore » be specified to operate at the maximum current for the magnet. This report shows how the HTS leads can be specified for use the MICE magnets. MICE magnets take from 1.3 hours (the tracker solenoids) to 3.7 hours (the coupling magnet) to charge to the highest projected operating currents. If the power fails, the cooler and the upper ends of the HTS leads warm up. The question is how one can discharge the magnet to protect the HTS leads without quenching the MICE magnets. This report describes a method that one can use to protect the HTS leads in the event of a power failure at the Rutherford Appleton Laboratory (RAL).« less

Design of conduction cooling system for a high current HTS DC reactor

NASA Astrophysics Data System (ADS)

Dao, Van Quan; Kim, Taekue; Le Tat, Thang; Sung, Haejin; Choi, Jongho; Kim, Kwangmin; Hwang, Chul-Sang; Park, Minwon; Yu, In-Keun

2017-07-01

A DC reactor using a high temperature superconducting (HTS) magnet reduces the reactor’s size, weight, flux leakage, and electrical losses. An HTS magnet needs cryogenic cooling to achieve and maintain its superconducting state. There are two methods for doing this: one is pool boiling and the other is conduction cooling. The conduction cooling method is more effective than the pool boiling method in terms of smaller size and lighter weight. This paper discusses a design of conduction cooling system for a high current, high temperature superconducting DC reactor. Dimensions of the conduction cooling system parts including HTS magnets, bobbin structures, current leads, support bars, and thermal exchangers were calculated and drawn using a 3D CAD program. A finite element method model was built for determining the optimal design parameters and analyzing the thermo-mechanical characteristics. The operating current and inductance of the reactor magnet were 1,500 A, 400 mH, respectively. The thermal load of the HTS DC reactor was analyzed for determining the cooling capacity of the cryo-cooler. The study results can be effectively utilized for the design and fabrication of a commercial HTS DC reactor.

Localizing on-scalp MEG sensors using an array of magnetic dipole coils.

PubMed

Pfeiffer, Christoph; Andersen, Lau M; Lundqvist, Daniel; Hämäläinen, Matti; Schneiderman, Justin F; Oostenveld, Robert

2018-01-01

Accurate estimation of the neural activity underlying magnetoencephalography (MEG) signals requires co-registration i.e., determination of the position and orientation of the sensors with respect to the head. In modern MEG systems, an array of hundreds of low-Tc SQUID sensors is used to localize a set of small, magnetic dipole-like (head-position indicator, HPI) coils that are attached to the subject's head. With accurate prior knowledge of the positions and orientations of the sensors with respect to one another, the HPI coils can be localized with high precision, and thereby the positions of the sensors in relation to the head. With advances in magnetic field sensing technologies, e.g., high-Tc SQUIDs and optically pumped magnetometers (OPM), that require less extreme operating temperatures than low-Tc SQUID sensors, on-scalp MEG is on the horizon. To utilize the full potential of on-scalp MEG, flexible sensor arrays are preferable. Conventional co-registration is impractical for such systems as the relative positions and orientations of the sensors to each other are subject-specific and hence not known a priori. Herein, we present a method for co-registration of on-scalp MEG sensors. We propose to invert the conventional co-registration approach and localize the sensors relative to an array of HPI coils on the subject's head. We show that given accurate prior knowledge of the positions of the HPI coils with respect to one another, the sensors can be localized with high precision. We simulated our method with realistic parameters and layouts for sensor and coil arrays. Results indicate co-registration is possible with sub-millimeter accuracy, but the performance strongly depends upon a number of factors. Accurate calibration of the coils and precise determination of the positions and orientations of the coils with respect to one another are crucial. Finally, we propose methods to tackle practical challenges to further improve the method.

Localizing on-scalp MEG sensors using an array of magnetic dipole coils

PubMed Central

Andersen, Lau M.; Lundqvist, Daniel; Hämäläinen, Matti; Schneiderman, Justin F.; Oostenveld, Robert

2018-01-01

Accurate estimation of the neural activity underlying magnetoencephalography (MEG) signals requires co-registration i.e., determination of the position and orientation of the sensors with respect to the head. In modern MEG systems, an array of hundreds of low-Tc SQUID sensors is used to localize a set of small, magnetic dipole-like (head-position indicator, HPI) coils that are attached to the subject’s head. With accurate prior knowledge of the positions and orientations of the sensors with respect to one another, the HPI coils can be localized with high precision, and thereby the positions of the sensors in relation to the head. With advances in magnetic field sensing technologies, e.g., high-Tc SQUIDs and optically pumped magnetometers (OPM), that require less extreme operating temperatures than low-Tc SQUID sensors, on-scalp MEG is on the horizon. To utilize the full potential of on-scalp MEG, flexible sensor arrays are preferable. Conventional co-registration is impractical for such systems as the relative positions and orientations of the sensors to each other are subject-specific and hence not known a priori. Herein, we present a method for co-registration of on-scalp MEG sensors. We propose to invert the conventional co-registration approach and localize the sensors relative to an array of HPI coils on the subject’s head. We show that given accurate prior knowledge of the positions of the HPI coils with respect to one another, the sensors can be localized with high precision. We simulated our method with realistic parameters and layouts for sensor and coil arrays. Results indicate co-registration is possible with sub-millimeter accuracy, but the performance strongly depends upon a number of factors. Accurate calibration of the coils and precise determination of the positions and orientations of the coils with respect to one another are crucial. Finally, we propose methods to tackle practical challenges to further improve the method. PMID:29746486

Multiple sensory modalities used by squid in successful predator evasion throughout ontogeny.

PubMed

York, Carly A; Bartol, Ian K; Krueger, Paul S

2016-09-15

Squid rely on multiple sensory systems for predator detection. In this study we examine the role of two sensory systems, the lateral line analogue and vision, in successful predator evasion throughout ontogeny. Squid Doryteuthis pealeii and Lolliguncula brevis were recorded using high-speed videography in the presence of natural predators under light and dark conditions with their lateral line analogue intact or ablated via a pharmacological technique. Paralarval squid showed reduced escape responses when ablated; however, no differences were found between light and dark conditions in non-ablated paralarvae, as was previously shown in juveniles and adults, indicating that the lateral line analogue is integral for predator detection early in life. However, vision does play a role in survival because ablated squid in dark conditions had lower levels of survival than all other treatments. Throughout ontogeny, squid oriented themselves anteriorly towards the oncoming predator, maximizing sensory input to the lateral line analogue system and providing better positioning for tail-first escape jetting, the preferred escape mode. Ablated juveniles and adults had lower response times, escape velocities and peak acceleration than non-ablated individuals, indicating that the lateral line analogue enables squid to respond quicker and with more powerful jets to a predator and maximize escape success. Our findings reveal that the lateral line analogue plays a role in predator detection and successful escape response at the earliest life stages, and continues to contribute to successful evasion by aiding visual cues in juvenile and adult squid. © 2016. Published by The Company of Biologists Ltd.

Simulation and measurement of a Ka-band HTS MMIC Josephson junction mixer

NASA Astrophysics Data System (ADS)

Zhang, Ting; Pegrum, Colin; Du, Jia; Guo, Yingjie Jay

2017-01-01

We report modeling and simulation results for a Ka band high-temperature superconducting (HTS) monolithic microwave integrated circuit (MMIC) Josephson junction mixer. A Verilog-A model of a Josephson junction is established and imported into the system simulator to realize a full HTS MMIC circuit simulation containing the HTS passive circuit models. Impedance matching optimization between the junction and passive devices is investigated. Junction DC I-V characteristics, current and local oscillator bias conditions and mixing performance are simulated and compared with the experimental results. Good agreement is obtained between the simulation and measurement results.

NMR/MRI with hyperpolarized gas and high Tc SQUID

DOEpatents

Schlenga, Klaus; de Souza, Ricardo E.; Wong-Foy, Annjoe; Clarke, John; Pines, Alexander

2000-01-01

A method and apparatus for the detection of nuclear magnetic resonance (NMR) signals and production of magnetic resonance imaging (MRI) from samples combines the use of hyperpolarized inert gases to enhance the NMR signals from target nuclei in a sample and a high critical temperature (Tc) superconducting quantum interference device (SQUID) to detect the NMR signals. The system operates in static magnetic fields of 3 mT or less (down to 0.1 mT), and at temperatures from liquid nitrogen (77K) to room temperature. Sample size is limited only by the size of the magnetic field coils and not by the detector. The detector is a high Tc SQUID magnetometer designed so that the SQUID detector can be very close to the sample, which can be at room temperature.

Fabrication and characterization of hybrid Nb-YBCO dc SQUIDs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frack, E.K.; Drake, R.E.; Patt, R.

This paper reports on the fabrication of hybrid low T{sub c}/high T{sub c} dc SQUIDs of two flavors. The first kind utilizes niobium tunnel junctions and a YBCO film strip as the most inductive portion of the SQUID loop. This configuration allows a direct measurement of the inductance of the YBCO microstrip from which the effective penetration depth can be calculated. The successful fabrication of these SQUIDs has required 1. superconducting Nb-to-YBCO contacts, 2. deposition and patterning of an SiO{sub 2} insulation layer over YBCO, and 3. selective patterning of niobium and SiO{sub 2} relative to YBCO. All these processmore » steps are pertinent to the eventual use of YBCO thin films in electronic devices.« less

Ferromagnetic resonance response of electron-beam patterned arrays of ferromagnetic nanoparticles

NASA Astrophysics Data System (ADS)

Jung, Sukkoo; Watkins, Byron; Feller, Jeffrey; Ketterson, John; Chandrasekhar, Venkat

2001-03-01

We report on the fabrication and the dynamic magnetic properties of periodic permalloy dot arrays. Electron-beam lithography and e-gun evaporation have been used to make the arrays with the aspect ratio of 2 (dot diameter : 40 nm, height : 80 nm) and periods of 100 - 200 nm. The magnetic properties of the arrays and their interactions have been investigated by ferromagnetic resonance (FMR), magnetic force microscopy (MFM), and SQUID magnetometry. The measured FMR data show that the position and magnitude of resonant absorption peaks strongly depend on the angle between magnetic field and the lattice structure. The results of dot arrays with various kinds of structural parameters will be presented. Supported by Army Research Office, DAAD19-99-1-0334/P001

Intermodulation in nonlinear SQUID metamaterials: Experiment and theory

NASA Astrophysics Data System (ADS)

Zhang, Daimeng; Trepanier, Melissa; Antonsen, Thomas; Ott, Edward; Anlage, Steven M.

2016-11-01

The response of nonlinear metamaterials and superconducting electronics to two-tone excitation is critical for understanding their use as low-noise amplifiers and tunable filters. A new setting for such studies is that of metamaterials made of radio frequency superconducting quantum interference devices (rf-SQUIDs). The two-tone response of self-resonant rf-SQUID meta-atoms and metamaterials is studied here via intermodulation (IM) measurement over a broad range of tone frequencies and tone powers. A sharp onset followed by a surprising strongly suppressed IM region near the resonance is observed. Using a two time scale analysis technique, we present an analytical theory that successfully explains our experimental observations. The theory predicts that the IM can be manipulated with tone power, center frequency, frequency difference between the two tones, and temperature. This quantitative understanding potentially allows for the design of rf-SQUID metamaterials with either very low or very high IM response.

Application of SQUIDs for registration of biomagnetic signals

NASA Astrophysics Data System (ADS)

Voitovych, I. D.; Primin, M. A.; Sosnytskyy, V. N.

2012-04-01

Supersensitive magnetometric systems based on low-temperature SQUIDs have been designed to conduct research in cardiology (magnetocardiography) and to examine distribution of magnetic nanoparticles in biologic objects. Such SQUID magnetometric systems are distinguished by their noise immunity enabling research in nonscreened rooms. High repeatability of research outcomes has been confirmed. The use of magnetocardiographic systems has permitted a new screening information technology to be developed to diagnose heart diseases at early stages. Magnetic imaging of heart's action currents is an ideal way to test local electrical heterogeneity of myocardium. It is shown that magnetocardiography has a significant potential for both basic science of analysis of heart's biosignals and clinical cardiologic practice. A SQUID magnetometric system measuring magnetic signals radiated by the organs of laboratory animals is described. Information technology for automatic recording and transforming magnetometric data has been developed; the measurement of signals over rats' livers while injecting intravenously the nanoparticles of iron oxides and lead solutions are presented.

Practical SQUID Instrument for Nondestructive Testing

NASA Technical Reports Server (NTRS)

Tralshawala, N.; Claycomb, J. R.; Miller, John H., Jr.

1997-01-01

We report on the development of a scanning eddy-current imaging system designed to detect deep subsurface flaws in conducting materials. A high transition temperature (high-T c) superconducting quantum interference device (SQUID) magnetometer is employed to provide the required sensitivity at low frequencies, while a combination of small cylindrical high-Tc superconducting and A-metal shields enable the instrument to be scanned in a magnetically noisy environment, rather than the object under test. The shields are arranged to prevent unwanted excitation and ambient noise fields from reaching the SQUID, and to enhance spatial resolution and minimize undesirable edge effects. Thus far, the instrument has successfully detected cracks and pits through 10 layers of aluminum, with a combined thickness of 5 cm at room temperature.

Squid-derived chitin oligosaccharides are a chemotactic signal during colonization by Vibrio fischeri.

PubMed

Mandel, Mark J; Schaefer, Amy L; Brennan, Caitlin A; Heath-Heckman, Elizabeth A C; Deloney-Marino, Cindy R; McFall-Ngai, Margaret J; Ruby, Edward G

2012-07-01

Chitin, a polymer of N-acetylglucosamine (GlcNAc), is noted as the second most abundant biopolymer in nature. Chitin serves many functions for marine bacteria in the family Vibrionaceae ("vibrios"), in some instances providing a physical attachment site, inducing natural genetic competence, and serving as an attractant for chemotaxis. The marine luminous bacterium Vibrio fischeri is the specific symbiont in the light-emitting organ of the Hawaiian bobtail squid, Euprymna scolopes. The bacterium provides the squid with luminescence that the animal uses in an antipredatory defense, while the squid supports the symbiont's nutritional requirements. V. fischeri cells are harvested from seawater during each host generation, and V. fischeri is the only species that can complete this process in nature. Furthermore, chitin is located in squid hemocytes and plays a nutritional role in the symbiosis. We demonstrate here that chitin oligosaccharides produced by the squid host serve as a chemotactic signal for colonizing bacteria. V. fischeri uses the gradient of host chitin to enter the squid light organ duct and colonize the animal. We provide evidence that chitin serves a novel function in an animal-bacterial mutualism, as an animal-produced bacterium-attracting synomone.

Basic and Applied Magnetism with a Squid Gradiometer.

DTIC Science & Technology

1985-12-01

r , , WV w- =v- -V,; . r Zr! I , : r -. : r , : s : i . : I , C CI SQUID ta) 0 7 - .- 4 , 4 4 4 - .44* . . 2 Te 1 I T ...... 2zt 14 tbt’faceewient...incheS) iuSteed D~ISPLACE4ENT ’ . • •. . , I t ( pi A, , I phud.I’ t h bh r . /Os ,7/,/( ds I DR8 _ I Is i it r V( ttw( lt hd ,h r % I I VS94 SQUID...magnetization. Barkhausen Reversible Missing

Assessment of High Temperature Superconducting (HTS) electric motors for rotorcraft propulsion

NASA Technical Reports Server (NTRS)

Doernbach, Jay

1990-01-01

The successful development of high temperature superconductors (HTS) could have a major impact on future aeronautical propulsion and aeronautical flight vehicle systems. Applications of high temperature superconductors have been envisioned for several classes of aeronautical systems, including subsonic and supersonic transports, hypersonic aircraft, V/STOL aircraft, rotorcraft and solar powered aircraft. The potential of HTS electric motors and generators for providing primary shaft power for rotorcraft propulsion is examined. Three different sized production helicopters were investigated; namely, the Bell Jet Ranger, the Sikorsky Black Hawk and the Sikorsky Super Stallion. These rotorcraft have nominal horsepower ratings of 500, 3600, and 13400 respectively. Preliminary results indicated that an all-electric HTS drive system produces an improvement in rotorcraft Takeoff Gross Weight (TOGW) for those rotorcraft with power ratings above 2000 horsepower. The predicted TOGW improvements are up to 9 percent for the medium-sized Sikorsky Black Hawk and up to 20 percent for the large-sized Sikorsky Super Stallion. The small-sized Bell Jet Ranger, however, experienced a penalty in TOGW with the all-electric HTS drive system.

A YBCO RF-squid variable temperature susceptometer and its applications

NASA Technical Reports Server (NTRS)

Zhou, Luwei; Qiu, Jinwu; Zhang, Xianfeng; Tang, Zhimin; Cai, Yimin; Qian, Yongjia

1991-01-01

The Superconducting QUantum Interference Device (SQUID) susceptibility using a high-temperature radio-frequency (rf) SQUID and a normal metal pick-up coil is employed in testing weak magnetization of the sample. The magnetic moment resolution of the device is 1 x 10(exp -6) emu, and that of the susceptibility is 5 x 10(exp -6) emu/cu cm.

jSquid: a Java applet for graphical on-line network exploration.

PubMed

Klammer, Martin; Roopra, Sanjit; Sonnhammer, Erik L L

2008-06-15

jSquid is a graph visualization tool for exploring graphs from protein-protein interaction or functional coupling networks. The tool was designed for the FunCoup web site, but can be used for any similar network exploring purpose. The program offers various visualization and graph manipulation techniques to increase the utility for the user. jSquid is available for direct usage and download at http://jSquid.sbc.su.se including source code under the GPLv3 license, and input examples. It requires Java version 5 or higher to run properly. erik.sonnhammer@sbc.su.se Supplementary data are available at Bioinformatics online.

A Planar Two-Dimensional Superconducting Bolometer Array for the Green Bank Telescope

NASA Technical Reports Server (NTRS)

Benford, Dominic; Staguhn, Johannes G.; Chervenak, James A.; Chen, Tina C.; Moseley, S. Harvey; Wollack, Edward J.; Devlin, Mark J.; Dicker, Simon R.; Supanich, Mark

2004-01-01

In order to provide high sensitivity rapid imaging at 3.3mm (90GHz) for the Green Bank Telescope - the world's largest steerable aperture - a camera is being built by the University of Pennsylvania, NASA/GSFC, and NRAO. The heart of this camera is an 8x8 close-packed, Nyquist-sampled detector array. We have designed and are fabricating a functional superconducting bolometer array system using a monolithic planar architecture. Read out by SQUID multiplexers, the superconducting transition edge sensors will provide fast, linear, sensitive response for high performance imaging. This will provide the first ever superconducting bolometer array on a facility instrument.

Prototyping a new, high-temperature SQUID magnetometer system

NASA Astrophysics Data System (ADS)

Grappone, J. Michael; Shaw, John; Biggin, Andrew J.

2017-04-01

High-sensitivity Superconducting Quantum Inference Devices (SQUIDs) and μ-metal shielding have largely solved paleomagnetic noise problems. Combing the two allows successful measurements of previously unusable samples, generally sediments with very weak (<10 pAm2) magnetizations. The improved sensitivity increases the fidelity of magnetic field variation surveys, but surveys continue to be somewhat slow. SQUIDs have historically been expensive to buy and operate, but technological advances now allow them to operate at liquid nitrogen temperatures (77 K), drastically reducing their costs. Step-wise thermal paleomagnetics studies cause large lag times during later steps as a result of heating from and cooling to room temperature for measurements. If the cooling step is removed entirely, however, the lag time drops by at least half. Available magnetometers currently provide either SQUID-level (0.1 - 1 pAm2) sensitivity or continuous heating. Combining a SQUID magnetometer with a high temperature oven is the logical next step to uncover the mysteries of the paleofield. However, the few that currently offer high temperature capabilities with noise levels approaching 10 pAm2 require either spinning or vibrating the sample, necessitating additional handling and potentially causing damage to the sample. Two primary factors have plagued previous developments: noise levels and temperature gradients. Our entire system is shielded from the environment using 4 layers of μ-metal. Our sample oven (designed for 7 mm diameter samples) sits inside a copper pipe and operates at high-frequency AC voltages. High frequency (10 kHz) AC current reduces the skin depth of radio frequency (RF) electromagnetic noise, which allows the 2 mm-thick copper shielding to reduce RF noise by ˜94%, leaving a residual field of ˜1.5 nT at the SQUID's location, 14.9 mm from the oven. A computer-controlled Eurotherm 3216 thermal controller regulates the temperature within ± 0.5 ˚ C. To reach 700 ˚ C

Ordered arrays of Ni magnetic nanowires: Synthesis and investigation

NASA Astrophysics Data System (ADS)

Napolskii, K. S.; Eliseev, A. A.; Yesin, N. V.; Lukashin, A. V.; Tretyakov, Yu. D.; Grigorieva, N. A.; Grigoriev, S. V.; Eckerlebe, H.

2007-03-01

The present study is focused on the synthesis and investigation of anodic aluminum oxide (AAO) films and magnetic nanocomposites Ni/AAO obtained by Ni electrodeposition into porous matrix. AAO membranes and magnetic nanocomposites were investigated by HRSEM, EDX microanalysis, XRD, nitrogen capillary adsorption method, SQUID magnetometry, and polarized small-angle neutron scattering (SANS). The influence of synthesis conditions and form factor effect on the magnetic properties of nanowire arrays is reported.

AC losses in horizontally parallel HTS tapes for possible wireless power transfer applications

NASA Astrophysics Data System (ADS)

Shen, Boyang; Geng, Jianzhao; Zhang, Xiuchang; Fu, Lin; Li, Chao; Zhang, Heng; Dong, Qihuan; Ma, Jun; Gawith, James; Coombs, T. A.

2017-12-01

This paper presents the concept of using horizontally parallel HTS tapes with AC loss study, and the investigation on possible wireless power transfer (WPT) applications. An example of three parallel HTS tapes was proposed, whose AC loss study was carried out both from experiment using electrical method; and simulation using 2D H-formulation on the FEM platform of COMSOL Multiphysics. The electromagnetic induction around the three parallel tapes was monitored using COMSOL simulation. The electromagnetic induction and AC losses generated by a conventional three turn coil was simulated as well, and then compared to the case of three parallel tapes with the same AC transport current. The analysis demonstrates that HTS parallel tapes could be potentially used into wireless power transfer systems, which could have lower total AC losses than conventional HTS coils.

Extended focal-plane array development for the International X-ray Observatory

NASA Astrophysics Data System (ADS)

Smith, Stephen J.; Bandler, Simon R.; Beyer, Joern; Chervenak, James A.; Drung, Dietmar; Eckart, Megan E.; Finkbeiner, Fred M.; Kelley, Richard L.; Kilbourne, Caroline A.; Scott Porter, F.; Sadleir, John E.

2009-12-01

We are developing arrays of transition-edge sensors (TES's) for the International X-ray observatory (IXO). The IXO microcalorimeter array will consist of a central 40×40 core of 300 μm pitch pixels with a resolution of 2.5 eV from 0.3-10 keV. To maximize the science return from the mission, an outer extended array is also required. This 52×52 array (2304 elements surrounding the core) of 600 μm pitch pixels increases the field-of-view from 2' to 5.4' with a resolution of 10 eV. However, significantly increasing the number of readout channels is unfavorable due to the increase in mass and power of the readout chain as well as adding complexity at the focal plane. Consequently, we are developing position-sensitive devices which maintain the same plate scale but at a reduced number of readout channels. One option is to use multiple absorber elements with different thermal conductances to a single TES. Position discrimination is achieved from differences in the pulse rise-time. Another new option is to inductively couple several TES's to a single SQUID. Position discrimination can be achieved by using different combinations of coupling polarity, inductive couplings and heat sink conductances. We present first results demonstrating <9 eV across four 500 μm pixels coupled to a single SQUID. A further possibility is to increase the number of channels to be time-division multiplexed in a single column at some expense in resolution. In this paper we discuss experimental results and trade-offs for these extended array options.

Measurements and tests of HTS bulk material in resistive fault current limiters

NASA Astrophysics Data System (ADS)

Noe, M.; Juengst, K.-P.; Werfel, F. N.; Elschner, S.; Bock, J.; Wolf, A.; Breuer, F.

2002-08-01

The application of superconducting fault current limiters (SCFCL) depends highly on their technical and economical benefits. Therefore it is obvious that the main requirements on the SCFCL are a reliable, fail-safe and rapid current limitation, low losses, and an inexpensive production. As a potential candidate material we have investigated HTS bulk material in resistive fault current limiters. Our report focuses on the E- j-curves, the AC-losses and the quench behaviour of melt cast processed-BSCCO 2212 and melt textured polycrystalline-YBCO 123. Within a temperature range from 64 to 80 K E- j-curves and AC losses of HTS elements were measured. The measurement results show that HTS bulk material meets the SCFCL specifications. In order to avoid hot spots during limitation and to improve mechanical stability a metallic bypass is needed. First test results of the quench behaviour of HTS bulk material with metallic bypass demonstrate safe limitation up to the specified electrical field of 100 V/m.

Transient analysis of an HTS DC power cable with an HVDC system

NASA Astrophysics Data System (ADS)

Dinh, Minh-Chau; Ju, Chang-Hyeon; Kim, Jin-Geun; Park, Minwon; Yu, In-Keun; Yang, Byeongmo

2013-11-01

The operational characteristics of a superconducting DC power cable connected to a highvoltage direct current (HVDC) system are mainly concerned with the HVDC control and protection system. To confirm how the cable operates with the HVDC system, verifications using simulation tools are needed. This paper presents a transient analysis of a high temperature superconducting (HTS) DC power cable in connection with an HVDC system. The study was conducted via the simulation of the HVDC system and a developed model of the HTS DC power cable using a real time digital simulator (RTDS). The simulation was performed with some cases of short circuits that may have caused system damage. The simulation results show that during the faults, the quench did not happen with the HTS DC power cable because the HVDC controller reduced some degree of the fault current. These results could provide useful data for the protection design of a practical HVDC and HTS DC power cable system.

Superconducting Quantum Interference Device Array Based High Frequency Direction Finding on an Airborne Platform

DTIC Science & Technology

is performed using the MUSIC algorithm on the signals received on the non-uniform phased array, and the ESPRIT algorithm is used on the signals...received on the non-colocated vector sensor. The simulation results show that the MUSIC algorithm using 2D Bi-SQUIDs is able to differentiate two signals

Complex Visual Adaptations in Squid for Specific Tasks in Different Environments

PubMed Central

Chung, Wen-Sung; Marshall, N. Justin

2017-01-01

In common with their major competitors, the fish, squid are fast moving visual predators that live over a great range of depths in the ocean. Both squid and fish show a variety of adaptations with respect to optical properties, receptors and their underlying neural circuits, and these adaptations are often linked to the light conditions of their specific niche. In contrast to the extensive investigations of adaptive strategies in fish, vision in response to the varying quantity and quality of available light, our knowledge of visual adaptations in squid remains sparse. This study therefore undertook a comparative study of visual adaptations and capabilities in a number of squid species collected between 0 and 1,200 m. Histology, magnetic resonance imagery (MRI), and depth distributions were used to compare brains, eyes, and visual capabilities, revealing that the squid eye designs reflect the lifestyle and the versatility of neural architecture in its visual system. Tubular eyes and two types of regional retinal deformation were identified and these eye modifications are strongly associated with specific directional visual tasks. In addition, a combination of conventional and immuno-histology demonstrated a new form of a complex retina possessing two inner segment layers in two mid-water squid species which they rhythmically move across a broad range of depths (50–1,000 m). In contrast to their relatives with the regular single-layered inner segment retina live in the upper mesopelagic layer (50–400 m), the new form of retinal interneuronal layers suggests that the visual sensitivity of these two long distance vertical migrants may increase in response to dimmer environments. PMID:28286484

Assessing the trophic position and ecological role of squids in marine ecosystems by means of food-web models

NASA Astrophysics Data System (ADS)

Coll, Marta; Navarro, Joan; Olson, Robert J.; Christensen, Villy

2013-10-01

We synthesized available information from ecological models at local and regional scales to obtain a global picture of the trophic position and ecological role of squids in marine ecosystems. First, static food-web models were used to analyze basic ecological parameters and indicators of squids: biomass, production, consumption, trophic level, omnivory index, predation mortality diet, and the ecological role. In addition, we developed various dynamic temporal simulations using two food-web models that included squids in their parameterization, and we investigated potential impacts of fishing pressure and environmental conditions for squid populations and, consequently, for marine food webs. Our results showed that squids occupy a large range of trophic levels in marine food webs and show a large trophic width, reflecting the versatility in their feeding behaviors and dietary habits. Models illustrated that squids are abundant organisms in marine ecosystems, and have high growth and consumption rates, but these parameters are highly variable because squids are adapted to a large variety of environmental conditions. Results also show that squids can have a large trophic impact on other elements of the food web, and top-down control from squids to their prey can be high. In addition, some squid species are important prey of apical predators and may be keystone species in marine food webs. In fact, we found strong interrelationships between neritic squids and the populations of their prey and predators in coastal and shelf areas, while the role of squids in open ocean and upwelling ecosystems appeared more constrained to a bottom-up impact on their predators. Therefore, large removals of squids will likely have large-scale effects on marine ecosystems. In addition, simulations confirm that squids are able to benefit from a general increase in fishing pressure, mainly due to predation release, and quickly respond to changes triggered by the environment. Squids may thus

Second order gradiometer and dc SQUID integrated on a planar substrate

NASA Astrophysics Data System (ADS)

van Nieuwenhuyzen, G. J.; de Waal, V. J.

1985-02-01

An integrated system of a thin-film niobium dc superconducting quantum interference device (SQUID) and a second order gradiometer on a planar substrate is described. The system consists of a dc SQUID with eight loops in parallel, each sensitive to the second derivative ∂2Bz/∂x2 of the magnetic field. The calculated SQUID inductance is 1.3 nH. With an overall size of 16×16.5 mm2 a sensitivity of 1.5×10-9 Tm-2 Hz-1/2 is obtained. The measured transfer function for uniform fields perpendicular to the plane of the gradiometer is 2.1×10-7 T Φ-10.

HTS cryogenic current comparator for non-invasive sensing of charged-particle beams

NASA Astrophysics Data System (ADS)

Hao, L.; Gallop, J. C.; Macfarlane, J. C.; Carr, C.

2002-03-01

The principle of the superconducting cryogenic direct-current comparator (CCC) is applied to the non-invasive sensing of charged-particle beams (ions, electrons). With the use of HTS components it is feasible to envisage applications, for example, in precision mass spectrometry, in real-time monitoring of ion-beam implantation currents and for the determination of the Faraday fundamental constant. We have developed a novel current concentrating technique using HTS thick-film material, to increase the sensitivity of the CCC. Recent simulations and experimental measurements of the flux and current concentration ratios, frequency response and linearity of a prototype HTS-CCC operating at 77 K are described.

Compact integrated dc SQUID gradiometer

NASA Astrophysics Data System (ADS)

de Waal, V. J.; Klapwijk, T. M.

1982-10-01

An all-niobium integrated system of first-order gradiometer and dc suprconducting quantum interference device (SQUID) has been developed. It is relatively simple to fabricate, has an overall size of 17×12 mm and a sensitivity of 3.5×10-12 T m-1 Hz-1/2.

The effect of temperature on pinning mechanisms in HTS composites

NASA Astrophysics Data System (ADS)

Sotnikova, A. P.; Rudnev, I. A.

2016-09-01

Pinning mechanism in samples of second generation tapes (2G) of high-temperature superconductors (HTS) was studied The critical current and the pinning force were calculated from the magnetization curves measured in the temperature range of 4.2 - 77 K in magnetic fields up to 14 Tesla using vibration sample magnetometer. To determine the pinning mechanism the dependences of pinning force on magnetic field were constructed according to the Dew-Hughes model and Kramer's rule. The obtained dependences revealed a significant influence of the temperature on effectiveness of different types of pinning. At low temperatures the 2G HTS tapes of different manufacturers demonstrated an equal efficiency of the pinning centers but with temperature increase the differences in pinning mechanisms as well as in properties and effectiveness of the pinning centers become obvious. The influence of the pinning mechanism on the energy losses in HTS tapes was shown.

Effects of thermal processing and various chemical substances on formaldehyde and dimethylamine formation in squid Dosidicus gigas.

PubMed

Zhu, Junli; Li, Jianrong; Jia, Jia

2012-09-01

Trimethylamine oxide (TMAO) in squid is demethylated to dimethylamine (DMA) and formaldehyde (FA) during storage and processing. This study examined the effects of thermal processing and various chemical substances on FA and DMA formation in squid. The thermal conversion of TMAO was assessed by analysing four squid and four gadoid fish species, which revealed that FA, DMA and trimethylamine (TMA) were gradually produced in squid, whereas TMA increased and FA decreased in gadoid fish. A significant increase in both FA and DMA levels was observed in the supernatant of jumbo squid with increased heating temperature and extended heating time at pH 6-7. Ferrous chloride combined with cysteine and/or ascorbate had a significantly positive effect on FA formation in the heated supernatant of jumbo squid. No significant difference was observed in the levels of Cu and Fe in squid and gadoid fish. The capability of Fe(2+) to promote the formation of FA and DMA was not completely attributable to its reducing power in squid. Non-enzymatic decomposition of TMAO was a key pathway during the thermal processing of jumbo squid, and Fe(2+) was a crucial activator in the formation of FA and DMA. Copyright © 2012 Society of Chemical Industry.

Lowering effect of firefly squid powder on triacylglycerol content and glucose-6-phosphate dehydrogenase activity in rat liver.

PubMed

Takeuchi, Hiroyuki; Morita, Ritsuko; Shirai, Yoko; Nakagawa, Yoshihisa; Terashima, Teruya; Ushikubo, Shun; Matsuo, Tatsuhiro

2014-01-01

Effects of dietary firefly squid on serum and liver lipid levels were investigated. Male Wistar rats were fed a diet containing 5% freeze-dried firefly squid or Japanese flying squid for 2 weeks. There was no significant difference in the liver triacylglycerol level between the control and Japanese flying squid groups, but the rats fed the firefly squid diet had a significantly lower liver triacylglycerol content than those fed the control diet. No significant difference was observed in serum triacylglycerol levels between the control and firefly squid groups. The rats fed the firefly squid had a significantly lower activity of liver glucose-6-phosphate dehydrogenase compared to the rats fed the control diet. There was no significant difference in liver fatty acid synthetase activity among the three groups. Hepatic gene expression and lipogenic enzyme activity were investigated; a DNA microarray showed that the significantly enriched gene ontology category of down-regulated genes in the firefly squid group was "lipid metabolic process". The firefly squid group had lower mRNA level of glucose-6-phosphate dehydrogenase compared to the controls. These results suggest that an intake of firefly squid decreases hepatic triacylglycerol in rats, and the reduction of mRNA level and enzyme activity of glucose-6-phosphate dehydrogenase might be related to the mechanisms.

Identifying Pelagic Habitat Hotspots of Neon Flying Squid in the Temperate Waters of the Central North Pacific.

PubMed

Alabia, Irene D; Saitoh, Sei-Ichi; Mugo, Robinson; Igarashi, Hiromichi; Ishikawa, Yoichi; Usui, Norihisa; Kamachi, Masafumi; Awaji, Toshiyuki; Seito, Masaki

2015-01-01

We identified the pelagic habitat hotspots of the neon flying squid (Ommastrephes bartramii) in the central North Pacific from May to July and characterized the spatial patterns of squid aggregations in relation to oceanographic features such as mesoscale oceanic eddies and the Transition Zone Chlorophyll-a Front (TZCF). The data used for the habitat model construction and analyses were squid fishery information, remotely-sensed and numerical model-derived environmental data from May to July 1999-2010. Squid habitat hotspots were deduced from the monthly Maximum Entropy (MaxEnt) models and were identified as regions of persistent high suitable habitat across the 12-year period. The distribution of predicted squid habitat hotspots in central North Pacific revealed interesting spatial and temporal patterns likely linked with the presence and dynamics of oceanographic features in squid's putative foraging grounds from late spring to summer. From May to June, the inferred patches of squid habitat hotspots developed within the Kuroshio-Oyashio transition zone (KOTZ; 37-40°N) and further expanded north towards the subarctic frontal zone (SAFZ; 40-44°N) in July. The squid habitat hotspots within the KOTZ and areas west of the dateline (160°W-180°) were likely influenced and associated with the highly dynamic and transient oceanic eddies and could possibly account for lower squid suitable habitat persistence obtained from these regions. However, predicted squid habitat hotspots located in regions east of the dateline (180°-160°W) from June to July, showed predominantly higher squid habitat persistence presumably due to their proximity to the mean position of the seasonally-shifting TZCF and consequent utilization of the highly productive waters of the SAFZ.

Development of RF Sensor Based on Two-cell SQUID

DTIC Science & Technology

2012-07-01

according to (8) is proportional to the reduced drive detuning, ωp0 is the resonant frequency for small oscillations, i.e. the plasma frequency of the...0/2 Φ= cnc IRπω (16) where Rn is the normal resistance of the Josephson junction in the SQUID, and L the inductance of the...17.7 μA, normal resistance 110.9 Ω, plasma frequency ωp 124 GHz and characteristic frequency 948 GHz. While the loop inductance of SQUID was 60 pH

Squid detected NMR and MRI at ultralow fields

DOEpatents

Clarke, John [Berkeley, CA; McDermott, Robert [Louisville, CO; Pines, Alexander [Berkeley, CA; Trabesinger, Andreas Heinz [CH-8006 Zurich, CH

2007-05-15

Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

Squid detected NMR and MRI at ultralow fields

DOEpatents

Clarke, John; McDermott, Robert; Pines, Alexander; Trabesinger, Andreas Heinz

2006-05-30

Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

Squid detected NMR and MRI at ultralow fields

DOEpatents

Clarke, John [Berkeley, CA; Pines, Alexander [Berkeley, CA; McDermott, Robert F [Monona, WI; Trabesinger, Andreas H [London, GB

2008-12-16

Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

SQUID detected NMR and MRI at ultralow fields

DOEpatents

Clarke, John; McDermott, Robert; Pines, Alexander; Trabesinger, Andreas Heinz

2006-10-03

Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

Transport characteristics of μ-SQUIDs for probing magnetism

NASA Astrophysics Data System (ADS)

Biswas, Sourav; Paul, Sagar; Parashari, Harsh; Winkelmann, Clemens B.; Courtois, Hervé; Gupta, Anjan K.

2018-04-01

We study the transport properties of niobium (Nb) based micron sized superconducting quantum interference devices (μ-SQUID), which are designed to eliminate thermal hysteresis down to 1.3 K. Current-voltage characteristics are non-hysterestic at the lowest temperature. Large voltage oscillations with magnetic field are observed for a wide range of bias currents with good flux sensitivity and reduced flux noise. However, devices with fins and devices on sapphire substrate show hysteresis for wide range of bath temperature. We have also been able to see the sign of magnetic response from a single micron size ferromagnetic permalloy ellipse using the μ-SQUID.

US Navy superconductivity program

NASA Technical Reports Server (NTRS)

Gubser, Donald U.

1991-01-01

Both the new high temperature superconductors (HTS) and the low temperature superconductors (LTS) are important components of the Navy's total plan to integrate superconductivity into field operational systems. Fundamental research is an important component of the total Navy program and focuses on the HTS materials. Power applications (ship propulsion) use LTS materials while space applications (millimeter wave electronics) use HTS materials. The Space Experiment to be conducted at NRL will involve space flight testing of HTS devices built by industry and will demonstrate the ability to engineer and space qualify these devices for systems use. Another important component of the Navy's effort is the development of Superconducting Quantum Interference Device (SQUID) magnetometers. This program will use LTS materials initially, but plans to implement HTS materials as soon as possible. Hybrid HTS/LTS systems are probable in many applications. A review of the status of the Navy's HTS materials research is given as well as an update on the Navy's development efforts in superconductivity.

Biomagnetism using SQUIDs: status and perspectives

NASA Astrophysics Data System (ADS)

Sternickel, Karsten; Braginski, Alex I.

2006-03-01

Biomagnetism involves the measurement and analysis of very weak local magnetic fields of living organisms and various organs in humans. Such fields can be of physiological origin or due to magnetic impurities or markers. This paper reviews existing and prospective applications of biomagnetism in clinical research and medical diagnostics. Currently, such applications require sensitive magnetic SQUID sensors and amplifiers. The practicality of biomagnetic methods depends especially on techniques for suppressing the dominant environmental electromagnetic noise, and on suitable nearly real-time data processing and interpretation methods. Of the many biomagnetic methods and applications, only the functional studies of the human brain (magnetoencephalography) and liver susceptometry are in clinical use, while functional diagnostics of the human heart (magnetocardiography) approaches the threshold of clinical acceptance. Particularly promising for the future is the ongoing research into low-field magnetic resonance anatomical imaging using SQUIDs.

Structural elements of the signal propagation pathway in squid rhodopsin and bovine rhodopsin.

PubMed

Sugihara, Minoru; Fujibuchi, Wataru; Suwa, Makiko

2011-05-19

Squid and bovine rhodopsins are G-protein coupled receptors (GPCRs) that activate Gq- and Gt-type G-proteins, respectively. To understand the structural elements of the signal propagation pathway, we performed molecular dynamics (MD) simulations of squid and bovine rhodopsins plus a detailed sequence analysis of class A GPCRs. The computations indicate that although the geometry of the retinal is similar in bovine and squid rhodopsins, the important interhelical hydrogen bond networks are different. In squid rhodopsin, an extended hydrogen bond network that spans ∼13 Å to Tyr315 on the cytoplasmic site is present regardless of the protonation state of Asp80. In contrast, the extended hydrogen bond network is interrupted at Tyr306 in bovine rhodopsin. Those differences in the hydrogen bond network may play significant functional roles in the signal propagation from the retinal binding site to the cytoplasmic site, including transmembrane helix (TM) 6 to which the G-protein binds. The MD calculations demonstrate that the elongated conformation of TM6 in squid rhodopsin is stabilized by salt bridges formed with helix (H) 9. Together with the interhelical hydrogen bonds, the salt bridges between TM6 and H9 stabilize the protein conformation of squid rhodopsin and may hinder the occurrence of large conformational changes that are observed upon activation of bovine rhodopsin. © 2011 American Chemical Society

Optimization study on the magnetic field of superconducting Halbach Array magnet

NASA Astrophysics Data System (ADS)

Shen, Boyang; Geng, Jianzhao; Li, Chao; Zhang, Xiuchang; Fu, Lin; Zhang, Heng; Ma, Jun; Coombs, T. A.

2017-07-01

This paper presents the optimization on the strength and homogeneity of magnetic field from superconducting Halbach Array magnet. Conventional Halbach Array uses a special arrangement of permanent magnets which can generate homogeneous magnetic field. Superconducting Halbach Array utilizes High Temperature Superconductor (HTS) to construct an electromagnet to work below its critical temperature, which performs equivalently to the permanent magnet based Halbach Array. The simulations of superconducting Halbach Array were carried out using H-formulation based on B-dependent critical current density and bulk approximation, with the FEM platform COMSOL Multiphysics. The optimization focused on the coils' location, as well as the geometry and numbers of coils on the premise of maintaining the total amount of superconductor. Results show Halbach Array configuration based superconducting magnet is able to generate the magnetic field with intensity over 1 Tesla and improved homogeneity using proper optimization methods. Mathematical relation of these optimization parameters with the intensity and homogeneity of magnetic field was developed.

Thermal Insulation Performance of Flexible Piping for Use in HTS Power Cables

NASA Technical Reports Server (NTRS)

Fesmire, James E.; Augustynowicz, S. D.; Demko, J. A.; Thompson, Karen (Technical Monitor)

2001-01-01

High-temperature superconducting (HTS) cables that typically operate at temperatures below 80 K are being developed for power transmission. The practical application of HTS power cables will require the use of flexible piping to contain the cable and the liquid nitrogen coolant. A study of thermal performance of multilayer insulation (MLI) was conducted in geometries representing both rigid and flexible piping. This experimental study performed at the Cryogenics Test Laboratory of NASA Kennedy Space Center provides a framework for the development of cost-effective, efficient thermal insulation systems that will support these long-distance flexible lines containing HTS power cables. The overall thermal performance of the insulation system for a rigid configuration and for a flexible configuration, simulating a flexible HTS power cable, was determined by the steady-state liquid nitrogen boiloff method under the full range of vacuum levels. Two different cylindrically rolled material systems were tested: a standard MLI and a layered composite insulation (LCI). Comparisons of ideal MLI, MLI on rigid piping, and MLI between flexible piping are presented.

Low resistance splices for HTS devices and applications

NASA Astrophysics Data System (ADS)

Lalitha, S. L.

2017-09-01

This paper discusses the preparation methodology and performance evaluation of low resistance splices made of the second generation (2G) high-temperature superconductor (HTS). These splices are required in a broad spectrum of HTS devices including a large aperture, high-field solenoid built in the laboratory to demonstrate a superconducting magnetic energy storage (SMES) device. Several pancake coils are assembled in the form of a nested solenoid, and each coil requires a hundred meters or more of 2G (RE)BCO tape. However, commercial availability of this superconductor with a very uniform physical properties is currently limited to shorter piece lengths. This necessitates us having splices to inter-connect the tape pieces within a pancake coil, between adjacent pancake coils, and to attach HTS current leads to the magnet assembly. As a part of the optimization and qualification of splicing process, a systematic study was undertaken to analyze the electrical performance of splices in two different configurations suitable for this magnet assembly: lap joint and spiral joint. The electrical performance is quantified in terms of the resistance of splices estimated from the current-voltage characteristics. It has been demonstrated that a careful application of this splicing technique can generate lap joints with resistance less than 1 nΩ at 77 K.

Development of REBCO HTS Magnet of Magnetic Bearing for Large Capacity Flywheel Energy Storage System

NASA Astrophysics Data System (ADS)

Mukoyama, Shinichi; Matsuoka, Taro; Furukawa, Makoto; Nakao, Kengo; Nagashima, Ken; Ogata, Masafumi; Yamashita, Tomohisa; Hasegawa, Hitoshi; Yoshizawa, Kazuhiro; Arai, Yuuki; Miyazaki, Kazuki; Horiuchi, Shinichi; Maeda, Tadakazu; Shimizu, Hideki

A flywheel energy storage system (FESS) is a promising electrical storage system that moderates fluctuation of electrical power from renewable energy sources. The FESS can charge and discharge the surplus electrical power repetitively with the rotating energy. Particularly, the FESS that utilizes a high temperature superconducting magnetic bearing (HTS bearing) is lower loss than conventional FESS that has mechanical bearing, and has property of longer life operation than secondary batteries. The HTS bearing consists of a HTS bulk and double-pancake coils used 2nd generation REBCO wires. In the development, the HTS double-pancake coils were fabricated and were provided for a levitation test to verify the possibility of the HTS bearing. We successfully confirmed the magnetic field was achieved to design value, and levitation force in the configuration of one YBCO bulk and five double pan-cake coils was obtained to a satisfactory force of 39.2 kN (4 tons).

Abbott Physicochemical Tiering (APT)--a unified approach to HTS triage.

PubMed

Cox, Philip B; Gregg, Robert J; Vasudevan, Anil

2012-07-15

The selection of the highest quality chemical matter from high throughput screening (HTS) is the ultimate aim of any triage process. Typically there are many hundreds or thousands of hits capable of modulating a given biological target in HTS with a wide range of physicochemical properties that should be taken into consideration during triage. Given the multitude of physicochemical properties that define drug-like space, a system needs to be in place that allows for a rapid selection of chemical matter based on a prioritized range of these properties. With this goal in mind, we have developed a tool, coined Abbott Physicochemical Tiering (APT) that enables hit prioritization based on ranges of these important physicochemical properties. This tool is now used routinely at Abbott to help prioritize hits out of HTS during the triage process. Herein we describe how this tool was developed and validated using Abbott internal high throughput ADME data (HT-ADME). Copyright © 2012 Elsevier Ltd. All rights reserved.

Development of RF Sensor Based on Two-Cell Squid

DTIC Science & Technology

2011-07-15

to (8) is proportional to the reduced drive detuning, ωp0 is the resonant frequency for small oscillations, i.e. the plasma frequency of the combined...2 Φ= cnc IRπω (16) where Rn is the normal resistance of the Josephson junction in the SQUID, and L the inductance of the...were about 9 fF. The critical current I0 of each junction in the SQUID was 17.7 μA, normal resistance 110.9 Ω, plasma frequency ωp 124 GHz and

Thermoelectric SQUID method for the detection of segregations

NASA Astrophysics Data System (ADS)

Hinken, Johann H.; Tavrin, Yury

2000-05-01

Aero engine turbine discs are most critical parts. Material inhomogeneities can cause disc fractures during the flight with fatal air disasters. Nondestructive testing (NDT) of the discs in various machining steps is necessary and performed as well as possible. Conventional NDT methods, however, like eddy current testing and ultrasonic testing have unacceptable limits. For example, subsurface segregations often cannot be detected directly but only indirectly in such cases when cracks already have developed from them. This may be too late. A new NDT method, which we call the Thermoelectric SQUID Method, has been developed. It allows for the detection of metallic inclusions within non-ferromagnetic metallic base material. This paper describes the results of a feasibility study on aero engine turbine discs made from Inconel® 718. These contained segregations that had been detected before by anodic etching. With the Thermoelectric SQUID Method, these segregations were detected again, and further segregations below the surfaces have been found, which had not been detected before. For this new NDT method the disc material is quasi-transparent. The Thermoelectric SQUID Method is also useful to detect distributed and localized inhomogeneities in pure metals like niobium sheets for particle accelerators.

SQUID sensor application for small metallic particle detection

NASA Astrophysics Data System (ADS)

Tanaka, Saburo; Hatsukade, Yoshimi; Ohtani, Takeyoshi; Suzuki, Shuichi

2009-04-01

High-Tc superconducting quantum interference device (SQUID) is an ultra-sensitive magnetic sensor. Since the performance of the SQUID is improved and stabilized, now it is ready for application. One strong candidate for application is a detection system of magnetic foreign matters in industrial products or beverages. There is a possibility that ultra-small metallic foreign matter has been accidentally mixed with industrial products such as lithium ion batteries. If this happens, the manufacturer of the product suffers a great loss recalling products. The outer dimension of metallic particles less than 100 μm cannot be detected by an X-ray imaging, which is commonly used for the inspection. Ionization of the material is also a big issue for beverages in the case of the X-ray imaging. Therefore a highly sensitive and safety detection system for small foreign matters is required. We developed detection systems based on high-Tc SQUID with a high-performance magnetic shield. We could successfully measure small iron particles of 100 μm on a belt conveyer and stainless steel balls of 300 μm in water. These detection levels were hard to be achieved by a conventional X-ray detection or other methods.

web cellHTS2: a web-application for the analysis of high-throughput screening data.

PubMed

Pelz, Oliver; Gilsdorf, Moritz; Boutros, Michael

2010-04-12

The analysis of high-throughput screening data sets is an expanding field in bioinformatics. High-throughput screens by RNAi generate large primary data sets which need to be analyzed and annotated to identify relevant phenotypic hits. Large-scale RNAi screens are frequently used to identify novel factors that influence a broad range of cellular processes, including signaling pathway activity, cell proliferation, and host cell infection. Here, we present a web-based application utility for the end-to-end analysis of large cell-based screening experiments by cellHTS2. The software guides the user through the configuration steps that are required for the analysis of single or multi-channel experiments. The web-application provides options for various standardization and normalization methods, annotation of data sets and a comprehensive HTML report of the screening data analysis, including a ranked hit list. Sessions can be saved and restored for later re-analysis. The web frontend for the cellHTS2 R/Bioconductor package interacts with it through an R-server implementation that enables highly parallel analysis of screening data sets. web cellHTS2 further provides a file import and configuration module for common file formats. The implemented web-application facilitates the analysis of high-throughput data sets and provides a user-friendly interface. web cellHTS2 is accessible online at http://web-cellHTS2.dkfz.de. A standalone version as a virtual appliance and source code for platforms supporting Java 1.5.0 can be downloaded from the web cellHTS2 page. web cellHTS2 is freely distributed under GPL.

AC HTS Transmission Cable for Integration into the Future EHV Grid of the Netherlands

NASA Astrophysics Data System (ADS)

Zuijderduin, R.; Chevtchenko, O.; Smit, J. J.; Aanhaanen, G.; Melnik, I.; Geschiere, A.

Due to increasing power demand, the electricity grid of the Netherlands is changing. The future grid must be capable to transmit all the connected power. Power generation will be more decentralized like for instance wind parks connected to the grid. Furthermore, future large scale production units are expected to be installed near coastal regions. This creates some potential grid issues, such as: large power amounts to be transmitted to consumers from west to east and grid stability. High temperature superconductors (HTS) can help solving these grid problems. Advantages to integrate HTS components at Extra High Voltage (EHV) and High Voltage (HV) levels are numerous: more power with less losses and less emissions, intrinsic fault current limiting capability, better control of power flow, reduced footprint, etc. Today's main obstacle is the relatively high price of HTS. Nevertheless, as the price goes down, initial market penetration for several HTS components is expected by year 2015 (e.g.: cables, fault current limiters). In this paper we present a design of intrinsically compensated EHV HTS cable for future grid integration. Discussed are the parameters of such cable providing an optimal power transmission in the future network.

HTS flux concentrator for non-invasive sensing of charged particle beams

NASA Astrophysics Data System (ADS)

Hao, L.; Gallop, J. C.; Macfarlane, J. C.; Carr, C.; Donaldson, G. B.

2001-12-01

The principle of the superconducting cryogenic current comparator (CCC) is applied to the non-invasive sensing of charged-particle beams (ions, electrons). With the use of HTS components it is feasible to envisage applications, for example, in precision mass spectrometry and real-time monitoring of ion-beam implantation currents. Recent simulations and experimental measurements of the flux concentration ratio, frequency response and linearity of a prototype HTS-CCC operating at 77 K are described.

SQUID-based microwave cavity search for dark-matter axions.

PubMed

Asztalos, S J; Carosi, G; Hagmann, C; Kinion, D; van Bibber, K; Hotz, M; Rosenberg, L J; Rybka, G; Hoskins, J; Hwang, J; Sikivie, P; Tanner, D B; Bradley, R; Clarke, J

2010-01-29

Axions in the microeV mass range are a plausible cold dark-matter candidate and may be detected by their conversion into microwave photons in a resonant cavity immersed in a static magnetic field. We report the first result from such an axion search using a superconducting first-stage amplifier (SQUID) replacing a conventional GaAs field-effect transistor amplifier. This experiment excludes KSVZ dark-matter axions with masses between 3.3 microeV and 3.53 microeV and sets the stage for a definitive axion search utilizing near quantum-limited SQUID amplifiers.

In situ DMSO hydration measurements of HTS compound libraries.

PubMed

Ellson, R; Stearns, R; Mutz, M; Brown, C; Browning, B; Harris, D; Qureshi, S; Shieh, J; Wold, D

2005-09-01

Compounds used in high throughput screening (HTS) are typically dissolved in DMSO. These solutions are stored automation-friendly racks of wells or tubes. DMSO is hygroscopic and quickly absorbs water from the atmosphere. When present in DMSO compound solutions, water can accelerate degradation and precipitation. Understanding DMSO hydration in an HTS compound library can improve storage and screening methods by managing the impact of water on compound stability. A non-destructive, acoustic method compatible with HTS has been developed to measure water content in DMSO solutions. Performance of this acoustic method was compared with an optical technique and found to be in good agreement. The accuracy and precision of acoustic measurements was shown to be under 3% over the tested range of DMSO solutions (0% to 35% water by volume) and insensitive to the presence of HTS compounds at typical storage concentrations. Time course studies of hydration for wells in 384-well and 1536-well microplates were performed. Well geometry, fluid volume, well position and atmospheric conditions were all factors in hydration rate. High rates of hydration were seen in lower-volume fills, higher-density multi-well plates and when there was a large differential between the humidity of the lab and the water content of the DMSO. For example, a 1536-well microplate filled with 2microL of 100% DMSO exposed for one hour to a laboratory environment with approximately 40% relative humidity will absorb over 6% water by volume. Understanding DMSO hydration rates as well as the ability to reverse library hydration are important steps towards managing stability and availability of compound libraries.

Simulation of chain of quenches on toroidal HTS-SMES taking account of thermal and electromagnetic characteristics

NASA Astrophysics Data System (ADS)

Oga, Y.; Noguchi, S.; Igarashi, H.

When a temperature rise occurs at a local area inside a coil of toroidal HTS-SMES by any reason, a temperature hotspot which results in a thermal runaway appears at the local area. Subsequently, after appearing the local normal zone in the HTS coil, the transport current of the HTS coil decrease since the resistance of HTS coil appears and the current partially flows into a parallel-connecting shunt resistance. However, if the transport current of the normal-transitioned HTS coil is hardly changed, the temperature on the hotspot would rise more and then the normal zone would spread rapidly. It may cause a serious accident due to high stored energy. Therefore, using the numerical simulation, we have investigated the behaviors of the coil current, the critical current, and the temperature in the superconducting element coils of HTS-SMES. Consequently, the temperature of the superconducting element coils rises up extremely when a large heat is generated at a certain area of one of them by any reason. Moreover, there is a possibility that the shunt resister hardly functions for protection since the coil is burned out due to high inductances and low resistance of the superconducting element coil.

Characterization of the Bacterial Diversity in Indo-West Pacific Loliginid and Sepiolid Squid Light Organs

PubMed Central

Guerrero-Ferreira, Ricardo; Gorman, Clayton; Chavez, Alba A.; Willie, Shantell

2013-01-01

Loliginid and sepiolid squid light organs are known to host a variety of bacterial species from the family Vibrionaceae, yet little is known about the species diversity and characteristics among different host squids. Here we present a broad-ranging molecular and physiological analysis of the bacteria colonizing light organs in loliginid and sepiolid squids from various field locations of the Indo-West Pacific (Australia and Thailand). Our PCR-RFLP analysis, physiological characterization, carbon utilization profiling, and electron microscopy data indicate that loliginid squid in the Indo-West Pacific carry a consortium of bacterial species from the families Vibrionaceae and Photobacteriaceae. This research also confirms our previous report of the presence of Vibrio harveyi as a member of the bacterial population colonizing light organs in loliginid squid. pyrH sequence data were used to confirm isolate identity, and indicates that Vibrio and Photobacterium comprise most of the light organ colonizers of squids from Australia, confirming previous reports for Australian loliginid and sepiolid squids. In addition, combined phylogenetic analysis of PCR-RFLP and 16S rDNA data from Australian and Thai isolates associated both Photobacterium and Vibrio clades with both loliginid and sepiolid strains, providing support that geographical origin does not correlate with their relatedness. These results indicate that both loliginid and sepiolid squids demonstrate symbiont specificity (Vibrionaceae), but their distribution is more likely due to environmental factors that are present during the infection process. This study adds significantly to the growing evidence for complex and dynamic associations in nature and highlights the importance of exploring symbiotic relationships in which non-virulent strains of pathogenic Vibrio species could establish associations with marine invertebrates. PMID:22885637

Fundamental study on the magnetic field control method using multiple HTS coils for Magnetic Drug Delivery System

NASA Astrophysics Data System (ADS)

Hirano, R.; Kim, S. B.; Nakagawa, T.; Tomisaka, Y.; Ueda, H.

2017-07-01

The magnetic drug delivery system (MDDS) is a key technology to reduce the side effects in the medical applications, and the magnetic force control is very important issue in MDDS. In this application, the strength of magnetic field and gradient required to MDDS devices are 54 mT and 5.5 T/m, respectively. We proposed the new magnetic force control system that consists of the multiple racetrack HTS magnets. We can control the magnetic field gradient along the longitudinal direction by the arrangement of the multiple racetrack HTS magnets and operating current of each magnet. When the racetrack HTS magnets were used, the critical current was reduced by the self-magnetic field. Therefore, the shape design of HTS magnet to reduce the magnet field into the surface of HTS tapes was required. Therefore, the electromagnetic analysis based on finite element method (FEM) was carried out to design and optimize the shape of multiple racetrack HTS magnet. We were able to suppress the reduction of critical current by placing the magnetic substance at upper and lower side of the HTS magnets. It was confirmed that obtained maximum values of magnetic field strength and field gradient were 33 mT and 0.18 T/m, respectively.

Progress in American Superconductor's HTS wire and optimization for fault current limiting systems

NASA Astrophysics Data System (ADS)

Malozemoff, Alexis P.

2016-11-01

American Superconductor has developed composite coated conductor tape-shaped wires using high temperature superconductor (HTS) on a flexible substrate with laminated metal stabilizer. Such wires enable many applications, each requiring specific optimization. For example, coils for HTS rotating machinery require increased current density J at 25-50 K. A collaboration with Argonne, Brookhaven and Los Alamos National Laboratories and several universities has increased J using an optimized combination of precipitates and ion irradiation defects in the HTS. Major commercial opportunities also exist to enhance electric power grid resiliency by linking substations with distribution-voltage HTS power cables [10]. Such links provide alternative power sources if one substation's transmission-voltage power is compromised. But they must also limit fault currents which would otherwise be increased by such distribution-level links. This can be done in an HTS cable, exploiting the superconductor-to-resistive transition when current exceeds the wires' critical J. A key insight is that such transitions are usually nonuniform; so the wire must be designed to prevent localized hot spots from damaging the wire or even generating gas bubbles in the cable causing dielectric breakdown. Analysis shows that local heating can be minimized by increasing the composite tape's total thickness, decreasing its total resistance in the normal state and decreasing its critical J. This conflicts with other desirable wire characteristics. Optimization of these conflicting requirements is discussed.

Influence of radius of cylinder HTS bulk on guidance force in a maglev vehicle system

NASA Astrophysics Data System (ADS)

Longcai, Zhang

2014-07-01

Bulk superconductors had great potential for various engineering applications, especially in a high-temperature superconducting (HTS) maglev vehicle system. In such a system, the HTS bulks were always exposed to AC external magnetic field, which was generated by the inhomogeneous surface magnetic field of the NdFeB guideway. In our previous work, it was observed that the guidance force of the YBCO bulk over the NdFeB guideway used in the HTS maglev vehicle system was decayed by the application of the AC external magnetic field. In this paper, we investigated the influence of the radius of the cylinder HTS bulk exposed to an AC magnetic field perturbation on the guidance force in the maglev vehicle system. From the results, it was found that the guidance force was stronger for the bulk with bigger radius and the guidance force decay rates of the bulks were approximately equal despite of the different radius in the maglev vehicle system. Therefore, in order to obtain higher guidance force in the maglev vehicle system, we could use the cylinder HTS bulks with the bigger radius.

Accelerating the introduction of HTS products for a broad range of electric power and industrial applications

NASA Astrophysics Data System (ADS)

Eaton, Russell

2002-01-01

The Department of Energy (DOE), as part of its Superconductivity Program for Electric Systems, is successfully pursuing the development of electric power and industrial devices, incorporating significant high-temperature superconducting (HTS) components or subsystems, through its innovative Superconducting Partnership Initiative (SPI). The objective of the SPI is to accelerate the commercial introduction of the HTS products for a broad range of electric power and industrial applications. DOE's approach to accomplishing the SPI objective is to support cost shared projects carried out by industry led teams. DOE will fund projects to develop HTS devices that are either in (1) the research and development stage (Phase 1), (2) the pre-commercialization stage (Phase II), or (3) the commercial entry stage (Phase III). DOE's industry partners must contribute at least half a project's costs. These teams will include capabilities needed to develop the device as well as to develop the business plan for the commercial product introduction. DOE's partners consist of vertically integrated teams consisting of equipment manufacturers, HTS wire and coil suppliers, national laboratories, and end users, primarily utilities. These partners carry out the multi-year technology development efforts, consisting generally of design, construction, and testing of the HTS system. Finally, commercialization of HTS products will be discussed primarily in terms of benefits these products will have over competing products based upon conventional conductors and the critical need for affordable, practical HTS materials and conductors for these applications. .

Opportunistic acoustic recordings of (potential) orangeback flying squid Sthenoteuthis pteropus in the Central Eastern Atlantic

NASA Astrophysics Data System (ADS)

Peña, Marian; Villanueva, Roger; Escánez, Alejandro; Ariza, Alejandro

2018-03-01

Squids are fast swimmers that are difficult to catch by nets and to record with echosounders in the open ocean. A rare detection of orangeback flying squid Sthenoteuthis pteropus in the Central Eastern Atlantic Ocean off the coast of Senegal was accomplished during the MAFIA oceanographic survey carried out between Brazil and the Canary Islands in April 2015. Although net sampling did not yield any subadult or adult individuals, dozens were visually detected from the vessel jumping out of the water at night and displaying their characteristic dorsal photophore patch. A few squids were caught with fishing lines and identified at the species level. The acoustic echograms revealed distinctive previously unobserved acoustic echotraces that seemed to be caused by those squids, which were the only new species detected at that station (over a bottom depth ranging from 4010 to 5215 m, between 10° 45‧ N 22° 41‧ W and 10° 53‧ N 22° 40‧ W). The acoustic response and swimming behaviour shown by those echotraces reinforced this hypothesis. The (potentially) squid recordings dove rapidly (0.19 m/s to 0.48 m/s) from around 10 m below the mesopelagic fish layer, which had migrated to the subsurface at night (35 m depth), to depths of 70-95 m, and swam upward, apparently attacking fish from below. The morning squid migration to deeper waters (250-300 m) was also recorded acoustically. Downward movements of squid swimming at speeds of 0.22 m/s were calculated from the echogram, while the mesopelagic migrating fish swam at 0.27 m/s reaching 250 m depth. Sv120 - Sv38 averaged 2.7 ± 3.2 dB for the squid echotraces while the mesopelagic layer showed values of -8.8 ± 0.9 dB. These ranges agreed with values in the literature and from theoretical models. This study provides more insight into the migrating behaviour of oceanic squids, a species group that is poorly represented in the acoustic literature due to challenges in studying them.

Low resistance splices for HTS devices and applications

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lalitha, S. L.

This paper discusses the preparation methodology and performance evaluation of low resistance splices made of the second generation (2G) high-temperature superconductor (HTS). These splices are required in a broad spectrum of HTS devices including a large aperture, high-field solenoid built in the laboratory to demonstrate a superconducting magnetic energy storage (SMES) device. Several pancake coils are assembled in the form of a nested solenoid, and each coil requires a hundred meters or more of 2G (RE)BCO tape. However, commercial availability of this superconductor with a very uniform physical properties is currently limited to shorter piece lengths. This necessitates us havingmore » splices to inter-connect the tape pieces within a pancake coil, between adjacent pancake coils, and to attach HTS current leads to the magnet assembly. As a part of the optimization and qualification of splicing process, a systematic study was undertaken to analyze the electrical performance of splices in two different configurations suitable for this magnet assembly: lap joint and spiral joint. The electrical performance is quantified in terms of the resistance of splices estimated from the current-voltage characteristics. Finally, It has been demonstrated that a careful application of this splicing technique can generate lap joints with resistance less than 1 nΩ at 77 K.« less

Low resistance splices for HTS devices and applications

DOE PAGES

Lalitha, S. L.

2017-06-30

This paper discusses the preparation methodology and performance evaluation of low resistance splices made of the second generation (2G) high-temperature superconductor (HTS). These splices are required in a broad spectrum of HTS devices including a large aperture, high-field solenoid built in the laboratory to demonstrate a superconducting magnetic energy storage (SMES) device. Several pancake coils are assembled in the form of a nested solenoid, and each coil requires a hundred meters or more of 2G (RE)BCO tape. However, commercial availability of this superconductor with a very uniform physical properties is currently limited to shorter piece lengths. This necessitates us havingmore » splices to inter-connect the tape pieces within a pancake coil, between adjacent pancake coils, and to attach HTS current leads to the magnet assembly. As a part of the optimization and qualification of splicing process, a systematic study was undertaken to analyze the electrical performance of splices in two different configurations suitable for this magnet assembly: lap joint and spiral joint. The electrical performance is quantified in terms of the resistance of splices estimated from the current-voltage characteristics. Finally, It has been demonstrated that a careful application of this splicing technique can generate lap joints with resistance less than 1 nΩ at 77 K.« less

On-site detection of packaged squid freshness

NASA Astrophysics Data System (ADS)

Ahmad, Noor Azizah; Heng, Lee Yook; Salam, Faridah; Hanifah, Sharina Abu

2018-04-01

The development of indicator label for detection of total volatile basic nitrogen (TVB-N) is described. Dye extract from edible plants containing anthocyanins was immobilized onto iota-carrageenan as polymer matrix. TVB-N detection worked based on pH increase as the basic deterioration volatile amines generated in the package headspace. Results showed that the indicator label has changed color from blue to green after 12 hours of storage at ambient conditions. The TVB-N value was 38.9648 mg /100 g which is exceeded of acceptability level for seafood products. The pH value of squid flesh has also increased during storage. The colour values of L * and a * negative increases while b* negative decrease with increasing storage time. The indicator label is potentially used as freshness indicator for squid at ambient conditions.

Identifying Pelagic Habitat Hotspots of Neon Flying Squid in the Temperate Waters of the Central North Pacific

PubMed Central

Alabia, Irene D.; Saitoh, Sei-Ichi; Mugo, Robinson; Igarashi, Hiromichi; Ishikawa, Yoichi; Usui, Norihisa; Kamachi, Masafumi; Awaji, Toshiyuki; Seito, Masaki

2015-01-01

We identified the pelagic habitat hotspots of the neon flying squid (Ommastrephes bartramii) in the central North Pacific from May to July and characterized the spatial patterns of squid aggregations in relation to oceanographic features such as mesoscale oceanic eddies and the Transition Zone Chlorophyll-a Front (TZCF). The data used for the habitat model construction and analyses were squid fishery information, remotely-sensed and numerical model-derived environmental data from May to July 1999–2010. Squid habitat hotspots were deduced from the monthly Maximum Entropy (MaxEnt) models and were identified as regions of persistent high suitable habitat across the 12-year period. The distribution of predicted squid habitat hotspots in central North Pacific revealed interesting spatial and temporal patterns likely linked with the presence and dynamics of oceanographic features in squid’s putative foraging grounds from late spring to summer. From May to June, the inferred patches of squid habitat hotspots developed within the Kuroshio-Oyashio transition zone (KOTZ; 37–40°N) and further expanded north towards the subarctic frontal zone (SAFZ; 40–44°N) in July. The squid habitat hotspots within the KOTZ and areas west of the dateline (160°W-180°) were likely influenced and associated with the highly dynamic and transient oceanic eddies and could possibly account for lower squid suitable habitat persistence obtained from these regions. However, predicted squid habitat hotspots located in regions east of the dateline (180°-160°W) from June to July, showed predominantly higher squid habitat persistence presumably due to their proximity to the mean position of the seasonally-shifting TZCF and consequent utilization of the highly productive waters of the SAFZ. PMID:26571118

Squid Dissection: From Pen to Ink.

ERIC Educational Resources Information Center

Brown, Cindy; Kisiel, Jim

2003-01-01

Introduces students to dissection, which is an important part of scientific discovery. Students not only gain an understanding of the anatomy of a squid, but also develop a sense of responsibility and respect for the animal that they are using as a learning tool. (Author/SOE)

The Role of HTS in Drug Discovery at the University of Michigan

PubMed Central

Larsen, Martha J.; Larsen, Scott D.; Fribley, Andrew; Grembecka, Jolanta; Homan, Kristoff; Mapp, Anna; Haak, Andrew; Nikolovska-Coleska, Zaneta; Stuckey, Jeanne A.; Sun, Duxin

2014-01-01

High throughput screening (HTS) is an integral part of a highly collaborative approach to drug discovery at the University of Michigan. The HTS lab is one of four core centers that provide services to identify, produce, screen and follow-up on biomedical targets for faculty. Key features of this system are: protein cloning and purification, protein crystallography, small molecule and siRNA HTS, medicinal chemistry and pharmacokinetics. Therapeutic areas that have been targeted include anti-bacterial, metabolic, neurodegenerative, cardiovascular, anti-cancer and anti-viral. The centers work in a coordinated, interactive environment to affordably provide academic investigators with the technology, informatics and expertise necessary for successful drug discovery. This review provides an overview of these centers at the University of Michigan, along with case examples of successful collaborations with faculty. PMID:24409957

Imaging of current density distributions with a Nb weak-link scanning nano-SQUID microscope

PubMed Central

Shibata, Yusuke; Nomura, Shintaro; Kashiwaya, Hiromi; Kashiwaya, Satoshi; Ishiguro, Ryosuke; Takayanagi, Hideaki

2015-01-01

Superconducting quantum interference devices (SQUIDs) are accepted as one of the highest magnetic field sensitive probes. There are increasing demands to image local magnetic fields to explore spin properties and current density distributions in a two-dimensional layer of semiconductors or superconductors. Nano-SQUIDs have recently attracting much interest for high spatial resolution measurements in nanometer-scale samples. Whereas weak-link Dayem Josephson junction nano-SQUIDs are suitable to miniaturization, hysteresis in current-voltage (I-V) characteristics that is often observed in Dayem Josephson junction is not desirable for a scanning microscope. Here we report on our development of a weak-link nano-SQUIDs scanning microscope with small hysteresis in I-V curve and on reconstructions of two-dimensional current density vector in two-dimensional electron gas from measured magnetic field. PMID:26459874

Imaging of current density distributions with a Nb weak-link scanning nano-SQUID microscope

NASA Astrophysics Data System (ADS)

Shibata, Yusuke; Nomura, Shintaro; Kashiwaya, Hiromi; Kashiwaya, Satoshi; Ishiguro, Ryosuke; Takayanagi, Hideaki

2015-10-01

Superconducting quantum interference devices (SQUIDs) are accepted as one of the highest magnetic field sensitive probes. There are increasing demands to image local magnetic fields to explore spin properties and current density distributions in a two-dimensional layer of semiconductors or superconductors. Nano-SQUIDs have recently attracting much interest for high spatial resolution measurements in nanometer-scale samples. Whereas weak-link Dayem Josephson junction nano-SQUIDs are suitable to miniaturization, hysteresis in current-voltage (I-V) characteristics that is often observed in Dayem Josephson junction is not desirable for a scanning microscope. Here we report on our development of a weak-link nano-SQUIDs scanning microscope with small hysteresis in I-V curve and on reconstructions of two-dimensional current density vector in two-dimensional electron gas from measured magnetic field.

Routine clinical heart examinations using SQUID magnetocardiography at University of Tsukuba Hospital

NASA Astrophysics Data System (ADS)

Inaba, T.; Nakazawa, Y.; Yoshida, K.; Kato, Y.; Hattori, A.; Kimura, T.; Hoshi, T.; Ishizu, T.; Seo, Y.; Sato, A.; Sekiguchi, Y.; Nogami, A.; Watanabe, S.; Horigome, H.; Kawakami, Y.; Aonuma, K.

2017-11-01

A 64-channel Nb-based DC-SQUID magnetocardiography (MCG) system was installed at the University of Tsukuba Hospital (UTH) in March 2007 after obtaining Japanese pharmaceutical approval and insurance reimbursement approval. In the period between 2008 and 2016, the total number of patients was 10 085. The heart diseases diagnosed in fetuses as well as adults are mainly atrial arrhythmia, abnormal repolarization, ventricular arrhythmia, and fetal arrhythmia. In most cases of insufficient diagnostic accuracy with electrocardiography, SQUID MCG precisely revealed these heart diseases as an abnormal electrical current distribution. Based on success in routine examinations, SQUID MCG is now an indispensable clinical instrument with diagnostic software tuned up during routine use at UTH.

Controlled and in situ target strengths of the jumbo squid Dosidicus gigas and identification of potential acoustic scattering sources.

PubMed

Benoit-Bird, Kelly J; Gilly, William F; Au, Whitlow W L; Mate, Bruce

2008-03-01

This study presents the first target strength measurements of Dosidicus gigas, a large squid that is a key predator, a significant prey, and the target of an important fishery. Target strength of live, tethered squid was related to mantle length with values standardized to the length squared of -62.0, -67.4, -67.9, and -67.6 dB at 38, 70, 120, and 200 kHz, respectively. There were relatively small differences in target strength between dorsal and anterior aspects and none between live and freshly dead squid. Potential scattering mechanisms in squid have been long debated. Here, the reproductive organs had little effect on squid target strength. These data support the hypothesis that the pen may be an important source of squid acoustic scattering. The beak, eyes, and arms, probably via the sucker rings, also play a role in acoustic scattering though their effects were small and frequency specific. An unexpected source of scattering was the cranium of the squid which provided a target strength nearly as high as that of the entire squid though the mechanism remains unclear. Our in situ measurements of the target strength of free-swimming squid support the use of the values presented here in D. gigas assessment studies.

Size increment of jumbo flying squid Dosidicus gigas mature females in Peruvian waters, 1989-2004

NASA Astrophysics Data System (ADS)

Argüelles, Juan; Tafur, Ricardo; Taipe, Anatolio; Villegas, Piero; Keyl, Friedeman; Dominguez, Noel; Salazar, Martín

2008-10-01

Changes in population structure of the jumbo flying squid Dosidicus gigas in Peruvian waters were studied based on size-at-maturity from 1989 to 2004. From 1989 to 1999, mature squid belonging to the medium-sized group prevailed, but from 2001 on, mature squids were larger. This change is not related to the changes in sea surface temperature and we hypothesized that it was caused by the population increase of mesopelagic fishes as prey.

Effects of the dipolar form of phloretin on potassium conductance in squid giant axons.

PubMed Central

Strichartz, G R; Oxford, G S; Ramon, F

1980-01-01

The effects of phloretin on membrane ionic conductances have been studied in the giant axon of the squid, Loligo pealei. Phloretin reversibly suppresses the potassium and sodium conductances and modifies their dependence on membrane potential (Em). Its effects on the potassium conductance (GK) are much greater than on the sodium conductance; no effects on sodium inactivation are observed. Internal perfusion of phloretin produces both greater shifts in GK(Em) and greater reductions maximum GK than does external perfusion; the effect of simultaneous internal and external perfusion is little greater than that of internal perfusion alone. Lowering the internal pH, which favors the presence of the neutral species of weakly acidic phloretin (pKa 7.4), potentiates the actions of internally perfused phloretin. Other organic cations with dipole moments similar to phloretin's have little effect on either potassium or sodium conductances in squid axons. These results can be explained by either of two mechanisms; on postulates a phloretin "receptor" near the voltage sensor component of the potassium channel which is accessible to drug molecules applied at either the outer or inner membrane surface and is much more sensitive to the neutral than the negatively charged form of the drug. The other mechanism proposes that neutral phloretin molecules are dispersed in an ordered array in the membrane interior, producing a diffuse dipole field which modifies potassium channel gating. Different experimental results support these two mechanisms, and neither hypothesis can be disproven. PMID:6266534

Optimization of HTS superconducting magnetic energy storage magnet volume

NASA Astrophysics Data System (ADS)

Korpela, Aki; Lehtonen, Jorma; Mikkonen, Risto

2003-08-01

Nonlinear optimization problems in the field of electromagnetics have been successfully solved by means of sequential quadratic programming (SQP) and the finite element method (FEM). For example, the combination of SQP and FEM has been proven to be an efficient tool in the optimization of low temperature superconductors (LTS) superconducting magnetic energy storage (SMES) magnets. The procedure can also be applied for the optimization of HTS magnets. However, due to a strongly anisotropic material and a slanted electric field, current density characteristic high temperature superconductors HTS optimization is quite different from that of the LTS. In this paper the volumes of solenoidal conduction-cooled Bi-2223/Ag SMES magnets have been optimized at the operation temperature of 20 K. In addition to the electromagnetic constraints the stress caused by the tape bending has also been taken into account. Several optimization runs with different initial geometries were performed in order to find the best possible solution for a certain energy requirement. The optimization constraints describe the steady-state operation, thus the presented coil geometries are designed for slow ramping rates. Different energy requirements were investigated in order to find the energy dependence of the design parameters of optimized solenoidal HTS coils. According to the results, these dependences can be described with polynomial expressions.

Effects of Storage Temperature on the Quality of Frozen Squid

NASA Astrophysics Data System (ADS)

Kozima, Tsuneo; Ohtaka, Tateo

Squid ( Todarodes pacificus) , which is one of the main Japanzse coastal fish , was frozen under commercial condition after catch immediately and stored at -18 , -23 , -30 °C and 40 °C for 12 months. During storage the quality was measured by determining amount of free drip , water-holding capacity of muscle , weight ratio of cooking loss , histoligical feature of frozen and thawed muscle , and organoleptic test at regular intervals , each 2 months. Storage life of frozen squid was 12 months at below -18 °C.

A shot in the dark: same-sex sexual behaviour in a deep-sea squid.

PubMed

Hoving, Hendrik J T; Bush, Stephanie L; Robison, Bruce H

2012-04-23

Little is known about the reproductive habits of deep-living squids. Using remotely operated vehicles in the deep waters of the Monterey Submarine Canyon, we have found evidence of mating, i.e. implanted sperm packages, on similar body locations in males and females of the rarely seen mesopelagic squid Octopoteuthis deletron. Equivalent numbers of both sexes were found to have mated, indicating that male squid routinely and indiscriminately mate with both males and females. Most squid species are short-lived, semelparous (i.e. with a single, brief reproductive period) and promiscuous. In the deep, dark habitat where O. deletron lives, potential mates are few and far between. We suggest that same-sex mating behaviour by O. deletron is part of a reproductive strategy that maximizes success by inducing males to indiscriminately and swiftly inseminate every conspecific that they encounter.

Temperature Distribution and Critical Current of Long HTS Cables Cooled with Subcooled Liquid Nitrogen

NASA Astrophysics Data System (ADS)

Vyatkin, V. S.; Ivanov, Y. V.; Watanabe, H.; Chikumoto, N.; Yamaguchi, S.

2017-07-01

Cooling of the long HTS power transmission lines performs by pumping of subcooled liquid nitrogen (LN2) along the cable. The temperature of LN2 along the cable increases due to the heat losses of the cryostat and heat generation in the HTS cable. The experiment using test cable line in Ishikari shows that flow rate of 35 L/min retains increasing of LN2 temperature by 1 K per 1 km of length. The technology when the back flow of LN2 cools the radiation shield surrounding the cable pipe is also applied in Ishikari-2 project. In this case the ambient heat flow into cable pipe is 50 times less than that without radiation shield. Back flow of LN2 removes almost all heat coming from the environment. When transport current is close to the critical value the Joule heat of HTS cable is significant. This heat additionally increases the temperature of LN2 flowing along the HTS cable. Near the outlet the temperature of HTS cable is maximal and the local critical current is minimal. The current matching critical current criterion of average electrical field of E 0 = 10-4 V/m provides the voltage drop and significant Joule heat at the hot end of the cable. It can lead the damage of the cable. The present work contains analysis of temperature distribution along the cable and the way to achieve the fail-safe operation of long HTS cable cooled by subcooled LN2. We also performed extrapolation of obtained results for several times longer cable lines by decreasing the LN2 flow rate.

Performance of the BG1Luc ER TA method in a qHTS format.

PubMed

Ceger, Patricia; Allen, David; Huang, Ruili; Xia, Menghang; Casey, Warren

2015-01-01

In 2012, the BG1Luc4E2 estrogen receptor (ER) transactivation (TA) method (BG1Luc ER TA) was accepted by U.S. regulatory agencies and the Organisation for Economic Co-operation and Development to detect substances with ER agonist activity. The method is now part of the Tier 1 testing battery in the Environmental Protection Agency's Endocrine Disruptor Screening Program. The BG1Luc ER TA method uses the BG1 ovarian cell line that endogenously expresses full-length ER (α and β) and is stably transfected with a plasmid containing four estrogen responsive elements upstream of a luciferase reporter gene. To allow increased throughput and testing efficiency, the BG1Luc ER TA ("BG1 manual") method was adapted for quantitative high-throughput screening (BG1 qHTS) in the U.S. Tox21 testing program. The BG1 qHTS test method was used to test approximately 10,000 chemicals three times each, and concentration-response data (n=15) were analyzed to evaluate test method performance. The balanced accuracy of the BG1 qHTS test method (97% [32/33]) was determined by comparing results to ER TA performance standards for the BG1 manual method. Concordance between the BG1 manual and qHTS methods was 92% (57/62) when calculated for a larger set of non-reference chemicals tested in both methods. These data demonstrate that the performance of the BG1 qHTS is similar to the currently accepted BG1 manual method, thereby establishing the utility of the BG1 qHTS method for identifying ER active environmental chemicals.

Molecular identification of anisakid nematodes third stage larvae isolated from common squid ( Todarodes pacificus) in Korea

NASA Astrophysics Data System (ADS)

Setyobudi, Eko; Jeon, Chan-Hyeok; Choi, Kwangho; Lee, Sung Il; Lee, Chung Il; Kim, Jeong-Ho

2013-06-01

The occurrence of Genus Anisakis nematode larvae in marine fishes and cephalopods is epidemiologically important because Anisakis simplex larval stage can cause a clinical disease in humans when infected hosts are consumed raw. Common squid ( Todarodes pacificus) from Korean waters were investigated for anisakid nematodes infection during 2009˜2011. In total, 1,556 larvae were collected from 615 common squids and 732 of them were subsequently identified by PCR-RFLP analysis of ITS rDNA. Depending on the sampling locations, the nematode larvae from common squid showed different prevalence, intensity and species distribution. A high prevalence (P) and mean intensity (MI) of infection were observed in the Yellow Sea (n = 250, P = 86.0%, MI = 5.99 larvae/host) and the southern sea of Korea (n = 126, P = 57.1%, MI = 3.36 larvae/host). Anisakis pegreffii was dominantly found in common squid from the southern sea (127/ 140, 90.7%) and the Yellow Sea (561/565, 98.9%). In contrast, the P and MI of infection were relatively low in the East Sea (n = 239, P = 8.37%, MI = 1.25 larvae/host). A. pegreffii was not found from the East Sea and 52.0% (13/25) of the nematodes were identified as A. simplex. Most of them were found in the body cavity or digestive tract of common squid, which are rarely consumed raw by humans. Considering the differenences in anisakid nematode species distribution and their microhabitat in common squid, it remains unclear whether common squid plays an important role in the epidemiology of human anisakis infection in Korea. Further extensive identification of anisakid nematodes in common squid, with geographical and seasonal information will be necessary.

Experiences in implementing uHTS--cutting edge technology meets the real world.

PubMed

Gribbon, Philip; Schaertl, Sabine; Wickenden, Malcolm; Williams, Gareth; Grimley, Rachel; Stuhmeier, Frank; Preckel, Hartwig; Eggeling, Christian; Kraemer, Joachim; Everett, Jeremy; Keighley, Wilma W; Sewing, Andreas

2004-01-01

Driven by growing corporate compound files, the demands of target biology, and attempts to cut cost, the number of solutions to HTS has spiralled. In quick succession new assay technologies and screening platforms are appearing on the market, with the promise of screening faster than ever in low volume high density formats whilst providing high quality data. Within this world of rapid change, Pfizer has applied cutting edge technology to HTS by introducing screening in 1 microl formats utilising single molecule detection technology. Instead of resource intensive in-house development, Pfizer entered into a collaboration with Evotec OAI / Evotec Technologies and introduced their Mark-II EVOscreen platform. In this article we will outline the benefits of the approach taken at Pfizer, Sandwich, and introduce the Mark-II EVOscreen platform, illustrating the potential but also possible pitfalls of HTS miniaturisation.

Development of a HTS transceiver sub-system for 3G mobile communication TD-SCDMA base station

NASA Astrophysics Data System (ADS)

Zhang, Xueqiang; He, Xiaofeng; Wang, Yuehui; Duan, Tao; Wang, Guizhen; Zhang, Yan; Li, Chunguang; Zhang, Qiang; Li, Hong; He, Yusheng

2010-02-01

A prototype of a high temperature superconducting (HTS) transceiver sub-system for applications in a TD-SCDMA, one of the third generation (3G) communication standards, base station has been developed. Both the HTS sub-system and the conventional counterpart have been implemented into a TD-SCDMA commercial communication network and comparison test studies were carried out. The measured results showed that the HTS sub-system could remarkably improve the RF performance of both transmitting and receiving chains.

Cadmium content in fresh and canned squid (Loligo opalescens) from the Pacific coastal waters of California (USA).

PubMed

Galitsopoulou, A; Georgantelis, D; Kontominas, M G

2009-01-01

Cadmium (Cd) levels were determined in 70 samples of mantle tissue and 70 whole individual squid (Loligo opalescens; commercially known as California squid). Samples were collected from the coastal zones of California (USA) during the period 2007/2008. To further investigate consumer exposure to processed fishery products, cadmium concentration was also determined in 200 canned samples of squid. Cd concentrations in raw mantle were low, between 0.01 and 0.29 mg kg(-1) and below the tolerance limit of current regulations (1 mg kg(-1)). Respective concentrations in whole individuals were significantly higher, ranging from 0.51 to 1.18 mg kg(-1), attributed to the presence of the visceral portion in whole squid samples. Cd concentrations varied in relation to age and sex of squid, indicating that several physiological factors may influence accumulation. Furthermore, canning of squid substantially enhanced Cd levels. Cd concentration ranged 0.17-0.67 mg kg(-1) in canned mantle tissue and 0.86-2.07 mg kg(-1) in canned whole squid samples, due to both concentration after canning and movement of the metal between different tissues. Several biological compounds, including metallothioneins, nucleic acids and enzymes, may affect Cd concentrations in commercial fishery products.

Quench Detection and Protection of an HTS Coil

NASA Astrophysics Data System (ADS)

Sheehan, Evan; Pfotenhauer, John; Miller, Franklin; Christianson, Owen

2017-12-01

A pulsed, modular HTS magnet for energy storage applications was constructed and tested. Charge and discharge pulses were accomplished in about 1 second. A recuperative cryogenic cooling system supplies 42 to 80 Kelvin helium gas to the magnet. A practical solution to overvoltage and overcurrent protection has been implemented digitally using LabVIEW. Voltages as little as 46 μV greater than the expected value trigger the protection system, which stops the pulse profile and begins an immediate current ramp down to zero over 1 second. The protection system has displayed its effectiveness in HTS transition detection and damage prevention. Experimentation has demonstrated that current pulses on the order of seconds with amplitudes of up to 110 Amps can be achieved for extended periods. Higher currents produce joint heating in excess of the available cooling from the existing cryogenic system.

HTS Fabry-Perot resonators for the far infrared

NASA Astrophysics Data System (ADS)

Keller, Philipp; Prenninger, Martin; Pechen, Evgeny V.; Renk, Karl F.

1996-06-01

We report on far infrared (FIR) Fabry-Perot resonators (FPR) with high temperature superconductor (HTS) thin films as mirrors. For the fabrication of FPR we use two parallel MgO plates covered with YBa2Cu3O7-delta thin films on adjacent sides. We have measured the far-infrared transmissivity at 10 K with a Fourier transform infrared spectrometer. Very sharp resonances can be observed for frequencies below 6 THz where the MgO is transparent. The finesse (width of the first order resonance) is comparable to the FPR with metallic meshes as reflectors that are applied in the FIR spectroscopy and astronomy. We have also shown that thin films of gold are not adequate substitute to HTS thin films and not suitable for the fabrication of high-quality FPR due to the ohmic losses.

Behavioral ecology of jumbo squid (Dosidicus gigas) in relation to oxygen minimum zones

NASA Astrophysics Data System (ADS)

Stewart, Julia S.; Field, John C.; Markaida, Unai; Gilly, William F.

2013-10-01

Habitat utilization, behavior and food habits of the jumbo or Humboldt squid, Dosidicus gigas, were compared between an area recently inhabited in the northern California Current System (CCS) and a historically established area of residence in the Gulf of California (GOC). Low dissolved oxygen concentrations at midwater depths define the oxygen minimum zone (OMZ), an important environmental feature in both areas. We analyzed vertical diving behavior and diet of D. gigas and hydrographic properties of the water column to ascertain the extent to which squid utilized the OMZ in the two areas. The upper boundary of the OMZ has been shoaling in recent decades in the CCS, and this phenomenon has been proposed to vertically compress the pelagic environment inhabited by aerobic predators. A shoaling OMZ will also bring mesopelagic communities into a depth range with more illumination during daytime, making these organisms more vulnerable to predation by visual predators (i.e. jumbo squid). Because the OMZ in the GOC is considerably shallower than in the CCS, our study provides insight into the behavioral plasticity of jumbo squid and how they may respond to a shoaling OMZ in the CCS. We propose that shoaling OMZs are likely to be favorable to jumbo squid and could be a key indirect factor behind the recent range expansion of this highly migratory predator.

Measurement of SQUID noise levels for SuperCDMS SNOLAB detectors - Final Paper

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lee, Maxwell

SuperCDMS SNOLAB is a second generation direct dark matter search. In the SuperCDMS SNOLAB experiment, detectors are able to pick up from signals from dark matter nuclear recoil interactions which occur inside the bulk of the detectors. These interactions produce both phonon and charge signals. HEMTs read out charge signals whereas TES are used to detect phonon signals which are then read out by SQUID amplifiers. SQUID amplifiers must add negligible noise to the TES intrinsic noise which has been previously measured and is approximately 50pA/√Hz down to 100Hz for ease of signal distinguishability in dark matter nuclear interactions. Themore » intrinsic noise level of the SQUID was tested in the SLAC 300mK fridge and determined to provide adequately low levels of noise with a floor of approximately 3pA/√Hz. Furthermore, a 10x amplifier was tested for addition of extraneous noise. This noise was investigated with and without this amplifier, and it was found that it did not add a significant amount of noise to the intrinsic SQUID noise.« less

Loss measurement and analysis for the prototype generator with HTS stator and permanent magnet rotor

NASA Astrophysics Data System (ADS)

Song, Peng; Qu, Timing; Yu, Xiaoyu; Li, Longnian; Gu, Chen; Li, Xiaohang; Wang, Dewen; Hu, Boping; Chen, Duxing; Han, Zhenghe

2013-11-01

A prototype HTS synchronous generator with a permanent magnet rotor and HTS armature windings was developed. The rated armature frequency is 10 Hz. The cryogenic Dewar is tightly surrounded outside the iron core. Both HTS coils and the iron core were cooled by using conduction cooling method. During the process of no-load running, the no-load loss power data were obtained through the torque measurement. The temperature evolution characteristics of the stator was measured by PT-100 temperature sensors. These results show that the no-load loss power at around 77 K are much larger than that at room temperature. The possible reason for the no-load loss increment is discussed. The ac loss power of one individual HTS coil used in this generator was also tested. Compared with the iron loss power, the ac loss power is rather small and could be neglected.

Non-resonant interactions between superconducting circuits coupled through a dc-SQUID

NASA Astrophysics Data System (ADS)

Jin, X. Y.; Lecocq, F.; Cicak, K.; Kotler, S. S.; Peterson, G. A.; Teufel, J. D.; Aumentado, J.; Simmonds, R. W.

We use a flux-biased direct current superconducting quantum interference device (dc-SQUID) to generate non-resonant tunable interactions between transmon qubits and resonators modes. By modulating the flux to the dc-SQUID, we can create an interaction with variable coupling rates from zero to greater than 100 MHz. We explore this system experimentally and describe its operation. Parametric coupling is important for constructing larger coupled systems, useful for both quantum information architectures and quantum simulators.

Magnetic fields end-face effect investigation of HTS bulk over PMG with 3D-modeling numerical method

NASA Astrophysics Data System (ADS)

Qin, Yujie; Lu, Yiyun

2015-09-01

In this paper, the magnetic fields end-face effect of high temperature superconducting (HTS) bulk over a permanent magnetic guideway (PMG) is researched with 3D-modeling numerical method. The electromagnetic behavior of the bulk is simulated using finite element method (FEM). The framework is formulated by the magnetic field vector method (H-method). A superconducting levitation system composed of one rectangular HTS bulk and one infinite long PMG is successfully investigated using the proposed method. The simulation results show that for finite geometrical HTS bulk, even the applied magnetic field is only distributed in x-y plane, the magnetic field component Hz which is along the z-axis can be observed interior the HTS bulk.

Apparatus for detecting a magnetic anomaly contiguous to remote location by squid gradiometer and magnetometer systems

DOEpatents

Overton, Jr., William C.; Steyert, Jr., William A.

1984-01-01

A superconducting quantum interference device (SQUID) magnetic detection apparatus detects magnetic fields, signals, and anomalies at remote locations. Two remotely rotatable SQUID gradiometers may be housed in a cryogenic environment to search for and locate unambiguously magnetic anomalies. The SQUID magnetic detection apparatus can be used to determine the azimuth of a hydrofracture by first flooding the hydrofracture with a ferrofluid to create an artificial magnetic anomaly therein.

Flux pumping for non-insulated and metal-insulated HTS coils

NASA Astrophysics Data System (ADS)

Ma, Jun; Geng, Jianzhao; Coombs, T. A.

2018-01-01

High-temperature superconducting (HTS) coils wound from coated conductors without turn-to-turn insulation (non-insulated (NI) coils) have been proven with excellent electrical and thermal performances. However, the slow charging of NI coils has been a long-lasting problem. In this work, we explore using a transformer-rectifier HTS flux pump to charge an NI coil and a metal-insulated coil. The charging performance comparison is made between different coils. Comprehensive study is done to thoroughly understand the electrical-magnetic transience in charging these coils. We will show that the low-voltage high-current flux pump is especially suitable for charging NI coils with very low characteristic resistance.

Material properties of Pacific hake, Humboldt squid, and two species of myctophids in the California Current.

PubMed

Becker, Kaylyn N; Warren, Joseph D

2015-05-01

Material properties of the flesh from three fish species (Merluccius productus, Symbolophorus californiensis, and Diaphus theta), and several body parts of the Humboldt squid (Dosidicus gigas) collected from the California Current ecosystem were measured. The density contrast relative to seawater varied within and among taxa for fish flesh (0.9919-1.036), squid soft body parts (mantle, arms, tentacle, braincase, eyes; 1.009-1.057), and squid hard body parts (beak and pen; 1.085-1.459). Effects of animal length and environmental conditions on nekton density contrast were investigated. The sound speed contrast relative to seawater varied within and among taxa for fish flesh (0.986-1.027) and Humboldt squid mantle and braincase (0.937-1.028). Material properties in this study are similar to values from previous studies on species with similar life histories. In general, the sound speed and density of soft body parts of fish and squid were 1%-3% and 1%-6%, respectively, greater than the surrounding seawater. Hard parts of the squid were significantly more dense (6%-46%) than seawater. The material properties reported here can be used to improve target strength estimates from acoustic scattering models, which could increase the accuracy of biomass estimates from acoustic surveys for these nekton.

Detection of buried magnetic objects by a SQUID gradiometer system

NASA Astrophysics Data System (ADS)

Meyer, Hans-Georg; Hartung, Konrad; Linzen, Sven; Schneider, Michael; Stolz, Ronny; Fried, Wolfgang; Hauspurg, Sebastian

2009-05-01

We present a magnetic detection system based on superconducting gradiometric sensors (SQUID gradiometers). The system provides a unique fast mapping of large areas with a high resolution of the magnetic field gradient as well as the local position. A main part of this work is the localization and classification of magnetic objects in the ground by automatic interpretation of geomagnetic field gradients, measured by the SQUID system. In accordance with specific features the field is decomposed into segments, which allow inferences to possible objects in the ground. The global consideration of object describing properties and their optimization using error minimization methods allows the reconstruction of superimposed features and detection of buried objects. The analysis system of measured geomagnetic fields works fully automatically. By a given surface of area-measured gradients the algorithm determines within numerical limits the absolute position of objects including depth with sub-pixel accuracy and allows an arbitrary position and attitude of sources. Several SQUID gradiometer data sets were used to show the applicability of the analysis algorithm.

Cosmological flux noise and measured noise power spectra in SQUIDs

PubMed Central

Beck, Christian

2016-01-01

The understanding of the origin of 1/f magnetic flux noise commonly observed in superconducting devices such as SQUIDs and qubits is still a major unsolved puzzle. Here we discuss the possibility that a significant part of the observed low-frequency flux noise measured in these devices is ultimately seeded by cosmological fluctuations. We consider a theory where a primordial flux noise field left over in unchanged form from an early inflationary or quantum gravity epoch of the universe intrinsically influences the phase difference in SQUIDs and qubits. The perturbation seeds generated by this field can explain in a quantitatively correct way the form and amplitude of measured low-frequency flux noise spectra in SQUID devices if one takes as a source of fluctuations the primordial power spectrum of curvature fluctuations as measured by the Planck collaboration. Our theoretical predictions are in excellent agreement with recent low-frequency flux noise measurements of various experimental groups. Magnetic flux noise, so far mainly considered as a nuisance for electronic devices, may thus contain valuable information about fluctuation spectra in the very early universe. PMID:27320418

Cosmological flux noise and measured noise power spectra in SQUIDs.

PubMed

Beck, Christian

2016-06-20

The understanding of the origin of 1/f magnetic flux noise commonly observed in superconducting devices such as SQUIDs and qubits is still a major unsolved puzzle. Here we discuss the possibility that a significant part of the observed low-frequency flux noise measured in these devices is ultimately seeded by cosmological fluctuations. We consider a theory where a primordial flux noise field left over in unchanged form from an early inflationary or quantum gravity epoch of the universe intrinsically influences the phase difference in SQUIDs and qubits. The perturbation seeds generated by this field can explain in a quantitatively correct way the form and amplitude of measured low-frequency flux noise spectra in SQUID devices if one takes as a source of fluctuations the primordial power spectrum of curvature fluctuations as measured by the Planck collaboration. Our theoretical predictions are in excellent agreement with recent low-frequency flux noise measurements of various experimental groups. Magnetic flux noise, so far mainly considered as a nuisance for electronic devices, may thus contain valuable information about fluctuation spectra in the very early universe.

Kilopixel Pop-Up Bolometer Arrays for the Atacama Cosmology Telescope

NASA Technical Reports Server (NTRS)

Chervenak, J. A.; Wollack, E.; Henry, R.; Moseley, S. H.; Niemack, M.; Staggs, S.; Page, L.; Doriese, R.; Hilton, G. c.; Irwin, K. D.

2007-01-01

The recently deployed Atacama Cosmology Telescope (ACT) anticipates first light on its kilopixel array of close-packed transition-edge-sensor bolometers in November of 2007. The instrument will represent a full implementation of the next-generation, large format arrays for millimeter wave astronomy that use superconducting electronics and detectors. Achieving the practical construction of such an array is a significant step toward producing advanced detector arrays for future SOFIA instruments. We review the design considerations for the detector array produced for the ACT instrument. The first light imager consists of 32 separately instrumented 32-channel pop-up bolometer arrays (to create a 32x32 filled array of mm-wave sensors). Each array is instrumented with a 32-channel bias resistor array, Nyquist filter array, and time-division SQUID multiplexer. Each component needed to be produced in relatively large quantities with suitable uniformity to meet tolerances for array operation. An optical design was chosen to maximize absorption at the focal plane while mitigating reflections and stray light. The pop-up geometry (previously implemented with semiconducting detectors and readout on the SHARC II and HAWC instruments) enabled straightforward interface of the superconducting bias and readout circuit with the 2D array of superconducting bolometers. The array construction program balanced fabrication challenges with assembly challenges to deliver the instrument in a timely fashion. We present some of the results of the array build and characterization of its performance.

Numerical study on AC loss reduction of stacked HTS tapes by optimal design of flux diverter

NASA Astrophysics Data System (ADS)

Liu, Guole; Zhang, Guomin; Jing, Liwei; Yu, Hui

2017-12-01

High temperature superconducting (HTS) coils are key parts of many AC applications, such as generators, superconducting magnetic energy storage and transformers. AC loss reduction in HTS coils is essential for the commercialization of these HTS devices. Magnetic material is generally used as the flux diverter in an effort to reduce the AC loss in HTS coils. To achieve the greatest reduction in the AC loss of the coils, the flux diverter should be made of a material with low loss and high saturated magnetic density, and the optimization of the geometric size and location of the flux diverter is required. In this paper, we chose Ni-alloy as the flux diverter, which can be processed into a specific shape and size. The influence of the shape and location of the flux diverter on the AC loss characteristics of stacked (RE)BCO tapes is investigated by use of a finite element method. Taking both the AC loss of the (RE)BCO coils and the ferromagnetic loss of the flux diverter into account, the optimal geometry of the flux diverter is obtained. It is found that when the applied current is at half the value of the critical current, the total loss of the HTS stack with the optimal flux diverter is only 18% of the original loss of the HTS stack without the flux diverter. Besides, the effect of the flux diverter on the critical current of the (RE)BCO stack is investigated.

The effect of phosphorylation on arrestin-rhodopsin interaction in the squid visual system.

PubMed

Robinson, Kelly A; Ou, Wei-Lin; Guan, Xinyu; Sugamori, Kim S; Bandyopadhyay, Abhishek; Ernst, Oliver P; Mitchell, Jane

2015-12-01

Invertebrate visual opsins are G protein-coupled receptors coupled to retinoid chromophores that isomerize reversibly between inactive rhodopsin and active metarhodopsin upon absorption of photons of light. The squid visual system has an arrestin protein that binds to metarhodopsin to block signaling to Gq and activation of phospholipase C. Squid rhodopsin kinase (SQRK) can phosphorylate both metarhodopsin and arrestin, a dual role that is unique among the G protein-coupled receptor kinases. The sites and role of arrestin phosphorylation by SQRK were investigated here using recombinant proteins. Arrestin was phosphorylated on serine 392 and serine 397 in the C-terminus. Unphosphorylated arrestin bound to metarhodopsin and phosphorylated metarhodopsin with similar high affinities (Kd 33 and 21 nM respectively), while phosphorylation of arrestin reduced the affinity 3- to 5-fold (Kd 104 nM). Phosphorylation of metarhodopsin slightly increased the dissociation of arrestin observed during a 1 hour incubation. Together these studies suggest a unique role for SQRK in phosphorylating both receptor and arrestin and inhibiting the binding of these two proteins in the squid visual system. Invertebrate visual systems are inactivated by arrestin binding to metarhodopsin that does not require receptor phosphorylation. Here we show that squid rhodopsin kinase phosphorylates arrestin on two serines (S392,S397) in the C-terminus and phosphorylation decreases the affinity of arrestin for squid metarhodopsin. Metarhodopsin phosphorylation has very little effect on arrestin binding but does increase arrestin dissociation. © 2015 International Society for Neurochemistry.

Partial characterization of an effluent produced by cooking of Jumbo squid (Dosidicus gigas) mantle muscle.

PubMed

Rosas-Romero, Zaidy G; Ramirez-Suarez, Juan C; Pacheco-Aguilar, Ramón; Lugo-Sánchez, Maria E; Carvallo-Ruiz, Gisela; García-Sánchez, Guillermina

2010-01-01

Jumbo squid (Dosidicus gigas) mantle muscle was cooked simulating industrial procedures (95 degrees C x 25 min, 1.2:5 muscle:water ratio). The effluent produced was analyzed for chemical and biochemical oxygen demands (COD and BOD(5), respectively), proximate analysis, flavor-related compounds (free amino acids, nucleotides and carbohydrates) and SDS-PAGE. The COD and BOD(5) exhibited variation among samplings (N=3) (27.4-118.5 g O(2)/L for COD and 11.3-26.7 g O(2)/L for BOD(5)). The effluent consisted of 1% total solids, 75% of which represented crude protein. Sixty percent of the total free amino acid content, which imparts flavor in squid species, corresponded to glutamic acid, serine, glycine, arginine, alanine, leucine and lysine. The nucleotide concentration followed this order, Hx>ADP>AMP>ATP>IMP>HxR. The variation observed in the present work was probably due to physiological maturity differences among the squid specimens (i.e., juvenile versus mature). Solids present in squid cooking effluent could be recovered and potentially used as flavor ingredients in squid-analog production by the food industry.

Sensitive spin detection using an on-chip SQUID-waveguide resonator

NASA Astrophysics Data System (ADS)

Yue, G.; Chen, L.; Barreda, J.; Bevara, V.; Hu, L.; Wu, L.; Wang, Z.; Andrei, P.; Bertaina, S.; Chiorescu, I.

2017-11-01

Precise detection of spin resonance is of paramount importance to achieve coherent spin control in quantum computing. We present a setup for spin resonance measurements, which uses a dc-SQUID flux detector coupled to an antenna from a coplanar waveguide. The SQUID and the waveguide are fabricated from a 20 nm Nb thin film, allowing high magnetic field operation with the field applied parallel to the chip. We observe a resonance signal between the first and third excited states of Gd spins S = 7/2 in a CaWO4 crystal, relevant for state control in multi-level systems.

Expression of squid iridescence depends on environmental luminance and peripheral ganglion control.

PubMed

Gonzalez-Bellido, P T; Wardill, T J; Buresch, K C; Ulmer, K M; Hanlon, R T

2014-03-15

Squid display impressive changes in body coloration that are afforded by two types of dynamic skin elements: structural iridophores (which produce iridescence) and pigmented chromatophores. Both color elements are neurally controlled, but nothing is known about the iridescence circuit, or the environmental cues, that elicit iridescence expression. To tackle this knowledge gap, we performed denervation, electrical stimulation and behavioral experiments using the long-fin squid, Doryteuthis pealeii. We show that while the pigmentary and iridescence circuits originate in the brain, they are wired differently in the periphery: (1) the iridescence signals are routed through a peripheral center called the stellate ganglion and (2) the iridescence motor neurons likely originate within this ganglion (as revealed by nerve fluorescence dye fills). Cutting the inputs to the stellate ganglion that descend from the brain shifts highly reflective iridophores into a transparent state. Taken together, these findings suggest that although brain commands are necessary for expression of iridescence, integration with peripheral information in the stellate ganglion could modulate the final output. We also demonstrate that squid change their iridescence brightness in response to environmental luminance; such changes are robust but slow (minutes to hours). The squid's ability to alter its iridescence levels may improve camouflage under different lighting intensities.

77 FR 22678 - Fisheries of the Northeastern United States; Atlantic Mackerel, Squid, and Butterfish Fisheries...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-17

.... 110707371-2136-02] RIN 0648- XB145 Fisheries of the Northeastern United States; Atlantic Mackerel, Squid, and Butterfish Fisheries; Closure of the Trimester 1 Longfin Squid Fishery AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric Administration (NOAA), Commerce. ACTION...

Development of Kilo-Pixel Arrays of Transition-Edge Sensors for X-Ray Spectroscopy

NASA Technical Reports Server (NTRS)

Adams, J. S.; Bandler, S. R.; Busch, S. E.; Chervenak, J. A.; Chiao, M. P.; Eckart, M. E.; Ewin, A. J.; Finkbeiner, F. M.; Kelley, R. L.; Kelly, D. P.;

Vestigial phragmocone in the gladius points to a deepwater origin of squid (Mollusca: Cephalopoda)

NASA Astrophysics Data System (ADS)

Arkhipkin, Alexander I.; Bizikov, Vyacheslav A.; Fuchs, Dirk

2012-03-01

The microstructure of the gladius cone was investigated in six species of nektonic squid: shallow-water Loligo gahi (Loliginidae), pelagic eurybathic Illex argentinus, Todarodes pacificus, Dosidicus gigas (Ommastrephidae), and deepwater Onykia ingens (Onychoteuthidae) and Gonatus antarcticus (Gonatidae) using state-of-the-art microscopy. Apart from L. gahi, all other species had septa-like layers in the gladius cone, which for the first time were investigated in detail and compared with those in extinct Cretaceous belemnites Hibolithes sp. and Pachyteuthis sp., and spirulid Cyrtobelus sp. It was found that the organic layers of the gladius cone in recent squid can be homologized with the organic components of the shell in fossil phragmocone-bearing coleoids. The septa-like layers in modern gladius cones therefore represent a vestigial phragmocone composed of organic septal rudiments of the ancestral phragmocone that has lost the siphuncle and gas-filled chambers. The well-developed rostrum in onychoteuthids and small rostrum of the gladius in ommastrephids and gonatids can be seen as homologous with the belemnoid rostrum, which may indicate a close phylogenetic relationship between belemnites and at least some squid. Possible evolutionary pathways of the reduction of the functional phragmocone in squid ancestors are discussed. Several features such as the loss of shell calcification, deep water speciation, and the structure of the equilibrium organ point to a deep-water origin of squids.

One Period of Exploration with the Squid.

ERIC Educational Resources Information Center

Bradley, James V.; Ng, Andrew

1997-01-01

Presents a lab that can be offered after students have learned the basic anatomy and physiology of the various phyla, the primary objective of which is to explore and apply their acquired knowledge to a new situation. Involves exploring the anatomy and life-style of the squid. (JRH)

Operating characteristic analysis of a 400 mH class HTS DC reactor in connection with a laboratory scale LCC type HVDC system

NASA Astrophysics Data System (ADS)

Kim, Sung-Kyu; Kim, Kwangmin; Park, Minwon; Yu, In-Keun; Lee, Sangjin

2015-11-01

High temperature superconducting (HTS) devices are being developed due to their advantages. Most line commutated converter based high voltage direct current (HVDC) transmission systems for long-distance transmission require large inductance of DC reactor; however, generally, copper-based reactors cause a lot of electrical losses during the system operation. This is driving researchers to develop a new type of DC reactor using HTS wire. The authors have developed a 400 mH class HTS DC reactor and a laboratory scale test-bed for line-commutated converter type HVDC system and applied the HTS DC reactor to the HVDC system to investigate their operating characteristics. The 400 mH class HTS DC reactor is designed using a toroid type magnet. The HVDC system is designed in the form of a mono-pole system with thyristor-based 12-pulse power converters. In this paper, the investigation results of the HTS DC reactor in connection with the HVDC system are described. The operating characteristics of the HTS DC reactor are analyzed under various operating conditions of the system. Through the results, applicability of an HTS DC reactor in an HVDC system is discussed in detail.

Theory and application of high temperature superconducting eddy current probes for nondestructive evaluation

NASA Astrophysics Data System (ADS)

Claycomb, James Ronald

1998-10-01

Several High-T c Superconducting (HTS) eddy current probes have been developed for applications in electromagnetic nondestructive evaluation (NDE) of conducting materials. The probes utilize high-T c SUperconducting Quantum Interference Device (SQUID) magnetometers to detect the fields produced by the perturbation of induced eddy currents resulting from subsurface flaws. Localized HTS shields are incorporated to selectively screen out environmental electromagnetic interference and enable movement of the instrument in the Earth's magnetic field. High permeability magnetic shields are employed to focus flux into, and thereby increase the eddy current density in the metallic test samples. NDE test results are presented, in which machined flaws in aluminum alloy are detected by probes of different design. A novel current injection technique performing NDE of wires using SQUIDs is also discussed. The HTS and high permeability shields are designed based on analytical and numerical finite element method (FEM) calculations presented here. Superconducting and high permeability magnetic shields are modeled in uniform noise fields and in the presence of dipole fields characteristic of flaw signals. Several shield designs are characterized in terms of (1) their ability to screen out uniform background noise fields; (2) the resultant improvement in signal-to-noise ratio and (3) the extent to which dipole source fields are distorted. An analysis of eddy current induction is then presented for low frequency SQUID NDE. Analytical expressions are developed for the induced eddy currents and resulting magnetic fields produced by excitation sources above conducting plates of varying thickness. The expressions derived here are used to model the SQUID's response to material thinning. An analytical defect model is also developed, taking into account the attenuation of the defect field through the conducting material, as well as the current flow around the edges of the flaw. Time harmonic

Fabrication and Performance of Large Format Transition Edge Sensor Microcalorimeter Arrays

NASA Technical Reports Server (NTRS)

Chervenak, James A.; Adams, James S.; Bandler, Simon R.; Busch, Sara E.; Eckart, M. E.; Ewin, A. E.; Finkbeiner, F. M.; Kilbourne, C. A.; Kelley, R. L.; Porst, Jan-Patrick;

77 FR 16472 - Fisheries of the Northeastern United States; Atlantic Mackerel, Squid, and Butterfish Fisheries...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-21

...NMFS is implementing final 2012 specifications and management measures for Atlantic mackerel (mackerel), and 2012-2014 specifications for Illex and longfin squid, and interim final 2012 specifications and management measures for butterfish. This is the first year that the specifications are being set for Atlantic mackerel and butterfish under the provisions of the Mid-Atlantic Fishery Management Council's (Council) Annual Catch Limit and Accountability Measure Omnibus Amendment. This action also adjusts the closure threshold for the commercial mackerel fishery to 95 percent (from 90 percent), and allows the use of jigging gear to target longfin squid if the longfin squid fishery is closed due to the butterfish mortality cap. Finally, this rule makes minor corrections in existing regulatory text to clarify the intent of the regulations. These specifications and management measures promote the utilization and conservation of the Atlantic Mackerel, Squid, and Butterfish (MSB) resource.

Design versions of HTS three-phase cables with the minimized value of AC losses

NASA Astrophysics Data System (ADS)

Altov, V. A.; Balashov, N. N.; Degtyarenko, P. N.; Ivanov, S. S.; Kopylov, S. I.; Lipa, DA; Samoilenkov, S. V.; Sytnikov, V. E.; Zheltov, V. V.

2018-03-01

Design versions of HTS three-phase cables consisting of 2G HTS tapes have been investigated by the numerical simulation method with the aim of AC losses minimization. Two design versions of cables with the coaxial and extended rectangular cross-section shape are considered – the non-sectioned and sectioned one. In the latter each cable phase consists of sections connected in parallel. The optimal dimensions of sections and order of their alteration are chosen by appropriate calculations. The model used takes into account the current distribution between the sections and its non-uniformity within each single HTS tape as well. The following characteristics are varied: design version, dimension, positioning of extra copper layer in a cable, design of HTS tapes themselves and their mutual position. The dependence of AC losses on the latter two characteristics is considered in details, and the examples of cable designs optimized by the total set of characteristics for the medium class of voltages (10 – 60 kV) are given. At the critical current JC=5.1 кA per phase and current amplitudes lower than 0.85JC, the level of total AC losses does not exceed the natural cryostat heat losses.

Rapid Associative Learning and Stable Long-Term Memory in the Squid Euprymna scolopes.

PubMed

Zepeda, Emily A; Veline, Robert J; Crook, Robyn J

2017-06-01

Learning and memory in cephalopod molluscs have received intensive study because of cephalopods' complex behavioral repertoire and relatively accessible nervous systems. While most of this research has been conducted using octopus and cuttlefish species, there has been relatively little work on squid. Euprymna scolopes Berry, 1913, a sepiolid squid, is a promising model for further exploration of cephalopod cognition. These small squid have been studied in detail for their symbiotic relationship with bioluminescent bacteria, and their short generation time and successful captive breeding through multiple generations make them appealing models for neurobiological research. However, little is known about their behavior or cognitive ability. Using the well-established "prawn-in-the-tube" assay of learning and memory, we show that within a single 10-min trial E. scolopes learns to inhibit its predatory behavior, and after three trials it can retain this memory for at least 12 d. Rapid learning and very long-term retention were apparent under two different training schedules. To our knowledge, this study is the first demonstration of learning and memory in this species as well as the first demonstration of associative learning in any squid.

Partial Discharge Characteristics in Composite Insulation Systems with PPLP for HTS Cable

NASA Astrophysics Data System (ADS)

Kikuchi, Y.; Yamashita, K.; Kumada, A.; Hidaka, K.; Tatamidani, K.; Masuda, T.

2014-05-01

The electrical insulation system of high-temperature superconducting (HTS) cable consists of liquid nitrogen (N2(l)) and polypropylene laminated paper (PPLP). Partial discharge (PD) may occur in butt gaps of the insulation layers and its characteristics imply the insulation performance of HTS cables. N2(l) cooling system is installed in the power system and N2(l) will flow through the cables during the system operation. Filling the HTS cable with N2(l) in order to perform pre-shipment inspection is time-consuming and costly for cable manufacturers. Therefore, they are trying to find a cost effective method for pre-shipment inspections. One alternative is to use high pressure gaseous nitrogen (N2(g)) instead of N2(l). This article investigates PD characteristics such as PD inception electric field (PDIE) and PD extinction electric field (PDEE) in butt gaps of HTS cables in 0.1 to 0.3 MPa and 0.1 MPa to 1.0 MPa N2(g) environments. For assessing the surface/volume effects, PD characteristics are measured with changing the size of butt gaps. It turns out that PDIE and PDEE in N2(g) are linearly correlated with those in N2(l) at any gas pressure in our testing, and PDIE in 1.0 MPa N2(g) is almost 30% of that in 0.2 MPa It suggests that PD characteristics in N2(l) can be extrapolated from those in N2(g).

Characterization System of Multi-pixel Array TES Microcalorimeter

NASA Astrophysics Data System (ADS)

Yoshimoto, Shota; Maehata, Keisuke; Mitsuda, Kazuhisa; Yamanaka, Yoshihiro; Sakai, Kazuhiro; Nagayoshi, Kenichiro; Yamamoto, Ryo; Hayashi, Tasuku; Muramatsu, Haruka

We have constructed characterization system for 64-pixel array transition-edge sensor (TES) microcalorimeter using a 3He-4He dilution refrigerator (DR) with the cooling power of 60 µW at a temperature of 100 mK. A stick equipped with 384 of Manganin wires was inserted into the refrigerator to perform characteristic measurements of 64-pixel array TES microcalorimeter and superconducting quantum interference device (SQUID) array amplifiers. The stick and Manganin wires were thermally anchored at temperatures of 4 and 1 K with sufficient thermal contact. The cold end of the Manganin wires were thermally anchored and connected to CuNi clad NbTi wires at 0.7 K anchor. Then CuNi clad NbTi wires were wired to connectors placed on the holder mounted on the cold stage attached to the base plate of the mixing chamber. The heat flow to the cold stage through the installed wires was estimated to be 0.15 µW. In the operation test the characterization system maintained temperature below 100 mK.

Cross-linking Chemistry of Squid Beak*

PubMed Central

Miserez, Ali; Rubin, Daniel; Waite, J. Herbert

2010-01-01

In stark contrast to most aggressive predators, Dosidicus gigas (jumbo squids) do not use minerals in their powerful mouthparts known as beaks. Their beaks instead consist of a highly sclerotized chitinous composite with incremental hydration from the tip to the base. We previously reported l-3,4-dihydroxyphenylalanine (dopa)-histidine (dopa-His) as an important covalent cross-link providing mechanical strengthening to the beak material. Here, we present a more complete characterization of the sclerotization chemistry and describe additional cross-links from D. gigas beak. All cross-links presented in this report share common building blocks, a family of di-, tri-, and tetra-histidine-catecholic adducts, that were separated by affinity chromatography and high performance liquid chromatography (HPLC) and identified by tandem mass spectroscopy and proton nuclear magnetic resonance (1H NMR). The data provide additional insights into the unusually high cross-link density found in mature beaks. Furthermore, we propose both a low molecular weight catechol, and peptidyl-dopa, to be sclerotization agents of squid beak. This appears to represent a new strategy for forming hard tissue in animals. The interplay between covalent cross-linking and dehydration on the graded properties of the beaks is discussed. PMID:20870720

Cross-linking chemistry of squid beak.

PubMed

Miserez, Ali; Rubin, Daniel; Waite, J Herbert

2010-12-03

In stark contrast to most aggressive predators, Dosidicus gigas (jumbo squids) do not use minerals in their powerful mouthparts known as beaks. Their beaks instead consist of a highly sclerotized chitinous composite with incremental hydration from the tip to the base. We previously reported l-3,4-dihydroxyphenylalanine (dopa)-histidine (dopa-His) as an important covalent cross-link providing mechanical strengthening to the beak material. Here, we present a more complete characterization of the sclerotization chemistry and describe additional cross-links from D. gigas beak. All cross-links presented in this report share common building blocks, a family of di-, tri-, and tetra-histidine-catecholic adducts, that were separated by affinity chromatography and high performance liquid chromatography (HPLC) and identified by tandem mass spectroscopy and proton nuclear magnetic resonance ((1)H NMR). The data provide additional insights into the unusually high cross-link density found in mature beaks. Furthermore, we propose both a low molecular weight catechol, and peptidyl-dopa, to be sclerotization agents of squid beak. This appears to represent a new strategy for forming hard tissue in animals. The interplay between covalent cross-linking and dehydration on the graded properties of the beaks is discussed.

Fishery biology of jumbo flying squid Dosidicus gigas off Costa Rica Dome

NASA Astrophysics Data System (ADS)

Chen, Xinjun; Li, Jianghua; Liu, Bilin; Li, Gang; Lu, Huajie

2014-06-01

The jumbo flying squid ( Dosidicus gigas) population was surveyed with the help of Chinese squid jigging vessels off the Costa Rica Dome (4°-11°N, 90°-100°W) in 2009 and 2010. The daily catch of D. gigas in the two survey cruises ranged from 0 to 5.5 t and was mostly obtained from the areas bounded by 6°-9°N and 91°-94°W and by 6°30'-7°30'N and 96°-97°W. The sea surface temperature in the areas yielding the most catch ranged from 27.5 to 29°C. The sex ratio of the total catch was 3.75:1 (female: male). The mantle length of the squid ranged from 211 to 355 mm (male) and from 204 to 429 mm (female) with an average of 297.9 and 306.7 mm, respectively. In the relationship of the mantle length (mm) and body weight (g) of the squid, there was no significant difference between sexes. The female and male were at a similar maturity, and most individuals are maturing or have matured with a few females being spent. The size (mantle length) and age at the first sexual maturity were 297 mm and 195 d in females, and less than 211 mm and 130 d in males, respectively. Most of the sampled stomachs (70.6%) had no food remains. The major preys of the squids were fish, cephalopods and crustaceans, with the most abundant Myctophum orientale and D. gigas. The preys in more than 65% of the non-empty sampled stomachs evidenced the cannibalism of D. gigas. The results improved current understanding of the fishery biology of D. gigas off the Costa Rica Dome, which may facilitate the assessment and management of relative fishery resources.

Nuisance Compounds, PAINS Filters, and Dark Chemical Matter in the GSK HTS Collection.

PubMed

Chakravorty, Subhas J; Chan, James; Greenwood, Marie Nicole; Popa-Burke, Ioana; Remlinger, Katja S; Pickett, Stephen D; Green, Darren V S; Fillmore, Martin C; Dean, Tony W; Luengo, Juan I; Macarrón, Ricardo

2018-07-01

High-throughput screening (HTS) hits include compounds with undesirable properties. Many filters have been described to identify such hits. Notably, pan-assay interference compounds (PAINS) has been adopted by the community as the standard term to refer to such filters, and very useful guidelines have been adopted by the American Chemical Society (ACS) and subsequently triggered a healthy scientific debate about the pitfalls of draconian use of filters. Using an inhibitory frequency index, we have analyzed in detail the promiscuity profile of the whole GlaxoSmithKline (GSK) HTS collection comprising more than 2 million unique compounds that have been tested in hundreds of screening assays. We provide a comprehensive analysis of many previously published filters and newly described classes of nuisance structures that may serve as a useful source of empirical information to guide the design or growth of HTS collections and hit triaging strategies.

The mechanics of locomotion in the squid Loligo pealei: locomotory function and unsteady hydrodynamics of the jet and intramantle pressure.

PubMed

Anderson, E J; DeMont, M E

2000-09-01

High-speed, high-resolution digital video recordings of swimming squid (Loligo pealei) were acquired. These recordings were used to determine very accurate swimming kinematics, body deformations and mantle cavity volume. The time-varying squid profile was digitized automatically from the acquired swimming sequences. Mantle cavity volume flow rates were determined under the assumption of axisymmetry and the condition of incompressibility. The data were then used to calculate jet velocity, jet thrust and intramantle pressure, including unsteady effects. Because of the accurate measurements of volume flow rate, the standard use of estimated discharge coefficients was avoided. Equations for jet and whole-cycle propulsive efficiency were developed, including a general equation incorporating unsteady effects. Squid were observed to eject up to 94 % of their intramantle working fluid at relatively high swimming speeds. As a result, the standard use of the so-called large-reservoir approximation in the determination of intramantle pressure by the Bernoulli equation leads to significant errors in calculating intramantle pressure from jet velocity and vice versa. The failure of this approximation in squid locomotion also implies that pressure variation throughout the mantle cannot be ignored. In addition, the unsteady terms of the Bernoulli equation and the momentum equation proved to be significant to the determination of intramantle pressure and jet thrust. Equations of propulsive efficiency derived for squid did not resemble Froude efficiency. Instead, they resembled the equation of rocket motor propulsive efficiency. The Froude equation was found to underestimate the propulsive efficiency of the jet period of the squid locomotory cycle and to overestimate whole-cycle propulsive efficiency when compared with efficiencies calculated from equations derived with the squid locomotory apparatus in mind. The equations for squid propulsive efficiency reveal that the refill

A miniaturized HTS microwave receiver front-end subsystem for radar and communication applications

NASA Astrophysics Data System (ADS)

Bian, Yongbo; Guo, Jin; Gao, Changzheng; Li, Chunguang; Li, Hong; Wang, Jia; Cui, Bin; He, Xiaofeng; Li, Chao; Li, Na; Li, Guoqiang; Zhang, Qiang; Zhang, Xueqiang; Meng, Jibao; He, Yusheng

2010-08-01

This paper presents a miniaturized high performance high temperature superconducting (HTS) microwave receiver front-end subsystem, which uses a mini stirling cryocooler to cool a high selective HTS filter and a low noise amplifier (LNA). The HTS filter was miniaturized by using specially designed compact resonators and fabricating with double-sided YBCO films on LAO substrate which has a relatively high permittivity. The LNA was specially designed to work at cryogenic temperature with noise figure of 0.27 dB at 71 K. The mini cryocooler, which is widely used in infrared detectors, has a smaller size (60 mm × 80 mm × 100 mm) and a lighter weight (340 g) than the stirling cryocoolers commonly used in other HTS filter subsystem. The whole front-end subsystem, including a HTS filter, a LNA, a cryocooler and the vacuum chamber, has a size of only φ120 mm × 175 mm and a weight of only 3.3 kg. The microwave devices inside the subsystem are working at 71.8 K with a consumed cooling power of 0.325 W. The center frequency of this subsystem is 925.2 MHz and the bandwidth is 2.7 MHz (which is a fractional bandwidth of 0.2%), with the gain of 19.75 dB at center frequency and the return loss better than -18.11 dB in the pass band. The stop band rejection is more than 60 dB and the skirt slope is exceeding 120 dB MHz -1. The noise figure of this subsystem is less than 0.8 dB. This front-end subsystem can be used in radars and communication systems conveniently due to it’s compact size and light weight.

Squid 'ear bones' (statoliths) from the Jurassic succession of South-west England

NASA Astrophysics Data System (ADS)

Hart, Malcolm; Page, Kevin; Price, Gregory; Smart, Christopher

2015-04-01

Squid 'ear bones' - or statoliths - are a part of the balancing organs of modern and probably most fossil squids. Over the course of the last 10 years fossil statoliths have been discovered in the Jurassic sediments of the Wessex Basin (South-west England). They are probably all related to teuthids, such as Belemnotheutis antiquus Pearce, of Callovian-Oxfordian age. Thus far, we have identified four possible 'species' of statolith that are in the process of being formally described, named and their potential relationships determined. The sediments from which these statoliths have been recorded also contain squid hooklets (onycites), otoliths (fish 'ear bones') and other microfossils (including foraminifera). All are, therefore, of marine origin. In the case of the Christian Malford and Ashton Keynes lagerstätte (of late Callovian age), the statoliths are associated with exceptional, soft-bodied preservation of squid and it may be possible to determine the parent animal of the recorded statoliths. A number of museum collections (Natural History Museum [London], Natural History Museum [Paris], Senckenberg [Frankfurt], Smithsonian Institution [Washington], etc.) are being investigated in order to trace the possible host animals for all of the recorded statoliths. Despite many thousands of samples of Cretaceous sediments being investigated for foraminifera over the past 40+ years, no statoliths have been recorded and none are known from the literature.

Deep-sea in situ observations of gonatid squid and their prey reveal high occurrence of cannibalism

NASA Astrophysics Data System (ADS)

Hoving, H. J. T.; Robison, B. H.

2016-10-01

In situ observations are rarely applied in food web studies of deep-sea organisms. Using deep-sea observations obtained by remotely operated vehicles in the Monterey Submarine Canyon, we examined the prey choices of more than 100 individual squids of the genus Gonatus. Off the California coast, these squids are abundant, semelparous (one reproductive cycle) oceanic predators but their diet has remained virtually unknown. Gonatus onyx and Gonatus berryi were observed to feed on mesopelagic fishes (in particular the myctophid Stenobrachius leucopsarus) as often as on squids but inter-specific differences in feeding were apparent. Gonatids were the most common squid prey and while cannibalism occurred in both species it was particularly high in Gonatus onyx (42% of all prey items). Typically, the size of prey was similar to the size of the predator but the squids were also seen to take much larger prey. Postjuvenile gonatids are opportunistic predators that consume nektonic members of the meso-and bathypelagic communities, including their own species. Such voracious feeding is likely necessary to support the high energetic demands associated with the single reproductive event; and for females the long brooding period during which they must depend on stored resources.

Extreme plasticity in life-history strategy allows a migratory predator (jumbo squid) to cope with a changing climate.

PubMed

Hoving, Henk-Jan T; Gilly, William F; Markaida, Unai; Benoit-Bird, Kelly J; -Brown, Zachary W; Daniel, Patrick; Field, John C; Parassenti, Liz; Liu, Bilin; Campos, Bernardita

2013-07-01

Dosidicus gigas (jumbo or Humboldt squid) is a semelparous, major predator of the eastern Pacific that is ecologically and commercially important. In the Gulf of California, these animals mature at large size (>55 cm mantle length) in 1-1.5 years and have supported a major commercial fishery in the Guaymas Basin during the last 20 years. An El Niño event in 2009-2010, was accompanied by a collapse of this fishery, and squid in the region showed major changes in the distribution and life-history strategy. Large squid abandoned seasonal coastal-shelf habitats in 2010 and instead were found in the Salsipuedes Basin to the north, an area buffered from the effects of El Niño by tidal upwelling and a well-mixed water column. The commercial fishery also relocated to this region. Although large squid were not found in the Guaymas Basin from 2010 to 2012, small squid were abundant and matured at an unusually small mantle-length (<30 cm) and young age (approximately 6 months). Juvenile squid thus appeared to respond to El Niño with an alternative life-history trajectory in which gigantism and high fecundity in normally productive coastal-shelf habitats were traded for accelerated reproduction at small size in an offshore environment. Both small and large mature squid, were present in the Salsipuedes Basin during 2011, indicating that both life- history strategies can coexist. Hydro-acoustic data, reveal that squid biomass in this study area nearly doubled between 2010 and 2011, primarily due to a large increase in small squid that were not susceptible to the fishery. Such a climate-driven switch in size-at-maturity may allow D. gigas to rapidly adapt to and cope with El Niño. This ability is likely to be an important factor in conjunction with longerterm climate-change and the potential ecological impacts of this invasive predator on marine ecosystems. © 2013 Blackwell Publishing Ltd.

High-T(sub c) Superconductor-Normal-Superconductor Junctions with Polyimide-Passivated Ambient Temperature Edge Formation

NASA Technical Reports Server (NTRS)

Barner, J. B.; Kleinsasser, A. W.; Hunt, B. D.

1996-01-01

The ability to controllably fabricate High-Temperature Superconductor (HTS) S-Normal-S (SNS) Josephson Juntions (JJ's) enhances the possibilities fro many applications, including digital circuits, SQUID's, and mixers. A wide variety of approaches to fabricating SNS-like junctions has been tried and analyzed in terms of proximity effect behavior.

77 FR 74159 - Fisheries of the Northeastern United States; Atlantic Mackerel, Squid, and Butterfish Fisheries...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-13

.... SUMMARY: NMFS proposes changing the butterfish mortality cap on the longfin squid fishery from a catch cap to a discard cap in Framework Adjustment 7 to the Atlantic Mackerel, Squid, and Butterfish Fishery Management Plan,. This action also proposes reducing the butterfish mortality cap for the 2013 fishing year...

Front-end multiplexing—applied to SQUID multiplexing: Athena X-IFU and QUBIC experiments

NASA Astrophysics Data System (ADS)

Prele, D.

2015-08-01

As we have seen for digital camera market and a sensor resolution increasing to "megapixels", all the scientific and high-tech imagers (whatever the wave length - from radio to X-ray range) tends also to always increases the pixels number. So the constraints on front-end signals transmission increase too. An almost unavoidable solution to simplify integration of large arrays of pixels is front-end multiplexing. Moreover, "simple" and "efficient" techniques allow integration of read-out multiplexers in the focal plane itself. For instance, CCD (Charge Coupled Device) technology has boost number of pixels in digital camera. Indeed, this is exactly a planar technology which integrates both the sensors and a front-end multiplexed readout. In this context, front-end multiplexing techniques will be discussed for a better understanding of their advantages and their limits. Finally, the cases of astronomical instruments in the millimeter and in the X-ray ranges using SQUID (Superconducting QUantum Interference Device) will be described.

Comprehensive model of Jumbo squid Dosidicus gigas trophic ecology in the Northern Humboldt current system.

PubMed

Alegre, Ana; Ménard, Frédéric; Tafur, Ricardo; Espinoza, Pepe; Argüelles, Juan; Maehara, Víctor; Flores, Oswaldo; Simier, Monique; Bertrand, Arnaud

2014-01-01

The jumbo squid Dosidicus gigas plays an important role in marine food webs both as predator and prey. We investigated the ontogenetic and spatiotemporal variability of the diet composition of jumbo squid in the northern Humboldt Current system. For that purpose we applied several statistical methods to an extensive dataset of 3,618 jumbo squid non empty stomachs collected off Peru from 2004 to 2011. A total of 55 prey taxa was identified that we aggregated into eleven groups. Our results evidenced a large variability in prey composition as already observed in other systems. However, our data do not support the hypothesis that jumbo squids select the most abundant or energetic taxon in a prey assemblage, neglecting the other available prey. Indeed, multinomial model predictions showed that stomach fullness increased with the number of prey taxa, while most stomachs with low contents contained one or two prey taxa only. Our results therefore question the common hypothesis that predators seek locally dense aggregations of monospecific prey. In addition D. gigas consumes very few anchovy Engraulis ringens in Peru, whereas a tremendous biomass of anchovy is potentially available. It seems that D. gigas cannot reach the oxygen unsaturated waters very close to the coast, where the bulk of anchovy occurs. Indeed, even if jumbo squid can forage in hypoxic deep waters during the day, surface normoxic waters are then required to recover its maintenance respiration (or energy?). Oxygen concentration could thus limit the co-occurrence of both species and then preclude predator-prey interactions. Finally we propose a conceptual model illustrating the opportunistic foraging behaviour of jumbo squid impacted by ontogenetic migration and potentially constrained by oxygen saturation in surface waters.

The squid-Vibrio symbioses: from demes to genes.

PubMed

Kimbell, Jennifer R; McFall-Ngai, Margaret J

2003-04-01

The monospecific light organ association between the Hawaiian sepiolid squid Euprymna scolopes and the marine luminous bacterium Vibrio fischeri has been used as a model for the study of the most common type of coevolved animal-bacterial interaction; i.e., the association of Gram-negative bacteria with the extracellular apical surfaces of polarized epithelia. Analysis of the squid-vibrio symbiosis has ranged from characterizations of the harvesting mechanisms by which the host ensures colonization by the appropriate symbiont to identification of bacteria-induced changes in host gene expression that accompany the establishment and maintenance of the relationship. Studies of this model have been enhanced by extensive collaboration with microbiologists, who are able to manipulate the genetics of the bacterial symbiont. The results of our studies have indicated that initiation and persistence of the association requires a complex, reciprocal molecular dialogue between these two phylogenetically distant partners.

Dispersive Readout of a Superconducting Flux Qubit Using a Microstrip SQUID Amplifier

NASA Astrophysics Data System (ADS)

Johnson, J. E.; Hoskinson, E. M.; Macklin, C.; Siddiqi, I.; Clarke, John

2011-03-01

Dispersive techniques for the readout of superconducting qubits offer the possibility of high repetition-rate, quantum non-demolition measurement by avoiding dissipation close to the qubit. To achieve dispersive readout, we couple our three-junction aluminum flux qubit inductively to a 1-2 GHz non-linear oscillator formed by a capacitively shunted DC SQUID. The frequency of this resonator is modulated by the state of the qubit via the flux-dependent inductance of the SQUID. Readout is performed by probing the resonator in the linear (weak drive) regime with a microwave tone and monitoring the phase of the reflected signal. A microstrip SQUID amplifier (MSA) is used to increase the sensitivity of the measurement over that of a HEMT (high electron mobility transistor) amplifier. We report measurements of the performance of our amplification chain. Increased fidelity and reduced measurement backaction resulting from the implementation of the MSA will also be discussed. This work was funded in part by the U.S. Government and by BBN Technologies.

Cycle Design of Reverse Brayton Cryocooler for HTS Cable Cooling Using Exergy Analysis

NASA Astrophysics Data System (ADS)

Gupta, Sudeep Kumar; Ghosh, Parthasarathi

2017-02-01

The reliability and price of cryogenic refrigeration play an important role in the successful commercialization of High Temperature Superconducting (HTS) cables. For cooling HTS cable, sub-cooled liquid nitrogen (LN2) circulation system is used. One of the options to maintain LN2 in its sub-cooled state is by providing refrigeration with the help of Reverse Brayton Cryo-cooler (RBC). The refrigeration requirement is 10 kW for continuously sub-cooling LN2 from 72 K to 65 K for cooling 1 km length of HTS cable [1]. In this paper, a parametric evaluation of RBC for sub-cooling LN2 has been performed using helium as a process fluid. Exergy approach has been adopted for this analysis. A commercial process simulator, Aspen HYSYS® V8.6 has been used for this purpose. The critical components have been identified and their exergy destruction and exergy efficiency have been obtained for a given heat load condition.

Apparatus and method for detecting a magnetic anomaly contiguous to remote location by SQUID gradiometer and magnetometer systems

DOEpatents

Overton, W.C. Jr.; Steyert, W.A. Jr.

1981-05-22

A superconducting quantum interference device (SQUID) magnetic detection apparatus detects magnetic fields, signals, and anomalies at remote locations. Two remotely rotatable SQUID gradiometers may be housed in a cryogenic environment to search for and locate unambiguously magnetic anomalies. The SQUID magnetic detection apparatus can be used to determine the azimuth of a hydrofracture by first flooding the hydrofracture with a ferrofluid to create an artificial magnetic anomaly therein.

Heat loss analysis-based design of a 12 MW wind power generator module having an HTS flux pump exciter

NASA Astrophysics Data System (ADS)

Sung, Hae-Jin; Go, Byeong-Soo; Jiang, Zhenan; Park, Minwon; Yu, In-Keun

2016-11-01

The development of an effective high-temperature superconducting (HTS) generator is currently a research focus; however, the reduction of heat loss of a large-scale HTS generator is a challenge. This study deals with a heat loss analysis-based design of a 12 MW wind power generator module having an HTS flux pump exciter. The generator module consists of an HTS rotor of the generator and an HTS flux pump exciter. The specifications of the module were described, and the detailed configuration of the module was illustrated. For the heat loss analysis of the module, the excitation loss of the flux pump exciter, eddy current loss of all of the structures in the module, radiation loss, and conduction loss of an HTS coil supporter were assessed using a 3D finite elements method program. In the case of the conduction loss, different types of the supporters were compared to find out the supporter of the lowest conduction loss in the module. The heat loss analysis results of the module were reflected in the design of the generator module and discussed in detail. The results will be applied to the design of large-scale superconducting generators for wind turbines including a cooling system.

Array-scale performance of TES X-ray Calorimeters Suitable for Constellation-X

NASA Technical Reports Server (NTRS)

Kilbourne, C. A.; Bandler, S. R.; Brown, A. D.; Chervenak, J. A.; Eckart, M. E.; Finkbeiner, F. M.; Iyomoto, N.; Kelley, R. L.; Porter, F. S.; Smith, S. J.;

[Determination of proximal chemical composition of squid (dosidicus gigas) and development of gel products].

PubMed

Abugoch, L; Guarda, A; Pérez, L M; Paredes, M P

1999-06-01

The good nutritional properties of meat from big squid (Dosidicus gigas) living on the Chilean coast, was determined through its proximal composition 70 cal/100 g fresh meat; 82.23 +/- 0.98% moisture; 15.32 +/- 0.93% protein; 1.31 +/- 0.12% ashes; 0.87 +/- 0.18% fat and 0.27% NNE (non-nitrogen extract). The big squid meat was used to develop a gel product which contained NaCl and TPP. It was necessary to use additives for gel preparation, such as carragenin or alginate or egg albumin, due to the lack of gelation properties of squid meat. Formulations containing egg albumin showed the highest gel force measured by penetration as compared to those that contained carragenin or alginate.

Potential use of stable isotope and fatty acid analyses for traceability of geographic origins of jumbo squid (Dosidicus gigas).

PubMed

Gong, Yi; Li, Yunkai; Chen, Xinjun; Chen, Ling

2018-04-15

Squid is an important seafood resource for Asian and European countries. With the continuous development of processed squid products, an effective traceability system has become increasingly prominent. Here, we attempt to trace the fishery products of the main target species, jumbo squid (Dosidicus gigas), by using biochemical tracers. Carbon and nitrogen isotope ratios (δ 13 C and δ 15 N values) and fatty acid profiles were identified in squid from three harvest locations in the eastern Pacific Ocean by isotope ratio mass spectrometry and gas chromatography/mass spectrometry, respectively. Comparative analysis was used to evaluate the geographic variations in tracers and to identify the suitable discriminatory variables among origins. Significant spatial variations were found in isotopic values and fatty acid profiles in squid muscle tissues, possibly because of different food availability and/or oceanographic conditions that each group experiences at a given location. The stepwise discriminant analysis indicated that δ 15 N, C16:1n7, C17:1n7, C18:2n6, C20:1 and C20:4n6 were effective variables at differentiating origin. Combined use of stable isotope ratios and fatty acid analyses could trace geographic origins of jumbo squid. This study provides an alternative approach for improving authenticity evaluation of commercial squid products. Copyright © 2018 John Wiley & Sons, Ltd.

Development of Prototype HTS Components for Magnetic Suspension Applications

NASA Technical Reports Server (NTRS)

Haldar, P.; Hoehn, J., Jr.; Selvamanickam, V.; Farrell, R. A.; Balachandran, U.; Iyer, A. N.; Peterson, E.; Salazar, K.

1996-01-01

We have concentrated on developing prototype lengths of bismuth and thallium based silver sheathed superconductors by the powder-in-tube approach to fabricate high temperature superconducting (HTS) components for magnetic suspension applications. Long lengths of mono and multi filament tapes are presently being fabricated with critical current densities useful for maglev and many other applications. We have recently demonstrated the prototype manufacture of lengths exceeding 1 km of Bi-2223 multi filament conductor. Long lengths of thallium based multi-filament conductor have also been fabricated with practical levels of critical current density and improved field dependence behavior. Test coils and magnets have been built from these lengths and characterized over a range of temperatures and background fields to determine their performance. Work is in progress to develop, fabricate and test HTS windings that will be suitable for magnetic suspension, levitation and other electric power related applications.

Energetics of an rf SQUID Coupled to Two Thermal Reservoirs

DOE PAGES

Gardas, B.; Łuczka, J.; Ptok, A.; ...

2015-12-07

We study energetics of a Josephson tunnel junction connecting a superconducting loop pierced by an external magnetic flux (an rf SQUID) and coupled to two independent thermal reservoirs of different temperature. In the framework of the theory of quantum dissipative systems, we analyze energy currents in stationary states. The stationary energy flow can be periodically modulated by the external magnetic flux exemplifying the rf SQUID as a quantum heat interferometer. Additionally, we consider the transient regime and identify three distinct regimes: monotonic decay, damped oscillations and pulse-type behavior of energy currents. Furthermore, the first two regimes can be controlled bymore » the external magnetic flux while the last regime is robust against its variation.« less

Natural mortality estimation and rational exploitation of purpleback flying squid Sthenoteuthis oualaniensis in the southern South China Sea

NASA Astrophysics Data System (ADS)

Wang, Xuehui; Qiu, Yongsong; Zhang, Peng; Du, Feiyan

2017-07-01

Based on the biological data of purpleback flying squid ( Sthenoteuthis oualaniensis) collected by light falling-net in the southern South China Sea (SCS) during September to October 2012 and March to April 2013, growth and mortality of `Medium' and `Dwarf' forms of squid are derived using the Powell-Wetherall, ELEFAN methods and length-converted catch curves (FiSAT package). Given a lack of commercial exploitation, we assume total mortality to be due entirely to natural mortality. We estimate these squid have fast growth, with growth coefficients ( k) ranging from 1.42 to 2.39, and high natural mortality ( M), with estimates ranging from 1.61 to 2.92. To sustainably exploit these squid stocks, yield per recruitment based on growth and natural mortality was determined using the Beverton-Holt dynamic pool model. We demonstrate squid stocks could sustain high fishing mortality and low ages at first capture, with an optimal fishing mortality >3.0, with the optimal age at first capture increased to 0.4-0.6 years when fishing mortality approached optimal levels. On the basis of our analyses and estimates of stock biomass, we believe considerable potential exists to expand the squid fishery into the open SCS, relieving fishing pressure on coastal waters.

Simulation and optimization of a dc SQUID with finite capacitance

NASA Astrophysics Data System (ADS)

de Waal, V. J.; Schrijner, P.; Llurba, R.

1984-02-01

This paper deals with the calculations of the noise and the optimization of the energy resolution of a dc SQUID with finite junction capacitance. Up to now noise calculations of dc SQUIDs were performed using a model without parasitic capacitances across the Josephson junctions. As the capacitances limit the performance of the SQUID, for a good optimization one must take them into account. The model consists of two coupled nonlinear second-order differential equations. The equations are very suitable for simulation with an analog circuit. We implemented the model on a hybrid computer. The noise spectrum from the model is calculated with a fast Fourier transform. A calculation of the energy resolution for one set of parameters takes about 6 min of computer time. Detailed results of the optimization are given for products of inductance and temperature of LT=1.2 and 5 nH K. Within a range of β and β c between 1 and 2, which is optimum, the energy resolution is nearly independent of these variables. In this region the energy resolution is near the value calculated without parasitic capacitances. Results of the optimized energy resolution are given as a function of LT between 1.2 and 10 mH K.

Characterization of Kilopixel TES detector arrays for PIPER

NASA Astrophysics Data System (ADS)

Datta, Rahul; Ade, Peter; Benford, Dominic; Bennett, Charles; Chuss, David; Costen, Nicholas; Coughlin, Kevin; Dotson, Jessie; Eimer, Joseph; Fixsen, Dale; Gandilo, Natalie; Halpern, Mark; Essinger-Hileman, Thomas; Hilton, Gene; Hinshaw, Gary; Irwin, Kent; Jhabvala, Christine; Kimball, Mark; Kogut, Al; Lazear, Justin; Lowe, Luke; Manos, George; McMahon, Jeff; Miller, Timothy; Mirel, Paul; Moseley, Samuel Harvey; Pawlyk, Samuel; Rodriguez, Samelys; Sharp, Elmer; Shirron, Peter; Staguhn, Johannes G.; Sullivan, Dan; Switzer, Eric; Taraschi, Peter; Tucker, Carole; Walts, Alexander; Wollack, Edward

2018-01-01

The Primordial Inflation Polarization ExploreR (PIPER) is a balloon-borne instrument optimized to measure the polarization of the Cosmic Microwave Background (CMB) at large angular scales. It will map 85% of the sky in four frequency bands centered at 200, 270, 350, and 600 GHz to characterize dust foregrounds and constrain the tensor-to-scalar ratio, r. The sky is imaged on to 32x40 pixel arrays of time-domain multiplexed Transition-Edge Sensor (TES) bolometers operating at a bath temperature of 100 mK to achieve background-limited sensitivity. Each kilopixel array is indium-bump-bonded to a 2D superconducting quantum interference device (SQUID) time-domain multiplexer (MUX) chip and read out by warm electronics. Each pixel measures total incident power over a frequency band defined by bandpass filters in front of the array, while polarization sensitivity is provided by the upstream Variable-delay Polarization Modulators (VPMs) and analyzer grids. We present measurements of the detector parameters from the laboratory characterization of the first kilopixel science array for PIPER including transition temperature, saturation power, thermal conductivity, time constant, and noise performance. We also describe the testing of the 2D MUX chips, optimization of the integrated readout parameters, and the overall pixel yield of the array. The first PIPER science flight is planned for June 2018 from Palestine, Texas.

HTS-Net: An integrated regulome-interactome approach for establishing network regulation models in high-throughput screenings

PubMed Central

Rioualen, Claire; Da Costa, Quentin; Chetrit, Bernard; Charafe-Jauffret, Emmanuelle; Ginestier, Christophe

2017-01-01

High-throughput RNAi screenings (HTS) allow quantifying the impact of the deletion of each gene in any particular function, from virus-host interactions to cell differentiation. However, there has been less development for functional analysis tools dedicated to RNAi analyses. HTS-Net, a network-based analysis program, was developed to identify gene regulatory modules impacted in high-throughput screenings, by integrating transcription factors-target genes interaction data (regulome) and protein-protein interaction networks (interactome) on top of screening z-scores. HTS-Net produces exhaustive HTML reports for results navigation and exploration. HTS-Net is a new pipeline for RNA interference screening analyses that proves better performance than simple gene rankings by z-scores, by re-prioritizing genes and replacing them in their biological context, as shown by the three studies that we reanalyzed. Formatted input data for the three studied datasets, source code and web site for testing the system are available from the companion web site at http://htsnet.marseille.inserm.fr/. We also compared our program with existing algorithms (CARD and hotnet2). PMID:28949986

Influence of experimental methods on crossing in magnetic force-gap hysteresis curve of HTS maglev system

NASA Astrophysics Data System (ADS)

Lu, Yiyun; Qin, Yujie; Dang, Qiaohong; Wang, Jiasu

2010-12-01

The crossing in magnetic levitation force-gap hysteresis curve of melt high-temperature superconductor (HTS) vs. NdFeB permanent magnet (PM) was experimentally studied. One HTS bulk and PM was used in the experiments. Four experimental methods were employed combining of high/low speed of movement of PM with/without heat insulation materials (HIM) enclosed respectively. Experimental results show that crossing of the levitation force-gap curve is related to experimental methods. A crossing occurs in the magnetic force-gap curve while the PM moves approaching to and departing from the sample with high or low speed of movement without HIM enclosed. When the PM is enclosed with HIM during the measurement procedures, there is no crossing in the force-gap curve no matter high speed or low speed of movement of the PM. It was found experimentally that, with the increase of the moving speed of the PM, the maximum magnitude of levitation force of the HTS increases also. The results are interpreted based on Maxwell theories and flux flow-creep models of HTS.

Squid Giant Axon Contains Neurofilament Protein mRNA but does not Synthesize Neurofilament Proteins.

PubMed

Gainer, Harold; House, Shirley; Kim, Dong Sun; Chin, Hemin; Pant, Harish C

2017-04-01

When isolated squid giant axons are incubated in radioactive amino acids, abundant newly synthesized proteins are found in the axoplasm. These proteins are translated in the adaxonal Schwann cells and subsequently transferred into the giant axon. The question as to whether any de novo protein synthesis occurs in the giant axon itself is difficult to resolve because the small contribution of the proteins possibly synthesized intra-axonally is not easily distinguished from the large amounts of the proteins being supplied from the Schwann cells. In this paper, we reexamine this issue by studying the synthesis of endogenous neurofilament (NF) proteins in the axon. Our laboratory previously showed that NF mRNA and protein are present in the squid giant axon, but not in the surrounding adaxonal glia. Therefore, if the isolated squid axon could be shown to contain newly synthesized NF protein de novo, it could not arise from the adaxonal glia. The results of experiments in this paper show that abundant 3H-labeled NF protein is synthesized in the squid giant fiber lobe containing the giant axon's neuronal cell bodies, but despite the presence of NF mRNA in the giant axon no labeled NF protein is detected in the giant axon. This lends support to the glia-axon protein transfer hypothesis which posits that the squid giant axon obtains newly synthesized protein by Schwann cell transfer and not through intra-axonal protein synthesis, and further suggests that the NF mRNA in the axon is in a translationally repressed state.

Comprehensive Model of Jumbo Squid Dosidicus gigas Trophic Ecology in the Northern Humboldt Current System

PubMed Central

Alegre, Ana; Ménard, Frédéric; Tafur, Ricardo; Espinoza, Pepe; Argüelles, Juan; Maehara, Víctor; Flores, Oswaldo; Simier, Monique; Bertrand, Arnaud

2014-01-01

The jumbo squid Dosidicus gigas plays an important role in marine food webs both as predator and prey. We investigated the ontogenetic and spatiotemporal variability of the diet composition of jumbo squid in the northern Humboldt Current system. For that purpose we applied several statistical methods to an extensive dataset of 3,618 jumbo squid non empty stomachs collected off Peru from 2004 to 2011. A total of 55 prey taxa was identified that we aggregated into eleven groups. Our results evidenced a large variability in prey composition as already observed in other systems. However, our data do not support the hypothesis that jumbo squids select the most abundant or energetic taxon in a prey assemblage, neglecting the other available prey. Indeed, multinomial model predictions showed that stomach fullness increased with the number of prey taxa, while most stomachs with low contents contained one or two prey taxa only. Our results therefore question the common hypothesis that predators seek locally dense aggregations of monospecific prey. In addition D. gigas consumes very few anchovy Engraulis ringens in Peru, whereas a tremendous biomass of anchovy is potentially available. It seems that D. gigas cannot reach the oxygen unsaturated waters very close to the coast, where the bulk of anchovy occurs. Indeed, even if jumbo squid can forage in hypoxic deep waters during the day, surface normoxic waters are then required to recover its maintenance respiration (or energy?). Oxygen concentration could thus limit the co-occurrence of both species and then preclude predator-prey interactions. Finally we propose a conceptual model illustrating the opportunistic foraging behaviour of jumbo squid impacted by ontogenetic migration and potentially constrained by oxygen saturation in surface waters. PMID:24465788

Gradiometer Using Middle Loops as Sensing Elements in a Low-Field SQUID MRI System

NASA Technical Reports Server (NTRS)

Penanen, Konstantin; Hahn, Inseob; Ho Eom, Byeong

2009-01-01

A new gradiometer scheme uses middle loops as sensing elements in lowfield superconducting quantum interference device (SQUID) magnetic resonance imaging (MRI). This design of a second order gradiometer increases its sensitivity and makes it more uniform, compared to the conventional side loop sensing scheme with a comparable matching SQUID. The space between the two middle loops becomes the imaging volume with the enclosing cryostat built accordingly.

Relationships between morphometrical properties and the texture of an extrusion-expanded snack made from squid mantle (Dosidicus gigas).

PubMed

Valenzuela-Lagarda, José Luis; García-Armenta, Evangelina; Pacheco-Aguilar, Ramón; Gutiérrez-Dorado, Roberto; Mazorra-Manzano, Miguel Ángel; Lugo-Sánchez, María Elena; Muy-Rangel, María Dolores

2018-01-24

The giant squid (Dosidicus gigas) is a species of commercial interest as a source of protein, and it can be developed into ready-to-eat food products, including expanded extrusion snacks (EES). EES are prepared primarily from starch; however, adding animal protein increases the nutritional contents. The objective of this study was to evaluate the effect of the protein-carbohydrate interactions on the physical and morphological characteristics of an EES made of squid mantle and potato-corn flour. The independent variable was the squid mantle content (40, 60, 80, and 100%) and two controls (0 1  = 100% potato, 0 2  = 100% corn). The expansion rate (ER) of the sample is significantly minor (p < .5) when the squid mantle content increases ER = 2.0, 1.8 1.4 to 40, 60, and 80%, respectively. In samples with more protein, crispness and crunchiness were reduced, whereas the hardness increased. Digital imaging analysis indicated that the interaction between protein and starch causes significant morphometric changes to the fractal dimension (2.665-2.739) and lacunarity (0.61-1.29). The results showed that it is possible to incorporate up to 60% squid mantle to prepare EES that possess texture and morphometric characteristics competitive in reported studies with snacks usually incorporating flours, corn, and wheat in the formulations. The giant squid is a very attractive species because its meat has low caloric intake, high protein content, and is an important source of omega 3 fatty acids. Despite the desirable qualities of the squid meat its consumption is very low due to the low diffusion of the properties of its meat, acid, and ammoniacal flavor, rigid texture that requires prolonged cooking times and lack of alternatives of consumption. In Mexico, this type of squid is mainly destined for export as frozen mantle and products with little added value, which generates little economic benefit. Therefore, the results of this research may be of interest to the

Electrical and thermal characteristics of Bi2212/Ag HTS coils for conduction-cooled SMES

NASA Astrophysics Data System (ADS)

Hayakawa, N.; Noguchi, S.; Kurupakorn, C.; Kojima, H.; Endo, F.; Hirano, N.; Nagaya, S.; Okubo, H.

2006-06-01

In this paper, we investigated the electrical and thermal performance of conduction-cooled Bi2212/Ag HTS coils with 4K-GM cryocooler system. First, we measured the critical current Ic for different ambient temperatures T0 at 4.2 K - 40 K. Experimental results revealed that Ic increased with the decrease in T0 and was saturated at T0 < 10 K. We carried out thermal analysis considering heat generation, conduction and transfer under conduction-cooling condition, and reproduced the electrical and thermal characteristics of the conduction-cooled HTS coil, taking account of temperature dependence of specific heat and thermal conductivity of the materials. We also measured the temperature rise of Bi2212/Ag HTS coil for different continuous current levels at T0 = 4.8 K. Experimental results revealed the criterion of thermal runaway, which was discussed in terms of heat generation and propagation in the test coil.

TEM measurement in a low resistivity overburden performed by using low temperature SQUID

NASA Astrophysics Data System (ADS)

Ji, Yanju; Du, Shangyu; Xie, Lijun; Chang, Kai; Liu, Yang; Zhang, Yi; Xie, Xiaoming; Wang, Yuan; Lin, Jun; Rong, Liangliang

2016-12-01

Exploration of areas with thick low resistivity overburden is still a challenge for time domain transient electromagnetic method (TEM). We report modeling of a sandwich-layered earth by simulating the B field response with different conductive target layer thicknesses, thus obtaining a relationship between the resolution of the B field and the exploration depth. A low temperature Superconducting Quantum Interference Device (SQUID) is an ideal sensor for measuring the secondary magnetic field B in TEM measurements, because its sensitivity of several fT/√Hz is independent of frequency. In our TEM experiments, we utilized two different coils as receivers, a simple SQUID system, and a large transmitter loop of 200 × 200 m2 to compare the detected decay curves. At some measurement points, a decay signal of more than 300 ms duration was obtained by using the SQUID. Apparent resistivity profiles of about 9 km length are presented.

An active homopolar magnetic bearing with high temperature superconductor (HTS) coils and ferromagnetic cores

NASA Technical Reports Server (NTRS)

Brown, G. V.; Dirusso, E.; Provenza, A. J.

1995-01-01

A proof-of-feasibility demonstration showed that high temperature superconductor (HTS) coils can be used in a high-load, active magnetic bearing in liquid nitrogen. A homopolar radial bearing with commercially wound HTS (Bi 2223) bias and control coils produced over 200 lb (890 N) radial load capacity (measured non-rotating) and supported a shaft to 14000 rpm. The goal was to show that HTS coils can operate stably with ferromagnetic cores in a feedback controlled system at a current density similar to that in Cu in liquid nitrogen. Design compromises permitted use of circular coils with rectangular cross section. Conductor improvements will eventually permit coil shape optimization, higher current density and higher bearing load capacity. The bias coil, wound with non-twisted, multifilament HTS conductor, required negligible power to carry its direct current. The control coils were wound with monofilament HTS sheathed in Ag. These dissipated negligible power for direct current (i.e. for steady radial load components). When an alternating current (AC) was added, the AC component dissipated power which increased rapidly with frequency and quadratically with AC amplitude. In fact at frequencies above about 2 hz, the effective resistance of the control coil conductor actually exceeds that of the silver which is in electrical parallel with the oxide superconductor. This is at least qualitatively understandable in the context of a Bean-type model of flux and current penetration into a Type II superconductor. Fortunately the dynamic currents required for bearing stability are of small amplitude. These results show that while twisted multifilament conductor is not needed for stable levitation, twisted multifilaments will be required to reduce control power for sizable dynamic loads, such as those due to unbalance.

75 FR 1024 - Fisheries of the Northeastern United States; Atlantic Mackerel, Squid, and Butterfish Fisheries...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-08

... rulemaking (ANPR); notice to reaffirm the control date for the Loligo squid (Loligo) and Illex squid (Illex...: Public comments on the ANPR must be received no later than 5 p.m., eastern standard time, on February 8... fisheries since 2003. On May 20, 2003 (68 FR 27516), NMFS published, at the request of the Council, an ANPR...

Revealing the potential of squid chitosan-based structures for biomedical applications.

PubMed

Reys, L L; Silva, S S; Oliveira, J M; Caridade, S G; Mano, J F; Silva, T H; Reis, R L

2013-08-01

In recent years, much attention has been given to different marine organisms, namely as potential sources of valuable materials with a vast range of properties and characteristics. In this work, β-chitin was isolated from the endoskeleton of the giant squid Dosidicus gigas and further deacetylated to produce chitosan. Then, the squid chitosan was processed into membranes and scaffolds using solvent casting and freeze-drying, respectively, to assess their potential biomedical application. The developed membranes have shown to be stiffer and less hydrophobic than those obtained with commercial chitosan. On the other hand, the morphological characterization of the developed scaffolds, by SEM and micro-computed tomography, revealed that the matrices were formed with a lamellar structure. The findings also indicated that the treatment with ethanol prior to neutralization with sodium hydroxide caused the formation of larger pores and loss of some lamellar features. The in vitro cell culture study has shown that all chitosan scaffolds exhibited a non-cytotoxic effect over the mouse fibroblast-like cell line, L929 cells. Thus, chitosan produced from the endoskeletons of the giant squid Dosidicus gigas has proven to be a valuable alternative to existing commercial materials when considering its use as biomaterial.

ARQiv-HTS, a versatile whole-organism screening platform enabling in vivo drug discovery at high-throughput rates

PubMed Central

White, David T; Eroglu, Arife Unal; Wang, Guohua; Zhang, Liyun; Sengupta, Sumitra; Ding, Ding; Rajpurohit, Surendra K; Walker, Steven L; Ji, Hongkai; Qian, Jiang; Mumm, Jeff S

2017-01-01

The zebrafish has emerged as an important model for whole-organism small-molecule screening. However, most zebrafish-based chemical screens have achieved only mid-throughput rates. Here we describe a versatile whole-organism drug discovery platform that can achieve true high-throughput screening (HTS) capacities. This system combines our automated reporter quantification in vivo (ARQiv) system with customized robotics, and is termed ‘ARQiv-HTS’. We detail the process of establishing and implementing ARQiv-HTS: (i) assay design and optimization, (ii) calculation of sample size and hit criteria, (iii) large-scale egg production, (iv) automated compound titration, (v) dispensing of embryos into microtiter plates, and (vi) reporter quantification. We also outline what we see as best practice strategies for leveraging the power of ARQiv-HTS for zebrafish-based drug discovery, and address technical challenges of applying zebrafish to large-scale chemical screens. Finally, we provide a detailed protocol for a recently completed inaugural ARQiv-HTS effort, which involved the identification of compounds that elevate insulin reporter activity. Compounds that increased the number of insulin-producing pancreatic beta cells represent potential new therapeutics for diabetic patients. For this effort, individual screening sessions took 1 week to conclude, and sessions were performed iteratively approximately every other day to increase throughput. At the conclusion of the screen, more than a half million drug-treated larvae had been evaluated. Beyond this initial example, however, the ARQiv-HTS platform is adaptable to almost any reporter-based assay designed to evaluate the effects of chemical compounds in living small-animal models. ARQiv-HTS thus enables large-scale whole-organism drug discovery for a variety of model species and from numerous disease-oriented perspectives. PMID:27831568

High voltage insulation of bushing for HTS power equipment

NASA Astrophysics Data System (ADS)

Kim, Woo-Jin; Choi, Jae-Hyeong; Kim, Sang-Hyun

2012-12-01

For the operation of high temperature superconducting (HTS) power equipments, it is necessary to develop insulating materials and high voltage (HV) insulation technology at cryogenic temperature of bushing. Liquid nitrogen (LN2) is an attractive dielectric liquid. Also, the polymer insulating materials are expected to be used as solid materials such as glass fiber reinforced plastic (GFRP), polytetra-fluoroethylene (PTFE, Teflon), Silicon (Si) rubber, aromatic polyamide (Nomex), EPDM/Silicon alloy compound (EPDM/Si). In this paper, the surface flashover characteristics of various insulating materials in LN2 are studied. These results are studied at both AC and impulse voltage under a non-uniform field. The use of GFRP and Teflon as insulation body for HTS bushing should be much desirable. Especially, GFRP is excellent material not only surface flashover characteristics but also mechanical characteristics at cryogenic temperature. The surface flashover is most serious problem for the shed design in LN2 and operation of superconducting equipments.

The First Multichroic Polarimeter Array on the Atacama Cosmology Telescope: Characterization and Performance

NASA Astrophysics Data System (ADS)

Ho, S. P.; Pappas, C. G.; Austermann, J.; Beall, J. A.; Becker, D.; Choi, S. K.; Datta, R.; Duff, S. M.; Gallardo, P. A.; Grace, E.; Hasselfield, M.; Henderson, S. W.; Hilton, G. C.; Hubmayr, J.; Koopman, B. J.; Lanen, J. V.; Li, D.; McMahon, J.; Nati, F.; Niemack, M. D.; Niraula, P.; Salatino, M.; Schillaci, A.; Schmitt, B. L.; Simon, S. M.; Staggs, S. T.; Stevens, J. R.; Ward, J. T.; Wollack, E. J.; Vavagiakis, E. M.

2016-08-01

The Atacama Cosmology Telescope Polarimeter (ACTPol) is a polarization sensitive receiver for the 6-m Atacama Cosmology Telescope (ACT) and measures the small angular scale polarization anisotropies in the cosmic microwave background (CMB). The full focal plane is composed of three detector arrays, containing over 3000 transition edge sensors (TES detectors) in total. The first two detector arrays, observing at 146 GHz, were deployed in 2013 and 2014, respectively. The third and final array is composed of multichroic pixels sensitive to both 90 and 146 GHz and saw first light in February 2015. Fabricated at NIST, this dichroic array consists of 255 pixels, with a total of 1020 polarization sensitive bolometers and is coupled to the telescope with a monolithic array of broad-band silicon feedhorns. The detectors are read out using time-division SQUID multiplexing and cooled by a dilution refrigerator at 110 mK. We present an overview of the assembly and characterization of this multichroic array in the lab, and the initial detector performance in Chile. The detector array has a TES detector electrical yield of 85 %, a total array sensitivity of less than 10 \\upmu K√{ {s}}, and detector time constants and saturation powers suitable for ACT CMB observations.

The First Multichroic Polarimeter Array on the Atacama Cosmology Telescope: Characterization and Performance

NASA Technical Reports Server (NTRS)

Ho, S. P.; Pappas, C. G.; Austermann, J.; Beall, J. A.; Becker, D.; Choi, S. K.; Datta, R.; Duff, S. M.; Gallardo, P. A.; Grace, E.;

Performance evolution of 60 kA HTS cable prototypes in the EDIPO test facility

NASA Astrophysics Data System (ADS)

Bykovsky, N.; Uglietti, D.; Sedlak, K.; Stepanov, B.; Wesche, R.; Bruzzone, P.

2016-08-01

During the first test campaign of the 60 kA HTS cable prototypes in the EDIPO test facility, the feasibility of a novel HTS fusion cable concept proposed at the EPFL Swiss Plasma Center (SPC) was successfully demonstrated. While the measured DC performance of the prototypes at magnetic fields from 8 T to 12 T and for currents from 30 kA to 70 kA was close to the expected one, an initial electromagnetic cycling test (1000 cycles) revealed progressive degradation of the performance in both the SuperPower and SuperOx conductors. Aiming to understand the reasons for the degradation, additional cycling (1000 cycles) and warm up-cool down tests were performed during the second test campaign. I c performance degradation of the SuperOx conductor reached ∼20% after about 2000 cycles, which was reason to continue with a visual inspection of the conductor and further tests at 77 K. AC tests were carried out at 0 and 2 T background fields without transport current and at 10 T/50 kA operating conditions. Results obtained in DC and AC tests of the second test campaign are presented and compared with appropriate data published recently. Concluding the first iteration of the HTS cable development program at SPC, a summary and recommendations for the next activity within the HTS fusion cable project are also reported.

Effect of thermal processing and canning on cadmium and lead levels in California market squid: the role of metallothioneins.

PubMed

Galitsopoulou, A; Georgantelis, D; Kontominas, M G

2013-01-01

The effects of two common seafood preparation practices (roasting and industrial canning) on the heavy metal content--cadmium (Cd) and lead (Pb)--of various tissues of California market squid were studied. Emphasis was placed on the role of metallothioneins (MT) in Cd and Pb behaviour during processing. Cd and Pb analysis was conducted by a Zeeman GTA-AAS atomic absorption spectrometry system; MT analysis was performed by a mercury saturation assay. Results showed that Cd levels in the mantle and whole squid were considerably affected by both processing practices, reaching a 240% increase in mantle and a 40% increase in whole squid. Interestingly, Cd behaviour was associated with MT changes during squid processing. On the other hand, Pb content was not affected from either processing or associated with MT content in the raw or processed squid. Therefore, processing operations may affect Cd and Pb content differently due to the specific metal bioaccumulation and chemical features of each heavy metal type.

Enhanced HTS hit selection via a local hit rate analysis.

PubMed

Posner, Bruce A; Xi, Hualin; Mills, James E J

2009-10-01

The postprocessing of high-throughput screening (HTS) results is complicated by the occurrence of false positives (inactive compounds misidentified as active by the primary screen) and false negatives (active compounds misidentified as inactive by the primary screen). An activity cutoff is frequently used to select "active" compounds from HTS data; however, this approach is insensitive to both false positives and false negatives. An alternative method that can minimize the occurrence of these artifacts will increase the efficiency of hit selection and therefore lead discovery. In this work, rather than merely using the activity of a given compound, we look at the presence and absence of activity among all compounds in its "chemical space neighborhood" to give a degree of confidence in its activity. We demonstrate that this local hit rate (LHR) analysis method outperforms hit selection based on ranking by primary screen activity values across ten diverse high throughput screens, spanning both cell-based and biochemical assay formats of varying biology and robustness. On average, the local hit rate analysis method was approximately 2.3-fold and approximately 1.3-fold more effective in identifying active compounds and active chemical series, respectively, than selection based on primary activity alone. Moreover, when applied to finding false negatives, this method was 2.3-fold better than ranking by primary activity alone. In most cases, novel hit series were identified that would have otherwise been missed. Additional uses of and observations regarding this HTS analysis approach are also discussed.

Distributed Antenna-Coupled TES for FIR Detectors Arrays

NASA Technical Reports Server (NTRS)

Day, Peter K.; Leduc, Henry G.; Dowell, C. Darren; Lee, Richard A.; Zmuidzinas, Jonas

2007-01-01

We describe a new architecture for a superconducting detector for the submillimeter and far-infrared. This detector uses a distributed hot-electron transition edge sensor (TES) to collect the power from a focal-plane-filling slot antenna array. The sensors lay directly across the slots of the antenna and match the antenna impedance of about 30 ohms. Each pixel contains many sensors that are wired in parallel as a single distributed TES, which results in a low impedance that readily matches to a multiplexed SQUID readout These detectors are inherently polarization sensitive, with very low cross-polarization response, but can also be configured to sum both polarizations. The dual-polarization design can have a bandwidth of 50The use of electron-phonon decoupling eliminates the need for micro-machining, making the focal plane much easier to fabricate than with absorber-coupled, mechanically isolated pixels. We discuss applications of these detectors and a hybridization scheme compatible with arrays of tens of thousands of pixels.

Adsorption of Pb(II) and Cd(II) by Squid Ommastrephes bartrami Melanin

PubMed Central

Chen, Shiguo; Xue, Changhu; Wang, Jingfeng; Feng, Hui; Wang, Yuming; Ma, Qin; Wang, Dongfeng

2009-01-01

The adsorption of Cd(II) and Pb(II) by squid melanin was investigated. At a metal ion concentration of 2 mM/L, the biosorption efficiency of melanin reached 95% for Cd(II) and Pb(II). The maximum content of bound Cd(II) and Pb(II) was 0.93 mM/g and 0.65 mM/g, respectively. Temperature had no obvious effect on the adsorption of the metals, and in a pH range of 4.0–7.0, the adsorption yield was high and stable. Macrosalts such as NaCl, MgCl2, and CaCl2 had no obvious effect on the binding of Pb(II) but greatly diminished the adsorption of Cd(II), which indicated that different functional groups in squid melanin are responsible for their adsorption. IR analysis of metal ion-enriched squid melanin demonstrated that the possible functional groups responsible for metal binding were phenolic hydroxyl (OH), carboxyl (COOH), and amine groups (NH). This study reports a new material for the removal of heavy metals from low-strength wastewater. PMID:20148082

Quantum information transfer and entanglement with SQUID qubits in cavity QED: a dark-state scheme with tolerance for nonuniform device parameter.

PubMed

Yang, Chui-Ping; Chu, Shih-I; Han, Siyuan

2004-03-19

We investigate the experimental feasibility of realizing quantum information transfer (QIT) and entanglement with SQUID qubits in a microwave cavity via dark states. Realistic system parameters are presented. Our results show that QIT and entanglement with two-SQUID qubits can be achieved with a high fidelity. The present scheme is tolerant to device parameter nonuniformity. We also show that the strong coupling limit can be achieved with SQUID qubits in a microwave cavity. Thus, cavity-SQUID systems provide a new way for production of nonclassical microwave source and quantum communication.

A Possible Path from BCS through HTS to VHTS

NASA Astrophysics Data System (ADS)

Chu, C. W.

2010-03-01

Three years after celebrating the 50th anniversary of the BCS theory and the 20th anniversary of the discovery of high temperature superconductivity (HTS), it appears to be most fitting for us to contemplate the possibility of very high temperature superconductivity (VHTS). VHTS, preferably at room temperature, if achieved, could change the world both scientifically and technologically. Unfortunately, it has long been considered by some to belong to the domain of science fiction and to occur only ``at an astronomical distance and under an astronomical pressure.'' With the advent of liquid nitrogen superconductivity in 1987, the outlook has become much brighter. Currently, there appears to be no reason, either theoretical or experimental, why VHTS would be impossible, in spite of the 2006 prediction of the death of HTS by 2010-2015 through the so-called scientometric analysis of the publication record of the previous 20 years. The recent discovery of the new class of Fe-pnictide HTSs fuels more cautious optimism. Since its inception, BCS theory has provided the basic framework for the occurrence and understanding of superconductivity, but it has failed to show where and how to find superconductivity at a higher temperature. This may be attributed to the small energy scale of superconductivity in comparison with those of other excitations in the solids. After examining existing data, we believe that a holistic multidisciplinary enlightened empirical approach appears to be the most effective way to discover novel superconductors with higher transition temperatures. In this talk, I shall present several possible approaches toward VHTS that we are currently pursuing, after briefly summarizing what has happened in the long search for HTS and VHTS.

1 ATM subcooled liquid nitrogen cryogenic system with GM-refrigerator for a HTS power transformer

NASA Astrophysics Data System (ADS)

Yoshida, S.; Ohashi, K.; Umeno, T.; Suzuki, Y.; Kamioka, Y.; Kimura, H.; Tsutsumi, K.; Iwakuma, M.; Funaki, K.; Bhono, T.; Yagi, Y.

2002-05-01

A subcooled liquid nitrogen cryogenic system with GM-refrigerators was developed. The system was operated successfully in a commercial distribution power grid for three consecutive weeks without additional liquid nitrogen supply. The system consists of two main units. One is a HTS transformer unit and the HTS transformer is installed in a G-FRP cryostat. The other one is a pump unit. The pump unit has a liquid nitrogen pump and two GM-refrigerators of 290 W at 64 K for 50 Hz operation in a stainless steel dewar. The refrigerator cold heads are immersed in liquid nitrogen and produce directly subcooled liquid nitrogen in the pump unit. Those two units are connected by transfer-tubes and 1 atmosphere (0.1 MPa) subcooled liquid nitrogen is circulated through the system. In the field test, the refrigerators were operated at 60 Hz and it took 12 hours to cool the transformer down to 70 K and 26 hours to 66 K. The refrigerator cold heads were controlled not to be below 64 K during operation. In spite of a heat generation by the HTS transformer, the subcooled liquid nitrogen temperature in the HTS transformer unit was kept lower than 68 K.

The Hawaiian bobtail squid as a model system for selective particle capture in microfluidic systems.

NASA Astrophysics Data System (ADS)

Nawroth, Janna; McFall-Ngai, Margaret; Dabiri, John

2013-11-01

Juvenile Hawaiian bobtail squids reliably capture and isolate a single species of bacteria, Vibrio fischeri, from inhaled coastal water containing a huge background of living and non-living particles of comparable size. Biochemical mechanisms orchestrate a chain of specific interactions as soon as V.fischeri attach to the squid's internal light organ. It remains unclear, however, how the bacteria carried by the squid's ventilation currents are initially attracted to the light organ's surface. Here we present preliminary experimental data showing how arrangement and coordination of the cilia covering the light organ create a 3D flow field that facilitates advection, sieving and selective retention of flow-borne particles. These studies may inspire novel microfluidic tools for detection and capture of specific cells and particles.

Characterization and demonstration results of a SQUID magnetometer system developed for geomagnetic field measurements

NASA Astrophysics Data System (ADS)

Kawai, J.; Miyamoto, M.; Kawabata, M.; Nosé, M.; Haruta, Y.; Uehara, G.

2017-08-01

We characterized a low temperature superconducting quantum interference device (SQUID) magnetometer system developed for high-sensitivity geomagnetic field measurement, and demonstrated the detection of weak geomagnetic signals. The SQUID magnetometer system is comprised of three-axis SQUID magnetometers housed in a glass fiber reinforced plastic cryostat, readout electronics with flux locked loop (FLL), a 24-bit data logger with a global positioning system and batteries. The system noise was approximately 0.2 pT √Hz- 1/2 in the 1-50 Hz frequency range. This performance was determined by including the thermal noise and the shielding effect of the copper shield, which covered the SQUID magnetometers to eliminate high-frequency interference. The temperature drift of the system was ˜0.8 pT °C- 1 in an FLL operation. The system operated for a month using 33 l liquid helium. Using this system, we performed the measurements of geomagnetic field in the open-air, far away from the city. The system could detect weak geomagnetic signals such as the Schumann resonance with sixth harmonics, and the ionospheric Alfvén resonance appearing at night, for the north-south and east-west components of the geomagnetic field. We confirm that the system was capable of high-sensitivity measurement of the weak geomagnetic activities.

Loudness-dependent behavioral responses and habituation to sound by the longfin squid (Doryteuthis pealeii).

PubMed

Mooney, T Aran; Samson, Julia E; Schlunk, Andrea D; Zacarias, Samantha

2016-07-01

Sound is an abundant cue in the marine environment, yet we know little regarding the frequency range and levels which induce behavioral responses in ecologically key marine invertebrates. Here we address the range of sounds that elicit unconditioned behavioral responses in squid Doryteuthis pealeii, the types of responses generated, and how responses change over multiple sound exposures. A variety of response types were evoked, from inking and jetting to body pattern changes and fin movements. Squid responded to sounds from 80 to 1000 Hz, with response rates diminishing at the higher and lower ends of this frequency range. Animals responded to the lowest sound levels in the 200-400 Hz range. Inking, an escape response, was confined to the lower frequencies and highest sound levels; jetting was more widespread. Response latencies were variable but typically occurred after 0.36 s (mean) for jetting and 0.14 s for body pattern changes; pattern changes occurred significantly faster. These results demonstrate that squid can exhibit a range of behavioral responses to sound include fleeing, deimatic and protean behaviors, all of which are associated with predator evasion. Response types were frequency and sound level dependent, reflecting a relative loudness concept to sound perception in squid.

SQUID magnetometry from nanometer to centimeter length scales

NASA Astrophysics Data System (ADS)

Hatridge, Michael Jonathan

Information stored in magnetic fields plays an important role in everyday life. This information exists over a remarkably wide range of sizes, so that magnetometry at a variety of length scales can extract useful information. Examples at centimeter to millimeter length scales include measurement of spatial and temporal character of fields generated in the human brain and heart, and active manipulation of spins in the human body for non-invasive magnetic resonance imaging (MRI). At micron length scales, magnetometry can be used to measure magnetic objects such as flux qubits; at nanometer length scales it can be used to study individual magnetic domains, and even individual spins. The development of Superconducting QUantum Interference Device (SQUID) based magnetometer for two such applications, in vivo prepolarized, ultra-low field MRI of humans and dispersive readout of SQUIDs for micro- and nanoscale magnetometry, are the focus of this thesis. Conventional MRI has developed into a powerful clinical tool for imaging the human body. This technique is based on nuclear magnetic resonance of protons with the addition application of three-dimensional magnetic field gradients to encode spatial information. Most clinical MRI systems involve magnetic fields generated by superconducting magnets, and the current trend is to higher magnetic fields than the widely used 1.5-T systems. Nonetheless, there is ongoing interest in the development of less expensive imagers operating at lower fields. The prepolarized, SQUID detected ultra-low field MRI (ULF MRI) developed by the Clarke group allows imaging in very weak fields (typically 132 muT, corresponding to a resonant frequency of 5.6 kHz). At these low field strengths, there is enhanced contrast in the longitudinal relaxation time of various tissue types, enabling imaging of objects which are not visible to conventional MRI, for instance prostate cancer. We are currently investigating the contrast between normal and cancerous

Pathway Profiling and Tissue Modeling Using ToxCast HTS Data

EPA Science Inventory

High-throughput screening (HTS) and high-content screening (HCS) assays are providing data-rich studies to probe and profile the direct cellular effects of thousands of chemical compounds in commerce or potentially entering the environment. In vitro profiling may compare unknown ...

Effect of Melanin Free Ink Extracted From Squid (Loligo sp.) on Proximate and Sensory Characteristics of Soft-Bone Milkfish (Chanos chanos) During Storage

NASA Astrophysics Data System (ADS)

Winarni Agustini, Tri; Hadiyanto; Wijayanti, Ima; Amalia, Ulfah; Benjakul, Soottawat

2018-02-01

Antioxidant could be extracted and isolated from squid inks. Squid ink in the form of melanin free ink (MFI) could be act as an electron donor which can stabilize free radicals in lipid oxidation. This study was carried out to assess the antioxidant activity of squid inks converted into MFI in different dilution and to optimize the extraction conditions for the application of MFI as an antioxidative agent on fish product. Three different types of MFI extracts i.e : pure squid ink, squid ink with 5 times dilution and squid ink with 10 times dilutions by using cooled ionized water (4°C). The ink was then centrifuged at 18.000 x g for 30 minutes at cooled centrifuge (4°C) followed by DPPH analysis. The results showed that the IC50 of MFI extracts were 2.84 ppm; 1.11 ppm and 0.34 ppm, respectively (p < 0.05). The results indicated that squid ink with 10 times dilution in extraction of MFI had the highest value in free radical inhibitory. Although the IC50 of three different dilutions are equally low, and are considered as very strong antioxidative agent, however, it showed that the MFI extracted from squid ink had the ability to prevent free radical

The giant eyes of giant squid are indeed unexpectedly large, but not if used for spotting sperm whales.

PubMed

Nilsson, Dan-E; Warrant, Eric J; Johnsen, Sönke; Hanlon, Roger T; Shashar, Nadav

2013-09-08

We recently reported (Curr Biol 22:683-688, 2012) that the eyes of giant and colossal squid can grow to three times the diameter of the eyes of any other animal, including large fishes and whales. As an explanation to this extreme absolute eye size, we developed a theory for visual performance in aquatic habitats, leading to the conclusion that the huge eyes of giant and colossal squid are uniquely suited for detection of sperm whales, which are important squid-predators in the depths where these squid live. A paper in this journal by Schmitz et al. (BMC Evol Biol 13:45, 2013) refutes our conclusions on the basis of two claims: (1) using allometric data they argue that the eyes of giant and colossal squid are not unexpectedly large for the size of the squid, and (2) a revision of the values used for modelling indicates that large eyes are not better for detection of approaching sperm whales than they are for any other task. We agree with Schmitz et al. that their revised values for intensity and abundance of planktonic bioluminescence may be more realistic, or at least more appropriately conservative, but argue that their conclusions are incorrect because they have not considered some of the main arguments put forward in our paper. We also present new modelling to demonstrate that our conclusions remain robust, even with the revised input values suggested by Schmitz et al.

Characterization of Hybrid Ferroelectric/HTS Thin Films for Tunable Microwave Components

NASA Technical Reports Server (NTRS)

Winters, M. D.; Mueller, C. H.; Bhasin, K. B.; Miranda, F. A.

1996-01-01

Since the discovery of High-Temperature-Superconductors (HTS) in 1986, a diversity of HTS-based microwave components has been demonstrated. Because of their low conductor losses, HTS-based components are very attractive for integration into microwave circuits for space communication systems. Recent advancements have made deposition of ferroelectric thin films onto HTS thin films possible. Due to the sensitivity of the ferroelectric's dielectric constant (epsilon(sub r)) to an externally applied electric field (E), ferroelectric/superconducting structures could be used in the fabrication of low loss, tunable microwave components. In this paper, we report on our study of Ba(0.5)Sr(0.5)TiO3/YBa2Cu3O(7-delta) and Ba(0.08)Sr(0.92)TiO3/YBa2Cu3O(7-delta) ferroelectric/superconducting thin films on lanthanum aluminate (LaAlO3) substrates. For the (Ba:Sr, 0.50:0.50) epitaxial sample, a epsilon(sub r) of 425 and a loss tangent (tan delta) of 0.040 were measured at 298 K, 1.0 MHz, and zero applied E. For the same sample, a epsilon(sub r) of 360 and tan delta of 0.036 were obtained at 77 K, 1.0 MHz, and zero applied E. Variations in epsilon(sub r) from 180 to 360 were observed over an applied E range of 0V/cm less than or equal to E less than or equal to 5.62 x 10(exp 4) V/cm with little change in tan delta. However, the range of epsilon(sub r) variation for the polycrystalline (Ba:Sr, 0.08:0.92) sample over 0V/cm less than or equal to E less than or equal to 4.00 x 10(exp 4) V/cm was only 3.6 percent while tan delta increased markedly. These results indicate that a lack of epitaxy between the ferroelectric and superconducting layers decreases tuning and increases microwave losses.

ESR studies on the thermal decomposition of trimethylamine oxide to formaldehyde and dimethylamine in jumbo squid (Dosidicus gigas) extract.

PubMed

Zhu, Junli; Jia, Jia; Li, Xuepeng; Dong, Liangliang; Li, Jianrong

2013-12-15

The effects of ferrous iron, heating temperature and different additives on the decomposition of trimethylamine oxide (TMAO) to formaldehyde (FA) and dimethylamine (DMA) and generation of free radicals in jumbo squid (Dosidicus gigas) extract during heating were evaluated by electron spin resonance (ESR). The thermal decomposition of TMAO to TMA, DMA and FA and free radical signals was observed in squid extract, whereas no DMA, FA and free radical signals were detected in cod extract or in aqueous TMAO solution in vitro at high temperatures. Significant increase in levels of DMA, FA and radicals intensity were observed in squid extract and TMAO solution in the presence of ferrous iron with increasing temperature. Hydrogen peroxide stimulated the production of DMA, FA and ESR signals in squid extract, while citric acid, trisodium citrate, calcium chloride, tea polyphenols and resveratrol had the opposite effect. Similar ESR spectra of six peaks regarded as amminium radical were detected in the squid extract and TMAO-iron(II) solution, suggesting that the amminium radical was involved in the decomposition of TMAO. Copyright © 2013 Elsevier Ltd. All rights reserved.

A compact 3 T all HTS cryogen-free MRI system

NASA Astrophysics Data System (ADS)

Parkinson, B. J.; Bouloukakis, K.; Slade, R. A.

2017-12-01

We have designed and built a passively shielded, cryogen-free 3 T 160 mm bore bismuth strontium calcium copper oxide HTS magnet with shielded gradient coils suitable for use in small animal imaging applications. The magnet is cooled to approximately 16 K using a two-stage cryocooler and is operated at 200 A. The magnet has been passively shimmed so as to achieve ±10 parts per million (ppm) homogeneity over a 60 mm diameter imaging volume. We have demonstrated that B 0 temporal stability is fit-for-purpose despite the magnet operating in the driven mode. The system has produced good quality spin-echo and gradient echo images. This compact HTS-MRI system is emerging as a true alternative to conventional low temperature superconductor based cryogen-free MRI systems, with much more efficient cryogenics since it operates entirely from a single phase alternating current electrical supply.

High temperature superconductor micro-superconducting-quantum-interference-device magnetometer for magnetization measurement of a microscale magnet.

PubMed

Takeda, Keiji; Mori, Hatsumi; Yamaguchi, Akira; Ishimoto, Hidehiko; Nakamura, Takayoshi; Kuriki, Shinya; Hozumi, Toshiya; Ohkoshi, Shin-ichi

2008-03-01

We have developed a high temperature superconductor (HTS) micrometer-sized dc superconducting quantum interference device (SQUID) magnetometer for high field and high temperature operation. It was fabricated from YBa2Cu3O7-delta of 92 nm in thickness with photolithography techniques to have a hole of 4x9 microm2 and 2 microm wide grain boundary Josephson junctions. Combined with a three dimensional magnetic field coil system, the modulation patterns of critical current Ic were observed for three different field directions. They were successfully used to measure the magnetic properties of a molecular ferrimagnetic microcrystal (23x17x13 microm3), [Mn2(H2O)2(CH3COO)][W(CN)8]2H2O. The magnetization curve was obtained in magnetic field up to 0.12 T between 30 and 70 K. This is the first to measure the anisotropy of hysteresis curve in the field above 0.1 T with an accuracy of 10(-12) J T(-1) (10(-9) emu) with a HTS micro-SQUID magnetometer.

Influence of Off-Centre Operation on the Performance of HTS Maglev

NASA Astrophysics Data System (ADS)

Gou, Y.; He, D.; Zheng, J.; Ye, C.; Xu, Y.; Sun, R.; Che, T.; Deng, Z.

2014-03-01

Owing to instinctive self-stable levitation characteristics, high-temperature superconducting (HTS) maglev using bulk high-temperature superconductors attracts more and more attention from scientists and engineers around the world. In this paper, the levitation force relaxation and guidance force characteristics of a Y-Ba-Cu-O levitation unit with different eccentric distances (EDs) off the center of the permanent magnet guideway were experimentally investigated under field-cooling (FC) conditions. Experimental results indicate that the levitation force slightly increases at small EDs firstly, but degrades with further increasing of EDs. However, the maximum guidance force and its stiffness exhibit enhancement in moderate ED range. The results demonstrate that a properly designed initial FC eccentric distance is important for the practical applications of HTS maglev according to specific requirements like running in curve lines.

Design of Conduction-cooled HTS Coils for a Rotating Gantry

NASA Astrophysics Data System (ADS)

Takayama, Shigeki; Koyanagi, Kei; Yamaguchi, Akiko; Tasaki, Kenji; Kurusu, Tsutomu; Ishii, Yusuke; Amemiya, Naoyuki; Ogitsu, Toru; Noda, Koji

Carbon ion cancer therapy is becoming more widespread due to its high curative effects and low burden on patients. Carbon ions are delivered to patients through electromagnets on a rotating gantry.A rotating gantry is attractive because it allows carbon ions to irradiate a tumor from any direction without changing the posture of the patient. On the other hand, because of the high magnetic rigidity of carbon ions, the weight of a rotating gantry for carbon cancer therapy is about three times higher than one for proton cancer therapy, according to our estimation. The use of high-temperature superconducting (HTS) magnets has been considered for reducing the size of the rotating gantry for carbon cancer therapy. The target weight is 200 t or less,which is equivalent to the weight of a typical rotating gantry for proton cancer therapy.In this study, the magnet layout of the rotating gantry and the superconducting magnets were designed from the viewpoint of beam optics.When applying high-temperature superconductors to accelerator magnets, there are some issues that should be considered, for example, the influence of tape magnetization and manufacturing accuracy on the field quality, the thermal stability of the conduction-cooled HTS coils under an alternating magnetic field, and methods to protect the coils from thermal runaway caused by an anomalous thermal input such as that due to beam loss. First, the thermal stability of the conduction-cooled HTS coils was simulated numerically, and the thermal runaway current was calculated in a static situation.

Large format imaging arrays for the Atacama Cosmology Telescope

NASA Technical Reports Server (NTRS)

Chervenak, J. A.; Wollack, E. J.; Marraige, T.; Staggs, S.; Niemack, M.; Doriese, B.

2006-01-01

We describe progress in the fabrication, characterization, and production of detector arrays for the Atacama Cosmology Telescope (ACT). The completed ACT instrument is specified to image simultaneously at 145, 225, and 265 GHz using three 32x32 filled arrays of superconducting transition edge sensors (TES) read out with time-division-multiplexed SQUID amplifiers. We present details of the pixel design and testing including the optimization of the electrical parameters for multiplexed readout. Using geometric noise suppression and careful tuning of operation temperature and device bias resistance, the excess noise in the TES devices is balanced with detector speed for interfacing with the ACT optics. The design also accounts for practical tolerances such as transition temperature gradients and scatter that occur in the production of multiple wafers to populate fully the kilopixel cameras. We have developed an implanted absorber layer compatible with our silicon-on-insulator process that allows for tunable optical resistance with requisite on-wafer uniformity and wafer-to-wafer reproducibility. Arrays of 32 elements have been tested in the laboratory environment including electrical, optical, and multiplexed performance. Given this pixel design, optical tests and modeling are used to predict the performance of the filled array under anticipated viewing conditions. Integration of the filled array of pixels with a tuned backshort and dielectric plate in front of the array maximize absorption and the focal plane and suppress reflections. A mechanical design for the build of the full structure is completed and we report on progress toward the construction of a prototype array for first light on the ACT.

2G HTS wires made on 30 μm thick Hastelloy substrate

NASA Astrophysics Data System (ADS)

Sundaram, A.; Zhang, Y.; Knoll, A. R.; Abraimov, D.; Brownsey, P.; Kasahara, M.; Carota, G. M.; Nakasaki, R.; Cameron, J. B.; Schwab, G.; Hope, L. V.; Schmidt, R. M.; Kuraseko, H.; Fukushima, T.; Hazelton, D. W.

2016-10-01

REBCO (RE = rare earth) based high temperature superconducting (HTS) wires are now being utilized for the development of electric and electromagnetic devices for various industrial, scientific and medical applications. In the last several years, the increasing efforts in using the so-called second generation (2G) HTS wires for some of the applications require a further increase in their engineering current density (J e). The applications are those typically related to high magnetic fields where the higher J e of a REBCO wire, in addition to its higher irreversibility fields and higher mechanical strength, is already a major advantage over other superconducting wires. An effective way to increase the J e is to decrease the total thickness of a wire, for which using a thinner substrate becomes an obvious and attractive approach. By using our IBAD-MOCVD (ion beam assisted deposition-metal organic chemical vapor deposition) technology we have successfully made 2G HTS wires using a Hastelloy® C276 substrate that is only 30 μm in thickness. By using this thinner substrate instead of the typical 50 μm thick substrate and with a same critical current (I c), the J e of a wire can be increased by 30% to 45% depending on the copper stabilizer thickness. In this paper, we report the fabrication and characterization of the 2G HTS wires made on the 30 μm thick Hastelloy® C276 substrate. It was shown that with the optimization in the processing protocol, the surface of the thinner Hastelloy® C276 substrate can be readily electropolished to the quality needed for the deposition of the buffer stack. Same in the architecture as that on the standard 50 μm thick substrate, the buffer stack made on the 30 μm thick substrate showed an in-plane texture with a Δϕ of around 6.7° in the LaMnO3 cap layer. Low-temperature in-field transport measurement results suggest that the wires on the thinner substrate had achieved equivalent superconducting performance, most importantly the I

Plate-fin Heat-exchangers for a 10 kW Brayton Cryocooler and a 1 km HTS Cable

NASA Astrophysics Data System (ADS)

Chang, Ho-Myung; Gwak, Kyung Hyun; Jung, Seyong; Yang, Hyung Suk; Hwang, Si-Dole

Plate-fin heat exchangers (PFHX) are designed and fabricated for a cryogenic cooling system, serving for a 10 kW Brayton cryocooler and a 1 km HTS transmission cable under development in Korea. To achieve compactness and thermal efficiency at the same time, a recuperative HX for Brayton cycle and a sub-cooling HX of liquid nitrogen for HTS cable are designed as integrated parts. A key design feature is focused on the coldest part of sub-cooling HX, where the streams of liquid nitrogen and refrigerant (helium gas) are arranged as two-pass cross-flow so that the risk of freeze-out of liquid nitrogen can be reduced. Details of hardware PFHX design are presented and discussed towards its immediate application to the HTS cable system.

Sequential isotopic signature along gladius highlights contrasted individual foraging strategies of jumbo squid (Dosidicus gigas).

PubMed

Lorrain, Anne; Argüelles, Juan; Alegre, Ana; Bertrand, Arnaud; Munaron, Jean-Marie; Richard, Pierre; Cherel, Yves

2011-01-01

Cephalopods play a major role in marine ecosystems, but knowledge of their feeding ecology is limited. In particular, intra- and inter-individual variations in their use of resources has not been adequatly explored, although there is growing evidence that individual organisms can vary considerably in the way they use their habitats and resources. Using δ(13)C and δ(15)N values of serially sampled gladius (an archival tissue), we examined high resolution variations in the trophic niche of five large (>60 cm mantle length) jumbo squids (Dosidicus gigas) that were collected off the coast of Peru. We report the first evidence of large inter-individual differences in jumbo squid foraging strategies with no systematic increase of trophic level with size. Overall, gladius δ(13)C values indicated one or several migrations through the squid's lifetime (∼8-9 months), during which δ(15)N values also fluctuated (range: 1 to 5‰). One individual showed an unexpected terminal 4.6‰ δ(15)N decrease (more than one trophic level), thus indicating a shift from higher- to lower-trophic level prey at that time. The data illustrate the high diversity of prey types and foraging histories of this species at the individual level. The isotopic signature of gladii proved to be a powerful tool to depict high resolution and ontogenic variations in individual foraging strategies of squids, thus complementing traditional information offered by stomach content analysis and stable isotopes on metabolically active tissues. The observed differences in life history strategies highlight the high degree of plasticity of the jumbo squid and its high potential to adapt to environmental changes.

Sequential Isotopic Signature Along Gladius Highlights Contrasted Individual Foraging Strategies of Jumbo Squid (Dosidicus gigas)

PubMed Central

Lorrain, Anne; Argüelles, Juan; Alegre, Ana; Bertrand, Arnaud; Munaron, Jean-Marie; Richard, Pierre; Cherel, Yves

2011-01-01

Background Cephalopods play a major role in marine ecosystems, but knowledge of their feeding ecology is limited. In particular, intra- and inter-individual variations in their use of resources has not been adequatly explored, although there is growing evidence that individual organisms can vary considerably in the way they use their habitats and resources. Methodology/Principal Findings Using δ13C and δ15N values of serially sampled gladius (an archival tissue), we examined high resolution variations in the trophic niche of five large (>60 cm mantle length) jumbo squids (Dosidicus gigas) that were collected off the coast of Peru. We report the first evidence of large inter-individual differences in jumbo squid foraging strategies with no systematic increase of trophic level with size. Overall, gladius δ13C values indicated one or several migrations through the squid's lifetime (∼8–9 months), during which δ15N values also fluctuated (range: 1 to 5‰). One individual showed an unexpected terminal 4.6‰ δ15N decrease (more than one trophic level), thus indicating a shift from higher- to lower-trophic level prey at that time. The data illustrate the high diversity of prey types and foraging histories of this species at the individual level. Conclusions/Significance The isotopic signature of gladii proved to be a powerful tool to depict high resolution and ontogenic variations in individual foraging strategies of squids, thus complementing traditional information offered by stomach content analysis and stable isotopes on metabolically active tissues. The observed differences in life history strategies highlight the high degree of plasticity of the jumbo squid and its high potential to adapt to environmental changes. PMID:21779391

Numerical studies on the force characteristic of superconducting linear synchronous motor with HTS bulk magnet

NASA Astrophysics Data System (ADS)

Tang, Junjie; Li, Jing; Li, Xiang; Han, Le

2018-03-01

High temperature superconductor (HTS) bulks have significant potential use in linear motor application act as quasi-permanent magnet to replace traditional magnets. Force characteristic between HTS bulk magnet and traveling magnetic field was investigated with numerical simulation and experimental measurement in this paper. Influences of bulk height and number on the force characteristic were studied by the finite element model considering the nonlinear E-J relationship. Study was also made on addition of a back iron plate to the bulk magnet. Besides, force characteristic of bulk was compared with the permanent magnet results. The small initial decrease of the thrust could be explained by inside superconducting current redistribution. It was found that efficiency of linear motor did not increase by adding more bulk magnets. The bulk magnet will be remagnetized instead of erasing trapped field with the increase of the traveling magnetic field strength. The conclusions are helpful in prediction and design the linear motor with HTS bulk magnet.

The jumbo squid, Dosidicus gigas (Ommastrephidae), living in oxygen minimum zones II: Blood-oxygen binding

NASA Astrophysics Data System (ADS)

Seibel, Brad A.

2013-10-01

Dosidicus gigas is a large, metabolically active squid that migrates across a strong oxygen and temperature gradient in the Eastern Pacific. Here we analyze the oxygen-binding properties of the squid's respiratory protein (hemocyanin, Hc) that facilitate such activity. A high Hc-oxygen affinity, strong temperature dependence, and pronounced pH sensitivity (P50=0.009T2.03, pH 7.4; Bohr coefficient=ΔlogP50/ΔpH=-1.55+0.034T) of oxygen binding facilitate night-time foraging in the upper water column, and support suppressed oxygen demand in hypoxic waters at greater depths. Expanding hypoxia may act to alter the species habitable depth range. This analysis supports the contention that ocean acidification could limit oxygen carrying capacity in squids at warmer temperature leading to reduced activity levels or altered distribution.

Research on Intelligent Control System of DC SQUID Magnetometer Parameters for Multi-channel System

NASA Astrophysics Data System (ADS)

Chen, Hua; Yang, Kang; Lu, Li; Kong, Xiangyan; Wang, Hai; Wu, Jun; Wang, Yongliang

2018-07-01

In a multi-channel SQUID measurement system, adjusting device parameters to optimal condition for all channels is time-consuming. In this paper, an intelligent control system is presented to determine the optimal working point of devices which is automatic and more efficient comparing to the manual one. An optimal working point searching algorithm is introduced as the core component of the control system. In this algorithm, the bias voltage V_bias is step scanned to obtain the maximal value of the peak-to-peak current value I_pp of the SQUID magnetometer modulation curve. We choose this point as the optimal one. Using the above control system, more than 30 weakly damped SQUID magnetometers with area of 5 × 5 mm^2 or 10 × 10 mm^2 are adjusted and a 36-channel magnetocardiography system perfectly worked in a magnetically shielded room. The average white flux noise is 15 {μ Φ }_0/Hz^{1/2}.

Research on Intelligent Control System of DC SQUID Magnetometer Parameters for Multi-channel System

NASA Astrophysics Data System (ADS)

Chen, Hua; Yang, Kang; Lu, Li; Kong, Xiangyan; Wang, Hai; Wu, Jun; Wang, Yongliang

2018-03-01

In a multi-channel SQUID measurement system, adjusting device parameters to optimal condition for all channels is time-consuming. In this paper, an intelligent control system is presented to determine the optimal working point of devices which is automatic and more efficient comparing to the manual one. An optimal working point searching algorithm is introduced as the core component of the control system. In this algorithm, the bias voltage V_bias is step scanned to obtain the maximal value of the peak-to-peak current value I_pp of the SQUID magnetometer modulation curve. We choose this point as the optimal one. Using the above control system, more than 30 weakly damped SQUID magnetometers with area of 5 × 5 mm^2 or 10 × 10 mm^2 are adjusted and a 36-channel magnetocardiography system perfectly worked in a magnetically shielded room. The average white flux noise is 15 μΦ_0/Hz^{1/2}.

Analysis and experimental study of wireless power transfer with HTS coil and copper coil as the intermediate resonators system

NASA Astrophysics Data System (ADS)

Wang, Xiufang; Nie, Xinyi; Liang, Yilang; Lu, Falong; Yan, Zhongming; Wang, Yu

2017-01-01

Intermediate resonator (repeater) between transmitter and receiver can significantly increase the distance of wireless power transfer (WPT) and the efficiency of wireless power transfer. The wireless power transfer via strongly coupled magnetic resonances with an high temperature superconducting (HTS) coil and copper coil as intermediate resonators was presented in this paper. The electromagnetic experiment system under different conditions with different repeating coils were simulated by finite element software. The spatial distribution patterns of magnetic induction intensity at different distances were plotted. In this paper, we examined transfer characteristics with HTS repeating coil and copper repeating coil at 77 K and 300 K, respectively. Simulation and experimental results show that HTS and copper repeating coil can effectively enhance the space magnetic induction intensity, which has significant effect on improving the transmission efficiency and lengthening transmission distance. We found that the efficiency and the distance of wireless power transfer system with an HTS coil as repeater is much higher by using of copper coil as repeater.

A method to enhance the curve negotiation performance of HTS Maglev

NASA Astrophysics Data System (ADS)

Che, T.; Gou, Y. F.; Deng, Z. G.; Zheng, J.; Zheng, B. T.; Chen, P.

2015-09-01

High temperature superconducting (HTS) Maglev has attracted more and more attention due to its special self-stable characteristic, and much work has been done to achieve its actual application, but the research about the curve negotiation is not systematic and comprehensive. In this paper, we focused on the change of the lateral displacements of the Maglev vehicle when going through curves under different velocities, and studied the change of the electromagnetic forces through experimental methods. Experimental results show that setting an appropriate initial eccentric distance (ED), which is the distance between the center of the bulk unit and the center of the permanent magnet guideway (PMG), when cooling the bulks is favorable for the Maglev system’s curve negotiation. This work will provide some available suggestions for improving the curve negotiation performance of the HTS Maglev system.

Habitat and distribution of post-recruit life stages of the squid Loligo forbesii

NASA Astrophysics Data System (ADS)

Smith, Jennifer M.; Macleod, Colin D.; Valavanis, Vasilis; Hastie, Lee; Valinassab, Tooraj; Bailey, Nick; Santos, M. Begoña; Pierce, Graham J.

2013-10-01

This study models habitat preferences of the squid Loligo forbesii through its post-recruitment life cycle in waters around Scotland (UK). Trawl survey and market sample data from 1985 to 2004 are used to model seasonal habitats of immature, maturing and mature squid (maturity being inferred from size and season). Squid presence-absence and catch rate in areas of presence were analysed using generalised additive models, relating spatiotemporal patterns of distribution and abundance to ecogeographic variables. For all maturity classes, higher abundance in winter and spring (i.e., quarters 1 and 2) was associated with deeper water while higher abundance in summer and autumn (quarters 3 and 4) was associated with shallower water, consistent with seasonal onshore-offshore migrations but suggesting that most spawning may take place in deeper waters. The preferred SST range was generally 8-8.75 °C while preferred salinity values were below 35‰ in winter and summer and above 35‰ in spring and autumn. Squid were positively associated with gravel substrate and negatively associated with mud. Seasonal changes in habitat use were more clearly evident than changes related to inferred maturity, although the two effects cannot be fully separated due to the annual life cycle. Habitat selection for this species can be satisfactorily modelled on a seasonal basis; predictions based on such models could be useful for fishers to target the species more effectively, and could assist managers wishing to protect spawning grounds. The extent to which this approach may be useful for other cephalopods is discussed.

Y1Ba2Cu3O(7-delta) thin film dc SQUIDs (superconducting quantum interference device)

NASA Astrophysics Data System (ADS)

Racah, Daniel

1991-03-01

Direct current superconducting quantum interferometers (SQUIDs) based on HTSC thin films have been measured and characterized. The thin films used were of different quality: (1) Granular films on Sapphire substrates, prepared either by e-gun evaporation, by laser ablation or by MOCVD (metal oxide chemical vapor deposition), (2) Epitaxial films on MgO substrates. Modulations of the voltage on the SQUIDs as a function of the applied flux have been observed in a wide range of temperatures. The nature of the modulation was found to be strongly dependent on the morphology of the film and on its critical current. The SQUIDs based on granular films were relatively noisy, hysteretic and with a complicated V-phi shape. Those devices based on low quality (lowIc) granular films could be measured only at low temperatures (much lower than 77 K). While those of higher quality (granular films with high Ic) could be measured near to the superconductive transition. The SQUID based on high quality epitaxial film was measured near Tc and showed an anomalous, time dependent behavior.

A SQUID-Based RF Cavity Search for Dark Matter Axions

NASA Astrophysics Data System (ADS)

Hotz, Michael T.

The axion is a hypothetical elementary particle resulting from a solution to the "Strong-CP" problem. This serious problem in the standard model of particle physics is manifested as a 1010 discrepancy between the measured upper limit and the calculated value of the neutron's electric dipole moment. Furthermore, a light (~mueV) axion is an ideal dark matter candidate: axions would have been copiously produced during the Big Bang and would be the primary component of the dark matter in the universe. The resolution of the Strong-CP problem and the discovery of the composition of dark matter are two of the most pressing problems in physics. The observation of a light, dark-matter axion would resolve both of these problems. The Axion Dark Matter eXperiment (ADMX) is the most sensitive search for dark-matter axions. Axions in our Milky Way Galaxy may scatter off a magnetic field and convert into microwave photons. ADMX consists of a tunable high-Q RF cavity within the bore of a large, 8.5 Tesla superconducting solenoidal magnet. When the cavity's resonant frequency matches the axion's total energy, the probability of axion-to-photon conversion is enhanced. The cavity's narrow bandwidth requires ADMX to slowly scan possible axion masses. A receiver amplifies, mixes, and digitizes the power developed in the cavity from possible axion-to-photon conversions. This is the most sensitive spectral receiver of microwave radiation in the world. The resulting data is scrutinized for an axion signal above the thermal background. ADMX first operated from 1995-2005 and produced exclusion limits on the energy of dark-matter axions from 1.9 mueV to 3.3 mueV. In order to improve on these limits and continue the search for plausible dark-matter axions, the system was considerably upgraded from 2005 until 2008. In the upgrade, the key technical advance was the use of a dc Superconducting QUantum Interference Device (SQUID) as a microwave amplifier. The SQUID amplifier's noise level is near

Conformational changes in proteins recovered from jumbo squid (Dosidicus gigas) muscle through pH shift washing treatments.

PubMed

Cortés-Ruiz, Juan A; Pacheco-Aguilar, Ramón; Ramírez-Suárez, Juan C; Lugo-Sánchez, Maria E; García-Orozco, Karina D; Sotelo-Mundo, Rogerio R; Peña-Ramos, Aida

2016-04-01

Conformational and thermal-rheological properties of acidic (APC) and neutral (NPC) protein concentrates were evaluated and compared to those of squid (Dosidicus gigas) muscle proteins (SM). Surface hydrophobicity, sulfhydryl status, secondary structure profile, differential scanning calorimetry and oscillatory dynamic rheology were used to evaluate the effect of treatments on protein properties. Acidic condition during the washing process (APC) promoted structural and conformational changes in the protein present in the concentrate produced. These changes were enhanced during the heat setting of the corresponding sol. Results demonstrate that washing squid muscle under the proposed acidic conditions is a feasible technological alternative for squid-based surimi production improving its yield and gel-forming ability. Copyright © 2015. Published by Elsevier Ltd.

Food web and fish stock changes in central Chile: comparing the roles of jumbo squid (Dosidicus gigas) predation, the environment, and fisheries

NASA Astrophysics Data System (ADS)

Neira, Sergio; Arancibia, Hugo

2013-10-01

We analyzed recent food web and fish stock changes in the central Chile marine ecosystem, comparing the roles of jumbo squid (Dosidicus gigas) as predator, the environment, and fishing. To accomplish this we used food web modeling and the Ecopath with Ecosim software (EwE). The principal fish stocks have experienced wide decadal fluctuations in the past 30 years, including stock collapses of horse mackerel (Trachurus murphyi) and hake (Merluccius gayi), and there was a large influx of jumbo squid during the mid-2000s. We used two EwE models representing the food web off central Chile to test the hypothesis that predation by jumbo squid has been significant in explaining the dynamics of the main fishing resources and other species in the study area. Results indicate that predation by jumbo squid on fish stocks is lower than that of other predators (e.g. hake) and the fishery. Long-term fluctuations (1978-2004) in the biomass of the main fish stocks (as well as other components of the food web) seem to be related to fishing and to variation in primary production, rather than to predation by jumbo squid alone. Jumbo squid seems to play a role as predator rather than prey in the system, but its impacts are low when compared with the impacts of other predators and fishing. Therefore, we conclude that jumbo squid predation on its prey was not the primary force behind the collapse of important fish stocks off central Chile. Future efforts should be directed to better understanding factors that trigger sudden increases in jumbo squid abundance off central Chile, as well as modeling its trophic impacts.

Pulsed jet dynamics of squid hatchlings at intermediate Reynolds numbers.

PubMed

Bartol, Ian K; Krueger, Paul S; Stewart, William J; Thompson, Joseph T

2009-05-01

Squid paralarvae (hatchlings) rely predominantly on a pulsed jet for locomotion, distinguishing them from the majority of aquatic locomotors at low/intermediate Reynolds numbers (Re), which employ oscillatory/undulatory modes of propulsion. Although squid paralarvae may delineate the lower size limit of biological jet propulsion, surprisingly little is known about the hydrodynamics and propulsive efficiency of paralarval jetting within the intermediate Re realm. To better understand paralarval jet dynamics, we used digital particle image velocimetry (DPIV) and high-speed video to measure bulk vortex properties (e.g. circulation, impulse, kinetic energy) and other jet features [e.g. average and peak jet velocity along the jet centerline (U(j) and U(jmax), respectively), jet angle, jet length based on the vorticity and velocity extents (L(omega) and L(V), respectively), jet diameter based on the distance between vorticity peaks (D(omega)), maximum funnel diameter (D(F)), average and maximum swimming speed (U and U(max), respectively)] in free-swimming Doryteuthis pealeii paralarvae (1.8 mm dorsal mantle length) (Re(squid)=25-90). Squid paralarvae spent the majority of their time station holding in the water column, relying predominantly on a frequent, high-volume, vertically directed jet. During station holding, paralarvae produced a range of jet structures from spherical vortex rings (L(omega)/D(omega)=2.1, L(V)/D(F)=13.6) to more elongated vortex ring structures with no distinguishable pinch-off (L(omega)/D(omega)=4.6, L(V)/D(F)=36.0). To swim faster, paralarvae increased pulse duration and L(omega)/D(omega), leading to higher impulse but kept jet velocity relatively constant. Paralarvae produced jets with low slip, i.e. ratio of jet velocity to swimming velocity (U(j)/U or U(jmax)/U(max)), and exhibited propulsive efficiency [eta(pd)=74.9+/-8.83% (+/-s.d.) for deconvolved data] comparable with oscillatory/undulatory swimmers. As slip decreased with speed

Interannual and seasonal variability of winter-spring cohort of neon flying squid abundance in the Northwest Pacific Ocean during 1995-2011

NASA Astrophysics Data System (ADS)

Yu, Wei; Chen, Xinjun; Yi, Qian

2016-06-01

The neon flying squid, Ommastrephes bartramii, is a species of economically important cephalopod in the Northwest Pacific Ocean. Its short lifespan increases the susceptibility of the distribution and abundance to the direct impact of the environmental conditions. Based on the generalized linear model (GLM) and generalized additive model (GAM), the commercial fishery data from the Chinese squid-jigging fleets during 1995 to 2011 were used to examine the interannual and seasonal variability in the abundance of O. bartramii, and to evaluate the influences of variables on the abundance (catch per unit effort, CPUE). The results from GLM suggested that year, month, latitude, sea surface temperature (SST), mixed layer depth (MLD), and the interaction term ( SST×MLD) were significant factors. The optimal model based on GAM included all the six significant variables and could explain 42.43% of the variance in nominal CPUE. The importance of the six variables was ranked by decreasing magnitude: year, month, latitude, SST, MLD and SST×MLD. The squid was mainly distributed in the waters between 40°N and 44°N in the Northwest Pacific Ocean. The optimal ranges of SST and MLD were from 14 to 20°C and from 10 to 30 m, respectively. The squid abundance greatly fluctuated from 1995 to 2011. The CPUE was low during 1995-2002 and high during 2003-2008. Furthermore, the squid abundance was typically high in August. The interannual and seasonal variabilities in the squid abundance were associated with the variations of marine environmental conditions and the life history characteristics of squid.

76 FR 3044 - Fisheries of the Exclusive Economic Zone Off Alaska; Sculpins, Sharks, Squid, and Octopus in the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-19

..., Squid, and Octopus in the Gulf of Alaska AGENCY: National Marine Fisheries Service (NMFS), National... prohibiting directed fishing for sculpins, sharks, squid, and octopus in the Gulf of Alaska (GOA). This action..., and octopus in the GOA. DATES: Effective 1200 hrs, Alaska local time (A.l.t.), January 13, 2011...

Measurement of metallic contaminants in food with a high-Tc SQUID

NASA Astrophysics Data System (ADS)

Tanaka, Saburo; Natsume, Miyuki; Uchida, Masashi; Hotta, Naoki; Matsuda, Takemasa; Spanut, Zarina A.; Hatsukade, Yoshimi

2004-04-01

We have proposed and demonstrated a high-Tc SQUID system for detecting metallic contaminants in foodstuffs. There is a demand for the development of systems for detecting not only magnetic materials but also non-magnetic materials such as Cu and aluminium in foodstuffs to ensure food safety. The system consists of a SQUID magnetometer, an excitation coil and a permanent magnet. For a non-magnetic sample, an AC magnetic field is applied during detection to induce an eddy current in the sample. For a magnetizable sample, a strong magnetic field is applied to the sample prior to the detection attempt. We were able to detect a stainless steel ball with a diameter of 0.1 mm and a Cu ball less than 1 mm in diameter, for example.

Compatibility of photomultiplier tube operation with SQUIDs for a neutron EDM experiment

NASA Astrophysics Data System (ADS)

Libersky, Matthew; nEDM Collaboration

2013-10-01

An experiment at the Spallation Neutron Source at Oak Ridge National Laboratory with the goal of reducing the experimental limit on the electric dipole moment (EDM) of the neutron will measure the precession frequencies of neutrons when a strong electric field is applied parallel and anti-parallel to a weak magnetic field. A difference in these frequencies would indicate a nonzero neutron EDM. To correct for drifts of the magnetic field in the measurement volume, polarized 3He will be used as a co-magnetometer. In one of the two methods built into the apparatus, superconducting quantum interference devices (SQUIDs) will be used to read out the 3He magnetization. Photomultiplier tubes will be used concurrently to measure scintillation light from neutron capture by 3He. However, the simultaneous noise-sensitive magnetic field measurement by the SQUIDs makes conventional PMT operation problematic due to the alternating current involved in generating the high voltages needed. Tests were carried out at Los Alamos National Laboratory to study the compatibility of simultaneous SQUID and PMT operation, using a custom battery-powered high-voltage power supply developed by Meyer and Smith (NIM A 647.1) to operate the PMT. The results of these tests will be presented.

High-resolution imaging of magnetic fields using scanning superconducting quantum interference device (SQUID) microscopy

NASA Astrophysics Data System (ADS)

Fong de Los Santos, Luis E.

Development of a scanning superconducting quantum interference device (SQUID) microscope system with interchangeable sensor configurations for imaging magnetic fields of room-temperature (RT) samples with sub-millimeter resolution. The low-critical-temperature (Tc) niobium-based monolithic SQUID sensor is mounted in the tip of a sapphire rod and thermally anchored to the cryostat helium reservoir. A 25 mum sapphire window separates the vacuum space from the RT sample. A positioning mechanism allows adjusting the sample-to-sensor spacing from the top of the Dewar. I have achieved a sensor-to-sample spacing of 100 mum, which could be maintained for periods of up to 4 weeks. Different SQUID sensor configurations are necessary to achieve the best combination of spatial resolution and field sensitivity for a given magnetic source. For imaging thin sections of geological samples, I used a custom-designed monolithic low-Tc niobium bare SQUID sensor, with an effective diameter of 80 mum, and achieved a field sensitivity of 1.5 pT/Hz1/2 and a magnetic moment sensitivity of 5.4 x 10-18 Am2/Hz1/2 at a sensor-to-sample spacing of 100 mum in the white noise region for frequencies above 100 Hz. Imaging action currents in cardiac tissue requires higher field sensitivity, which can only be achieved by compromising spatial resolution. I developed a monolithic low-Tc niobium multiloop SQUID sensor, with sensor sizes ranging from 250 mum to 1 mm, and achieved sensitivities of 480 - 180 fT/Hz1/2 in the white noise region for frequencies above 100 Hz, respectively. For all sensor configurations, the spatial resolution was comparable to the effective diameter and limited by the sensor-to-sample spacing. Spatial registration allowed us to compare high-resolution images of magnetic fields associated with action currents and optical recordings of transmembrane potentials to study the bidomain nature of cardiac tissue or to match petrography to magnetic field maps in thin sections of

Enhanced quench propagation in 2G-HTS coils co-wound with stainless steel or anodised aluminium tapes

NASA Astrophysics Data System (ADS)

Núñez-Chico, A. B.; Martínez, E.; Angurel, L. A.; Navarro, R.

2016-08-01

Early quench detection and thermal stability of superconducting coils are of great relevance for practical applications. Magnets made with second generation high temperature superconducting (2G-HTS) tapes present low quench propagation velocities and therefore slow voltage development and high local temperature rises, which may cause irreversible damage. Since quench propagation depends on the anisotropy of the thermal conductivity, this may be used to achieve an improvement of the thermal stability and robustness of 2G-HTS coils. On pancake type coils, the thermal conductivity along the tapes (coil’s azimuthal direction) is mostly fixed by the 2G-HTS tape characteristics, so that the reduction of anisotropy relies on the improvement of the radial thermal conductivity, which depends on the used materials between superconducting tapes, as well as on the winding and impregnation processes. In this contribution, we have explored two possibilities for such anisotropy reduction: by using anodised aluminium or stainless steel tapes co-wound with the 2G-HTS tapes. For all the analysed coils, critical current distribution, minimum quench energy values and both tangential and radial quench propagation velocities at different temperatures and currents are reported and compared with the results of similar coils co-wound with polyimide (Kapton®) tapes.

Comprehensive comparison of the levitation performance of bulk YBaCuO arrays above two different types of magnetic guideways

NASA Astrophysics Data System (ADS)

Deng, Zigang; Qian, Nan; Che, Tong; Jin, Liwei; Si, Shuaishuai; Zhang, Ya; Zheng, Jun

2016-12-01

The permanent magnet guideway (PMG) is an important part of high temperature superconducting (HTS) maglev systems. So far, two types of PMG, the normal PMG and Halbach-type PMG, are widely applied in present maglev transportation systems. In this paper, the levitation performance of high temperature superconductor bulks above the two PMGs was synthetically compared. Both static levitation performance and dynamic response characteristics were investigated. Benefiting from the reasonable magnetic field distribution, the Halbach-type PMG is able to gain larger levitation force, greater levitation force decay during the same relaxation time, bigger resonance frequency and dynamic stiffness for the bulk superconductor levitation unit compared with the normal PMG. Another finding is that the Halbach-type PMG is not sensitive to the levitation performance of the bulk levitation unit with different arrays. These results are helpful for the practical application of HTS maglev systems.

Experience of 12 kA / 16 V SMPS during the HTS Current Leads Test

NASA Astrophysics Data System (ADS)

Panchal, P.; Christian, D.; Panchal, R.; Sonara, D.; Purwar, G.; Garg, A.; Nimavat, H.; Singh, G.; Patel, J.; Tanna, V.; Pradhan, S.

2017-04-01

As a part of up gradation plans in SST-1 Tokamak, one pair of 3.3 kA rated prototype hybrid current leads were developed using Di-BSCCO as High Temperature Superconductors (HTS) and the copper heat exchanger. In order to validate the manufacturing procedure prior to go for series production of such current leads, it was recommended to test these current leads using dedicated and very reliable DC switch mode power supply (SMPS). As part of test facility, 12 kA, 16 VDC programmable SMPS was successfully installed, commissioned and tested. This power supply has special features such as modularity, N+1 redundancy, very low ripple voltage, precise current measurements with Direct Current Current Transformer, CC/CV modes with auto-crossover and auto-sequence programming. As a part of acceptance of this converter, A 5.8 mΩ water-cooled resistive dummy load and PLC based SCADA system is designed, developed for commissioning of power supply. The same power supply was used for the testing of the prototype HTS current leads. The paper describes the salient features and experience of state-of-art of power supply and results obtained from this converter during the HTS current leads test.

Nanomaterial (NM) bioactivity profiling by ToxCast high-throughput screening (HTS)

EPA Science Inventory

Rapidly increasing numbers of new NMs and their uses demand efficient tests of NM bioactivity for safety assessment. The EPA’s ToxCast program uses HTS assays to prioritize for targeted testing, identify biological pathways affected, and aid in linking NM properties and potential...

Levitation or suspension: Which one is better for the heavy-load HTS maglev transportation

NASA Astrophysics Data System (ADS)

Liu, Wei; Kang, Dong; Yang, X. F.; Wang, Fei; Peng, G. H.; Zheng, Jun; Ma, G. T.; Wang, J. S.

2015-09-01

Because of the limitation of permanent magnet (PM), the efficient of bulk high-Tc superconductor (HTSC) in a high-Tc superconducting (HTS) maglev system is not very high. It is better to magnetize the bulk HTSC with a high trapped field to increase the force density. The different application type of magnetized bulk HTSC in a maglev system, namely, levitation or suspension type, will bring quite different operation performance. This paper discusses the influence of application type on operation performance of magnetized bulk HTSC by experiments and simulations. From the discussion, it can be found which application type is better for the heavy-load HTS maglev system.

SQUIDs vs. Induction Coils for Ultra-Low Field Nuclear Magnetic Resonance: Experimental and Simulation Comparison

PubMed Central

Matlashov, Andrei N.; Schultz, Larry J.; Espy, Michelle A.; Kraus, Robert H.; Savukov, Igor M.; Volegov, Petr L.; Wurden, Caroline J.

2011-01-01

Nuclear magnetic resonance (NMR) is widely used in medicine, chemistry and industry. One application area is magnetic resonance imaging (MRI). Recently it has become possible to perform NMR and MRI in the ultra-low field (ULF) regime requiring measurement field strengths of the order of only 1 Gauss. This technique exploits the advantages offered by superconducting quantum interference devices or SQUIDs. Our group has built SQUID based MRI systems for brain imaging and for liquid explosives detection at airport security checkpoints. The requirement for liquid helium cooling limits potential applications of ULF MRI for liquid identification and security purposes. Our experimental comparative investigation shows that room temperature inductive magnetometers may provide enough sensitivity in the 3–10 kHz range and can be used for fast liquid explosives detection based on ULF NMR technique. We describe experimental and computer-simulation results comparing multichannel SQUID based and induction coils based instruments that are capable of performing ULF MRI for liquid identification. PMID:21747638

Cryogenic experiences during W7-X HTS-current lead tests

DOE Office of Scientific and Technical Information (OSTI.GOV)

Richter, Thomas; Lietzow, Ralph

2014-01-29

The Karlsruhe Institute of Technology (KIT) was responsible for design, production and test of the High Temperature Superconductor (HTS) current leads (CL) for the stellerator Wendelstein 7-X (W7-X). 16 current leads were delivered. Detailed prototype tests as well as the final acceptance tests were performed at KIT, using a dedicated test cryostat assembled beside and connected to the main vacuum vessel of the TOSKA facility. A unique feature is the upside down orientation of the current leads due to the location of the power supplies in the basement of the experimental area of W7-X. The HTS-CL consists of three mainmore » parts: the cold end for the connection to the bus bar at 4.5 K, the HTS part operating in the temperature range from 4.5 K to 65 K and a copper heat exchanger (HEX) in the temperature range from 65 K to room temperature, which is cooled with 50 K helium. Therefore in TOSKA it is possible to cool test specimens simultaneously with helium at two different temperature levels. The current lead tests included different scenarios with currents up to 18.2 kA. In total, 10 cryogenic test campaigns with a total time of about 24 weeks were performed till beginning of 2013. The test facility as well as the 2 kW cryogenic plant of ITEP showed a very good reliability. However, during such a long and complex experimental campaign, one has to deal with failures, technical difficulties and incidents. The paper gives a summary of the test performance comprising the test preparation and operation. This includes the performance and reliability of the refrigerator and the test facility with reference to the process measuring and control system, the data acquisition system, as well as the building infrastructure.« less

Infrared-Bolometer Arrays with Reflective Backshorts

NASA Technical Reports Server (NTRS)

Miller, Timothy M.; Abrahams, John; Allen, Christine A.

2011-01-01

Integrated circuits that incorporate square arrays of superconducting-transition- edge bolometers with optically reflective backshorts are being developed for use in image sensors in the spectral range from far infrared to millimeter wavelengths. To maximize the optical efficiency (and, thus, sensitivity) of such a sensor at a specific wavelength, resonant optical structures are created by placing the backshorts at a quarter wavelength behind the bolometer plane. The bolometer and backshort arrays are fabricated separately, then integrated to form a single unit denoted a backshort-under-grid (BUG) bolometer array. In a subsequent fabrication step, the BUG bolometer array is connected, by use of single-sided indium bump bonding, to a readout device that comprises mostly a superconducting quantum interference device (SQUID) multiplexer circuit. The resulting sensor unit comprising the BUG bolometer array and the readout device is operated at a temperature below 1 K. The concept of increasing optical efficiency by use of backshorts at a quarter wavelength behind the bolometers is not new. Instead, the novelty of the present development lies mainly in several features of the design of the BUG bolometer array and the fabrication sequence used to implement the design. Prior to joining with the backshort array, the bolometer array comprises, more specifically, a square grid of free-standing molybdenum/gold superconducting-transition-edge bolometer elements on a 1.4- m-thick top layer of silicon that is part of a silicon support frame made from a silicon-on-insulator wafer. The backshort array is fabricated separately as a frame structure that includes support beams and contains a correspond - ing grid of optically reflective patches on a single-crystal silicon substrate. The process used to fabricate the bolometer array includes standard patterning and etching steps that result in the formation of deep notches in the silicon support frame. These notches are designed to

The Polarbear-2 and the Simons Array experiments

DOE PAGES

Suzuki, A.; Ade, P.; Akiba, Y.; ...

2016-01-06

Here, we present an overview of the design and status of the POLARBEAR-2 and the Simons Array experiments. POLARBEAR- 2 is a Cosmic Microwave Background polarimetry experiment which aims to characterize the arc-minute angular scale B-mode signal from weak gravitational lensing and search for the degree angular scale B-mode signal from inflationary gravitational waves. The receiver has a 365 mm diameter focal plane cooled to 270 milli-Kelvin. The focal plane is filled with 7,588 dichroic lenslet-antenna coupled polarization sensitive Transition Edge Sensor (TES) bolometric pixels that are sensitive to 95 GHz and 150 GHz bands simultaneously. The TES bolometers aremore » read-out by SQUIDs with 40 channel frequency domain multiplexing. Refractive optical elements are made with high purity alumina to achieve high optical throughput. The receiver is designed to achieve noise equivalent temperature of 5.8 µK CMB√s in each frequency band. POLARBEAR-2 will deploy in 2016 in the Atacama desert in Chile. The Simons Array is a project to further increase sensitivity by deploying three POLARBEAR-2 type receivers. The Simons Array will cover 95 GHz, 150 GHz and 220 GHz frequency bands for foreground control. The Simons Array will be able to constrain tensor-to-scalar ratio and sum of neutrino masses to σ(r) = 6×10 $-$3 at r = 0.1 and Σm ν(σ = 1) to 40 meV.« less

The Development and Demonstration of a 360m/10 kA HTS DC Power Cable

NASA Astrophysics Data System (ADS)

Xiao, Liye

With the quick development of renewable energy, it is expected that the electric power from renewable energy would be the dominant one for the future power grid. Due to the specialty of the renewable energy, the HVDC power transmission would be very useful for the transmission of electric power from renewable energy. DC power cable made of High Tc Superconductor (HTS) would be a possible alternative for the construction of HVDC power transmission system. In this chapter, we report the development and demonstration of a 360 m/10 kA HTS DC power cable and the test results.

Analysis of the tenderisation of jumbo squid (Dosidicus gigas) meat by ultrasonic treatment using response surface methodology.

PubMed

Hu, Yaqin; Yu, Hiaxia; Dong, Kaicheng; Yang, Shuibing; Ye, Xingqian; Chen, Shiguo

2014-10-01

Due to its unique structure, jumbo squid (Dosidicus gigas) meat is sensitive to heat treatment, which makes the traditional squid products taste tough and hard. This study aimed to tenderise jumbo squid meat through ultrasonic treatment. Response surface methodology (RSM) was used to predict the tenderising effect of various treatment conditions. According to the results of RSM, the optimal conditions appeared to be a power of 186.9 W, a frequency of 25.6 kHz, and a time of 30.8 min, and the predicted values of flexibility and firmness under these optimal conditions were 2.40 mm and 435.1 g, respectively. Protein degradation and a broken muscle fibre structure were observed through histological assay and SDS-PAGE, which suggests a satisfactory tenderisation effect. Copyright © 2014. Published by Elsevier Ltd.

Ontogenetic and Experience-Dependent Changes in Defensive Behavior in Captive-Bred Hawaiian Bobtail Squid, Euprymna scolopes

PubMed Central

Seehafer, Kia; Brophy, Samantha; Tom, Sara R.; Crook, Robyn J.

2018-01-01

Cephalopod molluscs are known for their extensive behavioral repertoire and their impressive learning abilities. Their primary defensive behaviors, such as camouflage, have received detailed study, but knowledge is limited to intensive study of relatively few species. A considerable challenge facing cephalopod research is the need to establish new models that can be captive bred, are tractable for range of different experimental procedures, and that will address broad questions in biological research. The Hawaiian Bobtail Squid (Euprymna scolopes) is a small, tropical cephalopod that has a long history of research in the field of microbial symbiosis, but offers great promise as a novel behavioral and neurobiological model. It can be bred in the laboratory through multiple generations, one of the few species of cephalopod that can meet this requirement (which is incorporated in regulations such as EU directive 2010/63/EU). Additionally, laboratory culture makes E. scolopes an ideal model for studying ontogeny- and experience-dependent behaviors. In this study, we show that captive bred juvenile and adult E. scolopes produce robust, repeatable defensive behaviors when placed in an exposed environment and presented with a visual threat. Further, adult and juvenile squid employ different innate defensive behaviors when presented with a size-matched model predator. When a 10-min training procedure was repeated over three consecutive days, defensive behaviors habituated in juvenile squid for at least 5 days after training, but memory did not appear to persist for 14 days. In contrast, adult squid did not show any evidence of long-term habituation memory. Thus we conclude that this species produces a range of quantifiable, modifiable behaviors even in a laboratory environment where ecologically-relevant, complex behavioral sequences may not reliably occur. We suggest that the lack of long-term memory in adult squid may be related to their less escalated initial response

A high-sensitivity magnetocardiography system with a divided gradiometer array inside a low boil-off Dewar

NASA Astrophysics Data System (ADS)

Lee, Y. H.; Yu, K. K.; Kim, J. M.; Kwon, H.; Kim, K.

2009-11-01

We fabricated a low-noise 64-channel first-order axial gradiometer system for measuring magnetocardiography (MCG) signals. The key technical features of the system are the compact structure of the gradiometer, division of the sensor array plate, direct mounting of the sensor plates into the Dewar bottom, reduced neck diameter of the liquid He Dewar, and compact readout electronics. To make the refill interval of liquid He longer, the distance between the compensation coil of the gradiometer and the input coil pads of the superconducting quantum interference device (SQUID) was reduced to 20 mm. By using direct ultrasonic bonding of Nb wires between the pickup coil wires and input coil pads, the superconductive connection structure became simple. The baseline of the first-order gradiometer is 70 mm, a little longer than for typical conventional axial gradiometers, to provide a larger signal amplitude for deep sources. The 64-channel gradiometer array consists of four blocks, and each block is fixed separately onto the bottom of the Dewar. The neck diameter of the He Dewar (192 mm) is smaller than the bottom diameter (280 mm) in which the gradiometers are distributed. The average boil-off rate of the Dewar is 3 l per day when the 64-channel system is in operation every day. Double relaxation oscillation SQUIDs (DROSs) having large flux-to-voltage transfer coefficients were used to operate SQUIDs via compact electronics. The magnetically shielded room (MSR) has a wall thickness of 80 mm, and consists of two layers of permalloy and one layer of aluminum. When the 64-channel system was installed inside the MSR, the field noise level of the system was about 3.5 fTrms Hz-1/2 at 100 Hz. MCG measurements with high signal quality were done successfully using the developed system. In addition to the parameter analysis method, we developed software for the three-dimensional imaging of the myocardial current on a realistic image of the heart based on the anatomical image of the

Transcriptome analysis of Nautilus and pygmy squid developing eye provides insights in lens and eye evolution.

PubMed

Sousounis, Konstantinos; Ogura, Atsushi; Tsonis, Panagiotis A

2013-01-01

Coleoid cephalopods like squids have a camera-type eye similar to vertebrates. On the other hand, Nautilus (Nautiloids) has a pinhole eye that lacks lens and cornea. Since pygmy squid and Nautilus are closely related species they are excellent model organisms to study eye evolution. Having being able to collect Nautilus embryos, we employed next-generation RNA sequencing using Nautilus and pygmy squid developing eyes. Their transcriptomes were compared and analyzed. Enrichment analysis of Gene Ontology revealed that contigs related to nucleic acid binding were largely up-regulated in squid, while the ones related to metabolic processes and extracellular matrix-related genes were up-regulated in Nautilus. These differences are most likely correlated with the complexity of tissue organization in these species. Moreover, when the analysis focused on the eye-related contigs several interesting patterns emerged. First, contigs from both species related to eye tissue differentiation and morphogenesis as well as to cilia showed best hits with their Human counterparts, while contigs related to rabdomeric photoreceptors showed the best hit with their Drosophila counterparts. This bolsters the idea that eye morphogenesis genes have been generally conserved in evolution, and compliments other studies showing that genes involved in photoreceptor differentiation clearly follow the diversification of invertebrate (rabdomeric) and vertebrate (ciliated) photoreceptors. Interestingly some contigs showed as good a hit with Drosophila and Human homologues in Nautilus and squid samples. One of them, capt/CAP1, is known to be preferentially expressed in Drosophila developing eye and in vertebrate lens. Importantly our analysis also provided evidence of gene duplication and diversification of their function in both species. One of these genes is the Neurofibromatosis 1 (NF1/Nf1), which in mice has been implicated in lens formation, suggesting a hitherto unsuspected role in the evolution

Transcriptome Analysis of Nautilus and Pygmy Squid Developing Eye Provides Insights in Lens and Eye Evolution

PubMed Central

Sousounis, Konstantinos; Ogura, Atsushi; Tsonis, Panagiotis A.

2013-01-01

Coleoid cephalopods like squids have a camera-type eye similar to vertebrates. On the other hand, Nautilus (Nautiloids) has a pinhole eye that lacks lens and cornea. Since pygmy squid and Nautilus are closely related species they are excellent model organisms to study eye evolution. Having being able to collect Nautilus embryos, we employed next-generation RNA sequencing using Nautilus and pygmy squid developing eyes. Their transcriptomes were compared and analyzed. Enrichment analysis of Gene Ontology revealed that contigs related to nucleic acid binding were largely up-regulated in squid, while the ones related to metabolic processes and extracellular matrix-related genes were up-regulated in Nautilus. These differences are most likely correlated with the complexity of tissue organization in these species. Moreover, when the analysis focused on the eye-related contigs several interesting patterns emerged. First, contigs from both species related to eye tissue differentiation and morphogenesis as well as to cilia showed best hits with their Human counterparts, while contigs related to rabdomeric photoreceptors showed the best hit with their Drosophila counterparts. This bolsters the idea that eye morphogenesis genes have been generally conserved in evolution, and compliments other studies showing that genes involved in photoreceptor differentiation clearly follow the diversification of invertebrate (rabdomeric) and vertebrate (ciliated) photoreceptors. Interestingly some contigs showed as good a hit with Drosophila and Human homologues in Nautilus and squid samples. One of them, capt/CAP1, is known to be preferentially expressed in Drosophila developing eye and in vertebrate lens. Importantly our analysis also provided evidence of gene duplication and diversification of their function in both species. One of these genes is the Neurofibromatosis 1 (NF1/Nf1), which in mice has been implicated in lens formation, suggesting a hitherto unsuspected role in the evolution

Study on stabilization and quench protection of coils wound of HTS coated conductors considering quench origins - Proposal of criteria for stabilization and quench protection

NASA Astrophysics Data System (ADS)

Tsukamoto, Osami; Fujimoto, Yasutaka; Takao, Tomoaki

2014-09-01

It has been considered that HTS coils are hard to be quenched because of high quench energy due to high critical temperature and high specific heat of HTS wires. Therefore, attention to quench protection was not much paid. However, HTS coils still have possibility to be quenched during operation by mainly the following two origins, (a) presence of non-recoverable local defects in the conductors and (b) temperature rise of long part of the conductor. Actually, severe quench accidents, such as burning coils, are occurring in various places as scales of HTS increased. Purposes of this paper are to study on behaviors of normal zone and hot spot temperature of wires during quench detect/energy dump sequence and to find criteria for the stability and quench protection. In the paper, criteria are proposed for stability and quench protection of HTS coils. A criterion for the stability is that a coil can be operated stably without a quench against defects in coil windings and that for quench protection is that a coil can be safely protected from damages caused by a quench due to temperature rise of long part of coil wires. The criteria are used as design rules for HTS coils.

Squid-based CW NMR system for measuring the magnetization of helium-3 films

NASA Astrophysics Data System (ADS)

White, Kevin Spencer

This thesis describes the design and construction of a SQUID-based CW NMR system together with its application in a study of the two dimensional magnetism of 3He. 3He provides an exemplary system for the study of two-dimensional magnetism. Two-dimensional 3He films of varying coverages may be formed by plating 3He on relatively uniform two-dimensional substrates, such as GTA Grafoil and ZYX graphite substrates. At coverages above approximately 20 atoms/nm. 2 on these substrates, the second layer of 3He exhibits a strong ferromagnetic ordering tendency. The ferromagnetic ordering presents as a rapid onset of measured magnetization that becomes independent of the applied magnetic field as film temperatures approach 1 mK. Very low applied magnetic fields are used to probe the ferromagnetic ordering in order to minimize masking of the measured magnetization and to stay within the available bandwidth of the SQUID. Commensurate with the ferromagnetic ordering, the NMR linewidth increases dramatically at these coverages and temperatures. An increasing linewidth equates to a short decay time with respect to pulsed NMR probing of the two-dimensional 3He magnetization. The decay times at these coverages and temperatures become so short that they fall below the minimum recovery time necessary for a SQUID-based pulsed NMR system to recover from the relatively large tipping pulse and acquire meaningful data. To address this problem, we have designed a SQUID-based CW NMR system to leverage as much of an already-existing pulsed NMR system as possible but allow accurate measurement of the rapid onset of ferromagnetic ordering of the 3He films below the approximate 1 mK temperature limit of the pulsed NMR system.

An HTS-compatible 3D colony formation assay to identify tumor-specific chemotherapeutics.

PubMed

Horman, Shane R; To, Jeremy; Orth, Anthony P

2013-12-01

There has been increasing interest in the development of cellular behavior models that take advantage of three-dimensional (3D) cell culture. To enable assessment of differential perturbagen impacts on cell growth in 2D and 3D, we have miniaturized and adapted for high-throughput screening (HTS) the soft agar colony formation assay, employing a laser-scanning cytometer to image and quantify multiple cell types simultaneously. The assay is HTS compatible, providing high-quality, image-based, replicable data for multiple, co-cultured cell types. As proof of concept, we subjected colorectal carcinoma colonies in 3D soft agar to a mini screen of 1528 natural product compounds. Hit compounds from the primary screen were rescreened in an HTS 3D co-culture matrix containing colon stromal cells and cancer cells. By combining tumor cells and normal, nontransformed colon epithelial cells in one primary screening assay, we were able to obtain differential IC50 data, thereby distinguishing tumor-specific compounds from general cytotoxic compounds. Moreover, we were able to identify compounds that antagonized tumor colony formation in 3D only, highlighting the importance of this assay in identifying agents that interfere with 3D tumor structural growth. This screening platform provides a fast, simple, and robust method for identification of tumor-specific agents in a biologically relevant microenvironment.

Neural control of tuneable skin iridescence in squid

PubMed Central

Wardill, T. J.; Gonzalez-Bellido, P. T.; Crook, R. J.; Hanlon, R. T.

2012-01-01

Fast dynamic control of skin coloration is rare in the animal kingdom, whether it be pigmentary or structural. Iridescent structural coloration results when nanoscale structures disrupt incident light and selectively reflect specific colours. Unlike animals with fixed iridescent coloration (e.g. butterflies), squid iridophores (i.e. aggregations of iridescent cells in the skin) produce dynamically tuneable structural coloration, as exogenous application of acetylcholine (ACh) changes the colour and brightness output. Previous efforts to stimulate iridophores neurally or to identify the source of endogenous ACh were unsuccessful, leaving researchers to question the activation mechanism. We developed a novel neurophysiological preparation in the squid Doryteuthis pealeii and demonstrated that electrical stimulation of neurons in the skin shifts the spectral peak of the reflected light to shorter wavelengths (greater than 145 nm) and increases the peak reflectance (greater than 245%) of innervated iridophores. We show ACh is released within the iridophore layer and that extensive nerve branching is seen within the iridophore. The dynamic colour shift is significantly faster (17 s) than the peak reflectance increase (32 s), revealing two distinct mechanisms. Responses from a structurally altered preparation indicate that the reflectin protein condensation mechanism explains peak reflectance change, while an undiscovered mechanism causes the fast colour shift. PMID:22896651

Ultra-low field MRI food inspection system prototype

NASA Astrophysics Data System (ADS)

Kawagoe, Satoshi; Toyota, Hirotomo; Hatta, Junichi; Ariyoshi, Seiichiro; Tanaka, Saburo

2016-11-01

We develop an ultra-low field (ULF) magnetic resonance imaging (MRI) system using a high-temperature superconducting quantum interference device (HTS-SQUID) for food inspection. A two-dimensional (2D)-MR image is reconstructed from the grid processing raw data using the 2D fast Fourier transform method. In a previous study, we combined an LC resonator with the ULF-MRI system to improve the detection area of the HTS-SQUID. The sensitivity was improved, but since the experiments were performed in a semi-open magnetically shielded room (MSR), external noise was a problem. In this study, we develop a compact magnetically shielded box (CMSB), which has a small open window for transfer of a pre-polarized sample. Experiments were performed in the CMSB and 2D-MR images were compared with images taken in the semi-open MSR. A clear image of a disk-shaped water sample is obtained, with an outer dimension closer to that of the real sample than in the image taken in the semi-open MSR. Furthermore, the 2D-MR image of a multiple cell water sample is clearly reconstructed. These results show the applicability of the ULF-MRI system in food inspection.

Magnet design with 100-kA HTS STARS conductors for the helical fusion reactor

NASA Astrophysics Data System (ADS)

Yanagi, N.; Terazaki, Y.; Ito, S.; Tamura, H.; Hamaguchi, S.; Mito, T.; Hashizume, H.; Sagara, A.

2016-12-01

The high-temperature superconducting (HTS) option is employed for the conceptual design of the LHD-type helical fusion reactor FFHR-d1. The 100-kA-class STARS (Stacked Tapes Assembled in Rigid Structure) conductor is used for the magnet system including the continuously wound helical coils. Protection of the magnet system in case of a quench is a crucial issue and the hot-spot temperature during an emergency discharge is estimated based on the zero-dimensional and one-dimensional analyses. The number of division of the coil winding package is examined to limit the voltage generation. For cooling the HTS magnet, helium gas flow is considered and its feasibility is examined by simple analysis as a first step.

An accurate bacterial DNA quantification assay for HTS library preparation of human biological samples.

PubMed

Seashols-Williams, Sarah; Green, Raquel; Wohlfahrt, Denise; Brand, Angela; Tan-Torres, Antonio Limjuco; Nogales, Francy; Brooks, J Paul; Singh, Baneshwar

2018-05-17

Sequencing and classification of microbial taxa within forensically relevant biological fluids has the potential for applications in the forensic science and biomedical fields. The quantity of bacterial DNA from human samples is currently estimated based on quantity of total DNA isolated. This method can miscalculate bacterial DNA quantity due to the mixed nature of the sample, and consequently library preparation is often unreliable. We developed an assay that can accurately and specifically quantify bacterial DNA within a mixed sample for reliable 16S ribosomal DNA (16S rDNA) library preparation and high throughput sequencing (HTS). A qPCR method was optimized using universal 16S rDNA primers, and a commercially available bacterial community DNA standard was used to develop a precise standard curve. Following qPCR optimization, 16S rDNA libraries from saliva, vaginal and menstrual secretions, urine, and fecal matter were amplified and evaluated at various DNA concentrations; successful HTS data were generated with as low as 20 pg of bacterial DNA. Changes in bacterial DNA quantity did not impact observed relative abundances of major bacterial taxa, but relative abundance changes of minor taxa were observed. Accurate quantification of microbial DNA resulted in consistent, successful library preparations for HTS analysis. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Scanning SQUID microscope with an in-situ magnetization/demagnetization field for geological samples

NASA Astrophysics Data System (ADS)

Du, Junwei; Liu, Xiaohong; Qin, Huafeng; Wei, Zhao; Kong, Xiangyang; Liu, Qingsong; Song, Tao

2018-04-01

Magnetic properties of rocks are crucial for paleo-, rock-, environmental-magnetism, and magnetic material sciences. Conventional rock magnetometers deal with bulk properties of samples, whereas scanning microscope can map the distribution of remanent magnetization. In this study, a new scanning microscope based on a low-temperature DC superconducting quantum interference device (SQUID) equipped with an in-situ magnetization/demagnetization device was developed. To realize the combination of sensitive instrument as SQUID with high magnetizing/demagnetizing fields, the pick-up coil, the magnetization/demagnetization coils and the measurement mode of the system were optimized. The new microscope has a field sensitivity of 250 pT/√Hz at a coil-to-sample spacing of ∼350 μm, and high magnetization (0-1 T)/ demagnetization (0-300 mT, 400 Hz) functions. With this microscope, isothermal remanent magnetization (IRM) acquisition and the according alternating field (AF) demagnetization curves can be obtained for each point without transferring samples between different procedures, which could result in position deviation, waste of time, and other interferences. The newly-designed SQUID microscope, thus, can be used to investigate the rock magnetic properties of samples at a micro-area scale, and has a great potential to be an efficient tool in paleomagnetism, rock magnetism, and magnetic material studies.

Age, maturation, and population structure of the Humboldt squid Dosidicus gigas off the Peruvian Exclusive Economic Zones

NASA Astrophysics Data System (ADS)

Liu, Bilin; Chen, Xinjun; Chen, Yong; Tian, Siquan; Li, Jianhua; Fang, Zhou; Yang, Mingxia

2013-01-01

Age, maturation and population structure of the Humboldt squid Dosidicus gigas were studied based on random sampling of the Chinese jigging fishery off the Peruvian Exclusive Economic Zones (EEZ) during 2008-2010. Estimated ages ranged from 144 to 633 days, confirming that the squid is a short-lived species with longevity no longer than 2 years. Occurrence of mature females and hatching in each month indicated that Humboldt squid spawned year-round. Back-calculated hatching dates for the samples were from January 22nd, 2008 to April 22nd, 2010 with a peak between January and March. Two size-based and two hatching date-based populations could be defined from mantle length (ML) at maturity and back-calculated hatching dates, respectively. Females matured at a larger size than males, and there was a significant difference in ML at maturity between the two hatching groups ( P <0.05). The waters adjacent to 11°S off the Peruvian EEZ may be a potential spawning ground. This study shows the complexity of the population structure and large variability in key life history parameters in the Humboldt squid off the Peruvian EEZ, which should be considered in the assessment and management of this important resource.

Extra Double-stranded RNA Binding Domain (dsRBD) in a Squid RNA Editing Enzyme Confers Resistance to High Salt Environment*

PubMed Central

Palavicini, Juan Pablo; Correa-Rojas, Rodrigo A.; Rosenthal, Joshua J. C.

2012-01-01

A-to-I RNA editing is particularly common in coding regions of squid mRNAs. Previously, we isolated a squid editing enzyme (sqADAR2) that shows a unique structural feature when compared with other ADAR2 family members: an additional double-stranded RNA (dsRNA) binding domain (dsRBD). Alternative splicing includes or excludes this motif, generating a novel or a conventional variant termed sqADAR2a and sqADAR2b, respectively. The extra dsRBD of sqADAR2a increases its editing activity in vitro. We hypothesized that the high activity is due to an increase in the affinity of the enzyme for dsRNA. This may be important because protein-RNA interactions can be influenced by physical factors. We became particularly interested in analyzing the effects of salt on interactions between sqADAR2 and RNA because squid cells have a ∼3-fold higher ionic strength and proportionally more Cl− than vertebrate cells. To date, in vitro biochemical analyses of adenosine deamination have been conducted using vertebrate-like ionic strength buffers containing chloride as the major anion, although the vast majority of cellular anions are known to be organic. We found that squid-like salt conditions severely impair the binding affinity of conventional ADAR2s for dsRNA, leading to a decrease in nonspecific and site-specific editing activity. Inhibition of editing was mostly due to high Cl− levels and not to the high concentrations of K+, Na+, and organic anions like glutamate. Interestingly, the extra dsRBD in sqADAR2a conferred resistance to the high Cl− levels found in squid neurons. It does so by increasing the affinity of sqADAR2 for dsRNA by 30- or 100-fold in vertebrate-like or squid-like conditions, respectively. Site-directed mutagenesis of squid ADAR2a showed that its increased affinity and editing activity are directly attributable to the RNA binding activity of the extra dsRBD. PMID:22457361

HTS-DB: an online resource to publish and query data from functional genomics high-throughput siRNA screening projects.

PubMed

Saunders, Rebecca E; Instrell, Rachael; Rispoli, Rossella; Jiang, Ming; Howell, Michael

2013-01-01

High-throughput screening (HTS) uses technologies such as RNA interference to generate loss-of-function phenotypes on a genomic scale. As these technologies become more popular, many research institutes have established core facilities of expertise to deal with the challenges of large-scale HTS experiments. As the efforts of core facility screening projects come to fruition, focus has shifted towards managing the results of these experiments and making them available in a useful format that can be further mined for phenotypic discovery. The HTS-DB database provides a public view of data from screening projects undertaken by the HTS core facility at the CRUK London Research Institute. All projects and screens are described with comprehensive assay protocols, and datasets are provided with complete descriptions of analysis techniques. This format allows users to browse and search data from large-scale studies in an informative and intuitive way. It also provides a repository for additional measurements obtained from screens that were not the focus of the project, such as cell viability, and groups these data so that it can provide a gene-centric summary across several different cell lines and conditions. All datasets from our screens that can be made available can be viewed interactively and mined for further hit lists. We believe that in this format, the database provides researchers with rapid access to results of large-scale experiments that might facilitate their understanding of genes/compounds identified in their own research. DATABASE URL: http://hts.cancerresearchuk.org/db/public.

Sensory acceptability of squid rings gamma irradiated for shelf-life extension

NASA Astrophysics Data System (ADS)

Tomac, Alejandra; Cova, María C.; Narvaiz, Patricia; Yeannes, María I.

2017-01-01

The feasibility of extending the shelf-life of a squid product by gamma irradiation was analyzed. Illex argentinus rings were irradiated at 4 and 8 kGy; and stored at 4±1 °C during 77 days. No mesophilic bacteria, enterobacteriaceae and coliforms were detected in irradiated rings during storage. Psychrotrophic bacteria were significantly reduced by irradiation; their counts were fitted to a growth model which was further used for shelf-life estimations: 3 and 27 days for 0 and 4 kGy, respectively. Initially, non-irradiated as well as irradiated rings had very good sensory scores. The overall acceptability of 4 and 8 kGy rings did not decrease during 27 and 64 days, respectively, while control samples spoiled after 3 days. A radiation dose range for squid rings preservation was defined, which attained the technological shelf-life extension objective, without impairing sensory quality.

Hypoxia tolerance and antioxidant defense system of juvenile jumbo squids in oxygen minimum zones

NASA Astrophysics Data System (ADS)

Trübenbach, Katja; Teixeira, Tatiana; Diniz, Mário; Rosa, Rui

2013-10-01

Jumbo squid (Dosidicus gigas) is a large oceanic squid endemic off the Eastern Tropical Pacific that undertakes diel vertical migrations into mesopelagic oxygen minimum zones. One of the expected physiological effects of such migration is the generation of reactive oxygen species (ROS) at the surface, promoted by the transition between hypoxia and reoxygenation states. The aim of this study was to investigate the energy expenditure rates and the antioxidant stress strategies of juvenile D. gigas under normoxia and hypoxia, namely by quantifying oxygen consumption rates, antioxidant enzyme activities [including superoxide dismutase (SOD), catalase (CAT) and glutathione-S-transferase (GST)], heat shock protein expression (Hsp70/Hsc70), and lipid peroxidation [malondialdehyde (MDA) levels]. A high significant decrease (68%) in squid's metabolic rates was observed during hypoxia (p<0.05). This process of metabolic suppression was followed by a significant increase in Hsp70/Hsc70 expression (p<0.05), which may be interpreted as a strategy to prevent post-hypoxic oxidative damage during the squid's night upwards migration to the surface ocean. On the other hand, in normoxia, the higher SOD and CAT activities seemed to be a strategy to cope with the reoxygenation process, and may constitute an integrated stress response at shallower depths. GST activity and MDA concentrations did not change significantly from normoxia to hypoxia (p>0.05), with the latter indicating no enhancement of lipid peroxidation (i.e. cellular damage) at the warmer and normoxic surface waters. The understanding of such physiological strategies that are linked to oxygen deprivation and reoxygenation phases may provide valuable information about how this species is quickly responding to the impacts of environmental stressors coupled with global climate change.

Design and development of 500 m long HTS cable system in the KEPCO power grid, Korea

NASA Astrophysics Data System (ADS)

Sohn, S. H.; Lim, J. H.; Yang, B. M.; Lee, S. K.; Jang, H. M.; Kim, Y. H.; Yang, H. S.; Kim, D. L.; Kim, H. R.; Yim, S. W.; Won, Y. J.; Hwang, S. D.

2010-11-01

In Korea, two long-term field demonstrations for high temperature superconducting (HTS) cable have been carried out for several years; Korea Electric Power Corporation (KEPCO) and LS Cable Ltd. (LSC) independently. Encouraged at the result of the projects performed in parallel, a new project targeting the real grid operation was launched in the fourth quarter of 2008 with the Korean government's financial support. KEPCO and LSC are jointly collaborating in the selection of substation, determination of cable specification, design of cryogenic system, and the scheme of protection coordination. A three phase 500 m long HTS cable at a distribution level voltage of 22.9 kV is to be built at 154/22.9 kV Icheon substation located in near Seoul. A hybrid cryogenic system reflecting the contingency plan is being designed including cryocoolers. The HTS cable system will be installed in the second quarter of 2010, being commissioned by the fall of 2010. This paper describes the objectives of the project and design issues of the cable and cryogenic system in detail.

Cross-correlation limit of a SQUID-based noise thermometer of the pMFFT type

NASA Astrophysics Data System (ADS)

Kirste, A.; Engert, J.

2018-03-01

The primary magnetic field fluctuation thermometer (pMFFT) is a SQUID-based noise thermometer for temperatures below 1 K, which complies with metrological requirements. It combines two signal channels in order to apply the cross-correlation technique, but it requires statistically independent noise signals for proper operation. In order to check the limit of the cross-correlation readout, we have performed zero measurements in the millikelvin range in a setup that is identical to the pMFFT, except for the removed temperature sensor. We examined the influence of different parameters such as SQUID working point or flux-lock loop parameters on the minimum cross-correlation signal down to 24 mK and below 100 kHz. Depending on the configuration, typical minimum SQUID-referred cross-power spectral densities of 1.5 × 10‑15 Φ _0^2/Hz or even smaller values were observed. For the pMFFT, considering its thermal noise spectrum, these flux densities correspond to a device noise temperature of ≤2.5 µK, thereby ensuring a negligible uncertainty contribution at the lower end of the PLTS-2000 (0.9 mK).

Protecting Superconducting HTS-Antennas by Meta-Material Cloaks

DTIC Science & Technology

2014-04-30

radiation efficiency for this antenna is 22.3\\%. However, if the normal conducting part is replaced with a superconductor , e.g. YBCO with RS=500µΩ, [8] the...loss resistance can be brought down due to the much lower surface resistance of the superconductor relative to the normal conductor. Chalupka et al...range [12]. In 1987, Wu et al. [13] discovered the HTS compound YBCO that has a TC of ≈ 92K, which was the first superconductor to have a TC greater

Utilization of squid pen for the efficient production of chitosanase and antioxidants through prolonged autoclave treatment.

PubMed

Wang, San-Lang; Wu, Pei-Chen; Liang, Tzu-Wen

2009-05-26

We have developed a culture system for efficient production of chitosanase by Bacillus sp. TKU004. TKU004 was cultivated by using squid pen powder as the sole carbon/nitrogen source. The effects of autoclave treatments of the medium on the production of chitosanase were investigated. Autoclave treatment of squid pen powder for 45 min remarkably promoted enzyme productivity. When the culture medium containing an initial squid pen powder concentration of 3% was autoclaved for 45 min, the chitosanase activity was optimal and reached 0.14-0.16 U/mL. In addition, extracellular surfactant-stable chitosanase was purified from the TKU004 culture supernatant. The antioxidant activity of TKU004 culture supernatant was determined through the scavenging ability of DPPH, with 70% per mL. With this method, we have shown that marine wastes can be utilized efficiently through prolonged autoclave treatments to generate a high value-added product, and have revealed its hidden potential in the production of functional foods.

Slow swimming, fast strikes: effects of feeding behavior on scaling of anaerobic metabolism in epipelagic squid.

PubMed

Trueblood, Lloyd A; Seibel, Brad A

2014-08-01

Many pelagic fishes engage prey at high speeds supported by high metabolic rates and anaerobic metabolic capacity. Epipelagic squids are reported to have among the highest metabolic rates in the oceans as a result of demanding foraging strategies and the use of jet propulsion, which is inherently inefficient. This study examined enzymatic proxies of anaerobic metabolism in two species of pelagic squid, Dosidicus gigas and Doryteuthis pealeii (Lesueur 1821), over a size range of six orders of magnitude. We hypothesized that activity of the anaerobically poised enzymes would be high and increase with size as in ecologically similar fishes. In contrast, we demonstrate that anaerobic metabolic capacity in these organisms scales negatively with body mass. We explored several cephalopod-specific traits, such as the use of tentacles to capture prey, body morphology and reduced relative prey size of adult squids, that may create a diminished reliance on anaerobically fueled burst activity during prey capture in large animals. © 2014. Published by The Company of Biologists Ltd.

The influence of winding direction of two-layer HTS DC cable on the critical current

NASA Astrophysics Data System (ADS)

Vyatkin, V. S.; Kashiwagi, K.; Ivanov, Y. V.; Otabe, E. S.; Yamaguchi, S.

2017-09-01

The design of twist pitch and direction of winding in multilayer HTS coaxial cable is important. For HTS AC transmitting cables, the main condition of twist pitch is the balance of inductances of each layer for providing the current balance between layers. In this work, the finite element method analysis for the coaxial cables with both same and opposite directions winding is used to calculate magnetic field distribution, and critical current of the cable is estimated. It was found that the critical current of the cable with same direction winding is about 10 percent higher than that in the case of the cable with the opposite direction winding.

SQUIDs vs. Faraday coils for ultlra-low field nuclear magnetic resonance: experimental and simulation comparison

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matlashov, Andrei N; Espy, Michelle A; Kraus, Robert H

2010-01-01

Nuclear magnetic resonance (NMR) methods are widely used in medicine, chemistry and industry. One application area is magnetic resonance imaging or MRI. Recently it has become possible to perform NMR and MRI in ultra-low field (ULF) regime that requires measurement field strengths only of the order of 1 Gauss. These techniques exploit the advantages offered by superconducting quantum interference devices or SQUIDs. Our group at LANL has built SQUID based MRI systems for brain imaging and for liquid explosives detection at airports security checkpoints. The requirement for liquid helium cooling limits potential applications of ULF MRI for liquid identification andmore » security purposes. Our experimental comparative investigation shows that room temperature inductive magnetometers provide enough sensitivity in the 3-10 kHz range and can be used for fast liquid explosives detection based on ULF NMR/MRI technique. We describe an experimental and computer simulation comparison of the world's first multichannel SQUID based and Faraday coils based instruments that are capable of performing ULF MRI for liquids identification.« less

Numerical calculation of primary slot leakage inductance of a Single-sided HTS linear induction motor used for linear metro

NASA Astrophysics Data System (ADS)

Li, Dong; Wen, Yinghong; Li, Weili; Fang, Jin; Cao, Junci; Zhang, Xiaochen; Lv, Gang

2017-03-01

In the paper, the numerical method calculating asymmetric primary slot leakage inductances of Single-sided High-Temperature Superconducting (HTS) Linear Induction Motor (HTS LIM) is presented. The mathematical and geometric models of three-dimensional nonlinear transient electromagnetic field are established and the boundary conditions are also given. The established model is solved by time-stepping Finite Element Method (FEM). Then, the three-phase asymmetric primary slot leakage inductances under different operation conditions are calculated by using the obtained electromagnetic field distribution. The influences of the special effects such as longitudinal end effects, transversal edge effects, etc. on the primary slot leakage inductance are investigated. The presented numerical method is validated by experiments carried out on a 3.5 kW prototype with copper wires which has the same structures with the HTS LIM.

Numerical restoration of surface vortices in Nb films measured by a scanning SQUID microscope

NASA Astrophysics Data System (ADS)

Ito, Atsuki; Thanh Huy, Ho; Dang, Vu The; Miyoshi, Hiroki; Hayashi, Masahiko; Ishida, Takekazu

2017-07-01

In the present work, we investigated a vortex profile appeared on a pure Nb film (500 nm in thickness, 10 mm x 10 mm) by using a scanning SQUID microscope. We found that the local magnetic distribution thus observed is broadened compared to a true vortex profile in the superconducting film. We therefore applied the numerical method to improve a spatial resolution of the scanning SQUID microscope. The method is based on the inverse Biot-Savart law and the Fourier transformation to recover a real-space image. We found that the numerical analyses give a smaller vortex than the raw vortex profile observed by the scanning microscope.

Potential aerospace applications of high temperature superconductors

NASA Technical Reports Server (NTRS)

Selim, Raouf

1994-01-01

The recent discovery of High Temperature Superconductors (HTS) with superconducting transition temperature, T(sub c), above the boiling point of liquid nitrogen has opened the door for using these materials in new and practical applications. These materials have zero resistance to electric current, have the capability of carrying large currents and as such have the potential to be used in high magnetic field applications. One of the space applications that can use superconductors is electromagnetic launch of payloads to low-earth-orbit. An electromagnetic gun-type launcher can be used in small payload systems that are launched at very high velocity, while sled-type magnetically levitated launcher can be used to launch larger payloads at smaller velocities. Both types of launchers are being studied by NASA and the aerospace industry. The use of superconductors will be essential in any of these types of launchers in order to produce the large magnetic fields required to obtain large thrust forces. Low Temperature Superconductor (LTS) technology is mature enough and can be easily integrated in such systems. As for the HTS, many leading companies are currently producing HTS coils and magnets that potentially can be mass-produced for these launchers. It seems that designing and building a small-scale electromagnetic launcher is the next logical step toward seriously considering this method for launching payloads into low-earth-orbit. A second potential application is the use of HTS to build sensitive portable devices for the use in Non Destructive Evaluation (NDE). Superconducting Quantum Interference Devices (SQUID's) are the most sensitive instruments for measuring changes in magnetic flux. By using HTS in SQUID's, one will be able to design a portable unit that uses liquid nitrogen or a cryocooler pump to explore the use of gradiometers or magnetometers to detect deep cracks or corrosion in structures. A third use is the replacement of Infra-Red (IR) sensor leads on

Modeling AC ripple currents in HTS coated conductors by integral equations

NASA Astrophysics Data System (ADS)

Grilli, Francesco; Xu, Zhihan

2016-12-01

In several HTS applications, the superconducting tapes experience the simultaneous presence of DC and AC excitations. For example in high-current DC cables, where the transport current is not perfectly constant, but it exhibits some ripples at different frequencies introduced by the rectification process (AC-DC conversion). These ripples give rise to dissipation, whose magnitude and possible influence on the device's cooling requirements need to be evaluated. Here we report a study of the AC losses in a HTS coated conductor subjected to DC currents and AC ripples simultaneously. The modeling approach is based on an integral equation method for thin superconductors: the superconducting tape is modeled as a 1-D object with a non-linear resistivity, which includes the dependence of the critical current density Jc on the magnetic field. The model, implemented in a commercial finite-element program, runs very fast (the simulation of one AC cycle typically takes a few seconds on standard desktop workstation): this allows simulating a large number of cycles and estimating when the AC ripple losses stabilize to a constant value. The model is used to study the influence of the flux creep power index n on the stabilization speed and on the AC loss values, as well as the effect of using a field-dependent Jc instead of a constant one. The simulations confirm that the dissipation level should not be a practical concern in HTS DC cables. At the same time, however, they reveal a strong dependence of the results upon the power index n and the form of Jc , which spurs the question whether the power-law is the most suitable description of the superconductor's electrical behavior for this kind of analysis.

Effect of single- and two-cycle high hydrostatic pressure treatments on water properties, physicochemical and microbial qualities of minimally processed squids (todarodes pacificus).

PubMed

Zhang, Yifeng; Jiao, Shunshan; Lian, Zixuan; Deng, Yun; Zhao, Yanyun

2015-05-01

This study investigated the effect of single- and two-cycle high hydrostatic pressure (HHP) treatments on water properties, physicochemical, and microbial qualities of squids (Todarodes pacificus) during 4 °C storage for up to 10 d. Single-cycle treatments were applied at 200, 400, or 600 MPa for 20 min (S-200, S-400, and S-600), and two-cycle treatments consisted of two 10 min cycles at 200, 400, or 600 MPa, respectively (T-200, T-400, and T-600). HHP-treated samples had higher (P < 0.05) content of P2b (immobilized water) and P21 (myofibril water), but lower P22 (free water) than those of control. The single- and two-cycle HHP treatments at the same pressure level caused no significant difference in water state of squids. The two-cycle HHP treatment was more effective in controlling total volatile basic nitrogen, pH, and total plate counts (TPC) of squids during storage, in which TPC of S-600 and T-600 was 2.9 and 1.8 log CFU/g at 10 d, respectively, compared with 7.5 log CFU/g in control. HHP treatments delayed browning discoloration of the squids during storage, and the higher pressure level and two-cycle HHP were more effective. Water properties highly corresponded with color and texture indices of squids. This study demonstrated that the two-cycle HHP treatment was more effective in controlling microbial growth and quality deterioration while having similar impact on the physicochemical and water properties of squids in comparison with the single-cycle treatment, thus more desirable for extending shelf-life of fresh squids. © 2015 Institute of Food Technologists®

Aspects on HTS applications in confined power grids

NASA Astrophysics Data System (ADS)

Arndt, T.; Grundmann, J.; Kuhnert, A.; Kummeth, P.; Nick, W.; Oomen, M.; Schacherer, C.; Schmidt, W.

2014-12-01

In an increasing number of electric power grids the share of distributed energy generation is also increasing. The grids have to cope with a considerable change of power flow, which has an impact on the optimum topology of the grids and sub-grids (high-voltage, medium-voltage and low-voltage sub-grids) and the size of quasi-autonomous grid sections. Furthermore the stability of grids is influenced by its size. Thus special benefits of HTS applications in the power grid might become most visible in confined power grids.

Physicochemical characterization of actomyosin-paramyosin from giant squid mantle (Dosidicus gigas).

PubMed

Tolano-Villaverde, Ivan J; Ocaño-Higuera, Victor; Ezquerra-Brauer, Josafat; Santos-Sauceda, Irela; Santacruz-Ortega, Hisila; Cárdenas-López, José L; Rodríguez-Olibarria, Guillermo; Márquez-Ríos, Enrique

2018-03-01

The giant squid (Dosidicus gigas) has been proposed as raw material to obtain myofibrillar protein concentrates. However, it has been observed that colloidal systems formed from squid proteins have limited stability. Therefore, the isolation and characterization of the actomyosin-paramyosin isolated (API) complex were performed, because they are the main proteins to which functionality has been attributed. Densitogram analysis revealed 45% of actin, 38% of myosin and 17% of paramyosin. The amino acid profile indicates a higher proportion of acidic amino acids, which gives a higher negative charge; this was supported by the zeta potential. Total sulfhydryl (TSH) content was lower compared with proteins of other aquatic species. The higher percentage of actin in relation to myosin, the presence of paramyosin, as well as the low content of sulfhydryl groups, could comprise the main causes of the low technological functional property of proteins from D. gigas mantle. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

Combined climate- and prey-mediated range expansion of Humboldt squid (Dosidicus gigas), a large marine predator in the California Current System.

PubMed

Stewart, Julia S; Hazen, Elliott L; Bograd, Steven J; Byrnes, Jarrett E K; Foley, David G; Gilly, William F; Robison, Bruce H; Field, John C

2014-06-01

Climate-driven range shifts are ongoing in pelagic marine environments, and ecosystems must respond to combined effects of altered species distributions and environmental drivers. Hypoxic oxygen minimum zones (OMZs) in midwater environments are shoaling globally; this can affect distributions of species both geographically and vertically along with predator-prey dynamics. Humboldt (jumbo) squid (Dosidicus gigas) are highly migratory predators adapted to hypoxic conditions that may be deleterious to their competitors and predators. Consequently, OMZ shoaling may preferentially facilitate foraging opportunities for Humboldt squid. With two separate modeling approaches using unique, long-term data based on in situ observations of predator, prey, and environmental variables, our analyses suggest that Humboldt squid are indirectly affected by OMZ shoaling through effects on a primary food source, myctophid fishes. Our results suggest that this indirect linkage between hypoxia and foraging is an important driver of the ongoing range expansion of Humboldt squid in the northeastern Pacific Ocean. © 2014 John Wiley & Sons Ltd.

50 CFR 648.22 - Atlantic mackerel, squid, and butterfish specifications.

Code of Federal Regulations, 2014 CFR

2014-10-01

... squid, which, subject to annual review, may be specified for a period of up to 3 years; (2) ACL; ACT... years; (3) ACL; commercial ACT, including RSA, DAH, Tier 3 allocation (up to 7 percent of the DAH), DAP... scientific uncertainty; the stock-wide ABC must be less than or equal to the OFL. (ii) ACL. The ACL or...

50 CFR 648.22 - Atlantic mackerel, squid, and butterfish specifications.

Code of Federal Regulations, 2013 CFR

2013-10-01

... squid, which, subject to annual review, may be specified for a period of up to 3 years; (2) ACL; ACT... years; (3) ACL; commercial ACT, including RSA, DAH, Tier 3 allocation (up to 7 percent of the DAH), DAP... scientific uncertainty; the stock-wide ABC must be less than or equal to the OFL. (ii) ACL. The ACL or...

Use of in Vitro HTS-Derived Concentration–Response Data as Biological Descriptors Improves the Accuracy of QSAR Models of in Vivo Toxicity

PubMed Central

Sedykh, Alexander; Zhu, Hao; Tang, Hao; Zhang, Liying; Richard, Ann; Rusyn, Ivan; Tropsha, Alexander

2011-01-01

Background Quantitative high-throughput screening (qHTS) assays are increasingly being used to inform chemical hazard identification. Hundreds of chemicals have been tested in dozens of cell lines across extensive concentration ranges by the National Toxicology Program in collaboration with the National Institutes of Health Chemical Genomics Center. Objectives Our goal was to test a hypothesis that dose–response data points of the qHTS assays can serve as biological descriptors of assayed chemicals and, when combined with conventional chemical descriptors, improve the accuracy of quantitative structure–activity relationship (QSAR) models applied to prediction of in vivo toxicity end points. Methods We obtained cell viability qHTS concentration–response data for 1,408 substances assayed in 13 cell lines from PubChem; for a subset of these compounds, rodent acute toxicity half-maximal lethal dose (LD50) data were also available. We used the k nearest neighbor classification and random forest QSAR methods to model LD50 data using chemical descriptors either alone (conventional models) or combined with biological descriptors derived from the concentration–response qHTS data (hybrid models). Critical to our approach was the use of a novel noise-filtering algorithm to treat qHTS data. Results Both the external classification accuracy and coverage (i.e., fraction of compounds in the external set that fall within the applicability domain) of the hybrid QSAR models were superior to conventional models. Conclusions Concentration–response qHTS data may serve as informative biological descriptors of molecules that, when combined with conventional chemical descriptors, may considerably improve the accuracy and utility of computational approaches for predicting in vivo animal toxicity end points. PMID:20980217

Halide peroxidase in tissues that interact with bacteria in the host squid Euprymna scolopes.

PubMed

Small, A L; McFall-Ngai, M J

1999-03-15

An enzyme with similarities to myeloperoxidase, the antimicrobial halide peroxidase in mammalian neutrophils, occurs abundantly in the light organ tissue of Euprymna scolopes, a squid that maintains a beneficial association with the luminous bacterium Vibrio fischeri. Using three independent assays typically applied to the analysis of halide peroxidase enzymes, we directly compared the activity of the squid enzyme with that of human myeloperoxidase. One of these methods, the diethanolamine assay, confirmed that the squid peroxidase requires halide ions for its activity. The identification of a halide peroxidase in a cooperative bacterial association suggested that this type of enzyme can function not only to control pathogens, but also to modulate the interactions of host animals with their beneficial partners. To determine whether the squid peroxidase functions under both circumstances, we examined its distribution in a variety of host tissues, including those that typically interact with bacteria and those that do not. Tissues interacting with bacteria included those that have specific cooperative associations with bacteria (i.e., the light organ and accessory nidamental gland) and those that have transient nonspecific interactions with bacteria (i.e., the gills, which clear the cephalopod circulatory system of invading microorganisms). These bacteria-associated tissues were compared with the eye, digestive gland, white body, and ink-producing tissues, which do not typically interact directly with bacteria. Peroxidase enzyme assays, immunocytochemical localization, and DNA-RNA hybridizations showed that the halide-dependent peroxidase is consistently expressed in high concentration in tissues that interact bacteria. Elevated levels of the peroxidase were also found in the ink-producing tissues, which are known to have enzymatic pathways associated with antimicrobial activity. Taken together, these data suggest that the host uses a common biochemical response to

Development of a compact HTS lead unit for the SC correction coils of the SuperKEKB final focusing magnet system

NASA Astrophysics Data System (ADS)

Zong, Zhanguo; Ohuchi, Norihito; Tsuchiya, Kiyosumi; Arimoto, Yasushi

2016-09-01

Forty-three superconducting (SC) correction coils with maximum currents of about 60 A are installed in the SuperKEKB final focusing magnet system. Current leads to energize the SC correction coils should have an affordable heat load and fit the spatial constraints in the service cryostat where the current leads are installed. To address the requirements, design optimization of individual lead was performed with vapor cooled current lead made of a brass material, and a compact unit was designed to accommodate eight current leads together in order to be installed with one port in the service cryostat. The 2nd generation high temperature SC (HTS) tape was adopted and soldered at the cold end of the brass current lead to form a hybrid HTS lead structure. A prototype of the compact lead unit with HTS tape was constructed and tested with liquid helium (LHe) environment. This paper presents a cryogenic measurement system to simulate the real operation conditions in the service cryostat, and analysis of the experimental results. The measured results showed excellent agreement with the theoretical analysis and numerical simulation. In total, 11 sets of the compact HTS lead units were constructed for the 43 SC correction coils at KEK. One set from the mass production was tested in cryogenic conditions, and exhibited the same performance as the prototype. The compact HTS lead unit can feed currents to four SC correction coils simultaneously with the simple requirement of controlling and monitoring helium vapor flow, and has a heat load of about 0.762 L/h in terms of LHe consumption.

Passive radiative cooling of a HTS coil for attitude orbit control in micro-spacecraft

NASA Astrophysics Data System (ADS)

Inamori, Takaya; Ozaki, Naoya; Saisutjarit, Phongsatorn; Ohsaki, Hiroyuki

2015-02-01

This paper proposes a novel radiative cooling system for a high temperature superconducting (HTS) coil for an attitude orbit control system in nano- and micro-spacecraft missions. These days, nano-spacecraft (1-10 kg) and micro-spacecraft (10-100 kg) provide space access to a broader range of spacecraft developers and attract interest as space development applications. In planetary and high earth orbits, most previous standard-size spacecraft used thrusters for their attitude and orbit control, which are not available for nano- and micro-spacecraft missions because of the strict power consumption, space, and weight constraints. This paper considers orbit and attitude control methods that use a superconducting coil, which interacts with on-orbit space plasmas and creates a propulsion force. Because these spacecraft cannot use an active cooling system for the superconducting coil because of their mass and power consumption constraints, this paper proposes the utilization of a passive radiative cooling system, in which the superconducting coil is thermally connected to the 3 K cosmic background radiation of deep space, insulated from the heat generation using magnetic holders, and shielded from the sun. With this proposed cooling system, the HTS coil is cooled to 60 K in interplanetary orbits. Because the system does not use refrigerators for its cooling system, the spacecraft can achieve an HTS coil with low power consumption, small mass, and low cost.

Trophic relationships of albatrosses associated with squid and large-mesh drift-net fisheries in the North Pacific Ocean

USGS Publications Warehouse

Gould, Patrick J.; Ostrom, Peggy H.; Walker, William

1997-01-01

The diets of Laysan (Diomedea immutabilis) and black-footed albatrosses (D. nigripes) killed in squid and large-mesh drift nets in the transitional zone of the North Pacific Ocean were investigated by examining the contents of the digestive tracts and determining δ13C and δ15N values in breast-muscle tissue. The results show that (i) the combined prey of the two species of albatross consists of over 46 species of marine organisms including coelenterates, arthropods, mollusks, fish, and marine mammals; (ii) both species supplement their traditional diets with food made available by commercial fishing operations (e.g., net-caught squid and offal); (iii) while obtained from drift nets, diets of nonbreeding Laysan and black-footed albatrosses are dominated by neon flying squid (Ommastrephes bartrami); (iv) in the absence of drift-net-related food, Laysan albatrosses feed most heavily on fish and black-footed albatrosses feed most heavily on squid; and (v) based on δ15N values, nonbreeding adult Laysan albatrosses from the transitional zone of the North Pacific Ocean and Laysan albatross nestlings fed by adults from Midway Island in the subtropical Pacific feed at one trophic level and one-third of a trophic level lower than black-footed albatrosses, respectively.

Preparation and evaluation of squid ink polysaccharide-chitosan as a wound-healing sponge.

PubMed

Huang, Na; Lin, Jiali; Li, Sidong; Deng, Yifeng; Kong, Songzhi; Hong, Pengzhi; Yang, Ping; Liao, Mingneng; Hu, Zhang

2018-01-01

A new type of wound healing agent was developed using two marine biomaterials (squid ink polysaccharide and chitosan) as carriers and calcium chloride as an initiator for coagulation. Based on central composite design-response surface methodology, comprehensive evaluation of appearance quality for composite sponges and water absorbency were used as evaluation indices to identify the optimized preparation conditions and further evaluate the performance of the squid ink polysaccharide-chitosan sponge (SIP-CS). The optimized formulation of SIP-CS was as follows: chitosan concentration, 2.29%; squid ink polysaccharide concentration, 0.55%; and calcium chloride concentration, 2.82%, at a volume ratio of 15:5:2. SIP-CS was conducive to sticking on the wound, characterized by the spongy property, strong absorptivity, and tackiness. Rabbit ear arterial, hepatic, and femoral artery hemorrhage experiments indicated that, compared with chitosan dressings and absorbable gelatin, the hemostatic times were shorter and the bleeding volume was smaller. Furthermore, SIP-CS absorbed a large amount of hemocytes, leading to rapid hemostasis. The healing areas and wound pathological sections in scalded New Zealand rabbits indicated that SIP-CS promoted wound healing more rapidly than chitosan and better than commercially available burn cream. Thus, SIP-CS is a good wound healing agent for rapid hemostasis, promoting burn/scalded skin healing, and protecting from wound infection. Copyright © 2017 Elsevier B.V. All rights reserved.

Horizontal movements, vertical-habitat utilization and diet of the jumbo squid ( Dosidicus gigas) in the Pacific Ocean off Baja California Sur, Mexico

NASA Astrophysics Data System (ADS)

Bazzino, Gastón; Gilly, William F.; Markaida, Unai; Salinas-Zavala, César A.; Ramos-Castillejos, Jorge

2010-07-01

We deployed four pop-up archival-transmitting (PAT) tags on jumbo squid ( Dosidicus gigas) collected in the Pacific Ocean off the main entrance to Magdalena Bay on the Baja California peninsula in June 2005. This is the first successful deployment of PAT tags on jumbo squid in an area outside the Gulf of California. Summary data were obtained through the ARGOS satellite system for three of the tags; the fourth tag was physically recovered. All of the tagged squid tended to remain on the shallow continental shelf for several days after tagging and then moved offshore into deeper water. Three of the four squid appeared to migrate in a general southerly direction while the fourth remained offshore of Magdalena Bay. All of the squid spent most daylight hours at depths that were associated with the hypoxic oxygen minimum layer, and at night they spent a majority of time in the upper 50 m of the water column. Stomach content analysis and tag temperature-depth data during the first days after tagging revealed that the squid were feeding on pelagic red crabs ( Pleuroncodes planipes) and several larger, neritic fishes over the continental shelf off Magdalena Bay during a seasonal nearshore upwelling. Comparison of our results with those previously collected in the Gulf of California reveal that Dosidicus gigas can vary its behavior and diet to suit local environmental conditions. This adaptability is likely to be an important factor in the ability of D. gigas to invade and colonize new areas.

Magnetizing technique for permanent magnets by intense static fields generated by HTS bulk magnets: Numerical Analysis

NASA Astrophysics Data System (ADS)

N. Kawasaki; Oka, T.; Fukui, S.; Ogawa, J.; Sato, T.; Terasawa, T.; Itoh, Y.

A demagnetized Nd-Fe-B permanent magnet was scanned in the strong magnetic field space just above the magnetic pole containing a HTS bulk magnet which generates the magnetic field 3.4 T. The magnet sample was subsequently found to be fully magnetized in the open space of the static magnetic fields. The finite element method was carried out for the static field magnetization of a permanent magnet using a HTS bulk magnet. Previously, our research group experimentally demonstrated the possibility of full magnetization of rare earth permanent magnets with high-performance magnetic properties with use of the static field of HTS bulk magnets. In the present study, however, we succeeded for the first time in visualizing the behavior of the magnetizing field of the bulk magnet during the magnetization process and the shape of the magnetic field inside the body being magnetized. By applying this kind of numerical analysis to the magnetization for planned motor rotors which incorporate rare-earth permanent magnets, we hope to study the fully magnetized regions for the new magnetizing method using bulk magnets and to give motor designing a high degree of freedom.

Fishing ground distribution of neon flying squid ( Ommastrephes bartramii) in relation to oceanographic conditions in the Northwest Pacific Ocean

NASA Astrophysics Data System (ADS)

Yu, Wei; Chen, Xinjun; Yi, Qian

2017-12-01

Neon flying squid, Ommastrephes bartramii, is a squid species of the North Pacific Ocean, which plays an important economical role in the international fishery. Logbook data for Chinese squid-jigging fishery over 2004-2011 were used to evaluate the relationship between the fishing grounds of the squid and the convergent frontal areas, which were defined by the contour lines of specific sea surface temperature (SST) and chlorophyll- a (Chl- a) concentration. Our results indicate that the SST in the range of 15 to 19°C and the Chl- a concentration in the range of 0.1 to 0.4 mg m-3 are the favorable conditions for the aggregation of the squid. Additionally, we deduced that the SST at 17.5°C and the Chl- a concentration at 0.25 mg m-3 are the optimal environmental conditions for the aggregation of O. bartramii. In August, the annual CPUE is positively correlated with the proportion of the fishing grounds with favorable SST and Chl- a concentration, as well as the combination of the two variables, implying that the abundance of the squid annually is largely depending on the presence of the favorable environmental conditions for fishery in August. Minor spatial difference between mean latitudinal location of the 17.5°C SST and 0.25 mg m-3 Chl- a fronts can increase the CPUEs of O. bartramii. Furthermore, the monthly latitudinal gravity centers of the CPUE closely followed the mean latitudinal position of the contour lines of the 17.5°C SST and the 0.25 mg m-3 Chl- a concentration. Our findings suggest the convergent oceanographic features (fronts) play significant roles in regulating the distribution and abundance of the western stock of the winter-spring cohort of O. bartramii, which can help people to improve their ability to discover the O. bartramii fishing grounds with higher productivity.

Probe molecules (PrM) approach in adverse outcome pathway (AOP) based high throughput screening (HTS): in vivo discovery for developing in vitro target methods

EPA Science Inventory

Efficient and accurate adverse outcome pathway (AOP) based high-throughput screening (HTS) methods use a systems biology based approach to computationally model in vitro cellular and molecular data for rapid chemical prioritization; however, not all HTS assays are grounded by rel...

Microplate-Based Method for High-Throughput Screening (HTS) of Chromatographic Conditions Studies for Recombinant Protein Purification.

PubMed

Carvalho, Rimenys J; Cruz, Thayana A

2018-01-01

High-throughput screening (HTS) systems have emerged as important tools to provide fast and low cost evaluation of several conditions at once since it requires small quantities of material and sample volumes. These characteristics are extremely valuable for experiments with large number of variables enabling the application of design of experiments (DoE) strategies or simple experimental planning approaches. Once, the capacity of HTS systems to mimic chromatographic purification steps was established, several studies were performed successfully including scale down purification. Here, we propose a method for studying different purification conditions that can be used for any recombinant protein, including complex and glycosylated proteins, using low binding filter microplates.

50 CFR 648.22 - Atlantic mackerel, squid, and butterfish specifications.

Code of Federal Regulations, 2012 CFR

2012-10-01

... squid, which, subject to annual review, may be specified for a period of up to 3 years; (2) ACL; ACT... years; (3) ACL; commercial ACT, including RSA, DAH, Tier 3 allocation (up to 7 percent of the DAH), DAP... ABC must be less than or equal to the OFL. (ii) ACL. The ACL or Domestic ABC is calculated using the...

The HTS barcode checker pipeline, a tool for automated detection of illegally traded species from high-throughput sequencing data.

PubMed

Lammers, Youri; Peelen, Tamara; Vos, Rutger A; Gravendeel, Barbara

2014-02-06

Mixtures of internationally traded organic substances can contain parts of species protected by the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). These mixtures often raise the suspicion of border control and customs offices, which can lead to confiscation, for example in the case of Traditional Chinese medicines (TCMs). High-throughput sequencing of DNA barcoding markers obtained from such samples provides insight into species constituents of mixtures, but manual cross-referencing of results against the CITES appendices is labor intensive. Matching DNA barcodes against NCBI GenBank using BLAST may yield misleading results both as false positives, due to incorrectly annotated sequences, and false negatives, due to spurious taxonomic re-assignment. Incongruence between the taxonomies of CITES and NCBI GenBank can result in erroneous estimates of illegal trade. The HTS barcode checker pipeline is an application for automated processing of sets of 'next generation' barcode sequences to determine whether these contain DNA barcodes obtained from species listed on the CITES appendices. This analytical pipeline builds upon and extends existing open-source applications for BLAST matching against the NCBI GenBank reference database and for taxonomic name reconciliation. In a single operation, reads are converted into taxonomic identifications matched with names on the CITES appendices. By inclusion of a blacklist and additional names databases, the HTS barcode checker pipeline prevents false positives and resolves taxonomic heterogeneity. The HTS barcode checker pipeline can detect and correctly identify DNA barcodes of CITES-protected species from reads obtained from TCM samples in just a few minutes. The pipeline facilitates and improves molecular monitoring of trade in endangered species, and can aid in safeguarding these species from extinction in the wild. The HTS barcode checker pipeline is available at https://github.com/naturalis/HTS-barcode-checker.

The HTS barcode checker pipeline, a tool for automated detection of illegally traded species from high-throughput sequencing data

PubMed Central

2014-01-01

Background Mixtures of internationally traded organic substances can contain parts of species protected by the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). These mixtures often raise the suspicion of border control and customs offices, which can lead to confiscation, for example in the case of Traditional Chinese medicines (TCMs). High-throughput sequencing of DNA barcoding markers obtained from such samples provides insight into species constituents of mixtures, but manual cross-referencing of results against the CITES appendices is labor intensive. Matching DNA barcodes against NCBI GenBank using BLAST may yield misleading results both as false positives, due to incorrectly annotated sequences, and false negatives, due to spurious taxonomic re-assignment. Incongruence between the taxonomies of CITES and NCBI GenBank can result in erroneous estimates of illegal trade. Results The HTS barcode checker pipeline is an application for automated processing of sets of 'next generation’ barcode sequences to determine whether these contain DNA barcodes obtained from species listed on the CITES appendices. This analytical pipeline builds upon and extends existing open-source applications for BLAST matching against the NCBI GenBank reference database and for taxonomic name reconciliation. In a single operation, reads are converted into taxonomic identifications matched with names on the CITES appendices. By inclusion of a blacklist and additional names databases, the HTS barcode checker pipeline prevents false positives and resolves taxonomic heterogeneity. Conclusions The HTS barcode checker pipeline can detect and correctly identify DNA barcodes of CITES-protected species from reads obtained from TCM samples in just a few minutes. The pipeline facilitates and improves molecular monitoring of trade in endangered species, and can aid in safeguarding these species from extinction in the wild. The HTS barcode checker pipeline is

Phylogeographical patterns among Mediterranean sepiolid squids and their Vibrio symbionts: environment drives specificity among sympatric species.

PubMed

Zamborsky, D J; Nishiguchi, M K

2011-01-01

Bobtail squid from the genera Sepiola and Rondeletiola (Cephalopoda: Sepiolidae) form mutualistic associations with luminous Gram-negative bacteria (Gammaproteobacteria: Vibrionaceae) from the genera Vibrio and Photobacterium. Symbiotic bacteria proliferate inside a bilobed light organ until they are actively expelled by the host into the surrounding environment on a diel basis. This event results in a dynamic symbiont population with the potential to establish the symbiosis with newly hatched sterile (axenic) juvenile sepiolids. In this study, we examined the genetic diversity found in populations of sympatric sepiolid squid species and their symbionts by the use of nested clade analysis with multiple gene analyses. Variation found in the distribution of different species of symbiotic bacteria suggests a strong influence of abiotic factors in the local environment, affecting bacterial distribution among sympatric populations of hosts. These abiotic factors include temperature differences incurred by a shallow thermocline, as well as a lack of strong coastal water movement accompanied by seasonal temperature changes in overlapping niches. Host populations are stable and do not appear to have a significant role in the formation of symbiont populations relative to their distribution across the Mediterranean Sea. Additionally, all squid species examined (Sepiola affinis, S. robusta, S. ligulata, S. intermedia, and Rondeletiola minor) are genetically distinct from one another regardless of location and demonstrate very little intraspecific variation within species. These findings suggest that physical boundaries and distance in relation to population size, and not host specificity, are important factors in limiting or defining gene flow within sympatric marine squids and their associated bacterial symbionts in the Mediterranean Sea.

A perspective on 10-years HTS experience at the Walter and Eliza Hall Institute of Medical Research - eighteen million assays and counting.

PubMed

Lackovic, Kurt; Lessene, Guillaume; Falk, Hendrik; Leuchowius, Karl-Johan; Baell, Jonathan; Street, Ian

2014-03-01

The Walter and Eliza Hall Institute of Medical Research (WEHI) is Australia's longest serving medical research institute. WEHI's High Throughput Screening (HTS) Facility was established in 2003 with $5 million of infrastructure funds invested by WEHI, and the Victorian State Government's Strategic Technology Initiative through Bio21 Australia Ltd. The Facility was Australia's first truly academic HTS facility and was one of only a handful operating in publicly funded institutions worldwide at that time. The objectives were to provide access to enabling HTS technologies, such as assay design, liquid handling automation, compound libraries and expertise to promote translation of basic research in a national setting that has a relatively young biotech sector and does not have a big Pharma research presence. Ten years on and the WEHI HTS Facility has participated in over 92 collaborative projects, generated over 18 million data points, and most importantly, projects that began in the Facility have been commercialized successfully (due to strong ties with Business Development and emphasis on intellectual property management) and now have molecules progressing in clinical trials.

Hydrolysates from scallop and squid processing byproducts as specialty aquafeed ingredients

USDA-ARS?s Scientific Manuscript database

Around 9,000 MT of squid (Loligo pealei) is landed annually in Rhode Island, USA, most of which is processed resulting in 40-50% unutilized byproducts (about 3,500 MT). On the other hand, the sea scallop (Placopecten magellanicus) resource off New England is currently at historic high levels of 22,7...

Ventilation rates and activity levels of juvenile jumbo squid under metabolic suppression in the oxygen minimum zone.

PubMed

Trübenbach, Katja; Pegado, Maria R; Seibel, Brad A; Rosa, Rui

2013-02-01

The Humboldt (jumbo) squid, Dosidicus gigas, is a part-time resident of the permanent oxygen minimum zone (OMZ) in the Eastern Tropical Pacific and, thereby, it encounters oxygen levels below its critical oxygen partial pressure. To better understand the ventilatory mechanisms that accompany the process of metabolic suppression in these top oceanic predators, we exposed juvenile D. gigas to the oxygen levels found in the OMZ (1% O(2), 1 kPa, 10 °C) and measured metabolic rate, activity cycling patterns, swimming mode, escape jet (burst) frequency, mantle contraction frequency and strength, stroke volume and oxygen extraction efficiency. In normoxia, metabolic rate varied between 14 and 29 μmol O(2) g(-1) wet mass h(-1), depending on the level of activity. The mantle contraction frequency and strength were linearly correlated and increased significantly with activity level. Additionally, an increase in stroke volume and ventilatory volume per minute was observed, followed by a mantle hyperinflation process during high activity periods. Squid metabolic rate dropped more than 75% during exposure to hypoxia. Maximum metabolic rate was not achieved under such conditions and the metabolic scope was significantly decreased. Hypoxia changed the relationship between mantle contraction strength and frequency from linear to polynomial with increasing activity, indicating that, under hypoxic conditions, the jumbo squid primarily increases the strength of mantle contraction and does not regulate its frequency. Under hypoxia, jumbo squid also showed a larger inflation period (reduced contraction frequency) and decreased relaxed mantle diameter (shortened diffusion pathway), which optimize oxygen extraction efficiency (up to 82%/34%, without/with consideration of 60% potential skin respiration). Additionally, they breathe 'deeply', with more powerful contractions and enhanced stroke volume. This deep-breathing behavior allows them to display a stable ventilatory volume per

Chromogenic behaviors of the Humboldt squid (Dosidicus gigas) studied in situ with an animal-borne video package.

PubMed

Rosen, Hannah; Gilly, William; Bell, Lauren; Abernathy, Kyler; Marshall, Greg

2015-01-15

Dosidicus gigas (Humboldt or jumbo flying squid) is an economically and ecologically influential species, yet little is known about its natural behaviors because of difficulties in studying this active predator in its oceanic environment. By using an animal-borne video package, National Geographic's Crittercam, we were able to observe natural behaviors in free-swimming D. gigas in the Gulf of California with a focus on color-generating (chromogenic) behaviors. We documented two dynamic displays without artificial lighting at depths of up to 70 m. One dynamic pattern, termed 'flashing' is characterized by a global oscillation (2-4 Hz) of body color between white and red. Flashing was almost always observed when other squid were visible in the video frame, and this behavior presumably represents intraspecific signaling. Amplitude and frequency of flashing can be modulated, and the phase relationship with another squid can also be rapidly altered. Another dynamic display termed 'flickering' was observed whenever flashing was not occurring. This behavior is characterized by irregular wave-like activity in neighboring patches of chromatophores, and the resulting patterns mimic reflections of down-welled light in the water column, suggesting that this behavior may provide a dynamic type of camouflage. Rapid and global pauses in flickering, often before a flashing episode, indicate that flickering is under inhibitory neural control. Although flashing and flickering have not been described in other squid, functional similarities are evident with other species. © 2015. Published by The Company of Biologists Ltd.

Conductivity tomography based on pulsed eddy current with SQUID magnetometer

NASA Astrophysics Data System (ADS)

Panaitov, G. I.; Krause, H.-J.; Zhang, Y.

2002-05-01

Pulsed eddy current (EC) techniques have the advantage of potentially covering a broader depth range than standard single frequency EC testing. We developed a novel pulsed EC technique using a liquid-nitrogen cooled SQUID magnetometer. For two reasons, SQUID magnetometers are particularly well suited as sensors: first they constitute an extremely sensitive magnetic field sensor, second they measure the field directly which decays more slowly than its time derivative picked up by induction coils. A square waveform transmitter signal was used, with alternating slopes in order to eliminate drift effect, and stacking synchronous to the power line frequency in order to improve signal-to-noise. The early time (high frequency) data of the recorded transient correspond to the upper layers of the conducting medium, while late time data or low frequencies deliver information on deep layers. Measurements of cracks at different depths in a stacked aluminum sample are presented. From the measured data, the apparent conductivity of the sample was calculated for each position and depth by applying a technique known from geophysical data interpretation. Thus, the position and depth of the crack was determined from the tomographic conductivity image of the sample.

Squid-inspired vehicle design using coupled fluid-solid analytical modeling

NASA Astrophysics Data System (ADS)

Giorgio-Serchi, Francesco; Weymouth, Gabriel

2017-11-01

The need for enhanced automation in the marine and maritime fields is fostering research into robust and highly maneuverable autonomous underwater vehicles. To address these needs we develop design principles for a new generation of soft-bodied aquatic vehicles similar to octopi and squids. In particular, we consider the capability of pulsed-jetting bodies to boost thrust by actively modifying their external body-shape and in this way benefit of the contribution from added-mass variation. We present an analytical formulation of the coupled fluid-structure interaction between the elastic body and the ambient fluid. The model incorporates a number of new salient contributions to the soft-body dynamics. We highlight the role of added-mass variation effects of the external fluid in enhancing thrust and assess how the shape-changing actuation is impeded by a confinement-related unsteady inertial term and by an external shape-dependent fluid stiffness contribution. We show how the analysis of these combined terms has guided us to the design of a new prototype of a squid-inspired vehicle tuning of the natural frequency of the coupled fluid-solid system with the purpose of optimizing its actuation routine.

Impact of SQUIDs on functional imaging in neuroscience

NASA Astrophysics Data System (ADS)

Della Penna, Stefania; Pizzella, Vittorio; Romani, Gian Luca

2014-04-01

This paper provides an overview on the basic principles and applications of magnetoencephalography (MEG), a technique that requires the use of many SQUIDs and thus represents one of the most important applications of superconducting electronics. Since the development of the first SQUID magnetometers, it was clear that these devices could be used to measure the ultra-low magnetic signals associated with the bioelectric activity of the neurons of the human brain. Forty years on from the first measurement of magnetic alpha rhythm by David Cohen, MEG has become a fundamental tool for the investigation of brain functions. The simple localization of cerebral sources activated by sensory stimulation performed in the early years has been successively expanded to the identification of the sequence of neuronal pool activations, thus decrypting information of the hierarchy underlying cerebral processing. This goal has been achieved thanks to the development of complex instrumentation, namely whole head MEG systems, allowing simultaneous measurement of magnetic fields all over the scalp with an exquisite time resolution. The latest trends in MEG, such as the study of brain networks, i.e. how the brain organizes itself in a coherent and stable way, are discussed. These sound applications together with the latest technological developments aimed at implementing systems able to record MEG signals and magnetic resonance imaging (MRI) of the head with the same set-up pave the way to high performance systems for brain functional investigation in the healthy and the sick population.

Experimental determination of refractive index of condensed reflectin in squid iridocytes.

PubMed

Ghoshal, Amitabh; DeMartini, Daniel G; Eck, Elizabeth; Morse, Daniel E

2014-06-06

Loliginid squid dynamically tune the structural iridescence of cells in their skin for active camouflage and communication. Bragg reflectors in these cells consist of membrane-bound lamellae periodically alternating with low refractive index extracellular spaces; neuronal signalling induces condensation of the reflectin proteins that fill the lamellae, consequently triggering the expulsion of water. This causes an increase in refractive index within the lamellae, activating reflectance, with the change in lamellar thickness and spacing progressively shifting the wavelength of reflected light. We used micro-spectrophotometry to measure the functionally relevant refractive index of the high-index lamellae of the Bragg reflectors containing the condensed reflectins in chemically fixed dermal iridocytes of the squid, Doryteuthis opalescens. Our high-magnification imaging spectrometer allowed us to obtain normalized spectra of optically distinct sections of the individual, subcellular, multi-layer Bragg stacks. Replacement of the extracellular fluid with liquids of increasing refractive index allowed us to measure the reflectivity of the Bragg stacks as it decreased progressively to 0 when the refractive index of the extracellular medium exactly matched that of the reflectin-filled lamellae, thus allowing us to directly measure the refractive index of the reflectin-filled lamellae as ncondensed lamellae ≈ 1.44. The measured value of the physiologically relevant ncondensed lamellae from these bright iridocytes falls within the range of values that we recently determined by an independent optical method and is significantly lower than values previously reported for dehydrated and air-dried reflectin films. We propose that this directly measured value for the refractive index of the squid's Bragg lamellae containing the condensed reflectins is most appropriate for calculations of reflectivity in similar reflectin-based high-index layers in other molluscs.

Experimental determination of refractive index of condensed reflectin in squid iridocytes

PubMed Central

Ghoshal, Amitabh; DeMartini, Daniel G.; Eck, Elizabeth; Morse, Daniel E.

2014-01-01

Loliginid squid dynamically tune the structural iridescence of cells in their skin for active camouflage and communication. Bragg reflectors in these cells consist of membrane-bound lamellae periodically alternating with low refractive index extracellular spaces; neuronal signalling induces condensation of the reflectin proteins that fill the lamellae, consequently triggering the expulsion of water. This causes an increase in refractive index within the lamellae, activating reflectance, with the change in lamellar thickness and spacing progressively shifting the wavelength of reflected light. We used micro-spectrophotometry to measure the functionally relevant refractive index of the high-index lamellae of the Bragg reflectors containing the condensed reflectins in chemically fixed dermal iridocytes of the squid, Doryteuthis opalescens. Our high-magnification imaging spectrometer allowed us to obtain normalized spectra of optically distinct sections of the individual, subcellular, multi-layer Bragg stacks. Replacement of the extracellular fluid with liquids of increasing refractive index allowed us to measure the reflectivity of the Bragg stacks as it decreased progressively to 0 when the refractive index of the extracellular medium exactly matched that of the reflectin-filled lamellae, thus allowing us to directly measure the refractive index of the reflectin-filled lamellae as ncondensed lamellae ≈ 1.44. The measured value of the physiologically relevant ncondensed lamellae from these bright iridocytes falls within the range of values that we recently determined by an independent optical method and is significantly lower than values previously reported for dehydrated and air-dried reflectin films. We propose that this directly measured value for the refractive index of the squid's Bragg lamellae containing the condensed reflectins is most appropriate for calculations of reflectivity in similar reflectin-based high-index layers in other molluscs. PMID:24694894

Range expansion of the jumbo squid in the NE Pacific: δ15N decrypts multiple origins, migration and habitat use.

PubMed

Ruiz-Cooley, Rocio I; Ballance, Lisa T; McCarthy, Matthew D

2013-01-01

Coincident with climate shifts and anthropogenic perturbations, the highly voracious jumbo squid Dosidicus gigas reached unprecedented northern latitudes along the NE Pacific margin post 1997-98. The physical or biological drivers of this expansion, as well as its ecological consequences remain unknown. Here, novel analysis from both bulk tissues and individual amino acids (Phenylalanine; Phe and Glutamic acid; Glu) in both gladii and muscle of D. gigas captured in the Northern California Current System (NCCS) documents for the first time multiple geographic origins and migration. Phe δ(15)N values, a proxy for habitat baseline δ(15)N values, confirm at least three different geographic origins that were initially detected by highly variable bulk δ(15)N values in gladii for squid at small sizes (<30 cm gladii length). In contrast, bulk δ(15)N values from gladii of large squid (>60 cm) converged, indicating feeding in a common ecosystem. The strong latitudinal gradient in Phe δ(15)N values from composite muscle samples further confirmed residency at a point in time for large squid in the NCCS. These results contrast with previous ideas, and indicate that small squid are highly migratory, move into the NCCS from two or more distinct geographic origins, and use this ecosystem mainly for feeding. These results represent the first direct information on the origins, immigration and habitat use of this key "invasive" predator in the NCCS, with wide implications for understanding both the mechanisms of periodic D. gigas population range expansions, and effects on ecosystem trophic structure.

Range Expansion of the Jumbo Squid in the NE Pacific: δ15N Decrypts Multiple Origins, Migration and Habitat Use

PubMed Central

Ruiz-Cooley, Rocio I.; Ballance, Lisa T.; McCarthy, Matthew D.

2013-01-01

Coincident with climate shifts and anthropogenic perturbations, the highly voracious jumbo squid Dosidicus gigas reached unprecedented northern latitudes along the NE Pacific margin post 1997–98. The physical or biological drivers of this expansion, as well as its ecological consequences remain unknown. Here, novel analysis from both bulk tissues and individual amino acids (Phenylalanine; Phe and Glutamic acid; Glu) in both gladii and muscle of D. gigas captured in the Northern California Current System (NCCS) documents for the first time multiple geographic origins and migration. Phe δ15N values, a proxy for habitat baseline δ15N values, confirm at least three different geographic origins that were initially detected by highly variable bulk δ15N values in gladii for squid at small sizes (<30 cm gladii length). In contrast, bulk δ15N values from gladii of large squid (>60 cm) converged, indicating feeding in a common ecosystem. The strong latitudinal gradient in Phe δ15N values from composite muscle samples further confirmed residency at a point in time for large squid in the NCCS. These results contrast with previous ideas, and indicate that small squid are highly migratory, move into the NCCS from two or more distinct geographic origins, and use this ecosystem mainly for feeding. These results represent the first direct information on the origins, immigration and habitat use of this key “invasive” predator in the NCCS, with wide implications for understanding both the mechanisms of periodic D. gigas population range expansions, and effects on ecosystem trophic structure. PMID:23527242

SQUID-based current sensing noise thermometry for quantum resistors at dilution refrigerator temperatures

NASA Astrophysics Data System (ADS)

Kleinbaum, Ethan; Shingla, Vidhi; Csáthy, G. A.

2017-03-01

We present a dc Superconducting QUantum Interference Device (SQUID)-based current amplifier with an estimated input referred noise of only 2.3 fA/√{Hz}. Because of such a low amplifier noise, the circuit is useful for Johnson noise thermometry of quantum resistors in the kΩ range down to mK temperatures. In particular, we demonstrate that our circuit does not contribute appreciable noise to the Johnson noise of a 3.25 kΩ resistor down to 16 mK. Our circuit is a useful alternative to the commonly used High Electron Mobility Transistor-based amplifiers, but in contrast to the latter, it offers a much reduced 1/f noise. In comparison to SQUIDs interfaced with cryogenic current comparators, our circuit has similar low noise levels, but it is easier to build and to shield from magnetic pickup.

Variability of Suitable Habitat of Western Winter-Spring Cohort for Neon Flying Squid in the Northwest Pacific under Anomalous Environments.

PubMed

Yu, Wei; Chen, Xinjun; Yi, Qian; Chen, Yong; Zhang, Yang

2015-01-01

We developed a habitat suitability index (HSI) model to evaluate the variability of suitable habitat for neon flying squid (Ommastrephes bartramii) under anomalous environments in the Northwest Pacific Ocean. Commercial fisheries data from the Chinese squid-jigging vessels on the traditional fishing ground bounded by 35°-45°N and 150°-175°E from July to November during 1998-2009 were used for analyses, as well as the environmental variables including sea surface temperature (SST), chlorophyll-a (Chl-a) concentration, sea surface height anomaly (SSHA) and sea surface salinity (SSS). Two empirical HSI models (arithmetic mean model, AMM; geometric mean model, GMM) were established according to the frequency distribution of fishing efforts. The AMM model was found to perform better than the GMM model. The AMM-based HSI model was further validated by the fishery and environmental data in 2010. The predicted HSI values in 1998 (high catch), 2008 (average catch) and 2009 (low catch) indicated that the squid habitat quality was strongly associated with the ENSO-induced variability in the oceanic conditions on the fishing ground. The La Niña events in 1998 tended to yield warm SST and favorable range of Chl-a concentration and SSHA, resulting in high-quality habitats for O. bartramii. While the fishing ground in the El Niño year of 2009 experienced anomalous cool waters and unfavorable range of Chl-a concentration and SSHA, leading to relatively low-quality squid habitats. Our findings suggest that the La Niña event in 1998 tended to result in more favorable habitats for O. bartramii in the Northwest Pacific with the gravity centers of fishing efforts falling within the defined suitable habitat and yielding high squid catch; whereas the El Niño event in 2009 yielded less favorable habitat areas with the fishing effort distribution mismatching the suitable habitat and a dramatic decline of the catch of O. bartramii. This study might provide some potentially valuable

HTS Transmission Cable System for installation in the Long Island Power Grid

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schmidt, Frank; Durand, Fabien; Maguire, James

2015-10-05

Department of Energy (DOE) Award DE-FC26-07NT43240 was issued on October 1, 2007. Referred to as LIPA2, the principal objectives of the project were to develop key components required to deploy and demonstrate second-generation (2G) high temperature superconductor (HTS) cables in a 600 meter (2000 feet) underground segment of a 138kV three-phase transmission circuit of the Long Island Power Authority (LIPA) power grid. A previous effort under DOE Award DE-FC36-03GO13032 (referred to as LIPA1) resulted in installation (and subsequent successful operation) of first-generation (1G) HTS cables at the LIPA site. As with LIPA1, American Superconductor (AMSC) led the effort for LIPA2more » and was responsible for overall management of the project and producing sufficient 2G wire to fabricate the required cable. Nexans' tasks included design/manufacture/installation of the cable, joint (splice), cable terminations and field repairable cryostat; while work by Air Liquide involved engineering and installation support for the refrigeration system modifications.« less

Correlations Between Magnetic Flux and Levitation Force of HTS Bulk Above a Permanent Magnet Guideway

NASA Astrophysics Data System (ADS)

Huang, Huan; Zheng, Jun; Zheng, Botian; Qian, Nan; Li, Haitao; Li, Jipeng; Deng, Zigang

2017-10-01

In order to clarify the correlations between magnetic flux and levitation force of the high-temperature superconducting (HTS) bulk, we measured the magnetic flux density on bottom and top surfaces of a bulk superconductor while vertically moving above a permanent magnet guideway (PMG). The levitation force of the bulk superconductor was measured simultaneously. In this study, the HTS bulk was moved down and up for three times between field-cooling position and working position above the PMG, followed by a relaxation measurement of 300 s at the minimum height position. During the whole processes, the magnetic flux density and levitation force of the bulk superconductor were recorded and collected by a multipoint magnetic field measurement platform and a self-developed maglev measurement system, respectively. The magnetic flux density on the bottom surface reflected the induced field in the superconductor bulk, while on the top, it reveals the penetrated magnetic flux. The results show that the magnetic flux density and levitation force of the bulk superconductor are in direct correlation from the viewpoint of inner supercurrent. In general, this work is instructive for understanding the connection of the magnetic flux density, the inner current density and the levitation behavior of HTS bulk employed in a maglev system. Meanwhile, this magnetic flux density measurement method has enriched present experimental evaluation methods of maglev system.

Integrated design of cryogenic refrigerator and liquid-nitrogen circulation loop for HTS cable

NASA Astrophysics Data System (ADS)

Chang, Ho-Myung; Ryu, Ki Nam; Yang, Hyung Suk

2016-12-01

A new concept of cryogenic cooling system is proposed and investigated for application to long-length HTS cables. One of major obstacles to the cable length of 1 km or longer is the difficulty in circulating liquid nitrogen (LN) along the cables, since the temperature rise and pressure drop of LN flow could be excessively large. This study attempts a breakthrough by integrating the refrigerator with the LN circulation loop in order to eliminate the cryogenic LN pumps, and generate a large LN flow with the power of compressors at ambient temperature. A variety of thermodynamic structures are investigated on standard and modified Claude cycles, where nitrogen is used as refrigerant and the LN circulation loop is included as part of the closed cycle. Four proposed cycles are fully analyzed and optimized with a process simulator (Aspen HYSYS) to evaluate the FOM (figure of merit) and examine the feasibility. The modified dual-pressure cycle cooled with expander stream is recommended for long HTS cables.

Potential role for microRNA in regulating hypoxia-induced metabolic suppression in jumbo squids.

PubMed

Hadj-Moussa, Hanane; Logan, Samantha M; Seibel, Brad A; Storey, Kenneth B

2018-05-02

At night, Humboldt squid (Dosidicus gigas) rise to the ocean's surface to feed, but come morning, they descend into the ocean's oxygen minimum zone where they can avoid predators but must deal with severe hypoxia, high pressure, and very cold water. To survive this extreme environment, squid use various adaptations to enter a hypometabolic state characterized by metabolic rate suppression by 35-52%, relative to normoxic conditions. The molecular mechanisms facilitating this metabolic flexibility have yet to be elucidated in hypometabolic squid. Herein, we report the first investigation of the role of microRNAs, a rapid and reversible post-transcriptional master regulator of virtually all biological functions, in cephalopods. We examined expression levels of 39 highly-conserved invertebrate microRNAs in D. gigas brain, mantle muscle, and branchial heart, comparing hypoxic and normoxic conditions. Hypoxia-inducible microRNAs are potentially involved in facilitating neuroprotection, anti-apoptosis, and regenerative mechanisms in brain; inhibiting apoptosis and cell proliferation while conserving energy in heart; and limiting damage by reactive oxygen species and apoptosis in muscle. Rather than orchestrate global metabolic rate depression, the majority of hypoxia-inducible microRNAs identified are involved in promoting cytoprotective mechanisms, suggesting a regulatory role for microRNA in hypoxic marine invertebrates that sets the stage for mechanistic analyses. Copyright © 2018 Elsevier B.V. All rights reserved.

Microfossil evidence for a mid-Jurassic squid egg-laying area in association with the Christian Malford Lagerstätte

NASA Astrophysics Data System (ADS)

Hart, Malcolm; de Jonghe, Alex; Duff, Keith; Page, Kevin; Price, Gregory; Smart, Christopher; Wilby, Philip

2010-05-01

In the 1840s, during the construction of the Great Western Railway west of Swindon, a number of beautifully preserved coleoids (belemnites and squid-like cephalopods) were found. These famous specimens of Belemnoteuthis and Mastigophora, as well as a number of fish, were eventually described as a fossil lagerstätte under the name of the "Christian Malford Squid Bed". Many of these specimens, which come from the Phaeinum Zone (Callovian) of the Oxford Clay Formation, contain soft tissue, muscle fibres and the content of their ink sacs. In October 2007 the British Geological Survey funded an excavation of the site some ~100 m from the original borrow pits alongside the railway. This pit yielded some new coleoid specimens as well as many ammonites, bivalves and gastropods, all of which are exquisitely preserved. Some of the bedding surfaces recovered are plastered with monospecific assemblages of foraminifera (In the 1840s, during the construction of the Great Western Railway west of Swindon, a number of beautifully preserved coleoids (belemnites and squid-like cephalopods) were found. These famous specimens of Belemnoteuthis and Mastigophora, as well as a number of fish, were eventually described as a fossil lagerstätte under the name of the "Christian Malford Squid Bed". Many of these specimens, which come from the Phaeinum Zone (Callovian) of the Oxford Clay Formation, contain soft tissue, muscle fibres and the content of their ink sacs. In October 2007 the British Geological Survey funded an excavation of the site some ~100 m from the original borrow pits alongside the railway. This pit yielded some new coleoid specimens as well as many ammonites, bivalves and gastropods, all of which are exquisitely preserved. Some of the bedding surfaces recovered are plastered with monospecific assemblages of foraminifera (Epistomina spp.). Our work on borehole core No. 10 (from the same location) has recovered exceptionally large numbers of statoliths, otoliths (fish �

High-Throughput Screening by Nuclear Magnetic Resonance (HTS by NMR) for the Identification of PPIs Antagonists.

PubMed

Wu, Bainan; Barile, Elisa; De, Surya K; Wei, Jun; Purves, Angela; Pellecchia, Maurizio

2015-01-01

In recent years the ever so complex field of drug discovery has embraced novel design strategies based on biophysical fragment screening (fragment-based drug design; FBDD) using nuclear magnetic resonance spectroscopy (NMR) and/or structure-guided approaches, most often using X-ray crystallography and computer modeling. Experience from recent years unveiled that these methods are more effective and less prone to artifacts compared to biochemical high-throughput screening (HTS) of large collection of compounds in designing protein inhibitors. Hence these strategies are increasingly becoming the most utilized in the modern pharmaceutical industry. Nonetheless, there is still an impending need to develop innovative and effective strategies to tackle other more challenging targets such as those involving protein-protein interactions (PPIs). While HTS strategies notoriously fail to identify viable hits against such targets, few successful examples of PPIs antagonists derived by FBDD strategies exist. Recently, we reported on a new strategy that combines some of the basic principles of fragment-based screening with combinatorial chemistry and NMR-based screening. The approach, termed HTS by NMR, combines the advantages of combinatorial chemistry and NMR-based screening to rapidly and unambiguously identify bona fide inhibitors of PPIs. This review will reiterate the critical aspects of the approach with examples of possible applications.

High-throughput screening by Nuclear Magnetic Resonance (HTS by NMR) for the identification of PPIs antagonists

PubMed Central

Wu, Bainan; Barile, Elisa; De, Surya K.; Wei, Jun; Purves, Angela; Pellecchia, Maurizio

2015-01-01

In recent years the ever so complex field of drug discovery has embraced novel design strategies based on biophysical fragment screening (fragment-based drug design; FBDD) using nuclear magnetic resonance spectroscopy (NMR) and/or structure-guided approaches, most often using X-ray crystallography and computer modeling. Experience from recent years unveiled that these methods are more effective and less prone to artifacts compared to biochemical high-throughput screening (HTS) of large collection of compounds in designing protein inhibitors. Hence these strategies are increasingly becoming the most utilized in the modern pharmaceutical industry. Nonetheless, there is still an impending need to develop innovative and effective strategies to tackle other more challenging targets such as those involving protein-protein interactions (PPIs). While HTS strategies notoriously fail to identify viable hits against such targets, few successful examples of PPIs antagonists derived by FBDD strategies exist. Recently, we reported on a new strategy that combines some of the basic principles of fragment-based screening with combinatorial chemistry and NMR-based screening. The approach, termed HTS by NMR, combines the advantages of combinatorial chemistry and NMR-based screening to rapidly and unambiguously identify bona fide inhibitors of PPIs. This review will reiterate the critical aspects of the approach with examples of possible applications. PMID:25986689

A conserved chemical dialog of mutualism: lessons from squid and vibrio

PubMed Central

Schwartzman, Julia A.; Ruby, Edward G.

2015-01-01

Microorganisms shape, and are shaped by, their environment. In host-microbe associations, this environment is defined by tissue chemistry, which reflects local and organism-wide physiology, as well as inflammatory status. We review how, in the squid-vibrio mutualism, both partners shape tissue chemistry, revealing common themes governing tissue homeostasis in animal-microbe associations. PMID:26384815

Body Size Regression Formulae, Proximate Composition and Energy Density of Eastern Bering Sea Mesopelagic Fish and Squid

PubMed Central

2015-01-01

The ecological significance of fish and squid of the mesopelagic zone (200 m–1000 m) is evident by their pervasiveness in the diets of a broad spectrum of upper pelagic predators including other fishes and squids, seabirds and marine mammals. As diel vertical migrators, mesopelagic micronekton are recognized as an important trophic link between the deep scattering layer and upper surface waters, yet fundamental aspects of the life history and energetic contribution to the food web for most are undescribed. Here, we present newly derived regression equations for 32 species of mesopelagic fish and squid based on the relationship between body size and the size of hard parts typically used to identify prey species in predator diet studies. We describe the proximate composition and energy density of 31 species collected in the eastern Bering Sea during May 1999 and 2000. Energy values are categorized by body size as a proxy for relative age and can be cross-referenced with the derived regression equations. Data are tabularized to facilitate direct application to predator diet studies and food web models. PMID:26287534

Body Size Regression Formulae, Proximate Composition and Energy Density of Eastern Bering Sea Mesopelagic Fish and Squid.

PubMed

Sinclair, Elizabeth H; Walker, William A; Thomason, James R

2015-01-01

The ecological significance of fish and squid of the mesopelagic zone (200 m-1000 m) is evident by their pervasiveness in the diets of a broad spectrum of upper pelagic predators including other fishes and squids, seabirds and marine mammals. As diel vertical migrators, mesopelagic micronekton are recognized as an important trophic link between the deep scattering layer and upper surface waters, yet fundamental aspects of the life history and energetic contribution to the food web for most are undescribed. Here, we present newly derived regression equations for 32 species of mesopelagic fish and squid based on the relationship between body size and the size of hard parts typically used to identify prey species in predator diet studies. We describe the proximate composition and energy density of 31 species collected in the eastern Bering Sea during May 1999 and 2000. Energy values are categorized by body size as a proxy for relative age and can be cross-referenced with the derived regression equations. Data are tabularized to facilitate direct application to predator diet studies and food web models.

Trace element concentrations in the top predator jumbo squid (Dosidicus gigas) from the Gulf of California.

PubMed

Raimundo, Joana; Vale, Carlos; Rosa, Rui

2014-04-01

Jumbo (or Humboldt) squid, Dosidicus gigas, is a large jet-propelled top oceanic predator off the Eastern Pacific. The present study reports, for the first time, concentrations of V, Cr, Mn, Co, Ni, Cu, Zn, As, Se, Cd and Pb in gills, mantle and digestive gland of this powerful pelagic squid in the Gulf of California. Zinc and Cu were the most abundant elements. All elements, with the exception of As, were largely stored in digestive gland; particularly Cd that reached concentrations between 57 and 509 µg g(-1). Significant relationships between tissues were found for Co (digestive gland-gills), As (gills-mantle) and Cd (digestive gland-mantle). Proportionality of Cd concentrations between mantle and digestive gland suggested that detoxification capacity by digestive gland was insufficient to avoid the transfer of this element to mantle and other tissues. Nonetheless, Cd concentrations in the mantle were always below the regulatory limit and, therefore lack of constraints for human consumption. On the basis of the fishery landings, one may estimate that up to 1t of Cd can be annually removed by jumbo squid fisheries. Copyright © 2014 Elsevier Inc. All rights reserved.

Prolonged Decline of Jumbo Squid (Dosidicus gigas) Landings in the Gulf of California is Associated with Chronically low wind Stress and Decreased Chlorophyll a after El Niño 2009-2010

NASA Astrophysics Data System (ADS)

Robinson, C. J.; Gomez-Gutierrez, J.

2016-02-01

Dosidicus gigas (jumbo squid) is an ecologically relevant predator in the Gulf of California, Mexico, where it supports an economically valuable fishery. The commercial jumbo squid fishery in the Gulf declined steeply after an El Niño event in 2009-2010, and subsequent landings have remained at historically low levels in the relevant squid fishing centers (Guaymas, Sonora, and Santa Rosalia, Baja California Sur). In this paper, we examined wind speed and satellite chlorophyll a concentrations on the jumbo squid fishing grounds as factors that would be expected to be relevant to this prolonged period of low landings. Analysis from local weather stations, remote sensing and fishery data showed that low jumbo squid landings from 2010 to 2015 occurred during a period abnormally weak winter/spring winds and extremely low chlorophyll a concentrations off the East Guaymas Basin. Results indicate that the squid fishing area in the Guaymas region has been chronically impoverished during this period, and that this area may no longer be a productive habitat for jumbo squid. In response to this decreased productivity, size-at-maturity of jumbo squid showed a drastic decrease over the same period. Results are compared with the effect of El Niño 1997-1998 on the jumbo squid fishery and size-at-maturity of this species in the Gulf of California. The key difference between the recovery phases for El Niño 1997-1998 versus El Niño2009-2010 was the wind intensity as measured in the Guaymas fishing area.

Application of chemical arrays in screening elastase inhibitors.

PubMed

Gao, Feng; Du, Guan-Hua

2006-06-01

Protein chip technology provides a new and useful tool for high-throughput screening of drugs because of its high performance and low sample consumption. In order to screen elastase inhibitors on a large scale, we designed a composite microarray integrating enzyme chip containing chemical arrays on glass slides to screen for enzymatic inhibitors. The composite microarray includes an active proteinase film, screened chemical arrays distributed on the film, and substrate microarrays to demonstrate change of color. The detection principle is that elastase hydrolyzes synthetic colorless substrates and turns them into yellow products. Because yellow is difficult to detect, bromochlorophenol blue (BPB) was added into substrate solutions to facilitate the detection process. After the enzyme had catalyzed reactions for 2 h, effects of samples on enzymatic activity could be determined by detecting color change of the spots. When chemical samples inhibited enzymatic activity, substrates were blue instead of yellow products. If the enzyme retained its activity, the yellow color of the products combined with blue of BPB to make the spots green. Chromogenic differences demonstrated whether chemicals inhibited enzymatic activity or not. In this assay, 11,680 compounds were screened, and two valuable chemical hits were identified, which demonstrates that this assay is effective, sensitive and applicable for high-throughput screening (HTS).

Effect of pulsed ultrasound on the physicochemical characteristics and emulsifying properties of squid (Dosidicus gigas) mantle proteins.

PubMed

Higuera-Barraza, O A; Torres-Arreola, W; Ezquerra-Brauer, J M; Cinco-Moroyoqui, F J; Rodríguez Figueroa, J C; Marquez-Ríos, E

2017-09-01

Food technologists are always looking to improve the functional properties of proteins. In this sense, in last years ultrasound has been used to improve some functional properties. For this reason, and considering that jumbo squid is an important fishery in northwest Mexico, the purpose of this research was to determine the effect of pulsed ultrasound on the physicochemical characteristics and emulsifying properties of squid (Dosidicus gigas) mantle proteins. Pulsed ultrasound (20kHz, 20, and 40% amplitude) was applied for 30, 60, and 90s to a protein extract prepared from giant squid mantle causing an increase (p<0.05) in surface hydrophobicity (S o ) from 108.4±1.4 to 239.1±2.4 after application of pulsed ultrasound at 40% of amplitude for 90s. The electrophoretic profile and the total and reactive sulfhydryl contents were not affected (p⩾0.05) by the ultrasound treatment. The emulsifying ability of the protein solution was improved (p<0.05), whereas the Emulsifier Activity Index (EAI) varied from123.67±5.52m 2 /g for the control and increased up to 217.7±3.8m 2 /g after application of the ultrasound. The Stability Emulsifier Index (EEI) was improved at 40% of amplitude by 60 and 90s. The results suggested that pulsed ultrasound used as pretreatment induced conformational changes in giant squid proteins, which improved the interfacial association between protein-oil phases, thus contributing to the improvement of their emulsifient properties. Copyright © 2017 Elsevier B.V. All rights reserved.

Progress of applied superconductivity research at Materials Research Laboratories, ITRI (Taiwan)

NASA Technical Reports Server (NTRS)

Liu, R. S.; Wang, C. M.

1995-01-01

A status report based on the applied high temperature superconductivity (HTS) research at Materials Research Laboratories (MRL), Industrial Technology Research Institute (ITRI) is given. The aim is to develop fabrication technologies for the high-TC materials appropriate to the industrial application requirements. To date, the majorities of works have been undertaken in the areas of new materials, wires/tapes with long length, prototypes of magnets, large-area thin films, SQUID's and microwave applications.

A 20-channel magnetoencephalography system based on optically pumped magnetometers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borna, Amir; Carter, Tony R.; Goldberg, Josh D.

In this paper, we describe a multichannel magnetoencephalography (MEG) system that uses optically pumped magnetometers (OPMs) to sense the magnetic fields of the human brain. The system consists of an array of 20 OPM channels conforming to the human subject's head, a person-sized magnetic shield containing the array and the human subject, a laser system to drive the OPM array, and various control and data acquisition systems. We conducted two MEG experiments: auditory evoked magnetic field and somatosensory evoked magnetic field, on three healthy male subjects, using both our OPM array and a 306-channel Elekta-Neuromag superconducting quantum interference device (SQUID)more » MEG system. The described OPM array measures the tangential components of the magnetic field as opposed to the radial component measured by most SQUID-based MEG systems. Finally, herein, we compare the results of the OPM- and SQUID-based MEG systems on the auditory and somatosensory data recorded in the same individuals on both systems.« less

A 20-channel magnetoencephalography system based on optically pumped magnetometers

DOE PAGES

Borna, Amir; Carter, Tony R.; Goldberg, Josh D.; ...

2017-10-16

In this paper, we describe a multichannel magnetoencephalography (MEG) system that uses optically pumped magnetometers (OPMs) to sense the magnetic fields of the human brain. The system consists of an array of 20 OPM channels conforming to the human subject's head, a person-sized magnetic shield containing the array and the human subject, a laser system to drive the OPM array, and various control and data acquisition systems. We conducted two MEG experiments: auditory evoked magnetic field and somatosensory evoked magnetic field, on three healthy male subjects, using both our OPM array and a 306-channel Elekta-Neuromag superconducting quantum interference device (SQUID)more » MEG system. The described OPM array measures the tangential components of the magnetic field as opposed to the radial component measured by most SQUID-based MEG systems. Finally, herein, we compare the results of the OPM- and SQUID-based MEG systems on the auditory and somatosensory data recorded in the same individuals on both systems.« less

A 20-channel magnetoencephalography system based on optically pumped magnetometers

NASA Astrophysics Data System (ADS)

Borna, Amir; Carter, Tony R.; Goldberg, Josh D.; Colombo, Anthony P.; Jau, Yuan-Yu; Berry, Christopher; McKay, Jim; Stephen, Julia; Weisend, Michael; Schwindt, Peter D. D.

2017-12-01

We describe a multichannel magnetoencephalography (MEG) system that uses optically pumped magnetometers (OPMs) to sense the magnetic fields of the human brain. The system consists of an array of 20 OPM channels conforming to the human subject’s head, a person-sized magnetic shield containing the array and the human subject, a laser system to drive the OPM array, and various control and data acquisition systems. We conducted two MEG experiments: auditory evoked magnetic field and somatosensory evoked magnetic field, on three healthy male subjects, using both our OPM array and a 306-channel Elekta-Neuromag superconducting quantum interference device (SQUID) MEG system. The described OPM array measures the tangential components of the magnetic field as opposed to the radial component measured by most SQUID-based MEG systems. Herein, we compare the results of the OPM- and SQUID-based MEG systems on the auditory and somatosensory data recorded in the same individuals on both systems.

Predictive Signatures of Developmental Toxicity Modeled with HTS Data from ToxCast™ Bioactivity Profiles

EPA Science Inventory

The EPA ToxCast™ research program uses a high-throughput screening (HTS) approach for predicting the toxicity of large numbers of chemicals. Phase-I contains 309 well-characterized chemicals which are mostly pesticides tested in over 600 assays of different molecular targets, cel...

Design, Test and Demonstration of Fault Current Limiting HTS Transformer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hazelton, Drew

The project developed new technology that enables the creation of a high temperature superconductor-based FCL power transformer. SuperPower’s research and development created new methods to bond HTS conductor to a supporting substrate, test, and insulate the resulting bonded conductor, reduce winding ac losses, ensure FCL functionality during a transformer fault and build firm superconducting joints in the transformer harnesses and cabling. The bonded conductor in this program was shown to meet the critical operating parameters of providing the superconducting transformer operation while being able to meet the target normal state resistance required for FCL operation. The bonded conductor was alsomore » shown to be able to handle the fabrication stresses associated with the manufacture of the FCL transformer while also being able to handle the high hoop stresses and axial forces during a fault transient. Much of the technology developed here is applicable to the broader applied superconductivity community. The ability to tailor the clad conductors performance characteristics gives the designer of devices utilizing HTS a broader capability to address the particular needs of an given application. SuperPower worked with its sub-recipients Waukesha Electric Systems, ORNL, Southern California Edison and University of Houston to develop the design, fabrication, installation and operational aspects of a fault current limiting transformer on the electrical grid.« less

Mixed cryogen cooling systems for HTS power applications: A status report of progress in Korea University

NASA Astrophysics Data System (ADS)

Song, Jung-Bin; Lee, Haigun

2012-12-01

A cooling system employing a solid cryogen (SC), such as solid nitrogen (SN2), was recently reported for high-temperature superconducting (HTS) applications. However, thermal contact between the SC and the HTS can be degraded by repeated overcurrent runs, resulting in 'thermal dry-out'. Novel cryogens, SC with small amounts of liquid cryogen, have been suggested to overcome this problem. Such cooling systems rely on the small amount of liquid cryogen to facilitate heat exchange so as to fully exploit the heat capacity of the solid cryogen. This paper presents a description and summary of recent activities at Korea University related to cooling systems employing mixed cryogens of solid-liquid nitrogen, solid argon-liquid nitrogen, and solid nitrogen-liquid neon.

Vertically aligned carbon nanotube arrays as thermal interface material for vibrational structure of piezoelectric transformer

NASA Astrophysics Data System (ADS)

Chen, Lie; Ju, Bin; Feng, Zhihua; Zhao, Yang

2018-07-01

The application and characterization of thermal interface material (TIM) for vibrational structures is investigated in this paper. The vibrating feature during the operation requires unique solution for its thermal management, since the connection between the device and heat dissipater should be able to conduct heat efficiently and impose minimum constraint onto the vibration simultaneously. As a typical vibrational device, piezoelectric transformers (PTs) are discussed in this paper. The PTs have urgent demands for thermal dissipation since their power conversion efficiency decrease rapidly with the rising temperature. A novel method by applying vertically aligned carbon nanotube (VACNT) arrays to the interface between PT and heat dissipater is presented to enhance the performance of piezoelectric transformers. VACNT arrays are one of the excellent TIMs. It can directly establish thermal contact between two surfaces by van der Waals’ forces. In addition, the unique anisotropic character of CNT arrays provides enough flexibility to accommodate the vibration during the operation. Different configurations of TIMs are compared with each other in this work, including CNT arrays, tape of polypropylene (PP) membrane and without heat transfer structure (HTS). The results indicate that the temperature rise is lowest and the efficiency is highest at the same power density while CNT arrays served as the TIM. Almost no significant fretting and wearing damage occurred on PT electrode surface with CNT arrays TIM even after working continuously for 120 days. Meanwhile, the thermo-physical properties of CNT arrays at contact interface are measured by optical transient thermo-reflectance technique.

Model of Auctioneer Estimation of Swordtip Squid (Loligo edulis) Quality

NASA Astrophysics Data System (ADS)

Nakamura, Makoto; Matsumoto, Keisuke; Morimoto, Eiji; Ezoe, Satoru; Maeda, Toshimichi; Hirano, Takayuki

The knowledge of experienced auctioneers regarding the circulation of marine products is an essential skill and is necessary for evaluating product quality and managing aspects such as freshness. In the present study, the ability of an auctioneer to quickly evaluate the freshness of swordtip squid (Loligo edulis) at fish markets was analyzed. Evaluation characteristics used by an auctioneer were analyzed and developed using a fuzzy logic model. Forty boxes containing 247 swordtip squid with mantles measuring 220 mm that had been evaluated and assigned to one of five quality categories by an auctioneer were used for the analysis and the modeling. The relationships between the evaluations of appearance, body color, and muscle freshness were statistically analyzed. It was found that a total of four indexes of the epidermis color strongly reflected evaluations of appearance: dispersion ratio of the head, chroma on the head-end mantle and the difference in the chroma and brightness of the mantle. The fuzzy logic model used these indexes for the antecedent-part of the linguistic rules. The results of both simulation and evaluations demonstrate that the model is robust, with the predicted results corresponding with more than 96% of the quality assignments of the auctioneers.

Numerical models of delamination behavior in 2G HTS tapes under transverse tension and peel

NASA Astrophysics Data System (ADS)

Duan, Yujie; Ta, Wurui; Gao, Yuanwen

2018-02-01

In extreme operating environments, delamination in 2G HTS tapes occurs within and/or near the superconductor layer from high transverse tensile stresses caused by fabrication, Lorentz forces and thermal mismatch, etc. Generally, transverse opening and peeling off are the main delamination modes, and are always studied in anvil and peel tests, respectively. Numerical models of these modes for 2G HTS tape are presented wherein the mixed-mode traction-separation law at the interface of the silver and superconductor layers is considered. Plastic deformations of copper, silver, and Hastelloy® in the HTS tape are taken into account. The results obtained from the transverse opening model show that the maximum average tensile stress is smaller than the delamination tensile strength because delamination is asynchronous in the tape. When a crack appears in the tape, only a small stress ( ≤ 1 MPa) is required to expand the crack to other stress free areas through peeling. Using the peeling model, the dependency of the peel strength on peeling angle is investigated under constant fracture toughness. Peel strength decreases with the peeling angle until the minimum value is reached at 150°, and thereafter increases slightly. Other results indicate that peel strength depends strongly on delamination strength, fracture toughness, and thickness of copper layer. The fracture toughness of the delamination interface, which is difficult to obtain by experiment, can be extracted using the present model.

Production and functional evaluation of a protein concentrate from giant squid (Dosidicus gigas) by acid dissolution and isoelectric precipitation.

PubMed

Cortés-Ruiz, Juan A; Pacheco-Aguilar, Ramón; Elena Lugo-Sánchez, M; Gisela Carvallo-Ruiz, M; García-Sánchez, Guillermina

2008-09-15

A protein concentrate from giant squid (Dosidicus gigas) was produced under acidic conditions and its functional-technological capability evaluated in terms of its gel-forming ability, water holding capacity and colour attributes. Technological functionality of the concentrate was compared with that of squid muscle and a neutral concentrate. Protein-protein aggregates insoluble at high ionic strength (I=0.5M), were detected in the acidic concentrate as result of processing with no preclusion of its gel-forming ability during the sol-to-gel thermal transition. Even though washing under acidic condition promoted autolysis of the myosin heavy chain, the acidic concentrate displayed an outstanding ability to gel giving samples with a gel strength of 455 and 1160gcm at 75% and 90% compression respectively, and an AA folding test grade indicative of high gel strength, elasticity, and cohesiveness. The process proved to be a good alternative for obtaining a functional protein concentrate from giant squid muscle. Copyright © 2008. Published by Elsevier Ltd.

Material Structure of a Graded Refractive Index Lens in Decapod Squid

NASA Astrophysics Data System (ADS)

Cai, Jing; Heiney, Paul; Sweeney, Alison

2013-03-01

Underwater vision with a camera-type eye that is simultaneously acute and sensitive requires a spherical lens with a graded distribution of refractive index. Squids have this type of lens, and our previous work has shown that its optical properties are likely achieved with radially variable densities of a single protein with multiple isoforms. Here we measure the spatial organization of this novel protein material in concentric layers of the lens and use these data to suggest possible mechanisms of self-assembly of the proteins into a graded refractive index structure. First, we performed small angle x-ray scattering (SAXS) to study how the protein is spatially organized. Then, molecular dynamic simulation allowed us to correlate structure to the possible dynamics of the system in different regions of the lens. The combination of simulation and SAXS data in this system revealed the likely protein-protein interactions, resulting material structure and its relationship to the observed and variable optical properties of this graded index system. We believe insights into the material properties of the squid lens system will inform the invention of self-assembling graded index devices.

Variability of Suitable Habitat of Western Winter-Spring Cohort for Neon Flying Squid in the Northwest Pacific under Anomalous Environments

PubMed Central

Yu, Wei; Chen, Xinjun; Yi, Qian; Chen, Yong; Zhang, Yang

2015-01-01

We developed a habitat suitability index (HSI) model to evaluate the variability of suitable habitat for neon flying squid (Ommastrephes bartramii) under anomalous environments in the Northwest Pacific Ocean. Commercial fisheries data from the Chinese squid-jigging vessels on the traditional fishing ground bounded by 35°-45°N and 150°-175°E from July to November during 1998-2009 were used for analyses, as well as the environmental variables including sea surface temperature (SST), chlorophyll-a (Chl-a) concentration, sea surface height anomaly (SSHA) and sea surface salinity (SSS). Two empirical HSI models (arithmetic mean model, AMM; geometric mean model, GMM) were established according to the frequency distribution of fishing efforts. The AMM model was found to perform better than the GMM model. The AMM-based HSI model was further validated by the fishery and environmental data in 2010. The predicted HSI values in 1998 (high catch), 2008 (average catch) and 2009 (low catch) indicated that the squid habitat quality was strongly associated with the ENSO-induced variability in the oceanic conditions on the fishing ground. The La Niña events in 1998 tended to yield warm SST and favorable range of Chl-a concentration and SSHA, resulting in high-quality habitats for O. bartramii. While the fishing ground in the El Niño year of 2009 experienced anomalous cool waters and unfavorable range of Chl-a concentration and SSHA, leading to relatively low-quality squid habitats. Our findings suggest that the La Niña event in 1998 tended to result in more favorable habitats for O. bartramii in the Northwest Pacific with the gravity centers of fishing efforts falling within the defined suitable habitat and yielding high squid catch; whereas the El Niño event in 2009 yielded less favorable habitat areas with the fishing effort distribution mismatching the suitable habitat and a dramatic decline of the catch of O. bartramii. This study might provide some potentially valuable

Analysis of transient state in HTS tapes under ripple DC load current

NASA Astrophysics Data System (ADS)

Stepien, M.; Grzesik, B.

2014-05-01

The paper concerns the analysis of transient state (quench transition) in HTS tapes loaded with the current having DC component together with a ripple component. Two shapes of the ripple were taken into account: sinusoidal and triangular. Very often HTS tape connected to a power electronic current supply (i.e. superconducting coil for SMES) that delivers DC current with ripples and it needs to be examined under such conditions. Additionally, measurements of electrical (and thermal) parameters under such ripple excitation is useful to tape characterization in broad range of load currents. The results presented in the paper were obtained using test bench which contains programmable DC supply and National Instruments data acquisition system. Voltage drops and load currents were measured vs. time. Analysis of measured parameters as a function of the current was used to tape description with quench dynamics taken into account. Results of measurements were also used to comparison with the results of numerical modelling based on FEM. Presented provisional results show possibility to use results of measurements in transient state to prepare inverse models of superconductors and their detailed numerical modelling.

Testing of machine wound second generation HTS tape Vacuum Pressure Impregnated coils

NASA Astrophysics Data System (ADS)

Swaffield, D.; Lewis, C.; Eugene, J.; Ingles, M.; Peach, D.

2014-05-01

Delamination of second generation (2G) High Temperature Superconducting (HTS) tapes has previously been reported when using resin based insulation systems for wound coils. One proposed root cause is the differential thermal contraction between the coil former and the resin encapsulated coil turns resulting in the tape c-axis tensile stress being exceeded. Importantly, delamination results in unacceptable degradation of the superconductor critical current level. To mitigate the delamination risk and prove winding, jointing and Vacuum Pressure Impregnation (VPI) processes in the production of coils for superconducting rotating machines at GE Power Conversion two scaled trial coils have been wound and extensively tested. The coils are wound from 12mm wide 2G HTS tape supplied by AMSC onto stainless steel 'racetrack' coil formers. The coils are wound in two layers which include both in-line and layer-layer joints subject to in-process test. The resin insulation system chosen is VPI and oven cured. Tests included; insulation resistance, repeat quench and recovery of the superconductor, heat runs and measurement of n-value, before and after multiple thermal cycling between ambient and 35 Kelvin. No degradation of coil performance is evidenced.

First in situ observations of the deep-sea squid Grimalditeuthis bonplandi reveal unique use of tentacles

PubMed Central

Hoving, Hendrik J. T.; Zeidberg, Louis D.; Benfield, Mark C.; Bush, Stephanie L.; Robison, Bruce H.; Vecchione, Michael

2013-01-01

The deep-sea squid Grimalditeuthis bonplandi has tentacles unique among known squids. The elastic stalk is extremely thin and fragile, whereas the clubs bear no suckers, hooks or photophores. It is unknown whether and how these tentacles are used in prey capture and handling. We present, to our knowledge, the first in situ observations of this species obtained by remotely operated vehicles (ROVs) in the Atlantic and North Pacific. Unexpectedly, G. bonplandi is unable to rapidly extend and retract the tentacle stalk as do other squids, but instead manoeuvres the tentacles by undulation and flapping of the clubs’ trabecular protective membranes. These tentacle club movements superficially resemble the movements of small marine organisms and suggest the possibility that G. bonplandi uses aggressive mimicry by the tentacle clubs to lure prey, which we find to consist of crustaceans and cephalopods. In the darkness of the meso- and bathypelagic zones the flapping and undulatory movements of the tentacle may: (i) stimulate bioluminescence in the surrounding water, (ii) create low-frequency vibrations and/or (iii) produce a hydrodynamic wake. Potential prey of G. bonplandi may be attracted to one or more of these as signals. This singular use of the tentacle adds to the diverse foraging and feeding strategies known in deep-sea cephalopods. PMID:23986106

Effect of stimulation and hyperpolarization on non-electrolyte and sodium permeability in perfused axons of squid.

PubMed

Hidalgo, C; Latorre, R

1970-11-01

1. The permeability for micro-injected [(3)H]ethylene glycol was measured in resting state and during stimulation at 100/sec in squid giant axons. No detectable changes during electrical activity were observed.2. The influxes of urethane, tritiated water, ethylene glycol, urea and sodium were measured in internally perfused squid axons. Ethylene glycol and urea influxes were determined simultaneously with sodium influxes. The electrical stimulation of the fibre produced an increase in the influx of sodium but did not alter the influxes of the non-electrolytes listed above.3. Experiments were done with the combined voltage clamp-perfusion technique. The influxes of ethylene glycol and sodium were simultaneously measured in resting state and during maximum sodium current under stimulation at 10/sec. The influx of sodium increased in these conditions but the influx of ethylene glycol remained constant. In some experiments, the fibre was hyperpolarized to 10 or 20 mV, above the resting potential and the influxes of ethylene glycol and sodium were measured. The sodium influx decreased to 60% at 20 mV above the resting potential whereas the influx of ethylene glycol remained constant.4. These results indicate that in the giant axons of the squid Dosidicus gigas, sodium and non-electrolytes fluxes are not coupled.

Effect of stimulation and hyperpolarization on non-electrolyte and sodium permeability in perfused axons of squid

PubMed Central

Hidalgo, Cecilia; Latorre, Ramón

1970-01-01

1. The permeability for micro-injected [3H]ethylene glycol was measured in resting state and during stimulation at 100/sec in squid giant axons. No detectable changes during electrical activity were observed. 2. The influxes of urethane, tritiated water, ethylene glycol, urea and sodium were measured in internally perfused squid axons. Ethylene glycol and urea influxes were determined simultaneously with sodium influxes. The electrical stimulation of the fibre produced an increase in the influx of sodium but did not alter the influxes of the non-electrolytes listed above. 3. Experiments were done with the combined voltage clamp—perfusion technique. The influxes of ethylene glycol and sodium were simultaneously measured in resting state and during maximum sodium current under stimulation at 10/sec. The influx of sodium increased in these conditions but the influx of ethylene glycol remained constant. In some experiments, the fibre was hyperpolarized to 10 or 20 mV, above the resting potential and the influxes of ethylene glycol and sodium were measured. The sodium influx decreased to 60% at 20 mV above the resting potential whereas the influx of ethylene glycol remained constant. 4. These results indicate that in the giant axons of the squid Dosidicus gigas, sodium and non-electrolytes fluxes are not coupled. PMID:5500991

50 CFR 648.25 - Atlantic Mackerel, squid, and butterfish framework adjustments to management measures.

Code of Federal Regulations, 2012 CFR

2012-10-01

... framework adjustments to management measures. 648.25 Section 648.25 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE FISHERIES... Butterfish Fisheries § 648.25 Atlantic Mackerel, squid, and butterfish framework adjustments to management...

50 CFR 648.25 - Atlantic Mackerel, squid, and butterfish framework adjustments to management measures.

Code of Federal Regulations, 2014 CFR

2014-10-01

... framework adjustments to management measures. 648.25 Section 648.25 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE FISHERIES... Butterfish Fisheries § 648.25 Atlantic Mackerel, squid, and butterfish framework adjustments to management...

50 CFR 648.25 - Atlantic Mackerel, squid, and butterfish framework adjustments to management measures.

Code of Federal Regulations, 2013 CFR

2013-10-01

... framework adjustments to management measures. 648.25 Section 648.25 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE FISHERIES... Butterfish Fisheries § 648.25 Atlantic Mackerel, squid, and butterfish framework adjustments to management...

Projected near-future CO2 levels increase activity and alter defensive behaviours in the tropical squid Idiosepius pygmaeus

PubMed Central

Spady, Blake L.; Watson, Sue-Ann; Chase, Tory J.; Munday, Philip L.

2014-01-01

ABSTRACT Carbon dioxide (CO2) levels projected to occur in the oceans by the end of this century cause a range of behavioural effects in fish, but whether other highly active marine organisms, such as cephalopods, are similarly affected is unknown. We tested the effects of projected future CO2 levels (626 and 956 µatm) on the behaviour of male two-toned pygmy squid, Idiosepius pygmaeus. Exposure to elevated CO2 increased the number of active individuals by 19–25% and increased movement (number of line-crosses) by nearly 3 times compared to squid at present-day CO2. Squid vigilance and defensive behaviours were also altered by elevated CO2 with >80% of individuals choosing jet escape responses over defensive arm postures in response to a visual startle stimulus, compared with 50% choosing jet escape responses at control CO2. In addition, more escape responses were chosen over threat behaviours in body pattern displays at elevated CO2 and individuals were more than twice as likely to use ink as a defence strategy at 956 µatm CO2, compared with controls. Increased activity could lead to adverse effects on energy budgets as well as increasing visibility to predators. A tendency to respond to a stimulus with escape behaviours could increase survival, but may also be energetically costly and could potentially lead to more chases by predators compared with individuals that use defensive postures. These results demonstrate that projected future ocean acidification affects the behaviours of a tropical squid species. PMID:25326517

Advanced ACTPol Low-Frequency Array: Readout and Characterization of Prototype 27 and 39 GHz Transition Edge Sensors

NASA Astrophysics Data System (ADS)

Koopman, B. J.; Cothard, N. F.; Choi, S. K.; Crowley, K. T.; Duff, S. M.; Henderson, S. W.; Ho, S. P.; Hubmayr, J.; Gallardo, P. A.; Nati, F.; Niemack, M. D.; Simon, S. M.; Staggs, S. T.; Stevens, J. R.; Vavagiakis, E. M.; Wollack, E. J.

2018-05-01

Advanced ACTPol (AdvACT) is a third-generation polarization upgrade to the Atacama Cosmology Telescope, designed to observe the cosmic microwave background (CMB). AdvACT expands on the 90 and 150 GHz transition edge sensor (TES) bolometer arrays of the ACT Polarimeter (ACTPol), adding both high-frequency (HF, 150/230 GHz) and low-frequency (LF, 27/39 GHz) multichroic arrays. The addition of the high- and low-frequency detectors allows for the characterization of synchrotron and spinning dust emission at the low frequencies and foreground emission from galactic dust and dusty star-forming galaxies at the high frequencies. The increased spectral coverage of AdvACT will enable a wide range of CMB science, such as improving constraints on dark energy, the sum of the neutrino masses, and the existence of primordial gravitational waves. The LF array will be the final AdvACT array, replacing one of the MF arrays for a single season. Prior to the fabrication of the final LF detector array, we designed and characterized prototype TES bolometers. Detector geometries in these prototypes are varied in order to inform and optimize the bolometer designs for the LF array, which requires significantly lower noise levels and saturation powers (as low as {˜ } 1 pW) than the higher-frequency detectors. Here we present results from tests of the first LF prototype TES detectors for AdvACT, including measurements of the saturation power, critical temperature, thermal conductance, and time constants. We also describe the modifications to the time-division SQUID readout architecture compared to the MF and HF arrays.

Extraction and characterization of collagen from Antarctic and Sub-Antarctic squid and its potential application in hybrid scaffolds for tissue engineering.

PubMed

Coelho, Rui C G; Marques, Ana L P; Oliveira, Sara M; Diogo, Gabriela S; Pirraco, Rogério P; Moreira-Silva, Joana; Xavier, José C; Reis, Rui L; Silva, Tiago H; Mano, João F

2017-09-01

Collagen is the most abundant protein found in mammals and it exhibits a low immunogenicity, high biocompatibility and biodegradability when compared with others natural polymers. For this reason, it has been explored for the development of biologically instructive biomaterials with applications for tissue substitution and regeneration. Marine origin collagen has been pursued as an alternative to the more common bovine and porcine origins. This study focused on squid (Teuthoidea: Cephalopoda), particularly the Antarctic squid Kondakovia longimana and the Sub-Antarctic squid Illex argentinus as potential collagen sources. In this study, collagen has been isolated from the skins of the squids using acid-based and pepsin-based protocols, with the higher yield being obtained from I. argentinus in the presence of pepsin. The produced collagen has been characterized in terms of physicochemical properties, evidencing an amino acid profile similar to the one of calf collagen, but exhibiting a less preserved structure, with hydrolyzed portions and a lower melting temperature. Pepsin-soluble collagen isolated from I. argentinus was selected for further evaluation of biomedical potential, exploring its incorporation on poly-ε-caprolactone (PCL) 3D printed scaffolds for the development of hybrid scaffolds for tissue engineering, exhibiting hierarchical features. Copyright © 2017 Elsevier B.V. All rights reserved.

Commercial squids: characterization, assessment of potential health benefits/risks and discrimination based on mineral, lipid and vitamin E concentrations.

PubMed

Torrinha, A; Gomes, F; Oliveira, M; Cruz, R; Mendes, E; Delerue-Matos, C; Casal, S; Morais, S

2014-05-01

The most consumed squid species worldwide were characterized regarding their concentrations of minerals, fatty acids, cholesterol and vitamin E. Interspecific comparisons were assessed among species and geographical origin. The health benefits derived from squid consumption were assessed based on daily minerals intake and on nutritional lipid quality indexes. Squids contribute significantly to daily intake of several macro (Na, K, Mg and P) and micronutrients (Cu, Zn and Ni). Despite their low fat concentration, they are rich in long-chain omega-3 fatty acids, particularly docosahexaenoic (DHA) and eicosapentanoic (EPA) acids, with highly favorable ω-3/ω-6 ratios (from 5.7 to 17.7), reducing the significance of their high cholesterol concentration (140-549 mg/100g ww). Assessment of potential health risks based on minerals intake, non-carcinogenic and carcinogenic risks indicated that Loligo gahi (from Atlantic Ocean), Loligo opalescens (from Pacific Ocean) and Loligo duvaucelii (from Indic Ocean) should be eaten with moderation due to the high concentrations of Cu and/or Cd. Canonical discriminant analysis identified the major fatty acids (C14:0, C18:0, C18:1, C18:3ω-3, C20:4ω-6 and C22:5ω-6), P, K, Cu and vitamin E as chemical discriminators for the selected species. These elements and compounds exhibited the potential to prove authenticity of the commercially relevant squid species. Copyright © 2014 Elsevier Ltd. All rights reserved.

Muscular tissues of the squid Doryteuthis pealeii express identical myosin heavy chain isoforms: an alternative mechanism for tuning contractile speed

PubMed Central

Shaffer, Justin F.; Kier, William M.

2012-01-01

SUMMARY The speed of muscle contraction is largely controlled at the sarcomere level by the ATPase activity of the motor protein myosin. Differences in amino acid sequence in catalytically important regions of myosin yield different myosin isoforms with varying ATPase activities and resulting differences in cross-bridge cycling rates and interfilamentary sliding velocities. Modulation of whole-muscle performance by changes in myosin isoform ATPase activity is regarded as a universal mechanism to tune contractile properties, especially in vertebrate muscles. Invertebrates such as squid, however, may exhibit an alternative mechanism to tune contractile properties that is based on differences in muscle ultrastructure, including variable myofilament and sarcomere lengths. To determine definitively whether contractile properties of squid muscles are regulated via different myosin isoforms (i.e. different ATPase activities), the nucleotide and amino acid sequences of the myosin heavy chain from the squid Doryteuthis pealeii were determined from the mantle, arm, tentacle, fin and funnel retractor musculature. We identified three myosin heavy chain isoforms in squid muscular tissues, with differences arising at surface loop 1 and the carboxy terminus. All three isoforms were detected in all five tissues studied. These results suggest that the muscular tissues of D. pealeii express identical myosin isoforms, and it is likely that differences in muscle ultrastructure, not myosin ATPase activity, represent the most important mechanism for tuning contractile speeds. PMID:22189767

The Emory Chemical Biology Discovery Center: leveraging academic innovation to advance novel targets through HTS and beyond.

PubMed

Johns, Margaret A; Meyerkord-Belton, Cheryl L; Du, Yuhong; Fu, Haian

2014-03-01

The Emory Chemical Biology Discovery Center (ECBDC) aims to accelerate high throughput biology and translation of biomedical research discoveries into therapeutic targets and future medicines by providing high throughput research platforms to scientific collaborators worldwide. ECBDC research is focused at the interface of chemistry and biology, seeking to fundamentally advance understanding of disease-related biology with its HTS/HCS platforms and chemical tools, ultimately supporting drug discovery. Established HTS/HCS capabilities, university setting, and expertise in diverse assay formats, including protein-protein interaction interrogation, have enabled the ECBDC to contribute to national chemical biology efforts, empower translational research, and serve as a training ground for young scientists. With these resources, the ECBDC is poised to leverage academic innovation to advance biology and therapeutic discovery.

Bacterial bioluminescence regulates expression of a host cryptochrome gene in the squid-Vibrio symbiosis.

PubMed

Heath-Heckman, Elizabeth A C; Peyer, Suzanne M; Whistler, Cheryl A; Apicella, Michael A; Goldman, William E; McFall-Ngai, Margaret J

2013-04-02

The symbiosis between the squid Euprymna scolopes and its luminous symbiont, Vibrio fischeri, is characterized by daily transcriptional rhythms in both partners and daily fluctuations in symbiont luminescence. In this study, we sought to determine whether symbionts affect host transcriptional rhythms. We identified two transcripts in host tissues (E. scolopes cry1 [escry1] and escry2) that encode cryptochromes, proteins that influence circadian rhythms in other systems. Both genes cycled daily in the head of the squid, with a pattern similar to that of other animals, in which expression of certain cry genes is entrained by environmental light. In contrast, escry1 expression cycled in the symbiont-colonized light organ with 8-fold upregulation coincident with the rhythms of bacterial luminescence, which are offset from the day/night light regime. Colonization of the juvenile light organ by symbionts was required for induction of escry1 cycling. Further, analysis with a mutant strain defective in light production showed that symbiont luminescence is essential for cycling of escry1; this defect could be complemented by presentation of exogenous blue light. However, blue-light exposure alone did not induce cycling in nonsymbiotic animals, but addition of molecules of the symbiont cell envelope to light-exposed animals did recover significant cycling activity, showing that light acts in synergy with other symbiont features to induce cycling. While symbiont luminescence may be a character specific to rhythms of the squid-vibrio association, resident microbial partners could similarly influence well-documented daily rhythms in other systems, such as the mammalian gut.

Digitally controlled high-performance dc SQUID readout electronics for a 304-channel vector magnetometer

NASA Astrophysics Data System (ADS)

Bechstein, S.; Petsche, F.; Scheiner, M.; Drung, D.; Thiel, F.; Schnabel, A.; Schurig, Th

2006-06-01

Recently, we have developed a family of dc superconducting quantum interference device (SQUID) readout electronics for several applications. These electronics comprise a low-noise preamplifier followed by an integrator, and an analog SQUID bias circuit. A highly-compact low-power version with a flux-locked loop bandwidth of 0.3 MHz and a white noise level of 1 nV/√Hz was specially designed for a 304-channel low-Tc dc SQUID vector magnetometer, intended to operate in the new Berlin Magnetically Shielded Room (BMSR-2). In order to minimize the space needed to mount the electronics on top of the dewar and to minimize the power consumption, we have integrated four electronics channels on one 3 cm × 10 cm sized board. Furthermore we embedded the analog components of these four channels into a digitally controlled system including an in-system programmable microcontroller. Four of these integrated boards were combined to one module with a size of 4 cm × 4 cm × 16 cm. 19 of these modules were implemented, resulting in a total power consumption of about 61 W. To initialize the 304 channels and to service the system we have developed software tools running on a laptop computer. By means of these software tools the microcontrollers are fed with all required data such as the working points, the characteristic parameters of the sensors (noise, voltage swing), or the sensor position inside of the vector magnetometer system. In this paper, the developed electronics including the software tools are described, and first results are presented.

Dimorphic ejaculates and sperm release strategies associated with alternative mating behaviors in the squid.

PubMed

Apostólico, Lígia H; Marian, José E A R

2017-11-01

Sperm competition is a powerful postcopulatory selective force influencing male adaptations associated with increasing fertilization success, and it is usually related to the evolution of different strategies of ejaculate expenditure between individuals. Ejaculates may also be influenced by additional selective pressures associated with sperm competition, such as timing between insemination and fertilization, female reproductive tract morphology, and fertilization environment. Also, males that adopt alternative mating tactics may face distinct sperm competition pressures, which may lead to the evolution of intraspecific diversity in ejaculates. In loliginid squids, males with alternative reproductive tactics (sneakers and consorts) differ not only in mating behavior, but also transfer spermatophores into two distinct sites within the female. Here, we compared structure and functioning of spermatophores between sneakers and consorts in the squid Doryteuthis plei applying microscopy techniques and in vitro experiments. Sneakers and consorts exhibit differences in spermatophore structure that lead to distinct spermatophoric reactions and spermatangium morphologies. Moreover, in sneakers, sperm release lasts longer and their sperm show an aggregative behavior not detected in consorts. Slow sperm release may be a strategy to guarantee longer sperm provision, given the wide interval between sneaker mating and egg release. For consorts, in turn, intense and quick sperm discharge may be advantageous, as timing between mating and egg-laying is relatively short. Within the complex squid mating system, factors such as (i) different fertilization sites and (ii) interval between mating and egg release may also influence sperm competition, and ultimately shape the evolution of divergent ejaculates between dimorphic males. © 2017 Wiley Periodicals, Inc.

Bacterial Bioluminescence Regulates Expression of a Host Cryptochrome Gene in the Squid-Vibrio Symbiosis

PubMed Central

Heath-Heckman, Elizabeth A. C.; Peyer, Suzanne M.; Whistler, Cheryl A.; Apicella, Michael A.; Goldman, William E.; McFall-Ngai, Margaret J.

2013-01-01

ABSTRACT The symbiosis between the squid Euprymna scolopes and its luminous symbiont, Vibrio fischeri, is characterized by daily transcriptional rhythms in both partners and daily fluctuations in symbiont luminescence. In this study, we sought to determine whether symbionts affect host transcriptional rhythms. We identified two transcripts in host tissues (E. scolopes cry1 [escry1] and escry2) that encode cryptochromes, proteins that influence circadian rhythms in other systems. Both genes cycled daily in the head of the squid, with a pattern similar to that of other animals, in which expression of certain cry genes is entrained by environmental light. In contrast, escry1 expression cycled in the symbiont-colonized light organ with 8-fold upregulation coincident with the rhythms of bacterial luminescence, which are offset from the day/night light regime. Colonization of the juvenile light organ by symbionts was required for induction of escry1 cycling. Further, analysis with a mutant strain defective in light production showed that symbiont luminescence is essential for cycling of escry1; this defect could be complemented by presentation of exogenous blue light. However, blue-light exposure alone did not induce cycling in nonsymbiotic animals, but addition of molecules of the symbiont cell envelope to light-exposed animals did recover significant cycling activity, showing that light acts in synergy with other symbiont features to induce cycling. While symbiont luminescence may be a character specific to rhythms of the squid-vibrio association, resident microbial partners could similarly influence well-documented daily rhythms in other systems, such as the mammalian gut. PMID:23549919