Sample records for human development special
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-15
... National Institute of Child Health & Human Development; Notice of Closed Meetings Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Pharmacokinetics and... . Name of Committee: National Institute of Child Health and Human Development Special Emphasis Panel, HIV...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-06-20
... National Institute of Child Health & Human Development; Notice of Meeting Pursuant to section 10(d) of the... who plan to attend and need special assistance, such as sign language interpretation or other... Committee: National Institute of Child Health and Human Development Special Emphasis Panel; Cardio-metabolic...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-19
... National Institute of Child Health & Human Development; Notice of Meeting Pursuant to section 10(d) of the... who plan to attend and need special assistance, such as sign language interpretation or other... Committee: National Institute of Child Health and Human Development Special Emphasis Panel; Newborn...
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Leadership Training for Special Educators.
ERIC Educational Resources Information Center
Berkeley, Terry R.; And Others
This paper describes a leadership model based on assumptions about connections between human development and organizational development, and the application of the model in leadership training for New Hampshire special education directors. The model assumes that four critical factors of human development outlined by Piaget and Meisels can be…
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Development of nurses with specialties: the nurse administrators' perspective.
Onishi, Mami; Sasaki, Minako; Nagata, Ayako; Kanda, Katsuya
2008-10-01
This study clarified how Japanese nurse administrators consider the current status and future prospects of development and utilization of nurses with specialties. The demand for specialized nurses is not satisfied throughout the country. Nine nurse administrators participated in three focus-group discussions. Data were analyzed using qualitative content analysis technique. On development of specialized nurses, four categories were abstracted: offering opportunities for career development; establishing an environment of life-term continuous learning; providing well-balanced support for the needs of organizations and individual nurses; and support for career development as a specialist. To develop specialized nurses effectively it is important to focus more attention on qualitative aspects of nurses' professional experience in in-service education and to support appropriate personnel for strategic human resource development. Facilitating frequent contacts between specialized and general nurses should be highly valued as making an environment where nurses can face career goals daily leads to steady preservation of human resources. It is necessary for nurse administrators to keep human resources quantitatively and to clarify the developmental process after nurses obtain special roles to plan for continuous education.
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ERIC Educational Resources Information Center
Walker, Gabriela
2010-01-01
Ten to twelve percent of the world population is identified as having one or more types of disability. This ecodeme has been historically known to be discriminated, marginalized, and disempowered by the lack of access to resources and to education. This article discusses the importance of adding special capital to the global human capital in the…
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48 CFR 335.071 - Special determinations and findings affecting research and development contracting.
Code of Federal Regulations, 2010 CFR
2010-10-01
... findings affecting research and development contracting. 335.071 Section 335.071 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 335.071 Special determinations and findings affecting research and development contracting. OPDIV...
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Special Issue: Book Reviews. Resources for Career Management, Counseling, Training and Development.
ERIC Educational Resources Information Center
Horvath, Clara, Ed.; And Others
1995-01-01
This special issue includes reviews of 32 books on the following topics: management, human resources, and organizational development; career counseling, guidance, and assessment; job search; resumes; careers in specific fields; careers for special populations; career transitions; and finding balance. (SK)
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-15
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Human Capital Interventions Across... Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-12
... Institute of Child Health and Human Development Special Emphasis Panel; Learning Disabilities Innovation... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-28
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Special Emphasis Panel, Loan Repayment Program... Scientific Review, National Institute Of Child Health And Human Development, 6100 Executive Boulevard...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-09
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Population Educational Training... Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-28
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Alexander Disease; Mechanisms... Officer, Division of Scientific Review, National Institute of Child Health And Human Development, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-13
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Reproductive Scientist Development...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-03
... Institute of Child Health and Human Development Special Emphasis Panel, Cognitive Development. Date... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-10
... National Institute of Child Health & Human Development Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Topics in Development, Signaling... Review, OD, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-11
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Cognitive Development. Date: April... Institute of Child Health and Human Development, 6100 Executive Boulevard, Rockville, MD 20892-9304, (301...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-20
... Institute of Child Health and Human Development Special Emphasis Panel, Maternal Fetal Medicine Units... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... 64735
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-07
... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Initiation of Human Labor... Human Development, 6100 Executive Boulevard, Room 5B01, Bethesda, MD 20892-7510, (301) 435- 6902, peter...
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ERIC Educational Resources Information Center
University of Pittsburgh Office of Child Development, 2011
2011-01-01
This Special Report discusses how the Allegheny County Department of Human Services and Pittsburgh Public Schools took a major step toward closing a knowledge gap that prevents schools and human service agencies around the country from developing a deeper understanding of the children in their systems and collaborating on more effective, better…
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-04
... Institute of Child Health and Human Development Special Emphasis Panel, The Role of Human-Animal Interaction... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-24
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development, Special Emphasis Panel. The Role of Human-Animal...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-02
... Institute of Child Health and Human Development Special Emphasis Panel Autism and Related Disorders Date... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-08
... Institute of Child Health and Human Development Special Emphasis Panel; Autism Center of Excellence: Network... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 executive blvd., Room...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-02
... Institute of Child Health and Human Development Special Emphasis Panel, Autism Centers of Excellence... National Institute of Child Health & Human Development; Notice of Closed Meetings Pursuant to section 10(d..., OD, Eunice Kennedy Shriver National Institute of Child Health And Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-17
...: National Institute of Child Health and Human Development Special Emphasis Panel; Novel Technologies in... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Scientific Review, National Institute of Child Health and Human Development, 6100 Executive Boulevard, Room...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-07
... Institute of Child Health and Human Development Special Emphasis Panel, Diabetes Risk Across Women's... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Kennedy Shriver National Institute of Child Health and Human Development, 6100 Executive Boulevard, Room...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-15
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Congenital Diaphragmatic Hernia..., Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-01
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development, Special Emphasis Panel. Alpha-Endosulfine in Mamalian..., Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-05
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development, Special Emphasis Panel, Neuroplasticity and the Maternal... Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-03
... Institute of Child Health and Human Development, Special Emphasis Panel, Maternal Fetal Medicine Units... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-24
... Institute of Child Health and Human Development Special Emphasis Group; Rehabilitation Medicine Scientist... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-01
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Committee: National Institute of Child Health and Human Development Special Emphasis Panel, Hypoxia in... Human Development, NIH, 6100 Executive Blvd., Room 5b01, Bethesda, MD 20892, (301) 435-6902, peter...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-08
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel Medical Rehabilitation Research... Institute, of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, 301-435...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-02
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Nature and Acquisition of Speech... Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-15
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Committee: National Institute of Child Health and Human Development Special Emphasis Panel; Rett Syndrome... Scientific Review, Eunice Kennedy Shriver National Institute of Child Health And Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-11
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Children's Research, Institute For... Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-28
... National Institute of Child Health & Human Development; Notice of Meeting Pursuant to section 10(d) of the... Committee: National Institute of Child Health and Human Development Special Emphasis Panel, Diet, Obesity... Health and Human Development, 6100 Executive Boulevard, Rockville, MD 20892-9304, (301) 435-6680...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-09
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special, Emphasis Panel, Global Health. Date: October 29... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-11
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Child Health Research Career..., Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-01
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Special Emphasis Panel; Safety and efficacy of... Kennedy Shriver National Institute of Child Health and Human Development, NIH 6100 Executive Blvd., Room...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-11
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Special Emphasis Group, Asymmetric Robotic Gait... Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-09
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Special Emphasis Panel; Maternofetal Signaling and... Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-23
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Committee: National Institute of Child Health and Human Development Special Emphasis Panel; Training... and Human Development, NIH, 6100 Executive Blvd., Room 5B01, Bethesda, MD 20892, 301-451- 3415...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-06
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Academic-Community Partnership... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-21
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development, Special Emphasis Panel, Topics In Female Reproduction. Date... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-02
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... of Committee: National Institute of Child Health and Human Development Special Emphasis Panel, ZHD1... of Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-01
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Molecular and Cellular Controls of... Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-12-07
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel. NICHD T32 Teleconference Review... of Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-04-02
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Population Research Infrastructure... Institute of Child Health and Human Development, NIH, 6100 Executive Boulevard, Room 5B01, Bethesda, MD...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-05-10
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel Congenital Defects Topics. Date: May..., Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-06
... National Institute of Child Health & Human Development Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Mentored Training in Executive... Review, National Institute of Child Health and Human Development, 6100 Executive Boulevard, Rockville, MD...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-07
... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Child Health Research Career... of Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and Human Development...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-01
... Institute of Child Health and Human Development Special Emphasis Panel; Theory of Mind Intervention. Date... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Kennedy Shriver National Institute, of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-09
... Institute of Child Health and Human Development; Special Emphasis Panel; Infertility Treatment, Child Growth... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-01
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Environmental and Biological...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-22
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, ``RECOVERY'' The National Standard...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-03
... Committee: National Institute of Child Health and Human Development Special Emphasis Panel, Spinal Circuits... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-23
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Donald Compton: Connections Among...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-19
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development; Special Emphasis Panel. Folic Acid Supplementation and...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-12
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Folic Acid/Zinc Sulfate...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-12
... Institute of Child Health and Human Development Special Emphasis Panel; Optimizing Social Communication in... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development Notice of Closed Meeting Pursuant to section 10(d...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-15
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; First and Second Trimester...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-01
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Special Emphasis Panel; Neonatal Research Network...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-28
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Social-Cognitive Skill Intervention...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-14
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Risk Genes and Environment...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-21
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development; Special Emphasis Panel; Ob/Gyn Postdoctoral Training...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-11-20
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Committee: National Institute of Child Health and Human Development Special Emphasis Panel; Contraceptive...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-06
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Genomic Sequencing and Newborn...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-05
... Institute of Child Health and Human Development Special Emphasis Panel, ZHD1 DRG-D 42 1. Date: July 10, 2013... Panel, ZHD1 DRG-D 41 1. Date: July 16, 2013. Time: 2:00 p.m. to 5:00 p.m. Agenda: To review and evaluate... Development Special Emphasis Panel, ZHD1 DRG-D 43 1. Date: August 1, 2013. Time: 2:00 p.m. to 5:00 p.m. Agenda...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-29
... Institute of Child Health and Human Development Special Emphasis Panel; The Ontogeny of Infant Detection of... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room 5B01...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-24
... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Special Emphasis Panel; Geisha. Date: July 13... Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room 5B01, Bethesda, MD 20892...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-05
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development, Special Emphasis Panel, Training Programs Health Sciences... of Child Health and Human Development, NIH, 6100 Executive Blvd., Room 5B01, Rockville, MD 20852, 301...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-14
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, ``VULVODYNIA''. Date: March 14, 2011... Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room 5B01, Bethesda, MD 20892...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-17
... Institute of Child Health and Human Development Special Emphasis Panel; Adolescent Medicine Trials Network... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d..., National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd. Room 5b01, Bethesda, MD...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-15
... Institute of Child Health and Human Development Special Emphasis Panel Parent-Child Processes. Date: August... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room 5B01, Bethesda, MD 20892...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-15
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Corpus Luteal Contribution to... Institute of Child Health and Human Development, NIH, 6100 Executive Boulevard, Rm. 5B01, Bethesda, MD 20892...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-07
... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel: Regulation of Placental Signaling... Health and Human Development, NIH, 6100 Executive Boulevard, Room 5B01, Bethesda, MD 20892-7510, (301...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-23
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; ZHD1 DSR-Z. Date: November 13, 2012... Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room 5B01...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-21
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development, Special Emphasis Panel, Resource Program Grant in... Child Health And Human Development, NIH, 6100 Executive Blvd., Room 5B01-G, Bethesda, MD 20892. 301-435...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-12
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; IEARDA. Date: June 6-7, 2011. Time... Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room 5B01, Bethesda, MD 20892...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-21
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; PMTCT. Date: July 17-18, 2012. Time... Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room 5b01, Bethesda, MD 20892...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-23
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Special Emphasis Panel; Global Data Center for... Human Development, NIH, 6100 Executive Blvd., Room 5B01, Bethesda, MD 20892-9304, 301-435-6680, skandasa...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-14
... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; CBPR and Health Disparities. Date... Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development, 6100...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-28
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, ZHD1 DRG (RL). Date: April 12, 2013..., Eunice Kennedy Shriver National Institute of Child Health And Human Development, NIH, 6100 Executive Blvd...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-21
... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Demographic/Behavioral Population... National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room 5B01, Bethesda...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-06
... National Institute of Child Health & Human Development Notice of Meeting Pursuant to section 10(a) of the... Committee: National Institute of Child Health and Human Development Special Emphasis Panel; ZHD1 DSR-K 58... Scientific Review, National Institute of Child Health and Human Development, 6100 Executive Boulevard, [[Page...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-11
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Maintenance of Child Health and... and Human Development, NIH, 6100 Executive Blvd., Room 5B01, Bethesda, MD 20892, 301-435-6680...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-02-01
... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Perinatal HIV-Infected Youth. Date... Health and Human Development, NIH, 6100 Executive Blvd., Room 5B01 Bethesda, MD 20892, (301) 496-1487...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-11
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Learning Disability Research Center... Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room 5B01, Bethesda, MD 20892...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-23
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; ZHD1 DSR-Y 41 1. Date: November 15... Kennedy Shriver National Institute of Child Health And Human Development, NIH, 6100 Executive Blvd., Room...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-03-28
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; ZHD1 DSR-H MR 1. Date: April 23... Kennedy Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-21
... National Institute of Child Health & Human Development; Notice of Closed Meetings Pursuant to section 10(d... Institute of Child Health and Human Development, Special Emphasis Panel, Reproductive Science Centers. Date... Institute of Child Health And Human Development, NIH, 6100 Executive Blvd., Room 5B01, Rockville, MD 20852...
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"Visual" Cortex of Congenitally Blind Adults Responds to Syntactic Movement.
Lane, Connor; Kanjlia, Shipra; Omaki, Akira; Bedny, Marina
2015-09-16
Human cortex is comprised of specialized networks that support functions, such as visual motion perception and language processing. How do genes and experience contribute to this specialization? Studies of plasticity offer unique insights into this question. In congenitally blind individuals, "visual" cortex responds to auditory and tactile stimuli. Remarkably, recent evidence suggests that occipital areas participate in language processing. We asked whether in blindness, occipital cortices: (1) develop domain-specific responses to language and (2) respond to a highly specialized aspect of language-syntactic movement. Nineteen congenitally blind and 18 sighted participants took part in two fMRI experiments. We report that in congenitally blind individuals, but not in sighted controls, "visual" cortex is more active during sentence comprehension than during a sequence memory task with nonwords, or a symbolic math task. This suggests that areas of occipital cortex become selective for language, relative to other similar higher-cognitive tasks. Crucially, we find that these occipital areas respond more to sentences with syntactic movement but do not respond to the difficulty of math equations. We conclude that regions within the visual cortex of blind adults are involved in syntactic processing. Our findings suggest that the cognitive function of human cortical areas is largely determined by input during development. Human cortex is made up of specialized regions that perform different functions, such as visual motion perception and language processing. How do genes and experience contribute to this specialization? Studies of plasticity show that cortical areas can change function from one sensory modality to another. Here we demonstrate that input during development can alter cortical function even more dramatically. In blindness a subset of "visual" areas becomes specialized for language processing. Crucially, we find that the same "visual" areas respond to a highly specialized and uniquely human aspect of language-syntactic movement. These data suggest that human cortex has broad functional capacity during development, and input plays a major role in determining functional specialization. Copyright © 2015 the authors 0270-6474/15/3512859-10$15.00/0.
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Career Development/Special Needs.
ERIC Educational Resources Information Center
1996
This document contains four papers presented at a symposium on career development and special needs moderated by James M. Brown at the 1996 conference of the Academy of Human Resource Development (AHRD). "Differential Rates of Employer Sponsored Job Training by Demographic Characteristics among Executives, Administrators, and Managers"…
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-25
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel--Assays of Biological Specimens in...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-09
... Institute of Child Health and Human Development Special Emphasis Panel, HIV Reproduction. Date: December 1... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meetings Pursuant to section 10(d...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-01
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Neuroscience Blueprint: Tools for...
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2010-11-08
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Prospective Analysis of...
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2010-10-12
... Institute of Child Health and Human Development Special Emphasis Panel; Natural History. Date: November 2... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...
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2010-02-19
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Institute of Child Health and Human Development Special...
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2010-06-24
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel National Childrens Study. Date: July..., Scientific Review Administrator, Division of Scientific Review, National Institute of Child Health and Human...
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2010-05-12
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Asymmetric Robotic Gait Training and... Review Administrator, Division of Scientific Review, National Institute of Child Health and Human...
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2010-05-12
... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Asymmetric Robotic Gait Training and... Review Administrator, Division of Scientific Review, National Institute of Child Health and Human...
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2010-06-04
... Institute of Child Health and Human Development Special Emphasis Panel; Race-Based Social Stress and Health... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-07-09
...: National Institute of Child Health and Human Development Special Emphasis Panel, Brain and Behavior. Date... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...
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2012-04-02
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; ZHD1 RRG-K 52 1, Rehabilitation...
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2013-09-12
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health and Human Development; Notice of Meeting Pursuant to section 10(d) of... Committee: National Institute of Child Health and Human Development Special Emphasis Panel; Further...
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2010-07-07
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Risk Genes and Environmental...
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2011-10-05
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, PAR-10-194, PAR10-203, PAR-11- 183... Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room 5B01-G, Bethesda, MD 20892...
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2012-06-21
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; ZHD1 DSR-Z 41 2. Date: July 19, 2012... Shriver National Institute of Child Health and Human Development, NIH, 6100 Executive Boulevard, Room 5B01...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-07
... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Genetic Causes And The Role Of The... Institute of Child Health and Human Development, 6100 Executive Boulevard, Room 5B01G, Bethesda, MD 20892...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-09-03
... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Special Emphasis Panel; Review of T32 Applications... Health and Human Development, NIH, 6100 Executive Blvd., Room 5B01, Bethesda, MD 20892, 301-435-6680...
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2012-03-20
... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; ZHD1 DSR-L 55 2. Date: April 10... Institute of Child Health and Human Development, NIH, 6100 Executive Blvd., Room 5B01, Bethesda, MD 20892...
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2012-06-06
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; ZHD1 DSR-W 90. Date: June 26, 2012... Shriver National Institute of Child Health And Human Development, NIH, 6100 Executive Boulevard, Room 5B01...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-09
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel. Date: October 30, 2012. Time: 3:00 p... Institute Of Child Health And Human Development, NIH, 6100 Executive Blvd., Room 5B01, Bethesda, MD 20892...
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Derivation of Multipotent Mesenchymal Precursors from Human Embryonic Stem Cells
Barberi, Tiziano; Willis, Lucy M; Socci, Nicholas D; Studer, Lorenz
2005-01-01
Background Human embryonic stem cells provide access to the earliest stages of human development and may serve as a source of specialized cells for regenerative medicine. Thus, it becomes crucial to develop protocols for the directed differentiation of embryonic stem cells into tissue-restricted precursors. Methods and Findings Here, we present culture conditions for the derivation of unlimited numbers of pure mesenchymal precursors from human embryonic stem cells and demonstrate multilineage differentiation into fat, cartilage, bone, and skeletal muscle cells. Conclusion Our findings will help to elucidate the mechanism of mesoderm specification during embryonic stem cell differentiation and provide a platform to efficiently generate specialized human mesenchymal cell types for future clinical applications. PMID:15971941
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-20
... Institute of Child Health and Human Development Special Emphasis Panel, The Development of Infant Behavioral... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Officer, Division of Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-07-29
... Institute of Child Health and Human Development, Special Emphasis Panel, ZHD1 DSR-H 51. Date: August 3, 2011... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d...
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2013-03-21
... Institute of Child Health and Human Development Special Emphasis Panel; ZHD1 DSR-H (NJ) Date: April 8, 2013... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...
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2011-10-17
... Institute of Child Health and Human Development, Special Emphasis Panel. ZHD1 DRG-H 40 1. Date: November 3... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...
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2012-04-26
... Institute of Child Health and Human Development Special Emphasis Panel; ZHD1 DSR-H 54 1. Date: May 7, 2012... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...
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2011-11-28
... Institute of Child Health and Human Development Special Emphasis Panel, ZHD1 DSR-H 40 1. Date: December 7... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...
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2012-07-24
... National Institute of Child Health and Human Development; Notice of Closed Meeting Pursuant to section 10(d... Health and Human Development Special Emphasis Panel; ZHD1 DSR-Z 42 2. Date: August 8, 2012. Time: 1:30 p... Institute of Child Health and Human Development, NIH, 6100 Executive Boulevard, Room 5B01, Bethesda, MD...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-21
... Institute of Child Health and Human Development Special Emphasis Group, Research on Children in Military Families: The Impact of Parental Military Deployment and Reintegration on Child and Family Functioning... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-14
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, National Children's Study-- Vanguard... Officer, Division of Scientific Review, Eunice Kennedy Shriver National Institute of Child Health and...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-24
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel Slack and Slick Channels. Date: July..., PhD, Scientific Review Administrator, Division of Scientific Review, National Institute of Child...
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2011-03-04
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Corpus Luteal Contribution to...., Scientific Review Officer, Division of Scientific Review, Eunice Kennedy Shriver National Institute of Child...
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2010-05-12
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel; Experimental Research on the Effects..., PhD, Scientific Review Administrator, Division of Scientific Review, National Institute of Child...
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General Assembly Governance H Human Development Human Rights I Indigenous Peoples Integral Development Scholarships School of Governance Science and Technology Social Development Summits of the Americas Sustainable - 2005 Quito, Ecuador - 2004 Santiago, Chile - 2003 Bridgetown, Barbados - 2002 Special Sessions Fifty
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Neandertals made the first specialized bone tools in Europe
Soressi, Marie; McPherron, Shannon P.; Lenoir, Michel; Dogandžić, Tamara; Goldberg, Paul; Jacobs, Zenobia; Maigrot, Yolaine; Martisius, Naomi L.; Miller, Christopher E.; Rendu, William; Richards, Michael; Skinner, Matthew M.; Steele, Teresa E.; Talamo, Sahra; Texier, Jean-Pierre
2013-01-01
Modern humans replaced Neandertals ∼40,000 y ago. Close to the time of replacement, Neandertals show behaviors similar to those of the modern humans arriving into Europe, including the use of specialized bone tools, body ornaments, and small blades. It is highly debated whether these modern behaviors developed before or as a result of contact with modern humans. Here we report the identification of a type of specialized bone tool, lissoir, previously only associated with modern humans. The microwear preserved on one of these lissoir is consistent with the use of lissoir in modern times to obtain supple, lustrous, and more impermeable hides. These tools are from a Neandertal context proceeding the replacement period and are the oldest specialized bone tools in Europe. As such, they are either a demonstration of independent invention by Neandertals or an indication that modern humans started influencing European Neandertals much earlier than previously believed. Because these finds clearly predate the oldest known age for the use of similar objects in Europe by anatomically modern humans, they could also be evidence for cultural diffusion from Neandertals to modern humans. PMID:23940333
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-25
... Health and Human Development Special Emphasis Panel; T32 Institutional Training Grant Award. Date... Rehabilitation Research; 93.209, Contraception and Infertility Loan Repayment Program, National Institutes of...
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ERIC Educational Resources Information Center
Groff, Warren H.
This package includes a description of Nova University's Human Resource Development (HRD) core seminar and seven doctoral student papers. The description (by Warren Groff) explains how a major curriculum change was made to convert the vocational, technical, and occupational specialization seminar, Personnel-Human Resources Development, to the core…
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-19
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d...: National Institute of Child Health and Human Development Special Emphasis Panel; Changing Parental Relationships and Child Well-Being. Date: March 5, 2010. Time: 1 p.m. to 4 p.m. Agenda: To review and evaluate...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-09
... National Institute of Child Health & Human Development; Notice of Closed Meeting Pursuant to section 10(d... Institute of Child Health and Human Development Special Emphasis Panel, Systematic Review of Neonatal Medicine. Date: May 23, 2011. Time: 1 p.m. to 3 p.m. Agenda: To review and evaluate grant applications...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-09-24
... Institute of Child Health and Human Development Special Emphasis Panel; Male Germline. Date: October 17..., Center for Medical Rehabilitation Research; 93.209, Contraception and Infertility Loan Repayment Program...
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-01
... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease... announced below concerns Development of an Evidenced-- Informed Mall Walking Program Resource Guide, Special... review, discussion, and evaluation of ``Development of an Evidenced--Informed Mall Walking Program...
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Developing Entrepreneurial Resilience: Implications for Human Resource Development
ERIC Educational Resources Information Center
Lee, Jin; Wang, Jia
2017-01-01
Purpose: Leadership development has attracted much research attention within the human resource development (HRD) community. However, little scholarly effort has been made to study a special group of leaders--entrepreneurs. This paper aims to fill in this knowledge gap by taking a close look at entrepreneurial resilience, a key ability of…
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Mahboobi-Ardakan, Payman; Kazemian, Mahmood; Mehraban, Sattar
2017-01-01
During different planning periods, human resources factor has been considerably increased in the health-care sector. The main goal is to determine economic planning conditions and equilibrium growth for services level and specialized workforce resources in health-care sector and also to determine the gap between levels of health-care services and specialized workforce resources in the equilibrium growth conditions and their available levels during the periods of the first to fourth development plansin Iran. In the study after data collection, econometric methods and EViews version 8.0 were used for data processing. The used model was based on neoclassical economic growth model. The results indicated that during the former planning periods, although specialized workforce has been increased significantly in health-care sector, lack of attention to equilibrium growth conditions caused imbalance conditions for product level and specialized workforce in health-care sector. In the past development plans for health services, equilibrium conditions based on the full employment in the capital stock, and specialized labor are not considered. The government could act by choosing policies determined by the growth model to achieve equilibrium level in the field of human resources and services during the next planning periods.
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-06-07
... Institute of Child Health and Human Development Special Emphasis Panel, Asthma Control During Pregnancy: Predictors of Variability in Maternal Impairment Due to Asthma and Associated Maternal and Pregnancy Outcomes...
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... pelvic exam, or special tests. Treatments include special pelvic muscle exercises called Kegel exercises. A mechanical support device called a pessary helps some women. Surgery and medicines are other treatments. NIH: National Institute of Child Health and Human Development
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ERIC Educational Resources Information Center
Perez-Foguet, A.; Oliete-Josa, S.; Saz-Carranza, A.
2005-01-01
Purpose: To show the key points of a development education program for engineering studies fitted within the framework of the human development paradigm. Design/methodology/approach: The bases of the concept of technology for human development are presented, and the relationship with development education analysed. Special attention is dedicated…
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-05-11
... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Developing Novel Diagnostic Tests To Improve Surveillance for Antimicrobial Resistant Pathogens, Funding Opportunity Announcement CI10-002; Initial Review Correction: This notice was...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-08-29
... Institute of Child Health and Human Development Special Emphasis Panel; Contraceptive Clinical Trials Network (Male Studies) September. Date: September 27, 2012. Time: 2 p.m. to 4 p.m. Agenda: To review and...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-29
... Institute of Child Health and Human Development Special Emphasis Panel ``STEM CELLS''. Date: July 20, 2010... Nos. 93.864, Population Research; 93.865, Research for Mothers and Children; 93.929, Center for...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-09
... Institute of Child Health and Human Development Special Emphasis Panel; Gene Therapy for Urea Disorders... prior to the meeting due to the timing limitations imposed by the review and funding cycle. (Catalogue...
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-17
... Institute of Child Health and Human Development Special Emphasis Panel; Data Archive on Adolescent Pregnancy and Pregnancy Prevention. Date: July 7, 2010. Time: 2 p.m. to 4 p.m. Agenda: To review and evaluate...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-26
... Institute of Child Health and Human Development Special Emphasis Panel, Pathophysiology of Intellectual and Developmental Disabilities. Date: June 17, 2011. Time: 2 p.m. to 5 p.m. Agenda: To review and evaluate grant...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-06-09
... Institute of Child Health and Human Development Special Emphasis Panel, Intellectual and Developmental Disabilities Research Centers 2011 (P30) Review. Date: June 29-30, 2011. Time: 8 a.m. to 6 p.m. Agenda: To...
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Federal Register 2010, 2011, 2012, 2013, 2014
2012-03-08
... Institute of Child Health and Human Development Special Emphasis Panel; A Low Molecular Weight Thyroid- Stimulating Hormone Receptor Agonist for Thyroid Cancer (SBIR Contract) Date: March 28, 2012. Time: 3 p.m. to...
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Adolescence: A Period of Transition
ERIC Educational Resources Information Center
Landmark, Leena Jo; Geye, Trina
2014-01-01
Because of the important role secondary special educators have in the transition to adulthood of adolescents with disabilities, it behooves educators to have an understanding of human development. The lifespan perspective on human development is particularly relevant to transition planning. Individuals with a lifespan perspective believe…
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AACP Special Taskforce White Paper on Diversifying Our Investment in Human Capital.
White, Carla; Conway, Jeannine M; Davis, Paula K; Johnson-Fannin, Arcelia M; Jurkas, Jeffrey G; Murphy, Nanci L; Smith, W Thomas; Echeverri, Margarita; Youmans, Sharon L; Owings, Katie C; Adams, Jennifer L
2017-10-01
The 2015-2017 American Association of Colleges of Pharmacy (AACP) Special Taskforce on Diversifying our Investment in Human Capital was appointed for a two-year term, due to the rigors and complexities of its charges. This report serves as a white paper for academic pharmacy on diversifying our investment in human capital. The Taskforce developed and recommended a representation statement that was adapted and adopted by the AACP House of Delegates at the 2016 AACP Annual Meeting. In addition, the Taskforce developed a diversity statement for the Association that was adopted by the AACP Board of Directors in 2017. The Taskforce also provides recommendations to AACP and to academic pharmacy in this white paper.
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[Circadian rhythm disruption and human development].
Kohyama, Jun
2013-12-01
Ontogenetic developments of rest-activity, sleep-wakefulness, temperature and several hormone rhythms in humans were reviewed. The reported effects of environment on these alterations were also summarized. Then, disorders or conditions which often encounter during early stage of life and reveal circadian rhythm disruptions were described. These disorders or conditions included severe brain damage, visual disturbance, developmental disorders(autistic spectrum disorder and attention deficit/hyperactivity disorder), Rett syndrome, Angelman syndrome, Smith-Magenis syndrome, epilepsy, Yonaki, and inadequate sleep hygiene. Finally, it was emphasized that we should pay special attention on the development of youngsters who showed sleep disturbance during early stage of life with special reference to the later occurrence of developmental disorders.
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Mahboobi-Ardakan, Payman; Kazemian, Mahmood; Mehraban, Sattar
2017-01-01
CONTEXT: During different planning periods, human resources factor has been considerably increased in the health-care sector. AIMS: The main goal is to determine economic planning conditions and equilibrium growth for services level and specialized workforce resources in health-care sector and also to determine the gap between levels of health-care services and specialized workforce resources in the equilibrium growth conditions and their available levels during the periods of the first to fourth development plansin Iran. MATERIALS AND METHODS: In the study after data collection, econometric methods and EViews version 8.0 were used for data processing. The used model was based on neoclassical economic growth model. RESULTS: The results indicated that during the former planning periods, although specialized workforce has been increased significantly in health-care sector, lack of attention to equilibrium growth conditions caused imbalance conditions for product level and specialized workforce in health-care sector. CONCLUSIONS: In the past development plans for health services, equilibrium conditions based on the full employment in the capital stock, and specialized labor are not considered. The government could act by choosing policies determined by the growth model to achieve equilibrium level in the field of human resources and services during the next planning periods. PMID:28616419
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Preschool Predictors of the Need for Early Remedial and Special Education Services
ERIC Educational Resources Information Center
Mann, Emily A.; McCartney, Kathleen; Park, Jennifer M.
2007-01-01
We examined child, family, and early child care predictors of teacher reports of referral for or placement in special and remedial education for 999 youth. Using data from the National Institute of Child Health and Human Development Study of Early Child Care and Youth Development and nested multivariate modeling techniques, we found that…
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Threats to Inclusive Education in Lesotho: An Overview of Policy and Implementation Challenges
ERIC Educational Resources Information Center
Mosia, Paseka Andrew
2014-01-01
This study looks at how the education of Learners with Special Education Needs (LSEN) has developed in Lesotho as a result of international policies on human rights and education. In particular, it explores various challenges to inclusive education such as proper understanding of inclusive education, the development of a policy on special and…
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The Diffusion of Disability Rights Policy: A Focus on Special Education in South Korea
ERIC Educational Resources Information Center
Yoo, Joan P.; Palley, Elizabeth
2014-01-01
This article examines the development of South Korean special education policy and suggests that different strategies of policy diffusion influenced the design of the policy at different times. Historically, South Korea relied on external pressures and influences, particularly US law and UN guidelines, to develop much of its human rights law,…
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ERIC Educational Resources Information Center
Jacques, Catherine; Potemski, Amy
2014-01-01
This Special Issues Brief from the Center on Great Teachers and Leaders (GTL Center) offers insight into three human capital management policies that are critical for career and technical education (CTE) teachers: certification, performance evaluation, and professional development. CTE teachers are uniquely positioned to improve college and career…
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45 CFR 1308.11 - Eligibility criteria: Hearing impairment including deafness.
Code of Federal Regulations, 2010 CFR
2010-10-01
... hearing loss can include impaired listening skills, delayed language development, and articulation... OF HUMAN DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR... frequently, and receive speech, language or hearing services as indicated by the IEPs. As soon as special...
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Washington, Stuart D.; Tillinghast, John S.
2015-01-01
A prominent hypothesis of hemispheric specialization for human speech and music states that the left and right auditory cortices (ACs) are respectively specialized for precise calculation of two canonically-conjugate variables: time and frequency. This spectral-temporal asymmetry does not account for sex, brain-volume, or handedness, and is in opposition to closed-system hypotheses that restrict this asymmetry to humans. Mustached bats have smaller brains, but greater ethological pressures to develop such a spectral-temporal asymmetry, than humans. Using the Heisenberg-Gabor Limit (i.e., the mathematical basis of the spectral-temporal asymmetry) to frame mustached bat literature, we show that recent findings in bat AC (1) support the notion that hemispheric specialization for speech and music is based on hemispheric differences in temporal and spectral resolution, (2) discredit closed-system, handedness, and brain-volume theories, (3) underscore the importance of sex differences, and (4) provide new avenues for phonological research. PMID:25926767
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Washington, Stuart D; Tillinghast, John S
2015-01-01
A prominent hypothesis of hemispheric specialization for human speech and music states that the left and right auditory cortices (ACs) are respectively specialized for precise calculation of two canonically-conjugate variables: time and frequency. This spectral-temporal asymmetry does not account for sex, brain-volume, or handedness, and is in opposition to closed-system hypotheses that restrict this asymmetry to humans. Mustached bats have smaller brains, but greater ethological pressures to develop such a spectral-temporal asymmetry, than humans. Using the Heisenberg-Gabor Limit (i.e., the mathematical basis of the spectral-temporal asymmetry) to frame mustached bat literature, we show that recent findings in bat AC (1) support the notion that hemispheric specialization for speech and music is based on hemispheric differences in temporal and spectral resolution, (2) discredit closed-system, handedness, and brain-volume theories, (3) underscore the importance of sex differences, and (4) provide new avenues for phonological research.
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Incorporating Human Rights into the College Curriculum.
ERIC Educational Resources Information Center
Ledbetter, Pat
This paper recounts development of a community college humanities course titled Human Rights/Human Wrongs: The History, Philosophy, Law, Art, and Literature of the Human Rights Movement. The author argues that a special focus, interdisciplinary course provides a broader base for exploring and understanding most of the pressing issues of our time.…
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-02-27
... Institute of Child Health and Human Development Special Emphasis Panel; Global Partnership for Social Science AIDS Research (R24). Date: March 21-22, 2013. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and...
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Web Resources for Teaching about Human Rights
ERIC Educational Resources Information Center
Merryfield, Merry M.; Badang, Germain; Bragg, Christina; Kvasov, Aleksandr; Taylor, Nathan; Waliaula, Anne; Yamaguchi, Misato
2012-01-01
The study of human rights is inseparable from social studies. Beyond the basic political, economic, and social freedoms and rights spelled out in The Universal Declaration of Human Rights, hundreds of specialized topics have developed that demonstrate the complex nature of human rights in the twenty-first-century world--environmental exploitation…
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Mapping Functional Brain Development: Building a Social Brain through Interactive Specialization
ERIC Educational Resources Information Center
Johnson, Mark H.; Grossmann, Tobias; Kadosh, Kathrin Cohen
2009-01-01
The authors review a viewpoint on human functional brain development, interactive specialization (IS), and its application to the emerging network of cortical regions referred to as the "social brain." They advance the IS view in 2 new ways. First, they extend IS into a domain to which it has not previously been applied--the emergence of social…
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AACP Special Taskforce White Paper on Diversifying Our Investment in Human Capital
White, Carla; Conway, Jeannine M.; Davis, Paula K.; Johnson-Fannin, Arcelia M.; Jurkas, Jeffrey G.; Murphy, Nanci L.; Smith, W. Thomas; Echeverri, Margarita; Youmans, Sharon L.; Owings, Katie C.; Adams, Jennifer L.
2017-01-01
EXECUTIVE SUMMARY The 2015-2017 American Association of Colleges of Pharmacy (AACP) Special Taskforce on Diversifying our Investment in Human Capital was appointed for a two-year term, due to the rigors and complexities of its charges. This report serves as a white paper for academic pharmacy on diversifying our investment in human capital. The Taskforce developed and recommended a representation statement that was adapted and adopted by the AACP House of Delegates at the 2016 AACP Annual Meeting. In addition, the Taskforce developed a diversity statement for the Association that was adopted by the AACP Board of Directors in 2017. The Taskforce also provides recommendations to AACP and to academic pharmacy in this white paper. PMID:29200461
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Extramural Activities, Fiscal Year 1969.
ERIC Educational Resources Information Center
National Inst. of Child Health and Human Development (NIH), Bethesda, MD.
The Adult Development and Aging Branch of the National Institute of Child Health and Human Development supports research and training relevant to the biological and behavioral changes that occur in humans with increasing age from the adult years through maturity and old age. Supported are research projects, training projects, special and…
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Tendencies of International Career of Romanian Researchers: Brain Drain?
ERIC Educational Resources Information Center
Popescu, Dan; Patrasca, Mihaela; Chivu, Iulia
2006-01-01
Recent economic and technological developments have led to a growing international demand for highly skilled human resources. The increased competition for human capital has determined numerous OECD countries to take special measures for attracting and retaining human capital in such fields as: information technology, biotechnology,…
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The Dialectical Humanism of Erich Fromm.
ERIC Educational Resources Information Center
Das, Ajit K.
1993-01-01
Presents overview of Erich Fromm's theory of human development with special emphasis on the origin of basic human needs, reciprocal interaction between these needs, and sociocultural structures that mold social character. Describes different types of social character in terms of socioeconomic structures that produce them. Describes features of…
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Molecular networks and the evolution of human cognitive specializations.
Fontenot, Miles; Konopka, Genevieve
2014-12-01
Inroads into elucidating the origins of human cognitive specializations have taken many forms, including genetic, genomic, anatomical, and behavioral assays that typically compare humans to non-human primates. While the integration of all of these approaches is essential for ultimately understanding human cognition, here, we review the usefulness of coexpression network analysis for specifically addressing this question. An increasing number of studies have incorporated coexpression networks into brain expression studies comparing species, disease versus control tissue, brain regions, or developmental time periods. A clearer picture has emerged of the key genes driving brain evolution, as well as the developmental and regional contributions of gene expression patterns important for normal brain development and those misregulated in cognitive diseases. Copyright © 2014 Elsevier Ltd. All rights reserved.
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Defending Rights in (Special) Education
ERIC Educational Resources Information Center
Ben-Porath, Sigal
2012-01-01
The state's commitment to educating all children can be framed as a matter of human capital development, or the economic benefits accrued to individuals and society as a result of educational attainment; it can be framed as a matter of capabilities, or the development of functionings that enable human flourishing; and it can be framed as a matter…
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Human Resource Development in Mauritius: Context, Challenges and Opportunities
ERIC Educational Resources Information Center
Garavan, Thomas N.; Neeliah, Harris; Auckloo, Raj; Ragaven, Raj
2016-01-01
Purpose: The purpose of this paper is to explore human resource development (HRD) in Mauritius and the challenges and opportunities faced by organisations in different sectors in adopting HRD practices. Findings: This special issue presents four papers that explore dimensions of HRD in public sector, small- and medium-sized enterprises (SMEs) and…
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Dust Storms: Why Are Dust Storms a Concern?
... matter , which can be a serious threat to human health if it accumulates in the respiratory system. Dust ... FIND-NLM National Institutes of Health Department of Health & Human Services Developed by Specialized Information Services, Environmental Health ...
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The Effective Use of Human Resources.
ERIC Educational Resources Information Center
Lippitt, Ronald
1980-01-01
In tandem with the energy crisis the author sees widespread misuse and waste of human resources. Analyzing issues of environmental deprivation, neglect of the old and the young, social isolation, the search for self, and specialization, he discusses ways that organizational and human resources development can address these challenges. (SK)
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49 CFR Appendix A to Part 604 - Listing of Human Service Federal Financial Assistance Programs
Code of Federal Regulations, 2010 CFR
2010-10-01
... Grant Administration for Children and Families Department of Health and Human Services. 10 Child Care and Development Fund Administration for Children and Families Department of Health and Human Services... of Education. 3 Assistance for Education of All Children with Disabilities—IDEA Office of Special...
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USASOC Injury Prevention/Performance Optimization Musculoskeletal Screening Initiative
2011-11-01
Tactical Human Optimization , Rapid Rehabilitation , and Reconditioning (THOR3) program to identify the...Special Operations Command (USASOC) to support development of USASOC’s Tactical Human Optimization , Rapid Rehabilitation , and Reconditioning (THOR3...biomechanical, musculoskeletal, physiological, tactical , and injury data and refine its current human performance program to address the
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-04-01
... DEPARTMENT OF HEALTH AND HUMAN SERVICES Administration for Children and Families Request for Public Comment on Proposed Funding Opportunity Announcement for Special Initiative Concerning the Assets... of the AFI program and Individual Development Accounts (IDAs). SUMMARY: In FY 2011, the Office of...
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ERIC Educational Resources Information Center
Weems, Carl F.; Overstreet, Stacy
2008-01-01
This article introduces the special section on child and adolescent mental health research in the context of Hurricane Katrina. We outline the purpose and intent of the special section and present an integrative perspective based on broad contextual theories of human development with which to think about the impact of disasters like Katrina. The…
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-05-20
... sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The contract proposals and the discussions... personal information concerning individuals associated with the contract proposals, the disclosure of which... Institute of Child Health and Human Development Special Emphasis Panel; Maintenance and Operation of a...
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The Importance of Comparative Psychology for Developmental Science
ERIC Educational Resources Information Center
Liebal, Katja; Haun, Daniel B. M.
2012-01-01
The aim of this essay is to elucidate the relevance of cross-species comparisons for the investigation of human behavior and its development. The focus is on the comparison of human children and another group of primates, the non-human great apes, with special attention to their cognitive skills. Integrating a comparative and developmental…
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Conceptual Development of Einstein's Mass-Energy Relationship
ERIC Educational Resources Information Center
Wong, Chee Leong; Yap, Kueh Chin
2005-01-01
Einstein's special theory of relativity was published in 1905. It stands as one of the greatest intellectual achievements in the history of human thought. Einstein described the equivalence of mass and energy as "the most important upshot of the special theory of relativity" (Einstein, 1919). In this paper, we will discuss the evolution of the…
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Crisis in the Philippines: A Threat to U.S. Interests.
ERIC Educational Resources Information Center
Gregor, A. James
The special relationship between the United States and the Philippines is chronicled, and the potential threats to that relationship are exposed and evaluated. Special attention is paid to imposition of martial law by Marcos from 1972-1981. The human rights of the Filipino people during martial law, development programs implemented by Marcos…
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Leveraging Human Assets: Interpersonal Skill Development Program
2006-11-01
workforce. Washington, DC: American Psychological Association. Vroom , V . (1964). Work and motivation . New York: John Wiley. ...considering the impact of motivation on interpersonal skills. Expectancy theory ( Vroom , 1964) includes expectancy and instrumentality. Expectancy is...important for success in special operations areas such as Civil Affairs (CA) or Special Forces (SF) that work closely with indigenous populations
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Foreword: Biomonitoring Equivalents special issue.
Meek, M E; Sonawane, B; Becker, R A
2008-08-01
The challenge of interpreting results of biomonitoring for environmental chemicals in humans is highlighted in this Foreword to the Biomonitoring Equivalents (BEs) special issue of Regulatory Toxicology and Pharmacology. There is a pressing need to develop risk-based tools in order to empower scientists and health professionals to interpret and communicate the significance of human biomonitoring data. The BE approach, which integrates dosimetry and risk assessment methods, represents an important advancement on the path toward achieving this objective. The articles in this issue, developed as a result of an expert panel meeting, present guidelines for derivation of BEs, guidelines for communication using BEs and several case studies illustrating application of the BE approach for specific substances.
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NASA Astrophysics Data System (ADS)
Xin, Sui; Lin, Lin; Chaoyang, Sun
2018-06-01
The quality of rural human settlement environment is directly related to the quality of urban human settlements, which is a big problem in the development of China's social economy. In the special period of social transformation and the key stage of building a well-off society comprehensively, it is of great practical significance to pay attention to the optimization of rural human settlement environment. China is in the transition from traditional rural landscape to modern rural landscape. However, how to realize the smooth transformation and the sustainable development of rural landscape is urgent and tough issues.
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-16
... Institute of Child Health and Human Development Special Emphasis Panel; Gene Therapy for Urea Cycle Disorders. Date: April 30, 2010. Time: 1:30 p.m. to 3 p.m. Agenda: To review and evaluate grant applications... prior to the meeting due to the timing limitations imposed by the review and funding cycle. (Catalogue...
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... help the symptoms. Treatments include physical, speech, and occupational therapy. Special education classes and psychological counseling can also help. NIH: National Institute of Child Health and Human Development
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Champion of Cultural Competence: An Interview with Donna Y. Ford
ERIC Educational Resources Information Center
Henshon, Suzanna E.
2008-01-01
This article presents an interview with Donna Y. Ford, a Professor of Education and Human Development at Vanderbilt University where she teaches in the Department of Special Education. Ford has been a Professor of Special Education at the Ohio State University, an Associate Professor of Educational Psychology at the University of Virginia, and a…
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Beyond Job Training: Rural Economic Development and the Two-Year College.
ERIC Educational Resources Information Center
Banks, Thomas A.
1990-01-01
Argues that rural two-year colleges must go beyond traditional job training programs for business/industry to have a decisive impact on local economic development. Presents a comprehensive economic development model, including human capital development; economic development awareness; and business, special group, infrastructure, and agricultural…
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The ortholog of the human proto-oncogene ROS1 is required for epithelial development in C. elegans
Jones, Martin R; Rose, Ann M; Baillie, David L
2013-01-01
The orphan receptor ROS1 is a human proto-oncogene, mutations of which are found in an increasing number of cancers. Little is known about the role of ROS1, however in vertebrates it has been implicated in promoting differentiation programs in specialized epithelial tissues. In this study we show that the C. elegans ortholog of ROS1, the receptor tyrosine kinase ROL-3, has an essential role in orchestrating the morphogenesis and development of specialized epidermal tissues, highlighting a potentially conserved function in coordinating crosstalk between developing epithelial cells. We also provide evidence of a direct relationship between ROL-3, the mucin SRAP-1, and BCC-1, the homolog of mRNA regulating protein Bicaudal-C. This study answers a longstanding question as to the developmental function of ROL-3, identifies three new genes that are expressed and function in the developing epithelium of C. elegans, and introduces the nematode as a potentially powerful model system for investigating the increasingly important, yet poorly understood, human oncogene ROS1. genesis 51:545–561. PMID:23733356
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Palliative Care and Human Rights: A Decade of Evolution in Standards.
Ezer, Tamar; Lohman, Diederik; de Luca, Gabriela B
2018-02-01
Human rights standards to address palliative care have developed over the last decade. This article aims to examine key milestones in the evolution of human rights standards to address palliative care, relevant advocacy efforts, and areas for further growth. The article provides an analysis of human rights standards in the context of palliative care through the lens of the right to health, freedom from torture and ill treatment, and the rights of older persons and children. Significant developments include the following: 1) the first human rights treaty to explicitly recognize the right to palliative care, the Inter-American Convention on the Rights of Older Persons; 2) the first World Health Assembly resolution on palliative care; 3) a report by the UN Special Rapporteur on Torture with a focus on denial of pain treatment; 4) addressing the availability of controlled medicines at the UN General Assembly Special Session on the World Drug Problem. Development of human rights standards in relation to palliative care has been most notable in the context of the right to health, freedom from torture and ill treatment, and the rights of older persons. More work is needed in the context of the rights of children, and human rights treaty bodies are still not consistently addressing state obligations with regards to palliative care. Copyright © 2017 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.
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ERIC Educational Resources Information Center
Russell, Jamie L.; Lyn, Heidi; Schaeffer, Jennifer A.; Hopkins, William D.
2011-01-01
The cultural intelligence hypothesis (CIH) claims that humans' advanced cognition is a direct result of human culture and that children are uniquely specialized to absorb and utilize this cultural experience (Tomasello, 2000). Comparative data demonstrating that 2.5-year-old human children outperform apes on measures of social cognition but not on…
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Solution to the Problems of the Sustainable Development Management
NASA Astrophysics Data System (ADS)
Rusko, Miroslav; Procházková, Dana
2011-01-01
The paper shows that environment is one of the basic public assets of a human system, and it must be therefore specially protected. According to our present knowledge, the sustainability is necessary for all human systems and it is necessary to invoke the sustainable development principles in all human system assets. Sustainable development is understood as a development that does not erode ecological, social or politic systems on which it depends, but it explicitly approves ecological limitation under the economic activity frame and it has full comprehension for support of human needs. The paper summarises the conditions for sustainable development, tools, methods and techniques to solve the environmental problems and the tasks of executive governance in the environmental segment.
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Hruby, Radovan; Maas, Lili M; Fedor-Freybergh, P G
2013-01-01
The article introduces an integrative psychoneurodevelopmental model of complex human brain and mind development based on the latest findings in prenatal and perinatal medicine in terms of integrative neuroscience. The human brain development is extraordinarily complex set of events and could be influenced by a lot of factors. It is supported by new insights into the early neuro-ontogenic processes with the help of structural 3D magnetic resonance imaging or diffusion tensor imaging of fetal human brain. Various factors and targets for neural development including birth weight variability, fetal and early-life programming, fetal neurobehavioral states and fetal behavioral responses to various stimuli and others are discussed. Molecular biology reveals increasing sets of genes families as well as transcription and neurotropic factors together with critical epigenetic mechanisms to be deeply employed in the crucial neurodevelopmental events. Another field of critical importance is psychoimmuno-neuroendocrinology. Various effects of glucocorticoids as well as other hormones, prenatal stress and fetal HPA axis modulation are thought to be of special importance for brain development. The early postnatal period is characterized by the next intense shaping of complex competences, induced mainly by the very unique mother - newborn´s interactions and bonding. All these mechanisms serve to shape individual human mind with complex abilities and neurobehavioral strategies. Continuous research elucidating these special competences of human fetus and newborn/child supports integrative neuroscientific approach to involve various scientific disciplines for the next progress in human brain and mind research, and opens new scientific challenges and philosophic attitudes. New findings and approaches in this field could establish new methods in science, in primary prevention and treatment strategies, and markedly contribute to the development of modern integrative and personalized medicine.
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Learning and adaptation: neural and behavioural mechanisms behind behaviour change
NASA Astrophysics Data System (ADS)
Lowe, Robert; Sandamirskaya, Yulia
2018-01-01
This special issue presents perspectives on learning and adaptation as they apply to a number of cognitive phenomena including pupil dilation in humans and attention in robots, natural language acquisition and production in embodied agents (robots), human-robot game play and social interaction, neural-dynamic modelling of active perception and neural-dynamic modelling of infant development in the Piagetian A-not-B task. The aim of the special issue, through its contributions, is to highlight some of the critical neural-dynamic and behavioural aspects of learning as it grounds adaptive responses in robotic- and neural-dynamic systems.
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Preuss, Todd M
2006-11-29
Understanding how humans differ from other animals, as well as how we are like them, requires comparative investigations. For the purpose of documenting the distinctive features of humans, the most informative research involves comparing humans to our closest relatives-the chimpanzees and other great apes. Psychology and anthropology have maintained a tradition of empirical comparative research on human specializations of cognition. The neurosciences, by contrast, have been dominated by the model-animal research paradigm, which presupposes the commonality of "basic" features of brain organization across species and discourages serious treatment of species differences. As a result, the neurosciences have made little progress in understanding human brain specializations. Recent developments in neuroimaging, genomics, and other non-invasive techniques make it possible to directly compare humans and nonhuman species at levels of organization that were previously inaccessible, offering the hope of gaining a better understanding of the species-specific features of the human brain. This hope will be dashed, however, if chimpanzees and other great ape species become unavailable for even non-invasive research.
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ERIC Educational Resources Information Center
Mehta, M.M.
Summaries of nine research projects completed and 26 research projects proposed or in progress, titles of papers produced in coordinated research and teaching programs, and a list of 13 international, national, or regional, seminars, conferences, or expert working group meetings contributing to human resources development in Asia and the Far East…
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-07-24
... sections 552b(c)(4) and 552b(c)(6), Title 5 U.S.C., as amended. The grant applications and the discussions... Health and Human Development Special Emphasis Panel; ZHD1 DSR-H GS 1. Date: August 15, 2013. Time: 3:15 p...) of the Federal Advisory Committee Act, as amended (5 U.S.C. App.), notice is hereby given of the...
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Bonini, Bárbara Barrionuevo; Freitas, Genival Fernandes de; Fairman, Julie; Mecone, Márcia Cristina da Cruz
2015-12-01
Objective To historicize the changes in training human resources in nursing in Brazil during the period from 1942 to 1961 based on the presence of 35 American nurses assigned to work in cooperation with Special Public Health Service. Method The sources used for the study were reports written by American nurses who described their impressions, suggestions, and the activities they carried out in the country. These were analyzed based on the discourse analysis of Michel Foucault. Results The period mentioned was marked by an American presence in nursing projects developed by the Special Public Health Service. The discourses indicated that the period was marked by many changes in Brazilian nursing, particularly with respect to attracting and training human resources for the profession. Conclusion The results indicate that the American nurses, through what they said and their influence, were central to the consolidation of a new paradigm in the training of nursing professionals in Brazil.
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Rewarding and Developing Staff in Higher Education: Invitation To Apply for Funds.
ERIC Educational Resources Information Center
Higher Education Funding Council for England, Bristol.
This document provides feedback on the Higher Education Funding Council for England (HEFCE) consultation (questionnaire responses about professional development in higher education) and invites higher education institutions to apply for special funding to support the development and implementation of human resource strategies. Responses to the…
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Unesco's General Information Programme for the 80s.
ERIC Educational Resources Information Center
United Nations Educational, Scientific and Cultural Organization, Paris (France). General Information Programme.
Developing countries are becoming increasingly aware of the fact that specialized information is essential to their economic and social development, and that it is an indispensable factor in the rational use of natural resources, the development of human resources, scientific and technological advancement, and progress in agriculture, industry,…
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Human influences on evolution, and the ecological and societal consequences
Hendry, Andrew P.; Svensson, Erik I.
2017-01-01
Humans have dramatic, diverse and far-reaching influences on the evolution of other organisms. Numerous examples of this human-induced contemporary evolution have been reported in a number of ‘contexts’, including hunting, harvesting, fishing, agriculture, medicine, climate change, pollution, eutrophication, urbanization, habitat fragmentation, biological invasions and emerging/disappearing diseases. Although numerous papers, journal special issues and books have addressed each of these contexts individually, the time has come to consider them together and thereby seek important similarities and differences. The goal of this special issue, and this introductory paper, is to promote and expand this nascent integration. We first develop predictions as to which human contexts might cause the strongest and most consistent directional selection, the greatest changes in evolutionary potential, the greatest genetic (as opposed to plastic) changes and the greatest effects on evolutionary diversification. We then develop predictions as to the contexts where human-induced evolutionary changes might have the strongest effects on the population dynamics of the focal evolving species, the structure of their communities, the functions of their ecosystems and the benefits and costs for human societies. These qualitative predictions are intended as a rallying point for broader and more detailed future discussions of how human influences shape evolution, and how that evolution then influences species traits, biodiversity, ecosystems and humans. This article is part of the themed issue ‘Human influences on evolution, and the ecological and societal consequences’. PMID:27920373
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Human Factors Tools for Improving Simulation Activities in Continuing Medical Education
ERIC Educational Resources Information Center
Seagull, F. Jacob
2012-01-01
Human factors (HF) is a discipline often drawn upon when there is a need to train people to perform complex, high-stakes tasks and effectively assess their performance. Complex tasks often present unique challenges for training and assessment. HF has developed specialized techniques that have been effective in overcoming several of these…
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Preface: Special issue on wildland fires
Alistair M. S. Smith; James A. Lutz; Chad M. Hoffman; Grant J. Williamson; Andrew T. Hudak
2018-01-01
Wildland fires are a critical Earth-system process that impacts human populations in each settled continent [1,2]. Wildland fires have often been stated as being essential to human life and civilization through the impacts on land clearance, agriculture, and hunting, with fire as a phenomenon serving a key role in the development of agricultural and industrial...
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Lateral specialization in unilateral spatial neglect: a cognitive robotics model.
Conti, Daniela; Di Nuovo, Santo; Cangelosi, Angelo; Di Nuovo, Alessandro
2016-08-01
In this paper, we present the experimental results of an embodied cognitive robotic approach for modelling the human cognitive deficit known as unilateral spatial neglect (USN). To this end, we introduce an artificial neural network architecture designed and trained to control the spatial attentional focus of the iCub robotic platform. Like the human brain, the architecture is divided into two hemispheres and it incorporates bio-inspired plasticity mechanisms, which allow the development of the phenomenon of the specialization of the right hemisphere for spatial attention. In this study, we validate the model by replicating a previous experiment with human patients affected by the USN and numerical results show that the robot mimics the behaviours previously exhibited by humans. We also simulated recovery after the damage to compare the performance of each of the two hemispheres as additional validation of the model. Finally, we highlight some possible advantages of modelling cognitive dysfunctions of the human brain by means of robotic platforms, which can supplement traditional approaches for studying spatial impairments in humans.
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Human-Robot Interaction: Status and Challenges.
Sheridan, Thomas B
2016-06-01
The current status of human-robot interaction (HRI) is reviewed, and key current research challenges for the human factors community are described. Robots have evolved from continuous human-controlled master-slave servomechanisms for handling nuclear waste to a broad range of robots incorporating artificial intelligence for many applications and under human supervisory control. This mini-review describes HRI developments in four application areas and what are the challenges for human factors research. In addition to a plethora of research papers, evidence of success is manifest in live demonstrations of robot capability under various forms of human control. HRI is a rapidly evolving field. Specialized robots under human teleoperation have proven successful in hazardous environments and medical application, as have specialized telerobots under human supervisory control for space and repetitive industrial tasks. Research in areas of self-driving cars, intimate collaboration with humans in manipulation tasks, human control of humanoid robots for hazardous environments, and social interaction with robots is at initial stages. The efficacy of humanoid general-purpose robots has yet to be proven. HRI is now applied in almost all robot tasks, including manufacturing, space, aviation, undersea, surgery, rehabilitation, agriculture, education, package fetch and delivery, policing, and military operations. © 2016, Human Factors and Ergonomics Society.
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Gunnar, Megan R.; Hostinar, Camelia E.; Sanchez, Mar M.; Tottenham, Nim; Sullivan, Regina M.
2016-01-01
It has been long recognized that parents exert profound influences on child development. Dating back to at least the seventeenth-century Enlightenment, the ability for parents to shape child behavior in an enduring way has been noted. Twentieth-century scholars developed theories to explain how parenting histories influence psychological development, and since that time, the number of scientific publications on parenting influences in both human and nonhuman animal fields has grown at an exponential rate, reaching numbers in the thousands by 2015. This special issue describes a symposium delivered by Megan Gunnar, Regina Sullivan, Mar Sanchez, and Nim Tottenham in the Fall of 2014 at the Society for Social Neuroscience. The goal of the symposium was to describe the emerging knowledge on neurobiological mechanisms that mediate parent–offspring interactions across three different species: rodent, monkey, and human. The talks were aimed at designing testable models of parenting effects on the development of emotional and stress regulation. Specifically, the symposium aimed at characterizing the special modulatory (buffering) effects of parental cues on fear- and stress-relevant neurobiology and behaviors of the offspring and to discuss examples of impaired buffering when the parent–infant relationship is disrupted. PMID:26234160
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Gunnar, Megan R; Hostinar, Camelia E; Sanchez, Mar M; Tottenham, Nim; Sullivan, Regina M
2015-01-01
It has been long recognized that parents exert profound influences on child development. Dating back to at least the seventeenth-century Enlightenment, the ability for parents to shape child behavior in an enduring way has been noted. Twentieth-century scholars developed theories to explain how parenting histories influence psychological development, and since that time, the number of scientific publications on parenting influences in both human and nonhuman animal fields has grown at an exponential rate, reaching numbers in the thousands by 2015. This special issue describes a symposium delivered by Megan Gunnar, Regina Sullivan, Mar Sanchez, and Nim Tottenham in the Fall of 2014 at the Society for Social Neuroscience. The goal of the symposium was to describe the emerging knowledge on neurobiological mechanisms that mediate parent-offspring interactions across three different species: rodent, monkey, and human. The talks were aimed at designing testable models of parenting effects on the development of emotional and stress regulation. Specifically, the symposium aimed at characterizing the special modulatory (buffering) effects of parental cues on fear- and stress-relevant neurobiology and behaviors of the offspring and to discuss examples of impaired buffering when the parent-infant relationship is disrupted.
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JUNIOR AND SENIOR HIGH SCHOOL GRADUATION REQUIREMENTS AND CURRICULA.
ERIC Educational Resources Information Center
GOLDBLUM, JANICE; AND OTHERS
GRADUATION REQUIREMENTS AND CURRICULUMS IN THE LOS ANGELES CITY SCHOOL SYSTEM INSURE INTELLECTUAL DEVELOPMENT, CIVIC RESPONSIBILITY, ECONOMIC COMPETENCY, CREATIVITY, DEVELOPMENT OF MORAL VALUES, GOOD HUMAN RELATIONS, AND HEALTH. GRADING, TRANSFERS, HOMEWORK, CREDIT, AND SPECIAL POLICIES ARE DISCUSSED. THE CURRICULUM IN JUNIOR AND SENIOR HIGH…
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5 CFR 9701.363 - Special staffing payments.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Special staffing payments. 9701.363 Section 9701.363 Administrative Personnel DEPARTMENT OF HOMELAND SECURITY HUMAN RESOURCES MANAGEMENT... HUMAN RESOURCES MANAGEMENT SYSTEM Pay and Pay Administration Special Payments § 9701.363 Special...
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5 CFR 9701.362 - Special assignment payments.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Special assignment payments. 9701.362 Section 9701.362 Administrative Personnel DEPARTMENT OF HOMELAND SECURITY HUMAN RESOURCES MANAGEMENT... HUMAN RESOURCES MANAGEMENT SYSTEM Pay and Pay Administration Special Payments § 9701.362 Special...
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Effects of Caffeine and Warrior Stress on Behavioral : An Animal Model
2016-03-14
contributes invaluably to ethical and humane research. A special thank you to Erin Barry for providing statistical expertise and methodological support...of behavioral health in rats. Several ethical and logistical issues prevent the use of humans in true controlled experiments that manipulate stress...play in the development or maintenance of behavioral problems. There are ethical issues associated with exposing humans to high caffeine doses and
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Transcriptional specialization of human dendritic cell subsets in response to microbial vaccines
Banchereau, Romain; Baldwin, Nicole; Cepika, Alma-Martina; Athale, Shruti; Xue, Yaming; Yu, Chun I; Metang, Patrick; Cheruku, Abhilasha; Berthier, Isabelle; Gayet, Ingrid; Wang, Yuanyuan; Ohouo, Marina; Snipes, LuAnn; Xu, Hui; Obermoser, Gerlinde; Blankenship, Derek; Oh, Sangkon; Ramilo, Octavio; Chaussabel, Damien; Banchereau, Jacques; Palucka, Karolina; Pascual, Virginia
2014-01-01
The mechanisms by which microbial vaccines interact with human APCs remain elusive. Herein, we describe the transcriptional programs induced in human DCs by pathogens, innate receptor ligands and vaccines. Exposure of DCs to influenza, Salmonella enterica and Staphylococcus aureus allows us to build a modular framework containing 204 transcript clusters. We use this framework to characterize the responses of human monocytes, monocyte-derived DCs and blood DC subsets to 13 vaccines. Different vaccines induce distinct transcriptional programs based on pathogen type, adjuvant formulation and APC targeted. Fluzone, Pneumovax and Gardasil, respectively, activate monocyte-derived DCs, monocytes and CD1c+ blood DCs, highlighting APC specialization in response to vaccines. Finally, the blood signatures from individuals vaccinated with Fluzone or infected with influenza reveal a signature of adaptive immunity activation following vaccination and symptomatic infections, but not asymptomatic infections. These data, offered with a web interface, may guide the development of improved vaccines. PMID:25335753
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ERIC Educational Resources Information Center
Maine State Dept. of Educational and Cultural Services, Augusta. Div. of Special Education.
In this cooperative agreement, Maine's Division of Special Education, Bureau of Adult and Secondary Vocational Education, and Bureau of Rehabilitation (including the Vocational Rehabilitation Program and the Division of Eye Care) document their intent to develop collaboratively programs to provide educational, vocational, occupational, supportive,…
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Education Trends, Norms and Development.
ERIC Educational Resources Information Center
Abdel-Magid, Isam Mohammed; Elsadig, Elsadig Hassan
The impact of globalization on vocational-technical education (VTE) and human resource development (HRD) in Sudan was examined. Special attention was paid to the following issues: the purpose of education in the 21st century; learning for the workplace; national culture and technological advances; the globalization of education; education and…
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40 CFR 435.41 - Specialized definitions.
Code of Federal Regulations, 2011 CFR
2011-07-01
... separation even if located separately from wellheads. (dd) Sanitary waste means the human body waste... means the water area and water body floor beneath any exploratory, development, or production facility... preparing an area of the water body floor for the purpose of constructing or placing a development or...
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Educating the Developing Mind: Towards an Overarching Paradigm
ERIC Educational Resources Information Center
Demetriou, Andreas; Spanoudis, George; Mouyi, Antigoni
2011-01-01
This essay first summarizes an overarching theory of cognitive organization and development. This theory claims that the human mind involves (1) several specialized structural systems dealing with different domains of relations in the environment, (2) a central representational capacity system, (3) general inferential processes, and (4)…
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Human influences on evolution, and the ecological and societal consequences.
Hendry, Andrew P; Gotanda, Kiyoko M; Svensson, Erik I
2017-01-19
Humans have dramatic, diverse and far-reaching influences on the evolution of other organisms. Numerous examples of this human-induced contemporary evolution have been reported in a number of 'contexts', including hunting, harvesting, fishing, agriculture, medicine, climate change, pollution, eutrophication, urbanization, habitat fragmentation, biological invasions and emerging/disappearing diseases. Although numerous papers, journal special issues and books have addressed each of these contexts individually, the time has come to consider them together and thereby seek important similarities and differences. The goal of this special issue, and this introductory paper, is to promote and expand this nascent integration. We first develop predictions as to which human contexts might cause the strongest and most consistent directional selection, the greatest changes in evolutionary potential, the greatest genetic (as opposed to plastic) changes and the greatest effects on evolutionary diversification We then develop predictions as to the contexts where human-induced evolutionary changes might have the strongest effects on the population dynamics of the focal evolving species, the structure of their communities, the functions of their ecosystems and the benefits and costs for human societies. These qualitative predictions are intended as a rallying point for broader and more detailed future discussions of how human influences shape evolution, and how that evolution then influences species traits, biodiversity, ecosystems and humans.This article is part of the themed issue 'Human influences on evolution, and the ecological and societal consequences'. © 2016 The Author(s).
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Understanding childbirth practices as an organizational cultural phenomenon: a conceptual framework.
Behruzi, Roxana; Hatem, Marie; Goulet, Lise; Fraser, William; Misago, Chizuru
2013-11-11
Understanding the main values and beliefs that might promote humanized birth practices in the specialized hospitals requires articulating the theoretical knowledge of the social and cultural characteristics of the childbirth field and the relations between these and the institution. This paper aims to provide a conceptual framework allowing examination of childbirth practices through the lens of an organizational culture theory. A literature review performed to extrapolate the social and cultural factors contribute to birth practices and the factors likely overlap and mutually reinforce one another, instead of complying with the organizational culture of the birth place. The proposed conceptual framework in this paper examined childbirth patterns as an organizational cultural phenomenon in a highly specialized hospital, in Montreal, Canada. Allaire and Firsirotu's organizational culture theory served as a guide in the development of the framework. We discussed the application of our conceptual model in understanding the influences of organizational culture components in the humanization of birth practices in the highly specialized hospitals and explained how these components configure both the birth practice and women's choice in highly specialized hospitals. The proposed framework can be used as a tool for understanding the barriers and facilitating factors encountered birth practices in specialized hospitals.
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The Development of Altruism with Special Reference to Human Relationships: A 10-Stage Theory.
Ma, Hing Keung
2017-01-01
All human relationships involve some form of cost and benefit and altruism forms the foundation upon which human relationships are built. In this paper, a taxonomy of human relationships in terms of altruism was constructed. In the proposed taxonomy, human relationships are categorized into three major groups: primary group, secondary group, and tertiary group. The primary group consists of members that are very closely related to each other either by genetic relatedness (e.g., parents, siblings, and cousins) or social relatedness (e.g., mate and close friends) or both. The secondary group consists of members that are socially related but also less closely related with each other (e.g., people of the same political or religious group, teachers, mentors, acquaintances, neighbors, working colleagues, and strangers). Lastly, the tertiary group consists of members of other species. A 10-stage theory of altruism with special reference to human relationships is proposed. The affective, cognitive, and relationship aspects of each stage are delineated in details. There are two developmental principles of altruism. The first principle states that the development of altruism follows the 10-stage theory and moves from Stage 1: Egoism toward the higher stages of altruism slowly. The second developmental principle states that the taxonomy of human relationships is valid at any stage of altruism development. In other words, people at any stage of altruism are more altruistic toward their kin and mate, and then close friends, extended family members, and so on. They are least altruistic toward enemies and members of non-human species. In summary, the proposed developmental principle of altruism and human relationships is logical and robust. It is formulated based on the major developmental and social psychological theories. The theory has the potential in providing a useful framework for future studies on the development and evolution of human relationships.
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The Development of Altruism with Special Reference to Human Relationships: A 10-Stage Theory
Ma, Hing Keung
2017-01-01
All human relationships involve some form of cost and benefit and altruism forms the foundation upon which human relationships are built. In this paper, a taxonomy of human relationships in terms of altruism was constructed. In the proposed taxonomy, human relationships are categorized into three major groups: primary group, secondary group, and tertiary group. The primary group consists of members that are very closely related to each other either by genetic relatedness (e.g., parents, siblings, and cousins) or social relatedness (e.g., mate and close friends) or both. The secondary group consists of members that are socially related but also less closely related with each other (e.g., people of the same political or religious group, teachers, mentors, acquaintances, neighbors, working colleagues, and strangers). Lastly, the tertiary group consists of members of other species. A 10-stage theory of altruism with special reference to human relationships is proposed. The affective, cognitive, and relationship aspects of each stage are delineated in details. There are two developmental principles of altruism. The first principle states that the development of altruism follows the 10-stage theory and moves from Stage 1: Egoism toward the higher stages of altruism slowly. The second developmental principle states that the taxonomy of human relationships is valid at any stage of altruism development. In other words, people at any stage of altruism are more altruistic toward their kin and mate, and then close friends, extended family members, and so on. They are least altruistic toward enemies and members of non-human species. In summary, the proposed developmental principle of altruism and human relationships is logical and robust. It is formulated based on the major developmental and social psychological theories. The theory has the potential in providing a useful framework for future studies on the development and evolution of human relationships. PMID:29085818
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Nutrition, Growth and Development of North American Indian Children. Monograph.
ERIC Educational Resources Information Center
Moore, William M., Ed.; And Others
Recognizing the special health needs of disadvantaged minority groups, in May 1969 the National Institute of Child Health and Human Development cosponsored a conference on these needs for North American Indian children. The monograph, based on this conference, summarizes previous knowledge, provides new information, and emphasizes the role of…
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Maschi, Tina; Viola, Deborah; Sun, Fei
2013-08-01
The aging prisoner crisis continues to gain international attention as the high human, social, and economic costs of warehousing older adults with complex physical, mental health, and social care needs in prison continues to rise. According to the United Nations, older adults and the serious and terminally ill are considered special needs populations subject to special international health and social practice and policy considerations. We argue that older adults in prison have unique individual and social developmental needs that result from life course exposure to cumulative risk factors compounded by prison conditions that accelerate their aging. We position these factors in a social context model of human development and well-being and present a review of international human rights guidelines that pertain to promoting health and well-being to those aging in custody. The study concludes with promising practices and recommendations of their potential to reduce the high direct and indirect economic costs associated with mass confinement of older adults, many of whom need specialized long-term care that global correctional systems are inadequately equipped to provide.
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The importance of touch in the development of attachment.
Duhn, Lenora
2010-12-01
Until recently the role of human touch in the social world of the developing infant has not been given special attention. Instead the focus, in part due to John Bowlby's Attachment Theory, has centered on the critical need for a child to develop a secure attachment to his caregiver. To be sure, this has provided a valuable contribution to understanding and promoting a child's well-being in his early years and beyond. Yet Bowlby's theory is limited in its discussion of the meaning of human touch and its role in development of attachment. As such, it now becomes more critical to delve into the factors that significantly foster development of attachment, specifically the concept of human touch. With recognition of the importance for a child to develop secure attachment to his caregiver, the essential function that human nurturing touch provides in facilitating that connection is explored.
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ERIC Educational Resources Information Center
St. John, Edward P.
As part of a study of selected developing colleges and universities funded in the Advanced Institutional Development Program (AIDP), this report focuses on St. Mary's Junior College (SMJC), a Roman Catholic, two-year college specializing exclusively in health, health-related and human service fields. The report considers SMJC's state of…
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Jaung, Michael; Jani, Suni; Banu, Sophia; Mackey, Joy M
2017-09-01
Mental health disorders are a major cause of morbidity and a growing burden in low-income and middle-income countries; but there is little existing literature on the detailed epidemiology, diagnosis, and treatment in low-resource settings. Special situations with vulnerable populations, such as those created by international humanitarian emergencies, refugees or internally displaced people, and victims of human trafficking, are increasing in prevalence. These victims are often resettled in developed countries and come to the emergency department seeking care. To better care for these populations, knowledge of specialized psychosocial and cultural considerations should inform the comprehensive psychiatric assessment and treatment plan. Copyright © 2017 Elsevier Inc. All rights reserved.
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Information Technology and the Human Research Facility
NASA Technical Reports Server (NTRS)
Klee, Margaret
2002-01-01
This slide presentation reviews how information technology supports the Human Research Facility (HRF) and specifically the uses that contractor has for the information. There is information about the contractor, the HRF, some of the experiments that were performed using the HRF on board the Shuttle, overviews of the data architecture, and software both commercial and specially developed software for the specific experiments.
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Neighborhood-Based Child Care Services for the Inner City. Manpower for the Human Services.
ERIC Educational Resources Information Center
Kassel, Myrna Bordelon
This monograph is the fifth in a series summarizing the work progress of the Human Services Manpower Career Center, a special research and development project funded by the U. S. Department of Labor. This report describes the action taken by a committee of child care workers, educators, welfare mothers, manpower specialists, and concerned lay…
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Natural Language as a Tool for Analyzing the Proving Process: The Case of Plane Geometry Proof
ERIC Educational Resources Information Center
Robotti, Elisabetta
2012-01-01
In the field of human cognition, language plays a special role that is connected directly to thinking and mental development (e.g., Vygotsky, "1938"). Thanks to "verbal thought", language allows humans to go beyond the limits of immediately perceived information, to form concepts and solve complex problems (Luria, "1975"). So, it appears language…
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Hernández Blasi, Carlos; Causey, Kayla
2010-02-01
This is an introduction to this special issue on evolutionary psychology (EP) and evolutionary developmental psychology (EDP). We suggest here that, contrary to some common assumptions, mainstream psychology continues to be essentially non Darwinian and that EP and EDP are new approaches that can potentially help us to change this situation. We then present the organization of the special issue (composed of six papers). We conclude that evolution is certainly not the final consideration in psychology, but emphasize its importance as the basis upon which all modern behaviors and development are built.
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NASA Technical Reports Server (NTRS)
1988-01-01
American Bar Codes, Inc. developed special bar code labels for inventory control of space shuttle parts and other space system components. ABC labels are made in a company-developed anodizing aluminum process and consecutively marketed with bar code symbology and human readable numbers. They offer extreme abrasion resistance and indefinite resistance to ultraviolet radiation, capable of withstanding 700 degree temperatures without deterioration and up to 1400 degrees with special designs. They offer high resistance to salt spray, cleaning fluids and mild acids. ABC is now producing these bar code labels commercially or industrial customers who also need labels to resist harsh environments.
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Stand-off detection of alcohol in car cabins
NASA Astrophysics Data System (ADS)
Młyńczak, Jarosław; Kubicki, Jan; Kopczyński, Krzysztof
2014-01-01
The results of experiments concerning detection of alcohol vapors in car cabins using a laboratory device, which was developed and built at the Institute of Optoelectronics at the Military University of Technology, are described. The work is a continuation of the investigations presented in an earlier paper. On the basis of those results, the whole device was designed and built. Then it was investigated using a car with special system simulating a driver under the influence of alcohol. To simulate the appropriate concentration of alcohol in human blood, a special method of generation of alcohol vapor was developed.
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Human history and deep time in nineteenth-century British sciences: An introduction.
Sera-Shriar, Efram
2015-06-01
The historicisation of humans was a major endeavour in nineteenth-century Britain, and one that led to wide-ranging debates involving a variety of disciplinary approaches, new and old. Within the context of science and medicine these discussions centred on the issues of human origins and evolution. Did the various races living throughout the world develop from a single location, or were their physical and social differences evidence for their separate genesis? Which disciplinary tradition offered the best method for tracing human development? Was it even possible to trace that development, or had too much time passed since the dawn of humans? Furthermore, who had the authority to speak about these matters? This special issue will examine these core questions and introduce some of the ways that researchers attempted to historicise humans within the context of nineteenth-century British sciences. Copyright © 2015 Elsevier Ltd. All rights reserved.
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Kim, Judy S; Kanjlia, Shipra; Merabet, Lotfi B; Bedny, Marina
2017-11-22
Learning to read causes the development of a letter- and word-selective region known as the visual word form area (VWFA) within the human ventral visual object stream. Why does a reading-selective region develop at this anatomical location? According to one hypothesis, the VWFA develops at the nexus of visual inputs from retinotopic cortices and linguistic input from the frontotemporal language network because reading involves extracting linguistic information from visual symbols. Surprisingly, the anatomical location of the VWFA is also active when blind individuals read Braille by touch, suggesting that vision is not required for the development of the VWFA. In this study, we tested the alternative prediction that VWFA development is in fact influenced by visual experience. We predicted that in the absence of vision, the "VWFA" is incorporated into the frontotemporal language network and participates in high-level language processing. Congenitally blind ( n = 10, 9 female, 1 male) and sighted control ( n = 15, 9 female, 6 male), male and female participants each took part in two functional magnetic resonance imaging experiments: (1) word reading (Braille for blind and print for sighted participants), and (2) listening to spoken sentences of different grammatical complexity (both groups). We find that in blind, but not sighted participants, the anatomical location of the VWFA responds both to written words and to the grammatical complexity of spoken sentences. This suggests that in blindness, this region takes on high-level linguistic functions, becoming less selective for reading. More generally, the current findings suggest that experience during development has a major effect on functional specialization in the human cortex. SIGNIFICANCE STATEMENT The visual word form area (VWFA) is a region in the human cortex that becomes specialized for the recognition of written letters and words. Why does this particular brain region become specialized for reading? We tested the hypothesis that the VWFA develops within the ventral visual stream because reading involves extracting linguistic information from visual symbols. Consistent with this hypothesis, we find that in congenitally blind Braille readers, but not sighted readers of print, the VWFA region is active during grammatical processing of spoken sentences. These results suggest that visual experience contributes to VWFA specialization, and that different neural implementations of reading are possible. Copyright © 2017 the authors 0270-6474/17/3711495-10$15.00/0.
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Kanjlia, Shipra; Merabet, Lotfi B.
2017-01-01
Learning to read causes the development of a letter- and word-selective region known as the visual word form area (VWFA) within the human ventral visual object stream. Why does a reading-selective region develop at this anatomical location? According to one hypothesis, the VWFA develops at the nexus of visual inputs from retinotopic cortices and linguistic input from the frontotemporal language network because reading involves extracting linguistic information from visual symbols. Surprisingly, the anatomical location of the VWFA is also active when blind individuals read Braille by touch, suggesting that vision is not required for the development of the VWFA. In this study, we tested the alternative prediction that VWFA development is in fact influenced by visual experience. We predicted that in the absence of vision, the “VWFA” is incorporated into the frontotemporal language network and participates in high-level language processing. Congenitally blind (n = 10, 9 female, 1 male) and sighted control (n = 15, 9 female, 6 male), male and female participants each took part in two functional magnetic resonance imaging experiments: (1) word reading (Braille for blind and print for sighted participants), and (2) listening to spoken sentences of different grammatical complexity (both groups). We find that in blind, but not sighted participants, the anatomical location of the VWFA responds both to written words and to the grammatical complexity of spoken sentences. This suggests that in blindness, this region takes on high-level linguistic functions, becoming less selective for reading. More generally, the current findings suggest that experience during development has a major effect on functional specialization in the human cortex. SIGNIFICANCE STATEMENT The visual word form area (VWFA) is a region in the human cortex that becomes specialized for the recognition of written letters and words. Why does this particular brain region become specialized for reading? We tested the hypothesis that the VWFA develops within the ventral visual stream because reading involves extracting linguistic information from visual symbols. Consistent with this hypothesis, we find that in congenitally blind Braille readers, but not sighted readers of print, the VWFA region is active during grammatical processing of spoken sentences. These results suggest that visual experience contributes to VWFA specialization, and that different neural implementations of reading are possible. PMID:29061700
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Perfetti, Charles; Cao, Fan; Booth, James
2014-01-01
Understanding Chinese reading is important for identifying the universal aspects of reading, separated from those aspects that are specific to alphabetic writing or to English in particular. Chinese and alphabetic writing make different demands on reading and learning to read, despite reading procedures and their supporting brain networks that are partly universal. Learning to read accommodates the demands of a writing system through the specialization of brain networks that support word identification. This specialization increases with reading development, leading to differences in the brain networks for alphabetic and Chinese reading. We suggest that beyond reading procedures that are partly universal and partly writing-system specific, functional reading universals arise across writing systems in their adaptation to human cognitive abilities. PMID:24744605
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Research on optimization of test cycles for comfort to the special vehicles
NASA Astrophysics Data System (ADS)
Mitroi, Marian; Chiru, Anghel
2017-10-01
The comfort of vehicles, regardless of their type is represent a requirement to by fulfilled in the context of current technological developments special vehicles generally move under different soil, time, or season conditions, and the land in which the vehicles move is complex and varied in the physical structure. Due to the high level of involvement in the driveability, safety and comfort of automotive, suspension system is a key factor with major implications for vibration and noise, affecting the human body. The objective of the research is related to determining the test cycles of special vehicles that are approaching real situations, to determine the level of comfort. The evaluate of the degree of comfort will be realized on acceleration values recorded, especially the vertical ones that have the highest influence on the human body. Thus, in this way the tests can be established needed to determine the level of comfort required for each particular type of special vehicle. The utility of the test cycles to optimize comfort is given to the accurate identification of the specific test needs, depending on the each vehicle.
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"H. Sapiens" as Ecologically Special: What Does Language Contribute?
ERIC Educational Resources Information Center
Ross, Don
2007-01-01
This paper inquires into the extent to which humans are specially constituted relative to other animals by their language. First a principled concept of evolutionary specialness is operationalized. Then it is agreed that humans satisfy the criteria for this sort of specialness in consequence of the kind of cultural evolution in which they have…
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Federal Register 2010, 2011, 2012, 2013, 2014
2013-11-06
... Special Emphasis Panel; Preserving Male Fertility After Cancer Therapy by Kyle E. Orwig. Date: November 14....929, Center for Medical Rehabilitation Research; 93.209, Contraception and Infertility Loan Repayment...
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5 CFR 9701.361 - Special skills payments.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 9701.361 Administrative Personnel DEPARTMENT OF HOMELAND SECURITY HUMAN RESOURCES MANAGEMENT SYSTEM (DEPARTMENT OF HOMELAND SECURITY-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF HOMELAND SECURITY HUMAN RESOURCES MANAGEMENT SYSTEM Pay and Pay Administration Special Payments § 9701.361 Special skills payments...
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Academic Specialization and Contemporary University Humanities Centers
ERIC Educational Resources Information Center
Brownley, Martine W.
2012-01-01
Given the academic specialization endemic today in humanities disciplines, some of the most important work of humanities centers has become promoting education about the humanities in general. After charting the rise of humanities centers in the US, three characteristics of centers that enable their advancement of larger concerns of the humanities…
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Non-formal Education in the Philippines: A Fundamental Step towards Lifelong Learning.
ERIC Educational Resources Information Center
Gonzales, Ma. Celeste T.; Pijano, Ma. Concepcion V.
In order to significantly contribute to human resource development, the Philippines must develop an integrated educational system of lifelong learning, with a special emphasis on non-formal education. Despite the value that is placed on formal, or sequential academic schooling, it is non-formal schooling that makes accessible the acquisition of…
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Mindfulness and Compassion in Human Development: Introduction to the Special Section
ERIC Educational Resources Information Center
Roeser, Robert W.; Eccles, Jacquelynne S.
2015-01-01
Research on contemplative practices (e.g., mindfulness or compassion training) is growing rapidly in the clinical, health and neuro-sciences, but almost none of this research takes an explicitly developmental life span perspective. At present, we know rather little about the naturalistic development of mindfulness or compassion in children and…
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ERIC Educational Resources Information Center
STEWART, EDWARD C.
SPECIAL TECHNIQUES AND CONTENT ARE BEING DEVELOPED TO SUPPLEMENT CURRENT AREA TRAINING PROGRAMS. SIMULATION WAS CHOSEN AS THE TECHNIQUE, AND EXERCISES WERE DEVELOPED WHOSE CONTENT EMPHASIZED THE AMERICAN CULTURE AND THE FOREIGN, HOST CULTURE. THESE EVOLVED AS A CONFRONTATION BETWEEN AMERICAN CULTURAL ASSUMPTIONS AND VALUES AND A CONTRASTING SET,…
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On quantum models of the human mind.
Wang, Hongbin; Sun, Yanlong
2014-01-01
Recent years have witnessed rapidly increasing interests in developing quantum theoretical models of human cognition. Quantum mechanisms have been taken seriously to describe how the mind reasons and decides. Papers in this special issue report the newest results in the field. Here we discuss why the two levels of commitment, treating the human brain as a quantum computer and merely adopting abstract quantum probability principles to model human cognition, should be integrated. We speculate that quantum cognition models gain greater modeling power due to a richer representation scheme. Copyright © 2013 Cognitive Science Society, Inc.
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Earth orbital teleoperator systems evaluation
NASA Technical Reports Server (NTRS)
Shields, N. L., Jr.; Slaughter, P. H.; Brye, R. G.; Henderson, D. E.
1979-01-01
The mechanical extension of the human operator to remote and specialized environments poses a series of complex operational questions. A technical and scientific team was organized to investigate these questions through conducting specific laboratory and analytical studies. The intent of the studies was to determine the human operator requirements for remotely manned systems and to determine the particular effects that various system parameters have on human operator performance. In so doing, certain design criteria based on empirically derived data concerning the ultimate control system, the human operator, were added to the Teleoperator Development Program.
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NASA Astrophysics Data System (ADS)
Battista, Christian; Evans, Tanya M.; Ngoon, Tricia J.; Chen, Tianwen; Chen, Lang; Kochalka, John; Menon, Vinod
2018-01-01
Cognitive development is thought to depend on the refinement and specialization of functional circuits over time, yet little is known about how this process unfolds over the course of childhood. Here we investigated growth trajectories of functional brain circuits and tested an interactive specialization model of neurocognitive development which posits that the refinement of task-related functional networks is driven by a shared history of co-activation between cortical regions. We tested this model in a longitudinal cohort of 30 children with behavioral and task-related functional brain imaging data at multiple time points spanning childhood and adolescence, focusing on the maturation of parietal circuits associated with numerical problem solving and learning. Hierarchical linear modeling revealed selective strengthening as well as weakening of functional brain circuits. Connectivity between parietal and prefrontal cortex decreased over time, while connectivity within posterior brain regions, including intra-hemispheric and inter-hemispheric parietal connectivity, as well as parietal connectivity with ventral temporal occipital cortex regions implicated in quantity manipulation and numerical symbol recognition, increased over time. Our study provides insights into the longitudinal maturation of functional circuits in the human brain and the mechanisms by which interactive specialization shapes children's cognitive development and learning.
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5 CFR 9701.333 - Special rate supplements.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Special rate supplements. 9701.333 Section 9701.333 Administrative Personnel DEPARTMENT OF HOMELAND SECURITY HUMAN RESOURCES MANAGEMENT... HUMAN RESOURCES MANAGEMENT SYSTEM Pay and Pay Administration Locality and Special Rate Supplements...
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The topography of primate retina: a study of the human, bushbaby, and new- and old-world monkeys.
Stone, J; Johnston, E
1981-02-20
The distribution of ganglion cells has been studied in the retinas of four primates: the prosimian bushbaby, the New-World squirrel monkey, the Old-World crab-eating cynamolgous monkey, and the human. The sizes of ganglion cell somas were also measured at a number of retinal locations and compared with similar measurements in the cat retina to test for the presence in primates of retinal specializations such as the visual streak, and for gradients in retinal structure, such as that between temporal and nasal retina. In all four primates, ganglion cell somas in peripheral retina ranged considerably in diameter (6-16 micrometer in the bushbaby, 8-22 micrometer in the squirrel monkey, 8-23 micrometer in the cynamolgous monkey, 8-26 micrometer in the human). It seems likely that the strong physiological correlates of soma size which have been described among cat retinal ganglion cells and among the relay cells of the macaque lateral geniculate nucleus are generally present in primates. In all four primates, evidence was also obtained of a visual streak specialization; the isodensity lines in ganglion cell density maps were horizontally elongated, and small-bodied ganglion cells were relatively more common in the region of the proposed streak than in other areas of peripheral retina. However, the visual streak seems less well developed than in the cat; among the four primate species examined it was best developed in the bushbaby, at least as assessed by the shape of the isodensity lines. All four primates showed a clear foveal specialization, but this feature seemed least developed in the bushbaby. At the fovea, ganglion cells are smaller in soma size than in peripheral retina; they also seemed more uniform in size, although some distinctly larger cells persist in the human and bushbaby. Soma size measurements also provided evidence of a difference between nasal and temporal areas of peripheral retina comparable to that reported for the cat and other species. Thus the primate retinas examined show features, such as the foveal specialization, which seem unique to them among mammals. They also show features, such as nasal-temporal differences in ganglion cell size, and (though weakly developed) a visual streak, which they have in common with other mammals with widely different phylogenetic histories.
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Virtual reality applications to automated rendezvous and capture
NASA Technical Reports Server (NTRS)
Hale, Joseph; Oneil, Daniel
1991-01-01
Virtual Reality (VR) is a rapidly developing Human/Computer Interface (HCI) technology. The evolution of high-speed graphics processors and development of specialized anthropomorphic user interface devices, that more fully involve the human senses, have enabled VR technology. Recently, the maturity of this technology has reached a level where it can be used as a tool in a variety of applications. This paper provides an overview of: VR technology, VR activities at Marshall Space Flight Center (MSFC), applications of VR to Automated Rendezvous and Capture (AR&C), and identifies areas of VR technology that requires further development.
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Understanding childbirth practices as an organizational cultural phenomenon: a conceptual framework
2013-01-01
Understanding the main values and beliefs that might promote humanized birth practices in the specialized hospitals requires articulating the theoretical knowledge of the social and cultural characteristics of the childbirth field and the relations between these and the institution. This paper aims to provide a conceptual framework allowing examination of childbirth practices through the lens of an organizational culture theory. A literature review performed to extrapolate the social and cultural factors contribute to birth practices and the factors likely overlap and mutually reinforce one another, instead of complying with the organizational culture of the birth place. The proposed conceptual framework in this paper examined childbirth patterns as an organizational cultural phenomenon in a highly specialized hospital, in Montreal, Canada. Allaire and Firsirotu’s organizational culture theory served as a guide in the development of the framework. We discussed the application of our conceptual model in understanding the influences of organizational culture components in the humanization of birth practices in the highly specialized hospitals and explained how these components configure both the birth practice and women’s choice in highly specialized hospitals. The proposed framework can be used as a tool for understanding the barriers and facilitating factors encountered birth practices in specialized hospitals. PMID:24215446
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1993-10-17
34, "in criteria, and scoring each applicable high resolution mode’, "within 10 minutes of element as I (satisfactory) or 0 power -on...everone ese, humanity. We humans are kowledg limited and we The specificatio concept development design, and ye the problem caused by that limitation...human task that is component, we would have 53=125 integration spaces. within the power of a normal, single, specialized As you can imagine this could
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[Medical education and the needs of human resources in the Hungarian health care system].
Szócska, G; Romics, L
2001-04-01
The strategic aims of medical education are discussing, from the view of the human resource demands in a modern healthcare system. The authors summarise the logical framework of medical functioning based on medical development and economical circumstances, and describe the role of personal skills in the daily work. Afterwards they discuss the development of medical education in the last three decades and present the tight connection between cognitive sciences and developing results mentioned above. The authors analyse some special points of the Hungarian medical faculties. In the conclusion they have shown the possibilities to support the Hungarian healthcare reform by the educational development.
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Animals in biomedical space research
NASA Astrophysics Data System (ADS)
Phillips, Robert W.
The use of experimental animals has been a major component of biomedical research progress. Using animals in space presents special problems, but also provides special opportunities. Rat and squirrel monkeys experiments have been planned in concert with human experiments to help answer fundamental questions concerning the effect of weightlessness on mammalian function. For the most part, these experiments focus on identified changes noted in humans during space flight. Utilizing space laboratory facilities, manipulative experiments can be completed while animals are still in orbit. Other experiments are designed to study changes in gravity receptor structure and function and the effect of weightlessness on early vertebrate development. Following these preliminary animals experiments on Spacelab Shuttle flights, longer term programs of animal investigation will be conducted on Space Station.
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[Orthodontics in the 21st century. Authoritative conference 21 May 1998].
Philippe, J
2000-01-01
The lecturer develops his ideas on the future of the special field emphasizing the importance that communications, perfection of new techniques and the realization of a more complete diagnosis concerning the human being as a whole, will assume.
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ERIC Educational Resources Information Center
Leonard, Gloria; And Others
1991-01-01
Four articles discuss library services to diverse user groups. Highlights include the Seattle Public Library's Human Diversity Training Program for library staff; cultural diversity at the University of Northern Colorado, including library collection development; information needs of physicists in special libraries; and library services to…
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Cortical Representations of Symbols, Objects, and Faces Are Pruned Back during Early Childhood
Pinel, Philippe; Dehaene, Stanislas; Pelphrey, Kevin A.
2011-01-01
Regions of human ventral extrastriate visual cortex develop specializations for natural categories (e.g., faces) and cultural artifacts (e.g., words). In adults, category-based specializations manifest as greater neural responses in visual regions of the brain (e.g., fusiform gyrus) to some categories over others. However, few studies have examined how these specializations originate in the brains of children. Moreover, it is as yet unknown whether the development of visual specializations hinges on “increases” in the response to the preferred categories, “decreases” in the responses to nonpreferred categories, or “both.” This question is relevant to a long-standing debate concerning whether neural development is driven by building up or pruning back representations. To explore these questions, we measured patterns of visual activity in 4-year-old children for 4 categories (faces, letters, numbers, and shoes) using functional magnetic resonance imaging. We report 2 key findings regarding the development of visual categories in the brain: 1) the categories “faces” and “symbols” doubly dissociate in the fusiform gyrus before children can read and 2) the development of category-specific responses in young children depends on cortical responses to nonpreferred categories that decrease as preferred category knowledge is acquired. PMID:20457691
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5 CFR 9701.344 - Special within-band increases.
Code of Federal Regulations, 2010 CFR
2010-01-01
... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Special within-band increases. 9701.344 Section 9701.344 Administrative Personnel DEPARTMENT OF HOMELAND SECURITY HUMAN RESOURCES MANAGEMENT... HUMAN RESOURCES MANAGEMENT SYSTEM Pay and Pay Administration Performance-Based Pay § 9701.344 Special...
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A Cultural-Histroical Approach to Learning and Teaching: New Pespectives on Advancing Development.
ERIC Educational Resources Information Center
Portes, Pedro R., Ed.
1993-01-01
This special issue is devoted to the cultural-historical school of thought about mental development based on the work of Lev Vygotsky. The research of Vygotsky addressed the sociocultural basis of higher-level cognitive functions, and ascribed an influential role to human speech and other mediational tools in originating changes in cognition and…
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ERIC Educational Resources Information Center
Choi, Sheena; Yeom, Minho
2010-01-01
The New University for Regional Innovation (NURI) is one of the South Korean Ministry of Education and Human Resources Development's key projects supporting regional universities. NURI aims to develop areas of specialization in regional universities and link universities to local industries. In 2004, the South Korean government pledged to invest…
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ERIC Educational Resources Information Center
Lynch, James, Ed.; Modgil, Celia, Ed.; Modgil, Sohan, Ed.
This volume focuses on the exclusion of two major populations, girls and those with special educational needs, from their human right to primary education. Contributions address the entitlement to primary education in a context broader than that of education alone, including health and nutritional dimensions, and exposing infringements of human…
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Can metaphysical values protect mountain wildlands from development damage?
Lawrence S. Hamilton; Jeneda Benally
2015-01-01
This paper addresses the question of whether spiritual, religious or cultural values held by humans for some wild mountain areas can protect these special places from developments that impair both these values and wild nature. The answer is sometimes yes, sometimes no, and sometimes a minimization of damage. Examples of each of these scenarios are briefly given, along...
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New Developments in Biotechnology: U.S. Investment in Biotechnology. [Special Report.
ERIC Educational Resources Information Center
Congress of the U.S., Washington, DC. Office of Technology Assessment.
Since the discovery of recombinant DNA in the early 1970s, biotechnology has become an essential tool for many industries. The potential of biotechnology to improve the Nation's health, food supply, and the quality of the environment leads logically to questions of whether current levels of investment in research and development, human resources,…
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Cisneros, Carolina; Díaz-Campos, Rocío Magdalena; Marina, Núria; Melero, Carlos; Padilla, Alicia; Pascual, Silvia; Pinedo, Celia; Trisán, Andrea
2017-01-01
This paper, developed by consensus of staff physicians of accredited asthma units for the management of severe asthma, presents information on the process and requirements for already-existing asthma units to achieve official accreditation by the Spanish Society of Pneumology and Thoracic Surgery (SEPAR). Three levels of specialized asthma care have been established based on available resources, which include specialized units for highly complex asthma, specialized asthma units, and basic asthma units. Regardless of the level of accreditation obtained, the distinction of “excellence” could be granted when more requirements in the areas of provision of care, technical and human resources, training in asthma, and teaching and research activities were met at each level. The Spanish experience in the process of accreditation of specialized asthma units, particularly for the care of patients with difficult-to-control asthma, may be applicable to other health care settings. PMID:28533690
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Luker, Gary D
2002-04-01
The AACR Special Conference on Molecular Imaging in Cancer: Linking Biology, Function, and Clinical Applications In Vivo, was held January 23-27, 2002, at the Contemporary Hotel, Walt Disney World, Orlando, FL. Co-Chairs David Piwnica-Worms, Patricia Price and Thomas Meade brought together researchers with diverse expertise in molecular biology, gene therapy, chemistry, engineering, pharmacology, and imaging to accelerate progress in developing and applying technologies for imaging specific cellular and molecular signals in living animals and humans. The format of the conference was the presentation of research that focused on basic and translational biology of cancer and current state-of-the-art techniques for molecular imaging in animal models and humans. This report summarizes the special conference on molecular imaging, highlighting the interfaces of molecular biology with animal models, instrumentation, chemistry, and pharmacology that are essential to convert the dreams and promise of molecular imaging into improved understanding, diagnosis, and management of cancer.
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Estalrrich, Almudena; Rosas, Antonio
2013-01-01
The developed cognitive capabilities for Homo sapiens seems to be the result of a specialized and lateralized brain, and as a result of this, humans display the highest degree of manual specialization or handedness among the primates. Studies regarding its emergence and distribution within the genus Homo show that handedness is present very early. The mode in which it was articulated and spread across the different species during the course of human evolution could provide information about our own cognitive capacities. Here we report the manual laterality attributed to eleven 49,000 old Neandertal individuals from El Sidrón cave (Spain), through the study of instrumental or cultural striations on the anterior dentition. Our results show a predominant pattern addressed to right-handers. These results fit within the modern human handedness distribution pattern and provide indirect evidence for behavior and brain lateralization on Neandertals. They support the early establishment of handedness in our genus. Moreover, the individual identified as Juvenile 1 (6–8 years old at death), displays the same striation pattern as the adult Neandertals from the sample, and thereby the ontogenic development of manual laterality in that Neandertal population seems to be similar to that of living modern humans. PMID:23671635
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Estalrrich, Almudena; Rosas, Antonio
2013-01-01
The developed cognitive capabilities for Homo sapiens seems to be the result of a specialized and lateralized brain, and as a result of this, humans display the highest degree of manual specialization or handedness among the primates. Studies regarding its emergence and distribution within the genus Homo show that handedness is present very early. The mode in which it was articulated and spread across the different species during the course of human evolution could provide information about our own cognitive capacities. Here we report the manual laterality attributed to eleven 49,000 old Neandertal individuals from El Sidrón cave (Spain), through the study of instrumental or cultural striations on the anterior dentition. Our results show a predominant pattern addressed to right-handers. These results fit within the modern human handedness distribution pattern and provide indirect evidence for behavior and brain lateralization on Neandertals. They support the early establishment of handedness in our genus. Moreover, the individual identified as Juvenile 1 (6-8 years old at death), displays the same striation pattern as the adult Neandertals from the sample, and thereby the ontogenic development of manual laterality in that Neandertal population seems to be similar to that of living modern humans.
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77 FR 64525 - National Eye Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2012-10-22
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Eye Institute... personal privacy. Name of Committee: National Eye Institute Special Emphasis Panel, NEI Career Development... Schaffner, Ph.D., Chief, Scientific Review Officer, Division of Extramural Research, National Eye Institute...
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Contemporary HRD Research: A Triarchy of Theoretical Perspectives and Their Prescriptions for HRD.
ERIC Educational Resources Information Center
Garavan, Thomas N.; Gunnigle, Patrick; Morley, Michael
2000-01-01
Presents key debates in human resource development. One table outlines the research focus and methodology of articles in this special issue. Another table compares three theoretical perspectives: capability driven, psychological contract, and learning organization. Contains 253 references. (SK)
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What Unites Us All: Establishing Special Education Teacher Education Universals
ERIC Educational Resources Information Center
Darling, Sharon M.; Dukes, Charles; Hall, Kalynn
2016-01-01
The theoretical base that supports human universals served as a model for proposing special education teacher education universals. The human universals model is explained and put forth as a basis for identifying special education teacher education universals. Twenty-four English language journals from different countries representing four…
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Code of Federal Regulations, 2010 CFR
2010-04-01
... FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION (CONTINUED) FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Special Dietary and Nutritional Additives § 172.395 Xylitol. Xylitol may be safely used in foods for special...
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Human Systems Engineering for Launch processing at Kennedy Space Center (KSC)
NASA Technical Reports Server (NTRS)
Henderson, Gena; Stambolian, Damon B.; Stelges, Katrine
2012-01-01
Launch processing at Kennedy Space Center (KSC) is primarily accomplished by human users of expensive and specialized equipment. In order to reduce the likelihood of human error, to reduce personal injuries, damage to hardware, and loss of mission the design process for the hardware needs to include the human's relationship with the hardware. Just as there is electrical, mechanical, and fluids, the human aspect is just as important. The focus of this presentation is to illustrate how KSC accomplishes the inclusion of the human aspect in the design using human centered hardware modeling and engineering. The presentations also explain the current and future plans for research and development for improving our human factors analysis tools and processes.
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Building human resources capability in health care: a global analysis of best practice--Part III.
Zairi, M
1998-01-01
This is the last part of a series of three papers which discussed very comprehensively best practice applications in human resource management by drawing special inferences to the healthcare context. It emerged from parts I and II that high performing organisations plan and intend to build sustainable capability through a systematic consideration of the human element as the key asset and through a continuous process of training, developing, empowering and engaging people in all aspects of organisational excellence. Part III brings this debate to a close by demonstrating what brings about organisational excellence and proposes a road map for effective human resource development and management, based on world class standards. Healthcare human resource professionals can now rise to the challenge and plan ahead for building organisational capability and sustainable performance.
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Chen, Xinyin
2015-02-01
Researchers have investigated the implications of social change for human development from different perspectives. The studies published in this special section were conducted within Greenfield's theoretical framework (2009). The findings concerning links between specific sociodemographic features (e.g., commercial activities, schooling) and individual cognition and social behaviour are particularly interesting because they tap the underlying forces that drive human development. To further understand the issues in these studies and in the field, a pluralist-constructive perspective is discussed, which emphasises the integration of diverse values and practices in both Western and non-Western societies and its effects on the development of sophisticated competencies in individual adaptation to the changing global community. In addition, several issues are highlighted and some suggestions are provided for future explorations in this field. © 2014 International Union of Psychological Science.
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The non-linear development of the right hemispheric specialization for human face perception.
Lochy, Aliette; de Heering, Adélaïde; Rossion, Bruno
2017-06-24
The developmental origins of human adults' right hemispheric specialization for face perception remain unclear. On the one hand, infant studies have shown a right hemispheric advantage for face perception. On the other hand, it has been proposed that the adult right hemispheric lateralization for face perception slowly emerges during childhood due to reading acquisition, which increases left lateralized posterior responses to competing written material (e.g., visual letters and words). Since methodological approaches used in infant and children typically differ when their face capabilities are explored, resolving this issue has been difficult. Here we tested 5-year-old preschoolers varying in their level of visual letter knowledge with the same fast periodic visual stimulation (FPVS) paradigm leading to strongly right lateralized electrophysiological occipito-temporal face-selective responses in 4- to 6-month-old infants (de Heering and Rossion, 2015). Children's face-selective response was quantitatively larger and differed in scalp topography from infants', but did not differ across hemispheres. There was a small positive correlation between preschoolers' letter knowledge and a non-normalized index of right hemispheric specialization for faces. These observations show that previous discrepant results in the literature reflect a genuine nonlinear development of the neural processes underlying face perception and are not merely due to methodological differences across age groups. We discuss several factors that could contribute to the adult right hemispheric lateralization for faces, such as myelination of the corpus callosum and reading acquisition. Our findings point to the value of FPVS coupled with electroencephalography to assess specialized face perception processes throughout development with the same methodology. Copyright © 2017 Elsevier Ltd. All rights reserved.
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77 FR 2737 - National Institute on Aging; Notice of Closed Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2012-01-19
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Aging... personal privacy. Name of Committee: National Institute on Aging Special Emphasis Panel; Development and....m. Agenda: To review and evaluate contract proposals. Place: National Institute on Aging, Gateway...
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Searching for Tomorrow's Innovators: Profiling Creative Adolescents
ERIC Educational Resources Information Center
Kerr, Barbara; McKay, Robyn
2013-01-01
Profiling may be a viable means of identifying those creative adolescents who can benefit from specialized guidance and exploration of science, technology, engineering, and mathematics (STEM) fields, arts, and human services. The experimenters developed 1 general and 5 specific profiles including interest, personality, and achievement variables…
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Liberia’s Post-War Development: Key Issues and U.S. Assistance
2010-05-25
former President Taylor was arrested in Nigeria and transferred to the Special Court for Sierra Leone (SCSL) to face war crimes charges. He was...50 War Crimes , Human Rights Cases, and Transitional Justice...56 Potential for War Crimes Tribunal in Liberia
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Oligodendroglia: metabolic supporters of axons.
Morrison, Brett M; Lee, Youngjin; Rothstein, Jeffrey D
2013-12-01
Axons are specialized extensions of neurons that are critical for the organization of the nervous system. To maintain function in axons that often extend some distance from the cell body, specialized mechanisms of energy delivery are likely to be necessary. Over the past decade, greater understanding of human demyelinating diseases and the development of animal models have suggested that oligodendroglia are critical for maintaining the function of axons. In this review, we discuss evidence for the vulnerability of neurons to energy deprivation, the importance of oligodendrocytes for axon function and survival, and recent data suggesting that transfer of energy metabolites from oligodendroglia to axons through monocarboxylate transporter 1 (MCT1) may be critical for the survival of axons. This pathway has important implications both for the basic biology of the nervous system and for human neurological disease. New insights into the role of oligodendroglial biology provide an exciting opportunity for revisions in nervous system biology, understanding myelin-based disorders, and therapeutics development. Copyright © 2013 Elsevier Ltd. All rights reserved.
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When does social learning become cultural learning?
Heyes, Cecilia
2017-03-01
Developmental research on selective social learning, or 'social learning strategies', is currently a rich source of information about when children copy behaviour, and who they prefer to copy. It also has the potential to tell us when and how human social learning becomes cultural learning; i.e. mediated by psychological mechanisms that are specialized, genetically or culturally, to promote cultural inheritance. However, this review article argues that, to realize its potential, research on the development of selective social learning needs more clearly to distinguish functional from mechanistic explanation; to achieve integration with research on attention and learning in adult humans and 'dumb' animals; and to recognize that psychological mechanisms can be specialized, not only by genetic evolution, but also by associative learning and cultural evolution. © 2015 John Wiley & Sons Ltd.
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ERIC Educational Resources Information Center
Prince, Christopher G.
2008-01-01
Developmental robotics has forwarded a range of models of development and behaviours. With the variety of systems that have been created, and with some of these approximating prominent human behaviours (e.g. joint attention, word learning, imitation), one may argue that developmental robotics has started to go past robotic models of earwigs…
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ERIC Educational Resources Information Center
Gordon, Edmund W., Ed.; Bridglall, Beatrice L., Ed.
2006-01-01
According to Gordon and Bridglall, the ability to learn is more of a developed human capacity than a fixed aptitude with which one is born. They argue that the emergence of academic ability is associated with exposure to specialized cultures that privilege the attitudes, knowledge, and skills that schools reward. Children who are born to and…
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Early Educators as Agents of Social Change for Inclusive Practices: An Action Research Study
ERIC Educational Resources Information Center
Rausch, Alissa
2016-01-01
The purpose of this study was to evaluate a new course developed for students in the early childhood education (ECE) graduate and/or licensure in early childhood special education (ECSE)--a Colorado teacher licensure program--in the School of Education and Human Development at CU Denver. The study explored graduate students' learning in a course…
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-25
... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: National Human Immunodeficiency Virus (HIV) Behavioral Surveillance, Funding Opportunity Announcement PS11-001; Initial Review Correction...
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A Probe into Key Points in the Planning and Design of Integrated Corridor at Large Civil Airports
NASA Astrophysics Data System (ADS)
Zhao, Qing
2018-05-01
If we compare an airport to our human body, all sorts of specialized pipelines and wires are to an airport as the vascular system and nervous system etc. to the human body, where each functional zone connecting the airport serves each major system of airport and provides “throughput like the function of driving out the processed for the new” and “central control and transmission function”. Guided by the master plan and the concept of progressive development of airports, it is critical to map out a plan to link near-term and long-term development of supporting utilities. The role and effect of integrated corridor is of significance to the construction of multi-runway large-sized new airports or to the expansion of an airport costing tens of billions. In view of the features of the fast growing civil aviation sector in China, this thesis argues for the necessity to plan for and build integrated corridor at large airports, suggests doing research on integrated corridor at the project consulting stage by drawing upon available airport design experiences and case studies and combining the plan for public utilities (or special plan), and analyzes and outlines key points in integrated corridor design based on special requirements and industrial standards for civil airport management.
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Hemispheric asymmetry in auditory processing of speech envelope modulations in prereading children.
Vanvooren, Sophie; Poelmans, Hanne; Hofmann, Michael; Ghesquière, Pol; Wouters, Jan
2014-01-22
The temporal envelope of speech is an important cue contributing to speech intelligibility. Theories about the neural foundations of speech perception postulate that the left and right auditory cortices are functionally specialized in analyzing speech envelope information at different time scales: the right hemisphere is thought to be specialized in processing syllable rate modulations, whereas a bilateral or left hemispheric specialization is assumed for phoneme rate modulations. Recently, it has been found that this functional hemispheric asymmetry is different in individuals with language-related disorders such as dyslexia. Most studies were, however, performed in adults and school-aged children, and only a little is known about how neural auditory processing at these specific rates manifests and develops in very young children before reading acquisition. Yet, studying hemispheric specialization for processing syllable and phoneme rate modulations in preliterate children may reveal early neural markers for dyslexia. In the present study, human cortical evoked potentials to syllable and phoneme rate modulations were measured in 5-year-old children at high and low hereditary risk for dyslexia. The results demonstrate a right hemispheric preference for processing syllable rate modulations and a symmetric pattern for phoneme rate modulations, regardless of hereditary risk for dyslexia. These results suggest that, while hemispheric specialization for processing syllable rate modulations seems to be mature in prereading children, hemispheric specialization for phoneme rate modulation processing may still be developing. These findings could have important implications for the development of phonological and reading skills.
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1990-01-01
in that the with this hypothesis are the many reports (e.g., Adler - crossed-disparity system does appear to develop first Grinberg & Stark 1978... Rodman et al. 1986) that survives as independent of hemispheric asymmetries and additive to striate lesions critically depends on the superior...Perfomance. IRAAI human brain. No longer can visual cortical physiology Adler -Grinberg, D. & Stark, L. (1978) Eye movements, scanpaths, and dyslexia
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[Theoretic and practical content of the clinical embryology].
Trávník, P; Hampl, A; Hűttelová, R; Malenovská, A; Priesnitz, J; Rejthar, D; Záková, J
2013-08-01
Clinical embryology is in whole Europe respected health care specialization. The specialists in this field are certified by the European Society of Human Reproduction and Embryology (ESHRE). In the Czech Republic the specialization has been formally established by the Government Order No 31/ 2010 after 30 years unformal existence. Concurrently with the wide development of new techniques in assisted reproduction, there is necessary to define the content of clinical embryology as a health care, scientific and educational discipline. The definition authorized by the Committee of Association of Reproductive Embryology (ARE) is given in this article..
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Bayesian statistical techniques have proven useful in clinical and environmental epidemiological applications to evaluate and integrate available information, and in regulatory applications such as the National Ambient Air Quality Assessment for Nitrogen Oxides. A recent special...
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48 CFR 1335.006 - Contracting methods and contract type.
Code of Federal Regulations, 2010 CFR
2010-10-01
... SPECIAL CATEGORIES OF CONTRACTING RESEARCH AND DEVELOPMENT CONTRACTING 1335.006 Contracting methods and... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contracting methods and... research services under the contract might involve the use of human subjects. The provision is mandatory...
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78 FR 24761 - National Institute of Dental & Craniofacial Research; Notice of Closed Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2013-04-26
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Dental... clearly unwarranted invasion of personal privacy. Name of Committee: National Institute of Dental and Craniofacial Research Special Emphasis Panel; Design and Development of Novel Dental Composite Restorative...
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45 CFR 1308.4 - Purpose and scope of disabilities service plan.
Code of Federal Regulations, 2010 CFR
2010-10-01
... DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD START PROGRAM HEAD START PROGRAM PERFORMANCE STANDARDS ON SERVICES FOR CHILDREN WITH... strategies for meeting the special needs of children with disabilities and their parents. The purposes of...
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45 CFR 1308.4 - Purpose and scope of disabilities service plan.
Code of Federal Regulations, 2014 CFR
2014-10-01
... DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD START PROGRAM HEAD START PROGRAM PERFORMANCE STANDARDS ON SERVICES FOR CHILDREN WITH... strategies for meeting the special needs of children with disabilities and their parents. The purposes of...
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45 CFR 1308.4 - Purpose and scope of disabilities service plan.
Code of Federal Regulations, 2013 CFR
2013-10-01
... DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD START PROGRAM HEAD START PROGRAM PERFORMANCE STANDARDS ON SERVICES FOR CHILDREN WITH... strategies for meeting the special needs of children with disabilities and their parents. The purposes of...
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45 CFR 1308.4 - Purpose and scope of disabilities service plan.
Code of Federal Regulations, 2012 CFR
2012-10-01
... DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD START PROGRAM HEAD START PROGRAM PERFORMANCE STANDARDS ON SERVICES FOR CHILDREN WITH... strategies for meeting the special needs of children with disabilities and their parents. The purposes of...
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45 CFR 1308.4 - Purpose and scope of disabilities service plan.
Code of Federal Regulations, 2011 CFR
2011-10-01
... DEVELOPMENT SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION FOR CHILDREN, YOUTH AND FAMILIES, HEAD START PROGRAM HEAD START PROGRAM PERFORMANCE STANDARDS ON SERVICES FOR CHILDREN WITH... strategies for meeting the special needs of children with disabilities and their parents. The purposes of...
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Problems of Geography as General Education.
ERIC Educational Resources Information Center
Harper, Robert A.
The increasing interdependency and regional specialization of today's world demand a new approach to the teaching of introductory geography courses. By focusing on the interrelationship of physical, cultural, and economic geography, a course for general education students can foster development of the geographic perspective on human systems needed…
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Centers for Enhancement of Education.
ERIC Educational Resources Information Center
Biggerstaff, Ed
The Center for Enhancement of Education organizes seven specialized centers within the School of Education and Human Services to provide faculty and students with the opportunity for research, development, and public service activities that complement and supplement classroom teaching. Each of the seven centers stresses one of the following…
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1993--Twenty-Fifth Annual National Council on Family Relations Videotape Competition.
ERIC Educational Resources Information Center
Gentry, Deborah; And Others
1994-01-01
Lists and annotates winning entries in 1993 National Council on Family Relations Videotape Competition in categories of substance abuse, aging, social issues, divorce/remarriage, families with special needs, family violence, human development, reproduction and family planning, marital/family issues, mental health, nontraditional families,…
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75 FR 81631 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-28
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of... Infectious Diseases Special Emphasis Panel. Development of Therapeutics Products for Biodefense. Date... 3126, MSC-7616, Bethesda, MD 20892-7616. 301-451-2671. [email protected] . Name of Committee...
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75 FR 19982 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2010-04-16
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of... Infectious Diseases Special Emphasis Panel; Radiation/Nuclear Medical Countermeasure Product Development..., Division of Extramural Activities, NIAID/ NIH/DHHS, 6700B Rockledge Drive, MSC 7616, Room 3130, Bethesda...
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The Importance of Context in Development and Application of Ecosystem Services Production Functions
The task of estimating ecosystem service production and delivery deserves special attention. When approached as a function of land cover at any given time, context driven facets of ecosystem service production, delivery, and resulting effects on human well-being can be overlooke...
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ERIC Educational Resources Information Center
Costa, Celio Juvenal
2000-01-01
Reflects on the current tendency in Brazilian higher education for greater and greater specialization, particularly in human sciences and in medicine. Calls for less specialization and a more historic and general preparation, especially in teacher education. (BT)
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NASA Technical Reports Server (NTRS)
Fern, Lisa; Rorie, Conrad; Shively, Jay
2015-01-01
This presentation provides an overview of the work the Human Systems Integration (HSI) sub-project has done on detect and avoid (DAA) displays while working on the UAS Integration into the NAS project. Much of the work has been used to support the ongoing development of minimum operational performance standards (MOPS) for UAS by RTCA Special Committee 228. The design and results of three different human-in-the-loop simulations are discussed, with particular emphasis on the role of the UAS pilot in the Self Separation Timeline.
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Introduction to the Special Section on Epigenetics.
Lester, Barry M; Conradt, Elisabeth; Marsit, Carmen
2016-01-01
Epigenetics provides the opportunity to revolutionize our understanding of the role of genetics and the environment in explaining human behavior, although the use of epigenetics to study human behavior is just beginning. In this introduction, the authors present the basics of epigenetics in a way that is designed to make this exciting field accessible to a wide readership. The authors describe the history of human behavioral epigenetic research in the context of other disciplines and graphically illustrate the burgeoning of research in the application of epigenetic methods and principles to the study of human behavior. The role of epigenetics in normal embryonic development and the influence of biological and environmental factors altering behavior through epigenetic mechanisms and developmental programming are discussed. Some basic approaches to the study of epigenetics are reviewed. The authors conclude with a discussion of challenges and opportunities, including intervention, as the field of human behavioral epigenetics continue to grow. © 2016 The Authors. Child Development © 2016 Society for Research in Child Development, Inc.
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The Role of Lunar Development in Human Exploration of the Solar System
NASA Technical Reports Server (NTRS)
Mendell, Wendell W.
1999-01-01
Human exploration of the solar system can be said to have begun with the Apollo landings on the Moon. The Apollo Project was publicly funded with the narrow technical objective of landing human beings on the Moon. The transportation and life support systems were specialized technical designs, developed in a project management environment tailored to that objective. Most scenarios for future human exploration assume a similar long-term commitment of public funds to a narrowly focused project managed by a large, monolithic organization. Advocates of human exploration of space have not yet been successful in generating the political momentum required to initiate such a project to go to the Moon or to Mars. Alternative scenarios of exploration may relax some or all of the parameters of organizational complexity, great expense, narrow technical focus, required public funding, and control by a single organization. Development of the Moon using private investment is quite possibly a necessary condition for alternative scenarios to succeed.
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Propagating Humanized BLT Mice for the Study of Human Immunology and Immunotherapy.
Smith, Drake J; Lin, Levina J; Moon, Heesung; Pham, Alexander T; Wang, Xi; Liu, Siyuan; Ji, Sunjong; Rezek, Valerie; Shimizu, Saki; Ruiz, Marlene; Lam, Jennifer; Janzen, Deanna M; Memarzadeh, Sanaz; Kohn, Donald B; Zack, Jerome A; Kitchen, Scott G; An, Dong Sung; Yang, Lili
2016-12-15
The humanized bone marrow-liver-thymus (BLT) mouse model harbors a nearly complete human immune system, therefore providing a powerful tool to study human immunology and immunotherapy. However, its application is greatly limited by the restricted supply of human CD34 + hematopoietic stem cells and fetal thymus tissues that are needed to generate these mice. The restriction is especially significant for the study of human immune systems with special genetic traits, such as certain human leukocyte antigen (HLA) haplotypes or monogene deficiencies. To circumvent this critical limitation, we have developed a method to quickly propagate established BLT mice. Through secondary transfer of bone marrow cells and human thymus implants from BLT mice into NSG (NOD/SCID/IL-2Rγ -/- ) recipient mice, we were able to expand one primary BLT mouse into a colony of 4-5 proBLT (propagated BLT) mice in 6-8 weeks. These proBLT mice reconstituted human immune cells, including T cells, at levels comparable to those of their primary BLT donor mouse. They also faithfully inherited the human immune cell genetic traits from their donor BLT mouse, such as the HLA-A2 haplotype that is of special interest for studying HLA-A2-restricted human T cell immunotherapies. Moreover, an EGFP reporter gene engineered into the human immune system was stably passed from BLT to proBLT mice, making proBLT mice suitable for studying human immune cell gene therapy. This method provides an opportunity to overcome a critical hurdle to utilizing the BLT humanized mouse model and enables its more widespread use as a valuable preclinical research tool.
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Tso, Kai-Yuen; Lee, Sau Dan; Lo, Kwok-Wai; Yip, Kevin Y
2014-12-23
Patient-derived tumor xenografts in mice are widely used in cancer research and have become important in developing personalized therapies. When these xenografts are subject to DNA sequencing, the samples could contain various amounts of mouse DNA. It has been unclear how the mouse reads would affect data analyses. We conducted comprehensive simulations to compare three alignment strategies at different mutation rates, read lengths, sequencing error rates, human-mouse mixing ratios and sequenced regions. We also sequenced a nasopharyngeal carcinoma xenograft and a cell line to test how the strategies work on real data. We found the "filtering" and "combined reference" strategies performed better than aligning reads directly to human reference in terms of alignment and variant calling accuracies. The combined reference strategy was particularly good at reducing false negative variants calls without significantly increasing the false positive rate. In some scenarios the performance gain of these two special handling strategies was too small for special handling to be cost-effective, but it was found crucial when false non-synonymous SNVs should be minimized, especially in exome sequencing. Our study systematically analyzes the effects of mouse contamination in the sequencing data of human-in-mouse xenografts. Our findings provide information for designing data analysis pipelines for these data.
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The Climate Science Special Report: Detection and Attribution
NASA Astrophysics Data System (ADS)
Wehner, M. F.
2017-12-01
The Climate Science Special Report reiterates previous findings about the human influence on global mean surface air temperature with the statement "…it is extremely likely that human activities, especially emissions of greenhouse gases, are the dominant cause of the observed warming since the mid 20th century. For the warming over the last century, there is no convincing alternative explanation supported by the extent of the observational evidence." This is a statement made with high confidence and supported by multiple lines of evidence. The report also assesses the latest developments in the field of probabilistic extreme event attribution—the quantification of the influence of anthropogenic climate change on individual extreme weather events—with a focus on those recent events within the United States that have been analyzed. Thirty different events within the US are reported on including heat waves, cold snaps, wet seasons, individual storms and droughts. Most but not all of the individual US events studied revealed an influence from human induced changes to the climate system.
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Evidence of two distinct functionally specialized fibroblast lineages in breast stroma.
Morsing, Mikkel; Klitgaard, Marie Christine; Jafari, Abbas; Villadsen, René; Kassem, Moustapha; Petersen, Ole William; Rønnov-Jessen, Lone
2016-11-03
The terminal duct lobular unit (TDLU) is the most dynamic structure in the human breast and the putative site of origin of human breast cancer. Although stromal cells contribute to a specialized microenvironment in many organs, this component remains largely understudied in the human breast. We here demonstrate the impact on epithelium of two lineages of breast stromal fibroblasts, one of which accumulates in the TDLU while the other resides outside the TDLU in the interlobular stroma. The two lineages are prospectively isolated by fluorescence activated cell sorting (FACS) based on different expression levels of CD105 and CD26. The characteristics of the two fibroblast lineages are assessed by immunocytochemical staining and gene expression analysis. The differentiation capacity of the two fibroblast populations is determined by exposure to specific differentiating conditions followed by analysis of adipogenic and osteogenic differentiation. To test whether the two fibroblast lineages are functionally imprinted by their site of origin, single cell sorted CD271 low /MUC1 high normal breast luminal epithelial cells are plated on fibroblast feeders for the observation of morphological development. Epithelial structure formation and polarization is shown by immunofluorescence and digitalized quantification of immunoperoxidase-stained cultures. Lobular fibroblasts are CD105 high /CD26 low while interlobular fibroblasts are CD105 low /CD26 high . Once isolated the two lineages remain phenotypically stable and functionally distinct in culture. Lobular fibroblasts have properties in common with bone marrow derived mesenchymal stem cells and they specifically convey growth and branching morphogenesis of epithelial progenitors. Two distinct functionally specialized fibroblast lineages exist in the normal human breast, of which the lobular fibroblasts have properties in common with mesenchymal stem cells and support epithelial growth and morphogenesis. We propose that lobular fibroblasts constitute a specialized microenvironment for human breast luminal epithelial progenitors, i.e. the putative precursors of breast cancer.
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WiFi-Based Real-Time Calibration-Free Passive Human Motion Detection.
Gong, Liangyi; Yang, Wu; Man, Dapeng; Dong, Guozhong; Yu, Miao; Lv, Jiguang
2015-12-21
With the rapid development of WLAN technology, wireless device-free passive human detection becomes a newly-developing technique and holds more potential to worldwide and ubiquitous smart applications. Recently, indoor fine-grained device-free passive human motion detection based on the PHY layer information is rapidly developed. Previous wireless device-free passive human detection systems either rely on deploying specialized systems with dense transmitter-receiver links or elaborate off-line training process, which blocks rapid deployment and weakens system robustness. In the paper, we explore to research a novel fine-grained real-time calibration-free device-free passive human motion via physical layer information, which is independent of indoor scenarios and needs no prior-calibration and normal profile. We investigate sensitivities of amplitude and phase to human motion, and discover that phase feature is more sensitive to human motion, especially to slow human motion. Aiming at lightweight and robust device-free passive human motion detection, we develop two novel and practical schemes: short-term averaged variance ratio (SVR) and long-term averaged variance ratio (LVR). We realize system design with commercial WiFi devices and evaluate it in typical multipath-rich indoor scenarios. As demonstrated in the experiments, our approach can achieve a high detection rate and low false positive rate.
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WiFi-Based Real-Time Calibration-Free Passive Human Motion Detection †
Gong, Liangyi; Yang, Wu; Man, Dapeng; Dong, Guozhong; Yu, Miao; Lv, Jiguang
2015-01-01
With the rapid development of WLAN technology, wireless device-free passive human detection becomes a newly-developing technique and holds more potential to worldwide and ubiquitous smart applications. Recently, indoor fine-grained device-free passive human motion detection based on the PHY layer information is rapidly developed. Previous wireless device-free passive human detection systems either rely on deploying specialized systems with dense transmitter-receiver links or elaborate off-line training process, which blocks rapid deployment and weakens system robustness. In the paper, we explore to research a novel fine-grained real-time calibration-free device-free passive human motion via physical layer information, which is independent of indoor scenarios and needs no prior-calibration and normal profile. We investigate sensitivities of amplitude and phase to human motion, and discover that phase feature is more sensitive to human motion, especially to slow human motion. Aiming at lightweight and robust device-free passive human motion detection, we develop two novel and practical schemes: short-term averaged variance ratio (SVR) and long-term averaged variance ratio (LVR). We realize system design with commercial WiFi devices and evaluate it in typical multipath-rich indoor scenarios. As demonstrated in the experiments, our approach can achieve a high detection rate and low false positive rate. PMID:26703612
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NASA Astrophysics Data System (ADS)
Kapiarsa, A. B.; Sariffuddin, S.
2018-02-01
Local knowledge in disaster management should not be neglected in developing community resilience. The circular relation between humans and their living habitat and community social relation have developed the local knowledge namely specialized knowledge, shared knowledge, and common knowledge. Its correlation with community-based disaster management has become an important discussion specially to answer can local knowledge underlie community-based disaster risk reduction concept development? To answer this question, this research used mix-method. Interview and crosstab method for 73 respondents with 90% trust rate were used to determine the correlation between local knowledge and community characteristics. This research found out that shared knowledge dominated community local knowledge (77%). While common knowledge and specialized knowledge were sequentially 8% and 15%. The high score of shared value (77%) indicated that local knowledge was occurred in household level and not yet indicated in community level. Shared knowledge was found in 3 phases of the resilient community in dealing with disaster, namely mitigation, emergency response, and recovery phase. This research, therefore, has opened a new scientific discussion on the self-help concept in community-help concept in CBDRM concept development in Indonesia.
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Adult Learning and the Teaching of Evaluation: A Study of an Experiential Learning Project.
ERIC Educational Resources Information Center
Preskill, Hallie
The paper describes the development of a course on evaluation in business and industry, offered as part of a Master's program in Human Resource Development. Since the average age of the students was 36, special emphasis was placed on structuring the class to increase relevance to the students' working lives and to ways adults learn best. A brief…
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ERIC Educational Resources Information Center
Paley, Karen Surman
2008-01-01
The author had the pleasure of being in an academic setting where students of color were in the majority. That was the summer of 2004 as she observed African-American Literature 1900-Present, a writing intensive class in the Special Program in Talent Development (SPTD) at the University of Rhode Island (URI). The author wants to tell the story of…
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Convention on the rights of the child: promoting human rights in Islamic day schools in Indonesia.
Rivin, Beth E
2011-09-01
In recent years, rights-based approaches to health are changing the perspective and work of actors in the development sector. This article describes an NGO program that translates theory into practice by integrating human rights education and human rights principles into primary school health programs in Jakarta, Indonesia. Uplift International, an NGO affiliated with the University of Washington School of Law, aims to improve the rights of urban, poor children through teacher and parent training, uniquely designed for the madrasah (Islamic religious day schools) community. The school program links child rights and child health through human rights education and human rights-based methodologies. The Uplift International program is in its fourth year and plans to expand in scope. Positive outcomes include significant notice by Indonesian Government Ministries. Moreover, there is support from the new Indonesian Special Envoy to the UN for Millennium Development Goals (MDGs).
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Medical humanities: lineage, excursionary sketch and rationale.
Hurwitz, Brian
2013-11-01
Medical Humanities the journal started life in 2000 as a special edition of the JME. However, the intellectual taproots of the medical humanities as a field of enquiry can be traced to two developments: calls made in the 1920s for the development of multidisciplinary perspectives on the sciences that shed historical light on their assumptions, methods and practices; refusals to assimilate all medical phenomena to a biomedical worldview. Medical humanities the term stems from a desire to situate the significance of medicine as a product of culture. But despite growing usage over half a century the term defies a unifying encapsulation and continues to conjure up a multitude of discourse communities, including scholars working at the interfaces of health and humanities, arts and health, and medical education and bioethics. The field is intellectually capacious and polymorphous, forming and reforming around critical new research questions and teaching tasks spanning disciplines.
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Evolution of the Human Nervous System Function, Structure, and Development.
Sousa, André M M; Meyer, Kyle A; Santpere, Gabriel; Gulden, Forrest O; Sestan, Nenad
2017-07-13
The nervous system-in particular, the brain and its cognitive abilities-is among humans' most distinctive and impressive attributes. How the nervous system has changed in the human lineage and how it differs from that of closely related primates is not well understood. Here, we consider recent comparative analyses of extant species that are uncovering new evidence for evolutionary changes in the size and the number of neurons in the human nervous system, as well as the cellular and molecular reorganization of its neural circuits. We also discuss the developmental mechanisms and underlying genetic and molecular changes that generate these structural and functional differences. As relevant new information and tools materialize at an unprecedented pace, the field is now ripe for systematic and functionally relevant studies of the development and evolution of human nervous system specializations. Copyright © 2017 Elsevier Inc. All rights reserved.
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Recent technology products from Space Human Factors research
NASA Technical Reports Server (NTRS)
Jenkins, James P.
1991-01-01
The goals of the NASA Space Human Factors program and the research carried out concerning human factors are discussed with emphasis given to the development of human performance models, data, and tools. The major products from this program are described, which include the Laser Anthropometric Mapping System; a model of the human body for evaluating the kinematics and dynamics of human motion and strength in microgravity environment; an operational experience data base for verifying and validating the data repository of manned space flights; the Operational Experience Database Taxonomy; and a human-computer interaction laboratory whose products are the display softaware and requirements and the guideline documents and standards for applications on human-computer interaction. Special attention is given to the 'Convoltron', a prototype version of a signal processor for synthesizing the head-related transfer functions.
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Social is special: A normative framework for teaching with and learning from evaluative feedback.
Ho, Mark K; MacGlashan, James; Littman, Michael L; Cushman, Fiery
2017-10-01
Humans often attempt to influence one another's behavior using rewards and punishments. How does this work? Psychologists have often assumed that "evaluative feedback" influences behavior via standard learning mechanisms that learn from environmental contingencies. On this view, teaching with evaluative feedback involves leveraging learning systems designed to maximize an organism's positive outcomes. Yet, despite its parsimony, programs of research predicated on this assumption, such as ones in developmental psychology, animal behavior, and human-robot interaction, have had limited success. We offer an explanation by analyzing the logic of evaluative feedback and show that specialized learning mechanisms are uniquely favored in the case of evaluative feedback from a social partner. Specifically, evaluative feedback works best when it is treated as communicating information about the value of an action rather than as a form of reward to be maximized. This account suggests that human learning from evaluative feedback depends on inferences about communicative intent, goals and other mental states-much like learning from other sources, such as demonstration, observation and instruction. Because these abilities are especially developed in humans, the present account also explains why evaluative feedback is far more widespread in humans than non-human animals. Copyright © 2017 Elsevier B.V. All rights reserved.
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75 FR 9907 - National Heart, Lung, and Blood Institute; Notice of Closed Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2010-03-04
... Institute Special Emphasis Panel, Development of Blood Donor Tests for the Presence of Human Babesia... Call.) Contact Person: Youngsuk Oh, PhD, Scientific Review Officer, Review Branch/DERA, National Heart..., DC 20037. Contact Person: Mark Roltsch, PhD, Scientific Review Officer, Review Branch/DERA, National...
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New Approaches to a Subject of Anthropocentric Linguistics
ERIC Educational Resources Information Center
Lee, Valentine S.; Tumanova, Ainakul B.; Salkhanova, Zhanat H.
2016-01-01
The article studies theoretical issues of modern anthropocentric paradigm of scientific knowledge from the history of anthropocentric linguistics development as a special field of language science. The purpose of this study is to answer the question about human influence on the semiotic system. The material result is the unification of specific…
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78 FR 56905 - National Eye Institute; Notice of Closed Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-09-16
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Eye Institute; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U... personal privacy. Name of Committee: National Eye Institute Special Emphasis Panel; NEI Career Development...
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HIV Prevention and AIDS Education: Resources for Special Educators.
ERIC Educational Resources Information Center
Byrom, Elizabeth, Ed.; Katz, Ginger, Ed.
This guide was developed out of a 5-year project aimed at preventing the transmission of the human immunodeficiency virus (HIV) by promoting HIV prevention and AIDS (acquired immunodeficiency syndrome) education in school health programs. This document includes recommendations of a January, 1989 forum which addressed HIV prevention education for…
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75 FR 41212 - Center for Scientific Review; Notice of Closed Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2010-07-15
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5... Committee: Center for Scientific Review Special Emphasis Panel; Early Embryo Development Pluripotency. Date...
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Humanistic Traditions, East and West: Convergence and Divergence
ERIC Educational Resources Information Center
Kato, Morimichi
2016-01-01
The term "humanism" is Western in origin. It denotes the tradition that places special emphasis on cultivation of letters for education. In the West, this tradition was originated with sophists and Isocrates, established by Cicero, and was developed by Renaissance humanists. East Asia, however, also has its own humanistic traditions with…
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Thoughts on Amending China's "Vocational Education Law"
ERIC Educational Resources Information Center
Liu, Yufeng
2014-01-01
An analysis of China's existing "Vocational Education Law" finds that it does not focus entirely on human development or career advancement, nor does it fully reflect the special requirements of vocational education. It does not align the obligations, rights, and liabilities of vocational education stakeholders. The law does not specify…
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Mental Retardation FY 1983. Special Report to Congress.
ERIC Educational Resources Information Center
National Inst. of Child Health and Human Development (NIH), Bethesda, MD.
The paper reviews mental retardation research activities of the National Institute of Child Health and Human Development (NICHHD) and the National Institute of Neurological and Communicative Disorders and Stroke (NINCDS). Research activities are cited to illustrate the scope of NICHHD's efforts in a variety of biomedial areas. Activities are…
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75 FR 80511 - National Institute on Drug Abuse; Notice of Closed Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-22
... unwarranted invasion of personal privacy. Name of Committee: National Institute on Drug Abuse Special Emphasis Panel; Development of Alternate Drug Delivery Dosage Forms for Drug Abuse Studies. Date: January 7, 2011... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Drug...
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75 FR 31796 - Center for Scientific Review; Notice of Closed Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2010-06-04
... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center for Scientific Review; Notice of Closed Meetings Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5...: Center for Scientific Review Special Emphasis Panel; Tooth Development, Mobility and Mineralization. Date...
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Challenges Facing Adoption of Information Communication Technology in African Universities
ERIC Educational Resources Information Center
Murgor, Titus Kiptoo
2015-01-01
A significant number of the universities and higher educational institutions have adopted the latest technology and implemented it productively, for the development of skilled human resource in respective area of specialization, as part of their responsibility. Information and communication Technology (ICT) has grown tremendously around the globe…
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76 FR 69743 - The Development and Evaluation of Human Cytomegalovirus Vaccines; Public Workshop
Federal Register 2010, 2011, 2012, 2013, 2014
2011-11-09
... immune systems. Congenital HCMV infection causes mental retardation, learning disabilities, hearing loss, vision loss, and other disabilities. Patients undergoing stem cell or solid-organ transplants are at... available basis beginning at 8 a.m. If you need special accommodations due to a disability, please contact...
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ERIC Educational Resources Information Center
Walker, W. Hugh
The arid areas of the world, especially the Middle East and North Africa, need to develop an educational system that is attuned to the needs of the people in order to improve human and institutional competencies required to solve social and economic problems. Since arid areas have special characteristics, it is necessary to find applicable…
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Prologue: Developing Evidence-based Practices and Research Collaborations in School Settings.
ERIC Educational Resources Information Center
Apel, Kenn
2001-01-01
This introductory article discusses factors that have led to changes in speech-language pathology practices, including a better and broader understanding of the human communication process, revised federal guidelines and regulations for special education and related services, and a strong desire to encourage scientific pursuit through…
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Rudolph, Michael C; Young, Bridget E; Jackson, Kristina Harris; Krebs, Nancy F; Harris, William S; MacLean, Paul S
2016-12-01
Accurate assessment of the long chain polyunsaturated fatty acid (LC-PUFA) content of human milk (HM) provides a powerful means to evaluate the FA nutrient status of breastfed infants. The conventional standard for FA composition analysis of HM is liquid extraction, trans-methylation, and analyte detection resolved by gas chromatography. This standard approach requires fresh or frozen samples, storage in deep freeze, organic solvents, and specialized equipment in processing and analysis. Further, HM collection is often impractical for many studies in the free living environment, particularly for studies in developing countries. In the present study, we compare a novel and more practical approach to sample collection and processing that involves the spotting and drying ~50 μL of HM on a specialized paper stored and transported at ambient temperatures until analysis. Deming regression indicated the two methods aligned very well for all LC-PUFA and the abundant HM FA. Additionally, strong correlations (r > 0.85) were observed for DHA, ARA, EPA, linoleic (LA), and alpha-linolenic acids (ALA), which are of particular interest to the health of the developing infant. Taken together, our data suggest this more practical and inexpensive method of collection, storage, and transport of HM milk samples could dramatically facilitate studies of HM, as well as understanding its lipid composition influences on human health and development.
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Superhydrophobic Natural and Artificial Surfaces—A Structural Approach
Avrămescu, Roxana-Elena; Ghica, Mihaela Violeta; Dinu-Pîrvu, Cristina; Prisada, Răzvan; Popa, Lăcrămioara
2018-01-01
Since ancient times humans observed animal and plants features and tried to adapt them according to their own needs. Biomimetics represents the foundation of many inventions from various fields: From transportation devices (helicopter, airplane, submarine) and flying techniques, to sports’ wear industry (swimming suits, scuba diving gear, Velcro closure system), bullet proof vests made from Kevlar etc. It is true that nature provides numerous noteworthy models (shark skin, spider web, lotus leaves), referring both to the plant and animal kingdom. This review paper summarizes a few of “nature’s interventions” in human evolution, regarding understanding of surface wettability and development of innovative special surfaces. Empirical models are described in order to reveal the science behind special wettable surfaces (superhydrophobic /superhydrophilic). Materials and methods used in order to artificially obtain special wettable surfaces are described in correlation with plants’ and animals’ unique features. Emphasis is placed on joining superhydrophobic and superhydrophilic surfaces, with important applications in cell culturing, microorganism isolation/separation and molecule screening techniques. Bio-inspired wettability is presented as a constitutive part of traditional devices/systems, intended to improve their characteristics and extend performances. PMID:29789488
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Superhydrophobic Natural and Artificial Surfaces-A Structural Approach.
Avrămescu, Roxana-Elena; Ghica, Mihaela Violeta; Dinu-Pîrvu, Cristina; Prisada, Răzvan; Popa, Lăcrămioara
2018-05-22
Since ancient times humans observed animal and plants features and tried to adapt them according to their own needs. Biomimetics represents the foundation of many inventions from various fields: From transportation devices (helicopter, airplane, submarine) and flying techniques, to sports' wear industry (swimming suits, scuba diving gear, Velcro closure system), bullet proof vests made from Kevlar etc. It is true that nature provides numerous noteworthy models (shark skin, spider web, lotus leaves), referring both to the plant and animal kingdom. This review paper summarizes a few of "nature's interventions" in human evolution, regarding understanding of surface wettability and development of innovative special surfaces. Empirical models are described in order to reveal the science behind special wettable surfaces (superhydrophobic /superhydrophilic). Materials and methods used in order to artificially obtain special wettable surfaces are described in correlation with plants' and animals' unique features. Emphasis is placed on joining superhydrophobic and superhydrophilic surfaces, with important applications in cell culturing, microorganism isolation/separation and molecule screening techniques. Bio-inspired wettability is presented as a constitutive part of traditional devices/systems, intended to improve their characteristics and extend performances.
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What's Special about Human Imitation? A Comparison with Enculturated Apes.
Subiaul, Francys
2016-07-07
What, if anything, is special about human imitation? An evaluation of enculturated apes' imitation skills, a "best case scenario" of non-human apes' imitation performance, reveals important similarities and differences between this special population of apes and human children. Candidates for shared imitation mechanisms include the ability to imitate various familiar transitive responses and object-object actions that involve familiar tools. Candidates for uniquely derived imitation mechanisms include: imitating novel transitive actions and novel tool-using responses as well as imitating opaque or intransitive gestures, regardless of familiarity. While the evidence demonstrates that enculturated apes outperform non-enculturated apes and perform more like human children, all apes, regardless of rearing history, generally excel at imitating familiar, over-rehearsed responses and are poor, relative to human children, at imitating novel, opaque or intransitive responses. Given the similarities between the sensory and motor systems of preschool age human children and non-human apes, it is unlikely that differences in sensory input and/or motor-output alone explain the observed discontinuities in imitation performance. The special rearing history of enculturated apes-including imitation-specific training-further diminishes arguments suggesting that differences are experience-dependent. Here, it is argued that such differences are best explained by distinct, specialized mechanisms that have evolved for copying rules and responses in particular content domains. Uniquely derived social and imitation learning mechanisms may represent adaptations for learning novel communicative gestures and complex tool-use. Given our species' dependence on both language and tools, mechanisms that accelerated learning in these domains are likely to have faced intense selective pressures, starting with the earliest of human ancestors.
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Code of Federal Regulations, 2010 CFR
2010-07-01
... purpose space may the Department of Health and Human Services lease? 102-73.195 Section 102-73.195 Public... Delegations § 102-73.195 What types of special purpose space may the Department of Health and Human Services lease? The Department of Health and Human Services is delegated authority to lease laboratories (lease...
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Zdravkovic, A; Dordevic, S; Andelković, N
1975-01-01
The contemporary role and tasks of hygienic-epidemiological service are the outcome of the significant social, demographic, economic and health changes as a result of general social development. Natural phenomena such as elemental catastrophies, pollution of human environment, permanent threat of breaking out war at different places, all these set special tasks and determine the role of hygienic-epidemiological service. The contemporary role of the hygienic-epidemiological service is to provide scientific approach to the efficient solving of topical hygienic-epidemiological problems originated in newly-made ecological conditions, disturbed balance in nature, and also in changes of social structure of population. The tasks of the hygienic-epidemiological service are classified according to the role and purpose of each institution and according to the territory where the institution is situated, all these depending on situation (regular or special). In regular situation they have the tasks which are concerned with protection of the living environment and they include prevention of the mass deseases, contagious and other. In special situation they are concerned with catastrophies such as floods, earthquakes, breaking out of grow epidemics, occurence of quarantine diseases and other, and their aim is to prevent or at least to lessen the consequences caused by these catastrophies.
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NASA Technical Reports Server (NTRS)
Koontz, Steven L.; Rojdev, Kristina; Valle, Gerard D.; Zipay, John J.; Atwell, William S.
2013-01-01
Space radiation effects mitigation has been identified as one of the highest priority technology development areas for human space flight in the NASA Strategic Space Technology Investment Plan (Dec. 2012). In this paper we review the special features of space radiation that lead to severe constraints on long-term (more than 180 days) human flight operations outside Earth's magnetosphere. We then quantify the impacts of human space radiation dose limits on spacecraft engineering design and development, flight program architecture, as well as flight program schedule and cost. A new Deep Space Habitat (DSH) concept, the hybrid inflatable habitat, is presented and shown to enable a flexible, affordable approach to long term manned interplanetary flight today.
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-02-22
... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Human Immunodeficiency Virus (HIV) Prevention Projects for Young Men of Color Who Have Sex With Men and Young Transgender Persons of Color...
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Creating History, Telling Stories, and Making Special: Portfolios, Scrapbooks, and Sketchbooks
ERIC Educational Resources Information Center
Delacruz, Elizabeth; Bales, Sandy
2010-01-01
All human communications are a form of storytelling about some aspect of the world. They are shaped by human personality and grounded in their historical contexts. This article considers commonalities and differences among three kinds of artful human communications that appeared to people as a special kind of storytelling: (1) preservice art…
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Human skin dendritic cells in health and disease.
Haniffa, Muzlifah; Gunawan, Merry; Jardine, Laura
2015-02-01
Dendritic cells (DCs) are specialized antigen presenting cells abundant in peripheral tissues such as skin where they function as immune sentinels. Skin DCs migrate to draining lymph node where they interact with naïve T cells to induce immune responses to microorganisms, vaccines, tumours and self-antigens. In this review, we present the key historical developments and recent advances in human skin DC research. We also integrate the current understanding on the origin and functional specializations of DC subsets in healthy skin with findings in inflammatory skin diseases focusing on psoriasis and atopic eczema. A comprehensive understanding of the dynamic changes in DC subsets in health and disease will form a strong foundation to facilitate the clinical translation of DC-based therapeutic and vaccination strategies. Copyright © 2014 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.
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NASA Technical Reports Server (NTRS)
Schutte, Paul C.; Goodrich, Kenneth H.; Cox, David E.; Jackson, Bruce; Palmer, Michael T.; Pope, Alan T.; Schlecht, Robin W.; Tedjojuwono, Ken K.; Trujillo, Anna C.; Williams, Ralph A.;
2007-01-01
This paper reviews current and emerging operational experiences, technologies, and human-machine interaction theories to develop an integrated flight system concept designed to increase the safety, reliability, and performance of single-pilot operations in an increasingly accommodating but stringent national airspace system. This concept, know as the Naturalistic Flight Deck (NFD), uses a form of human-centered automation known as complementary-automation (or complemation) to structure the relationship between the human operator and the aircraft as independent, collaborative agents having complimentary capabilities. The human provides commonsense knowledge, general intelligence, and creative thinking, while the machine contributes specialized intelligence and control, extreme vigilance, resistance to fatigue, and encyclopedic memory. To support the development of the NFD, an initial Concept of Operations has been created and selected normal and non-normal scenarios are presented in this document.
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Mullineaux, Paula Y; DiLalla, Lisabeth Fisher
2015-07-01
Nearly all aspects of human development are influenced by genetic and environmental factors, which conjointly shape development through several gene-environment interplay mechanisms. More recently, researchers have begun to examine the influence of genetic factors on peer and family relationships across the pre-adolescent and adolescent time periods. This article introduces the special issue by providing a critical overview of behavior genetic methodology and existing research demonstrating gene-environment processes operating on the link between peer and family relationships and adolescent adjustment. The overview is followed by a summary of new research studies, which use genetically informed samples to examine how peer and family environment work together with genetic factors to influence behavioral outcomes across adolescence. The studies in this special issue provide further evidence of gene-environment interplay through innovative behavior genetic methodological approaches across international samples. Results from the quantitative models indicate environmental moderation of genetic risk for coercive adolescent-parent relationships and deviant peer affiliation. The molecular genetics studies provide support for a gene-environment interaction differential susceptibility model for dopamine regulation genes across positive and negative peer and family environments. Overall, the findings from the studies in this special issue demonstrate the importance of considering how genes and environments work in concert to shape developmental outcomes during adolescence.
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Assessing the spatial relationship between fixation and foveal specializations.
Wilk, Melissa A; Dubis, Adam M; Cooper, Robert F; Summerfelt, Phyllis; Dubra, Alfredo; Carroll, Joseph
2017-03-01
Increased cone photoreceptor density, an avascular zone (FAZ), and the displacement of inner retinal neurons to form a pit are distinct features of the human fovea. As the fovea provides the majority of our vision, appreciating how these anatomical specializations are related is important for understanding foveal development, normal visual function, and retinal disease. Here we evaluated the relationship between these specializations and their location relative to the preferred retinal locus of fixation (PRL). We measured foveal pit volume, FAZ area, peak cone density, and location of the PRL in 22 subjects with normal vision using optical coherence tomography and adaptive optics scanning light ophthalmoscopy. Foveal pit volume was positively correlated with FAZ area; however, peak cone density was not correlated with pit volume. In addition, there was no systematic offset of the location of any of these specializations relative to PRL, and there was no correlation between the magnitude of the offset from PRL and the corresponding foveal specialization measurements (pit volume, FAZ area, peak cone density). The standard deviation of our PRL measurements was consistent with previous measurements of fixational stability. These data provide insight into the sequence of events during foveal development and may have implications for visual function and retinal disease. Copyright © 2016 Elsevier Ltd. All rights reserved.
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Biosynthesis and biological functions of terpenoids in plants.
Tholl, Dorothea
2015-01-01
Terpenoids (isoprenoids) represent the largest and most diverse class of chemicals among the myriad compounds produced by plants. Plants employ terpenoid metabolites for a variety of basic functions in growth and development but use the majority of terpenoids for more specialized chemical interactions and protection in the abiotic and biotic environment. Traditionally, plant-based terpenoids have been used by humans in the food, pharmaceutical, and chemical industries, and more recently have been exploited in the development of biofuel products. Genomic resources and emerging tools in synthetic biology facilitate the metabolic engineering of high-value terpenoid products in plants and microbes. Moreover, the ecological importance of terpenoids has gained increased attention to develop strategies for sustainable pest control and abiotic stress protection. Together, these efforts require a continuous growth in knowledge of the complex metabolic and molecular regulatory networks in terpenoid biosynthesis. This chapter gives an overview and highlights recent advances in our understanding of the organization, regulation, and diversification of core and specialized terpenoid metabolic pathways, and addresses the most important functions of volatile and nonvolatile terpenoid specialized metabolites in plants.
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The renewal of humanism in psychotherapy: a roundtable discussion.
Schneider, Kirk J; Längle, Alfried
2012-12-01
This special section highlights the renewal of humanism in psychotherapy. For the purposes of this special section, humanism is defined as a philosophical perspective whose subject matter is the whole human being. In psychotherapy, humanism places special emphasis on the personal, interpersonal, and contextual dimensions of therapy and on clients' reflections on their relationship with self, others, and the larger psychosocial world. The contributors to this special section-Bruce Wampold, David Elkins, Steven Hayes, Robert Stolorow, Jurgen Kriz, Lillian Comas-Diaz, and the authors of this introduction-are each leaders in their respective therapeutic specialties: research and training, cognitive-behavioral therapy, psychoanalytic therapy, European therapy, and multicultural therapy. In the manner of a "roundtable," each contributor was asked to provide a short article on the renewal of humanism in his or her respective specialty followed by brief comments on the initial round of articles. The conclusion of these reflections is that the renewal of humanism is a viable and growing phenomenon among the leading specialty areas of psychotherapy. The corollary conclusion is that although many theoretical and practical questions remain, humanism is (1) a foundational element of therapeutic effectiveness; (2) a pivotal (and needed) dimension of therapeutic training; and (3) a critical contributor to societal well-being. (c) 2012 APA, all rights reserved.
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Analyzing Robotic Kinematics Via Computed Simulations
NASA Technical Reports Server (NTRS)
Carnahan, Timothy M.
1992-01-01
Computing system assists in evaluation of kinematics of conceptual robot. Displays positions and motions of robotic manipulator within work cell. Also displays interactions between robotic manipulator and other objects. Results of simulation displayed on graphical computer workstation. System includes both off-the-shelf software originally developed for automotive industry and specially developed software. Simulation system also used to design human-equivalent hand, to model optical train in infrared system, and to develop graphical interface for teleoperator simulation system.
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Convergent transcriptional specializations in the brains of humans and song-learning birds
Pfenning, Andreas R.; Hara, Erina; Whitney, Osceola; Rivas, Miriam V.; Wang, Rui; Roulhac, Petra L.; Howard, Jason T.; Wirthlin, Morgan; Lovell, Peter V.; Ganapathy, Ganeshkumar; Mouncastle, Jacquelyn; Moseley, M. Arthur; Thompson, J. Will; Soderblom, Erik J.; Iriki, Atsushi; Kato, Masaki; Gilbert, M. Thomas P.; Zhang, Guojie; Bakken, Trygve; Bongaarts, Angie; Bernard, Amy; Lein, Ed; Mello, Claudio V.; Hartemink, Alexander J.; Jarvis, Erich D.
2015-01-01
Song-learning birds and humans share independently evolved similarities in brain pathways for vocal learning that are essential for song and speech and are not found in most other species. Comparisons of brain transcriptomes of song-learning birds and humans relative to vocal nonlearners identified convergent gene expression specializations in specific song and speech brain regions of avian vocal learners and humans. The strongest shared profiles relate bird motor and striatal song-learning nuclei, respectively, with human laryngeal motor cortex and parts of the striatum that control speech production and learning. Most of the associated genes function in motor control and brain connectivity. Thus, convergent behavior and neural connectivity for a complex trait are associated with convergent specialized expression of multiple genes. PMID:25504733
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Deciphering the Mechanism of Alternative Cleavage and Polyadenylation in Mantle Cell Lymphoma (MCL)
2013-10-01
also has human firefly luciferase cloned within the same reporter system allowing for intra-plasmid normalization of transfection eliminating problems...collaboration with Dr. Wei Li, a Bioinformaticist from Baylor College of Medicine whose lab specializes in developing complex algorithms to analyze genome...wide sequencing data. Dr. Wei Li and his postdoctoral fellow, Dr. Zheng Xia developed a customized algorithm that is able to detect and quantify
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Specialized metabolites from the microbiome in health and disease
Sharon, Gil; Garg, Neha; Debelius, Justine; Knight, Rob; Dorrestein, Pieter C.; Mazmanian, Sarkis K.
2015-01-01
The microbiota, and the genes that comprise its microbiome, play key roles in human health. Host-microbe interactions affect immunity, metabolism, development, and behavior, and dysbiosis of gut bacteria contributes to disease. Despite advances in correlating changes in the microbiota with various conditions, specific mechanisms of host-microbiota signaling remain largely elusive. We discuss the synthesis of microbial metabolites, their absorption, and potential physiological effects on the host. We propose that the effects of specialized metabolites may explain present knowledge gaps linking the gut microbiota to biological host mechanisms during initial colonization, and in health and disease. PMID:25440054
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What’s Special about Human Imitation? A Comparison with Enculturated Apes
Subiaul, Francys
2016-01-01
What, if anything, is special about human imitation? An evaluation of enculturated apes’ imitation skills, a “best case scenario” of non-human apes’ imitation performance, reveals important similarities and differences between this special population of apes and human children. Candidates for shared imitation mechanisms include the ability to imitate various familiar transitive responses and object–object actions that involve familiar tools. Candidates for uniquely derived imitation mechanisms include: imitating novel transitive actions and novel tool-using responses as well as imitating opaque or intransitive gestures, regardless of familiarity. While the evidence demonstrates that enculturated apes outperform non-enculturated apes and perform more like human children, all apes, regardless of rearing history, generally excel at imitating familiar, over-rehearsed responses and are poor, relative to human children, at imitating novel, opaque or intransitive responses. Given the similarities between the sensory and motor systems of preschool age human children and non-human apes, it is unlikely that differences in sensory input and/or motor-output alone explain the observed discontinuities in imitation performance. The special rearing history of enculturated apes—including imitation-specific training—further diminishes arguments suggesting that differences are experience-dependent. Here, it is argued that such differences are best explained by distinct, specialized mechanisms that have evolved for copying rules and responses in particular content domains. Uniquely derived social and imitation learning mechanisms may represent adaptations for learning novel communicative gestures and complex tool-use. Given our species’ dependence on both language and tools, mechanisms that accelerated learning in these domains are likely to have faced intense selective pressures, starting with the earliest of human ancestors. PMID:27399786
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Marshall Space Flight Center's Virtual Reality Applications Program 1993
NASA Technical Reports Server (NTRS)
Hale, Joseph P., II
1993-01-01
A Virtual Reality (VR) applications program has been under development at the Marshall Space Flight Center (MSFC) since 1989. Other NASA Centers, most notably Ames Research Center (ARC), have contributed to the development of the VR enabling technologies and VR systems. This VR technology development has now reached a level of maturity where specific applications of VR as a tool can be considered. The objectives of the MSFC VR Applications Program are to develop, validate, and utilize VR as a Human Factors design and operations analysis tool and to assess and evaluate VR as a tool in other applications (e.g., training, operations development, mission support, teleoperations planning, etc.). The long-term goals of this technology program is to enable specialized Human Factors analyses earlier in the hardware and operations development process and develop more effective training and mission support systems. The capability to perform specialized Human Factors analyses earlier in the hardware and operations development process is required to better refine and validate requirements during the requirements definition phase. This leads to a more efficient design process where perturbations caused by late-occurring requirements changes are minimized. A validated set of VR analytical tools must be developed to enable a more efficient process for the design and development of space systems and operations. Similarly, training and mission support systems must exploit state-of-the-art computer-based technologies to maximize training effectiveness and enhance mission support. The approach of the VR Applications Program is to develop and validate appropriate virtual environments and associated object kinematic and behavior attributes for specific classes of applications. These application-specific environments and associated simulations will be validated, where possible, through empirical comparisons with existing, accepted tools and methodologies. These validated VR analytical tools will then be available for use in the design and development of space systems and operations and in training and mission support systems.
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Amortization Schedules in Human Growth and Developments Investments: The Case for Social Mutation.
ERIC Educational Resources Information Center
Weber, Robert E.
Decision makers, policy makers, and influential special interest groups typically view many appropriations for programs that will help the poor, the handicapped, social deviants, etc. as mere expenditures and not as investment which produce substantial results. This paper sets forth several cases which illustrate that people can be an attractive…
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Maternal and Child Health, FY 1983. Special Report to Congress.
ERIC Educational Resources Information Center
National Inst. of Child Health and Human Development (NIH), Bethesda, MD.
Providing several examples of current research efforts, this report describes the research on maternal and child health supported by the National Institute of Child Health and Human Development (NICHD). The Institute conducts a coordinated program of research and research training to advance knowledge related to pregnancy and maternal health,…
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Belief-Desire Reasoning as a Process of Selection
ERIC Educational Resources Information Center
Leslie, Alan M.; German, Tim P.; Polizzi, Pamela
2005-01-01
Human learning may depend upon domain specialized mechanisms. A plausible example is rapid, early learning about the thoughts and feelings of other people. A major achievement in this domain, at about age four in the typically developing child, is the ability to solve problems in which the child attributes false beliefs to other people and…
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Dennis A. Vinton; Donald E. Hawkins
1977-01-01
This review of literature is intended to promote awareness of the needs of the 15 percent of the nation's children and youth who are afflicted with some form of handicap. It is imperative that those who design children's programs that utilize natural environments understand the special problems of handicapped children.
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75 FR 81556 - Solicitation of New Safe Harbors and Special Fraud Alerts
Federal Register 2010, 2011, 2012, 2013, 2014
2010-12-28
...: Notice of intent to develop regulations. SUMMARY: In accordance with section 205 of the Health Insurance.... Section 205 of the Health Insurance Portability and Accountability Act of 1996 Section 205 of the Health... DEPARTMENT OF HEALTH AND HUMAN SERVICES Office of Inspector General 42 CFR Part 1001 Solicitation...
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Internationalisation as a Key Dimension to Teacher Education
ERIC Educational Resources Information Center
Dooly, Melinda; Villanueva, Maria
2006-01-01
The European Union has recognized the need for promoting social and political change through education. Special emphasis has been placed on the role of schools in personal and human development, along with the need for greater understanding of the diversity which makes up the European Union and throughout the world. This means that teachers are…
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The Vatican and Unesco Link Efforts for World Literacy
ERIC Educational Resources Information Center
Ryan, Leo V., Brother
1970-01-01
The problem of functional literacy has been recognized as a moral issue and offers a special challenge to religious authorities. Founded at the Vatican level in March 1969, the Committee on Human Development was commissioned to promote and animate efforts in: (a) basic education; (b) leadership training; (c) vocational education; (d) opinion…
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Neural Correlates of Human and Monkey Face Processing in 9-Month-Old Infants
ERIC Educational Resources Information Center
Scott, Lisa S.; Shannon, Robert W.; Nelson, Charles A.
2006-01-01
Behavioral and electrophysiological evidence suggests a gradual, experience-dependent specialization of cortical face processing systems that takes place largely in the 1st year of life. To further investigate these findings, event-related potentials (ERPs) were collected from typically developing 9-month-old infants presented with pictures of…
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International Perspectives on Homophobic and Transphobic Bullying in Schools
ERIC Educational Resources Information Center
Kosciw, Joseph G.; Pizmony-Levy, Oren
2016-01-01
There has been increasing international attention to the experiences of lesbian, gay, bisexual, and transgender (LGBT) students in schools, and a growing concern regarding anti-LGBT violence and bias directed at youth as a serious human rights issue and barrier to global development goals. This special issue highlights research that has been done…
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Effects of Inclusion on Students with and without Special Educational Needs Reviewed
ERIC Educational Resources Information Center
Ruijs, Nienke M.; Peetsma, Thea T. D.
2009-01-01
In many countries, education policies are shifting towards inclusive education. Human rights have always been an important argument for this development, but the effects on students should be an important factor when designing policies. In this review, therefore, literature on the effects of inclusion on both students with and without special…
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Code of Federal Regulations, 2012 CFR
2012-01-01
... DEPARTMENT OF HEALTH AND HUMAN SERVICES SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES § 5501.107 Teaching, speaking and writing by special Government...
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Code of Federal Regulations, 2014 CFR
2014-01-01
... DEPARTMENT OF HEALTH AND HUMAN SERVICES SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES § 5501.107 Teaching, speaking and writing by special Government...
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Code of Federal Regulations, 2013 CFR
2013-01-01
... DEPARTMENT OF HEALTH AND HUMAN SERVICES SUPPLEMENTAL STANDARDS OF ETHICAL CONDUCT FOR EMPLOYEES OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES § 5501.107 Teaching, speaking and writing by special Government...
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-10-13
... will also include a review of PCAH ongoing programming for youth arts and humanities learning, special... special accommodations due to a disability, please contact the Office of AccessAbility, National Endowment...
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Kant and the development of the human and cultural sciences.
Makkreel, Rudolf A
2008-12-01
Starting with Kant's doubts about psychology as a natural science capable of explaining human behavior, several alternative attempts to conceive of human life, culture and history are examined. Kant proposes an anthropology that will be a commonly useful human science rather than a universally valid natural science. This anthropology relates to philosophy as a mode of world-cognition. Special attention is given to how Kant's theory of right can help define our appropriate place in a communal world. The different ways in which Wilhelm Dilthey and Hermann Cohen respond to Kant's idea of legitimate appropriation are also considered. The various tasks that descriptive elucidation, explanation, reflective understanding, characterization and interpretation can perform for the human and cultural sciences are examined throughout the essay.
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Modeling Niemann Pick type C1 using human embryonic and induced pluripotent stem cells.
Ordoñez, M Paulina; Steele, John W
2017-02-01
Data generated in Niemann Pick type C1 (NPC1) human embryonic and human induced pluripotent stem cell derived neurons complement on-going studies in animal models and provide the first example, in disease-relevant human cells, of processes that underlie preferential neuronal defects in a NPC1. Our work and that of other investigators in human neurons derived from stem cells highlight the importance of performing rigorous mechanistic studies in relevant cell types to guide drug discovery and therapeutic development, alongside of existing animal models. Through the use of human stem cell-derived models of disease, we can identify and discover or repurpose drugs that revert early events that lead to neuronal failure in NPC1. Together with the study of disease pathogenesis and efficacy of therapies in animal models, these strategies will fulfill the promise of stem cell technology in the development of new treatments for human diseases. This article is part of a Special Issue entitled SI: Exploiting human neurons. Copyright © 2016 Elsevier B.V. All rights reserved.
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Advances in graphonomics: studies on fine motor control, its development and disorders.
Van Gemmert, Arend W A; Teulings, Hans-Leo
2006-10-01
During the past 20 years graphonomic research has become a major contributor to the understanding of human movement science. Graphonomic research investigates the relationship between the planning and generation of fine motor tasks, in particular, handwriting and drawing. Scientists in this field are at the forefront of using new paradigms to investigate human movement. The 16 articles in this special issue of Human Movement Science show that the field of graphonomics makes an important contribution to the understanding of fine motor control, motor development, and movement disorders. Topics discussed include writer's cramp, multiple sclerosis, Parkinson's disease, schizophrenia, drug-induced parkinsonism, dopamine depletion, dysgraphia, motor development, developmental coordination disorder, caffeine, alertness, arousal, sleep deprivation, visual feedback transformation and suppression, eye-hand coordination, pen grip, pen pressure, movement fluency, bimanual interference, dominant versus non-dominant hand, tracing, freehand drawing, spiral drawing, reading, typewriting, and automatic segmentation.
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Management of Service Projects in Support of Space Flight Research
NASA Technical Reports Server (NTRS)
Love, J.
2009-01-01
Goal:To provide human health and performance countermeasures, knowledge, technologies, and tools to enable safe, reliable, and productive human space exploration . [HRP-47051] Specific Objectives: 1) Develop capabilities, necessary countermeasures, and technologies in support of human space exploration, focusing on mitigating the highest risks to human health and performance. 2) Define and improve human spaceflight medical, environmental, and human factors standards. 3) Develop technologies that serve to reduce medical and environmental risks, to reduce human systems resource requirements (mass, volume, power, data, etc.) and to ensure effective human-system integration across exploration systems. 4) Ensure maintenance of Agency core competencies necessary to enable risk reduction in the following areas: A. Space medicine B. Physiological and behavioral effects of long duration spaceflight on the human body C. Space environmental effects, including radiation, on human health and performance D. Space "human factors" [HRP-47051]. Service projects can form integral parts of research-based project-focused programs to provide specialized functions. Traditional/classic project management methodologies and agile approaches are not mutually exclusive paradigms. Agile strategies can be combined with traditional methods and applied in the management of service projects functioning in changing environments. Creative collaborations afford a mechanism for mitigation of constrained resource limitations.
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Normal development and growth of the human neurocranium and cranial base.
Friede, H
1981-01-01
The literature on normal development and growth of certain areas of the human head is reviewed, starting with the early induction of the desmal neurocranium. the development of the brain capsule with its dural reinforcement bands and their connection with the basicranium is discussed, as is the primordial chondrocranium, including its bone replacement. Growth of the calvaria and the three cranial fossae is also analysed. Special interest is focused on the anterior fossa, as knowledge of the growth in this area is very important for an understanding of pathogenesis and possibilities of treating premature craniosynostosis. Finally it is stressed that close observation of the effects of treatment on this pathology may increase our knowledge of normal growth.
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Calzo, Jerel P; Bogart, Laura M; Francis, Evelyn; Kornetsky, Susan Z; Winkler, Sabune J; Kaberry, Julie
2016-01-01
Engaging community partners as co-investigators in community-based participatory research (CBPR) requires certification in the rules, ethics, and principles governing research. Despite developments in making human research protection trainings more convenient and standardized (eg, self-paced Internet modules), time constraints and the structure of the content (which may favor academic audiences) may hinder the training of community partners. This paper is motivated by a case example in which academic and community partners, and stakeholders of a community-based organization actively engaged the leadership of a pediatric hospital-based institutional review board (IRB) in implementing a brief, community-responsive human subjects training session. A 2-hour, discussion-based human subjects training was developed via collaborations between the IRB and the community and academic partners. Interviews with trainees and facilitators after the training were used to evaluate its acceptability and possible future applications. Local IRBs have the potential to assist community partners in building sufficient knowledge of human subjects research protections to engage in specific projects, thereby expediting the progress of vital research to address community needs. We propose the need for developing truncated human subjects education materials to train and certify community partners, and creating formally organized entities within academic and medical institutions that specialize in community-based research to guide the development and implementation of alternative human subjects training certification opportunities for community partners.
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Translating human biology (introduction to special issue).
Brewis, Alexandra A; Mckenna, James J
2015-01-01
Introducing a special issue on "Translating Human Biology," we pose two basic questions: Is human biology addressing the most critical challenges facing our species? How can the processes of translating our science be improved and innovated? We analyze articles published in American Journal of Human Biology from 2004-2013, and find there is very little human biological consideration of issues related to most of the core human challenges such as water, energy, environmental degradation, or conflict. There is some focus on disease, and considerable focus on food/nutrition. We then introduce this special volume with reference to the following articles that provide exemplars for the process of how translation and concern for broader context and impacts can be integrated into research. Human biology has significant unmet potential to engage more fully in translation for the public good, through consideration of the topics we focus on, the processes of doing our science, and the way we present our domain expertise. © 2014 Wiley Periodicals, Inc.
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Human Classification Based on Gestural Motions by Using Components of PCA
NASA Astrophysics Data System (ADS)
Aziz, Azri A.; Wan, Khairunizam; Za'aba, S. K.; B, Shahriman A.; Adnan, Nazrul H.; H, Asyekin; R, Zuradzman M.
2013-12-01
Lately, a study of human capabilities with the aim to be integrated into machine is the famous topic to be discussed. Moreover, human are bless with special abilities that they can hear, see, sense, speak, think and understand each other. Giving such abilities to machine for improvement of human life is researcher's aim for better quality of life in the future. This research was concentrating on human gesture, specifically arm motions for differencing the individuality which lead to the development of the hand gesture database. We try to differentiate the human physical characteristic based on hand gesture represented by arm trajectories. Subjects are selected from different type of the body sizes, and then acquired data undergo resampling process. The results discuss the classification of human based on arm trajectories by using Principle Component Analysis (PCA).
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Tusé, Daniel
2011-03-01
Guidelines issued by regulatory agencies for the development of plant-made pharmaceutical (PMP) products provide criteria for product manufacturing and characterization, safety determination, containment and mitigation of environmental risks. Features of plant-made products do not always enable an easy fit within the criteria subscribed to by regulators. The unconventional nature of plant-based manufacturing processes and peculiarities of plant biology relative to that of traditional biological production systems have led to special considerations in the regulatory scrutiny of PMP. Presented in this review are case studies of two plant-made autologous (patient-specific) cancer vaccines, the nature of which introduced challenges to conventional and standardized development and preclinical evaluation routes. The rationale presented to FDA by the sponsors of each vaccine to build consensus and obtain variances to existing guidelines is discussed. While development of many plant-made biologics can be accomplished within the existing regulatory framework, the development of specialized products can be defended with rational arguments based on strong science.
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Darton College Customized Nursing Program for the Fort Benning Community and Research Project
2015-01-01
learning if transferred out of the Fort Benning area. • Creating special review resources provided for use on netbooks or computers so that students...stated that without this added flexibility their progression towards graduation would not have been possible. Netbook /laptop versions of nursing core...for the development of netbook /laptop version of Human Growth and Development (PSYC 2103); however this was modified when the nursing curriculum
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Modeling the relationship between the environment and human experiences.
Vink, P; Bazley, C; Jacobs, K
2016-08-12
Within this special issue, different aspects of the environment are studied: aspects that are distant from the human body, close to the body and touching the human body. Consequently, different human senses are involved in these studies as well as the different consequences and effects on the brain and human behaviour. This special issue also highlights many remaining questions about the effects and relationships between environments and human beings and the need for more studies and research. In particular, future studies are needed that address long-term effects and the effects of the combinations of elements which provide comfort or discomfort.
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Chelomina, G N
2017-01-01
The review summarizes the results of first genomic and transcriptomic investigations of the liver fluke Clonorchis sinensis (Opisthorchiidae, Trematoda). The studies mark the dawn of the genomic era for opisthorchiids, which cause severe hepatobiliary diseases in humans and animals. Their results aided in understanding the molecular mechanisms of adaptation to parasitism, parasite survival in mammalian biliary tracts, and genome dynamics in the individual development and the development of parasite-host relationships. Special attention is paid to the achievements in studying the codon usage bias and the roles of mobile genetic elements (MGEs) and small interfering RNAs (siRNAs). Interspecific comparisons at the genomic and transcriptomic levels revealed molecular differences, which may contribute to understanding the specialized niches and physiological needs of the respective species. The studies in C. sinensis provide a basis for further basic and applied research in liver flukes and, in particular, the development of efficient means to prevent, diagnose, and treat clonorchiasis.
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Prisoners as Living Donors: A Vulnerabilities Analysis.
Ross, Lainie Friedman; Thistlethwaite, J Richard
2018-01-01
Although national guidelines exist for evaluating the eligibility of potential living donors and for procuring their informed consent, no special protections or considerations exist for potential living donors who are incarcerated. Human research subject protections in the United States are codified in the Federal Regulations, 45 CFR 46, and special protections are given to prisoners. Living donor transplantation has parallels with human subject research in that both activities are performed with the primary goal of benefiting third parties. In this article, we describe what special considerations should be provided to prisoners as potential living donors using a vulnerabilities approach adapted from the human research subject protection literature.
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Benagiano, Giuseppe; d'Arcangues, Catherine; Harris Requejo, Jennifer; Schafer, Alessandra; Say, Lale; Merialdi, Mario
2012-01-01
The Special Programme of Research in Human Reproduction (HRP), co-sponsored by the UNDP, UNFPA, WHO, and the World Bank, is celebrating 40 years of activities with an expansion of its mandate and new co-sponsors. When it began, in 1972, the main focus was on evaluating the acceptability, effectiveness, and safety of existing fertility-regulating methods, as well as developing new, improved modalities for family planning. In 1994, HRP not only made major contributions to the Plan of Action of the International Conference on Population and Development (ICPD); it also broadened its scope of work to include other aspects of health dealing with sexuality and reproduction, adding a specific perspective on gender issues and human rights. In 2002, HRP's mandate was once again broadened to include sexually transmitted infections and HIV/AIDS and in 2003 it was further expanded to research activities on preventing violence against women and its many dire health consequences. Today, the work of the Programme includes research on: the sexual and reproductive health of adolescents, women, and men; maternal and perinatal health; reproductive tract and sexually transmitted infections (including HIV/AIDS); family planning; infertility; unsafe abortion; sexual health; screening for cancer of the cervix in developing countries, and gender and reproductive rights. Additional activities by the Programme have included: fostering international cooperation in the field of human reproduction; the elaboration of WHO's first Global Reproductive Health Strategy; work leading to the inclusion of ICPD's goal 'reproductive health for all by 2015' into the Millennium Development Goal framework; the promotion of critical interagency statements on the public health, legal, and human rights implications of female genital mutilation and gender-biased sex selection. Finally, HRP has been involved in the creation of guidelines and tools, such as the 'Medical eligibility criteria for contraceptive use', the 'Global handbook for family planning providers', the 'Definition of core competencies in primary health care', and designing tools for operationalizing a human rights approach to sexual and reproductive health programmes. Copyright © 2012 S. Karger AG, Basel.
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Manikin Human-Patient Simulator Training.
Horn, Gregory T; Bowling, F Y; Lowe, David E; Parimore, James G; Stagliano, David R; Studer, Nicholas M
Human-patient simulators (HPSs) may help enhance medical education. Manikin HPS devices respond to common field medical interventions, such as cricothyroidotomy, and have realistic feedback features, such as respirations and pulses. This study surveys Special Operations Medics for evaluations of HPS features. Of 518 subjects, 376 completed testing and surveys with valid responses. A total of 102 variables were divided into three categories-general characteristics, procedures, and injuries-and assessed on a fivepoint Likert scale. The Student t test was used to analyze data together and as separate groups against each other and against an aggregated mean. Features that received high scores (i.e., higher than 4.5/5) corresponded closely with pillars of the Tactical Combat Casualty Care (TCCC) curriculum, basic life support, and realism. US Army Special Operations Command and US Special Operations Command Medics have overall high confidence in manikin HPS devices and specifically in those that align with TCCC training and lifesaving procedures. The skills most valued coincide with difficult-to-practice measures, such as cricothyroidotomy and wound packing. Features such as prerecorded sounds, sex, automated movements, skin color, defibrillation, bowel sounds, and electrocardiogram are rated lower. These evaluations may guide future development or procurement of manikin HPS devices. 2017.
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Yakushko, Oksana; Hook, Derek
2017-01-01
This comment addresses the omission of a series of critical reflections in recent discussions of undergraduate education in psychology. The lack of a stronger focus on human meaning and experience, on social context, on methodological diversity, and on social critique limits the critical horizons of undergraduate psychology education. Many perspectives are routinely excluded from undergraduate psychology curricula and associated guidelines, particularly psychoanalytic theories, human science approaches, and related critical standpoints. These perspectives can offer an educational focus vital for development of students capable of critical reflection and social action. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
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Methods in Clinical Pharmacology Series
Beaumont, Claire; Young, Graeme C; Cavalier, Tom; Young, Malcolm A
2014-01-01
Human radiolabel studies are traditionally conducted to provide a definitive understanding of the human absorption, distribution, metabolism and excretion (ADME) properties of a drug. However, advances in technology over the past decade have allowed alternative methods to be employed to obtain both clinical ADME and pharmacokinetic (PK) information. These include microdose and microtracer approaches using accelerator mass spectrometry, and the identification and quantification of metabolites in samples from classical human PK studies using technologies suitable for non-radiolabelled drug molecules, namely liquid chromatography-mass spectrometry and nuclear magnetic resonance spectroscopy. These recently developed approaches are described here together with relevant examples primarily from experiences gained in support of drug development projects at GlaxoSmithKline. The advantages of these study designs together with their limitations are described. We also discuss special considerations which should be made for a successful outcome to these new approaches and also to the more traditional human radiolabel study in order to maximize knowledge around the human ADME properties of drug molecules. PMID:25041729
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Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-10
..., Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Human Immunodeficiency Virus (HIV... evaluation of applications received in response to ``HIV Prevention Projects for Community Based..., Extramural Programs, National Center for HIV, Hepatitis and Sexually Transmitted Diseases Prevention, 1600...
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ERIC Educational Resources Information Center
Beach, Dennis
2011-01-01
The articles in this collection are about the development, possibility, exercise and possible frustration of human agency within educational exchanges. They are also all based on ethnography, which is now a common approach to educational research. Ethnography is not a seamless, neutral observational practice but is instead variable in relation to…
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The Role of Episodic and Semantic Memory in Episodic Foresight
ERIC Educational Resources Information Center
Martin-Ordas, Gema; Atance, Cristina M.; Louw, Alyssa
2012-01-01
In this paper we describe a special form of future thinking, termed "episodic foresight" and its relation with episodic and semantic memory. We outline the methodologies that have largely been developed in the last five years to assess this capacity in young children and non-human animals. Drawing on Tulving's definition of episodic and semantic…
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Vygotskian and Post-Vygotskian Views on Children's Play
ERIC Educational Resources Information Center
Bodrova, Elena; Leong, Deborah J.
2015-01-01
The authors argue that childhood played a special role in the cultural-historical theory of human culture and biosocial development made famous by Soviet psychologist Lev S. Vygotsky and his circle. Th?ey discuss how this school of thought has, in turn, influenced contemporary play studies. Vygotsky used early childhood to test and refi?ne his…
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ERIC Educational Resources Information Center
Abramson, Theodore
Vocational education is a major component of our educational systems at the secondary and postsecondary school level. The passage of the Vocational Education Act of 1963 broadened the definition of vocational education from training people for specific occupations to developing human potential and long-term employability. However, due to the…
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ERIC Educational Resources Information Center
Eres, Figen
2010-01-01
The quality and the prevalence of education are the major indicators of the development of a society. It is a kind of human right to every person living in the society to be educated in a sufficient way. The education of the disabled people, a social reality in Turkey, is not sufficiently carried out. This paper aims at the education of the…
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Eyeblink Conditioning: A Non-Invasive Biomarker for Neurodevelopmental Disorders
ERIC Educational Resources Information Center
Reeb-Sutherland, Bethany C.; Fox, Nathan A.
2015-01-01
Eyeblink conditioning (EBC) is a classical conditioning paradigm typically used to study the underlying neural processes of learning and memory. EBC has a well-defined neural circuitry, is non-invasive, and can be employed in human infants shortly after birth making it an ideal tool to use in both developing and special populations. In addition,…
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Teaching as a Trans-world Activity
ERIC Educational Resources Information Center
Hull, John M.
2004-01-01
John Hull lost his sight more than 20 years ago. He has written extensively about the nature of blindness. In the course of this, he has developed a philosophy of disability or impairment which emphasises the many different worlds of human experience. This leads him to the thought that the teacher of special children, many of whom will be living…
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ERIC Educational Resources Information Center
Texas State Dept. of Human Resources, Austin.
This evaluation report describes programs funded by the Texas Department of Human Resources to develop and implement child abuse and neglect services. Yearly evaluation reports and other related information are included for each of the seven programs funded. In addition to this basic information, the evaluation of the Special Investigative…
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Selective Social Learning: New Perspectives on Learning from Others
ERIC Educational Resources Information Center
Koenig, Melissa A.; Sabbagh, Mark A.
2013-01-01
This special issue was motivated by the recent, wide-ranging interest in the development of children's selective social learning. Human beings have a far-reaching dependence on others for information, and the focus of this issue is on the processes by which children selectively and intelligently learn from others. It showcases some of the finest…
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Chapter II 1985-86 End-of-Year Report. OEA Evaluation Report.
ERIC Educational Resources Information Center
New York City Board of Education, Brooklyn. Office of Educational Assessment.
During the 1985-86 school year the following three New York City high schools received federal funds under Chapter II, Subchapter C, for the development of special programs in the following subjects: (1) A. Philip Randolph--engineering; (2) Townsend Harris--the humanities; and (3) The Paul Robeson School--business and technology. Each of these…
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Christian Voices on World Order. The Whole Earth Papers, Vol. 1, No. 10.
ERIC Educational Resources Information Center
Global Education Associates, East Orange, NJ.
This special issue of the Whole Earth Papers examines Christian perspectives on world order. The document is the first in a series to promote understanding of the ways in which religious and humanist traditions can help develop a more humane world order. Sixteen articles comprise the document. World order issues are explored from various…
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Space Science in Action: Space Exploration [Videotape].
ERIC Educational Resources Information Center
1999
In this videotape recording, students learn about the human quest to discover what is out in space. Students see the challenges and benefits of space exploration including the development of rocket science, a look back at the space race, and a history of manned space travel. A special section on the Saturn V rocket gives students insight into the…
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Protecting the Environment for the Sake of Our Common Future. Special Report 4.
ERIC Educational Resources Information Center
Born, Sigrid, Ed.
In June 1992, representatives of more than 170 countries met in Rio de Janeiro, at the United Nations Conference on Environment and Development, to consider international cooperation aimed at preserving the sources of human life. This report presents Germany's involvement in that cooperative effort. The report is presented in six sections: (1) an…
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In defense of the dignity of being human.
Gaylin, W
1984-08-01
The concept of human dignity is examined in terms of the religious belief that man is created in God's image and from the Kantian viewpoint that man's autonomy gives special value to our species. The theory of psychic determinism and the prospect of genetic engineering of humans are seen as attacks on self determination. Five additional attributes that make humans "special" are explored: conceptual thought, the capacity for technology, our range of emotions, "Lamarckian" environmental genetics, and the freedom to change and modify ourselves.
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Desperately Seeking Special Ed Teachers
ERIC Educational Resources Information Center
Butler, Kevin
2008-01-01
It's no secret that the dearth of special education teachers has created huge headaches for district human resources departments, especially in suburban and rural areas. In addition to insufficient numbers of candidates applying for special education jobs, retention of special education teachers is an ever-greater problem, as research indicates…
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On the Perception of Speech Sounds as Biologically Significant Signals1,2
Pisoni, David B.
2012-01-01
This paper reviews some of the major evidence and arguments currently available to support the view that human speech perception may require the use of specialized neural mechanisms for perceptual analysis. Experiments using synthetically produced speech signals with adults are briefly summarized and extensions of these results to infants and other organisms are reviewed with an emphasis towards detailing those aspects of speech perception that may require some need for specialized species-specific processors. Finally, some comments on the role of early experience in perceptual development are provided as an attempt to identify promising areas of new research in speech perception. PMID:399200
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Johansson, Martin M; Lundin, Elin; Qian, Xiaoyan; Mirzazadeh, Mohammadreza; Halvardson, Jonatan; Darj, Elisabeth; Feuk, Lars; Nilsson, Mats; Jazin, Elena
2016-01-01
Renewed attention has been directed to the functions of the Y chromosome in the central nervous system during early human male development, due to the recent proposed involvement in neurodevelopmental diseases. PCDH11Y and NLGN4Y are of special interest because they belong to gene families involved in cell fate determination and formation of dendrites and axon. We used RNA sequencing, immunocytochemistry and a padlock probing and rolling circle amplification strategy, to distinguish the expression of X and Y homologs in situ in the human brain for the first time. To minimize influence of androgens on the sex differences in the brain, we focused our investigation to human embryos at 8-11 weeks post-gestation. We found that the X- and Y-encoded genes are expressed in specific and heterogeneous cellular sub-populations of both glial and neuronal origins. More importantly, we found differential distribution patterns of X and Y homologs in the male developing central nervous system. This study has visualized the spatial distribution of PCDH11X/Y and NLGN4X/Y in human developing nervous tissue. The observed spatial distribution patterns suggest the existence of an additional layer of complexity in the development of the male CNS.
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American Muslim Undergraduates' Views on Evolution
ERIC Educational Resources Information Center
Fouad, Khadija Engelbrecht
2016-01-01
A qualitative investigation into American Muslim undergraduates' views on evolution revealed three main positions on evolution: theistic evolution, a belief in special creation of all species, and a belief in special creation of humans with evolution for all non-human species. One can conceive of the manner in which respondents chose their…
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Better Thinking and Clearer Communication Will Help Special Education
ERIC Educational Resources Information Center
Kauffman, James M.; Badar, Jeanmarie
2014-01-01
The authors argue that insufficient attention has been given to foundational concepts in special education. Two classes of foundational concepts are discussed: human constructions and logico-mathematical facts. Four human constructions are examined: (1) making teaching most important, (2) discriminating among ideas, (3) choosing conceptual models,…
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Federal Register 2010, 2011, 2012, 2013, 2014
2011-05-11
... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Virologic Evaluation of the Modes of Influenza Virus Transmission Among Humans, Funding Opportunity Announcement, IP11-001 Correction...
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Cognitive Architectures and Human-Computer Interaction. Introduction to Special Issue.
ERIC Educational Resources Information Center
Gray, Wayne D.; Young, Richard M.; Kirschenbaum, Susan S.
1997-01-01
In this introduction to a special issue on cognitive architectures and human-computer interaction (HCI), editors and contributors provide a brief overview of cognitive architectures. The following four architectures represented by articles in this issue are: Soar; LICAI (linked model of comprehension-based action planning and instruction taking);…
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Hemispheric Specialization and the Growth of Human Understanding.
ERIC Educational Resources Information Center
Kinsbourne, Marcel
1982-01-01
Connectionistic notions of hemispheric specialization and use are incompatible with the network organization of the human brain. Although brain organization has correspondence with phenomena at more complex levels of analysis, the correspondence is not categorical in nature, as has been claimed by the left-brain/right-brain theorists. (Author/GC)
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NASA Astrophysics Data System (ADS)
Wakimoto, Atsuko
Change in social circumstances caused by arrival of highly developed information-oriented society has altered what information services in medical libraries should be dramatically. Keeping with complication and diversification of needs by users such as medical doctors, researchers, medical technicians and so on medical librarians have been playing important role in the information activities, and are required to master more specialized knowledge. This paper outlines changes in circumstances surrounding medical libraries, discusses role of medical librarians in online information retrieval services, and introduces various curriculum for library education. The author proposes that humanity of librarian him or herself is still a key factor for library services regardless of advancement of computerization.
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Sensory grammars for sensor networks
Aloimonos, Yiannis
2009-01-01
One of the major goals of Ambient Intelligence and Smart Environments is to interpret human activity sensed by a variety of sensors. In order to develop useful technologies and a subsequent industry around smart environments, we need to proceed in a principled manner. This paper suggests that human activity can be expressed in a language. This is a special language with its own phonemes, its own morphemes (words) and its own syntax and it can be learned using machine learning techniques applied to gargantuan amounts of data collected by sensor networks. Developing such languages will create bridges between Ambient Intelligence and other disciplines. It will also provide a hierarchical structure that can lead to a successful industry. PMID:21897837
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Determination of human body burden baseline date of platinum through autopsy tissue analysis.
Vandiver, F; Duffield, F V; Yoakum, A; Bumgarner, J; Moran, J
1976-01-01
Results of analysis for platinum in 97 autopsy sets are presented. Analysis was performed by a specially developed emission spectrochemical method. Almost half of the individuals studied were found to have detectable platinum in one or more tissue samples. Platinum was found to be deposited in 13 of 21 tissue types investigated. Surprisingly high values were observed in subcutaneous fat, previously not considered to be a target site for platinum deposition. These data will serve as a human tissue platinum burden baseline in EPA's Catalyst Research Program. PMID:1001291
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Neuropsychiatry of creativity.
Mula, Marco; Hermann, Bruce; Trimble, Michael R
2016-04-01
In this paper, we review in brief the development of ideas that over time have tried to explain why some individuals are more creative than others and what may be the neurobiological links underlying artistic creativity. We note associations with another unique human idea, that of genius. In particular, we discuss frontotemporal dementia and bipolar, cyclothymic mood disorder as clinical conditions that are helping to unravel the underlying neuroanatomy and neurochemistry of human creativity. This article is part of a Special Issue entitled "Epilepsy, Art, and Creativity". Copyright © 2016 Elsevier Inc. All rights reserved.
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Early variability in the conceptualisation of "sustainable development and human factors".
Thatcher, Andrew
2012-01-01
The sub-discipline of "sustainable development and human factors" is relatively new, first being used in 2006 with a Technical Committee of the IEA being established only in 2009 and a similar special interest group on "green ergonomics" at the Institute of Ergonomics and Human Factors being established in 2010. In general though, the definitions and practice of "sustainable development" is highly contentious and ambiguous across a range of disciplines. This paper examines the diversity of definitions and approaches to sustainable development and human factors in the early papers in this sub-discipline. An examination of 45 chapters and papers (from 2008 to 2011) reveals a surprising consistency in the definitions used for sustainable development but also a large proportion of the papers where no definitions are given at all. The majority of papers were, however, biased towards an economic capital and social capital emphasis, which is to be expected of work traditionally in the ergonomics paradigm. Further, most papers were theoretical in nature demonstrating a great opportunity for empirical work. The variability in definitions is discussed in relation to the future challenges facing the growth of this emergent sub-discipline and opportunities for further theoretical and empirical work.
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NASA Astrophysics Data System (ADS)
Marks, Stephen
1983-09-01
With the purpose of facilitating the promotion of peace, development, disarmament and human rights education in the context of intense competition for curriculum time, including from other new `educations', some tentative definitions are offered. Clarification of the basic concepts and their implications leads to a discussion of the inter-relationships amongst them. Hence, a conceptual approach is suggested which is based on the Peace — Human Rights — Development dialectic, defended as crucial with regards to education which must go beyond the transmission of knowledge to the involvement of the participants in their own social reality so that they become subjects rather than objects of their own history. Models are developed to illustrate the pedagogical implications of the dialectical relations among the concepts, aimed at (1) enabling coverage of the topics and their inter-relationships in traditional courses, and (2) suggesting themes for specialized courses which would allow more in-depth analysis. Finally, practical issues with examples for secondary-and tertiary-level teaching are discussed. Rather than giving in to some utopian ideal, educators should realistically draw on the ideas currently being worked out in peace, development, disarmament and human rights education.
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Paquette, Natacha; Lassonde, Maryse; Vannasing, Phetsamone; Tremblay, Julie; González-Frankenberger, Berta; Florea, Olivia; Béland, Renée; Lepore, Franco; Gallagher, Anne
2015-02-01
The development of language hemispheric specialization is not well understood in young children, especially regarding expressive language functions. In this study, we investigated age-related changes in expressive language lateralization patterns in a population of children (3-6 and 7-10 years old), adolescents (11-16 years old), and young adults (19-30 years old). During functional near-infrared spectroscopy recordings, all participants performed a verbal fluency task, which consisted in naming as many words as possible belonging to a given semantic category. Hemoglobin concentration changes were measured in bilateral frontal and temporal cortical areas. During the language task, results showed a strong left hemisphere response along with weaker right hemisphere activation in all groups. Age-related increases in hemodynamic responses were found bilaterally, with younger children showing smaller hemodynamic responses than adolescents and adults in both hemispheres. Overall, these findings confirm that a left hemisphere specialization is already established in young children and persists through adulthood. Early left hemisphere specialization for expressive language suggests that language development hinges on structural and functional properties of the human brain with little reorganization occurring with development. Copyright © 2015 Elsevier Ltd. All rights reserved.
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Radiochemistry Research and Training, UC Davis
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sutcliffe, Julie
2012-08-01
The report contains a summary of the accomplishments made during the R2@UCDavis proposal. In brief we proposed to develop new and highly innovative radiotracer methods and to enhance training opportunities to ensure the future availability of human resources for highly specialized fields of radiotracer development chemistry and clinical nuclear medicine research and allied disciplines. The overall scientific objectives of this proposal were to utilize “click” chemistry to facilitate fast and site-specific radiolabeling. Progress was made on all initial goals presented. This funding has to date resulted in publications in high impact journals such as Acta Biomaterialia, Molecular Imaging and Biology,more » Nuclear Medicine and Biology and most recently Environmental Science and technology, and it is anticipated that through the collaborations established during the time course of this funding that future research will be published in clinically relevant journals such as Science Translational Medicine and the Journal of Nuclear Medicine. Trainees involved in this proposal have gone on to further their careers in both academia, industry and the private sector. The collaborative forums established during the time course of this funding will ensure the future availability of human resources for highly specialized fields of radiotracer development chemistry and clinical nuclear medicine research and allied disciplines.« less
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Introduction: Framing 'Post-AIDS' and Global Health Discourses in 2015 and Beyond.
O'Connell, Gráinne
2017-05-19
This special issue, entitled "Post-AIDS' and Global Health Discourses: Interdisciplinary Perspectives,' emerged from a one day Medical Humanities symposium at the Leeds Centre for Medical Humanities, at the University of Leeds, England, on February 27th 2015. This special issue focusses on the perceived deprioritising of HIV and AIDS in the Sustainable Development Goals, or SDGs, that were launched in 2015. The SDGs function as policy benchmarks for all entities within the United Nations system and they supersede the Millennium Development Goals, or MDGs, which expired in 2015. As the word millennium indicates, the MDGs were launched in 2000 and 2015 was designated as the benchmark year when the successes and shortcomings of the MDGs would be critically assessed. One key difference between the MDGs and the SDGs, which D'Ambruoso foregrounds (2013), is that the writing process underpinning the SDGs involved lengthy consultations, and feedback, with communities and health care practitioners around the world. By contrast, because the MDGs were mainly written by government officials, policy makers and health care practitioners without consulting wider communities, the processes underpinning the SDGs consultations are more inclusive than the MDGs. What is most critical about the SDGs for this special issue, however, is that they reflect a clear shift away from 'HIV exceptionalism' and towards what critics have described as 'post-AIDS' rhetoric, specifically when one compares the MDG health goal 6 and the SDG health goal 3.
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Julian, Timothy R; Bustos, Carla; Kwong, Laura H; Badilla, Alejandro D; Lee, Julia; Bischel, Heather N; Canales, Robert A
2018-05-08
Quantitative data on human-environment interactions are needed to fully understand infectious disease transmission processes and conduct accurate risk assessments. Interaction events occur during an individual's movement through, and contact with, the environment, and can be quantified using diverse methodologies. Methods that utilize videography, coupled with specialized software, can provide a permanent record of events, collect detailed interactions in high resolution, be reviewed for accuracy, capture events difficult to observe in real-time, and gather multiple concurrent phenomena. In the accompanying video, the use of specialized software to capture humanenvironment interactions for human exposure and disease transmission is highlighted. Use of videography, combined with specialized software, allows for the collection of accurate quantitative representations of human-environment interactions in high resolution. Two specialized programs include the Virtual Timing Device for the Personal Computer, which collects sequential microlevel activity time series of contact events and interactions, and LiveTrak, which is optimized to facilitate annotation of events in real-time. Opportunities to annotate behaviors at high resolution using these tools are promising, permitting detailed records that can be summarized to gain information on infectious disease transmission and incorporated into more complex models of human exposure and risk.
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Generation of Spinal Motor Neurons from Human Pluripotent Stem Cells.
Santos, David P; Kiskinis, Evangelos
2017-01-01
Human embryonic stem cells (ESCs) are characterized by their unique ability to self-renew indefinitely, as well as to differentiate into any cell type of the human body. Induced pluripotent stem cells (iPSCs) share these salient characteristics with ESCs and can easily be generated from any given individual by reprogramming somatic cell types such as fibroblasts or blood cells. The spinal motor neuron (MN) is a specialized neuronal subtype that synapses with muscle to control movement. Here, we present a method to generate functional, postmitotic, spinal motor neurons through the directed differentiation of ESCs and iPSCs by the use of small molecules. These cells can be utilized to study the development and function of human motor neurons in healthy and disease states.
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The renewal of humanism in psychotherapy: summary and conclusion.
Schneider, Kirk J; Längle, Alfried
2012-12-01
This article summarizes and discusses the main themes to emerge from this special section on the renewal of humanism in psychotherapy. It is concluded that (1) despite some controversies, humanism is both a viable and growing influence among the leading specialty areas of psychotherapy; (2) humanism is a foundational element of effectiveness among these specialty areas; and (3) humanistic training is essential to the development of trainees in the aforementioned specialty areas. The implications of these findings for each of the specialty areas, for the profession of psychotherapy, and for the public at large are elaborated, concluding with a call for a reassessment of priorities in the research, practice, and training of standardized mental health delivery. (c) 2012 APA, all rights reserved.
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An Evaluation of Automotive Interior Packages Based on Human Ocular and Joint Motor Properties
NASA Astrophysics Data System (ADS)
Tanaka, Yoshiyuki; Rakumatsu, Takeshi; Horiue, Masayoshi; Miyazaki, Tooru; Nishikawa, Kazuo; Nouzawa, Takahide; Tsuji, Toshio
This paper proposes a new evaluation method of an automotive interior package based on human oculomotor and joint-motor properties. Assuming the long-term driving situation in the express high way, the three evaluation indices were designed on i) the ratio of head motion at gazing the driving items; ii) the load torque for maintaining the standard driving posture; and iii) the human force manipulability at the end-point of human extremities. Experiments were carried out for two different interior packages with four subjects who have the special knowledge on the automobile development. Evaluation results demonstrate that the proposed method can quantitatively analyze the driving interior in good agreement with the generally accepted subjective opinion in the automobile industry.
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Optimal use of human and machine resources for Space Station assembly operations
NASA Technical Reports Server (NTRS)
Parrish, Joseph C.
1988-01-01
This paper investigates the issues involved in determining the best mix of human and machine resources for assembly of the Space Station. It presents the current Station assembly sequence, along with descriptions of the available assembly resources. A number of methodologies for optimizing the human/machine tradeoff problem have been developed, but the Space Station assembly offers some unique issues that have not yet been addressed. These include a strong constraint on available EVA time for early flights and a phased deployment of assembly resources over time. A methodology for incorporating the previously developed decision methods to the special case of the Space Station is presented. This methodology emphasizes an application of multiple qualitative and quantitative techniques, including simulation and decision analysis, for producing an objective, robust solution to the tradeoff problem.
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Diogo, Rui; Smith, Christopher M; Ziermann, Janine M
2015-11-01
We introduce a new subfield of the recently created field of Evolutionary-Developmental-Anthropology (Evo-Devo-Anth): Evolutionary-Developmental-Pathology-and-Anthropology (Evo-Devo-P'Anth). This subfield combines experimental and developmental studies of nonhuman model organisms, biological anthropology, chordate comparative anatomy and evolution, and the study of normal and pathological human development. Instead of focusing on other organisms to try to better understand human development, evolution, anatomy, and pathology, it places humans as the central case study, i.e., as truly model organism themselves. We summarize the results of our recent Evo-Devo-P'Anth studies and discuss long-standing questions in each of the broader biological fields combined in this subfield, paying special attention to the links between: (1) Human anomalies and variations, nonpentadactyly, homeotic transformations, and "nearest neighbor" vs. "find and seek" muscle-skeleton associations in limb+facial muscles vs. other head muscles; (2) Developmental constraints, the notion of "phylotypic stage," internalism vs. externalism, and the "logic of monsters" vs. "lack of homeostasis" views about human birth defects; (3) Human evolution, reversions, atavisms, paedomorphosis, and peromorphosis; (4) Scala naturae, Haeckelian recapitulation, von Baer's laws, and parallelism between phylogeny and development, here formally defined as "Phylo-Devo parallelism"; and (5) Patau, Edwards, and Down syndrome (trisomies 13, 18, 21), atavisms, apoptosis, heart malformations, and medical implications. © 2015 Wiley Periodicals, Inc.
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Rapid changes in the gut microbiome during human evolution
Moeller, Andrew H.; Li, Yingying; Mpoudi Ngole, Eitel; Ahuka-Mundeke, Steve; Lonsdorf, Elizabeth V.; Pusey, Anne E.; Peeters, Martine; Hahn, Beatrice H.; Ochman, Howard
2014-01-01
Humans are ecosystems containing trillions of microorganisms, but the evolutionary history of this microbiome is obscured by a lack of knowledge about microbiomes of African apes. We sequenced the gut communities of hundreds of chimpanzees, bonobos, and gorillas and developed a phylogenetic approach to reconstruct how present-day human microbiomes have diverged from those of ancestral populations. Compositional change in the microbiome was slow and clock-like during African ape diversification, but human microbiomes have deviated from the ancestral state at an accelerated rate. Relative to the microbiomes of wild apes, human microbiomes have lost ancestral microbial diversity while becoming specialized for animal-based diets. Individual wild apes cultivate more phyla, classes, orders, families, genera, and species of bacteria than do individual humans across a range of societies. These results indicate that humanity has experienced a depletion of the gut flora since diverging from Pan. PMID:25368157
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Rapid changes in the gut microbiome during human evolution.
Moeller, Andrew H; Li, Yingying; Mpoudi Ngole, Eitel; Ahuka-Mundeke, Steve; Lonsdorf, Elizabeth V; Pusey, Anne E; Peeters, Martine; Hahn, Beatrice H; Ochman, Howard
2014-11-18
Humans are ecosystems containing trillions of microorganisms, but the evolutionary history of this microbiome is obscured by a lack of knowledge about microbiomes of African apes. We sequenced the gut communities of hundreds of chimpanzees, bonobos, and gorillas and developed a phylogenetic approach to reconstruct how present-day human microbiomes have diverged from those of ancestral populations. Compositional change in the microbiome was slow and clock-like during African ape diversification, but human microbiomes have deviated from the ancestral state at an accelerated rate. Relative to the microbiomes of wild apes, human microbiomes have lost ancestral microbial diversity while becoming specialized for animal-based diets. Individual wild apes cultivate more phyla, classes, orders, families, genera, and species of bacteria than do individual humans across a range of societies. These results indicate that humanity has experienced a depletion of the gut flora since diverging from Pan.
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A natural history of the human mind: tracing evolutionary changes in brain and cognition
Sherwood, Chet C; Subiaul, Francys; Zawidzki, Tadeusz W
2008-01-01
Since the last common ancestor shared by modern humans, chimpanzees and bonobos, the lineage leading to Homo sapiens has undergone a substantial change in brain size and organization. As a result, modern humans display striking differences from the living apes in the realm of cognition and linguistic expression. In this article, we review the evolutionary changes that occurred in the descent of Homo sapiens by reconstructing the neural and cognitive traits that would have characterized the last common ancestor and comparing these with the modern human condition. The last common ancestor can be reconstructed to have had a brain of approximately 300–400 g that displayed several unique phylogenetic specializations of development, anatomical organization, and biochemical function. These neuroanatomical substrates contributed to the enhancement of behavioral flexibility and social cognition. With this evolutionary history as precursor, the modern human mind may be conceived as a mosaic of traits inherited from a common ancestry with our close relatives, along with the addition of evolutionary specializations within particular domains. These modern human-specific cognitive and linguistic adaptations appear to be correlated with enlargement of the neocortex and related structures. Accompanying this general neocortical expansion, certain higher-order unimodal and multimodal cortical areas have grown disproportionately relative to primary cortical areas. Anatomical and molecular changes have also been identified that might relate to the greater metabolic demand and enhanced synaptic plasticity of modern human brain's. Finally, the unique brain growth trajectory of modern humans has made a significant contribution to our species’ cognitive and linguistic abilities. PMID:18380864
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Next generation human skin constructs as advanced tools for drug development.
Abaci, H E; Guo, Zongyou; Doucet, Yanne; Jacków, Joanna; Christiano, Angela
2017-11-01
Many diseases, as well as side effects of drugs, manifest themselves through skin symptoms. Skin is a complex tissue that hosts various specialized cell types and performs many roles including physical barrier, immune and sensory functions. Therefore, modeling skin in vitro presents technical challenges for tissue engineering. Since the first attempts at engineering human epidermis in 1970s, there has been a growing interest in generating full-thickness skin constructs mimicking physiological functions by incorporating various skin components, such as vasculature and melanocytes for pigmentation. Development of biomimetic in vitro human skin models with these physiological functions provides a new tool for drug discovery, disease modeling, regenerative medicine and basic research for skin biology. This goal, however, has long been delayed by the limited availability of different cell types, the challenges in establishing co-culture conditions, and the ability to recapitulate the 3D anatomy of the skin. Recent breakthroughs in induced pluripotent stem cell (iPSC) technology and microfabrication techniques such as 3D-printing have allowed for building more reliable and complex in vitro skin models for pharmaceutical screening. In this review, we focus on the current developments and prevailing challenges in generating skin constructs with vasculature, skin appendages such as hair follicles, pigmentation, immune response, innervation, and hypodermis. Furthermore, we discuss the promising advances that iPSC technology offers in order to generate in vitro models of genetic skin diseases, such as epidermolysis bullosa and psoriasis. We also discuss how future integration of the next generation human skin constructs onto microfluidic platforms along with other tissues could revolutionize the early stages of drug development by creating reliable evaluation of patient-specific effects of pharmaceutical agents. Impact statement Skin is a complex tissue that hosts various specialized cell types and performs many roles including barrier, immune, and sensory functions. For human-relevant drug testing, there has been a growing interest in building more physiological skin constructs by incorporating different skin components, such as vasculature, appendages, pigment, innervation, and adipose tissue. This paper provides an overview of the strategies to build complex human skin constructs that can faithfully recapitulate human skin and thus can be used in drug development targeting skin diseases. In particular, we discuss recent developments and remaining challenges in incorporating various skin components, availability of iPSC-derived skin cell types and in vitro skin disease models. In addition, we provide insights on the future integration of these complex skin models with other organs on microfluidic platforms as well as potential readout technologies for high-throughput drug screening.
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The tempo of human childhood: a maternal foot on the accelerator, a paternal foot on the brake.
Kotler, Jennifer; Haig, David
2018-03-01
Relative to the life history of other great apes, that of humans is characterized by early weaning and short interbirth intervals (IBIs). We propose that in modern humans, birth until adrenarche, or the rise in adrenal androgens, developmentally corresponds to the period from birth until weaning in great apes and ancestral hominins. According to this hypothesis, humans achieved short IBIs by subdividing ancestral infancy into a nurseling phase, during which offspring fed at the breast, and a weanling phase, during which offspring fed specially prepared foods. Imprinted genes influence the timing of human weaning and adrenarche, with paternally expressed genes promoting delays in childhood maturation and maternally expressed genes promoting accelerated maturation. These observations suggest that the tempo of human development has been shaped by consequences for the fitness of kin, with faster development increasing maternal fitness at a cost to child fitness. The effects of imprinted genes suggest that the duration of the juvenile period (adrenarche until puberty) has also been shaped by evolutionary conflicts within the family. © 2018 The Authors Evolutionary Anthropology Published by Wiley Periodicals, Inc.
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The tempo of human childhood: a maternal foot on the accelerator, a paternal foot on the brake
Haig, David
2018-01-01
Abstract Relative to the life history of other great apes, that of humans is characterized by early weaning and short interbirth intervals (IBIs). We propose that in modern humans, birth until adrenarche, or the rise in adrenal androgens, developmentally corresponds to the period from birth until weaning in great apes and ancestral hominins. According to this hypothesis, humans achieved short IBIs by subdividing ancestral infancy into a nurseling phase, during which offspring fed at the breast, and a weanling phase, during which offspring fed specially prepared foods. Imprinted genes influence the timing of human weaning and adrenarche, with paternally expressed genes promoting delays in childhood maturation and maternally expressed genes promoting accelerated maturation. These observations suggest that the tempo of human development has been shaped by consequences for the fitness of kin, with faster development increasing maternal fitness at a cost to child fitness. The effects of imprinted genes suggest that the duration of the juvenile period (adrenarche until puberty) has also been shaped by evolutionary conflicts within the family. PMID:29575348
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We have got you 'covered': how the meninges control brain development.
Siegenthaler, Julie A; Pleasure, Samuel J
2011-06-01
The meninges have traditionally been viewed as specialized membranes surrounding and protecting the adult brain from injury. However, there is increasing evidence that the fetal meninges play important roles during brain development. Through the release of diffusible factors, the meninges influence the proliferative and migratory behaviors of neural progenitors and neurons in the forebrain and hindbrain. Meningeal cells also secrete and organize the pial basement membrane (BM), a critical anchor point for the radially oriented fibers of neuroepithelial stem cells. With its emerging role in brain development, the potential that defects in meningeal development may underlie certain congenital brain abnormalities in humans should be considered. In this review, we will discuss what is known about assembly of the fetal meninges and review the role of meningeal-derived proteins in mouse and human brain development. Copyright © 2011 Elsevier Ltd. All rights reserved.
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[Human cloning and the protection of women's interests].
Canabes, Marcela Ahumada
2008-01-01
The Human Cloning, both therapeutic and full birth cloning, involves and affects women in a special way. The United Nation's Declaration on the Cloning of Human Beings includes a special clause referred to them. Also the Spanish law does it. This works pretend to analyse the meaning of the inclusion of women's interests in this document. At the same time, I will consider the foundations and the importance of the reference to the women.
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Being Human Beings: The Domains and a Human Realm
2013-03-01
evolutionary step to highlight the human component in conflict. As Francis Bacon said, “It would be an unused fancy and self-contradictory to expect that...Special Operations Command, Special Operations White Paper, 1. 50 Francis Bacon , “The New Organon or True Directions Concerning the Interpretation of...Nature,” 1620, http://www.constitution.org/ bacon /nov_org.htm, (accessed February 24, 2013). 51 Mark E. Redden and Michael P. Hughes, “Global
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Mefford, Melissa A; Zappulla, David C
2016-01-15
Telomerase is a specialized ribonucleoprotein complex that extends the 3' ends of chromosomes to counteract telomere shortening. However, increased telomerase activity is associated with ∼90% of human cancers. The telomerase enzyme minimally requires an RNA (hTR) and a specialized reverse transcriptase protein (TERT) for activity in vitro. Understanding the structure-function relationships within hTR has important implications for human disease. For the first time, we have tested the physical-connectivity requirements in the 451-nucleotide hTR RNA using circular permutations, which reposition the 5' and 3' ends. Our extensive in vitro analysis identified three classes of hTR circular permutants with altered function. First, circularly permuting 3' of the template causes specific defects in repeat-addition processivity, revealing that the template recognition element found in ciliates is conserved in human telomerase RNA. Second, seven circular permutations residing within the catalytically important core and CR4/5 domains completely abolish telomerase activity, unveiling mechanistically critical portions of these domains. Third, several circular permutations between the core and CR4/5 significantly increase telomerase activity. Our extensive circular permutation results provide insights into the architecture and coordination of human telomerase RNA and highlight where the RNA could be targeted for the development of antiaging and anticancer therapeutics. Copyright © 2016, American Society for Microbiology. All Rights Reserved.
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Mefford, Melissa A.
2015-01-01
Telomerase is a specialized ribonucleoprotein complex that extends the 3′ ends of chromosomes to counteract telomere shortening. However, increased telomerase activity is associated with ∼90% of human cancers. The telomerase enzyme minimally requires an RNA (hTR) and a specialized reverse transcriptase protein (TERT) for activity in vitro. Understanding the structure-function relationships within hTR has important implications for human disease. For the first time, we have tested the physical-connectivity requirements in the 451-nucleotide hTR RNA using circular permutations, which reposition the 5′ and 3′ ends. Our extensive in vitro analysis identified three classes of hTR circular permutants with altered function. First, circularly permuting 3′ of the template causes specific defects in repeat-addition processivity, revealing that the template recognition element found in ciliates is conserved in human telomerase RNA. Second, seven circular permutations residing within the catalytically important core and CR4/5 domains completely abolish telomerase activity, unveiling mechanistically critical portions of these domains. Third, several circular permutations between the core and CR4/5 significantly increase telomerase activity. Our extensive circular permutation results provide insights into the architecture and coordination of human telomerase RNA and highlight where the RNA could be targeted for the development of antiaging and anticancer therapeutics. PMID:26503788
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Calzo, Jerel P.; Bogart, Laura M.; Francis, Evelyn; Kornetsky, Susan Z.; Winkler, Sabune J.; Kaberry, Julie M.
2017-01-01
BACKGROUND Engaging community partners as co-investigators in community-based participatory research (CBPR) requires certification in the rules, ethics, and principles governing research. Despite developments in making human research protection trainings more convenient and standardized (e.g., self-paced Internet modules), time constraints and the structure of the content (which may favor academic audiences) may hinder the training of community partners. OBJECTIVES This paper is motivated by a case example in which academic and community partners, and stakeholders of a community-based organization actively engaged the leadership of a pediatric hospital-based Institutional Review Board (IRB) in implementing a brief, community-responsive human subjects training session. METHODS A two hour, discussion-based human subjects training was developed via collaborations between the IRB and the community and academic partners. Interviews with trainees and facilitators after the training were used to evaluate its acceptability and possible future applications. CONCLUSIONS Local Institutional Review Boards have the potential to assist community partners in building sufficient knowledge of human subjects research protections to engage in specific projects, thereby expediting the progress of vital research to address community needs. We propose the need for developing truncated human subjects education materials to train and certify community partners, and creating formally organized entities within academic and medical institutions that specialize in community-based research to guide the development and implementation of alternative human subjects training certification opportunities for community partners. PMID:28230554
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Heimbauer, Lisa A; Beran, Michael J; Owren, Michael J
2011-07-26
A long-standing debate concerns whether humans are specialized for speech perception, which some researchers argue is demonstrated by the ability to understand synthetic speech with significantly reduced acoustic cues to phonetic content. We tested a chimpanzee (Pan troglodytes) that recognizes 128 spoken words, asking whether she could understand such speech. Three experiments presented 48 individual words, with the animal selecting a corresponding visuographic symbol from among four alternatives. Experiment 1 tested spectrally reduced, noise-vocoded (NV) synthesis, originally developed to simulate input received by human cochlear-implant users. Experiment 2 tested "impossibly unspeechlike" sine-wave (SW) synthesis, which reduces speech to just three moving tones. Although receiving only intermittent and noncontingent reward, the chimpanzee performed well above chance level, including when hearing synthetic versions for the first time. Recognition of SW words was least accurate but improved in experiment 3 when natural words in the same session were rewarded. The chimpanzee was more accurate with NV than SW versions, as were 32 human participants hearing these items. The chimpanzee's ability to spontaneously recognize acoustically reduced synthetic words suggests that experience rather than specialization is critical for speech-perception capabilities that some have suggested are uniquely human. Copyright © 2011 Elsevier Ltd. All rights reserved.
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The processing of social stimuli in early infancy: from faces to biological motion perception.
Simion, Francesca; Di Giorgio, Elisa; Leo, Irene; Bardi, Lara
2011-01-01
There are several lines of evidence which suggests that, since birth, the human system detects social agents on the basis of at least two properties: the presence of a face and the way they move. This chapter reviews the infant research on the origin of brain specialization for social stimuli and on the role of innate mechanisms and perceptual experience in shaping the development of the social brain. Two lines of convergent evidence on face detection and biological motion detection will be presented to demonstrate the innate predispositions of the human system to detect social stimuli at birth. As for face detection, experiments will be presented to demonstrate that, by virtue of nonspecific attentional biases, a very coarse template of faces become active at birth. As for biological motion detection, studies will be presented to demonstrate that, since birth, the human system is able to detect social stimuli on the basis of their properties such as the presence of a semi-rigid motion named biological motion. Overall, the empirical evidence converges in supporting the notion that the human system begins life broadly tuned to detect social stimuli and that the progressive specialization will narrow the system for social stimuli as a function of experience. Copyright © 2011 Elsevier B.V. All rights reserved.
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ERIC Educational Resources Information Center
Christodoulou, Joanna A.; Daley, Samantha G.; Katzir, Tami
2009-01-01
The theme of Usable Knowledge in Mind, Brain, and Education will be a special section that will appear regularly in the journal. The section will focus on the synergistic connections between biology, cognitive science, and human development on the one hand and educational thought, policy, and practice on the other. Efforts to create usable…
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ERIC Educational Resources Information Center
National Science Foundation, Arlington, VA. Div. of Science Resources Studies.
This report provides comparisons of U.S. and Japanese science resources and some initial evidence that Japan is expanding the human and financial resources for science while improving the environment for basic research. The data cover science and technology trends in research and development from 1975 to 1994, as well as more recent changes in…
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ERIC Educational Resources Information Center
Boskin, Michael J.
A model of occupational choice based on the theory of human capital is developed and estimated by conditional logit analysis. The empirical results estimated the probability of individuals with certain characteristics (such as race, sex, age, and education) entering each of 11 occupational groups. The results indicate that individuals tend to…
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Transcriptional regulation of podocyte specification and differentiation.
Quaggin, Susan E
2002-05-15
Glomerular visceral epithelial cells (podocytes) are highly specialized cells found in the vertebrate and invertebrate kidney and make up a major portion of the filtration barrier between blood and urinary spaces. During development, specification and differentiation of the podocyte lineage must be tightly orchestrated to produce highly specialized characteristics such as foot processes and slit diaphragms. Furthermore, podocytes are poised to direct incoming endothelial and mesangial cells during glomerular development. They express a number of growth factors that likely play a major role in these processes. Recent findings from transgenic and knockout mouse models and the identification of genes responsible for human podocyte disease have provided insight into transcriptional regulation of some of these processes. These transcription factors include Pax2, WT1 (the Wilms tumor suppressor gene), Pod1 (capsulin, epicardin), Kreisler (maf-1), lmx1b, and mf2. Furthermore, regulatory regions from a podocyte-restricted gene, NPHS1 (nephrin) that are required to direct podocyte-specific expression have been identified from both human and murine genes and provide a tool to further dissect the transcriptional regulation of podocyte-specific gene expression. This article reviews the present state of knowledge regarding transcriptional regulation of podocyte specification and differentiation. Copyright 2002 Wiley-Liss, Inc.
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How long did it last? You would better ask a human
Lacquaniti, Francesco; Carrozzo, Mauro; d’Avella, Andrea; La Scaleia, Barbara; Moscatelli, Alessandro; Zago, Myrka
2014-01-01
In the future, human-like robots will live among people to provide company and help carrying out tasks in cooperation with humans. These interactions require that robots understand not only human actions, but also the way in which we perceive the world. Human perception heavily relies on the time dimension, especially when it comes to processing visual motion. Critically, human time perception for dynamic events is often inaccurate. Robots interacting with humans may want to see the world and tell time the way humans do: if so, they must incorporate human-like fallacy. Observers asked to judge the duration of brief scenes are prone to errors: perceived duration often does not match the physical duration of the event. Several kinds of temporal distortions have been described in the specialized literature. Here we review the topic with a special emphasis on our work dealing with time perception of animate actors versus inanimate actors. This work shows the existence of specialized time bases for different categories of targets. The time base used by the human brain to process visual motion appears to be calibrated against the specific predictions regarding the motion of human figures in case of animate motion, while it can be calibrated against the predictions of motion of passive objects in case of inanimate motion. Human perception of time appears to be strictly linked with the mechanisms used to control movements. Thus, neural time can be entrained by external cues in a similar manner for both perceptual judgments of elapsed time and in motor control tasks. One possible strategy could be to implement in humanoids a unique architecture for dealing with time, which would apply the same specialized mechanisms to both perception and action, similarly to humans. This shared implementation might render the humanoids more acceptable to humans, thus facilitating reciprocal interactions. PMID:24478694
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How long did it last? You would better ask a human.
Lacquaniti, Francesco; Carrozzo, Mauro; d'Avella, Andrea; La Scaleia, Barbara; Moscatelli, Alessandro; Zago, Myrka
2014-01-01
In the future, human-like robots will live among people to provide company and help carrying out tasks in cooperation with humans. These interactions require that robots understand not only human actions, but also the way in which we perceive the world. Human perception heavily relies on the time dimension, especially when it comes to processing visual motion. Critically, human time perception for dynamic events is often inaccurate. Robots interacting with humans may want to see the world and tell time the way humans do: if so, they must incorporate human-like fallacy. Observers asked to judge the duration of brief scenes are prone to errors: perceived duration often does not match the physical duration of the event. Several kinds of temporal distortions have been described in the specialized literature. Here we review the topic with a special emphasis on our work dealing with time perception of animate actors versus inanimate actors. This work shows the existence of specialized time bases for different categories of targets. The time base used by the human brain to process visual motion appears to be calibrated against the specific predictions regarding the motion of human figures in case of animate motion, while it can be calibrated against the predictions of motion of passive objects in case of inanimate motion. Human perception of time appears to be strictly linked with the mechanisms used to control movements. Thus, neural time can be entrained by external cues in a similar manner for both perceptual judgments of elapsed time and in motor control tasks. One possible strategy could be to implement in humanoids a unique architecture for dealing with time, which would apply the same specialized mechanisms to both perception and action, similarly to humans. This shared implementation might render the humanoids more acceptable to humans, thus facilitating reciprocal interactions.
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Chirathivat, Napim; Raja, Sahitya C; Gobes, Sharon M H
2015-06-22
Many aspects of song learning in songbirds resemble characteristics of speech acquisition in humans. Genetic, anatomical and behavioural parallels have most recently been extended with demonstrated similarities in hemispheric dominance between humans and songbirds: the avian higher order auditory cortex is left-lateralized for processing song memories in juvenile zebra finches that already have formed a memory of their fathers' song, just like Wernicke's area in the left hemisphere of the human brain is dominant for speech perception. However, it is unclear if hemispheric specialization is due to pre-existing functional asymmetry or the result of learning itself. Here we show that in juvenile male and female zebra finches that had never heard an adult song before, neuronal activation after initial exposure to a conspecific song is bilateral. Thus, like in humans, hemispheric dominance develops with vocal proficiency. A left-lateralized functional system that develops through auditory-vocal learning may be an evolutionary adaptation that could increase the efficiency of transferring information within one hemisphere, benefiting the production and perception of learned communication signals.
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Chirathivat, Napim; Raja, Sahitya C.; Gobes, Sharon M. H.
2015-01-01
Many aspects of song learning in songbirds resemble characteristics of speech acquisition in humans. Genetic, anatomical and behavioural parallels have most recently been extended with demonstrated similarities in hemispheric dominance between humans and songbirds: the avian higher order auditory cortex is left-lateralized for processing song memories in juvenile zebra finches that already have formed a memory of their fathers’ song, just like Wernicke’s area in the left hemisphere of the human brain is dominant for speech perception. However, it is unclear if hemispheric specialization is due to pre-existing functional asymmetry or the result of learning itself. Here we show that in juvenile male and female zebra finches that had never heard an adult song before, neuronal activation after initial exposure to a conspecific song is bilateral. Thus, like in humans, hemispheric dominance develops with vocal proficiency. A left-lateralized functional system that develops through auditory-vocal learning may be an evolutionary adaptation that could increase the efficiency of transferring information within one hemisphere, benefiting the production and perception of learned communication signals. PMID:26098840
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de Albuquerque, Cleandro Pires
2014-01-01
To assess the distribution of rheumatologists in Brazil and their correlation with Medical Residency specialization offer, Gross Domestic Product (Gdp) And Municipal Human Development Index (HDI-M) of units of the federation (UFs). Query to various official databases, data summarization by techniques for descriptive statistics and cross-referenced information. For correlation analysis, we used the Spearman correlation coefficient (r). There were 1229 rheumatologists regularly registered in the country. The Northern region had only 3.6% of the total (n = 44), while the Southeast had 42.2% (n = 519). The State capitals, added to the five largest municipalities in each UF, concentrated 75.8% of these specialists (n = 931). In total, 49.9% of rheumatologists offered treatment at SUS. A general ratio of 157,809 inhabitants per rheumatologist in Brazil was determined, but with wide variation among UFs with respect to this ratio. In the years 2000-2012, there were 593 Rheumatology Residency graduated physicians in Brazil. We observed a positive correlation among number of rheumatologists compared with GDP (r = 0.94), HDI-M of the State capitals (r = 0.77) and number of Rheumatology Residency graduated physicians (r = 0.79) in UFs. We noted a strong concentration of rheumatologists in State capitals and larger municipalities, with noticeable inequalities also between UFs and country regions. The distribution of these professionals accompanied GDP, HDI-M of the State capital and number of Rheumatology Residency graduated physicians, suggesting that factors related to income opportunities and human development and the place of speciality training may influence the geographical fixation of rheumatologists.
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IgE-based Immunotherapy of Cancer -A Comparative Oncology Approach
Singer, Josef; Jensen-Jarolim, Erika
2014-01-01
Antibody-based immunotherapies are important therapy options in human oncology. Although human humoral specific immunity is constituted of five different immunoglobulin classes, currently only IgG-based immunotherapies have proceeded to clinical application. This review, however, discusses the benefits and difficulties of IgE-based immunotherapy of cancer, with special emphasis on how to translate promising preclinical results into clinical studies. Pursuing the “Comparative Oncology” approach, novel drug candidates are investigated in clinical trials with veterinary cancer patients, most often dogs. By this strategy drug development could be speeded up, animal experiments could be reduced and novel therapy options could be introduced benefitting humans as well as man’s best friend. PMID:25264496
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Music and Early Language Acquisition
Brandt, Anthony; Gebrian, Molly; Slevc, L. Robert
2012-01-01
Language is typically viewed as fundamental to human intelligence. Music, while recognized as a human universal, is often treated as an ancillary ability – one dependent on or derivative of language. In contrast, we argue that it is more productive from a developmental perspective to describe spoken language as a special type of music. A review of existing studies presents a compelling case that musical hearing and ability is essential to language acquisition. In addition, we challenge the prevailing view that music cognition matures more slowly than language and is more difficult; instead, we argue that music learning matches the speed and effort of language acquisition. We conclude that music merits a central place in our understanding of human development. PMID:22973254
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Lee, Chris; Austin, Michael J
2012-01-01
Building on the literature related to evidence-based practice, knowledge management, and learning organizations, this cross-case analysis presents twelve works-in-progress in ten local public human service organizations seeking to develop their own knowledge sharing systems. The data for this cross-case analysis can be found in the various contributions to this Special Issue. The findings feature the developmental aspects of building a learning organization that include knowledge sharing systems featuring transparency, self-assessment, and dissemination and utilization. Implications for practice focus on the structure and processes involved in building knowledge sharing teams inside public human service organizations. Copyright © Taylor & Francis Group, LLC
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Music and early language acquisition.
Brandt, Anthony; Gebrian, Molly; Slevc, L Robert
2012-01-01
Language is typically viewed as fundamental to human intelligence. Music, while recognized as a human universal, is often treated as an ancillary ability - one dependent on or derivative of language. In contrast, we argue that it is more productive from a developmental perspective to describe spoken language as a special type of music. A review of existing studies presents a compelling case that musical hearing and ability is essential to language acquisition. In addition, we challenge the prevailing view that music cognition matures more slowly than language and is more difficult; instead, we argue that music learning matches the speed and effort of language acquisition. We conclude that music merits a central place in our understanding of human development.
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Computer aided systems human engineering: A hypermedia tool
NASA Technical Reports Server (NTRS)
Boff, Kenneth R.; Monk, Donald L.; Cody, William J.
1992-01-01
The Computer Aided Systems Human Engineering (CASHE) system, Version 1.0, is a multimedia ergonomics database on CD-ROM for the Apple Macintosh II computer, being developed for use by human system designers, educators, and researchers. It will initially be available on CD-ROM and will allow users to access ergonomics data and models stored electronically as text, graphics, and audio. The CASHE CD-ROM, Version 1.0 will contain the Boff and Lincoln (1988) Engineering Data Compendium, MIL-STD-1472D and a unique, interactive simulation capability, the Perception and Performance Prototyper. Its features also include a specialized data retrieval, scaling, and analysis capability and the state of the art in information retrieval, browsing, and navigation.
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Discussion on the Development of Green Chemistry and Chemical Engineering
NASA Astrophysics Data System (ADS)
Zhang, Yunshen
2017-11-01
Chemical industry plays a vital role in the development process of national economy. However, in view of the special nature of the chemical industry, a large number of poisonous and harmful substances pose a great threat to the ecological environment and human health in the entire process of raw material acquisition, production, transportation, product manufacturing, and the final practical application. Therefore, it is a general trend to promote the development of chemistry and chemical engineering towards a greener environment. This article will focus on some basic problems occurred in the development process of green chemistry and chemical engineering.
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Meeting Our Responsibilities in Special Education.
ERIC Educational Resources Information Center
LeRoy, C. H.; And Others
1994-01-01
This paper reviews transmission of human immunodeficiency virus and stages of acquired immune deficiency syndrome (AIDS); AIDS symptoms in children; special complications for children with disabilities; and responsibilities of special educators, including, among others, inclusion in schools, interdisciplinary team management, providing a family…
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77 FR 49029 - Excepted Service
Federal Register 2010, 2011, 2012, 2013, 2014
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... the Special DD120075 6/1/2012 Assistant Assistant(Cyber Secretary of Policy). Defense, Global... for Legislation. Department of Homeland Security. Office of the Chief Special Assistant.. DM120131 6/1... Security, Issues. Democracy and Human Rights. Department of Transportation.... Secretary Special Assistant...
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Cabrera, Natasha J; Roggman, Lori
2017-11-01
Both mothers and fathers play with their children, but research on parent-child play interactions is conducted with mothers three times more often than it is with fathers. The articles in this special issue address this gap by focusing on the nature and quality of father-child play, across cultural contexts, and considering whether father play offers something unique and special for early human development, in infancy or early childhood. The studies show that fathers can be just as developmentally supportive as are mothers in terms of being playful and engaged with their children in ways that are related to greater child socioemotional competence, emotion regulation, and vocabulary, and to less aggression, anxiety, and negativity. We encourage future research to examine the cultural influences, family system dynamics, and specificity of timing and types of father-child play in relation to children's developmental competence. © 2017 Michigan Association for Infant Mental Health.
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Site, Sector, Scope: Mapping the Epistemological Landscape of Health Humanities.
Charise, Andrea
2017-12-01
This essay presents a critical appraisal of the current state of baccalaureate Health Humanities, with a special focus on the contextual differences currently influencing the implementation of this field in Canada and, to a lesser extent, the United States and United Kingdom. I argue that the epistemological bedrock of Health Humanities goes beyond that generated by its written texts to include three external factors that are especially pertinent to undergraduate education: site (the setting of Health Humanities education), sector (the disciplinary eligibility for funding) and scope (the critical engagement with a program's local context alongside an emergent "core" of Health Humanities knowledge, learning, and practice). Drawing largely from the Canadian context, I discuss how these differences can inform or obstruct this field's development, and offer preliminary recommendations for encouraging the growth of baccalaureate Health Humanities-in Canada and elsewhere-in light of these factors.
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An adjuvant-modulated vaccine response in human whole blood
Hakimi, Jalil; Azizi, Ali; Ausar, Salvador F.; Todryk, Stephen M.; Rahman, Nausheen; Brookes, Roger H.
2017-01-01
ABSTRACT The restimulation of an immune memory response by in vitro culture of blood cells with a specific antigen has been used as a way to gauge immunity to vaccines for decades. In this commentary we discuss a less appreciated application to support vaccine process development. We report that human whole blood from pre-primed subjects can generate a profound adjuvant-modulated, antigen-specific response to several different vaccine formulations. The response is able to differentiate subtle changes in the quality of an immune memory response to vaccine formulations and can be used to select optimal conditions relating to a particular manufacture process step. While questions relating to closeness to in vivo vaccination remain, the approach is another big step nearer to the more relevant human response. It has special importance for new adjuvant development, complementing other preclinical in vivo and in vitro approaches to considerably de-risk progression of novel vaccines before and throughout early clinical development. Broader implications of the approach are discussed. PMID:28605295
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Avian models with spontaneous autoimmune diseases
Wick, Georg; Andersson, Leif; Hala, Karel; Gershwin, M. Eric; Selmi, Carlo F.; Erf, Gisela F.; Lamont, Susan J.; Sgonc, Roswitha
2012-01-01
Autoimmune diseases in human patients only become clinically manifest when the disease process has developed to a stage where functional compensation by the afflicted organ or system is not possible any more. In order to understand the initial etiologic and pathogenic events that are generally not yet accessible in humans, appropriate animal models are required. In this respect, spontaneously developing models - albeit rare – reflect the situation in humans much more closely than experimentally induced models, including knockout and transgenic mice. The present review describes three spontaneous chicken models for human autoimmune diseases, the Obese strain (OS) with a Hashimoto-like autoimmune thyroiditis, the University of California at Davis lines 200 and 206 (UCD-200 and 206) with a scleroderma-like disease and the amelanotic Smyth line with a vitiligo-like syndrome (SLV). Special emphasis is given to the new opportunities to unravel the genetic basis of these diseases in view of the recently completed sequencing of the chicken genome. PMID:17145302
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77 FR 2545 - Designation of a Class of Employees for Addition to the Special Exposure Cohort
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'What' and 'where' in the human brain.
Ungerleider, L G; Haxby, J V
1994-04-01
Multiple visual areas in the cortex of nonhuman primates are organized into two hierarchically organized and functionally specialized processing pathways, a 'ventral stream' for object vision and a 'dorsal stream' for spatial vision. Recent findings from positron emission tomography activation studies have localized these pathways within the human brain, yielding insights into cortical hierarchies, specialization of function, and attentional mechanisms.
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Stough, Con; Scholey, Andrew; Cropley, Vanessa; Wesnes, Keith; Zangara, Andrea; Pase, Matthew; Savage, Karen; Nolidin, Karen; Lomas, Justine; Downey, Luke
2013-01-01
Bacopa monniera (EBm), an Indian aquatic herb, has been used in traditional Ayurvedic medicine for centuries for indications related to memory and inflammation. More recently specific extracts of EBm have emerged that have been subjected to rigorous in vitro, animal and now human clinical trials. In this paper we discuss some of these studies with special reference to mechanisms and efficacy of a special extract of Bacopa (CDRI08). Studies using this extract indicate that CDRI08 has several modes of action on the human brain. Promising indications for use in humans include improving cognition in the elderly and in patients with neurodegenerative disorders.
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Human Factors in Virtual Reality Development
NASA Technical Reports Server (NTRS)
Kaiser, Mary K.; Proffitt, Dennis R.; Null, Cynthia H. (Technical Monitor)
1995-01-01
This half-day tutorial will provide an overview of basic perceptual functioning as it relates to the design of virtual environment systems. The tutorial consists of three parts. First, basic issues in visual perception will be presented, including discussions of the visual sensations of brightness and color, and the visual perception of depth relationships in three-dimensional space (with a special emphasis on motion -specified depth). The second section will discuss the importance of conducting human-factors user studies and evaluations. Examples and suggestions on how best to get help with user studies will be provided. Finally, we will discuss how, by drawing on their complementary competencies, perceptual psychologists and computer engineers can work as a team to develop optimal VR systems, technologies, and techniques.
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Holistic integrative medicine: toward a new era of medical advancement.
Fan, Daiming
2017-03-01
Medicine has encountered unprecedented problems associated with changes in nature, society, and environment, as well as with new human quests for survival, longevity, and health. In the meantime, the development of medicine is facing challenges that resulted from the over-division and specialization of disciplines and the fragmentation of medical knowledge. To construct a new medical system that is more suitable for human health and disease treatment, holistic integrative medicine (HIM), which regards the human body as a holistic entity, organically integrates the most advanced knowledge and theories in each medical field and the most effective practices in various clinical specialties to revise and adjust on the basis of social, environmental, and psychological conditions. HIM is the inevitable and necessary direction for the future development of medicine. In this article, we illustrated the connotation of HIM, the differences between HIM and other medical conceptions, and the practice of HIM in recent years.
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Specialization in the Human Brain: The Case of Numbers
Kadosh, Roi Cohen; Bahrami, Bahador; Walsh, Vincent; Butterworth, Brian; Popescu, Tudor; Price, Cathy J.
2011-01-01
How numerical representation is encoded in the adult human brain is important for a basic understanding of human brain organization, its typical and atypical development, its evolutionary precursors, cognitive architectures, education, and rehabilitation. Previous studies have shown that numerical processing activates the same intraparietal regions irrespective of the presentation format (e.g., symbolic digits or non-symbolic dot arrays). This has led to claims that there is a single format-independent, numerical representation. In the current study we used a functional magnetic resonance adaptation paradigm, and effective connectivity analysis to re-examine whether numerical processing in the intraparietal sulci is dependent or independent on the format of the stimuli. We obtained two novel results. First, the whole brain analysis revealed that format change (e.g., from dots to digits), in the absence of a change in magnitude, activated the same intraparietal regions as magnitude change, but to a greater degree. Second, using dynamic causal modeling as a tool to disentangle neuronal specialization across regions that are commonly activated, we found that the connectivity between the left and right intraparietal sulci is format-dependent. Together, this line of results supports the idea that numerical representation is subserved by multiple mechanisms within the same parietal regions. PMID:21808615
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78 FR 63207 - Special Emphasis Panel; Meeting
Federal Register 2010, 2011, 2012, 2013, 2014
2013-10-23
... DEPARTMENT OF HEALTH AND HUMAN SERVICES Agency for Healthcare Research and Quality Special Emphasis Panel; Meeting AGENCY: Agency for Healthcare Research and Quality, HHS. ACTION: Notice. SUMMARY...), announcement is made of an Agency for Healthcare Research and Quality (AHRQ) Special Emphasis Panel (SEP...
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NASA Technical Reports Server (NTRS)
Ezer, Neta; Zumbado, Jennifer Rochlis; Sandor, Aniko; Boyer, Jennifer
2011-01-01
Human-robot systems are expected to have a central role in future space exploration missions that extend beyond low-earth orbit [1]. As part of a directed research project funded by NASA s Human Research Program (HRP), researchers at the Johnson Space Center have started to use a variety of techniques, including literature reviews, case studies, knowledge capture, field studies, and experiments to understand critical human-robot interaction (HRI) variables for current and future systems. Activities accomplished to date include observations of the International Space Station s Special Purpose Dexterous Manipulator (SPDM), Robonaut, and Space Exploration Vehicle (SEV), as well as interviews with robotics trainers, robot operators, and developers of gesture interfaces. A survey of methods and metrics used in HRI was completed to identify those most applicable to space robotics. These methods and metrics included techniques and tools associated with task performance, the quantification of human-robot interactions and communication, usability, human workload, and situation awareness. The need for more research in areas such as natural interfaces, compensations for loss of signal and poor video quality, psycho-physiological feedback, and common HRI testbeds were identified. The initial findings from these activities and planned future research are discussed. Human-robot systems are expected to have a central role in future space exploration missions that extend beyond low-earth orbit [1]. As part of a directed research project funded by NASA s Human Research Program (HRP), researchers at the Johnson Space Center have started to use a variety of techniques, including literature reviews, case studies, knowledge capture, field studies, and experiments to understand critical human-robot interaction (HRI) variables for current and future systems. Activities accomplished to date include observations of the International Space Station s Special Purpose Dexterous Manipulator (SPDM), Robonaut, and Space Exploration Vehicle (SEV), as well as interviews with robotics trainers, robot operators, and developers of gesture interfaces. A survey of methods and metrics used in HRI was completed to identify those most applicable to space robotics. These methods and metrics included techniques and tools associated with task performance, the quantification of human-robot interactions and communication, usability, human workload, and situation awareness. The need for more research in areas such as natural interfaces, compensations for loss of signal and poor video quality, psycho-physiological feedback, and common HRI testbeds were identified. The initial findings from these activities and planned future research are discussed.
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Analysis of proposed criteria for human response to vibration
NASA Technical Reports Server (NTRS)
Janeway, R. N.
1975-01-01
The development of criteria for human vibration response is reviewed, including the evolution of the ISO standard 2631. The document is analyzed to show why its application to vehicle ride evaluation is strongly opposed. Alternative vertical horizontal limits for comfort are recommended in the ground vehicle ride frequency range above 1 Hz. These values are derived by correlating the absorbed power findings of Pradko and Lee with other established criteria. Special emphasis is placed on working limits in the frequency range of 1 to 10 Hz since this is the most significant area in ground vehicle ride evaluation.
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Cell biology, biophysics, and mechanobiology: From the basics to Clinics.
Zeng, Y
2017-04-29
Cell biology, biomechanics and biophysics are the key subjects that guide our understanding in diverse areas of tissue growth, development, remodeling and homeostasis. Novel discoveries such as molecular mechanism, and mechanobiological mechanism in cell biology, biomechanics and biophysics play essential roles in our understanding of the pathogenesis of various human diseases, as well as in designing the treatment of these diseases. In addition, studies in these areas will also facilitate early diagnostics of human diseases, such as cardiovascular diseases and cancer. In this special issue, we collected 10 original research articles and 1 review...
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Exclusive inclusion: the violation of human rights and US immigration policy.
Drevdahl, Denise J; Dorcy, Kathleen Shannon
2007-01-01
In this article, we examine US immigration policies relative to those who work as nurses and those who are manual/low-wage laborers. Recruiting foreign nurses from developing countries to alleviate the nursing shortage is a common practice. While specialized visas for these healthcare professionals facilitate the visa application and approval process, immigrants employed in low-wage positions are subjected to long waits for visas, workplace raids, and subsequent deportation. Selective assistance to some immigrants violates basic human rights and global expectations of justice. Moral and ethical frameworks need to guide US immigration policy.
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Telepresence master glove controller for dexterous robotic end-effectors
NASA Technical Reports Server (NTRS)
Fisher, Scott S.
1987-01-01
This paper describes recent research in the Aerospace Human Factors Research Division at NASA's Ames Research Center to develop a glove-like, control and data-recording device (DataGlove) that records and transmits to a host computer in real time, and at appropriate resolution, a numeric data-record of a user's hand/finger shape and dynamics. System configuration and performance specifications are detailed, and current research is discussed investigating its applications in operator control of dexterous robotic end-effectors and for use as a human factors research tool in evaluation of operator hand function requirements and performance in other specialized task environments.
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NASA Technical Reports Server (NTRS)
Drake, Bret G. (Editor)
1998-01-01
This Addendum to the Mars Reference Mission was developed as a companion document to the NASA Special Publication 6107, "Human Exploration of Mars: The Reference Mission of the NASA Mars Exploration Study Team." It summarizes changes and updates to the Mars Reference Missions that were developed by the Exploration Office since the final draft of SP 6107 was printed in early 1999. The Reference Mission is a tool used by the exploration community to compare and evaluate approaches to mission and system concepts that could be used for human missions to Mars. It is intended to identify and clarify system drivers, significant sources of cost, performance, risk, and schedule variation. Several alternative scenarios, employing different technical approaches to solving mission and technology challenges, are discussed in this Addendum. Comparing alternative approaches provides the basis for continual improvement to technology investment plan and a general understanding of future human missions to Mars. The Addendum represents a snapshot of work in progress in support of planning for future human exploration missions through May 1998.
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Löser, Reik; Pietzsch, Jens
2015-01-01
Papain-like cysteine proteases bear an enormous potential as drug discovery targets for both infectious and systemic human diseases. The considerable progress in this field over the last two decades has also raised interest in the visualization of these enzymes in their native context, especially with regard to tumor imaging. After a short introduction to structure and general functions of human cysteine cathepsins, we highlight their importance for drug discovery and development and provide a critical update on the current state of knowledge toward their involvement in tumor progression, with a special emphasis on their role in therapy response. In accordance with a radiopharmaceutical point of view, the main focus of this review article will be the discussion of recently developed fluorescence and radiotracer-based imaging agents together with related molecular probes. PMID:26157794
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Materials and Process Specifications and Standards
1977-11-01
Integrity Requirements; Fracture Control 65 5.9.3 Some Special Problems in Electronic 66 Materials Specifications 5.9.3.1 Thermal Stresses 66...fatigue and fracture and by defining human engineering concepts. Conform to OSHA regulations such as toxicity, noise levels etc. Develop...Standardization Society of the Valves and Fittings Industry. 41 4.6.2.4 OTHER ORGANIZATIONS There are a number of standards-making organizations that cannot
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ERIC Educational Resources Information Center
Johanson, Joyce; Bell, Carol; Daytner, Katrina
2008-01-01
Funded by the U.S. Department of Education's Office of Special Education Programs (OSEP), LitTECH Outreach was a 3-year technology-based preschool literacy project conducted by staff at the Center for Best Practices in Early Childhood, a research and development division of the College of Education and Human Services at Western Illinois…
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ERIC Educational Resources Information Center
Commission of the European Communities, Brussels (Belgium). Directorate-General for Education, Training, and Youth.
The EUROTECNET program has been refocused to concentrate more on continuing vocational education as the area of greatest need across the European Community. Four priority fields or domains of innovative activity have been defined for the final 2 years of EUROTECNET. Priority domain 1 is innovative training needs analysis with a special focus on…
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NASA Technical Reports Server (NTRS)
1975-01-01
Recommendations for using space observations of weather and climate to aid in solving earth based problems are given. Special attention was given to: (1) extending useful forecasting capability of space systems, (2) reducing social, economic, and human losses caused by weather, (3) development of space system capability to manage and control air pollutant concentrations, and (4) establish mechanisms for the national examination of deliberate and inadvertent means for modifying weather and climate.
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ERIC Educational Resources Information Center
Ruiz-Adame Reina, Manuel
2016-01-01
There has been an increase in the aging population in developed countries. This has led to a need for trained people in the gerontological field. The most common academic way of specializing in this field in Spain is via a master's program. It is well known that investing in human capital increases knowledge, productivity, and the probability of…
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Role of Nutrition in Children Growth in View of Traditional Medicine
Farsani, Gholamreza Mohammadi; Movahhed, Mina
2016-01-01
Background: Growth and development are the basic science in pediatric medicine. Growth disorder in children is one of the important health problems in the world, especially in developing countries. Regardless of the underlying disease, as the main cause of growth disorders, assessment and correction of nutritional status of these children are very important. Given the fundamental importance of this issue and ascending tendency to use complementary medicine in the world, this article discusses the traditional Iranian philosopher’s views on the role of nutrition in child development. Methods: This study reviews textbooks of traditional medicine, particularly in the field of pediatric medicine with a focus on Canon of Medicine of Avicenna. Results: Temperament is the physiological concept of the human body in traditional medicine and has an important role in health, diagnosis, and treatment of disease. Generally, children are born with warm and wet temperament that provides the best condition for growth. However, the personal temperament of each child determines growth, the need for a variety of food groups, and even physical activity. Different appetite and food preferences in children show temperamental variation. Therefore, children need special management regarding special temperament. In Iranian traditional medicine, special lifestyle orders are discussed in detail according to these differentiations and nutritional management is the most important factor considered. Conclusion: In spite of advances in classical medicine in the prevention and treatment of many diseases, there are still a lot of therapeutic challenges in many health problems. Temperamental approach to the human body in traditional medicine provides a different perspective on the medicine. Reflecting on temperamental view in child development may lead to a better understanding of the diagnosis and treatment of diseases. On the other hand, further research studies based on the reform of nutrition with respect to temperament should be considered as a new strategy in the management of developmental disorders. PMID:27840523
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Role of Nutrition in Children Growth in View of Traditional Medicine.
Farsani, Gholamreza Mohammadi; Movahhed, Mina
2016-05-01
Growth and development are the basic science in pediatric medicine. Growth disorder in children is one of the important health problems in the world, especially in developing countries. Regardless of the underlying disease, as the main cause of growth disorders, assessment and correction of nutritional status of these children are very important. Given the fundamental importance of this issue and ascending tendency to use complementary medicine in the world, this article discusses the traditional Iranian philosopher's views on the role of nutrition in child development. This study reviews textbooks of traditional medicine, particularly in the field of pediatric medicine with a focus on Canon of Medicine of Avicenna. Temperament is the physiological concept of the human body in traditional medicine and has an important role in health, diagnosis, and treatment of disease. Generally, children are born with warm and wet temperament that provides the best condition for growth. However, the personal temperament of each child determines growth, the need for a variety of food groups, and even physical activity. Different appetite and food preferences in children show temperamental variation. Therefore, children need special management regarding special temperament. In Iranian traditional medicine, special lifestyle orders are discussed in detail according to these differentiations and nutritional management is the most important factor considered. In spite of advances in classical medicine in the prevention and treatment of many diseases, there are still a lot of therapeutic challenges in many health problems. Temperamental approach to the human body in traditional medicine provides a different perspective on the medicine. Reflecting on temperamental view in child development may lead to a better understanding of the diagnosis and treatment of diseases. On the other hand, further research studies based on the reform of nutrition with respect to temperament should be considered as a new strategy in the management of developmental disorders.
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75 FR 61767 - Center For Scientific Review; Notice of Closed Meetings
Federal Register 2010, 2011, 2012, 2013, 2014
2010-10-06
...: Center for Scientific Review Special Emphasis Panel, Special: Signal Transduction and Drug Discovery in... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health Center For Scientific Review... personal privacy. Name of Committee: Center for Scientific Review Special Emphasis Panel, Member Conflict...
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Functional Specialization and Flexibility in Human Association Cortex
Yeo, B. T. Thomas; Krienen, Fenna M.; Eickhoff, Simon B.; Yaakub, Siti N.; Fox, Peter T.; Buckner, Randy L.; Asplund, Christopher L.; Chee, Michael W.L.
2015-01-01
The association cortex supports cognitive functions enabling flexible behavior. Here, we explored the organization of human association cortex by mathematically formalizing the notion that a behavioral task engages multiple cognitive components, which are in turn supported by multiple overlapping brain regions. Application of the model to a large data set of neuroimaging experiments (N = 10 449) identified complex zones of frontal and parietal regions that ranged from being highly specialized to highly flexible. The network organization of the specialized and flexible regions was explored with an independent resting-state fMRI data set (N = 1000). Cortical regions specialized for the same components were strongly coupled, suggesting that components function as partially isolated networks. Functionally flexible regions participated in multiple components to different degrees. This heterogeneous selectivity was predicted by the connectivity between flexible and specialized regions. Functionally flexible regions might support binding or integrating specialized brain networks that, in turn, contribute to the ability to execute multiple and varied tasks. PMID:25249407
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Márquez-Caraveo, Maria Elena; Arroyo-García, Eduardo; Granados-Rojas, Armida; Ángeles-Llerenas, Angélica
2017-01-01
The activities concerning mental health care of psychiatric disorders during more than 50 years of service (1966-2016) at the Children's Psychiatric Hospital "Dr. Juan N. Navarro" (HPI), as well as the progressive development of teaching and research, have contributed to its positioning as a leading institution in medical care of high specialization. This has been possible through the training of human resources that focus the quality of care to the children and their families. The hospital has progressed towards diagnostic and therapeutic care of outpatients through the creation of specialized clinics (emotions, behavior, development, adolescence, among others) and the development of more actualized and integral therapeutic programs (behavioral psychotherapy, cognitive behavioral, psychodynamic; individual, group, family, etc.). In the field of education, the hospital has been the most important institution in the training of child psychiatrists in Mexico and its recognition as a research interdisciplinary center has grown.
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Nature-based solutions for resilient landscapes and cities.
Lafortezza, Raffaele; Chen, Jiquan; van den Bosch, Cecil Konijnendijk; Randrup, Thomas B
2017-12-04
Nature-based solutions (NBS) are increasingly applied to guide the design of resilient landscapes and cities to enable them to reach economic development goals with beneficial outcomes for the environment and society. The NBS concept is closely related to other concepts including sustainability, resilience, ecosystem services, coupled human and environment, and green (blue) infrastructure; however, NBS represent a more efficient and cost-effective approach to development than traditional approaches. The European Commission is actively engaged in investing in NBS as a driver in developing ecosystem services-based approaches throughout Europe and the world. The pool of knowledge and expertise presented in this Special Issue of Environmental Research highlights the applications of NBS as 'living' and adaptable tools to boost the capacity of landscapes and cities to face today's critical environmental, economic and societal challenges. Based on the literature and papers of this Special Issue, we propose five specific challenges for the future of NBS. Copyright © 2017 Elsevier Inc. All rights reserved.
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The Systems Engineering Process for Human Support Technology Development
NASA Technical Reports Server (NTRS)
Jones, Harry
2005-01-01
Systems engineering is designing and optimizing systems. This paper reviews the systems engineering process and indicates how it can be applied in the development of advanced human support systems. Systems engineering develops the performance requirements, subsystem specifications, and detailed designs needed to construct a desired system. Systems design is difficult, requiring both art and science and balancing human and technical considerations. The essential systems engineering activity is trading off and compromising between competing objectives such as performance and cost, schedule and risk. Systems engineering is not a complete independent process. It usually supports a system development project. This review emphasizes the NASA project management process as described in NASA Procedural Requirement (NPR) 7120.5B. The process is a top down phased approach that includes the most fundamental activities of systems engineering - requirements definition, systems analysis, and design. NPR 7120.5B also requires projects to perform the engineering analyses needed to ensure that the system will operate correctly with regard to reliability, safety, risk, cost, and human factors. We review the system development project process, the standard systems engineering design methodology, and some of the specialized systems analysis techniques. We will discuss how they could apply to advanced human support systems development. The purpose of advanced systems development is not directly to supply human space flight hardware, but rather to provide superior candidate systems that will be selected for implementation by future missions. The most direct application of systems engineering is in guiding the development of prototype and flight experiment hardware. However, anticipatory systems engineering of possible future flight systems would be useful in identifying the most promising development projects.
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Application Reuse Library for Software, Requirements, and Guidelines
NASA Technical Reports Server (NTRS)
Malin, Jane T.; Thronesbery, Carroll
1994-01-01
Better designs are needed for expert systems and other operations automation software, for more reliable, usable and effective human support. A prototype computer-aided Application Reuse Library shows feasibility of supporting concurrent development and improvement of advanced software by users, analysts, software developers, and human-computer interaction experts. Such a library expedites development of quality software, by providing working, documented examples, which support understanding, modification and reuse of requirements as well as code. It explicitly documents and implicitly embodies design guidelines, standards and conventions. The Application Reuse Library provides application modules with Demo-and-Tester elements. Developers and users can evaluate applicability of a library module and test modifications, by running it interactively. Sub-modules provide application code and displays and controls. The library supports software modification and reuse, by providing alternative versions of application and display functionality. Information about human support and display requirements is provided, so that modifications will conform to guidelines. The library supports entry of new application modules from developers throughout an organization. Example library modules include a timer, some buttons and special fonts, and a real-time data interface program. The library prototype is implemented in the object-oriented G2 environment for developing real-time expert systems.
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Ecological specialization and rarity indices estimated for a large number of plant species in France
Mobaied, Samira; Machon, Nathalie; Porcher, Emmanuelle
2015-01-01
The biological diversity of the Earth is being rapidly depleted due to the direct and indirect consequences of human activities. Specialist or rare species are generally thought to be more extinction prone than generalist or common species. Testing this assumption however requires that the rarity and ecological specialization of the species are quantified. Many indices have been developed to classify species as generalists vs. specialists or as rare vs. common, but large data sets are needed to calculate these indices. Here, we present a list of specialization and rarity values for more than 2800 plant species of continental France, which were computed from the large botanical and ecological dataset SOPHY. Three specialization indices were calculated using species co-occurrence data. All three indices are based on (dis)similarity among plant communities containing a focal species, quantified either as beta diversity in an additive (Fridley et al., 2007 [6]) or multiplicative (Zeleny, 2008 [15]) partitioning of diversity or as the multiple site similarity of Baselga et al. (2007) [1]. Species rarity was calculated as the inverse of a species occurrence. PMID:26217738
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Specialization and medical mycology in the US, Britain and Japan.
Homei, Aya
2008-03-01
This paper attempts to bring new insights to a long-standing historical debate over medical specialization by analyzing the formation of medical mycology, a somewhat marginal biomedical discipline that emerged in the mid-twentieth century around studies of fungal disease in humans. The study of fungi predates that of bacteria and viruses, but from the 1880s it became eclipsed by bacteriology. However, in the postwar period, there were moves to establish medical mycology as an independent speciality. I trace the processes that led to the launch of professional societies in the United States, Britain and Japan, three major players in medical mycology, and more broadly in biomedicine. The analysis of the three different national contexts illustrates how geographical, medico-technological, epidemiological, political and social conditions gave the specialty a distinctive character in each country; this was further complicated by the different and changing medical fields in which fungal diseases were studied and treated. The three case studies show medical specialization as a process that is not simply cumulative but responds to specific historical events and developments.
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Seth, Ajay; Sherman, Michael; Reinbolt, Jeffrey A; Delp, Scott L
Movement science is driven by observation, but observation alone cannot elucidate principles of human and animal movement. Biomechanical modeling and computer simulation complement observations and inform experimental design. Biological models are complex and specialized software is required for building, validating, and studying them. Furthermore, common access is needed so that investigators can contribute models to a broader community and leverage past work. We are developing OpenSim, a freely available musculoskeletal modeling and simulation application and libraries specialized for these purposes, by providing: musculoskeletal modeling elements, such as biomechanical joints, muscle actuators, ligament forces, compliant contact, and controllers; and tools for fitting generic models to subject-specific data, performing inverse kinematics and forward dynamic simulations. OpenSim performs an array of physics-based analyses to delve into the behavior of musculoskeletal models by employing Simbody, an efficient and accurate multibody system dynamics code. Models are publicly available and are often reused for multiple investigations because they provide a rich set of behaviors that enables different lines of inquiry. This report will discuss one model developed to study walking and applied to gain deeper insights into muscle function in pathological gait and during running. We then illustrate how simulations can test fundamental hypotheses and focus the aims of in vivo experiments, with a postural stability platform and human model that provide a research environment for performing human posture experiments in silico . We encourage wide adoption of OpenSim for community exchange of biomechanical models and methods and welcome new contributors.
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Functional Specialization in the Human Brain Estimated By Intrinsic Hemispheric Interaction
Wang, Danhong; Buckner, Randy L.
2014-01-01
The human brain demonstrates functional specialization, including strong hemispheric asymmetries. Here specialization was explored using fMRI by examining the degree to which brain networks preferentially interact with ipsilateral as opposed to contralateral networks. Preferential within-hemisphere interaction was prominent in the heteromodal association cortices and minimal in the sensorimotor cortices. The frontoparietal control network exhibited strong within-hemisphere interactions but with distinct patterns in each hemisphere. The frontoparietal control network preferentially coupled to the default network and language-related regions in the left hemisphere but to attention networks in the right hemisphere. This arrangement may facilitate control of processing functions that are lateralized. Moreover, the regions most linked to asymmetric specialization also display the highest degree of evolutionary cortical expansion. Functional specialization that emphasizes processing within a hemisphere may allow the expanded hominin brain to minimize between-hemisphere connectivity and distribute domain-specific processing functions. PMID:25209275
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42 CFR 403.815 - Special rules concerning States.
Code of Federal Regulations, 2010 CFR
2010-10-01
... 42 Public Health 2 2010-10-01 2010-10-01 false Special rules concerning States. 403.815 Section 403.815 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN... Transitional Assistance Program § 403.815 Special rules concerning States. (a) Optional State payment of...
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21 CFR 890.3880 - Special grade wheelchair.
Code of Federal Regulations, 2011 CFR
2011-04-01
... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Special grade wheelchair. 890.3880 Section 890.3880 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3880 Special grade...
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21 CFR 890.3880 - Special grade wheelchair.
Code of Federal Regulations, 2012 CFR
2012-04-01
... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Special grade wheelchair. 890.3880 Section 890.3880 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3880 Special grade...
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21 CFR 890.3880 - Special grade wheelchair.
Code of Federal Regulations, 2010 CFR
2010-04-01
... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Special grade wheelchair. 890.3880 Section 890.3880 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3880 Special grade...
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21 CFR 890.3880 - Special grade wheelchair.
Code of Federal Regulations, 2013 CFR
2013-04-01
... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Special grade wheelchair. 890.3880 Section 890.3880 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3880 Special grade...
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21 CFR 890.3880 - Special grade wheelchair.
Code of Federal Regulations, 2014 CFR
2014-04-01
... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Special grade wheelchair. 890.3880 Section 890.3880 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES PHYSICAL MEDICINE DEVICES Physical Medicine Prosthetic Devices § 890.3880 Special grade...