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Sample records for hybrid discrete particle

  1. A reliable light scattering computing for black carbon-containing particles: Hybrid discrete dipole approximation (h-DDA)

    NASA Astrophysics Data System (ADS)

    Moteki, N.

    2015-12-01

    Black carbon (BC) is a light-absorbing carbonaceous aerosol emitted from combustions of fossil fuels and biomasses and is estimated as the second most important contributor to positive climate forcing after the carbon dioxide. In the atmosphere, the fractal aggregate of BC-spherules may be mixed with non-absorbing (or weakly absorbing) compounds that forms morphologically complex "BC-containing particle". A reliable scattering code for BC-containing particles is necessary for predicting mass absorption efficiency of BC and designing/evaluating optical techniques for estimating microphysical properties (i.e., size distribution, mixing state, shape, refractive index) of BC-containing particles. The computational methods that derived from the volume-integral form of the Maxwell equation, such as discrete dipole approximation (DDA), are method of choice for morphologically complex object like BC-containing particles. In ordinary DDA, the entire particle volume is approximated as a collection of tiny cubical dipoles (with side length d) placed on a 3D cubic lattice. For several model BC-containing particles, the comparisons with numerically exact T-matrix method reveals that the ordinary DDA suffered from persistent positive systematic error (up to +30%) in absorption even under d <<λ. The cause of this DDA error is identified to be the shape error in BC-spherules. To eliminate the shape error in BC-spherules, we propose a new DDA methodology which may be called hybrid DDA (h-DDA): each primary BC sphere is assumed as a spherical dipole, while remaining particle volume of coating material is approximated by a collection of tiny cubical dipoles on a 3D cubic lattice. Positive absorption bias up to +30% in ordinary DDA is suppressed to within 3% in h-DDA. In h-DDA code, an efficient FFT-based algorithm for solving the matrix equation has been implemented, by utilizing the multilevel block-Toeplitz property of the submatrix corresponding to inter-dipole interaction within

  2. Discrete Element Modeling of Triboelectrically Charged Particles

    NASA Technical Reports Server (NTRS)

    Hogue, Michael D.; Calle, Carlos I.; Weitzman, Peter S.; Curry, David R.

    2008-01-01

    Tribocharging of particles is common in many processes including fine powder handling and mixing, printer toner transport and dust extraction. In a lunar environment with its high vacuum and lack of water, electrostatic forces are an important factor to consider when designing and operating equipment. Dust mitigation and management is critical to safe and predictable performance of people and equipment. The extreme nature of lunar conditions makes it difficult and costly to carry out experiments on earth which are necessary to better understand how particles gather and transfer charge between each other and with equipment surfaces. DEM (Discrete Element Modeling) provides an excellent virtual laboratory for studying tribocharging of particles as well as for design of devices for dust mitigation and for other purposes related to handling and processing of lunar regolith. Theoretical and experimental work has been performed pursuant to incorporating screened Coulombic electrostatic forces into EDEM, a commercial DEM software package. The DEM software is used to model the trajectories of large numbers of particles for industrial particulate handling and processing applications and can be coupled with other solvers and numerical models to calculate particle interaction with surrounding media and force fields. While simple Coulombic force between two particles is well understood, its operation in an ensemble of particles is more complex. When the tribocharging of particles and surfaces due to frictional contact is also considered, it is necessary to consider longer range of interaction of particles in response to electrostatic charging. The standard DEM algorithm accounts for particle mechanical properties and inertia as a function of particle shape and mass. If fluid drag is neglected, then particle dynamics are governed by contact between particles, between particles and equipment surfaces and gravity forces. Consideration of particle charge and any tribocharging and

  3. Hybrid particles and associated methods

    DOEpatents

    Fox, Robert V; Rodriguez, Rene; Pak, Joshua J; Sun, Chivin

    2015-02-10

    Hybrid particles that comprise a coating surrounding a chalcopyrite material, the coating comprising a metal, a semiconductive material, or a polymer; a core comprising a chalcopyrite material and a shell comprising a functionalized chalcopyrite material, the shell enveloping the core; or a reaction product of a chalcopyrite material and at least one of a reagent, heat, and radiation. Methods of forming the hybrid particles are also disclosed.

  4. Hybrid Discrete-Continuous Markov Decision Processes

    NASA Technical Reports Server (NTRS)

    Feng, Zhengzhu; Dearden, Richard; Meuleau, Nicholas; Washington, Rich

    2003-01-01

    This paper proposes a Markov decision process (MDP) model that features both discrete and continuous state variables. We extend previous work by Boyan and Littman on the mono-dimensional time-dependent MDP to multiple dimensions. We present the principle of lazy discretization, and piecewise constant and linear approximations of the model. Having to deal with several continuous dimensions raises several new problems that require new solutions. In the (piecewise) linear case, we use techniques from partially- observable MDPs (POMDPS) to represent value functions as sets of linear functions attached to different partitions of the state space.

  5. Hybrid discrete/continuum algorithms for stochastic reaction networks

    SciTech Connect

    Safta, Cosmin Sargsyan, Khachik Debusschere, Bert Najm, Habib N.

    2015-01-15

    Direct solutions of the Chemical Master Equation (CME) governing Stochastic Reaction Networks (SRNs) are generally prohibitively expensive due to excessive numbers of possible discrete states in such systems. To enhance computational efficiency we develop a hybrid approach where the evolution of states with low molecule counts is treated with the discrete CME model while that of states with large molecule counts is modeled by the continuum Fokker–Planck equation. The Fokker–Planck equation is discretized using a 2nd order finite volume approach with appropriate treatment of flux components. The numerical construction at the interface between the discrete and continuum regions implements the transfer of probability reaction by reaction according to the stoichiometry of the system. The performance of this novel hybrid approach is explored for a two-species circadian model with computational efficiency gains of about one order of magnitude.

  6. Hybrid discrete/continuum algorithms for stochastic reaction networks

    NASA Astrophysics Data System (ADS)

    Safta, Cosmin; Sargsyan, Khachik; Debusschere, Bert; Najm, Habib N.

    2015-01-01

    Direct solutions of the Chemical Master Equation (CME) governing Stochastic Reaction Networks (SRNs) are generally prohibitively expensive due to excessive numbers of possible discrete states in such systems. To enhance computational efficiency we develop a hybrid approach where the evolution of states with low molecule counts is treated with the discrete CME model while that of states with large molecule counts is modeled by the continuum Fokker-Planck equation. The Fokker-Planck equation is discretized using a 2nd order finite volume approach with appropriate treatment of flux components. The numerical construction at the interface between the discrete and continuum regions implements the transfer of probability reaction by reaction according to the stoichiometry of the system. The performance of this novel hybrid approach is explored for a two-species circadian model with computational efficiency gains of about one order of magnitude.

  7. Hybrid discrete/continuum algorithms for stochastic reaction networks

    SciTech Connect

    Safta, Cosmin; Sargsyan, Khachik; Debusschere, Bert; Najm, Habib N.

    2014-10-22

    Direct solutions of the Chemical Master Equation (CME) governing Stochastic Reaction Networks (SRNs) are generally prohibitively expensive due to excessive numbers of possible discrete states in such systems. To enhance computational efficiency we develop a hybrid approach where the evolution of states with low molecule counts is treated with the discrete CME model while that of states with large molecule counts is modeled by the continuum Fokker-Planck equation. The Fokker-Planck equation is discretized using a 2nd order finite volume approach with appropriate treatment of flux components to avoid negative probability values. The numerical construction at the interface between the discrete and continuum regions implements the transfer of probability reaction by reaction according to the stoichiometry of the system. As a result, the performance of this novel hybrid approach is explored for a two-species circadian model with computational efficiency gains of about one order of magnitude.

  8. Efficient entanglement criteria for discrete, continuous, and hybrid variables

    NASA Astrophysics Data System (ADS)

    Gessner, Manuel; Pezzè, Luca; Smerzi, Augusto

    2016-08-01

    We develop a method to construct entanglement criteria for arbitrary multipartite systems of discrete or continuous variables and hybrid combinations of both. While any set of local operators generates a sufficient condition for entanglement of arbitrary quantum states, a suitable set leads to a necessary and sufficient criterion for pure states. The criteria are readily implementable with existing technology and reveal entanglement that remains undetected by the respective state-of-the-art methods for discrete and continuous variables.

  9. Discrete dipole approximation for black carbon-containing aerosols in arbitrary mixing state: A hybrid discretization scheme

    NASA Astrophysics Data System (ADS)

    Moteki, Nobuhiro

    2016-07-01

    An accurate and efficient simulation of light scattering by an atmospheric black carbon (BC)-containing aerosol-a fractal-like cluster of hundreds of carbon monomers that is internally mixed with other aerosol compounds such as sulfates, organics, and water-remains challenging owing to the enormous diversities of such aerosols' size, shape, and mixing state. Although the discrete dipole approximation (DDA) is theoretically an exact numerical method that is applicable to arbitrary non-spherical inhomogeneous targets, in practice, it suffers from severe granularity-induced error and degradation of computational efficiency for such extremely complex targets. To solve this drawback, we propose herein a hybrid DDA method designed for arbitrary BC-containing aerosols: the monomer-dipole assumption is applied to a cluster of carbon monomers, whereas the efficient cubic-lattice discretization is applied to the remaining particle volume consisting of other materials. The hybrid DDA is free from the error induced by the surface granularity of carbon monomers that occurs in conventional cubic-lattice DDA. In the hybrid DDA, we successfully mitigate the artifact of neglecting the higher-order multipoles in the monomer-dipole assumption by incorporating the magnetic dipole in addition to the electric dipole into our DDA formulations. Our numerical experiments show that the hybrid DDA method is an efficient light-scattering solver for BC-containing aerosols in arbitrary mixing states. The hybrid DDA could be also useful for a cluster of metallic nanospheres associated with other dielectric materials.

  10. Discrete elements method of neutral particle transport

    SciTech Connect

    Mathews, K.A.

    1983-01-01

    A new discrete elements (L/sub N/) transport method is derived and compared to the discrete ordinates S/sub N/ method, theoretically and by numerical experimentation. The discrete elements method is more accurate than discrete ordinates and strongly ameliorates ray effects for the practical problems studied. The discrete elements method is shown to be more cost effective, in terms of execution time with comparable storage to attain the same accuracy, for a one-dimensional test case using linear characteristic spatial quadrature. In a two-dimensional test case, a vacuum duct in a shield, L/sub N/ is more consistently convergent toward a Monte Carlo benchmark solution than S/sub N/, using step characteristic spatial quadrature. An analysis of the interaction of angular and spatial quadrature in xy-geometry indicates the desirability of using linear characteristic spatial quadrature with the L/sub N/ method.

  11. Hybrid discrete/continuum algorithms for stochastic reaction networks

    DOE PAGES

    Safta, Cosmin; Sargsyan, Khachik; Debusschere, Bert; Najm, Habib N.

    2014-10-22

    Direct solutions of the Chemical Master Equation (CME) governing Stochastic Reaction Networks (SRNs) are generally prohibitively expensive due to excessive numbers of possible discrete states in such systems. To enhance computational efficiency we develop a hybrid approach where the evolution of states with low molecule counts is treated with the discrete CME model while that of states with large molecule counts is modeled by the continuum Fokker-Planck equation. The Fokker-Planck equation is discretized using a 2nd order finite volume approach with appropriate treatment of flux components to avoid negative probability values. The numerical construction at the interface between the discretemore » and continuum regions implements the transfer of probability reaction by reaction according to the stoichiometry of the system. As a result, the performance of this novel hybrid approach is explored for a two-species circadian model with computational efficiency gains of about one order of magnitude.« less

  12. FAST TRACK COMMUNICATION: Particle propagators on discrete spacetime

    NASA Astrophysics Data System (ADS)

    Johnston, Steven

    2008-10-01

    A quantum mechanical description of particle propagation on the discrete spacetime of a causal set is presented. The model involves a discrete path integral in which trajectories within the causal set are summed over to obtain a particle propagator. The sum-over-trajectories is achieved by a matrix geometric series. For causal sets generated by sprinkling points into 1+1 and 3+1 dimensional Minkowski spacetime the propagator calculated on the causal set is shown to agree, in a suitable sense, with the causal retarded propagator for the Klein Gordon equation. The particle propagator described here is a step towards quantum field theory on causal set spacetime.

  13. Nanorice Particles: Hybrid Plasmonic Nanostructures

    NASA Technical Reports Server (NTRS)

    Wang, Hui (Inventor); Brandl, Daniel (Inventor); Le, Fei (Inventor); Nordlander, Peter (Inventor); Halas, Nancy J. (Inventor)

    2010-01-01

    A new hybrid nanoparticle, i.e., a nanorice particle, which combines the intense local fields of nanorods with the highly tunable plasmon resonances of nanoshells, is described herein. This geometry possesses far greater structural tunability than previous nanoparticle geometries, along with much larger local field enhancements and far greater sensitivity as a surface plasmon resonance (SPR) nanosensor than presently known dielectric-conductive material nanostructures. In an embodiment, a nanoparticle comprises a prolate spheroid-shaped core having a first aspect ratio. The nanoparticle also comprises at least one conductive shell surrounding said prolate spheroid-shaped core. The nanoparticle has a surface plasmon resonance sensitivity of at least 600 nm RIU(sup.-1). Methods of making the disclosed nanorice particles are also described herein.

  14. Hybrid discrete choice models: Gained insights versus increasing effort.

    PubMed

    Mariel, Petr; Meyerhoff, Jürgen

    2016-10-15

    Hybrid choice models expand the standard models in discrete choice modelling by incorporating psychological factors as latent variables. They could therefore provide further insights into choice processes and underlying taste heterogeneity but the costs of estimating these models often significantly increase. This paper aims at comparing the results from a hybrid choice model and a classical random parameter logit. Point of departure for this analysis is whether researchers and practitioners should add hybrid choice models to their suite of models routinely estimated. Our comparison reveals, in line with the few prior studies, that hybrid models gain in efficiency by the inclusion of additional information. The use of one of the two proposed approaches, however, depends on the objective of the analysis. If disentangling preference heterogeneity is most important, hybrid model seems to be preferable. If the focus is on predictive power, a standard random parameter logit model might be the better choice. Finally, we give recommendations for an adequate use of hybrid choice models based on known principles of elementary scientific inference. PMID:27310534

  15. Hybrid discrete choice models: Gained insights versus increasing effort.

    PubMed

    Mariel, Petr; Meyerhoff, Jürgen

    2016-10-15

    Hybrid choice models expand the standard models in discrete choice modelling by incorporating psychological factors as latent variables. They could therefore provide further insights into choice processes and underlying taste heterogeneity but the costs of estimating these models often significantly increase. This paper aims at comparing the results from a hybrid choice model and a classical random parameter logit. Point of departure for this analysis is whether researchers and practitioners should add hybrid choice models to their suite of models routinely estimated. Our comparison reveals, in line with the few prior studies, that hybrid models gain in efficiency by the inclusion of additional information. The use of one of the two proposed approaches, however, depends on the objective of the analysis. If disentangling preference heterogeneity is most important, hybrid model seems to be preferable. If the focus is on predictive power, a standard random parameter logit model might be the better choice. Finally, we give recommendations for an adequate use of hybrid choice models based on known principles of elementary scientific inference.

  16. Controlling seepage in discrete particle simulations of biological systems.

    PubMed

    Gardiner, Bruce S; Joldes, Grand R; Wong, Kelvin K L; Tan, Chin Wee; Smith, David W

    2016-01-01

    It is now commonplace to represent materials in a simulation using assemblies of discrete particles. Sometimes, one wishes to maintain the integrity of boundaries between particle types, for example, when modelling multiple tissue layers. However, as the particle assembly evolves during a simulation, particles may pass across interfaces. This behaviour is referred to as 'seepage'. The aims of this study were (i) to examine the conditions for seepage through a confining particle membrane and (ii) to define some simple rules that can be employed to control seepage. Based on the force-deformation response of spheres with various sizes and stiffness, we develop analytic expressions for the force required to move a 'probe particle' between confining 'membrane particles'. We analyse the influence that particle's size and stiffness have on the maximum force that can act on the probe particle before the onset of seepage. The theoretical results are applied in the simulation of a biological cell under unconfined compression. PMID:26629728

  17. Nonnegative Anisotropic Group Cross Sections: A Hybrid Monte Carlo-Discrete Elements-Discrete Ordinates Approach

    SciTech Connect

    DelGrande, J. Mark; Mathews, Kirk A.

    2001-09-15

    Conventional discrete ordinates transport calculations often produce negative fluxes due to unphysical negative scattering cross sections and/or as artifacts of spatial differencing schemes such as diamond difference. Inherently nonnegative spatial methods, such as the nonlinear, exponential characteristic spatial quadrature, eliminate negative fluxes while providing excellent accuracy, presuming the group-to-group, ordinate-to-ordinate cross sections are all nonnegative. A hybrid approach is introduced in which the flow from spatial cell to spatial cell uses discrete ordinates spatial quadratures, while anisotropic scattering of flux from one energy-angle bin (energy group and discrete element of solid angle) to another such bin is modeled using a Monte Carlo simulation to evaluate the bin-to-bin cross sections. The directional elements tile the sphere of directions; the ordinates for the spatial quadrature are at the centroids of the elements. The method is developed and contrasted with previous schemes for positive cross sections. An algorithm for evaluating the Monte Carlo (MC)-discrete elements (MC-DE) cross sections is described, and some test cases are presented. Transport calculations using MC-DE cross sections are compared with calculations using conventional cross sections and with MCNP calculations. In this testing, the new method is about as accurate as the conventional approach, and often is more accurate. The exponential characteristic spatial quadrature, using the MC-DE cross sections, is shown to provide useful results where linear characteristic and spherical harmonics provide negative scalar fluxes in every cell in a region.

  18. Discrete mathematical physics and particle modeling

    NASA Astrophysics Data System (ADS)

    Greenspan, D.

    The theory and application of the arithmetic approach to the foundations of both Newtonian and special relativistic mechanics are explored. Using only arithmetic, a reformulation of the Newtonian approach is given for: gravity; particle modeling of solids, liquids, and gases; conservative modeling of laminar and turbulent fluid flow, heat conduction, and elastic vibration; and nonconservative modeling of heat convection, shock-wave generation, the liquid drop problem, porous flow, the interface motion of a melting solid, soap films, string vibrations, and solitons. An arithmetic reformulation of special relativistic mechanics is given for theory in one space dimension, relativistic harmonic oscillation, and theory in three space dimensions. A speculative quantum mechanical model of vibrations in the water molecule is also discussed.

  19. Evolutionary design of discrete controllers for hybrid mechatronic systems

    NASA Astrophysics Data System (ADS)

    Dupuis, Jean-Francois; Fan, Zhun; Goodman, Erik

    2015-01-01

    This paper investigates the issue of evolutionary design of controllers for hybrid mechatronic systems. Finite State Automaton (FSA) is selected as the representation for a discrete controller due to its interpretability, fast execution speed and natural extension to a statechart, which is very popular in industrial applications. A case study of a two-tank system is used to demonstrate that the proposed evolutionary approach can lead to a successful design of an FSA controller for the hybrid mechatronic system, represented by a hybrid bond graph. Generalisation of the evolved FSA controller to unknown control targets is also tested. Further, a comparison with another type of controller, a lookahead controller, is conducted, with advantages and disadvantages of each discussed. The comparison sheds light on which type of controller representation is a better choice to use in various stages of the evolutionary design of controllers for hybrid mechatronic systems. Finally, some important future research directions are pointed out, leading to the major work of the succeeding part of the research.

  20. A local adaptive discretization algorithm for Smoothed Particle Hydrodynamics

    NASA Astrophysics Data System (ADS)

    Spreng, Fabian; Schnabel, Dirk; Mueller, Alexandra; Eberhard, Peter

    2014-06-01

    In this paper, an extension to the Smoothed Particle Hydrodynamics (SPH) method is proposed that allows for an adaptation of the discretization level of a simulated continuum at runtime. By combining a local adaptive refinement technique with a newly developed coarsening algorithm, one is able to improve the accuracy of the simulation results while reducing the required computational cost at the same time. For this purpose, the number of particles is, on the one hand, adaptively increased in critical areas of a simulation model. Typically, these are areas that show a relatively low particle density and high gradients in stress or temperature. On the other hand, the number of SPH particles is decreased for domains with a high particle density and low gradients. Besides a brief introduction to the basic principle of the SPH discretization method, the extensions to the original formulation providing such a local adaptive refinement and coarsening of the modeled structure are presented in this paper. After having introduced its theoretical background, the applicability of the enhanced formulation, as well as the benefit gained from the adaptive model discretization, is demonstrated in the context of four different simulation scenarios focusing on solid continua. While presenting the results found for these examples, several properties of the proposed adaptive technique are discussed, e.g. the conservation of momentum as well as the existing correlation between the chosen refinement and coarsening patterns and the observed quality of the results.

  1. Three dimensional discrete particle simulation of an AOTV

    NASA Technical Reports Server (NTRS)

    Feiereisen, William J.; Mcdonald, Jeffrey D.

    1989-01-01

    A discrete Particle Simulation method, recently formulated by Baganoff, is discussed in the context of its application to the simulation of the flow field about the Aeroassisted Flight Experiment (AFE). As a basis for discussion the current algorithm is first described. Because of the use of a cubic Cartesian mesh, the representation of the geometry is different than that of other particle methods and an algorithm for its generation is discussed. The method is applied to test problems and then to the AFE calculation with the use of 9.52 million particles and 432,000 cells.

  2. Hybrid Automated Diagnosis of Discrete/Continuous Systems

    NASA Technical Reports Server (NTRS)

    Park, Han; James, Mark; MacKey, Ryan; Cannon, Howard; Bajwa, Anapa; Maul, William

    2007-01-01

    A recently conceived method of automated diagnosis of a complex electromechanical system affords a complete set of capabilities for hybrid diagnosis in the case in which the state of the electromechanical system is characterized by both continuous and discrete values (as represented by analog and digital signals, respectively). The method is an integration of two complementary diagnostic systems: (1) beacon-based exception analysis for multi-missions (BEAM), which is primarily useful in the continuous domain and easily performs diagnoses in the presence of transients; and (2) Livingstone, which is primarily useful in the discrete domain and is typically restricted to quasi-steady conditions. BEAM has been described in several prior NASA Tech Briefs articles: "Software for Autonomous Diagnosis of Complex Systems" (NPO-20803), Vol. 26, No. 3 (March 2002), page 33; "Beacon-Based Exception Analysis for Multimissions" (NPO-20827), Vol. 26, No. 9 (September 2002), page 32; "Wavelet-Based Real-Time Diagnosis of Complex Systems" (NPO-20830), Vol. 27, No. 1 (January 2003), page 67; and "Integrated Formulation of Beacon-Based Exception Analysis for Multimissions" (NPO-21126), Vol. 27, No. 3 (March 2003), page 74. Briefly, BEAM is a complete data-analysis method, implemented in software, for real-time or off-line detection and characterization of faults. The basic premise of BEAM is to characterize a system from all available observations and train the characterization with respect to normal phases of operation. The observations are primarily continuous in nature. BEAM isolates anomalies by analyzing the deviations from nominal for each phase of operation. Livingstone is a model-based reasoner that uses a model of a system, controller commands, and sensor observations to track the system s state, and detect and diagnose faults. Livingstone models a system within the discrete domain. Therefore, continuous sensor readings, as well as time, must be discretized. To reason about

  3. Transport and discrete particle noise in gyrokinetic simulations

    NASA Astrophysics Data System (ADS)

    Jenkins, Thomas; Lee, W. W.

    2006-10-01

    We present results from our recent investigations regarding the effects of discrete particle noise on the long-time behavior and transport properties of gyrokinetic particle-in-cell simulations. It is found that the amplitude of nonlinearly saturated drift waves is unaffected by discreteness-induced noise in plasmas whose behavior is dominated by a single mode in the saturated state. We further show that the scaling of this noise amplitude with particle count is correctly predicted by the fluctuation-dissipation theorem, even though the drift waves have driven the plasma from thermal equilibrium. As well, we find that the long-term behavior of the saturated system is unaffected by discreteness-induced noise even when multiple modes are included. Additional work utilizing a code with both total-f and δf capabilities is also presented, as part of our efforts to better understand the long- time balance between entropy production, collisional dissipation, and particle/heat flux in gyrokinetic plasmas.

  4. Computational modeling of brain tumors: discrete, continuum or hybrid?

    NASA Astrophysics Data System (ADS)

    Wang, Zhihui; Deisboeck, Thomas S.

    In spite of all efforts, patients diagnosed with highly malignant brain tumors (gliomas), continue to face a grim prognosis. Achieving significant therapeutic advances will also require a more detailed quantitative understanding of the dynamic interactions among tumor cells, and between these cells and their biological microenvironment. Data-driven computational brain tumor models have the potential to provide experimental tumor biologists with such quantitative and cost-efficient tools to generate and test hypotheses on tumor progression, and to infer fundamental operating principles governing bidirectional signal propagation in multicellular cancer systems. This review highlights the modeling objectives of and challenges with developing such in silico brain tumor models by outlining two distinct computational approaches: discrete and continuum, each with representative examples. Future directions of this integrative computational neuro-oncology field, such as hybrid multiscale multiresolution modeling are discussed.

  5. Determining Trajectory of Triboelectrically Charged Particles, Using Discrete Element Modeling

    NASA Technical Reports Server (NTRS)

    2008-01-01

    The Kennedy Space Center (KSC) Electrostatics and Surface Physics Laboratory is participating in an Innovative Partnership Program (IPP) project with an industry partner to modify a commercial off-the-shelf simulation software product to treat the electrodynamics of particulate systems. Discrete element modeling (DEM) is a numerical technique that can track the dynamics of particle systems. This technique, which was introduced in 1979 for analysis of rock mechanics, was recently refined to include the contact force interaction of particles with arbitrary surfaces and moving machinery. In our work, we endeavor to incorporate electrostatic forces into the DEM calculations to enhance the fidelity of the software and its applicability to (1) particle processes, such as electrophotography, that are greatly affected by electrostatic forces, (2) grain and dust transport, and (3) the study of lunar and Martian regoliths.

  6. Three dimensional Discrete Particle Simulation about the AFE geometry

    NASA Technical Reports Server (NTRS)

    Feiereisen, William J.; Mcdonald, Jeffrey D.; Fallavollita, Michael A.

    1990-01-01

    The Discrete Particle Simulation method, due to Baganoff, has recently been extended to allow representation of gases composed of multiple species, to general power-law molecular interactions and to permit flows in thermal non-equilibrium. Particular attention has been paid to the implementation of this physics while retaining the efficiency of the original algorithm. Here, the enhanced algorithm is applied to the simulation of the flow field about the Aeroassisted Flight Experiment (AFE) vehicle with the same flight parameters as in a previous paper. The enhancements to the algorithm are introduced and comparisons are made to the previous calculation.

  7. Sand Production Modeling Using Superquadric Discrete Elements and Coupling of Fluid Flow and Particle Motion

    SciTech Connect

    Preece, D.S. Perkins, E.D.

    1999-02-10

    Techniques for modeling oil well sand production have been developed using the formulations for superquadric discrete elements and Darcy fluid flow. Discrete element models are generated using the new technique of particle cloning. Discrete element sources and sinks allow simulation of sand production from the initial state through the transition to an equilibrium state where particles are created and removed at the same rate.

  8. Entrainment of coarse grains using a discrete particle model

    SciTech Connect

    Valyrakis, Manousos; Arnold, Roger B. Jr.

    2014-10-06

    Conventional bedload transport models and incipient motion theories relying on a time-averaged boundary shear stress are incapable of accounting for the effects of fluctuating near-bed velocity in turbulent flow and are therefore prone to significant errors. Impulse, the product of an instantaneous force magnitude and its duration, has been recently proposed as an appropriate criterion for quantifying the effects of flow turbulence in removing coarse grains from the bed surface. Here, a discrete particle model (DPM) is used to examine the effects of impulse, representing a single idealized turbulent event, on particle entrainment. The results are classified according to the degree of grain movement into the following categories: motion prior to entrainment, initial dislodgement, and energetic displacement. The results indicate that in all three cases the degree of particle motion depends on both the force magnitude and the duration of its application and suggest that the effects of turbulence must be adequately accounted for in order to develop a more accurate method of determining incipient motion. DPM is capable of simulating the dynamics of grain entrainment and is an appropriate tool for further study of the fundamental mechanisms of sediment transport.

  9. Generation of Random Particle Packings for Discrete Element Models

    NASA Astrophysics Data System (ADS)

    Abe, S.; Weatherley, D.; Ayton, T.

    2012-04-01

    An important step in the setup process of Discrete Element Model (DEM) simulations is the generation of a suitable particle packing. There are quite a number of properties such a granular material specimen should ideally have, such as high coordination number, isotropy, the ability to fill arbitrary bounding volumes and the absence of locked-in stresses. An algorithm which is able to produce specimens fulfilling these requirements is the insertion based sphere packing algorithm originally proposed by Place and Mora, 2001 [2] and extended in this work. The algorithm works in two stages. First a number of "seed" spheres are inserted into the bounding volume. In the second stage the gaps between the "seed" spheres are filled by inserting new spheres in a way so they have D+1 (i.e. 3 in 2D, 4 in 3D) touching contacts with either other spheres or the boundaries of the enclosing volume. Here we present an implementation of the algorithm and a systematic statistical analysis of the generated sphere packings. The analysis of the particle radius distribution shows that they follow a power-law with an exponent ≈ D (i.e. ≈3 for a 3D packing and ≈2 for 2D). Although the algorithm intrinsically guarantees coordination numbers of at least 4 in 3D and 3 in 2D, the coordination numbers realized in the generated packings can be significantly higher, reaching beyond 50 if the range of particle radii is sufficiently large. Even for relatively small ranges of particle sizes (e.g. Rmin = 0.5Rmax) the maximum coordination number may exceed 10. The degree of isotropy of the generated sphere packing is also analysed in both 2D and 3D, by measuring the distribution of orientations of vectors joining the centres of adjacent particles. If the range of particle sizes is small, the packing algorithm yields moderate anisotropy approaching that expected for a face-centred cubic packing of equal-sized particles. However, once Rmin < 0.3Rmax a very high degree of isotropy is demonstrated in

  10. Computer simulations of particle-bubble interactions and particle sliding using Discrete Element Method.

    PubMed

    Maxwell, R; Ata, S; Wanless, E J; Moreno-Atanasio, R

    2012-09-01

    Three dimensional Discrete Element Method (DEM) computer simulations have been carried out to analyse the kinetics of collision of multiple particles against a stationary bubble and the sliding of the particles over the bubble surface. This is the first time that a computational analysis of the sliding time and particle packing arrangements of multiple particles on the surface of a bubble has been carried out. The collision kinetics of monodisperse (33 μm in radius) and polydisperse (12-33 μm in radius) particle systems have been analysed in terms of the time taken by 10%, 50% and 100% of the particles to collide against the bubble. The dependencies of these collision times on the strength of hydrophobic interactions follow relationships close to power laws. However, minimal sensitivity of the collision times to particle size was found when linear and square relationships of the hydrophobic force with particles radius were considered. The sliding time for single particles has corroborated published theoretical expressions. Finally, a good qualitative comparison with experiments has been observed with respect to the particle packing at the bottom of the bubble after sliding demonstrating the usefulness of computer simulations in the studies of particle-bubble systems.

  11. Discrete Particle Noise in Particle-in-Cell Simulations of Plasma Microturbulence

    SciTech Connect

    Nevins, W M; Dimits, A; Hammett, G

    2005-05-24

    Recent gyrokinetic simulations of electron temperature gradient (ETG) turbulence with flux-tube continuum codes vs. the global particle-in-cell (PIC) code GTC yielded different results despite similar plasma parameters. Differences between the simulations results were attributed to insufficient phase-space resolution and novel physics associated with toroidicity and/or global simulations. We have reproduced the results of the global PIC code using the flux-tube PIC code PG3EQ, thereby eliminating global effects as the cause of the discrepancy. We show that the late-time decay of ETG turbulence and the steady-state heat transport observed in these PIC simulations results from discrete particle noise. Discrete particle noise is a numerical artifact, so both these PG3EQ simulations and the previous GTC simulations have nothing to say about steady-state ETG turbulence and the associated anomalous heat transport. In the course of this work we develop three diagnostics which can help to determine if a particular PIC simulation has become dominated by discrete particle noise.

  12. Discrete particle simulations predicting mixing behavior of solid substrate particles in a rotating drum fermenter.

    PubMed

    Schutyser, M A; Padding, J T; Weber, F J; Briels, W J; Rinzema, A; Boom, R

    2001-12-20

    A soft-sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid-state fermentation. In this approach, forces acting on and subsequent motion of individual particles can be predicted. The (2D) simulations were qualitatively and quantitatively validated by mixing experiments using video and image analysis techniques. It was found that the simulations successfully predicted the mixing progress as a function of the degree of filling and size of the drum. It is shown that only relatively large, straight baffles perpendicular to the drum wall (67% of the drum radius) increase the mixing performance of the rotating drum. Considering the different aspects of mixing dealt with in this work, it is concluded that the soft sphere discrete particle model can serve as a valuable tool for investigating mixing of solid substrate particles. Finally, it is expected that this model may evolve into a potential tool for design and scale-up of mixed solid-state fermenters. PMID:11745144

  13. Discrete particle swarm optimization with scout particles for library materials acquisition.

    PubMed

    Wu, Yi-Ling; Ho, Tsu-Feng; Shyu, Shyong Jian; Lin, Bertrand M T

    2013-01-01

    Materials acquisition is one of the critical challenges faced by academic libraries. This paper presents an integer programming model of the studied problem by considering how to select materials in order to maximize the average preference and the budget execution rate under some practical restrictions including departmental budget, limitation of the number of materials in each category and each language. To tackle the constrained problem, we propose a discrete particle swarm optimization (DPSO) with scout particles, where each particle, represented as a binary matrix, corresponds to a candidate solution to the problem. An initialization algorithm and a penalty function are designed to cope with the constraints, and the scout particles are employed to enhance the exploration within the solution space. To demonstrate the effectiveness and efficiency of the proposed DPSO, a series of computational experiments are designed and conducted. The results are statistically analyzed, and it is evinced that the proposed DPSO is an effective approach for the studied problem.

  14. Discrete particle swarm optimization with scout particles for library materials acquisition.

    PubMed

    Wu, Yi-Ling; Ho, Tsu-Feng; Shyu, Shyong Jian; Lin, Bertrand M T

    2013-01-01

    Materials acquisition is one of the critical challenges faced by academic libraries. This paper presents an integer programming model of the studied problem by considering how to select materials in order to maximize the average preference and the budget execution rate under some practical restrictions including departmental budget, limitation of the number of materials in each category and each language. To tackle the constrained problem, we propose a discrete particle swarm optimization (DPSO) with scout particles, where each particle, represented as a binary matrix, corresponds to a candidate solution to the problem. An initialization algorithm and a penalty function are designed to cope with the constraints, and the scout particles are employed to enhance the exploration within the solution space. To demonstrate the effectiveness and efficiency of the proposed DPSO, a series of computational experiments are designed and conducted. The results are statistically analyzed, and it is evinced that the proposed DPSO is an effective approach for the studied problem. PMID:24072983

  15. Discrete elements method of neutral particle transport. Doctoral thesis

    SciTech Connect

    Mathews, K.A.

    1983-10-01

    A new 'discrete elements' (LN) transport method is derived and compared to the discrete ordinates SN method, theoretically and by numerical experimentation. The discrete elements method is more accurate than discrete ordinates and strongly ameliorates ray effects for the practical problems studied. The discrete elements method is shown to be more cost effective in terms of execution time with comparable storage to attain the same accuracy, for a one-dimensional test case using linear characteristic spatial quadrature. In a two-dimensional test case, a vacuum duct in a shield, LN is more consistently convergent toward a Monte Carlo benchmark solution than SN, using step characteristic spatial quadrature. An analysis of the interaction of angular and spatial quadrature in xy-geometry indicates the desirability of using linear characteristic spatial quadrature with the LN method. The discrete elements method is based on discretizing the Boltzmann equation over a set of elements of angle. The zeroth and first angular moments of the directional flux, over each element, are estimated by numerical quadrature and yield a flux-weighted average streaming direction for the element. (Data for this estimation are fluxes in fixed directions calculated as in SN.)

  16. Optical characterization of electrically charged particles using discrete dipole approximation

    NASA Astrophysics Data System (ADS)

    Kocifaj, Miroslav; Kundracik, František; Videen, Gorden

    2016-11-01

    The dependence of the electric potential on the absorption and scattering of light by small particles has emerged as an interesting research topic, as the unexpected amplified optical signatures of a system of electrically charged particles were satisfactory predicted recently for homogeneous, uniformly charged spheres. However, natural particles are rarely of spherical shape. A comprehensive understanding of how arbitrarily shaped, charged particles interact with electromagnetic radiation has been missing. The approach we present here attempts to fill this gap by introducing a numerical formulation of the electromagnetic scattering problem for these particles. The first results from the intercomparison of numerical and analytical solutions for a pseudosphere show that the resonance features found are largely consistent, except for the magnitude and width of the peak amplitude, which may be due to inherent differences in the approaches used.

  17. Discrete Element Modeling (DEM) of Triboelectrically Charged Particles: Revised Experiments

    NASA Technical Reports Server (NTRS)

    Hogue, Michael D.; Calle, Carlos I.; Curry, D. R.; Weitzman, P. S.

    2008-01-01

    In a previous work, the addition of basic screened Coulombic electrostatic forces to an existing commercial discrete element modeling (DEM) software was reported. Triboelectric experiments were performed to charge glass spheres rolling on inclined planes of various materials. Charge generation constants and the Q/m ratios for the test materials were calculated from the experimental data and compared to the simulation output of the DEM software. In this paper, we will discuss new values of the charge generation constants calculated from improved experimental procedures and data. Also, planned work to include dielectrophoretic, Van der Waals forces, and advanced mechanical forces into the software will be discussed.

  18. Investigation of light scattering as a technique for detecting discrete soot particles in a luminous flame

    NASA Technical Reports Server (NTRS)

    1978-01-01

    The practicability of using a classical light-scattering technique, involving comparison of angular scattering intensity patterns with theoretically determined Mie and Rayleight patterns, to detect discrete soot particles (diameter less than 50 nm) in premixed propane/air and propane/oxygen-helium flames is considered. The experimental apparatus employed in this investigation included a laser light source, a flat-flame burner, specially coated optics, a cooled photomultiplier detector, and a lock-in voltmeter readout. Although large, agglomerated soot particles were detected and sized, it was not possible to detect small, discrete particles. The limiting factor appears to be background scattering by the system's optics.

  19. Discrete Abstractions of Hybrid Systems: Verification of Safety and Application to User-Interface Design

    NASA Technical Reports Server (NTRS)

    Oishi, Meeko; Tomlin, Claire; Degani, Asaf

    2003-01-01

    Human interaction with complex hybrid systems involves the user, the automation's discrete mode logic, and the underlying continuous dynamics of the physical system. Often the user-interface of such systems displays a reduced set of information about the entire system. In safety-critical systems, how can we identify user-interface designs which do not have adequate information, or which may confuse the user? Here we describe a methodology, based on hybrid system analysis, to verify that a user-interface contains information necessary to safely complete a desired procedure or task. Verification within a hybrid framework allows us to account for the continuous dynamics underlying the simple, discrete representations displayed to the user. We provide two examples: a car traveling through a yellow light at an intersection and an aircraft autopilot in a landing/go-around maneuver. The examples demonstrate the general nature of this methodology, which is applicable to hybrid systems (not fully automated) which have operational constraints we can pose in terms of safety. This methodology differs from existing work in hybrid system verification in that we directly account for the user's interactions with the system.

  20. Repelling, binding, and oscillating of two-particle discrete-time quantum walks

    NASA Astrophysics Data System (ADS)

    Wang, Qinghao; Li, Zhi-Jian

    2016-10-01

    In this paper, we investigate the effects of particle-particle interaction and static force on the propagation of probability distribution in two-particle discrete-time quantum walk, where the interaction and static force are expressed as a collision phase and a linear position-dependent phase, respectively. It is found that the interaction can lead to boson repelling and fermion binding. The static force also induces Bloch oscillation and results in a continuous transition from boson bunching to fermion anti-bunching. The interplays of particle-particle interaction, quantum interference, and Bloch oscillation provide a versatile framework to study and simulate many-particle physics via quantum walks.

  1. Silicone-containing aqueous polymer dispersions with hybrid particle structure.

    PubMed

    Kozakiewicz, Janusz; Ofat, Izabela; Trzaskowska, Joanna

    2015-09-01

    In this paper the synthesis, characterization and application of silicone-containing aqueous polymer dispersions (APD) with hybrid particle structure are reviewed based on available literature data. Advantages of synthesis of dispersions with hybrid particle structure over blending of individual dispersions are pointed out. Three main processes leading to silicone-containing hybrid APD are identified and described in detail: (1) emulsion polymerization of organic unsaturated monomers in aqueous dispersions of silicone polymers or copolymers, (2) emulsion copolymerization of unsaturated organic monomers with alkoxysilanes or polysiloxanes with unsaturated functionality and (3) emulsion polymerization of alkoxysilanes (in particular with unsaturated functionality) and/or cyclic siloxanes in organic polymer dispersions. The effect of various factors on the properties of such hybrid APD and films as well as on hybrid particles composition and morphology is presented. It is shown that core-shell morphology where silicones constitute either the core or the shell is predominant in hybrid particles. Main applications of silicone-containing hybrid APD and related hybrid particles are reviewed including (1) coatings which show specific surface properties such as enhanced water repellency or antisoiling or antigraffiti properties due to migration of silicone to the surface, and (2) impact modifiers for thermoplastics and thermosets. Other processes in which silicone-containing particles with hybrid structure can be obtained (miniemulsion polymerization, polymerization in non-aqueous media, hybridization of organic polymer and polysiloxane, emulsion polymerization of silicone monomers in silicone polymer dispersions and physical methods) are also discussed. Prospects for further developments in the area of silicone-containing hybrid APD and related hybrid particles are presented.

  2. Fabrication of Discrete Nanosized Cobalt Particles Encapsulated Inside Single-Walled Carbon Nanotubes

    SciTech Connect

    Zoican Loebick, C.; Majewska, M; Ren, F; Haller, G; Pfefferle, L

    2010-01-01

    Single-walled carbon nanotubes (SWNT) with encapsulated nanosized cobalt particles have been synthesized by a facile and scalable method. In this approach, SWNT were filled with a cobalt acetylacetonate solution in dichloromethane by ultrasonication. In a second step, exposure to hydrogen at different temperatures released discrete cobalt particles of controllable size inside the SWNT cavity. The SWNT-Co particles systems were characterized by transmission electron microscopy, X-ray absorption spectroscopy, Raman spectroscopy, and thermal gravimetric analysis.

  3. A hybrid group method of data handling with discrete wavelet transform for GDP forecasting

    NASA Astrophysics Data System (ADS)

    Isa, Nadira Mohamed; Shabri, Ani

    2013-09-01

    This study is proposed the application of hybridization model using Group Method of Data Handling (GMDH) and Discrete Wavelet Transform (DWT) in time series forecasting. The objective of this paper is to examine the flexibility of the hybridization GMDH in time series forecasting by using Gross Domestic Product (GDP). A time series data set is used in this study to demonstrate the effectiveness of the forecasting model. This data are utilized to forecast through an application aimed to handle real life time series. This experiment compares the performances of a hybrid model and a single model of Wavelet-Linear Regression (WR), Artificial Neural Network (ANN), and conventional GMDH. It is shown that the proposed model can provide a promising alternative technique in GDP forecasting.

  4. A hybrid method with deviational particles for spatial inhomogeneous plasma

    NASA Astrophysics Data System (ADS)

    Yan, Bokai

    2016-03-01

    In this work we propose a Hybrid method with Deviational Particles (HDP) for a plasma modeled by the inhomogeneous Vlasov-Poisson-Landau system. We split the distribution into a Maxwellian part evolved by a grid based fluid solver and a deviation part simulated by numerical particles. These particles, named deviational particles, could be both positive and negative. We combine the Monte Carlo method proposed in [31], a Particle in Cell method and a Macro-Micro decomposition method [3] to design an efficient hybrid method. Furthermore, coarse particles are employed to accelerate the simulation. A particle resampling technique on both deviational particles and coarse particles is also investigated and improved. This method is applicable in all regimes and significantly more efficient compared to a PIC-DSMC method near the fluid regime.

  5. Mesoscale dynamic coupling of finite- and discrete-element methods for fluid-particle interactions.

    PubMed

    Srivastava, S; Yazdchi, K; Luding, S

    2014-08-01

    A new method for two-way fluid-particle coupling on an unstructured mesoscopically coarse mesh is presented. In this approach, we combine a (higher order) finite-element method (FEM) on the moving mesh for the fluid with a soft sphere discrete-element method for the particles. The novel feature of the proposed scheme is that the FEM mesh is a dynamic Delaunay triangulation based on the positions of the moving particles. Thus, the mesh can be multi-purpose: it provides (i) a framework for the discretization of the Navier-Stokes equations, (ii) a simple tool for detecting contacts between moving particles, (iii) a basis for coarse-graining or upscaling, and (iv) coupling with other physical fields (temperature, electromagnetic, etc.). This approach is suitable for a wide range of dilute and dense particulate flows, because the mesh resolution adapts with particle density in a given region. Two-way momentum exchange is implemented using semi-empirical drag laws akin to other popular approaches; for example, the discrete particle method, where a finite-volume solver on a coarser, fixed grid is used. We validate the methodology with several basic test cases, including single- and double-particle settling with analytical and empirical expectations, and flow through ordered and random porous media, when compared against finely resolved FEM simulations of flow through fixed arrays of particles. PMID:24982251

  6. Dynamic Equations for a Free Particle Motion in a Discrete Space-Time Geometry

    NASA Astrophysics Data System (ADS)

    Rylov, Yuri A.

    2016-08-01

    One considers the discrete space-time geometry Gd, which is given on the set of points (events), where the geometry of Minkowski is given. This discrete geometry is not a geometry on lattice. Motion of a free particle is considered in Gd. Free motion in Gd can be reduced to a motion in geometry of Minkowski GM in some force field. Primordial free motion in Gd appears to be stochastic. In GM it is difficult to describe the force field responsible for stochastic motion of a particle. The nature of this force field appears to be geometrical.

  7. Ionospheric convection associated with discrete levels of particle precipitation

    SciTech Connect

    Foster, J.C.; Holt, J.M.; Musgrove, R.G.; Evans, D.S.

    1986-07-01

    A precipitation index is described which quantifies the intensity and spatial extent of high-latitude particle precipitation based on observations made along individual satellite passes. By sorting plasma-convection data according to this index, average patterns of the ionospheric convection electric field were derived from a data set consisting of five years' observations by the Millstone Hill radar. Reference to the instantaneous precipitation index, and the average patterns keyed to it, provides a means of characterizing the global precipitation and convection patterns throughout an event.

  8. Development of a coupled discrete element (DEM)-smoothed particle hydrodynamics (SPH) simulation method for polyhedral particles

    NASA Astrophysics Data System (ADS)

    Nassauer, Benjamin; Liedke, Thomas; Kuna, Meinhard

    2016-03-01

    In the present paper, the direct coupling of a discrete element method (DEM) with polyhedral particles and smoothed particle hydrodynamics (SPH) is presented. The two simulation techniques are fully coupled in both ways through interaction forces between the solid DEM particles and the fluid SPH particles. Thus this simulation method provides the possibility to simulate the individual movement of polyhedral, sharp-edged particles as well as the flow field around these particles in fluid-saturated granular matter which occurs in many technical processes e.g. wire sawing, grinding or lapping. The coupled method is exemplified and validated by the simulation of a particle in a shear flow, which shows good agreement with analytical solutions.

  9. Preliminary discrete element modeling of a falling particle curtain for CSP central tower receivers

    NASA Astrophysics Data System (ADS)

    Zanino, R.; Ho, C. K.; Romano, D.; Savoldi, L.

    2016-05-01

    Current methods used to simulate the curtain thickness in a falling particle receiver lead to a poor agreement with the experiments. Here the Discrete Element Method (DEM) is proposed to address the problem, including both the top hopper and the interactions between particles in the model. Some first promising results are presented, showing an acceptable agreement between simulation and experiment for an ad-hoc set of input parameters. A sensitivity study provides a first assessment of the effects of the main input parameters of the model (boundary conditions at the release, particle Young's modulus, restitution coefficients and effective particle diameter) on the predicted curtain thickness.

  10. Coupled Hybrid Continuum-Discrete Model of Tumor Angiogenesis and Growth

    PubMed Central

    Lyu, Jie; Cao, Jinfeng; Zhang, Peiming; Liu, Yang; Cheng, Hongtao

    2016-01-01

    The processes governing tumor growth and angiogenesis are codependent. To study the relationship between them, we proposed a coupled hybrid continuum-discrete model. In this model, tumor cells, their microenvironment (extracellular matrixes, matrix-degrading enzymes, and tumor angiogenic factors), and their network of blood vessels, described by a series of discrete points, were considered. The results of numerical simulation reveal the process of tumor growth and the change in microenvironment from avascular to vascular stage, indicating that the network of blood vessels develops gradually as the tumor grows. Our findings also reveal that a tumor is divided into three regions: necrotic, semi-necrotic, and well-vascularized. The results agree well with the previous relevant studies and physiological facts, and this model represents a platform for further investigations of tumor therapy. PMID:27701426

  11. Particle models for discrete element modeling of bulk grain properties of wheat kernels

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Recent research has shown the potential of discrete element method (DEM) in simulating grain flow in bulk handling systems. Research has also revealed that simulation of grain flow with DEM requires establishment of appropriate particle models for each grain type. This research completes the three-p...

  12. Combining Particle Filters and Consistency-Based Approaches for Monitoring and Diagnosis of Stochastic Hybrid Systems

    NASA Technical Reports Server (NTRS)

    Narasimhan, Sriram; Dearden, Richard; Benazera, Emmanuel

    2004-01-01

    Fault detection and isolation are critical tasks to ensure correct operation of systems. When we consider stochastic hybrid systems, diagnosis algorithms need to track both the discrete mode and the continuous state of the system in the presence of noise. Deterministic techniques like Livingstone cannot deal with the stochasticity in the system and models. Conversely Bayesian belief update techniques such as particle filters may require many computational resources to get a good approximation of the true belief state. In this paper we propose a fault detection and isolation architecture for stochastic hybrid systems that combines look-ahead Rao-Blackwellized Particle Filters (RBPF) with the Livingstone 3 (L3) diagnosis engine. In this approach RBPF is used to track the nominal behavior, a novel n-step prediction scheme is used for fault detection and L3 is used to generate a set of candidates that are consistent with the discrepant observations which then continue to be tracked by the RBPF scheme.

  13. The Discrete Multi-Hybrid System for the Simulation of Solid-Liquid Flows

    PubMed Central

    Alexiadis, Alessio

    2015-01-01

    This study proposes a model based on the combination of Smoothed Particle Hydrodynamics, Coarse Grained Molecular Dynamics and the Discrete Element Method for the simulation of dispersed solid-liquid flows. The model can deal with a large variety of particle types (non-spherical, elastic, breakable, melting, solidifying, swelling), flow conditions (confined, free-surface, microscopic), and scales (from microns to meters). Various examples, ranging from biological fluids to lava flows, are simulated and discussed. In all cases, the model captures the most important features of the flow. PMID:25961561

  14. Discrete Particle Swarm Optimization Routing Protocol for Wireless Sensor Networks with Multiple Mobile Sinks.

    PubMed

    Yang, Jin; Liu, Fagui; Cao, Jianneng; Wang, Liangming

    2016-01-01

    Mobile sinks can achieve load-balancing and energy-consumption balancing across the wireless sensor networks (WSNs). However, the frequent change of the paths between source nodes and the sinks caused by sink mobility introduces significant overhead in terms of energy and packet delays. To enhance network performance of WSNs with mobile sinks (MWSNs), we present an efficient routing strategy, which is formulated as an optimization problem and employs the particle swarm optimization algorithm (PSO) to build the optimal routing paths. However, the conventional PSO is insufficient to solve discrete routing optimization problems. Therefore, a novel greedy discrete particle swarm optimization with memory (GMDPSO) is put forward to address this problem. In the GMDPSO, particle's position and velocity of traditional PSO are redefined under discrete MWSNs scenario. Particle updating rule is also reconsidered based on the subnetwork topology of MWSNs. Besides, by improving the greedy forwarding routing, a greedy search strategy is designed to drive particles to find a better position quickly. Furthermore, searching history is memorized to accelerate convergence. Simulation results demonstrate that our new protocol significantly improves the robustness and adapts to rapid topological changes with multiple mobile sinks, while efficiently reducing the communication overhead and the energy consumption. PMID:27428971

  15. Discrete Particle Swarm Optimization Routing Protocol for Wireless Sensor Networks with Multiple Mobile Sinks.

    PubMed

    Yang, Jin; Liu, Fagui; Cao, Jianneng; Wang, Liangming

    2016-01-01

    Mobile sinks can achieve load-balancing and energy-consumption balancing across the wireless sensor networks (WSNs). However, the frequent change of the paths between source nodes and the sinks caused by sink mobility introduces significant overhead in terms of energy and packet delays. To enhance network performance of WSNs with mobile sinks (MWSNs), we present an efficient routing strategy, which is formulated as an optimization problem and employs the particle swarm optimization algorithm (PSO) to build the optimal routing paths. However, the conventional PSO is insufficient to solve discrete routing optimization problems. Therefore, a novel greedy discrete particle swarm optimization with memory (GMDPSO) is put forward to address this problem. In the GMDPSO, particle's position and velocity of traditional PSO are redefined under discrete MWSNs scenario. Particle updating rule is also reconsidered based on the subnetwork topology of MWSNs. Besides, by improving the greedy forwarding routing, a greedy search strategy is designed to drive particles to find a better position quickly. Furthermore, searching history is memorized to accelerate convergence. Simulation results demonstrate that our new protocol significantly improves the robustness and adapts to rapid topological changes with multiple mobile sinks, while efficiently reducing the communication overhead and the energy consumption.

  16. Discrete particle swarm optimization for identifying community structures in signed social networks.

    PubMed

    Cai, Qing; Gong, Maoguo; Shen, Bo; Ma, Lijia; Jiao, Licheng

    2014-10-01

    Modern science of networks has facilitated us with enormous convenience to the understanding of complex systems. Community structure is believed to be one of the notable features of complex networks representing real complicated systems. Very often, uncovering community structures in networks can be regarded as an optimization problem, thus, many evolutionary algorithms based approaches have been put forward. Particle swarm optimization (PSO) is an artificial intelligent algorithm originated from social behavior such as birds flocking and fish schooling. PSO has been proved to be an effective optimization technique. However, PSO was originally designed for continuous optimization which confounds its applications to discrete contexts. In this paper, a novel discrete PSO algorithm is suggested for identifying community structures in signed networks. In the suggested method, particles' status has been redesigned in discrete form so as to make PSO proper for discrete scenarios, and particles' updating rules have been reformulated by making use of the topology of the signed network. Extensive experiments compared with three state-of-the-art approaches on both synthetic and real-world signed networks demonstrate that the proposed method is effective and promising. PMID:24856248

  17. A Review of Discrete Element Method (DEM) Particle Shapes and Size Distributions for Lunar Soil

    NASA Technical Reports Server (NTRS)

    Lane, John E.; Metzger, Philip T.; Wilkinson, R. Allen

    2010-01-01

    As part of ongoing efforts to develop models of lunar soil mechanics, this report reviews two topics that are important to discrete element method (DEM) modeling the behavior of soils (such as lunar soils): (1) methods of modeling particle shapes and (2) analytical representations of particle size distribution. The choice of particle shape complexity is driven primarily by opposing tradeoffs with total number of particles, computer memory, and total simulation computer processing time. The choice is also dependent on available DEM software capabilities. For example, PFC2D/PFC3D and EDEM support clustering of spheres; MIMES incorporates superquadric particle shapes; and BLOKS3D provides polyhedra shapes. Most commercial and custom DEM software supports some type of complex particle shape beyond the standard sphere. Convex polyhedra, clusters of spheres and single parametric particle shapes such as the ellipsoid, polyellipsoid, and superquadric, are all motivated by the desire to introduce asymmetry into the particle shape, as well as edges and corners, in order to better simulate actual granular particle shapes and behavior. An empirical particle size distribution (PSD) formula is shown to fit desert sand data from Bagnold. Particle size data of JSC-1a obtained from a fine particle analyzer at the NASA Kennedy Space Center is also fitted to a similar empirical PSD function.

  18. Continuous and Discrete Space Particle Filters for Predictions in Acoustic Positioning

    NASA Astrophysics Data System (ADS)

    Bauer, Will; Kim, Surrey; Kouritzin, Michael A.

    2002-12-01

    Predicting the future state of a random dynamic signal based on corrupted, distorted, and partial observations is vital for proper real-time control of a system that includes time delay. Motivated by problems from Acoustic Positioning Research Inc., we consider the continual automated illumination of an object moving within a bounded domain, which requires object location prediction due to inherent mechanical and physical time lags associated with robotic lighting. Quality computational predictions demand high fidelity models for the coupled moving object signal and observation equipment pair. In our current problem, the signal represents the vector position, orientation, and velocity of a stage performer. Acoustic observations are formed by timing ultrasonic waves traveling from four perimeter speakers to a microphone attached to the performer. The goal is to schedule lighting movements that are coordinated with the performer by anticipating his/her future position based upon these observations using filtering theory. Particle system based methods have experienced rapid development and have become an essential technique of contemporary filtering strategies. Hitherto, researchers have largely focused on continuous state particle filters, ranging from traditional weighted particle filters to adaptive refining particle filters, readily able to perform path-space estimation and prediction. Herein, we compare the performance of a state-of-the-art refining particle filter to that of a novel discrete-space particle filter on the acoustic positioning problem. By discrete space particle filter we mean a Markov chain that counts particles in discretized cells of the signal state space in order to form an approximated unnormalized distribution of the signal state. For both filters mentioned above, we will examine issues like the mean time to localize a signal, the fidelity of filter estimates at various signal to noise ratios, computational costs, and the effect of signal

  19. Discrete Particle Swarm Optimization Routing Protocol for Wireless Sensor Networks with Multiple Mobile Sinks

    PubMed Central

    Yang, Jin; Liu, Fagui; Cao, Jianneng; Wang, Liangming

    2016-01-01

    Mobile sinks can achieve load-balancing and energy-consumption balancing across the wireless sensor networks (WSNs). However, the frequent change of the paths between source nodes and the sinks caused by sink mobility introduces significant overhead in terms of energy and packet delays. To enhance network performance of WSNs with mobile sinks (MWSNs), we present an efficient routing strategy, which is formulated as an optimization problem and employs the particle swarm optimization algorithm (PSO) to build the optimal routing paths. However, the conventional PSO is insufficient to solve discrete routing optimization problems. Therefore, a novel greedy discrete particle swarm optimization with memory (GMDPSO) is put forward to address this problem. In the GMDPSO, particle’s position and velocity of traditional PSO are redefined under discrete MWSNs scenario. Particle updating rule is also reconsidered based on the subnetwork topology of MWSNs. Besides, by improving the greedy forwarding routing, a greedy search strategy is designed to drive particles to find a better position quickly. Furthermore, searching history is memorized to accelerate convergence. Simulation results demonstrate that our new protocol significantly improves the robustness and adapts to rapid topological changes with multiple mobile sinks, while efficiently reducing the communication overhead and the energy consumption. PMID:27428971

  20. Discrete Element Modeling of the Mobilization of Coarse Gravel Beds by Finer Gravel Particles

    NASA Astrophysics Data System (ADS)

    Hill, K. M.; Tan, D.

    2012-12-01

    Recent research has shown that the addition of fine gravel particles to a coarse bed will mobilize the coarser bed, and that the effect is sufficiently strong that a pulse of fine gravel particles can mobilize an impacted coarser bed. Recent flume experiments have demonstrated that the degree of bed mobilization by finer particles is primarily dependent on the particle size ratio of the coarse and fine particles, rather than absolute size of either particle, provided both particles are sufficiently large. However, the mechanism behind the mobilization is not understood. It has previously been proposed that the mechanism is driven by a combination of geometric effects and hydraulic effects. For example, it has been argued that smaller particles fill in gaps along the bed, resulting in a smoother bed over which the larger particles are less likely to be disentrained and a reduced near-bed flow velocity and subsequent increased drag on protruding particles. Altered near-bed turbulence has also been cited as playing an important role. We perform simulations using the discrete element method with one-way fluid-solid coupling to conduct simulations of mobilization of a gravel bed by fine gravel particles. By independently and artificially controlling average and fluctuating velocity profiles, we systematically investigate the relative role that may be played by particle-particle interactions, average near-bed velocity profiles, and near-bed turbulence statistics. The simulations indicate that the relative importance of these mechanisms changes with the degree of mobilization of the bed. For higher bed mobility similar to bed sheets, particle-particle interactions, plays a significant role in an apparent rheology in the bed sheets, not unlike that observed in a dense granular flow of particles of different sizes. For conditions closer to a critical shear stress for bedload transport, the near-bed velocity profiles and turbulence statistics become increasingly important.

  1. Efficient implementation of superquadric particles in Discrete Element Method within an open-source framework

    NASA Astrophysics Data System (ADS)

    Podlozhnyuk, Alexander; Pirker, Stefan; Kloss, Christoph

    2016-09-01

    Particle shape representation is a fundamental problem in the Discrete Element Method (DEM). Spherical particles with well known contact force models remain popular in DEM due to their relative simplicity in terms of ease of implementation and low computational cost. However, in real applications particles are mostly non-spherical, and more sophisticated particle shape models, like superquadric shape, must be introduced in DEM. The superquadric shape can be considered as an extension of spherical or ellipsoidal particles and can be used for modeling of spheres, ellipsoids, cylinder-like and box(dice)-like particles just varying five shape parameters. In this study we present an efficient C++ implementation of superquadric particles within the open-source and parallel DEM package LIGGGHTS. To reduce computational time several ideas are employed. In the particle-particle contact detection routine we use the minimum bounding spheres and the oriented bounding boxes to reduce the number of potential contact pairs. For the particle-wall contact an accurate analytical solution was found. We present all necessary mathematics for the contact detection and contact force calculation. The superquadric DEM code implementation was verified on test cases such as angle of repose and hopper/silo discharge. The simulation results are in good agreement with experimental data and are presented in this paper. We show adequacy of the superquadric shape model and robustness of the implemented superquadric DEM code.

  2. Improved discrete ordinates calculations for an approximate model of neutral particle transport in ducts

    SciTech Connect

    Garcia, R.D.M.; Ono, S.

    1999-09-01

    An improved implementation of the discrete ordinates method for computing neutral particle transport in ducts is presented. The considered one-dimensional model makes use of two basic functions to represent the transverse and azimuthal dependencies of the particle angular flux in the duct. It is shown that if the problem is decomposed into uncollided and collided problems prior to using the discrete ordinates approximation, the number of ordinates necessary to achieve a desired degree of accuracy in the solution can be greatly reduced, especially for long ducts with significant wall absorption. Further savings in computer time can be attained by employing a composite quadrature based on a (nonstandard) half-range quadrature that can be generated in an effective and efficient way with one of the classical methods in the constructive theory of orthogonal polynomials.

  3. A hybrid particle/continuum approach for nonequilibrium hypersonic flows

    NASA Astrophysics Data System (ADS)

    Wang, Wen-Lan

    A hybrid particle-continuum computational framework is developed and presented for simulating nonequilibrium hypersonic flows, aimed to be more accurate than conventional continuum methods and faster than particle methods. The frame work consists of the direct simulation Monte Carlo-Information Preservation (DSMC-IP) method coupled with a Navier-Stokes solver. Since the DSMC-IP method provides the macroscopic information at each time step, determination of the continuum fluxes across the interface between the particle and continuum domains becomes straightforward. Buffer and reservoir calls are introduced in the continuum domain and work as an extension of the particle domain. At the end of the particle movement phase, particles in either particle or buffer cells are retained. All simulated particles in the reservoir cells are first deleted for each time, step and re-generated based on the local cell values. The microscopic velocities for the newly generated particles are initialized to the Chapman-Enskog distribution using an acceptance-rejection scheme. Continuum breakdown in a flow is defined as when the continuum solution departs from the particle solution to at least 5%. Numerical investigations show that a Knudsen-number-like parameter can best predict the continuum breakdown in the flows of interest. Numerical experiments of hypersonic flows over a simple blunted cone and a much more complex hollow cylinder/flare are conducted. The solutions for the two geometries considered from the hybrid framework are compared with experimental data and pure particle solutions. Generally speaking, it is concluded that the hybrid approach works quite well. In the blunted cone flow, numerical accuracy is improved when 10 layers of buffer cells are employed and the continuum breakdown cut-off value is set to be 0.03. In the hollow cylinder/flare hybrid simulation, the size of the separation zone near the conjunction of the cylinder and flare is improved from the initial

  4. The three-dimensional, discrete ordinates neutral particle transport code TORT: An overview

    SciTech Connect

    Azmy, Y.Y.

    1996-12-31

    The centerpiece of the Discrete Ordinates Oak Ridge System (DOORS), the three-dimensional neutral particle transport code TORT is reviewed. Its most prominent features pertaining to large applications, such as adjustable problem parameters, memory management, and coarse mesh methods, are described. Advanced, state-of-the-art capabilities including acceleration and multiprocessing are summarized here. Future enhancement of existing graphics and visualization tools is briefly presented.

  5. Discrete-element modelling and smoothed particle hydrodynamics: potential in the environmental sciences.

    PubMed

    Cleary, Paul W; Prakash, Mahesh

    2004-09-15

    Particle-based simulation methods, such as the discrete-element method and smoothed particle hydrodynamics, have specific advantages in modelling complex three-dimensional (3D) environmental fluid and particulate flows. The theory of both these methods and their relative advantages compared with traditional methods will be discussed. Examples of 3D flows on realistic topography illustrate the environmental application of these methods. These include the flooding of a river valley as a result of a dam collapse, coastal inundation by a tsunami, volcanic lava flow and landslides. Issues related to validation and quality data availability are also discussed. PMID:15306427

  6. Discrete particle model for bedload sediment transport in the surf zone

    NASA Astrophysics Data System (ADS)

    Calantoni, Joseph

    2002-04-01

    Predicting the evolution of nearshore bathymetry from the highest uprush of the swash offshore to the location of wave breaking is a difficult problem of significant importance, with economic, legal, engineering, scientific, and military implications for coastal environments. Despite the apparent accessibility of the phenomena of interest, namely, the motion of sand under the forcing of waves and currents, the predictive capability of existing models for nearshore evolution is poor. A detailed study of the forces exerted on individual sand grains is undertaken in an effort to elucidate sediment transport mechanisms in the surf zone. New results indicate that fluid acceleration is a particularly important feature of surf zone transport; likewise, the processes of particle size segregation and the role of particle shape are newly explored. The study methodology employs computer simulations that describe the collective and individual motions of discrete particles immersed in a Newtonian fluid having essentially arbitrary density and viscosity. In this study all particle properties are those of quartz sand, and the fluid properties correspond to saltwater at 20°C. Such discrete-particle models, having a basis in molecular dynamics studies, have a broad range of applications in addition to the sedimentological one of interest here; for example, similar methodologies have been applied to traffic flow, schooling fish, crowd control, and other problems in which the particulate nature of the phenomenon is of critical importance.

  7. Novel hybrid classified vector quantization using discrete cosine transform for image compression

    NASA Astrophysics Data System (ADS)

    Al-Fayadh, Ali; Hussain, Abir Jaafar; Lisboa, Paulo; Al-Jumeily, Dhiya

    2009-04-01

    We present a novel image compression technique using a classified vector Quantizer and singular value decomposition for the efficient representation of still images. The proposed method is called hybrid classified vector quantization. It involves a simple but efficient classifier-based gradient method in the spatial domain, which employs only one threshold to determine the class of the input image block, and uses three AC coefficients of discrete cosine transform coefficients to determine the orientation of the block without employing any threshold. The proposed technique is benchmarked with each of the standard vector quantizers generated using the k-means algorithm, standard classified vector quantizer schemes, and JPEG-2000. Simulation results indicate that the proposed approach alleviates edge degradation and can reconstruct good visual quality images with higher peak signal-to-noise ratio than the benchmarked techniques, or be competitive with them.

  8. Optimal design of sewer networks using cellular automata-based hybrid methods: Discrete and continuous approaches

    NASA Astrophysics Data System (ADS)

    Afshar, M. H.; Rohani, M.

    2012-01-01

    In this article, cellular automata based hybrid methods are proposed for the optimal design of sewer networks and their performance is compared with some of the common heuristic search methods. The problem of optimal design of sewer networks is first decomposed into two sub-optimization problems which are solved iteratively in a two stage manner. In the first stage, the pipe diameters of the network are assumed fixed and the nodal cover depths of the network are determined by solving a nonlinear sub-optimization problem. A cellular automata (CA) method is used for the solution of the optimization problem with the network nodes considered as the cells and their cover depths as the cell states. In the second stage, the nodal cover depths calculated from the first stage are fixed and the pipe diameters are calculated by solving a second nonlinear sub-optimization problem. Once again a CA method is used to solve the optimization problem of the second stage with the pipes considered as the CA cells and their corresponding diameters as the cell states. Two different updating rules are derived and used for the CA of the second stage depending on the treatment of the pipe diameters. In the continuous approach, the pipe diameters are considered as continuous variables and the corresponding updating rule is derived mathematically from the original objective function of the problem. In the discrete approach, however, an adhoc updating rule is derived and used taking into account the discrete nature of the pipe diameters. The proposed methods are used to optimally solve two sewer network problems and the results are presented and compared with those obtained by other methods. The results show that the proposed CA based hybrid methods are more efficient and effective than the most powerful search methods considered in this work.

  9. Generation of discrete scattering cross sections and demonstration of Monte Carlo charged particle transport in the Milagro IMC code package

    SciTech Connect

    Walsh, J. A.; Palmer, T. S.; Urbatsch, T. J.

    2013-07-01

    A new method for generating discrete scattering cross sections to be used in charged particle transport calculations is investigated. The method of data generation is presented and compared to current methods for obtaining discrete cross sections. The new, more generalized approach allows greater flexibility in choosing a cross section model from which to derive discrete values. Cross section data generated with the new method is verified through a comparison with discrete data obtained with an existing method. Additionally, a charged particle transport capability is demonstrated in the time-dependent Implicit Monte Carlo radiative transfer code package, Milagro. The implementation of this capability is verified using test problems with analytic solutions as well as a comparison of electron dose-depth profiles calculated with Milagro and an already-established electron transport code. An initial investigation of a preliminary integration of the discrete cross section generation method with the new charged particle transport capability in Milagro is also presented. (authors)

  10. Silicon PIN diode array hybrids for charged particle detection

    SciTech Connect

    Shapiro, S.L.; Dunwoodie, W.M.; Arens, J.F.; Jernigan, J.G.; Gaalema, S.

    1988-09-01

    We report on the design of silicon PIN diode array hybrids for use as charged particle detectors. A brief summary of the need for vertex detectors is presented. Circuitry, block diagrams and device specifications are included. 8 refs., 7 figs., 1 tab.

  11. A discrete mesoscopic particle model of the mechanics of a multi-constituent arterial wall.

    PubMed

    Witthoft, Alexandra; Yazdani, Alireza; Peng, Zhangli; Bellini, Chiara; Humphrey, Jay D; Karniadakis, George Em

    2016-01-01

    Blood vessels have unique properties that allow them to function together within a complex, self-regulating network. The contractile capacity of the wall combined with complex mechanical properties of the extracellular matrix enables vessels to adapt to changes in haemodynamic loading. Homogenized phenomenological and multi-constituent, structurally motivated continuum models have successfully captured these mechanical properties, but truly describing intricate microstructural details of the arterial wall may require a discrete framework. Such an approach would facilitate modelling interactions between or the separation of layers of the wall and would offer the advantage of seamless integration with discrete models of complex blood flow. We present a discrete particle model of a multi-constituent, nonlinearly elastic, anisotropic arterial wall, which we develop using the dissipative particle dynamics method. Mimicking basic features of the microstructure of the arterial wall, the model comprises an elastin matrix having isotropic nonlinear elastic properties plus anisotropic fibre reinforcement that represents the stiffer collagen fibres of the wall. These collagen fibres are distributed evenly and are oriented in four directions, symmetric to the vessel axis. Experimental results from biaxial mechanical tests of an artery are used for model validation, and a delamination test is simulated to demonstrate the new capabilities of the model. PMID:26790998

  12. Discrete element modelling of large scale particle systems—I: exact scaling laws

    NASA Astrophysics Data System (ADS)

    Feng, Y. T.; Owen, D. R. J.

    2014-06-01

    The discrete element method has emerged as a powerful predictive tool for the numerical modelling of many scientific and engineering problems involving discrete and discontinuous phenomena. There are nevertheless computational challenges to resolve before industrial scale applications can be effectively simulated. This multi-part paper aims to address some of the theoretical and computational issues central to achieving this goal. In the first part of this paper, a simple but generic theoretical framework is established for the development of a comprehensive set of scaling conditions, under which a scaled discrete element model can exactly reproduce the mechanical behaviour of a physical model. In particular, three basic physical quantities and their scale factors can be freely chosen. A special selection leads to a unique set of scale factors governing an exact scaling, which also gives rise to the requirement that all the interaction laws employed in a scaled model be scale-invariant. The subsequent examination reveals that most commonly used interaction laws, if all material (mechanical and physical) properties are treated as constant, do not possess such a feature and therefore cannot be directly employed in a scaled model. The problem can be solved by treating the scaled particles as pseudo-particles and by properly scaling the interaction laws. The resulting scaled interaction laws become scale-invariant and thus can be used in a scaled model.

  13. A discrete mesoscopic particle model of the mechanics of a multi-constituent arterial wall.

    PubMed

    Witthoft, Alexandra; Yazdani, Alireza; Peng, Zhangli; Bellini, Chiara; Humphrey, Jay D; Karniadakis, George Em

    2016-01-01

    Blood vessels have unique properties that allow them to function together within a complex, self-regulating network. The contractile capacity of the wall combined with complex mechanical properties of the extracellular matrix enables vessels to adapt to changes in haemodynamic loading. Homogenized phenomenological and multi-constituent, structurally motivated continuum models have successfully captured these mechanical properties, but truly describing intricate microstructural details of the arterial wall may require a discrete framework. Such an approach would facilitate modelling interactions between or the separation of layers of the wall and would offer the advantage of seamless integration with discrete models of complex blood flow. We present a discrete particle model of a multi-constituent, nonlinearly elastic, anisotropic arterial wall, which we develop using the dissipative particle dynamics method. Mimicking basic features of the microstructure of the arterial wall, the model comprises an elastin matrix having isotropic nonlinear elastic properties plus anisotropic fibre reinforcement that represents the stiffer collagen fibres of the wall. These collagen fibres are distributed evenly and are oriented in four directions, symmetric to the vessel axis. Experimental results from biaxial mechanical tests of an artery are used for model validation, and a delamination test is simulated to demonstrate the new capabilities of the model.

  14. A suspended-particle rosette multi-sampler for discrete biogeochemical sampling in low-particle-density waters

    SciTech Connect

    Breier, J. A.; Rauch, C. G.; McCartney, K.; Toner, B. M.; Fakra, S. C.; White, S. N.; German, C. R.

    2010-06-22

    To enable detailed investigations of early stage hydrothermal plume formation and abiotic and biotic plume processes we developed a new oceanographic tool. The Suspended Particulate Rosette sampling system has been designed to collect geochemical and microbial samples from the rising portion of deep-sea hydrothermal plumes. It can be deployed on a remotely operated vehicle for sampling rising plumes, on a wire-deployed water rosette for spatially discrete sampling of non-buoyant hydrothermal plumes, or on a fixed mooring in a hydrothermal vent field for time series sampling. It has performed successfully during both its first mooring deployment at the East Pacific Rise and its first remotely-operated vehicle deployments along the Mid-Atlantic Ridge. It is currently capable of rapidly filtering 24 discrete large-water-volume samples (30-100 L per sample) for suspended particles during a single deployment (e.g. >90 L per sample at 4-7 L per minute through 1 {mu}m pore diameter polycarbonate filters). The Suspended Particulate Rosette sampler has been designed with a long-term goal of seafloor observatory deployments, where it can be used to collect samples in response to tectonic or other events. It is compatible with in situ optical sensors, such as laser Raman or visible reflectance spectroscopy systems, enabling in situ particle analysis immediately after sample collection and before the particles alter or degrade.

  15. A hybrid continuous-discrete method for stochastic reaction–diffusion processes

    PubMed Central

    Zheng, Likun; Nie, Qing

    2016-01-01

    Stochastic fluctuations in reaction–diffusion processes often have substantial effect on spatial and temporal dynamics of signal transductions in complex biological systems. One popular approach for simulating these processes is to divide the system into small spatial compartments assuming that molecules react only within the same compartment and jump between adjacent compartments driven by the diffusion. While the approach is convenient in terms of its implementation, its computational cost may become prohibitive when diffusive jumps occur significantly more frequently than reactions, as in the case of rapid diffusion. Here, we present a hybrid continuous-discrete method in which diffusion is simulated using continuous approximation while reactions are based on the Gillespie algorithm. Specifically, the diffusive jumps are approximated as continuous Gaussian random vectors with time-dependent means and covariances, allowing use of a large time step, even for rapid diffusion. By considering the correlation among diffusive jumps, the approximation is accurate for the second moment of the diffusion process. In addition, a criterion is obtained for identifying the region in which such diffusion approximation is required to enable adaptive calculations for better accuracy. Applications to a linear diffusion system and two nonlinear systems of morphogens demonstrate the effectiveness and benefits of the new hybrid method. PMID:27703710

  16. Intersecting dilated convex polyhedra method for modeling complex particles in discrete element method

    PubMed Central

    Nye, Ben; Kulchitsky, Anton V; Johnson, Jerome B

    2014-01-01

    This paper describes a new method for representing concave polyhedral particles in a discrete element method as unions of convex dilated polyhedra. This method offers an efficient way to simulate systems with a large number of (generally concave) polyhedral particles. The method also allows spheres, capsules, and dilated triangles to be combined with polyhedra using the same approach. The computational efficiency of the method is tested in two different simulation setups using different efficiency metrics for seven particle types: spheres, clusters of three spheres, clusters of four spheres, tetrahedra, cubes, unions of two octahedra (concave), and a model of a computer tomography scan of a lunar simulant GRC-3 particle. It is shown that the computational efficiency of the simulations degrades much slower than the increase in complexity of the particles in the system. The efficiency of the method is based on the time coherence of the system, and an efficient and robust distance computation method between polyhedra as particles never intersect for dilated particles. PMID:26300584

  17. Error analysis of backscatter from discrete dipole approximation for different ice particle shapes

    NASA Astrophysics Data System (ADS)

    Liu, Chun-Lei; Illingworth, Anthony J.

    Ice sphere backscatter has been calculated using both Mie theory and the discrete dipole approximation (DDA) at a wavelength of 3.2 mm (94 GHz). The electric dipole, magnetic dipole and electric quadrupole contributions to spherical particle backscatter have been analyzed. The results show that there is a resonance area around particle size parameter of 1.5, where the calculated backscatter errors are very large due to the neglect of the magnetic dipole, and this is confirmed by applying Mie theory to 8.66 mm (35 GHz) and 3.21 cm (X-band) wavelengths. Based on the backscatter calculation using a cube and a hexagon column randomly oriented in space, it was found that the backscatter error from the inaccurate representation of the particle surface shape is much smaller than that from the neglect of the magnetic dipole, and the resonance occurs at different particle sizes depending upon the exact particle shapes. At a wavelength of 3.2 mm, the particle shape has little effect on backscatter when volume-equivalent spherical particle radius rv < 500 μm, and Rayleigh backscatter can be used as a reasonable approximation for rv < 300 μm.

  18. Simulation of the dynamic packing behavior of preparative chromatography columns via discrete particle modeling.

    PubMed

    Dorn, Martin; Hekmat, Dariusch

    2016-03-01

    Preparative packed-bed chromatography using polymer-based, compressible, porous resins is a powerful method for purification of macromolecular bioproducts. During operation, a complex, hysteretic, thus, history-dependent packed bed behavior is often observed but theoretical understanding of the causes is limited. Therefore, a rigorous modeling approach of the chromatography column on the particle scale has been made which takes into account interparticle micromechanics and fluid-particle interactions for the first time. A three-dimensional deterministic model was created by applying Computational Fluid Dynamics (CFD) coupled with the Discrete Element Method (DEM). The column packing behavior during either flow or mechanical compression was investigated in-silico and in laboratory experiments. A pronounced axial compression-relaxation profile was identified that differed for both compression strategies. Void spaces were clearly visible in the packed bed after compression. It was assumed that the observed bed inhomogeneity was because of a force-chain network at the particle scale. The simulation satisfactorily reproduced the measured behavior regarding packing compression as well as pressure-flow dependency. Furthermore, the particle Young's modulus and particle-wall friction as well as interparticle friction were identified as crucial parameters affecting packing dynamics. It was concluded that compaction of the chromatographic bed is rather because of particle rearrangement than particle deformation. © 2015 American Institute of Chemical Engineers Biotechnol. Prog., 32:363-371, 2016.

  19. Particle tracking approach for transport in three-dimensional discrete fracture networks: Particle tracking in 3-D DFNs

    SciTech Connect

    Makedonska, Nataliia; Painter, Scott L.; Bui, Quan M.; Gable, Carl W.; Karra, Satish

    2015-09-16

    The discrete fracture network (DFN) model is a method to mimic discrete pathways for fluid flow through a fractured low-permeable rock mass, and may be combined with particle tracking simulations to address solute transport. However, experience has shown that it is challenging to obtain accurate transport results in three-dimensional DFNs because of the high computational burden and difficulty in constructing a high-quality unstructured computational mesh on simulated fractures. We present a new particle tracking capability, which is adapted to control volume (Voronoi polygons) flow solutions on unstructured grids (Delaunay triangulations) on three-dimensional DFNs. The locally mass-conserving finite-volume approach eliminates mass balance-related problems during particle tracking. The scalar fluxes calculated for each control volume face by the flow solver are used to reconstruct a Darcy velocity at each control volume centroid. The groundwater velocities can then be continuously interpolated to any point in the domain of interest. The control volumes at fracture intersections are split into four pieces, and the velocity is reconstructed independently on each piece, which results in multiple groundwater velocities at the intersection, one for each fracture on each side of the intersection line. This technique enables detailed particle transport representation through a complex DFN structure. Verified for small DFNs, the new simulation capability enables numerical experiments on advective transport in large DFNs to be performed. As a result, we demonstrate this particle transport approach on a DFN model using parameters similar to those of crystalline rock at a proposed geologic repository for spent nuclear fuel in Forsmark, Sweden.

  20. Particle tracking approach for transport in three-dimensional discrete fracture networks: Particle tracking in 3-D DFNs

    DOE PAGES

    Makedonska, Nataliia; Painter, Scott L.; Bui, Quan M.; Gable, Carl W.; Karra, Satish

    2015-09-16

    The discrete fracture network (DFN) model is a method to mimic discrete pathways for fluid flow through a fractured low-permeable rock mass, and may be combined with particle tracking simulations to address solute transport. However, experience has shown that it is challenging to obtain accurate transport results in three-dimensional DFNs because of the high computational burden and difficulty in constructing a high-quality unstructured computational mesh on simulated fractures. We present a new particle tracking capability, which is adapted to control volume (Voronoi polygons) flow solutions on unstructured grids (Delaunay triangulations) on three-dimensional DFNs. The locally mass-conserving finite-volume approach eliminates massmore » balance-related problems during particle tracking. The scalar fluxes calculated for each control volume face by the flow solver are used to reconstruct a Darcy velocity at each control volume centroid. The groundwater velocities can then be continuously interpolated to any point in the domain of interest. The control volumes at fracture intersections are split into four pieces, and the velocity is reconstructed independently on each piece, which results in multiple groundwater velocities at the intersection, one for each fracture on each side of the intersection line. This technique enables detailed particle transport representation through a complex DFN structure. Verified for small DFNs, the new simulation capability enables numerical experiments on advective transport in large DFNs to be performed. As a result, we demonstrate this particle transport approach on a DFN model using parameters similar to those of crystalline rock at a proposed geologic repository for spent nuclear fuel in Forsmark, Sweden.« less

  1. Digital atom interferometer with single particle control on a discretized space-time geometry

    PubMed Central

    Steffen, Andreas; Alberti, Andrea; Alt, Wolfgang; Belmechri, Noomen; Hild, Sebastian; Karski, Michał; Widera, Artur; Meschede, Dieter

    2012-01-01

    Engineering quantum particle systems, such as quantum simulators and quantum cellular automata, relies on full coherent control of quantum paths at the single particle level. Here we present an atom interferometer operating with single trapped atoms, where single particle wave packets are controlled through spin-dependent potentials. The interferometer is constructed from a sequence of discrete operations based on a set of elementary building blocks, which permit composing arbitrary interferometer geometries in a digital manner. We use this modularity to devise a space-time analogue of the well-known spin echo technique, yielding insight into decoherence mechanisms. We also demonstrate mesoscopic delocalization of single atoms with a separation-to-localization ratio exceeding 500; this result suggests their utilization beyond quantum logic applications as nano-resolution quantum probes in precision measurements, being able to measure potential gradients with precision 5 × 10-4 in units of gravitational acceleration g. PMID:22665771

  2. Pressure calculation in hybrid particle-field simulations

    SciTech Connect

    Milano, Giuseppe; Kawakatsu, Toshihiro

    2010-12-07

    In the framework of a recently developed scheme for a hybrid particle-field simulation techniques where self-consistent field (SCF) theory and particle models (molecular dynamics) are combined [J. Chem. Phys. 130, 214106 (2009)], we developed a general formulation for the calculation of instantaneous pressure and stress tensor. The expressions have been derived from statistical mechanical definition of the pressure starting from the expression for the free energy functional in the SCF theory. An implementation of the derived formulation suitable for hybrid particle-field molecular dynamics-self-consistent field simulations is described. A series of test simulations on model systems are reported comparing the calculated pressure with those obtained from standard molecular dynamics simulations based on pair potentials.

  3. A hybrid FEM-DEM approach to the simulation of fluid flow laden with many particles

    NASA Astrophysics Data System (ADS)

    Casagrande, Marcus V. S.; Alves, José L. D.; Silva, Carlos E.; Alves, Fábio T.; Elias, Renato N.; Coutinho, Alvaro L. G. A.

    2016-01-01

    In this work we address a contribution to the study of particle laden fluid flows in scales smaller than TFM (two-fluid models). The hybrid model is based on a Lagrangian-Eulerian approach. A Lagrangian description is used for the particle system employing the discrete element method (DEM), while a fixed Eulerian mesh is used for the fluid phase modeled by the finite element method (FEM). The resulting coupled DEM-FEM model is integrated in time with a subcycling scheme. The aforementioned scheme is applied in the simulation of a seabed current to analyze which mechanisms lead to the emergence of bedload transport and sediment suspension, and also quantify the effective viscosity of the seabed in comparison with the ideal no-slip wall condition. A simulation of a salt plume falling in a fluid column is performed, comparing the main characteristics of the system with an experiment.

  4. Discrete Particle Simulation Techniques for the Analysis of Colliding and Flowing Particulate Media

    NASA Astrophysics Data System (ADS)

    Mukherjee, Debanjan

    Flowing particulate media are ubiquitous in a wide spectrum of applications that include transport systems, fluidized beds, manufacturing and materials processing technologies, energy conversion and propulsion technologies, sprays, jets, slurry flows, and biological flows. The discrete nature of the media, along with their underlying coupled multi-physical interactions can lead to a variety of interesting phenomena, many of which are unique to such media - for example, turbulent diffusion and preferential concentration in particle laden flows, and soliton like excitation patterns in a vibrated pile of granular material. This dissertation explores the utility of numerical simulations based on the discrete element method and collision driven particle dynamics methods for analyzing flowing particulate media. Such methods are well-suited to handle phenomena involving particulate, granular, and discontinuous materials, and often provide abilities to tackle complicated physical phenomena, for which pursuing continuum based approaches might be difficult or sometimes insufficient. A detailed discussion on hierarchically representing coupled, multi-physical phenomena through simple models for underlying physical interactions is presented. Appropriate physical models for mechanical contact, conductive and convective heat exchange, fluid-particle interactions, adhesive and near-field effects, and interaction with applied electromagnetic fields are presented. Algorithmic details on assembling the interaction models into a large-scale simulation framework have been elaborated with illustrations. The assembled frameworks were used to develop a computer simulation library (named `Software Library for Discrete Element Simulations' (SLIDES) for the sake of reference and continued future development efforts) and aspects of the architecture and development of this library have also been addressed. This is an object-oriented discrete particle simulation library developed in Fortran

  5. Simulation of River Bluffs and Slip-Off Slopes With a Discrete Particle-Based Model

    NASA Astrophysics Data System (ADS)

    Lancaster, S. T.; Zunka, J. P.; Tucker, G. E.

    2013-12-01

    A discrete particle-based model simulates evolution of two-dimensional valley cross sections similar to those produced by bedrock meandering rivers and thereby suggests that characteristic features such as overhanging cliffs and talus slopes are dependent on specific relationships among process rates. Discrete coordinates on a gridded cross-section define locations of particles of intact bedrock, sediment (loose material with half the bulk density of bedrock), water, or air on that grid, and each particle of rock or sediment has a unique (or zero) concentration of terrestrial cosmogenic nuclides (TCNs). Stochastic processes determine both the possible locations of process actions and the results of those actions. Stochastic discharges generate boundary shear stresses, calculated by an approximation to the ray-isovel model, that determine removal probabilities for candidate particles of bedrock or sediment from the boundary of a self-formed channel. An asymmetric probability distribution governs the selection of candidate particles on the wetted perimeter and drives asymmetric fluvial erosion and transport that can undermine adjacent slopes, so that the channel migrates laterally. Sediment is produced from intact bedrock by weathering and rock fall. The latter acts only on candidate bedrock particles that are undermined and exposed at the surface. Weathering produces two sediment particles from one of bedrock, and thereby inflates the surface, when slope-normal random walks from candidate sites on the surface end at bedrock particles, so that the sediment-bedrock interface is irregular and discontinuous. Diffusive transport moves candidate particles on random walks in random directions along the surface, where transition probabilities depend on local topography. TCNs are produced when the randomly situated and oriented random walks of cosmic rays end at bedrock or sediment, and not water, particles. The model produces asymmetric channels and valley cross sections

  6. Coupled discrete element and smoothed particle hydrodynamics simulations of the die filling process

    NASA Astrophysics Data System (ADS)

    Breinlinger, Thomas; Kraft, Torsten

    2015-08-01

    Die filling is an important part of the powder compaction process chain, where defects in the final part can be introduced—or prevented. Simulation of this process is therefore a goal for many part producers and has been studied by some researchers already. In this work, we focus on the influence of the surrounding air on the powder flow. We demonstrate the implementing and coupling of the discrete element method for the granular powder and the smoothed particle hydrodynamics method for the gas flow. Application of the method to the die filling process is demonstrated.

  7. Coupled discrete element and smoothed particle hydrodynamics simulations of the die filling process

    NASA Astrophysics Data System (ADS)

    Breinlinger, Thomas; Kraft, Torsten

    2016-11-01

    Die filling is an important part of the powder compaction process chain, where defects in the final part can be introduced—or prevented. Simulation of this process is therefore a goal for many part producers and has been studied by some researchers already. In this work, we focus on the influence of the surrounding air on the powder flow. We demonstrate the implementing and coupling of the discrete element method for the granular powder and the smoothed particle hydrodynamics method for the gas flow. Application of the method to the die filling process is demonstrated.

  8. A reduced complexity discrete particle model for understanding the sediment dynamics of steep upland river confluences

    NASA Astrophysics Data System (ADS)

    Tancock, M. J.; Lane, S. N.; Hardy, R. J.

    2012-12-01

    There has been a significant amount of research conducted in order to understand the flow fields at natural river confluences. Much of this has been made possible due to advances in the use of Computational Fluid Dynamics (CFD). However, much of this research has been conducted on river confluences with negligible water surface slopes and any understanding of the sediment dynamics is largely implied from the flow fields. Therefore, a key challenge is to understand the flow and sediment dynamics of steep river confluences with dynamic boundaries. Two numerical modelling developments are presented which together are capable of increasing our understanding of the sediment dynamics of steep river confluences. The first is the application of a Height-of-Liquid (HOL) model within a CFD framework to explicitly solve the water surface elevation. This is a time-dependent, multiphase treatment of the fluid dynamics which solves for the change in volume of water and air in each vertical column of the mesh. The second is the development of a reduced complexity discrete particle transport model which uses the change in momentum on a spherical particle to predict the transport paths through the flow field determined from CFD simulations. The performance of the two models is tested using field data from a series of highly dynamic, steep gravel-bed confluences on a braidplain of the Borgne d'Arolla, Switzerland. The HOL model is validated against the water surface elevation and flow velocity data and is demonstrated to provide a reliable representation of the flow field in fast-flowing, supercritical flows. In order to validate the discrete particle model, individual particles were tracked using electronic tacheometry. The model is demonstrated to accurately represent the particle tracks obtained in the field and provides a new methodology to understand the dynamic morphology of braid plains.

  9. Discrete particle simulations and experiments on the collapse of wet granular columns

    NASA Astrophysics Data System (ADS)

    Gabrieli, Fabio; Artoni, Riccardo; Santomaso, Andrea; Cola, Simonetta

    2013-10-01

    Small quantities of liquid in a granular material control the flow dynamics as well as the triggering and jamming phases. In order to study this problem, some experimental collapse tests conducted in a rectangular box were reproduced with a 1:1 scale numerical model using the Discrete Element Method. In simulations the effect of the capillary bridges has been investigated implementing a mid-range attractive force between particles based on the minimum energy approach. Also a bonding-debonding mechanism was incorporated in the algorithm and the volume of each sessile drop on the particle surface was considered during its motion. The influence of some variables was investigated with respect to the final slope profiles and the runout lengths: the initial liquid content, the particle size, the solid density, the liquid surface tension, and the liquid-solid contact angle. Also the crucial effect of the confinement walls on the collapse phenomenon was investigated: wet particles adhere to the lateral walls providing a higher flow resistance in comparison to the same material in dry conditions. It was observed that particles with largest path-lengths are localized near the movable wall at a middle-height of the initial column sample. Other particles at the surface moves in a rigid way especially if they were wet and with a low solid density. The "fidelity" of each particle with respect to the nearest neighbours was evaluated allowing to recognize the emergence of clusters of particles and rigid parts, to extract the failure surface and to localize where debonding mechanisms concentrate in the wet case.

  10. Development of perturbation Monte Carlo methods for polarized light transport in a discrete particle scattering model.

    PubMed

    Nguyen, Jennifer; Hayakawa, Carole K; Mourant, Judith R; Venugopalan, Vasan; Spanier, Jerome

    2016-05-01

    We present a polarization-sensitive, transport-rigorous perturbation Monte Carlo (pMC) method to model the impact of optical property changes on reflectance measurements within a discrete particle scattering model. The model consists of three log-normally distributed populations of Mie scatterers that approximate biologically relevant cervical tissue properties. Our method provides reflectance estimates for perturbations across wavelength and/or scattering model parameters. We test our pMC model performance by perturbing across number densities and mean particle radii, and compare pMC reflectance estimates with those obtained from conventional Monte Carlo simulations. These tests allow us to explore different factors that control pMC performance and to evaluate the gains in computational efficiency that our pMC method provides. PMID:27231642

  11. Development of perturbation Monte Carlo methods for polarized light transport in a discrete particle scattering model

    PubMed Central

    Nguyen, Jennifer; Hayakawa, Carole K.; Mourant, Judith R.; Venugopalan, Vasan; Spanier, Jerome

    2016-01-01

    We present a polarization-sensitive, transport-rigorous perturbation Monte Carlo (pMC) method to model the impact of optical property changes on reflectance measurements within a discrete particle scattering model. The model consists of three log-normally distributed populations of Mie scatterers that approximate biologically relevant cervical tissue properties. Our method provides reflectance estimates for perturbations across wavelength and/or scattering model parameters. We test our pMC model performance by perturbing across number densities and mean particle radii, and compare pMC reflectance estimates with those obtained from conventional Monte Carlo simulations. These tests allow us to explore different factors that control pMC performance and to evaluate the gains in computational efficiency that our pMC method provides. PMID:27231642

  12. Discharge flow of a bidisperse granular media from a silo: Discrete particle simulations

    NASA Astrophysics Data System (ADS)

    Zhou, Y.; Ruyer, P.; Aussillous, P.

    2015-12-01

    Discrete particle simulations are used to study two-dimensional discharge flow from a silo using both monodisperse and bidisperse mixtures. The density and the velocity profiles through the aperture are measured. In the monodisperse case, two particles' diameters are studied for different outlet diameters. In the bidisperse case, we varied the fine mass fraction of the mixture. In all cases, the density and the velocity profiles are found to follow the same self-similar law. Based on these observations and the previous work of Benyamine et al., a physical model is proposed to describe the flow of bidisperse mixtures giving an explicit expression for the flow rate that is in good agreement with the results.

  13. Discharge flow of a bidisperse granular media from a silo: Discrete particle simulations.

    PubMed

    Zhou, Y; Ruyer, P; Aussillous, P

    2015-12-01

    Discrete particle simulations are used to study two-dimensional discharge flow from a silo using both monodisperse and bidisperse mixtures. The density and the velocity profiles through the aperture are measured. In the monodisperse case, two particles' diameters are studied for different outlet diameters. In the bidisperse case, we varied the fine mass fraction of the mixture. In all cases, the density and the velocity profiles are found to follow the same self-similar law. Based on these observations and the previous work of Benyamine et al., a physical model is proposed to describe the flow of bidisperse mixtures giving an explicit expression for the flow rate that is in good agreement with the results. PMID:26764679

  14. Discharge flow of a bidisperse granular media from a silo: Discrete particle simulations.

    PubMed

    Zhou, Y; Ruyer, P; Aussillous, P

    2015-12-01

    Discrete particle simulations are used to study two-dimensional discharge flow from a silo using both monodisperse and bidisperse mixtures. The density and the velocity profiles through the aperture are measured. In the monodisperse case, two particles' diameters are studied for different outlet diameters. In the bidisperse case, we varied the fine mass fraction of the mixture. In all cases, the density and the velocity profiles are found to follow the same self-similar law. Based on these observations and the previous work of Benyamine et al., a physical model is proposed to describe the flow of bidisperse mixtures giving an explicit expression for the flow rate that is in good agreement with the results.

  15. GPU accelerated simulations of 3D deterministic particle transport using discrete ordinates method

    SciTech Connect

    Gong Chunye; Liu Jie; Chi Lihua; Huang Haowei; Fang Jingyue; Gong Zhenghu

    2011-07-01

    Graphics Processing Unit (GPU), originally developed for real-time, high-definition 3D graphics in computer games, now provides great faculty in solving scientific applications. The basis of particle transport simulation is the time-dependent, multi-group, inhomogeneous Boltzmann transport equation. The numerical solution to the Boltzmann equation involves the discrete ordinates (S{sub n}) method and the procedure of source iteration. In this paper, we present a GPU accelerated simulation of one energy group time-independent deterministic discrete ordinates particle transport in 3D Cartesian geometry (Sweep3D). The performance of the GPU simulations are reported with the simulations of vacuum boundary condition. The discussion of the relative advantages and disadvantages of the GPU implementation, the simulation on multi GPUs, the programming effort and code portability are also reported. The results show that the overall performance speedup of one NVIDIA Tesla M2050 GPU ranges from 2.56 compared with one Intel Xeon X5670 chip to 8.14 compared with one Intel Core Q6600 chip for no flux fixup. The simulation with flux fixup on one M2050 is 1.23 times faster than on one X5670.

  16. Simulation and Comparison of Particle Injection in an Indoor Environment Using the Species Transport and Discrete Phase Models

    SciTech Connect

    Zheng, Zhongquan C.; Wei, Zhenglun A.; Bennett, James S.; Yang, Xiaofan

    2012-12-11

    In simulating fluid/solid-particle multiphase -flows, various methods are available. One approach is the combined Euler-Lagrange method, which simulates the fluid phase flow in the Eulerian framework and the discrete phase (particle) motion in the Lagrangian framework simultaneously. The Lagrangian approach, where particle motion is determined by the current state of the fluid phase flow, is also called the discrete phase model (DPM), in the context of numerical flow simulation. In this method, the influence of the particle motions on the fluid flow can be included (two-way interactions) but are more commonly excluded (one-way interactions, when the discrete phase concentration is dilute. The other approach is to treat the particle number concentration as a continuous species, a necessarily passive quantity determined by the fluid flow, with no influences from the particles on the fluid flow (one-way interactions only), except to the extent the discrete phase “continuum” alters the overall fluid properties, such as density. In this paper, we compare these two methods with experimental data for an indoor environmental chamber. The effects of injection particle numbers and the related boundary conditions are investigated. In the Euler-Lagrange interaction or DPM model for incompressible flow, the Eulerian continuous phase is governed by the Reynolds-averaged N-S (RANS) equations. The motions of particles are governed by Newton’s second law. The effects of particle motions are communicated to the continuous phase through a force term in the RANS equations. The second formulation is a pure Eulerian type, where only the particle-number concentration is addressed, rather than the motion of each individual particle. The fluid flow is governed by the same RANS equations without the particle force term. The particle-number concentration is simulated by a species transport equation. Comparisons among the models and with experimental and literature data are presented

  17. Atomic filtering for hybrid continuous-variable/discrete-variable quantum optics.

    PubMed

    Zielińska, Joanna A; Beduini, Federica A; Lucivero, Vito Giovanni; Mitchell, Morgan W

    2014-10-20

    We demonstrate atomic filtering of frequency-degenerate photon pairs from a sub-threshold optical parametric oscillator (OPO). The filter, a modified Faraday anomalous dispersion optical filter (FADOF), achieves 70% peak transmission simultaneous with 57 dB out-of-band rejection and a 445 MHz transmission bandwidth. When applied to the OPO output, only the degenerate mode, containing one-mode squeezed vacuum, falls in the filter pass-band; all other modes are strongly suppressed. The high transmission preserves non-classical continuous-variable features, e.g. squeezing or non-gaussianity, while the high spectral purity allows reliable discrete-variable detection and heralding. Correlation and atomic absorption measurements indicate a spectral purity of 96% for the individual photons, and 98% for the photon pairs. These capabilities will enable generation of atom-resonant hybrid states, e.g. "Schrödinger kittens" obtained by photon subtraction from squeezed vacuum, making these exotic states available for quantum networking and atomic quantum metrology applications.

  18. Hybrid upwind discretization of nonlinear two-phase flow with gravity

    NASA Astrophysics Data System (ADS)

    Lee, S. H.; Efendiev, Y.; Tchelepi, H. A.

    2015-08-01

    Multiphase flow in porous media is described by coupled nonlinear mass conservation laws. For immiscible Darcy flow of multiple fluid phases, whereby capillary effects are negligible, the transport equations in the presence of viscous and buoyancy forces are highly nonlinear and hyperbolic. Numerical simulation of multiphase flow processes in heterogeneous formations requires the development of discretization and solution schemes that are able to handle the complex nonlinear dynamics, especially of the saturation evolution, in a reliable and computationally efficient manner. In reservoir simulation practice, single-point upwinding of the flux across an interface between two control volumes (cells) is performed for each fluid phase, whereby the upstream direction is based on the gradient of the phase-potential (pressure plus gravity head). This upwinding scheme, which we refer to as Phase-Potential Upwinding (PPU), is combined with implicit (backward-Euler) time discretization to obtain a Fully Implicit Method (FIM). Even though FIM suffers from numerical dispersion effects, it is widely used in practice. This is because of its unconditional stability and because it yields conservative, monotone numerical solutions. However, FIM is not unconditionally convergent. The convergence difficulties are particularly pronounced when the different immiscible fluid phases switch between co-current and counter-current states as a function of time, or (Newton) iteration. Whether the multiphase flow across an interface (between two control-volumes) is co-current, or counter-current, depends on the local balance between the viscous and buoyancy forces, and how the balance evolves in time. The sensitivity of PPU to small changes in the (local) pressure distribution exacerbates the problem. The common strategy to deal with these difficulties is to cut the timestep and try again. Here, we propose a Hybrid-Upwinding (HU) scheme for the phase fluxes, then HU is combined with implicit

  19. Existence and stability, and discrete BB and rank conditions, for general mixed-hybrid finite elements in elasticity

    NASA Technical Reports Server (NTRS)

    Xue, W.-M.; Atluri, S. N.

    1985-01-01

    In this paper, all possible forms of mixed-hybrid finite element methods that are based on multi-field variational principles are examined as to the conditions for existence, stability, and uniqueness of their solutions. The reasons as to why certain 'simplified hybrid-mixed methods' in general, and the so-called 'simplified hybrid-displacement method' in particular (based on the so-called simplified variational principles), become unstable, are discussed. A comprehensive discussion of the 'discrete' BB-conditions, and the rank conditions, of the matrices arising in mixed-hybrid methods, is given. Some recent studies aimed at the assurance of such rank conditions, and the related problem of the avoidance of spurious kinematic modes, are presented.

  20. Numerical sedimentation particle-size analysis using the Discrete Element Method

    NASA Astrophysics Data System (ADS)

    Bravo, R.; Pérez-Aparicio, J. L.; Gómez-Hernández, J. J.

    2015-12-01

    Sedimentation tests are widely used to determine the particle size distribution of a granular sample. In this work, the Discrete Element Method interacts with the simulation of flow using the well known one-way-coupling method, a computationally affordable approach for the time-consuming numerical simulation of the hydrometer, buoyancy and pipette sedimentation tests. These tests are used in the laboratory to determine the particle-size distribution of fine-grained aggregates. Five samples with different particle-size distributions are modeled by about six million rigid spheres projected on two-dimensions, with diameters ranging from 2.5 ×10-6 m to 70 ×10-6 m, forming a water suspension in a sedimentation cylinder. DEM simulates the particle's movement considering laminar flow interactions of buoyant, drag and lubrication forces. The simulation provides the temporal/spatial distributions of densities and concentrations of the suspension. The numerical simulations cannot replace the laboratory tests since they need the final granulometry as initial data, but, as the results show, these simulations can identify the strong and weak points of each method and eventually recommend useful variations and draw conclusions on their validity, aspects very difficult to achieve in the laboratory.

  1. Hybrid Modeling Method for a DEP Based Particle Manipulation

    PubMed Central

    Miled, Mohamed Amine; Gagne, Antoine; Sawan, Mohamad

    2013-01-01

    In this paper, a new modeling approach for Dielectrophoresis (DEP) based particle manipulation is presented. The proposed method fulfills missing links in finite element modeling between the multiphysic simulation and the biological behavior. This technique is amongst the first steps to develop a more complex platform covering several types of manipulations such as magnetophoresis and optics. The modeling approach is based on a hybrid interface using both ANSYS and MATLAB to link the propagation of the electrical field in the micro-channel to the particle motion. ANSYS is used to simulate the electrical propagation while MATLAB interprets the results to calculate cell displacement and send the new information to ANSYS for another turn. The beta version of the proposed technique takes into account particle shape, weight and its electrical properties. First obtained results are coherent with experimental results. PMID:23364197

  2. Hybrid finite element and Brownian dynamics method for charged particles

    NASA Astrophysics Data System (ADS)

    Huber, Gary A.; Miao, Yinglong; Zhou, Shenggao; Li, Bo; McCammon, J. Andrew

    2016-04-01

    Diffusion is often the rate-determining step in many biological processes. Currently, the two main computational methods for studying diffusion are stochastic methods, such as Brownian dynamics, and continuum methods, such as the finite element method. A previous study introduced a new hybrid diffusion method that couples the strengths of each of these two methods, but was limited by the lack of interactions among the particles; the force on each particle had to be from an external field. This study further develops the method to allow charged particles. The method is derived for a general multidimensional system and is presented using a basic test case for a one-dimensional linear system with one charged species and a radially symmetric system with three charged species.

  3. Hybrid mesh/particle meshless method for modeling geological flows with discontinuous transport properties

    NASA Astrophysics Data System (ADS)

    Bourantas, Georgios; Lavier, Luc; Claus, Susanne; Van Dam, Tonie; Bordas, Stephane

    2015-04-01

    meshless point collocation Eulerian method, while energy equation are solved using a set of particles, distributed over the spatial domain, with the solution interpolated back to the Eulerian grid at every time step. This hybrid approach allows for the accurate calculation of fine thermal structures, through the ease of adaptivity offered by the flexibility of the particle method. The approximation space is constructed using the Discretization Correction Particle Strength Exchange (DC PSE) method. The proposed scheme gives the capability of solving flow equations (Stokes flow) in fully irregular geometries while particles, "sprinkled" in the spatial domain, are used to solve convection-diffusion problems avoiding the oscillation produced in the Eulerian approach. The resulting algebraic linear systems were solved using direct solvers. Our hybrid approach can capture sharp variations of stresses and thermal gradients in problems with a strongly variable viscosity and thermal conductivity as demonstrated through various benchmarking test cases such as the development of Rayleigh-Taylor instabilities, viscous heating and flows with non-Newtonian rheology.

  4. Parallel machine scheduling with step-deteriorating jobs and setup times by a hybrid discrete cuckoo search algorithm

    NASA Astrophysics Data System (ADS)

    Guo, Peng; Cheng, Wenming; Wang, Yi

    2015-11-01

    This article considers the parallel machine scheduling problem with step-deteriorating jobs and sequence-dependent setup times. The objective is to minimize the total tardiness by determining the allocation and sequence of jobs on identical parallel machines. In this problem, the processing time of each job is a step function dependent upon its starting time. An individual extended time is penalized when the starting time of a job is later than a specific deterioration date. The possibility of deterioration of a job makes the parallel machine scheduling problem more challenging than ordinary ones. A mixed integer programming model for the optimal solution is derived. Due to its NP-hard nature, a hybrid discrete cuckoo search algorithm is proposed to solve this problem. In order to generate a good initial swarm, a modified Biskup-Hermann-Gupta (BHG) heuristic called MBHG is incorporated into the population initialization. Several discrete operators are proposed in the random walk of Lévy flights and the crossover search. Moreover, a local search procedure based on variable neighbourhood descent is integrated into the algorithm as a hybrid strategy in order to improve the quality of elite solutions. Computational experiments are executed on two sets of randomly generated test instances. The results show that the proposed hybrid algorithm can yield better solutions in comparison with the commercial solver CPLEX® with a one hour time limit, the discrete cuckoo search algorithm and the existing variable neighbourhood search algorithm.

  5. Effects of small particle numbers on long-term behaviour in discrete biochemical systems

    PubMed Central

    Ibrahim, Bashar; Dittrich, Peter

    2014-01-01

    Motivation: The functioning of many biological processes depends on the appearance of only a small number of a single molecular species. Additionally, the observation of molecular crowding leads to the insight that even a high number of copies of species do not guarantee their interaction. How single particles contribute to stabilizing biological systems is not well understood yet. Hence, we aim at determining the influence of single molecules on the long-term behaviour of biological systems, i.e. whether they can reach a steady state. Results: We provide theoretical considerations and a tool to analyse Systems Biology Markup Language models for the possibility to stabilize because of the described effects. The theory is an extension of chemical organization theory, which we called discrete chemical organization theory. Furthermore we scanned the BioModels Database for the occurrence of discrete chemical organizations. To exemplify our method, we describe an application to the Template model of the mitotic spindle assembly checkpoint mechanism. Availability and implementation: http://www.biosys.uni-jena.de/Services.html. Contact: bashar.ibrahim@uni-jena.de or dittrich@minet.uni-jena.de Supplementary information: Supplementary data are available at Bioinformatics online. PMID:25161236

  6. An optimized surface plasmon photovoltaic structure using energy transfer between discrete nano-particles.

    PubMed

    Lin, Albert; Fu, Sze-Ming; Chung, Yen-Kai; Lai, Shih-Yun; Tseng, Chi-Wei

    2013-01-14

    Surface plasmon enhancement has been proposed as a way to achieve higher absorption for thin-film photovoltaics, where surface plasmon polariton(SPP) and localized surface plasmon (LSP) are shown to provide dense near field and far field light scattering. Here it is shown that controlled far-field light scattering can be achieved using successive coupling between surface plasmonic (SP) nano-particles. Through genetic algorithm (GA) optimization, energy transfer between discrete nano-particles (ETDNP) is identified, which enhances solar cell efficiency. The optimized energy transfer structure acts like lumped-element transmission line and can properly alter the direction of photon flow. Increased in-plane component of wavevector is thus achieved and photon path length is extended. In addition, Wood-Rayleigh anomaly, at which transmission minimum occurs, is avoided through GA optimization. Optimized energy transfer structure provides 46.95% improvement over baseline planar cell. It achieves larger angular scattering capability compared to conventional surface plasmon polariton back reflector structure and index-guided structure due to SP energy transfer through mode coupling. Via SP mediated energy transfer, an alternative way to control the light flow inside thin-film is proposed, which can be more efficient than conventional index-guided mode using total internal reflection (TIR).

  7. Hydrodynamics of discrete-particle models of spherical colloids: a multiparticle collision dynamics simulation study.

    PubMed

    Poblete, Simón; Wysocki, Adam; Gompper, Gerhard; Winkler, Roland G

    2014-09-01

    We investigate the hydrodynamic properties of a spherical colloid model, which is composed of a shell of point particles by hybrid mesoscale simulations, which combine molecular dynamics simulations for the sphere with the multiparticle collision dynamics approach for the fluid. Results are presented for the center-of-mass and angular velocity correlation functions. The simulation results are compared with theoretical results for a rigid colloid obtained as a solution of the Stokes equation with no-slip boundary conditions. Similarly, analytical results of a point-particle model are presented, which account for the finite size of the simulated system. The simulation results agree well with both approaches on appropriative time scales; specifically, the long-time correlations are quantitatively reproduced. Moreover, a procedure is proposed to obtain the infinite-system-size diffusion coefficient based on a combination of simulation results and analytical predictions. In addition, we present the velocity field in the vicinity of the colloid and demonstrate its close agreement with the theoretical prediction. Our studies show that a point-particle model of a sphere is very well suited to describe the hydrodynamic properties of spherical colloids, with a significantly reduced numerical effort.

  8. C1-Continuous relative permeability and hybrid upwind discretization of three phase flow in porous media

    NASA Astrophysics Data System (ADS)

    Lee, S. H.; Efendiev, Y.

    2016-10-01

    Three-phase flow in a reservoir model has been a major challenge in simulation studies due to slowly convergent iterations in Newton solution of nonlinear transport equations. In this paper, we examine the numerical characteristics of three-phase flow and propose a consistent, "C1-continuous discretization" (to be clarified later) of transport equations that ensures a convergent solution in finite difference approximation. First, we examine three-phase relative permeabilities that are critical in solving nonlinear transport equations. Three-phase relative permeabilities are difficult to measure in the laboratory, and they are often correlated with two-phase relative permeabilities (e.g., oil-gas and water-oil systems). Numerical convergence of non-linear transport equations entails that three-phase relative permeability correlations are a monotonically increasing function of the phase saturation and the consistency conditions of phase transitions are satisfied. The Modified Stone's Method II and the Linear Interpolation Method for three-phase relative permeability are closely examined for their mathematical properties. We show that the Linear Interpolation Method yields C1-continuous three-phase relative permeabilities for smooth solutions if the two phase relative permeabilities are monotonic and continuously differentiable. In the second part of the paper, we extend a Hybrid-Upwinding (HU) method of two-phase flow (Lee, Efendiev and Tchelepi, ADWR 82 (2015) 27-38) to three phase flow. In the HU method, the phase flux is divided into two parts based on the driving forces (in general, it can be divided into several parts): viscous and buoyancy. The viscous-driven and buoyancy-driven fluxes are upwinded differently. Specifically, the viscous flux, which is always co-current, is upwinded based on the direction of the total velocity. The pure buoyancy-induced flux is shown to be only dependent on saturation distributions and counter-current. In three-phase flow, the

  9. Hybrid Particle Swarm Optimization for Hybrid Flowshop Scheduling Problem with Maintenance Activities

    PubMed Central

    Li, Jun-qing; Pan, Quan-ke; Mao, Kun

    2014-01-01

    A hybrid algorithm which combines particle swarm optimization (PSO) and iterated local search (ILS) is proposed for solving the hybrid flowshop scheduling (HFS) problem with preventive maintenance (PM) activities. In the proposed algorithm, different crossover operators and mutation operators are investigated. In addition, an efficient multiple insert mutation operator is developed for enhancing the searching ability of the algorithm. Furthermore, an ILS-based local search procedure is embedded in the algorithm to improve the exploitation ability of the proposed algorithm. The detailed experimental parameter for the canonical PSO is tuning. The proposed algorithm is tested on the variation of 77 Carlier and Néron's benchmark problems. Detailed comparisons with the present efficient algorithms, including hGA, ILS, PSO, and IG, verify the efficiency and effectiveness of the proposed algorithm. PMID:24883414

  10. Assembly of Hybrid Bacteriophage Qβ Virus-Like Particles

    PubMed Central

    Brown, Steven D.; Fiedler, Jason D.; Finn, M.G.

    2009-01-01

    Bacteriophage Qβ coat protein forms uniform virus-like particles when expressed recombinantly in a variety of organisms. We have inserted the IgG-binding Z domain at the carboxy terminus of the coat protein and coexpressed this chimeric subunit with native coat protein to create hybrid, IgG-binding virus-like particles. Extracellular osmolytes were found to have an effect on the incorporation efficiency of fusion proteins into VLPs in E. coli when a carbenicillin, but not a kanamycin, selection marker was used. The addition of sucrose to the growth media decreased incorporation efficiency; the osmoprotectant glycine betaine eliminated this effect. The decrease in efficiency was not observed when carbenicillin was omitted from the final expression culture. The addition of sodium chloride instead of sucrose gave rise to particles with a larger number of fusion proteins than the standard conditions. These results illustrate that cellular conditions should be taken into account even in apparently simple systems when natural or engineered protein nanoparticles are made. PMID:19848414

  11. Multi-objective flexible job-shop scheduling problem using modified discrete particle swarm optimization.

    PubMed

    Huang, Song; Tian, Na; Wang, Yan; Ji, Zhicheng

    2016-01-01

    Taking resource allocation into account, flexible job shop problem (FJSP) is a class of complex scheduling problem in manufacturing system. In order to utilize the machine resources rationally, multi-objective particle swarm optimization (MOPSO) integrating with variable neighborhood search is introduced to address FJSP efficiently. Firstly, the assignment rules (AL) and dispatching rules (DR) are provided to initialize the population. And then special discrete operators are designed to produce new individuals and earliest completion machine (ECM) is adopted in the disturbance operator to escape the optima. Secondly, personal-best archives (cognitive memories) and global-best archive (social memory), which are updated by the predefined non-dominated archive update strategy, are simultaneously designed to preserve non-dominated individuals and select personal-best positions and the global-best position. Finally, three neighborhoods are provided to search the neighborhoods of global-best archive for enhancing local search ability. The proposed algorithm is evaluated by using Kacem instances and Brdata instances, and a comparison with other approaches shows the effectiveness of the proposed algorithm for FJSP.

  12. Multi-objective flexible job-shop scheduling problem using modified discrete particle swarm optimization.

    PubMed

    Huang, Song; Tian, Na; Wang, Yan; Ji, Zhicheng

    2016-01-01

    Taking resource allocation into account, flexible job shop problem (FJSP) is a class of complex scheduling problem in manufacturing system. In order to utilize the machine resources rationally, multi-objective particle swarm optimization (MOPSO) integrating with variable neighborhood search is introduced to address FJSP efficiently. Firstly, the assignment rules (AL) and dispatching rules (DR) are provided to initialize the population. And then special discrete operators are designed to produce new individuals and earliest completion machine (ECM) is adopted in the disturbance operator to escape the optima. Secondly, personal-best archives (cognitive memories) and global-best archive (social memory), which are updated by the predefined non-dominated archive update strategy, are simultaneously designed to preserve non-dominated individuals and select personal-best positions and the global-best position. Finally, three neighborhoods are provided to search the neighborhoods of global-best archive for enhancing local search ability. The proposed algorithm is evaluated by using Kacem instances and Brdata instances, and a comparison with other approaches shows the effectiveness of the proposed algorithm for FJSP. PMID:27652008

  13. Understanding the mechanisms of sickle cell disease by simulations with a discrete particle model

    NASA Astrophysics Data System (ADS)

    Hui, Katrina; Lin, Guang; Pan, Wenxiao

    2013-01-01

    Sickle cell disease (SCD) is an inherited blood disorder characterized by rigid, sickle-shaped red blood cells (RBCs). Because of their rigidity and shape, sickle cells can get stuck in smaller blood vessels, causing blockages and depriving oxygen to tissues. This study develops and applies mathematical models to better understand the mechanism of SCD. Two-dimensional models of RBCs and blood vessels have been constructed by representing them as discrete particles interacting with different forces. The nonlinear, elastic property of healthy RBCs could be adequately reproduced using a cosine angle bending force and a worm-like chain spring force. With the ability to deform, RBCs can squeeze through narrow blood vessels. In modeling sickle cells as rigid bodies and applying repelling and friction forces from the blood vessel, this study shows that geometrical factors (dimensions of the sickle cell and blood vessels) as well as rigidity and adhesiveness of the sickle cell all play an important role in determining how, and if, sickle cells become trapped within narrow blood capillaries. With lack of data to validate the model, this study primarily provides a sensitivity analysis of factors influencing sickle cell occlusion and identified critical data to support future modeling.

  14. Collective behavior of self-propelling particles with kinematic constraints: The relation between the discrete and the continuous description

    NASA Astrophysics Data System (ADS)

    Ratushnaya, V. I.; Bedeaux, D.; Kulinskii, V. L.; Zvelindovsky, A. V.

    2007-07-01

    In two papers we proposed a continuum model for the dynamics of systems of self propelling particles with kinematic constraints on the velocities and discussed some of its properties. The model aims to be analogous to a discrete algorithm used in works by T. Vicsek et al. In this paper we derive the continuous hydrodynamic model from the discrete description. The similarities and differences between the resulting model and the hydrodynamic model postulated in our previous papers are discussed. The results clarify the assumptions used to obtain a continuous description.

  15. Hybrid Particle Code Simulations of Mars: The Energy Budget.

    NASA Astrophysics Data System (ADS)

    Brecht, S. H.; Ledvina, S. A.

    2015-12-01

    The results of our latest hybrid particle simulations using the HALFSHEL code are discussed. The presentation will address the energy budget of the solar wind interaction with Mars. The simulations produce loss rates that are very consistent with measured data, Brecht and Ledvina [2014], therefore inspection of the details of the interaction is now warranted. This paper will address the relationship between the energy flowing into the planet and the energy flowing away from the planet. The partition of the energy between fields, and individual ion species will be addressed as well as the amount of energy deposited in the neutral atmosphere by incoming solar wind plasma and during the process of ion loss caused by acceleration via electric fields. Brecht, S.H. and S.A. Ledvina (2014), "The role of the Martian crustal magnetic fields in controlling ionospheric loss," Geophys. Res. Lett., 41, 5340-5346, doi:10.1002/2014GL060841.

  16. Hybrid particle-field molecular dynamics simulation for polyelectrolyte systems.

    PubMed

    Zhu, You-Liang; Lu, Zhong-Yuan; Milano, Giuseppe; Shi, An-Chang; Sun, Zhao-Yan

    2016-04-14

    To achieve simulations on large spatial and temporal scales with high molecular chemical specificity, a hybrid particle-field method was proposed recently. This method is developed by combining molecular dynamics and self-consistent field theory (MD-SCF). The MD-SCF method has been validated by successfully predicting the experimentally observable properties of several systems. Here we propose an efficient scheme for the inclusion of electrostatic interactions in the MD-SCF framework. In this scheme, charged molecules are interacting with the external fields that are self-consistently determined from the charge densities. This method is validated by comparing the structural properties of polyelectrolytes in solution obtained from the MD-SCF and particle-based simulations. Moreover, taking PMMA-b-PEO and LiCF3SO3 as examples, the enhancement of immiscibility between the ion-dissolving block and the inert block by doping lithium salts into the copolymer is examined by using the MD-SCF method. By employing GPU-acceleration, the high performance of the MD-SCF method with explicit treatment of electrostatics facilitates the simulation study of many problems involving polyelectrolytes. PMID:27001709

  17. Quasi-discrete particle motion in an externally imposed, ordered structure in a dusty plasma at high magnetic field

    NASA Astrophysics Data System (ADS)

    Thomas, Edward; Konopka, Uwe; Lynch, Brian; Adams, Stephen; LeBlanc, Spencer; Merlino, Robert L.; Rosenberg, Marlene

    2015-11-01

    Dusty plasmas have been studied in argon, radio frequency (rf) glow discharge plasmas at magnetic fields up to 2.5 T where the electrons and ions are strongly magnetized. Plasmas are generated between two parallel plate electrodes where the lower, powered electrode is solid and the upper electrode supports a dual mesh consisting of #24 brass and #30 aluminum wire cloth. In this experiment, we study the formation of imposed ordered structures and particle dynamics as a function of magnetic field. Through observations of trapped particles and the quasi-discrete (i.e., "hopping") motion of particles between the trapping locations, it is possible to make a preliminary estimate of the potential structure that confines the particles to a grid structure in the plasma. This information is used to gain insight into the formation of the imposed grid pattern of the dust particles in the plasma.

  18. Quasi-discrete particle motion in an externally imposed, ordered structure in a dusty plasma at high magnetic field

    SciTech Connect

    Thomas, Edward Konopka, Uwe; Lynch, Brian; Adams, Stephen; LeBlanc, Spencer; Merlino, Robert L.; Rosenberg, Marlene

    2015-11-15

    Dusty plasmas have been studied in argon, radio frequency (rf) glow discharge plasmas at magnetic fields up to 2.5 T where the electrons and ions are strongly magnetized. Plasmas are generated between two parallel plate electrodes where the lower, powered electrode is solid and the upper electrode supports a dual mesh consisting of #24 brass and #30 aluminum wire cloth. In this experiment, we study the formation of imposed ordered structures and particle dynamics as a function of magnetic field. Through observations of trapped particles and the quasi-discrete (i.e., “hopping”) motion of particles between the trapping locations, it is possible to make a preliminary estimate of the potential structure that confines the particles to a grid structure in the plasma. This information is used to gain insight into the formation of the imposed grid pattern of the dust particles in the plasma.

  19. A Novel Hybrid Statistical Particle Swarm Optimization for Multimodal Functions and Frequency Control of Hybrid Wind-Solar System

    NASA Astrophysics Data System (ADS)

    Verma, Harish Kumar; Jain, Cheshta

    2016-09-01

    In this article, a hybrid algorithm of particle swarm optimization (PSO) with statistical parameter (HSPSO) is proposed. Basic PSO for shifted multimodal problems have low searching precision due to falling into a number of local minima. The proposed approach uses statistical characteristics to update the velocity of the particle to avoid local minima and help particles to search global optimum with improved convergence. The performance of the newly developed algorithm is verified using various standard multimodal, multivariable, shifted hybrid composition benchmark problems. Further, the comparative analysis of HSPSO with variants of PSO is tested to control frequency of hybrid renewable energy system which comprises solar system, wind system, diesel generator, aqua electrolyzer and ultra capacitor. A significant improvement in convergence characteristic of HSPSO algorithm over other variants of PSO is observed in solving benchmark optimization and renewable hybrid system problems.

  20. Templated Formation of Discrete RNA and DNA:RNA Hybrid G-Quadruplexes and Their Interactions with Targeting Ligands.

    PubMed

    Bonnat, Laureen; Dejeu, Jérôme; Bonnet, Hugues; Génnaro, Béatrice; Jarjayes, Olivier; Thomas, Fabrice; Lavergne, Thomas; Defrancq, Eric

    2016-02-24

    G-rich RNA and DNA oligonucleotides derived from the human telomeric sequence were assembled onto addressable cyclopeptide platforms through oxime ligations and copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions. The resulting conjugates were able to fold into highly stable RNA and DNA:RNA hybrid G-quadruplex (G4) architectures as demonstrated by UV, circular dichroism (CD), and NMR spectroscopic analysis. Whereas rationally designed parallel RNA and DNA:RNA hybrid G4 topologies could be obtained, we could not force the formation of an antiparallel RNA G4 structure, thus supporting the idea that this topology is strongly disfavored. The binding affinities of four representative G4 ligands toward the discrete RNA and DNA:RNA hybrid G4 topologies were compared to the one obtained with the corresponding DNA G4 structure. Surface plasmon resonance (SPR) binding analysis suggests that the accessibility to G4 recognition elements is different among the three structures and supports the idea that G4 ligands might be shaped to achieve structure selectivity in a biological context.

  1. Study of discrete-particle effects in a one-dimensional plasma simulation with the Krook type collision model

    SciTech Connect

    Lai, Po-Yen; Chen, Liu; Lin-Liu, Y. R.; Chen, Shih-Hung

    2015-09-15

    The thermal relaxation time of a one-dimensional plasma has been demonstrated to scale with N{sub D}{sup 2} due to discrete particle effects by collisionless particle-in-cell (PIC) simulations, where N{sub D} is the particle number in a Debye length. The N{sub D}{sup 2} scaling is consistent with the theoretical analysis based on the Balescu-Lenard-Landau kinetic equation. However, it was found that the thermal relaxation time is anomalously shortened to scale with N{sub D} while externally introducing the Krook type collision model in the one-dimensional electrostatic PIC simulation. In order to understand the discrete particle effects enhanced by the Krook type collision model, the superposition principle of dressed test particles was applied to derive the modified Balescu-Lenard-Landau kinetic equation. The theoretical results are shown to be in good agreement with the simulation results when the collisional effects dominate the plasma system.

  2. A discrete particle approach to simulate the combined effect of blast and sand impact loading of steel plates

    NASA Astrophysics Data System (ADS)

    Børvik, T.; Olovsson, L.; Hanssen, A. G.; Dharmasena, K. P.; Hansson, H.; Wadley, H. N. G.

    2011-05-01

    The structural response of a stainless steel plate subjected to the combined blast and sand impact loading from a buried charge has been investigated using a fully coupled approach in which a discrete particle method is used to determine the load due to the high explosive detonation products, the air shock and the sand, and a finite element method predicts the plate deflection. The discrete particle method is based on rigid, spherical particles that transfer forces between each other during collisions. This method, which is based on a Lagrangian formulation, has several advantages over coupled Lagrangian-Eulerian approaches as both advection errors and severe contact problems are avoided. The method has been validated against experimental tests where spherical 150 g C-4 charges were detonated at various stand-off distances from square, edge-clamped 3.4 mm thick AL-6XN stainless steel plates. The experiments were carried out for a bare charge, a charge enclosed in dry sand and a charge enclosed in fully saturated wet sand. The particle-based method is able to describe the physical interactions between the explosive reaction products and soil particles leading to a realistic prediction of the sand ejecta speed and momentum. Good quantitative agreement between the experimental and predicted deformation response of the plates is also obtained.

  3. Using the discrete dipole approximation and holographic microscopy to measure rotational dynamics of non-spherical colloidal particles

    NASA Astrophysics Data System (ADS)

    Wang, Anna; Dimiduk, Thomas G.; Fung, Jerome; Razavi, Sepideh; Kretzschmar, Ilona; Chaudhary, Kundan; Manoharan, Vinothan N.

    2014-10-01

    We present a new, high-speed technique to track the three-dimensional translation and rotation of non-spherical colloidal particles. We capture digital holograms of micrometer-scale silica rods and sub-micrometer-scale Janus particles freely diffusing in water, and then fit numerical scattering models based on the discrete dipole approximation to the measured holograms. This inverse-scattering approach allows us to extract the position and orientation of the particles as a function of time, along with static parameters including the size, shape, and refractive index. The best-fit sizes and refractive indices of both particles agree well with expected values. The technique is able to track the center of mass of the rod to a precision of 35 nm and its orientation to a precision of 1.5°, comparable to or better than the precision of other 3D diffusion measurements on non-spherical particles. Furthermore, the measured translational and rotational diffusion coefficients for the silica rods agree with hydrodynamic predictions for a spherocylinder to within 0.3%. We also show that although the Janus particles have only weak optical asymmetry, the technique can track their 2D translation and azimuthal rotation over a depth of field of several micrometers, yielding independent measurements of the effective hydrodynamic radius that agree to within 0.2%. The internal and external consistency of these measurements validate the technique. Because the discrete dipole approximation can model scattering from arbitrarily shaped particles, our technique could be used in a range of applications, including particle tracking, microrheology, and fundamental studies of colloidal self-assembly or microbial motion.

  4. Robustness properties of discrete time regulators, LOG regulators and hybrid systems

    NASA Technical Reports Server (NTRS)

    Stein, G.; Athans, M.

    1979-01-01

    Robustness properites of sample-data LQ regulators are derived which show that these regulators have fundamentally inferior uncertainty tolerances when compared to their continuous-time counterparts. Results are also presented in stability theory, multivariable frequency domain analysis, LQG robustness, and mathematical representations of hybrid systems.

  5. A hybrid mathematical model for controlling particle size, particle size distribution, and color properties of toner particles

    NASA Astrophysics Data System (ADS)

    Ataeefard, Maryam; Shadman, Alireza; Saeb, Mohammad Reza; Mohammadi, Yousef

    2016-08-01

    A mathematical modeling approach was proposed combining the capabilities of response surface methodology (RSM) and desirability function (DF) and implemented successfully in production of printing toner particles. Toner powders were systematically synthesized through suspension copolymerization process. Applying RSM, a series of experiments were designed and toner particles were prepared and the effects of monomer ratio, colorant and surfactant content on the particle size (PS), particle size distribution (PSD), thermal and colorimetric properties (∆ E) of the resulting toner were monitored and discussed. The second-order models corresponding to each target characteristic, i.e., PS, PSD, and ∆ E of different types of toner powders, were obtained by individual optimization to express variation of each property in terms of polymerization parameters. Applying statistical calculations, the best reduced models were identified to be fed in the second step of optimization. Since toners with appropriate PS, PSD, and CP were needed, we applied multi-objective optimization based on DF approach. The results show that exact tuning of toner properties is closely possible with the aid of hybrid mathematical model developed in this work. Noticeably, desirabilities are very close to 100 %.

  6. Investigation of discrete component chip mounting technology for hybrid microelectronic circuits

    NASA Technical Reports Server (NTRS)

    Caruso, S. V.; Honeycutt, J. O.

    1975-01-01

    The use of polymer adhesives for high reliability microcircuit applications is a radical deviation from past practices in electronic packaging. Bonding studies were performed using two gold-filled conductive adhesives, 10/90 tin/lead solder and Indalloy no. 7 solder. Various types of discrete components were mounted on ceramic substrates using both thick-film and thin-film metallization. Electrical and mechanical testing were performed on the samples before and after environmental exposure to MIL-STD-883 screening tests.

  7. Synthesis of Discrete Alkyl-Silica Hybrid Nanowires and Their Assembly into Nanostructured Superhydrophobic Membranes.

    PubMed

    Yi, Deliang; Xu, Chenglong; Tang, Ruidie; Zhang, Xuehua; Caruso, Frank; Wang, Yajun

    2016-07-11

    We report the synthesis of highly flexible and mechanically robust hybrid silica nanowires (NWs) which can be used as novel building blocks to construct superhydrophobic functional materials with three-dimensional macroporous networks. The hybrid silica NWs, with an average diameter of 80 nm and tunable length of up to 12 μm, are prepared by anisotropic deposition of the hydrolyzed tetraethylorthosilicate in water/n-pentanol emulsions. A mechanistic investigation reveals that the trimethoxy(octadecyl)silane introduced to the water-oil interface in the synthesis plays key roles in stabilizing the water droplets to sub-100 nm and also growing a layer of octadecyl groups on the NW surface. This work opens a solution-based route for the one-pot preparation of monodisperse, hydrophobic silica NWs and represents an important step toward the bottom-up construction of 3D superhydrophobic materials and macroporous membranes. PMID:27278242

  8. Synthesis of Discrete Alkyl-Silica Hybrid Nanowires and Their Assembly into Nanostructured Superhydrophobic Membranes.

    PubMed

    Yi, Deliang; Xu, Chenglong; Tang, Ruidie; Zhang, Xuehua; Caruso, Frank; Wang, Yajun

    2016-07-11

    We report the synthesis of highly flexible and mechanically robust hybrid silica nanowires (NWs) which can be used as novel building blocks to construct superhydrophobic functional materials with three-dimensional macroporous networks. The hybrid silica NWs, with an average diameter of 80 nm and tunable length of up to 12 μm, are prepared by anisotropic deposition of the hydrolyzed tetraethylorthosilicate in water/n-pentanol emulsions. A mechanistic investigation reveals that the trimethoxy(octadecyl)silane introduced to the water-oil interface in the synthesis plays key roles in stabilizing the water droplets to sub-100 nm and also growing a layer of octadecyl groups on the NW surface. This work opens a solution-based route for the one-pot preparation of monodisperse, hydrophobic silica NWs and represents an important step toward the bottom-up construction of 3D superhydrophobic materials and macroporous membranes.

  9. Influence of particle shape and sample width on uniaxial compression of assembly of prolate spheroids examined by discrete element method

    NASA Astrophysics Data System (ADS)

    Parafiniuk, Piotr; Molenda, Marek; Horabik, Józef

    2014-12-01

    We use numerical simulations based on the discrete element method (DEM) to study the response of a cuboidal assembly of spherical (diameter d) or spheroidal particles to uniaxial compression. This study examines the influences of slight deviations from the spherical shape of particles or of the thickness of cuboidal samples on the packing and mechanical characteristics of the assembly. The spheroidal particles were fabricated by the multisphere method. Eight different particle shapes were considered, each with the same volume and with aspect ratios α from 1.0 to 2.5. The final vertical height and larger horizontal depth of the cuboidal deposit were 15d, whereas the thickness ranged from 1.025d to 10d. Upon increasing the assembly thickness or deviating from a spherical shape, numerical examinations by the DEM revealed clear differences in the packing structure and uniaxial compression of assemblies of spheroidal particles. The departure from a spherical shape results in intense changes in contact network, which is manifested as changes in the volume fraction, mean number of contacts per particle, and ordering of the deposits. For the more elongated particles, the pressure ratio as a function of spheroid aspect ratio reached nearly constant values regardless of the sample thickness.

  10. Polystyrene-Core-Silica-Shell Hybrid Particles Containing Gold and Magnetic Nanoparticles.

    PubMed

    Tian, Jia; Vana, Philipp

    2016-02-18

    Polystyrene-core-silica-shell hybrid particles were synthesized by combining the self-assembly of nanoparticles and the polymer with a silica coating strategy. The core-shell hybrid particles are composed of gold-nanoparticle-decorated polystyrene (PS-AuNP) colloids as the core and silica particles as the shell. PS-AuNP colloids were generated by the self-assembly of the PS-grafted AuNPs. The silica coating improved the thermal stability and dispersibility of the AuNPs. By removing the "free" PS of the core, hollow particles with a hydrophobic cage having a AuNP corona and an inert silica shell were obtained. Also, Fe3O4 nanoparticles were encapsulated in the core, which resulted in magnetic core-shell hybrid particles by the same strategy. These particles have potential applications in biomolecular separation and high-temperature catalysis and as nanoreactors.

  11. A hybridGaussian-discrete variable representation approach to molecular continuum processes II: application to photoionization of diatomic Li2+

    SciTech Connect

    Rescigno, Thomas N; Yip, Frank L.; McCurdy, C. William; Rescigno, Thomas N.

    2008-08-01

    We describe an approach for studying molecular photoionization with a hybrid basis that combines the functionality of analytic basis sets to represent electronic coordinates near the nuclei of a molecule with numerically-defined grid-based functions. We discuss the evaluation of the various classes of two-electron integrals that occur in a hybrid basis consisting of Gaussian type orbitals (GTOs) and discrete variable representation (DVR) functions. This combined basis is applied to calculate single photoionization cross sections for molecular Li_2+, which has a large equilibrium bond distance (R=5.86a_0). The highly non-spherical nature of Li_2+ molecules causes higher angular momentum components to contribute significantly to the cross section even at low photoelectron energies, resulting in angular distributions that appear to be f-wave dominated near the photoionization threshold. At higher energies, where the de Broglie wavelength of the photoelectron becomes comparable with the bond distance, interference effects appear in the photoionization cross section. These interference phenomena appear at much lower energies than would be expected for diatomic targets with shorter internuclear separations.

  12. Material and interaction properties of selected grains and oilseeds for modeling discrete particles

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Experimental investigations of grain flow can be expensive and time-consuming, but computer simulations can reduce the large effort required to evaluate the flow of grain in handling operations. Published data on material and interaction properties of selected grains and oilseeds relevant to Discret...

  13. Hybrid Particle Code Simulations of Mars: The Role of Crustal Magnetic Fields in Ionospheric Escape

    NASA Astrophysics Data System (ADS)

    Brecht, S. H.; Ledvina, S. A.

    2014-07-01

    Using the three dimensional hybrid particle code, the role of neutral winds in the escape of ionospheric ions is investigated. The results in terms of loss rates and interaction around the crustal magnetic fields will be presented.

  14. Hybrid Discrete Wavelet Transform and Gabor Filter Banks Processing for Features Extraction from Biomedical Images

    PubMed Central

    Lahmiri, Salim; Boukadoum, Mounir

    2013-01-01

    A new methodology for automatic feature extraction from biomedical images and subsequent classification is presented. The approach exploits the spatial orientation of high-frequency textural features of the processed image as determined by a two-step process. First, the two-dimensional discrete wavelet transform (DWT) is applied to obtain the HH high-frequency subband image. Then, a Gabor filter bank is applied to the latter at different frequencies and spatial orientations to obtain new Gabor-filtered image whose entropy and uniformity are computed. Finally, the obtained statistics are fed to a support vector machine (SVM) binary classifier. The approach was validated on mammograms, retina, and brain magnetic resonance (MR) images. The obtained classification accuracies show better performance in comparison to common approaches that use only the DWT or Gabor filter banks for feature extraction. PMID:27006906

  15. A hybrid mortar virtual element method for discrete fracture network simulations

    NASA Astrophysics Data System (ADS)

    Benedetto, Matías Fernando; Berrone, Stefano; Borio, Andrea; Pieraccini, Sandra; Scialò, Stefano

    2016-02-01

    The most challenging issue in performing underground flow simulations in Discrete Fracture Networks (DFN) is to effectively tackle the geometrical difficulties of the problem. In this work we put forward a new application of the Virtual Element Method combined with the Mortar method for domain decomposition: we exploit the flexibility of the VEM in handling polygonal meshes in order to easily construct meshes conforming to the traces on each fracture, and we resort to the mortar approach in order to "weakly" impose continuity of the solution on intersecting fractures. The resulting method replaces the need for matching grids between fractures, so that the meshing process can be performed independently for each fracture. Numerical results show optimal convergence and robustness in handling very complex geometries.

  16. Numerical Simulation of P-Wave Propagation in Rock Mass with Granular Material-Filled Fractures Using Hybrid Continuum-Discrete Element Method

    NASA Astrophysics Data System (ADS)

    Gui, Y. L.; Zhao, Z. Y.; Zhou, H. Y.; Wu, W.

    2016-10-01

    In this paper, a cohesive fracture model is applied to model P-wave propagation through fractured rock mass using hybrid continuum-discrete element method, i.e. Universal Distinct Element Code (UDEC). First, a cohesive fracture model together with the background of UDEC is presented. The cohesive fracture model considers progressive failure of rock fracture rather than an abrupt damage through simultaneously taking into account the elastic, plastic and damage mechanisms as well as a modified failure function. Then, a series of laboratory tests from the literature on P-wave propagation through rock mass containing single fracture and two parallel fractures are introduced and the numerical models used to simulate these laboratory tests are described. After that, all the laboratory tests are simulated and presented. The results show that the proposed model, particularly the cohesive fracture model, can capture very well the wave propagation characteristics in rock mass with non-welded and welded fractures with and without filling materials. In the meantime, in order to identify the significance of fracture on wave propagation, filling materials with different particle sizes and the fracture thickness are discussed. Both factors are found to be crucial for wave attenuation. The simulations also show that the frequency of transmission wave is lowered after propagating through fractures. In addition, the developed numerical scheme is applied to two-dimensional wave propagation in the rock mass.

  17. Computationally efficient approach for solving time dependent diffusion equation with discrete temporal convolution applied to granular particles of battery electrodes

    NASA Astrophysics Data System (ADS)

    Senegačnik, Jure; Tavčar, Gregor; Katrašnik, Tomaž

    2015-03-01

    The paper presents a computationally efficient method for solving the time dependent diffusion equation in a granule of the Li-ion battery's granular solid electrode. The method, called Discrete Temporal Convolution method (DTC), is based on a discrete temporal convolution of the analytical solution of the step function boundary value problem. This approach enables modelling concentration distribution in the granular particles for arbitrary time dependent exchange fluxes that do not need to be known a priori. It is demonstrated in the paper that the proposed method features faster computational times than finite volume/difference methods and Padé approximation at the same accuracy of the results. It is also demonstrated that all three addressed methods feature higher accuracy compared to the quasi-steady polynomial approaches when applied to simulate the current densities variations typical for mobile/automotive applications. The proposed approach can thus be considered as one of the key innovative methods enabling real-time capability of the multi particle electrochemical battery models featuring spatial and temporal resolved particle concentration profiles.

  18. Isolation of Discrete Nanoparticle-DNA Conjugates for Plasmonic Applications

    SciTech Connect

    Alivisatos, Paul; Claridge, Shelley A.; Liang, Huiyang W.; Basu, Sourav Roger; Frechet, Jean M.J.; Alivisatos, A. Paul

    2008-04-11

    Discrete DNA-gold nanoparticle conjugates with DNA lengths as short as 15 bases for both 5 nm and 20 nm gold particles have been purified by anion-exchange HPLC. Conjugates comprising short DNA (<40 bases) and large gold particles (>_ 20 nm) are difficult to purify by other means, and are potential substrates for plasmon coupling experiments. Conjugate purity is demonstrated by hybridizing complementary conjugates to form discrete structures, which are visualized by TEM.

  19. Hybrid pathwise sensitivity methods for discrete stochastic models of chemical reaction systems

    SciTech Connect

    Wolf, Elizabeth Skubak; Anderson, David F.

    2015-01-21

    Stochastic models are often used to help understand the behavior of intracellular biochemical processes. The most common such models are continuous time Markov chains (CTMCs). Parametric sensitivities, which are derivatives of expectations of model output quantities with respect to model parameters, are useful in this setting for a variety of applications. In this paper, we introduce a class of hybrid pathwise differentiation methods for the numerical estimation of parametric sensitivities. The new hybrid methods combine elements from the three main classes of procedures for sensitivity estimation and have a number of desirable qualities. First, the new methods are unbiased for a broad class of problems. Second, the methods are applicable to nearly any physically relevant biochemical CTMC model. Third, and as we demonstrate on several numerical examples, the new methods are quite efficient, particularly if one wishes to estimate the full gradient of parametric sensitivities. The methods are rather intuitive and utilize the multilevel Monte Carlo philosophy of splitting an expectation into separate parts and handling each in an efficient manner.

  20. Physicochemical characterization of discrete weapons grade plutonium metal particles originating from the 1960 BOMARC incident

    NASA Astrophysics Data System (ADS)

    Bowen, James M.

    The goal of this research was to investigate the physicochemical properties of weapons grade plutonium particles originating from the 1960 BOMARC incident for the purpose of predicting their fate in the environment and to address radiation protection and nuclear security concerns. Methods were developed to locate and isolate the particles in order to characterize them. Physical, chemical, and radiological characterization was performed using a variety of techniques. And finally, the particles were subjected to a sequential extraction procedure, a series of increasingly aggressive reagents, to simulate an accelerated environmental exposure. A link between the morphology of the particles and their partitioning amongst environmental mechanisms was established.

  1. Exponential characteristic spatial quadrature for discrete ordinates neutral particle transport in two-dimensional cartesian coordinates. Doctoral thesis

    SciTech Connect

    Minor, B.M.

    1993-09-01

    The exponential characteristic spatial quadrature for discrete ordinates neutral particle transport with rectangular cells is developed. Numerical problems arising in the derivation required the development of exponential moment functions. These functions are used to remove indeterminant forms which can cause catastrophic cancellations. The EC method is positive and nonlinear. It conserves particles and satisfies first moment balance. Comparisons of the EC method's performance to other methods in optically thin and thick spatial cells were performed. For optically thin cells, the EC method was shown to converge to the correct answer, with third order truncation error in the thin cell limit. In deep penetration problems, the EC method attained its highest computational efficiencies compared to the other methods. For all the deep penetration problems examined, the number of spatial cells required by the EC method to attain a desired accuracy was less than the other methods.... Mathematics functions, Nuclear radiation, Nuclear engineering, Radiation attenuation, Radiation shielding, Transport theory, Radiation transport.

  2. Controlled isotropic or anisotropic nanoscale growth of coordination polymers: formation of hybrid coordination polymer particles.

    PubMed

    Lee, Hee Jung; Cho, Yea Jin; Cho, Won; Oh, Moonhyun

    2013-01-22

    The ability to fabricate multicompositional hybrid materials in a precise and controlled manner is one of the primary goals of modern materials science research. In addition, an understanding of the phenomena associated with the systematic growth of one material on another can facilitate the evolution of multifunctional hybrid materials. Here, we demonstrate precise manipulation of the isotropic and/or anisotropic nanoscale growth of various coordination polymers (CPs) to obtain heterocompositional hybrid coordination polymer particles. Chemical composition analyses conducted at every growth step reveal the formation of accurately assembled hybrid nanoscale CPs, and microscopy images are used to examine the morphology of the particles and visualize the hybrid structures. The dissimilar growth behavior, that is, growth in an isotropic or anisotropic fashion, is found to be dependent on the size of the metal ions involved within the CPs.

  3. Sub-pixel flood inundation mapping from multispectral remotely sensed images based on discrete particle swarm optimization

    NASA Astrophysics Data System (ADS)

    Li, Linyi; Chen, Yun; Yu, Xin; Liu, Rui; Huang, Chang

    2015-03-01

    The study of flood inundation is significant to human life and social economy. Remote sensing technology has provided an effective way to study the spatial and temporal characteristics of inundation. Remotely sensed images with high temporal resolutions are widely used in mapping inundation. However, mixed pixels do exist due to their relatively low spatial resolutions. One of the most popular approaches to resolve this issue is sub-pixel mapping. In this paper, a novel discrete particle swarm optimization (DPSO) based sub-pixel flood inundation mapping (DPSO-SFIM) method is proposed to achieve an improved accuracy in mapping inundation at a sub-pixel scale. The evaluation criterion for sub-pixel inundation mapping is formulated. The DPSO-SFIM algorithm is developed, including particle discrete encoding, fitness function designing and swarm search strategy. The accuracy of DPSO-SFIM in mapping inundation at a sub-pixel scale was evaluated using Landsat ETM + images from study areas in Australia and China. The results show that DPSO-SFIM consistently outperformed the four traditional SFIM methods in these study areas. A sensitivity analysis of DPSO-SFIM was also carried out to evaluate its performances. It is hoped that the results of this study will enhance the application of medium-low spatial resolution images in inundation detection and mapping, and thereby support the ecological and environmental studies of river basins.

  4. Particle-laden interfaces: direct calculation of interfacial stress from a discrete particle simulation of a pendant drop

    NASA Astrophysics Data System (ADS)

    Gu, Chuan; Botto, Lorenzo

    2015-11-01

    The adsorption of solid particles to fluid interfaces is exploited in several multiphase flow technologies, and plays a fundamental role in the dynamics of particle-laden drops. A fundamental question is how the particles modify the effective mechanical properties of the interface. Using a fast Eulerian-Lagrangian model for interfacial colloids, we have simulated a pendant drop whose surface is covered with spherical particles having short-range repulsion. The interface curvature induces non-uniform and anisotropic interfacial stresses, which we calculate by an interfacial extension of the Irving-Kirkwood formula. The isotropic component of this stress, related to the effective surface tension, is in good agreement with that calculated by fitting the drop shape to the Young-Laplace equation. The anisotropic component, related to the interfacial shear elasticity, is highly non uniform: small at the drop apex, significant along the drop sides. The reduction in surface tension can be substantial even below maximum surface packing. We illustrate this point by simulating phase-coarsening of a two-phase mixture in which the presence of interfacial particles ``freezes'' the coarsening process, for surface coverage well below maximum packing This work is supported by the EU through the Marie Curie Grant FLOWMAT (618335).

  5. Heat generation in an elastic binder system with embedded discrete energetic particles due to high-frequency, periodic mechanical excitation

    NASA Astrophysics Data System (ADS)

    Mares, J. O.; Miller, J. K.; Gunduz, I. E.; Rhoads, J. F.; Son, S. F.

    2014-11-01

    High-frequency mechanical excitation can induce heating within energetic materials and may lead to advances in explosives detection and defeat. In order to examine the nature of this mechanically induced heating, samples of an elastic binder (Sylgard 184) were embedded with inert and energetic particles placed in a fixed spatial pattern and were subsequently excited with an ultrasonic transducer at discrete frequencies from 100 kHz to 20 MHz. The temperature and velocity responses of the sample surfaces suggest that heating due to frictional effects occurred near the particles at excitation frequencies near the transducer resonance of 215 kHz. An analytical solution involving a heat point source was used to estimate heating rates and temperatures at the particle locations in this frequency region. Heating located near the sample surface at frequencies near and above 1 MHz was attributed to viscoelastic effects related to the surface motion of the samples. At elevated excitation parameters near the transducer resonance frequency, embedded particles of ammonium perchlorate and cyclotetramethylene-tetranitramine were driven to chemical decomposition.

  6. Hybrid Upwind Discretization for the Implicit Simulation of Three-Phase Coupled Flow and Transport with Gravity

    NASA Astrophysics Data System (ADS)

    Hamon, F. P.; Mallison, B.; Tchelepi, H.

    2015-12-01

    The systems of algebraic equations arising from implicit (backward-Euler) finite-volume discretization of the conservation laws governing multiphase flow in porous media are quite challenging for nonlinear solvers. In the presence of counter-current flow due to buoyancy, the coupling between flow (pressure) and transport (saturations) is often the cause of nonlinear problems when single-point Phase-Potential Upwinding (PPU) is used. To overcome such convergence problems in practice, the time step is reduced and Newton's method is restarted from the solution at the previous converged time step. Here, we generalize the work of Lee, Efendiev and Tchelepi [Advances in Water Resources, 2015] to propose an Implicit Hybrid Upwinding (IHU) scheme for coupled flow and transport. In the pure transport problem, we show that the numerical flux obtained with IHU is differentiable, monotone and consistent for two and three-phase flow. For coupled flow and transport, we prove saturation physical bounds as well as the existence of a solution to our scheme. Challenging two- and three-phase heterogeneous multi-dimensional numerical tests confirm that the new scheme is non-oscillatory and convergent, and illustrate the superior convergence rate of our IHU-based Newton solver for large time steps.

  7. Computational analysis of electrical conduction in hybrid nanomaterials with embedded non-penetrating conductive particles

    NASA Astrophysics Data System (ADS)

    Cai, Jizhe; Naraghi, Mohammad

    2016-08-01

    In this work, a comprehensive multi-resolution two-dimensional (2D) resistor network model is proposed to analyze the electrical conductivity of hybrid nanomaterials made of insulating matrix with conductive particles such as CNT reinforced nanocomposites and thick film resistors. Unlike existing approaches, our model takes into account the impenetrability of the particles and their random placement within the matrix. Moreover, our model presents a detailed description of intra-particle conductivity via finite element analysis, which to the authors’ best knowledge has not been addressed before. The inter-particle conductivity is assumed to be primarily due to electron tunneling. The model is then used to predict the electrical conductivity of electrospun carbon nanofibers as a function of microstructural parameters such as turbostratic domain alignment and aspect ratio. To simulate the microstructure of single CNF, randomly positioned nucleation sites were seeded and grown as turbostratic particles with anisotropic growth rates. Particle growth was in steps and growth of each particle in each direction was stopped upon contact with other particles. The study points to the significant contribution of both intra-particle and inter-particle conductivity to the overall conductivity of hybrid composites. Influence of particle alignment and anisotropic growth rate ratio on electrical conductivity is also discussed. The results show that partial alignment in contrast to complete alignment can result in maximum electrical conductivity of whole CNF. High degrees of alignment can adversely affect conductivity by lowering the probability of the formation of a conductive path. The results demonstrate approaches to enhance electrical conductivity of hybrid materials through controlling their microstructure which is applicable not only to carbon nanofibers, but also many other types of hybrid composites such as thick film resistors.

  8. Two-dimensional quasineutral description of particles and fields above discrete auroral arcs

    NASA Technical Reports Server (NTRS)

    Newman, A. L.; Chiu, Y. T.; Cornwall, J. M.

    1985-01-01

    Stationary hot and cool particle distributions in the auroral magnetosphere are modelled using adiabatic assumptions of particle motion in the presence of broad-scale electrostatic potential structure. The study has identified geometrical restrictions on the type of broadscale potential structure which can be supported by a multispecies plasma having specified sources and energies. Without energization of cool thermal ionospheric electrons, a substantial parallel potential drop cannot be supported down to altitudes of 2000 km or less. Observed upward-directed field-aligned currents must be closed by return currents along field lines which support little net potential drop. In such regions the plasma density appears significantly enhanced. Model details agree well with recent broad-scale implications of satellite observations.

  9. Quantum efficiency of colloidal suspensions containing quantum dot/silica hybrid particles

    NASA Astrophysics Data System (ADS)

    Jeon, Hyungjoon; Yoon, Cheolsang; Lee, Sooho; Lee, Doh C.; Shin, Kyusoon; Lee, Kangtaek

    2016-10-01

    We have investigated the fluorescence properties of colloidal suspensions conntaining quantum dot (QD)/silica hybrid particles. First, we synthesized QD/silica hybrid particles with silica-QD-silica (SQS) core-shell-shell geometry, and monitored the quantum efficiencies of their suspensions at various particle concentrations. We found that the quantum efficiency (QE) of SQS particles in deionized (DI) water was much lower than that of the QDs even at low particle concentration, mainly due to the light scattering of emitted photons at the silica/water interface, followed by reabsorption by QDs. As the concentration of SQS particles was increased, both light scattering and reabsorption by QDs became more important, which further reduced the QE. Refractive index-matched solvent, however, reduced light scattering, yielding greater QE than DI water. Next, we induced aggregation of SQS particles, and found that QE increased as particles aggregated in DI water because of reduced light scattering and reabsorption, whereas it remained almost constant in the refractive index-matched solvent. Finally, we studied aggregation of highly concentrated silica particle suspensions containing a low concentration of SQS particles, and found that QE increased with aggregation because light scattering and reabsorption were reduced.

  10. Quantum efficiency of colloidal suspensions containing quantum dot/silica hybrid particles.

    PubMed

    Jeon, Hyungjoon; Yoon, Cheolsang; Lee, Sooho; Lee, Doh C; Shin, Kyusoon; Lee, Kangtaek

    2016-10-28

    We have investigated the fluorescence properties of colloidal suspensions conntaining quantum dot (QD)/silica hybrid particles. First, we synthesized QD/silica hybrid particles with silica-QD-silica (SQS) core-shell-shell geometry, and monitored the quantum efficiencies of their suspensions at various particle concentrations. We found that the quantum efficiency (QE) of SQS particles in deionized (DI) water was much lower than that of the QDs even at low particle concentration, mainly due to the light scattering of emitted photons at the silica/water interface, followed by reabsorption by QDs. As the concentration of SQS particles was increased, both light scattering and reabsorption by QDs became more important, which further reduced the QE. Refractive index-matched solvent, however, reduced light scattering, yielding greater QE than DI water. Next, we induced aggregation of SQS particles, and found that QE increased as particles aggregated in DI water because of reduced light scattering and reabsorption, whereas it remained almost constant in the refractive index-matched solvent. Finally, we studied aggregation of highly concentrated silica particle suspensions containing a low concentration of SQS particles, and found that QE increased with aggregation because light scattering and reabsorption were reduced. PMID:27658534

  11. Quantum efficiency of colloidal suspensions containing quantum dot/silica hybrid particles.

    PubMed

    Jeon, Hyungjoon; Yoon, Cheolsang; Lee, Sooho; Lee, Doh C; Shin, Kyusoon; Lee, Kangtaek

    2016-10-28

    We have investigated the fluorescence properties of colloidal suspensions conntaining quantum dot (QD)/silica hybrid particles. First, we synthesized QD/silica hybrid particles with silica-QD-silica (SQS) core-shell-shell geometry, and monitored the quantum efficiencies of their suspensions at various particle concentrations. We found that the quantum efficiency (QE) of SQS particles in deionized (DI) water was much lower than that of the QDs even at low particle concentration, mainly due to the light scattering of emitted photons at the silica/water interface, followed by reabsorption by QDs. As the concentration of SQS particles was increased, both light scattering and reabsorption by QDs became more important, which further reduced the QE. Refractive index-matched solvent, however, reduced light scattering, yielding greater QE than DI water. Next, we induced aggregation of SQS particles, and found that QE increased as particles aggregated in DI water because of reduced light scattering and reabsorption, whereas it remained almost constant in the refractive index-matched solvent. Finally, we studied aggregation of highly concentrated silica particle suspensions containing a low concentration of SQS particles, and found that QE increased with aggregation because light scattering and reabsorption were reduced.

  12. Global Hybrid Simulations of Energetic Particle-driven Modes in Toroidal Plasmas

    SciTech Connect

    G.Y. Fu; J. Breslau; E. Fredrickson; W. Park; H.R. Strauss

    2004-12-14

    Global hybrid simulations of energetic particle-driven MHD modes have been carried out for tokamaks and spherical tokamaks using the hybrid code M3D. The numerical results for the National Spherical Tokamak Experiments (NSTX) show that Toroidal Alfven Eigenmodes are excited by beam ions with their frequencies consistent with the experimental observations. Nonlinear simulations indicate that the n=2 mode frequency chirps down as the mode moves out radially. For ITER, it is shown that the alpha-particle effects are strongly stabilizing for internal kink mode when central safety factor q(0) is sufficiently close to unity. However, the elongation of ITER plasma shape reduces the stabilization significantly.

  13. Hybrid Finite-Discrete Element Simulation of the EDZ Formation and Mechanical Sealing Process Around a Microtunnel in Opalinus Clay

    NASA Astrophysics Data System (ADS)

    Lisjak, Andrea; Tatone, Bryan S. A.; Mahabadi, Omid K.; Grasselli, Giovanni; Marschall, Paul; Lanyon, George W.; Vaissière, Rémi de la; Shao, Hua; Leung, Helen; Nussbaum, Christophe

    2016-05-01

    The analysis and prediction of the rock mass disturbance around underground excavations are critical components of the performance and safety assessment of deep geological repositories for nuclear waste. In the short term, an excavation damaged zone (EDZ) tends to develop due to the redistribution of stresses around the underground openings. The EDZ is associated with an increase in hydraulic conductivity of several orders of magnitude. In argillaceous rocks, sealing mechanisms ultimately lead to a partial reduction in the effective hydraulic conductivity of the EDZ with time. The goal of this study is to strengthen the understanding of the phenomena involved in the EDZ formation and sealing in Opalinus Clay, an indurated claystone currently being assessed as a host rock for a geological repository in Switzerland. To achieve this goal, hybrid finite-discrete element method (FDEM) simulations are performed. With its explicit consideration of fracturing processes, FDEM modeling is applied to the HG-A experiment, an in situ test carried out at the Mont Terri underground rock laboratory to investigate the hydro-mechanical response of a backfilled and sealed microtunnel. A quantitative simulation of the EDZ formation process around the microtunnel is first carried out, and the numerical results are compared with field observations. Then, the re-compression of the EDZ under the effect of a purely mechanical loading, capturing the increase of swelling pressure from the backfill onto the rock, is considered. The simulation results highlight distinctive rock failure kinematics due to the bedded structure of the rock mass. Also, fracture termination is simulated at the intersection with a pre-existing discontinuity, representing a fault plane oblique to the bedding orientation. Simulation of the EDZ re-compression indicates an overall reduction of the total fracture area as a function of the applied pressure, with locations of ineffective sealing associated with self

  14. Mechanism of Methylene Blue adsorption on hybrid laponite-multi-walled carbon nanotube particles.

    PubMed

    Manilo, Maryna; Lebovka, Nikolai; Barany, Sandor

    2016-04-01

    The kinetics of adsorption and parameters of equilibrium adsorption of Methylene Blue (MB) on hybrid laponite-multi-walled carbon nanotube (NT) particles in aqueous suspensions were determined. The laponite platelets were used in order to facilitate disaggregation of NTs in aqueous suspensions and enhance the adsorption capacity of hybrid particles for MB. Experiments were performed at room temperature (298 K), and the laponite/NT ratio (Xl) was varied in the range of 0-0.5. For elucidation of the mechanism of MB adsorption on hybrid particles, the electrical conductivity of the system as well as the electrokinetic potential of laponite-NT hybrid particles were measured. Three different stages in the kinetics of adsorption of MB on the surface of NTs or hybrid laponite-NT particles were discovered to be a fast initial stage I (adsorption time t=0-10 min), a slower intermediate stage II (up to t=120 min) and a long-lasting final stage III (up to t=24hr). The presence of these stages was explained accounting for different types of interactions between MB and adsorbent particles, as well as for the changes in the structure of aggregates of NT particles and the long-range processes of restructuring of laponite platelets on the surface of NTs. The analysis of experimental data on specific surface area versus the value of Xl evidenced in favor of the model with linear contacts between rigid laponite platelets and NTs. It was also concluded that electrostatic interactions control the first stage of adsorption at low MB concentrations.

  15. Hybrid Particle-Continuum Methods for Nonequilibrium Gas and Plasma Flows

    SciTech Connect

    Boyd, Iain D.

    2011-05-20

    Two different hybrid particle-continuum methods are described for simulation of nonequilibrium gas and plasma dynamics. The first technique, used for nonequilibrium hypersonic gas flows, uses either a continuum description or a particle method throughout a flow domain based on local conditions. This technique is successful in reproducing the results of full particle simulations at a small fraction of the cost. The second method uses a continuum model of the electrons combined with a particle description of the ions and atoms for simulating plasma jets. The physical accuracy of the method is assessed through comparisons with plasma plume measurements obtained in space. These examples illustrate that the complex physical phenomena associated with nonequilibrium conditions can be simulated with physical accuracy and numerical efficiency using such hybrid approaches.

  16. Particle method for upscaling transport with retention and in-growth in three-dimensional discrete fracture networks

    NASA Astrophysics Data System (ADS)

    Cvetkovic, V.; Frampton, A.; Painter, S.; Selroos, J.

    2008-12-01

    An important challenge in subsurface hydrology is predictive modeling of tracer transport in sparsely fractured rock. A particular issue relevant for applications is how to accurately account for retention processes that are due to exchange (diffusion-sorption) of tracers between mobile fluid in fractures and immobile fluid in the rock matrix. Typically, tracers are subject to decay processes which may involve chains and in-growth (e.g., for radionuclides and some classes of hydrocarbons). Recently, a comprehensive particle-based methodology for upscaling transport with emphasis on tracer retention has been presented and applied to stochastic 2D discrete fracture networks (Frampton and Cvetkovic 2007, WRR, 43, W10429). Furthermore, a time domain random walk method has also recently been presented that effectively accounts for different exchange mechanisms and in-growth (Painter et al. 2008, WRR, 44, W01406). Now we present further advances in coupling these novel methodologies for solving radionuclide transport, and apply them to realistic 3D fracture networks, based on comprehensive data sets obtained from site characterization of the Laxemar area in south-east Sweden. Site measurements have revealed at least five fracture sets based on statistically significant orientation data, exhibiting power-law behaviour for fracture size and inferred transmissivity distributions. A few equally probable DFN realizations are generated based on these interpretations of the field data, in which advective fluid flow is solved using boundary conditions that mimic natural conditions. Thereafter, many particles are injected and tracked through the system, providing first- passage distributions of particle residence time and of the transport resistance parameter (quantifying the hydrodynamic control of retention). These distributions are then used as a basis for implementing the particle time-domain random walk model for radionuclide transport with retention and in-growth. Also, an

  17. Hybrid sensor for metal grade measurement of a falling stream of solid waste particles

    SciTech Connect

    Abdur Rahman, Md. Bakker, M.C.M.

    2012-07-15

    Highlights: Black-Right-Pointing-Pointer A new sensor system is developed for metal grade measurement of falling bottom ash particles. Black-Right-Pointing-Pointer The system is hybrid, consisting of an optical and an electromagnetic sensor. Black-Right-Pointing-Pointer Grade of ECS concentrated bottom ash in 1-6 mm sieve size accurately measured up to 143 p/s feed rate. Black-Right-Pointing-Pointer Accuracy reached was 2.4% with respect to manual analysis. Black-Right-Pointing-Pointer Measures for elimination of both stationary and stochastic errors are discussed. - Abstract: A hybrid sensor system for accurate detection of the metal grade of a stream of falling solid waste particles is investigated and experimentally verified. The system holds an infrared and an electromagnetic unit around a central tube and counts all the particles and only the metal particles, respectively. The count ratio together with the measured average particle mass ratio (k) of non-metal and metal particles is sufficient for calculation of grade. The performance of the system is accurately verified using synthetic mixtures of sand and metal particles. Towards an application a case study is performed using municipal solid waste incineration bottom ash in size fractions 1-6 mm, which presents a major challenge for nonferrous metal recovery. The particle count ratio was inherently accurate for particle feed rates up to 13 per second. The average value and spread of k for bottom ash was determined as 0.49 {+-} 0.07 and used to calculate grade within 2.4% from the manually analysed grade. At higher feed rates the sensors start missing particles which fall simultaneously through the central tube, but the hybrid system still counted highly repeatable. This allowed for implementation of a count correction ratio to eliminate the stationary error. In combination with averaging in measurement intervals for suppression of stochastic variations the hybrid system regained its accuracy for particle feed

  18. Strength Pareto particle swarm optimization and hybrid EA-PSO for multi-objective optimization.

    PubMed

    Elhossini, Ahmed; Areibi, Shawki; Dony, Robert

    2010-01-01

    This paper proposes an efficient particle swarm optimization (PSO) technique that can handle multi-objective optimization problems. It is based on the strength Pareto approach originally used in evolutionary algorithms (EA). The proposed modified particle swarm algorithm is used to build three hybrid EA-PSO algorithms to solve different multi-objective optimization problems. This algorithm and its hybrid forms are tested using seven benchmarks from the literature and the results are compared to the strength Pareto evolutionary algorithm (SPEA2) and a competitive multi-objective PSO using several metrics. The proposed algorithm shows a slower convergence, compared to the other algorithms, but requires less CPU time. Combining PSO and evolutionary algorithms leads to superior hybrid algorithms that outperform SPEA2, the competitive multi-objective PSO (MO-PSO), and the proposed strength Pareto PSO based on different metrics.

  19. Bioactive Hybrid Particles from Poly(D,L-lactide-co-glycolide) Nanoparticle Stabilized Lipid Droplets.

    PubMed

    Joyce, Paul; Whitby, Catherine P; Prestidge, Clive A

    2015-08-12

    Biodegradable and bioactive hybrid particles composed of poly(D,L-lactide-co-glycolide) (PLGA) nanoparticles and medium-chain triglycerides were prepared by spray drying lipid-in-water emulsions stabilized by PLGA nanoparticles, to form PLGA-lipid hybrid (PLH) microparticles approximately 5 μm in mean diameter. The nanoparticle stabilizer was varied and mannitol was also incorporated during the preparation to investigate the effect of stabilizer charge and cryoprotectant content on the particle microstructure. An in vitro lipolysis model was used to demonstrate the particles' bioactivity by manipulating the digestion kinetics of encapsulated lipid by pancreatic lipase in simulated gastrointestinal fluid. Lipid digestion kinetics were enhanced in PLH and PLGA-lipid-mannitol hybrid (PLMH) microparticles for both stabilizers, compared to a coarse emulsion, in biorelevant media. An optimal digestion rate was observed for the negatively charged PLMH system, evidenced by a 2-fold increase in the pseudo-first-order rate constant compared to a coarse emulsion. Improved microparticle redispersion, probed by dual dye confocal fluorescence microscopy, increased the available surface area of lipid for lipase adsorption, enhancing digestion kinetics. Thereby, lipase action was controlled in hybrid microparticles by altering the surface charge and carbohydrate content. Our results demonstrate that bioactive microparticles composed of versatile and biodegradable polymeric particles and oil droplets have great potential for use in smart food and nutrient delivery, as well as safer and more efficacious oral delivery of drugs and drug combinations. PMID:26181279

  20. Dendrimer-like hybrid particles with tunable hierarchical pores

    NASA Astrophysics Data System (ADS)

    Du, Xin; Li, Xiaoyu; Huang, Hongwei; He, Junhui; Zhang, Xueji

    2015-03-01

    Dendrimer-like silica particles with a center-radial dendritic framework and a synergistic hierarchical porosity have attracted much attention due to their unique open three-dimensional superstructures with high accessibility to the internal surface areas; however, the delicate regulation of the hierarchical porosity has been difficult to achieve up to now. Herein, a series of dendrimer-like amino-functionalized silica particles with tunable hierarchical pores (HPSNs-NH2) were successfully fabricated by carefully regulating and optimizing the various experimental parameters in the ethyl ether emulsion systems via a one-pot sol-gel reaction. Interestingly, the simple adjustment of the stirring rate or reaction temperature was found to be an easy and effective route to achieve the controllable regulation towards center-radial large pore sizes from ca. 37-267 (148 +/- 45) nm to ca. 8-119 (36 +/- 21) nm for HPSNs-NH2 with particle sizes of 300-700 nm and from ca. 9-157 (52 +/- 28) nm to ca. 8-105 (30 +/- 16) nm for HPSNs-NH2 with particle sizes of 100-320 nm. To the best of our knowledge, this is the first successful regulation towards center-radial large pore sizes in such large ranges. The formation of HPSNs-NH2 may be attributed to the complex cross-coupling of two processes: the dynamic diffusion of ethyl ether molecules and the self-assembly of partially hydrolyzed TEOS species and CTAB molecules at the dynamic ethyl ether-water interface of uniform small quasi-emulsion droplets. Thus, these results regarding the elaborate regulation of center-radial large pores and particle sizes not only help us better understand the complicated self-assembly at the dynamic oil-water interface, but also provide a unique and ideal platform as carriers or supports for adsorption, separation, catalysis, biomedicine, and sensor.Dendrimer-like silica particles with a center-radial dendritic framework and a synergistic hierarchical porosity have attracted much attention due to their

  1. Nano Ag-deposited BaTiO3 hybrid particles as fillers for polymeric dielectric composites: toward high dielectric constant and suppressed loss.

    PubMed

    Luo, Suibin; Yu, Shuhui; Sun, Rong; Wong, Ching-Ping

    2014-01-01

    Nano Ag-deposited BaTiO3 (BT-Ag) hybrid particles usable as fillers for flexible polymeric composites to obtain high dielectric constant, low conductivity, and low dielectric loss were developed. BT-Ag hybrid particles were synthesized via a seed-mediated growing process by a redox reaction between silver nitrate and ethylene glycol. Nano Ag particles with a size less than 20 nm were discretely grown on the surface of the 100 nm BaTiO3. The similar lattice spacing of the (1 1 1) planes of BT and Ag led to the hetero-epitaxial growth of Ag on the BT surface. The thickness of the coherent interface was about 3 nm. The adhesion of Ag to BT efficiently prevented the continuous contact between Ag particles in the polyvinylidene fluoride (PVDF) matrix and suppressed the formation of the conducting path in the composite. As a result, with a filler loading of 43.4 vol %, the composite exhibited a dielectric constant (Dk) value of 94.3 and dielectric loss (tan δ) of 0.06 at 1 kHz. An even higher Dk value of 160 at 1 kHz (16 times larger than that of PVDF) was obtained when the content of BT-Ag was further increased, with low conductivity (σ < 10(-5) S m(-1)) and low dielectric loss (tan δ = 0.11), demonstrating promising applications in the electronic devices. PMID:24320940

  2. Hybrid metal organic scintillator materials system and particle detector

    DOEpatents

    Bauer, Christina A.; Allendorf, Mark D.; Doty, F. Patrick; Simmons, Blake A.

    2011-07-26

    We describe the preparation and characterization of two zinc hybrid luminescent structures based on the flexible and emissive linker molecule, trans-(4-R,4'-R') stilbene, where R and R' are mono- or poly-coordinating groups, which retain their luminescence within these solid materials. For example, reaction of trans-4,4'-stilbenedicarboxylic acid and zinc nitrate in the solvent dimethylformamide (DMF) yielded a dense 2-D network featuring zinc in both octahedral and tetrahedral coordination environments connected by trans-stilbene links. Similar reaction in diethylformamide (DEF) at higher temperatures resulted in a porous, 3-D framework structure consisting of two interpenetrating cubic lattices, each featuring basic to zinc carboxylate vertices joined by trans-stilbene, analogous to the isoreticular MOF (IRMOF) series. We demonstrate that the optical properties of both embodiments correlate directly with the local ligand environments observed in the crystal structures. We further demonstrate that these materials produce high luminescent response to proton radiation and high radiation tolerance relative to prior scintillators. These features can be used to create sophisticated scintillating detection sensors.

  3. Hybrid molecular-continuum simulations using smoothed dissipative particle dynamics

    NASA Astrophysics Data System (ADS)

    Petsev, Nikolai D.; Leal, L. Gary; Shell, M. Scott

    2015-01-01

    We present a new multiscale simulation methodology for coupling a region with atomistic detail simulated via molecular dynamics (MD) to a numerical solution of the fluctuating Navier-Stokes equations obtained from smoothed dissipative particle dynamics (SDPD). In this approach, chemical potential gradients emerge due to differences in resolution within the total system and are reduced by introducing a pairwise thermodynamic force inside the buffer region between the two domains where particles change from MD to SDPD types. When combined with a multi-resolution SDPD approach, such as the one proposed by Kulkarni et al. [J. Chem. Phys. 138, 234105 (2013)], this method makes it possible to systematically couple atomistic models to arbitrarily coarse continuum domains modeled as SDPD fluids with varying resolution. We test this technique by showing that it correctly reproduces thermodynamic properties across the entire simulation domain for a simple Lennard-Jones fluid. Furthermore, we demonstrate that this approach is also suitable for non-equilibrium problems by applying it to simulations of the start up of shear flow. The robustness of the method is illustrated with two different flow scenarios in which shear forces act in directions parallel and perpendicular to the interface separating the continuum and atomistic domains. In both cases, we obtain the correct transient velocity profile. We also perform a triple-scale shear flow simulation where we include two SDPD regions with different resolutions in addition to a MD domain, illustrating the feasibility of a three-scale coupling.

  4. Hybrid molecular-continuum simulations using smoothed dissipative particle dynamics

    SciTech Connect

    Petsev, Nikolai D.; Leal, L. Gary; Shell, M. Scott

    2015-01-28

    We present a new multiscale simulation methodology for coupling a region with atomistic detail simulated via molecular dynamics (MD) to a numerical solution of the fluctuating Navier-Stokes equations obtained from smoothed dissipative particle dynamics (SDPD). In this approach, chemical potential gradients emerge due to differences in resolution within the total system and are reduced by introducing a pairwise thermodynamic force inside the buffer region between the two domains where particles change from MD to SDPD types. When combined with a multi-resolution SDPD approach, such as the one proposed by Kulkarni et al. [J. Chem. Phys. 138, 234105 (2013)], this method makes it possible to systematically couple atomistic models to arbitrarily coarse continuum domains modeled as SDPD fluids with varying resolution. We test this technique by showing that it correctly reproduces thermodynamic properties across the entire simulation domain for a simple Lennard-Jones fluid. Furthermore, we demonstrate that this approach is also suitable for non-equilibrium problems by applying it to simulations of the start up of shear flow. The robustness of the method is illustrated with two different flow scenarios in which shear forces act in directions parallel and perpendicular to the interface separating the continuum and atomistic domains. In both cases, we obtain the correct transient velocity profile. We also perform a triple-scale shear flow simulation where we include two SDPD regions with different resolutions in addition to a MD domain, illustrating the feasibility of a three-scale coupling.

  5. Nonlinear electromagnetic gyrokinetic particle simulations with the electron hybrid model

    NASA Astrophysics Data System (ADS)

    Nishimura, Y.; Lin, Z.; Chen, L.; Hahm, T.; Wang, W.; Lee, W.

    2006-10-01

    The electromagnetic model with fluid electrons is successfully implemented into the global gyrokinetic code GTC. In the ideal MHD limit, shear Alfven wave oscillation and continuum damping is demonstrated. Nonlinear electromagnetic simulation is further pursued in the presence of finite ηi. Turbulence transport in the AITG unstable β regime is studied. This work is supported by Department of Energy (DOE) Grant DE-FG02-03ER54724, Cooperative Agreement No. DE-FC02-04ER54796 (UCI), DOE Contract No. DE-AC02-76CH03073 (PPPL), and in part by SciDAC Center for Gyrokinetic Particle Simulation of Turbulent Transport in Burning Plasmas. Z. Lin, et al., Science 281, 1835 (1998). F. Zonca and L. Chen, Plasma Phys. Controlled Fusion 30, 2240 (1998); G. Zhao and L. Chen, Phys. Plasmas 9, 861 (2002).

  6. Synthesis and properties of hybrid hydroxyapatite-ferrite (Fe3O4) particles for hyperthermia applications

    NASA Astrophysics Data System (ADS)

    Tkachenko, M. V.; Kamzin, A. S.

    2016-04-01

    Hybrid ceramics consisting of hydroxyapatite Ca10(PO4)6(OH)2 and ferrite Fe3O4 were synthesized using a two-stage procedure. The first stage included the synthesis of Fe3O4 ferrite particles by co-precipitation and the synthesis of hydroxyapatite. In the second stage, the magnetic hybrid hydroxyapatite-ferrite bioceramics were synthesized by a thorough mixing of the obtained powders of carbonated hydroxyapatite and Fe3O4 ferrite taken in a certain proportion, pressing into tablets, and annealing in a carbon dioxide atmosphere for 30 min at a temperature of 1200°C. The properties of the components and hybrid particles were investigated using X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and Mössbauer spectroscopy. The saturation magnetization of the hybrid ceramic composite containing 20 wt % Fe3O4 was found to be 12 emu/g. The hybrid hydroxyapatite (Ca10(PO4)6(OH)2)-ferrite Fe3O4 ceramics, which are promising for the use in magnetotransport and hyperthermia treatment, were synthesized and investigated for the first time.

  7. Investigating ICRF Core Physics with a Hybrid Method using δf Particles

    NASA Astrophysics Data System (ADS)

    Austin, T. M.; Smithe, D. N.

    2011-12-01

    Particle-in-cell simulations of ICRF core physics yield a significant amount of noise that can overwhelm the low amplitude signals associated with ICRH. To overcome this noise, we employ a hybrid approach that uses a fluid model for electrons and the delta-f particle-in-cell (DFPIC) method for ions. Noise is reduced to a level well below the amplitude of the signal and time steps are permitted to go beyond the electron time scales. With this formulation we have explored minority heating scenarios in Alcator C-Mod and high harmonic heating scenarios in NSTX. We can also employ the fluid model for both electrons and ions to investigate cold plasma scenarios. Here we examine ion test particles with particular attention paid to particle paths near resonance layers. We present our technique for investigating full particle orbits from a single toroidal mode expansion.

  8. Exponential-characteristic spatial quadrature for discrete-ordinates neutral-particle transport in slab geometry. Master's thesis

    SciTech Connect

    Sjoden, G.E.

    1992-03-01

    A new discrete ordinates spatial quadrature scheme is presented for solving neutral particle transport problems. This new scheme, called the exponential characteristic method, is developed here in slab geometry with isotropic scattering. This method uses a characteristic integration of the Boltzmann transport equation with an exponential function as the assumed from of the source distribution, continuous across each spatial cell. The exponential source function is constructed to globally conserve zeroth and first spatial source moments and is non-negative. Characteristic integration ensures non-negative fluxes and flux moments. Numerical testing indicates that convergence of the exponential characteristic scheme is fourth order in the limit of vanishingly thin cells. Highly accurate solutions to optically thick problems can result using this scheme with very coarse meshes. Comparing accuracy and computational cost with existing spatial quadrature schemes (diamond difference, linear discontinuous, linear characteristic, linear adaptive, etc.), the exponential characteristic scheme typically performed best. This scheme is expected to be expandable to two dimensions in a straight forward manner. Due to the high accuracies achievable using coarse meshes, this scheme may allow researchers to obtain solutions to transport problems once thought too large or too difficult to be adequately solved conventional computer systems.

  9. Discrete-Element bonded-particle Sea Ice model DESIgn, version 1.3a - model description and implementation

    NASA Astrophysics Data System (ADS)

    Herman, Agnieszka

    2016-04-01

    This paper presents theoretical foundations, numerical implementation and examples of application of the two-dimensional Discrete-Element bonded-particle Sea Ice model - DESIgn. In the model, sea ice is represented as an assemblage of objects of two types: disk-shaped "grains" and semi-elastic bonds connecting them. Grains move on the sea surface under the influence of forces from the atmosphere and the ocean, as well as interactions with surrounding grains through direct contact (Hertzian contact mechanics) and/or through bonds. The model has an experimental option of taking into account quasi-three-dimensional effects related to the space- and time-varying curvature of the sea surface, thus enabling simulation of ice breaking due to stresses resulting from bending moments associated with surface waves. Examples of the model's application to simple sea ice deformation and breaking problems are presented, with an analysis of the influence of the basic model parameters ("microscopic" properties of grains and bonds) on the large-scale response of the modeled material. The model is written as a toolbox suitable for usage with the open-source numerical library LIGGGHTS. The code, together with full technical documentation and example input files, is freely available with this paper and on the Internet.

  10. Enhancement of the Wear Particle Monitoring Capability of Oil Debris Sensors Using a Maximal Overlap Discrete Wavelet Transform with Optimal Decomposition Depth

    PubMed Central

    Li, Chuan; Peng, Juan; Liang, Ming

    2014-01-01

    Oil debris sensors are effective tools to monitor wear particles in lubricants. For in situ applications, surrounding noise and vibration interferences often distort the oil debris signature of the sensor. Hence extracting oil debris signatures from sensor signals is a challenging task for wear particle monitoring. In this paper we employ the maximal overlap discrete wavelet transform (MODWT) with optimal decomposition depth to enhance the wear particle monitoring capability. The sensor signal is decomposed by the MODWT into different depths for detecting the wear particle existence. To extract the authentic particle signature with minimal distortion, the root mean square deviation of kurtosis value of the segmented signal residue is adopted as a criterion to obtain the optimal decomposition depth for the MODWT. The proposed approach is evaluated using both simulated and experimental wear particles. The results show that the present method can improve the oil debris monitoring capability without structural upgrade requirements. PMID:24686730

  11. (Bio)hybrid materials based on optically active particles

    NASA Astrophysics Data System (ADS)

    Reitzig, Manuela; Härtling, Thomas; Opitz, Jörg

    2014-03-01

    In this contribution we provide an overview of current investigations on optically active particles (nanodiamonds, upconversion phospors) for biohybrid and sensing applications. Due to their outstanding properties nanodiamonds gain attention in various application elds such as microelectronics, optical monitoring, medicine, and biotechnology. Beyond the typical diamond properties such as high thermal conductivity and extreme hardness, the carbon surface and its various functional groups enable diverse chemical and biological surface functionalization. At Fraunhofer IKTS-MD we develop a customization of material surfaces via integration of chemically modi ed nanodiamonds at variable surfaces, e.g bone implants and pipelines. For the rst purpose, nanodiamonds are covalently modi ed at their surface with amino or phosphate functionalities that are known to increase adhesion to bone or titanium alloys. The second type of surface is approached via mechanical implementation into coatings. Besides nanodiamonds, we also investigate the properties of upconversion phosphors. In our contribution we show how upconversion phosphors are used to verify sterilization processes via a change of optical properties due to sterilizing electron beam exposure.

  12. Optimal Control for a Parallel Hybrid Hydraulic Excavator Using Particle Swarm Optimization

    PubMed Central

    Wang, Dong-yun; Guan, Chen

    2013-01-01

    Optimal control using particle swarm optimization (PSO) is put forward in a parallel hybrid hydraulic excavator (PHHE). A power-train mathematical model of PHHE is illustrated along with the analysis of components' parameters. Then, the optimal control problem is addressed, and PSO algorithm is introduced to deal with this nonlinear optimal problem which contains lots of inequality/equality constraints. Then, the comparisons between the optimal control and rule-based one are made, and the results show that hybrids with the optimal control would increase fuel economy. Although PSO algorithm is off-line optimization, still it would bring performance benchmark for PHHE and also help have a deep insight into hybrid excavators. PMID:23818832

  13. A Fast Induction Motor Speed Estimation based on Hybrid Particle Swarm Optimization (HPSO)

    NASA Astrophysics Data System (ADS)

    Aryza, Solly; Abdallah, Ahmed N.; Khalidin, Zulkeflee bin; Lubis, Zulkarnain; Jie, Ma

    Intelligent control and estimation of power electronic systems by fuzzy logic and neural network techniques with fast torque and flux show tremendous promise in future. This paper proposed the application of Hybrid Particle Swarm Optimization (HPSO) for losses and operating cost minimization control in the induction motor drives. The main advantages of the proposed technique are; its simple structure and its straightforward maximization of induction motor efficiency and its operating cost for a given load torque. As will be demonstrated, Hybrid Particle Swarm Optimization (HPSO) is so efficient in finding the optimum operating machine's flux level. The results demonstrate the good quality and robustness in the system dynamic response and reduction in the steady-state and transient motor ripple torque.

  14. Well-defined plate and hollow disk shaped particles of silica-dialkyldimethylammonium hybrids.

    PubMed

    Machida, Shingo; Yoshida, Takaaki; Hashimoto, Ryouya; Ogawa, Makoto

    2014-04-15

    Well-defined plate and hollow disk of silica-dioctadecyldimethylammonium hybrid particles were obtained by the sol-gel reaction of tetraethoxysilane in the presence of dioctadecyldimethylammonium chloride, where synthetic condition was determined based on the Stöber synthesis for micron size silica sphere. The particle size was several hundreds of nm in the radius and several tens of nm in the thickness. X-ray powder diffraction patterns indicated that the products possess layered mesostructures, which were thought to be directed by the lamellar aggregates of dioctadecyldimethylammonium.

  15. Verification of electromagnetic fluid-kinetic hybrid electron model in global gyrokinetic particle simulation

    NASA Astrophysics Data System (ADS)

    Holod, I.; Lin, Z.

    2013-03-01

    The fluid-kinetic hybrid electron model is verified in global gyrokinetic particle simulation of linear electromagnetic drift-Alfvénic instabilities in tokamak. In particular, we have recovered the β-stabilization of the ion temperature gradient mode, transition to collisionless trapped electron mode, and the onset of kinetic ballooning mode as βe (ratio of electron kinetic pressure to magnetic pressure) increases.

  16. A frozen matrix hybrid optical nonlinear system enhanced by a particle lens

    NASA Astrophysics Data System (ADS)

    Chen, Lianwei; Zheng, Xiaorui; Du, Zheren; Jia, Baohua; Gu, Min; Hong, Minghui

    2015-09-01

    In this work, a Graphene Oxide (GO) nano-sheet and SiO2 micro-bead hybrid system based on a frozen matrix was investigated for its enhanced optical nonlinear performance. A frozen matrix is a novel approach that hosts the optical nonlinear nano-particles, which combines the strengths from both liquid and solid phase systems for high performance photonic applications. SiO2 micro-beads were used to induce a local field enhancement effect that improved the optical nonlinearity of GO nano-sheets. The nonlinear performance of the hybrid system is several orders higher than the existing GO nano-sheet liquid dispersion. In addition, this frozen matrix and the local field enhancement effect are two facile and versatile methods that can be applied to many types of nano-particle dispersions.In this work, a Graphene Oxide (GO) nano-sheet and SiO2 micro-bead hybrid system based on a frozen matrix was investigated for its enhanced optical nonlinear performance. A frozen matrix is a novel approach that hosts the optical nonlinear nano-particles, which combines the strengths from both liquid and solid phase systems for high performance photonic applications. SiO2 micro-beads were used to induce a local field enhancement effect that improved the optical nonlinearity of GO nano-sheets. The nonlinear performance of the hybrid system is several orders higher than the existing GO nano-sheet liquid dispersion. In addition, this frozen matrix and the local field enhancement effect are two facile and versatile methods that can be applied to many types of nano-particle dispersions. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr03304g

  17. Ultrasensitive Cracking-Assisted Strain Sensors Based on Silver Nanowires/Graphene Hybrid Particles.

    PubMed

    Chen, Song; Wei, Yong; Wei, Siman; Lin, Yong; Liu, Lan

    2016-09-28

    Strain sensors with ultrahigh sensitivity under microstrain have numerous potential applications in heartbeat monitoring, pulsebeat detection, sound signal acquisition, and recognition. In this work, a two-part strain sensor (i.e., polyurethane part and brittle conductive hybrid particles layer on top) based on silver nanowires/graphene hybrid particles is developed via a simple coprecipitation, reduction, vacuum filtration, and casting process. Because of the nonuniform interface, weak interfacial bonding, and the hybrid particles' point-to-point conductive networks, the crack and overlap morphologies are successfully formed on the strain sensor after a prestretching; the crack-based stain sensor exhibits gauge factors as high as 20 (Δε < 0.3%), 1000 (0.3% < Δε < 0.5%), and 4000 (0.8% < Δε < 1%). In addition, we demonstrate the sensing mechanism under strain results in the high gauge factor of the strain sensor. Combined with its good response to bending, high strain resolution, and high working stability, the developed strain sensor is promising in the applications of electronic skins, motion sensors, and health monitoring sensors.

  18. Ultrasensitive Cracking-Assisted Strain Sensors Based on Silver Nanowires/Graphene Hybrid Particles.

    PubMed

    Chen, Song; Wei, Yong; Wei, Siman; Lin, Yong; Liu, Lan

    2016-09-28

    Strain sensors with ultrahigh sensitivity under microstrain have numerous potential applications in heartbeat monitoring, pulsebeat detection, sound signal acquisition, and recognition. In this work, a two-part strain sensor (i.e., polyurethane part and brittle conductive hybrid particles layer on top) based on silver nanowires/graphene hybrid particles is developed via a simple coprecipitation, reduction, vacuum filtration, and casting process. Because of the nonuniform interface, weak interfacial bonding, and the hybrid particles' point-to-point conductive networks, the crack and overlap morphologies are successfully formed on the strain sensor after a prestretching; the crack-based stain sensor exhibits gauge factors as high as 20 (Δε < 0.3%), 1000 (0.3% < Δε < 0.5%), and 4000 (0.8% < Δε < 1%). In addition, we demonstrate the sensing mechanism under strain results in the high gauge factor of the strain sensor. Combined with its good response to bending, high strain resolution, and high working stability, the developed strain sensor is promising in the applications of electronic skins, motion sensors, and health monitoring sensors. PMID:27599264

  19. Effect of Thermally Softened Bronze Matrix on the Fracturing Behavior of Diamond Particles in Hybrid Sprayed Bronze/Diamond Composite

    NASA Astrophysics Data System (ADS)

    Na, Hyuntaek; Bae, Gyuyeol; Kang, Kicheol; Kim, Hyungjun; Kim, Jay-Jung; Lee, Changhee

    2010-09-01

    In our previous study (Na et al., Compos Sci Technol 69:463-468, 2009), optimized thickness of protective nickel film was proposed for smaller diamond feedstock to obtain reduced impact stress and uniform flight behavior of particles during kinetic (or cold) spraying. However, in this study, nickel-coated diamond particles were severely fractured with increasing particle size due to high kinetic energy. Hence, an innovative hybrid spraying technique (a combination of kinetic and thermal spraying) was introduced to embed relatively large diamond particles into the bronze matrix. Size distributions of the diamond particles in the composite coatings were analyzed by scanning electron microscopy, an electron probe micro analyzer, and image analysis methods. In addition, impact behaviors of diamond particles in kinetic and hybrid gas flows were simulated through finite element analysis (ABAQUS/Explicit 6.7-2). Diamond fracturing was significantly minimized by the reduced impact energy afforded by the thermally softened bronze matrix through hybrid spraying.

  20. Silica hybrid particles with nanometre polymer shells and their influence on the toughening of polypropylene.

    PubMed

    Zheng, Jing-Zhi; Zhou, Xing-Ping; Xie, Xiao-Lin; Mai, Yiu-Wing

    2010-10-01

    Colloidal silica particles were synthesized by the sol-gel process and then modified with 3-methacryloxypropyltrimethoxysilane (γ-MPS) to induce vinyl groups on the surface of the silica particles. By means of in situ emulsion copolymerization of methyl methacrylate (MMA) and butyl acrylate (BA), a series of core-shell silica hybrid particles with nanometre poly(MMA-co-BA) shells were fabricated, which were subsequently compounded with isotactic polypropylene (PP) in the molten state. Upon increasing the feed silica : monomer ratio from 1 : 1 to 4 : 1, the poly(MMA-co-BA) shell thickness on the silica core decreased from 50 nm to 10 nm. Owing to the existence of the nanometre poly(MMA-co-BA) shells, the silica hybrid particles were monodispersed in the PP matrix, causing homogeneous debonding at the PP/silica interface, followed by plastic void expansion and matrix shear yielding during impact fracture. These deformation mechanisms greatly toughened the PP-silica composites. A critical shell thickness of poly(MMA-co-BA) was needed to achieve optimal mechanical properties. That is, when the polymer shell thickness was 15 nm, compared to pure PP, the impact toughness of the PP-silica composite was more than doubled with little degradation of tensile strength. PMID:20730152

  1. Immunity to malaria elicited by hybrid hepatitis B virus core particles carrying circumsporozoite protein epitopes

    PubMed Central

    1994-01-01

    The hepatitis B virus (HBV) nucleocapsid antigen (HBcAg) was investigated as a carrier moiety for the immunodominant circumsporozoite (CS) protein repeat epitopes of Plasmodium falciparum and the rodent malaria agent P. berghei. For this purpose hybrid genes coding for [NANP]4 (C75CS2) or [DP4NPN]2 (C75CS1) as internal inserts in HBcAg (between amino acids 75 and 81) were constructed and expressed in recombinant Salmonella typhimurium. The resulting hybrid HBcAg-CS polypeptides purified from S. typhimurium were particulate and displayed CS and HBc antigenicity, however, the HBc antigenicity was reduced compared to native recombinant HBcAg. Immunization of several mouse strains with HBcAg-CS1 and HBcAg-CS2 particles resulted in high titer, P.berghei- or P.falciparum-specific anti-CS antibodies representing all murine immunoglobulin G isotypes. The possible influence of carrier-specific immunosuppression was examined, and preexisting immunity to HBcAg did not significantly affect the immunogenicity of the CS epitopes within HBcAg-CS1 particles. Similarly, the choice of adjuvant did not significantly alter the immunogenicity of HBcAg-CS hybrid particles. Immunization in complete or incomplete Freund's adjuvant or alum resulted in equivalent anti-HBc and anti-CS humoral responses. Examination of T cell recognition of HBcAg-CS particles revealed that HBcAg-specific T cells were universally primed and CS-specific T cells were primed if the insert contained a CS-specific T cell recognition site. This indicates that the internal site in HBcAg is permissive for the inclusion of heterologous pathogen-specific T as well as B cell epitopes. Most importantly, 90 and 100% of BALB/c mice immunized with HBcAg-CS1 particles were protected against a P. berghei challenge infection in two independent experiments. Therefore, hybrid HBcAg-CS particles may represent a useful approach for future malaria vaccine development. PMID:7520465

  2. 3D hybrid simulations with gyrokinetic particle ions and fluid electrons

    SciTech Connect

    Belova, E.V.; Park, W.; Fu, G.Y.; Strauss, H.R.; Sugiyama, L.E.

    1998-12-31

    The previous hybrid MHD/particle model (MH3D-K code) represented energetic ions as gyrokinetic (or drift-kinetic) particles coupled to MHD equations using the pressure or current coupling scheme. A small energetic to bulk ion density ratio was assumed, n{sub h}/n{sub b} {much_lt} 1, allowing the neglect of the energetic ion perpendicular inertia in the momentum equation and the use of MHD Ohm`s law E = {minus}v{sub b} {times} B. A generalization of this model in which all ions are treated as gyrokinetic/drift-kinetic particles and fluid description is used for the electron dynamics is considered in this paper.

  3. Particle deposition in a full scale hybrid electrostatic-filtration collector

    NASA Astrophysics Data System (ADS)

    Long, Zhengwei; Yao, Qiang

    2013-03-01

    This paper presents a numerical model for a full scale hybrid particulate collector (HPC), which combines the ESP technology and the filtration technology together. The corona discharge is solved by using a finite volume method. The turbulent flow equations are solved by using the Fluent package. The effect of the electric field on the fluid field named electro-hydrodynamic is considered. The particle motion is calculated by using the Lagrangian method. The particle charging rate is calculated by using a filed-diffusing combined model. The bag is modelled as a porous media but the pressure drop across the particle cake is neglected. Eight particle sizes are considered: 0.01, 0.1, 0.3, 0.5, 1, 2, 5 and 10 μm. The applied voltage is fixed at 60 kV. The results show that the collection efficiency of the electrostatic zone changes a little when the particle size is below 0.3 μm but increases clearly when the particle size exceeds 0.3 μm. Totally, the bag collection efficiency decreases from the first one to the last one in the same row.

  4. Correlation of Particle Traversals with Clonogenic Survival Using Cell-Fluorescent Ion Track Hybrid Detector.

    PubMed

    Dokic, Ivana; Niklas, Martin; Zimmermann, Ferdinand; Mairani, Andrea; Seidel, Philipp; Krunic, Damir; Jäkel, Oliver; Debus, Jürgen; Greilich, Steffen; Abdollahi, Amir

    2015-01-01

    Development of novel approaches linking the physical characteristics of particles with biological responses are of high relevance for the field of particle therapy. In radiobiology, the clonogenic survival of cells is considered the gold standard assay for the assessment of cellular sensitivity to ionizing radiation. Toward further development of next generation biodosimeters in particle therapy, cell-fluorescent ion track hybrid detector (Cell-FIT-HD) was recently engineered by our group and successfully employed to study physical particle track information in correlation with irradiation-induced DNA damage in cell nuclei. In this work, we investigated the feasibility of Cell-FIT-HD as a tool to study the effects of clinical beams on cellular clonogenic survival. Tumor cells were grown on the fluorescent nuclear track detector as cell culture, mimicking the standard procedures for clonogenic assay. Cell-FIT-HD was used to detect the spatial distribution of particle tracks within colony-initiating cells. The physical data were associated with radiation-induced foci as surrogates for DNA double-strand breaks, the hallmark of radiation-induced cell lethality. Long-term cell fate was monitored to determine the ability of cells to form colonies. We report the first successful detection of particle traversal within colony-initiating cells at subcellular resolution using Cell-FIT-HD.

  5. Development of flash nanoprecipitation as a scalable platform for production of hybrid polymer-inorganic Janus particles

    NASA Astrophysics Data System (ADS)

    Lee, Victoria E.; Prud'Homme, Robert K.; Priestley, Rodney D.

    Polymer Janus particles, containing two or more distinct domains, can act as supports for inorganic nanoparticles, stabilizing them against aggregation and templating anisotropic functionalization of the microparticles. This anisotropy can be advantageous for applications such as biofuel upgrading, bionanosensors, and responsive materials. Here, we introduce flash nanoprecipitation (FNP) as a scalable, fast process to create hybrid polymer-inorganic Janus particles with control of particle size and anisotropy. During FNP, polymer Janus particles form by rapid intermixing of a polymer solution with a poor solvent, inducing polymer precipitation and phase separation. Inorganic nanoparticles are then adsorbed selectively onto one domain of the polymer support by exploiting electrostatic interactions between the charged particles. By tuning polymer concentration and ratio in the feed stream, the particle size and anisotropy can be controlled. We further demonstrate that these hybrid particles can simultaneously stabilize emulsions and selectively catalyze the degradation of dye in one phase. With support from the Princeton Imaging Analysis Center.

  6. Modeling of MeV alpha particle energy transfer to lower hybrid waves

    SciTech Connect

    Schivell, J.; Monticello, D.A.; Fisch, N.; Rax, J.M.

    1993-10-01

    The interaction between a lower hybrid wave and a fusion alpha particle displaces the alpha particle simultaneously in space and energy. This results in coupled diffusion. Diffusion of alphas down the density gradient could lead to their transferring energy to the wave. This could, in turn, put energy into current drive. An initial analytic study was done by Fisch and Rax. Here the authors calculate numerical solutions for the alpha energy transfer and study a range of conditions that are favorable for wave amplification from alpha energy. They find that it is possible for fusion alpha particles to transfer a large fraction of their energy to the lower hybrid wave. The numerical calculation shows that the net energy transfer is not sensitive to the value of the diffusion coefficient over a wide range of practical values. An extension of this idea, the use of a lossy boundary to enhance the energy transfer, is investigated. This technique is shown to offer a large potential benefit.

  7. Hierarchical Self-Assembly of Polyoxometalate-Based Hybrids Driven by Metal Coordination and Electrostatic Interactions: From Discrete Supramolecular Species to Dense Monodisperse Nanoparticles.

    PubMed

    Izzet, Guillaume; Abécassis, Benjamin; Brouri, Dalil; Piot, Madeleine; Matt, Benjamin; Serapian, Stefano Artin; Bo, Carles; Proust, Anna

    2016-04-20

    The metal-driven self-assembly processes of a covalent polyoxometalate (POM)-based hybrid bearing remote terpyridine binding sites have been investigated. In a strongly dissociating solvent, a discrete metallomacrocycle, described as a molecular triangle, is formed and characterized by 2D diffusion NMR spectroscopy (DOSY), small-angle X-ray scattering (SAXS), and molecular modeling. In a less dissociating solvent, the primary supramolecular structure, combining negatively charged POMs and cationic metal linkers, further self-assemble through intermolecular electrostatic interactions in a reversible process. The resulting hierarchical assemblies are dense monodisperse nanoparticles composed of ca. 50 POMs that were characterized by SAXS and transmission electron microscopy (TEM). This multiscale organized system directed by metal coordination and electrostatic interactions constitutes a promising step for the future design of POM self-assemblies with controllable structure-directing factors. PMID:27019075

  8. Exact hybrid particle/population simulation of rule-based models of biochemical systems.

    PubMed

    Hogg, Justin S; Harris, Leonard A; Stover, Lori J; Nair, Niketh S; Faeder, James R

    2014-04-01

    Detailed modeling and simulation of biochemical systems is complicated by the problem of combinatorial complexity, an explosion in the number of species and reactions due to myriad protein-protein interactions and post-translational modifications. Rule-based modeling overcomes this problem by representing molecules as structured objects and encoding their interactions as pattern-based rules. This greatly simplifies the process of model specification, avoiding the tedious and error prone task of manually enumerating all species and reactions that can potentially exist in a system. From a simulation perspective, rule-based models can be expanded algorithmically into fully-enumerated reaction networks and simulated using a variety of network-based simulation methods, such as ordinary differential equations or Gillespie's algorithm, provided that the network is not exceedingly large. Alternatively, rule-based models can be simulated directly using particle-based kinetic Monte Carlo methods. This "network-free" approach produces exact stochastic trajectories with a computational cost that is independent of network size. However, memory and run time costs increase with the number of particles, limiting the size of system that can be feasibly simulated. Here, we present a hybrid particle/population simulation method that combines the best attributes of both the network-based and network-free approaches. The method takes as input a rule-based model and a user-specified subset of species to treat as population variables rather than as particles. The model is then transformed by a process of "partial network expansion" into a dynamically equivalent form that can be simulated using a population-adapted network-free simulator. The transformation method has been implemented within the open-source rule-based modeling platform BioNetGen, and resulting hybrid models can be simulated using the particle-based simulator NFsim. Performance tests show that significant memory savings

  9. Investigation of Micro- and Nanosized Particle Erosion in a 90° Pipe Bend Using a Two-Phase Discrete Phase Model

    PubMed Central

    Safaei, M. R.; Mahian, O.; Garoosi, F.; Hooman, K.; Karimipour, A.; Kazi, S. N.; Gharehkhani, S.

    2014-01-01

    This paper addresses erosion prediction in 3-D, 90° elbow for two-phase (solid and liquid) turbulent flow with low volume fraction of copper. For a range of particle sizes from 10 nm to 100 microns and particle volume fractions from 0.00 to 0.04, the simulations were performed for the velocity range of 5–20 m/s. The 3-D governing differential equations were discretized using finite volume method. The influences of size and concentration of micro- and nanoparticles, shear forces, and turbulence on erosion behavior of fluid flow were studied. The model predictions are compared with the earlier studies and a good agreement is found. The results indicate that the erosion rate is directly dependent on particles' size and volume fraction as well as flow velocity. It has been observed that the maximum pressure has direct relationship with the particle volume fraction and velocity but has a reverse relationship with the particle diameter. It also has been noted that there is a threshold velocity as well as a threshold particle size, beyond which significant erosion effects kick in. The average friction factor is independent of the particle size and volume fraction at a given fluid velocity but increases with the increase of inlet velocities. PMID:25379542

  10. Investigation of micro- and nanosized particle erosion in a 90° pipe bend using a two-phase discrete phase model.

    PubMed

    Safaei, M R; Mahian, O; Garoosi, F; Hooman, K; Karimipour, A; Kazi, S N; Gharehkhani, S

    2014-01-01

    This paper addresses erosion prediction in 3-D, 90° elbow for two-phase (solid and liquid) turbulent flow with low volume fraction of copper. For a range of particle sizes from 10 nm to 100 microns and particle volume fractions from 0.00 to 0.04, the simulations were performed for the velocity range of 5-20 m/s. The 3-D governing differential equations were discretized using finite volume method. The influences of size and concentration of micro- and nanoparticles, shear forces, and turbulence on erosion behavior of fluid flow were studied. The model predictions are compared with the earlier studies and a good agreement is found. The results indicate that the erosion rate is directly dependent on particles' size and volume fraction as well as flow velocity. It has been observed that the maximum pressure has direct relationship with the particle volume fraction and velocity but has a reverse relationship with the particle diameter. It also has been noted that there is a threshold velocity as well as a threshold particle size, beyond which significant erosion effects kick in. The average friction factor is independent of the particle size and volume fraction at a given fluid velocity but increases with the increase of inlet velocities.

  11. Delta-doped hybrid advanced detector for low energy particle detection

    NASA Technical Reports Server (NTRS)

    Cunningham, Thomas J. (Inventor); Fossum, Eric R. (Inventor); Nikzad, Shouleh (Inventor); Pain, Bedabrata (Inventor); Soli, George A. (Inventor)

    2000-01-01

    A delta-doped hybrid advanced detector (HAD) is provided which combines at least four types of technologies to create a detector for energetic particles ranging in energy from hundreds of electron volts (eV) to beyond several million eV. The detector is sensitive to photons from visible light to X-rays. The detector is highly energy-sensitive from approximately 10 keV down to hundreds of eV. The detector operates with milliwatt power dissipation, and allows non-sequential readout of the array, enabling various advanced readout schemes.

  12. Delta-doped hybrid advanced detector for low energy particle detection

    NASA Technical Reports Server (NTRS)

    Cunningham, Thomas J. (Inventor); Fossum, Eric R. (Inventor); Nikzad, Shouleh (Inventor); Pain, Bedabrata (Inventor); Soli, George A. (Inventor)

    2002-01-01

    A delta-doped hybrid advanced detector (HAD) is provided which combines at least four types of technologies to create a detector for energetic particles ranging in energy from hundreds of electron volts (eV) to beyond several million eV. The detector is sensitive to photons from visible light to X-rays. The detector is highly energy-sensitive from approximately 10 keV down to hundreds of eV. The detector operates with milliwatt power dissipation, and allows non-sequential readout of the array, enabling various advanced readout schemes.

  13. Enhancement of hybrid rocket combustion performance using nano-sized energetic particles

    NASA Astrophysics Data System (ADS)

    Risha, Grant Alexander

    Until now, the regression rate of classical hybrid rocket engines have typically been an order of magnitude lower than solid propellant motors; thus, hybrids require a relatively large fuel surface area for a given thrust level. In addition to low linear regression rates, relatively low combustion efficiency (87 to 92%), low mass burning rates, varying oxidizer-to-fuel ratio during operation, and lack of scaling laws have been reported. These disadvantages can be ameliorated by introducing nano-sized energetic powder additives into the solid fuel. The addition of nano-sized energetic particles into the solid fuel enhances performance as measured by parameters such as: density specific impulse, mass and linear burning rates, and thrust. Thermophysical properties of the solid fuel such as density, heat of combustion, thermal diffusivity, and thermal conductivity are also enhanced. The types of nano-sized energetic particles used in this study include aluminum, boron, boron carbide, and some Viton-A coated particles. Since the combustion process of solid fuels in a hybrid rocket engine is governed by the mass flux of the oxidizer entering the combustion chamber, the rate-limiting process is the mixing and reacting of the pyrolysis products of the fuel grain with the incoming oxidizer. The overall goal of this research was to determine the relative propulsive and combustion behavior for a family of newly-developed HTPB-based solid-fuel formulations containing various nano-sized energetic particles. Seventeen formulations contained 13% additive by weight, one formulation (SF4) contained 6.5% additive by weight, and one formulation (SF19) contained 5.65% boron by weight. The two hybrid rocket engines which were used in this investigation were the Long Grain Center-Perforated (LGCP) rocket engine and the X-Ray Transparent Casing (XTC) rocket engine. The smaller scale LGCP rocket engine was used to evaluate all of the formulations because conducting experiments using the

  14. Adaptive hybrid likelihood model for visual tracking based on Gaussian particle filter

    NASA Astrophysics Data System (ADS)

    Wang, Yong; Tan, Yihua; Tian, Jinwen

    2010-07-01

    We present a new scheme based on multiple-cue integration for visual tracking within a Gaussian particle filter framework. The proposed method integrates the color, shape, and texture cues of an object to construct a hybrid likelihood model. During the measurement step, the likelihood model can be switched adaptively according to environmental changes, which improves the object representation to deal with the complex disturbances, such as appearance changes, partial occlusions, and significant clutter. Moreover, the confidence weights of the cues are adjusted online through the estimation using a particle filter, which ensures the tracking accuracy and reliability. Experiments are conducted on several real video sequences, and the results demonstrate that the proposed method can effectively track objects in complex scenarios. Compared with previous similar approaches through some quantitative and qualitative evaluations, the proposed method performs better in terms of tracking robustness and precision.

  15. Further validation of the hybrid particle-mesh method for vortex shedding flow simulations

    NASA Astrophysics Data System (ADS)

    Lee, Seung-Jae; Lee, Jun-Hyeok; Suh, Jung-Chun

    2015-11-01

    This is the continuation of a numerical study on vortex shedding from a blunt trailing-edge of a hydrofoil. In our previous work (Lee et al., 2015), numerical schemes for efficient computations were successfully implemented; i.e. multiple domains, the approximation of domain boundary conditions using cubic spline functions, and particle-based domain decomposition for better load balancing. In this study, numerical results through a hybrid particle-mesh method which adopts the Vortex-In-Cell (VIC) method and the Brinkman penalization model are further rigorously validated through comparison to experimental data at the Reynolds number of 2 × 106. The effects of changes in numerical parameters are also explored herein. We find that the present numerical method enables us to reasonably simulate vortex shedding phenomenon, as well as turbulent wakes of a hydrofoil.

  16. A hybrid particle-mesh method for incompressible active polar viscous gels

    NASA Astrophysics Data System (ADS)

    Ramaswamy, Rajesh; Bourantas, George; Jülicher, Frank; Sbalzarini, Ivo F.

    2015-06-01

    We present a hybrid particle-mesh method for numerically solving the hydrodynamic equations of incompressible active polar viscous gels. These equations model the dynamics of polar active agents, embedded in a viscous medium, in which stresses are induced through constant consumption of energy. The numerical method is based on Lagrangian particles and staggered Cartesian finite-difference meshes. We show that the method is second-order and first-order accurate with respect to grid and time-step sizes, respectively. Using the present method, we simulate the hydrodynamics in rectangular geometries, of a passive liquid crystal, of an active polar film and of active gels with topological defects in polarization. We show the emergence of spontaneous flow due to Fréedericksz transition, and transformation in the nature of topological defects by tuning the activity of the system.

  17. Cross-protection conferred by filovirus virus-like particles containing trimeric hybrid glycoprotein.

    PubMed

    Martins, Karen; Carra, John H; Cooper, Christopher L; Kwilas, Steven A; Robinson, Camenzind G; Shurtleff, Amy C; Schokman, Rowena D; Kuehl, Kathleen A; Wells, Jay B; Steffens, Jesse T; van Tongeren, Sean A; Hooper, Jay W; Bavari, Sina

    2015-02-01

    Filoviruses are causative agents of hemorrhagic fever, and to date no effective vaccine or therapeutic has been approved to combat infection. Filovirus glycoprotein (GP) is the critical immunogenic component of filovirus vaccines, eliciting high levels of antibody after successful vaccination. Previous work has shown that protection against both Ebola virus (EBOV) and Marburg virus (MARV) can be achieved by vaccinating with a mixture of virus-like particles (VLPs) expressing either EBOV GP or MARV GP. In this study, the potential for eliciting effective immune responses against EBOV, Sudan virus, and MARV with a single GP construct was tested. Trimeric hybrid GPs were produced that expressed the sequence of Marburg GP2 in conjunction with a hybrid GP1 composed EBOV and Sudan virus GP sequences. VLPs expressing these constructs, along with EBOV VP40, provided comparable protection against MARV challenge, resulting in 75 or 100% protection. Protection from EBOV challenge differed depending upon the hybrid used, however, with one conferring 75% protection and one conferring no protection. By comparing the overall antibody titers and the neutralizing antibody titers specific for each virus, it is shown that higher antibody responses were elicited by the C terminal region of GP1 than by the N terminal region, and this correlated with protection. These data collectively suggest that GP2 and the C terminal region of GP1 are highly immunogenic, and they advance progress toward the development of a pan-filovirus vaccine.

  18. Preparation and characterization of TiO 2-cationic hybrid nanoparticles as electrophoretic particles

    NASA Astrophysics Data System (ADS)

    Li, Jingjing; Deng, Liandong; Xing, Jinfeng; Dong, Anjie; Li, Xianggao

    2012-01-01

    The hybrid nanoparticles (TiO2-HNPs) with TiO2 nanoparticles as core and with poly(N,N-dimethylaminoethyl methacrylate-co-methyl methacrylate) by using triallylamine as cross-linking agent as shell were firstly prepared via atom transfer radical polymerization (ATRP) in methanol. Then the hybrid nanoparticles with positive charge were produced by the quaternization with methyl iodide as quaternization reagent so as to endow them with greater electrophoretic mobility. The cationic hybrid nanoparticles (TiO2-CHNPs) were studied by means of transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier-transform infrared (FTIR) spectroscopy and dynamic light scattering (DLS) measurements. The results indicate that the cationic polymer is successfully grafted on the surface of the TiO2 nanoparticles. The particle size of TiO2-CHNPs is about 150 nm and the polydispersity index (PDI) is 0.307. The zeta potential, the contrast ratio of white state to dark state and response time of TiO2-CHNPs are +16.8 mV, 30 and 3 s, respectively, which show the potential application prospect in the development of electrophoretic ink.

  19. Confocal Raman Microscopy of Hybrid-Supported Phospholipid Bilayers within Individual C18-Functionalized Chromatographic Particles.

    PubMed

    Kitt, Jay P; Harris, Joel M

    2016-09-01

    Measuring lipid-membrane partitioning of small molecules is critical to predicting bioavailability and investigating molecule-membrane interactions. A stable model membrane for such studies has been developed through assembly of a phospholipid monolayer on n-alkane-modified surfaces. These hybrid bilayers have recently been generated within n-alkyl-chain (C18)-modified porous silica and used in chromatographic retention studies of small molecules. Despite their successful application, determining the structure of hybrid bilayers within chromatographic silica is challenging because they reside at buried interfaces within the porous structure. In this work, we employ confocal Raman microscopy to investigate the formation and temperature-dependent structure of hybrid-phospholipid bilayers in C18-modified, porous-silica chromatographic particles. Porous silica provides sufficient surface area within a confocal probe volume centered in an individual particle to readily measure, with Raman microscopy, the formation of an ordered hybrid bilayer of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) with the surface C18 chains. The DMPC surface density was quantified from the relative Raman scattering intensities of C18 and phospholipid acyl chains and found to be ∼40% of a DMPC vesicle membrane. By monitoring Raman spectra acquired versus temperature, the bilayer main phase transition was observed to be broadened and shifted to higher temperature compared to a DMPC vesicle, in agreement with differential scanning calorimetry (DSC) results. Raman scattering of deuterated phospholipid was resolved from protonated C18 chain scattering, showing that the lipid acyl and C18 chains melt simultaneously in a single phase transition. The surface density of lipid in the hybrid bilayer, the ordering of both C18 and lipid acyl chains upon bilayer formation, and decoupling of C18 methylene C-H vibrations by deuterated lipid acyl chains all suggest an interdigitated acyl chain

  20. Confocal Raman Microscopy of Hybrid-Supported Phospholipid Bilayers within Individual C18-Functionalized Chromatographic Particles.

    PubMed

    Kitt, Jay P; Harris, Joel M

    2016-09-01

    Measuring lipid-membrane partitioning of small molecules is critical to predicting bioavailability and investigating molecule-membrane interactions. A stable model membrane for such studies has been developed through assembly of a phospholipid monolayer on n-alkane-modified surfaces. These hybrid bilayers have recently been generated within n-alkyl-chain (C18)-modified porous silica and used in chromatographic retention studies of small molecules. Despite their successful application, determining the structure of hybrid bilayers within chromatographic silica is challenging because they reside at buried interfaces within the porous structure. In this work, we employ confocal Raman microscopy to investigate the formation and temperature-dependent structure of hybrid-phospholipid bilayers in C18-modified, porous-silica chromatographic particles. Porous silica provides sufficient surface area within a confocal probe volume centered in an individual particle to readily measure, with Raman microscopy, the formation of an ordered hybrid bilayer of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) with the surface C18 chains. The DMPC surface density was quantified from the relative Raman scattering intensities of C18 and phospholipid acyl chains and found to be ∼40% of a DMPC vesicle membrane. By monitoring Raman spectra acquired versus temperature, the bilayer main phase transition was observed to be broadened and shifted to higher temperature compared to a DMPC vesicle, in agreement with differential scanning calorimetry (DSC) results. Raman scattering of deuterated phospholipid was resolved from protonated C18 chain scattering, showing that the lipid acyl and C18 chains melt simultaneously in a single phase transition. The surface density of lipid in the hybrid bilayer, the ordering of both C18 and lipid acyl chains upon bilayer formation, and decoupling of C18 methylene C-H vibrations by deuterated lipid acyl chains all suggest an interdigitated acyl chain

  1. Hybrid simulation of energetic particle effects on tearing modes in tokamak plasmas

    SciTech Connect

    Cai Huishan; Fu Guoyong

    2012-07-15

    The effects of energetic ions on stability of tearing mode are investigated by global kinetic/MHD hybrid simulations in a low beta tokamak plasma. The kinetic effects of counter circulating energetic ions from the non-adiabatic response are found to be strongly destabilizing while the effects from the adiabatic response are stabilizing. The net effect with both adiabatic and non-adiabatic contributions is destabilizing. On the other hand, the kinetic effects of co-circulating energetic ions from the non-adiabatic response are calculated to be weakly stabilizing while the corresponding adiabatic contribution is destabilizing for small energetic ion beta. The net effect is weakly stabilizing. The dependence of kinetic effects on energetic ion beta, gyroradius, and speed is studied systematically and the results agree in large part with the previous analytic results for the kinetic effects of circulating particles. For trapped energetic ions, their effects on tearing mode stability are dominated by the adiabatic response due to large banana orbit width and strong poloidal variation of particle pressure. The net effect of trapped energetic particles on tearing modes is much more destabilizing as compared to that of counter circulating particles at the same beta value.

  2. Discrete Diffusion Monte Carlo for grey Implicit Monte Carlo simulations.

    SciTech Connect

    Densmore, J. D.; Urbatsch, T. J.; Evans, T. M.; Buksas, M. W.

    2005-01-01

    Discrete Diffusion Monte Carlo (DDMC) is a hybrid transport-diffusion method for Monte Carlo simulations in diffusive media. In DDMC, particles take discrete steps between spatial cells according to a discretized diffusion equation. Thus, DDMC produces accurate solutions while increasing the efficiency of the Monte Carlo calculation. In this paper, we extend previously developed DDMC techniques in several ways that improve the accuracy and utility of DDMC for grey Implicit Monte Carlo calculations. First, we employ a diffusion equation that is discretized in space but is continuous time. Not only is this methodology theoretically more accurate than temporally discretized DDMC techniques, but it also has the benefit that a particle's time is always known. Thus, there is no ambiguity regarding what time to assign a particle that leaves an optically thick region (where DDMC is used) and begins transporting by standard Monte Carlo in an optically thin region. In addition, we treat particles incident on an optically thick region using the asymptotic diffusion-limit boundary condition. This interface technique can produce accurate solutions even if the incident particles are distributed anisotropically in angle. Finally, we develop a method for estimating radiation momentum deposition during the DDMC simulation. With a set of numerical examples, we demonstrate the accuracy and efficiency of our improved DDMC method.

  3. Center for Gyrokinetic/MHD Hybrid Simulation of Energetic Particle Physics in Toroidal Plasmas (CSEPP). Final report

    SciTech Connect

    Chen, Yang

    2012-03-07

    At Colorado University-Boulder the primary task is to extend our gyrokinetic Particle-in-Cell simulation of tokamak micro-turbulence and transport to the area of energetic particle physics. We have implemented a gyrokinetic ion/massless fluid electron hybrid model in the global {delta} f-PIC code GEM, and benchmarked the code with analytic results on the thermal ion radiative damping rate of Toroidal Alfven Eigenmodes (TAE) and with mode frequency and spatial structure from eigenmode analysis. We also performed nonlinear simulations of both a single-n mode (n is the toroidal mode number) and multiple-n modes, and in the case of single-n, benchmarked the code on the saturation amplitude vs. particle collision rate with analytical theory. Most simulations use the f method for both ions species, but we have explored the full-f method for energetic particles in cases where the burst amplitude of the excited instabilities is large as to cause significant re-distribution or loss of the energetic particles. We used the hybrid model to study the stability of high-n TAEs in ITER. Our simulations show that the most unstable modes in ITER lie in the rage of 10 < n < 20. Thermal ion pressure effect and alpha particles non-perturbative effect are important in determining the mode radial location and stability threshold. The thermal ion Landau damping rate and radiative damping rate from the simulations are compared with analytical estimates. The thermal ion Landau damping is the dominant damping mechanism. Plasma elongation has a strong stabilizing effect on the alpha driven TAEs. The central alpha particle pressure threshold for the most unstable n=15 mode is about {beta}{sub {alpha}}(0) = 0.7% for the fully shaped ITER equilibrium. We also carried nonlinear simulations of the most unstable n = 15 mode and found that the saturation amplitude for the nominal ITER discharge is too low to cause large redistribution or loss of alpha particles. To include kinetic electron effects

  4. Single-Particle Cryo-EM and 3D Reconstruction of Hybrid Nanoparticles with Electron-Dense Components.

    PubMed

    Yu, Guimei; Yan, Rui; Zhang, Chuan; Mao, Chengde; Jiang, Wen

    2015-10-01

    Single-particle cryo-electron microscopy (cryo-EM), accompanied with 3D reconstruction, is a broadly applicable tool for the structural characterization of macromolecules and nanoparticles. Recently, the cryo-EM field has pushed the limits of this technique to higher resolutions and samples of smaller molecular mass, however, some samples still present hurdles to this technique. Hybrid particles with electron-dense components, which have been studied using single-particle cryo-EM yet with limited success in 3D reconstruction due to the interference caused by electron-dense elements, constitute one group of such challenging samples. To process such hybrid particles, a masking method is developed in this work to adaptively remove pixels arising from electron-dense portions in individual projection images while maintaining maximal biomass signals for subsequent 2D alignment, 3D reconstruction, and iterative refinements. As demonstrated by the success in 3D reconstruction of an octahedron DNA/gold hybrid particle, which has been previously published without a 3D reconstruction, the devised strategy that combines adaptive masking and standard single-particle 3D reconstruction approach has overcome the hurdle of electron-dense elements interference, and is generally applicable to cryo-EM structural characterization of most, if not all, hybrid nanomaterials with electron-dense components.

  5. Influence of particles on the loading capacity and the temperature rise of water film in Ultra-high speed hybrid bearing

    NASA Astrophysics Data System (ADS)

    Zhu, Aibin; Li, Pei; Zhang, Yefan; Chen, Wei; Yuan, Xiaoyang

    2015-04-01

    Ultra-high speed machining technology enables high efficiency, high precision and high integrity of machined surface. Previous researches of hybrid bearing rarely consider influences of solid particles in lubricant and ultra-high speed of hybrid bearing, which cannot be ignored under the high speed and micro-space conditions of ultra-high speed water-lubricated hybrid bearing. Considering the impact of solid particles in lubricant, turbulence and temperature viscosity effects of lubricant, the influences of particles on pressure distribution, loading capacity and the temperature rise of the lubricant film with four-step-cavity ultra-high speed water-lubricated hybrid bearing are presented in the paper. The results show that loading capacity of the hybrid bearing can be affected by changing the viscosity of the lubricant, and large particles can improve the bearing loading capacity higher. The impact of water film temperature rise produced by solid particles in lubricant is related with particle diameter and minimum film thickness. Compared with the soft particles, hard particles cause the more increasing of water film temperature rise and loading capacity. When the speed of hybrid bearing increases, the impact of solid particles on hybrid bearing becomes increasingly apparent, especially for ultra-high speed water-lubricated hybrid bearing. This research presents influences of solid particles on the loading capacity and the temperature rise of water film in ultra-high speed hybrid bearings, the research conclusions provide a new method to evaluate the influence of solid particles in lubricant of ultra-high speed water-lubricated hybrid bearing, which is important to performance calculation of ultra-high speed hybrid bearings, design of filtration system, and safe operation of ultra-high speed hybrid bearings.

  6. Hybrid Gas Sensing and Transport Properties of Few-Walled CNTs Decorated with Discrete SnO₂ Nanoparticles.

    PubMed

    Ranganathan, Kamalakannan; Shanmugam, Ilango; Kamruddin, Mohammed; Tyagi, Ashok K

    2016-01-01

    CVD grown, few walled carbon nanotubes (FWCNTs) were quasi decorated with SnO₂nanoparticles (FWCNTs-SnO₂) and its gas sensing properties were analyzed with ammonia and ethanol. At room temperature FWCNTs-SnO₂show enhanced 'p type' gas sensing response than FWCNTs. Activation of SnO₂at high temperatures led to systematic changes in the sensing behavior towards 'n type' response. Temperature dependent transport behavior was found to be a one dimensional variable range hopping mechanism (1 D-VRH) for the FWCNTs and a 3D-VRH mechanism for the FWCNTs-SnO2. These temperature dependent gas transport and sensing properties elucidate the hybrid nature of the nanocomposite with novel characteristics. This also implies its importance as a potential gas sensor material. PMID:27398589

  7. Exact Hybrid Particle/Population Simulation of Rule-Based Models of Biochemical Systems

    PubMed Central

    Stover, Lori J.; Nair, Niketh S.; Faeder, James R.

    2014-01-01

    Detailed modeling and simulation of biochemical systems is complicated by the problem of combinatorial complexity, an explosion in the number of species and reactions due to myriad protein-protein interactions and post-translational modifications. Rule-based modeling overcomes this problem by representing molecules as structured objects and encoding their interactions as pattern-based rules. This greatly simplifies the process of model specification, avoiding the tedious and error prone task of manually enumerating all species and reactions that can potentially exist in a system. From a simulation perspective, rule-based models can be expanded algorithmically into fully-enumerated reaction networks and simulated using a variety of network-based simulation methods, such as ordinary differential equations or Gillespie's algorithm, provided that the network is not exceedingly large. Alternatively, rule-based models can be simulated directly using particle-based kinetic Monte Carlo methods. This “network-free” approach produces exact stochastic trajectories with a computational cost that is independent of network size. However, memory and run time costs increase with the number of particles, limiting the size of system that can be feasibly simulated. Here, we present a hybrid particle/population simulation method that combines the best attributes of both the network-based and network-free approaches. The method takes as input a rule-based model and a user-specified subset of species to treat as population variables rather than as particles. The model is then transformed by a process of “partial network expansion” into a dynamically equivalent form that can be simulated using a population-adapted network-free simulator. The transformation method has been implemented within the open-source rule-based modeling platform BioNetGen, and resulting hybrid models can be simulated using the particle-based simulator NFsim. Performance tests show that significant memory

  8. Quercetin conjugated silica particles as novel biofunctional hybrid materials for biological applications.

    PubMed

    Vergara-Castañeda, Hayde; Hernandez-Martinez, Angel R; Estevez, Miriam; Mendoza, Sandra; Luna-Barcenas, Gabriel; Pool, Héctor

    2016-03-15

    The aim of this work is to formulate biofunctional hybrid materials (HMs) with quercetin (QC) and silica particles (SiPs) by simple methods such as sol-gel and QC conjugation. Physicochemical characterization included particle size, zeta potential (ζ), FTIR and SEM imaging. Spherical particles with ca. 115 nm in diameter were produced, ζ and FTIR demonstrated that QC conjugation was successfully achieved. Electrochemical analyses performed by cyclic voltammetry (CV) suggested that potential binding sites between QC and SiPs may be at functional groups from A ring or C ring, affecting the transfer electron of resorcinol moiety. Iron chelating activity and lipid peroxidation assays showed that after conjugation to SiPs, QC decreased its metal chelating activity, but anti-radical properties is maintained. Our results demonstrated that our proposed method is simple and effective to obtain bio-functional HMs. Our findings prove to be useful in the design of protective approaches against lipid oxidation in food, pharmaceutical, and cosmetics fields. PMID:26704475

  9. Study of the absorption coefficient of alpha particles to lower hybrid waves in tokamak

    SciTech Connect

    Wang, Jianbing Zhang, Xianmei Yu, Limin Zhao, Xiang

    2014-02-12

    Part of the energy of the Lower Hybrid (LH) waves may be absorbed by the α particles via the so-called perpendicular landau damping mechanism, which depends on various parameters of fusion reactors and the LH waves. In this article, we calculate the absorption coefficient γ{sub α} of LH waves due to α particles. Results show that, the γ{sub α} increases with the parallel refraction index n{sub ∥} while deceases with increasing the frequency of LH waves ω{sub LH} over a wide range. Higher background plasma temperature and toroidal magnetic field will increase the absorption, and there is a peak value of γ{sub α} when n{sub e}≈8×10{sup 19}m{sup −3} for ITER-like scenario. The thermal corrections to the cold plasma dispersion relation will change the damping rate to a certain extent under some specific conditions. We have also evaluated the fraction of LH power absorbed by the alpha particles, η ≈ 0.47% and 4.1% for an LH frequency of 5 GHz and 3.7 GHz respectively for ITER-like scenario. This work gives the effective reference for the choice of parameters of future fusion reactors.

  10. LDRD final report : on the development of hybrid level-set/particle methods for modeling surface evolution during feature-scale etching and deposition processes.

    SciTech Connect

    McBride, Cory L.; Schmidt, Rodney Cannon; Musson, Lawrence Cale

    2005-01-01

    Two methods for creating a hybrid level-set (LS)/particle method for modeling surface evolution during feature-scale etching and deposition processes are developed and tested. The first method supplements the LS method by introducing Lagrangian marker points in regions of high curvature. Once both the particle set and the LS function are advanced in time, minimization of certain objective functions adjusts the LS function so that its zero contour is in closer alignment with the particle locations. It was found that the objective-minimization problem was unexpectedly difficult to solve, and even when a solution could be found, the acquisition of it proved more costly than simply expanding the basis set of the LS function. The second method explored is a novel explicit marker-particle method that we have named the grid point particle (GPP) approach. Although not a LS method, the GPP approach has strong procedural similarities to certain aspects of the LS approach. A key aspect of the method is a surface rediscretization procedure--applied at each time step and based on a global background mesh--that maintains a representation of the surface while naturally adding and subtracting surface discretization points as the surface evolves in time. This method was coded in 2-D, and tested on a variety of surface evolution problems by using it in the ChISELS computer code. Results shown for 2-D problems illustrate the effectiveness of the method and highlight some notable advantages in accuracy over the LS method. Generalizing the method to 3D is discussed but not implemented.

  11. Directed assembly of discrete gold nanoparticle groupings usingbranched DNA scaffolds

    SciTech Connect

    Claridge, Shelley A.; Goh, Sarah L.; Frechet, Jean M.J.; Williams, Shara C.; Micheel, Christine M.; Alivisatos, A. Paul

    2004-09-14

    The concept of self-assembled dendrimers is explored for the creation of discrete nanoparticle assemblies. Hybridization of branched DNA trimers and nanoparticle-DNA conjugates results in the synthesis of nanoparticle trimer and tetramer complexes. Multiple tetramer architectures are investigated, utilizing Au-DNA conjugates with varying secondary structural motifs. Hybridization products are analyzed by gel electrophoresis, and discrete bands are observed corresponding to structures with increasing numbers of hybridization events. Samples extracted from each band are analyzed by transmission electron microscopy, and statistics compiled from micrographs are used to compare assembly characteristics for each architecture. Asymmetric structures are also produced in which both 5 and 10 nm Au particles are assembled on branched scaffolds.

  12. Global particle simulation of lower hybrid wave propagation and mode conversion in tokamaks

    SciTech Connect

    Bao, J.; Lin, Z.; Kuley, A.

    2015-12-10

    Particle-in-cell simulation of lower hybrid (LH) waves in core plasmas is presented with a realistic electron-to-ion mass ratio in toroidal geometry. Due to the fact that LH waves mainly interact with electrons to drive the current, ion dynamic is described by cold fluid equations for simplicity, while electron dynamic is described by drift kinetic equations. This model could be considered as a new method to study LH waves in tokamak plasmas, which has advantages in nonlinear simulations. The mode conversion between slow and fast waves is observed in the simulation when the accessibility condition is not satisfied, which is consistent with the theory. The poloidal spectrum upshift and broadening effects are observed during LH wave propagation in the toroidal geometry.

  13. Hybrid Particle Code Simulations of Mars: The Role Ionospheric Escape in Explaining Water Loss from Mars

    NASA Astrophysics Data System (ADS)

    Brecht, Stephen; Ledvina, Stephen

    2015-11-01

    The results of our latest hybrid particle simulations using the HALFSHEL code are discussed. The presentation will address assorted processes that produce differing ion escape rates from Mars. The simulations investigate the role of the neutral atmosphere (Univ. of Michigan's MTGCM) in its dynamic form (neutral winds and co-rotation) in the calculation of the ionospheric loss from Mars. In addition, the effect of crustal magnetic field orientation in ion escape from Mars will be discussed. Further, the presentation addresses reasons for these differences and details of the interaction around the crustal magnetic fields. Finally, these results and others will be compared to fits to data. The estimated loss rates from a variety of missions and times were fit to the solar EUV flux. Our results will be compared to this fit.

  14. Application of Positron Emission Particle Tracking (PEPT) to validate a Discrete Element Method (DEM) model of granular flow and mixing in the Turbula mixer.

    PubMed

    Marigo, M; Davies, M; Leadbeater, T; Cairns, D L; Ingram, A; Stitt, E H

    2013-03-25

    The laboratory-scale Turbula mixer comprises a simple cylindrical vessel that moves with a complex, yet periodic 3D motion comprising of rotation, translation and inversion. Arising from this complexity, relatively few studies to obtain fundamental understanding of particle motion and mixing mechanisms have been reported. Particle motion within a cylindrical vessel of a Turbula mixer has been measured for 2mm glass spheres using Positron Emission Particle Tracking (PEPT) in a 2l blending mixing vessel at 50% fill level. These data are compared to results from Discrete Element Method (DEM) simulations previously published by the authors. PEPT mixing experiments, using a single particle tracer, gave qualitatively similar trends to the DEM predictions for axial and radial dispersion as well as for the axial displacement statistics at different operational speeds. Both experimental and simulation results indicate a minimum mixing efficiency at ca. 46 rpm. The occupancy plots also show a non-linear relationship with the operating speed. These results add further evidence to a transition between two flow and mixing regimes. Despite the similarity in overall flow and mixing behaviour measured and predicted, including the mixing speed at which the flow behaviour transition occurs, a systematic offset between measured and predicted result is observed. PMID:23376506

  15. Shape Analysis of DNA-Au Hybrid Particles by Analytical Ultracentrifugation.

    PubMed

    Urban, Maximilan J; Holder, Isabelle T; Schmid, Marius; Fernandez Espin, Vanesa; Garcia de la Torre, Jose; Hartig, Jörg S; Cölfen, Helmut

    2016-08-23

    Current developments in nanotechnology have increased the demand for nanocrystal assemblies with well-defined shapes and tunable sizes. DNA is a particularly well-suited building block in nanoscale assemblies because of its scalable sizes, conformational variability, and convenient self-assembly capabilities via base pairing. In hybrid materials, gold nanoparticles (AuNPs) can be assembled into nanoparticle structures with programmable interparticle distances by applying appropriate DNA sequences. However, the development of stoichiometrically defined DNA/NP structures is still challenging since product mixtures are frequently obtained and their purification and characterization is the rate-limiting step in the development of DNA-NP hybrid assemblies. Improvements in nanostructure fractionation and characterization techniques offer great potential for nanotechnology applications in general. This study reports the application of analytical ultracentrifugation (AUC) for the characterization of anisotropic DNA-linked metal-crystal assemblies. On the basis of transmission electron microscopy data and the DNA primary sequence, hydrodynamic bead models are set up for the interpretation of the measured frictional ratios and sedimentation coefficients. We demonstrate that the presence of single DNA strands on particle surfaces as well as the shape factors of multiparticle structures in mixtures can be quantitatively described by AUC. This study will significantly broaden the possibilities to analyze mixtures of shape-anisotropic nanoparticle assemblies. By establishing insights into the analysis of nanostructure mixtures based on fundamental principles of sedimentation, a wide range of potential applications in basic research and industry become accessible. PMID:27459174

  16. Extension and Validation of a Hybrid Particle-Finite Element Method for Hypervelocity Impact Simulation. Chapter 2

    NASA Technical Reports Server (NTRS)

    Fahrenthold, Eric P.; Shivarama, Ravishankar

    2004-01-01

    The hybrid particle-finite element method of Fahrenthold and Horban, developed for the simulation of hypervelocity impact problems, has been extended to include new formulations of the particle-element kinematics, additional constitutive models, and an improved numerical implementation. The extended formulation has been validated in three dimensional simulations of published impact experiments. The test cases demonstrate good agreement with experiment, good parallel speedup, and numerical convergence of the simulation results.

  17. Lower hybrid instability driven by mono-energy {alpha}-particles with finite pitch angle spread in a plasma

    SciTech Connect

    Kumar, Pawan; Singh, Vishwesh; Tripathi, V. K.

    2013-02-15

    A kinetic formalism of lower hybrid wave instability, driven by mono-energy {alpha}-particles with finite pitch angle spread, is developed. The instability arises through cyclotron resonance interaction with high cyclotron harmonics of {alpha}-particles. The {alpha}-particles produced in D-T fusion reactions have huge Larmor radii ({approx}10 cm) as compared to the wavelength of the lower hybrid wave, whereas their speed is an order of magnitude smaller than the speed of light in vacuum. As a result, large parallel phase velocity lower hybrid waves, suitable for current drive in tokamak, are driven unstable via coupling to high cyclotron harmonics. The growth rate decreases with increase in pitch angle spread of the beam. At typical electron density of {approx}10{sup 19} m{sup -3}, magnetic field {approx}4 Tesla and {alpha}-particle concentration {approx}0.1%, the large parallel phase velocity lower hybrid wave grows on the time scale of 20 ion cyclotron periods. The growth rate decreases with plasma density.

  18. Lower hybrid instability driven by mono-energy α-particles with finite pitch angle spread in a plasma

    NASA Astrophysics Data System (ADS)

    Kumar, Pawan; Singh, Vishwesh; Tripathi, V. K.

    2013-02-01

    A kinetic formalism of lower hybrid wave instability, driven by mono-energy α-particles with finite pitch angle spread, is developed. The instability arises through cyclotron resonance interaction with high cyclotron harmonics of α-particles. The α-particles produced in D-T fusion reactions have huge Larmor radii (˜10 cm) as compared to the wavelength of the lower hybrid wave, whereas their speed is an order of magnitude smaller than the speed of light in vacuum. As a result, large parallel phase velocity lower hybrid waves, suitable for current drive in tokamak, are driven unstable via coupling to high cyclotron harmonics. The growth rate decreases with increase in pitch angle spread of the beam. At typical electron density of ˜1019 m-3, magnetic field ˜4 Tesla and α-particle concentration ˜0.1%, the large parallel phase velocity lower hybrid wave grows on the time scale of 20 ion cyclotron periods. The growth rate decreases with plasma density.

  19. New hybrid genetic particle swarm optimization algorithm to design multi-zone binary filter.

    PubMed

    Lin, Jie; Zhao, Hongyang; Ma, Yuan; Tan, Jiubin; Jin, Peng

    2016-05-16

    The binary phase filters have been used to achieve an optical needle with small lateral size. Designing a binary phase filter is still a scientific challenge in such fields. In this paper, a hybrid genetic particle swarm optimization (HGPSO) algorithm is proposed to design the binary phase filter. The HGPSO algorithm includes self-adaptive parameters, recombination and mutation operations that originated from the genetic algorithm. Based on the benchmark test, the HGPSO algorithm has achieved global optimization and fast convergence. In an easy-to-perform optimizing procedure, the iteration number of HGPSO is decreased to about a quarter of the original particle swarm optimization process. A multi-zone binary phase filter is designed by using the HGPSO. The long depth of focus and high resolution are achieved simultaneously, where the depth of focus and focal spot transverse size are 6.05λ and 0.41λ, respectively. Therefore, the proposed HGPSO can be applied to the optimization of filter with multiple parameters. PMID:27409895

  20. Particle-in-cell simulation study of a lower-hybrid shock

    NASA Astrophysics Data System (ADS)

    Dieckmann, M. E.; Sarri, G.; Doria, D.; Ynnerman, A.; Borghesi, M.

    2016-06-01

    The expansion of a magnetized high-pressure plasma into a low-pressure ambient medium is examined with particle-in-cell simulations. The magnetic field points perpendicular to the plasma's expansion direction and binary collisions between particles are absent. The expanding plasma steepens into a quasi-electrostatic shock that is sustained by the lower-hybrid (LH) wave. The ambipolar electric field points in the expansion direction and it induces together with the background magnetic field a fast E cross B drift of electrons. The drifting electrons modify the background magnetic field, resulting in its pile-up by the LH shock. The magnetic pressure gradient force accelerates the ambient ions ahead of the LH shock, reducing the relative velocity between the ambient plasma and the LH shock to about the phase speed of the shocked LH wave, transforming the LH shock into a nonlinear LH wave. The oscillations of the electrostatic potential have a larger amplitude and wavelength in the magnetized plasma than in an unmagnetized one with otherwise identical conditions. The energy loss to the drifting electrons leads to a noticeable slowdown of the LH shock compared to that in an unmagnetized plasma.

  1. The detection of minimum ionizing particles with scintillating fibers using multi-pixel hybrid photodiodes

    SciTech Connect

    Datema, C.P.; Meng, L.J.; Ramsden, D.

    1998-06-01

    Recent measurements of the performance of the newly available multi-pixel Hybrid Photodiode (M-HPD) have demonstrated their particular value in the detection of very low light-level signals in the visible region. The single and multiple photo-electron response characteristics of these devices is unmatched by any other room-temperature device. This characteristic, coupled with their speed of response and the availability of an internally-generated trigger signal when one or more of the pixels detect an event, makes them particularly interesting as possible photo-detectors for fast plastic scintillators and, in particular, as detectors for reading out scintillating fibers. The results of tests made when Minimum Ionizing Particles (MIPs) pass through single and multi-clad plastic scintillating fibers have confirmed the usefulness of these devices in particle-tracking applications. The technique used to read-out 61 channels of data is described along with a way to view as many as 2,000 fibers with just two 61-pixel M-HPDs.

  2. High rate particle tracking and ultra-fast timing with a thin hybrid silicon pixel detector

    NASA Astrophysics Data System (ADS)

    Fiorini, M.; Aglieri Rinella, G.; Carassiti, V.; Ceccucci, A.; Cortina Gil, E.; Cotta Ramusino, A.; Dellacasa, G.; Garbolino, S.; Jarron, P.; Kaplon, J.; Kluge, A.; Marchetto, F.; Mapelli, A.; Martin, E.; Mazza, G.; Morel, M.; Noy, M.; Nuessle, G.; Perktold, L.; Petagna, P.; Petrucci, F.; Poltorak, K.; Riedler, P.; Rivetti, A.; Statera, M.; Velghe, B.

    2013-08-01

    The Gigatracker (GTK) is a hybrid silicon pixel detector designed for the NA62 experiment at CERN. The beam spectrometer, made of three GTK stations, has to sustain high and non-uniform particle rate (∼ 1 GHz in total) and measure momentum and angles of each beam track with a combined time resolution of 150 ps. In order to reduce multiple scattering and hadronic interactions of beam particles, the material budget of a single GTK station has been fixed to 0.5% X0. The expected fluence for 100 days of running is 2 ×1014 1 MeV neq /cm2, comparable to the one foreseen in the inner trackers of LHC detectors during 10 years of operation. To comply with these requirements, an efficient and very low-mass (< 0.15 %X0) cooling system is being constructed, using a novel microchannel cooling silicon plate. Two complementary read-out architectures have been produced as small-scale prototypes: one is based on a Time-over-Threshold circuit followed by a TDC shared by a group of pixels, while the other makes use of a constant-fraction discriminator followed by an on-pixel TDC. The read-out ASICs are produced in 130 nm IBM CMOS technology and will be thinned down to 100 μm or less. An overview of the Gigatracker detector system will be presented. Experimental results from laboratory and beam tests of prototype bump-bonded assemblies will be described as well. These results show a time resolution of about 170 ps for single hits from minimum ionizing particles, using 200 μm thick silicon sensors.

  3. Preparation of double emulsions using hybrid polymer/silica particles: new pickering emulsifiers with adjustable surface wettability.

    PubMed

    Williams, Mark; Warren, Nicholas J; Fielding, Lee A; Armes, Steven P; Verstraete, Pierre; Smets, Johan

    2014-12-10

    A facile route for the preparation of water-in-oil-in-water (w/o/w) double emulsions is described for three model oils, namely, n-dodecane, isopropyl myristate, and isononyl isononanoate, using fumed silica particles coated with poly(ethylene imine) (PEI). The surface wettability of such hybrid PEI/silica particles can be systematically adjusted by (i) increasing the adsorbed amount of PEI and (ii) addition of 1-undecanal to the oil phase prior to homogenization. In the absence of this long-chain aldehyde, PEI/silica hybrid particles (PEI/silica mass ratio = 0.50) produce o/w Pickering emulsions in all cases. In the presence of 1-undecanal, this reagent reacts with the primary and secondary amine groups on the PEI chains via Schiff base chemistry, which can render the PEI/silica hybrid particles sufficiently hydrophobic to stabilize w/o Pickering emulsions at 20 °C. Gas chromatography, (1)H NMR and X-ray photoelectron spectroscopy provide compelling experimental evidence for this in situ surface reaction, while a significant increase in the water contact angle indicates markedly greater hydrophobic character for the PEI/silica hybrid particles. However, when PEI/silica hybrid particles are prepared using a relatively low adsorbed amount of PEI (PEI/silica mass ratio = 0.075) only o/w Pickering emulsions are obtained, since the extent of surface modification achieved using this Schiff base chemistry is insufficient. Fluorescence microscopy and laser diffraction studies confirm that highly stable w/o/w double emulsions can be achieved for all three model oils. This is achieved by first homogenizing the relatively hydrophobic PEI/silica hybrid particles (PEI/silica mass ratio = 0.50) with an oil containing 3% 1-undecanal to form an initial w/o emulsion, followed by further homogenization using an aqueous dispersion of relatively hydrophilic PEI/silica particles (PEI/silica mass ratio = 0.075). Dye release from the internal aqueous cores into the aqueous continuous

  4. Global Hybrid Simulations of Energetic Particle Effects on the n=1 Mode in Tokamaks: Internal Kink and Fishbone Instability

    SciTech Connect

    G.Y. Fu; W. Park; H.R. Strauss; J. Breslau; J. Chen; S. Jardin; L.E. Sugiyama

    2005-08-09

    Global hybrid simulations of energetic particle effects on the n=1 internal kink mode have been carried out for tokamaks. For the International Thermonuclear Experimental Reactor (ITER) [ITER Physics Basis Editors et al., Nucl. Fusion 39:2137 (1999)], it is shown that alpha particle effects are stabilizing for the internal kink mode. However, the elongation of ITER reduces the stabilization effects significantly. Nonlinear simulations of the precessional drift fishbone instability for circular tokamak plasmas show that the mode saturates due to flattening of the particle distribution function near the resonance region. The mode frequency chirps down rapidly as the flattening region expands radially outward. Fluid nonlinearity reduces the saturation level.

  5. Spectrograph of charged particles consisting of a discrete plane electrode with different potential distributions and a grounded box-shaped electrode

    NASA Astrophysics Data System (ADS)

    Fishkova, T. Ya.

    2015-06-01

    A simple two-electrode spectrograph that has been proposed by the author for fast analysis of the beams of charged particles with respect to energy is theoretically studied. A specific feature of such a spectrograph lies in the fact that the system makes it possible to apply different potentials to fragments of the split plane electrode. Computer simulation is used to determine the optimal working regimes of the spectrograph in which the range of simultaneously measured energies of the beams that are focused on one line increases with a decrease in the growth rate of potentials at the discrete plane electrode and amounts to a maximum known level of two orders of magnitude.

  6. Production of Hybrid Chimeric PVX Particles Using a Combination of TMV and PVX-Based Expression Vectors

    PubMed Central

    Dickmeis, Christina; Honickel, Mareike Michaela Antonia; Fischer, Rainer; Commandeur, Ulrich

    2015-01-01

    We have generated hybrid chimeric potato virus X (PVX) particles by coexpression of different PVX coat protein fusions utilizing tobacco mosaic virus (TMV) and PVX-based expression vectors. Coinfection was achieved with a modified PVX overcoat vector displaying a fluorescent protein and a TMV vector expressing another PVX fluorescent overcoat fusion protein. Coexpression of the PVX-CP fusions in the same cells was confirmed by epifluorescence microscopy. Labeling with specific antibodies and transmission electron microscopy revealed chimeric particles displaying green fluorescent protein and mCherry on the surface. These data were corroborated by bimolecular fluorescence complementation. We used split-mCherry fragments as PVX coat fusions and confirmed an interaction between the split-mCherry fragments in coinfected cells. The presence of assembled split-mCherry on the surface confirmed the hybrid character of the chimeric particles. PMID:26636076

  7. Production of Hybrid Chimeric PVX Particles Using a Combination of TMV and PVX-Based Expression Vectors.

    PubMed

    Dickmeis, Christina; Honickel, Mareike Michaela Antonia; Fischer, Rainer; Commandeur, Ulrich

    2015-01-01

    We have generated hybrid chimeric potato virus X (PVX) particles by coexpression of different PVX coat protein fusions utilizing tobacco mosaic virus (TMV) and PVX-based expression vectors. Coinfection was achieved with a modified PVX overcoat vector displaying a fluorescent protein and a TMV vector expressing another PVX fluorescent overcoat fusion protein. Coexpression of the PVX-CP fusions in the same cells was confirmed by epifluorescence microscopy. Labeling with specific antibodies and transmission electron microscopy revealed chimeric particles displaying green fluorescent protein and mCherry on the surface. These data were corroborated by bimolecular fluorescence complementation. We used split-mCherry fragments as PVX coat fusions and confirmed an interaction between the split-mCherry fragments in coinfected cells. The presence of assembled split-mCherry on the surface confirmed the hybrid character of the chimeric particles. PMID:26636076

  8. Red-blood-cell-like BSA/Zn3(PO4)2 hybrid particles: Preparation and application to adsorption of heavy metal ions

    NASA Astrophysics Data System (ADS)

    Zhang, Baoliang; Li, Peitao; Zhang, Hepeng; Li, Xiangjie; Tian, Lei; Wang, Hai; Chen, Xin; Ali, Nisar; Ali, Zafar; Zhang, Qiuyu

    2016-03-01

    A novel kind of red-blood-cell-like bovine serum albumin (BSA)/Zn3(PO4)2 hybrid particle is prepared at room temperature by a facile and rapid one-step method based on coordination between BSA and zinc ion. The morphology of the monodisperse hybrid particle shows oblate spheroidal type with a one sided single hole on the surface. The hybrid particle is constructed with BSA/Zn3(PO4)2 nanoplates of 35 nm thick. The average particle size of hybrid particle is 2.3 μm, and its BET specific surface area is 146.64 cm2/g. To clarify the evolution of BSA/Zn3(PO4)2 hybrid particle, SEM and elemental analysis as a function of particle growth time are investigated. The formation mechanism of BSA/Zn3(PO4)2 hybrid particle, which can be described as crystallization, coordination and self-assembly process, is illustrated in detail. The as-prepared BSA/Zn3(PO4)2 hybrid particle is used for adsorption of Cu2+. The hybrid particle displayed excellent adsorption properties on Cu2+. The adsorption efficiency of BSA/Zn3(PO4)2 hybrid particles at 5 min and 30 min are 86.33% and 98.9%, respectively. The maximum adsorption capacity is 6.85 mg/g. Thus, this kind of novel adsorbent shows potential application value in ultra-fast and highly efficient removal of Cu2+.

  9. Use of hybrid composite particles prepared using alkoxysilane-functionalized amphiphilic polymer precursors for simultaneous removal of various pollutants from water.

    PubMed

    Cho, Seulki; Kim, Nahae; Lee, Soonjae; Lee, Hoseok; Lee, Sang-Hyup; Kim, Juyoung; Choi, Jae-Woo

    2016-08-01

    In this study, we present new inorganic-organic hybrid particles and their possible application as an adsorbent for simultaneous removal of hydrophobic and hydrophilic pollutants from water. These hybrid particles were prepared using tailor-made alkoxysilane-functionalized amphiphilic polymer precursors (M-APAS), which have amphiphilic polymers and reactive alkoxysilane groups attached to the same backbone. Through a single conventional sol-gel process, the polymerization of M-APAS and the chemical conjugation of M-APAS onto silica nanoparticles was simultaneous, resulting in the formation of hybrid particles (M-APAS-SiO2) comprised of hyperbranch-like amphiphilic polymers bonded onto silica nanoparticles with a relatively high grafting efficiency. A test for the adsorption of water-soluble dye (organe-16) and water insoluble dye (solvent blue-35) onto the hybrid particles was performed to evaluate the possibility of adsorbing hydrophilic and hydrophobic compound within the same particle. The hybrid particle was also evaluated as an adsorbent for the removal of contaminated water containing various pollutants by wastewater treatment test. The hybrid particle could remove phenolic compounds from wastewater and the azo dye reactive orange-16 from aqueous solutions, and it was easily separated from the treated wastewater because of the different densities involved. These results demonstrate that the hybrid particles are a promising sorbent for hydrophilic and/or hydrophobic pollutants in water.

  10. The use of hybrid Virus-like Particles to enhance the immunogenicity of a broadly protective HPV vaccine

    PubMed Central

    Tyler, Mitchell; Tumban, Ebenezer; Peabody, David S.; Chackerian, Bryce

    2015-01-01

    Virus-like particles (VLPs) can serve as a highly immunogenic vaccine platform for the multivalent display of epitopes from pathogens. We have used bacteriophage VLPs to develop vaccines that target a highly conserved epitope from the Human Papillomavirus (HPV) minor capsid protein, L2. VLPs displaying an L2-peptide from HPV16 elicit antibodies that broadly neutralize infection by HPV types associated with the development of cervical cancer. To broaden the cross-neutralization further, we have developed a strategy to display two different peptides on a single, hybrid VLP in a multivalent, highly immunogenic fashion. In general, hybrid VLPs elicited high-titer antibody responses against both targets, although in one case we observed an immunodominant response against only one of the displayed epitopes. Immunization with hybrid particles elicited antibodies that were able to neutralize heterologous HPV types at higher titers than those elicited by particles displaying one epitope alone, indicating that the hybrid VLP approach may be an effective technique to target epitopes that undergo antigenic variation. PMID:24917327

  11. Effect of Silane Treatment on Hybridized Use of Short Cellulose Fibers and Silica Particles for Natural Rubber Reinforcement

    NASA Astrophysics Data System (ADS)

    Lopattananon, Natinee; Jitkalong, Dolmalik; Seadan, Manus; Sakai, Tadamoto

    Processability, swelling and tensile properties of natural-rubber-based hybrid composites prepared by mixing short cellulose fibers and fine silica particles of equal contents with total loading of 20 phr using a two-roll mill were analyzed. Their properties were compared with those of natural rubber reinforced with single filler (silica or cellulose fiber) and corresponding unfilled natural rubber. The tensile test showed the reinforcing effect of both single filler system and hybrid filler system in relation to natural rubber. The tensile modulus and tensile strength of hybrid composites generally laid between those of fiber-reinforced and silica-reinforced natural rubber composites, whereas the elongation at break of hybrid composites was equal to that of single filler reinforcement system. The Mooney viscosity of silica-filled compound was much higher than that of unfilled natural rubber and short fiber-filled compounds, and was significantly reduced when hybridized fillers were used. Furthermore, a silane coupling agent, Si 69, was used to modify the surface properties of cellulose fibers and silica particles. Three microscopic evaluation techniques, that is, elemental X-ray mapping (EDX), 3D microfocus X-ray scanning, and N-ARC methods were applied to investigate the filler dispersion/mixing effects. It was found that both of the fillers were more homogeneously dispersed in the hybrid composites, and the affinity between the fillers and natural rubber was improved after the silane treatment. The results from this work suggested that the better dispersion of short cellulose fiber/silica hybrid fillers had great advantages in rubber processing, and allowed for equal or higher composite strength compared to a simply silica-filled composite system.

  12. Results of an ISEE-1 experiment to study the interactions between energetic particles and discrete VLF waves in the magnetosphere

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Despite the malfunctioning of the digital portion of the experiment which is encoding the absolute amplitude of the wave spectrum with a fixed bias of approximately 20 dB, the analog portion of the instrument is acquiring excellent data concerning the wave function and relative amplitude. Results obtained over a 2-year period which have important implications for magnetospheric wave-particle interactions are examined in the areas of emission generation by nonconducted coherent waves, and cold plasma distribution in the inner magnetosphere.

  13. Preparation of Porous Chitosan-Siloxane Hybrids Coated with Hydroxyapatite Particles.

    PubMed

    Shirosaki, Yuki; Okamoto, Kohei; Hayakawa, Satoshi; Osaka, Akiyoshi; Asano, Takuji

    2015-01-01

    This paper describes the apatite deposition of chitosan-silicate porous hybrids derived from chitosan and γ-glycidoxypropyltrimethoxysilane (GPTMS) in alkaline phosphate solution. The preparation of porous hybrids with needle-like apatite on their surfaces is described. Following apatite deposition the porous hybrids maintained high porosity. The enzymatic degradation rate was low even after 6 months and the porous hybrids were very flexible and cut easily using surgical scissors.

  14. Efficient Scheduling of Scientific Workflows with Energy Reduction Using Novel Discrete Particle Swarm Optimization and Dynamic Voltage Scaling for Computational Grids.

    PubMed

    Christobel, M; Tamil Selvi, S; Benedict, Shajulin

    2015-01-01

    One of the most significant and the topmost parameters in the real world computing environment is energy. Minimizing energy imposes benefits like reduction in power consumption, decrease in cooling rates of the computing processors, provision of a green environment, and so forth. In fact, computation time and energy are directly proportional to each other and the minimization of computation time may yield a cost effective energy consumption. Proficient scheduling of Bag-of-Tasks in the grid environment ravages in minimum computation time. In this paper, a novel discrete particle swarm optimization (DPSO) algorithm based on the particle's best position (pbDPSO) and global best position (gbDPSO) is adopted to find the global optimal solution for higher dimensions. This novel DPSO yields better schedule with minimum computation time compared to Earliest Deadline First (EDF) and First Come First Serve (FCFS) algorithms which comparably reduces energy. Other scheduling parameters, such as job completion ratio and lateness, are also calculated and compared with EDF and FCFS. An energy improvement of up to 28% was obtained when Makespan Conservative Energy Reduction (MCER) and Dynamic Voltage Scaling (DVS) were used in the proposed DPSO algorithm. PMID:26075296

  15. Efficient Scheduling of Scientific Workflows with Energy Reduction Using Novel Discrete Particle Swarm Optimization and Dynamic Voltage Scaling for Computational Grids

    PubMed Central

    Christobel, M.; Tamil Selvi, S.; Benedict, Shajulin

    2015-01-01

    One of the most significant and the topmost parameters in the real world computing environment is energy. Minimizing energy imposes benefits like reduction in power consumption, decrease in cooling rates of the computing processors, provision of a green environment, and so forth. In fact, computation time and energy are directly proportional to each other and the minimization of computation time may yield a cost effective energy consumption. Proficient scheduling of Bag-of-Tasks in the grid environment ravages in minimum computation time. In this paper, a novel discrete particle swarm optimization (DPSO) algorithm based on the particle's best position (pbDPSO) and global best position (gbDPSO) is adopted to find the global optimal solution for higher dimensions. This novel DPSO yields better schedule with minimum computation time compared to Earliest Deadline First (EDF) and First Come First Serve (FCFS) algorithms which comparably reduces energy. Other scheduling parameters, such as job completion ratio and lateness, are also calculated and compared with EDF and FCFS. An energy improvement of up to 28% was obtained when Makespan Conservative Energy Reduction (MCER) and Dynamic Voltage Scaling (DVS) were used in the proposed DPSO algorithm. PMID:26075296

  16. a Hybrid Approach of Neural Network with Particle Swarm Optimization for Tobacco Pests Prediction

    NASA Astrophysics Data System (ADS)

    Lv, Jiake; Wang, Xuan; Xie, Deti; Wei, Chaofu

    Forecasting pests emergence levels plays a significant role in regional crop planting and management. The accuracy, which is derived from the accuracy of the forecasting approach used, will determine the economics of the operation of the pests prediction. Conventional methods including time series, regression analysis or ARMA model entail exogenous input together with a number of assumptions. The use of neural networks has been shown to be a cost-effective technique. But their training, usually with back-propagation algorithm or other gradient algorithms, is featured with some drawbacks such as very slow convergence and easy entrapment in a local minimum. This paper presents a hybrid approach of neural network with particle swarm optimization for developing the accuracy of predictions. The approach is applied to forecast Alternaria alternate Keissl emergence level of the WuLong Country, one of the most important tobacco planting areas in Chongqing. Traditional ARMA model and BP neural network are investigated as comparison basis. The experimental results show that the proposed approach can achieve better prediction performance.

  17. Modeling dynamic urban growth using hybrid cellular automata and particle swarm optimization

    NASA Astrophysics Data System (ADS)

    Rabbani, Amirhosein; Aghababaee, Hossein; Rajabi, Mohammad A.

    2012-01-01

    Conventional raster-based cellular automata (CA) confront many difficulties because of cell size and neighborhood sensitivity. Alternatively, vector CA-based models are very complex and difficult to implement. We present a hybrid cellular automata (HCA) model as a combination of cellular structure and vector concept. The space is still defined by a set of cells, but rasterized spatial objects are also utilized in the structure of transition rules. Particle swarm optimization (PSO) is also used to calculate the urbanization probability of cells based on their distance from the development parameters. The proposed model is applied to Landsat satellite imagery of the city of Tehran, Iran with 28.5-m spatial resolution to simulate the urban growth from 1988 to 2010. Statistical comparison of the ground truth and the simulated image using a kappa coefficient shows an accuracy of 83.42% in comparison to the 81.13% accuracy for the conventional Geo-CA model. Moreover, decreasing the spatial resolution by a factor of one-fourth has reduced the accuracy of the HCA and Geo-CA models by 1.19% and 3.04%, respectively, which shows the lower scale sensitivity of the proposed model. The HCA model is developed to have the simplicity of cellular structure together with optimum features of vector models.

  18. Hybrid Particle Code Simulations of Mars: The Role of Assorted Processes in Ionospheric Escape.

    NASA Astrophysics Data System (ADS)

    Brecht, S. H.; Ledvina, S. A.

    2014-12-01

    The results of our latest hybrid particle simulations using the HALFSHEL code are discussed. The presentation will address assorted processes that produce differing ion escape rates from Mars. The simulations investigate the role of the neutral atmosphere (Univ. of Michigan's MTGCM) in its dynamic form (neutral winds and co-rotation) in the calculation of the ionospheric loss from Mars. In addition, the effect of crustal magnetic field orientation in ion escape from Mars will be discussed. Further, the presentation addresses reasons for these differences and details of the interaction around the crustal magnetic fields. Finally, these results and others will be compared to fits to data produced by Lundin et al. [2013]. In the Lundin paper the estimated loss rates from a variety of missions and times were fit to the solar EUV flux. Our results will be compared to this fit. Lundin, R, S. Barabash, M. Holström, H. Nilsson, Y. Futaana, R. Ramstad, M. Ymauchi, E. Dubinin, and M. Fraenz (2013), "Solar cycle effects on the ion escape from Mars," Geophy. Res. Lett., 40, 6028-6032, doi:10.1002/2013GL058154.

  19. Particle filter based hybrid prognostics for health monitoring of uncertain systems in bond graph framework

    NASA Astrophysics Data System (ADS)

    Jha, Mayank Shekhar; Dauphin-Tanguy, G.; Ould-Bouamama, B.

    2016-06-01

    The paper's main objective is to address the problem of health monitoring of system parameters in Bond Graph (BG) modeling framework, by exploiting its structural and causal properties. The system in feedback control loop is considered uncertain globally. Parametric uncertainty is modeled in interval form. The system parameter is undergoing degradation (prognostic candidate) and its degradation model is assumed to be known a priori. The detection of degradation commencement is done in a passive manner which involves interval valued robust adaptive thresholds over the nominal part of the uncertain BG-derived interval valued analytical redundancy relations (I-ARRs). The latter forms an efficient diagnostic module. The prognostics problem is cast as joint state-parameter estimation problem, a hybrid prognostic approach, wherein the fault model is constructed by considering the statistical degradation model of the system parameter (prognostic candidate). The observation equation is constructed from nominal part of the I-ARR. Using particle filter (PF) algorithms; the estimation of state of health (state of prognostic candidate) and associated hidden time-varying degradation progression parameters is achieved in probabilistic terms. A simplified variance adaptation scheme is proposed. Associated uncertainties which arise out of noisy measurements, parametric degradation process, environmental conditions etc. are effectively managed by PF. This allows the production of effective predictions of the remaining useful life of the prognostic candidate with suitable confidence bounds. The effectiveness of the novel methodology is demonstrated through simulations and experiments on a mechatronic system.

  20. A fluid-particle hybrid framework for the PLUTO code: applications to non-thermal emission in jets.

    NASA Astrophysics Data System (ADS)

    Vaidya, B.; Mignone, A.; Bodo, G.; Massaglia, S.

    2016-05-01

    We present an implementation of a fully parallel hybrid framework for the evolution of Lagrangian particles coupled to a MHD fluid for the PLUTO code. For the applications of interest, particles represent ensembles of electrons whose spectral energy distribution is governed by a kinetic transport equation that takes into account different physical processes such as diffusive shock acceleration, synchrotron emission and adiabatic expansion. An application to model non-thermal emission from extragalactic jets shows the effectiveness and strength of the approach in describing not only the dynamics but also the radiation properties of jets and, in general, of high-energy astrophysical plasma environments.

  1. Thermo-mechanical characterization of siliconized E-glass fiber/hematite particles reinforced epoxy resin hybrid composite

    NASA Astrophysics Data System (ADS)

    V. R., Arun prakash; Rajadurai, A.

    2016-10-01

    In this present work hybrid polymer (epoxy) matrix composite has been strengthened with surface modified E-glass fiber and iron(III) oxide particles with varying size. The particle sizes of 200 nm and <100 nm has been prepared by high energy ball milling and sol-gel methods respectively. To enhance better dispersion of particles and improve adhesion of fibers and fillers with epoxy matrix surface modification process has been done on both fiber and filler by an amino functional silane 3-Aminopropyltrimethoxysilane (APTMS). Crystalline and functional groups of siliconized iron(III) oxide particles were characterized by XRD and FTIR spectroscopy analysis. Fixed quantity of surface treated 15 vol% E-glass fiber was laid along with 0.5 and 1.0 vol% of iron(III) oxide particles into the matrix to fabricate hybrid composites. The composites were cured by an aliphatic hardener Triethylenetetramine (TETA). Effectiveness of surface modified particles and fibers addition into the resin matrix were revealed by mechanical testing like tensile testing, flexural testing, impact testing, inter laminar shear strength and hardness. Thermal behavior of composites was evaluated by TGA, DSC and thermal conductivity (Lee's disc). The scanning electron microscopy was employed to found shape and size of iron(III) oxide particles adhesion quality of fiber with epoxy matrix. Good dispersion of fillers in matrix was achieved with surface modifier APTMS. Tensile, flexural, impact and inter laminar shear strength of composites was improved by reinforcing surface modified fiber and filler. Thermal stability of epoxy resin was improved when surface modified fiber was reinforced along with hard hematite particles. Thermal conductivity of epoxy increased with increase of hematite content in epoxy matrix.

  2. Dry powder inhaler formulation of lipid-polymer hybrid nanoparticles via electrostatically-driven nanoparticle assembly onto microscale carrier particles.

    PubMed

    Yang, Yue; Cheow, Wean Sin; Hadinoto, Kunn

    2012-09-15

    Lipid-polymer hybrid nanoparticles have emerged as promising nanoscale carriers of therapeutics as they combine the attractive characteristics of liposomes and polymers. Herein we develop dry powder inhaler (DPI) formulation of hybrid nanoparticles composed of poly(lactic-co-glycolic acid) and soybean lecithin as the polymer and lipid constituents, respectively. The hybrid nanoparticles are transformed into inhalable microscale nanocomposite structures by a novel technique based on electrostatically-driven adsorption of nanoparticles onto polysaccharide carrier particles, which eliminates the drawbacks of conventional techniques based on controlled drying (e.g. nanoparticle-specific formulation, low yield). First, we engineer polysaccharide carrier particles made up of chitosan cross-linked with tripolyphosphate and dextran sulphate to exhibit the desired aerosolization characteristics and physical robustness. Second, we investigate the effects of nanoparticle to carrier mass ratio and salt inclusion on the adsorption efficiency, in terms of the nanoparticle loading and yield, from which the optimal formulation is determined. Desorption of the nanoparticles from the carrier particles in phosphate buffer saline is also examined. Lastly, we characterize aerosolization efficiency of the nanocomposite product in vitro, where the emitted dose and respirable fraction are found to be comparable to the values of conventional DPI formulations.

  3. A discrete particle swarm optimization algorithm with local search for a production-based two-echelon single-vendor multiple-buyer supply chain

    NASA Astrophysics Data System (ADS)

    Seifbarghy, Mehdi; Kalani, Masoud Mirzaei; Hemmati, Mojtaba

    2016-11-01

    This paper formulates a two-echelon single-producer multi-buyer supply chain model, while a single product is produced and transported to the buyers by the producer. The producer and the buyers apply vendor-managed inventory mode of operation. It is assumed that the producer applies economic production quantity policy, which implies a constant production rate at the producer. The operational parameters of each buyer are sales quantity, sales price and production rate. Channel profit of the supply chain and contract price between the producer and each buyer is determined based on the values of the operational parameters. Since the model belongs to nonlinear integer programs, we use a discrete particle swarm optimization algorithm (DPSO) to solve the addressed problem; however, the performance of the DPSO is compared utilizing two well-known heuristics, namely genetic algorithm and simulated annealing. A number of examples are provided to verify the model and assess the performance of the proposed heuristics. Experimental results indicate that DPSO outperforms the rival heuristics, with respect to some comparison metrics.

  4. Variability of particle number emissions from diesel and hybrid diesel-electric buses in real driving conditions.

    PubMed

    Sonntag, Darrell B; Gao, H Oliver; Holmén, Britt A

    2008-08-01

    A linear mixed model was developed to quantify the variability of particle number emissions from transit buses tested in real-world driving conditions. Two conventional diesel buses and two hybrid diesel-electric buses were tested throughout 2004 under different aftertreatments, fuels, drivers, and bus routes. The mixed model controlled the confounding influence of factors inherent to on-board testing. Statistical tests showed that particle number emissions varied significantly according to the after treatment, bus route, driver, bus type, and daily temperature, with only minor variability attributable to differences between fuel types. The daily setup and operation of the sampling equipment (electrical low pressure impactor) and mini-dilution system contributed to 30-84% of the total random variability of particle measurements among tests with diesel oxidation catalysts. By controlling for the sampling day variability, the model better defined the differences in particle emissions among bus routes. In contrast, the low particle number emissions measured with diesel particle filters (decreased by over 99%) did not vary according to operating conditions or bus type but did vary substantially with ambient temperature.

  5. Identification of inelastic parameters based on deep drawing forming operations using a global-local hybrid Particle Swarm approach

    NASA Astrophysics Data System (ADS)

    Vaz, Miguel; Luersen, Marco A.; Muñoz-Rojas, Pablo A.; Trentin, Robson G.

    2016-04-01

    Application of optimization techniques to the identification of inelastic material parameters has substantially increased in recent years. The complex stress-strain paths and high nonlinearity, typical of this class of problems, require the development of robust and efficient techniques for inverse problems able to account for an irregular topography of the fitness surface. Within this framework, this work investigates the application of the gradient-based Sequential Quadratic Programming method, of the Nelder-Mead downhill simplex algorithm, of Particle Swarm Optimization (PSO), and of a global-local PSO-Nelder-Mead hybrid scheme to the identification of inelastic parameters based on a deep drawing operation. The hybrid technique has shown to be the best strategy by combining the good PSO performance to approach the global minimum basin of attraction with the efficiency demonstrated by the Nelder-Mead algorithm to obtain the minimum itself.

  6. Development of hybrid particle tracking algorithms and their applications in airflow measurement within an aircraft cabin mock-up

    NASA Astrophysics Data System (ADS)

    Yan, Wei

    Obtaining reliable experimental airflow data within an indoor environment is a challenging task and critical in studying and solving indoor air quality problems. The Hybrid Particle Tracking Velocimetry (HPTV) system is aimed at fulfilling this need. It was developed based on existing Particle Tracking Velocimety (PTV) and Volumetric Particle Tracking Velocimetry (VPTV) techniques. The HPTV system requires three charge-coupled device (CCD) cameras to view the illuminated flow field and capture the trajectories of the seeded particles. By adopting the hybrid spatial matching and object tracking algorithms, this system can acquire the 3-Dimensional velocity components within a large volume with relatively high spatial and temporal resolution. Synthetic images were employed to validate the performance of three components of the system: image processing, camera calibration and 3D velocity reconstruction. These three components are also the main error sources. The accuracy of the whole algorithm was analyzed and discussed through a back projection approach. The results showed that the algorithms performed effectively and accurately. The reconstructed 3D trajectories and streaks agreed well with the simulated streamline of the particles. As an overall testing and application of the system, HPTV was applied to measure the airflow pattern within a full-scale, five-row section of a Boeing 767-300 aircraft cabin mockup. A complete experimental procedure was developed and strictly followed throughout the experiment. Both global flow field at the whole cabin scale and the local flow field at the breathing zone of one passenger were studied. Each test case was also simulated numerically using a commercial computational fluid dynamic (CFD) package. Through comparison between the results from the numerical simulation and the experimental measurement, the potential model validation capability of the system was demonstrated. Possible reasons explaining the difference between

  7. Membrane flux dynamics in the submerged ultrafiltration hybrid treatment process during particle and natural organic matter removal.

    PubMed

    Zhang, Wei; Zhang, Xiaojian; Li, Yonghong; Wang, Jun; Chen, Chao

    2011-01-01

    Particles and natural organic matter (NOM) are two major concerns in surface water, which greatly influence the membrane filtration process. The objective of this article is to investigate the effect of particles, NOM and their interaction on the submerged ultrafiltration (UF) membrane flux under conditions of solo UF and coagulation and PAC adsorption as the pretreatment of UF. Particles, NOM and their mixture were spiked in tap water to simulate raw water. Exponential relationship, (J(P)/J(P0) = a x exp{-k[t-(n-1)T]}), was developed to quantify the normalized membrane flux dynamics during the filtration period and fitted the results well. In this equation, coefficient a was determined by the value of J(P)/J(P0) at the beginning of a filtration cycle, reflecting the flux recovery after backwashing, that is, the irreversible fouling. The coefficient k reflected the trend of flux dynamics. Integrated total permeability (SigmaJ(P)) in one filtration period could be used as a quantified indicator for comparison of different hybrid membrane processes or under different scenarios. According to the results, there was an additive effect on membrane flux by NOM and particles during solo UF process. This additive fouling could be alleviated by coagulation pretreatment since particles helped the formation of flocs with coagulant, which further delayed the decrease of membrane flux and benefited flux recovery by backwashing. The addition of PAC also increased membrane flux by adsorbing NOM and improved flux recovery through backwashing. PMID:22432326

  8. Lipoprotein(a) particle concentration and lipoprotein(a) cholesterol assays yield discordant classification of patients into four physiologically discrete groups.

    PubMed

    Konerman, Matthew; Kulkarni, Krishnaji; Toth, Peter P; Jones, Steven R

    2012-01-01

    There is little known about the relative predictive value of different lipoprotein(a) [Lp(a)] assays in clinical use, although each has been shown to predict similar incremental risk over conventional clinical and lipid risk factors. Thus, we examined the classification behavior of two commonly used Lp(a) assays and their associations with other lipid parameters. Serum lipid and Lp(a) concentrations were measured in 144 primary and secondary prevention patients. Lp(a) cholesterol [Lp(a)-C] was measured with the Vertical Auto Profile (upper limit of normal, 10 mg/dL). Lp(a) particle concentrations [Lp(a)-P] were measured with an isoform-independent molar assay (upper limit of normal, 70 nmol/L). The subjects were divided into the following four groups on the basis of their Lp(a)-C and Lp(a)-P levels: normal Lp(a)-P and Lp(a)-C; high Lp(a)-P and normal Lp(a)-C; normal Lp(a)-P and high Lp(a)-C; and high Lp(a)-P and Lp(a)-C. The proportion of subjects with values above the upper limit of normal was similar with both assays (P = .15). However, the Lp(a)-C and Lp(a)-P assays discordantly classified 23% of the study's subjects. In addition, the four Lp(a)-defined groups displayed differences in their relationships with other lipoproteins. The two groups with elevated Lp(a)-C showed significant associations with higher high-density lipoprotein cholesterol, apolipoprotein AI, and high-density lipoprotein cholesterol/apolipoprotein AI ratios. Triglycerides were also noted to be above normal in discordant and normal within concordant Lp(a) groups. Finally, the amount of cholesterol per Lp(a) particle [Lp(a)-C/Lp(a)-P] varied widely across the four groups. These findings suggest that the four Lp(a)-defined groups are physiologically discrete. Further investigation is warranted to assess which parameters among Lp(a)-P, Lp(a)-C, and Lp(a)-C/Lp(a)-P can be used to more accurately characterize Lp(a)-associated cardiovascular risk. PMID:22836074

  9. Multi-responsive hybrid particles: thermo-, pH-, photo-, and magneto-responsive magnetic hydrogel cores with gold nanorod optical triggers.

    PubMed

    Rittikulsittichai, Supparesk; Kolhatkar, Arati G; Sarangi, Subhasis; Vorontsova, Maria A; Vekilov, Peter G; Brazdeikis, Audrius; Randall Lee, T

    2016-06-01

    The research strategy described in this manuscript harnesses the attractive properties of hydrogels, gold nanorods (Aurods), and magnetic nanoparticles (MNPs) by synthesizing one unique multi-responsive nanostructure. This novel hybrid structure consists of silica-coated magnetic particles encapsulated within a thermo-responsive P(NIPAM-co-AA) hydrogel network on which Aurods are assembled. Furthermore, this research demonstrates that these composite particles respond to several forms of external stimuli (temperature, pH, light, and/or applied magnetic field) owing to their specific architecture. Exposure of the hybrid particles to external stimuli led to a systematic and reversible variation in the hydrodynamic diameter (swelling-deswelling) and thus in the optical properties of the hybrid particles (red-shifting of the plasmon band). Such stimuli-responsive volume changes can be effectively exploited in drug-delivery applications.

  10. Multi-responsive hybrid particles: thermo-, pH-, photo-, and magneto-responsive magnetic hydrogel cores with gold nanorod optical triggers

    NASA Astrophysics Data System (ADS)

    Rittikulsittichai, Supparesk; Kolhatkar, Arati G.; Sarangi, Subhasis; Vorontsova, Maria A.; Vekilov, Peter G.; Brazdeikis, Audrius; Randall Lee, T.

    2016-06-01

    The research strategy described in this manuscript harnesses the attractive properties of hydrogels, gold nanorods (Aurods), and magnetic nanoparticles (MNPs) by synthesizing one unique multi-responsive nanostructure. This novel hybrid structure consists of silica-coated magnetic particles encapsulated within a thermo-responsive P(NIPAM-co-AA) hydrogel network on which Aurods are assembled. Furthermore, this research demonstrates that these composite particles respond to several forms of external stimuli (temperature, pH, light, and/or applied magnetic field) owing to their specific architecture. Exposure of the hybrid particles to external stimuli led to a systematic and reversible variation in the hydrodynamic diameter (swelling-deswelling) and thus in the optical properties of the hybrid particles (red-shifting of the plasmon band). Such stimuli-responsive volume changes can be effectively exploited in drug-delivery applications.The research strategy described in this manuscript harnesses the attractive properties of hydrogels, gold nanorods (Aurods), and magnetic nanoparticles (MNPs) by synthesizing one unique multi-responsive nanostructure. This novel hybrid structure consists of silica-coated magnetic particles encapsulated within a thermo-responsive P(NIPAM-co-AA) hydrogel network on which Aurods are assembled. Furthermore, this research demonstrates that these composite particles respond to several forms of external stimuli (temperature, pH, light, and/or applied magnetic field) owing to their specific architecture. Exposure of the hybrid particles to external stimuli led to a systematic and reversible variation in the hydrodynamic diameter (swelling-deswelling) and thus in the optical properties of the hybrid particles (red-shifting of the plasmon band). Such stimuli-responsive volume changes can be effectively exploited in drug-delivery applications. Electronic supplementary information (ESI) available: Contains detailed information about the synthesis of

  11. Numerical simulation of Stokes flow around particles via a hybrid Finite Difference-Boundary Integral scheme

    NASA Astrophysics Data System (ADS)

    Bhattacharya, Amitabh

    2013-11-01

    An efficient algorithm for simulating Stokes flow around particles is presented here, in which a second order Finite Difference method (FDM) is coupled to a Boundary Integral method (BIM). This method utilizes the strong points of FDM (i.e. localized stencil) and BIM (i.e. accurate representation of particle surface). Specifically, in each iteration, the flow field away from the particles is solved on a Cartesian FDM grid, while the traction on the particle surface (given the the velocity of the particle) is solved using BIM. The two schemes are coupled by matching the solution in an intermediate region between the particle and surrounding fluid. We validate this method by solving for flow around an array of cylinders, and find good agreement with Hasimoto's (J. Fluid Mech. 1959) analytical results.

  12. Linear benchmarks between the hybrid codes HYMAGYC and HMGC to study energetic particle driven Alfvénic modes

    NASA Astrophysics Data System (ADS)

    Fogaccia, G.; Vlad, G.; Briguglio, S.

    2016-11-01

    Resonant interaction between energetic particles (EPs), produced by fusion reactions and/or additional heating systems, and shear Alfvén modes can destabilize global Alfvénic modes enhancing the EP transport. In order to investigate the EP transport in present and next generation fusion devices, numerical simulations are recognized as a very important tool. Among the various numerical models, the hybrid MHD gyrokinetic one has shown to be a valid compromise between a sufficiently accurate wave-particle interaction description and affordable computational resource requirements. This paper presents a linear benchmark between the hybrid codes HYMAGYC and HMGC. The HYMAGYC code solves the full, linear MHD equations in general curvilinear geometry for the bulk plasma and describes the EP population by the nonlinear gyrokinetic Vlasov equation. On the other side, HMGC solves the nonlinear, reduced O≤ft(ε 03\\right) , pressureless MHD equations ({ε0} being the inverse aspect ratio) for the bulk plasma and the drift kinetic Vlasov equation for the EPs. The results of the HYMAGYC and HMGC codes have been compared both in the MHD limit and in a wide range of the EP parameter space for two test cases (one of which being the so-called TAE n  =  6 ITPA Energetic Particle Group test case), both characterized by {ε0}\\ll 1 . In the first test case (test case A), good qualitative agreement is found w.r.t. real frequencies, growth rates and spatial structures of the most unstable modes, with some quantitative differences for the growth rates. For the so-called ITPA test case (test case B), at the nominal energetic particle density value, the disagreement between the two codes is, on the contrary, also qualitative, as a different mode is found as the most unstable one.

  13. Biomimetic synthesis of raspberry-like hybrid polymer-silica core-shell nanoparticles by templating colloidal particles with hairy polyamine shell.

    PubMed

    Pi, Mengwei; Yang, Tingting; Yuan, Jianjun; Fujii, Syuji; Kakigi, Yuichi; Nakamura, Yoshinobu; Cheng, Shiyuan

    2010-07-01

    The nanoparticles composed of polystyrene core and poly[2-(diethylamino)ethyl methacrylate] (PDEA) hairy shell were used as colloidal templates for in situ silica mineralization, allowing the well-controlled synthesis of hybrid silica core-shell nanoparticles with raspberry-like morphology and hollow silica nanoparticles by subsequent calcination. Silica deposition was performed by simply stirring a mixture of the polymeric core-shell particles in isopropanol, tetramethyl orthosilicate (TMOS) and water at 25 degrees C for 2.5h. No experimental evidence was found for nontemplated silica formation, which indicated that silica deposition occurred exclusively in the PDEA shell and formed PDEA-silica hybrid shell. The resulting hybrid silica core-shell particles were characterized by transmission electron microscopy (TEM), thermogravimetry, aqueous electrophoresis, and X-ray photoelectron spectroscopy. TEM studies indicated that the hybrid particles have well-defined core-shell structure with raspberry morphology after silica deposition. We found that the surface nanostructure of hybrid nanoparticles and the composition distribution of PDEA-silica hybrid shell could be well controlled by adjusting the silicification conditions. These new hybrid core-shell nanoparticles and hollow silica nanoparticles would have potential applications for high-performance coatings, encapsulation and delivery of active organic molecules.

  14. Biomimetic synthesis of raspberry-like hybrid polymer-silica core-shell nanoparticles by templating colloidal particles with hairy polyamine shell.

    PubMed

    Pi, Mengwei; Yang, Tingting; Yuan, Jianjun; Fujii, Syuji; Kakigi, Yuichi; Nakamura, Yoshinobu; Cheng, Shiyuan

    2010-07-01

    The nanoparticles composed of polystyrene core and poly[2-(diethylamino)ethyl methacrylate] (PDEA) hairy shell were used as colloidal templates for in situ silica mineralization, allowing the well-controlled synthesis of hybrid silica core-shell nanoparticles with raspberry-like morphology and hollow silica nanoparticles by subsequent calcination. Silica deposition was performed by simply stirring a mixture of the polymeric core-shell particles in isopropanol, tetramethyl orthosilicate (TMOS) and water at 25 degrees C for 2.5h. No experimental evidence was found for nontemplated silica formation, which indicated that silica deposition occurred exclusively in the PDEA shell and formed PDEA-silica hybrid shell. The resulting hybrid silica core-shell particles were characterized by transmission electron microscopy (TEM), thermogravimetry, aqueous electrophoresis, and X-ray photoelectron spectroscopy. TEM studies indicated that the hybrid particles have well-defined core-shell structure with raspberry morphology after silica deposition. We found that the surface nanostructure of hybrid nanoparticles and the composition distribution of PDEA-silica hybrid shell could be well controlled by adjusting the silicification conditions. These new hybrid core-shell nanoparticles and hollow silica nanoparticles would have potential applications for high-performance coatings, encapsulation and delivery of active organic molecules. PMID:20347275

  15. Modelling and real-time simulation of continuous-discrete systems in mechatronics

    SciTech Connect

    Lindow, H.

    1996-12-31

    This work presents a methodology for simulation and modelling of systems with continuous - discrete dynamics. It derives hybrid discrete event models from Lagrange`s equations of motion. This method combines continuous mechanical, electrical and thermodynamical submodels on one hand with discrete event models an the other hand into a hybrid discrete event model. This straight forward software development avoids numeric overhead.

  16. Magnetic particle-based sandwich sensor with DNA-modified carbon nanotubes as recognition elements for detection of DNA hybridization.

    PubMed

    Hu, Po; Huang, Cheng Zhi; Li, Yuan Fang; Ling, Jian; Liu, Yu Ling; Fei, Liang Run; Xie, Jian Ping

    2008-03-01

    In this contribution, we design a visual sensor for DNA hybridization with DNA probe-modified magnetic particles (MPs) and multiwalled carbon nanotubes (MWNTs) without involving a visual recognition element such as fluorescent/chemiluminescent reagents. It was found that DNA probe-modified MWNTs, which could be dispersed in aqueous medium and have strong light scattering signals under the excitation of a light beam in the UV-vis region, could connect with DNA probe-modified MPs together in the presence of perfectly complementary target DNA and form a sandwich structure. In a magnetic field, the formed MP-MWNT species can easily be removed from the solution, resulting in a decrease of light scattering signals. Thus, a magnetic particle-based sandwich sensor could be developed to detect DNA hybridization by measuring the light scattering signals with DNA-modified MWNTs as recognition elements. Experiments showed that the DNA-modified MPs sensor could be reused at least 17 times and was stable for more than 6 months.

  17. Interest rate next-day variation prediction based on hybrid feedforward neural network, particle swarm optimization, and multiresolution techniques

    NASA Astrophysics Data System (ADS)

    Lahmiri, Salim

    2016-02-01

    Multiresolution analysis techniques including continuous wavelet transform, empirical mode decomposition, and variational mode decomposition are tested in the context of interest rate next-day variation prediction. In particular, multiresolution analysis techniques are used to decompose interest rate actual variation and feedforward neural network for training and prediction. Particle swarm optimization technique is adopted to optimize its initial weights. For comparison purpose, autoregressive moving average model, random walk process and the naive model are used as main reference models. In order to show the feasibility of the presented hybrid models that combine multiresolution analysis techniques and feedforward neural network optimized by particle swarm optimization, we used a set of six illustrative interest rates; including Moody's seasoned Aaa corporate bond yield, Moody's seasoned Baa corporate bond yield, 3-Month, 6-Month and 1-Year treasury bills, and effective federal fund rate. The forecasting results show that all multiresolution-based prediction systems outperform the conventional reference models on the criteria of mean absolute error, mean absolute deviation, and root mean-squared error. Therefore, it is advantageous to adopt hybrid multiresolution techniques and soft computing models to forecast interest rate daily variations as they provide good forecasting performance.

  18. Production of hybrid lipid-based particles loaded with inorganic nanoparticles and active compounds for prolonged topical release.

    PubMed

    García-González, C A; Sampaio da Sousa, A R; Argemí, A; López Periago, A; Saurina, J; Duarte, C M M; Domingo, C

    2009-12-01

    The production of particulate hybrid carriers containing a glyceryl monostearate (Lumulse GMS-K), a waxy triglyceride (Cutina HR), silanized TiO(2) and caffeine were investigated with the aim of producing sunscreens with UV-radiation protection properties. Particles were obtained using the supercritical PGSS (Particles from Gas Saturated Solutions) technique. This method takes advantages of the lower melting temperatures of the lipids obtained from the dissolution of CO(2) in the bulk mixture. Experiments were performed at 13 MPa and 345 K, according to previous melting point measurements. Blends containing Lumulse GMS-K and Cutina HR lipids (50 wt%) were loaded with silanized TiO(2) and caffeine in percentile proportions of 6 and 4 wt%, respectively. The particles produced were characterized using several analytical techniques as follows: system crystallinity was checked by X-ray diffraction and differential scanning calorimetry, thermal stability by thermogravimetric analysis, and morphology by scanning and transmission electron microscopy. Further, the UV-shielding ability of TiO(2) after its dispersion in the lipidic matrix was assessed by solid UV-vis spectroscopy. Preliminary results indicated that caffeine-loaded solid lipid particles presented a two-step dissolution profile, with an initial burst of 60 wt% of the loaded active agent. Lipid blends loaded with TiO(2) and caffeine encompassed the UV-filter behavior of TiO(2) and the photoaging prevention properties of caffeine.

  19. Robust hybrid raspberry-like hollow particles with complex structures: a facile method of swelling polymerization towards composite spheres.

    PubMed

    Zhang, Xu; Yao, Xiaohui; Wang, Xiaomei; Feng, Lei; Qu, Jiayan; Liu, Pange

    2014-02-14

    A novel robust hybrid raspberry-like TiO2/PS hollow particles with complex double-shelled structures have been fabricated in large quantities by a facile swelling polymerization approach based on commercially available hollow polystyrene (PS) spheres. The crosslinked-PS protrusions are wedged firmly into the TiO2 shell, making the resultant particles both chemically and mechanically robust. By simply tuning the monomer concentration, the hierarchical morphology (the size and number of protrusion) of the surfaces can be well-controlled. Due to the dual-sized hierarchical morphology, the particulate coating possesses superhydrophobicity (water contact angle ≈ 161°). Moreover, the well-compartmentalized character is similar to that of typical Janus particles. The special particles with interfacial activity can stabilize water-in-toluene (w/o) emulsions well. Meanwhile, a TiO2 double-shelled hollow sphere with a complex structure is achieved by calcination or solvent treatment. All these unique features derived from a readily available method will endow the products with a broader range of applications.

  20. Electronic structure of individual hybrid colloid particles studied by near-edge X-ray absorption fine structure (NEXAFS) spectroscopy in the X-ray microscope.

    PubMed

    Henzler, Katja; Guttmann, Peter; Lu, Yan; Polzer, Frank; Schneider, Gerd; Ballauff, Matthias

    2013-02-13

    The electronic structure of individual hybrid particles was studied by nanoscale near-edge X-ray absorption spectromicroscopy. The colloidal particles consist of a solid polystyrene core and a cross-linked poly-N-(isopropylacrylamide) shell with embedded crystalline titanium dioxide (TiO(2)) nanoparticles (d = 6 ± 3 nm). The TiO(2) particles are generated in the carrier network by a sol-gel process at room temperature. The hybrid particles were imaged with photon energy steps of 0.1 eV in their hydrated environment with a cryo transmission X-ray microscope (TXM) at the Ti L(2,3)-edge. By analyzing the image stacks, the obtained near-edge X-ray absorption fine structure (NEXAFS) spectra of our individual hybrid particles show clearly that our synthesis generates TiO(2) in the anastase phase. Additionally, our spectromicroscopy method permits the determination of the density distribution of TiO(2) in single carrier particles. Therefore, NEXAFS spectroscopy combined with TXM presents a unique method to get in-depth insight into the electronic structure of hybrid materials. PMID:23360082

  1. Hybrid alphavirus-rhabdovirus propagating replicon particles are versatile and potent vaccine vectors.

    PubMed

    Rose, Nina F; Publicover, Jean; Chattopadhyay, Anasuya; Rose, John K

    2008-04-15

    Self-propagating, infectious, virus-like particles are generated in animal cell lines transfected with a Semliki Forest virus RNA replicon encoding a single viral structural protein, the vesicular stomatitis virus (VSV) glycoprotein. We show here that these infectious particles, which we call propagating replicons, are potent inducers of neutralizing antibody in animals yet are nonpathogenic. Mice vaccinated with a single dose of the particles generated high titers of VSV-neutralizing antibody and were protected from a subsequent lethal challenge with VSV. Induction of antibody required RNA replication. We also report that additional genes (including an HIV-1 envelope protein gene) expressed from the propagating replicons induced strong cellular immune responses to the corresponding proteins after a single inoculation. Our studies reveal the potential of these particles as simple and safe vaccine vectors inducing strong humoral and cellular immune responses.

  2. New Hybrid Organic/Inorganic Polysilsesquioxane-Silica Particles as Sunscreens.

    PubMed

    Tolbert, Stephanie H; McFadden, Peter D; Loy, Douglas A

    2016-02-10

    Effectiveness of organic sunscreens is limited by phototoxicity and degradation. Both of which can be significantly reduced by encapsulation in hollow particles or covalent incorporation into the solid structure of particles, but direct comparisons of the two methods have not been reported. In this study, physical encapsulation and covalent incorporation of sunscreens were compared with 1 mol % salicylate and curcumeroid sunscreens. 2-Ethylhexyl salicylate was physically encapsulated in hollow silica nanoparticles prepared by oil-in-water (O/W) microemulsion polymerizations (E-Sal). Some of these particles were coated with an additional shell or cap of silica to reduce leaking of sunscreen (cap-E-Sal). Covalent incorporation involved co-polymerizing tetraethoxysilane (TEOS) with 0.2 mol % of new salicylate and curcuminoid sunscreen monomers with triethoxsilyl groups. Particles were prepared with the salicylate attached to the silica matrix through single silsesquioxane groups (pendant; P-Sal) and two silsesquioxane groups (bridged; B-Sal). Particles based on a new curcuminoid-bridged monomer were also prepared (B-Curc). Sunscreen leaching, photodegradation, and sunscreen performance were determined for the E-Sal, cap-E-Sal, P-Sal, B-Sal, and B-Curc particles. Covalent attachment, particularly with bridged sunscreen monomers, reduced leaching and photodegradation over physical encapsulation, even with capping. PMID:26730573

  3. Hybrid capillary-inserted microfluidic device for sheathless particle focusing and separation in viscoelastic flow.

    PubMed

    Nam, Jeonghun; Tan, Justin Kok Soon; Khoo, Bee Luan; Namgung, Bumseok; Leo, Hwa Liang; Lim, Chwee Teck; Kim, Sangho

    2015-11-01

    A novel microfluidic device which consists of two stages for particle focusing and separation using a viscoelastic fluid has been developed. A circular capillary tube was used for three-dimensional particle pre-alignment before the separation process, which was inserted in a polydimethylsiloxane microchannel. Particles with diameters of 5 and 10 μm were focused at the centerline in the capillary tube, and the location of particles was initialized at the first bifurcation. Then, 5 and 10 μm particles were successfully separated in the expansion region based on size-dependent lateral migration, with ∼99% separation efficiency. The proposed device was further applied to separation of MCF-7 cells from leukocytes. Based on the cell size distribution, an approximate size cutoff for separation was determined to be 16 μm. At 200 μl/min, 94% of MCF-7 cells were separated with the purity of ∼97%. According to the trypan blue exclusion assay, high viability (∼90%) could be achieved for the separated MCF-7 cells. The use of a commercially available capillary tube enables the device to be highly versatile in dealing with particles in a wide size range by using capillary tubes with different inner diameters. PMID:26734115

  4. Emergent Ultra-Long-Range Interactions Between Active Particles in Hybrid Active-Inactive Systems

    NASA Astrophysics Data System (ADS)

    Steimel, Joshua; Aragones, Juan; Hu, Helen; Qureshi, Naser; Alexander-Katz, Alfredo

    Particle-particle interactions determine the state of a system. Control over the range and magnitude of such interactions has been an active area of research for decades due to the fundamental challenges it poses in science and technology. Effective interactions between active particles have gathered much attention as they can lead to out-of-equilibrium cooperative states such as flocking. Inspired by nature, where active living cells coexist with lifeless, immobile objects and structures, here we study the effective interactions that appear in systems composed of active and passive mixtures of colloids. Our system is a two dimensional colloidal monolayer composed primarily of passive (inactive) colloids and a very small fraction of active (sinning) ferromagnetic colloids. We find an emergent ultra-long-range attractive interaction between active particles induced by the activity of the spinning particles and mediated by the elasticity of the passive medium. Interestingly, the appearance of such interaction depends on the spinning protocol and has a minimum actuation time scale below which no attraction is observed. Overall, these results clearly show that in the presence of elastic components, active particles can interact across very long distances without any chemical modification of the environment. Such a mechanism might potentially be important for some biological systems and can be harnessed for newer developments in synthetic active soft materials.

  5. Physical Methods for the Preparation of Hybrid Nanocomposite Polymer Latex Particles

    NASA Astrophysics Data System (ADS)

    Teixeira, Roberto F. A.; Bon, Stefan A. F.

    In this chapter, we will highlight conceptual physical approaches towards the fabrication of nanocomposite polymer latexes in which each individual latex particle contains one or more "hard" nanoparticles, such as clays, silicates, titanates, or other metal(oxides). By "physical approaches" we mean that the "hard" nanoparticles are added as pre-existing entities, and are not synthesized in situ as part of the nanocomposite polymer latex fabrication process. We will narrow our discussion to focus on physical methods that rely on the assembly of nanoparticles onto the latex particles after the latex particles have been formed, or its reciprocal analogue, the adhesion of polymer onto an inorganic nanoparticle. First, will discuss the phenomenon of heterocoagulation and its various driving forces, such as electrostatic interactions, the hydrophobic effect, and secondary molecular interactions. We will then address methods that involve assembly of nanoparticles onto or around the more liquid precursors (i.e., swollen/growing latex particles or monomer droplets). We will focus on the phenomenon of Pickering stabilization. We will then discuss features of particle interaction with soft interfaces, and see how the adhesion of particles onto emulsion droplets can be applied in suspension, miniemulsion, and emulsion polymerization. Finally, we will very briefly mention some interesting methods that make use of interface-driven templating for making well-defined assembled clusters and supracolloidal structures.

  6. Influence of plasma parameters on the absorption coefficient of alpha particles to lower hybrid waves in tokamaks

    SciTech Connect

    Wang, J.; Zhang, X. Yu, L.; Zhao, X.

    2014-12-15

    In tokamaks, fusion generated α particles may absorb lower hybrid (LH) wave energy, thus reducing the LH current drive efficiency. The absorption coefficient γ{sub α} of LH waves due to α particles changing with some typical parameters is calculated in this paper. Results show that γ{sub α} increases with the parallel refraction index n{sub ‖}, while decreases with the frequency of LH waves ω over a wide range. Higher background plasma temperature and toroidal magnetic field will increase the absorption. The absorption coefficient γ{sub α} increases with n{sub e} when n{sub e} ≤ 8 × 10{sup 19} m{sup −3}, while decreases with n{sub e} when n{sub e} becomes larger, and there is a peak value of γ{sub α} when n{sub e} ≈ 8 × 10{sup 19} m{sup −1} for the ITER-like scenario. The influence of spectral broadening in parametric decay instabilities on the absorption coefficient is evaluated. The value of γ{sub α} with n{sub ‖} being 2.5 is almost two times larger than that with n{sub ‖} being 2.0 and is even lager in the case of 2.9, which will obviously increase the absorption of the LH power by alpha particles.

  7. Emergent ultra-long-range interactions between active particles in hybrid active-inactive systems

    NASA Astrophysics Data System (ADS)

    Steimel, Joshua P.; Aragones, Juan L.; Hu, Helen; Qureshi, Naser

    2016-04-01

    Particle-particle interactions determine the state of a system. Control over the range of such interactions as well as their magnitude has been an active area of research for decades due to the fundamental challenges it poses in science and technology. Very recently, effective interactions between active particles have gathered much attention as they can lead to out-of-equilibrium cooperative states such as flocking. Inspired by nature, where active living cells coexist with lifeless objects and structures, here we study the effective interactions that appear in systems composed of active and passive mixtures of colloids. Our systems are 2D colloidal monolayers composed primarily of passive (inactive) colloids, and a very small fraction of active (spinning) ferromagnetic colloids. We find an emergent ultra-long-range attractive interaction induced by the activity of the spinning particles and mediated by the elasticity of the passive medium. Interestingly, the appearance of such interaction depends on the spinning protocol and has a minimum actuation timescale below which no attraction is observed. Overall, these results clearly show that, in the presence of elastic components, active particles can interact across very long distances without any chemical modification of the environment. Such a mechanism might potentially be important for some biological systems and can be harnessed for newer developments in synthetic active soft materials.

  8. Emergent ultra-long-range interactions between active particles in hybrid active-inactive systems.

    PubMed

    Steimel, Joshua P; Aragones, Juan L; Hu, Helen; Qureshi, Naser; Alexander-Katz, Alfredo

    2016-04-26

    Particle-particle interactions determine the state of a system. Control over the range of such interactions as well as their magnitude has been an active area of research for decades due to the fundamental challenges it poses in science and technology. Very recently, effective interactions between active particles have gathered much attention as they can lead to out-of-equilibrium cooperative states such as flocking. Inspired by nature, where active living cells coexist with lifeless objects and structures, here we study the effective interactions that appear in systems composed of active and passive mixtures of colloids. Our systems are 2D colloidal monolayers composed primarily of passive (inactive) colloids, and a very small fraction of active (spinning) ferromagnetic colloids. We find an emergent ultra-long-range attractive interaction induced by the activity of the spinning particles and mediated by the elasticity of the passive medium. Interestingly, the appearance of such interaction depends on the spinning protocol and has a minimum actuation timescale below which no attraction is observed. Overall, these results clearly show that, in the presence of elastic components, active particles can interact across very long distances without any chemical modification of the environment. Such a mechanism might potentially be important for some biological systems and can be harnessed for newer developments in synthetic active soft materials.

  9. Discrete modelling of drapery systems

    NASA Astrophysics Data System (ADS)

    Thoeni, Klaus; Giacomini, Anna

    2016-04-01

    Drapery systems are an efficient and cost-effective measure in preventing and controlling rockfall hazards on rock slopes. The simplest form consists of a row of ground anchors along the top of the slope connected to a horizontal support cable from which a wire mesh is suspended down the face of the slope. Such systems are generally referred to as simple or unsecured draperies (Badger and Duffy 2012). Variations such as secured draperies, where a pattern of ground anchors is incorporated within the field of the mesh, and hybrid systems, where the upper part of an unsecured drapery is elevated to intercept rockfalls originating upslope of the installation, are becoming more and more popular. This work presents a discrete element framework for simulation of unsecured drapery systems and its variations. The numerical model is based on the classical discrete element method (DEM) and implemented into the open-source framework YADE (Šmilauer et al., 2010). The model takes all relevant interactions between block, drapery and slope into account (Thoeni et al., 2014) and was calibrated and validated based on full-scale experiments (Giacomini et al., 2012).The block is modelled as a rigid clump made of spherical particles which allows any shape to be approximated. The drapery is represented by a set of spherical particle with remote interactions. The behaviour of the remote interactions is governed by the constitutive behaviour of the wire and generally corresponds to a piecewise linear stress-strain relation (Thoeni et al., 2013). The same concept is used to model wire ropes. The rock slope is represented by rigid triangular elements where material properties (e.g., normal coefficient of restitution, friction angle) are assigned to each triangle. The capabilities of the developed model to simulate drapery systems and estimate the residual hazard involved with such systems is shown. References Badger, T.C., Duffy, J.D. (2012) Drapery systems. In: Turner, A.K., Schuster R

  10. Robustness measure of hybrid intra-particle entanglement, discord, and classical correlation with initial Werner state

    NASA Astrophysics Data System (ADS)

    Saha, P.; Sarkar, D.

    2016-02-01

    Quantum information processing is largely dependent on the robustness of non-classical correlations, such as entanglement and quantum discord. However, all the realistic quantum systems are thermodynamically open and lose their coherence with time through environmental interaction. The time evolution of quantum entanglement, discord, and the respective classical correlation for a single, spin-1/2 particle under spin and energy degrees of freedom, with an initial Werner state, has been investigated in the present study. The present intra-particle system is considered to be easier to produce than its inter-particle counterpart. Experimentally, this type of system may be realized in the well-known Penning trap. The most stable correlation was identified through maximization of a system-specific global objective function. Quantum discord was found to be the most stable, followed by the classical correlation. Moreover, all the correlations were observed to attain highest robustness under initial Bell state, with minimum possible dephasing and decoherence parameters.

  11. Measurement of Fine Particles From Mobile and Stationary Sources, and Reducing the Air Conditioner Power Consumption in Hybrid Electric Vehicles

    NASA Astrophysics Data System (ADS)

    Brewer, Eli Henry

    We study the PM2.5and ultrafine exhaust emissions from a new natural gas-fired turbine power facility to better understand air pollution in California. To characterize the emissions from new natural gas turbines, a series of tests were performed on a GE LMS100 gas turbine. These tests included PM2.5 and wet chemical tests for SO2/SO 3 and NH3, as well as ultrafine (less than 100 nm in diameter) particulate matter measurements. The turbine exhaust had an average particle number concentration that was 2.3x103 times higher than ambient air. The majority of these particles were nanoparticles; at the 100 nm size, stack particle concentrations were about 20 times higher than ambient, and increased to 3.9x104 times higher on average in the 2.5 - 3 nm particle size range. This study also found that ammonia emissions were higher than expected, but in compliance with permit conditions. This was possibly due to an ammonia imbalance entering the catalyst, some flue gas bypassing the catalyst, or not enough catalyst volume. SO3 accounted for an average of 23% of the total sulfur oxides emissions measured. Some of the SO3 is formed in the combustion process, it is likely that the majority formed as the SO2 in the combustion products passed across the oxidizing CO catalyst and SCR catalyst. The 100 MW turbine sampled in this study emitted particle loadings similar to those previously measured from turbines in the SCAQMD area, however, the turbine exhaust contained far more particles than ambient air. The power consumed by an air conditioner accounts for a significant fraction of the total power used by hybrid and electric vehicles especially during summer. This study examined the effect of recirculation of cabin air on power consumption of mobile air conditioners both in-lab and on-road. Real time power consumption and vehicle mileage were recorded by an On Board Diagnostic monitor and carbon balance method. Vehicle mileage improved with increased cabin air recirculation. The

  12. Discrete anti-gravity

    SciTech Connect

    Noyes, H.P. ); Starson, S. )

    1991-03-01

    Discrete physics, because it replaces time evolution generated by the energy operator with a global bit-string generator (program universe) and replaces fields'' with the relativistic Wheeler-Feynman action at a distance,'' allows the consistent formulation of the concept of signed gravitational charge for massive particles. The resulting prediction made by this version of the theory is that free anti-particles near the surface of the earth will fall'' up with the same acceleration that the corresponding particles fall down. So far as we can see, no current experimental information is in conflict with this prediction of our theory. The experiment crusis will be one of the anti-proton or anti-hydrogen experiments at CERN. Our prediction should be much easier to test than the small effects which those experiments are currently designed to detect or bound. 23 refs.

  13. Silicon PIN diode hybrid arrays for charged particle detection: Building blocks for vertex detectors at the SSC

    SciTech Connect

    Kramer, G.; Gaalema, S.; Shapiro, S.L.; Dunwoodie, W.M.; Arens, J.F.; Jernigan, J.G.

    1989-05-01

    Two-dimensional arrays of solid state detectors have long been used in visible and infrared systems. Hybrid arrays with separately optimized detector and readout substrates have been extensively developed for infrared sensors. The characteristics and use of these infrared readout chips with silicon PIN diode arrays produced by MICRON SEMICONDUCTOR for detecting high-energy particles are reported. Some of these arrays have been produced in formats as large as 512 /times/ 512 pixels; others have been radiation hardened to total dose levels beyond 1 Mrad. Data generation rates of 380 megasamples/second have been achieved. Analog and digital signal transmission and processing techniques have also been developed to accept and reduce these high data rates. 9 refs., 15 figs., 2 tabs.

  14. Hybrid PDMS/glass microfluidics for high resolution imaging and application to sub-wavelength particle trapping.

    PubMed

    Tonin, Mario; Descharmes, Nicolas; Houdré, Romuald

    2016-02-01

    We demonstrate the fabrication of a hybrid PDMS/glass microfluidic layer that can be placed on top of non-transparent samples and allows high-resolution optical microscopy through it. The layer mimics a glass coverslip to limit optical aberrations and can be applied on the sample without the use of permanent bonding. The bonding strength can withstand to hold up to 7 bars of injected pressure in the channel without leaking or breaking. We show that this process is compatible with multilayer soft lithography for the implementation of flexible valves. The benefits of this application is illustrated by optically trapping sub-wavelength particles and manipulate them around photonic nano-structures. Among others, we achieve close to diffraction limited imaging through the microfluidic assembly, full control on the flow with no dynamical deformations of the membrane and a 20-fold improvement on the stiffness of the trap at equivalent trapping power.

  15. Electromagnetic particle simulation of the effect of toroidicity on linear mode conversion and absorption of lower hybrid waves

    NASA Astrophysics Data System (ADS)

    Bao, J.; Lin, Z.; Kuley, A.; Wang, Z. X.

    2016-06-01

    Effects of toroidicity on linear mode conversion and absorption of lower hybrid (LH) waves in fusion plasmas have been studied using electromagnetic particle simulation. The simulation confirms that the toroidicity induces an upshift of parallel refractive index when LH waves propagate from the tokamak edge toward the core, which affects the radial position for the mode conversion between slow and fast LH waves. Furthermore, moving LH antenna launch position from low field side toward high field side leads to a larger upshift of the parallel refractive index, which helps the slow LH wave penetration into the tokamak core. The broadening of the poloidal spectrum of the wave-packet due to wave diffraction is also verified in the simulation. Both the upshift and broadening effects of the parallel spectrum of the wave-packet modify the parallel phase velocity and thus the linear absorption of LH waves by electron Landau resonance.

  16. Particle simulations of mode conversion between slow mode and fast mode in lower hybrid range of frequencies

    NASA Astrophysics Data System (ADS)

    Jia, Guozhang; Xiang, Nong; Wang, Xueyi; Huang, Yueheng; Lin, Yu

    2016-01-01

    The propagation and mode conversion of lower hybrid waves in an inhomogeneous plasma are investigated by using the nonlinear δf algorithm in a two-dimensional particle-in-cell simulation code based on the gyrokinetic electron and fully kinetic ion (GeFi) scheme [Lin et al., Plasma Phys. Controlled Fusion 47, 657 (2005)]. The characteristics of the simulated waves, such as wavelength, frequency, phase, and group velocities, agree well with the linear theoretical analysis. It is shown that a significant reflection component emerges in the conversion process between the slow mode and the fast mode when the scale length of the density variation is comparable to the local wavelength. The dependences of the reflection coefficient on the scale length of the density variation are compared with the results based on the linear full wave model for cold plasmas. It is indicated that the mode conversion for the waves with a frequency of 2.45 GHz (ω ˜ 3ωLH, where ωLH represents the lower hybrid resonance) and within Tokamak relevant amplitudes can be well described in the linear scheme. As the frequency decreases, the modification due to the nonlinear term becomes important. For the low-frequency waves (ω ˜ 1.3ωLH), the generations of the high harmonic modes and sidebands through nonlinear mode-mode coupling provide new power channels and thus could reduce the reflection significantly.

  17. Particle size distribution and morphological changes in activated carbon-metal oxide hybrid catalysts prepared under different heating conditions.

    PubMed

    Barroso-Bogeat, A; Alexandre-Franco, M; Fernández-González, C; Gómez-Serrano, V

    2016-03-01

    In catalysis processes, activated carbon (AC) and metal oxides (MOs) are widely used either as catalysts or as catalyst supports because of their unique properties. A combination of AC and a MO in a single hybrid material entails changes not only in the composition, microstructure and texture but also in the morphology, which may largely influence the catalytic behaviour of the resulting product. This work is aimed at investigating the modifications in the morphology and particle size distribution (PSD) for AC-MO hybrid catalysts as a result of their preparation under markedly different heating conditions. From a commercial AC and six MO (Al2O3, Fe2O3, ZnO, SnO2, TiO2 and WO3) precursors, two series of such catalysts are prepared by wet impregnation, oven-drying at 120 ºC, and subsequent heat treatment at 200 ºC or 850 ºC in inert atmosphere. The resulting samples are characterized in terms of their morphology and PSD by scanning electron microscopy and ImageJ processing program. Obtained results indicate that the morphology, PSD and degree of dispersion of the supported catalysts are strongly dependent both on the MO precursor and the heat treatment temperature. With the temperature rise, trends are towards the improvement of crystallinity, the broadening of the PSD and the increase in the average particle size, thus suggesting the involvement of sintering mechanisms. Such effects are more pronounced for the Fe, Sn and W catalysts due to the reduction of the corresponding MOs by AC during the heat treatment at 850 ºC.

  18. Emergent ultra–long-range interactions between active particles in hybrid active–inactive systems

    PubMed Central

    Steimel, Joshua P.; Aragones, Juan L.; Hu, Helen; Qureshi, Naser; Alexander-Katz, Alfredo

    2016-01-01

    Particle–particle interactions determine the state of a system. Control over the range of such interactions as well as their magnitude has been an active area of research for decades due to the fundamental challenges it poses in science and technology. Very recently, effective interactions between active particles have gathered much attention as they can lead to out-of-equilibrium cooperative states such as flocking. Inspired by nature, where active living cells coexist with lifeless objects and structures, here we study the effective interactions that appear in systems composed of active and passive mixtures of colloids. Our systems are 2D colloidal monolayers composed primarily of passive (inactive) colloids, and a very small fraction of active (spinning) ferromagnetic colloids. We find an emergent ultra–long-range attractive interaction induced by the activity of the spinning particles and mediated by the elasticity of the passive medium. Interestingly, the appearance of such interaction depends on the spinning protocol and has a minimum actuation timescale below which no attraction is observed. Overall, these results clearly show that, in the presence of elastic components, active particles can interact across very long distances without any chemical modification of the environment. Such a mechanism might potentially be important for some biological systems and can be harnessed for newer developments in synthetic active soft materials. PMID:27071096

  19. Determination of the ruminant origin of bone particles using fluorescence in situ hybridization (FISH)

    PubMed Central

    Lecrenier, M. C.; Ledoux, Q.; Berben, G.; Fumière, O.; Saegerman, C.; Baeten, V.; Veys, P.

    2014-01-01

    Molecular biology techniques such as PCR constitute powerful tools for the determination of the taxonomic origin of bones. DNA degradation and contamination by exogenous DNA, however, jeopardise bone identification. Despite the vast array of techniques used to decontaminate bone fragments, the isolation and determination of bone DNA content are still problematic. Within the framework of the eradication of transmissible spongiform encephalopathies (including BSE, commonly known as “mad cow disease”), a fluorescence in situ hybridization (FISH) protocol was developed. Results from the described study showed that this method can be applied directly to bones without a demineralisation step and that it allows the identification of bovine and ruminant bones even after severe processing. The results also showed that the method is independent of exogenous contamination and that it is therefore entirely appropriate for this application. PMID:25034259

  20. Determination of the ruminant origin of bone particles using fluorescence in situ hybridization (FISH).

    PubMed

    Lecrenier, M C; Ledoux, Q; Berben, G; Fumière, O; Saegerman, C; Baeten, V; Veys, P

    2014-01-01

    Molecular biology techniques such as PCR constitute powerful tools for the determination of the taxonomic origin of bones. DNA degradation and contamination by exogenous DNA, however, jeopardise bone identification. Despite the vast array of techniques used to decontaminate bone fragments, the isolation and determination of bone DNA content are still problematic. Within the framework of the eradication of transmissible spongiform encephalopathies (including BSE, commonly known as "mad cow disease"), a fluorescence in situ hybridization (FISH) protocol was developed. Results from the described study showed that this method can be applied directly to bones without a demineralisation step and that it allows the identification of bovine and ruminant bones even after severe processing. The results also showed that the method is independent of exogenous contamination and that it is therefore entirely appropriate for this application. PMID:25034259

  1. Determination of the ruminant origin of bone particles using fluorescence in situ hybridization (FISH).

    PubMed

    Lecrenier, M C; Ledoux, Q; Berben, G; Fumière, O; Saegerman, C; Baeten, V; Veys, P

    2014-07-17

    Molecular biology techniques such as PCR constitute powerful tools for the determination of the taxonomic origin of bones. DNA degradation and contamination by exogenous DNA, however, jeopardise bone identification. Despite the vast array of techniques used to decontaminate bone fragments, the isolation and determination of bone DNA content are still problematic. Within the framework of the eradication of transmissible spongiform encephalopathies (including BSE, commonly known as "mad cow disease"), a fluorescence in situ hybridization (FISH) protocol was developed. Results from the described study showed that this method can be applied directly to bones without a demineralisation step and that it allows the identification of bovine and ruminant bones even after severe processing. The results also showed that the method is independent of exogenous contamination and that it is therefore entirely appropriate for this application.

  2. Reduced discretization error in HZETRN

    NASA Astrophysics Data System (ADS)

    Slaba, Tony C.; Blattnig, Steve R.; Tweed, John

    2013-02-01

    The deterministic particle transport code HZETRN is an efficient analysis tool for studying the effects of space radiation on humans, electronics, and shielding materials. In a previous work, numerical methods in the code were reviewed, and new methods were developed that further improved efficiency and reduced overall discretization error. It was also shown that the remaining discretization error could be attributed to low energy light ions (A < 4) with residual ranges smaller than the physical step-size taken by the code. Accurately resolving the spectrum of low energy light particles is important in assessing risk associated with astronaut radiation exposure. In this work, modifications to the light particle transport formalism are presented that accurately resolve the spectrum of low energy light ion target fragments. The modified formalism is shown to significantly reduce overall discretization error and allows a physical approximation to be removed. For typical step-sizes and energy grids used in HZETRN, discretization errors for the revised light particle transport algorithms are shown to be less than 4% for aluminum and water shielding thicknesses as large as 100 g/cm2 exposed to both solar particle event and galactic cosmic ray environments.

  3. Reduced discretization error in HZETRN

    SciTech Connect

    Slaba, Tony C.; Blattnig, Steve R.; Tweed, John

    2013-02-01

    The deterministic particle transport code HZETRN is an efficient analysis tool for studying the effects of space radiation on humans, electronics, and shielding materials. In a previous work, numerical methods in the code were reviewed, and new methods were developed that further improved efficiency and reduced overall discretization error. It was also shown that the remaining discretization error could be attributed to low energy light ions (A < 4) with residual ranges smaller than the physical step-size taken by the code. Accurately resolving the spectrum of low energy light particles is important in assessing risk associated with astronaut radiation exposure. In this work, modifications to the light particle transport formalism are presented that accurately resolve the spectrum of low energy light ion target fragments. The modified formalism is shown to significantly reduce overall discretization error and allows a physical approximation to be removed. For typical step-sizes and energy grids used in HZETRN, discretization errors for the revised light particle transport algorithms are shown to be less than 4% for aluminum and water shielding thicknesses as large as 100 g/cm{sup 2} exposed to both solar particle event and galactic cosmic ray environments.

  4. Orientation control of liquid crystals using carbon-nanotube-magnetic particle hybrid materials.

    PubMed

    Jeong, Hyeon Su; Youn, Sang Cheon; Kim, Yun Ho; Jung, Hee-Tae

    2013-06-28

    We have developed a simple yet versatile method for aligning liquid crystals (LCs) by using magnetic-field oriented single-walled carbon nanotubes (SWNTs) that were modified with magnetic particles. A high degree of homeotropic/planar LC alignment was achieved by SWNTs being exposed to a very low strength magnetic field, combined with strong π-π interactions between the biphenyl group in the LCs and the wall of the SWNTs. PMID:23676827

  5. Unsteady Analysis of Particle Transport and Deposition in the Human Lung: A Hybrid 3D/0D Model

    NASA Astrophysics Data System (ADS)

    Haworth, Daniel C.; Kunz, Robert F.; Leemhuis, Laura S.; Banks, Syreeta S.; Kriete, Andres

    2003-11-01

    Three-dimensional CFD meshes including up the sixteenth generation of branching in a human tracheo-bronchial tree have been generated from surface data extracted using novel high-resolution bio-medical imaging and rendering methods. A zero-dimensional model for the deeper generations has been coupled with the three-dimensional model at each of the truncated branches. The 0D model imposes a time-varying volume to simulate realistic breathing cycles; it also includes a simple model for particle deposition. The resulting hybrid 3D/0D model has been exercised to compute the transport and deposition rates of particles of different sizes through full breathing cycles. Results are compared to earlier steady-flow CFD results, to results obtained using one-dimensional functional models of the human lung, and to experimental and modeling results for idealized branching-duct configurations. The aim of the research is to develop a virtual human respiratory system that can be used to address issues in pulmonary health in

  6. Computational prediction of molecular hydration entropy with hybrid scaled particle theory and free-energy perturbation method.

    PubMed

    Choi, Hwanho; Kang, Hongsuk; Park, Hwangseo

    2015-10-13

    Despite the importance of the knowledge of molecular hydration entropy (ΔShyd) in chemical and biological processes, the exact calculation of ΔShyd is very difficult, because of the complexity in solute-water interactions. Although free-energy perturbation (FEP) methods have been employed quite widely in the literature, the poor convergent behavior of the van der Waals interaction term in the potential function limited the accuracy and robustness. In this study, we propose a new method for estimating ΔShyd by means of combining the FEP approach and the scaled particle theory (or information theory) to separately calculate the electrostatic solute-water interaction term (ΔSelec) and the hydrophobic contribution approximated by the cavity formation entropy (ΔScav), respectively. Decomposition of ΔShyd into ΔScav and ΔSelec terms is found to be very effective with a substantial accuracy enhancement in ΔShyd estimation, when compared to the conventional full FEP calculations. ΔScav appears to dominate over ΔSelec in magnitude, even in the case of polar solutes, implying that the major contribution to the entropic cost for hydration comes from the formation of a solvent-excluded volume. Our hybrid scaled particle theory and FEP method is thus found to enhance the accuracy of ΔShyd prediction by effectively complementing the conventional full FEP method.

  7. Electromagnetic particle simulation of the linear mode conversion and the nonlinear parametric decay instability of lower hybrid waves in tokamaks

    NASA Astrophysics Data System (ADS)

    Bao, Jian; Lin, Zhihong; Kuley, Animesh; Wang, Zhixuan

    2015-11-01

    An electromagnetic fluid-kinetic model is developed to study the lower hybrid (LH) waves in tokamaks with low numerical noise, in which electron density is pushed forward by the continuity equation, and the kinetic markers are introduced for closure. A generalized weight-based particle-in-cell scheme is also applied to the simulation for the local high resolution in phase space. This new model has been successfully implemented into the global gyro-kinetic toroidal code (GTC), and the electromagnetic particle simulations of the LH waves have been carried out with a realistic electron-to-ion mass ratio. The simulation shows that toroidal effects induce an upshift of the parallel reflective index when LH waves propagate from the tokamak edge toward the core, which modifies the radial position for the mode conversion between slow and fast LH waves. The broadening of the poloidal spectrum of the wave-packet due to the wave diffraction is also observed in the simulation of LH wave propagation, and both the toroidal upshift and broadening effects of the wave-packet spectrum modify the parallel phase velocity and thus the linear absorption of LH waves by electrons through Landau resonance. In the nonlinear simulation, the LH wave can drive a net current during the propagation when its phase velocity gets closed to the local electron thermal speed. Finally, the parametric decay instability is observed when we increase the power of LH waves, in which a LH sideband and a low frequency ion plasma waves are generated.

  8. Wave-Particle Interactions Associated with Nongyrotropic Distribution Functions: A Hybrid Simulation Study

    NASA Technical Reports Server (NTRS)

    Convery, P. D.; Schriver, D.; Ashour-Abdalla, M.; Richard, R. L.

    2002-01-01

    Nongyrotropic plasma distribution functions can be formed in regions of space where guiding center motion breaks down as a result of strongly curved and weak ambient magnetic fields. Such are the conditions near the current sheet in the Earth's middle and distant magnetotail, where observations of nongyrotropic ion distributions have been made. Here a systematic parameter study of nongyrotropic proton distributions using electromagnetic hybrid simulations is made. We model the observed nongyrotropic distributions by removing a number of arc length segments from a cold ring distribution and find significant differences with the results of simulations that initially have a gyrotropic ring distribution. Model nongyrotropic distributions with initially small perpendicular thermalization produce growing fluctuations that diffuse the ions into a stable Maxwellian-like distribution within a few proton gyro periods. The growing waves produced by nongyrotropic distributions are similar to the electromagnetic proton cyclotron waves produced by a gyrotropic proton ring distribution in that they propagate parallel to the background magnetic field and occur at frequencies on the order of the proton gyrofrequency, The maximum energy of the fluctuating magnetic field increases as the initial proton distribution is made more nongyrotropic, that is, more highly bunched in perpendicular velocity space. This increase can be as much as twice the energy produced in the gyrotropic case.

  9. Damage Detection in Flexible Plates through Reduced-Order Modeling and Hybrid Particle-Kalman Filtering.

    PubMed

    Capellari, Giovanni; Azam, Saeed Eftekhar; Mariani, Stefano

    2015-12-22

    Health monitoring of lightweight structures, like thin flexible plates, is of interest in several engineering fields. In this paper, a recursive Bayesian procedure is proposed to monitor the health of such structures through data collected by a network of optimally placed inertial sensors. As a main drawback of standard monitoring procedures is linked to the computational costs, two remedies are jointly considered: first, an order-reduction of the numerical model used to track the structural dynamics, enforced with proper orthogonal decomposition; and, second, an improved particle filter, which features an extended Kalman updating of each evolving particle before the resampling stage. The former remedy can reduce the number of effective degrees-of-freedom of the structural model to a few only (depending on the excitation), whereas the latter one allows to track the evolution of damage and to locate it thanks to an intricate formulation. To assess the effectiveness of the proposed procedure, the case of a plate subject to bending is investigated; it is shown that, when the procedure is appropriately fed by measurements, damage is efficiently and accurately estimated.

  10. Damage Detection in Flexible Plates through Reduced-Order Modeling and Hybrid Particle-Kalman Filtering

    PubMed Central

    Capellari, Giovanni; Eftekhar Azam, Saeed; Mariani, Stefano

    2015-01-01

    Health monitoring of lightweight structures, like thin flexible plates, is of interest in several engineering fields. In this paper, a recursive Bayesian procedure is proposed to monitor the health of such structures through data collected by a network of optimally placed inertial sensors. As a main drawback of standard monitoring procedures is linked to the computational costs, two remedies are jointly considered: first, an order-reduction of the numerical model used to track the structural dynamics, enforced with proper orthogonal decomposition; and, second, an improved particle filter, which features an extended Kalman updating of each evolving particle before the resampling stage. The former remedy can reduce the number of effective degrees-of-freedom of the structural model to a few only (depending on the excitation), whereas the latter one allows to track the evolution of damage and to locate it thanks to an intricate formulation. To assess the effectiveness of the proposed procedure, the case of a plate subject to bending is investigated; it is shown that, when the procedure is appropriately fed by measurements, damage is efficiently and accurately estimated. PMID:26703615

  11. Synthesis of organic-inorganic hybrid sols with nano silica particles and organoalkoxysilanes for transparent and high-thermal-resistance coating films using sol-gel reaction.

    PubMed

    Na, Moonkyong; Park, Hoyyul; Ahn, Myeongsang; Lee, Hyeonhwa; Chung, Ildoo

    2010-10-01

    Organic-inorganic hybrid sols were synthesized from nano silica particles dispersed in water and from organoalkoxysilanes, using the sol-gel reaction. This work focuses on the effects of the three multifunctional organoalkoxysilanes dimethyldimethoxysilane (DMDMS), methyltrimethoxysilane (MTMS), and tetramethoxysilane (TMOS) to form a transparent and high-thermal-resistance coating film. The stability of the hybrid sol was evaluated as a function of the reaction time for 10 d through the variation of the viscosity. The viscosity of the silica/DMDMS and silica/MTMS sol was slightly increased for 10 d. The multifunctional organoalkoxysilanes formed dense silica networks through hydrolysis and condensation reaction, which enhanced the thermal resistance of the coating films. No thermal degradation of the silica/DMDMS sample occurred up to 600 degrees C, and none of the silica/MTMS and silica/TMOS samples occurred either up to 700 degrees C. The organic-inorganic hybrid sols were coated on the glass substrate using a spin-coating procedure. The organic-inorganic hybrid sols formed flat coating films without cracks. The transmittance of the hybrid sol coating films using MTMS and DMDMS was shown to be over 90%. The transmittance of the silica/TMOS sol coating film reacted for 10 d abruptly decreased due to faster gelation. The silica/DMDMS and silica/MTMS hybrid sols formed smooth coating films while the surface roughness of the silica/TMOS coating film markedly increased when the hybrid sol reacted for 10 d. The increase of the surface roughness of the silica/TMOS coating film can be attributed to the degradation of the stability of the hybrid sol and to the loss of transmittance of the coating film. It was confirmed in this study that the use of organic-inorganic hybrid sol can yield transparent and high-thermal-resistance coating films.

  12. Hybrid particle traps and conditioning procedure for gas insulated transmission lines

    DOEpatents

    Dale, Steinar J.; Cookson, Alan H.

    1982-01-01

    A gas insulated transmission line includes an outer sheath, an inner condor within the outer sheath, insulating supports supporting the inner conductor within the outer sheath, and an insulating gas electrically insulating the inner conductor from the outer sheath. An apertured particle trapping ring is disposed within the outer sheath, and the trapping ring has a pair of dielectric members secured at each longitudinal end thereof, with the dielectric members extending outwardly from the trapping ring along an arc. A support sheet having an adhesive coating thereon is secured to the trapping ring and disposed on the outer sheath within the low field region formed between the trapping ring and the outer sheath. A conditioning method used to condition the transmission line prior to activation in service comprises applying an AC voltage to the inner conductor in a plurality of voltage-time steps, with the voltage-time steps increasing in voltage magnitude while decreasing in time duration.

  13. Hybrid Models: Bridging Particle and Continuum Scales in Hydrodynamic Flow Simulations

    NASA Astrophysics Data System (ADS)

    Flekkoy, Eirik G.; McNamara, Sean; Maloy, Jorgen; Maloy, Knut; Feder, Jens; Wagner, Geri

    Different models for the coupling of field and particle descriptions are introduced and examined. For the purpose of establishing how a molecular description may be coupled to a continuum description of the same physical system, we study a molecular dynamics system coupled to a Navier-Stokes description within the same physical space. A simple toy model version of this system is studied as well, i.e., a system of random walkers coupled to the diffusion equation. These coupling schemes are shown to work in the sense that they provide a seamless coupling between the different representations. In order to establish a sufficiently computationally efficient method for the simulation of gas-grain flow, we introduce a model where the grains are described explicitly but where the gas is described only through its continuum pressure field. It is shown that this model easily produces macroscopic structures, such as the bubbles in fluidized beds. The model is also used to study a novel bubble instability observed experimentally in the flow of gas-grain systems in simple tubes.

  14. Hybrid micro-particles as a magnetically-guidable decontaminant for cesium-eluted ash slurry

    PubMed Central

    Namiki, Yoshihisa; Ueyama, Toshihiko; Yoshida, Takayuki; Watanabe, Ryoei; Koido, Shigeo; Namiki, Tamami

    2014-01-01

    Decontamination of the radioactive cesium that is widely dispersed owing to a nuclear power station accident and concentrated in fly ash requires an effective elimination system. Radioactive fly ash contains large amounts of water-soluble cesium that can cause severe secondary contamination and represents a serious health risk, yet its complete removal is complicated and difficult. Here it is shown that a new fine-powder formulation can be magnetically guided to eliminate cesium after being mixed with the ash slurry. This formulation, termed MagCE, consists of a ferromagnetic porous structure and alkaline- and salt-resistant nickel ferrocyanide. It has potent cesium-adsorption- and magnetic-separation-properties. Because of its resistance against physical and chemical attack such as with ash particles, as well as with the high pH and salt concentration of the ash slurry, MagCE simplifies the decontamination process without the need of the continued presence of the hazardous water-soluble cesium in the treated ash. PMID:25192495

  15. Simulation of Alfvén eigenmode bursts using a hybrid code for nonlinear magnetohydrodynamics and energetic particles

    NASA Astrophysics Data System (ADS)

    Todo, Y.; Berk, H. L.; Breizman, B. N.

    2012-03-01

    A hybrid simulation code for nonlinear magnetohydrodynamics (MHD) and energetic-particle dynamics has been extended to simulate recurrent bursts of Alfvén eigenmodes by implementing the energetic-particle source, collisions and losses. The Alfvén eigenmode bursts with synchronization of multiple modes and beam ion losses at each burst are successfully simulated with nonlinear MHD effects for the physics condition similar to a reduced simulation for a TFTR experiment (Wong et al 1991 Phys. Rev. Lett. 66 1874, Todo et al 2003 Phys. Plasmas 10 2888). It is demonstrated with a comparison between nonlinear MHD and linear MHD simulation results that the nonlinear MHD effects significantly reduce both the saturation amplitude of the Alfvén eigenmodes and the beam ion losses. Two types of time evolution are found depending on the MHD dissipation coefficients, namely viscosity, resistivity and diffusivity. The Alfvén eigenmode bursts take place for higher dissipation coefficients with roughly 10% drop in stored beam energy and the maximum amplitude of the dominant magnetic fluctuation harmonic δBm/n/B ~ 5 × 10-3 at the mode peak location inside the plasma. Quadratic dependence of beam ion loss rate on magnetic fluctuation amplitude is found for the bursting evolution in the nonlinear MHD simulation. For lower dissipation coefficients, the amplitude of the Alfvén eigenmodes is at steady levels δBm/n/B ~ 2 × 10-3 and the beam ion losses take place continuously. The beam ion pressure profiles are similar among the different dissipation coefficients, and the stored beam energy is higher for higher dissipation coefficients.

  16. Development of a fluorescence in situ hybridization protocol for the identification of micro-organisms associated with wastewater particles and flocs.

    PubMed

    Ormeci, Banu; Linden, Karl G

    2008-11-01

    Fluorescence in situ hybridization (FISH) provides a unique tool to study micro-organisms associated with particles and flocs. FISH enables visual examination of micro-organisms while they are structurally intact and associated with particles. However, application of FISH to wastewater and sludge samples presents a specific set of problems. Wastewater samples generate high background fluorescence due to their organic and inorganic content making it difficult to differentiate a probe-conferred signal from naturally fluorescing particles with reasonable certainty. Furthermore, some of the FISH steps involve harsh treatment of samples, and are likely to disrupt the floc structure. This study developed a FISH protocol for studying micro-organisms that are associated with particles and flocs. The results indicate that choice of a proper fluorochrome and labeling technique is a key step in reducing the background fluorescence and non-specific binding, and increasing the intensity of the probe signal. Compared to other fluorochromes tested, CY3 worked very well and enabled the observation of particles and debris in red and probe signal from microbes in yellow. Fixation, hybridization, and washing steps disturbed the floc structure and particle-microbe association. Modifications to these steps were necessary, and were achieved by replacing centrifugation with filtration and employment of nylon filters. Microscope slides generated excellent quality images, but polycarbonate membrane filters performed better in preserving the floc structure.

  17. Receptor-mediated membrane adhesion of lipid-polymer hybrid (LPH) nanoparticles studied by dissipative particle dynamics simulations

    PubMed Central

    2016-01-01

    Lipid–polymer hybrid (LPH) nanoparticles represent a novel class of targeted drug delivery platforms that combine the advantages of liposomes and biodegradable polymeric nanoparticles. However, the molecular details of the interaction between LPHs and their target cell membranes remain poorly understood. We have investigated the receptor-mediated membrane adhesion process of a ligand-tethered LPH nanoparticle using extensive dissipative particle dynamics (DPD) simulations. We found that the spontaneous adhesion process follows a first-order kinetics characterized by two distinct stages: a rapid nanoparticle–membrane engagement, followed by a slow growth in the number of ligand–receptor pairs coupled with structural re-organization of both the nanoparticle and the membrane. The number of ligand–receptor pairs increases with the dynamic segregation of ligands and receptors toward the adhesion zone causing an out-of-plane deformation of the membrane. Moreover, the fluidity of the lipid shell allows for strong nanoparticle–membrane interactions to occur even when the ligand density is low. The LPH–membrane avidity is enhanced by the increased stability of each receptor–ligand pair due to the geometric confinement and the cooperative effect arising from multiple binding events. Thus, our results reveal the unique advantages of LPH nanoparticles as active cell-targeting nanocarriers and provide some general principles governing nanoparticle–cell interactions that may aid future design of LPHs with improved affinity and specificity for a given target of interest. PMID:25438167

  18. Biodistribution study of nanometric hybrid gadolinium oxide particles as a multimodal SPECT/MR/optical imaging and theragnostic agent.

    PubMed

    Kryza, David; Taleb, Jacqueline; Janier, Marc; Marmuse, Laurence; Miladi, Imen; Bonazza, Pauline; Louis, Cédric; Perriat, Pascal; Roux, Stéphane; Tillement, Olivier; Billotey, Claire

    2011-06-15

    Nanometric hybrid gadolinium oxide particles (Gado-6Si-NP) for diagnostic and therapeutic applications (mean diameter 3-4 nm) were obtained by encapsulating Gd(2)O(3) cores within a polysiloxane shell, which carries organic fluorophore (Cy 5) and is derivatized by a hydrophilic carboxylic layer. As residency time in the living body and methods of waste elimination are crucial to defining a good nanoparticle candidate and moving forward with steps for validation, this study was aimed at evaluating the biodistribution of these multimodal Gado-6Si-NP in rodents. Gado-6Si-NP were imaged following intravenous injection in control Wistar rats and mice using MRI (7 T), optical fluorescent imaging, and SPECT. A clear correlation was observed among MRI, optical imaging, and SPECT regarding the renal elimination. Quantitative biodistribution using gamma-counting of each sampled organ confirmed that these nanoparticles circulated freely in the blood pool and were rapidly cleared by renal excretion without accumulation in liver and RES uptake. These results demonstrate that Gado-6Si-NP display optimal biodistribution properties, enabling them to be developed as multimodal agents for in vivo imaging and theragnostics, especially in oncological applications.

  19. Crude oil price forecasting based on hybridizing wavelet multiple linear regression model, particle swarm optimization techniques, and principal component analysis.

    PubMed

    Shabri, Ani; Samsudin, Ruhaidah

    2014-01-01

    Crude oil prices do play significant role in the global economy and are a key input into option pricing formulas, portfolio allocation, and risk measurement. In this paper, a hybrid model integrating wavelet and multiple linear regressions (MLR) is proposed for crude oil price forecasting. In this model, Mallat wavelet transform is first selected to decompose an original time series into several subseries with different scale. Then, the principal component analysis (PCA) is used in processing subseries data in MLR for crude oil price forecasting. The particle swarm optimization (PSO) is used to adopt the optimal parameters of the MLR model. To assess the effectiveness of this model, daily crude oil market, West Texas Intermediate (WTI), has been used as the case study. Time series prediction capability performance of the WMLR model is compared with the MLR, ARIMA, and GARCH models using various statistics measures. The experimental results show that the proposed model outperforms the individual models in forecasting of the crude oil prices series.

  20. Receptor-mediated membrane adhesion of lipid-polymer hybrid (LPH) nanoparticles studied by dissipative particle dynamics simulations

    NASA Astrophysics Data System (ADS)

    Li, Zhenlong; Gorfe, Alemayehu A.

    2014-12-01

    Lipid-polymer hybrid (LPH) nanoparticles represent a novel class of targeted drug delivery platforms that combine the advantages of liposomes and biodegradable polymeric nanoparticles. However, the molecular details of the interaction between LPHs and their target cell membranes remain poorly understood. We have investigated the receptor-mediated membrane adhesion process of a ligand-tethered LPH nanoparticle using extensive dissipative particle dynamics (DPD) simulations. We found that the spontaneous adhesion process follows a first-order kinetics characterized by two distinct stages: a rapid nanoparticle-membrane engagement, followed by a slow growth in the number of ligand-receptor pairs coupled with structural re-organization of both the nanoparticle and the membrane. The number of ligand-receptor pairs increases with the dynamic segregation of ligands and receptors toward the adhesion zone causing an out-of-plane deformation of the membrane. Moreover, the fluidity of the lipid shell allows for strong nanoparticle-membrane interactions to occur even when the ligand density is low. The LPH-membrane avidity is enhanced by the increased stability of each receptor-ligand pair due to the geometric confinement and the cooperative effect arising from multiple binding events. Thus, our results reveal the unique advantages of LPH nanoparticles as active cell-targeting nanocarriers and provide some general principles governing nanoparticle-cell interactions that may aid future design of LPHs with improved affinity and specificity for a given target of interest.

  1. Crude oil price forecasting based on hybridizing wavelet multiple linear regression model, particle swarm optimization techniques, and principal component analysis.

    PubMed

    Shabri, Ani; Samsudin, Ruhaidah

    2014-01-01

    Crude oil prices do play significant role in the global economy and are a key input into option pricing formulas, portfolio allocation, and risk measurement. In this paper, a hybrid model integrating wavelet and multiple linear regressions (MLR) is proposed for crude oil price forecasting. In this model, Mallat wavelet transform is first selected to decompose an original time series into several subseries with different scale. Then, the principal component analysis (PCA) is used in processing subseries data in MLR for crude oil price forecasting. The particle swarm optimization (PSO) is used to adopt the optimal parameters of the MLR model. To assess the effectiveness of this model, daily crude oil market, West Texas Intermediate (WTI), has been used as the case study. Time series prediction capability performance of the WMLR model is compared with the MLR, ARIMA, and GARCH models using various statistics measures. The experimental results show that the proposed model outperforms the individual models in forecasting of the crude oil prices series. PMID:24895666

  2. Receptor-mediated membrane adhesion of lipid-polymer hybrid (LPH) nanoparticles studied by dissipative particle dynamics simulations.

    PubMed

    Li, Zhenlong; Gorfe, Alemayehu A

    2015-01-14

    Lipid-polymer hybrid (LPH) nanoparticles represent a novel class of targeted drug delivery platforms that combine the advantages of liposomes and biodegradable polymeric nanoparticles. However, the molecular details of the interaction between LPHs and their target cell membranes remain poorly understood. We have investigated the receptor-mediated membrane adhesion process of a ligand-tethered LPH nanoparticle using extensive dissipative particle dynamics (DPD) simulations. We found that the spontaneous adhesion process follows a first-order kinetics characterized by two distinct stages: a rapid nanoparticle-membrane engagement, followed by a slow growth in the number of ligand-receptor pairs coupled with structural re-organization of both the nanoparticle and the membrane. The number of ligand-receptor pairs increases with the dynamic segregation of ligands and receptors toward the adhesion zone causing an out-of-plane deformation of the membrane. Moreover, the fluidity of the lipid shell allows for strong nanoparticle-membrane interactions to occur even when the ligand density is low. The LPH-membrane avidity is enhanced by the increased stability of each receptor-ligand pair due to the geometric confinement and the cooperative effect arising from multiple binding events. Thus, our results reveal the unique advantages of LPH nanoparticles as active cell-targeting nanocarriers and provide some general principles governing nanoparticle-cell interactions that may aid future design of LPHs with improved affinity and specificity for a given target of interest.

  3. Hybrid approach combining dissipative particle dynamics and finite-difference diffusion model: simulation of reactive polymer coupling and interfacial polymerization.

    PubMed

    Berezkin, Anatoly V; Kudryavtsev, Yaroslav V

    2013-10-21

    A novel hybrid approach combining dissipative particle dynamics (DPD) and finite difference (FD) solution of partial differential equations is proposed to simulate complex reaction-diffusion phenomena in heterogeneous systems. DPD is used for the detailed molecular modeling of mass transfer, chemical reactions, and phase separation near the liquid∕liquid interface, while FD approach is applied to describe the large-scale diffusion of reactants outside the reaction zone. A smooth, self-consistent procedure of matching the solute concentration is performed in the buffer region between the DPD and FD domains. The new model is tested on a simple model system admitting an analytical solution for the diffusion controlled regime and then applied to simulate practically important heterogeneous processes of (i) reactive coupling between immiscible end-functionalized polymers and (ii) interfacial polymerization of two monomers dissolved in immiscible solvents. The results obtained due to extending the space and time scales accessible to modeling provide new insights into the kinetics and mechanism of those processes and demonstrate high robustness and accuracy of the novel technique.

  4. A simple analysis of extinction spectra of cancerous and normal prostate tissues in near infrared range using a size discrete particle distribution and Mie scattering model

    NASA Astrophysics Data System (ADS)

    Zhou, Kenneth J.; Chen, Jun

    2015-03-01

    The extinction spectra and optical coefficients of human cancerous and normal prostate tissues were investigated in the spectral range of 750 nm - 860 nm. The scattering coefficient (μs) was determined from the extinction measurements on thin prostate tissue and Beer's law. The absorption coefficient (μa) and the reduced scattering coefficient (μs') were extracted from integrate sphere intensity measurements on prostate tissue of which the thickness is in the multiple scattering range. The anisotropy factor (g) was calculated using the extracted values of μs and μs'. A micro-optical model of soft biological tissue was introduced to simulate the numerical computation of the absolute magnitudes of its scattering coefficients from the refractive index and a particle distribution function based on the Mie theory. A key assumption of the model is that the refractive index variations caused by microscopic tissue elements can be treated as particles with sizes distributed according to a skewed log-normal distribution function. The particle distribution and mean particle size of the two types of tissues were then calculated. Results show that the mean diameter of the particle size of cancerous tissue is larger than that of the cancerous tissue, which is responsible for larger reduced scattering coefficient of normal tissue in comparison with cancerous tissue. The results can be explained the change of tissue during prostate cancer evolution defined by Gleason Grade. The difference of the particles distribution and optical coefficients of cancerous and normal prostate tissues may present a potential criterion for prostate cancer detection.

  5. Behavior of quasi-particles on hybrid spaces. Relations to the geometry of geodesics and to the problems of analytic number theory

    NASA Astrophysics Data System (ADS)

    Chernyshev, Vsevolod L.; Tolchennikov, Anton A.; Shafarevich, Andrei I.

    2016-09-01

    We review our recent results concerning the propagation of "quasi-particles" in hybrid spaces — topological spaces obtained from graphs via replacing their vertices by Riemannian manifolds. Although the problem is purely classical, it is initiated by the quantum one, namely, by the Cauchy problem for the time-dependent Schrödinger equation with localized initial data.We describe connections between the behavior of quasi-particles with the properties of the corresponding geodesic flows. We also describe connections of our problem with various problems in analytic number theory.

  6. A hybrid method for hydrodynamic-kinetic flow Part I: A particle-grid method for reducing stochastic noise in kinetic regimes

    SciTech Connect

    Alaia, Alessandro; Puppo, Gabriella

    2011-06-20

    In this work we present a hybrid particle-grid Monte Carlo method for the Boltzmann equation, which is characterized by a significant reduction of the stochastic noise in the kinetic regime. The hybrid method is based on a first order splitting in time to separate the transport from the relaxation step. The transport step is solved by a deterministic scheme, while a hybrid DSMC-based method is used to solve the collision step. Such a hybrid scheme is based on splitting the solution in a collisional and a non-collisional part at the beginning of the collision step, and the DSMC method is used to solve the relaxation step for the collisional part of the solution only. This is accomplished by sampling only the fraction of particles candidate for collisions from the collisional part of the solution, performing collisions as in a standard DSMC method, and then projecting the particles back onto a velocity grid to compute a piecewise constant reconstruction for the collisional part of the solution. The latter is added to a piecewise constant reconstruction of the non-collisional part of the solution, which in fact remains unchanged during the relaxation step. Numerical results show that the stochastic noise is significantly reduced at large Knudsen numbers with respect to the standard DSMC method. Indeed in this algorithm, the particle scheme is applied only on the collisional part of the solution, so only this fraction of the solution is affected by stochastic fluctuations. But since the collisional part of the solution reduces as the Knudsen number increases, stochastic noise reduces as well at large Knudsen numbers.

  7. A comparison of the lattice discrete particle method to the finite-element method and the K&C material model for simulating the static and dynamic response of concrete.

    SciTech Connect

    Smith, Jovanca J.; Bishop, Joseph E.

    2013-11-01

    This report summarizes the work performed by the graduate student Jovanca Smith during a summer internship in the summer of 2012 with the aid of mentor Joe Bishop. The projects were a two-part endeavor that focused on the use of the numerical model called the Lattice Discrete Particle Model (LDPM). The LDPM is a discrete meso-scale model currently used at Northwestern University and the ERDC to model the heterogeneous quasi-brittle material, concrete. In the first part of the project, LDPM was compared to the Karagozian and Case Concrete Model (K&C) used in Presto, an explicit dynamics finite-element code, developed at Sandia National Laboratories. In order to make this comparison, a series of quasi-static numerical experiments were performed, namely unconfined uniaxial compression tests on four varied cube specimen sizes, three-point bending notched experiments on three proportional specimen sizes, and six triaxial compression tests on a cylindrical specimen. The second part of this project focused on the application of LDPM to simulate projectile perforation on an ultra high performance concrete called CORTUF. This application illustrates the strengths of LDPM over traditional continuum models.

  8. Enhanced dielectric properties of poly(vinylidene fluoride) composites filled with nano iron oxide-deposited barium titanate hybrid particles

    NASA Astrophysics Data System (ADS)

    Zhang, Changhai; Chi, Qingguo; Dong, Jiufeng; Cui, Yang; Wang, Xuan; Liu, Lizhu; Lei, Qingquan

    2016-09-01

    We report enhancement of the dielectric permittivity of poly(vinylidene fluoride) (PVDF) generated by depositing magnetic iron oxide (Fe3O4) nanoparticles on the surface of barium titanate (BT) to fabricate BT–Fe3O4/PVDF composites. This process introduced an external magnetic field and the influences of external magnetic field on dielectric properties of composites were investigated systematically. The composites subjected to magnetic field treatment for 30 min at 60 °C exhibited the largest dielectric permittivity (385 at 100 Hz) when the BT–Fe3O4 concentration is approximately 33 vol.%. The BT–Fe3O4 suppressed the formation of a conducting path in the composite and induced low dielectric loss (0.3) and low conductivity (4.12 × 10‑9 S/cm) in the composite. Series-parallel model suggested that the enhanced dielectric permittivity of BT–Fe3O4/PVDF composites should arise from the ultrahigh permittivity of BT–Fe3O4 hybrid particles. However, the experimental results of the BT–Fe3O4/PVDF composites treated by magnetic field agree with percolation theory, which indicates that the enhanced dielectric properties of the BT–Fe3O4/PVDF composites originate from the interfacial polarization induced by the external magnetic field. This work provides a simple and effective way for preparing nanocomposites with enhanced dielectric properties for use in the electronics industry.

  9. Enhanced dielectric properties of poly(vinylidene fluoride) composites filled with nano iron oxide-deposited barium titanate hybrid particles

    PubMed Central

    Zhang, Changhai; Chi, Qingguo; Dong, Jiufeng; Cui, Yang; Wang, Xuan; Liu, Lizhu; Lei, Qingquan

    2016-01-01

    We report enhancement of the dielectric permittivity of poly(vinylidene fluoride) (PVDF) generated by depositing magnetic iron oxide (Fe3O4) nanoparticles on the surface of barium titanate (BT) to fabricate BT–Fe3O4/PVDF composites. This process introduced an external magnetic field and the influences of external magnetic field on dielectric properties of composites were investigated systematically. The composites subjected to magnetic field treatment for 30 min at 60 °C exhibited the largest dielectric permittivity (385 at 100 Hz) when the BT–Fe3O4 concentration is approximately 33 vol.%. The BT–Fe3O4 suppressed the formation of a conducting path in the composite and induced low dielectric loss (0.3) and low conductivity (4.12 × 10−9 S/cm) in the composite. Series-parallel model suggested that the enhanced dielectric permittivity of BT–Fe3O4/PVDF composites should arise from the ultrahigh permittivity of BT–Fe3O4 hybrid particles. However, the experimental results of the BT–Fe3O4/PVDF composites treated by magnetic field agree with percolation theory, which indicates that the enhanced dielectric properties of the BT–Fe3O4/PVDF composites originate from the interfacial polarization induced by the external magnetic field. This work provides a simple and effective way for preparing nanocomposites with enhanced dielectric properties for use in the electronics industry. PMID:27633958

  10. Enhanced dielectric properties of poly(vinylidene fluoride) composites filled with nano iron oxide-deposited barium titanate hybrid particles.

    PubMed

    Zhang, Changhai; Chi, Qingguo; Dong, Jiufeng; Cui, Yang; Wang, Xuan; Liu, Lizhu; Lei, Qingquan

    2016-01-01

    We report enhancement of the dielectric permittivity of poly(vinylidene fluoride) (PVDF) generated by depositing magnetic iron oxide (Fe3O4) nanoparticles on the surface of barium titanate (BT) to fabricate BT-Fe3O4/PVDF composites. This process introduced an external magnetic field and the influences of external magnetic field on dielectric properties of composites were investigated systematically. The composites subjected to magnetic field treatment for 30 min at 60 °C exhibited the largest dielectric permittivity (385 at 100 Hz) when the BT-Fe3O4 concentration is approximately 33 vol.%. The BT-Fe3O4 suppressed the formation of a conducting path in the composite and induced low dielectric loss (0.3) and low conductivity (4.12 × 10(-9) S/cm) in the composite. Series-parallel model suggested that the enhanced dielectric permittivity of BT-Fe3O4/PVDF composites should arise from the ultrahigh permittivity of BT-Fe3O4 hybrid particles. However, the experimental results of the BT-Fe3O4/PVDF composites treated by magnetic field agree with percolation theory, which indicates that the enhanced dielectric properties of the BT-Fe3O4/PVDF composites originate from the interfacial polarization induced by the external magnetic field. This work provides a simple and effective way for preparing nanocomposites with enhanced dielectric properties for use in the electronics industry. PMID:27633958

  11. Enhanced dielectric properties of poly(vinylidene fluoride) composites filled with nano iron oxide-deposited barium titanate hybrid particles.

    PubMed

    Zhang, Changhai; Chi, Qingguo; Dong, Jiufeng; Cui, Yang; Wang, Xuan; Liu, Lizhu; Lei, Qingquan

    2016-09-16

    We report enhancement of the dielectric permittivity of poly(vinylidene fluoride) (PVDF) generated by depositing magnetic iron oxide (Fe3O4) nanoparticles on the surface of barium titanate (BT) to fabricate BT-Fe3O4/PVDF composites. This process introduced an external magnetic field and the influences of external magnetic field on dielectric properties of composites were investigated systematically. The composites subjected to magnetic field treatment for 30 min at 60 °C exhibited the largest dielectric permittivity (385 at 100 Hz) when the BT-Fe3O4 concentration is approximately 33 vol.%. The BT-Fe3O4 suppressed the formation of a conducting path in the composite and induced low dielectric loss (0.3) and low conductivity (4.12 × 10(-9) S/cm) in the composite. Series-parallel model suggested that the enhanced dielectric permittivity of BT-Fe3O4/PVDF composites should arise from the ultrahigh permittivity of BT-Fe3O4 hybrid particles. However, the experimental results of the BT-Fe3O4/PVDF composites treated by magnetic field agree with percolation theory, which indicates that the enhanced dielectric properties of the BT-Fe3O4/PVDF composites originate from the interfacial polarization induced by the external magnetic field. This work provides a simple and effective way for preparing nanocomposites with enhanced dielectric properties for use in the electronics industry.

  12. Synthesis and characterization of PVP-capped ZnO particles and its blend with poly(3-hexylthiophene) for hybrid solar cells application

    NASA Astrophysics Data System (ADS)

    Yuliah, Yayah; Bahtiar, Ayi

    2013-09-01

    ZnO nanoparticles (ZnO-NPs) agglomeration has been a long main problem on its utilization as acceptor materials of hybrid solar cell using blend of conjugated polymer poly(3-hexylthiophene) or P3HT and ZnO-NPs. Numbers of ZnO nanoparticle agglomeration lead to inhomogeneity of blend film morphology. This agglomeration causes ineffective electron transport within ZnO-NP, and thus lowers power conversion efficiency of hybrid solar cell. In this work, the ZnO particles were capped by PVP (poly-4-vinylpyrrolidone) to reduce agglomeration of ZnO particle and to improve homogeneity of blend P3HTZnO particles film. We used two different type of capping; first capping was applied during the synthesis of ZnO and second the capping was carried out after synthesis of ZnO. The ZnO particles were synthesized using sol-gel method at low temperature (27°C). We have found that the surface morphology of blend films which was ZnO-capped after synthesis is more homogeneous than that of during synthesis.

  13. Model for particle masses, flavor mixing, and {ital CP} violation, based on spontaneously broken discrete chiral symmetry as the origin of families

    SciTech Connect

    Adler, S.L.

    1999-01-01

    We construct extensions of the standard model based on the hypothesis that Higgs bosons also exhibit a family structure and that the flavor weak eigenstates in the three families are distinguished by a discrete Z{sub 6} chiral symmetry that is spontaneously broken by the Higgs sector. We study in detail at the tree level models with three Higgs doublets and with six Higgs doublets comprising two weakly coupled sets of three. In a leading approximation of S{sub 3} cyclic permutation symmetry the three-Higgs-doublet model gives a {open_quotes}democratic{close_quotes} mass matrix of rank 1, while the six-Higgs-doublet model gives either a rank-1 mass matrix or, in the case when it spontaneously violates {ital CP}, a rank-2 mass matrix corresponding to nonzero second family masses. In both models, the CKM matrix is exactly unity in the leading approximation. Allowing small explicit violations of cyclic permutation symmetry generates small first family masses in the six-Higgs-doublet model, and first and second family masses in the three-Higgs-doublet model, and gives a nontrivial CKM matrix in which the mixings of the first and second family quarks are naturally larger than mixings involving the third family. Complete numerical fits are given for both models, flavor-changing neutral current constraints are discussed in detail, and the issues of unification of couplings and neutrino masses are addressed. On a technical level, our analysis uses the theory of circulant and retrocirculant matrices, the relevant parts of which are reviewed. {copyright} {ital 1998} {ital The American Physical Society}

  14. Stable discrete representation of relativistically drifting plasmas

    NASA Astrophysics Data System (ADS)

    Kirchen, M.; Lehe, R.; Godfrey, B. B.; Dornmair, I.; Jalas, S.; Peters, K.; Vay, J.-L.; Maier, A. R.

    2016-10-01

    Representing the electrodynamics of relativistically drifting particle ensembles in discrete, co-propagating Galilean coordinates enables the derivation of a Particle-In-Cell algorithm that is intrinsically free of the numerical Cherenkov instability for plasmas flowing at a uniform velocity. Application of the method is shown by modeling plasma accelerators in a Lorentz-transformed optimal frame of reference.

  15. Particle-Film Plasmons on Periodic Silver Film over Nanosphere (AgFON): A Hybrid Plasmonic Nanoarchitecture for Surface-Enhanced Raman Spectroscopy.

    PubMed

    Lee, Jiwon; Zhang, Qianpeng; Park, Seungyoung; Choe, Ayoung; Fan, Zhiyong; Ko, Hyunhyub

    2016-01-13

    Plasmonic systems based on particle-film plasmonic couplings have recently attracted great attention because of the significantly enhanced electric field at the particle-film gaps. Here, we introduce a hybrid plasmonic architecture utilizing combined plasmonic effects of particle-film gap plasmons and silver film over nanosphere (AgFON) substrates. When gold nanoparticles (AuNPs) are assembled on AgFON substrates with controllable particle-film gap distances, the AuNP-AgFON system supports multiple plasmonic couplings from interparticle, particle-film, and crevice gaps, resulting in a huge surface-enhanced Raman spectroscopy (SERS) effect. We show that the periodicity of AgFON substrates and the particle-film gaps greatly affects the surface plasmon resonances, and thus, the SERS effects due to the interplay between multiple plasmonic couplings. The optimally designed AuNP-AgFON substrate shows a SERS enhancement of 233 times compared to the bare AgFON substrate. The ultrasensitive SERS sensing capability is also demonstrated by detecting glutathione, a neurochemical molecule that is an important antioxidant, down to the 10 pM level.

  16. Classification of Medical Datasets Using SVMs with Hybrid Evolutionary Algorithms Based on Endocrine-Based Particle Swarm Optimization and Artificial Bee Colony Algorithms.

    PubMed

    Lin, Kuan-Cheng; Hsieh, Yi-Hsiu

    2015-10-01

    The classification and analysis of data is an important issue in today's research. Selecting a suitable set of features makes it possible to classify an enormous quantity of data quickly and efficiently. Feature selection is generally viewed as a problem of feature subset selection, such as combination optimization problems. Evolutionary algorithms using random search methods have proven highly effective in obtaining solutions to problems of optimization in a diversity of applications. In this study, we developed a hybrid evolutionary algorithm based on endocrine-based particle swarm optimization (EPSO) and artificial bee colony (ABC) algorithms in conjunction with a support vector machine (SVM) for the selection of optimal feature subsets for the classification of datasets. The results of experiments using specific UCI medical datasets demonstrate that the accuracy of the proposed hybrid evolutionary algorithm is superior to that of basic PSO, EPSO and ABC algorithms, with regard to classification accuracy using subsets with a reduced number of features.

  17. Effect of surface fluorination of TiO2 particles on photocatalitytic activity of a hybrid multilayer coating obtained by sol-gel method.

    PubMed

    Zhu, Yunfeng; Piscitelli, Filomena; Buonocore, Giovanna G; Lavorgna, Marino; Amendola, Eugenio; Ambrosio, Luigi

    2012-01-01

    A multilayer photoactive coating containing surface fluorinated TiO(2) nanoparticles and hybrid matrices by sol gel approach based on renewable chitosan was applied on poly(lactic acid) (PLA) film by a step wise spin-coating method. The upper photoactive layer contains nano-sized functionalized TiO(2) particles dispersed in a siloxane based matrix. For the purpose of improving TiO(2) dispersion at the air interface coating surface, TiO(2) nanoparticles were modified by silane coupling agent 1H,1H,2H,2H-perfluorooctyltriethoxysilane (FTS) with fluoro-organic side chains. An additional hybrid material consisting of chitosan (CS) cross-linked with 3-glycidyloxypropyl trimethoxy silane (GOTMS) was applied as interlayer between the PLA substrate and the upper photoactive coating to increase the adhesion and reciprocal affinity. The multilayer TiO(2)/CS-GOTMS coatings on PLA films showed a thickness of ~4-6 μm and resulted highly transparent. Their structure was exhaustively characterized by SEM, optical microscope, UV-vis spectroscopy and contact angle measurements. The photocatalytic activity of the multilayer coatings were investigated using methyl orange (MeO) as a target pollutant; the results showed that PLA films coated with surface fluorinated particles exhibit higher activity than films with neat particles, because of a better dispersion of TiO(2) particles. The mechanical properties of PLA and films coated with fluorinated particles, irradiated by UV light were also investigated; the results showed that the degradation of PLA substrate was markedly suppressed because of the UV adsorptive action of the multilayer coating. PMID:22117597

  18. DNA-Origami-Directed Self-Assembly of Discrete Silver-Nanoparticle Architectures

    SciTech Connect

    Pal, Suchetan; Deng, Zhengtao; Ding, Baoquan; Yan, Hao; Liu, Yan

    2010-03-16

    We report a bottom-up method for the fabrication of discrete, well-ordered AgNP nanoarchitectures on self-assembled DNA origami structures of triangular shape by using AgNPs (20 nm in diameter) conjugated with chimeric phosphorothioated DNA (ps-po DNA) as building blocks. Discrete monomeric, dimeric, and trimeric AgNP structures and a AgNP–AuNP hybrid structure could be constructed reliably in high yield. We demonstrate that the center-to-center distance between adjacent AgNPs can be precisely tuned from 94 to 29 nm, whereby the distance distribution is limited by the size distribution of the nanoparticles. The self-assembly of discrete AgNP and AgNP–AuNP nanoarchitectures by using rationally designed DNA templates enabled us to control some of the properties that are essential for hierarchical nanoparticle assembly. These properties include but are not limited to the spatial relationship between the particles and the identity of the particles. The system described herein could potentially be used to gain better insight into particle–particle interactions. Systematic studies with this objective are underway. Although more systematic investigations (e.g. spectroscopic studies combined with theoretical simulation of the assembled structures) are needed to identify the photonic properties of the spatially controlled AgNP architectures, we see no fundamental limitation now to the assembly of target structures.

  19. On the definition of discrete hydrodynamic variables.

    PubMed

    Español, Pep; Zúñiga, Ignacio

    2009-10-28

    The Green-Kubo formula for discrete hydrodynamic variables involves information about not only the fluid transport coefficients but also about discrete versions of the differential operators that govern the evolution of the discrete variables. This gives an intimate connection between discretization procedures in fluid dynamics and coarse-graining procedures used to obtain hydrodynamic behavior of molecular fluids. We observed that a natural definition of discrete hydrodynamic variables in terms of Voronoi cells leads to a Green-Kubo formula which is divergent, rendering the full coarse-graining strategy useless. In order to understand this subtle issue, in the present paper we consider the coarse graining of noninteracting Brownian particles. The discrete hydrodynamic variable for this problem is the number of particles within Voronoi cells. Thanks to the simplicity of the model we spot the origin of the singular behavior of the correlation functions. We offer an alternative definition, based on the concept of a Delaunay cell that behaves properly, suggesting the use of the Delaunay construction for the coarse graining of molecular fluids at the discrete hydrodynamic level.

  20. Development of antimicrobial water filtration hybrid material from bio source calcium carbonate and silver nanoparticles

    NASA Astrophysics Data System (ADS)

    Apalangya, Vitus; Rangari, Vijaya; Tiimob, Boniface; Jeelani, Shaik; Samuel, Temesgen

    2014-03-01

    Biobased calcium carbonate and silver hybrid nanoparticles were synthesized using a simple mechanochemical milling technique. The XRD spectrum showed that the hybrid materials is composed of crystalline calcite and silver nanoparticles. The TEM results indicated that the silver nanoparticles are discrete, uncapped and well stabilized in the surface of the eggshell derived calcium carbonate particles. The silver nanoparticles are spherical in shape and 5-20 nm in size. The SEM studies indicated that the eggshells are in micron size with the silver nanoparticle embedded in their surface. The hybrid eggshell/silver nanocomposite exhibited superior inhibition of E. coli growth using the Kirby-Bauer discs diffusion assay and comparing the zone of inhibition around the filter paper disc impregnated with the hybrid particles against pristine silver nanoparticles.

  1. Principles of Discrete Time Mechanics

    NASA Astrophysics Data System (ADS)

    Jaroszkiewicz, George

    2014-04-01

    1. Introduction; 2. The physics of discreteness; 3. The road to calculus; 4. Temporal discretization; 5. Discrete time dynamics architecture; 6. Some models; 7. Classical cellular automata; 8. The action sum; 9. Worked examples; 10. Lee's approach to discrete time mechanics; 11. Elliptic billiards; 12. The construction of system functions; 13. The classical discrete time oscillator; 14. Type 2 temporal discretization; 15. Intermission; 16. Discrete time quantum mechanics; 17. The quantized discrete time oscillator; 18. Path integrals; 19. Quantum encoding; 20. Discrete time classical field equations; 21. The discrete time Schrodinger equation; 22. The discrete time Klein-Gordon equation; 23. The discrete time Dirac equation; 24. Discrete time Maxwell's equations; 25. The discrete time Skyrme model; 26. Discrete time quantum field theory; 27. Interacting discrete time scalar fields; 28. Space, time and gravitation; 29. Causality and observation; 30. Concluding remarks; Appendix A. Coherent states; Appendix B. The time-dependent oscillator; Appendix C. Quaternions; Appendix D. Quantum registers; References; Index.

  2. Hybrid support vector regression and autoregressive integrated moving average models improved by particle swarm optimization for property crime rates forecasting with economic indicators.

    PubMed

    Alwee, Razana; Shamsuddin, Siti Mariyam Hj; Sallehuddin, Roselina

    2013-01-01

    Crimes forecasting is an important area in the field of criminology. Linear models, such as regression and econometric models, are commonly applied in crime forecasting. However, in real crimes data, it is common that the data consists of both linear and nonlinear components. A single model may not be sufficient to identify all the characteristics of the data. The purpose of this study is to introduce a hybrid model that combines support vector regression (SVR) and autoregressive integrated moving average (ARIMA) to be applied in crime rates forecasting. SVR is very robust with small training data and high-dimensional problem. Meanwhile, ARIMA has the ability to model several types of time series. However, the accuracy of the SVR model depends on values of its parameters, while ARIMA is not robust to be applied to small data sets. Therefore, to overcome this problem, particle swarm optimization is used to estimate the parameters of the SVR and ARIMA models. The proposed hybrid model is used to forecast the property crime rates of the United State based on economic indicators. The experimental results show that the proposed hybrid model is able to produce more accurate forecasting results as compared to the individual models.

  3. Hybrid Support Vector Regression and Autoregressive Integrated Moving Average Models Improved by Particle Swarm Optimization for Property Crime Rates Forecasting with Economic Indicators

    PubMed Central

    Alwee, Razana; Hj Shamsuddin, Siti Mariyam; Sallehuddin, Roselina

    2013-01-01

    Crimes forecasting is an important area in the field of criminology. Linear models, such as regression and econometric models, are commonly applied in crime forecasting. However, in real crimes data, it is common that the data consists of both linear and nonlinear components. A single model may not be sufficient to identify all the characteristics of the data. The purpose of this study is to introduce a hybrid model that combines support vector regression (SVR) and autoregressive integrated moving average (ARIMA) to be applied in crime rates forecasting. SVR is very robust with small training data and high-dimensional problem. Meanwhile, ARIMA has the ability to model several types of time series. However, the accuracy of the SVR model depends on values of its parameters, while ARIMA is not robust to be applied to small data sets. Therefore, to overcome this problem, particle swarm optimization is used to estimate the parameters of the SVR and ARIMA models. The proposed hybrid model is used to forecast the property crime rates of the United State based on economic indicators. The experimental results show that the proposed hybrid model is able to produce more accurate forecasting results as compared to the individual models. PMID:23766729

  4. Hybrid support vector regression and autoregressive integrated moving average models improved by particle swarm optimization for property crime rates forecasting with economic indicators.

    PubMed

    Alwee, Razana; Shamsuddin, Siti Mariyam Hj; Sallehuddin, Roselina

    2013-01-01

    Crimes forecasting is an important area in the field of criminology. Linear models, such as regression and econometric models, are commonly applied in crime forecasting. However, in real crimes data, it is common that the data consists of both linear and nonlinear components. A single model may not be sufficient to identify all the characteristics of the data. The purpose of this study is to introduce a hybrid model that combines support vector regression (SVR) and autoregressive integrated moving average (ARIMA) to be applied in crime rates forecasting. SVR is very robust with small training data and high-dimensional problem. Meanwhile, ARIMA has the ability to model several types of time series. However, the accuracy of the SVR model depends on values of its parameters, while ARIMA is not robust to be applied to small data sets. Therefore, to overcome this problem, particle swarm optimization is used to estimate the parameters of the SVR and ARIMA models. The proposed hybrid model is used to forecast the property crime rates of the United State based on economic indicators. The experimental results show that the proposed hybrid model is able to produce more accurate forecasting results as compared to the individual models. PMID:23766729

  5. Effects of temperature and particles concentration on the dynamic viscosity of MgO-MWCNT/ethylene glycol hybrid nanofluid: Experimental study

    NASA Astrophysics Data System (ADS)

    Soltani, Omid; Akbari, Mohammad

    2016-10-01

    In this paper, the effects of temperature and particles concentration on the dynamic viscosity of MgO-MWCNT/ethylene glycol hybrid nanofluid is examined. The experiments carried out in the solid volume fraction range of 0 to 1.0% under the temperature ranging from 30 °C to 60 °C. The results showed that the hybrid nanofluid behaves as a Newtonian fluid for all solid volume fractions and temperatures considered. The measurements also indicated that the dynamic viscosity increases with increasing the solid volume fraction and decreases with the temperature rising. The relative viscosity revealed that when the solid volume fraction enhances from 0.1 to 1%, the dynamic viscosity increases up to 168%. Finally, using experimental data, in order to predict the dynamic viscosity of MgO-MWCNT/ethylene glycol hybrid nanofluids, a new correlation has been suggested. The comparisons between the correlation outputs and experimental results showed that the suggested correlation has an acceptable accuracy.

  6. The discrete regime of flame propagation

    NASA Astrophysics Data System (ADS)

    Tang, Francois-David; Goroshin, Samuel; Higgins, Andrew

    The propagation of laminar dust flames in iron dust clouds was studied in a low-gravity envi-ronment on-board a parabolic flight aircraft. The elimination of buoyancy-induced convection and particle settling permitted measurements of fundamental combustion parameters such as the burning velocity and the flame quenching distance over a wide range of particle sizes and in different gaseous mixtures. The discrete regime of flame propagation was observed by substitut-ing nitrogen present in air with xenon, an inert gas with a significantly lower heat conductivity. Flame propagation in the discrete regime is controlled by the heat transfer between neighbor-ing particles, rather than by the particle burning rate used by traditional continuum models of heterogeneous flames. The propagation mechanism of discrete flames depends on the spa-tial distribution of particles, and thus such flames are strongly influenced by local fluctuations in the fuel concentration. Constant pressure laminar dust flames were observed inside 70 cm long, 5 cm diameter Pyrex tubes. Equally-spaced plate assemblies forming rectangular chan-nels were placed inside each tube to determine the quenching distance defined as the minimum channel width through which a flame can successfully propagate. High-speed video cameras were used to measure the flame speed and a fiber optic spectrometer was used to measure the flame temperature. Experimental results were compared with predictions obtained from a numerical model of a three-dimensional flame developed to capture both the discrete nature and the random distribution of particles in the flame. Though good qualitative agreement was obtained between model predictions and experimental observations, residual g-jitters and the short reduced-gravity periods prevented further investigations of propagation limits in the dis-crete regime. The full exploration of the discrete flame phenomenon would require high-quality, long duration reduced gravity environment

  7. Validation of comprehensive magnetohydrodynamic hybrid simulations for Alfvén eigenmode induced energetic particle transport in DIII-D plasmas

    NASA Astrophysics Data System (ADS)

    Todo, Y.; Van Zeeland, M. A.; Bierwage, A.; Heidbrink, W. W.; Austin, M. E.

    2015-07-01

    A multi-phase simulation, which is a combination of classical simulation and hybrid simulation for energetic particles interacting with a magnetohydrodynamic (MHD) fluid including neutral beam injection, slowing-down, and pitch angle scattering, is applied to DIII-D discharge #142111 where the fast ion spatial profile is significantly flattened due to multiple Alfvén eigenmodes (AEs). The large fast ion pressure profile flattening observed experimentally is successfully reproduced by these first of a kind comprehensive simulations. Temperature fluctuations due to three of the dominant toroidal Alfvén eigenmodes in the simulation results are compared in detail with electron cyclotron emission measurements in the experiment. It is demonstrated that the temperature fluctuation profile and the phase profile are in very good agreement with the measurement, and the amplitude is also in agreement within a factor of two. This level of agreement validates the multi-phase hybrid simulation for the prediction of AE activity and alpha particle transport in burning plasmas.

  8. High energy particles at Mars and Venus: Phobos-2, Mars Express and Venus Express observations and their interpretation by hybrid model simulations

    NASA Astrophysics Data System (ADS)

    McKenna-Lawlor, Susan; Kallio, Esa; Fram, Rudy A.; Alho, Markku; Jarvinen, Riku; Dyadechkin, Sergey; Wedlund, Cyril Simon; Zhang, Tielong; Collinson, Glyn A.; Futaana, Yoshifumi

    2013-04-01

    Mars and Venus can both be reached by Solar Energetic Particles (SEPs). Such high energy particles (protons, multiply charged heavy ions, electrons) penetrate the upper atmospheres of Mars and Venus because, in contrast to Earth, these bodies do not have a significant, global, intrinsic magnetic field to exclude them. One especially well documented, complex and prolonged SEP took in place in early 1989 (Solar Cycle 23) when the Phobos-2 spacecraft was orbiting Mars. This spacecraft had a dedicated high energy particle instrument onboard (SLED), which measured particles with energies in the keV range up to a few tens of MeV. There was in addition a magnetometer as well as solar wind plasma detectors onboard which together provided complementary data to support contemporaneous studies of the background SEP environment. Currently, while the Sun is displaying maximum activity (Solar Cycle 24), Mars and Venus are being individually monitored by instrumentation flown onboard the Mars Express (MEX) and Venus Express (VEX) spacecraft. Neither of these spacecraft carry a high energy particle instrument but their Analyzer of Space Plasmas and Energetic Atoms (ASPERA) experiments (ASPERA-3 on MEX and ASPERA-4 on VEX), can be used to study SEPs integrated over E ≥ ~30 MeV which penetrate the instrument hardware and form background counts in the plasma data. In the present work we present SEP events measured at Mars and Venus based on Phobos-2, 1989 data and on, more recent, MEX and VEX (identified from particle background) observations. We further introduce numerical global SEP simulations of the measured events based on 3-D self-consistent hybrid models (HYB-Mars and HYB-Venus). Through comparing the in situ SEP observations with these simulations, new insights are provided into the properties of the measured SEPs as well as into how their individual planetary bow shocks and magnetospheres affect the characteristics of their ambient Martian and Venusian SEP environments.

  9. A hybrid chip based on aerodynamics and electrostatics for the size-dependent classification of ultrafine and nano particles.

    PubMed

    Kim, Yong-Ho; Park, Dongho; Hwang, Jungho; Kim, Yong-Jun

    2009-09-21

    Conventional virtual impactors experience a large pressure drop when they classify particles according to size, in particular ultrafine particles smaller than 100 nm in diameter. Therefore, most virtual impactors have been used to classify particles larger than 100 nm. Their cut-off diameters are also fixed by the geometry of their flow channels. In the proposed virtual impactor, particles smaller than 100 nm are accelerated by applying DC potentials to an integrated electrode pair. By the electrical acceleration, the large pressure drop could be significantly decreased and new cut-off diameters smaller than 100 nm could be successfully added. The geometric cut-off diameter (GCD) of the proposed virtual impactor was designed to be 1.0 microm. Performances including the GCD and wall loss were examined by classifying dioctyl sebacate of 100 to 600 nm in size and carbon particles of 0.6 to 10 microm in size. The GCD was measured to be 0.95 microm, and the wall loss was highest at 1.1 microm. To add new cut-off diameters, monodisperse NaCl particles ranging from 15 to 70 nm were classified using the proposed virtual impactor with applying a DC potential of 0.25 to 3.0 kV. In this range of the potential, the new cut-off diameters ranging from 15 to 35 nm was added.

  10. Implementation of a hybrid particle code with a PIC description in r–z and a gridless description in ϕ into OSIRIS

    SciTech Connect

    Davidson, A.; Tableman, A.; An, W.; Tsung, F.S.; Lu, W.; Vieira, J.; Silva, L.O.

    2015-01-15

    For many plasma physics problems, three-dimensional and kinetic effects are very important. However, such simulations are very computationally intensive. Fortunately, there is a class of problems for which there is nearly azimuthal symmetry and the dominant three-dimensional physics is captured by the inclusion of only a few azimuthal harmonics. Recently, it was proposed [1] to model one such problem, laser wakefield acceleration, by expanding the fields and currents in azimuthal harmonics and truncating the expansion. The complex amplitudes of the fundamental and first harmonic for the fields were solved on an r–z grid and a procedure for calculating the complex current amplitudes for each particle based on its motion in Cartesian geometry was presented using a Marder's correction to maintain the validity of Gauss's law. In this paper, we describe an implementation of this algorithm into OSIRIS using a rigorous charge conserving current deposition method to maintain the validity of Gauss's law. We show that this algorithm is a hybrid method which uses a particles-in-cell description in r–z and a gridless description in ϕ. We include the ability to keep an arbitrary number of harmonics and higher order particle shapes. Examples for laser wakefield acceleration, plasma wakefield acceleration, and beam loading are also presented and directions for future work are discussed.

  11. Computational Fluid Dynamics Study of Molten Steel Flow Patterns and Particle-Wall Interactions Inside a Slide-Gate Nozzle by a Hybrid Turbulent Model

    NASA Astrophysics Data System (ADS)

    Mohammadi-Ghaleni, Mahdi; Asle Zaeem, Mohsen; Smith, Jeffrey D.; O'Malley, Ronald

    2016-10-01

    Melt flow patterns and turbulence inside a slide-gate throttled submerged entry nozzle (SEN) were studied using Detached-Eddy Simulation (DES) model, which is a combination of Reynolds-Averaged Navier-Stokes (RANS) and Large-Eddy Simulation (LES) models. The DES switching criterion between RANS and LES was investigated to closely reproduce the flow structures of low and high turbulence regions similar to RANS and LES simulations, respectively. The melt flow patterns inside the nozzle were determined by k- ɛ (a RANS model), LES, and DES turbulent models, and convergence studies were performed to ensure reliability of the results. Results showed that the DES model has significant advantages over the standard k- ɛ model in transient simulations and in regions containing flow separation from the nozzle surface. Moreover, due to applying a hybrid approach, DES uses a RANS model at wall boundaries which resolves the extremely fine mesh requirement of LES simulations, and therefore it is computationally more efficient. Investigation of particle distribution inside the nozzle and particle adhesion to the nozzle wall also reveals that the DES model simulations predict more particle-wall interactions compared to LES model.

  12. Computational Fluid Dynamics Study of Molten Steel Flow Patterns and Particle-Wall Interactions Inside a Slide-Gate Nozzle by a Hybrid Turbulent Model

    NASA Astrophysics Data System (ADS)

    Mohammadi-Ghaleni, Mahdi; Asle Zaeem, Mohsen; Smith, Jeffrey D.; O'Malley, Ronald

    2016-06-01

    Melt flow patterns and turbulence inside a slide-gate throttled submerged entry nozzle (SEN) were studied using Detached-Eddy Simulation (DES) model, which is a combination of Reynolds-Averaged Navier-Stokes (RANS) and Large-Eddy Simulation (LES) models. The DES switching criterion between RANS and LES was investigated to closely reproduce the flow structures of low and high turbulence regions similar to RANS and LES simulations, respectively. The melt flow patterns inside the nozzle were determined by k-ɛ (a RANS model), LES, and DES turbulent models, and convergence studies were performed to ensure reliability of the results. Results showed that the DES model has significant advantages over the standard k-ɛ model in transient simulations and in regions containing flow separation from the nozzle surface. Moreover, due to applying a hybrid approach, DES uses a RANS model at wall boundaries which resolves the extremely fine mesh requirement of LES simulations, and therefore it is computationally more efficient. Investigation of particle distribution inside the nozzle and particle adhesion to the nozzle wall also reveals that the DES model simulations predict more particle-wall interactions compared to LES model.

  13. Discrete Mathematics Re "Tooled."

    ERIC Educational Resources Information Center

    Grassl, Richard M.; Mingus, Tabitha T. Y.

    1999-01-01

    Indicates the importance of teaching discrete mathematics. Describes how the use of technology can enhance the teaching and learning of discrete mathematics. Explorations using Excel, Derive, and the TI-92 proved how preservice and inservice teachers experienced a new dimension in problem solving and discovery. (ASK)

  14. Discrete Element Modeling

    SciTech Connect

    Morris, J; Johnson, S

    2007-12-03

    The Distinct Element Method (also frequently referred to as the Discrete Element Method) (DEM) is a Lagrangian numerical technique where the computational domain consists of discrete solid elements which interact via compliant contacts. This can be contrasted with Finite Element Methods where the computational domain is assumed to represent a continuum (although many modern implementations of the FEM can accommodate some Distinct Element capabilities). Often the terms Discrete Element Method and Distinct Element Method are used interchangeably in the literature, although Cundall and Hart (1992) suggested that Discrete Element Methods should be a more inclusive term covering Distinct Element Methods, Displacement Discontinuity Analysis and Modal Methods. In this work, DEM specifically refers to the Distinct Element Method, where the discrete elements interact via compliant contacts, in contrast with Displacement Discontinuity Analysis where the contacts are rigid and all compliance is taken up by the adjacent intact material.

  15. Synchronous Discrete Harmonic Oscillator

    SciTech Connect

    Antippa, Adel F.; Dubois, Daniel M.

    2008-10-17

    We introduce the synchronous discrete harmonic oscillator, and present an analytical, numerical and graphical study of its characteristics. The oscillator is synchronous when the time T for one revolution covering an angle of 2{pi} in phase space, is an integral multiple N of the discrete time step {delta}t. It is fully synchronous when N is even. It is pseudo-synchronous when T/{delta}t is rational. In the energy conserving hyperincursive representation, the phase space trajectories are perfectly stable at all time scales, and in both synchronous and pseudo-synchronous modes they cycle through a finite number of phase space points. Consequently, both the synchronous and the pseudo-synchronous hyperincursive modes of time-discretization provide a physically realistic and mathematically coherent, procedure for dynamic, background independent, discretization of spacetime. The procedure is applicable to any stable periodic dynamical system, and provokes an intrinsic correlation between space and time, whereby space-discretization is a direct consequence of background-independent time-discretization. Hence, synchronous discretization moves the formalism of classical mechanics towards that of special relativity. The frequency of the hyperincursive discrete harmonic oscillator is ''blue shifted'' relative to its continuum counterpart. The frequency shift has the precise value needed to make the speed of the system point in phase space independent of the discretizing time interval {delta}t. That is the speed of the system point is the same on the polygonal (in the discrete case) and the circular (in the continuum case) phase space trajectories.

  16. An efficient mixed-precision, hybrid CPU-GPU implementation of a nonlinearly implicit one-dimensional particle-in-cell algorithm

    SciTech Connect

    Chen, Guangye; Chacon, Luis; Barnes, Daniel C

    2012-01-01

    Recently, a fully implicit, energy- and charge-conserving particle-in-cell method has been developed for multi-scale, full-f kinetic simulations [G. Chen, et al., J. Comput. Phys. 230, 18 (2011)]. The method employs a Jacobian-free Newton-Krylov (JFNK) solver and is capable of using very large timesteps without loss of numerical stability or accuracy. A fundamental feature of the method is the segregation of particle orbit integrations from the field solver, while remaining fully self-consistent. This provides great flexibility, and dramatically improves the solver efficiency by reducing the degrees of freedom of the associated nonlinear system. However, it requires a particle push per nonlinear residual evaluation, which makes the particle push the most time-consuming operation in the algorithm. This paper describes a very efficient mixed-precision, hybrid CPU-GPU implementation of the implicit PIC algorithm. The JFNK solver is kept on the CPU (in double precision), while the inherent data parallelism of the particle mover is exploited by implementing it in single-precision on a graphics processing unit (GPU) using CUDA. Performance-oriented optimizations, with the aid of an analytical performance model, the roofline model, are employed. Despite being highly dynamic, the adaptive, charge-conserving particle mover algorithm achieves up to 300 400 GOp/s (including single-precision floating-point, integer, and logic operations) on a Nvidia GeForce GTX580, corresponding to 20 25% absolute GPU efficiency (against the peak theoretical performance) and 50-70% intrinsic efficiency (against the algorithm s maximum operational throughput, which neglects all latencies). This is about 200-300 times faster than an equivalent serial CPU implementation. When the single-precision GPU particle mover is combined with a double-precision CPU JFNK field solver, overall performance gains 100 vs. the double-precision CPU-only serial version are obtained, with no apparent loss of

  17. Hybrid model for an enzymatic reactor: hydrolysis of cheese whey proteins by alcalase immobilized in agarose gel particles.

    PubMed

    Sousa, Ruy; Resende, Mariam M; Giordano, Raquel L C; Giordano, Roberto C

    2003-01-01

    Cheese whey proteolysis, carried out by immobilized enzymes, can either change or evidence functional properties of the produced peptides, increasing the potential applications of this byproduct of the dairy industry. Optimization and scale-up of the enzymatic reactor relies on its mathematical model-a set of mass balance equations, with reaction rates usually given by Michaelis-Menten-like kinetics; no information about the distribution of peptides' molecular sizes is supplied. In this article, a hybrid model of a batch enzymatic reactor is presented, consisting of differential mass balances coupled to a "neural-kinetic model," which provides the molecular weight distributions of the resulting peptides. PMID:12721464

  18. A deterministic discrete ordinates transport proxy application

    SciTech Connect

    2014-06-03

    Kripke is a simple 3D deterministic discrete ordinates (Sn) particle transport code that maintains the computational load and communications pattern of a real transport code. It is intended to be a research tool to explore different data layouts, new programming paradigms and computer architectures.

  19. Registration procedure for spatial correlation of physical energy deposition of particle irradiation and cellular response utilizing cell-fluorescent ion track hybrid detectors.

    PubMed

    Niklas, M; Zimmermann, F; Schlegel, J; Schwager, C; Debus, J; Jäkel, O; Abdollahi, A; Greilich, S

    2016-09-01

    The hybrid technology cell-fluorescent ion track hybrid detector (Cell-Fit-HD) enables the investigation of radiation-related cellular events along single ion tracks on the subcellular scale in clinical ion beams. The Cell-Fit-HD comprises a fluorescent nuclear track detector (FNTD, the physical compartment), a device for individual particle detection and a substrate for viable cell-coating, i.e. the biological compartment. To date both compartments have been imaged sequentially in situ by confocal laser scanning microscopy (CLSM). This is yet in conflict with a functional read-out of the Cell-Fit-HD utilizing a fast live-cell imaging of the biological compartment with low phototoxicity on greater time scales. The read-out of the biological from the physical compartment was uncoupled. A read-out procedure was developed to image the cell layer by conventional widefield microscopy whereas the FNTD was imaged by CLSM. Point mapping registration of the confocal and widefield imaging data was performed. Non-fluorescent crystal defects (spinels) visible in both read-outs were used as control point pairs. The accuracy achieved was on the sub-µm scale. The read-out procedure by widefield microscopy does not impair the unique ability of spatial correlation by the Cell-Fit-HD. The uncoupling will enlarge the application potential of the hybrid technology significantly. The registration allows for an ultimate correlation of microscopic physical beam parameters and cell kinetics on greater time scales. The method reported herein will be instrumental for the introduction of a novel generation of compact detectors facilitating biodosimetric research towards high-throughput analysis.

  20. Registration procedure for spatial correlation of physical energy deposition of particle irradiation and cellular response utilizing cell-fluorescent ion track hybrid detectors

    NASA Astrophysics Data System (ADS)

    Niklas, M.; Zimmermann, F.; Schlegel, J.; Schwager, C.; Debus, J.; Jäkel, O.; Abdollahi, A.; Greilich, S.

    2016-09-01

    The hybrid technology cell-fluorescent ion track hybrid detector (Cell-Fit-HD) enables the investigation of radiation-related cellular events along single ion tracks on the subcellular scale in clinical ion beams. The Cell-Fit-HD comprises a fluorescent nuclear track detector (FNTD, the physical compartment), a device for individual particle detection and a substrate for viable cell-coating, i.e. the biological compartment. To date both compartments have been imaged sequentially in situ by confocal laser scanning microscopy (CLSM). This is yet in conflict with a functional read-out of the Cell-Fit-HD utilizing a fast live-cell imaging of the biological compartment with low phototoxicity on greater time scales. The read-out of the biological from the physical compartment was uncoupled. A read-out procedure was developed to image the cell layer by conventional widefield microscopy whereas the FNTD was imaged by CLSM. Point mapping registration of the confocal and widefield imaging data was performed. Non-fluorescent crystal defects (spinels) visible in both read-outs were used as control point pairs. The accuracy achieved was on the sub-µm scale. The read-out procedure by widefield microscopy does not impair the unique ability of spatial correlation by the Cell-Fit-HD. The uncoupling will enlarge the application potential of the hybrid technology significantly. The registration allows for an ultimate correlation of microscopic physical beam parameters and cell kinetics on greater time scales. The method reported herein will be instrumental for the introduction of a novel generation of compact detectors facilitating biodosimetric research towards high-throughput analysis.

  1. Registration procedure for spatial correlation of physical energy deposition of particle irradiation and cellular response utilizing cell-fluorescent ion track hybrid detectors.

    PubMed

    Niklas, M; Zimmermann, F; Schlegel, J; Schwager, C; Debus, J; Jäkel, O; Abdollahi, A; Greilich, S

    2016-09-01

    The hybrid technology cell-fluorescent ion track hybrid detector (Cell-Fit-HD) enables the investigation of radiation-related cellular events along single ion tracks on the subcellular scale in clinical ion beams. The Cell-Fit-HD comprises a fluorescent nuclear track detector (FNTD, the physical compartment), a device for individual particle detection and a substrate for viable cell-coating, i.e. the biological compartment. To date both compartments have been imaged sequentially in situ by confocal laser scanning microscopy (CLSM). This is yet in conflict with a functional read-out of the Cell-Fit-HD utilizing a fast live-cell imaging of the biological compartment with low phototoxicity on greater time scales. The read-out of the biological from the physical compartment was uncoupled. A read-out procedure was developed to image the cell layer by conventional widefield microscopy whereas the FNTD was imaged by CLSM. Point mapping registration of the confocal and widefield imaging data was performed. Non-fluorescent crystal defects (spinels) visible in both read-outs were used as control point pairs. The accuracy achieved was on the sub-µm scale. The read-out procedure by widefield microscopy does not impair the unique ability of spatial correlation by the Cell-Fit-HD. The uncoupling will enlarge the application potential of the hybrid technology significantly. The registration allows for an ultimate correlation of microscopic physical beam parameters and cell kinetics on greater time scales. The method reported herein will be instrumental for the introduction of a novel generation of compact detectors facilitating biodosimetric research towards high-throughput analysis. PMID:27499388

  2. Modified-live infectious bovine rhinotracheitis virus vaccine expressing monomer and dimer forms of foot-and-mouth disease capsid protein epitopes on surface of hybrid virus particles.

    PubMed

    Kit, S; Kit, M; DiMarchi, R D; Little, S P; Gale, C

    1991-01-01

    Modified-live, attenuated infectious bovine rhinotracheitis (IBR) hybrid virus vaccines have been constructed by inserting in the major IBRV glycoprotein gIII gene chemically synthesized deoxyribonucleotide sequences encoding the bovine growth hormone signal sequence and monomeric or dimeric forms of the foot and mouth disease virus (FMDV) VP 1 epitope sequences. The foreign DNA sequences were inserted at the N-terminal end of the IBRV gIII coding sequence and were driven by the IBRV gIII promoter. The sequences encoding the first 38 and the first 21 amino acids of the IBRV gIII were deleted from the hybrid viruses containing inserts of the monomeric and dimeric FMDV epitope sequences, respectively, to avoid redundant signal sequences. Plaque immunoassay experiments with guinea pig and bovine anti-FMDV peptide antisera, and with anti-IBRV gIII monoclonal antibodies demonstrated that IBRV-FMDV fusion proteins were expressed in virus-infected MDBK cells. Immunoelectron microscopy analyses demonstrated that the IBRV-FMDV fusion proteins were expressed as repeated structures on the surface of virus particles. Experiments showed that the recombinant IBRV-FMDV viruses protected cattle from IBRV (Cooper) challenge and induced anti-FMDV peptide antibodies, thereby demonstrating that the FMDV epitopes were expressed in vivo. PMID:1718244

  3. Particle-in-cell simulations of an alpha channeling scenario: electron current drive arising from lower hybrid drift instability of fusion-born ions

    NASA Astrophysics Data System (ADS)

    Cook, James; Chapman, Sandra; Dendy, Richard

    2010-11-01

    Particle-in-cell (PIC) simulations of fusion-born protons in deuterium plasmas demonstrate a key alpha channeling phenomenon for tokamak fusion plasmas. We focus on obliquely propagating modes at the plasma edge, excited by centrally born fusion products on banana orbits, known to be responsible for observations of ion cyclotron emission in JET and TFTR. A fully self-consistent electromagnetic 1D3V PIC code evolves a ring-beam distribution of 3MeV protons in a 10keV thermal deuterium-electron plasma with realistic mass ratio. A collective instability occurs, giving rise to electromagnetic field activity in the lower hybrid range of frequencies. Waves spontaneously excited by this lower hybrid drift instability undergo Landau damping on resonant electrons, drawing out an asymmetric tail in the distribution of electron parallel velocities, which constitutes a net current. These simulations demonstrate a key building block of some alpha channeling scenarios: the direct collisionless coupling of fusion product energy into a form which can help sustain the equilibrium of the tokamak.

  4. Discrete auroras and magnetotail processes.

    NASA Astrophysics Data System (ADS)

    Lyons, L. R.

    Important information about magnetospheric phenomena associated with auroras and substorms can be inferred from low-altitude auroral observations. Satellite observations have shown that discrete auroral arcs lie within a boundary plasma sheet (BPS) region that is outside the central plasma sheet (CPS). The observations imply that arcs are generated along BPS field lines by magnetospheric processes that form large, perpendicular electric field structures. The BPS and the arc generation processes apparently lie along field lines that are in the vicinity of the boundary between open and closed field lines and cross the tail (or magnetopause) current sheet. Ground-based observations show that the first indication of a substorm onset is the brightening of a quiet, discrete arc. This suggests that substorms are initiated along the BPS field lines associated with arc generation, and not within the CPS. Finally, auroral observations have shown that the area of open, polar-cap field lines varies considerably during periods of geomagnetic activity. Expansion of the polar cap has the potential for releasing trapped plasma sheet particles along freshly open field lines. The resulting evacuation of field lines has the potential for being an important loss process for the plasma sheet and for being a source of tailward flows and energetic particle bursts in the tail.

  5. Fluid-particle hybrid simulation on the transports of plasma, recycling neutrals, and carbon impurities in the Korea Superconducting Tokamak Advanced Research divertor region

    NASA Astrophysics Data System (ADS)

    Kim, Deok-Kyu; Hong, Sang Hee

    2005-06-01

    A two-dimensional simulation modeling that has been performed in a self-consistent way for analysis on the fully coupled transports of plasma, recycling neutrals, and intrinsic carbon impurities in the divertor domain of tokamaks is presented. The numerical model coupling the three major species transports in the tokamak edge is based on a fluid-particle hybrid approach where the plasma is described as a single magnetohydrodynamic fluid while the neutrals and impurities are treated as kinetic particles using the Monte Carlo technique. This simulation code is applied to the KSTAR (Korea Superconducting Tokamak Advanced Research) tokamak [G. S. Lee, J. Kim, S. M. Hwang et al., Nucl. Fusion 40, 575 (2000)] to calculate the peak heat flux on the divertor plate and to explore the divertor plasma behavior depending on the upstream conditions in its base line operation mode for various values of input heating power and separatrix plasma density. The numerical modeling for the KSTAR tokamak shows that its full-powered operation is subject to the peak heat loads on the divertor plate exceeding an engineering limit, and reveals that the recycling zone is formed in front of the divertor by increasing plasma density and by reducing power flow into the scrape-off layer. Compared with other researchers' work, the present hybrid simulation more rigorously reproduces severe electron pressure losses along field lines by the presence of recycling zone accounting for the transitions between the sheath limited and the detached divertor regimes. The substantial profile changes in carbon impurity population and ionic composition also represent the key features of this divertor regime transition.

  6. PREFACE: 4th Symposium on Prospects in the Physics of Discrete Symmetries (DISCRETE2014)

    NASA Astrophysics Data System (ADS)

    Di Domenico, Antonio; Mavromatos, Nick E.; Mitsou, Vasiliki A.; Skliros, Dimitri P.

    2015-07-01

    The DISCRETE 2014: Fourth Symposium in the Physics of Discrete Symmetries took place at King's College London, Strand Campus, London WC2R 2LS, from Tuesday, December 2 2014 till Saturday, December 6 2014. This is the fourth Edition of the DISCRETE conference series, which is a biannual event, having been held previously in Valencia (Discrete'08), Rome (Discrete2010) and Lisbon (Discrete2012). The topics covered at the DISCRETE series of conferences are: T, C, P, CP symmetries; accidental symmetries (B, L conservation); CPT symmetry, decoherence and entangled states, Lorentz symmetry breaking (phenomenology and current bounds); neutrino mass and mixing; implications for cosmology and astroparticle physics, dark matter searches; experimental prospects at LHC, new facilities. In DISCRETE 2014 we have also introduced two new topics: cosmological aspects of non-commutative space-times as well as PT symmetric Hamiltonians (non-Hermitian but with real eigenvalues), a topic that has wide applications in particle physics and beyond. The conference was opened by the King's College London Vice Principal on Research and Innovation, Mr Chris Mottershead, followed by a welcome address by the Chair of DISCRETE 2014 (Professor Nick E. Mavromatos). After these introductory talks, the scientific programme of the DISCRETE 2014 symposium started. Following the tradition of DISCRETE series of conferences, the talks (138 in total) were divided into plenary-review talks (25), invited research talks (50) and shorter presentations (63) — selected by the conveners of each session in consultation with the organisers — from the submitted abstracts. We have been fortunate to have very high-quality, thought stimulating and interesting talks at all levels, which, together with the discussions among the participants, made the conference quite enjoyable. There were 152 registered participants for the event.

  7. Discrete monotron oscillator

    SciTech Connect

    Carlsten, B.E.; Haynes, W.B.

    1996-08-01

    The authors theoretically and numerically investigate the operation and behavior of the discrete monotron oscillator, a novel high-power microwave source. The discrete monotron differs from conventional monotrons and transit time oscillators by shielding the electron beam from the monotron cavity`s RF fields except at two distinct locations. This makes the discrete monotron act more like a klystron than a distributed traveling wave device. As a result, the oscillator has higher efficiency and can operate with higher beam powers than other single cavity oscillators and has more stable operation without requiring a seed input signal than mildly relativistic, intense-beam klystron oscillators.

  8. The Discrete Hanging Cable

    ERIC Educational Resources Information Center

    Peters, James V.

    2004-01-01

    Using the methods of finite difference equations the discrete analogue of the parabolic and catenary cable are analysed. The fibonacci numbers and the golden ratio arise in the treatment of the catenary.

  9. A framework of fuzzy hybrid systems for modelling and control

    NASA Astrophysics Data System (ADS)

    Cheng, Shu; Dong, Ruijun; Pedrycz, Witold

    2010-02-01

    This paper presents a new approach to modelling and control of hybrid systems with both continuous variables and discrete events. Applying the fuzzy set theory, a hierarchical fuzzy hybrid structure consisting of a fuzzy discrete event dynamic system and a continuous variable dynamic system is constructed, which not only captures the hybrid continuous/discrete dynamics but also handles the uncertainties in states and state transitions. The identification of continuous and discrete components is developed, and the hybrid control is then synthesised by fuzzy IF-THEN rules embedded in the fuzzy interface. An example of the optimisation of a production line in manufacturing shows the efficacy of the proposed approach.

  10. Self-assembly of carbon nanotubes in polymer melts: simulation of structural and electrical behaviour by hybrid particle-field molecular dynamics.

    PubMed

    Zhao, Ying; Byshkin, Maksym; Cong, Yue; Kawakatsu, Toshihiro; Guadagno, Liberata; De Nicola, Antonio; Yu, Naisen; Milano, Giuseppe; Dong, Bin

    2016-08-25

    Self-assembly processes of carbon nanotubes (CNTs) dispersed in different polymer phases have been investigated using a hybrid particle-field molecular dynamics technique (MD-SCF). This efficient computational method allowed simulations of large-scale systems (up to ∼1 500 000 particles) of flexible rod-like particles in different matrices made of bead spring chains on the millisecond time scale. The equilibrium morphologies obtained for longer CNTs are in good agreement with those proposed by several experimental studies that hypothesized a two level "multiscale" organization of CNT assemblies. In addition, the electrical properties of the assembled structures have been calculated using a resistor network approach. The calculated behaviour of the conductivities for longer CNTs is consistent with the power laws obtained by numerous experiments. In particular, according to the interpretation established by the systematic studies of Bauhofer and Kovacs, systems close to "statistical percolation" show exponents t ∼ 2 for the power law dependence of the electrical conductivity on the CNT fraction, and systems in which the CNTs reach equilibrium aggregation show exponents t close to 1.7 ("kinetic percolation"). The confinement effects on the assembled structures and their corresponding conductivity behaviour in a non-homogeneous matrix, such as the phase separating block copolymer melt, have also been simulated using different starting configurations. The simulations reported herein contribute to a microscopic interpretation of the literature results, and the proposed modelling procedure may contribute meaningfully to the rational design of strategies aimed at optimizing nanomaterials for improved electrical properties.

  11. Self-assembly of carbon nanotubes in polymer melts: simulation of structural and electrical behaviour by hybrid particle-field molecular dynamics.

    PubMed

    Zhao, Ying; Byshkin, Maksym; Cong, Yue; Kawakatsu, Toshihiro; Guadagno, Liberata; De Nicola, Antonio; Yu, Naisen; Milano, Giuseppe; Dong, Bin

    2016-08-25

    Self-assembly processes of carbon nanotubes (CNTs) dispersed in different polymer phases have been investigated using a hybrid particle-field molecular dynamics technique (MD-SCF). This efficient computational method allowed simulations of large-scale systems (up to ∼1 500 000 particles) of flexible rod-like particles in different matrices made of bead spring chains on the millisecond time scale. The equilibrium morphologies obtained for longer CNTs are in good agreement with those proposed by several experimental studies that hypothesized a two level "multiscale" organization of CNT assemblies. In addition, the electrical properties of the assembled structures have been calculated using a resistor network approach. The calculated behaviour of the conductivities for longer CNTs is consistent with the power laws obtained by numerous experiments. In particular, according to the interpretation established by the systematic studies of Bauhofer and Kovacs, systems close to "statistical percolation" show exponents t ∼ 2 for the power law dependence of the electrical conductivity on the CNT fraction, and systems in which the CNTs reach equilibrium aggregation show exponents t close to 1.7 ("kinetic percolation"). The confinement effects on the assembled structures and their corresponding conductivity behaviour in a non-homogeneous matrix, such as the phase separating block copolymer melt, have also been simulated using different starting configurations. The simulations reported herein contribute to a microscopic interpretation of the literature results, and the proposed modelling procedure may contribute meaningfully to the rational design of strategies aimed at optimizing nanomaterials for improved electrical properties. PMID:27463779

  12. Mesoporous silica particle-PLA-PANI hybrid scaffolds for cell-directed intracellular drug delivery and tissue vascularization

    NASA Astrophysics Data System (ADS)

    Shokry, Hussein; Vanamo, Ulriika; Wiltschka, Oliver; Niinimäki, Jenni; Lerche, Martina; Levon, Kalle; Linden, Mika; Sahlgren, Cecilia

    2015-08-01

    Instructive materials are expected to revolutionize stem cell based tissue engineering. As many stem cell cues have adverse effects on normal tissue homeostasis, there is a need to develop bioactive scaffolds which offer locally retained and cell-targeted drug delivery for intracellular release in targeted cell populations. Further, the scaffolds need to support vascularization to promote tissue growth and function. We have developed an electrospun PLA-PANI fiber scaffold, and incorporated mesoporous silica nanoparticles within the scaffold matrix to obtain cell-targeted and localized drug delivery. The isotropy of the scaffold can be tuned to find the optimal morphology for a given application and the scaffold is electroactive to support differentiation of contractile tissues. We demonstrate that there is no premature drug release from particles under physiological conditions over a period of one week and that the drug is released upon internalization of particles by cells within the scaffold. The scaffold is biocompatible, supports muscle stem cell differentiation and cell-seeded scaffolds are vascularized in vivo upon transplantation on the chorioallantoic membrane of chicken embryos. The scaffold is a step towards instructive biomaterials for local control of stem cell differentiation, and tissue formation supported by vascularization and without adverse effects on the homeostasis of adjacent tissues due to diffusion of biological cues.Instructive materials are expected to revolutionize stem cell based tissue engineering. As many stem cell cues have adverse effects on normal tissue homeostasis, there is a need to develop bioactive scaffolds which offer locally retained and cell-targeted drug delivery for intracellular release in targeted cell populations. Further, the scaffolds need to support vascularization to promote tissue growth and function. We have developed an electrospun PLA-PANI fiber scaffold, and incorporated mesoporous silica nanoparticles within

  13. Single inclusive particle production in proton-nucleus collisions at next-to-leading order in the hybrid formalism

    NASA Astrophysics Data System (ADS)

    Altinoluk, Tolga; Armesto, Néstor; Beuf, Guillaume; Kovner, Alex; Lublinsky, Michael

    2015-05-01

    We reconsider the perturbative next-to-leading calculation of the single inclusive hadron production in the framework of the hybrid formalism, applied to hadron production in proton-nucleus collisions. Our analysis, performed in the wave function approach, differs from the previous works in three points. First, we are careful to specify unambiguously the rapidity interval that has to be included in the evolution of the leading-order eikonal scattering amplitude. This is important, since varying this interval by a number of order unity changes the next-to-leading order correction that the calculation is meant to determine. Second, we introduce the explicit requirement that fast fluctuations in the projectile wave function which only exist for a short time are not resolved by the target. This Ioffe time cutoff also strongly affects the next-to-leading order terms. Third, our result does not employ the approximation of a large number of colors. Our final expressions are unambiguous and do not coincide at next-to-leading order with the results available in the literature.

  14. Mesoporous silica particle-PLA-PANI hybrid scaffolds for cell-directed intracellular drug delivery and tissue vascularization.

    PubMed

    Shokry, Hussein; Vanamo, Ulriika; Wiltschka, Oliver; Niinimäki, Jenni; Lerche, Martina; Levon, Kalle; Linden, Mika; Sahlgren, Cecilia

    2015-09-14

    Instructive materials are expected to revolutionize stem cell based tissue engineering. As many stem cell cues have adverse effects on normal tissue homeostasis, there is a need to develop bioactive scaffolds which offer locally retained and cell-targeted drug delivery for intracellular release in targeted cell populations. Further, the scaffolds need to support vascularization to promote tissue growth and function. We have developed an electrospun PLA-PANI fiber scaffold, and incorporated mesoporous silica nanoparticles within the scaffold matrix to obtain cell-targeted and localized drug delivery. The isotropy of the scaffold can be tuned to find the optimal morphology for a given application and the scaffold is electroactive to support differentiation of contractile tissues. We demonstrate that there is no premature drug release from particles under physiological conditions over a period of one week and that the drug is released upon internalization of particles by cells within the scaffold. The scaffold is biocompatible, supports muscle stem cell differentiation and cell-seeded scaffolds are vascularized in vivo upon transplantation on the chorioallantoic membrane of chicken embryos. The scaffold is a step towards instructive biomaterials for local control of stem cell differentiation, and tissue formation supported by vascularization and without adverse effects on the homeostasis of adjacent tissues due to diffusion of biological cues. PMID:26252158

  15. Implicit and explicit schemes for mass consistency preservation in hybrid particle/finite-volume algorithms for turbulent reactive flows

    SciTech Connect

    Popov, Pavel P. Pope, Stephen B.

    2014-01-15

    This work addresses the issue of particle mass consistency in Large Eddy Simulation/Probability Density Function (LES/PDF) methods for turbulent reactive flows. Numerical schemes for the implicit and explicit enforcement of particle mass consistency (PMC) are introduced, and their performance is examined in a representative LES/PDF application, namely the Sandia–Sydney Bluff-Body flame HM1. A new combination of interpolation schemes for velocity and scalar fields is found to better satisfy PMC than multilinear and fourth-order Lagrangian interpolation. A second-order accurate time-stepping scheme for stochastic differential equations (SDE) is found to improve PMC relative to Euler time stepping, which is the first time that a second-order scheme is found to be beneficial, when compared to a first-order scheme, in an LES/PDF application. An explicit corrective velocity scheme for PMC enforcement is introduced, and its parameters optimized to enforce a specified PMC criterion with minimal corrective velocity magnitudes.

  16. Depression: discrete or continuous?

    PubMed

    Bowins, Brad

    2015-01-01

    Elucidating the true structure of depression is necessary if we are to advance our understanding and treatment options. Central to the issue of structure is whether depression represents discrete types or occurs on a continuum. Nature almost universally operates on the basis of continuums, whereas human perception favors discrete categories. This reality might be formalized into a 'continuum principle': natural phenomena tend to occur on a continuum, and any instance of hypothesized discreteness requires unassailable proof. Research evidence for discrete types falls far short of this standard, with most evidence supporting a continuum. However, quantitative variation can yield qualitative differences as an emergent property, fostering the appearance of discreteness. Depression as a continuum is best characterized by duration and severity dimensions, with the latter understood in terms of depressive inhibition. In the absence of some degree of cognitive, emotional, social, and physical inhibition, depression should not be diagnosed. Combining the dimensions of duration and severity provides an optimal way to characterize the quantitative and related qualitative aspects of depression and to describe the overall degree of dysfunction. The presence of other symptom types occurs when anxiety, hypomanic/manic, psychotic, and personality continuums interface with the depression continuum. PMID:25531962

  17. A hybrid approach for quantizing complicated motion of a charged particle in time-varying magnetic field

    SciTech Connect

    Menouar, Salah; Choi, Jeong Ryeol

    2015-02-15

    Quantum characteristics of a charged particle subjected to a singular oscillator potential under an external magnetic field is investigated via SU(1,1) Lie algebraic approach together with the invariant operator and the unitary transformation methods. The system we managed is somewhat complicated since we considered not only the time-variation of the effective mass of the system but also the dependence of the external magnetic field on time in an arbitrary fashion. In this case, the system is a kind of time-dependent Hamiltonian systems which require more delicate treatment when we study it. The complete wave functions are obtained without relying on the methods of perturbation and/or approximation, and the global phases of the system are identified. To promote the understanding of our development, we applied it to a particular case, assuming that the effective mass slowly varies with time under a time-dependent magnetic field.

  18. Discrete artificial bee colony algorithm for lot-streaming flowshop with total flowtime minimization

    NASA Astrophysics Data System (ADS)

    Sang, Hongyan; Gao, Liang; Pan, Quanke

    2012-09-01

    Unlike a traditional flowshop problem where a job is assumed to be indivisible, in the lot-streaming flowshop problem, a job is allowed to overlap its operations between successive machines by splitting it into a number of smaller sub-lots and moving the completed portion of the sub-lots to downstream machine. In this way, the production is accelerated. This paper presents a discrete artificial bee colony (DABC) algorithm for a lot-streaming flowshop scheduling problem with total flowtime criterion. Unlike the basic ABC algorithm, the proposed DABC algorithm represents a solution as a discrete job permutation. An efficient initialization scheme based on the extended Nawaz-Enscore-Ham heuristic is utilized to produce an initial population with a certain level of quality and diversity. Employed and onlooker bees generate new solutions in their neighborhood, whereas scout bees generate new solutions by performing insert operator and swap operator to the best solution found so far. Moreover, a simple but effective local search is embedded in the algorithm to enhance local exploitation capability. A comparative experiment is carried out with the existing discrete particle swarm optimization, hybrid genetic algorithm, threshold accepting, simulated annealing and ant colony optimization algorithms based on a total of 160 randomly generated instances. The experimental results show that the proposed DABC algorithm is quite effective for the lot-streaming flowshop with total flowtime criterion in terms of searching quality, robustness and effectiveness. This research provides the references to the optimization research on lot-streaming flowshop.

  19. Deformed discrete symmetries

    NASA Astrophysics Data System (ADS)

    Arzano, Michele; Kowalski-Glikman, Jerzy

    2016-09-01

    We construct discrete symmetry transformations for deformed relativistic kinematics based on group valued momenta. We focus on the specific example of κ-deformations of the Poincaré algebra with associated momenta living on (a sub-manifold of) de Sitter space. Our approach relies on the description of quantum states constructed from deformed kinematics and the observable charges associated with them. The results we present provide the first step towards the analysis of experimental bounds on the deformation parameter κ to be derived via precision measurements of discrete symmetries and CPT.

  20. Discrete breathers in crystals

    NASA Astrophysics Data System (ADS)

    Dmitriev, S. V.; Korznikova, E. A.; Baimova, Yu A.; Velarde, M. G.

    2016-05-01

    It is well known that periodic discrete defect-containing systems, in addition to traveling waves, support vibrational defect-localized modes. It turned out that if a periodic discrete system is nonlinear, it can support spatially localized vibrational modes as exact solutions even in the absence of defects. Since the nodes of the system are all on equal footing, it is only through the special choice of initial conditions that a group of nodes can be found on which such a mode, called a discrete breather (DB), will be excited. The DB frequency must be outside the frequency range of the small-amplitude traveling waves. Not resonating with and expending no energy on the excitation of traveling waves, a DB can theoretically conserve its vibrational energy forever provided no thermal vibrations or other perturbations are present. Crystals are nonlinear discrete systems, and the discovery in them of DBs was only a matter of time. It is well known that periodic discrete defect-containing systems support both traveling waves and vibrational defect-localized modes. It turns out that if a periodic discrete system is nonlinear, it can support spatially localized vibrational modes as exact solutions even in the absence of defects. Because the nodes of the system are all on equal footing, only a special choice of the initial conditions allows selecting a group of nodes on which such a mode, called a discrete breather (DB), can be excited. The DB frequency must be outside the frequency range of small-amplitude traveling waves. Not resonating with and expending no energy on the excitation of traveling waves, a DB can theoretically preserve its vibrational energy forever if no thermal vibrations or other perturbations are present. Crystals are nonlinear discrete systems, and the discovery of DBs in them was only a matter of time. Experimental studies of DBs encounter major technical difficulties, leaving atomistic computer simulations as the primary investigation tool. Despite

  1. Specific volume coupling and convergence properties in hybrid particle/finite volume algorithms for turbulent reactive flows

    NASA Astrophysics Data System (ADS)

    Popov, Pavel P.; Wang, Haifeng; Pope, Stephen B.

    2015-08-01

    We investigate the coupling between the two components of a Large Eddy Simulation/Probability Density Function (LES/PDF) algorithm for the simulation of turbulent reacting flows. In such an algorithm, the Large Eddy Simulation (LES) component provides a solution to the hydrodynamic equations, whereas the Lagrangian Monte Carlo Probability Density Function (PDF) component solves for the PDF of chemical compositions. Special attention is paid to the transfer of specific volume information from the PDF to the LES code: the specific volume field contains probabilistic noise due to the nature of the Monte Carlo PDF solution, and thus the use of the specific volume field in the LES pressure solver needs careful treatment. Using a test flow based on the Sandia/Sydney Bluff Body Flame, we determine the optimal strategy for specific volume feedback. Then, the overall second-order convergence of the entire LES/PDF procedure is verified using a simple vortex ring test case, with special attention being given to bias errors due to the number of particles per LES Finite Volume (FV) cell.

  2. Fast Mix Table Construction for Material Discretization

    SciTech Connect

    Johnson, Seth R

    2013-01-01

    An effective hybrid Monte Carlo--deterministic implementation typically requires the approximation of a continuous geometry description with a discretized piecewise-constant material field. The inherent geometry discretization error can be reduced somewhat by using material mixing, where multiple materials inside a discrete mesh voxel are homogenized. Material mixing requires the construction of a ``mix table,'' which stores the volume fractions in every mixture so that multiple voxels with similar compositions can reference the same mixture. Mix table construction is a potentially expensive serial operation for large problems with many materials and voxels. We formulate an efficient algorithm to construct a sparse mix table in $O(\\text{number of voxels}\\times \\log \\text{number of mixtures})$ time. The new algorithm is implemented in ADVANTG and used to discretize continuous geometries onto a structured Cartesian grid. When applied to an end-of-life MCNP model of the High Flux Isotope Reactor with 270 distinct materials, the new method improves the material mixing time by a factor of 100 compared to a naive mix table implementation.

  3. What Is Discrete Mathematics?

    ERIC Educational Resources Information Center

    Sharp, Karen Tobey

    This paper cites information received from a number of sources, e.g., mathematics teachers in two-year colleges, publishers, and convention speakers, about the nature of discrete mathematics and about what topics a course in this subject should contain. Note is taken of the book edited by Ralston and Young which discusses the future of college…

  4. Discrete cavity solitons.

    PubMed

    Peschel, U; Egorov, O; Lederer, F

    2004-08-15

    We derive evolution equations describing light propagation in an array of coupled-waveguide resonators and predict the existence of discrete cavity solitons. We identify stable, unstable, and oscillating solitons by varying the coupling strength between the anticontinuous and the continuous limit. PMID:15357356

  5. DOS: the discrete-ordinates system. [LMFBR

    SciTech Connect

    Rhoades, W. A.; Emmett, M. B.

    1982-09-01

    The Discrete Ordinates System determines the flux of neutrons or photons due either to fixed sources specified by the user or to sources generated by particle interaction with the problem materials. It also determines numerous secondary results which depend upon flux. Criticality searches can be performed. Numerous input, output, and file manipulation facilities are provided. The DOS driver program reads the problem specification from an input file and calls various program modules into execution as specified by the input file.

  6. Numerical Simulation of 3D particulate flow by Coupling Multi-Fluid Model with Discrete Element Method

    NASA Astrophysics Data System (ADS)

    Guo, Liancheng; Morita, Koji; Tagami, Hirotaka; Tobita, Yoshiharu

    2014-06-01

    The postulated core disruptive accidents (CDAs) are regarded as particular difficulties in the safety analysis of liquid-metal fast reactors (LMFRs). In CDAs, the motions and interactions of solid particles, such as refrozen fuels, disrupted pellets, etc., not only dominate fundamental behaviors of multiphase flows, but also drastically influence the process of CDAs. The fast reactor safety analysis code, SIMMER-IV, which is a 3D, multi-velocity-field, multiphase, multicomponent, Eulerian, fluid dynamics code coupled with a fuel-pin model and a space- and energy-dependent neutron kinetics model, was successfully applied to a series of CDA assessments. However, strong interactions among solid particles as well as particle characteristics in multiphase flows with rich solid particles were not taken into consideration for fluid-dynamics models of SIMMER-IV. In this article, a hybrid method for multiphase flow analysis is developed by coupling the discrete element method (DEM) with the multi-fluid model of SIMMER-IV. In the coupling algorithm, motions of liquid and gas phases are solved by a time-factorization (time-splitting) method. For the solid phases, contacts among particles and interactions with fluid phases are considered through DEM. Numerical simulations of dam-break behavior with rich solid particles show reasonable agreements with corresponding experimental results. It is expected that SIMMER-IV coupled with DEM could provide a promising and useful computational tool for complicated multiphase-flow phenomena with high concentration of solid particles.

  7. Structure and weights optimisation of a modified Elman network emotion classifier using hybrid computational intelligence algorithms: a comparative study

    NASA Astrophysics Data System (ADS)

    Sheikhan, Mansour; Abbasnezhad Arabi, Mahdi; Gharavian, Davood

    2015-10-01

    Artificial neural networks are efficient models in pattern recognition applications, but their performance is dependent on employing suitable structure and connection weights. This study used a hybrid method for obtaining the optimal weight set and architecture of a recurrent neural emotion classifier based on gravitational search algorithm (GSA) and its binary version (BGSA), respectively. By considering the features of speech signal that were related to prosody, voice quality, and spectrum, a rich feature set was constructed. To select more efficient features, a fast feature selection method was employed. The performance of the proposed hybrid GSA-BGSA method was compared with similar hybrid methods based on particle swarm optimisation (PSO) algorithm and its binary version, PSO and discrete firefly algorithm, and hybrid of error back-propagation and genetic algorithm that were used for optimisation. Experimental tests on Berlin emotional database demonstrated the superior performance of the proposed method using a lighter network structure.

  8. Discreteness induced extinction

    NASA Astrophysics Data System (ADS)

    dos Santos, Renato Vieira; da Silva, Linaena Méricy

    2015-11-01

    Two simple models based on ecological problems are discussed from the point of view of non-equilibrium statistical mechanics. It is shown how discrepant may be the results of the models that include spatial distribution with discrete interactions when compared with the continuous analogous models. In the continuous case we have, under certain circumstances, the population explosion. When we take into account the finiteness of the population, we get the opposite result, extinction. We will analyze how these results depend on the dimension d of the space and describe the phenomenon of the "Discreteness Inducing Extinction" (DIE). The results are interpreted in the context of the "paradox of sex", an old problem of evolutionary biology.

  9. Fluctuations and discreteness in diffusion limited growth

    NASA Astrophysics Data System (ADS)

    Devita, Jason P.

    This thesis explores the effects of fluctuations and discreteness on the growth of physical systems where diffusion plays an important role. It focuses on three related problems, all dependent on diffusion in a fundamental way, but each with its own unique challenges. With diffusion-limited aggregation (DLA), the relationship between noisy and noise-free Laplacian growth is probed by averaging the results of noisy growth. By doing so in a channel geometry, we are able to compare to known solutions of the noise-free problem. We see that while the two are comparable, there are discrepancies which are not well understood. In molecular beam epitaxy (MBE), we create efficient computational algorithms, by replacing random walkers (diffusing atoms) with approximately equivalent processes. In one case, the atoms are replaced by a continuum field. Solving for the dynamics of the field yields---in an average sense---the dynamics of the atoms. In the other case, the atoms are treated as individual random-walking particles, but the details of the dynamics are changed to an (approximately) equivalent set of dynamics. This approach involves allowing adatoms to take long hops. We see approximately an order of magnitude speed up for simulating island dynamics, mound growth, and Ostwald ripening. Some ideas from the study of MBE are carried over to the study of front propagation in reaction-diffusion systems. Many of the analytic results about front propagation are derived from continuum models. It is unclear, however, that these results accurately describe the properties of a discrete system. It is reasonable to think that discrete systems will converge to the continuum results when sufficiently many particles are included. However, computational evidence of this is difficult to obtain, since the interesting properties tend to depend on a power law of the logarithm of the number of particles. Thus, the number of particles included in simulations must be exceedingly large. By

  10. A paradigm for discrete physics

    SciTech Connect

    Noyes, H.P.; McGoveran, D.; Etter, T.; Manthey, M.J.; Gefwert, C.

    1987-01-01

    An example is outlined for constructing a discrete physics using as a starting point the insight from quantum physics that events are discrete, indivisible and non-local. Initial postulates are finiteness, discreteness, finite computability, absolute nonuniqueness (i.e., homogeneity in the absence of specific cause) and additivity.

  11. Efficient modal-expansion discrete-dipole approximation: Application to the simulation of optical extinction and electron energy-loss spectroscopies

    NASA Astrophysics Data System (ADS)

    Guillaume, Stéphane-Olivier; de Abajo, F. Javier García; Henrard, Luc

    2013-12-01

    An efficient procedure is introduced for the calculation of the optical response of individual and coupled metallic nanoparticles in the framework of the discrete-dipole approximation (DDA). We introduce a modal expansion in the basis set of discrete dipoles and show that a few suitably selected modes are sufficient to compute optical spectra with reasonable accuracy, thus reducing the required numerical effort relative to other DDA approaches. Our method offers a natural framework for the study of localized plasmon modes, including plasmon hybridization. As a proof of concept, we investigate optical extinction and electron energy-loss spectra of monomers, dimers, and quadrumers formed by flat silver squares. This method should find application to the previously prohibited simulation of complex particle arrays.

  12. Quantum cosmology based on discrete Feynman paths

    SciTech Connect

    Chew, Geoffrey F.

    2002-10-10

    Although the rules for interpreting local quantum theory imply discretization of process, Lorentz covariance is usually regarded as precluding time quantization. Nevertheless a time-discretized quantum representation of redshifting spatially-homogeneous universe may be based on discrete-step Feynman paths carrying causal Lorentz-invariant action--paths that not only propagate the wave function but provide a phenomenologically-promising elementary-particle Hilbert-space basis. In a model under development, local path steps are at Planck scale while, at a much larger ''wave-function scale'', global steps separate successive wave-functions. Wave-function spacetime is but a tiny fraction of path spacetime. Electromagnetic and gravitational actions are ''at a distance'' in Wheeler-Feynman sense while strong (color) and weak (isospin) actions, as well as action of particle motion, are ''local'' in a sense paralleling the action of local field theory. ''Nonmaterial'' path segments and ''trivial events'' collaborate to define energy and gravity. Photons coupled to conserved electric charge enjoy privileged model status among elementary fermions and vector bosons. Although real path parameters provide no immediate meaning for ''measurement'', the phase of the complex wave function allows significance for ''information'' accumulated through ''gentle'' electromagnetic events involving charged matter and ''soft'' photons. Through its soft-photon content the wave function is an ''information reservoir''.

  13. Discrete Dynamics Lab

    NASA Astrophysics Data System (ADS)

    Wuensche, Andrew

    DDLab is interactive graphics software for creating, visualizing, and analyzing many aspects of Cellular Automata, Random Boolean Networks, and Discrete Dynamical Networks in general and studying their behavior, both from the time-series perspective — space-time patterns, and from the state-space perspective — attractor basins. DDLab is relevant to research, applications, and education in the fields of complexity, self-organization, emergent phenomena, chaos, collision-based computing, neural networks, content addressable memory, genetic regulatory networks, dynamical encryption, generative art and music, and the study of the abstract mathematical/physical/dynamical phenomena in their own right.

  14. Ion conics and counterstreaming electrons generated by lower hybrid waves in the earth's magnetosphere

    NASA Technical Reports Server (NTRS)

    Chang, Tom; Crew, Geoffrey B.; Retterrer, John M.; Jasperse, John R.

    1989-01-01

    The exotic phenomenon of energetic ion-conic and counterstreaming electron formation by lower hybrid waves along discrete auroral field lines in the earth magnetosphere is considered. Mean-particle calculations, plasma simulations, and analytical treatments of the acceleration processes are described. It is shown that, in the primary auroral electron-beam region, lower hybrid waves could be an efficient mechanism for the transverse heating of H (+) and O(+) ions of ionospheric origin, as well as for the field-aligned heating of the ambient electrons leading to coincident counterstreaming electron distributions. For O(+) ions to be energized by such a wave-particle interaction process, however, some sort of preheating mechanism is required.

  15. Discrete-Time Goldfishing

    NASA Astrophysics Data System (ADS)

    Calogero, Francesco

    2011-08-01

    The original continuous-time ''goldfish'' dynamical system is characterized by two neat formulas, the first of which provides the N Newtonian equations of motion of this dynamical system, while the second provides the solution of the corresponding initial-value problem. Several other, more general, solvable dynamical systems ''of goldfish type'' have been identified over time, featuring, in the right-hand (''forces'') side of their Newtonian equations of motion, in addition to other contributions, a velocity-dependent term such as that appearing in the right-hand side of the first formula mentioned above. The solvable character of these models allows detailed analyses of their behavior, which in some cases is quite remarkable (for instance isochronous or asymptotically isochronous). In this paper we introduce and discuss various discrete-time dynamical systems, which are as well solvable, which also display interesting behaviors (including isochrony and asymptotic isochrony) and which reduce to dynamical systems of goldfish type in the limit when the discrete-time independent variable l=0,1,2,... becomes the standard continuous-time independent variable t, 0≤t<∞.

  16. Applied estimation for hybrid dynamical systems using perceptional information

    NASA Astrophysics Data System (ADS)

    Plotnik, Aaron M.

    This dissertation uses the motivating example of robotic tracking of mobile deep ocean animals to present innovations in robotic perception and estimation for hybrid dynamical systems. An approach to estimation for hybrid systems is presented that utilizes uncertain perceptional information about the system's mode to improve tracking of its mode and continuous states. This results in significant improvements in situations where previously reported methods of estimation for hybrid systems perform poorly due to poor distinguishability of the modes. The specific application that motivates this research is an automatic underwater robotic observation system that follows and films individual deep ocean animals. A first version of such a system has been developed jointly by the Stanford Aerospace Robotics Laboratory and Monterey Bay Aquarium Research Institute (MBARI). This robotic observation system is successfully fielded on MBARI's ROVs, but agile specimens often evade the system. When a human ROV pilot performs this task, one advantage that he has over the robotic observation system in these situations is the ability to use visual perceptional information about the target, immediately recognizing any changes in the specimen's behavior mode. With the approach of the human pilot in mind, a new version of the robotic observation system is proposed which is extended to (a) derive perceptional information (visual cues) about the behavior mode of the tracked specimen, and (b) merge this dissimilar, discrete and uncertain information with more traditional continuous noisy sensor data by extending existing algorithms for hybrid estimation. These performance enhancements are enabled by integrating techniques in hybrid estimation, computer vision and machine learning. First, real-time computer vision and classification algorithms extract a visual observation of the target's behavior mode. Existing hybrid estimation algorithms are extended to admit this uncertain but discrete

  17. Particle Swarm Optimization

    NASA Technical Reports Server (NTRS)

    Venter, Gerhard; Sobieszczanski-Sobieski Jaroslaw

    2002-01-01

    The purpose of this paper is to show how the search algorithm known as particle swarm optimization performs. Here, particle swarm optimization is applied to structural design problems, but the method has a much wider range of possible applications. The paper's new contributions are improvements to the particle swarm optimization algorithm and conclusions and recommendations as to the utility of the algorithm, Results of numerical experiments for both continuous and discrete applications are presented in the paper. The results indicate that the particle swarm optimization algorithm does locate the constrained minimum design in continuous applications with very good precision, albeit at a much higher computational cost than that of a typical gradient based optimizer. However, the true potential of particle swarm optimization is primarily in applications with discrete and/or discontinuous functions and variables. Additionally, particle swarm optimization has the potential of efficient computation with very large numbers of concurrently operating processors.

  18. Discrete Abelian gauge symmetries and axions

    NASA Astrophysics Data System (ADS)

    Honecker, Gabriele; Staessens, Wieland

    2015-07-01

    We combine two popular extensions of beyond the Standard Model physics within the framework of intersecting D6-brane models: discrete ℤn symmetries and Peccei-Quinn axions. The underlying natural connection between both extensions is formed by the presence of massive U(1) gauge symmetries in D-brane model building. Global intersecting D6-brane models on toroidal orbifolds of the type T6/ℤ2N and T6/ℤ2 × ℤ2M with discrete torsion offer excellent playgrounds for realizing these extensions. A generation-dependent ℤ2 symmetry is identified in a global Pati-Salam model, while global left-right symmetric models give rise to supersymmetric realizations of the DFSZ axion model. In one class of the latter models, the axion as well as Standard Model particles carry a non-trivial ℤ3 charge.

  19. Evaluating the Pedagogical Potential of Hybrid Models

    ERIC Educational Resources Information Center

    Levin, Tzur; Levin, Ilya

    2013-01-01

    The paper examines how the use of hybrid models--that consist of the interacting continuous and discrete processes--may assist in teaching system thinking. We report an experiment in which undergraduate students were asked to choose between a hybrid and a continuous solution for a number of control problems. A correlation has been found between…

  20. Approximate Schur complement preconditioning of the lowest order nodal discretizations

    SciTech Connect

    Moulton, J.D.; Ascher, U.M.; Morel, J.E.

    1996-12-31

    Particular classes of nodal methods and mixed hybrid finite element methods lead to equivalent, robust and accurate discretizations of 2nd order elliptic PDEs. However, widespread popularity of these discretizations has been hindered by the awkward linear systems which result. The present work exploits this awkwardness, which provides a natural partitioning of the linear system, by defining two optimal preconditioners based on approximate Schur complements. Central to the optimal performance of these preconditioners is their sparsity structure which is compatible with Dendy`s black box multigrid code.

  1. Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions

    DOEpatents

    Beattie, Kenneth L.

    1998-01-01

    An improved microfabricated apparatus for conducting a multiplicity of individual and simultaneous binding reactions is described. The apparatus comprises a substrate on which are located discrete and isolated sites for binding reactions. The apparatus is characterized by discrete and isolated regions that extend through said substrate and terminate on a second surface thereof such that when a test sample is allowed to the substrate, it is capable of penetrating through each such region during the course of said binding reaction. The apparatus is especially useful for sequencing by hybridization of DNA molecules.

  2. First-principles modeling of electromagnetic scattering by discrete and discretely heterogeneous random media

    NASA Astrophysics Data System (ADS)

    Mishchenko, Michael I.; Dlugach, Janna M.; Yurkin, Maxim A.; Bi, Lei; Cairns, Brian; Liu, Li; Panetta, R. Lee; Travis, Larry D.; Yang, Ping; Zakharova, Nadezhda T.

    2016-05-01

    A discrete random medium is an object in the form of a finite volume of a vacuum or a homogeneous material medium filled with quasi-randomly and quasi-uniformly distributed discrete macroscopic impurities called small particles. Such objects are ubiquitous in natural and artificial environments. They are often characterized by analyzing theoretically the results of laboratory, in situ, or remote-sensing measurements of the scattering of light and other electromagnetic radiation. Electromagnetic scattering and absorption by particles can also affect the energy budget of a discrete random medium and hence various ambient physical and chemical processes. In either case electromagnetic scattering must be modeled in terms of appropriate optical observables, i.e., quadratic or bilinear forms in the field that quantify the reading of a relevant optical instrument or the electromagnetic energy budget. It is generally believed that time-harmonic Maxwell's equations can accurately describe elastic electromagnetic scattering by macroscopic particulate media that change in time much more slowly than the incident electromagnetic field. However, direct solutions of these equations for discrete random media had been impracticable until quite recently. This has led to a widespread use of various phenomenological approaches in situations when their very applicability can be questioned. Recently, however, a new branch of physical optics has emerged wherein electromagnetic scattering by discrete and discretely heterogeneous random media is modeled directly by using analytical or numerically exact computer solutions of the Maxwell equations. Therefore, the main objective of this Report is to formulate the general theoretical framework of electromagnetic scattering by discrete random media rooted in the Maxwell-Lorentz electromagnetics and discuss its immediate analytical and numerical consequences. Starting from the microscopic Maxwell-Lorentz equations, we trace the development of

  3. Discrete Newtonian cosmology

    NASA Astrophysics Data System (ADS)

    Ellis, George F. R.; Gibbons, Gary W.

    2014-01-01

    In this paper we lay down the foundations for a purely Newtonian theory of cosmology, valid at scales small compared with the Hubble radius, using only Newtonian point particles acted on by gravity and a possible cosmological term. We describe the cosmological background which is given by an exact solution of the equations of motion in which the particles expand homothetically with their comoving positions constituting a central configuration. We point out, using previous work, that an important class of central configurations are homogeneous and isotropic, thus justifying the usual assumptions of elementary treatments. The scale factor is shown to satisfy the standard Raychaudhuri and Friedmann equations without making any fluid dynamic or continuum approximations. Since we make no commitment as to the identity of the point particles, our results are valid for cold dark matter, galaxies, or clusters of galaxies. In future publications we plan to discuss perturbations of our cosmological background from the point particle viewpoint laid down in this paper and show consistency with much standard theory usually obtained by more complicated and conceptually less clear continuum methods. Apart from its potential use in large scale structure studies, we believe that our approach has great pedagogic advantages over existing elementary treatments of the expanding universe, since it requires no use of general relativity or continuum mechanics but concentrates on the basic physics: Newton’s laws for gravitationally interacting particles.

  4. Integrable discrete PT symmetric model.

    PubMed

    Ablowitz, Mark J; Musslimani, Ziad H

    2014-09-01

    An exactly solvable discrete PT invariant nonlinear Schrödinger-like model is introduced. It is an integrable Hamiltonian system that exhibits a nontrivial nonlinear PT symmetry. A discrete one-soliton solution is constructed using a left-right Riemann-Hilbert formulation. It is shown that this pure soliton exhibits unique features such as power oscillations and singularity formation. The proposed model can be viewed as a discretization of a recently obtained integrable nonlocal nonlinear Schrödinger equation.

  5. Nonintegrable Schrodinger discrete breathers.

    PubMed

    Gómez-Gardeñes, J; Floría, L M; Peyrard, M; Bishop, A R

    2004-12-01

    In an extensive numerical investigation of nonintegrable translational motion of discrete breathers in nonlinear Schrödinger lattices, we have used a regularized Newton algorithm to continue these solutions from the limit of the integrable Ablowitz-Ladik lattice. These solutions are shown to be a superposition of a localized moving core and an excited extended state (background) to which the localized moving pulse is spatially asymptotic. The background is a linear combination of small amplitude nonlinear resonant plane waves and it plays an essential role in the energy balance governing the translational motion of the localized core. Perturbative collective variable theory predictions are critically analyzed in the light of the numerical results.

  6. Discrete bisoliton fiber laser

    PubMed Central

    Liu, X. M.; Han, X. X.; Yao, X. K.

    2016-01-01

    Dissipative solitons, which result from the intricate balance between dispersion and nonlinearity as well as gain and loss, are of the fundamental scientific interest and numerous important applications. Here, we report a fiber laser that generates bisoliton – two consecutive dissipative solitons that preserve a fixed separation between them. Deviations from this separation result in its restoration. It is also found that these bisolitons have multiple discrete equilibrium distances with the quantized separations, as is confirmed by the theoretical analysis and the experimental observations. The main feature of our laser is the anomalous dispersion that is increased by an order of magnitude in comparison to previous studies. Then the spectral filtering effect plays a significant role in pulse-shaping. The proposed laser has the potential applications in optical communications and high-resolution optics for coding and transmission of information in higher-level modulation formats. PMID:27767075

  7. Discrete Minimal Surface Algebras

    NASA Astrophysics Data System (ADS)

    Arnlind, Joakim; Hoppe, Jens

    2010-05-01

    We consider discrete minimal surface algebras (DMSA) as generalized noncommutative analogues of minimal surfaces in higher dimensional spheres. These algebras appear naturally in membrane theory, where sequences of their representations are used as a regularization. After showing that the defining relations of the algebra are consistent, and that one can compute a basis of the enveloping algebra, we give several explicit examples of DMSAs in terms of subsets of sln (any semi-simple Lie algebra providing a trivial example by itself). A special class of DMSAs are Yang-Mills algebras. The representation graph is introduced to study representations of DMSAs of dimension d ≤ 4, and properties of representations are related to properties of graphs. The representation graph of a tensor product is (generically) the Cartesian product of the corresponding graphs. We provide explicit examples of irreducible representations and, for coinciding eigenvalues, classify all the unitary representations of the corresponding algebras.

  8. Discrete Pearson distributions

    SciTech Connect

    Bowman, K.O. ); Shenton, L.R. ); Kastenbaum, M.A. , Basye, VA )

    1991-11-01

    These distributions are generated by a first order recursive scheme which equates the ratio of successive probabilities to the ratio of two corresponding quadratics. The use of a linearized form of this model will produce equations in the unknowns matched by an appropriate set of moments (assumed to exist). Given the moments we may find valid solutions. These are two cases; (1) distributions defined on the non-negative integers (finite or infinite) and (2) distributions defined on negative integers as well. For (1), given the first four moments, it is possible to set this up as equations of finite or infinite degree in the probability of a zero occurrence, the sth component being a product of s ratios of linear forms in this probability in general. For (2) the equation for the zero probability is purely linear but may involve slowly converging series; here a particular case is the discrete normal. Regions of validity are being studied. 11 refs.

  9. Distributed mean curvature on a discrete manifold for Regge calculus

    NASA Astrophysics Data System (ADS)

    Conboye, Rory; Miller, Warner A.; Ray, Shannon

    2015-09-01

    The integrated mean curvature of a simplicial manifold is well understood in both Regge Calculus and Discrete Differential Geometry. However, a well motivated pointwise definition of curvature requires a careful choice of the volume over which to uniformly distribute the local integrated curvature. We show that hybrid cells formed using both the simplicial lattice and its circumcentric dual emerge as a remarkably natural structure for the distribution of this local integrated curvature. These hybrid cells form a complete tessellation of the simplicial manifold, contain a geometric orthonormal basis, and are also shown to give a pointwise mean curvature with a natural interpretation as the fractional rate of change of the normal vector.

  10. Discrete Mathematics and Its Applications

    ERIC Educational Resources Information Center

    Oxley, Alan

    2010-01-01

    The article gives ideas that lecturers of undergraduate Discrete Mathematics courses can use in order to make the subject more interesting for students and encourage them to undertake further studies in the subject. It is possible to teach Discrete Mathematics with little or no reference to computing. However, students are more likely to be…

  11. Tracking colloid transport in porous media using discrete flow fields and sensitivity of simulated colloid deposition to space discretization.

    PubMed

    Li, Zhelong; Zhang, Dongxiao; Li, Xiqing

    2010-02-15

    Advances in pore structure characterization and lattice-Boltzmann (LB) simulations of flow fields in pore spaces are making mechanistic simulations of colloid transport in real porous media a realistic goal. The primary challenge to reach this goal may be the computational demand of LB flow simulations in discretized porous medium domains at an assemblage scale. In this work, flow fields in simple cubic and dense packing systems were simulated at different discretization resolutions using the LB method. The simulated flow fields were incorporated into to a three-dimensional particle tracking model to simulate colloid transport in the two systems. The simulated colloid deposition tended to become asymptotic at a critical discretization resolution (voxel-grain size ratio = 0.01) at groundwater flow regimes for colloids down to submicrometer level under favorable conditions and down to around 1 microm under unfavorable conditions. The average simulated fluid velocities near grain surfaces were extracted to explain the sensitivities of simulated depositions to space discretization under both conditions. At the critical discretization resolution, current computation capacity would allow flow simulations and particle tracking in assemblage porous medium domains. In addition, particle tracking simulations revealed that colloids may be retained in flow vortices under conditions both favorable and unfavorable for deposition. Colloid retention in flow vortices has been proposed only very recently. Here we provide a mechanistic confirmation to this novel retention process. PMID:20088544

  12. Discrete subaortic stenosis.

    PubMed Central

    Khan, M M; Varma, M P; Cleland, J; O'Kane, H O; Webb, S W; Mulholland, H C; Adgey, A A

    1981-01-01

    Data concerning 17 consecutive patients with discrete subaortic stenosis are recorded. Twelve patients underwent operative resection of the obstructing lesion. Of these all except one were symptomatic and all had electrocardiographic evidence of left ventricular hypertrophy or left ventricular hypertrophy with strain. They had a peak resting systolic left ventricular outflow tract gradient of greater than 50 mmHg as predicted from the combined cuff measurement of systolic blood pressure and the echocardiographically estimated left ventricular systolic pressure and/or as determined by cardiac catheterisation. The outflow tract gradient as predicted from M-mode echocardiography and peak systolic pressure showed close correlation with that measured at cardiac catheterisation or operation. During the postoperative follow-up from one month to 11 years, of 11 patients, one patient required a further operation for recurrence of the obstruction four years after the initial operation. All patients are now asymptomatic. Five patients have not had an operation. The left ventricular outflow tract gradient as assessed at the time of cardiac catheterisation was greater than 50 mmHg. One patient has been lost to follow-up. The remaining four have been followed from four to eight years and have remained asymptomatic and the electrocardiograms have remained unchanged. Careful follow-up of all patients is essential with continuing clinical assessment, electrocardiograms, M-mode and two-dimensional echocardiograms, and if necessary cardiac catheterisation. Prophylaxis against bacterial endocarditis is also essential. Images PMID:6457617

  13. Discreteness inducing coexistence

    NASA Astrophysics Data System (ADS)

    dos Santos, Renato Vieira

    2013-12-01

    Consider two species that diffuse through space. Consider further that they differ only in initial densities and, possibly, in diffusion constants. Otherwise they are identical. What happens if they compete with each other in the same environment? What is the influence of the discrete nature of the interactions on the final destination? And what are the influence of diffusion and additive fluctuations corresponding to random migration and immigration of individuals? This paper aims to answer these questions for a particular competition model that incorporates intra and interspecific competition between the species. Based on mean field theory, the model has a stationary state dependent on the initial density conditions. We investigate how this initial density dependence is affected by the presence of demographic multiplicative noise and additive noise in space and time. There are three main conclusions: (1) Additive noise favors denser populations at the expense of the less dense, ratifying the competitive exclusion principle. (2) Demographic noise, on the other hand, favors less dense populations at the expense of the denser ones, inducing equal densities at the quasi-stationary state, violating the aforementioned principle. (3) The slower species always suffers the more deleterious effects of statistical fluctuations in a homogeneous medium.

  14. Entanglement swapping between discrete and continuous variables.

    PubMed

    Takeda, Shuntaro; Fuwa, Maria; van Loock, Peter; Furusawa, Akira

    2015-03-13

    We experimentally realize "hybrid" entanglement swapping between discrete-variable (DV) and continuous-variable (CV) optical systems. DV two-mode entanglement as obtainable from a single photon split at a beam splitter is robustly transferred by means of efficient CV entanglement and operations, using sources of squeezed light and homodyne detections. The DV entanglement after the swapping is verified without postselection by the logarithmic negativity of up to 0.28±0.01. Furthermore, our analysis shows that the optimally transferred state can be postselected into a highly entangled state that violates a Clauser-Horne-Shimony-Holt inequality by more than 4 standard deviations, and thus it may serve as a resource for quantum teleportation and quantum cryptography. PMID:25815914

  15. Discrete Glimpses of the Physics Landscape after the Higgs Discovery

    NASA Astrophysics Data System (ADS)

    Ellis, John

    2015-07-01

    What is the Higgs boson telling us? What else is there? How do we find it? This talk discusses these current topics in particle physics in the wake of the Higgs discovery, with particular emphasis on the discrete symmetries CP and R-parity, not forgetting flavour physics and dark matter, and finishing with some remarks about possible future colliders.

  16. Absorption properties of metal-semiconductor hybrid nanoparticles.

    PubMed

    Shaviv, Ehud; Schubert, Olaf; Alves-Santos, Marcelo; Goldoni, Guido; Di Felice, Rosa; Vallée, Fabrice; Del Fatti, Natalia; Banin, Uri; Sönnichsen, Carsten

    2011-06-28

    The optical response of hybrid metal-semiconductor nanoparticles exhibits different behaviors due to the proximity between the disparate materials. For some hybrid systems, such as CdS-Au matchstick-shaped hybrids, the particles essentially retain the optical properties of their original components, with minor changes. Other systems, such as CdSe-Au dumbbell-shaped nanoparticles, exhibit significant change in the optical properties due to strong coupling between the two materials. Here, we study the absorption of these hybrids by comparing experimental results with simulations using the discrete dipole approximation method (DDA) employing dielectric functions of the bare components as inputs. For CdS-Au nanoparticles, the DDA simulation provides insights on the gold tip shape and its interface with the semiconductor, information that is difficult to acquire by experimental means alone. Furthermore, the qualitative agreement between DDA simulations and experimental data for CdS-Au implies that most effects influencing the absorption of this hybrid system are well described by local dielectric functions obtained separately for bare gold and CdS nanoparticles. For dumbbell shaped CdSe-Au, we find a shortcoming of the electrodynamic model, as it does not predict the "washing out" of the optical features of the semiconductor and the metal observed experimentally. The difference between experiment and theory is ascribed to strong interaction of the metal and semiconductor excitations, which spectrally overlap in the CdSe case. The present study exemplifies the employment of theoretical approaches used to describe the optical properties of semiconductors and metal nanoparticles, to achieve better understanding of the behavior of metal-semiconductor hybrid nanoparticles.

  17. Hybridized tetraquarks

    NASA Astrophysics Data System (ADS)

    Esposito, A.; Pilloni, A.; Polosa, A. D.

    2016-07-01

    We propose a new interpretation of the neutral and charged X , Z exotic hadron resonances. Hybridized-tetraquarks are neither purely compact tetraquark states nor bound or loosely bound molecules but rather a manifestation of the interplay between the two. While meson molecules need a negative or zero binding energy, its counterpart for h-tetraquarks is required to be positive. The formation mechanism of this new class of hadrons is inspired by that of Feshbach metastable states in atomic physics. The recent claim of an exotic resonance in the Bs0 π± channel by the D0 Collaboration and the negative result presented subsequently by the LHCb Collaboration are understood in this scheme, together with a considerable portion of available data on X , Z particles. Considerations on a state with the same quantum numbers as the X (5568) are also made.

  18. Discrete Darboux transformation for discrete polynomials of hypergeometric type

    NASA Astrophysics Data System (ADS)

    Bangerezako, Gaspard

    1998-03-01

    The Darboux transformation, well known in second-order differential operator theory, is applied to the difference equations satisfied by the discrete hypergeometric polynomials (Charlier, Meixner-Kravchuk, Hahn).

  19. Discrete Dirac Structures and Implicit Discrete Lagrangian and Hamiltonian Systems

    NASA Astrophysics Data System (ADS)

    Leok, Melvin; Ohsawa, Tomoki

    2010-07-01

    We present discrete analogues of Dirac structures and the Tulczyjew's triple by considering the geometry of symplectic maps and their associated generating functions. We demonstrate that this framework provides a means of deriving discrete analogues of implicit Lagrangian and Hamiltonian systems. In particular, this yields implicit nonholonomic Lagrangian and Hamiltonian integrators. We also introduce discrete Lagrange-d'Alembert-Pontryagin and Hamilton-d'Alembert variational principles, which provide an alternative derivation of the same set of integration algorithms. In addition to providing a unified treatment of discrete Lagrangian and Hamiltonian mechanics in the more general setting of Dirac mechanics, it provides a generalization of symplectic and Poisson integrators to the broader category of Dirac integrators.

  20. Compensatory neurofuzzy model for discrete data classification in biomedical

    NASA Astrophysics Data System (ADS)

    Ceylan, Rahime

    2015-03-01

    Biomedical data is separated to two main sections: signals and discrete data. So, studies in this area are about biomedical signal classification or biomedical discrete data classification. There are artificial intelligence models which are relevant to classification of ECG, EMG or EEG signals. In same way, in literature, many models exist for classification of discrete data taken as value of samples which can be results of blood analysis or biopsy in medical process. Each algorithm could not achieve high accuracy rate on classification of signal and discrete data. In this study, compensatory neurofuzzy network model is presented for classification of discrete data in biomedical pattern recognition area. The compensatory neurofuzzy network has a hybrid and binary classifier. In this system, the parameters of fuzzy systems are updated by backpropagation algorithm. The realized classifier model is conducted to two benchmark datasets (Wisconsin Breast Cancer dataset and Pima Indian Diabetes dataset). Experimental studies show that compensatory neurofuzzy network model achieved 96.11% accuracy rate in classification of breast cancer dataset and 69.08% accuracy rate was obtained in experiments made on diabetes dataset with only 10 iterations.

  1. Hybrid molecularly imprinted membranes for targeted tocopherol: uses of cross-linked copolymer particles prepared by surfactant-free dispersion technique.

    PubMed

    Kobayashi, Takaomi; Faizal, Che ku M; Son, Le Trung

    2009-10-01

    Alpha-tocopherol (alpha-Toc) targeted membrane adsorbents were prepared by mixing alpha-Toc imprinted particles in polysulfone (PSf) scaffold. The alpha-Toc imprinted particles were prepared with high-shear dispersion copolymerization of alpha-Toc methacrylate (alpha-TMA) and divinylbenzene (DVB) in toluene and water in the agitation range of 300-13,500 rpm. The alpha-Toc groups in resultant imprinted particles were hydrolyzed with 2 M HCl and then the polymers were embedded in PSf membranes by phase inversion technique. The membrane exhibited good selective binding of alpha-Toc with high separation factors to its analogs. PMID:19722177

  2. Novel approach to data discretization

    NASA Astrophysics Data System (ADS)

    Borowik, Grzegorz; Kowalski, Karol; Jankowski, Cezary

    2015-09-01

    Discretization is an important preprocessing step in data mining. The data discretization method involves determining the ranges of values for numeric attributes, which ultimately represent discrete intervals for new attributes. The ranges for the proposed set of cuts are analyzed, in order to obtain a minimal set of ranges while retaining the possibility of classification. For this purpose, a special discernibility function can be constructed as a conjunction of alternative cuts set for each pair of different objects of different decisions- cuts discern these objects. However, the data mining methods based on discernibility matrix are insufficient for large databases. The purpose of this paper is the idea of implementation of a new data discretization algorithm that is based on statistics of attribute values and that avoids building the discernibility matrix explicitly. Evaluation of time complexity has shown that the proposed method is much more efficient than currently available solutions for large data sets.

  3. Discrete-element modeling of particulate aerosol flows

    SciTech Connect

    Marshall, J.S.

    2009-03-20

    A multiple-time step computational approach is presented for efficient discrete-element modeling of aerosol flows containing adhesive solid particles. Adhesive aerosol particulates are found in numerous dust and smoke contamination problems, including smoke particle transport in the lungs, particle clogging of heat exchangers in construction vehicles, industrial nanoparticle transport and filtration systems, and dust fouling of electronic systems and MEMS components. Dust fouling of equipment is of particular concern for potential human occupation on dusty planets, such as Mars. The discrete-element method presented in this paper can be used for prediction of aggregate structure and breakup, for prediction of the effect of aggregate formation on the bulk fluid flow, and for prediction of the effects of small-scale flow features (e.g., due to surface roughness or MEMS patterning) on the aggregate formation. After presentation of the overall computational structure, the forces and torques acting on the particles resulting from fluid motion, particle-particle collision, and adhesion under van der Waals forces are reviewed. The effect of various parameters of normal collision and adhesion of two particles are examined in detail. The method is then used to examine aggregate formation and particle clogging in pipe and channel flow.

  4. Concurrency and discrete event control

    NASA Technical Reports Server (NTRS)

    Heymann, Michael

    1990-01-01

    Much of discrete event control theory has been developed within the framework of automata and formal languages. An alternative approach inspired by the theories of process-algebra as developed in the computer science literature is presented. The framework, which rests on a new formalism of concurrency, can adequately handle nondeterminism and can be used for analysis of a wide range of discrete event phenomena.

  5. Discrete photonics in waveguide arrays.

    PubMed

    Moison, J M; Belabas, N; Minot, C; Levenson, J A

    2009-08-15

    In homogeneous arrays of coupled waveguides, Floquet-Bloch waves are known to travel freely across the waveguides. We introduce a systematic discussion of the built-in patterning of the coupling constant between neighboring waveguides. Key patterns provide functions such as redirecting, guiding, and focusing these waves, up to nonlinear all-optical routing. This opens the way to light control in a functionalized discrete space, i.e., discrete photonics.

  6. Identification of micro parameters for discrete element simulation of agglomerates

    NASA Astrophysics Data System (ADS)

    Palis, Stefan; Antonyuk, Sergiy; Dosta, Maksym; Heinrich, Stefan

    2013-06-01

    The mechanical behaviour of solid particles like agglomerates, granules or crystals strongly depends on their micro structure, e.g. structural defects and porosity. In order to model the mechanical behaviour of these inhomogeneous media the discrete element method has been proven to be an appropriate tool. The model parameters used are typically micro parameters like bond stiffness, particle-particle contact stiffness, strength of the bonds. Due to the lack of general methods for a direct micro parameter determination, normally laborious parameter adaptation has to be done in order to fit experiment and simulation. In this contribution a systematic and automatic way for parameter adaptation using real experiments is proposed. Due to the fact, that discrete element models are typically systems of differential equations of very high order, gradient based methods are not suitable. Hence, the focus will be on derivative free methods.

  7. Pilot-Wave Quantum Theory in Discrete Space and Time and the Principle of Least Action

    NASA Astrophysics Data System (ADS)

    Gluza, Janusz; Kosek, Jerzy

    2016-11-01

    The idea of obtaining a pilot-wave quantum theory on a lattice with discrete time is presented. The motion of quantum particles is described by a |Ψ |^2-distributed Markov chain. Stochastic matrices of the process are found by the discrete version of the least-action principle. Probability currents are the consequence of Hamilton's principle and the stochasticity of the Markov process is minimized. As an example, stochastic motion of single particles in a double-slit experiment is examined.

  8. Pilot-Wave Quantum Theory in Discrete Space and Time and the Principle of Least Action

    NASA Astrophysics Data System (ADS)

    Gluza, Janusz; Kosek, Jerzy

    2016-06-01

    The idea of obtaining a pilot-wave quantum theory on a lattice with discrete time is presented. The motion of quantum particles is described by a |Ψ |^2 -distributed Markov chain. Stochastic matrices of the process are found by the discrete version of the least-action principle. Probability currents are the consequence of Hamilton's principle and the stochasticity of the Markov process is minimized. As an example, stochastic motion of single particles in a double-slit experiment is examined.

  9. Gravity cutoff in theories with large discrete symmetries.

    PubMed

    Dvali, Gia; Redi, Michele; Sibiryakov, Sergey; Vainshtein, Arkady

    2008-10-10

    We set an upper bound on the gravitational cutoff in theories with exact quantum numbers of large N periodicity, such as Z(N) discrete symmetries. The bound stems from black hole physics. It is similar to the bound appearing in theories with N particle species, though a priori, a large discrete symmetry does not imply a large number of species. Thus, there emerges a potentially wide class of new theories that address the hierarchy problem by lowering the gravitational cutoff due to the existence of large Z(10(32))-type symmetries. PMID:18999587

  10. Sensitivities of particle impact noise detection

    NASA Technical Reports Server (NTRS)

    Keister, F. Z.; Caruso, S. V.

    1977-01-01

    The results of a study on Particle Impact Noise Detection commonly referred to as PIND testing is described. Certain sensitivities of PIND testing as applicable to hybrid microcircuits were determined, and techniques for removing particles from sealed hybrid packages were evaluated. Methods for freeing particles which have become trapped or hung up inside the hybrid package and, therefore, give no PIND test response were examined.

  11. Hybrid codes: Methods and applications

    SciTech Connect

    Winske, D. ); Omidi, N. )

    1991-01-01

    In this chapter we discuss hybrid'' algorithms used in the study of low frequency electromagnetic phenomena, where one or more ion species are treated kinetically via standard PIC methods used in particle codes and the electrons are treated as a single charge neutralizing massless fluid. Other types of hybrid models are possible, as discussed in Winske and Quest, but hybrid codes with particle ions and massless fluid electrons have become the most common for simulating space plasma physics phenomena in the last decade, as we discuss in this paper.

  12. Vortex Particle-Mesh methods for large scale LES of aircraft wakes

    NASA Astrophysics Data System (ADS)

    Chatelain, Philippe; Duponcheel, Matthieu; Marichal, Yves; Winckelmans, Grégoire

    2015-11-01

    Vortex methods solve the NS equations in vorticity-velocity formulation. The present Particle-Mesh variant exploits the advantages of a hybrid approach: advection is handled by the particles while the mesh allows the evaluation of the differential operators and the use of fast Poisson solvers (here a Fourier-based solver which allows for unbounded directions and inlet/outlet boundaries). A lifting line approach models the vorticity sources in the flow; its immersed treatment efficiently captures the development of vorticity from thin sheets into 3-D field. Large scale simulations of aircraft wakes (including ``encounter'' cases where a following aircraft flies into the wake) are presented, which also demonstrate the performance of the methodology: the adequate treatment of particle distortion, the high-order discretization, and the multiscale subgrid models allow to capture wake dynamics with minimal spurious dispersion and diffusion.

  13. Distributed Relaxation for Conservative Discretizations

    NASA Technical Reports Server (NTRS)

    Diskin, Boris; Thomas, James L.

    2001-01-01

    A multigrid method is defined as having textbook multigrid efficiency (TME) if the solutions to the governing system of equations are attained in a computational work that is a small (less than 10) multiple of the operation count in one target-grid residual evaluation. The way to achieve this efficiency is the distributed relaxation approach. TME solvers employing distributed relaxation have already been demonstrated for nonconservative formulations of high-Reynolds-number viscous incompressible and subsonic compressible flow regimes. The purpose of this paper is to provide foundations for applications of distributed relaxation to conservative discretizations. A direct correspondence between the primitive variable interpolations for calculating fluxes in conservative finite-volume discretizations and stencils of the discretized derivatives in the nonconservative formulation has been established. Based on this correspondence, one can arrive at a conservative discretization which is very efficiently solved with a nonconservative relaxation scheme and this is demonstrated for conservative discretization of the quasi one-dimensional Euler equations. Formulations for both staggered and collocated grid arrangements are considered and extensions of the general procedure to multiple dimensions are discussed.

  14. Discrete event simulation of continuous systems

    SciTech Connect

    Nutaro, James J

    2007-01-01

    Computer simulation of a system described by differential equations requires that some element of the system be approximated by discrete quantities. There are two system aspects that can be made discrete; time and state. When time is discrete, the differential equation is approximated by a difference equation (i.e., a discrete time system), and the solution is calculated at fixed points in time. When the state is discrete, the differential equation is approximated by a discrete event system. Events correspond to jumps through the discrete state space of the approximation.

  15. Geometry of discrete quantum computing

    NASA Astrophysics Data System (ADS)

    Hanson, Andrew J.; Ortiz, Gerardo; Sabry, Amr; Tai, Yu-Tsung

    2013-05-01

    Conventional quantum computing entails a geometry based on the description of an n-qubit state using 2n infinite precision complex numbers denoting a vector in a Hilbert space. Such numbers are in general uncomputable using any real-world resources, and, if we have the idea of physical law as some kind of computational algorithm of the universe, we would be compelled to alter our descriptions of physics to be consistent with computable numbers. Our purpose here is to examine the geometric implications of using finite fields Fp and finite complexified fields \\mathbf {F}_{p^2} (based on primes p congruent to 3 (mod4)) as the basis for computations in a theory of discrete quantum computing, which would therefore become a computable theory. Because the states of a discrete n-qubit system are in principle enumerable, we are able to determine the proportions of entangled and unentangled states. In particular, we extend the Hopf fibration that defines the irreducible state space of conventional continuous n-qubit theories (which is the complex projective space \\mathbf {CP}^{2^{n}-1}) to an analogous discrete geometry in which the Hopf circle for any n is found to be a discrete set of p + 1 points. The tally of unit-length n-qubit states is given, and reduced via the generalized Hopf fibration to \\mathbf {DCP}^{2^{n}-1}, the discrete analogue of the complex projective space, which has p^{2^{n}-1} (p-1)\\,\\prod _{k=1}^{n-1} ( p^{2^{k}}+1) irreducible states. Using a measure of entanglement, the purity, we explore the entanglement features of discrete quantum states and find that the n-qubit states based on the complexified field \\mathbf {F}_{p^2} have pn(p - 1)n unentangled states (the product of the tally for a single qubit) with purity 1, and they have pn + 1(p - 1)(p + 1)n - 1 maximally entangled states with purity zero.

  16. Automatic Mesh Coarsening for Discrete Ordinates Codes

    SciTech Connect

    Turner, Scott A.

    1999-03-11

    This paper describes the use of a ''mesh potential'' function for automatic coarsening of meshes in discrete ordinates neutral particle transport codes. For many transport calculations, a user may find it helpful to have the code determine a ''good'' neutronics mesh. The complexity of a problem involving millions of mesh cells, dozens of materials, and many energy groups makes it difficult to determine an adequate level of mesh refinement with a minimum number of cells. A method has been implemented in PARTISN (Parallel Time-dependent SN) to calculate a ''mesh potential'' in each original cell of a problem, and use this information to determine the maximum coarseness allowed in the mesh while maintaining accuracy in the solution. Results are presented for a simple x-y-z fuel/control/reflector problem.

  17. Discrete element modelling of bedload transport

    NASA Astrophysics Data System (ADS)

    Loyer, A.; Frey, P.

    2011-12-01

    Discrete element modelling (DEM) has been widely used in solid mechanics and in granular physics. In this type of modelling, each individual particle is taken into account and intergranular interactions are modelled with simple laws (e.g. Coulomb friction). Gravity and contact forces permit to solve the dynamical behaviour of the system. DEM is interesting to model configurations and access to parameters not directly available in laboratory experimentation, hence the term "numerical experimentations" sometimes used to describe DEM. DEM was used to model bedload transport experiments performed at the particle scale with spherical glass beads in a steep and narrow flume. Bedload is the larger material that is transported on the bed on stream channels. It has a great geomorphic impact. Physical processes ruling bedload transport and more generally coarse-particle/fluid systems are poorly known, arguably because granular interactions have been somewhat neglected. An existing DEM code (PFC3D) already computing granular interactions was used. We implemented basic hydrodynamic forces to model the fluid interactions (buoyancy, drag, lift). The idea was to use the minimum number of ingredients to match the experimental results. Experiments were performed with one-size and two-size mixtures of coarse spherical glass beads entrained by a shallow turbulent and supercritical water flow down a steep channel with a mobile bed. The particle diameters were 4 and 6mm, the channel width 6.5mm (about the same width as the coarser particles) and the channel inclination was typically 10%. The water flow rate and the particle rate were kept constant at the upstream entrance and adjusted to obtain bedload transport equilibrium. Flows were filmed from the side by a high-speed camera. Using image processing algorithms made it possible to determine the position, velocity and trajectory of both smaller and coarser particles. Modelled and experimental particle velocity and concentration depth

  18. Discrete cloud structure on Neptune

    NASA Astrophysics Data System (ADS)

    Hammel, H. B.

    1989-07-01

    Recent CCD imaging data for the discrete cloud structure of Neptune shows that while cloud features at CH4-band wavelengths are manifest in the southern hemisphere, they have not been encountered in the northern hemisphere since 1986. A literature search has shown the reflected CH4-band light from the planet to have come from a single discrete feature at least twice in the last 10 years. Disk-integrated photometry derived from the imaging has demonstrated that a bright cloud feature was responsible for the observed 8900 A diurnal variation in 1986 and 1987.

  19. Discrete Stochastic Simulation Methods for Chemically Reacting Systems

    PubMed Central

    Cao, Yang; Samuels, David C.

    2012-01-01

    Discrete stochastic chemical kinetics describe the time evolution of a chemically reacting system by taking into account the fact that in reality chemical species are present with integer populations and exhibit some degree of randomness in their dynamical behavior. In recent years, with the development of new techniques to study biochemistry dynamics in a single cell, there are increasing studies using this approach to chemical kinetics in cellular systems, where the small copy number of some reactant species in the cell may lead to deviations from the predictions of the deterministic differential equations of classical chemical kinetics. This chapter reviews the fundamental theory related to stochastic chemical kinetics and several simulation methods that are based on that theory. We focus on non-stiff biochemical systems and the two most important discrete stochastic simulation methods: Gillespie's Stochastic Simulation Algorithm (SSA) and the tau-leaping method. Different implementation strategies of these two methods are discussed. Then we recommend a relatively simple and efficient strategy that combines the strengths of the two methods: the hybrid SSA/tau-leaping method. The implementation details of the hybrid strategy are given here and a related software package is introduced. Finally, the hybrid method is applied to simple biochemical systems as a demonstration of its application. PMID:19216925

  20. Single electron tunneling in large scale nanojunction arrays with bisferrocene-nanoparticle hybrids.

    PubMed

    Karmakar, Shilpi; Kumar, Susmit; Marzo, Pasquale; Primiceri, Elisabetta; Di Corato, Riccardo; Rinaldi, Ross; Cozzi, Pier Giorgio; Bramanti, Alessandro Paolo; Maruccio, Giuseppe

    2012-04-01

    We report on the fabrication and single electron tunneling behaviour of large scale arrays of nanogap electrodes bridged by bisferrocene-gold nanoparticle hybrids (BFc-AuNP). Coulomb staircase was observed in the low temperature current-voltage curves measured on the junctions with asymmetric tunnel barriers. On the other hand, junctions with symmetric tunneling barrier exhibited mere nonlinear current voltage characteristics without discrete staircase. The experimental results agreed well with simulations based on the orthodox theory. The junction resistance showed thermally activated conduction behaviour at higher temperature. The overall voltage and temperature dependent results show that the transport behaviour of the large arrays of single particle devices obtained by a facile optical lithography and chemical etching process corresponds with the behaviour of single particle devices fabricated by other techniques like e-beam lithography and mechanical breaking methods.

  1. Topology optimization of double- and triple-layer grids using a hybrid methodology

    NASA Astrophysics Data System (ADS)

    Dehghani, M.; Mashayekhi, M.; Salajegheh, E.

    2016-08-01

    In this article, a hybrid methodology combining evolutionary structural optimization (ESO) and gravitational particle swarm (GPS) methods is proposed for topology optimization of double- and triple-layer grids. In the present methodology, which is called the ESO-GPS method, the size optimization of double- and triple-layer grids is first performed by ESO. Then, the outcomes of the ESO are used to improve the GPS through four modifications. Structural weight is minimized against constraints on the displacements of nodes, internal stresses and element slenderness ratio. The GPS is used to investigate the optimum topology of large-scale skeletal structures with discrete variables whose agents update their respective positions by the particle swarm optimization velocity and the acceleration of the gravitational search algorithm. The numerical results show that the proposed algorithm, the ESO-GPS, performs better than the GPS and the other methods presented in the literature.

  2. Model-Based Prognostics of Hybrid Systems

    NASA Technical Reports Server (NTRS)

    Daigle, Matthew; Roychoudhury, Indranil; Bregon, Anibal

    2015-01-01

    Model-based prognostics has become a popular approach to solving the prognostics problem. However, almost all work has focused on prognostics of systems with continuous dynamics. In this paper, we extend the model-based prognostics framework to hybrid systems models that combine both continuous and discrete dynamics. In general, most systems are hybrid in nature, including those that combine physical processes with software. We generalize the model-based prognostics formulation to hybrid systems, and describe the challenges involved. We present a general approach for modeling hybrid systems, and overview methods for solving estimation and prediction in hybrid systems. As a case study, we consider the problem of conflict (i.e., loss of separation) prediction in the National Airspace System, in which the aircraft models are hybrid dynamical systems.

  3. Some discrete multiple orthogonal polynomials

    NASA Astrophysics Data System (ADS)

    Arvesú, J.; Coussement, J.; van Assche, W.

    2003-04-01

    In this paper, we extend the theory of discrete orthogonal polynomials (on a linear lattice) to polynomials satisfying orthogonality conditions with respect to r positive discrete measures. First we recall the known results of the classical orthogonal polynomials of Charlier, Meixner, Kravchuk and Hahn (T.S. Chihara, An Introduction to Orthogonal Polynomials, Gordon and Breach, New York, 1978; R. Koekoek and R.F. Swarttouw, Reports of the Faculty of Technical Mathematics and Informatics No. 98-17, Delft, 1998; A.F. Nikiforov et al., Classical Orthogonal Polynomials of a Discrete Variable, Springer, Berlin, 1991). These polynomials have a lowering and raising operator, which give rise to a Rodrigues formula, a second order difference equation, and an explicit expression from which the coefficients of the three-term recurrence relation can be obtained. Then we consider r positive discrete measures and define two types of multiple orthogonal polynomials. The continuous case (Jacobi, Laguerre, Hermite, etc.) was studied by Van Assche and Coussement (J. Comput. Appl. Math. 127 (2001) 317-347) and Aptekarev et al. (Multiple orthogonal polynomials for classical weights, manuscript). The families of multiple orthogonal polynomials (of type II) that we will study have a raising operator and hence a Rodrigues formula. This will give us an explicit formula for the polynomials. Finally, there also exists a recurrence relation of order r+1 for these multiple orthogonal polynomials of type II. We compute the coefficients of the recurrence relation explicitly when r=2.

  4. Single electron tunneling in large scale nanojunction arrays with bisferrocene-nanoparticle hybrids

    NASA Astrophysics Data System (ADS)

    Karmakar, Shilpi; Kumar, Susmit; Marzo, Pasquale; Primiceri, Elisabetta; di Corato, Riccardo; Rinaldi, Ross; Cozzi, Pier Giorgio; Bramanti, Alessandro Paolo; Maruccio, Giuseppe

    2012-03-01

    We report on the fabrication and single electron tunneling behaviour of large scale arrays of nanogap electrodes bridged by bisferrocene-gold nanoparticle hybrids (BFc-AuNP). Coulomb staircase was observed in the low temperature current-voltage curves measured on the junctions with asymmetric tunnel barriers. On the other hand, junctions with symmetric tunneling barrier exhibited mere nonlinear current voltage characteristics without discrete staircase. The experimental results agreed well with simulations based on the orthodox theory. The junction resistance showed thermally activated conduction behaviour at higher temperature. The overall voltage and temperature dependent results show that the transport behaviour of the large arrays of single particle devices obtained by a facile optical lithography and chemical etching process corresponds with the behaviour of single particle devices fabricated by other techniques like e-beam lithography and mechanical breaking methods.We report on the fabrication and single electron tunneling behaviour of large scale arrays of nanogap electrodes bridged by bisferrocene-gold nanoparticle hybrids (BFc-AuNP). Coulomb staircase was observed in the low temperature current-voltage curves measured on the junctions with asymmetric tunnel barriers. On the other hand, junctions with symmetric tunneling barrier exhibited mere nonlinear current voltage characteristics without discrete staircase. The experimental results agreed well with simulations based on the orthodox theory. The junction resistance showed thermally activated conduction behaviour at higher temperature. The overall voltage and temperature dependent results show that the transport behaviour of the large arrays of single particle devices obtained by a facile optical lithography and chemical etching process corresponds with the behaviour of single particle devices fabricated by other techniques like e-beam lithography and mechanical breaking methods. Electronic supplementary

  5. Particle acceleration

    NASA Technical Reports Server (NTRS)

    Vlahos, L.; Machado, M. E.; Ramaty, R.; Murphy, R. J.; Alissandrakis, C.; Bai, T.; Batchelor, D.; Benz, A. O.; Chupp, E.; Ellison, D.

    1986-01-01

    Data is compiled from Solar Maximum Mission and Hinothori satellites, particle detectors in several satellites, ground based instruments, and balloon flights in order to answer fundamental questions relating to: (1) the requirements for the coronal magnetic field structure in the vicinity of the energization source; (2) the height (above the photosphere) of the energization source; (3) the time of energization; (4) transistion between coronal heating and flares; (5) evidence for purely thermal, purely nonthermal and hybrid type flares; (6) the time characteristics of the energization source; (7) whether every flare accelerates protons; (8) the location of the interaction site of the ions and relativistic electrons; (9) the energy spectra for ions and relativistic electrons; (10) the relationship between particles at the Sun and interplanetary space; (11) evidence for more than one acceleration mechanism; (12) whether there is single mechanism that will accelerate particles to all energies and also heat the plasma; and (13) how fast the existing mechanisms accelerate electrons up to several MeV and ions to 1 GeV.

  6. A FINITE-DIFFERENCE, DISCRETE-WAVENUMBER METHOD FOR CALCULATING RADAR TRACES

    EPA Science Inventory

    A hybrid of the finite-difference method and the discrete-wavenumber method is developed to calculate radar traces. The method is based on a three-dimensional model defined in the Cartesian coordinate system; the electromagnetic properties of the model are symmetric with respect ...

  7. A FINITE-DIFFERENCE, DISCRETE-WAVENUMBER METHOD FOR CALCULATING RADAR TRACES

    EPA Science Inventory

    A hybrid of the finite-difference method and the discrete-wavenumber method is developed to calculate radar traces. The method is based on a three-dimensional model defined in the Cartesian coordinate system; the electromag-netic properties of the model are symmetric with respect...

  8. Discrete electron forces in a nanoparticle-tunnel junction system

    NASA Astrophysics Data System (ADS)

    Suganuma, Y.; Trudeau, P.-E.; Dhirani, A.-A.; Leathem, B.; Shieh, B.

    2003-06-01

    According to the "orthodox" model for single electron tunneling, sudden changes in current-voltage characteristics of nanoparticle (NP)-tunnel junction (TJ) systems ["Coulomb blockade" (CB) and "Coulomb staircase" (CS) phenomena] arise fundamentally due to charge quantization. We have embedded NPs (˜2.5 nm in diameter) in the TJ of a hybrid scanning tunneling-atomic force microscope and have simultaneously measured current and forces generated in the system. We discuss an application to micromechanical switching actuated by single electrons. We also show that CB and CS phenomena are in fact associated with steplike changes in force, directly confirming the discrete charge nature of the phenomena.

  9. Discrete gauge symmetries in discrete MSSM-like orientifolds

    NASA Astrophysics Data System (ADS)

    Ibáñez, L. E.; Schellekens, A. N.; Uranga, A. M.

    2012-12-01

    Motivated by the necessity of discrete ZN symmetries in the MSSM to insure baryon stability, we study the origin of discrete gauge symmetries from open string sector U(1)'s in orientifolds based on rational conformal field theory. By means of an explicit construction, we find an integral basis for the couplings of axions and U(1) factors for all simple current MIPFs and orientifolds of all 168 Gepner models, a total of 32 990 distinct cases. We discuss how the presence of discrete symmetries surviving as a subgroup of broken U(1)'s can be derived using this basis. We apply this procedure to models with MSSM chiral spectrum, concretely to all known U(3)×U(2)×U(1)×U(1) and U(3)×Sp(2)×U(1)×U(1) configurations with chiral bi-fundamentals, but no chiral tensors, as well as some SU(5) GUT models. We find examples of models with Z2 (R-parity) and Z3 symmetries that forbid certain B and/or L violating MSSM couplings. Their presence is however relatively rare, at the level of a few percent of all cases.

  10. Method for coupling two-dimensional to three-dimensional discrete ordinates calculations

    SciTech Connect

    Thompson, J.L.; Emmett, M.B.; Rhoades, W.A.; Dodds, H.L. Jr.

    1985-01-01

    A three-dimensional (3-D) discrete ordinates transport code, TORT, has been developed at the Oak Ridge National Laboratory for radiation penetration studies. It is not feasible to solve some 3-D penetration problems with TORT, such as a building located a large distance from a point source, because (1) the discretized 3-D problem is simply too big to fit on the computer or (2) the computing time (and corresponding cost) is prohibitive. Fortunately, such problems can be solved with a hybrid approach by coupling a two-dimensional (2-D) description of the point source, which is assumed to be azimuthally symmetric, to a 3-D description of the building, the region of interest. The purpose of this paper is to describe this hybrid methodology along with its implementation and evaluation in the DOTTOR (Discrete Ordinates to Three-dimensional Oak Ridge Transport) code.

  11. HIGH ENERGY PARTICLE ACCELERATOR

    DOEpatents

    Courant, E.D.; Livingston, M.S.; Snyder, H.S.

    1959-04-14

    An improved apparatus is presented for focusing charged particles in an accelerator. In essence, the invention includes means for establishing a magnetic field in discrete sectors along the path of moving charged particles, the magnetic field varying in each sector in accordance with the relation. B = B/ sub 0/ STAln (r-r/sub 0/)/r/sub 0/!, where B/sub 0/ is the value of the magnetic field at the equilibrium orbit of radius r/sub 0/ of the path of the particles, B equals the magnetic field at the radius r of the chamber and n equals the magnetic field gradient index, the polarity of n being abruptly reversed a plurality of times as the particles travel along their arcuate path. With this arrangement, the particles are alternately converged towards the axis of their equillbrium orbit and diverged therefrom in successive sectors with a resultant focusing effect.

  12. DEM Particle Fracture Model

    SciTech Connect

    Zhang, Boning; Herbold, Eric B.; Homel, Michael A.; Regueiro, Richard A.

    2015-12-01

    An adaptive particle fracture model in poly-ellipsoidal Discrete Element Method is developed. The poly-ellipsoidal particle will break into several sub-poly-ellipsoids by Hoek-Brown fracture criterion based on continuum stress and the maximum tensile stress in contacts. Also Weibull theory is introduced to consider the statistics and size effects on particle strength. Finally, high strain-rate split Hopkinson pressure bar experiment of silica sand is simulated using this newly developed model. Comparisons with experiments show that our particle fracture model can capture the mechanical behavior of this experiment very well, both in stress-strain response and particle size redistribution. The effects of density and packings o the samples are also studied in numerical examples.

  13. Discrete Particle Dynamics Simulations of Adhesive Systems with Thermostatting

    NASA Astrophysics Data System (ADS)

    Pierce, Flint; Lechman, Jeremy; Hewson, John

    2012-02-01

    Aggregation/coagulation/flocculation processes are ubiquitous in modern industry from fields as diverse as waste water treatment, the food industry, algae biofuel production, and materials processing where control of the size and morphology of aggregates is paramount to the application of interest. Population balance models have historically been used with success in predicting aggregation kinetics and size distributions for these processes. However, even the most robust population balance schemes can lack an exact description of the underlying physical processes governing attractive or adhesive particulate matter suspended in a background medium, including finite aggregate strength and yield stress, restructuring length and time scales, and response to hydrodynamic forces. In order to elucidate these phenomena, We develop and use a JKR type model for simulating adhesive particulate matter in a background medium varying from dilute gas to liquid. We evaluate the time and length scales for restructuring/fragmentation that result from this model as a function of aggregate size and fractal dimension. We additionally introduce a method for pairwise thermostatting of the adhesive potential and discuss the applicability of this model to various adhesive systems.

  14. Discreteness noise versus force errors in N-body simulations

    NASA Technical Reports Server (NTRS)

    Hernquist, Lars; Hut, Piet; Makino, Jun

    1993-01-01

    A low accuracy in the force calculation per time step of a few percent for each particle pair is sufficient for collisionless N-body simulations. Higher accuracy is made meaningless by the dominant discreteness noise in the form of two-body relaxation, which can be reduced only by increasing the number of particles. Since an N-body simulation is a Monte Carlo procedure in which each particle-particle force is essentially random, i.e., carries an error of about 1000 percent, the only requirement is a systematic averaging-out of these intrinsic errors. We illustrate these assertions with two specific examples in which individual pairwise forces are deliberately allowed to carry significant errors: tree-codes on supercomputers and algorithms on special-purpose machines with low-precision hardware.

  15. Dark Energy from Discrete Spacetime

    PubMed Central

    Trout, Aaron D.

    2013-01-01

    Dark energy accounts for most of the matter-energy content of our universe, yet current theories of its origin rely on radical physical assumptions such as the holographic principle or controversial anthropic arguments. We give a better motivated explanation for dark energy, claiming that it arises from a small negative scalar-curvature present even in empty spacetime. The vacuum has this curvature because spacetime is fundamentally discrete and there are more ways for a discrete geometry to have negative curvature than positive. We explicitly compute this effect using a variant of the well known dynamical-triangulations (DT) model for quantum gravity. Our model predicts a time-varying non-zero cosmological constant with a current value, in natural units, in agreement with observation. This calculation is made possible by a novel characterization of the possible DT action values combined with numerical evidence concerning their degeneracies. PMID:24312502

  16. Dark energy from discrete spacetime.

    PubMed

    Trout, Aaron D

    2013-01-01

    Dark energy accounts for most of the matter-energy content of our universe, yet current theories of its origin rely on radical physical assumptions such as the holographic principle or controversial anthropic arguments. We give a better motivated explanation for dark energy, claiming that it arises from a small negative scalar-curvature present even in empty spacetime. The vacuum has this curvature because spacetime is fundamentally discrete and there are more ways for a discrete geometry to have negative curvature than positive. We explicitly compute this effect using a variant of the well known dynamical-triangulations (DT) model for quantum gravity. Our model predicts a time-varying non-zero cosmological constant with a current value, [Formula: see text] in natural units, in agreement with observation. This calculation is made possible by a novel characterization of the possible DT action values combined with numerical evidence concerning their degeneracies.

  17. A FORTRAN Program for Discrete Discriminant Analysis

    ERIC Educational Resources Information Center

    Boone, James O.; Brewer, James K.

    1976-01-01

    A Fortran program is presented for discriminant analysis of discrete variables. The program assumes discrete, nominal data with no distributional, variance-covariance assumptions. The program handles a maximum of fifty predictor variables and twelve outcome groups. (Author/JKS)

  18. Anomalies and Discrete Chiral Symmetries

    SciTech Connect

    Creutz, M.

    2009-09-07

    The quantum anomaly that breaks the U(1) axial symmetry of massless multi-flavored QCD leaves behind a discrete flavor-singlet chiral invariance. With massive quarks, this residual symmetry has a close connection with the strong CP-violating parameter theta. One result is that if the lightest quarks are degenerate, then a first order transition will occur when theta passes through pi. The resulting framework helps clarify when the rooting prescription for extrapolating in the number of flavors is valid.

  19. Observability of discretized partial differential equations

    NASA Technical Reports Server (NTRS)

    Cohn, Stephen E.; Dee, Dick P.

    1988-01-01

    It is shown that complete observability of the discrete model used to assimilate data from a linear partial differential equation (PDE) system is necessary and sufficient for asymptotic stability of the data assimilation process. The observability theory for discrete systems is reviewed and applied to obtain simple observability tests for discretized constant-coefficient PDEs. Examples are used to show how numerical dispersion can result in discrete dynamics with multiple eigenvalues, thereby detracting from observability.

  20. Flare Hybrids

    NASA Astrophysics Data System (ADS)

    Tomczak, M.; Dubieniecki, P.

    2015-12-01

    On the basis of the Solar Maximum Mission observations, Švestka ( Solar Phys. 121, 399, 1989) introduced a new class of flares, the so-called flare hybrids. When they start, they look like typical compact flares (phase 1), but later on, they look like flares with arcades of magnetic loops (phase 2). We summarize the characteristic features of flare hybrids in soft and hard X-rays as well as in the extreme ultraviolet; these features allow us to distinguish flare hybrids from other flares. In this article, additional energy release or long plasma cooling timescales are suggested as possible causes of phase 2. We estimate the frequency of flare hybrids, and study the magnetic configurations favorable for flare hybrid occurrence. Flare hybrids appear to be quite frequent, and the difference between the lengths of magnetic loops in the two interacting loop systems seem to be a crucial parameter for determining their characteristics.

  1. Hybrid-SPRITE MRI.

    PubMed

    Xiao, Dan; Balcom, Bruce J

    2013-10-01

    In a FID based frequency encoding MRI experiment the central part of k-space is not generally accessible due to the probe dead time. This portion of k-space is however crucial for image reconstruction. SPRITE (Single Point Ramped Imaging with T1 Enhancement), SPI with a linearly ramped phase encode gradient, has been employed to image short relaxation time systems for many years with great success. It is a robust imaging method in significant measure because it provides acquisition of high quality k-space origin data. We propose a new sampling scheme, termed hybrid-SPRITE, combining phase and frequency encoding to ensure high quality images with reduced acquisition times, reduced gradient duty cycle and increased sensitivity. In hybrid-SPRITE, numerous time domain points are collected to assist image reconstruction. An Inverse Non-uniform Discrete Fourier Transform (INDFT) is employed in 1D applications. A pseudo-polar grid is exploited in 2D hybrid-SPRITE for rapid and accurate image reconstruction. PMID:23916990

  2. Spurious haloes and discreteness-driven relaxation in cosmological simulations

    NASA Astrophysics Data System (ADS)

    Power, C.; Robotham, A. S. G.; Obreschkow, D.; Hobbs, A.; Lewis, G. F.

    2016-10-01

    There is strong evidence that cosmological N-body simulations dominated by warm dark matter (WDM) contain spurious or unphysical haloes, most readily apparent as regularly spaced low-mass haloes strung along filaments. We show that spurious haloes are a feature of traditional N-body simulations of cosmological structure formation models, including WDM and cold dark matter models, in which gravitational collapse proceeds in an initially anisotropic fashion, and arises naturally as a consequence of discreteness-driven relaxation. We demonstrate this using controlled N-body simulations of plane-symmetric collapse and show that spurious haloes are seeded at shell crossing by localized velocity perturbations induced by the discrete nature of the density field, and that their characteristic separation should be approximately the mean inter-particle separation of the N-body simulation, which is fixed by the mass resolution within the volume. Using cosmological N-body simulations in which particles are split into two collisionless components of fixed mass ratio, we find that the spatial distribution of the two components show signatures of discreteness-driven relaxation on both large and small scales. Adopting a spline kernel gravitational softening that is of order the comoving mean inter-particle separation helps to suppress the effect of discreteness-driven relaxation, but cannot eliminate it completely. These results provide further motivation for recent developments of new algorithms, which include, for example, revisions of the traditional N-body approach by means of spatially adaptive anistropric gravitational softenings or explicit solution of the evolution of dark matter in phase space.

  3. Hybrid Markov-mass action law model for cell activation by rare binding events: Application to calcium induced vesicular release at neuronal synapses

    PubMed Central

    Guerrier, Claire; Holcman, David

    2016-01-01

    Binding of molecules, ions or proteins to small target sites is a generic step of cell activation. This process relies on rare stochastic events where a particle located in a large bulk has to find small and often hidden targets. We present here a hybrid discrete-continuum model that takes into account a stochastic regime governed by rare events and a continuous regime in the bulk. The rare discrete binding events are modeled by a Markov chain for the encounter of small targets by few Brownian particles, for which the arrival time is Poissonian. The large ensemble of particles is described by mass action laws. We use this novel model to predict the time distribution of vesicular release at neuronal synapses. Vesicular release is triggered by the binding of few calcium ions that can originate either from the synaptic bulk or from the entry through calcium channels. We report here that the distribution of release time is bimodal although it is triggered by a single fast action potential. While the first peak follows a stimulation, the second corresponds to the random arrival over much longer time of ions located in the synaptic terminal to small binding vesicular targets. To conclude, the present multiscale stochastic modeling approach allows studying cellular events based on integrating discrete molecular events over several time scales. PMID:27752087

  4. Particle Shape Characterization of Lunar Regolith using Reflected Light Microscopy

    NASA Astrophysics Data System (ADS)

    McCarty, C. B.; Garcia, G. C.; Rickman, D.

    2014-12-01

    Automated identification of particles in lunar thin sections is necessary for practical measurement of particle shape, void characterization, and quantitative characterization of sediment fabric. This may be done using image analysis, but several aspects of the lunar regolith make such automations difficult. For example, many of the particles are shattered; others are aggregates of smaller particles. Sieve sizes of the particles span 5 orders of magnitude. The physical thickness of a thin section, at a nominal 30 microns, is large compared to the size of many of the particles. Image acquisition modes, such as SEM and reflected light, while superior to transmitted light, still have significant ambiguity as to the volume being sampled. It is also desirable to have a technique that is inexpensive, not resource intensive, and analytically robust. To this end, we have developed an image acquisition and processing protocol that identifies and delineates resolvable particles on the front surface of a lunar thin section using a petrographic microscope in reflected light. For a polished thin section, a grid is defined covering the entire thin section. The grid defines discrete images taken with 20% overlap, minimizing the number of particles that intersect image boundaries. In reflected light mode, two images are acquired at each grid location, with a closed aperture diaphragm. One image, A, is focused precisely on the front surface of the thin section. The second image, B, is made after the stage is brought toward the objective lens just slightly. A bright fringe line, analogous to a Becke line, appears inside all transparent particles at the front surface of the section in the second image. The added light in the bright line corresponds to a deficit around the particles. Particle identification is done using ImageJ and uses multiple steps. A hybrid 5x5 median filter is used to make images Af and Bf. This primarily removes very small particles just below the front surface

  5. 3D imaging of nanomaterials by discrete tomography.

    PubMed

    Batenburg, K J; Bals, S; Sijbers, J; Kübel, C; Midgley, P A; Hernandez, J C; Kaiser, U; Encina, E R; Coronado, E A; Van Tendeloo, G

    2009-05-01

    The field of discrete tomography focuses on the reconstruction of samples that consist of only a few different materials. Ideally, a three-dimensional (3D) reconstruction of such a sample should contain only one grey level for each of the compositions in the sample. By exploiting this property in the reconstruction algorithm, either the quality of the reconstruction can be improved significantly, or the number of required projection images can be reduced. The discrete reconstruction typically contains fewer artifacts and does not have to be segmented, as it already contains one grey level for each composition. Recently, a new algorithm, called discrete algebraic reconstruction technique (DART), has been proposed that can be used effectively on experimental electron tomography datasets. In this paper, we propose discrete tomography as a general reconstruction method for electron tomography in materials science. We describe the basic principles of DART and show that it can be applied successfully to three different types of samples, consisting of embedded ErSi(2) nanocrystals, a carbon nanotube grown from a catalyst particle and a single gold nanoparticle, respectively. PMID:19269094

  6. State-space supervision of reconfigurable discrete event systems

    SciTech Connect

    Garcia, H.E.; Ray, A.

    1995-12-31

    The Discrete Event Systems (DES) theory of supervisory and state feedback control offers many advantages for implementing supervisory systems. Algorithmic concepts have been introduced to assure that the supervising algorithms are correct and meet the specifications. It is often assumed that the supervisory specifications are invariant or, at least, until a given supervisory task is completed. However, there are many practical applications where the supervising specifications update at real time. For example, in a Reconfigurable Discrete Event System (RDES) architecture, a bank of supervisors is defined to accommodate each identified operational condition or different supervisory specifications. This adaptive supervisory control system changes the supervisory configuration to accept coordinating commands or to adjust for changes in the controlled process. This paper addresses reconfiguration at the supervisory level of hybrid systems along with a RDES underlying architecture. It reviews the state-based supervisory control theory and extends it to the paradigm of RDES and in view of process control applications. The paper addresses theoretical issues with a limited number of practical examples. This control approach is particularly suitable for hierarchical reconfigurable hybrid implementations.

  7. A novel electrochemical biosensor based on the hemin-graphene nano-sheets and gold nano-particles hybrid film for the analysis of hydrogen peroxide.

    PubMed

    Song, Haiyan; Ni, Yongnian; Kokot, Serge

    2013-07-25

    Hydrogen peroxide is an important analyte in biochemical, industrial and environmental systems. Therefore, development of novel rapid and sensitive analytical methods is useful. In this work, a hemin-graphene nano-sheets (H-GNs)/gold nano-particles (AuNPs) electrochemical biosensor for the detection of hydrogen peroxide (H2O2) was researched and developed; it was constructed by consecutive, selective modification of the GCE electrode. Performance of the H-GNs/AuNPs/GCE was investigated by chronoamperometry, and AFM measurements suggested that the graphene flakes thickness was ~1.3 nm and that of H-GNs was ~1.8 nm, which ultimately indicated that each hemin layer was ~0.25 nm. This biosensor exhibited significantly better electrocatalytic activity for the reduction of hydrogen peroxide in comparison with the simpler AuNPs/GCE and H-GNs/GCE; it also displayed a linear response for the reduction of H2O2 in the range of 0.3 μM to 1.8 mM with a detection limit of 0.11μM (SN(-1)=3), high sensitivity of 2774.8 μA mM(-1) cm(-2), and a rapid response, which reached 95% of the steady state condition within 5s. In addition, the biosensor was unaffected by many interfering substances, and was stable over time. Thus, it was demonstrated that this biosensor was potentially suitable for H2O2 analysis in many types of sample.

  8. Hybrid stochastic simplifications for multiscale gene networks

    PubMed Central

    Crudu, Alina; Debussche, Arnaud; Radulescu, Ovidiu

    2009-01-01

    Background Stochastic simulation of gene networks by Markov processes has important applications in molecular biology. The complexity of exact simulation algorithms scales with the number of discrete jumps to be performed. Approximate schemes reduce the computational time by reducing the number of simulated discrete events. Also, answering important questions about the relation between network topology and intrinsic noise generation and propagation should be based on general mathematical results. These general results are difficult to obtain for exact models. Results We propose a unified framework for hybrid simplifications of Markov models of multiscale stochastic gene networks dynamics. We discuss several possible hybrid simplifications, and provide algorithms to obtain them from pure jump processes. In hybrid simplifications, some components are discrete and evolve by jumps, while other components are continuous. Hybrid simplifications are obtained by partial Kramers-Moyal expansion [1-3] which is equivalent to the application of the central limit theorem to a sub-model. By averaging and variable aggregation we drastically reduce simulation time and eliminate non-critical reactions. Hybrid and averaged simplifications can be used for more effective simulation algorithms and for obtaining general design principles relating noise to topology and time scales. The simplified models reproduce with good accuracy the stochastic properties of the gene networks, including waiting times in intermittence phenomena, fluctuation amplitudes and stationary distributions. The methods are illustrated on several gene network examples. Conclusion Hybrid simplifications can be used for onion-like (multi-layered) approaches to multi-scale biochemical systems, in which various descriptions are used at various scales. Sets of discrete and continuous variables are treated with different methods and are coupled together in a physically justified approach. PMID:19735554

  9. On discrete symmetries for a whole Abelian model

    NASA Astrophysics Data System (ADS)

    Chauca, J.; Doria, R.

    2012-10-01

    Considering the whole concept applied to gauge theory a nonlinear abelian model is derived. A next step is to understand on the model properties. At this work, it will be devoted to discrete symmetries. For this, we will work based in two fields reference systems. This whole gauge symmetry allows to be analyzed through different sets which are the constructor basis {Dμ,Xiμ} and the physical basis {GμI}. Taking as fields reference system the diagonalized spin-1 sector, P, C, T and PCT symmetries are analyzed. They show that under this systemic model there are conservation laws driven for the parts and for the whole. It develops the meaning of whole-parity, field-parity and so on. However it is the whole symmetry that rules. This means that usually forbidden particles as pseudovector photons can be introduced through such whole abelian system. As result, one notices that the fields whole {GμI} manifest a quanta diversity. It involves particles with different spins, masses and discrete quantum numbers under a same gauge symmetry. It says that without violating PCT symmetry different possibilities on discrete symmetries can be accommodated.

  10. On discrete symmetries for a whole Abelian model

    SciTech Connect

    Chauca, J.; Doria, R.

    2012-09-24

    Considering the whole concept applied to gauge theory a nonlinear abelian model is derived. A next step is to understand on the model properties. At this work, it will be devoted to discrete symmetries. For this, we will work based in two fields reference systems. This whole gauge symmetry allows to be analyzed through different sets which are the constructor basis {l_brace}D{sub {mu}},X{sup i}{sub {mu}}{r_brace} and the physical basis {l_brace}G{sub {mu}I}{r_brace}. Taking as fields reference system the diagonalized spin-1 sector, P, C, T and PCT symmetries are analyzed. They show that under this systemic model there are conservation laws driven for the parts and for the whole. It develops the meaning of whole-parity, field-parity and so on. However it is the whole symmetry that rules. This means that usually forbidden particles as pseudovector photons can be introduced through such whole abelian system. As result, one notices that the fields whole {l_brace}G{sub {mu}I}{r_brace} manifest a quanta diversity. It involves particles with different spins, masses and discrete quantum numbers under a same gauge symmetry. It says that without violating PCT symmetry different possibilities on discrete symmetries can be accommodated.

  11. Simulation of Marine Hydrokinetic Turbines in Unsteady Flow using Vortex Particle Method

    NASA Astrophysics Data System (ADS)

    Sale, Danny; Aliseda, Alberto

    2013-11-01

    A vortex particle method has been developed to study the performance and wake characteristics of Marine Hydrokinetic turbines. The goals are to understand mean flow and turbulent eddy effects on wake evolution, and the unsteady loading on the rotor and support structures. The vorticity-velocity formulation of the Navier-Stokes equations are solved using a hybrid Lagrangian-Eulerian method involving both vortex particle and spatial mesh discretizations. Particle strengths are modified by vortex stretching, diffusion, and body forces; these terms in the vorticity transport equation involve differential operators and are computed more efficiently on a Cartesian mesh using finite differences. High-order and moment-conserving interpolations allow the particles and mesh to exchange field quantities and particle strengths. An immersed boundary method which introduces a penalization term in the vorticity transport equations provides an efficient way to satisfy the no-slip boundary condition on solid boundaries. To provide further computational speedup, we investigate the use of multicore processors and graphics processing units using the OpenMP and OpenCL interfaces within the Parallel Particle-Mesh Library.

  12. Finite-element-based discretization and regularization strategies for 3-D inverse electrocardiography.

    PubMed

    Wang, Dafang; Kirby, Robert M; Johnson, Chris R

    2011-06-01

    We consider the inverse electrocardiographic problem of computing epicardial potentials from a body-surface potential map. We study how to improve numerical approximation of the inverse problem when the finite-element method is used. Being ill-posed, the inverse problem requires different discretization strategies from its corresponding forward problem. We propose refinement guidelines that specifically address the ill-posedness of the problem. The resulting guidelines necessitate the use of hybrid finite elements composed of tetrahedra and prism elements. Also, in order to maintain consistent numerical quality when the inverse problem is discretized into different scales, we propose a new family of regularizers using the variational principle underlying finite-element methods. These variational-formed regularizers serve as an alternative to the traditional Tikhonov regularizers, but preserves the L(2) norm and thereby achieves consistent regularization in multiscale simulations. The variational formulation also enables a simple construction of the discrete gradient operator over irregular meshes, which is difficult to define in traditional discretization schemes. We validated our hybrid element technique and the variational regularizers by simulations on a realistic 3-D torso/heart model with empirical heart data. Results show that discretization based on our proposed strategies mitigates the ill-conditioning and improves the inverse solution, and that the variational formulation may benefit a broader range of potential-based bioelectric problems.

  13. Discreteness effects in population dynamics

    NASA Astrophysics Data System (ADS)

    Guevara Hidalgo, Esteban; Lecomte, Vivien

    2016-05-01

    We analyse numerically the effects of small population size in the initial transient regime of a simple example population dynamics. These effects play an important role for the numerical determination of large deviation functions of additive observables for stochastic processes. A method commonly used in order to determine such functions is the so-called cloning algorithm which in its non-constant population version essentially reduces to the determination of the growth rate of a population, averaged over many realizations of the dynamics. However, the averaging of populations is highly dependent not only on the number of realizations of the population dynamics, and on the initial population size but also on the cut-off time (or population) considered to stop their numerical evolution. This may result in an over-influence of discreteness effects at initial times, caused by small population size. We overcome these effects by introducing a (realization-dependent) time delay in the evolution of populations, additional to the discarding of the initial transient regime of the population growth where these discreteness effects are strong. We show that the improvement in the estimation of the large deviation function comes precisely from these two main contributions.

  14. Discrete Ordinates Solutions for Highly Forward Peaked Scattering

    SciTech Connect

    Sanchez, Richard; McCormick, Norman J.

    2004-07-15

    The limitations of asymptotic methods for numerically solving highly forward peaked scattering (HFPS) problems are reviewed before resorting to a discrete ordinates solution for such problems based on biased angular quadrature formulas to increase the precision of the angular representation and on source evaluation from cell-averaged angular fluxes to reduce memory requirements. Also, a twice-collided source is introduced to avoid numerical representation of singularities in the solution. As an example the propagation and spreading of a collimated particle beam in an HFPS medium has been calculated with a discrete ordinates diamond-differenced numerical solution of the transport equation in two-dimensional curvilinear cylindrical coordinates. The calculation was carried out for a strongly forward peaked Henyey-Greenstein scattering law for which Fokker-Planck asymptotic models are not valid. The results show promise for numerically calculated reference solutions based on accurate spatial representations for checking the accuracy of standard asymptotic models for these types of problems.

  15. Fabrication and optical enhancing properties of discrete supercrystals

    NASA Astrophysics Data System (ADS)

    Tebbe, Moritz; Lentz, Sarah; Guerrini, Luca; Fery, Andreas; Alvarez-Puebla, Ramon A.; Pazos-Perez, Nicolas

    2016-06-01

    Discrete gold nanoparticle crystals with tunable size and morphology are fabricated via a fast and inexpensive template-assisted method. The highly precise hierarchical organization of the plasmonic building blocks yields superstructures with outstanding behaviour for surface-enhanced Raman scattering analysis.Discrete gold nanoparticle crystals with tunable size and morphology are fabricated via a fast and inexpensive template-assisted method. The highly precise hierarchical organization of the plasmonic building blocks yields superstructures with outstanding behaviour for surface-enhanced Raman scattering analysis. Electronic supplementary information (ESI) available: UV-Vis spectra and TEM and SEM images of different particles and supercrystals. See DOI: 10.1039/c5nr09017b

  16. Lepton mixing patterns from a scan of finite discrete groups

    NASA Astrophysics Data System (ADS)

    Holthausen, Martin; Lim, Kher Sham; Lindner, Manfred

    2013-04-01

    The recent discovery of a non-zero value of the mixing angle θ13 has ruled out tri-bimaximal mixing as the correct lepton mixing pattern generated by some discrete flavor symmetry (barring large next-to-leading order corrections in concrete models). In this work we assume that neutrinos are Majorana particles and perform a general scan of all finite discrete groups with order less than 1536 to obtain their predictions for lepton mixing angles. To our surprise, the scan of over one million groups only yields 3 interesting groups that give lepton mixing patterns which lie within 3-sigma of the current best global fit values. A systematic way to categorize such groups and the implications for flavor symmetry are discussed.

  17. An extension of the OpenModelica compiler for using Modelica models in a discrete event simulation

    SciTech Connect

    Nutaro, James

    2014-11-03

    In this article, a new back-end and run-time system is described for the OpenModelica compiler. This new back-end transforms a Modelica model into a module for the adevs discrete event simulation package, thereby extending adevs to encompass complex, hybrid dynamical systems. The new run-time system that has been built within the adevs simulation package supports models with state-events and time-events and that comprise differential-algebraic systems with high index. Finally, although the procedure for effecting this transformation is based on adevs and the Discrete Event System Specification, it can be adapted to any discrete event simulation package.

  18. Discrete element modelling of subglacial sediment deformation

    NASA Astrophysics Data System (ADS)

    Christensen, A. D.; Egholm, D. L.; Piotrowski, J. A.; Tulaczyk, S.

    2012-04-01

    Soft, deformable sediments are often present under glaciers. Subglacial sediments deform under the differential load of the ice, and this causes the overlying glacier to accelerate its motion. Understanding the rheology of subglacial sediment is therefore important for models of glacial dynamics. Previous studies of the mechanical behaviour of subglacial sediments have primarily relied on analytical considerations and laboratory shearing experiments. As a novel approach, the Discrete Element Method (DEM) is used to explore the highly nonlinear dynamics of a granular bed that is exposed to stress conditions comparable to subglacial environments. The numerical approach allows close monitoring of the mechanical and rheological behaviour under a range of conditions. Of special interest is bed shear strength, strain distribution and -localization, mode of deformation, and role of effective normal pressure during shearing. As a calibration benchmark, results from laboratory ring-shear experiments on granular material are compared to similar numerical experiments. The continuously recorded stress dynamics in the laboratory shear experiments are compared to DEM experiments, and the micro-mechanical parameters in the contact model of the DEM code are calibrated to match the macroscopic Mohr-Coulomb failure criteria parameters, constrained from successive laboratory shear tests under a range of normal pressures. The data-parallel nature of the basic DEM formulation makes the problem ideal for utilizing the high arithmetic potential of modern general-purpose GPUs. Using the Nvidia Cuda C toolkit, the algorithm is formulated for spherical particles in three dimensions with a soft-body contact model. Scene rendering is performed using a custom Cuda ray-tracing algorithm. Efforts on optimization of the particle algorithm are discussed, and future plans of expansion are presented.

  19. User-interfaces for hybrid systems: Analysis and design through hybrid reachability

    NASA Astrophysics Data System (ADS)

    Oishi, Meeko Mitsuko Karen

    Hybrid systems combine discrete state dynamics, which model mode switching, with continuous state dynamics, which model the physical processes themselves. Applications of hybrid system theory to automated systems have traditionally assumed that the controller itself is an automaton which runs in parallel with the system under control. We model human interaction with hybrid systems, which involves the user; the automation's discrete mode-logic, and the underlying continuous dynamics of the physical system. Often in safety-critical systems, user-interfaces display a reduced set of information about the entire system, however must still provide adequate information and must not confuse the user. We present (1) a method of designing a discrete event system abstraction of the hybrid system, in order to verify or design user-interfaces for hybrid human-automation systems, and (2) the relationship between user-interfaces and discrete observability properties. Using a hybrid computational tool for reachability, we find the largest region in which the system can always remain---this is the safe region of operation. By implementing a controller which arises from this computation, we mathematically guarantee that this safe region is invariant. Assigning discrete states to the computed invariant regions, we create a discrete event system from this hybrid system with safety restrictions. This abstraction can then be used in existing interface verification and design methods. A user-interface, modeled as a discrete system, must, not only be reduced (extraneous information has been eliminated), but also "immediately observable". We derive conditions for immediate observability, in which the current state can be constructed from the current output and last occurring event. Based on finite state machine state-reduction techniques, we synthesize an output for remote user-interfaces which fulfills this property. Aircraft are prime examples of complex, safety-critical systems. In

  20. Hybrid Filter Membrane

    NASA Technical Reports Server (NTRS)

    Laicer, Castro; Rasimick, Brian; Green, Zachary

    2012-01-01

    Cabin environmental control is an important issue for a successful Moon mission. Due to the unique environment of the Moon, lunar dust control is one of the main problems that significantly diminishes the air quality inside spacecraft cabins. Therefore, this innovation was motivated by NASA s need to minimize the negative health impact that air-suspended lunar dust particles have on astronauts in spacecraft cabins. It is based on fabrication of a hybrid filter comprising nanofiber nonwoven layers coated on porous polymer membranes with uniform cylindrical pores. This design results in a high-efficiency gas particulate filter with low pressure drop and the ability to be easily regenerated to restore filtration performance. A hybrid filter was developed consisting of a porous membrane with uniform, micron-sized, cylindrical pore channels coated with a thin nanofiber layer. Compared to conventional filter media such as a high-efficiency particulate air (HEPA) filter, this filter is designed to provide high particle efficiency, low pressure drop, and the ability to be regenerated. These membranes have well-defined micron-sized pores and can be used independently as air filters with discreet particle size cut-off, or coated with nanofiber layers for filtration of ultrafine nanoscale particles. The filter consists of a thin design intended to facilitate filter regeneration by localized air pulsing. The two main features of this invention are the concept of combining a micro-engineered straight-pore membrane with nanofibers. The micro-engineered straight pore membrane can be prepared with extremely high precision. Because the resulting membrane pores are straight and not tortuous like those found in conventional filters, the pressure drop across the filter is significantly reduced. The nanofiber layer is applied as a very thin coating to enhance filtration efficiency for fine nanoscale particles. Additionally, the thin nanofiber coating is designed to promote capture of

  1. Observers for discrete-time nonlinear systems

    NASA Astrophysics Data System (ADS)

    Grossman, Walter D.

    Observer synthesis for discrete-time nonlinear systems with special applications to parameter estimation is analyzed. Two new types of observers are developed. The first new observer is an adaptation of the Friedland continuous-time parameter estimator to discrete-time systems. The second observer is an adaptation of the continuous-time Gauthier observer to discrete-time systems. By adapting these observers to discrete-time continuous-time parameter estimation problems which were formerly intractable become tractable. In addition to the two newly developed observers, two observers already described in the literature are analyzed and deficiencies with respect to noise rejection are demonstrated. Improved versions of these observers are proposed and their performance demonstrated. The issues of discrete-time observability, discrete-time system inversion, and optimal probing are also addressed.

  2. From discrete elements to continuum fields: Extension to bidisperse systems

    NASA Astrophysics Data System (ADS)

    Tunuguntla, Deepak R.; Thornton, Anthony R.; Weinhart, Thomas

    2016-07-01

    Micro-macro transition methods can be used to, both, calibrate and validate continuum models from discrete data obtained via experiments or simulations. These methods generate continuum fields such as density, momentum, stress, etc., from discrete data, i.e. positions, velocity, orientations and forces of individual elements. Performing this micro-macro transition step is especially challenging for non-uniform or dynamic situations. Here, we present a general method of performing this transition, but for simplicity we will restrict our attention to two-component scenarios. The mapping technique, presented here, is an extension to the micro-macro transition method, called coarse-graining, for unsteady two-component flows and can be easily extended to multi-component systems without any loss of generality. This novel method is advantageous; because, by construction the obtained macroscopic fields are consistent with the continuum equations of mass, momentum and energy balance. Additionally, boundary interaction forces can be taken into account in a self-consistent way and thus allow for the construction of continuous stress fields even within one element radius of the boundaries. Similarly, stress and drag forces can also be determined for individual constituents of a multi-component mixture, which is critical for several continuum applications, e.g. mixture theory-based segregation models. Moreover, the method does not require ensemble-averaging and thus can be efficiently exploited to investigate static, steady and time-dependent flows. The method presented in this paper is valid for any discrete data, e.g. particle simulations, molecular dynamics, experimental data, etc.; however, for the purpose of illustration we consider data generated from discrete particle simulations of bidisperse granular mixtures flowing over rough inclined channels. We show how to practically use our coarse-graining extension for both steady and unsteady flows using our open-source coarse

  3. Hybrid mesons

    NASA Astrophysics Data System (ADS)

    Meyer, C. A.; Swanson, E. S.

    2015-05-01

    A review of the theoretical and experimental status of hybrid hadrons is presented. The states π1(1400) , π1(1600) , and π1(2015) are thoroughly reviewed, along with experimental results from GAMS, VES, Obelix, COMPASS, KEK, CLEO, Crystal Barrel, CLAS, and BNL. Theoretical lattice results on the gluelump spectrum, adiabatic potentials, heavy and light hybrids, and transition matrix elements are discussed. These are compared with bag, string, flux tube, and constituent gluon models. Strong and electromagnetic decay models are described and compared to lattice gauge theory results. We conclude that while good evidence for the existence of a light isovector exotic meson exists, its confirmation as a hybrid meson awaits discovery of its iso-partners. We also conclude that lattice gauge theory rules out a number of hybrid models and provides a reference to judge the success of others.

  4. Hybrid diagnostic system: beacon-based exception analysis for multimissions - Livingstone integration

    NASA Technical Reports Server (NTRS)

    Park, Han G.; Cannon, Howard; Bajwa, Anupa; Mackey, Ryan; James, Mark; Maul, William

    2004-01-01

    This paper describes the initial integration of a hybrid reasoning system utilizing a continuous domain feature-based detector, Beacon-based Exceptions Analysis for Multimissions (BEAM), and a discrete domain model-based reasoner, Livingstone.

  5. Ideal shrinking and expansion of discrete sequences

    NASA Technical Reports Server (NTRS)

    Watson, Andrew B.

    1986-01-01

    Ideal methods are described for shrinking or expanding a discrete sequence, image, or image sequence. The methods are ideal in the sense that they preserve the frequency spectrum of the input up to the Nyquist limit of the input or output, whichever is smaller. Fast implementations that make use of the discrete Fourier transform or the discrete Hartley transform are described. The techniques lead to a new multiresolution image pyramid.

  6. Determinant Expressions for Discrete Integrable Maps

    NASA Astrophysics Data System (ADS)

    Sogo, Kiyoshi

    2006-08-01

    Explicit formulas for several discrete integrable maps with periodic boundary condition are obtained, which give the sequential time developments in a form of the quotient of successive determinants of tri-diagonal matrices. We can expect that such formulas make the corresponding numerical simulations simple and stable. The cases of discrete Lotka-Volterra and discrete KdV equations are demonstrated by using the common algorithm computing determinants of tri-diagonal matrices.

  7. Efficient evaluation of collisional energy transfer terms for plasma particle simulations

    NASA Astrophysics Data System (ADS)

    Turrell, A. E.; Sherlock, M.; Rose, S. J.

    2016-02-01

    Particle-based simulations, such as in particle-in-cell (PIC) codes, are widely used in plasma physics research. The analysis of particle energy transfers, as described by the second moment of the Boltzmann equation, is often necessary within these simulations. We present computationally efficient, analytically derived equations for evaluating collisional energy transfer terms from simulations using discrete particles. The equations are expressed as a sum over the properties of the discrete particles.

  8. Discretizing gravity in warped spacetime

    SciTech Connect

    Schwartz, Matthew; Randall, Lisa; Schwartz, Matthew D.; Thambyahpillai, Shiyamala

    2005-07-11

    We investigate the discretized version of the compact Randall-Sundrum model. By studying the mass eigenstates of the lattice theory, we demonstrate that for warped space, unlike for flat space, the strong coupling scale does not depend on the IR scale and lattice size. However, strong coupling does prevent us from taking the continuum limit of the lattice theory. Nonetheless, the lattice theory works in the manifestly holographic regime and successfully reproduces the most significant features of the warped theory. It is even in some respects better than the KK theory, which must be carefully regulated to obtain the correct physical results. Because it is easier to construct lattice theories than to find exact solutions to GR, we expect lattice gravity to be a useful tool for exploring field theory in curved space.

  9. Lepton mixing and discrete symmetries

    NASA Astrophysics Data System (ADS)

    Hernandez, D.; Smirnov, A. Yu.

    2012-09-01

    The pattern of lepton mixing can emerge from breaking a flavor symmetry in different ways in the neutrino and charged lepton Yukawa sectors. In this framework, we derive the model-independent conditions imposed on the mixing matrix by the structure of discrete groups of the von Dyck type which include A4, S4, and A5. We show that, in general, these conditions lead to at least two equations for the mixing parameters (angles and CP phase δ). These constraints, which correspond to unbroken residual symmetries, are consistent with nonzero 13 mixing and deviations from maximal 2-3 mixing. For the simplest case, which leads to an S4 model and reproduces the allowed values of the mixing angles, we predict δ=(90°-120°).

  10. PREFACE: DISCRETE '08: Symposium on Prospects in the Physics of Discrete Symmetries

    NASA Astrophysics Data System (ADS)

    Bernabéu, José; Botella, Francisco J.; Mavromatos, Nick E.; Mitsou, Vasiliki A.

    2009-07-01

    The Symposium DISCRETE'08 on Prospects in the Physics of Discrete Symmetries was held at the Instituto de Física Corpuscular (IFIC) in Valencia, Spain from 11 to 16 December 2008. IFIC is a joint centre of the Consejo Superior de Investigaciones Científicas (CSIC) and the Universitat de València (UVEG). The aim of the Symposium was to bring together experts on the field of Discrete Symmetries in order to discuss its prospects on the eve of the LHC era. The general state of the art for CP, T and CPT symmetries was reviewed and their interplay with Baryogenesis, Early Cosmology, Quantum Gravity, String Theory and the Dark Sector of the Universe was emphasised. Connections with physics beyond the Standard Model, in particular Supersymmetry, were investigated. Experimental implications in current and proposed facilities received particular attention. The scientific programme consisted of 24 invited Plenary Talks and 93 contributions selected among the submitted papers. Young researchers, in particular, were encouraged to submit an abstract. The Special Lecture on ''CERN and the Future of Particle Physics'', given by the CERN Director General Rolf-Dieter Heuer to close the Symposium, was of particular relevance. On the last day of the Symposium, an open meeting took place between Professor Heuer and the Spanish community of particle physics. The Symposium covered recent developments on the subject of Discrete Symmetries in the following topics: Quantum Vacuum Entanglement, Symmetrisation Principle CPT in Quantum Gravity and String Theory, Decoherence, Lorentz Violation Ultra-high-energy Messengers Time Reversal CP violation in the SM and beyond Neutrino Mass, Mixing and CP Baryogenesis, Leptogenesis Family Symmetries Supersymmetry and other searches Experimental Prospects: LHC, Super-B Factories, DAΦNE-2, Neutrino Beams The excellence of most of the presentations during the Symposium was pointed out by many participants. The broad spectrum of topics under the

  11. Particle Diffusion in an Inhomogeneous Medium

    ERIC Educational Resources Information Center

    Bringuier, E.

    2011-01-01

    This paper is an elementary introduction to particle diffusion in a medium where the coefficient of diffusion varies with position. The introduction is aimed at third-year university courses. We start from a simple model of particles hopping on a discrete lattice, in one or more dimensions, and then take the continuous-space limit so as to obtain…

  12. Comparison of hybrid Hall thruster model to experimental measurements

    NASA Astrophysics Data System (ADS)

    Scharfe, Michelle K.; Gascon, Nicolas; Cappelli, Mark A.; Fernandez, Eduardo

    2006-08-01

    A two-dimensional hybrid particle-in-cell numerical model has been constructed in the radial-axial plane with the intent of examining the physics governing Hall thruster operation. The electrons are treated as a magnetized quasi-one-dimensional fluid and the ions are treated as collisionless, unmagnetized discrete particles. The anomalously high electron conductivity experimentally observed in Hall thrusters is accounted for using experimental measurements of electron mobility in the Stanford Hall Thruster. While an experimental mobility results in improved simulation of electron temperature and electric potential relative to a Bohm-type model, results suggest that energy losses due to electron wall interactions may also be an important factor in accurately simulating plasma properties. Using a simplified electron wall damping model modified to produce general agreement with experimental measurements, an evaluation is made of differing treatments of electron mobility, background gas, neutral wall interactions, and charge exchange collisions. Although background gas results in two populations of neutrals, the increased neutral density has little effect on other plasma properties. Diffuse neutral wall interactions are in better agreement with experimental measurements than specular scattering. Also, charge exchange collisions result in an increase in average neutral velocity of 11% and a decrease in average ion velocity of 4% near the exit plane. The momentum exchange that occurs during charge exchange collisions is found to be negligible.

  13. Hybrid SCR

    SciTech Connect

    Jantzen, T.; Zammit, K.

    1996-01-01

    Hybrid selective catalytic reduction (SCR) systems consist of either a combination of SCR techniques (i.e. in-dust SCR combined with air heater SCR) or selective noncatalytic reduction (SNCR) in combination with SCR. These Hybrid SCR systems can offer substantial benefits in reduced cost and enhanced performance; however, their applicability is very unit specific. This paper presents the results of a study to document the current experience and develop a tool by which utilities can determine the applicability of Hybrid SCR to meet their NO{sub x} reduction goals, a guideline for selecting the best configuration, and a reference for developing the design parameters necessary to implement the technology. Hybrid SCR systems have been installed and demonstrated on utility boilers. The systems have included in-duct SCR combined with air heater SCR and SNCR combined with SCR as includes a review of the results of these demonstrations as well as comments on the applicability of those results for other utility systems. Finally this document provides a reference for the development of design parameters for the implementation of Hybrid SCR. There are a number of technical and commercial considerations which must be resolved prior to designing or procuring a Hybrid SCR system. The boiler operating, temperature and emissions data necessary for the final design are presented along with the process design variables which must be specified. Procurement suggestions are included to assist the user in addressing some of the more pertinent commercial issues.

  14. Scalar discrete nonlinear multipoint boundary value problems

    NASA Astrophysics Data System (ADS)

    Rodriguez, Jesus; Taylor, Padraic

    2007-06-01

    In this paper we provide sufficient conditions for the existence of solutions to scalar discrete nonlinear multipoint boundary value problems. By allowing more general boundary conditions and by imposing less restrictions on the nonlinearities, we obtain results that extend previous work in the area of discrete boundary value problems [Debra L. Etheridge, Jesus Rodriguez, Periodic solutions of nonlinear discrete-time systems, Appl. Anal. 62 (1996) 119-137; Debra L. Etheridge, Jesus Rodriguez, Scalar discrete nonlinear two-point boundary value problems, J. Difference Equ. Appl. 4 (1998) 127-144].

  15. A discrete event method for wave simulation

    SciTech Connect

    Nutaro, James J

    2006-01-01

    This article describes a discrete event interpretation of the finite difference time domain (FDTD) and digital wave guide network (DWN) wave simulation schemes. The discrete event method is formalized using the discrete event system specification (DEVS). The scheme is shown to have errors that are proportional to the resolution of the spatial grid. A numerical example demonstrates the relative efficiency of the scheme with respect to FDTD and DWN schemes. The potential for the discrete event scheme to reduce numerical dispersion and attenuation errors is discussed.

  16. Comparing Algorithms for Graph Isomorphism Using Discrete- and Continuous-Time Quantum Random Walks

    SciTech Connect

    Rudinger, Kenneth; Gamble, John King; Bach, Eric; Friesen, Mark; Joynt, Robert; Coppersmith, S. N.

    2013-07-01

    Berry and Wang [Phys. Rev. A 83, 042317 (2011)] show numerically that a discrete-time quan- tum random walk of two noninteracting particles is able to distinguish some non-isomorphic strongly regular graphs from the same family. Here we analytically demonstrate how it is possible for these walks to distinguish such graphs, while continuous-time quantum walks of two noninteracting parti- cles cannot. We show analytically and numerically that even single-particle discrete-time quantum random walks can distinguish some strongly regular graphs, though not as many as two-particle noninteracting discrete-time walks. Additionally, we demonstrate how, given the same quantum random walk, subtle di erences in the graph certi cate construction algorithm can nontrivially im- pact the walk's distinguishing power. We also show that no continuous-time walk of a xed number of particles can distinguish all strongly regular graphs when used in conjunction with any of the graph certi cates we consider. We extend this constraint to discrete-time walks of xed numbers of noninteracting particles for one kind of graph certi cate; it remains an open question as to whether or not this constraint applies to the other graph certi cates we consider.

  17. Comparing Algorithms for Graph Isomorphism Using Discrete- and Continuous-Time Quantum Random Walks

    DOE PAGES

    Rudinger, Kenneth; Gamble, John King; Bach, Eric; Friesen, Mark; Joynt, Robert; Coppersmith, S. N.

    2013-07-01

    Berry and Wang [Phys. Rev. A 83, 042317 (2011)] show numerically that a discrete-time quan- tum random walk of two noninteracting particles is able to distinguish some non-isomorphic strongly regular graphs from the same family. Here we analytically demonstrate how it is possible for these walks to distinguish such graphs, while continuous-time quantum walks of two noninteracting parti- cles cannot. We show analytically and numerically that even single-particle discrete-time quantum random walks can distinguish some strongly regular graphs, though not as many as two-particle noninteracting discrete-time walks. Additionally, we demonstrate how, given the same quantum random walk, subtle di erencesmore » in the graph certi cate construction algorithm can nontrivially im- pact the walk's distinguishing power. We also show that no continuous-time walk of a xed number of particles can distinguish all strongly regular graphs when used in conjunction with any of the graph certi cates we consider. We extend this constraint to discrete-time walks of xed numbers of noninteracting particles for one kind of graph certi cate; it remains an open question as to whether or not this constraint applies to the other graph certi cates we consider.« less

  18. Hybridized polymer matrix composites

    NASA Technical Reports Server (NTRS)

    London, A.

    1981-01-01

    Design approaches and materials are described from which are fabricated pyrostatic graphite/epoxy (Gr/Ep) laminates that show improved retention of graphite particulates when subjected to burning. Sixteen hybridized plus two standard Gr/Ep laminates were designed, fabricated, and tested in an effort to eliminate the release of carbon (graphite) fiber particles from burned/burning, mechanically disturbed samples. The term pyrostatic is defined as meaning mechanically intact in the presence of fire. Graphite particulate retentive laminates were constructed whose constituent materials, cost of fabrication, and physical and mechanical properties were not significantly different from existing Gr/Ep composites. All but one laminate (a Celion graphite/bis-maleimide polyimide) were based on an off-the-shelf Gr/Ep, the AS-1/3501-5A system. Of the 16 candidates studied, four thin (10-ply) and four thick (50-ply) hybridized composites are recommended.

  19. Hybrid plasma modeling.

    SciTech Connect

    Hopkins, Matthew Morgan; DeChant, Lawrence Justin.; Piekos, Edward Stanley; Pointon, Timothy David

    2009-02-01

    This report summarizes the work completed during FY2007 and FY2008 for the LDRD project ''Hybrid Plasma Modeling''. The goal of this project was to develop hybrid methods to model plasmas across the non-continuum-to-continuum collisionality spectrum. The primary methodology to span these regimes was to couple a kinetic method (e.g., Particle-In-Cell) in the non-continuum regions to a continuum PDE-based method (e.g., finite differences) in continuum regions. The interface between the two would be adjusted dynamically ased on statistical sampling of the kinetic results. Although originally a three-year project, it became clear during the second year (FY2008) that there were not sufficient resources to complete the project and it was terminated mid-year.

  20. Shock during PIND test frees particles

    NASA Technical Reports Server (NTRS)

    Caruso, S. V.; Keister, F. Z.

    1979-01-01

    Recent study on Particle-Impact Noise-Detection (PIND) shows impact at 1,500 to 4,000 G normally imparted to hybrid microcircuits during testing knocks loose stray trapped particle that can be subsequentially removed. Process may be 80 to 90 percent effective in removal of particles depending on type of test utilized.

  1. Tractable particle filters for robot fault diagnosis

    NASA Astrophysics Data System (ADS)

    Verma, Vandi

    Experience has shown that even carefully designed and tested robots may encounter anomalous situations. It is therefore important for robots to monitor their state so that anomalous situations may be detected in a timely manner. Robot fault diagnosis typically requires tracking a very large number of possible faults in complex non-linear dynamic systems with noisy sensors. Traditional methods either ignore the uncertainly or use linear approximations of nonlinear system dynamics. Such approximations are often unrealistic, and as a result faults either go undetected or become confused with non-fault conditions. Probability theory provides a natural representation for uncertainty, but an exact Bayesian solution for the diagnosis problem is intractable. Classical Monte Carlo methods, such as particle filters, suffer from substantial computational complexity. This is particularly true with the presence of rare, yet important events, such as many system faults. The thesis presents a set of complementary algorithms that provide an approach for computationally tractable fault diagnosis. These algorithms leverage probabilistic approaches to decision theory and information theory to efficiently track a large number of faults in a general dynamic system with noisy measurements. The problem of fault diagnosis is represented as hybrid (discrete/continuous) state estimation. Taking advantage of structure in the domain it dynamically concentrates computation in the regions of state space that are currently most relevant without losing track of less likely states. Experiments with a dynamic simulation of a six-wheel rocker-bogie rover show a significant improvement in performance over the classical approach.

  2. Multi-particle FEM modeling on microscopic behavior of 2D particle compaction

    NASA Astrophysics Data System (ADS)

    Zhang, Y. X.; An, X. Z.; Zhang, Y. L.

    2015-03-01

    In this paper, the discrete random packing and various ordered packings such as tetragonal and hexagonal close packed structures generated by discrete element method and honeycomb, which is manually generated were input as the initial packing structures into the multi-particle finite element model (FEM) to study their densification during compaction, where each particle is discretized as a FEM mesh. The macro-property such as relative density and micro-properties such as local morphology, stress, coordination number and densification mechanism obtained from various initial packings are characterized and analyzed. The results show that the coupling of discrete feature in particle scale with the continuous FEM in macro-scale can effectively conquer the difficulties in traditional FEM modeling, which provides a reasonable way to reproduce the compaction process and identify the densification mechanism more accurately and realistically.

  3. 5 CFR 572.102 - Agency discretion.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Agency discretion. 572.102 Section 572.102 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS TRAVEL AND TRANSPORTATION EXPENSES; NEW APPOINTEES AND INTERVIEWS § 572.102 Agency discretion. Payment of travel...

  4. Discretization vs. Rounding Error in Euler's Method

    ERIC Educational Resources Information Center

    Borges, Carlos F.

    2011-01-01

    Euler's method for solving initial value problems is an excellent vehicle for observing the relationship between discretization error and rounding error in numerical computation. Reductions in stepsize, in order to decrease discretization error, necessarily increase the number of steps and so introduce additional rounding error. The problem is…

  5. Current Density and Continuity in Discretized Models

    ERIC Educational Resources Information Center

    Boykin, Timothy B.; Luisier, Mathieu; Klimeck, Gerhard

    2010-01-01

    Discrete approaches have long been used in numerical modelling of physical systems in both research and teaching. Discrete versions of the Schrodinger equation employing either one or several basis functions per mesh point are often used by senior undergraduates and beginning graduate students in computational physics projects. In studying…

  6. Covariance control of discrete stochastic bilinear systems

    NASA Technical Reports Server (NTRS)

    Skelton, R. E.; Kherat, S. M.; Yaz, E.

    1991-01-01

    The covariances that certain bilinear stochastic discrete time systems may possess are characterized. An explicit parameterization of all controllers that assign such covariances is given. The state feedback assignability and robustness of the system are discussed from a deterministic point of view. This work extends the theory of covariance control for continuous time bilinear systems to a discrete time setting.

  7. Discrete/PWM Ballast-Resistor Controller

    NASA Technical Reports Server (NTRS)

    King, Roger J.

    1994-01-01

    Circuit offers low switching loss and automatic compensation for failure of ballast resistor. Discrete/PWM ballast-resistor controller improved shunt voltage-regulator circuit designed to supply power from high-resistance source to low-impedance bus. Provides both coarse discrete voltage levels (by switching of ballast resistors) and continuous fine control of voltage via pulse-width modulation.

  8. Discreteness and Gradience in Intonational Contrasts.

    ERIC Educational Resources Information Center

    Gussenhoven, Carlos

    1999-01-01

    Three experimental techniques that can be used to investigate the gradient of discrete nature of intonational differences, the semantic task, the imitation task, and the pitch range task are discussed and evaluated. It is pointed out that categorical perception is a sufficient but not a necessary, property of phonological discreteness. (Author/VWL)

  9. Dust grain coagulation modelling : From discrete to continuous

    NASA Astrophysics Data System (ADS)

    Paruta, P.; Hendrix, T.; Keppens, R.

    2016-07-01

    In molecular clouds, stars are formed from a mixture of gas, plasma and dust particles. The dynamics of this formation is still actively investigated and a study of dust coagulation can help to shed light on this process. Starting from a pre-existing discrete coagulation model, this work aims to mathematically explore its properties and its suitability for numerical validation. The crucial step is in our reinterpretation from its original discrete to a well-defined continuous form, which results in the well-known Smoluchowski coagulation equation. This opens up the possibility of exploiting previous results in order to prove the existence and uniqueness of a mass conserving solution for the evolution of dust grain size distribution. Ultimately, to allow for a more flexible numerical implementation, the problem is rewritten as a non-linear hyperbolic integro-differential equation and solved using a finite volume discretisation. It is demonstrated that there is an exact numerical agreement with the initial discrete model, with improved accuracy. This is of interest for further work on dynamically coupled gas with dust simulations.

  10. Study of Ray Effects in Discrete Ordinates Calculations.

    NASA Astrophysics Data System (ADS)

    Gomes, Luisa Maria Torres

    Ray effects, an inherent problem in the formulation of the discrete ordinates approximation to the transport equation, is studied in this research. In particular, the effectiveness of using Monte Carlo procedures to generate a first collision source or a second collision source is investigated. Monte Carlo procedures provide a general methodology that can be applied to the discrete ordinates solution of complex problems in either two- or three-dimensional geometries, for which ray effects are likely to occur. The Monte Carlo method, which is intrinsically free from ray effects, performs the transport of the source particle to the first collision site. The Monte Carlo estimated uncollided fluxes or first collided fluxes are used to compute the scattering sources in a format suitable for input into the DORT two-dimensional and the TORT three -dimensional discrete ordinates codes. The computational time and precision requirements of the Monte Carlo calculation are analyzed. Also, three procedures for estimating the second collision source with the modified version of MORSE are investigated. The results show that significant improvements are achieved in the solution of the test problems when using the first collision source and that virtual elimination of ray effects is realized when using the second collision source.

  11. A modular, partitioned, discrete element framework for industrial grain distribution systems with rotating machinery

    NASA Astrophysics Data System (ADS)

    Casas, Guillermo; Mukherjee, Debanjan; Celigueta, Miguel Angel; Zohdi, Tarek I.; Onate, Eugenio

    2015-11-01

    A modular discrete element framework is presented for large-scale simulations of industrial grain-handling systems. Our framework enables us to simulate a markedly larger number of particles than previous studies, thereby allowing for efficient and more realistic process simulations. This is achieved by partitioning the particle dynamics into distinct regimes based on their contact interactions, and integrating them using different time-steps, while exchanging phase-space data between them. The framework is illustrated using numerical experiments based on fertilizer spreader applications. The model predictions show very good qualitative and quantitative agreement with available experimental data. Valuable insights are developed regarding the role of lift vs drag forces on the particle trajectories in-flight, and on the role of geometric discretization errors for surface meshing in governing the emergent behavior of a system of particles.

  12. Active control of turbomachine discrete tones

    NASA Astrophysics Data System (ADS)

    Fleeter, Sanford

    This paper was directed at active control of discrete frequency noise generated by subsonic blade rows through cancellation of the blade row interaction generated propagating acoustic waves. First discrete frequency noise generated by a rotor and stator in a duct was analyzed to determine the propagating acoustic pressure waves. Then a mathematical model was developed to analyze and predict the active control of discrete frequency noise generated by subsonic blade rows through cancellation of the propagating acoustic waves, accomplished by utilizing oscillating airfoil surfaces to generate additional control propagating pressure waves. These control waves interact with the propagating acoustic waves, thereby, in principle, canceling the acoustic waves and thus, the far field discrete frequency tones. This model was then applied to a fan exit guide vane to investigate active airfoil surface techniques for control of the propagating acoustic waves, and thus the far field discrete frequency tones, generated by blade row interactions.

  13. Generalized exponential function and discrete growth models

    NASA Astrophysics Data System (ADS)

    Souto Martinez, Alexandre; Silva González, Rodrigo; Lauri Espíndola, Aquino

    2009-07-01

    Here we show that a particular one-parameter generalization of the exponential function is suitable to unify most of the popular one-species discrete population dynamic models into a simple formula. A physical interpretation is given to this new introduced parameter in the context of the continuous Richards model, which remains valid for the discrete case. From the discretization of the continuous Richards’ model (generalization of the Gompertz and Verhulst models), one obtains a generalized logistic map and we briefly study its properties. Notice, however that the physical interpretation for the introduced parameter persists valid for the discrete case. Next, we generalize the (scramble competition) θ-Ricker discrete model and analytically calculate the fixed points as well as their stabilities. In contrast to previous generalizations, from the generalized θ-Ricker model one is able to retrieve either scramble or contest models.

  14. Clutter from non-discrete seabed structures.

    PubMed

    Holland, Charles W; Ellis, Dale D

    2012-06-01

    Clutter, or discrete target-like returns, is the most significant problem in the employment of active sonar. It is well understood that discrete objects, which are of the same spatial scale as the target and which possess a significant impedance contrast to the surrounding ocean, can lead to clutter. Here a somewhat counter-intuitive result is shown: that discrete target-like returns can occur from slowly varying seabed structures. The range dependence of the seabed can be weak and smooth-due to changes in layer thicknesses, sound speed, or both. Thus, this clutter mechanism may be a viable hypothesis for areas in which seabed clutter has been observed, but no discrete features, buried or proud, could be found. By using a broadband source, the time-frequency evolution of this clutter could be a useful way to discriminate against other kinds of clutter; e.g., that due to discrete objects.

  15. Permitted and forbidden sets in discrete-time linear threshold recurrent neural networks.

    PubMed

    Yi, Zhang; Zhang, Lei; Yu, Jiali; Tan, Kok Kiong

    2009-06-01

    The concepts of permitted and forbidden sets enable a new perspective of the memory in neural networks. Such concepts exhibit interesting dynamics in recurrent neural networks. This paper studies the basic theories of permitted and forbidden sets of the linear threshold discrete-time recurrent neural networks. The linear threshold transfer function has been regarded as an adequate transfer function for recurrent neural networks. Networks with this transfer function form a class of hybrid analog and digital networks which are especially useful for perceptual computations. Networks in discrete time can directly provide algorithms for efficient implementation in digital hardware. The main contribution of this paper is to establish foundations of permitted and forbidden sets. Necessary and sufficient conditions for the linear threshold discrete-time recurrent neural networks are obtained for complete convergence, existence of permitted and forbidden sets, as well as conditionally multiattractivity, respectively. Simulation studies explore some possible interesting practical applications.

  16. Neutron streaming through shield ducts using a discrete ordinates/Monte Carlo method

    SciTech Connect

    Urban, W.T.; Baker, R.S.

    1993-08-18

    A common problem in shield design is determining the neutron flux that streams through ducts in shields and also that penetrates the shield after having traveled partway down the duct. Obviously the determination of the neutrons that stream down the duct can be computed in a straightforward manner using Monte Carlo techniques. On the other hand those neutrons that must penetrate a significant portion of the shield are more easily handled using discrete ordinates methods. A hybrid discrete ordinates/Monte Carlo cods, TWODANT/MC, which is an extension of the existing discrete ordinates code TWODANT, has been developed at Los Alamos to allow the efficient, accurate treatment of both streaming and deep penetration problems in a single calculation. In this paper we provide examples of the application of TWODANT/MC to typical geometries that are encountered in shield design and compare the results with those obtained using the Los Alamos Monte Carlo code MCNP{sup 3}.

  17. Codimension-Two Bifurcation, Chaos and Control in a Discrete-Time Information Diffusion Model

    NASA Astrophysics Data System (ADS)

    Ren, Jingli; Yu, Liping

    2016-07-01

    In this paper, we present a discrete model to illustrate how two pieces of information interact with online social networks and investigate the dynamics of discrete-time information diffusion model in three types: reverse type, intervention type and mutualistic type. It is found that the model has orbits with period 2, 4, 6, 8, 12, 16, 20, 30, quasiperiodic orbit, and undergoes heteroclinic bifurcation near 1:2 point, a homoclinic structure near 1:3 resonance point and an invariant cycle bifurcated by period 4 orbit near 1:4 resonance point. Moreover, in order to regulate information diffusion process and information security, we give two control strategies, the hybrid control method and the feedback controller of polynomial functions, to control chaos, flip bifurcation, 1:2, 1:3 and 1:4 resonances, respectively, in the two-dimensional discrete system.

  18. A general association between discrete auroras and ion precipitation from the tail

    NASA Technical Reports Server (NTRS)

    Lyons, L. R.; Fennell, J. F.; Vampola, A. L.

    1988-01-01

    Observations from the spinning polar-orbiting S3-3 satellite were used to compare the locations of discrete auroral arcs (defined to be regions containing particle distributions consistent with field-aligned potential drops of not less than 0.5 kV) with regions of isotropic ion precipitation. It was found that the regions of discrete aurora are almost exclusively confined to the region of isotropic ion precipitation at all local times studied (polar cap arcs and local times near noon were not considered). It was also found that, throughout the local time interval studied, the discrete aurora was generally associated with spatial structure and boundaries in the precipitating ions, indicating that arc generation may be associated with structure in the particle population within the tail current sheet.

  19. Discrete element thermomechanical modelling of rock cutting with valuation of tool wear

    NASA Astrophysics Data System (ADS)

    Rojek, Jerzy

    2014-05-01

    The paper presents a thermomechanical discrete element model of rock cutting process. The thermomechanical formulation of the discrete element method considers mechanical and thermal phenomena and their reciprocal influence. The thermal model developed for transient heat conduction problems takes into account conductive heat transfer at the contact between particles and convection on the free surface. The thermal and mechanical problems are coupled by consideration of: (1) heat generated due to friction which is calculated in the mechanical problem and passed to the thermal solution, (2) influence of thermal expansion on mechanical interaction between particles. Estimation of temperature dependent wear has been included into the contact model. The coupled problem is solved using the staggered scheme.The thermomechanical algorithm has been implemented in a discrete element program and applied to simulation of rock cutting with single pick of a dredge cutter head. Numerical results confirm good performance of the developed algorithm.

  20. MULTISCALE DISCRETIZATION OF SHAPE CONTOURS

    SciTech Connect

    Prasad, L.; Rao, R.

    2000-09-01

    We present an efficient multi-scale scheme to adaptively approximate the continuous (or densely sampled) contour of a planar shape at varying resolutions. The notion of shape is intimately related to the notion of contour, and the efficient representation of the contour of a shape is vital to a computational understanding of the shape. Any polygonal approximation of a planar smooth curve is equivalent to a piecewise constant approximation of the parameterized X and Y coordinate functions of a discrete point set obtained by densely sampling the curve. Using the Haar wavelet transform for the piecewise approximation yields a hierarchical scheme in which the size of the approximating point set is traded off against the morphological accuracy of the approximation. Our algorithm compresses the representation of the initial shape contour to a sparse sequence of points in the plane defining the vertices of the shape's polygonal approximation. Furthermore, it is possible to control the overall resolution of the approximation by a single, scale-independent parameter.