International Collaboration Enhances Cancer Screening Efforts

Cancer.gov

CGH is working with the International Agency for Research on CancerExit Disclaimer (IARC) and the Pan American Health Organization (PAHO) on the ESTAMPA Study, a multi-centric study of cervical cancer screening and triage with HPV testing.

Use of High Throughput Screening Data in IARC Monograph Evaluations (SOT)

EPA Science Inventory

Purpose: Evaluation of carcinogenic mechanisms serves a critical role in IARC monograph evaluations, and can lead to “upgrade” or “downgrade” of the carcinogenicity conclusions based on human and animal evidence alone. Three recent IARC monograph Working Groups (110, 112, and 11...

[Vinyl chloride and 1,2-dichloroethane: classification and assessment of carcinogenicity, guidelines, threshold values, and standards developed by national and international entities, organizations, and agencies].

PubMed

Binetti, R; Costamagna, F M; Marcello, I

2001-01-01

International, national and regulatory classification, evaluation, guidelines and occupational exposure values regarding vinyl chloride and 1,2-dichloroethane, carried out by European Union (EU). Environmental Protection Agency (US EPA), International Agency for Research on Cancer (IARC), Italian National Advisory Toxicological Committee (CCTN), Occupational Safety and Health Administration (OSHA), World Health Organization (WHO), National Institute for Occupational Safety and Health (NIOSH), American Conference of Governmental Industrial Hygienists (ACGIH) and other institutions, have been considered with particular reference to the carcinogenic effects. Moreover information is reported in support of classification and evaluation and a short historical review since early 1970s, when first evidence that occupational exposure to VC could lead to angiosarcoma was published.

Use of High Throughput Screening Data in IARC Monograph ...

EPA Pesticide Factsheets

Purpose: Evaluation of carcinogenic mechanisms serves a critical role in IARC monograph evaluations, and can lead to “upgrade” or “downgrade” of the carcinogenicity conclusions based on human and animal evidence alone. Three recent IARC monograph Working Groups (110, 112, and 113) pioneered analysis of high throughput in vitro screening data from the U.S. Environmental Protection Agency’s ToxCast program in evaluations of carcinogenic mechanisms. Methods: For monograph 110, ToxCast assay data across multiple nuclear receptors were used to test the hypothesis that PFOA acts exclusively through the PPAR family of receptors, with activity profiles compared to several prototypical nuclear receptor-activating compounds. For monographs 112 and 113, ToxCast assays were systematically evaluated and used as an additional data stream in the overall evaluation of the mechanistic evidence. Specifically, ToxCast assays were mapped to 10 “key characteristics of carcinogens” recently identified by an IARC expert group, and chemicals’ bioactivity profiles were evaluated both in absolute terms (number of relevant assays positive for bioactivity) and relative terms (ranking with respect to other compounds evaluated by IARC, using the ToxPi methodology). Results: PFOA activates multiple nuclear receptors in addition to the PPAR family in the ToxCast assays. ToxCast assays offered substantial coverage for 5 of the 10 “key characteristics,” with the greates

Coverage of skin cancer and recreational tanning in North American magazines before and after the landmark 2006 International Agency for Research on Cancer report.

PubMed

McWhirter, Jennifer E; Hoffman-Goetz, Laurie

2015-02-21

Skin cancer is an increasingly important global public health problem. Mass media is a key source of skin cancer information. We examined how media coverage of skin cancer has changed over time as a consequence of the release of a key public health report from the International Agency for Research on Cancer (IARC) in 2006, which linked ultraviolet (UV) radiation from indoor tanning and skin cancer. A directed content analysis of skin cancer and tanning coverage in 29 popular North American magazines (2001-2012) examined reporting of skin cancer risk factors, UV behaviors, and early detection in article text (n = 761) and images (n = 1267). Chi-square and correlational analyses were used determine whether coverage changed in relation to the 2006 IARC report. The total volume of articles about skin cancer and tanning increased modestly after the IARC report (χ (2) = 4.57, df = 1, p < .05); however, key IARC report messages (e.g., avoid indoor tanning, UV as a risk factor) were no more likely to be reported after compared to before the report. There were virtually no changes in the percentage of coverage for both risk factors and early detection information over time. There were some changes in the percentage of coverage about UV behaviors after the IARC report, but these variables were not directly related to the report. Magazines were more likely to encourage sunscreen use (χ (2) = 11.55, df = 1, p < .01) and less likely to promote the tanned look as attractive (χ (2) = 9.72, df = 1, p < .01) after the IARC report. It also became less common for magazines to promote sun avoidance (χ (2) = 6.82, df = 1, p < .01) and use of sunless tanners (χ (2) = 7.46, df = 1, p < .01) after the report. Despite a modest increase in volume of coverage post-IARC report, key messages from the report were not taken up by the media. While there have been some improvements in magazine reporting, there is a need for

International cancer seminars: a focus on esophageal squamous cell carcinoma.

PubMed

Murphy, G; McCormack, V; Abedi-Ardekani, B; Arnold, M; Camargo, M C; Dar, N A; Dawsey, S M; Etemadi, A; Fitzgerald, R C; Fleischer, D E; Freedman, N D; Goldstein, A M; Gopal, S; Hashemian, M; Hu, N; Hyland, P L; Kaimila, B; Kamangar, F; Malekzadeh, R; Mathew, C G; Menya, D; Mulima, G; Mwachiro, M M; Mwasamwaja, A; Pritchett, N; Qiao, Y-L; Ribeiro-Pinto, L F; Ricciardone, M; Schüz, J; Sitas, F; Taylor, P R; Van Loon, K; Wang, S-M; Wei, W-Q; Wild, C P; Wu, C; Abnet, C C; Chanock, S J; Brennan, P

2017-09-01

The International Agency for Research on Cancer (IARC) and the US National Cancer Institute (NCI) have initiated a series of cancer-focused seminars [Scelo G, Hofmann JN, Banks RE et al. International cancer seminars: a focus on kidney cancer. Ann Oncol 2016; 27(8): 1382-1385]. In this, the second seminar, IARC and NCI convened a workshop in order to examine the state of the current science on esophageal squamous cell carcinoma etiology, genetics, early detection, treatment, and palliation, was reviewed to identify the most critical open research questions. The results of these discussions were summarized by formulating a series of 'difficult questions', which should inform and prioritize future research efforts. Published by Oxford University Press on behalf of the European Society for Medical Oncology 2017. This work is written by US Government employees and is in the public domain in the US.

[Motivation and significance of IARC classification for mobile phone].

PubMed

L'Abbate, N

2011-01-01

In May 2011, the IARC Working Group discussed the possibility that exposure to RF-EMF (radiofrequency electromagnetic fields) have to produce an increased risk for brain tumors and evaluated the available literature on different categories of subjects exposed, including, among others, a Danish cohort study, five case-control studies and the largest multi-center case-control study (INTERPHONE) on the use of mobile phone and brain tumors, including glioma, meningioma and acoustic neuroma. The Working Group also examined a number of studies with objectives related to various mechanisms ofcarcerogenesis. The findings have been reviewed critically and generally assessed as "limited" among users of wireless phones for glioma and acoustic neuroma and "inappropriate" to draw conclusions for other types of tumors. The evidence from occupational and environmental exposures were considered "insufficient" in the same way. Given the limited evidence in humans and in experimental animals, the Working Group has classified a large majority the RF-EMF fields as "possibly carcinogenic to humans" (Group 2B). The Director of IARC has recommended, however,further research in the long-term use of mobile phones and adoption of pragmatic steps to reduce exposure, such as hands-free devices or sms.

Pooled exposure-response analyses and risk assessment for lung cancer in 10 cohorts of silica-exposed workers: an IARC multicentre study.

PubMed

Steenland, K; Mannetje, A; Boffetta, P; Stayner, L; Attfield, M; Chen, J; Dosemeci, M; DeKlerk, N; Hnizdo, E; Koskela, R; Checkoway, H

2001-11-01

Silica is one of the most common occupational exposures worldwide. In 1997 the International Agency for Research on Cancer (IARC) classified inhaled crystalline silica as a human carcinogen (group 1), but acknowledged limitations in the epidemiologic data, including inconsistencies across studies and the lack of extensive exposure-response data. We have conducted a pooled exposure-response analysis of 10 silica-exposed cohorts to investigate lung cancer. The pooled cohort included 65,980 workers (44,160 miners, 21,820 nominees), and 1,072 lung cancer deaths (663 miners, 409 nonminers). Follow-up has been extended for five of these cohorts beyond published data. Quantitative exposure estimates by job and calendar time were adopted, modified, or developed to permit common analyses by respirable silica (mg/m3) across cohorts. The log of cumulative exposure, with a 15-year lag, was a strong predictor of lung cancer (p = 0.0001), with consistency across studies (test for heterogeneity, p = 0.34). Results for the log of cumulative exposure were consistent between underground mines and other facilities. Categorical analyses by quintile of cumulative exposure resulted in a monotonic trend with odds ratios of 1.0. 1.0, 1.3, 1.5, 1.6. Analyses using a spline curve also showed a monotonic increase in risk with increasing exposure. The estimated excess lifetime risk (through age 75) of lung cancer for a worker exposed from age 20 to 65 at 0.1 mg/m3 respirable crystalline silica (the permissible level in many countries) was 1.1-1.7%, above background risks of 3-6%. Our results support the decision by the IARC to classify inhaled silica in occupational settings as a carcinogen, and suggest that the current exposure limits in many countries may be inadequate. These data represent the first quantitative exposure-response analysis and risk assessment for silica using data from multiple studies.

Fiber glass exposure and human respiratory system cancer risk: lack of evidence persists since 2001 IARC re-evaluation.

PubMed

Marsh, Gary M; Buchanich, Jeanine M; Youk, Ada O

2011-06-01

To determine whether IARC's 2001 decision to downgrade the classification of insulation glass wool from Group 2B to Group 3 remains valid in light of epidemiological evidence reported after 2001. We performed a systematic review of epidemiological evidence regarding respiratory cancer risks in relation to man-made vitreous fiber (MMVF) exposure before and after the 2001 IARC re-evaluation with focus on glass wool exposure and respiratory system cancer. Since 2001, three new community-based, case-control studies, two detailed analyses of existing cohort studies and two reviews/meta-analyses were published. These studies revealed no consistent evidence of an increased respiratory system cancer risk in relation to glass wool exposure. From our evaluation of the epidemiological evidence published since 2001, we conclude that IARC's 2001 decision to downgrade insulation glass wool from Group 2B to Group 3 remains valid. Copyright © 2011 Elsevier Inc. All rights reserved.

78 FR 36542 - International Energy Agency Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-18

... DEPARTMENT OF ENERGY International Energy Agency Meetings AGENCY: Department of Energy. ACTION: Notice of meetings. SUMMARY: The Industry Advisory Board (IAB) to the International Energy Agency (IEA.... Clark, Assistant General Counsel for International and National Security Programs, Department of Energy...

75 FR 12532 - International Energy Agency Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-16

... DEPARTMENT OF ENERGY International Energy Agency Meetings AGENCY: Department of Energy. ACTION: Notice of meetings. SUMMARY: The Industry Advisory Board (IAB) to the International Energy Agency (IEA...: Diana D. Clark, Assistant General for International and National Security Programs, Department of Energy...

EPA's evaluation of the carcinogenic potential of glyphosate

EPA Science Inventory

Recently, several international agencies have evaluated the carcinogenic potential of glyphosate. In March 2015, the International Agency for Research on Cancer (IARC), a subdivision of the World Health Organization (WHO), determined that glyphosate was a probable carcinogen (gro...

75 FR 67711 - International Energy Agency Meetings

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2010-11-03

... DEPARTMENT OF ENERGY International Energy Agency Meetings AGENCY: Department of Energy. ACTION: Notice of meetings. SUMMARY: The Industry Advisory Board (IAB) to the International Energy Agency (IEA... Security Programs, Department of Energy, 1000 [[Page 67712

78 FR 39670 - World Trade Center Health Program; Addition of Prostate Cancer to the List of WTC-Related Health...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-02

... International Agency for Research on Cancer (IARC). http://monographs.iarc.fr/ . Accessed May 15, 2013. Method 1... comments by any of the following methods: Federal eRulemaking Portal: http://www.regulations.gov . Follow.... Rulemaking History C. Methods Used by the Administrator To Determine Whether To Add Cancer or Types of Cancer...

78 FR 16665 - International Energy Agency Meetings

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2013-03-18

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76 FR 35869 - International Energy Agency meetings

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2011-06-20

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76 FR 14003 - International Energy Agency Meetings

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2011-03-15

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77 FR 61583 - International Energy Agency Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-10

... DEPARTMENT OF ENERGY International Energy Agency Meetings AGENCY: Department of Energy. ACTION: Notice of meetings. SUMMARY: The Industry Advisory Board (IAB) to the International Energy Agency (IEA... Energy, 1000 Independence Avenue SW., Washington, DC 20585, 202-586-5072. SUPPLEMENTARY INFORMATION: In...

75 FR 34724 - International Energy Agency Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-18

... DEPARTMENT OF ENERGY International Energy Agency Meetings AGENCY: Department of Energy. ACTION: Notice of Meetings. SUMMARY: The Industry Advisory Board (IAB) to the International Energy Agency (IEA... Energy, 1000 Independence Avenue, SW., Washington, DC 20585, 202-586-3417. SUPPLEMENTARY INFORMATION: In...

76 FR 69714 - International Energy Agency Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-09

... DEPARTMENT OF ENERGY International Energy Agency Meetings AGENCY: Department of Energy. ACTION: Notice of Meetings. SUMMARY: The Industry Advisory Board (IAB) to the International Energy Agency (IEA... Security Programs, Department of Energy, 1000 Independence Avenue SW., Washington, DC 20585, (202) 586-3417...

77 FR 16826 - International Energy Agency Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-22

... DEPARTMENT OF ENERGY International Energy Agency Meetings AGENCY: Department of Energy, DoE. ACTION: Notice of meetings. SUMMARY: The Industry Advisory Board (IAB) to the International Energy Agency..., Department of Energy, 1000 Independence Avenue SW., Washington, DC 20585, 202-586-3417. SUPPLEMENTARY...

The Perspectives of the International Agencies

ERIC Educational Resources Information Center

Hollander, Astrid

2005-01-01

An Inter-agency Panel of Technical and Vocational Education and Training (TVET) experts, drawn from seven United Nations and other international agencies, was one of the highlights in the programme of UNESCO's International Experts Meeting "Learning for Work, Citizenship and Sustainability" (Bonn, Germany, 25-28 October 2004). The Panel…

EFFECTIVE COLLECTION AGENCY USE: THE IMPORTANCE OF INTERNAL POLICIES.

PubMed

Scroggins, Robert C

2014-11-25

Increasing patient accountability for the cost of healthcare means physician practices likely will need to improve their internal collection processes and consider contracting with an outside collection agency. But choosing a good collection agency is the second priority. The first is establishing well-thought-out and specific internal procedures for collecting as much as possible before turning to an outside collection agency.

16 CFR 1500.14 - Products requiring special labeling under section 3(b) of the act.

Code of Federal Regulations, 2012 CFR

2012-01-01

... performing quantitative or qualitative analyses of art materials, which may yield information that is used by... scientific bodies, including the International Agency for Research on Cancer and the National Cancer... Agency for Research on Cancer (IARC). (iii) Pursuant to the LHAMA, the Commission has issued guidelines...

The Healthy Worker Effect and Nuclear Industry Workers

PubMed Central

Fornalski, Krzysztof W.; Dobrzyński, Ludwik

2010-01-01

The linear no-threshold (LNT) dose-effect relationship has been consistently used by most radiation epidemiologists to estimate cancer mortality risk. The large scattering of data by International Agency for Research on Cancer, IARC (Vrijheid et al. 2007; Therry-Chef et al. 2007; Cardis et al. 2007), interpreted in accordance with LNT, has been previously demonstrated (Fornalski and Dobrzyński 2009). Using conventional and Bayesian methods the present paper demonstrates that the standard mortality ratios (SMRs), lower in the IARC cohort of exposed nuclear workers than in the non exposed group, should be considered as a hormetic effect, rather than a healthy worker effect (HWE) as claimed by the IARC group. PMID:20585442

"Agency in Mobility": Towards a Conceptualisation of International Student Agency in Transnational Mobility

ERIC Educational Resources Information Center

Tran, Ly Thi; Vu, Thao Thi Phuong

2018-01-01

Student mobility is becoming a prominent phenomenon of tertiary education in the twenty-first century. Internationally mobile students' lived experiences are intimately linked to their potential to exercise agency in transnational mobility. However, the notion of agency within the context of student mobility has not been the explicit focus of…

Genetic toxicology of putative nongenotoxic carcinogens

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jackson, M.A.; Stack, H.F.; Waters, M.D.

1993-01-01

The report examines a group of putative nongenotoxic carcinogens that have been cited in the published literature. Using short-term test data from the US Environmental Protection Agency/International Agency for Research on Cancer genetic activity profile (EPA/IARC GAP) database, these agents are classified on the basis of their mutagenicity emphasizing three genetic endpoints: gene mutation, chromosomal aberration and aneuploidy. On the basis of results of short-term tests for these effects, criteria was defined for evidence of mutagenicity (and nonmutagenicity) these criteria were applied in classifying the group of putative nongenotoxic carcinogens. The results from this evaluation based on the EPA/IARC GAPmore » database are presented along with a summary of the short-term test data for each chemical and the relevant carcinogenicity results from the NTP, Gene-Tox and IARC databases. The data clearly demonstrate that many of the putative nongenotoxic carcinogens that have been adequately tested in short-term bioassays induce gene or chromosomal mutations or aneuploidy.« less

International Education: A Compendium of Federal Agency Programs.

ERIC Educational Resources Information Center

Owens, Becky, Comp.

Federal agency programs in support of international education are summarized in this report. The publication is designed to help readers discover unknown programs, more fully understand more familiar programs, and learn more about specific requirements for agencies where proposals have been unsuccessfully submitted in the past. Focus is directed…

Adapting a standardised international 24 h dietary recall methodology (GloboDiet software) for research and dietary surveillance in Korea.

PubMed

Park, Min Kyung; Park, Jin Young; Nicolas, Geneviève; Paik, Hee Young; Kim, Jeongseon; Slimani, Nadia

2015-06-14

During the past decades, a rapid nutritional transition has been observed along with economic growth in the Republic of Korea. Since this dramatic change in diet has been frequently associated with cancer and other non-communicable diseases, dietary monitoring is essential to understand the association. Benefiting from pre-existing standardised dietary methodologies, the present study aimed to evaluate the feasibility and describe the development of a Korean version of the international computerised 24 h dietary recall method (GloboDiet software) and its complementary tools, developed at the International Agency for Research on Cancer (IARC), WHO. Following established international Standard Operating Procedures and guidelines, about seventy common and country-specific databases on foods, recipes, dietary supplements, quantification methods and coefficients were customised and translated. The main results of the present study highlight the specific adaptations made to adapt the GloboDiet software for research and dietary surveillance in Korea. New (sub-) subgroups were added into the existing common food classification, and new descriptors were added to the facets to classify and describe specific Korean foods. Quantification methods were critically evaluated and adapted considering the foods and food packages available in the Korean market. Furthermore, a picture book of foods/dishes was prepared including new pictures and food portion sizes relevant to Korean diet. The development of the Korean version of GloboDiet demonstrated that it was possible to adapt the IARC-WHO international dietary tool to an Asian context without compromising its concept of standardisation and software structure. It, thus, confirms that this international dietary methodology, used so far only in Europe, is flexible and robust enough to be customised for other regions worldwide.

Agency Agreements Process Champion Support Intern

NASA Technical Reports Server (NTRS)

Miksa, Ember

2018-01-01

This document will provide information on the 2018 Spring semester NIFS Intern who represented the Office of Chief Financial Officer (OCFO) as a Reimbursable Accountant at Kennedy Space Center (KSC). This intern supported the Agency Agreements Process Champions and Team Lead, Susan Kroskey, Sandy Massey and Mecca Murphy, with major initiatives to advance the KSC OCFO's vision of creating and innovating healthy financial management practices that maximize the value of resources entrusted to NASA. These initiatives include, but are not limited to: updating the Agency Guidance and NASA Procedural Guidance 9090.1 Agreements, implementing a new budget structure to be utilized across all centers, submitting a Call Request (CRQ) to enhance non-federal customer reporting, initiating a discussion to incorporate a 3-year funding program for NASA agreements, and undertaking the Office of Inspector General (OIG) Audit. In support of these initiatives, this intern identified technical methods to enhance and reduce the workload of financial processes for reimbursable and non-reimbursable agreements, prepared reports in support of accounting functions, and performed administrative work and miscellaneous technical tasks in support of the OCFO as requested. In conclusion of the internship, the intern will become knowledgeable on reimbursable accounting, reimbursable policy, types of reimbursable agreements, the agreements process, estimated pricing reports, and the roles and responsibilities of the Financial Accounting and Financial Services offices.

CARCINOGENICITY OF HOUSEHOLD SOLID FUEL COMBUSTION AND OF HIGH-TEMPERATURE FRYING

EPA Science Inventory

In October, 2006, 19 scientists from eight countries met at the International Agency for Research on Cancer (IARC) in Lyon, France, to assess the carcinogenicity of household solid fuel combustion (coal and biomass) and of high-temperature frying. These assessments will be publi...

Species Specific Bio-accessibility Estimates of Arsenic in US Consumed Rice

EPA Science Inventory

Inorganic arsenic (iAs) has been classified as a Class I carcinogen by the International Agency for Research on Cancer (IARC). For non-occupationally exposed individuals, the two predominant exposure routes for arsenic are drinking water and diet. Drinking water exposures conta...

76 FR 71346 - Public Meeting and Request for Information: Carcinogen and Recommended Exposure Limit (REL...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-17

... experimental mammalian species as the result of any oral, respiratory or dermal exposure, or any other exposure... contrast, other organizations, such as the International Agency for Research on Cancer (IARC) and the... and quicker means of classifying chemicals. Qualitative and semi- quantitative approaches such as...

48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol. ...

48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol. ...

48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 3 2012-10-01 2012-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol. ...

48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 3 2014-10-01 2014-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol. ...

48 CFR 204.470 - U.S.-International Atomic Energy Agency Additional Protocol.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 3 2013-10-01 2013-10-01 false U.S.-International Atomic Energy Agency Additional Protocol. 204.470 Section 204.470 Federal Acquisition Regulations System DEFENSE... Information Within Industry 204.470 U.S.-International Atomic Energy Agency Additional Protocol. ...

Health technology assessment agencies: an international overview of organizational aspects.

PubMed

Martelli, Francesco; La Torre, Giuseppe; Di Ghionno, Elena; Staniscia, Tommaso; Neroni, Massimo; Cicchetti, Americo; Von Bremen, Konrade; Ricciardi, Walter

2007-01-01

The aim of the study is to make an international comparison of Health Technology Assessment (HTA) Agencies, to show their similarities and differences. An e-mail questionnaire was sent to thirty HTA agencies internationally. Questions related to the structure of the agency, the relationship with health-related institutions, the prescriptiveness of the decisions taken, the main core and the modalities to spread the assessment, and the type of funding. Twenty-four HTA Agencies answered the questionnaire: 25 percent in America, 4.2 percent in Australia, and 70.8 percent in Europe. Fifty-four percent of HTA Agencies are governmental institutions (83.3 percent have central government funding), while 62.5 percent have relationships with health-related governmental institutions. Of the agencies, 87 percent reported that their decisions are not prescriptive, while for 20.8 percent and 8.3 percent of them stated that this was the case totally or partially, respectively, especially for the governmental and American Agencies. Seventeen agencies (70.8 percent) declared their work on multiannual programs (77 percent of the governmental HTA Agencies and 100 percent of the American ones). The assessments mainly addressed diagnostic procedures (85.7 percent) and pharmaceuticals (25 percent). The most common way to disseminate results is by means of paper report (91.7 percent), followed by the Internet (16.7 percent), and seminars to expert audiences (12.5 percent). The comparative analysis of HTA Agencies showed that governmental and American Agencies have a profound impact on the prescriptiveness of their assessment, and this could be linked to the fact that these types of Agencies work on multiannual programs. European and American HTA Agencies have many similarities in terms of type of assessment, funding, and dissemination of results.

Diesel Exhaust and Lung Cancer-Aftermath of Becoming an IARC Group 1 Carcinogen.

PubMed

Silverman, Debra T

2018-06-01

The International Agency for Research on Cancer reclassified diesel exhaust from Group 2A (probably carcinogenic to humans) to Group 1 (carcinogenic to humans) in 2012. Since then, reevaluation and reanalysis of 2 major studies (Diesel Exhaust in Miners Study and Trucking Industry Particle Study) that were influential to the International Agency for Research on Cancer evaluation have replicated the original findings and demonstrated the suitability of these epidemiologic data for the quantitative risk assessment needed to set safe exposure limits in occupational and outdoor ambient environments. The challenge now is to protect the workers and general populations in urban areas from the carcinogenicity of diesel exhaust.

International Geoscience Workforce Trends: More Challenges for Federal Agencies

NASA Astrophysics Data System (ADS)

Groat, C. G.

2005-12-01

Concern about the decreasing number of students entering undergraduate geoscience programs has been chronic and, at times, acute over the past three decades. Despite dwindling populations of undergraduate majors, graduate programs have remained relatively robust, bolstered by international students. With Increasing competition for graduate students by universities in Europe, Japan, Australia, and some developing countries, and with procedural challenges faced by international students seeking entry into the United States and its universities, this supply source is threatened. For corporations operating on a global scale, the opportunity to employ students from and trained in the regions in which they operate is generally a plus. For U.S. universities that have traditionally supplied this workforce, the changing situation poses challenges, but also opportunities for creative international partnerships. Federal government science agencies face more challenges than opportunities in meeting workforce needs under both present and changing education conditions. Restrictions on hiring non-U.S. citizens into the permanent workforce have been a long-standing issue for federal agencies. Exceptions are granted only where they can document the absence of eligible U.S.-citizen candidates. The U.S. Geological Survey has been successful in doing this in its Mendenhall Postdoctoral Research Fellowship Program, but there has been no solution to the broader limitation. Under current and forecast workforce recruitment conditions, creativity, such as that evidenced by the Mendenhall program,will be necessary if federal agencies are to draw from the increasingly international geoscience talent pool. With fewer U.S. citizens in U.S. geoscience graduate programs and a growing number of advanced-degreed scientists coming from universities outside the U.S., the need for changes in federal hiring policies is heightened. The near-term liklihood of this is low and combined with the decline in

Religion, Education, and Secularism in International Agencies

ERIC Educational Resources Information Center

Stambach, Amy; Marshall, Katherine; Nelson, Matthew J.; Andreescu, Liviu; Kwayu, Aikande C.; Wexler, Philip; Hotam, Yotam; Fischer, Shlomo; El Bilawi, Hassan

2011-01-01

During the interwar years of the early twentieth century, and through at least the 1980s, education was seen by scholars, state leaders, and international agency representatives alike as a way to modernize and secularize underdeveloped communities. Arguments about the modernizing power of education did not erase or discount the presence of…

International Energy Agency Solar Heating and Cooling Program

NASA Astrophysics Data System (ADS)

Brooks, A. J.

This trip was undertaken to participate in and represent the United States Industry at the International Energy Agency (IEA) Solar Heating and Cooling Program (SHCP) Task 14 Workshop. The meeting took place at the A1 Bani Hotel in Rome Italy.

Genotoxicity Expert Panel review: weight of evidence evaluation of the genotoxicity of glyphosate, glyphosate-based formulations, and aminomethylphosphonic acid.

PubMed

Brusick, David; Aardema, Marilyn; Kier, Larry; Kirkland, David; Williams, Gary

2016-09-01

In 2015, the International Agency for Research on Cancer (IARC) published a monograph concluding there was strong evidence for genotoxicity of glyphosate and glyphosate formulations and moderate evidence for genotoxicity of the metabolite aminomethylphosphonic acid (AMPA). These conclusions contradicted earlier extensive reviews supporting the lack of genotoxicity of glyphosate and glyphosate formulations. The IARC Monograph concluded there was strong evidence of induction of oxidative stress by glyphosate, glyphosate formulations, and AMPA. The Expert Panel reviewed the genotoxicity and oxidative stress data considered in the IARC Monograph, together with other available data not considered by IARC. The Expert Panel defined and used a weight of evidence (WoE) approach that included ranking of studies and endpoints by the strength of their linkage to events associated with carcinogenic mechanisms. Importantly, the Expert Panel concluded that there was sufficient information available from a very large number of regulatory genotoxicity studies that should have been considered by IARC. The WoE approach, the inclusion of all relevant regulatory studies, and some differences in interpretation of individual studies led to significantly different conclusions by the Expert Panel compared with the IARC Monograph. The Expert Panel concluded that glyphosate, glyphosate formulations, and AMPA do not pose a genotoxic hazard and the data do not support the IARC Monograph genotoxicity evaluation. With respect to carcinogenicity classification and mechanism, the Expert Panel concluded that evidence relating to an oxidative stress mechanism of carcinogenicity was largely unconvincing and that the data profiles were not consistent with the characteristics of genotoxic carcinogens.

Availability of epidemiologic data on humans exposed to animal carcinogens. II. Chemical uses and production volume

DOE Office of Scientific and Technical Information (OSTI.GOV)

Karstadt, M.; Bobal, R.

1982-01-01

We report further findings of a survey of manufacturers, processors, and importers of chemicals determined by the International Agency for Research on Cancer (IARC) to be animal carcinogens, but whose carcinogenicity in humans was considered uncertain because of inadequate epidemiologic data. We requested epidemiologic studies from the companies marketing or using any of the 75 IARC animal carcinogens in commerce in the United States. Eighteen of the 75 IARC animal carcinogens had volumes listed of 10(6) lb/year or greater, with 8 of the 13 chemicals for which studies had been completed or are in progress in this ''high volume'' category.more » The use category with the largest number of chemicals was drugs--19 of the 75 IARC animal carcinogens were in this category. However, none of the 13 chemicals included in epidemiologic studies was a drug. Seven of the 13 chemicals included in studies were used primarily as pesticides. We received little information on dyes and dye intermediates, experimental carcinogens, and drugs, all of which are produced in relatively low volumes; these categories represent 42 of the 75 IARC animal carcinogens. Low volumes and declining usage/production appear to be barriers to performance of epidemiologic studies. Information we received suggests that sometimes the problem of low production volume may be avoided by studying users rather than production workers. Overall, however, we expect few additional epidemiologic studies of the 75 IARC animal carcinogens.« less

From hazard identification to weighing the benefits and drawbacks of prevention

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vainio, Harri; Weiderpass, Elisabete

2005-09-01

In this commentary, we briefly summarize and give examples of evaluations done by the International Agency for Research on Cancer, WHO (IARC-WHO, Lyon, France) about the identification of carcinogenic substances or agents and the evaluation of the efficacy and effectiveness of cancer preventive substances, agents or strategies. In the 1970's the IARC initiated a series of Monographs on the Evaluation of Carcinogenic Risks to Humans for the purposes of primary prevention. During the last 35 years of the IARC Monographs, many agents that are important to the public health perspective have been evaluated. The agent or exposure is described andmore » classified according to the wording of one of the following groups: group 1, carcinogenic to humans; group 2A, probably carcinogenic to humans; group 2B, possibly carcinogenic to humans; group 3, not classifiable as to its carcinogenicity to humans; group 4, probably not carcinogenic to humans. In 1997, the IARC started a new series of handbooks, the IARC Handbooks of Cancer Prevention, which aimed for the evaluation of efficacy and effectiveness of cancer preventive agents and strategies. The process of evaluation is quite similar to the IARC Monographs. In total, 10 Handbooks were published in topics such as mammography screening, cervical cancer screening, consumption of fruits and vegetables, cruciferous vegetables, and weight control and physical activity. We discuss in general terms ways of preventing cancer and of evaluating preventive strategies, giving as example mammography screening.« less

78 FR 15047 - Agency Information Collection Activities; Proposed Collection; Comments Requested: International...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-08

... Collection Activities; Proposed Collection; Comments Requested: International Terrorism Victim Expense.../collection: International Terrorism Victim Expense Reimbursement Program (ITVERP) Application. (3) The agency.... Government employees who are victims of acts of international terrorism that occur(red) outside of the United...

International Aid Agencies, Learner-Centred Pedagogy and Political Democratisation: A Critique.

ERIC Educational Resources Information Center

Tabulawa, Richard

2003-01-01

Since 1989, international aid agencies have shown a marked interest in and preference for learner-centered pedagogy. This change follows a shift in agency ideology from modernization theory to neoliberalism, which sees democratic social relations as a prerequisite to free-market capitalism. Thus, the pedagogy represents a process of Westernization…

International cooperation in the field of space life sciences: European Space Agency's (ESA) perspectives.

PubMed

Oser, H

1989-08-01

International cooperation in life sciences, as in any other of the space research fields, takes place at two distinct levels: scientist to scientist, or agency to agency. This article is more concerned with the agency to agency level, which involves the arrangements made between two partners for the flying of experiments and/or hardware on space missions. International cooperation is inherent to the European Space Agency (ESA), since it consists of 13 member states (Austria, Belgium, Denmark, France, Ireland, Italy, the Netherlands, Norway, Spain, Sweden, Switzerland, United Kingdom, and West Germany) and one associated member, Finland. ESA also has special cooperative arrangements with Canada. Life sciences research in ESA is carried out within the Microgravity Research Program, an optional program to which member states (in this case all but Austria and Ireland) contribute "a la carte," and receive their "share" accordingly. Therefore, many of the activities are naturally linked to international arrangements within the member states, and also to arrangements between the agencies, with life sciences being the dominant activity between NASA and ESA.

75 FR 6070 - Notice of Public Meeting on the International Atomic Energy Agency Basic Safety Standards Version...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-05

... Energy Agency Basic Safety Standards Version 3.0, Draft Safety Requirements DS379 AGENCY: Nuclear Regulatory Commission. ACTION: Notice of Public Meeting on the International Atomic Energy Agency Basic... development of U.S. Government comments on this International Atomic Energy Agency (IAEA) draft General Safety...

International Atomic Energy Agency Safeguards: Challenge and response

NASA Astrophysics Data System (ADS)

Spector, Leonard S.

2017-11-01

This article provides a critical review of the nuclear accounting and inspection system of the International Atomic Energy Agency (IAEA), known as "IAEA safeguards." The article focuses on the multiple challenges the Agency confronts in verifying that all nuclear activities in the countries under its safeguards system are being pursued for exclusively peaceful purposes. The principal challenges noted are those posed by: undeclared facilities, the development of enrichment and reprocessing capabilities, illicit procurement activities, denial of inspector access, difficulties in verifying absence of weaponization activities, and difficulties in establishing that all nuclear-relevant activities in a state are peaceful. The article is in the form of annotated PowerPoint briefing slides.

Exploring the utility of institutional theory in analysing international health agency stasis and change.

PubMed

Gómez, Eduardo J

2013-10-01

Of recent interest is the capacity of international health agencies to adapt to changes in the global health environment and country needs. Yet, little is known about the potential benefits of using social science institutional theory, such as path dependency and institutional change theory, to explain why some international agencies, such as the WHO and the Global Fund to Fight AIDS, Tuberculosis and Malaria, fail to adapt, whereas others, such as the World Bank and UNAIDS, have. This article suggests that these institutional theories can help to better understand these differences in international agency adaptive capacity, while highlighting new areas of policy research and analysis.

75 FR 30772 - Notice of Public Information Collections Being Reviewed by the U.S. Agency for International...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-02

... AGENCY FOR INTERNATIONAL DEVELOPMENT Notice of Public Information Collections Being Reviewed by the U.S. Agency for International Development; Comments Requested SUMMARY: U.S. Agency for... information technology. DATES: Submit comments on or before August 2, 2010. ADDRESSES: Send comments via e...

48 CFR 719.273 - The U.S. Agency for International Development (USAID) Mentor-Protégé Program.

Code of Federal Regulations, 2011 CFR

2011-10-01

... International Development (USAID) Mentor-Protégé Program. 719.273 Section 719.273 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS The U.S. Agency for International Development (USAID) Mentor-Protégé Program 719.273 The U.S. Agency for...

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2013-04-18

...; Comment Request; IEPS International Resource Information System (IRIS) AGENCY: Office of Postsecondary... System (IRIS). OMB Control Number: 1840-0759. Type of Review: a revision of an existing information... reporting system, International Resource Information System (IRIS) that IFLE uses to collect annual...

10 CFR 95.36 - Access by representatives of the International Atomic Energy Agency or by participants in other...

Code of Federal Regulations, 2014 CFR

2014-01-01

... 10 Energy 2 2014-01-01 2014-01-01 false Access by representatives of the International Atomic... Atomic Energy Agency or by participants in other international agreements. (a) Based upon written... an authorized representative of the International Atomic Energy Agency (IAEA) or other international...

10 CFR 95.36 - Access by representatives of the International Atomic Energy Agency or by participants in other...

Code of Federal Regulations, 2010 CFR

2010-01-01

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10 CFR 95.36 - Access by representatives of the International Atomic Energy Agency or by participants in other...

Code of Federal Regulations, 2012 CFR

2012-01-01

... 10 Energy 2 2012-01-01 2012-01-01 false Access by representatives of the International Atomic... Atomic Energy Agency or by participants in other international agreements. (a) Based upon written... an authorized representative of the International Atomic Energy Agency (IAEA) or other international...

10 CFR 95.36 - Access by representatives of the International Atomic Energy Agency or by participants in other...

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 2 2013-01-01 2013-01-01 false Access by representatives of the International Atomic... Atomic Energy Agency or by participants in other international agreements. (a) Based upon written... an authorized representative of the International Atomic Energy Agency (IAEA) or other international...

10 CFR 95.36 - Access by representatives of the International Atomic Energy Agency or by participants in other...

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 2 2011-01-01 2011-01-01 false Access by representatives of the International Atomic... Atomic Energy Agency or by participants in other international agreements. (a) Based upon written... an authorized representative of the International Atomic Energy Agency (IAEA) or other international...

External Peer Review Report on the Defense Contract Management Agency Office of Independent Assessment Internal Review Team

DTIC Science & Technology

2015-11-02

External Peer Review Report on the Defense Contract Management Agency Office of Independent Assessment Internal Review Team N O V E M B E R 2 , 2 0 1 5... MANAGEMENT AGENCY SUBJECT: External Peer Review Report on the Defense Contract Management Agency Office of Independent Assessment Internal Review Team...Report No. DODIG-2016-007) Attached is the External Peer Review Report on the Defense Contract Management Agency Office of Independent Assessment

48 CFR 470.202 - Acquisition of commodities for United States Agency for International Development (USAID) programs.

Code of Federal Regulations, 2010 CFR

2010-10-01

... for United States Agency for International Development (USAID) programs. 470.202 Section 470.202... ACQUISITIONS 470.202 Acquisition of commodities for United States Agency for International Development (USAID... organization to require, an ocean carrier to submit offers electronically through a Web-based system maintained...

77 FR 12364 - Agency Information Collection; Activity Under OMB Review: Reporting Required for International...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-29

... supplemental data for the International Civil Aviation Organization (ICAO). Comments are requested concerning.... 2138-0039. Title: Reporting Required for International Civil Aviation Organization (ICAO). Form No...-0002] Agency Information Collection; Activity Under OMB Review: Reporting Required for International...

The structures and the role of an international agency for the control of satellites

NASA Technical Reports Server (NTRS)

Dupuy, R. J.

1984-01-01

Legal questions involved in the liability of a proposed agency which would control internationally owned satellites for monitoring worldwide compliance with arms control agreements are discussed. Difficulties in acquiring the signed consent of all the relevant nations, and guaranteeing satisfactory compliance with the terms of such an agreement are noted. Additional problems to be solved comprise the construction of the ground based facilities and the satellites, the funding for the venture, and the reconciliation of the functions of the proposed agency with the sovereignty of individual states. The agency would gather, treat, and format data for signatories of arms control agreements and provide technical assistance in crisis conditions. It is concluded that the existence and functioning of the agency would reduce the amount of classified information and would consequently reduce the level of international tensions.

75 FR 39204 - Notice of Public Information Collections Being Reviewed by the U.S. Agency for International...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-08

... AGENCY FOR INTERNATIONAL DEVELOPMENT Notice of Public Information Collections Being Reviewed by... forms of information technology. DATES: Submit comments on or before September 7, 2010. ADDRESSES: Send...: Renewal of Information Collection. Purpose: The United States Agency for International Development (USAID...

75 FR 10207 - Notice of Public Information Collections being Reviewed by the U.S. Agency for International...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-05

... AGENCY FOR INTERNATIONAL DEVELOPMENT Notice of Public Information Collections being Reviewed by... information technology. DATES: Submit comments on or before May 4, 2010. FOR FURTHER INFORMATION CONTACT.... SUPPLEMENTARY INFORMATION: The U.S. Agency for International Development (USAID) has previously sought emergency...

48 CFR 719.273 - The U.S. Agency for International Development (USAID) Mentor-Protégé Program.

Code of Federal Regulations, 2010 CFR

2010-10-01

... International Development (USAID) Mentor-Protégé Program. 719.273 Section 719.273 Federal Acquisition.... Agency for International Development (USAID) Mentor-Protégé Program 719.273 The U.S. Agency for International Development (USAID) Mentor-Protégé Program. ...

NSSDC index of international scientific rocket launches ordered by sponsering country/agency

NASA Technical Reports Server (NTRS)

1972-01-01

International scientific rocket launches are listed by discipline codes and by sponsoring country/agencies identifications. Launch sites, experiments, approximate apogee, success and principle experimenters are also shown.

75 FR 39204 - Notice of Public Information Collections Being Reviewed by the U.S. Agency for International...

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2010-07-08

... AGENCY FOR INTERNATIONAL DEVELOPMENT Notice of Public Information Collections Being Reviewed by... information technology. DATES: Submit comments on or before September 7, 2010. FOR FURTHER INFORMATION CONTACT... this Information Collection is to enable the U.S. Agency for International Development (USAID) to...

77 FR 26824 - Agency Information Collection; Activity Under OMB Review; Reporting Required for International...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-07

... RITA 2008-0002] Agency Information Collection; Activity Under OMB Review; Reporting Required for International Civil Aviation Organization (ICAO) AGENCY: Research & Innovative Technology Administration (RITA... Reduction Act of 1995 (44 U.S.C. 3501 et seq.), this notice announces that the Information Collection...

Carcinogenicity of the insulation wools: reassessment of the IARC evaluation.

PubMed

Brown, R C; Davis, J M; Douglas, D; Gruber, U F; Hoskins, J A; Ilgren, E B; Johnson, N F; Rossiter, C E; Wagner, J C

1991-08-01

In assessing the health evidence concerning man-made mineral fibers, the chemical composition, surface activity, durability, and size of fibers have to be taken into account. Special-purpose fine glass fibers need to be separated from the insulation wools (glass, rock, and slag wool). The epidemiological evidence is sufficient to conclude that there has been no mesothelioma risk to workers producing or using glass wool, rock wool, or slag wool. The epidemiological studies have been large and powerful, and they show no evidence of a cause-effect relationship between lung cancer and exposure to glass wool, rock wool, or slag wool fibers. There is some evidence of a small cancer hazard attached to the manufacturing process in slag wool plants 20 to 50 years ago, when asbestos was used in some products and other carcinogenic substances were present. However, this hazard is not associated with any index of exposure to slag wool itself. Animal inhalation studies of ordinary insulation wools also show that there is no evidence of hazard associated with exposure to these relatively coarse, soluble fibers. The evidence of carcinogenicity is limited to experiments with special-purpose fine durable glass fibers or experimental fibers, and only when these fibers are injected directly into the pleural or peritoneal cavity. Multiple chronic inhalation studies of these same special-purpose fine glass fibers have not produced evidence of carcinogenicity. It is suggested that the present IARC evaluation of the carcinogenic risk of insulation wools should be revised to Category 3: not classifiable as to carcinogenicity to humans.

EUROSCAN INTERNATIONAL NETWORK MEMBER AGENCIES: THEIR STRUCTURE, PROCESSES, AND OUTPUTS.

PubMed

Packer, Claire; Simpson, Sue; de Almeida, Rosimary Terezinha

2015-01-01

The EuroScan International Network is a global network of publicly funded early awareness and alert (EAA) systems for health technologies. We describe the EuroScan member agency systems and methods, and highlight the potential for increased collaboration. EuroScan members completed postal questionnaires supplemented with telephone interviews in 2012 to elicit additional information and check equivalence of responses. Information was updated between March and May 2013. Fifteen of the seventeen member agencies responded. The principal purpose of agencies is to inform decisions on coverage or reimbursement of health services and decisions on undertaking secondary research. The main users of information are national governments; health professionals; health services purchasers, commissioners, and decision makers; and healthcare providers. Most EuroScan agencies are small with almost half having fewer than two whole time equivalent staff. Ten agencies use both active and passive identification approaches, four use only active approaches. Most start identification in the experimental or investigational stages of the technology life cycle. All agencies assessed technologies when they are between the investigational and established, but under diffusion stages. Barriers to collaboration revolve around different system aims, purposes, and requirements; a lack of staff, finance, or opportunity; language differences; and restrictions on dissemination. Although many barriers to collaboration were identified, the majority of agencies were supportive of increased collaboration either involving the whole EuroScan Network or between individual agencies. Despite differences in the detailed identification processes, members thought that this was the most feasible phase to develop additional collaboration.

75 FR 57251 - Notice of Public Information Collections Being Reviewed by the U.S. Agency for International...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-20

... Public Information Collections Being Reviewed by the U.S. Agency for International Development; Comments... collection techniques or other forms of information technology. DATES: Submit comments on or before November..., Information and Records Division, U.S. Agency for International Development, Room 2.07-106, RRB, Washington...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goodman, Julie, E-mail: jgoodman@gradientcorp.com

Background: The International Agency for Research on Cancer (IARC) recently developed a framework for evaluating mechanistic evidence that includes a list of 10 key characteristics of carcinogens. This framework is useful for identifying and organizing large bodies of literature on carcinogenic mechanisms, but it lacks sufficient guidance for conducting evaluations that fully integrate mechanistic evidence into hazard assessments. Objectives: We summarize the framework, and suggest approaches to strengthen the evaluation of mechanistic evidence using this framework. Discussion: While the framework is useful for organizing mechanistic evidence, its lack of guidance for implementation limits its utility for understanding human carcinogenic potential.more » Specifically, it does not include explicit guidance for evaluating the biological significance of mechanistic endpoints, inter- and intra-individual variability, or study quality and relevance. It also does not explicitly address how mechanistic evidence should be integrated with other realms of evidence. Because mechanistic evidence is critical to understanding human cancer hazards, we recommend that IARC develop transparent and systematic guidelines for the use of this framework so that mechanistic evidence will be evaluated and integrated in a robust manner, and concurrently with other realms of evidence, to reach a final human cancer hazard conclusion. Conclusions: IARC does not currently provide a standardized approach to evaluating mechanistic evidence. Incorporating the recommendations discussed here will make IARC analyses of mechanistic evidence more transparent, and lead to assessments of cancer hazards that reflect the weight of the scientific evidence and allow for scientifically defensible decision-making. - Highlights: • IARC has a revised framework for evaluating literature on carcinogenic mechanisms. • The framework is based on 10 key characteristics of carcinogens. • IARC should develop

Communicating confidence in the detection and attribution of trends relevant to climate change

NASA Astrophysics Data System (ADS)

Ebi, K. L.

2015-12-01

Readily understandable and consistent language for describing confidence in detection and attribution statements can be developed based on the approach used by the International Agency for Research on Cancer (IARC). IARC was founded in 1965 to provide government authorities with expert, independent, scientific opinion on the causes of human cancer. IARC developed four standard terms for evaluations of the strength of evidence for carcinogenicity arising from human and experimental animal data, and for the strength of mechanistic evidence. Evidence is categorized as sufficient, limited, inadequate, and lack of carcinogenicity. The IARC process then combines theory, evidence, and degree of agreement into a summary evaluation that includes concise statements of the principal line(s) of argument that emerged, the conclusions of the working group on the strength of the evidence for each group of studies, citations to indicate which studies were pivotal to these conclusions, and the reasons for any differential weighting of data. The summary IARC categories are: Group 1 for agents carcinogenic to humans; Group 2 includes Group 2A (probably carcinogenic to humans) or Group 2B (possibly carcinogenic to humans) on the basis of epidemiological and experimental evidence of carcinogenicity and mechanistic and other relevant data; Group 3 for agents is not classifiable as to its carcinogenicity to humans; and Group 4 for agents probably not carcinogenic to humans. There are obvious parallels with describing confidence in key findings on detection and attribution of a trend to anthropogenic climate change with the confidence statements used by the IARC. Developing and consistent application of similar categories along with accompanying explanations of the principal lines of evidence, would be a helpful step in clearing communicating the degree and sources of certainty in the findings of detection and attribution.

Engaging International Students: An Analysis of the Australian Universities Quality Agency (AUQA) Reports

ERIC Educational Resources Information Center

Burdett, Jane; Crossman, Joanna

2012-01-01

Purpose: Australia has enjoyed two decades of growth in international student enrolments. This phenomenon, combined with the evolution of quality assurance policy frameworks, has stimulated interest in the social and academic experiences of international students and their educational outcomes. The Australian Universities Quality Agency's (AUQA)…

War on Hunger: A Report from the Agency for International Development, December 1975.

ERIC Educational Resources Information Center

Rhoad, David L., Ed.

Produced by the Agency for International Development, this magazine presents articles and speeches on international development. Published monthly, the articles focus on developing nations and problems and areas of development. Typical issues offer articles on food and nutrition, education, disaster and humanitarian relief, U.S. government policy,…

Space-based radar for the United Nations's international satellite monitoring agency

NASA Astrophysics Data System (ADS)

Cantafio, L. J.

1984-12-01

A session of the United Nations General Assembly was held in May and June 1978 with the objective to discuss questions related to disarmament. It was decided to consider the establishment of an international Satellite Monitoring Agency (ISMA). The arising questions were studied, and two reports were prepared concerning such a monitoring agency. One report contained preliminary conclusions on the technical, legal, and financial implications of establishing an ISMA, while the second report contained an in-depth study. It was found that from a technical point of view the project appeared possible and feasible, and that there were no provisions in the international law prohibiting the proposed activities. The present investigation has been conducted under the assumption that an ISMA will be estabished. Attention is given to the requirements for the ISMA, the space-based radar design, radar system tradeoff data, critical technologies, and system weight, cost and schedule.

Health system strengthening in Myanmar during political reforms: perspectives from international agencies.

PubMed

Risso-Gill, Isabelle; McKee, Martin; Coker, Richard; Piot, Peter; Legido-Quigley, Helena

2014-07-01

Myanmar has undergone a remarkable political transformation in the last 2 years, with its leadership voluntarily transitioning from an isolated military regime to a quasi-civilian government intent on re-engaging with the international community. Decades of underinvestment have left the country underdeveloped with a fragile health system and poor health outcomes. International aid agencies have found engagement with the Myanmar government difficult but this is changing rapidly and it is opportune to consider how Myanmar can engage with the global health system strengthening (HSS) agenda. Nineteen semi-structured, face-to-face interviews were conducted with representatives from international agencies working in Myanmar to capture their perspectives on HSS following political reform. They explored their perceptions of HSS and the opportunities for implementation. Participants reported challenges in engaging with government, reflecting the disharmony between actors, economic sanctions and barriers to service delivery due to health system weaknesses and bureaucracy. Weaknesses included human resources, data and medical products/infrastructure and logistical challenges. Agencies had mixed views of health system finance and governance, identifying problems and also some positive aspects. There is little consensus on how HSS should be approached in Myanmar, but much interest in collaborating to achieve it. Despite myriad challenges and concerns, participants were generally positive about the recent political changes, and remain optimistic as they engage in HSS activities with the government.

Methods of international health technology assessment agencies for economic evaluations--a comparative analysis.

PubMed

Mathes, Tim; Jacobs, Esther; Morfeld, Jana-Carina; Pieper, Dawid

2013-09-30

The number of Health Technology Assessment (HTA) agencies increases. One component of HTAs are economic aspects. To incorporate economic aspects commonly economic evaluations are performed. A convergence of recommendations for methods of health economic evaluations between international HTA agencies would facilitate the adaption of results to different settings and avoid unnecessary expense. A first step in this direction is a detailed analysis of existing similarities and differences in recommendations to identify potential for harmonization. The objective is to provide an overview and comparison of the methodological recommendations of international HTA agencies for economic evaluations. The webpages of 127 international HTA agencies were searched for guidelines containing recommendations on methods for the preparation of economic evaluations. Additionally, the HTA agencies were requested information on methods for economic evaluations. Recommendations of the included guidelines were extracted in standardized tables according to 13 methodological aspects. All process steps were performed independently by two reviewers. Finally 25 publications of 14 HTA agencies were included in the analysis. Methods for economic evaluations vary widely. The greatest accordance could be found for the type of analysis and comparator. Cost-utility-analyses or cost-effectiveness-analyses are recommended. The comparator should continuously be usual care. Again the greatest differences were shown in the recommendations on the measurement/sources of effects, discounting and in the analysis of sensitivity. The main difference regarding effects is the focus either on efficacy or effectiveness. Recommended discounting rates range from 1.5%-5% for effects and 3%-5% for costs whereby it is mostly recommended to use the same rate for costs and effects. With respect to the analysis of sensitivity the main difference is that oftentimes the probabilistic or deterministic approach is recommended

Using an International p53 Mutation Database as a Foundation for an Online Laboratory in an Upper Level Undergraduate Biology Class

ERIC Educational Resources Information Center

Melloy, Patricia G.

2015-01-01

A two-part laboratory exercise was developed to enhance classroom instruction on the significance of p53 mutations in cancer development. Students were asked to mine key information from an international database of p53 genetic changes related to cancer, the IARC TP53 database. Using this database, students designed several data mining activities…

75 FR 75952 - U.S. Agency for International Mandatory Declassification Review Address

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-07

... Development. ACTION: Notice. SUMMARY: Pursuant to the Information Security Oversight Offices Classified National Security Information Directive No. 1, this notice provides the U.S. Agency for International... public in advising them where to send such requests for declassification review. FOR FURTHER INFORMATION...

22 CFR Appendix A to Part 233 - Application for Compensation United States Agency for International Development Washington, DC 20523

Code of Federal Regulations, 2014 CFR

2014-04-01

... Agency for International Development Washington, DC 20523 A Appendix A to Part 233 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT HASHEMITE KINGDOM OF JORDAN LOAN GUARANTEES ISSUED UNDER THE FURTHER CONTINUING APPROPRIATIONS ACT, 2013, DIV. F, PUB. L. 113-6-STANDARD TERMS AND CONDITIONS Pt. 233, App. A...

How did international agencies perceive the avian influenza problem? The adoption and manufacture of the 'One World, One Health' framework.

PubMed

Chien, Yu-Ju

2013-02-01

Over the past few years, a 'One World, One Health' (OWOH) policy framework has become the guiding principle for international responses to avian influenza and other zoonotic infectious diseases. Several specialised inter-governmental agencies, including the World Health Organization, the Food and Agricultural Organization and World Organization for Animal Health, jointly endorsed and promoted this framework. This article attempts to explain why international agencies advocated OWOH despite its vagueness. By examining how these international agencies gradually reframed avian flu problems, this article illustrates the crucial roles of international agencies in constructing disease knowledge and relevant policy responses. It shows that the three agencies adopted an all-inclusive approach to reduce conflicts, defend their legitimacy, and facilitate commitment for collaboration. Not only has this new framework reduced tensions between agencies, it has also reshaped the interests and interactions of other global actors. The case thus illustrates how these organisational actors actively manufacture new cognitive frames and policy regimes that advance their own legitimacy and influence. © 2012 The Author. Sociology of Health & Illness © 2012 Foundation for the Sociology of Health & Illness/Blackwell Publishing Ltd.

Student Agency and Language-Learning Processes and Outcomes in International Online Environments

ERIC Educational Resources Information Center

Basharina, Olga

2009-01-01

This research focuses on the kinds of learning afforded by asynchronous international computer-mediated communication (I-CMC) among Japanese, Mexican, and Russian English language learners and the role of student agency in learning. To find learning evidence, the discourse analysis and content analysis of interaction protocols were conducted in…

How To Adopt Internationally: A Guide for Agency-Directed and Independent Adoptions. 2000-2002 Edition.

ERIC Educational Resources Information Center

Nelson-Erichsen, Jean; Erichsen, Heino R.

Many potential adoptive parents seeking international adoption find the process to be extremely complex. This guide details the international adoption process, including organizing a home study and fulfilling state requirements as well as selecting a country from which to adopt, working through emigration and immigration agencies, and traveling…

76 FR 19740 - Notice of Public Information Collections Being Reviewed by the U.S. Agency for International...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-08

...;and investigations, committee meetings, agency decisions and rulings, #0;delegations of authority... Requested SUMMARY: U.S. Agency for International Development (USAID) is making efforts to reduce the... whether the information shall have practical utility; (b) the accuracy of the burden estimates; (c) ways...

77 FR 75105 - Notice of Public Information Collections Being Reviewed by the U.S. Agency for International...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-19

...;and investigations, committee meetings, agency decisions and rulings, #0;delegations of authority... Requested SUMMARY: U.S. Agency for International Development (USAID) is making efforts to reduce the... whether the information shall have practical utility; (b) the accuracy of the burden estimates; (c) ways...

Lobbying for international health: the link between good ideas and funded programs: Bread for the World and the Agency for International Development.

PubMed

Quinley, J C; Baker, T D

1986-07-01

Historically, the Agency for International Development (AIDS) health budget has been closely tied to overall development spending. A large increase in the international health appropriations in 1984 broke this pattern. Investigation shows that active grass roots organizing and congressional lobbying are the most likely responsible factors in the increase. Maintenance and expansion of this success will require increased recognition of and participation in these activities by individuals and organizations involved in international health.

Lobbying for international health: the link between good ideas and funded programs: Bread for the World and the Agency for International Development.

PubMed Central

Quinley, J C; Baker, T D

1986-01-01

Historically, the Agency for International Development (AIDS) health budget has been closely tied to overall development spending. A large increase in the international health appropriations in 1984 broke this pattern. Investigation shows that active grass roots organizing and congressional lobbying are the most likely responsible factors in the increase. Maintenance and expansion of this success will require increased recognition of and participation in these activities by individuals and organizations involved in international health. PMID:3717466

Pilot study of extremely low frequency magnetic fields emitted by transformers in dwellings. Social aspects.

PubMed

Zaryabova, Victoria; Shalamanova, Tsvetelina; Israel, Michel

2013-06-01

A large number of epidemiologic studies examining the potential effect of residential exposure to extremely-low frequency (ELF) magnetic fields and childhood leukemia have been published. Two pooled analyses [Ahlbom A, Day N, Feychting M, Roman E, Skinner J, Dockerty J, Linet M, et al. (2000). A pooled analysis of magnetic fields and childhood leukaemia. Br J Cancer. 83(5):692-698; Greenland S, Sheppard AR, Kaune WT, Poole C, Kelsh AM (2000). A pooled analysis of magnetic fields, wire codes, and childhood leukemia. Epidemiology. 11(6):624-634], which included the major epidemiologic studies on ELF magnetic fields and childhood leukemia showed twofold increase in childhood leukemia risk in association with residential ELF exposure above 0.3-0.4 μT. Based on "limited" epidemiologic evidence linking ELF exposure to childhood leukemia and "inadequate evidence" for carcinogenicity of ELF in rodent bioassays, the International Agency for Research on Cancer (IARC) classified ELF magnetic fields as a possible human carcinogen (2B classification) [International Agency for Research on Cancer (IARC) (2002). Non-ionizing radiation, Part 1: Static and extremely low-frequency (ELF) electric and magnetic fields. IARC monographs on the evaluation of carcinogenic risks to humans. Vol. 80. IARC Press: Lyon], confirmed by WHO on the basis of studies published after 2000 [World Health Organization. Extremely low frequency fields. In: 238 Environmental health criteria, Geneva: WHO; 2007]. The analysis of more recent studies of ELF magnetic fields and childhood leukemia had small findings and propose methodological improvements concerning the uncertainties in epidemiological approaches and exposure assessment, bias in selection of controls [Kheifets L, Oksuzyan S (2008). Exposure assessment and other challenges in non-ionizing radiation studies of childhood leukaemia. Radiat Prot Dosimetry. 132(2):139-147]. By the end of 2010, 37 countries had been identified for possible participation

Developing a Betel Quid Cessation Program on the Island of Guam.

PubMed

Moss, John; Kawamoto, Crissy; Pokhrel, Pallav; Paulino, Yvette; Herzog, Thaddeus

2015-01-01

Betel quid is a psychoactive drug preparation typically made up of a combination of areca quid, slaked lime, piper betel leaf and tobacco. It is the fourth most commonly consumed drug in the world with global use concentrated in the Asia-Pacific region (Boucher and Mannan, 2002; Warnakulasuriya and Peters, 2002). The International Agency for Research on Cancer has classified betel quid as a Group 1 carcinogen (IARC, 2004; Lin et al., 2006), and its use has been associated with oral and oropharyngeal cancer, oral lesions, oral leukoplakia, submucous fibrosis, gum disease, and cancer of the pharynx and esophagus (IARC, 2004; Oakley et al., 2005; Shah et al., 2002; Warnakulasuriya, 2002). This paper reports on the feasibility of an innovative betel quid cessation program carried on the U.S. territory of Guam, and is the first of its kind. The program is described, along with the challenges encountered during the implementation process.

Developing a Betel Quid Cessation Program on the Island of Guam

PubMed Central

Moss, John; Kawamoto, Crissy; Pokhrel, Pallav; Paulino, Yvette; Herzog, Thaddeus

2015-01-01

Betel quid is a psychoactive drug preparation typically made up of a combination of areca quid, slaked lime, piper betel leaf and tobacco. It is the fourth most commonly consumed drug in the world with global use concentrated in the Asia-Pacific region (Boucher and Mannan, 2002; Warnakulasuriya and Peters, 2002). The International Agency for Research on Cancer has classified betel quid as a Group 1 carcinogen (IARC, 2004; Lin et al., 2006), and its use has been associated with oral and oropharyngeal cancer, oral lesions, oral leukoplakia, submucous fibrosis, gum disease, and cancer of the pharynx and esophagus (IARC, 2004; Oakley et al., 2005; Shah et al., 2002; Warnakulasuriya, 2002). This paper reports on the feasibility of an innovative betel quid cessation program carried on the U.S. territory of Guam, and is the first of its kind. The program is described, along with the challenges encountered during the implementation process. PMID:27057560

Cancer surveillance in northern Africa, and central and western Asia: challenges and strategies in support of developing cancer registries.

PubMed

Znaor, Ariana; Eser, Sultan; Anton-Culver, Hoda; Fadhil, Ibtihal; Ryzhov, Anton; Silverman, Barbara G; Bendahou, Karima; Demetriou, Anna; Nimri, Omar; Yakut, Cankut; Bray, Freddie

2018-02-01

The Global Initiative for Cancer Registry Development partnership, led by the International Agency for Research on Cancer (IARC), was established in response to an overwhelming need for high-quality cancer incidence data from low-income and middle-income countries. The IARC Regional Hub for cancer registration in North Africa, Central and West Asia was founded in 2013 to support capacity building for cancer registration in each of the countries in this region. In this Series paper, we advocate the necessity for tailored approaches to cancer registration given the rapidly changing cancer landscape for this region, and the challenges faced at a national level in developing data systems to help support this process given present disparities in resources and health infrastructure. In addition, we provide an overview of the status of cancer surveillance and activities country-by-country, documenting tailored approaches that are informing local cancer-control policy, and potentially curbing the growing cancer burden across the region. Copyright © 2018 Elsevier Ltd. All rights reserved.

MATline: a job-exposure matrix for carcinogenic chemicals.

PubMed

Gilardi, Luisella; Falcone, Umberto; Santoro, Silvano; Coffano, Elena

2008-01-01

MATline is a tool that can be used to predict which industrial processes can be expected to involve the use of a substance that is considered carcinogenic as documented in the literature. The database includes agents carrying risk phrases R45, R49 and R40 according to the method of classification adopted by the EU and/or agents in categories 1, 2A and 2B as classified by the International Agency for Research on Cancer (IARC). Each agent is associated with a list of industrial processes coded according to the tariff headings used by the National Institute of Insurance against Occupational Injuries and Diseases (Istituto Nazionale per l'Assicurazione contro gli Infortuni sul Lavoro, INAIL). The main sources of information are the IARC Monographs and databases available through the National Library of Medicine's TOXNET portal. The matrix currently includes 600 carcinogenic agents, 23 classes of agents and some 7000 links between agents and industrial processes. MATline can be viewed on the www.dors.it website.

What Temperature of Coffee Exceeds the Pain Threshold? Pilot Study of a Sensory Analysis Method as Basis for Cancer Risk Assessment.

PubMed

Dirler, Julia; Winkler, Gertrud; Lachenmeier, Dirk W

2018-06-01

The International Agency for Research on Cancer (IARC) evaluates "very hot (>65 °C) beverages" as probably carcinogenic to humans. However, there is a lack of research regarding what temperatures consumers actually perceive as "very hot" or as "too hot". A method for sensory analysis of such threshold temperatures was developed. The participants were asked to mix a very hot coffee step by step into a cooler coffee. Because of that, the coffee to be tasted was incrementally increased in temperature during the test. The participants took a sip at every addition, until they perceive the beverage as too hot for consumption. The protocol was evaluated in the form of a pilot study using 87 participants. Interestingly, the average pain threshold of the test group (67 °C) and the preferred drinking temperature (63 °C) iterated around the IARC threshold for carcinogenicity. The developed methodology was found as fit for the purpose and may be applied in larger studies.

AID: The New Challenge. A Special Report of the Agency for International Development.

ERIC Educational Resources Information Center

Agency for International Development (Dept. of State), Washington, DC.

The programs and policies of the Agency for International Development (AID) in administering American foreign aid are briefly described in this booklet. Short introductory sections discuss the reasons for foreign aid, the interdependence of today's world, and the history of American foreign aid since World War II. The remaining parts of the…

32 CFR 2004.11 - Agency Implementing Regulations, Internal Rules, or Guidelines [102(b)(3)].

Code of Federal Regulations, 2014 CFR

2014-07-01

..., or Guidelines [102(b)(3)]. 2004.11 Section 2004.11 National Defense Other Regulations Relating to... NATIONAL INDUSTRIAL SECURITY PROGRAM DIRECTIVE NO. 1 Implementation and Oversight § 2004.11 Agency Implementing Regulations, Internal Rules, or Guidelines [102(b)(3)]. (a) Reviews and Updates. All implementing...

32 CFR 2004.11 - Agency Implementing Regulations, Internal Rules, or Guidelines [102(b)(3)].

Code of Federal Regulations, 2012 CFR

2012-07-01

..., or Guidelines [102(b)(3)]. 2004.11 Section 2004.11 National Defense Other Regulations Relating to... NATIONAL INDUSTRIAL SECURITY PROGRAM DIRECTIVE NO. 1 Implementation and Oversight § 2004.11 Agency Implementing Regulations, Internal Rules, or Guidelines [102(b)(3)]. (a) Reviews and Updates. All implementing...

32 CFR 2004.11 - Agency Implementing Regulations, Internal Rules, or Guidelines [102(b)(3)].

Code of Federal Regulations, 2013 CFR

2013-07-01

..., or Guidelines [102(b)(3)]. 2004.11 Section 2004.11 National Defense Other Regulations Relating to... NATIONAL INDUSTRIAL SECURITY PROGRAM DIRECTIVE NO. 1 Implementation and Oversight § 2004.11 Agency Implementing Regulations, Internal Rules, or Guidelines [102(b)(3)]. (a) Reviews and Updates. All implementing...

32 CFR 2004.11 - Agency Implementing Regulations, Internal Rules, or Guidelines [102(b)(3)].

Code of Federal Regulations, 2011 CFR

2011-07-01

..., or Guidelines [102(b)(3)]. 2004.11 Section 2004.11 National Defense Other Regulations Relating to... NATIONAL INDUSTRIAL SECURITY PROGRAM DIRECTIVE NO. 1 Implementation and Oversight § 2004.11 Agency Implementing Regulations, Internal Rules, or Guidelines [102(b)(3)]. (a) Reviews and Updates. All implementing...

[Biological effects of exposure to electromagnetic fields: introduction].

PubMed

Pira, E

2003-01-01

A widespread agreement on the presence, if any, of an association between non deterministic effects and exposure to electromagnetic fields (ELF and RF-MW) has not been reached yet. Some critical points of the pooled analyses of data that lead to the conclusion of the International Agency for Research on Cancer (IARC) are examined. While waiting for more well planned scientific studies, it seems important for scientific experts to give the most sober interpretation of current data, considering the widespread and growing attention of the general population for this subject.

Formaldehyde: a candidate toxic air contaminant. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Frye, B.; Parker, T.

1988-03-01

Formaldehyde (HCHO) is a gas widely used in adhesives and resins, textiles, embalming fluids, fungicides, air fresheners, and cosmetics. It is directly emitted into the ambient outdoor air from vehicular and stationary sources, and is also produced in the atmosphere from other substances by photochemical smog processes. The International Agency for Research on Cancer (IARC) has determined that there is sufficient evidence for carcinogenicity of formaldehyde to animals, and limited evidence for carcinogenicity to humans. EPA classifies formaldehyde as a probable human carcinogen with a one in a million risk concentration of 0.08 ppb.

Asphalt and risk of cancer in man.

PubMed Central

Chiazze, L; Watkins, D K; Amsel, J

1991-01-01

Epidemiological publications regarding the carcinogenic potential of asphalt (bitumen) are reviewed. In 1984 the International Agency for Research on Cancer (IARC) stated that there is "inadequate evidence that bitumens alone are carcinogenic to humans." They did, however, conclude that animal data provided sufficient evidence for the carcinogenicity of certain extracts of steam refined and air refined bitumens. In the absence of data on man, IARC considered it reasonable to regard chemicals with sufficient evidence of carcinogenicity in animals as if they presented a carcinogenic risk to man. Epidemiological data for man accumulated since the IARC report do not fulfil the criteria for showing a causal association between exposure to asphalt and development of cancer. The studies cited all suffer from a lack of data on exposure or potential confounders, which are necessary to establish whether or not such an association may or may not exist. In view of the evidence (or lack thereof) regarding asphalt today, an appropriate public health attitude suggests at least that action be taken to protect those working with asphalt by monitoring the workplace, taking whatever steps are possible to minimise exposures and to inform workers of potential hazards. At the same time, a need exists for well designed analytical epidemiological studies to determine whether a risk of cancer in man exists from exposure to asphalt. PMID:1878310

International Space Agency CIO Forum Industrial Control System (ICS) and Cyber

NASA Technical Reports Server (NTRS)

Powell, Robert

2017-01-01

This briefing covers Industrial Control System (ICS) best practices for enhancing cyber protection. The briefing provides a very high-level overview of best practices currently being pursued by NASA as well as by other US government agencies such as NIST and DHS ICS-CERT. All information presented in this slide deck is publicly available and no sensitive information is provided in these slides. These slides will be used to generate discussion around best practices within the international community in the area of ICS cyber protections.

International funding agencies: potential leaders of impact evaluation in protected areas?

PubMed Central

Craigie, Ian D.; Barnes, Megan D.; Geldmann, Jonas; Woodley, Stephen

2015-01-01

Globally, protected areas are the most commonly used tools to halt biodiversity loss. Yet, some are failing to adequately conserve the biodiversity they contain. There is an urgent need for knowledge on how to make them function more effectively. Impact evaluation methods provide a set of tools that could yield this knowledge. However, rigorous outcome-focused impact evaluation is not yet used as extensively as it could be in protected area management. We examine the role of international protected area funding agencies in facilitating the use of impact evaluation. These agencies are influential stakeholders as they allocate hundreds of millions of dollars annually to support protected areas, creating a unique opportunity to shape how the conservation funds are spent globally. We identify key barriers to the use of impact evaluation, detail how large funders are uniquely placed to overcome many of these, and highlight the potential benefits if impact evaluation is used more extensively. PMID:26460135

International funding agencies: potential leaders of impact evaluation in protected areas?

PubMed

Craigie, Ian D; Barnes, Megan D; Geldmann, Jonas; Woodley, Stephen

2015-11-05

Globally, protected areas are the most commonly used tools to halt biodiversity loss. Yet, some are failing to adequately conserve the biodiversity they contain. There is an urgent need for knowledge on how to make them function more effectively. Impact evaluation methods provide a set of tools that could yield this knowledge. However, rigorous outcome-focused impact evaluation is not yet used as extensively as it could be in protected area management. We examine the role of international protected area funding agencies in facilitating the use of impact evaluation. These agencies are influential stakeholders as they allocate hundreds of millions of dollars annually to support protected areas, creating a unique opportunity to shape how the conservation funds are spent globally. We identify key barriers to the use of impact evaluation, detail how large funders are uniquely placed to overcome many of these, and highlight the potential benefits if impact evaluation is used more extensively. © 2015 The Author(s).

Determining Nuclear Fingerprints: Glove Boxes, Radiation Protection, and the International Atomic Energy Agency.

PubMed

Rentetzi, Maria

2017-06-01

In a nuclear laboratory, a glove box is a windowed, sealed container equipped with two flexible gloves that allow the user to manipulate nuclear materials from the outside in an ostensibly safe environment. As a routine laboratory device, it invites neglect from historians and storytellers of science. Yet, since especially the Gulf War, glove boxes have put the interdependence of science, diplomacy, and politics into clear relief. Standing at the intersection of history of science and international history, technological materials and devices such as the glove box can provide penetrating insight into the role of international diplomatic organizations to the global circulation and control of scientific knowledge. The focus here is on the International Atomic Energy Agency. Copyright © 2017 The Author. Published by Elsevier Ltd.. All rights reserved.

International Atomic Energy Agency Bulletin, volume 22, no. 5 and 6

NASA Astrophysics Data System (ADS)

1980-10-01

The assessment of benefits and risks associated with various energy sources and systems is considered in relation to human needs. Particular emphasis is given to occupational hazards connected with coal mining, the handling of natural and liquified petroleum gases, and the use of nuclear energy for electric power generation. A method of energy risk comparison is examined as well as the approach of a regulatory agency to the concept of risk. Reports of international conferences on the management of alpha contaminated waste and on plasma physics and controlled nuclear fusion research are included.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Waters, M.D.; Stack, H.F.; Garrett, N.E.

A graphic approach, terms a Genetic Activity Profile (GAP), was developed to display a matrix of data on the genetic and related effects of selected chemical agents. The profiles provide a visual overview of the quantitative (doses) and qualitative (test results) data for each chemical. Either the lowest effective dose or highest ineffective dose is recorded for each agent and bioassay. Up to 200 different test systems are represented across the GAP. Bioassay systems are organized according to the phylogeny of the test organisms and the end points of genetic activity. The methodology for producing and evaluating genetic activity profilemore » was developed in collaboration with the International Agency for Research on Cancer (IARC). Data on individual chemicals were compiles by IARC and by the US Environmental Protection Agency (EPA). Data are available on 343 compounds selected from volumes 1-53 of the IARC Monographs and on 115 compounds identified as Superfund Priority Substances. Software to display the GAPs on an IBM-compatible personal computer is available from the authors. Structurally similar compounds frequently display qualitatively and quantitatively similar profiles of genetic activity. Through examination of the patterns of GAPs of pairs and groups of chemicals, it is possible to make more informed decisions regarding the selection of test batteries to be used in evaluation of chemical analogs. GAPs provided useful data for development of weight-of-evidence hazard ranking schemes. Also, some knowledge of the potential genetic activity of complex environmental mixtures may be gained from an assessment of the genetic activity profiles of component chemicals. The fundamental techniques and computer programs devised for the GAP database may be used to develop similar databases in other disciplines. 36 refs., 2 figs.« less

Preventable Exposures Associated With Human Cancers

PubMed Central

Baan, Robert; Straif, Kurt; Grosse, Yann; Lauby-Secretan, Béatrice; El Ghissassi, Fatiha; Bouvard, Véronique; Benbrahim-Tallaa, Lamia; Guha, Neela; Freeman, Crystal; Galichet, Laurent; Wild, Christopher P.

2011-01-01

Information on the causes of cancer at specific sites is important to cancer control planners, cancer researchers, cancer patients, and the general public. The International Agency for Research on Cancer (IARC) Monograph series, which has classified human carcinogens for more than 40 years, recently completed a review to provide up-to-date information on the cancer sites associated with more than 100 carcinogenic agents. Based on IARC’s review, we listed the cancer sites associated with each agent and then rearranged this information to list the known and suspected causes of cancer at each site. We also summarized the rationale for classifications that were based on mechanistic data. This information, based on the forthcoming IARC Monographs Volume 100, offers insights into the current state-of-the-science of carcinogen identification. Use of mechanistic data to identify carcinogens is increasing, and epidemiological research is identifying additional carcinogens and cancer sites or confirming carcinogenic potential under conditions of lower exposure. Nevertheless, some common human cancers still have few (or no) identified causal agents. PMID:22158127

The suitability of using death certificates as a data source for cancer mortality assessment in Turkey

PubMed Central

Ulus, Tumer; Yurtseven, Eray; Cavdar, Sabanur; Erginoz, Ethem; Erdogan, M. Sarper

2012-01-01

Aim To compare the quality of the 2008 cancer mortality data of the Istanbul Directorate of Cemeteries (IDC) with the 2008 data of International Agency for Research on Cancer (IARC) and Turkish Statistical Institute (TUIK), and discuss the suitability of using this databank for estimations of cancer mortality in the future. Methods We used 2008 and 2010 death records of the IDC and compared it to TUIK and IARC data. Results According to the WHO statistics, in Turkey in 2008 there were 67 255 estimated cancer deaths. As the population of Turkey was 71 517 100, the cancer mortality rate was 9.4 per 10 000. According to the IDC statistics, the cancer mortality rate in Istanbul in 2008 was 5.97 per 10 000. Conclusion IDC estimates were higher than WHO estimates probably because WHO bases its estimates on a sample group and because of the restrictions of IDC data collection method. Death certificates could be a reliable and accurate data source for mortality statistics if the problems of data collection are solved. PMID:23100210

Effectiveness of tax and price policies in tobacco control.

PubMed

Chaloupka, Frank J; Straif, Kurt; Leon, Maria E

2011-05-01

Over 20 experts on economics, epidemiology, public policy and tobacco control were asked by the International Agency for Research on Cancer (IARC) to evaluate the strength of the available evidence on the effects of tax and price policies to prevent and reduce tobacco use. Draft papers presenting and assessing the evidence on the following topics were developed by the experts in an 8-month period prior to the meeting: tobacco industry pricing strategies and tax related lobbying; tax, price and aggregate demand for tobacco; tax, price and adult tobacco use, use among young people and use among the poor; tax avoidance and tax evasion; and the economic and health impact of tobacco taxation. Subsequently, papers were peer reviewed, revised and resubmitted for final discussion at a 6-day meeting at IARC in Lyon, France, where a consensus evaluation of 18 concluding statements using the pre-established criteria of the IARC Cancer Prevention Handbooks took place. Studies published (or accepted for publication) in the openly available scientific literature were the main source of evidence for the review and evaluation; other types of publications were included when appropriate. In support of 12 of the 18 conclusions, the experts agreed that there was sufficient evidence of effectiveness of increased tobacco excise taxes and prices in reducing overall tobacco consumption and prevalence of tobacco use and improvement of public health, including by preventing initiation and uptake among young people, promoting cessation among current users and lowering consumption among those who continue to use. For the remaining six concluding statements the evidence was strong (four statements) or limited (two statements). The evidence presented and assessed in IARC Handbook volume 14 documents the effectiveness of tax and price policies in the control of tobacco use and improvement of public health.

Trichloroethylene: Mechanistic, epidemiologic and other supporting evidence of carcinogenic hazard.

PubMed

Rusyn, Ivan; Chiu, Weihsueh A; Lash, Lawrence H; Kromhout, Hans; Hansen, Johnni; Guyton, Kathryn Z

2014-01-01

The chlorinated solvent trichloroethylene (TCE) is a ubiquitous environmental pollutant. The carcinogenic hazard of TCE was the subject of a 2012 evaluation by a Working Group of the International Agency for Research on Cancer (IARC). Information on exposures, relevant data from epidemiologic studies, bioassays in experimental animals, and toxicity and mechanism of action studies was used to conclude that TCE is carcinogenic to humans (Group 1). This article summarizes the key evidence forming the scientific bases for the IARC classification. Exposure to TCE from environmental sources (including hazardous waste sites and contaminated water) is common throughout the world. While workplace use of TCE has been declining, occupational exposures remain of concern, especially in developing countries. The strongest human evidence is from studies of occupational TCE exposure and kidney cancer. Positive, although less consistent, associations were reported for liver cancer and non-Hodgkin lymphoma. TCE is carcinogenic at multiple sites in multiple species and strains of experimental animals. The mechanistic evidence includes extensive data on the toxicokinetics and genotoxicity of TCE and its metabolites. Together, available evidence provided a cohesive database supporting the human cancer hazard of TCE, particularly in the kidney. For other target sites of carcinogenicity, mechanistic and other data were found to be more limited. Important sources of susceptibility to TCE toxicity and carcinogenicity were also reviewed by the Working Group. In all, consideration of the multiple evidence streams presented herein informed the IARC conclusions regarding the carcinogenicity of TCE. © 2013.

Trichloroethylene: Mechanistic, Epidemiologic and Other Supporting Evidence of Carcinogenic Hazard

PubMed Central

Rusyn, Ivan; Chiu, Weihsueh A.; Lash, Lawrence H.; Kromhout, Hans; Hansen, Johnni; Guyton, Kathryn Z.

2013-01-01

The chlorinated solvent trichloroethylene (TCE) is a ubiquitous environmental pollutant. The carcinogenic hazard of TCE was the subject of a 2012 evaluation by a Working Group of the International Agency for Research on Cancer (IARC). Information on exposures, relevant data from epidemiologic studies, bioassays in experimental animals, and toxicity and mechanism of action studies was used to conclude that TCE is carcinogenic to humans (Group 1). This article summarizes the key evidence forming the scientific bases for the IARC classification. Exposure to TCE from environmental sources (including from hazardous waste sites and contaminated water) is common throughout the world. While workplace use of TCE has been declining, occupational exposures remain of concern, especially in developing countries. Strongest human evidence is from studies of occupational TCE exposure and kidney cancer. Positive, although less consistent, associations were reported for liver cancer and non-Hodgkin's lymphoma. TCE is carcinogenic at multiple sites in multiple species and strains of experimental animals. The mechanistic evidence includes extensive data on the toxicokinetics and genotoxicity of TCE and its metabolites. Together, available evidence provided a cohesive database supporting the human cancer hazard of TCE, particularly in the kidney. For other target sites of carcinogenicity, mechanistic and other data were found to be more limited. Important sources of susceptibility to TCE toxicity and carcinogenicity were also reviewed by the Working Group. In all, consideration of the multiple evidence streams presented herein informed the IARC conclusions regarding the carcinogenicity of TCE. PMID:23973663

How research funding agencies support science integration into policy and practice: an international overview.

PubMed

Smits, Pernelle A; Denis, Jean-Louis

2014-02-24

Funding agencies constitute one essential pillar for policy makers, researchers and health service delivery institutions. Such agencies are increasingly providing support for science implementation. In this paper, we investigate health research funding agencies and how they support the integration of science into policy, and of science into practice, and vice versa. We selected six countries: Australia, The Netherlands, France, Canada, England and the United States. For 13 funding agencies, we compared their intentions to support, their actions related to science integration into policy and practice, and the reported benefits of this integration. We did a qualitative content analysis of the reports and information provided on the funding agencies' websites. Most funding agencies emphasized the importance of science integration into policy and practice in their strategic orientation, and stated how this integration was structured. Their funding activities were embedded in the push, pull, or linkage/exchange knowledge transfer model. However, few program funding efforts were based on all three models. The agencies reported more often on the benefits of integration on practice, rather than on policy. External programs that were funded largely covered science integration into policy and practice at the end of grant stage, while overlooking the initial stages. Finally, external funding actions were more prominent than internally initiated bridging activities and training activities on such integration. This paper contributes to research on science implementation because it goes beyond the two community model of researchers versus end users, to include funding agencies. Users of knowledge may be end users in health organizations like hospitals; civil servants assigned to decision making positions within funding agencies; civil servants outside of the Ministry of Health, such as the Ministry of the Environment; politicians deciding on health-related legislation; or even

Parasite-Associated Cancers (Blood Flukes/Liver Flukes).

PubMed

Feng, Meng; Cheng, Xunjia

2017-01-01

Parasitic infection remains as a persistent public health problem and can be carcinogenic. Three helminth parasites, namely, Clonorchis sinensis (liver fluke) and Opisthorchis viverrini as well as Schistosoma haematobium (blood fluke), are classified as Group 1 carcinogens by the World Health Organization's International Agency for Research on Cancer (IARC Infection with liver flukes (Opisthorchis viverrini, Opisthorchis felineus and Clonorchis sinensis), World Health Organization, International Agency for Research on Cancer, 2011). Infection by these parasites is frequently asymptomatic and is thus rarely diagnosed at early exposure. Persistent infection can cause severe cancer complications. Until now, the cellular and molecular mechanisms linking fluke infections to cancer formation have yet to be defined, although many studies have focused on these mechanisms in recent years, and numerous findings were made in various aspects of parasite-associated cancers. Herein, we only introduce the fluke-induced cholangiocarcinoma (CCA) and bladder carcinoma and mainly focus on key findings in the last 5 years.

The AACRAO-AID Participant Selection and Placement Study. Report to the Office of International Training, Agency for International Development, U. S. Department of State.

ERIC Educational Resources Information Center

Bower, James R.; And Others

The U. S. Agency for International Development (AID) contracted with the American Association of Collegiate Registrars and Admissions Officers (AACRAO) to provide professional consultant services and academic credential analysts to improve the selection and admission of AID-sponsored participants (foreign students) for study in U. S. academic…

How research funding agencies support science integration into policy and practice: An international overview

PubMed Central

2014-01-01

Background Funding agencies constitute one essential pillar for policy makers, researchers and health service delivery institutions. Such agencies are increasingly providing support for science implementation. In this paper, we investigate health research funding agencies and how they support the integration of science into policy, and of science into practice, and vice versa. Methods We selected six countries: Australia, The Netherlands, France, Canada, England and the United States. For 13 funding agencies, we compared their intentions to support, their actions related to science integration into policy and practice, and the reported benefits of this integration. We did a qualitative content analysis of the reports and information provided on the funding agencies’ websites. Results Most funding agencies emphasized the importance of science integration into policy and practice in their strategic orientation, and stated how this integration was structured. Their funding activities were embedded in the push, pull, or linkage/exchange knowledge transfer model. However, few program funding efforts were based on all three models. The agencies reported more often on the benefits of integration on practice, rather than on policy. External programs that were funded largely covered science integration into policy and practice at the end of grant stage, while overlooking the initial stages. Finally, external funding actions were more prominent than internally initiated bridging activities and training activities on such integration. Conclusions This paper contributes to research on science implementation because it goes beyond the two community model of researchers versus end users, to include funding agencies. Users of knowledge may be end users in health organizations like hospitals; civil servants assigned to decision making positions within funding agencies; civil servants outside of the Ministry of Health, such as the Ministry of the Environment; politicians deciding

Concern that "EMF" magnetic fields from power lines cause cancer.

PubMed

Repacholi, Michael

2012-06-01

In 2002, the International Agency for Research on Cancer (IARC, 2002) categorized extremely low frequency (ELF) (including the power frequencies of 50 and 60 Hz) magnetic fields as "possibly carcinogenic to humans." That was based on pooled analyses of epidemiological research that reported an association between exposure to low-level magnetic fields and childhood leukemia. In 2007 a task group of scientific experts convened by the World Health Organization (WHO) acknowledged the IARC categorization but found that the laboratory studies and other research results did not support the association. Taking all evidence into account WHO reported that it could not confirm the existence of any health consequences from exposure to low-level magnetic fields. There remains continuing concern by some people that exposure to power frequency magnetic fields may cause adverse health effects, particularly childhood leukemia. Public health authorities need to fully understand the reasons for that ongoing concern and effective ways to address it. This paper describes what drives the concern, including how people perceive risks, how WHO and other public health authorities assess scientific research to determine whether health risks exist and the conclusions they have reached about power frequency magnetic fields. This paper also addresses the scientific basis of international exposure guidelines for power frequency magnetic fields and what precautionary measures are warranted to address the concern. Copyright © 2012. Published by Elsevier B.V.

Defense Contract Management Agency

Science.gov Websites

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Battered Agency Syndrome: The Challenge to Agencies Serving Low-Income Communities.

ERIC Educational Resources Information Center

Reed, Diane; Lally, J. Ronald; Quiett, Douglas

Community-based social service agencies working in low-income communities increasingly function with inadequate support and encounter numerous oppressive external and internal conditions that compromise organizational and staff well-being. Working with many such agencies, WestEd identified stressors that included funding problems, unrealistic…

International Energy Agency Ocean Energy Systems Task 10 Wave Energy Converter Modeling Verification and Validation: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wendt, Fabian F; Yu, Yi-Hsiang; Nielsen, Kim

This is the first joint reference paper for the Ocean Energy Systems (OES) Task 10 Wave Energy Converter modeling verification and validation group. The group is established under the OES Energy Technology Network program under the International Energy Agency. OES was founded in 2001 and Task 10 was proposed by Bob Thresher (National Renewable Energy Laboratory) in 2015 and approved by the OES Executive Committee EXCO in 2016. The kickoff workshop took place in September 2016, wherein the initial baseline task was defined. Experience from similar offshore wind validation/verification projects (OC3-OC5 conducted within the International Energy Agency Wind Task 30)more » [1], [2] showed that a simple test case would help the initial cooperation to present results in a comparable way. A heaving sphere was chosen as the first test case. The team of project participants simulated different numerical experiments, such as heave decay tests and regular and irregular wave cases. The simulation results are presented and discussed in this paper.« less

Comparison between carcinogenicity and mutagenicity based on chemicals evaluated in the IARC monographs.

PubMed Central

Bartsch, H; Tomatis, L

1983-01-01

The qualitative relationship between carcinogenicity and mutagenicity (DNA-damaging activity), based on chemicals which are known to be or suspected of being carcinogenic to man and/or to experimental animals, is analyzed using 532 chemicals evaluated in Volumes 1-25 of the IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. About 40 compounds (industrial processes) were found to be either definitely or probably carcinogenic to man, and 130 chemicals have been adequately tested in rodents and most of them also in various short-term assays. For a comparison between the carcinogenicity of a chemical and its behavior in short-term tests, systems were selected that have a value for predicting carcinogenicity. These were divided into mutagenicity in (A) the S. typhimurium/microsome assay, (B) other submammalian systems and (C) cultured mammalian cells; (D) chromosomal abnormalities in mammalian cells; (E) DNA damage and repair; (F) cell transformation (or altered growth properties) in vitro. The following conclusions can be drawn. In the absence of studies in man, long-term animal tests are still today the only ones capable of providing evidence of the carcinogenic effect of a chemical. The development and application of an appropriate combination of short-term tests (despite current limitations) can significantly contribute to the prediction/confirmation of the carcinogenic effects of chemicals in animals/man. Confidence in positive tests results is increased when they are confirmed in multiple short-term tests using nonrepetitive end points and different activation systems. Assays to detect carcinogens which do not act via electrophiles (promoters) need to be developed. The results of a given short-term test should be interpreted in the context of other toxicological data. Increasing demand for quantitative carcinogenicity data requires further examination of whether or not there is a quantitative relationship between the potency of a

48 CFR 715.604 - Agency points of contact.

Code of Federal Regulations, 2011 CFR

2011-10-01

.... 715.604 Section 715.604 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Unsolicited Proposals 715.604 Agency points... the U.S. Agency for International Development, Evaluation Division, Room 7.08-005, 1300 Pennsylvania...

When Work is Related to Disease, What Establishes Evidence for a Causal Relation?

PubMed

Verbeek, Jos

2012-06-01

Establishing a causal relationship between factors at work and disease is difficult for occupational physicians and researchers. This paper seeks to provide arguments for the judgement of evidence of causality in observational studies that relate work factors to disease. I derived criteria for the judgement of evidence of causality from the following sources: the criteria list of Hill, the approach by Rothman, the methods used by International Agency for Research on Cancer (IARC), and methods used by epidemiologists. The criteria are applied to two cases of putative occupational diseases; breast cancer caused by shift work and aerotoxic syndrome. Only three of the Hill criteria can be applied to an actual study. Rothman stresses the importance of confounding and alternative explanations than the putative cause. IARC closely follows Hill, but they also incorporate other than epidemiological evidence. Applied to shift work and breast cancer, these results have found moderate evidence for a causal relationship, but applied to the aerotoxic syndrome, there is an absence of evidence of causality. There are no ready to use algorithms for judgement of evidence of causality. Criteria from different sources lead to similar results and can make a conclusion of causality more or less likely.

Historical review of the causes of cancer

PubMed Central

Blackadar, Clarke Brian

2016-01-01

In the early 1900s, numerous seminal publications reported that high rates of cancer occurred in certain occupations. During this period, work with infectious agents produced only meager results which seemed irrelevant to humans. Then in the 1980s ground breaking evidence began to emerge that a variety of viruses also cause cancer in humans. There is now sufficient evidence of carcinogenicity in humans for human T-cell lymphotrophic virus, human immunodeficiency virus, hepatitis B virus, hepatitis C virus, human papillomavirus, Epstein-Barr virus, and human herpes virus 8 according to the International Agency for Research on Cancer (IARC). Many other causes of cancer have also been identified by the IARC, which include: Sunlight, tobacco, pharmaceuticals, hormones, alcohol, parasites, fungi, bacteria, salted fish, wood dust, and herbs. The World Cancer Research Fund and the American Institute for Cancer Research have determined additional causes of cancer, which include beta carotene, red meat, processed meats, low fibre diets, not breast feeding, obesity, increased adult height and sedentary lifestyles. In brief, a historical review of the discoveries of the causes of human cancer is presented with extended discussions of the difficulties encountered in identifying viral causes of cancer. PMID:26862491

Historical review of the causes of cancer.

PubMed

Blackadar, Clarke Brian

2016-02-10

In the early 1900s, numerous seminal publications reported that high rates of cancer occurred in certain occupations. During this period, work with infectious agents produced only meager results which seemed irrelevant to humans. Then in the 1980s ground breaking evidence began to emerge that a variety of viruses also cause cancer in humans. There is now sufficient evidence of carcinogenicity in humans for human T-cell lymphotrophic virus, human immunodeficiency virus, hepatitis B virus, hepatitis C virus, human papillomavirus, Epstein-Barr virus, and human herpes virus 8 according to the International Agency for Research on Cancer (IARC). Many other causes of cancer have also been identified by the IARC, which include: Sunlight, tobacco, pharmaceuticals, hormones, alcohol, parasites, fungi, bacteria, salted fish, wood dust, and herbs. The World Cancer Research Fund and the American Institute for Cancer Research have determined additional causes of cancer, which include beta carotene, red meat, processed meats, low fibre diets, not breast feeding, obesity, increased adult height and sedentary lifestyles. In brief, a historical review of the discoveries of the causes of human cancer is presented with extended discussions of the difficulties encountered in identifying viral causes of cancer.

Unconventional oil and gas development and risk of childhood leukemia: Assessing the evidence.

PubMed

Elliott, Elise G; Trinh, Pauline; Ma, Xiaomei; Leaderer, Brian P; Ward, Mary H; Deziel, Nicole C

2017-01-15

The widespread distribution of unconventional oil and gas (UO&G) wells and other facilities in the United States potentially exposes millions of people to air and water pollutants, including known or suspected carcinogens. Childhood leukemia is a particular concern because of the disease severity, vulnerable population, and short disease latency. A comprehensive review of carcinogens and leukemogens associated with UO&G development is not available and could inform future exposure monitoring studies and human health assessments. The objective of this analysis was to assess the evidence of carcinogenicity of water contaminants and air pollutants related to UO&G development. We obtained a list of 1177 chemicals in hydraulic fracturing fluids and wastewater from the U.S. Environmental Protection Agency and constructed a list of 143 UO&G-related air pollutants through a review of scientific papers published through 2015 using PubMed and ProQuest databases. We assessed carcinogenicity and evidence of increased risk for leukemia/lymphoma of these chemicals using International Agency for Research on Cancer (IARC) monographs. The majority of compounds (>80%) were not evaluated by IARC and therefore could not be reviewed. Of the 111 potential water contaminants and 29 potential air pollutants evaluated by IARC (119 unique compounds), 49 water and 20 air pollutants were known, probable, or possible human carcinogens (55 unique compounds). A total of 17 water and 11 air pollutants (20 unique compounds) had evidence of increased risk for leukemia/lymphoma, including benzene, 1,3-butadiene, cadmium, diesel exhaust, and several polycyclic aromatic hydrocarbons. Though information on the carcinogenicity of compounds associated with UO&G development was limited, our assessment identified 20 known or suspected carcinogens that could be measured in future studies to advance exposure and risk assessments of cancer-causing agents. Our findings support the need for investigation into

Population-based programs for increasing colorectal cancer screening in the United States.

PubMed

Verma, Manisha; Sarfaty, Mona; Brooks, Durado; Wender, Richard C

2015-01-01

Answer questions and earn CME/CNE Screening to detect polyps or cancer at an early stage has been shown to produce better outcomes in colorectal cancer (CRC). Programs with a population-based approach can reach a large majority of the eligible population and can offer cost-effective interventions with the potential benefit of maximizing early cancer detection and prevention using a complete follow-up plan. The purpose of this review was to summarize the key features of population-based programs to increase CRC screening in the United States. A search was conducted in the SCOPUS, OvidSP, and PubMed databases. The authors selected published reports of population-based programs that met at least 5 of the 6 International Agency for Research on Cancer (IARC) criteria for cancer prevention and were known to the National Colorectal Cancer Roundtable. Interventions at the level of individual practices were not included in this review. IARC cancer prevention criteria served as a framework to assess the effective processes and elements of a population-based program. Eight programs were included in this review. Half of the programs met all IARC criteria, and all programs led to improvements in screening rates. The rate of colonoscopy after a positive stool test was heterogeneous among programs. Different population-based strategies were used to promote these screening programs, including system-based, provider-based, patient-based, and media-based strategies. Treatment of identified cancer cases was not included explicitly in 4 programs but was offered through routine medical care. Evidence-based methods for promoting CRC screening at a population level can guide the development of future approaches in health care prevention. The key elements of a successful population-based approach include adherence to the 6 IARC criteria and 4 additional elements (an identified external funding source, a structured policy for positive fecal occult blood test results and confirmed cancer

International Energy Agency (IEA): Implementing Agreement for Co-operation in the Research and Development of Wind Turbine Systems (IEA Wind)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sinclair, Karin C

This fact sheet covers the work that is being done via the International Energy Agency Task 34 (WREN). The fact sheet highlights the objective, strategy, primary activities, members, and contacts for this task.

76 FR 40773 - Agency Information Collection Activity; Proposed Collection

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77 FR 4404 - Agency Information Collection Activity; Proposed Collection

Federal Register 2010, 2011, 2012, 2013, 2014

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European Code against Cancer 4th Edition: Alcohol drinking and cancer.

PubMed

Scoccianti, Chiara; Cecchini, Michele; Anderson, Annie S; Berrino, Franco; Boutron-Ruault, Marie-Christine; Espina, Carolina; Key, Timothy J; Leitzmann, Michael; Norat, Teresa; Powers, Hilary; Wiseman, Martin; Romieu, Isabelle

2016-12-01

Alcohol consumption is the third leading risk factor for disease and mortality in Europe. As evaluated by the International Agency for Research on Cancer (IARC) Monographs, a causal relationship is established for consumption of alcoholic beverages and cancers of the oral cavity, pharynx, larynx, oesophagus, liver, colorectum and female breast, even at low and moderate alcohol intakes. The higher the amount of alcohol consumed, the higher the risk of developing cancer. In Europe, an estimated 10% (95% CI: 7%-13%) of all cancer cases in men and 3% (95% CI: 1%-5%) of all cancer cases in women are attributable to alcohol consumption. Several biological mechanisms explain the carcinogenicity of alcohol; among them, ethanol and its genotoxic metabolite, acetaldehyde, play a major role. Taking all this evidence into account, a recommendation of the 4th edition of European Code against Cancer is: "If you drink alcohol of any type, limit your intake. Not drinking alcohol is better for cancer prevention." Copyright © 2016 International Agency for Research on Cancer. Published by Elsevier Ltd.. All rights reserved.

48 CFR 702.170-6 - Executive agency.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Executive agency. 702.170-6 Section 702.170-6 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL DEFINITIONS OF WORDS AND TERMS Definitions 702.170-6 Executive agency. Executive agency includes...

22 CFR 214.43 - Agency records.

Code of Federal Regulations, 2010 CFR

2010-04-01

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76 FR 1523 - New Agency Logos

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2011-01-11

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2010-01-01

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75 FR 51388 - 2-methyl-1,3-propanediol; Exemption from the Requirement of a Tolerance

Federal Register 2010, 2011, 2012, 2013, 2014

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... mutagenic in an in vitro chromosome aberration test, bacterial gene mutation test, and mammalian cell gene... Research on Cancer (IARC). Based on available studies, there is no evidence of genotoxic activity. There is... hazard endpoint, the Agency has determined that a quantitative risk assessment using safety factors...

Alternate Funding Sources for the International Atomic Energy Agency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Toomey, Christopher; Wyse, Evan T.; Kurzrok, Andrew J.

Since 1957, the International Atomic Energy Agency (IAEA) has worked to ensure the safe and responsible promotion of nuclear technology throughout the world. The IAEA operates at the intersection of the Nuclear Nonproliferation Treaty’s (NPT) fourth and third articles, which guarantee Parties to the Treaty the right to peaceful uses of nuclear technology, provided those activities are placed under safeguards verified by the IAEA. However, while the IAEA has enjoyed substantial success and prestige in the international community, there is a concern that its resources are being stretched to a point where it may no longer be possible to executemore » its multifaceted mission in its entirety. As noted by the Director General (DG) in 2008, demographics suggest that every aspect of the IAEA’s operations will be in higher demand due to increasing reliance on non-carbon-based energy and the concomitant nonproliferation, safety, and security risks that growth entails. In addition to these nuclear energy concerns, the demand for technical developmental assistance in the fields of food security, resource conservation, and human health is also predicted to increase as the rest of the world develops. Even with a 100% value-for-money rating by the U.S. Office of Management and Budget (OMB) and being described as an “extraordinary bargain” by the United Nations Secretary-General’s High-level Panel on Threats, Challenges and Change, real budget growth at the Agency has been limited to zero-real growth for a better part of the last two decades. Although the 2012 regular budget (RB) received a small increase for most programs, the 2013 RB has been set at zero-real growth. As a result, the IAEA has had to defer infrastructure investments, which has hindered its ability to provide the public goods its Members seek, decreased global security and development opportunities, and functionally transformed the IAEA into a charity, dependent on extrabudgetary (EB) contributions to

Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis

PubMed Central

Smith, Martyn T.; Guyton, Kathryn Z.; Gibbons, Catherine F.; Fritz, Jason M.; Portier, Christopher J.; Rusyn, Ivan; DeMarini, David M.; Caldwell, Jane C.; Kavlock, Robert J.; Lambert, Paul F.; Hecht, Stephen S.; Bucher, John R.; Stewart, Bernard W.; Baan, Robert A.; Cogliano, Vincent J.; Straif, Kurt

2015-01-01

Background: A recent review by the International Agency for Research on Cancer (IARC) updated the assessments of the > 100 agents classified as Group 1, carcinogenic to humans (IARC Monographs Volume 100, parts A–F). This exercise was complicated by the absence of a broadly accepted, systematic method for evaluating mechanistic data to support conclusions regarding human hazard from exposure to carcinogens. Objectives and Methods: IARC therefore convened two workshops in which an international Working Group of experts identified 10 key characteristics, one or more of which are commonly exhibited by established human carcinogens. Discussion: These characteristics provide the basis for an objective approach to identifying and organizing results from pertinent mechanistic studies. The 10 characteristics are the abilities of an agent to 1) act as an electrophile either directly or after metabolic activation; 2) be genotoxic; 3) alter DNA repair or cause genomic instability; 4) induce epigenetic alterations; 5) induce oxidative stress; 6) induce chronic inflammation; 7) be immunosuppressive; 8) modulate receptor-mediated effects; 9) cause immortalization; and 10) alter cell proliferation, cell death, or nutrient supply. Conclusion: We describe the use of the 10 key characteristics to conduct a systematic literature search focused on relevant end points and construct a graphical representation of the identified mechanistic information. Next, we use benzene and polychlorinated biphenyls as examples to illustrate how this approach may work in practice. The approach described is similar in many respects to those currently being implemented by the U.S. EPA’s Integrated Risk Information System Program and the U.S. National Toxicology Program. Citation: Smith MT, Guyton KZ, Gibbons CF, Fritz JM, Portier CJ, Rusyn I, DeMarini DM, Caldwell JC, Kavlock RJ, Lambert P, Hecht SS, Bucher JR, Stewart BW, Baan R, Cogliano VJ, Straif K. 2016. Key characteristics of carcinogens as a

Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis.

PubMed

Smith, Martyn T; Guyton, Kathryn Z; Gibbons, Catherine F; Fritz, Jason M; Portier, Christopher J; Rusyn, Ivan; DeMarini, David M; Caldwell, Jane C; Kavlock, Robert J; Lambert, Paul F; Hecht, Stephen S; Bucher, John R; Stewart, Bernard W; Baan, Robert A; Cogliano, Vincent J; Straif, Kurt

2016-06-01

A recent review by the International Agency for Research on Cancer (IARC) updated the assessments of the > 100 agents classified as Group 1, carcinogenic to humans (IARC Monographs Volume 100, parts A-F). This exercise was complicated by the absence of a broadly accepted, systematic method for evaluating mechanistic data to support conclusions regarding human hazard from exposure to carcinogens. IARC therefore convened two workshops in which an international Working Group of experts identified 10 key characteristics, one or more of which are commonly exhibited by established human carcinogens. These characteristics provide the basis for an objective approach to identifying and organizing results from pertinent mechanistic studies. The 10 characteristics are the abilities of an agent to 1) act as an electrophile either directly or after metabolic activation; 2) be genotoxic; 3) alter DNA repair or cause genomic instability; 4) induce epigenetic alterations; 5) induce oxidative stress; 6) induce chronic inflammation; 7) be immunosuppressive; 8) modulate receptor-mediated effects; 9) cause immortalization; and 10) alter cell proliferation, cell death, or nutrient supply. We describe the use of the 10 key characteristics to conduct a systematic literature search focused on relevant end points and construct a graphical representation of the identified mechanistic information. Next, we use benzene and polychlorinated biphenyls as examples to illustrate how this approach may work in practice. The approach described is similar in many respects to those currently being implemented by the U.S. EPA's Integrated Risk Information System Program and the U.S. National Toxicology Program. Smith MT, Guyton KZ, Gibbons CF, Fritz JM, Portier CJ, Rusyn I, DeMarini DM, Caldwell JC, Kavlock RJ, Lambert P, Hecht SS, Bucher JR, Stewart BW, Baan R, Cogliano VJ, Straif K. 2016. Key characteristics of carcinogens as a basis for organizing data on mechanisms of carcinogenesis. Environ Health

Vital pulpotomy in the primary dentition: attitudes and practices of community dental staff in Wales.

PubMed

Hingston, Emma Jane; Parmar, Sharlene; Hunter, Margaret Lindsay

2007-05-01

The International Agency for Research on Cancer (IARC) has classified formaldehyde as carcinogenic to humans, leaving the dental profession to look for viable substitutes to formocresol in the vital pulpotomy technique. This study was designed to examine the attitudes and practices of Community Dental Service (CDS) staff in Wales in relation to vital pulpotomy for primary molars 18 months following the IARC's press release. The study employed a postal questionnaire. Questionnaires were returned by 79 (78.2%) of the CDS staff surveyed, yielding a sample of 65 dentists practising the technique. The most commonly used pulpotomy agents were formocresol, paraformaldehyde and ferric sulphate. Twenty-seven (41.5%) dentists expressed concern regarding their preferred pulpotomy agent and 17 (26.2%) were considering changing their technique. Only one respondent (1.5% of the sample) routinely took preoperative radiographs; follow-up radiographs were routinely taken by only three dentists (4.6%). Only 44 respondents (67.7%) always used local anaesthesia for this form of treatment. Amalgam was the most commonly used restorative material. Twenty-two respondents (33.8%) stated that they would pulp treat a primary molar on more than one occasion. The results of this study suggest that there is need for relevant continuing professional development courses for CDS staff in Wales.

When Work is Related to Disease, What Establishes Evidence for a Causal Relation?

PubMed Central

2012-01-01

Establishing a causal relationship between factors at work and disease is difficult for occupational physicians and researchers. This paper seeks to provide arguments for the judgement of evidence of causality in observational studies that relate work factors to disease. I derived criteria for the judgement of evidence of causality from the following sources: the criteria list of Hill, the approach by Rothman, the methods used by International Agency for Research on Cancer (IARC), and methods used by epidemiologists. The criteria are applied to two cases of putative occupational diseases; breast cancer caused by shift work and aerotoxic syndrome. Only three of the Hill criteria can be applied to an actual study. Rothman stresses the importance of confounding and alternative explanations than the putative cause. IARC closely follows Hill, but they also incorporate other than epidemiological evidence. Applied to shift work and breast cancer, these results have found moderate evidence for a causal relationship, but applied to the aerotoxic syndrome, there is an absence of evidence of causality. There are no ready to use algorithms for judgement of evidence of causality. Criteria from different sources lead to similar results and can make a conclusion of causality more or less likely. PMID:22993715

The contribution of molecular epidemiology to the identification of human carcinogens: current status and future perspectives.

PubMed

Boffetta, P; Islami, F

2013-04-01

The use of biological-based markers of exposure, intermediate effect, outcome, and susceptibility has become standard practice in cancer epidemiology, which has contributed to identification of several carcinogenic agents. Nevertheless, with the exception of biological agents, this contribution, in terms of providing sufficiently strong evidence as required by the International Agency for Research on Cancer (IARC) monographs, has been modest. We discuss the overall contribution of molecular epidemiology to identification of carcinogens, with focus on IARC monographs. For many carcinogens, valid biological markers of exposure and mechanisms of actions are not available. Molecular markers are usually assessed in single biological samples, which may not represent the actual exposure or biological events related to carcinogens. The contribution of molecular epidemiology to identification of carcinogens has mainly been limited to the carcinogens acting through a genotoxic mechanism, i.e. when carcinogens induce DNA damage. A number of factors, including certain hormones and overweight/obesity, may show carcinogenic effects through nongenotoxic pathways, for which mechanisms of carcinogenicity are not well identified and their biomarkers are sparse. Longitudinal assessment of biomarkers may provide more informative data in molecular epidemiology studies. For many carcinogens and mechanistic pathways, in particular nongenotoxic carcinogenicity, valid biological markers still need to be identified.

Carcinogenicity of glyphosate: why is New Zealand's EPA lost in the weeds?

PubMed

Douwes, Jeroen; 't Mannetje, Andrea; McLean, Dave; Pearce, Neil; Woodward, Alistair; Potter, John D

2018-03-23

In 2015, the International Agency for Research on Cancer (IARC) concluded that glyphosate is "probably carcinogenic to humans". The New Zealand Environmental Protection Authority (NZEPA) rejected this and commissioned a new report, concluding that glyphosate was unlikely to be genotoxic or carcinogenic to humans. The NZEPA has argued that the difference arose because IARC is a "hazard-identification authority", whereas NZEPA is a "regulatory body that needs to cast the net more widely". We conclude that the NZEPA process for evaluating the carcinogenicity of glyphosate was flawed and the post hoc justification invalid: there is no mention of risk assessment or "net-benefit approach" in the NZEPA report; and there is no discussion of current New Zealand glyphosate exposures. Further, the NZEPA report quotes heavily from the European Food Safety Authority (EFSA) report, which is itself markedly flawed, and like the NZEPA report, relies heavily on industry-funded and industry-manipulated reviews. Given the scientific flaws in both reports we urge that: the NZEPA report be withdrawn; the NZEPA respond to the concerns raised and for a reassessment to be conducted; and clearer process and better understanding of science be used to inform any future review of hazardous substances in New Zealand.

Public health agencies' obligations and the case of Zika.

PubMed

Luna, Florencia

2017-10-01

This article focuses on the initial reactions to the Zika epidemic by national and international public health agencies. It presents and analyzes some responses public officials made about sexual and reproductive health at the inception of the epidemic. It also describes the different challenges and obligations faced by local and international public health agencies, as these have not been clearly outlined. The article argues that these agencies have different obligations and should fulfill them despite existing obstacles. While international agencies should honor their leadership role and make recommendations at a meta-level, local agencies should provide, in the case of Zika, a framework for empowerment and grant women the freedom to achieve sexual and reproductive health so that they can avoid the consequences of this epidemic. © 2017 John Wiley & Sons Ltd.

76 FR 72505 - Agency Information Collection Activity; Proposed Collection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-23

... DEPARTMENT OF THE TREASURY Internal Revenue Service Agency Information Collection Activity; Proposed Collection AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and request for... on proposed and/or continuing information collections, as required by the Paperwork Reduction Act of...

78 FR 62417 - Import Administration; Change of Agency Name

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2013-10-22

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Analysis of Air Toxics From NOAA WP-3 Aircraft Measurements During the TexAQS 2006 Campaign: Comparison With Emission Inventories and Additive Inhalation Risk Factors

NASA Astrophysics Data System (ADS)

Del Negro, L. A.; Warneke, C.; de Gouw, J. A.; Atlas, E.; Lueb, R.; Zhu, X.; Pope, L.; Schauffler, S.; Hendershot, R.; Washenfelder, R.; Fried, A.; Richter, D.; Walega, J. G.; Weibring, P.

2007-12-01

Benzene and nine other air toxics classified as human carcinogens by the International Agency for Research on Cancer (IARC) were measured from the NOAA WP-3 aircraft during the TexAQS 2006 campaign. In-situ measurements of benzene, measured with a PTR-MS instrument, are used to estimate emission fluxes for comparison with point source emission inventories developed by the Texas Commission on Environmental Quality. Mean and median mixing ratios for benzene, acetaldehyde, formaldehyde, 1,3-butadiene, carbon tetrachloride, chloroform, 1,2-dichloroethane, dibromoethane, dichloromethane, and vinyl chloride, encountered over the city of Houston during the campaign, are combined with inhalation unit risk factor values developed by the California Environmental Protection Agency and the United States Environmental Protection Agency to estimate the additive inhalation risk factor. This additive risk factor represents the risk associated with lifetime (70 year) exposure at the levels measured and should not be used as an absolute indicator of risk to individuals. However, the results are useful for assessments of changing relative risk over time, and for identifying dominant contributions to the overall air toxic risk.

48 CFR 702.170-9 - Head of agency.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Head of agency. 702.170-9 Section 702.170-9 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL DEFINITIONS OF WORDS AND TERMS Definitions 702.170-9 Head of agency. Head of agency means, for USAID, the...

Parasites and malignancies, a review, with emphasis on digestive cancer induced by Cryptosporidium parvum (Alveolata: Apicomplexa)

PubMed Central

Benamrouz, S.; Conseil, V.; Creusy, C.; Calderon, E.; Dei-Cas, E.; Certad, G.

2012-01-01

The International Agency for Research on Cancer (IARC) identifies ten infectious agents (viruses, bacteria, parasites) able to induce cancer disease in humans. Among parasites, a carcinogenic role is currently recognized to the digenetic trematodes Schistosoma haematobium, leading to bladder cancer, and to Clonorchis sinensis or Opisthorchis viverrini, which cause cholangiocarcinoma. Furthermore, several reports suspected the potential association of other parasitic infections (due to Protozoan or Metazoan parasites) with the development of neoplastic changes in the host tissues. The present work shortly reviewed available data on the involvement of parasites in neoplastic processes in humans or animals, and especially focused on the carcinogenic power of Cryptosporidium parvum infection. On the whole, infection seems to play a crucial role in the etiology of cancer. PMID:22348213

Parasites and malignancies, a review, with emphasis on digestive cancer induced by Cryptosporidium parvum (Alveolata: Apicomplexa).

PubMed

Benamrouz, S; Conseil, V; Creusy, C; Calderon, E; Dei-Cas, E; Certad, G

2012-05-01

The International Agency for Research on Cancer (IARC) identifies ten infectious agents (viruses, bacteria, parasites) able to induce cancer disease in humans. Among parasites, a carcinogenic role is currently recognized to the digenetic trematodes Schistosoma haematobium, leading to bladder cancer, and to Clonorchis sinensis or Opisthorchis viverrini, which cause cholangiocarcinoma. Furthermore, several reports suspected the potential association of other parasitic infections (due to Protozoan or Metazoan parasites) with the development of neoplastic changes in the host tissues. The present work shortly reviewed available data on the involvement of parasites in neoplastic processes in humans or animals, and especially focused on the carcinogenic power of Cryptosporidium parvum infection. On the whole, infection seems to play a crucial role in the etiology of cancer.

Deficits in agency in schizophrenia, and additional deficits in body image, body schema, and internal timing, in passivity symptoms.

PubMed

Graham, Kyran T; Martin-Iverson, Mathew T; Holmes, Nicholas P; Jablensky, Assen; Waters, Flavie

2014-01-01

Individuals with schizophrenia, particularly those with passivity symptoms, may not feel in control of their actions, believing them to be controlled by external agents. Cognitive operations that contribute to these symptoms may include abnormal processing in agency as well as body representations that deal with body schema and body image. However, these operations in schizophrenia are not fully understood, and the questions of general versus specific deficits in individuals with different symptom profiles remain unanswered. Using the projected-hand illusion (a digital video version of the rubber-hand illusion) with synchronous and asynchronous stroking (500 ms delay), and a hand laterality judgment task, we assessed sense of agency, body image, and body schema in 53 people with clinically stable schizophrenia (with a current, past, and no history of passivity symptoms) and 48 healthy controls. The results revealed a stable trait in schizophrenia with no difference between clinical subgroups (sense of agency) and some quantitative (specific) differences depending on the passivity symptom profile (body image and body schema). Specifically, a reduced sense of self-agency was a common feature of all clinical subgroups. However, subgroup comparisons showed that individuals with passivity symptoms (both current and past) had significantly greater deficits on tasks assessing body image and body schema, relative to the other groups. In addition, patients with current passivity symptoms failed to demonstrate the normal reduction in body illusion typically seen with a 500 ms delay in visual feedback (asynchronous condition), suggesting internal timing problems. Altogether, the results underscore self-abnormalities in schizophrenia, provide evidence for both trait abnormalities and state changes specific to passivity symptoms, and point to a role for internal timing deficits as a mechanistic explanation for external cues becoming a possible source of self-body input.

The International Atomic Energy Agency's activities in radiation medicine and cancer: promoting global health through diplomacy.

PubMed

Deatsch-Kratochvil, Amanda N; Pascual, Thomas Neil; Kesner, Adam; Rosenblatt, Eduardo; Chhem, Rethy K

2013-02-01

Global health has been an issue of seemingly low political importance in comparison with issues that have direct bearing on countries' national security. Recently, health has experienced a "political revolution" or a rise in political importance. Today, we face substantial global health challenges, from the spread of infectious disease, gaps in basic maternal and child health care, to the globalization of cancer. A recent estimate states that the "overall lifetime risk of developing cancer (both sexes) is expected to rise from more than one in three to one in two by 2015." These issues pose significant threats to international health security. To successfully combat these grave challenges, the international community must embrace and engage in global health diplomacy, defined by scholars Thomas Novotny and Vicanne Adams as a political activity aimed at improving global health, while at the same time maintaining and strengthening international relations. The IAEA (International Atomic Energy Agency) is an international organization with a unique mandate to "accelerate and enlarge the contribution of atomic energy to peace, health, and prosperity throughout the world." This article discusses global health diplomacy, reviews the IAEA's program activities in human health by focusing on radiation medicine and cancer, and the peaceful applications of atomic energy within the context of global health diplomacy. Copyright © 2013 Canadian Association of Radiologists. Published by Elsevier Inc. All rights reserved.

Neurology and international organizations.

PubMed

Mateen, Farrah J

2013-07-23

A growing number of international stakeholders are engaged with neurologic diseases. This article provides a brief overview of important international stakeholders in the practice of neurology, including global disease-specific programs, United Nations agencies, governmental agencies with international influence, nongovernmental organizations, international professional organizations, large private donors, private-public partnerships, commercial interests, armed forces, and universities and colleges. The continued engagement of neurologists is essential for the growing number of international organizations that can and should incorporate neurologic disease into their global agendas.

Neurology and international organizations

PubMed Central

2013-01-01

A growing number of international stakeholders are engaged with neurologic diseases. This article provides a brief overview of important international stakeholders in the practice of neurology, including global disease-specific programs, United Nations agencies, governmental agencies with international influence, nongovernmental organizations, international professional organizations, large private donors, private–public partnerships, commercial interests, armed forces, and universities and colleges. The continued engagement of neurologists is essential for the growing number of international organizations that can and should incorporate neurologic disease into their global agendas. PMID:23877795

'My body is mine': Qualitatively exploring agency among internally displaced women participants in a small-group intervention in Leogane, Haiti.

PubMed

Logie, Carmen H; Daniel, CarolAnn

2016-01-01

The 2010 earthquake resulted in the breakdown of Haiti's social, economic and health infrastructure. Over one-quarter of a million people remain internally displaced (ID). ID women experience heightened vulnerability to intimate partner violence (IPV) due to increased poverty and reduced community networks. Scant research has examined experiences of IPV among ID women in post-earthquake Haiti. We conducted a qualitative study to explore the impact of participating in Famn an Aksyon Pou Santé Yo (FASY), a small-group HIV prevention intervention, on ID women's agency in Leogane, Haiti. We conducted four focus groups with ID women, FASY participants (n = 40) and in-depth individual interviews with peer health workers (n = 7). Our study was guided by critical ethnography and paid particular attention to power relations. Findings highlighted multiple forms of IPV (e.g., physical, sexual). Participants discussed processes of intrapersonal (confidence), interpersonal (communication), relational (support) and collective (women's rights) agency. Yet structural factors, including patriarchal gender norms and poverty, silenced IPV discussions and constrained women's agency. Findings suggest that agency among ID women is a multi-level, non-linear and incremental process. To effectively address IPV among ID women in Haiti, interventions should address structural contexts of gender inequity and poverty and concurrently facilitate multi-level processes of agency.

Mexican Space Agency and NASA Agreement

NASA Image and Video Library

2013-03-18

John Grunsfeld (far left), Associate Administrator for the Science Mission Directorate at NASA Headquarters, Dr. Francisco Javier Mendieta Jimenez, Director General of the Mexican Space Agency, NASA Administrator Charles Bolden, Leland Melvin, NASA Associate Administrator for Education and Al Condes (far right), Deputy Associate Administrator for International and Interagency Relations pose for a photo, Monday, March 18, 2013 at NASA Headquarters in Washington. A Reimbursable Space Act Agreement (RSAA) for a NASA International Internship Program was signed between the two agencies. This is the first NASA-Mexico agreement signed. Photo Credit: (NASA/Carla Cioffi)

36 CFR 1256.48 - Information about internal agency rules and practices.

Code of Federal Regulations, 2010 CFR

2010-07-01

... states or assesses an agency's vulnerability to outside interference or harm. NARA withholds records that... describing specific measures that can be used to counteract such agency vulnerabilities. (b) The Archivist of...

Medical physics in Europe following recommendations of the International Atomic Energy Agency.

PubMed

Casar, Bozidar; Lopes, Maria do Carmo; Drljević, Advan; Gershkevitsh, Eduard; Pesznyak, Csilla

2016-03-01

Medical physics is a health profession where principles of applied physics are mostly directed towards the application of ionizing radiation in medicine. The key role of the medical physics expert in safe and effective use of ionizing radiation in medicine was widely recognized in recent European reference documents like the European Union Council Directive 2013/59/EURATOM (2014), and European Commission Radiation Protection No. 174, European Guidelines on Medical Physics Expert (2014). Also the International Atomic Energy Agency (IAEA) has been outspoken in supporting and fostering the status of medical physics in radiation medicine through multiple initiatives as technical and cooperation projects and important documents like IAEA Human Health Series No. 25, Roles and Responsibilities, and Education and Training Requirements for Clinically Qualified Medical Physicists (2013) and the International Basic Safety Standards, General Safety Requirements Part 3 (2014). The significance of these documents and the recognition of the present insufficient fulfilment of the requirements and recommendations in many European countries have led the IAEA to organize in 2015 the Regional Meeting on Medical Physics in Europe, where major issues in medical physics in Europe were discussed. Most important outcomes of the meeting were the recommendations addressed to European member states and the survey on medical physics status in Europe conducted by the IAEA and European Federation of Organizations for Medical Physics. Published recommendations of IAEA Regional Meeting on Medical Physics in Europe shall be followed and enforced in all European states. Appropriate qualification framework including education, clinical specialization, certification and registration of medical physicists shall be established and international recommendation regarding staffing levels in the field of medical physics shall be fulfilled in particular. European states have clear legal and moral

Medical physics in Europe following recommendations of the International Atomic Energy Agency

PubMed Central

Lopes, Maria do Carmo; Drljević, Advan; Gershkevitsh, Eduard; Pesznyak, Csilla

2016-01-01

Background Medical physics is a health profession where principles of applied physics are mostly directed towards the application of ionizing radiation in medicine. The key role of the medical physics expert in safe and effective use of ionizing radiation in medicine was widely recognized in recent European reference documents like the European Union Council Directive 2013/59/EURATOM (2014), and European Commission Radiation Protection No. 174, European Guidelines on Medical Physics Expert (2014). Also the International Atomic Energy Agency (IAEA) has been outspoken in supporting and fostering the status of medical physics in radiation medicine through multiple initiatives as technical and cooperation projects and important documents like IAEA Human Health Series No. 25, Roles and Responsibilities, and Education and Training Requirements for Clinically Qualified Medical Physicists (2013) and the International Basic Safety Standards, General Safety Requirements Part 3 (2014). The significance of these documents and the recognition of the present insufficient fulfilment of the requirements and recommendations in many European countries have led the IAEA to organize in 2015 the Regional Meeting on Medical Physics in Europe, where major issues in medical physics in Europe were discussed. Most important outcomes of the meeting were the recommendations addressed to European member states and the survey on medical physics status in Europe conducted by the IAEA and European Federation of Organizations for Medical Physics. Conclusions Published recommendations of IAEA Regional Meeting on Medical Physics in Europe shall be followed and enforced in all European states. Appropriate qualification framework including education, clinical specialization, certification and registration of medical physicists shall be established and international recommendation regarding staffing levels in the field of medical physics shall be fulfilled in particular. European states have clear

The International Planetary Data Alliance

NASA Astrophysics Data System (ADS)

Stein, T.; Arviset, C.; Crichton, D. J.

2017-12-01

The International Planetary Data Alliance (IPDA) is an association of partners with the aim of improving the quality of planetary science data and services to the end users of space based instrumentation. The specific mission of the IPDA is to facilitate global access to, and exchange of, high quality scientific data products managed across international boundaries. Ensuring proper capture, accessibility and availability of the data is the task of the individual member space agencies. The IPDA was formed in 2006 with the purpose of adopting standards and developing collaborations across agencies to ensure data is captured in common formats. Member agencies include: Armenian Astronomical Society, China National Space Agency (CNSA), European Space Agency (ESA), German Aerospace Center (DLR), Indian Space Research Organization (ISRO), Italian Space Agency (ASI), Japanese Aerospace Exploration Agency (JAXA), National Air and Space Administration (NASA), National Centre for Space Studies (CNES), Space Research Institute (IKI), UAE Space Agency, and UK Space Agency. The IPDA Steering Committee oversees the execution of projects and coordinates international collaboration. The IPDA conducts a number of focused projects to enable interoperability, construction of compatible archives, and the operation of the IPDA as a whole. These projects have helped to establish the IPDA and to move the collaboration forward. A key project that is currently underway is the implementation of the PDS4 data standard. Given the international focus, it has been critical that the PDS and the IPDA collaborate on its development. Also, other projects have been conducted successfully, including developing the IPDA architecture and corresponding requirements, developing shared registries for data and tools across international boundaries, and common templates for supporting agreements for archiving and sharing data for international missions. Several projects demonstrating interoperability across

Analytical progresses of the International Olympic Committee and World Anti-Doping Agency Olympic laboratories.

PubMed

Georgakopoulos, Costas; Saugy, Martial; Giraud, Sylvain; Robinson, Neil; Alsayrafi, Mohammed

2012-07-01

The Summer Olympic Games constitute the biggest concentration of human sports and activities in a particular place and time since 776 BCE, when the written history of the Olympic Games in Olympia began. Summer and Winter Olympic anti-doping laboratories, accredited by the International Olympic Committee in the past and the World Anti-Doping Agency in the present times, acquire worldwide interest to apply all new analytical advancements in the fight against doping in sports, hoping that this major human event will not become dirty by association with this negative phenomenon. This article summarizes the new analytical progresses, technologies and knowledge used by the Olympic laboratories, which for the vast majority of them are, eventually, incorporated into routine anti-doping analysis.

Carcinogenic compounds in alcoholic beverages: an update.

PubMed

Pflaum, Tabea; Hausler, Thomas; Baumung, Claudia; Ackermann, Svenja; Kuballa, Thomas; Rehm, Jürgen; Lachenmeier, Dirk W

2016-10-01

The consumption of alcoholic beverages has been classified as carcinogenic to humans by the International Agency for Research on Cancer (IARC) since 1988. More recently, in 2010, ethanol as the major constituent of alcoholic beverages and its metabolite acetaldehyde were also classified as carcinogenic to humans. Alcoholic beverages as multi-component mixtures may additionally contain further known or suspected human carcinogens as constituent or contaminant. This review will discuss the occurrence and toxicology of eighteen carcinogenic compounds (acetaldehyde, acrylamide, aflatoxins, arsenic, benzene, cadmium, ethanol, ethyl carbamate, formaldehyde, furan, glyphosate, lead, 3-MCPD, 4-methylimidazole, N-nitrosodimethylamine, pulegone, ochratoxin A, safrole) occurring in alcoholic beverages as identified based on monograph reviews by the IARC. For most of the compounds of alcoholic beverages, quantitative risk assessment provided evidence for only a very low risk (such as margins of exposure above 10,000). The highest risk was found for ethanol, which may reach exposures in ranges known to increase the cancer risk even at moderate drinking (margin of exposure around 1). Other constituents that could pose a risk to the drinker were inorganic lead, arsenic, acetaldehyde, cadmium and ethyl carbamate, for most of which mitigation by good manufacturing practices is possible. Nevertheless, due to the major effect of ethanol, the cancer burden due to alcohol consumption can only be reduced by reducing alcohol consumption in general or by lowering the alcoholic strength of beverages.

IARC classes 1 and 2 carcinogens are successfully identified by an alternative strategy that detects DNA-reactivity and cell transformation ability of chemicals.

PubMed

Benigni, Romualdo; Bossa, Cecilia; Battistelli, Chiara Laura; Tcheremenskaia, Olga

2013-12-12

For decades, traditional toxicology has been the ultimate source of information on the carcinogenic potential of chemicals; however with increasing demand on regulation of chemicals and decreasing resources for testing, opportunities to accept "alternative" approaches have dramatically expanded. The need for tools able to identify carcinogens in shorter times and at a lower cost in terms of animal lives and money is still an open issue, and the present strategies and regulations for carcinogenicity pre-screening do not adequately protect human health. In previous papers, we have proposed an integrated in vitro/in silico strategy that detects DNA-reactivity and tissue disorganization/disruption by chemicals, and we have shown that the combination of Salmonella and Structural Alerts for the DNA-reactive carcinogens, and in vitro cell transformation assays for nongenotoxic carcinogens permits the identification of a very large proportion (up to 95%) of rodent carcinogens, while having a considerable specificity with the rodent noncarcinogens. In the present paper we expand the previous investigation and show that this alternative strategy identifies correctly IARC Classes 1 and 2 carcinogens. If implemented, this alternative strategy can contribute to improve the protection of human health while decreasing the use of animals. Copyright © 2013 Elsevier B.V. All rights reserved.

Matters Arising. Australian University Quality Agency Feedback in Relation to the Academic Engagement of International Students Enrolled in Onshore University Programmes

ERIC Educational Resources Information Center

Crossman, Joanna; Burdett, Jane

2012-01-01

It is now commonplace to find quality audit processes being applied in universities internationally as a means of assessing the quality of teaching and learning. This article draws upon a thematic analysis of 14 second-round Australian Universities Quality Agency reports in order to explore matters arising from the academic engagement of…

48 CFR 719.271 - Agency program direction and operation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Agency program direction and operation. 719.271 Section 719.271 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 719.271 Agency program direction and...

48 CFR 719.271 - Agency program direction and operation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Agency program direction and operation. 719.271 Section 719.271 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 719.271 Agency program direction and...

International Energy: Subject Thesaurus. Revision 1

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The International Energy Agency: Subject Thesaurus contains the standard vocabulary of indexing terms (descriptors) developed and structured to build and maintain energy information databases. Involved in this cooperative task are (1) the technical staff of the USDOE Office of Scientific and Technical Information (OSTI) in cooperation with the member countries of the International Energy Agency`s Energy Technology Data Exchange (ETDE) and (2) the International Atomic Energy Agency`s International Nuclear Information System (INIS) staff representing the more than 100 countries and organizations that record and index information for the international nuclear information community. ETDE member countries are also members of INIS.more » Nuclear information prepared for INIS by ETDE member countries is included in the ETDE Energy Database, which contains the online equivalent of the printed INIS Atomindex. Indexing terminology is therefore cooperatively standardized for use in both information systems. This structured vocabulary reflects thscope of international energy research, development, and technological programs. The terminology of this thesaurus aids in subject searching on commercial systems, such as ``Energy Science & Technology`` by DIALOG Information Services, ``Energy`` by STN International and the ``ETDE Energy Database`` by SilverPlatter. It is also the thesaurus for the Integrated Technical Information System (ITIS) online databases of the US Department of Energy.« less

28 CFR 94.52 - Final agency decision.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Final agency decision. 94.52 Section 94.52 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIME VICTIM SERVICES International Terrorism Victim Expense Reimbursement Program Appeal Procedures § 94.52 Final agency decision. In cases...

28 CFR 94.52 - Final agency decision.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 28 Judicial Administration 2 2013-07-01 2013-07-01 false Final agency decision. 94.52 Section 94.52 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIME VICTIM SERVICES International Terrorism Victim Expense Reimbursement Program Appeal Procedures § 94.52 Final agency decision. In cases...

28 CFR 94.52 - Final agency decision.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 28 Judicial Administration 2 2014-07-01 2014-07-01 false Final agency decision. 94.52 Section 94.52 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIME VICTIM SERVICES International Terrorism Victim Expense Reimbursement Program Appeal Procedures § 94.52 Final agency decision. In cases...

28 CFR 94.52 - Final agency decision.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 28 Judicial Administration 2 2012-07-01 2012-07-01 false Final agency decision. 94.52 Section 94.52 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIME VICTIM SERVICES International Terrorism Victim Expense Reimbursement Program Appeal Procedures § 94.52 Final agency decision. In cases...

28 CFR 94.52 - Final agency decision.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 28 Judicial Administration 2 2011-07-01 2011-07-01 false Final agency decision. 94.52 Section 94.52 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) CRIME VICTIM SERVICES International Terrorism Victim Expense Reimbursement Program Appeal Procedures § 94.52 Final agency decision. In cases...

Health Research Funding Agencies' Support and Promotion of Knowledge Translation: An International Study

PubMed Central

Tetroe, Jacqueline M; Graham, Ian D; Foy, Robbie; Robinson, Nicole; Eccles, Martin P; Wensing, Michel; Durieux, Pierre; Légaré, France; Nielson, Camilla Palmhøj; Adily, Armita; Ward, Jeanette E; Porter, Cassandra; Shea, Beverley; Grimshaw, Jeremy M

2008-01-01

Context The process of knowledge translation (KT) in health research depends on the activities of a wide range of actors, including health professionals, researchers, the public, policymakers, and research funders. Little is known, however, about health research funding agencies' support and promotion of KT. Our team asked thirty-three agencies from Australia, Canada, France, the Netherlands, Scandinavia, the United Kingdom, and the United States about their role in promoting the results of the research they fund. Methods Semistructured interviews were conducted with a sample of key informants from applied health funding agencies identified by the investigators. The interviews were supplemented with information from the agencies' websites. The final coding was derived from an iterative thematic analysis. Findings There was a lack of clarity between agencies as to what is meant by KT and how it is operationalized. Agencies also varied in their degree of engagement in this process. The agencies' abilities to create a pull for research findings; to engage in linkage and exchange between agencies, researchers, and decision makers; and to push results to various audiences differed as well. Finally, the evaluation of the effectiveness of KT strategies remains a methodological challenge. Conclusions Funding agencies need to think about both their conceptual framework and their operational definition of KT, so that it is clear what is and what is not considered to be KT, and adjust their funding opportunities and activities accordingly. While we have cataloged the range of knowledge translation activities conducted across these agencies, little is known about their effectiveness and so a greater emphasis on evaluation is needed. It would appear that “best practice” for funding agencies is an elusive concept depending on the particular agency's size, context, mandate, financial considerations, and governance structure. PMID:18307479

Internation Cooperation.

ERIC Educational Resources Information Center

Scheeder, Donna; And Others

1990-01-01

Special libraries abroad and international cooperative efforts are discussed in six articles. Topics covered include the international role of the Special Libraries Association; the Special Library Program of the U.S. Information Agency; the design of special libraries abroad; regional networks that cross international boundaries; and the…

Wi-Fi technology--an uncontrolled global experiment on the health of mankind.

PubMed

Markov, Marko; Grigoriev, Yuri G

2013-06-01

The twenty-first century is marked with exponentially increasing development of technologies that provide wireless communications. To the pollution of the atmosphere with radio and TV signals, not only satellite communications but also any varieties of the Wi-Fi networks are added. By 2010 in the USA, 285 million mobile phone subscribers have been registered (for a little bit more than 300 million inhabitants). The estimate for the world is more than 5 billion mobile phone users at approximately 7 billion people living on this planet. Approximately 2 years ago, the International Agency of Research on Cancer (IARC) classified the electromagnetic fields used in mobile communication as a possible cancerogene. This paper discusses the potential health hazard and lack of scientific assessment and regulatory actions in protection of the life on the planet.

Multinational Advertising Agencies in Latin America.

ERIC Educational Resources Information Center

Fejes, Fred

An overview of the international expansion of advertising agencies based in the United States is presented in the first part of this paper. The various types of strategies used by the agencies in their expansion efforts are discussed along with some of the problems they have faced. The second part of the paper focuses specifically on the expansion…

48 CFR 719.273-10 - Internal controls.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Internal controls. 719.273-10 Section 719.273-10 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS The U.S. Agency for International Development (USAID) Mentor-Protégé Program 719.273-10 Internal...

The hospital based staffing agency.

PubMed

Manion, J; Reid, S B

1989-01-01

Before a hospital considers creating an internal staffing agency, a detailed business plan must be developed. By addressing marketing and operational issues in advance, nurse executives can avoid unnecessary business problems.

Review for the Korean Health Professionals and International Cooperation Doctors Dispatched to Peru by the Korea International Cooperation Agency (KOICA).

PubMed

Kim, Bongyoung

2015-04-01

South Korea dispatches Korean nationals to partner developing countries as an Official Development Assistance (ODA) project through the Korea International Cooperation Agency (KOICA). In the health sector, KOICA dispatches international cooperation doctors (ICDs), nurses, physical therapists, radiologic technologists, nutritionists, medical laboratory technologists, occupational therapists, and dental hygienists. A total of 216 ICDs were dispatched over 19 times from 1995 until 2013. There were 19 areas of specialties among the ICDs. The most common specialty was internal medicine (61/216, 28.2%), the second most common specialty was general surgery (43/216, 19.9%), followed by oriental medicine (27/216, 12.5%), pediatrics (17/216, 7.9%), orthopedics (16/216, 7.4%), family medicine (16/216, 7.4%), and odontology (14/216, 6.5%). The ICDs have worked in 21 countries. KOICA dispatched the highest number of ICDs to Asia (97/216, 44.9%), followed by Africa (50/216, 23.1%), Latin America (34/216, 15.7%), the commonwealth of independent states (31/216, 14.4%), and Oceania (4/216, 1.9%). Nobody was dispatched to the Middle East. A total of 134 KOICA health professionals were dispatched to Peru from 1996 until October 1, 2014. Of these, 19.4% (26/134) were ICDs, 44.8% (60/216) were nurses, 20.1% (27/134) were physical therapists, 6.7% (9/134) were radiologic technologists, 2.2% (3/134) were nutritionists, and 6.7% (9/134) were medical laboratory. ICDs' specialties comprised internal medicine (13/26, 50%), family medicine (8/26, 30.8%), pediatrics (2/26, 7.7%), otorhinolaryngology (1/26, 3.8%), orthopedics (1/26, 3.8%), and oriental medicine (1/26, 3.8%). Most of the dispatched health professionals worked at institutions that were supported by KOICA. For this reason, the proportion of health professionals who worked at public health centers (PHCs) was the highest (58.2%, 78/134) when classified by workplace type. Other KOICA health professionals worked at hospitals

Testing the validity of the International Atomic Energy Agency (IAEA) safety culture model.

PubMed

López de Castro, Borja; Gracia, Francisco J; Peiró, José M; Pietrantoni, Luca; Hernández, Ana

2013-11-01

This paper takes the first steps to empirically validate the widely used model of safety culture of the International Atomic Energy Agency (IAEA), composed of five dimensions, further specified by 37 attributes. To do so, three independent and complementary studies are presented. First, 290 students serve to collect evidence about the face validity of the model. Second, 48 experts in organizational behavior judge its content validity. And third, 468 workers in a Spanish nuclear power plant help to reveal how closely the theoretical five-dimensional model can be replicated. Our findings suggest that several attributes of the model may not be related to their corresponding dimensions. According to our results, a one-dimensional structure fits the data better than the five dimensions proposed by the IAEA. Moreover, the IAEA model, as it stands, seems to have rather moderate content validity and low face validity. Practical implications for researchers and practitioners are included. Copyright © 2013 Elsevier Ltd. All rights reserved.

48 CFR 732.406-70 - Agency-issued letters of credit.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Agency-issued letters of credit. 732.406-70 Section 732.406-70 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Advance Payments 732.406-70 Agency-issued...

48 CFR 732.406-70 - Agency-issued letters of credit.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Agency-issued letters of credit. 732.406-70 Section 732.406-70 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Advance Payments 732.406-70 Agency-issued...

Technical Cooperation with Iran: A Case Study of Opportunities and Policy Implications for the United States. Report to the Agency for International Development.

ERIC Educational Resources Information Center

Agency for International Development (Dept. of State), Washington, DC.

This report concerns aspects of the United States' changing policies for providing economic and technical assistance to developing nations. Of primary importance in a review of relationships with those rapidly developing nations no longer eligible for concessional assistance from the Agency for International Development (AID) are the possible…

77 FR 40879 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-11

... Compression Ignition Internal Combustion Engines (Renewal) AGENCY: Environmental Protection Agency (EPA....regulations.gov . Title: NSPS for Stationary Source Compression Ignition Internal Combustion Engines (Renewal... Performance Standards (NSPS) for Stationary Source Compression Ignition Internal Combustion Engines (40 CFR...

75 FR 39584 - Agency Information Collection Activities: Comment Request

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-09

... National Science Foundation's East Asia and Pacific Summer Institutes and International Research Fellowship... NATIONAL SCIENCE FOUNDATION Agency Information Collection Activities: Comment Request AGENCY: National Science Foundation. ACTION: Notice; Submission for OMB Review; Comment Request. SUMMARY: The...

22 CFR 212.37 - Procedures for agency consideration of appeals.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Procedures for agency consideration of appeals. 212.37 Section 212.37 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT PUBLIC INFORMATION Access... of the decisions and of the provisions for judicial review of the Agency's denial of the request. (c...

The International Planetary Data Alliance (IPDA)

NASA Astrophysics Data System (ADS)

Stein, Thomas; Gopala Krishna, Barla; Crichton, Daniel J.

2016-07-01

The International Planetary Data Alliance (IPDA) is a close association of partners with the aim of improving the quality of planetary science data and services to the end users of space based instrumentation. The specific mission of the IPDA is to facilitate global access to, and exchange of, high quality scientific data products managed across international boundaries. Ensuring proper capture, accessibility and availability of the data is the task of the individual member space agencies. The IPDA is focused on developing an international standard that allows discovery, query, access, and usage of such data across international planetary data archive systems. While trends in other areas of space science are concentrating on the sharing of science data from diverse standards and collection methods, the IPDA concentrates on promoting governing data standards that drive common methods for collecting and describing planetary science data across the international community. This approach better supports the long term goal of easing data sharing across system and agency boundaries. An initial starting point for developing such a standard will be internationalization of NASA's Planetary Data System's (PDS) PDS4 standard. The IPDA was formed in 2006 with the purpose of adopting standards and developing collaborations across agencies to ensure data is captured in common formats. It has grown to a dozen member agencies represented by a number of different groups through the IPDA Steering Committee. Member agencies include: Armenian Astronomical Society, China National Space Agency (CNSA), European Space Agency (ESA), German Aerospace Center (DLR), Indian Space Research Organization (ISRO), Italian Space Agency (ASI), Japanese Aerospace Exploration Agency (JAXA), National Air and Space Administration (NASA), National Centre for Space Studies (CNES), Space Research Institute (IKI), UAE Space Agency, and UK Space Agency. The IPDA Steering Committee oversees the execution of

78 FR 69288 - Import Administration; Change of Agency Name

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-19

...] RIN 0625-AA98 Import Administration; Change of Agency Name AGENCY: Foreign-Trade Zones Board, International Trade Administration, Commerce. ACTION: Final rule; nomenclature change. SUMMARY: Effective... orders, changed the name of ``Import Administration'' to ``Enforcement and Compliance.'' Consistent with...

KENNEDY SPACE CENTER, FLA. - At ceremony highlighting the arrival of two major components of the International Space Station, Node 2 and the Japanese Experiment Module (JEM), ownership of Node 2 was officially transferred between the European Space Agency and NASA. Shaking hands after the signing are Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; and Alan Thirkettle, International Space Station Program manager for Node 2, European Space Agency (ESA). At right is NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs. NASA's Node 2, built by ESA in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s William Gerstenmaier, International Space Station Program manager; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - At ceremony highlighting the arrival of two major components of the International Space Station, Node 2 and the Japanese Experiment Module (JEM), ownership of Node 2 was officially transferred between the European Space Agency and NASA. Shaking hands after the signing are Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; and Alan Thirkettle, International Space Station Program manager for Node 2, European Space Agency (ESA). At right is NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs. NASA's Node 2, built by ESA in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s William Gerstenmaier, International Space Station Program manager; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

KENNEDY SPACE CENTER, FLA. - Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; Alan Thirkettle, International Space Station Program manager for Node 2, European Space Agency (ESA); and NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, sign documents officially transferring ownership of Node 2 between the ESA and NASA. The signing was part of a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module (above right) of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. Emceed by Lisa Malone (far left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s William Gerstenmaier, International Space Station Program manager; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; Alan Thirkettle, International Space Station Program manager for Node 2, European Space Agency (ESA); and NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, sign documents officially transferring ownership of Node 2 between the ESA and NASA. The signing was part of a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module (above right) of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. Emceed by Lisa Malone (far left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s William Gerstenmaier, International Space Station Program manager; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

KENNEDY SPACE CENTER, FLA. - Alan Thirkettle, International Space Station Program manager for Node 2, European Space Agency (ESA), speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs and William Gerstenmaier, International Space Station Program manager; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - Alan Thirkettle, International Space Station Program manager for Node 2, European Space Agency (ESA), speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs and William Gerstenmaier, International Space Station Program manager; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

Decreased survival of glioma patients with astrocytoma grade IV (glioblastoma multiforme) associated with long-term use of mobile and cordless phones.

PubMed

Carlberg, Michael; Hardell, Lennart

2014-10-16

On 31 May 2011 the WHO International Agency for Research on Cancer (IARC) categorised radiofrequency electromagnetic fields (RF-EMFs) from mobile phones, and from other devices that emit similar non-ionising electromagnetic fields, as a Group 2B, i.e., a "possible", human carcinogen. A causal association would be strengthened if it could be shown that the use of wireless phones has an impact on the survival of glioma patients. We analysed survival of 1678 glioma patients in our 1997-2003 and 2007-2009 case-control studies. Use of wireless phones in the >20 years latency group (time since first use) yielded an increased hazard ratio (HR) = 1.7, 95% confidence interval (CI) = 1.2-2.3 for glioma. For astrocytoma grade IV (glioblastoma multiforme; n = 926) mobile phone use yielded HR = 2.0, 95% CI = 1.4-2.9 and cordless phone use HR = 3.4, 95% CI = 1.04-11 in the same latency category. The hazard ratio for astrocytoma grade IV increased statistically significant per year of latency for wireless phones, HR = 1.020, 95% CI = 1.007-1.033, but not per 100 h cumulative use, HR = 1.002, 95% CI = 0.999-1.005. HR was not statistically significant increased for other types of glioma. Due to the relationship with survival the classification of IARC is strengthened and RF-EMF should be regarded as human carcinogen requiring urgent revision of current exposure guidelines.

Report to the U.S. Agency for International Development on the Activities of Literacy House, Lucknow, India, July 1, 1964 - June 30, 1969.

ERIC Educational Resources Information Center

World Education, Inc., New York, NY.

The program of Literacy House in Lucknow, India includes training of personnel, preparation of materials, and sponsorship of a wide variety of programs. This report on their work, prepared to document the need for a budget request from the U.S. Agency for International Development, describes the achievement and prospects in programs relating to…

Databases applicable to quantitative hazard/risk assessment-Towards a predictive systems toxicology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Waters, Michael; Jackson, Marcus

2008-11-15

The Workshop on The Power of Aggregated Toxicity Data addressed the requirement for distributed databases to support quantitative hazard and risk assessment. The authors have conceived and constructed with federal support several databases that have been used in hazard identification and risk assessment. The first of these databases, the EPA Gene-Tox Database was developed for the EPA Office of Toxic Substances by the Oak Ridge National Laboratory, and is currently hosted by the National Library of Medicine. This public resource is based on the collaborative evaluation, by government, academia, and industry, of short-term tests for the detection of mutagens andmore » presumptive carcinogens. The two-phased evaluation process resulted in more than 50 peer-reviewed publications on test system performance and a qualitative database on thousands of chemicals. Subsequently, the graphic and quantitative EPA/IARC Genetic Activity Profile (GAP) Database was developed in collaboration with the International Agency for Research on Cancer (IARC). A chemical database driven by consideration of the lowest effective dose, GAP has served IARC for many years in support of hazard classification of potential human carcinogens. The Toxicological Activity Profile (TAP) prototype database was patterned after GAP and utilized acute, subchronic, and chronic data from the Office of Air Quality Planning and Standards. TAP demonstrated the flexibility of the GAP format for air toxics, water pollutants and other environmental agents. The GAP format was also applied to developmental toxicants and was modified to represent quantitative results from the rodent carcinogen bioassay. More recently, the authors have constructed: 1) the NIEHS Genetic Alterations in Cancer (GAC) Database which quantifies specific mutations found in cancers induced by environmental agents, and 2) the NIEHS Chemical Effects in Biological Systems (CEBS) Knowledgebase that integrates genomic and other biological data

Agency Video, Audio and Imagery Library

NASA Technical Reports Server (NTRS)

Grubbs, Rodney

2015-01-01

The purpose of this presentation was to inform the ISS International Partners of the new NASA Agency Video, Audio and Imagery Library (AVAIL) website. AVAIL is a new resource for the public to search for and download NASA-related imagery, and is not intended to replace the current process by which the International Partners receive their Space Station imagery products.

26 CFR 1.597-4 - Bridge Banks and Agency Control.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 26 Internal Revenue 7 2011-04-01 2009-04-01 true Bridge Banks and Agency Control. 1.597-4 Section... (CONTINUED) INCOME TAXES (CONTINUED) Mutual Savings Banks, Etc. § 1.597-4 Bridge Banks and Agency Control. (a) Scope. This section provides rules that apply to a Bridge Bank or other Institution under Agency Control...

26 CFR 1.597-4 - Bridge Banks and Agency Control.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 7 2010-04-01 2010-04-01 true Bridge Banks and Agency Control. 1.597-4 Section... (CONTINUED) INCOME TAXES (CONTINUED) Mutual Savings Banks, Etc. § 1.597-4 Bridge Banks and Agency Control. (a) Scope. This section provides rules that apply to a Bridge Bank or other Institution under Agency Control...

Aflatoxin control measures: A basis for improved health in developing countries

USDA-ARS?s Scientific Manuscript database

The goal of this IARC Working Group Report is to produce a document, based on expertly evaluated scientific evidence, which provides a set of clear, concise and focused messages to inform policymakers, international organizations and funders in their decision-making with regards to appropriate aflat...

48 CFR 733.103-70 - Protests to the agency.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Protests to the agency. 733.103-70 Section 733.103-70 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Protests 733.103-70 Protests to...

48 CFR 733.103-70 - Protests to the agency.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Protests to the agency. 733.103-70 Section 733.103-70 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT GENERAL CONTRACTING REQUIREMENTS PROTESTS, DISPUTES, AND APPEALS Protests 733.103-70 Protests to...

[The IARC carcinogenicity evaluation of radio-frequency electromagnetic field: with special reference to epidemiology of mobile phone use and brain tumor risk].

PubMed

Yamaguchi, Naohito

2013-01-01

The International Agency for Research on Cancer of World Health Organization announced in May 2011 the results of evaluation of carcinogenicity of radio-frequency electromagnetic field. In the overall evaluation, the radio-frequency electromagnetic field was classified as "possibly carcinogenic to humans", on the basis of the fact that the evidence provided by epidemiological studies and animal bioassays was limited. Regarding epidemiology, the results of the Interphone Study, an international collaborative case-control study, were of special importance, together with the results of a prospective cohort study in Denmark, case-control studies in several countries, and a case-case study in Japan. The evidence obtained was considered limited, because the increased risk observed in some studies was possibly spurious, caused by selection bias or recall bias as well as residual effects of confounding factors. Further research studies, such as large-scale multinational epidemiological studies, are crucially needed to establish a sound evidence base from which a more conclusive judgment can be made for the carcinogenicity of the radio-frequency electromagnetic field.

Rapid development of tissue bank achieved by International Atomic Energy Agency (IAEA) Tissue Banking Programme in China.

PubMed

Zhang, Yu-Min; Wang, Jian-Ru; Zhang, Nai-Li; Liu, Xiao-Ming; Zhou, Mo; Ma, Shao-Ying; Yang, Ting; Li, Bao-Xing

2014-09-01

Before 1986, the development of tissue banking in China has been slow and relatively uncoordinated. Under the support of International Atomic Energy Agency (IAEA), Tissue Banking in China experienced rapid development. In this period, China Institute for Radiation Protection tissue bank mastered systematic and modern tissue banking technique by IAEA training course and gradually developed the first regional tissue bank (Shanxi Provincial Tissue Bank, SPTB) to provide tissue allograft. Benefit from training course, SPTB promoted the development of tissue transplantation by ways of training, brochure, advertisement and meeting. Tissue allograft transplantation acquired recognition from clinic and supervision and administration from government. Quality system gradually is developing and perfecting. Tissue allograft transplantation and tissue bank are developing rapidly and healthy.

Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation

PubMed Central

Herceg, Zdenko

2013-01-01

Remarkable progress in the field of epigenetics has turned academic, medical and public attention to the potential applications of these new advances in medicine and various fields of biomedical research. The result is a broader appreciation of epigenetic phenomena in the a etiology of common human diseases, most notably cancer. These advances also represent an exciting opportunity to incorporate epigenetics and epigenomics into carcinogen identification and safety assessment. Current epigenetic studies, including major international sequencing projects, are expected to generate information for establishing the ‘normal’ epigenome of tissues and cell types as well as the physiological variability of the epigenome against which carcinogen exposure can be assessed. Recently, epigenetic events have emerged as key mechanisms in cancer development, and while our search of the Monograph Volume 100 revealed that epigenetics have played a modest role in evaluating human carcinogens by the International Agency for Research on Cancer (IARC) Monographs so far, epigenetic data might play a pivotal role in the future. Here, we review (i) the current status of incorporation of epigenetics in carcinogen evaluation in the IARC Monographs Programme, (ii) potential modes of action for epigenetic carcinogens, (iii) current in vivo and in vitro technologies to detect epigenetic carcinogens, (iv) genomic regions and epigenetic modifications and their biological consequences and (v) critical technological and biological issues in assessment of epigenetic carcinogens. We also discuss the issues related to opportunities and challenges in the application of epigenetic testing in carcinogen identification and evaluation. Although the application of epigenetic assays in carcinogen evaluation is still in its infancy, important data are being generated and valuable scientific resources are being established that should catalyse future applications of epigenetic testing. PMID:23749751

Introduction of International Microgravity Strategic Planning Group

NASA Technical Reports Server (NTRS)

Rhome, Robert

1998-01-01

Established in May 6, 1995, the purpose of this International Strategic Planning Group for Microgravity Science and Applications Research is to develop and update, at least on a biennial basis, an International Strategic Plan for Microgravity Science and Applications Research. The member space agencies have agreed to contribute to the development of a Strategic Plan, and seek the implementation of the cooperative programs defined in this Plan. The emphasis of this plan is the coordination of hardware construction and utilization within the various areas of research including biotechnology, combustion science, fluid physics, materials science and other special topics in physical sciences. The Microgravity Science and Applications International Strategic Plan is a joint effort by the present members - ASI, CNES, CSA, DLR, ESA, NASA, and NASDA. It represents the consensus from a series of discussions held within the International Microgravity Strategic Planning Group (IMSPG). In 1996 several space agencies initiated multilateral discussions on how to improve the effectiveness of international microgravity research during the upcoming Space Station era. These discussions led to a recognition of the need for a comprehensive strategic plan for international microgravity research that would provide a framework for cooperation between international agencies. The Strategic Plan is intended to provide a basis for inter-agency coordination and cooperation in microgravity research in the environment of the International Space Station (ISS) era. This will be accomplished through analysis of the interests and goals of each participating agency and identification of mutual interests and program compatibilities. The Plan provides a framework for maximizing the productivity of space-based research for the benefit of our societies.

Linking an agency strategic review to increase knowledge management: San Francisco County Human Service Agency.

PubMed

Harrison, Lindsay

2012-01-01

Led by the agency director, the agency engaged in a Strategic Review, based on a comprehensive assessment of agency performance that identified strategies to improve organizational effectiveness through increased data-informed practice and knowledge management. The Strategic Review gathered information on staff perceptions, perceptions of external stakeholders, changing citywide and neighborhood demographics, policy mandates, and budget and workload issues. The need for the review was based upon multiple, substantial changes not addressed in the 2000 Strategic Plan, including the 2004 merger of the Department of Human Services and the Department of Aging and Adult Services, changes among the executive management team, transitions among key political entities, new policy mandates and changing budget allocations. This case study describes the Strategic Review process and content, summarizing key challenges and lessons related to addressing workload demands, fostering positive staff attitudes, balancing internal and external information needs, and integrating data use and planning processes across the agency. Copyright © Taylor & Francis Group, LLC

Oil substitution and energy saving - A research and development strategy of the International Energy Agency /IEA/

NASA Astrophysics Data System (ADS)

Rath-Nagel, S.

1981-03-01

Systems analyses were carried out by the International Energy Agency for the participating 15 countries in order to work out strategies and scenarios for lessening the dependence on imported oil and for developing new energy technologies. MARKAL model computations show the technology and energy mixes necessary for achieving a reduction of oil imports by two thirds over the next 40 years. The scenario 'high social security' examines the projected rise in energy consumption, the development of oil substitutes, the increase in alternative heating sources, the development of markets for liquid energy products, the demand for gas, and the relative usage of various energy generation methods. The recommended strategy involves as the most important points an increase in coal consumption, greater nuclear energy reliance and development of alternative technologies.

Robotics research at Canadian Space Agency

NASA Technical Reports Server (NTRS)

Hui, Raymond

1994-01-01

In addition to major crown projects such as the Mobile Servicing System for Space Station, the Canadian Space Agency is also engaged in internal, industrial and academic research and development activities in robotics and other space-related areas of science and technology. These activities support current and future space projects, and lead to technology development which can be spun off to terrestrial applications, thus satisfying the Agency's objective of providing economic benefits to the public at large through its space-related work.

75 FR 14184 - Agency Information Collection Activities; Proposed Collection; Comments Requested

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-24

... Collection Under Review: International Terrorism Victim Compensation Program Application. The Department of...: International Terrorism Victim Expense Reimbursement Program (ITVERP) Application. (3) Agency form number, if... of international terrorism that occur outside the United States. Applicants seeking compensation from...

76 FR 7191 - Agency Information Collection Activities; Submission to OMB for Review and Approval; Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-09

... Internal Combustion Engines (Renewal) AGENCY: Environmental Protection Agency (EPA). ACTION: Notice... Combustion Engines (Renewal) ICR Numbers: EPA ICR Number 2227.03, OMB Control Number 2060-0610. ICR Status... internal combustion engines. Estimated Number of Respondents: 17,052. Frequency of Response: Initially and...

22 CFR 213.22 - Salary offset when USAID is the creditor agency.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Salary offset when USAID is the creditor agency. 213.22 Section 213.22 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION Administrative Offset § 213.22 Salary offset when USAID is the creditor agency. (a) Due process requirements...

22 CFR 213.22 - Salary offset when USAID is the creditor agency.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Salary offset when USAID is the creditor agency. 213.22 Section 213.22 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION Administrative Offset § 213.22 Salary offset when USAID is the creditor agency. (a) Due process requirements...

22 CFR 213.22 - Salary offset when USAID is the creditor agency.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Salary offset when USAID is the creditor agency. 213.22 Section 213.22 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION Administrative Offset § 213.22 Salary offset when USAID is the creditor agency. (a) Due process requirements...

22 CFR 213.22 - Salary offset when USAID is the creditor agency.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Salary offset when USAID is the creditor agency. 213.22 Section 213.22 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT CLAIMS COLLECTION Administrative Offset § 213.22 Salary offset when USAID is the creditor agency. (a) Due process requirements...

Atmospheric rivers emerge as a global science and applications focus

USGS Publications Warehouse

Ralph, F. Martin; Dettinger, Michael; Lavers, David A.; Gorodetskaya, Irina; Martin, Andrew; Viale, Maximilliano; White, Allen; Oakley, Nina; Rutz, Jonathan; Spackman, J. Ryan; Wernli, Heini; Cordeira, Jason

2017-01-01

Recent advances in atmospheric sciences and hydrology have identified the key role of atmo-spheric rivers (ARs) in determining the distribution of strong precipitation events in the midlatitudes. The growth of the subject is evident in the increase in scientific publications that discuss ARs (Fig. 1a). Combined with related phenomena, that is, warm conveyor belts (WCBs) and tropical moisture exports (TMEs), the frequency, position, and strength of ARs determine the occurrence of floods, droughts, and water resources in many parts of the world. A conference at the Scripps Institution of Oceanography in La Jolla, California, recently gathered over 100 experts in atmospheric, hydrologic, oceanic, and polar science; ecology; water management; and civil engineering to assess the state of AR science and to explore the need for new information. This first International Atmospheric Rivers Conference (IARC) allowed for much needed introductions and interactions across fields and regions, for example, participants came from five continents, and studies covered ARs in six continents and Greenland (Fig. 1b). IARC also fostered discussions of the status and future of AR science, and attendees strongly supported the idea of holding another IARC at the Scripps Institution of Oceanography in the summer of 2018.

A Management Model for International Participation in Space Exploration Missions

NASA Technical Reports Server (NTRS)

George, Patrick J.; Pease, Gary M.; Tyburski, Timothy E.

2005-01-01

This paper proposes an engineering management model for NASA's future space exploration missions based on past experiences working with the International Partners of the International Space Station. The authors have over 25 years of combined experience working with the European Space Agency, Japan Aerospace Exploration Agency, Canadian Space Agency, Italian Space Agency, Russian Space Agency, and their respective contractors in the design, manufacturing, verification, and integration of their elements electric power system into the United States on-orbit segment. The perspective presented is one from a specific sub-system integration role and is offered so that the lessons learned from solving issues of technical and cultural nature may be taken into account during the formulation of international partnerships. Descriptions of the types of unique problems encountered relative to interactions between international partnerships are reviewed. Solutions to the problems are offered, taking into consideration the technical implications. Through the process of investigating each solution, the important and significant issues associated with working with international engineers and managers are outlined. Potential solutions are then characterized by proposing a set of specific methodologies to jointly develop spacecraft configurations that benefits all international participants, maximizes mission success and vehicle interoperability while minimizing cost.

Toward an International Lunar Polar Volatiles Strategy

NASA Technical Reports Server (NTRS)

Gruener, J. E.; Suzuki, N. H.; Carpenter, J. D.

2015-01-01

Fourteen international space agencies are participating in the International Space Exploration Coordination Group (ISECG), working together to advance a long-range human space exploration strategy. The ISECG is a voluntary, non-binding international coordination mechanism through which individual agencies may exchange information regarding interests, objectives, and plans in space exploration with the goal of strengthening both individual exploration programs as well as the collective effort. The ISECG has developed a Global Exploration Roadmap (GER) that reflects the coordinated international dialog and continued preparation for exploration beyond low-Earth orbit - beginning with the Moon and cis-lunar space, and continuing to near-Earth asteroids, and Mars. Space agencies agree that human space exploration will be most successful as an international endeavor, given the challenges of these missions. The roadmap demonstrates how initial capabilities can enable a variety of missions in the lunar vicinity, responding to individual and common goals and objectives, while contributing to building partnerships required for sustainable human space exploration that delivers value to the public.

Accuracy requirements and uncertainties in radiotherapy: a report of the International Atomic Energy Agency.

PubMed

van der Merwe, Debbie; Van Dyk, Jacob; Healy, Brendan; Zubizarreta, Eduardo; Izewska, Joanna; Mijnheer, Ben; Meghzifene, Ahmed

2017-01-01

Radiotherapy technology continues to advance and the expectation of improved outcomes requires greater accuracy in various radiotherapy steps. Different factors affect the overall accuracy of dose delivery. Institutional comprehensive quality assurance (QA) programs should ensure that uncertainties are maintained at acceptable levels. The International Atomic Energy Agency has recently developed a report summarizing the accuracy achievable and the suggested action levels, for each step in the radiotherapy process. Overview of the report: The report seeks to promote awareness and encourage quantification of uncertainties in order to promote safer and more effective patient treatments. The radiotherapy process and the radiobiological and clinical frameworks that define the need for accuracy are depicted. Factors that influence uncertainty are described for a range of techniques, technologies and systems. Methodologies for determining and combining uncertainties are presented, and strategies for reducing uncertainties through QA programs are suggested. The role of quality audits in providing international benchmarking of achievable accuracy and realistic action levels is also discussed. The report concludes with nine general recommendations: (1) Radiotherapy should be applied as accurately as reasonably achievable, technical and biological factors being taken into account. (2) For consistency in prescribing, reporting and recording, recommendations of the International Commission on Radiation Units and Measurements should be implemented. (3) Each institution should determine uncertainties for their treatment procedures. Sample data are tabulated for typical clinical scenarios with estimates of the levels of accuracy that are practically achievable and suggested action levels. (4) Independent dosimetry audits should be performed regularly. (5) Comprehensive quality assurance programs should be in place. (6) Professional staff should be appropriately

78 FR 18321 - International Code Council: The Update Process for the International Codes and Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-26

... for Residential Construction in High Wind Regions. ICC 700: National Green Building Standard The..., coordinated, and necessary to regulate the built environment. Federal agencies frequently use these codes and... International Codes and Standards consist of the following: ICC Codes International Building Code. International...

Cancer in Experimental Animals Exposed to Arsenic and Arsenic Compounds

PubMed Central

Tokar, Erik J.; Benbrahim-Tallaa, Lamia; Ward, Jerold M.; Lunn, Ruth; Sams, Reeder L.; Waalkes, Michael P.

2011-01-01

Inorganic arsenic is a ubiquitous environmental contaminant that has long been considered a human carcinogen. Recent studies raise further concern about the metalloid as a major, naturally occurring carcinogen in the environment. However, during this same period it has proven difficult to provide experimental evidence of the carcinogenicity of inorganic arsenic in laboratory animals and, until recently, there was considered to be a lack of clear evidence for carcinogenicity of any arsenical in animals. More recent work with arsenical methylation metabolites and early life exposures to inorganic arsenic has now provided evidence of carcinogenicity in rodents. Given that tens of millions of people worldwide are exposed to potentially unhealthy levels of environmental arsenic, in vivo rodent models of arsenic carcinogenesis are a clear necessity for resolving critical issues, like mechanisms of action, target tissue specificity, and sensitive subpopulations, and in developing strategies to reduce cancers in exposed human populations. This work reviews the available rodent studies considered relevant to carcinogenic assessment of arsenicals, taking advantage of the most recent review by the International Agency for Research on Cancer (IARC) that has not yet appeared as a full monograph but has been summarized (IARC 2009). Many valid studies show that arsenic can interact with other carcinogens/agents to enhance oncogenesis, and help elucidate mechanisms, and these too are summarized in this review. Finally, this body of rodent work is discussed in light of its impact on mechanisms and in the context of the persistent argument that arsenic is not carcinogenic in animals. PMID:20812815

Decreased Survival of Glioma Patients with Astrocytoma Grade IV (Glioblastoma Multiforme) Associated with Long-Term Use of Mobile and Cordless Phones

PubMed Central

Carlberg, Michael; Hardell, Lennart

2014-01-01

On 31 May 2011 the WHO International Agency for Research on Cancer (IARC) categorised radiofrequency electromagnetic fields (RF-EMFs) from mobile phones, and from other devices that emit similar non-ionising electromagnetic fields, as a Group 2B, i.e., a “possible”, human carcinogen. A causal association would be strengthened if it could be shown that the use of wireless phones has an impact on the survival of glioma patients. We analysed survival of 1678 glioma patients in our 1997–2003 and 2007–2009 case-control studies. Use of wireless phones in the >20 years latency group (time since first use) yielded an increased hazard ratio (HR) = 1.7, 95% confidence interval (CI) = 1.2–2.3 for glioma. For astrocytoma grade IV (glioblastoma multiforme; n = 926) mobile phone use yielded HR = 2.0, 95% CI = 1.4–2.9 and cordless phone use HR = 3.4, 95% CI = 1.04–11 in the same latency category. The hazard ratio for astrocytoma grade IV increased statistically significant per year of latency for wireless phones, HR = 1.020, 95% CI = 1.007–1.033, but not per 100 h cumulative use, HR = 1.002, 95% CI = 0.999–1.005. HR was not statistically significant increased for other types of glioma. Due to the relationship with survival the classification of IARC is strengthened and RF-EMF should be regarded as human carcinogen requiring urgent revision of current exposure guidelines. PMID:25325361

Occupational Burden of Cancer in Korea

PubMed Central

Lee, Hye-Eun; Kang, Seong-Kyu

2010-01-01

Objectives The extent of the occupational cancer burden has rarely been estimated in Korea. The aim of this study is to provide an estimation of the population attributable fraction (PAF) of occupational cancer in Korea. Methods Nine kinds of Group 1 carcinogens addressed by the International Agency for Research on Cancer (IARC) and 7 kinds of cancer were selected for the target carcinogens and diseases, respectively. The prevalence of carcinogen-exposed workers was estimated and correction factors were applied so that the value would be representative of the total population. Data on relative risk (RR) were taken from IARC reports and were compared with the RRs from the studies on Korean workers. The PAF was estimated according to Levin's formula. Results The proportion of the general Korean population exposed to carcinogens was 9.7%. The PAF of total cancer was 1.1% for incident cancer cases and 1.7% for cancer deaths. The PAFs of lung cancer and leukemia were 7.0% and 4.%, respectively. With the RRs reported from Korean studies, the PAF for lung cancer and leukemia were 3.7% and 3.4%, respectively. Conclusion The PAF in this study (1.1%) was lower than that reported in previous studies (2-4%) from developed countries. Considering that only 9 of the 29 kinds of Group 1 carcinogens were included in this study, the PAF might be underestimated. However, because the process of industrialization in Korea differs from that which occurred in other developed countries, 1.1% of the PAF might be appropriate for Korea. PMID:22953164

76 FR 9819 - Agency Information Collection Activities: Proposed Collection; Generic Clearance for the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-22

... International Development. Due to an oversight, those agencies were inadvertently omitted. All Chief Financial Officers Act agencies should have been included in the joint notice. Shelley Metzenbaum, Associate Director...

22 CFR 120.5 - Relation to regulations of other agencies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Relation to regulations of other agencies. 120.5 Section 120.5 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.5 Relation to regulations of other agencies. If an article or service is...

22 CFR 120.5 - Relation to regulations of other agencies.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Relation to regulations of other agencies. 120.5 Section 120.5 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.5 Relation to regulations of other agencies. If an article or service is...

22 CFR 120.5 - Relation to regulations of other agencies.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Relation to regulations of other agencies. 120.5 Section 120.5 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.5 Relation to regulations of other agencies. If an article or service is...

22 CFR 120.5 - Relation to regulations of other agencies.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Relation to regulations of other agencies. 120.5 Section 120.5 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS PURPOSE AND DEFINITIONS § 120.5 Relation to regulations of other agencies. If an article or service is...

Report on the 2015 US Environmental Protection Agency ...

EPA Pesticide Factsheets

Report The 2015 U.S. Environmental Protection Agency (EPA) International Decontamination Research and Development Conference brought together scientists, practitioners, and policymakers related to chemical, biological, and radiological (CBR) remediation.

Benefits of International Collaboration on the International Space Station

NASA Technical Reports Server (NTRS)

Hasbrook, Pete; Robinson, Julie A.; Cohen, Luchino; Marcil, Isabelle; De Parolis, Lina; Hatton, Jason; Shirakawa, Masaki; Karabadzhak, Georgy; Sorokin, Igor V.; Valentini, Giovanni

2017-01-01

The International Space Station is a valuable platform for research in space, but the benefits are limited if research is only conducted by individual countries. Through the efforts of the ISS Program Science Forum, international science working groups, and interagency cooperation, international collaboration on the ISS has expanded as ISS utilization has matured. Members of science teams benefit from working with counterparts in other countries. Scientists and institutions bring years of experience and specialized expertise to collaborative investigations, leading to new perspectives and approaches to scientific challenges. Combining new ideas and historical results brings synergy and improved peer-reviewed scientific methods and results. World-class research facilities can be expensive and logistically complicated, jeopardizing their full utilization. Experiments that would be prohibitively expensive for a single country can be achieved through contributions of resources from two or more countries, such as crew time, up- and down mass, and experiment hardware. Cooperation also avoids duplication of experiments and hardware among agencies. Biomedical experiments can be completed earlier if astronauts or cosmonauts from multiple agencies participate. Countries responding to natural disasters benefit from ISS imagery assets, even if the country has no space agency of its own. Students around the world participate in ISS educational opportunities, and work with students in other countries, through open curriculum packages and through international competitions. Even experiments conducted by a single country can benefit scientists around the world, through specimen sharing programs and publicly accessible "open data" repositories. For ISS data, these repositories include GeneLab, the Physical Science Informatics System, and different Earth data systems. Scientists can conduct new research using ISS data without having to launch and execute their own experiments

International Pesticide Regulations

Science.gov Websites

; Environment Human Health Animal Health Safe Use Practices Food Safety Environment Air Water Soil Wildlife Ingredients Low-Risk Pesticides Organic Pesticide Ingredients Pesticide Incidents Human Exposure Pet Exposure - World Health Organization (WHO) International Agencies: International Websites on Pesticides - OECD

Benefits of International Collaboration on the International Space Station

NASA Technical Reports Server (NTRS)

Hasbrook, Pete; Robinson, Julie A.; Brown Tate, Judy; Thumm, Tracy; Cohen, Luchino; Marcil, Isabelle; De Parolis, Lina; Hatton, Jason; Umezawa, Kazuo; Shirakawa, Masaki;

Funding agencies in low- and middle-income countries: support for knowledge translation.

PubMed

Cordero, Cynthia; Delino, Rachel; Jeyaseelan, L; Lansang, Mary Ann; Lozano, Juan M; Kumar, Shuba; Moreno, Socorro; Pietersen, Merle; Quirino, Jose; Thamlikitkul, Visanu; Welch, Vivian A; Tetroe, Jacqueline; Ter Kuile, Aleida; Graham, Ian D; Grimshaw, Jeremy; Neufeld, Vic; Wells, George; Tugwell, Peter

2008-07-01

The aim was to describe how selected health research funding agencies active in low- and middle-income countries promote the translation of their funded research into policy and practice. We conducted inductive analysis of semi-structured interviews with key informants from a purposive sample of 23 national and international funding agencies that fund health research in Brazil, Colombia, India, the Philippines, South Africa and Thailand. We also surveyed web sites. We found a commitment to knowledge translation in the mandate of 18 of 23 agencies. However, there was a lack of common terminology. Most of the activities were traditional efforts to disseminate to a broad audience, for example using web sites and publications. In addition, more than half (13 of 23) of the agencies encouraged linkage/exchange between researchers and potential users, and 6 of 23 agencies described "pull" activities to generate interest in research from decision-makers. One-third (9 of 23) of funding agencies described a mandate to enhance health equity through improving knowledge translation. Only 3 of 23 agencies were able to describe evaluation of knowledge translation activities. Furthermore, we found national funding agencies made greater knowledge translation efforts when compared to international agencies. Funding agencies are engaged in a wide range of creative knowledge translation activities. They might consider their role as knowledge brokers, with an ability to promote research syntheses and a focus on health equity. There is an urgent need to evaluate the knowledge translation activities of funding agencies.

The effect of multiple primary rules on cancer incidence rates and trends

PubMed Central

Weir, Hannah K.; Johnson, Christopher J.; Ward, Kevin C.; Coleman, Michel P.

2018-01-01

Purpose An examination of multiple primary cancers can provide insight into the etiologic role of genes, the environment, and prior cancer treatment on a cancer patient’s risk of developing a subsequent cancer. Different rules for registering multiple primary cancers (MP) are used by cancer registries throughout the world making data comparisons difficult. Methods We evaluated the effect of SEER and IARC/IACR rules on cancer incidence rates and trends using data from the SEER Program. We estimated age-standardized incidence rate (ASIR) and trends (1975–2011) for the top 26 cancer categories using joinpoint regression analysis. Results ASIRs were higher using SEER compared to IARC/IACR rules for all cancers combined (3 %) and, in rank order, melanoma (9 %), female breast (7 %), urinary bladder (6 %), colon (4 %), kidney and renal pelvis (4 %), oral cavity and pharynx (3 %), lung and bronchus (2 %), and non-Hodgkin lymphoma (2 %). ASIR differences were largest for patients aged 65+ years. Trends were similar using both MP rules with the exception of cancers of the urinary bladder, and kidney and renal pelvis. Conclusions The choice of multiple primary coding rules effects incidence rates and trends. Compared to SEER MP coding rules, IARC/IACR rules are less complex, have not changed over time, and report fewer multiple primary cancers, particularly cancers that occur in paired organs, at the same anatomic site and with the same or related histologic type. Cancer registries collecting incidence data using SEER rules may want to consider including incidence rates and trends using IARC/IACR rules to facilitate international data comparisons. PMID:26809509

KENNEDY SPACE CENTER, FLA. - Lisa Malone, deputy director of External Relations and Business Development at KSC, emcees a ceremony in the Space Station Processing Facility to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Speakers at the ceremony included KSC Director Roy Bridges Jr.; NASA's Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - Lisa Malone, deputy director of External Relations and Business Development at KSC, emcees a ceremony in the Space Station Processing Facility to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Speakers at the ceremony included KSC Director Roy Bridges Jr.; NASA's Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

Regulation of priority carcinogens and reproductive or developmental toxicants

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hooper, K.; LaDou, J.; Rosenbaum, J.S.

In California, 370 carcinogens and 112 reproductive/developmental toxicants have been identified as a result of the State's Safe Drinking Water and Toxic Enforcement Act of 1986. They include pesticides, solvents, metals, industrial intermediates, environmental mixtures, and reactive agents. Occupational, environmental, and consumer product exposures that involve these agents are regulated under the Act. At levels of concern, businesses must provide warnings for and limit discharges of those chemicals. The lists of chemicals were compiled following systematic review of published data, including technical reports from the U.S. Public Health Service--National Toxicology Program (NTP), and evaluation of recommendations from authoritative bodies suchmore » as the International Agency for Research on Cancer (IARC) and the U.S. Environmental Protection Agency (USEPA). Given the large number of chemicals that are carcinogens or reproductive/developmental toxicants, regulatory concerns should focus on those that have high potential for human exposure, e.g., widely distributed or easily absorbed solvents, metals, environmental mixtures, or reactive agents. In this paper, we present a list of 33 potential priority carcinogens and reproductive/developmental toxicants, including alcoholic beverages, asbestos, benzene, chlorinated solvents, formaldehyde, glycol ethers, lead, tobacco smoke, and toluene.« less

Regulation of priority carcinogens and reproductive or developmental toxicants.

PubMed

Hooper, K; LaDou, J; Rosenbaum, J S; Book, S A

1992-01-01

In California, 370 carcinogens and 112 reproductive/developmental toxicants have been identified as a result of the State's Safe Drinking Water and Toxic Enforcement Act of 1986. They include pesticides, solvents, metals, industrial intermediates, environmental mixtures, and reactive agents. Occupational, environmental, and consumer product exposures that involve these agents are regulated under the Act. At levels of concern, businesses must provide warnings for and limit discharges of those chemicals. The lists of chemicals were compiled following systematic review of published data, including technical reports from the U.S. Public Health Service--National Toxicology Program (NTP), and evaluation of recommendations from authoritative bodies such as the International Agency for Research on Cancer (IARC) and the U.S. Environmental Protection Agency (USEPA). Given the large number of chemicals that are carcinogens or reproductive/developmental toxicants, regulatory concerns should focus on those that have high potential for human exposure, e.g., widely distributed or easily absorbed solvents, metals, environmental mixtures, or reactive agents. In this paper, we present a list of 33 potential priority carcinogens and reproductive/developmental toxicants, including alcoholic beverages, asbestos, benzene, chlorinated solvents, formaldehyde, glycol ethers, lead, tobacco smoke, and toluene.

Policies and Procedures for Foreign Exchange Agencies. First Edition.

ERIC Educational Resources Information Center

Hartman, Donald D.

The guide details the policy of the Jefferson County (Alabama) Board of Education policy concerning international exchange of students (travel both to and from United States) in elementary and secondary grades. The first section specifies the standards by which the county will evaluate all international exchange agencies concerning structure,…

21 CFR 516.123 - Informal conferences regarding agency administrative actions.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Director of the Center for Veterinary Medicine or his or her designee, excluding the Director of the Office... response to that decision. (g) Internal agency review of a decision must be based on the information in the..., the matter will be returned to the appropriate lower level in the agency for reevaluation based on the...

21 CFR 516.123 - Informal conferences regarding agency administrative actions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Director of the Center for Veterinary Medicine or his or her designee, excluding the Director of the Office... response to that decision. (g) Internal agency review of a decision must be based on the information in the..., the matter will be returned to the appropriate lower level in the agency for reevaluation based on the...

21 CFR 516.123 - Informal conferences regarding agency administrative actions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Director of the Center for Veterinary Medicine or his or her designee, excluding the Director of the Office... response to that decision. (g) Internal agency review of a decision must be based on the information in the..., the matter will be returned to the appropriate lower level in the agency for reevaluation based on the...

A Model for Study of Teacher Agency for Social Justice

ERIC Educational Resources Information Center

Pantic, Nataša

2015-01-01

Internationally teachers are called upon to act as agents of change. However, there is little clarity about the kind of change teachers are expected to contribute to and even less empirical evidence about the ways teacher agency operates in schools and beyond. Empirical analyses of teacher agency require a clear articulation of the purpose and…

78 FR 53504 - Internal Revenue Service

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-29

... DEPARTMENT OF THE TREASURY Internal Revenue Service Proposed Collection; Comment Request for Revenue Procedure 2007-37 AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice and request for... Gerald J. Shields at Internal Revenue Service, room 6129, 1111 Constitution Avenue NW., Washington, DC...

Evaluation of the international standardized 24-h dietary recall methodology (GloboDiet) for potential application in research and surveillance within African settings.

PubMed

Aglago, Elom Kouassivi; Landais, Edwige; Nicolas, Geneviève; Margetts, Barrie; Leclercq, Catherine; Allemand, Pauline; Aderibigbe, Olaide; Agueh, Victoire Damienne; Amuna, Paul; Annor, George Amponsah; El Ati, Jalila; Coates, Jennifer; Colaiezzi, Brooke; Compaore, Ella; Delisle, Hélène; Faber, Mieke; Fungo, Robert; Gouado, Inocent; El Hamdouchi, Asmaa; Hounkpatin, Waliou Amoussa; Konan, Amoin Georgette; Labzizi, Saloua; Ledo, James; Mahachi, Carol; Maruapula, Segametsi Ditshebo; Mathe, Nonsikelelo; Mbabazi, Muniirah; Mirembe, Mandy Wilja; Mizéhoun-Adissoda, Carmelle; Nzi, Clement Diby; Pisa, Pedro Terrence; El Rhazi, Karima; Zotor, Francis; Slimani, Nadia

2017-06-19

Collection of reliable and comparable individual food consumption data is of primary importance to better understand, control and monitor malnutrition and its related comorbidities in low- and middle-income countries (LMICs), including in Africa. The lack of standardised dietary tools and their related research support infrastructure remains a major obstacle to implement concerted and region-specific research and action plans worldwide. Citing the magnitude and importance of this challenge, the International Agency for Research on Cancer (IARC/WHO) launched the "Global Nutrition Surveillance initiative" to pilot test the use of a standardized 24-h dietary recall research tool (GloboDiet), validated in Europe, in other regions. In this regard, the development of the GloboDiet-Africa can be optimised by better understanding of the local specific methodological needs, barriers and opportunities. The study aimed to evaluate the standardized 24-h dietary recall research tool (GloboDiet) as a possible common methodology for research and surveillance across Africa. A consultative panel of African and international experts in dietary assessment participated in six e-workshop sessions. They completed an in-depth e-questionnaire to evaluate the GloboDiet dietary methodology before and after participating in the e-workshop. The 29 experts expressed their satisfaction on the potential of the software to address local specific needs when evaluating the main structure of the software, the stepwise approach for data collection and standardisation concept. Nevertheless, additional information to better describe local foods and recipes, as well as particular culinary patterns (e.g. mortar pounding), were proposed. Furthermore, food quantification in shared-plates and -bowls eating situations and interviewing of populations with low literacy skills, especially in rural settings, were acknowledged as requiring further specific considerations and appropriate solutions. An overall

Overstory and Understory CO2 and Energy Fluxes of a Black Spruce Forest in Interior Alaska

NASA Astrophysics Data System (ADS)

Ikawa, H.; Nakai, T.; Busey, R.; Kim, Y.; Kobayashi, H.; Nagai, S.; Ueyama, M.; Saito, K.; Suzuki, R.; Hinzman, L. D.

2014-12-01

Eddy covariance techniques were used to quantify understory contributions to carbon and energy balances, and to evaluate the environmental responses of the overstory and understory at a black spruce forest in interior Alaska. Net ecosystem productivity (NEP), gross primary productivity (GPP), ecosystem respiration (RE), sensible heat flux (H), and latent heat flux (LE) were estimated for the ecosystem (subscripted by 'eco'), canopy (subscripted by 'cano') and forest floor (subscripted by 'floor') based on canopy gap fraction and footprint analyses for 3 years, 2011 - 2013. Fluxes per unit land surface area of black spruce overstory (subscripted by 'b') and that of understory (subscripted by 'u') were also evaluated their ecophysiological responses to micrometeorological environments. Overall, NEPfloor, GPPfloor, REfloor and LEfloor represented 60 (37, growing season in parenthesis) %, 47 (51) %, 47 (54) %, and 75 (76) % of NEPeco, GPPeco, REeco, and LEeco, respectively with the average canopy gap fraction of 0.52 (± 0.073 SD). The year, 2013 was characterized by high air temperature and vapor pressure deficit (VPD) during the growing season. The high temperature and VPD particularly reduced understory NEP and their growth inferred by low green excessive index (GEI), which was correlated to GPPu more strongly than GPPb. LEu linearly increased with vapor pressure deficit (VPD) whereas LEb was insensitive to VPD. Future warming and drying expected in the boreal forest will increase understory evapotranspiration disproportionately to that of black spruce and likely decrease the production of the current understory community. Acknowledgments This study was supported by the Japan Aerospace Exploration Agency (JAXA) and the JAMSTEC-IARC Collaboration Study, with funding provided by the Japan Agency for Marine-Earth Science and Technology (JAMSTEC) to the International Arctic Research Center (IARC). The Polar Geospatial Center, University of Minnesota provided the Quick

The ERS Research Agency: the beginning.

PubMed

Soriano, Joan B; Paton, James; Martin Burrieza, Fernando; Bill, Werner; Pannetier, Carine; Aliberti, Stefano; Adcock, Ian M; Wagers, Scott; Migliori, Giovanni Battista

2016-04-01

There is at the current time a significant opportunity for the ERS to leverage its experience and reputation as an international umbrella organisation to promote high-quality, multinational respiratory research with the goal of improving the health of respiratory patients. This editorial proposes a model for the role and structure of an ERS Research Agency. It is based upon research, implicit knowledge and explicit feedback from ERS members and selected external individuals and organisations.As with any new endeavour there are challenges and threats. Building a Research Agency will be a major undertaking that will require significant organisational planning, resources, effort and commitment.Organisations with multiple stakeholders tend to have a status quo inertia that has to be overcome for any significant new endeavour. The ERS Research Agency could be an investment in the future of respiratory research.

Exposure to hazardous substances in a standard molecular biology laboratory environment: evaluation of exposures in IARC laboratories.

PubMed

Chapot, Brigitte; Secretan, Béatrice; Robert, Annie; Hainaut, Pierre

2009-07-01

Working in a molecular biology laboratory environment implies regular exposure to a wide range of hazardous substances. Several recent studies have shown that laboratory workers may have an elevated risk of certain cancers. Data on the nature and frequency of exposures in such settings are scanty. The frequency of use of 163 agents by staff working in molecular biology laboratories was evaluated over a period of 4 years by self-administered questionnaire. Of the agents listed, ethanol was used by the largest proportion of staff (70%), followed by ethidium bromide (55%). Individual patterns of use showed three patterns, namely (i) frequent use of a narrow range of products, (ii) occasional use of a wide range of products, and (iii) frequent and occasional use of an intermediate range of products. Among known or suspected carcinogens (International Agency for Research on Cancer Group 1 and 2A, respectively), those most frequently used included formaldehyde (17%), oncogenic viruses (4%), and acrylamide (32%). The type of exposure encountered in research laboratories is extremely diverse. Few carcinogenic agents are used frequently but many laboratory workers may be exposed occasionally to known human carcinogens. In addition, many of the chemicals handled by staff represent a health hazard. The results enabled the staff physician to develop an individual approach to medical surveillance and to draw a personal history of occupational exposures for laboratory staff.

75 FR 29818 - Internal Revenue Service

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-27

... DEPARTMENT OF THE TREASURY Internal Revenue Service Advisory Group to the Internal Revenue Service Tax Exempt and Government Entities Division (TE/GE); Meeting AGENCY: Internal Revenue Service (IRS..., Director, TE/GE Communications and Liaison; 1111 Constitution Ave., NW.; SE:T:CL--Penn Bldg; Washington, DC...

International cooperation in water resources

USGS Publications Warehouse

Jones, J.R.; Beall, R.M.; Giusti, E.V.

1979-01-01

Advancements in hydrology proceeded slowly until the late 1800's when new ventures created a surge of interest and accomplishment. Progress waned again until the middle 20th century when an International Hydrological Decade was conceived, eventually receiving wide multinational support from governmental agencies and nongovernmental institutions. Organized by UNESCO, the Decade program was launched January 1, 1965. Participation included 107 nations, six United Nations agencies, and more than a dozen international scientific organizations. The initial program emphasized scientific research, and international cooperation; the second half of the Decade, emphasized technical assistance and technology transfer, largerly through education, training and demonstration. The success of the Decade led to the establishment of the International Hydrological Program, again under the aegis of UNESCO, to continue the work of the Decade indefinitely. The five major program activities, now involving about 90 countries and several international organizations, include: the scientific program, the promotion of education and training, the enhancement of information exchange, support of technical assistance, and the enlargement of regional cooperation. A significant amount of activity related to hydrological data networks and forecasting is carried on in an Operational Hydrology Programme by the WMO, chiefly through its Commission for Hydrology. Other international governmental organizations with a strong interest in water include the UN, the UN Development Programme, the FAO, the WHO, the International Atomic Energy Agency, the UN Environment Programme, the International Standardization Organization, and developmental institutions such as the World Bank. The specialized interests of researchers outside of the governmental structure, are met through association in various scientific and technical organizations which are world wide in scope and membership. Notwithstanding a sometimes

Metacognition of agency and theory of mind in adults with high functioning autism.

PubMed

Zalla, Tiziana; Miele, David; Leboyer, Marion; Metcalfe, Janet

2015-01-01

We investigated metacognition of agency in adults with high functioning autism or Asperger Syndrome (HFA/AS) using a computer task in which participants moved the mouse to get the cursor to touch the downward moving X's and avoid the O's. They were then asked to make judgments of performance and judgments of agency. Objective control was either undistorted, or distorted by adding turbulence (i.e., random noise) or a time Lag between the mouse and cursor movements. Participants with HFA/AS used sensorimotor cues available in the turbulence and lag conditions to a lesser extent than control participants in making their judgments of agency. Furthermore, the failure to use these internal diagnostic cues to their own agency was correlated with decrements in a theory of mind task. These findings suggest that a reduced sensitivity to veridical internal cues about the sense of agency is related to mentalizing impairments in autism. Copyright © 2014 Elsevier Inc. All rights reserved.

International Space Station (ISS)

NASA Image and Video Library

2001-10-23

Carrying out a flight program for the French Space Agency (CNES) under a commerial contract with the Russian Aviation and Space Agency, a Russian Soyuz spacecraft approaches the International Space Station (ISS) delivering a crew of three for an eight-day stay. Aboard the craft are Commander Victor Afanasyev, Flight Engineer Konstantin Kozeev, both representing Rosaviakosmos, and French Flight Engineer Claudie Haignere.

International Space Station (ISS)

NASA Image and Video Library

2001-10-23

Carrying out a flight program for the French Space Agency (CNES) under a commercial contract with the Russian Aviation and Space Agency, a Russian Soyuz spacecraft approaches the International Space Station (ISS), delivering a crew of three for an eight-day stay. Aboard the craft are Commander Victor Afanasyev, Flight Engineer Konstantin Kozeev, both representing Rosaviakosmos, and French Flight Engineer Claudie Haignere.

Internal Audit Manual.

DTIC Science & Technology

1985-11-01

multilocation audits because of the significant amount of planning, resources, and time they require, coordination of all review efforts shall be the...similar to the multilocation audits of the internal audit activities. f. The Military Department audit agencies and the Military Department criminal...34 -.° -.- . . °- . .. ?.. . .. . .. .. . .. . .. . .. . .. .. . .. . .. . .. .. . . .. :2 DOD 7600.7-M DEPARTMENT OF DEFENSE( %INTERNAL AUDIT ~MANUAL Jq- OFFICE OF L- INSPECTOR GENERAL

Female breast cancer incidence and mortality in Mexico, 2000-2010.

PubMed

Anaya-Ruiz, Maricruz; Vallejo-Ruiz, Veronica; Flores-Mendoza, Lilian; Perez-Santos, Martin

2014-01-01

The objective of this study was to investigate the recent incidence and mortality trends for breast cancer in Mexican females. Data between 2000 and 2010 from the Department of Epidemiology of the Ministry of Health, and International Agency for Research on Cancer (IARC) were analyzed. Age-standardized rates (ASRs) and annual percent changes (APCs) were calculated. The absolute incidence and mortality rates of breast cancer increased: 3,726 and 4,615 in 2000 to 8,545 and 4,966 in 2010, respectively. Incidence increased over time in all age groups tested, the 60-64 age group had the highest ASR (57.4 per 100,000 women in 2010), while the 20-44 age group had the lowest ASR (12.3 in 2010). The results show that incidence of breast cancer has increased in Mexico during last one decade, especially among older women, while the downturn observed in mortality mainly reflects improved survival as a result of earlier diagnosis and better cancer treatment.

Pharmacokinetics and Biodistribution of the Illegal Food Colorant Rhodamine B in Rats.

PubMed

Cheng, Yung-Yi; Tsai, Tung-Hu

2017-02-08

The International Agency for Research on Cancer (IARC) demonstrated rhodamine B as a potential carcinogen in 1978. Nevertheless, rhodamine B has been illegally used as a colorant in food in many countries. Few pharmacokinetic and toxicological investigations have been performed since the first pharmacokinetic study on rhodamine B in 1961. The aims of this study were to develop a simple and sensitive high-performance liquid chromatography method with fluorescence detection for the quantitative detection of rhodamine B in the plasma and organs of rats and to estimate its pharmacokinetics and biodistribution. The results demonstrated that the oral bioavailabilities of rhodamine B were 28.3 and 9.8% for the low-dose and high-dose exposures, respectively. Furthermore, rhodamine B was highly accumulated in the liver and, to a lesser extent, the kidney, but was undetectable in the brain. These results provide useful information for improving the pharmacokinetics and biodistribution of rhodamine B, supporting additional food safety evaluations.

An overview of the toxicology and toxicokinetics of fusarenon-X, a type B trichothecene mycotoxin.

PubMed

Aupanun, Sawinee; Poapolathep, Saranya; Giorgi, Mario; Imsilp, Kanjana; Poapolathep, Amnart

2017-01-20

Fusarenon-X (FX) is a type B trichothecene mycotoxin that is frequently observed along with deoxynivalenol (DON) and nivalenol (NIV) in agricultural commodities. This review aims to give an overview of the literature concerning the toxicology and toxicokinetics of FX. FX is primarily found in cereals grown in temperate regions, but it can also be found worldwide because of the global transport of products. The major toxicity of FX occurs through inhibition of protein synthesis, followed by the disruption of DNA synthesis. Moreover, FX has also been shown to induce apoptosis in in vitro and in vivo studies. The targets of FX are organs containing actively proliferating cells, such as the thymus, spleen, skin, small intestine, testes and bone marrow. FX causes immunosuppression, intestinal malabsorption, developmental toxicity and genotoxicity. In addition, sufficient evidence of carcinogenicity in experimental animals is currently lacking, and the International Agency for Research on Cancer (IARC) classifies it as a group 3 carcinogen.

Second International Microgravity Laboratory (IML-2)

NASA Technical Reports Server (NTRS)

Snyder, Robert S. (Compiler)

1997-01-01

This report highlights the scientific and engineering accomplishments achieved during the 14-day Second International Microgravity Laboratory (IML-2) mission. The mission, managed by the National Aeronautics and Space Administration's Marshall Space Flight Center in Huntsville, Alabama, laid the groundwork for broader international partnerships and scientific alliances. Five other space agencies joined NASA on the mission: the Canadian Space Agency (CSA), the European Space Agency (ESA), the French Space Agency (CNES), the German Space Agency (DARA), and the National Space Development Agency of Japan (NASDA). For the mission, microgravity and life sciences investigations were completed inside Spacelab by a crew working around the clock. The report foreword and introduction describe the mission and the facilities used for IML-2. By the end of the mission, hundreds of primary and secondary experiments were completed. With the help of the principal investigators, most of the primary investigations and some of the co-investigations are described in this document. The lead report authors are cited at the beginning of each experiment description The remainder of the description includes the experiment objectives, flight activities postflight analysis, conclusions, illustrations, and references for further research. The major scientific accomplishments of each investigation are highlighted.

Benefits of International Collaboration on the International Space Station

NASA Technical Reports Server (NTRS)

Robinson, Julie A.; Hasbrook, Pete; Tate Brown, Judy; Thumm, Tracy; Cohen, Luchino; Marcil, Isabelle; De Parolis, Lina; Hatton, Jason; Umezawa, Kazuo; Shirakawa, Masaki;

Explaining the enforcement gap in China: local government support and internal agency obstacles as predictors of enforcement actions in Guangzhou.

PubMed

Lo, Carlos Wing-Hung; Fryxell, Gerald E; van Rooij, Benjamin; Wang, Wei; Honying Li, Pansy

2012-11-30

This study investigates how local government support for enforcement and internal agency obstacles explain the enforcement gap in Guangzhou, China. It was found that agency obstacles associated with insufficient resources and job ambiguity, in particular, affect enforcement officials' perceptions of enforcement difficulty. Somewhat more surprisingly, however, local government support was not found to be a significant predictor of these perceptions. In addition, this study identified four significant relationships associated with specific enforcement actions. First and second, perceptions of enforcement difficulty appear to lead to fewer inspections, but also have a weak positive effect on the frequency of fines levied. Third, poor coordination within the bureau was found to be associated with fewer violations being processed. Fourth, and contrary to expectations, local government support was found to suppress the frequency of inspections while having no significant effect on violations or fines. Overall, these findings suggest that increased local government support for the enforcement of environmental regulation in China may not necessarily lead to more rigorous enforcement, at least if enforcement rigor is measured in terms of inspections, citations and fines. Copyright © 2012 Elsevier Ltd. All rights reserved.

Space agencies' scientific roadmaps need harmonisation and reegular re-assessment

NASA Astrophysics Data System (ADS)

Worms, Jean-Claude; Culhane, J. Leonard; Walter, Nicolas; Swings, Jean-Pierre; Detsis, Emmanouil

The need to consider international collaboration in the exploration of space has been recognised since the dawn of the space age in 1957. Since then, international collaboration has been the main operational working mode amongst space scientists the world over, setting aside national pre-eminence and other political arguments. COSPAR itself was created as a tool for scientists to maintain the dialogue at the time of the cold war. Similarly the inherent constraints of the field (cost, complexity, time span) have led space agencies to try and coordinate their efforts. As a result many - if not all - of the key space science missions since the 60’s have been collaborative by nature. Different collaboration models have existed with varying success, and the corresponding lessons learned have been assessed through various fora and reports. For various reasons whose scope has broadened since that time (use of space in other domains such as Earth observation, telecommunication and navigation; emergence of commercial space activities; increased public appeal and capacity to motivate the young generation to engage into related careers), the importance of international collaboration in space has never faltered and coordination among spacefaring nations has become the norm. However programme harmonisation is often found to be lacking, and duplication of efforts sometimes happens due to different planning and decision procedures, programmatic timelines or budgetary constraints. Previous studies, in particular by the European ESSC-ESF, with input from the US NAS-SSB, advocated the need to establish a coordinating body involving major space agencies to address these coordination issues in a systematic and harmonious way. Since then and in line with this recommendation, the International Space Exploration Coordination Group (ISECG) of 14 space agencies was created in 2007 and published a first roadmap to advance a “Global Exploration Strategy”. ISECG is non-binding though

How health technology assessment agencies address the issue of unpublished data.

PubMed

Kreis, Julia; Panteli, Dimitra; Busse, Reinhard

2014-01-01

Reporting bias potentially threatens the validity of results in health technology assessment (HTA) reports. Our study aimed to explore policies and practices of HTA agencies regarding strategies to include previously unpublished data in their assessments, focusing on requests to industry for unpublished data. We included international HTA agencies with publicly available methods papers as well as HTA reports. From the methods papers and recent reports we extracted information on requests to industry and on searches in trial registries, regulatory authority Web sites and for conference abstracts. Eighteen HTA agencies and seventy-three reports were included. Agencies' methods papers showed variability regarding requests to industry (requests are routinely carried out in seven cases, not mentioned in six, at the discretion of HTA authors in three, and based on manufacturer applications in two), which were reflected in the reports investigated. As reporting of requests was limited, it often remained unclear whether unpublished data had been received. Searches in trial registries, at regulatory authorities or for conference abstracts are described as a routine or optional part of the search strategy in the methods papers of 9, 11, and 8 included agencies, respectively. A total of 52 percent, 39 percent, and 16 percent of reports described searches in trial registries, at regulatory agencies, and hand searching of conference proceedings. International HTA agencies currently differ considerably in their efforts to address the issue of unpublished data. Requests to industry may constitute one strategy to access and include unpublished data, while agencies can learn from each other concerning successful practice.

Inequalities and Agencies in Workplace Learning Experiences: International Student Perspectives

ERIC Educational Resources Information Center

Wall, Tony; Tran, Ly Thi; Soejatminah, Sri

2017-01-01

National systems of vocational education and training around the globe are facing reform driven by quality, international mobility, and equity. Evidence suggests that there are qualitatively distinctive challenges in providing and sustaining workplace learning experiences to international students. However, despite growing conceptual and empirical…

The commodification of international migration: findings from Thailand.

PubMed

Jones, H; Pardthaisong, T

1999-01-01

"The organisation of international contract-labour migration within Asia has been increasingly dominated by commercial agencies acting as intermediaries between workers and foreign employers. The principles underpinning the gatekeeping role of such agencies in the East Asian migration system are examined. A consideration of the international labour recruitment system in Thailand is based on survey work among agents, community leaders and recently returned migrants." excerpt

International nuclear waste management fact book

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abrahms, C W; Patridge, M D; Widrig, J E

1995-11-01

The International Nuclear Waste Management Fact Book has been compiled to provide current data on fuel cycle and waste management facilities, R and D programs, and key personnel in 24 countries, including the US; four multinational agencies; and 20 nuclear societies. This document, which is in its second year of publication supersedes the previously issued International Nuclear Fuel Cycle Fact Book (PNL-3594), which appeared annually for 12 years. The content has been updated to reflect current information. The Fact Book is organized as follows: National summaries--a section for each country that summarizes nuclear policy, describes organizational relationships, and provides addressesmore » and names of key personnel and information on facilities. International agencies--a section for each of the international agencies that has significant fuel cycle involvement and a list of nuclear societies. Glossary--a list of abbreviations/acronyms of organizations, facilities, and technical and other terms. The national summaries, in addition to the data described above, feature a small map for each country and some general information that is presented from the perspective of the Fact Book user in the US.« less

Final Tier 2 Environmental Impact Statement for International Space Station

NASA Technical Reports Server (NTRS)

1996-01-01

The Final Tier 2 Environmental Impact Statement (EIS) for the International Space Station (ISS) has been prepared by the National Aeronautics and Space Administration (NASA) and follows NASA's Record of Decision on the Final Tier 1 EIS for the Space Station Freedom. The Tier 2 EIS provides an updated evaluation of the environmental impacts associated with the alternatives considered: the Proposed Action and the No-Action alternative. The Proposed Action is to continue U.S. participation in the assembly and operation of ISS. The No-Action alternative would cancel NASA!s participation in the Space Station Program. ISS is an international cooperative venture between NASA, the Canadian Space Agency, the European Space Agency, the Science and Technology Agency of Japan, the Russian Space Agency, and the Italian Space Agency. The purpose of the NASA action would be to further develop human presence in space; to meet scientific, technological, and commercial research needs; and to foster international cooperation.

Draft Tier 2 Environmental Impact Statement for International Space Station

NASA Technical Reports Server (NTRS)

1995-01-01

The Draft Tier 2 Environmental Impact Statement (EIS) for the International Space Station (ISS) has been prepared by the National Aeronautics and Space Administration (NASA) and follows NASA's Record of Decision on the Final Tier 1 EIS for the Space Station Freedom. The Tier 2 EIS provides an updated evaluation of the environmental impacts associated with the alternatives considered: the Proposed Action and the No-Action alternative. The Proposed Action is to continue U.S. participation in the assembly and operation of ISS. The No-Action alternative would cancel NASA's participation in the Space Station Program. ISS is an international cooperative venture between NASA, the Canadian Space Agency, the European Space Agency, the Science and Technology Agency of Japan, the Russian Space Agency, and the Italian Space Agency. The purpose of the NASA action would be to further develop a human presence in space; to meet scientific, technological, and commercial research needs; and to foster international cooperation.

International Space Station (ISS)

NASA Image and Video Library

2001-10-23

A Russian Soyuz spacecraft undocks from the International Space Station (ISS) with its crew of three ending an eight-day stay. Aboard the craft are Commander Victor Afanasyev, Flight Engineer Konstantin Kozeev, both representing Rosaviakosmos, and French Flight Engineer Claudie Haignere. Their mission was to carry out a flight program for the French Space Agency (CNES) under a commercial contract with the Russian Aviation and Space Agency.

International Space Station (ISS)

NASA Image and Video Library

2001-10-23

A Russian Soyuz spacecraft departs from the International Space Station (ISS) with its crew of three ending an eight-day stay. Aboard the craft are Commander Victor Afanasyev, Flight Engineer Konstantin Kozeev, both representing Rosaviakosmos, and French Flight Engineer Claudie Haignere. Their mission was to carry out a flight program for the French Space Agency (CNES) under a commercial contract with the Russian Aviation and Space Agency.

The vulnerable do-gooders: security strategies of German aid agencies.

PubMed

Schneiker, Andrea

2013-04-01

Humanitarian and development agencies have confronted growing insecurity in some of the regions in which they work over the course of the past decade. Consequently, aid agencies are changing their approach to security issues. Compared to aid agencies from other countries, especially the United Kingdom and the United States, German aid agencies have been relatively slow to adopt security measures. In addition, the security measures they have selected differ from one agency to another, even in comparable security contexts. The literature on organisational learning helps to explain these differences. The findings show that external and internal organisational factors influence an aid agency's choice of a particular security measure. The different responses of German aid agencies to the changing security environment demonstrate that security measures are not only influenced by an organisation's identity but also can be a way for them to demonstrate their identity and thereby distinguish themselves from other actors that deliver aid. © 2013 The Author(s). Journal compilation © Overseas Development Institute, 2013.

Handbook of Information Relevant to Manpower Agencies: A Compilation of Practice Principles and Strategies for Manpower Operations.

ERIC Educational Resources Information Center

Erfurt, John C.; And Others

Concepts of internal agency structure and operations, agency-company relations, and agency-enrollee relations, with recommendations for their implementation, form the three main sections of this handbook developed for manpower agency administrators, supervisory staffs and program planners. It is designed to aid those who organize and develop…

20 CFR 402.95 - Exemption five for withholding records: Internal memoranda.

Code of Federal Regulations, 2010 CFR

2010-04-01

... memoranda. This exemption covers internal government communications and notes that fall within a generally recognized evidentiary privilege. Internal government communications include an agency's communications with... communications are for a purpose similar to the purpose of privileged intra-agency communications. Some of the...

16 CFR 0.20 - Office of International Affairs.

Code of Federal Regulations, 2010 CFR

2010-01-01

... consumer protection aspects of trade fora and negotiations, such as the U.S. inter-agency delegations... international antitrust, international consumer protection, and international technical assistance. OIA is... advice to the Bureaus of Competition and Consumer Protection with regard to the international aspects of...

78 FR 63873 - Minimum Internal Control Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-25

... Internal Control Standards AGENCY: National Indian Gaming Commission, Interior. ACTION: Final rule. SUMMARY: The National Indian Gaming Commission (NIGC) amends its minimum internal control standards for Class... Internal Control Standards. 64 FR 590. The rule added a new part to the Commission's regulations...

Health-related biotechnology transfer to Africa: principal-agency relationship issues.

PubMed

Kirigia, J M; Muthuri, L K; Kirigia, D G

2007-01-01

The aim of this paper is to stimulate debate on the agency (principal-agent) in health-related biotechnology research. It attempts to answer the following questions: What is health-related biotechnology and biotechnology research? What is an agency? What factors are likely to undermine the principal's capacity to exercise informed consent? When might the principal-agency problem arise? How could the agency in biotechnology transfer be strengthened in Sub-Saharan Africa (SSA)? The transfer of health-related biotechnology to SSA ought to be preceded by research to ascertain the effectiveness of such technologies on population health. In that process, the national ethical review committee (REC), as an agent of every human research subject (principal), ought to ensure that international principles (e.g. beneficence, non-malfeasance, autonomy, justice, dignity, truthfulness and honesty) for human experimentation are observed by biotechnology researchers in order to satisfy moral, ethical and legal requirements. The key factors that undermine principals' sovereignty in exercising their right to informed consent to participate in biotechnology trials are discussed. The paper ends with a list of activities that can strengthen the agency, e.g. legislative requirement that all health-related biotechnology transfer should be preceded by rigorous evaluation; continuous update of the agents knowledge of the contents of the international ethical guidelines; and education of potential and actual principals on their human rights; among others.

An empirical typology of private child and family serving agencies.

PubMed

Chuang, Emmeline; Collins-Camargo, Crystal; McBeath, Bowen; Wells, Rebecca; Bunger, Alicia

2014-03-01

Differences in how services are organized and delivered can contribute significantly to variation in outcomes experienced by children and families. However, few comparative studies identify the strengths and limitations of alternative delivery system configurations. The current study provides the first empirical typology of private agencies involved with the formal child welfare system. Data collected in 2011 from a national sample of private agencies were used to classify agencies into five distinct groups based on internal management capacity, service diversification, integration, and policy advocacy. Findings reveal considerable heterogeneity in the population of private child and family serving agencies. Cross-group comparisons suggest that differences in agencies' strategic and structural characteristics correlated with agency directors' perceptions of different pressures in their external environment. Future research can use this typology to better understand local service systems and the extent to which different agency strategies affect performance and other outcomes. Such information has implications for public agency contracting decisions and could inform system-level assessment and planning of services for children and families.

Epidemiology of virus infection and human cancer.

PubMed

Chen, Chien-Jen; Hsu, Wan-Lun; Yang, Hwai-I; Lee, Mei-Hsuan; Chen, Hui-Chi; Chien, Yin-Chu; You, San-Lin

2014-01-01

The International Agency for Research on Cancer (IARC) has comprehensively assessed the human carcinogenicity of biological agents. Seven viruses including Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C virus (HCV), Kaposi's sarcoma herpes virus (KSHV), human immunodeficiency virus, type-1 (HIV-1), human T cell lymphotrophic virus, type-1 (HTLV-1), and human papillomavirus (HPV) have been classified as Group 1 human carcinogens by IARC. The conclusions are based on the findings of epidemiological and mechanistic studies. EBV, HPV, HTLV-1, and KSHV are direct carcinogens; HBV and HCV are indirect carcinogens through chronic inflammation; HIV-1 is an indirect carcinogen through immune suppression. Some viruses may cause more than one cancer, while some cancers may be caused by more than one virus. However, only a proportion of persons infected by these oncogenic viruses will develop specific cancers. A series of studies have been carried out to assess the viral, host, and environmental cofactors of EBV-associated nasopharyngeal carcinoma, HBV/HCV-associated hepatocellular carcinoma, and HPV-associated cervical carcinoma. Persistent infection and high viral load are important risk predictors of these virus-caused cancers. Risk calculators incorporating host and viral factors have also been developed for the prediction of long-term risk of hepatocellular carcinoma. These risk calculators are useful for the triage and clinical management of infected patients. Both clinical trials and national programs of immunization or antiviral therapy have demonstrated a significant reduction in the incidence of cancers caused by HBV, HCV, and HPV. Future researches on gene-gene and gene-environment interaction of oncogenic viruses and human host are in urgent need.

77 FR 38802 - Proposed CERCLA Administrative Cost Recovery Settlement; Standex International Corporation

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-29

... Settlement; Standex International Corporation AGENCY: Environmental Protection Agency. ACTION: Notice; request for public comment. SUMMARY: Notice is hereby given of a proposed administrative settlement for... following settling party: Standex International Corporation. The settlement requires the settling party to...

5 CFR 352.304 - International organizations covered.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false International organizations covered. 352... REEMPLOYMENT RIGHTS Detail and Transfer of Federal Employees to International Organizations § 352.304 International organizations covered. (a) An agency may detail or transfer an employee under this subpart...

78 FR 11793 - Minimum Internal Control Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-20

... Internal Control Standards AGENCY: National Indian Gaming Commission. ACTION: Proposed rule. SUMMARY: The National Indian Gaming Commission (NIGC) proposes to amend its minimum internal control standards for Class... NIGC published a final rule in the Federal Register called Minimum Internal Control Standards. 64 FR...

77 FR 32444 - Minimum Internal Control Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-01

... Internal Control Standards AGENCY: National Indian Gaming Commission. ACTION: Proposed rule. SUMMARY: The National Indian Gaming Commission (NIGC) proposes to amend its minimum internal control standards for Class... the Federal Register called Minimum Internal Control Standards. 64 FR 590. The rule added a new part...

Mexican Space Agency and NASA Agreement

NASA Image and Video Library

2013-03-18

NASA Administrator Charles Bolden (center) presents Dr. Francisco Javier Mendieta Jimenez, Director General of the Mexican Space Agency, a NASA montage in honor of the Reimbursable Space Act Agreement (RSAA) signed between the two agencies, Monday, March 18, 2013 at NASA Headquarters in Washington. Leland Melvin (right), NASA Associate Administrator for Education looks on. The International Internship Program is a pilot program developed at NASA which will provide and avenue for non-US students to come to NASA for an internship. US students will be paired with a foreign student to work on a NASA research project under the guidance of a mentor. This is the first NASA-Mexico agreement signed. Photo Credit: (NASA/Carla Cioffi)

Crisis Communication Practices at an International Relief Agency

ERIC Educational Resources Information Center

Genova, Gina L.

2006-01-01

When a disaster strikes, the affected population relies upon the swift response and aid rendered by relief organizations such as the California-based Direct Relief International. Since 1948, Direct Relief's mission has been to provide essential material resources to locally run health programs in areas affected by natural disasters, wars, and…

International Business Program Needs Assessment.

ERIC Educational Resources Information Center

Oakland Community Coll., Farmington, MI. Office of Institutional Planning and Analysis.

In 1991, a study was conducted by Oakland Community College to evaluate the need for a proposed International Business program. General information was obtained from a literature search, various governmental and public interest agencies involved in international business, and other southeast Michigan community colleges. In addition, a survey was…

International Atomic Energy Agency specialists meeting on experience in ageing, maintenance, and modernization of instrumentation and control systems for improving nuclear power plant availability

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1993-10-01

This report presents the proceedings of the Specialist`s Meeting on Experience in Aging, Maintenance and Modernization of Instrumentation and Control Systems for Improving Nuclear Power Plant Availability that was held at the Ramada Inn in Rockville, Maryland on May 5--7, 1993. The Meeting was presented in cooperation with the Electric Power Research Institute, Oak Ridge National Laboratory and the International Atomic Energy Agency. There were approximately 65 participants from 13 countries at the Meeting. Individual reports have been cataloged separately.

19 CFR 206.4 - Notification of other agencies.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 19 Customs Duties 3 2014-04-01 2014-04-01 false Notification of other agencies. 206.4 Section 206.4 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW...

19 CFR 206.4 - Notification of other agencies.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 19 Customs Duties 3 2013-04-01 2013-04-01 false Notification of other agencies. 206.4 Section 206.4 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION NONADJUDICATIVE INVESTIGATIONS INVESTIGATIONS RELATING TO GLOBAL AND BILATERAL SAFEGUARD ACTIONS, MARKET DISRUPTION, TRADE DIVERSION, AND REVIEW...

15 CFR 1170.5 - Recommendations for agency organization.

Code of Federal Regulations, 2013 CFR

2013-01-01

... to use of the metric system. (b) Designate a senior policy official to be responsible for agency... the metric system. (e) Provide for internal guidelines, training and documentation to assure employee... Trade (Continued) TECHNOLOGY ADMINISTRATION, DEPARTMENT OF COMMERCE METRIC CONVERSION POLICY FOR FEDERAL...

15 CFR 1170.5 - Recommendations for agency organization.

Code of Federal Regulations, 2012 CFR

2012-01-01

... to use of the metric system. (b) Designate a senior policy official to be responsible for agency... the metric system. (e) Provide for internal guidelines, training and documentation to assure employee... Trade (Continued) TECHNOLOGY ADMINISTRATION, DEPARTMENT OF COMMERCE METRIC CONVERSION POLICY FOR FEDERAL...

Report on the 2013 US Environmental Protection Agency ...

EPA Pesticide Factsheets

Report This report summarizes presentations and discussions from the “2013 U.S Environmental Protection Agency (EPA) International Decontamination Research and Development Conference,” held November 5–7, 2013 at the U.S. EPA facilities in Research Triangle Park, North Carolina.

International Directory of Mental Retardation Resources.

ERIC Educational Resources Information Center

Dybwad, Rosemary F., Ed.

The directory lists and describes governmental and voluntary agencies, research, and other resources in the field of mental retardation in foreign countries. The first section, on international organizations, gives names, addresses, names of directors, and one or more paragraphs of description for the United Nations and its specialized agencies,…

Chemical Risk Assessment: Selected Federal Agencies’ Procedures, Assumptions, and Policies

DTIC Science & Technology

2001-08-01

adverse effects of exposures to hazardous substances or situations. It is a complex but valuable set of tools for federal regulatory agencies, helping...Act DES diethylstilbestrol DOT Department of Transportation ED effective dose EPA Environmental Protection Agency EPCRA Emergency Planning and...ISO International Organization for Standardization LED lowest effective dose LOAEL lowest observed adverse effect level LOEL lowest observed effect

Survey of EPA and Other Federal Agency Scientific Data Management Policies and Guidance, 2009

EPA Science Inventory

The purpose of this study is to compile and assess internal Environmental Protection Agency (EPA) scientific data management (SDM) policies and guidance. Additionally, this study examines SDM policies and guidance from other Federal Agencies engaged in science and technology, an...

77 FR 2713 - Agency Information Collection Extension

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-19

...) Package Title: U.S. Declaration under the Protocol Additional to the U.S.-IAEA Safeguards Agreement... Declaration to the International Atomic Energy Agency (IAEA) under Articles 2 and 3 of the Protocol Additional... performing activities at DOE Locations that would be declarable to the IAEA under the U.S. AP are affected by...

An empirical typology of private child and family serving agencies

PubMed Central

Collins-Camargo, Crystal; McBeath, Bowen; Wells, Rebecca; Bunger, Alicia

2014-01-01

Differences in how services are organized and delivered can contribute significantly to variation in outcomes experienced by children and families. However, few comparative studies identify the strengths and limitations of alternative delivery system configurations. The current study provides the first empirical typology of private agencies involved with the formal child welfare system. Data collected in 2011 from a national sample of private agencies were used to classify agencies into five distinct groups based on internal management capacity, service diversification, integration, and policy advocacy. Findings reveal considerable heterogeneity in the population of private child and family serving agencies. Cross-group comparisons suggest that differences in agencies’ strategic and structural characteristics correlated with agency directors’ perceptions of different pressures in their external environment. Future research can use this typology to better understand local service systems and the extent to which different agency strategies affect performance and other outcomes. Such information has implications for public agency contracting decisions and could inform system-level assessment and planning of services for children and families. PMID:24648603

22 CFR 1509.645 - Federal agency or agency.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Federal agency or agency. 1509.645 Section 1509.645 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1509.645 Federal agency or agency. Federal agency or agency...

20 CFR 439.645 - Federal agency or agency.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Federal agency or agency. 439.645 Section 439.645 Employees' Benefits SOCIAL SECURITY ADMINISTRATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 439.645 Federal agency or agency. Federal agency or agency...

International fieldwork placements in low-income countries: Exploring community perspectives.

PubMed

Shields, Megan; Quilty, Jenny; Dharamsi, Shafik; Drynan, Donna

2016-10-01

There has been a significant increase in the number of occupational and physical therapy students going on international fieldwork placements in low-income countries. Yet, there has been a lack of research describing this experience from the agencies that host students. The research question was 'how do members of an agency within a low-income country perceive, interpret and give meaning to international fieldwork placements where students from a Canadian university provide occupational and physical therapy services?' Purposive sampling was used to recruit participants from five affiliated international fieldwork sites. Six semi-structured interviews exploring the perspectives of individuals from agency sites in low-income countries facilitated the data collection. Interviews were audiotaped and transcribed verbatim for thematic analysis. Four themes provided insight into the participants' experience of hosting student therapists. Participants emphasised: (i) there was a reciprocity of learning between agency members and students; (ii) they felt responsible for the health and safety of the students, as well as providing an enriching experience; (iii) participants questioned the preparation phase; and (iv) recommendations were made by participants to strengthen partnerships while contemplating sustainable practices. This study highlighted that effective preparation, enhanced communication, reflection and reciprocity is necessary to achieve what hosting agencies view as sustainable international placements. These results provide a platform for stakeholders to question their current processes for fieldwork placement engagement and potential suggestions for improving current international fieldwork partnerships. © 2016 Occupational Therapy Australia.

28 CFR 83.645 - Federal agency or agency.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Federal agency or agency. 83.645 Section 83.645 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) GOVERNMENT-WIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (GRANTS) Definitions § 83.645 Federal agency or agency. Federal agency or agency...

34 CFR 84.645 - Federal agency or agency.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 1 2010-07-01 2010-07-01 false Federal agency or agency. 84.645 Section 84.645 Education Office of the Secretary, Department of Education GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 84.645 Federal agency or agency. Federal agency or agency...

22 CFR 1008.645 - Federal agency or agency.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Federal agency or agency. 1008.645 Section 1008.645 Foreign Relations INTER-AMERICAN FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1008.645 Federal agency or agency. Federal agency or agency means any...

45 CFR 1155.645 - Federal agency or agency.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false Federal agency or agency. 1155.645 Section 1155.645 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL FOUNDATION ON THE ARTS... (FINANCIAL ASSISTANCE) Definitions § 1155.645 Federal agency or agency. Federal agency or agency means any...

22 CFR 312.645 - Federal agency or agency.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Federal agency or agency. 312.645 Section 312.645 Foreign Relations PEACE CORPS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 312.645 Federal agency or agency. Federal agency or agency means any United States...

21 CFR 1405.645 - Federal agency or agency.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Federal agency or agency. 1405.645 Section 1405.645 Food and Drugs OFFICE OF NATIONAL DRUG CONTROL POLICY GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 1405.645 Federal agency or agency. Federal agency or agency...

40 CFR 262.58 - International agreements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 27 2013-07-01 2013-07-01 false International agreements. 262.58 Section 262.58 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... International agreements. (a) Any person who exports or imports wastes that are considered hazardous under U.S...

40 CFR 262.58 - International agreements.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 27 2012-07-01 2012-07-01 false International agreements. 262.58 Section 262.58 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... International agreements. (a) Any person who exports or imports wastes that are considered hazardous under U.S...

78 FR 31578 - Agency Information Collection Activities; Proposed Collection; Comments Requested: International...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-24

... Collection Activities; Proposed Collection; Comments Requested: International Terrorism Victim Compensation... Form/Collection: International Terrorism Victim Expense Reimbursement Program (ITVERP) Application. (3... of acts of international terrorism that occur outside the United States. Applicants seeking...

Teachers Negotiating Professional Agency through Literature-Based Assessment

ERIC Educational Resources Information Center

Simpson, Alyson

2017-01-01

Research reports teachers around the world currently face major challenges to their professional agency. They face numerous pressures from accountability measures operating in the highly politicised field of literacy education and standardised testing. At the same time international research encourages teachers to design rich assessment tasks…

Six years after the NRC review of EPA's Draft IRIS Toxicological Review of Formaldehyde: Regulatory implications of new science in evaluating formaldehyde leukemogenicity.

PubMed

Mundt, Kenneth A; Gentry, P Robinan; Dell, Linda D; Rodricks, Joseph V; Boffetta, Paolo

2018-02-01

Shortly after the International Agency for Research on Cancer (IARC) determined that formaldehyde causes leukemia, the United States Environmental Protection Agency (EPA) released its Draft IRIS Toxicological Review of Formaldehyde ("Draft IRIS Assessment"), also concluding that formaldehyde causes leukemia. Peer review of the Draft IRIS Assessment by a National Academy of Science committee noted that "causal determinations are not supported by the narrative provided in the draft" (NRC 2011). They offered recommendations for improving the Draft IRIS assessment and identified several important research gaps. Over the six years since the NRC peer review, significant new science has been published. We identify and summarize key recommendations made by NRC and map them to this new science, including extended analysis of epidemiological studies, updates of earlier occupational cohort studies, toxicological experiments using a sensitive mouse strain, mechanistic studies examining the role of exogenous versus endogenous formaldehyde in bone marrow, and several critical reviews. With few exceptions, new findings are consistently negative, and integration of all available evidence challenges the earlier conclusions that formaldehyde causes leukemia. Given formaldehyde's commercial importance, environmental ubiquity and endogenous production, accurate hazard classification and risk evaluation of whether exposure to formaldehyde from occupational, residential and consumer products causes leukemia are critical. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Challenges and future direction of molecular research in air pollution-related lung cancers.

PubMed

Shahadin, Maizatul Syafinaz; Ab Mutalib, Nurul Syakima; Latif, Mohd Talib; Greene, Catherine M; Hassan, Tidi

2018-04-01

Hazardous air pollutants or chemical release into the environment by a variety of natural and/or anthropogenic activities may give adverse effects to human health. Air pollutants such as sulphur dioxide (SO2), nitrogen oxides (NOx), carbon monoxide (CO), heavy metals and particulate matter (PM) affect number of different human organs, especially the respiratory system. The International Agency for Research on Cancer (IARC) reported that ambient air pollution is a cause of lung cancer. Recently, the agency has classified outdoor air pollution as well as PM air pollution as Group 1 carcinogens. In addition, several epidemiological studies have shown a positive association between air pollutants to lung cancer risks and mortality. However, there are only a few studies examining the molecular effects of air pollution exposure specifically in lung cancer due to multiple challenges to mimic air pollution exposure in basic experimentation. Another major issue is the lack of adequate adjustments for exposure misclassification as air pollution may differ temporo-spatially and socioeconomically. Thus, the purpose of this paper is to review the current molecular understanding of air pollution-related lung cancer and potential future direction in this challenging yet important research field. Copyright © 2018 Elsevier B.V. All rights reserved.

Physics and Its Multiple Roles in the International Atomic Energy Agency

NASA Astrophysics Data System (ADS)

Massey, Charles D.

2017-01-01

The IAEA is the world's centre for cooperation in the nuclear field. It was set up as the world's ``Atoms for Peace'' organization in 1957 within the United Nations family. The Agency works with its Member States and multiple partners worldwide to promote the safe, secure and peaceful use of nuclear technologies. Three main areas of work underpin the IAEA's mission: Safety and Security, Science and Technology, and Safeguards and Verification. To carry out its mission, the Agency is authorized to encourage and assist research on, and development and practical application of, atomic energy for peaceful uses throughout the world; foster the exchange of scientific and technical information on peaceful uses of atomic energy; and encourage the exchange of training of scientists and experts in the field of peaceful uses of atomic energy. Nowadays, nuclear physics and nuclear technology are applied in a great variety of social areas, such as power production, medical diagnosis and therapies, environmental protection, security control, material tests, food processing, waste treatments, agriculture and artifacts analysis. This presentation will cover the role and practical application of physics at the IAEA, and, in particular, focus on the role physics has, and will play, in nuclear security.

KENNEDY SPACE CENTER, FLA. - At a ceremony highlighting the arrival of two major components of the International Space Station, Node 2 and the Japanese Experiment Module (JEM), ownership of Node 2 was officially transferred between the European Space Agency (ESA) and NASA. Shaking hands after the signing are Alan Thirkettle (center), International Space Station Program manager for Node 2, ESA; and NASA’s Michael C. Kostelnik (right), deputy associate administrator for International Space Station and Shuttle Programs. At left, also part of the signing, is Andrea Lorenzoni (left), International Space Station Program manager for Node 2, Italian Space Agency. NASA's Node 2, built by ESA in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s William Gerstenmaier, International Space Station Program manager; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - At a ceremony highlighting the arrival of two major components of the International Space Station, Node 2 and the Japanese Experiment Module (JEM), ownership of Node 2 was officially transferred between the European Space Agency (ESA) and NASA. Shaking hands after the signing are Alan Thirkettle (center), International Space Station Program manager for Node 2, ESA; and NASA’s Michael C. Kostelnik (right), deputy associate administrator for International Space Station and Shuttle Programs. At left, also part of the signing, is Andrea Lorenzoni (left), International Space Station Program manager for Node 2, Italian Space Agency. NASA's Node 2, built by ESA in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s William Gerstenmaier, International Space Station Program manager; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

KENNEDY SPACE CENTER, FLA. - Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency, speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (far left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, and William Gerstenmaier, International Space Station Program manager ; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency, speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (far left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, and William Gerstenmaier, International Space Station Program manager ; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

KENNEDY SPACE CENTER, FLA. - NASA's Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, speaks to guests and the media gathered in the Space Station Processing Facility for a ceremony to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (far left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr. (second from left); William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - NASA's Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, speaks to guests and the media gathered in the Space Station Processing Facility for a ceremony to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (far left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr. (second from left); William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

KENNEDY SPACE CENTER, FLA. - Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan, speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module (above right) of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (far left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr. (second from left); NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs and William Gerstenmaier, International Space Station Program manager ; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; and Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan, speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module (above right) of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (far left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr. (second from left); NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs and William Gerstenmaier, International Space Station Program manager ; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; and Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency.

KENNEDY SPACE CENTER, FLA. - In the Space Station Processing Facility, media and guests listen intently to remarks during a ceremony to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony included these speakers: KSC Director Roy Bridges Jr.; NASA's Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - In the Space Station Processing Facility, media and guests listen intently to remarks during a ceremony to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony included these speakers: KSC Director Roy Bridges Jr.; NASA's Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

KENNEDY SPACE CENTER, FLA. - Center Director Roy Bridges Jr. speaks to the media and guests gathered in the Space Station Processing Facility for a ceremony to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (left) , deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: NASA's Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - Center Director Roy Bridges Jr. speaks to the media and guests gathered in the Space Station Processing Facility for a ceremony to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (left) , deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: NASA's Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

KENNEDY SPACE CENTER, FLA. - Center Director Roy Bridges Jr. speaks to the media and guests gathered in the Space Station Processing Facility for a ceremony to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: NASA's Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - Center Director Roy Bridges Jr. speaks to the media and guests gathered in the Space Station Processing Facility for a ceremony to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: NASA's Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

KENNEDY SPACE CENTER, FLA. - Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan, speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs and William Gerstenmaier, International Space Station Program manager ; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; and Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan, speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs and William Gerstenmaier, International Space Station Program manager ; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; and Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency.

KENNEDY SPACE CENTER, FLA. - At a ceremony highlighting the arrival of two major components of the International Space Station, William Gerstenmaier, International Space Station Program manager, points to one of the components as he speaks to guests and the media gathered in the Space Station Processing Facility. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - At a ceremony highlighting the arrival of two major components of the International Space Station, William Gerstenmaier, International Space Station Program manager, points to one of the components as he speaks to guests and the media gathered in the Space Station Processing Facility. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

KENNEDY SPACE CENTER, FLA. - Center Director Roy Bridges Jr. speaks to the media and guests gathered in the Space Station Processing Facility for a ceremony to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (far left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: NASA's Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - Center Director Roy Bridges Jr. speaks to the media and guests gathered in the Space Station Processing Facility for a ceremony to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (far left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: NASA's Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

KENNEDY SPACE CENTER, FLA. - Alan Thirkettle, International Space Station Program manager for Node 2, European Space Agency (ESA), speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by ESA in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs and William Gerstenmaier, International Space Station Program manager; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - Alan Thirkettle, International Space Station Program manager for Node 2, European Space Agency (ESA), speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by ESA in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs and William Gerstenmaier, International Space Station Program manager; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

KENNEDY SPACE CENTER, FLA. - NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, speaks to guests and the media gathered in the Space Station Processing Facility for a ceremony to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs, speaks to guests and the media gathered in the Space Station Processing Facility for a ceremony to highlight the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope) arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

KENNEDY SPACE CENTER, FLA. - Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency, speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency, speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

KENNEDY SPACE CENTER, FLA. - Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan, speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (far left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr. (second from left); NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; and Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan, speaks to guests and the media gathered in the Space Station Processing Facility at a ceremony highlighting the arrival of two major components of the International Space Station. NASA's Node 2, built by the European Space Agency (ESA) in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. The ceremony held today included the official transfer of ownership signing of Node 2 between the ESA and NASA.. Emceed by Lisa Malone (far left), deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr. (second from left); NASA’s Michael C. Kostelnik, deputy associate administrator for International Space Station and Shuttle Programs and William Gerstenmaier, International Space Station Program manager; Alan Thirkettle, International Space Station Program manager for Node 2, ESA; and Andrea Lorenzoni, International Space Station Program manager for Node 2, Italian Space Agency.

A review of the International Atomic Energy Agency (IAEA) international standards for tissue banks.

PubMed

Morales Pedraza, Jorge; Lobo Gajiwala, Astrid; Martinez Pardo, María Esther

2012-03-01

The IAEA International Standards for Tissue Banks published in 2003 were based on the Standards then currently in use in the USA and the European Union, among others, and reflect the best practices associated with the operation of a tissue bank. They cover legal, ethical and regulatory controls as well as requirements and procedures from donor selection and tissue retrieval to processing and distribution of finished tissue for clinical use. The application of these standards allows tissue banks to operate with the current good tissue practice, thereby providing grafts of high quality that satisfy the national and international demand for safe and biologically useful grafts. The objective of this article is to review the IAEA Standards and recommend new topics that could improve the current version.

Illinois Accelerator Research Center

DOE PAGES

Kroc, Thomas K.; Cooper, Charlie A.

2017-10-26

The Illinois Accelerator Research Center (IARC) hosts a new accelerator development program at Fermi National Accelerator Laboratory. IARC provides access to Fermi's state-of-the-art facilities and technologies for research, development and industrialization of particle accelerator technology. In addition to facilitating access to available existing Fermi infrastructure, the IARC Campus has a dedicated 36,000 ft2 heavy assembly building (HAB) with all the infrastructure needed to develop, commission and operate new accelerators. Connected to the HAB is a 47,000 ft Office, Technology and Engineering (OTE) building, paid for by the state, that has office, meeting, and light technical space. The OTE building, whichmore » contains the Accelerator Physics Center, and nearby Accelerator and Technical divisions provide IARC collaborators with unique access to world class expertise in a wide array of accelerator technologies. Finally, at IARC scientists and engineers from Fermilab and academia work side by side with industrial partners to develop breakthroughs in accelerator science and translate them into applications for the nation's health, wealth and security.« less

Illinois Accelerator Research Center

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kroc, Thomas K.; Cooper, Charlie A.

The Illinois Accelerator Research Center (IARC) hosts a new accelerator development program at Fermi National Accelerator Laboratory. IARC provides access to Fermi's state-of-the-art facilities and technologies for research, development and industrialization of particle accelerator technology. In addition to facilitating access to available existing Fermi infrastructure, the IARC Campus has a dedicated 36,000 ft2 heavy assembly building (HAB) with all the infrastructure needed to develop, commission and operate new accelerators. Connected to the HAB is a 47,000 ft Office, Technology and Engineering (OTE) building, paid for by the state, that has office, meeting, and light technical space. The OTE building, whichmore » contains the Accelerator Physics Center, and nearby Accelerator and Technical divisions provide IARC collaborators with unique access to world class expertise in a wide array of accelerator technologies. Finally, at IARC scientists and engineers from Fermilab and academia work side by side with industrial partners to develop breakthroughs in accelerator science and translate them into applications for the nation's health, wealth and security.« less

Illinois Accelerator Research Center

NASA Astrophysics Data System (ADS)

Kroc, Thomas K.; Cooper, Charlie A.

The Illinois Accelerator Research Center (IARC) hosts a new accelerator development program at Fermi National Accelerator Laboratory. IARC provides access to Fermi's state-of-the-art facilities and technologies for research, development and industrialization of particle accelerator technology. In addition to facilitating access to available existing Fermi infrastructure, the IARC Campus has a dedicated 36,000 ft2 Heavy Assembly Building (HAB) with all the infrastructure needed to develop, commission and operate new accelerators. Connected to the HAB is a 47,000 ft2 Office, Technology and Engineering (OTE) building, paid for by the state, that has office, meeting, and light technical space. The OTE building, which contains the Accelerator Physics Center, and nearby Accelerator and Technical divisions provide IARC collaborators with unique access to world class expertise in a wide array of accelerator technologies. At IARC scientists and engineers from Fermilab and academia work side by side with industrial partners to develop breakthroughs in accelerator science and translate them into applications for the nation's health, wealth and security.

International Coordination of Exploring and Using Lunar Polar Volatiles

NASA Technical Reports Server (NTRS)

Gruener, J. E.; Suzuki, N. H.; Carpenter, J. D.

2016-01-01

Fourteen international space agencies are participating in the International Space Exploration Coordination Group (ISECG), working together to advance a long-range strategy for human and robotic space exploration beyond low earth orbit. The ISECG is a voluntary, non-binding international coordination mechanism through which individual agencies may exchange information regarding interests, objectives, and plans in space exploration with the goal of strengthening both individual exploration programs as well as the collective effort. The ISECG has developed a Global Exploration Roadmap (GER) that reflects the coordinated international dialog and continued preparation for exploration beyond low-Earth orbit, beginning with the Moon and cis-lunar space, and continuing to near-Earth asteroids, and Mars.

Feedback about action performed can alter the sense of self-agency

PubMed Central

Kumar, Neeraj; Manjaly, Jaison A.; Miyapuram, Krishna P.

2014-01-01

Sense of agency refers to the sense of authorship of an action and its outcome. Sense of agency is often explained through computational models of motor control (e.g., the comparator model). Previous studies using the comparator model have manipulated action-outcome contingency to understand its effect on the sense of agency. More recent studies have shown that cues related to outcome, priming outcome and priming action have an effect on agency attribution. However, relatively few studies have focused on the effect of recalibrating internal predictions on the sense of agency. This study aims to investigate how feedback about action can recalibrate prediction and modulates the sense of agency. While participants performed a Flanker task, we manipulated the feedback about the validity of the action performed, independent of their responses. When true feedback is given, the sense of agency would reflect congruency between the sensory outcome and the action performed. The results show an opposite effect on the sense of agency when false feedback was given. We propose that feedback about action performed can recalibrate the prediction of sensory outcome and thus alter the sense of agency. PMID:24611059

Internal Control Weaknesses Contributed to the Mismanagement and Misuse of Federal Funds at Selected Community Action Agencies.

DTIC Science & Technology

1981-07-10

reimbursement of expenses. --Inadequate control over fixed assets. Excess cash GAO reviewed several community action agencies and found that millions...buildings. (See pp. 10-13.) Duplicate reimbursement of expenses Some community action agencies and their dele- gates GAO reviewed have charged nearly...1 million of expenses to more than one Federal grant. For example, one agency received nearly $855,000 in dual reimbursements between July 1974 and

76 FR 19909 - International Terrorism Victim Expense Reimbursement Program

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-11

... 1121-AA78 International Terrorism Victim Expense Reimbursement Program AGENCY: Office of Justice... promulgating this interim-final rule for its International Terrorism Victim Expense Reimbursement Program... international terrorism. DATES: Effective date: This interim-final rule is effective April 11, 2011. Comment...

KENNEDY SPACE CENTER, FLA. - Alan Thirkettle (center), International Space Station Program manager for Node 2, European Space Agency (ESA); and NASA’s Michael C. Kostelnik (right), deputy associate administrator for International Space Station and Shuttle Programs, sign documents officially transferring ownership of Node 2 between the ESA and NASA. At left, also part of the signing, is Andrea Lorenzoni (left), International Space Station Program manager for Node 2, Italian Space Agency. NASA's Node 2, built by ESA in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s William Gerstenmaier, International Space Station Program manager; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

NASA Image and Video Library

2003-06-18

KENNEDY SPACE CENTER, FLA. - Alan Thirkettle (center), International Space Station Program manager for Node 2, European Space Agency (ESA); and NASA’s Michael C. Kostelnik (right), deputy associate administrator for International Space Station and Shuttle Programs, sign documents officially transferring ownership of Node 2 between the ESA and NASA. At left, also part of the signing, is Andrea Lorenzoni (left), International Space Station Program manager for Node 2, Italian Space Agency. NASA's Node 2, built by ESA in Italy, arrived at KSC on June 1. It will be the next pressurized module installed on the Station. The pressurized module of the Japanese Experiment Module (JEM), named "Kibo" (Hope), arrived at KSC on June 4. It is Japan's primary contribution to the Station. Emceed by Lisa Malone, deputy director of External Relations and Business Development at KSC, the ceremony also included these speakers: Center Director Roy Bridges Jr.; NASA’s William Gerstenmaier, International Space Station Program manager; and Kuniaki Shiraki, JEM Project manager, National Aerospace and Development Agency of Japan.

75 FR 47520 - Standards of Performance for Stationary Compression Ignition and Spark Ignition Internal...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-06

... Ignition Internal Combustion Engines AGENCY: Environmental Protection Agency (EPA). ACTION: Extension of... for stationary compression ignition and spark ignition internal combustion engines. In this [[Page... combustion engines. After publication of the proposed rule, EPA received requests from the American Petroleum...

Mexican Space Agency and NASA Agreement

NASA Image and Video Library

2013-03-18

Leland Melvin (right), NASA Associate Administrator for Education, along with the head of the Mexican Space Agency, Dr. Francisco Javier Mendieta Jimenez shake hands after signing a Reimbursable Space Act Agreement (RSAA) for a NASA International Internship Program as NASA Administrator Charles Bolden looks on, Monday, March 18, 2013 at NASA Headquarters in Washington. The International Internship Program is a pilot program developed at NASA which will provide and avenue for non-US students to come to NASA for an internship. US students will be paired with a foreign student to work on a NASA research project under the guidance of a mentor. This is the first NASA-Mexico agreement signed. Photo Credit: (NASA/Carla Cioffi)

Mexican Space Agency and NASA Agreement

NASA Image and Video Library

2013-03-18

Leland Melvin (right), NASA Associate Administrator for Education, along with the head of the Mexican Space Agency, Dr. Francisco Javier Mendieta Jimenez pose for a photo after signing a Reimbursable Space Act Agreement (RSAA) for a NASA International Internship Program as NASA Administrator Charles Bolden looks on, Monday, March 18, 2013 at NASA Headquarters in Washington. The International Internship Program is a pilot program developed at NASA which will provide and avenue for non-US students to come to NASA for an internship. US students will be paired with a foreign student to work on a NASA research project under the guidance of a mentor. This is the first NASA-Mexico agreement signed. Photo Credit: (NASA/Carla Cioffi)

76 FR 65639 - International Mail: Proposed Product Rate and Fee Changes

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-24

... Customs Clearance and Delivery Fee International Reply Coupons International Business Reply Service The... * * * * * International Business Reply Service (382) [For each country that offers International Business Reply Service... POSTAL SERVICE 39 CFR Part 20 International Mail: Proposed Product Rate and Fee Changes AGENCY...

[New global challenges: the role of international organizations].

PubMed

Nardi, L; Scaroni, E; Riccardo, F; De Rosa, A G; Pacini, A; Russo, G; Pacifici, L E

2007-01-01

Facing the numerous humanitarian emergencies that upset the international balances, the International Organisations (IO) who intervene are: the Agencies of the United Nations (UN), the International Federation of the Red Cross (IFRC) and NGOs. In the sector of international health cooperation, the World Health Organization (WHO) has elaborated a document, the International Health Regulations (IHR), that regulates the health workers' activity during a health emergency. In this paper different International Organizations employed in international humanitarian crisis are described.

77 FR 58707 - Minimum Internal Control Standards

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-21

... Gaming Commission 25 CFR Part 543 Minimum Internal Control Standards; Final Rule #0;#0;Federal Register... Control Standards AGENCY: National Indian Gaming Commission, Interior. ACTION: Final rule. SUMMARY: The National Indian Gaming Commission (NIGC) amends its minimum internal control standards for Class II gaming...

78 FR 54245 - Agency Information Collection Activities; Submission to the Office of Management and Budget for...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-03

... DEPARTMENT OF EDUCATION [Docket No.: ED-2013-ICCD-0087] Agency Information Collection Activities... International Mathematics and Science Study (TIMSS): 2015 Recruitment and Field Test AGENCY: Institute of Education Sciences/National Center for Education Statistics (IES), Department of Education (ED). ACTION...

75 FR 34017 - International Mail Manual; Incorporation by Reference

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-16

... POSTAL SERVICE 39 CFR Part 20 International Mail Manual; Incorporation by Reference AGENCY: Postal... Mailing Standards of the United States Postal Service, International Mail Manual (IMM[supreg]) and its..., (202) 268-3789. SUPPLEMENTARY INFORMATION: Issue 36 of the International Mail Manual was issued on May...

22 CFR 1101.13 - Agency review of request to correct or amend a record.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Agency review of request to correct or amend a record. 1101.13 Section 1101.13 Foreign Relations INTERNATIONAL BOUNDARY AND WATER COMMISSION, UNITED STATES AND MEXICO, UNITED STATES SECTION PRIVACY ACT OF 1974 § 1101.13 Agency review of request to...

Quality Assurance of Quality Assurance Agencies from an Asian Perspective: Regulation, Autonomy and Accountability

ERIC Educational Resources Information Center

Hou, Angela Yung-Chi; Ince, Martin; Tsai, Sandy; Chiang, Chung Lin

2015-01-01

As quality guardians of higher education, quality assurance agencies are required to guarantee the credibility of the review process and to ensure the objectivity and transparency of their decisions and recommendations. These agencies are therefore expected to use a range of internal and external approaches to prove the quality of their review…

22 CFR 1101.13 - Agency review of request to correct or amend a record.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Agency review of request to correct or amend a record. 1101.13 Section 1101.13 Foreign Relations INTERNATIONAL BOUNDARY AND WATER COMMISSION, UNITED STATES AND MEXICO, UNITED STATES SECTION PRIVACY ACT OF 1974 § 1101.13 Agency review of request to...

22 CFR 1101.13 - Agency review of request to correct or amend a record.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Agency review of request to correct or amend a record. 1101.13 Section 1101.13 Foreign Relations INTERNATIONAL BOUNDARY AND WATER COMMISSION, UNITED STATES AND MEXICO, UNITED STATES SECTION PRIVACY ACT OF 1974 § 1101.13 Agency review of request to...

Using the Hill viewpoints from 1965 for evaluating strengths of evidence of the risk for brain tumors associated with use of mobile and cordless phones.

PubMed

Hardell, Lennart; Carlberg, Michael

2013-01-01

Wireless phones, i.e., mobile phones and cordless phones, emit radiofrequency electromagnetic fields (RF-EMF) when used. An increased risk of brain tumors is a major concern. The International Agency for Research on Cancer (IARC) at the World Health Organization (WHO) evaluated the carcinogenic effect to humans from RF-EMF in May 2011. It was concluded that RF-EMF is a group 2B, i.e., a "possible", human carcinogen. Bradford Hill gave a presidential address at the British Royal Society of Medicine in 1965 on the association or causation that provides a helpful framework for evaluation of the brain tumor risk from RF-EMF. All nine issues on causation according to Hill were evaluated. Regarding wireless phones, only studies with long-term use were included. In addition, laboratory studies and data on the incidence of brain tumors were considered. The criteria on strength, consistency, specificity, temporality, and biologic gradient for evidence of increased risk for glioma and acoustic neuroma were fulfilled. Additional evidence came from plausibility and analogy based on laboratory studies. Regarding coherence, several studies show increasing incidence of brain tumors, especially in the most exposed area. Support for the experiment came from antioxidants that can alleviate the generation of reactive oxygen species involved in biologic effects, although a direct mechanism for brain tumor carcinogenesis has not been shown. In addition, the finding of no increased risk for brain tumors in subjects using the mobile phone only in a car with an external antenna is supportive evidence. Hill did not consider all the needed nine viewpoints to be essential requirements. Based on the Hill criteria, glioma and acoustic neuroma should be considered to be caused by RF-EMF emissions from wireless phones and regarded as carcinogenic to humans, classifying it as group 1 according to the IARC classification. Current guidelines for exposure need to be urgently revised.

Is Helicobacter pylori really the cause of gastric cancer?

PubMed

Nyrén, O

1998-08-01

Since 1994, when the International Agency for Research on Cancer (IARC) designated Helicobacter pylori a human carcinogen, a considerable number of new studies have examined the association of this microorganism with risk of gastric cancer. The aim of this review was to critically evaluate current evidence of a causal relationship between the infection and gastric cancer in humans, taking these new studies into account. A MEDLINE search for the years 1982 through March 1998 yielded eight cohort studies, 40 case-control studies and eight ecologic studies. They were divided into four categories according to the weight of the evidence produced. In the category producing the strongest evidence, the cohort studies, five out of eight studies (including the three that formed the basis for the IARC decision) found a statistically significant excess risk of gastric cancer among the infected with odds ratios ranging between 2.8 and 6.0. Two cohort studies showed a non-significant tendency towards a positive association, but with point estimates indicating no more than a 50-60% excess risk among the H. pylori seropositive, and one apparently well-performed cohort study was completely negative. The two population-based case-control studies published to date found statistically non-significant odds ratios no higher than 1.3 and 1.4. Thus, the evidence of a strong causal link between H. pylori infection and gastric cancer has, if anything, become less convincing. Recent studies seem to indicate that the strength of the association may vary with type of H. pylori strain, and possibly presence of effect-modifying co-factors in the host and/or the environment. Future studies need to identify high-risk constellations of carcinogenic strains and unfavorable co-factors to make targeted prophylaxis cost-effective.

Glyphosate rodent carcinogenicity bioassay expert panel review.

PubMed

Williams, Gary M; Berry, Colin; Burns, Michele; de Camargo, Joao Lauro Viana; Greim, Helmut

2016-09-01

Glyphosate has been rigorously and extensively tested for carcinogenicity by administration to mice (five studies) and to rats (nine studies). Most authorities have concluded that the evidence does not indicate a cancer risk to humans. The International Agency for Research on Cancer (IARC), however, evaluated some of the available data and concluded that glyphosate probably is carcinogenic to humans. The expert panel convened by Intertek assessed the findings used by IARC, as well as the full body of evidence and found the following: (1) the renal neoplastic effects in males of one mouse study are not associated with glyphosate exposure, because they lack statistical significance, strength, consistency, specificity, lack a dose-response pattern, plausibility, and coherence; (2) the strength of association of liver hemangiosarcomas in a different mouse study is absent, lacking consistency, and a dose-response effect and having in high dose males only a significant incidence increase which is within the historical control range; (3) pancreatic islet-cell adenomas (non-significant incidence increase), in two studies of male SD rats did not progress to carcinomas and lacked a dose-response pattern (the highest incidence is in the low dose followed by the high dose); (4) in one of two studies, a non-significant positive trend in the incidence of hepatocellular adenomas in male rats did not lead to progression to carcinomas; (5) in one of two studies, the non-significant positive trend in the incidence of thyroid C-cell adenomas in female rats was not present and there was no progression of adenomas to carcinomas at the end of the study. Application of criteria for causality considerations to the above mentioned tumor types and given the overall weight-of-evidence (WoE), the expert panel concluded that glyphosate is not a carcinogen in laboratory animals.

13 CFR 147.645 - Federal agency or agency.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Federal agency or agency. 147.645 Section 147.645 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (NONPROCUREMENT) Definitions § 147.645 Federal agency or agency. Federal...

Training the Future - Interns Harvesting & Testing Plant Experim

NASA Image and Video Library

2017-07-19

In the Space Life Sciences Laboratory at NASA's Kennedy Space Center in Florida, student interns are joining agency scientists, contributing in the area of plant growth research for food production in space. The agency attracts its future workforce through the NASA Internship, Fellowships and Scholarships, or NIFS, Program.

10 CFR 607.645 - Federal agency or agency.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Federal agency or agency. 607.645 Section 607.645 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 607.645 Federal agency or agency. Department of Energy means the U.S...

31 CFR 20.645 - Federal agency or agency.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Federal agency or agency. 20.645 Section 20.645 Money and Finance: Treasury Office of the Secretary of the Treasury GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 20.645 Federal agency or agency...

31 CFR 20.645 - Federal agency or agency.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance: Treasury 1 2013-07-01 2013-07-01 false Federal agency or agency. 20.645 Section 20.645 Money and Finance: Treasury Office of the Secretary of the Treasury GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 20.645 Federal agency or agency...

31 CFR 20.645 - Federal agency or agency.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance: Treasury 1 2012-07-01 2012-07-01 false Federal agency or agency. 20.645 Section 20.645 Money and Finance: Treasury Office of the Secretary of the Treasury GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 20.645 Federal agency or agency...

31 CFR 20.645 - Federal agency or agency.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance: Treasury 1 2014-07-01 2014-07-01 false Federal agency or agency. 20.645 Section 20.645 Money and Finance: Treasury Office of the Secretary of the Treasury GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 20.645 Federal agency or agency...

31 CFR 20.645 - Federal agency or agency.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance: Treasury 1 2011-07-01 2011-07-01 false Federal agency or agency. 20.645 Section 20.645 Money and Finance: Treasury Office of the Secretary of the Treasury GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 20.645 Federal agency or agency...

Mobile phone use and glioma risk: comparison of epidemiological study results with incidence trends in the United States.

PubMed

Little, M P; Rajaraman, P; Curtis, R E; Devesa, S S; Inskip, P D; Check, D P; Linet, M S

2012-03-08

In view of mobile phone exposure being classified as a possible human carcinogen by the International Agency for Research on Cancer (IARC), we determined the compatibility of two recent reports of glioma risk (forming the basis of the IARC's classification) with observed incidence trends in the United States. Comparison of observed rates with projected rates of glioma incidence for 1997-2008. We estimated projected rates by combining relative risks reported in the 2010 Interphone study and a 2011 Swedish study by Hardell and colleagues with rates adjusted for age, registry, and sex; data for mobile phone use; and various latency periods. US population based data for glioma incidence in 1992-2008, from 12 registries in the Surveillance, Epidemiology, and End Results (SEER) programme (Atlanta, Detroit, Los Angeles, San Francisco, San Jose-Monterey, Seattle, rural Georgia, Connecticut, Hawaii, Iowa, New Mexico, and Utah). Data for 24,813 non-Hispanic white people diagnosed with glioma at age 18 years or older. Age specific incidence rates of glioma remained generally constant in 1992-2008 (-0.02% change per year, 95% confidence interval -0.28% to 0.25%), a period coinciding with a substantial increase in mobile phone use from close to 0% to almost 100% of the US population. If phone use was associated with glioma risk, we expected glioma incidence rates to be higher than those observed, even with a latency period of 10 years and low relative risks (1.5). Based on relative risks of glioma by tumour latency and cumulative hours of phone use in the Swedish study, predicted rates should have been at least 40% higher than observed rates in 2008. However, predicted glioma rates based on the small proportion of highly exposed people in the Interphone study could be consistent with the observed data. Results remained valid if we used either non-regular users or low users of mobile phones as the baseline category, and if we constrained relative risks to be more than 1. Raised

76 FR 50414 - International Mail Manual; Incorporation by Reference

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-15

... POSTAL SERVICE 39 CFR Part 20 International Mail Manual; Incorporation by Reference AGENCY: Postal... Standards of the United States Postal Service, International Mail Manual (IMM[supreg]) dated April 17, 2011.... SUPPLEMENTARY INFORMATION: The International Mail Manual was issued on April 17, 2011, and was updated with...

77 FR 64724 - International Mail Manual; Incorporation by Reference

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-23

... POSTAL SERVICE 39 CFR Part 20 International Mail Manual; Incorporation by Reference AGENCY: Postal... Standards of the United States Postal Service, International Mail Manual (IMM[supreg]) dated June 24, 2012... International Mail Manual was issued on June 24, 2012, and was updated with postal bulletin revisions through...

Human papillomaviruses and skin cancer.

PubMed

Smola, Sigrun

2014-01-01

Human papillomaviruses (HPVs) infect squamous epithelia and can induce hyperproliferative lesions. More than 120 different HPV types have been characterized and classified into five different genera. While mucosal high-risk HPVs have a well-established causal role in anogenital carcinogenesis, the biology of cutaneous HPVs is less well understood. The clinical relevance of genus beta-PV infection has clearly been demonstrated in patients suffering from epidermodysplasia verruciformis (EV), a rare inherited disease associated with ahigh rate of skin cancer. In the normal population genus beta-PV are suspected to have an etiologic role in skin carcinogenesis as well but this is still controversially discussed. Their oncogenic potency has been investigated in mouse models and in vitro. In 2009, the International Agency for Research on Cancer (IARC) classified the genus beta HPV types 5 and 8 as "possible carcinogenic" biological agents (group 2B) in EV disease. This chapter will give an overview on the knowns and unknowns of infections with genus beta-PV and discuss their potential impact on skin carcinogenesis in the general population.

Arsenic and breast cancer: a systematic review of epidemiologic studies.

PubMed

Khanjani, Narges; Jafarnejad, Abu-Bakr; Tavakkoli, Leila

2017-09-26

Arsenic is one of the heavy metals known to be a cause of cancer and many other serious human health problems. The International Agency for Research on Cancer (IARC), has classified arsenic as a Group 1 carcinogen. Studies were performed in different populations to investigate the association between arsenic and breast cancer and the present paper attempts to review these studies. Accessible electronic resources including, PubMed, Web of Knowledge, Science Direct and Scopus and Google Scholar were searched, with relevant phrases up to October 30, 2016. All articles were reviewed by two people separately and among them, original epidemiologic studies that investigated the association between breast cancer and exposure to arsenic were included. Eventually seven articles were selected from 126 retrieved articles. Although three studies (one case-control and two ecological) were not able to show a significant affect, others provide some evidence of a relation between arsenic and breast cancer in specific subgroups. Exposure to arsenic may increase the risk of breast cancer. The strength of this relation can vary due to regional and individual differences.

Estimating occupational exposure to carcinogens in Quebec.

PubMed

Labrèche, France; Duguay, Patrice; Ostiguy, Claude; Boucher, Alexandre; Roberge, Brigitte; Peters, Cheryl E; Demers, Paul A

2013-09-01

We estimated the extent of exposure to occupational carcinogens in Quebec, Canada, to help raise awareness of occupational cancers. Proportions of workers exposed to 21 recognized and 17 probable carcinogens (according to Quebec occupational health regulation and the International Agency for Research on Cancer [IARC] classification) were extracted from various sources: workplace monitoring data, research projects, a population survey, radiation protection data, exposure estimates from the Carcinogen Exposure Canada (CAREX Canada) Project database, and published exposure data. These proportions were applied to Quebec labor force data. Among the 38 studied, carcinogens with the largest proportions of exposed workers were solar radiation (6.6% of workers), night shift work/rotating shift work including nights (6.0%), diesel exhaust fumes (4.4%), wood dust (2.9%) and polycyclic aromatic hydrocarbons (2.0%). More than 15 carcinogens were identified in several industrial sectors, and up to 100,000 young workers are employed in these sectors. Although crude, estimates obtained with different data sources allow identification of research and intervention priorities for cancer in Quebec. Copyright © 2013 Wiley Periodicals, Inc.

Beyond gastric adenocarcinoma: Multimodality assessment of common and uncommon gastric neoplasms

PubMed Central

Richman, Danielle M.; Tirumani, Sree Harsha; Hornick, Jason L.; Fuchs, Charles S.; Howard, Stephanie; Krajewski, Katherine; Ramaiya, Nikhil; Rosenthal, Michael

2016-01-01

Despite advances in molecular biology, imaging, and treatment, gastric neoplasms remain a significant cause of morbidity and mortality; gastric adenocarcinoma is the fifth most common malignancy and third most common cause of death worldwide (Brenner et al., Methods Mol Biol 472:467–477, 2009; Howson et al. Epidemiol Rev 8:1–27, 1986; Roder, Gastric Cancer 5(Suppl 1):5–11, 2002; Ferlay et al., GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC CancerBase No. 11 [Internet]. International Agency for Research on Cancer, 2013). Because of both the frequency at which malignant gastric tumors occur as well as the worldwide impact, gastric neoplasms remain important lesions to identify and characterize on all imaging modalities. Despite the varied histologies and behaviors of these neoplasms, many have similar imaging features. Nonetheless, the treatment, management, and prognosis of gastric neoplasms vary by pathology, so it is essential for the radiologist to make every effort to differentiate between these lesions and raise the less common entities as differential diagnostic considerations when appropriate. PMID:27645897

Appropriations for FY2002: VA, HUD, and Independent Agencies

DTIC Science & Technology

2001-09-20

on internal HUD management issues, and to wait for the recommendations of the Millennial Housing Commission (due early in 2002) before starting new...competitive basis and will be administered by state housing finance agencies, and are expected to assist over 130,000 first-time buyers each year. Funds will

Cultural Penetration in Latin America through Multinational Advertising Agencies.

ERIC Educational Resources Information Center

Del Toro, Wanda

Few studies have addressed the issue of cultural penetration of Latin American countries by multinational corporations (MNCs) and multinational advertising agencies (MAAs). Whether they are considered multinational or transnational, MAAs have expanded as a form of international communication in the global market, forming the backbone of MNCs.…

41 CFR 102-118.115 - Must my agency use a GBL?

Code of Federal Regulations, 2010 CFR

2010-07-01

... the maximum extent possible. Effective March 31, 2002, your agency must phase out the use of the... for international shipments. [65 FR 24569, Apr. 26, 2000, as amended at 66 FR 48812, Sept. 24, 2001] ...

Closing the Wage Gap. An International Perspective.

ERIC Educational Resources Information Center

National Committee on Pay Equity, Washington, DC.

This document comprises a report on international progress to close the "wage gap", the differential between the earnings of women and men. Information was gathered on pay equity activities from a survey of government agencies, trade unions, women's organizations, and international bodies. Almost all of the jurisdictions surveyed have…

Humans on the International Space Station-How Research, Operations, and International Collaboration are Leading to New Understanding of Human Physiology and Performance in Microgravity

NASA Technical Reports Server (NTRS)

Ronbinson, Julie A.; Harm, Deborah L.

2009-01-01

As the International Space Station (ISS) nears completion, and full international utilization is achieved, we are at a scientific crossroads. ISS is the premier location for research aimed at understanding the effects of microgravity on the human body. For applications to future human exploration, it is key for validation, quantification, and mitigation of a wide variety of spaceflight risks to health and human performance. Understanding and mitigating these risks is the focus of NASA s Human Research Program. However, NASA s approach to defining human research objectives is only one of many approaches within the ISS international partnership (including Roscosmos, the European Space Agency, the Canadian Space Agency, and the Japan Aerospace Exploration Agency). Each of these agencies selects and implements their own ISS research, with independent but related objectives for human and life sciences research. Because the science itself is also international and collaborative, investigations that are led by one ISS partner also often include cooperative scientists from around the world. The operation of the ISS generates significant additional data that is not directly linked to specific investigations. Such data comes from medical monitoring of crew members, life support and radiation monitoring, and from the systems that have been implemented to protect the health of the crew (such as exercise hardware). We provide examples of these international synergies in human research on ISS and highlight key early accomplishments that derive from these broad interfaces. Taken as a whole, the combination of diverse research objectives, operational data, international sharing of research resources on ISS, and scientific collaboration provide a robust research approach and capability that no one partner could achieve alone.

32 CFR 2004.11 - Agency Implementing Regulations, Internal Rules, or Guidelines [102(b)(3)].

Code of Federal Regulations, 2010 CFR

2010-07-01

... National Defense INFORMATION SECURITY OVERSIGHT OFFICE, NATIONAL ARCHIVES AND RECORDS ADMINISTRATION NATIONAL INDUSTRIAL SECURITY PROGRAM DIRECTIVE NO. 1 Implementation and Oversight § 2004.11 Agency...

Involvement of consumers in health technology assessment activities by Inahta agencies.

PubMed

Hailey, David; Werkö, Sophie; Bakri, Rugayah; Cameron, Alun; Göhlen, Britta; Myles, Susan; Pwu, Jasmine; Yothasamut, Jomkwan

2013-01-01

To obtain further information from members of the International Network of Agencies for Health Technology Assessment (INAHTA) on the involvement of consumers in their programs. A questionnaire for a survey was developed and sent to member agencies in November 2010. Survey responses were compared with those from an earlier survey conducted in 2005. Of the thirty-three agencies that provided responses, 67 percent involve consumers in some aspects of their health technology assessment (HTA) programs, compared with 57 percent in 2005. As in the earlier survey, most agencies reporting involvement have contact with consumer or patient organizations and a large minority also involve individual consumers. Summaries of HTA reports that are intended to be easily understood by consumers are prepared by 84 percent of the agencies, and 42 percent involve consumers in dissemination of HTA material. In both areas, there was some increase from the levels previously reported. The survey results suggest that there is a trend to increased involvement of consumers by the INAHTA agencies in their programs but that the level of involvement remains relatively limited. The manner of consumer participation varies between agencies.

Fighting ambient air pollution and its impact on health: from human rights to the right to a clean environment.

PubMed

Guillerm, N; Cesari, G

2015-08-01

Clean air is one of the basic requirements of human health and well-being. However, almost nine out of 10 individuals living in urban areas are affected by air pollution. Populations living in Africa, South-East Asia, and in low- and middle-income countries across all regions are the most exposed. Exposure to outdoor air pollution ranks as the ninth leading risk factor for mortality, killing 3.2 million people each year, especially young children, the elderly, persons with lung or cardiovascular disease, those who work or exercise outdoors and low-income populations. In October 2013, the International Agency for Research on Cancer (IARC) classified outdoor air pollution as carcinogenic to humans, calling air pollution 'a major environmental health problem'. Human rights and environmental norms are powerful tools to combat air pollution and its impact on health. The dependence of human rights on environmental quality has been recognised in international texts and by human rights treaty bodies. The growing awareness of the environment has already yielded considerable legislative and regulatory output. However, the implementation of standards remains a pervasive problem. In the fight against violations of norms, citizens have a crucial role to play. We discuss the relevance of a yet to be proclaimed standalone right to a healthy environment.

The Tale of Asbestos in Sweden 1972-1986-The Pathway to a Near-Total Ban.

PubMed

Westerholm, Peter; Remaéus, Bertil; Svartengren, Magnus

2017-11-22

This paper provides a narrative of the national intervention strategy in Sweden aimed to restrict the industrial use of asbestos. For many years, asbestos was imported for widespread industrial use, resulting in large amounts throughout Swedish society. In 1972, the whistle was blown in a Communist Party parliamentary motion describing asbestos as a health hazard and requesting action to prohibit its use. Although the motion was rejected, it initiated the extensive charting of asbestos sources on a tripartite basis, involving government agencies, and employer and trade-union organizations. Restrictive asbestos management practices were enforced from July 1982. The year 1985 saw the Government Asbestos Commission review, covering use-determining factors, international regulations, and assessments of cancer risks. The relative risks of chrysotile and amphibole were considered internationally (by the IARC), since chrysotile (a Canadian export) was regarded as unharmful in Canada at that time. Prohibiting asbestos use resulted in its virtual disappearance as an import to Sweden from the early 1980s. However, asbestos has undergone a transition from an occupational to a public-health hazard (although some work-related hazards, such as handling and disposal, remain). The transition reflects the public's exposure to existing stocks, in homes, workplaces, etc. Mesothelioma incidence has come to be regarded as an indicator of prevention effectiveness.

Extremely low-frequency magnetic fields of transformers and possible biological and health effects.

PubMed

Sirav, Bahriye; Sezgin, Gaye; Seyhan, Nesrin

2014-12-01

Physiological processes in organisms can be influenced by extremely low-frequency (ELF) electromagnetic energy. Biological effect studies have great importance; as well as measurement studies since they provide information on the real exposure situations. In this study, the leakage magnetic fields around a transformer were measured in an apartment building in Küçükçekmece, Istanbul, and the measurement results were evaluated with respect to the international exposure standards. The transformer station was on the bottom floor of a three-floor building. It was found that people living and working in the building were exposed to ELF magnetic fields higher than the threshold magnetic field value of the International Agency for Research on Cancer (IARC). Many people living in this building reported health complaints such as immunological problems of their children. There were child-workers working in the textile factories located in the building. Safe distances or areas for these people should be recommended. Protective measures could be implemented to minimize these exposures. Further residential exposure studies are needed to demonstrate the exposure levels of ELF magnetic fields. Precautions should, therefore, be taken either to reduce leakage or minimize the exposed fields. Shielding techniques should be used to minimize the leakage magnetic fields in such cases.

World Health Organization, radiofrequency radiation and health - a hard nut to crack (Review)

PubMed Central

Hardell, Lennart

2017-01-01

In May 2011 the International Agency for Research on Cancer (IARC) evaluated cancer risks from radiofrequency (RF) radiation. Human epidemiological studies gave evidence of increased risk for glioma and acoustic neuroma. RF radiation was classified as Group 2B, a possible human carcinogen. Further epidemiological, animal and mechanistic studies have strengthened the association. In spite of this, in most countries little or nothing has been done to reduce exposure and educate people on health hazards from RF radiation. On the contrary ambient levels have increased. In 2014 the WHO launched a draft of a Monograph on RF fields and health for public comments. It turned out that five of the six members of the Core Group in charge of the draft are affiliated with International Commission on Non-Ionizing Radiation Protection (ICNIRP), an industry loyal NGO, and thus have a serious conflict of interest. Just as by ICNIRP, evaluation of non-thermal biological effects from RF radiation are dismissed as scientific evidence of adverse health effects in the Monograph. This has provoked many comments sent to the WHO. However, at a meeting on March 3, 2017 at the WHO Geneva office it was stated that the WHO has no intention to change the Core Group. PMID:28656257

A critical review of the relationship between occupational exposure to diesel emissions and lung cancer risk.

PubMed

Möhner, Matthias; Wendt, Andrea

2017-03-01

In 2012, a working group of the International Agency for Research on Cancer classified diesel exhaust (DE) as a human carcinogen (Group 1). This decision was primarily based on the findings of the Diesel Exhaust in Miners Study (DEMS). The disparity between the results of various methodological approaches applied to the DEMS led to several critical commentaries. An expert panel was subsequently set up by the Health Effects Institute to evaluate the DEMS results, together with a large study in the trucking industry. The panel concluded that both studies provided a useful basis for quantitative risk assessments (QRAs) of DE exposure. However, the results of both studies were non-definitive as the studies suffer from several methodological shortcomings. We conducted a critical review of the studies used by the International Agency for Research on Cancer (IARC) working group to evaluate the relationship between DE and lung cancer. The aim was to assess whether the available studies support the statement of a causal relationship and, secondarily if they could be used for QRA. Our review highlights several methodological flaws in the studies, amongst them overadjustment bias, selection bias, and confounding bias. The conclusion from our review is that the currently published studies provide little evidence for a definite causal link between DE exposure and lung cancer risk. Based on two studies in miners, the DEMS and the German Potash Miners study, QRA may be conducted. However, the DEMS data should be reanalyzed in advance to avoid bias that affects the presently published risk estimates.

Forging Professional Learning Communities: The Role of External Agency

ERIC Educational Resources Information Center

Sperandio, Jill; Kong, Peggy A.

2018-01-01

This article explored the effects of external agency on the establishment of professional learning communities (PLCs). The research was undertaken in the context of schools that have chosen to adopt the Primary Years Programme (PYP) of the International Baccalaureate (IB) worldwide. The study employed a two-stage qualitative sequential design…

Justification of diagnostic medical exposures: some practical issues. Report of an International Atomic Energy Agency Consultation.

PubMed

Malone, J; Guleria, R; Craven, C; Horton, P; Järvinen, H; Mayo, J; O'reilly, G; Picano, E; Remedios, D; Le Heron, J; Rehani, M; Holmberg, O; Czarwinski, R

2012-05-01

The Radiation Protection of Patients Unit of the International Atomic Energy Agency (IAEA) is concerned about the effectiveness of justification of diagnostic medical exposures. Recent published work and the report of an initial IAEA consultation in the area gave grounds for such concerns. There is a significant level of inappropriate usage, and, in some cases, a poor level of awareness of dose and risk among some key groups involved. This article aims to address this. The IAEA convened a second group of experts in November 2008 to review practical and achievable actions that might lead to more effective justification. This report summarises the matters that this group considered and the outcome of their deliberations. There is a need for improved communication, both within professions and between professionals on one hand, and between professionals and the patients/public on the other. Coupled with this, the issue of consent to imaging procedures was revisited. The need for good evidence-based referral guidelines or criteria of acceptability was emphasised, as was the need for their global adaptation and dissemination. Clinical audit was regarded as a key tool in ensuring that justification becomes an effective, transparent and accountable part of normal radiological practice. In summary, justification would be facilitated by the "3 As": awareness, appropriateness and audit.

ATHLETE: Lunar Cargo Handling for International Lunar Exploration

NASA Technical Reports Server (NTRS)

Wilcox, Brian H.

2010-01-01

As part of the Human-Robot Systems Project within the NASA Exploration Technology Development Program, the Jet Propulsion Laboratory is developing a vehicle called ATHLETE: the All-Terrain Hex-Limbed Extra-Terrestrial Explorer. The basic idea of ATHLETE is to have six relatively small wheels on the ends of legs. The small wheels and associated drive actuators are much less massive than the larger wheels and gears needed for an "all terrain" vehicle that cannot "walk" out of extreme terrain. The mass savings for the wheels and wheel actuators is greater than the mass penalty of the legs, for a net mass savings. Starting in 2009, NASA became engaged in detailed architectural studies for international discussions with the European Space Agency (ESA), the Japanese Space Agency (JAXA), and the Canadian Space Agency (CSA) under the auspices of the International Architecture Working Group (IAWG). ATHLETE is considered in most of the campaign options considered, providing a way to offload cargo from large Altair-class landers (having a cargo deck 6+ meters above the surface) as well as offloading international landers launched on Ariane-5 or H-2 launch vehicles. These international landers would carry provisions as well as scientific instruments and/or small rovers that would be used by international astronauts as part of an international effort to explore the moon.Work described in this paper includes architectural studies in support of the international missions as well as field testing of a half-scale ATHLETE prototype performing cargo offloading from a lander mockup, along with multi-kilometer traverse, climbing over greater than 1 m rocks, tool use, etc.

International petroleum statistics report

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The International Petroleum Statistics Report is a monthly publication that provides current international oil data. This report is published for the use of Members of Congress, Federal agencies, State agencies, industry, and the general public. Publication of this report is in keeping with responsibilities given the Energy Information Administration in Public Law 95-91. The International Petroleum Statistics Report presents data on international oil production, demand, imports, and stocks. The report has four sections. Section 1 contains time series data on world oil production, and on oil demand and stocks in the Organization for Economic Cooperation and Development (OECD). This sectionmore » contains annual data beginning in 1985, and monthly data for the most recent two years. Section 2 presents an oil supply/demand balance for the world. This balance is presented in quarterly intervals for the most recent two years. Section 3 presents data on oil imports by OECD countries. This section contains annual data for the most recent year, quarterly data for the most recent two quarters, and monthly data for the most recent twelve months. Section 4 presents annual time series data on world oil production and oil stocks, demand, and trade in OECD countries. World oil production and OECD demand data are for the years 1970 through 1995; OECD stocks from 1973 through 1995; and OECD trade from 1985 through 1995.« less

The role of education in the celebration of International Space Year

NASA Technical Reports Server (NTRS)

Owens, Frank C.; Mcgee, A. S.

1991-01-01

NASA's role in International Space Year (ISY) educational activities is described. The Agency is a coleader of the space agency forum panel of experts on education and applications, a developer of educational activities within the agency, and a facilitator of ISY-related activities in the public and private sectors in the USA.

IPDA PDS4 Project: Towards an International Planetary Data Standard

NASA Astrophysics Data System (ADS)

Martinez, Santa; Roatsch, Thomas; Capria, Maria Teresa; Heather, David; Yamamoto, Yukio; Hughes, Steven; Stein, Thomas; Cecconi, Baptiste; Prashar, Ajay; Batanov, Oleg; Gopala Krishna, Barla

2016-07-01

The International Planetary Data Alliance (IPDA) is an international collaboration of space agencies with the main objective of facilitating discovery, access and use of planetary data managed across international boundaries. For this purpose, the IPDA has adopted the NASA's Planetary Data System (PDS) standard as the de-facto archiving standard, and is working towards the internationalisation of the new generation of the standards, called PDS4. PDS4 is the largest upgrade in the history of the PDS, and is a significant step towards an online, distributed, model-driven and service-oriented architecture international archive. Following the successful deployment of PDS4 to support NASA's LADEE and MAVEN missions, PDS4 was endorsed by IPDA in 2014. This has led to the adoption of PDS4 by a number of international space agencies (ESA, JAXA, ISRO and Roscosmos, among others) for their upcoming missions. In order to closely follow the development of the PDS4 standards and to coordinate the international contribution and participation in its evolution, a group of experts from each international agency is dedicated to review different aspects of the standards and to capture recommendations and requirements to ensure the international needs are met. The activities performed by this group cover the assessment and implementation of all aspects of PDS4, including its use, documentation, tools, validation strategies and information model. This contribution will present the activities carried out by this group and how this partnership between PDS and IPDA provides an excellent foundation towards an international platform for planetary science research.

My action lasts longer: Potential link between subjective time and agency during voluntary action.

PubMed

Imaizumi, Shu; Asai, Tomohisa

2017-05-01

Time perception distorts across different phases of bodily movement. During motor execution, sensory feedback matching an internal sensorimotor prediction is perceived to last longer. The sensorimotor prediction also underlies sense of agency. We investigated association between subjective time and agency during voluntary action. Participants performed hand action while watching a video feedback of their hand with various delays to manipulate agency. The perceived duration and agency over the video feedback were judged. Minimal delay of the video feedback resulted in longer perceived duration than the actual duration and stronger agency, while substantial feedback delay resulted in shorter perceived duration and weaker agency. These fluctuations of perceived duration and agency were nullified by the feedback of other's hand instead of their own, but not by inverted feedback from a third-person perspective. Subjective time during action might be associated with agency stemming from sensorimotor prediction, and self-other distinction based on bodily appearance. Copyright © 2017 Elsevier Inc. All rights reserved.

A Critical Analysis of the INQAAHE Guidelines of Good Practice for Higher Education Quality Assurance Agencies

ERIC Educational Resources Information Center

Blackmur, Douglas

2008-01-01

The International Network of Quality Assurance Agencies in Higher Education's Guidelines of Good Practice by higher education quality assurance agencies need substantial revision before they can be considered adequate by stakeholders in any national higher education system. Various revisions are proposed in this article. But the International…

Compensating Controls and Agency Conflicts in the Absence of Owners: The Case of Nonprofit Charter Schools

ERIC Educational Resources Information Center

Bradley, Jean Ryberg

2017-01-01

This dissertation consists of three essays using publicly reported internal control deficiencies to examine agency conflicts in the unique organizational setting provided by nonprofit charter schools. In my first essay, I find evidence that increased agency conflicts in nonprofit charter schools are "not" associated with increased…

Extension of the International Atomic Energy Agency phantom study in image quantification: results of multicentre evaluation in Croatia.

PubMed

Grošev, Darko; Gregov, Marin; Wolfl, Miroslava Radić; Krstonošić, Branislav; Debeljuh, Dea Dundara

2018-06-07

To make quantitative methods of nuclear medicine more available, four centres in Croatia participated in the national intercomparison study, following the materials and methods used in the previous international study organized by the International Atomic Energy Agency (IAEA). The study task was to calculate the activities of four Ba sources (T1/2=10.54 years; Eγ=356 keV) using planar and single-photon emission computed tomography (SPECT) or SPECT/CT acquisitions of the sources inside a water-filled cylindrical phantom. The sources were previously calibrated by the US National Institute of Standards and Technology. Triple-energy window was utilized for scatter correction. Planar studies were corrected for attenuation correction (AC) using the conjugate-view method. For SPECT/CT studies, data from X-ray computed tomography were used for attenuation correction (CT-AC), whereas for SPECT-only acquisition, the Chang-AC method was applied. Using the lessons learned from the IAEA study, data were acquired according to the harmonized data acquisition protocol, and the acquired images were then processed using centralized data analysis. The accuracy of the activity quantification was evaluated as the ratio R between the calculated activity and the value obtained from National Institute of Standards and Technology. For planar studies, R=1.06±0.08; for SPECT/CT study using CT-AC, R=1.00±0.08; and for Chang-AC, R=0.89±0.12. The results are in accordance with those obtained within the larger IAEA study and confirm that SPECT/CT method is the most appropriate for accurate activity quantification.

22 CFR 1101.14 - Appeal of agency decision not to correct or amend a record.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Appeal of agency decision not to correct or amend a record. 1101.14 Section 1101.14 Foreign Relations INTERNATIONAL BOUNDARY AND WATER COMMISSION, UNITED STATES AND MEXICO, UNITED STATES SECTION PRIVACY ACT OF 1974 § 1101.14 Appeal of agency decision...

22 CFR 1101.14 - Appeal of agency decision not to correct or amend a record.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Appeal of agency decision not to correct or amend a record. 1101.14 Section 1101.14 Foreign Relations INTERNATIONAL BOUNDARY AND WATER COMMISSION, UNITED STATES AND MEXICO, UNITED STATES SECTION PRIVACY ACT OF 1974 § 1101.14 Appeal of agency decision...

Government control over health-related not-for-profit organisations: Agency for International Development v. Alliance for Open Society International Inc 570 US_(2013).

PubMed

Vines, Tim; Donohoo, Angus M; Faunce, Thomas

2013-12-01

The relationship between government and the not-for-profit (NFP) sector has important implications for society, especially in relation to the delivery of public health measures and the protection of the environment. In key health-related areas such as provision of medical services, welfare, foreign aid and education, governments have traditionally preferred for the NFP sector to act as service partners, with the relationship mediated through grants or funding agreements. This service delivery arrangement is intended to provide a diversity of voices, and encourage volunteerism and altruism, in conjunction with the purposes and objectives of the relevant NGO. Under the pretence of "accountability", however, governments increasingly are seeking to impose intrusive conditions on grantees, which limit their ability to fulfil their mission and advocate on behalf of their constituents. This column examines the United States Supreme Court decision, Agency for International Development v Alliance for Open Society International Inc 570 US_(2013), and compares it to the removal of gag clauses in Australian federal funding rules. Recent national changes to the health-related NFP sector in Australia are then discussed, such as those found in the Charities Act 2013 (Cth) and the Not-for-Profit Sector Freedom to Advocate Act 2013 (Cth). These respectively include the establishment of the Australian Charities and Not-For-Profit Commission, the modernising of the definition of "charity" and statutory blocks on "gag" clauses. This analysis concludes with a survey of recent moves by Australian States to impose new restrictions on the ability of health-related NFPs to lobby against harmful government policy Among the responses considered is the protection afforded by s 51l(xxiiiA) of the Australian Constitution. This constitutional guarantee appears to have been focused historically on preventing medical and dental practitioners and related small businesses being practically coerced

78 FR 14518 - Agency Information Collection Activities; Comment Request; Program for the International...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-06

... DEPARTMENT OF EDUCATION [Docket No. ED-2013-ICCD-0021] Agency Information Collection Activities... information collection. DATES: Interested persons are invited to submit comments on or before May 6, 2013... information or comments submitted by postal mail or delivery should be addressed to the Director of the...

78 FR 143 - Notice of Solicitation of Public and Federal Agency Comments for Collaboration on Evaluating the...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-02

... Federal Agency Comments for Collaboration on Evaluating the World Health Organization (WHO) International... the business processes of other Federal agencies and researchers throughout the world. We invite other...-CY reflect WHO's framework for measuring health and disability at both individual and population...

76 FR 51123 - Agency Information Collection Activities; Submission for OMB Review and Approval; Joint Comment...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-17

... clearly the definition of capital used in any aspect of its internal capital adequacy assessment process (ICAAP) and document any changes in the internal definition of capital. Section 41 requires banks to... regulatory or accounting). The agencies' burden estimates for these information collection requirements are...

Using an international p53 mutation database as a foundation for an online laboratory in an upper level undergraduate biology class.

PubMed

Melloy, Patricia G

2015-01-01

A two-part laboratory exercise was developed to enhance classroom instruction on the significance of p53 mutations in cancer development. Students were asked to mine key information from an international database of p53 genetic changes related to cancer, the IARC TP53 database. Using this database, students designed several data mining activities to look at the changes in the p53 gene from a number of perspectives, including potential cancer-causing agents leading to particular changes and the prevalence of certain p53 variations in certain cancers. In addition, students gained a global perspective on cancer prevalence in different parts of the world. Students learned how to use the database in the first part of the exercise, and then used that knowledge to search particular cancers and cancer-causing agents of their choosing in the second part of the exercise. Students also connected the information gathered from the p53 exercise to a previous laboratory exercise looking at risk factors for cancer development. The goal of the experience was to increase student knowledge of the link between p53 genetic variation and cancer. Students also were able to walk a similar path through the website as a cancer researcher using the database to enhance bench work-based experiments with complementary large-scale database p53 variation information. © 2014 The International Union of Biochemistry and Molecular Biology.

Operating Reserves and Wind Power Integration: An International Comparison; Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Milligan, M.; Donohoo, P.; Lew, D.

2010-10-01

This paper provides a high-level international comparison of methods and key results from both operating practice and integration analysis, based on an informal International Energy Agency Task 25: Large-scale Wind Integration.

The International Epidemiology of Lung Cancer: Latest Trends, Disparities, and Tumor Characteristics

PubMed Central

Cheng, Ting-Yuan David; Cramb, Susanna M.; Baade, Peter D.; Youlden, Danny R.; Nwogu, Chukwumere; Reid, Mary E.

2017-01-01

Introduction We aim to update global lung cancer epidemiology and describe changing trends and disparities. Methods We presented country-specific incidence and mortality from GLOBOCAN 2012, by region and socioeconomic factors via the Human Development Index (HDI). Between- and within-country incidence by histological type was analyzed from Cancer Incidence in Five Continents Volume X (IARC). Trend analyses including the IARC data, cancer registries, and the WHO Mortality database were conducted using Joinpoint regression. Survival was compared between and within countries, and by histology. Results In 2012, there were 1.82 and 1.59 million new cases and deaths of lung cancer worldwide, respectively. Incidence was highest in very high HDI countries and lowest in low HDI countries (42.2 vs. 7.9/100,000 for males and 21.8 vs. 3.1/100,000 for females, respectively). In most countries with a very high HDI, as male incidence decreased gradually (ranging from −0.3% in Spain to −2.5% in the USA each year), female incidence continued to increase (by 1.4% each year in Australia to 6.1% in recent years in Spain). While histology varied between countries, adenocarcinoma was more common than squamous cell carcinoma, particularly among females (e.g., in Chinese females, the adenocarcinoma-to-squamous cell carcinoma ratio=6.6). Five-year relative survival varied from 2% (Libya) to 30% (Japan), with substantial within-country differences. Conclusion Lung cancer will continue to be a major health problem well through the first half of this century. Preventive strategies, particularly tobacco control, tailored to populations at highest risk are key to reduce the global burden of lung cancer. PMID:27364315

32 CFR 728.57 - Department of State and associated agencies.

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Department of Justice—Drug Enforcement Agency. (10) Department of Treasury—U.S. Customs, U.S. Secret Service... (JECOR), and the Internal Revenue Service. (11) National Aeronautics and Space Administration. (12... State Medical Program. (b) Care authorized—(1) General. The Foreign Service Act of 1946, as amended...

17th International Microgravity Measurements Group Meeting

NASA Technical Reports Server (NTRS)

DeLombard, Richard

1998-01-01

The Seventeenth International Microgravity Measurements Group (MGMG) meeting was held 24-26 March 1998 at the Ohio Aerospace Institute (OAI) in Brook Park, Ohio. This meeting focused on the transition of microgravity science research from the Shuttle, Mir, and free flyers to the International Space Station. The MGMG series of meetings are conducted by the Principal Investigator Microgravity Services project of the Microgravity Science Division at the NASA Lewis Research Center. The MGMG meetings provide a forum for the exchange of information and ideas about the microgravity environment and microgravity acceleration research in the Microgravity Research Program. The meeting had participation from investigators in all areas of microgravity research. The attendees included representatives from: NASA centers; National Space Development Agency of Japan; European Space Agency; Daimler Benz Aerospace AG; Deutsches Zentrum fuer Luft- und Raumfahrt; Centre National d'Etudes Spatiales; Canadian Space Agency, national research institutions; Universities in U.S., Italy, Germany, and Russia; and commercial companies in the U.S. and Russia. Several agencies presented summaries of the measurement, analysis, and characterization of the microgravity environment of the Shuttle, Mir, and sounding rockets over the past fifteen years. This extensive effort has laid a foundation for pursuing a similar course during future microgravity science experiment operations on the ISS. Future activities of microgravity environment characterization were discussed by several agencies who plan to operate on the ISS.

International nuclear fuel cycle fact book. Revision 4

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harmon, K.M.; Lakey, L.T.; Leigh, I.W.

This Fact Book has been compiled in an effort to provide (1) an overview of worldwide nuclear power and fuel cycle programs and (2) current data concerning fuel cycle and waste management facilities, R and D programs, and key personnel in countries other than the United States. Additional information on each country's program is available in the International Source Book: Nuclear Fuel Cycle Research and Development, PNL-2478, Rev. 2. The Fact Book is organized as follows: (1) Overview section - summary tables which indicate national involvement in nuclear reactor, fuel cycle, and waste management development activities; (2) national summaries -more » a section for each country which summarizes nuclear policy, describes organizational relationships and provides addresses, names of key personnel, and facilities information; (3) international agencies - a section for each of the international agencies which has significant fuel cycle involvement; (4) energy supply and demand - summary tables, including nuclear power projections; (5) fuel cycle - summary tables; and (6) travel aids - international dialing instructions, international standard time chart, passport and visa requirements, and currency exchange rate.« less

International Nuclear Fuel Cycle Fact Book. Revision 5

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harmon, K.M.; Lakey, L.T.; Leigh, I.W.

This Fact Book has been compiled in an effort to provide: (1) an overview of worldwide nuclear power and fuel cycle programs; and (2) current data concerning fuel cycle and waste management facilities, R and D programs, and key personnel in countries other than the United States. Additional information on each country's program is available in the International Source Book: Nuclear Fuel Cycle Research and Development, PNL-2478, Rev. 2. The Fact Book is organized as follows: (1) Overview section - summary tables which indicate national involvement in nuclear reactor, fuel cycle, and waste management development activities; (2) national summaries -more » a section for each country which summarizes nuclear policy, describes organizational relationships and provides addresses, names of key personnel, and facilities information; (3) international agencies - a section for each of the international agencies which has significant fuel cycle involvement; (4) energy supply and demand - summary tables, including nuclear power projections; (5) fuel cycle - summary tables; and (6) travel aids international dialing instructions, international standard time chart, passport and visa requirements, and currency exchange rate.« less

Judgements of agency in schizophrenia: an impairment in autonoetic metacognition.

PubMed

Metcalfe, Janet; Van Snellenberg, Jared X; DeRosse, Pamela; Balsam, Peter; Malhotra, Anil K

2012-05-19

We investigated judgements of agency in participants with schizophrenia and healthy controls. Participants engaged in a computer game in which they attempted to touch downward falling Xs and avoid touching Os. On some trials, participants were objectively in perfect control. On other trials, they were objectively not in complete control because the movement of the cursor on the screen was distorted with respect to the position of the mouse by random noise (turbulence), or it was lagged by 250 or 500 ms. Participants made metacognitive judgements of agency as well as judgements of performance. Control participants' judgements of agency were affected by the turbulence and lag variables-indicating that they knew they were objectively not in control in those conditions, and they were also influenced by their assessments of performance. The patients also used their assessments of performance but neither turbulence nor lag affected their judgements of agency. This indicated an impairment in agency monitoring. The patients, unlike the healthy controls, used only publically available external cues about performance in making judgements of 'agency' and did not rely on any additional access to internal self-relevant cues that were diagnostic in indicating whether or not they were, in fact, in control.

75 FR 54299 - Notice of Public Information Collections Being Reviewed by the U.S. Agency for International...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-07

... with the nongovernmental organization (NGO) community at large. In order to better coordinate the Agency's work with NGOs and to improve the effectiveness and extent of the Agency's outreach to the NGO community, the CFBCI is requesting to send out a voluntary, electronic survey to contacts with NGOs who have...

International Standardization of Bed Rest Standard Measures

NASA Technical Reports Server (NTRS)

Cromwell, Ronita L.

2010-01-01

This slide presentation gives an overview of the standardization of bed rest measures. The International Countermeasures Working Group attempted to define and agree internationally on standard measurements for spaceflight based bed rest studies. The group identified the experts amongst several stakeholder agencys. It included information on exercise, muscle, neurological, psychological, bone and cardiovascular measures.

Complex negotiations: the lived experience of enacting agency after a stroke.

PubMed

Bergström, Aileen L; Eriksson, Gunilla; Asaba, Eric; Erikson, Anette; Tham, Kerstin

2015-01-01

This qualitative, longitudinal, descriptive study aimed to understand the lived experience of enacting agency, and to describe the phenomenon of agency and the meaning structure of the phenomenon during the year after a stroke. Agency is defined as making things happen in everyday life through one's actions. This study followed six persons (three men and three women, ages 63 to 89), interviewed on four separate occasions. Interview data were analysed using the Empirical Phenomenological Psychological method. The main findings showed that the participants experienced enacting agency in their everyday lives after stroke as negotiating different characteristics over a span of time, a range of difficulty, and in a number of activities, making these negotiations complex. The four characteristics described how the participants made things happen in their everyday lives through managing their disrupted bodies, taking into account their past and envisioning their futures, dealing with the world outside themselves, and negotiating through internal dialogues. This empirical evidence regarding negotiations challenges traditional definitions of agency and a new definition of agency is proposed. Understanding clients' complex negotiations and offering innovative solutions to train in real-life situations may help in the process of enabling occupations after a stroke.

Synthesizing International Understanding of Changes in the Arctic Hydrological System

NASA Astrophysics Data System (ADS)

Pundsack, J. W.; Vorosmarty, C. J.; Hinzman, L. D.

2009-12-01

There are several notable gaps in our current level of understanding of Arctic hydrological systems. At the same time, rapidly emerging data sets, technologies, and modeling resources provide us with an unprecedented opportunity to move substantially forward. The Arctic Community-Wide Hydrological Analysis and Monitoring Program (Arctic-CHAMP), funded by NSF/ARCSS, was established to initiate a major effort to improve our current monitoring of water cycle variables, and to foster collaboration with the many relevant U.S. and international arctic research initiatives. These projects, funded under ARCSS through the ‘Freshwater Integration (FWI) study’, links CHAMP, the Arctic/Subarctic Ocean Fluxes (ASOF) Programme, and SEARCH. As part of the overall synthesis and integration efforts of the NSF-ARCSS Freshwater Integration (FWI) study, the program carried-out a major International Synthesis Capstone Workshop in Fall 2009 as an International Polar Year (IPY) affiliated meeting. The workshop, "Synthesizing International Understanding of Changes in the Arctic Hydrological System,” was held 30 September to 4 October 2009 in Stockholm at the Beijer Auditorium of the Royal Swedish Academy. The workshop was sponsored by the NSF-ARCSS Arctic-CHAMP Science Management Office (City College of New York / Univ. of New Hampshire), the International Study of Arctic Change (ISAC), and the International Arctic Research Center (IARC; Univ. of Alaska Fairbanks). The overarching goals of the meeting were to stage a post-IPY lessons-learned workshop with co-equal numbers of FWI, IPY, and ICARP-II researchers, using insights from recent scientific findings, data, and strategies to afford synthesis. The workshop aimed to: (1) take stock of recent advances in our understanding of changes in the Arctic hydrological system; (2) identify key remaining research gaps / unanswered questions; and (3) gather insight on where to focus future research efforts/initiatives (nationally and

45 CFR 630.645 - Federal agency or agency.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 3 2010-10-01 2010-10-01 false Federal agency or agency. 630.645 Section 630.645 Public Welfare Regulations Relating to Public Welfare (Continued) NATIONAL SCIENCE FOUNDATION GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) Definitions § 630.645 Federal agency...

48 CFR 2917.504-70 - Signature authority and internal procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... The Economy Act 2917.504-70 Signature authority and internal procedures. (a) A DOL contracting officer, HCA, Agency Head, or another official designated by the Assistant Secretary for Administration and... the signing of all new Federal Interagency Agreements and deleting expired agreements. (c) Agencies...

The need for independent research on the health effects of glyphosate-based herbicides.

PubMed

Landrigan, Philip J; Belpoggi, Fiorella

2018-05-29

Glyphosate, formulated as Roundup, is the world's most widely used herbicide. Glyphosate is used extensively on genetically modified (GM) food crops designed to tolerate the herbicide, and global use is increasing rapidly. Two recent reviews of glyphosate's health hazards report conflicting results. An independent review by the International Agency for Research on Cancer (IARC) found that glyphosate is a "probable human carcinogen". A review by the European Food Safety Agency (EFSA) found no evidence of carcinogenic hazard. These differing findings have produced regulatory uncertainty. Reflecting this regulatory uncertainty, the European Commission on November 27 2017, extended authorization for glyphosate for another 5 years, while the European Parliament opposed this decision and issued a call that pesticide approvals be based on peer-reviewed studies by independent scientists rather than on the current system that relies on proprietary industry studies. The Ramazzini Institute has initiated a pilot study of glyphosate's health hazards that will be followed by an integrated experimental research project. This evaluation will be independent of industry support and entirely sponsored by worldwide crowdfunding. The aim of the Ramazzini Institute project is to explore comprehensively the effects of exposures to glyphosate-based herbicides at current real-world levels on several toxicological endpoints, including carcinogenicity, long-term toxicity, neurotoxicity, endocrine disrupting effects, prenatal developmental toxicity, the microbiome and multi-generational effects.

Comprehensive review on toxicity of persistent organic pollutants from petroleum refinery waste and their degradation by microorganisms.

PubMed

Varjani, Sunita J; Gnansounou, Edgard; Pandey, Ashok

2017-12-01

Control and prevention of environmental pollution has become a worldwide issue of concern. Aromatic hydrocarbons including benzene, toluene, ethyl benzene, xylene (BTEX) and polyaromatic hydrocarbons (PAHs) are persistent organic pollutants (POPs), released into the environment mainly by exploration activities of petroleum industry. These pollutants are mutagenic, carcinogenic, immunotoxic and teratogenic to lower and higher forms of life i.e. microorganisms to humans. According to the International Agency for Research on Cancer (IARC) and United States Environmental Protection Agency (U.S. EPA), Benzo[a]pyrene (BaP) is carcinogenic in laboratory animals and humans. Aromatic hydrocarbons are highly lipid soluble and thus readily absorbed from environment in gastrointestinal tract of mammals. Treatment and remediation of petroleum refinery waste have been shown either to reduce or to eliminate genotoxicity of these pollutants. Bioremediation by using microorganisms to treat this waste is showing a promising technology as it is safe and cost-effective option among various technologies tested. The main aim of this review is to provide contemporary information on variety of aromatic hydrocarbons present in crude oil (with special focus to mono- and poly-aromatic hydrocarbons), exposure routes and their adverse effects on humans. This review also provides a synthesis of scientific literature on remediation technologies available for aromatic hydrocarbons, knowledge gaps and future research developments in this field. Copyright © 2017 Elsevier Ltd. All rights reserved.

22 CFR 202.8 - Refund by suppliers and/or agencies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... Section 202.8 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT OVERSEAS SHIPMENTS OF SUPPLIES BY... demand the entire amount, or any lesser amount specified, of such freight charges determined by AID to be... charges have been paid or reimbursed under this Regulation will promptly refund to AID upon demand the...

22 CFR 120.5 - Relation to regulations of other agencies.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Relation to regulations of other agencies. 120.5 Section 120.5 Foreign Relations DEPARTMENT OF STATE INTERNATIONAL TRAFFIC IN ARMS REGULATIONS... General collectively comprise the U.S. Munitions List under the Arms Export Control Act (AECA). As the...

77 FR 1043 - Airworthiness Directives; Honeywell International Inc. Turbofan Engines

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-09

... International Inc. Turbofan Engines AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of... Honeywell International Inc. TFE731-20R, -20AR, -20BR, -40, -40AR, -40R, -50R, and -60 turbofan engines. (i...

Training the Future - Interns Harvesting & Testing Plant Experim

NASA Image and Video Library

2017-07-19

In the Space Life Sciences Laboratory at NASA's Kennedy Space Center in Florida, student interns such as Alex Litvin are joining agency scientists, contributing in the area of plant growth research for food production in space. Litvin is pursuing doctorate in horticulture at Iowa State University. The agency attracts its future workforce through the NASA Internship, Fellowships and Scholarships, or NIFS, Program.

Disaster response and the international charter program

USGS Publications Warehouse

Stryker, Timothy; Jones, Brenda

2009-01-01

In a meeting held in Vienna, Austria in 1999, a small group of space agencies conceived and approved a program to provide emergency response satellite data to those affected by disasters anywhere in the world. The purpose of this group, which came to be known as the “International Charter - Space and Major Disasters”, is to promote cooperation among space agencies in the use of satellite data to manage crises during and after disasters. When tropical storms, floods, oil spills, earthquakes, landslides, volcanoes or fires endanger human life, the Charter member agencies provide valuable information about these events’ extent and impact.

Regulatory accountability: Telecommunications and electricity agencies in the United Kingdom, France and Sweden

NASA Astrophysics Data System (ADS)

Rubinstein, Dorit

2007-12-01

This dissertation examines how administrative agencies deal with multiple and conflicting accountability pressures. Drawing on an empirical study of six agencies, the telecommunications and electricity regulators of the UK, France and Sweden, it describes how the agencies legitimized their behavior in relation to three major issues, network pricing, universal service and retail competition. I find that agencies use different forms of accountability in different circumstances, and suggest a classification of accountability strategies along two dimensions: internalizing v. externalizing authority, and the breadth of the target audience. What explains variations along these dimensions is the task characteristics of the issue an agency is dealing with, and specifically, its informational aspects and the degree of political controversy associated with it. The more an issue requires expertise, the more an agency will seek to rely on its professional judgment. The more an issue can be addressed only in terms of the values surrounding it, the more an agency will seek to externalize authority and defer to other actors. Also, the more politically controversial an issue, the broader the target audience before whom an agency will try to justify itself.

2 CFR 1401.245 - Federal agency or agency.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Federal agency or agency. 1401.245 Section 1401.245 Grants and Agreements Federal Agency Regulations for Grants and Agreements DEPARTMENT OF THE INTERIOR REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) (Eff. 1-21-2011) Definitions § 1401...

Contribution of the Japan International Cooperation Agency health-related projects to health system strengthening

PubMed Central

2013-01-01

Background The Japan International Cooperation Agency (JICA) has focused its attention on appraising health development assistance projects and redirecting efforts towards health system strengthening. This study aimed to describe the type of project and targets of interest, and assess the contribution of JICA health-related projects to strengthening health systems worldwide. Methods We collected a web-based Project Design Matrix (PDM) of 105 JICA projects implemented between January 2005 and December 2009. We developed an analytical matrix based on the World Health Organization (WHO) health system framework to examine the PDM data and thereby assess the projects’ contributions to health system strengthening. Results The majority of JICA projects had prioritized workforce development, and improvements in governance and service delivery. Conversely, there was little assistance for finance or medical product development. The vast majority (87.6%) of JICA projects addressed public health issues, for example programs to improve maternal and child health, and the prevention and treatment of infectious diseases such as AIDS, tuberculosis and malaria. Nearly 90% of JICA technical healthcare assistance directly focused on improving governance as the most critical means of accomplishing its goals. Conclusions Our study confirmed that JICA projects met the goals of bilateral cooperation by developing workforce capacity and governance. Nevertheless, our findings suggest that JICA assistance could be used to support financial aspects of healthcare systems, which is an area of increasing concern. We also showed that the analytical matrix methodology is an effective means of examining the component of health system strengthening to which the activity and output of a project contributes. This may help policy makers and practitioners focus future projects on priority areas. PMID:24053583

Contribution of the Japan International Cooperation Agency health-related projects to health system strengthening.

PubMed

Yuasa, Motoyuki; Yamaguchi, Yoshie; Imada, Mihoko

2013-09-22

The Japan International Cooperation Agency (JICA) has focused its attention on appraising health development assistance projects and redirecting efforts towards health system strengthening. This study aimed to describe the type of project and targets of interest, and assess the contribution of JICA health-related projects to strengthening health systems worldwide. We collected a web-based Project Design Matrix (PDM) of 105 JICA projects implemented between January 2005 and December 2009. We developed an analytical matrix based on the World Health Organization (WHO) health system framework to examine the PDM data and thereby assess the projects' contributions to health system strengthening. The majority of JICA projects had prioritized workforce development, and improvements in governance and service delivery. Conversely, there was little assistance for finance or medical product development. The vast majority (87.6%) of JICA projects addressed public health issues, for example programs to improve maternal and child health, and the prevention and treatment of infectious diseases such as AIDS, tuberculosis and malaria. Nearly 90% of JICA technical healthcare assistance directly focused on improving governance as the most critical means of accomplishing its goals. Our study confirmed that JICA projects met the goals of bilateral cooperation by developing workforce capacity and governance. Nevertheless, our findings suggest that JICA assistance could be used to support financial aspects of healthcare systems, which is an area of increasing concern. We also showed that the analytical matrix methodology is an effective means of examining the component of health system strengthening to which the activity and output of a project contributes. This may help policy makers and practitioners focus future projects on priority areas.

Justification of diagnostic medical exposures: some practical issues. Report of an International Atomic Energy Agency Consultation

PubMed Central

Malone, J; Guleria, R; Craven, C; Horton, P; Järvinen, H; Mayo, J; O’reilly, G; Picano, E; Remedios, D; Le Heron, J; Rehani, M; Holmberg, O; Czarwinski, R

2012-01-01

Objectives The Radiation Protection of Patients Unit of the International Atomic Energy Agency (IAEA) is concerned about the effectiveness of justification of diagnostic medical exposures. Recent published work and the report of an initial IAEA consultation in the area gave grounds for such concerns. There is a significant level of inappropriate usage, and, in some cases, a poor level of awareness of dose and risk among some key groups involved. This article aims to address this. Methods The IAEA convened a second group of experts in November 2008 to review practical and achievable actions that might lead to more effective justification. Results This report summarises the matters that this group considered and the outcome of their deliberations. There is a need for improved communication, both within professions and between professionals on one hand, and between professionals and the patients/public on the other. Coupled with this, the issue of consent to imaging procedures was revisited. The need for good evidence-based referral guidelines or criteria of acceptability was emphasised, as was the need for their global adaptation and dissemination. Conclusion Clinical audit was regarded as a key tool in ensuring that justification becomes an effective, transparent and accountable part of normal radiological practice. In summary, justification would be facilitated by the “3 As”: awareness, appropriateness and audit. PMID:21343316

Hiring & Retaining More Women: The Advantages to Law Enforcement Agencies.

ERIC Educational Resources Information Center

Lonsway, Kimberly A.

Hiring and retaining more women provides numerous important advantages to law enforcement agencies. Research conducted in the United States and internationally has clearly documented that following facts: (1) female officers are as competent as their male counterparts and even excel in certain areas of police performance; (2) female officers are…

22 CFR 1101.14 - Appeal of agency decision not to correct or amend a record.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Appeal of agency decision not to correct or amend a record. 1101.14 Section 1101.14 Foreign Relations INTERNATIONAL BOUNDARY AND WATER COMMISSION, UNITED STATES AND MEXICO, UNITED STATES SECTION PRIVACY ACT OF 1974 § 1101.14 Appeal of agency decision not to correct or amend a record. (a) An appea...

International Space Station (ISS)

NASA Image and Video Library

2007-08-01

As the construction continued on the International Space Station (ISS), STS-118 Astronaut Dave Williams, representing the Canadian Space Agency, participated in the fourth and final session of Extra Vehicular Activity (EVA). During the 5 hour space walk, Williams and Expedition 15 engineer Clay Anderson (out of frame) installed the External Wireless Instrumentation System Antenna, attached a stand for the shuttle robotic arm extension boom, and retrieved the two Materials International Space Station Experiments (MISSE) for return to Earth. MISSE collects information on how different materials weather in the environment of space.

19 CFR 210.78 - Notice of enforcement action to Government agencies.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 19 Customs Duties 3 2010-04-01 2010-04-01 false Notice of enforcement action to Government agencies. 210.78 Section 210.78 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE ADJUDICATION AND ENFORCEMENT Enforcement Procedures and Advisory...

Agency Governance and Enforcement: The Influence of Mission on Environmental Decisionmaking

ERIC Educational Resources Information Center

Firestone, Jeremy

2002-01-01

Administrative agencies seeking to impose sanctions for regulatory violations can handle matters internally or through civil or criminal courts. Organizational culture, legal constraints, and political and private actors may influence governance and hence choice of enforcement venue. An enforcement behavior model is constructed and tested…

78 FR 66964 - International Space Station Advisory Committee; Charter Renewal

Federal Register 2010, 2011, 2012, 2013, 2014

2013-11-07

... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice: (13-128)] International Space Station Advisory Committee; Charter Renewal AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of renewal and amendment of the charter of the International Space Station Advisory Committee...

77 FR 51892 - Airworthiness Directives; Honeywell International Inc. Turbofan Engines

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-28

... Airworthiness Directives; Honeywell International Inc. Turbofan Engines AGENCY: Federal Aviation Administration... Honeywell International Inc. models TFE731-4, -4R, -5, -5R, -5AR, and - 5BR series turbofan engines. This AD... International Inc.: (1) Model TFE731-5 series turbofan engines, with a first stage low-pressure turbine (LPT1...

Comprehensive Auditing in Nuclear Medicine Through the International Atomic Energy Agency Quality Management Audits in Nuclear Medicine Program. Part 2: Analysis of Results.

PubMed

Dondi, Maurizio; Torres, Leonel; Marengo, Mario; Massardo, Teresa; Mishani, Eyal; Van Zyl Ellmann, Annare; Solanki, Kishor; Bischof Delaloye, Angelika; Lobato, Enrique Estrada; Miller, Rodolfo Nunez; Ordonez, Felix Barajas; Paez, Diana; Pascual, Thomas

2017-11-01

The International Atomic Energy Agency has developed a program, named Quality Management Audits in Nuclear Medicine (QUANUM), to help its Member States to check the status of their nuclear medicine practices and their adherence to international reference standards, covering all aspects of nuclear medicine, including quality assurance/quality control of instrumentation, radiopharmacy (further subdivided into levels 1, 2, and 3, according to complexity of work), radiation safety, clinical applications, as well as managerial aspects. The QUANUM program is based on both internal and external audits and, with specifically developed Excel spreadsheets, it helps assess the level of conformance (LoC) to those previously defined quality standards. According to their level of implementation, the level of conformance to requested standards; 0 (absent) up to 4 (full conformance). Items scored 0, 1, and 2 are considered non-conformance; items scored 3 and 4 are considered conformance. To assess results of the audit missions performed worldwide over the last 8 years, a retrospective analysis has been run on reports from a total of 42 audit missions in 39 centers, three of which had been re-audited. The analysis of all audit reports has shown an overall LoC of 73.9 ± 8.3% (mean ± standard deviation), ranging between 56.6% and 87.9%. The highest LoC has been found in the area of clinical services (83.7% for imaging and 87.9% for therapy), whereas the lowest levels have been found for Radiopharmacy Level 2 (56.6%); Computer Systems and Data Handling (66.6%); and Evaluation of the Quality Management System (67.6%). Prioritization of non-conformances produced a total of 1687 recommendations in the final audit report. Depending on the impact on safety and daily clinical activities, they were further classified as critical (requiring immediate action; n = 276; 16% of the total); major (requiring action in relatively short time, typically from 3 to 6 months; n = 604

Addressing dual agency: getting specific about the expectations of professionalism.

PubMed

Tilburt, Jon C

2014-01-01

Professionalism requires that physicians uphold the best interests of patients while simultaneously insuring just use of health care resources. Current articulations of these obligations like the American Board of Internal Medicine (ABIM) Foundation's Physician Charter do not reconcile how these obligations fit together when they conflict. This is the problem of dual agency. The most common ways of dealing with dual agency: "bunkering"--physicians act as though societal cost issues are not their problem; "bailing"--physicians assume that they are merely agents of society and deliver care typically based on a strongly consequentialist public health ethic; or "balancing"--a vaguely specified attempt to uphold both patient welfare and societal need for judicious resource use simultaneously--all fail. Here I propose how the problem of dual agency might begin to be addressed with rigor and consistency. Without dealing with the dual agency problem and getting more specific about how to reconcile its norms when they conflict, the expectations of professionalism risk being written off as cute, nonbinding aphorisms from the medical profession.

77 FR 2765 - NASA International Space Station Advisory Committee; Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-19

... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (12-003)] NASA International Space Station Advisory Committee; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of..., the National Aeronautics and Space Administration announces an open meeting of the NASA International...

78 FR 77502 - NASA International Space Station Advisory Committee; Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-23

... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (13-154)] NASA International Space Station Advisory Committee; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of..., the National Aeronautics and Space Administration announces a meeting of the NASA International Space...

77 FR 41203 - NASA International Space Station Advisory Committee; Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-12

... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 12-057] NASA International Space Station Advisory Committee; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of..., the National Aeronautics and Space Administration announces an open meeting of the NASA International...

77 FR 66082 - NASA International Space Station Advisory Committee; Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-01

... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 12-090] NASA International Space Station Advisory Committee; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of..., the National Aeronautics and Space Administration announces an open meeting of the NASA International...

75 FR 51852 - NASA International Space Station Advisory Committee; Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-23

... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice (10-090)] NASA International Space Station Advisory Committee; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of..., the National Aeronautics and Space Administration announces an open meeting of the NASA International...

78 FR 49296 - NASA International Space Station Advisory Committee; Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-13

... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice 13-091] NASA International Space Station Advisory Committee; Meeting AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of..., the National Aeronautics and Space Administration announces a meeting of the NASA International Space...

Methodological approaches in conducting overviews: current state in HTA agencies.

PubMed

Pieper, Dawid; Antoine, Sunya-Lee; Morfeld, Jana-Carina; Mathes, Tim; Eikermann, Michaela

2014-09-01

Overviews search for reviews rather than for primary studies. They might have the potential to support decision making within a shorter time frame by reducing production time. We aimed to summarize available instructions for authors intending to conduct overviews as well as the currently applied methodology of overviews in international Health Technology Assessment (HTA) agencies. We identified 127 HTA agencies and scanned their websites for methodological handbooks as well as published overviews as HTA reports. Additionally, we contacted HTA agencies by e-mail to retrieve possible unidentified handbooks or other related sources. In total, eight HTA agencies providing methodological support were found. Thirteen HTA agencies were found to have produced overviews since 2007, but only six of them published more than four overviews. Overviews were mostly employed in HTA products related to rapid assessment. Additional searches for primary studies published after the last review are often mentioned in order to update results. Although the interest in overviews is rising, little methodological guidance for the conduct of overviews is provided by HTA agencies. Overviews are of special interest in the context of rapid assessments to support policy-making within a short time frame. Therefore, empirical work on overviews needs to be extended. National strategies and experience should be disclosed and discussed. Copyright © 2013 John Wiley & Sons, Ltd.

International sources of financial cooperation for health in developing countries.

PubMed

Howard, L M

1983-01-01

By direct consulation and review of published sources, a study of 16 selected official sources of international financial cooperation was conducted over the August 1979 to August 1980 period in order to assess the policies, programs, and prospects for support of established international health goals. This study demonstrated that approximately 90% of the external health sector funds are provided via development oriented agencies. The major agencies providing such assistance concur that no sector, including health, should be excluded "a priori," providing that the requesting nation conveys its proposals through the appropriate national development planning authority. The agencies in the study also were found to be supporting health related programs in all the geographic regions of the World Health Organization (WHO). An associated review of 30 external funding agencies revealed that only 5 reported providing health assistance in more than half of the countries where they provided assistance for general development purposes. Interviewed sources attributed this to the limited manner in which health proposals have been identified, prepared, and forwarded (with national development authority approval) to international agencies. In 1979 concessional development financing totaled approximately US$29.9 billion, US$24.2 billion being provided by 17 major industrial nations, US$4.7 billion by Organization of Petroleum Exporting (OPEC) countries, and less than US$1 billion by the countries of Eastern Europe. Approximately 2/3 of such concessional financing is administered bilaterally, only 1/3 passing through multilateral institutions. UN agencies receive only 12% of these total concessional development financing resources. In 1979, concessional funding for health totaled approximately US$3 billion, approximately 1/10 of which was administered by WHO and its regional offices. It is anticipated that future international funding for health in developing countries will continue

22 CFR 215.9 - Appeal of initial adverse agency determination.

Code of Federal Regulations, 2010 CFR

2010-04-01

... request for review of such refusal within 60 days after the date of notification of the denial or partial denial. (b) The request for review must be in writing and may be presented in person or by mail to...: Privacy Review Request. Director, Office of External Affairs, Agency for International Development, 2201 C...

International Funding of Educational Development: External Agendas and Internal Adaptations. The Case of Liberia.

ERIC Educational Resources Information Center

Nagel, Joane; Snyder, Conrad W., Jr.

1989-01-01

Explains how international development projects shaped and often distorted organizational aspects of the Liberian education system from 1972 to 1985. Examines the fragmenting effects of policy conflicts among and within development agencies, of the typical structure of educational development projects, and of competition for funds. Contains 42…

76 FR 7114 - International Mail: Mailing Services Price Change

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-09

... POSTAL SERVICE 39 CFR Part 20 International Mail: Mailing Services Price Change AGENCY: Postal... States Postal Service, International Mail Manual (IMM[supreg]) for Mailing Services. This price change correlates to the Postal Service's January 13, 2011 filing of Docket No. R2011-2, Notice of Price Adjustment...

75 FR 9359 - Drawback of Internal Revenue Excise Tax

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-02

... Drawback of Internal Revenue Excise Tax AGENCY: Customs and Border Protection, Department of Homeland... substitution drawback claim for internal revenue excise tax paid on imported merchandise in situations where no excise tax was paid upon the substituted merchandise or where the substituted merchandise is the subject...

76 FR 55799 - Outbound International Mailings of Lithium Batteries

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-09

... equipment with lithium metal or lithium-ion batteries that were to be effective October 3, 2011. These... POSTAL SERVICE 39 CFR Part 20 Outbound International Mailings of Lithium Batteries AGENCY: Postal... would incorporate new maximum limits for the outbound mailing of lithium batteries to international, or...

78 FR 15615 - Reporting Requirements for U.S. Providers of International Telecommunications Services

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-12

...] Reporting Requirements for U.S. Providers of International Telecommunications Services AGENCY: Federal... (Commission) eliminates unnecessary information, streamlines the filing of annual international traffic and... the collection of data on international telecommunications services, the Commission consolidated the...

Training the Future - Interns Harvesting & Testing Plant Experim

NASA Image and Video Library

2017-07-19

In the Space Life Sciences Laboratory at NASA's Kennedy Space Center in Florida, student interns such as Ayla Grandpre are joining agency scientists, contributing in the area of plant growth research for food production in space. Grandpre is majoring in computer science and chemistry at Rocky Mountain College in Billings, Montana. The agency attracts its future workforce through the NASA Internship, Fellowships and Scholarships, or NIFS, Program.

Training the Future - Interns Harvesting & Testing Plant Experim

NASA Image and Video Library

2017-07-19

In the Space Life Sciences Laboratory at NASA's Kennedy Space Center in Florida, student interns such as Payton Barnwell are joining agency scientists, contributing in the area of plant growth research for food production in space. Barnwell is a mechanical engineering and nanotechnology major at Florida Polytechnic University. The agency attracts its future workforce through the NASA Internship, Fellowships and Scholarships, or NIFS, Program.

77 FR 49721 - International Services Surveys and Direct Investment Surveys Reporting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-08-17

...] RIN 0691-AA81 International Services Surveys and Direct Investment Surveys Reporting AGENCY: Bureau of... BEA will follow to collect data on international trade in services and direct investment surveys. The surveys are provided for by the International Investment and Trade in Services Survey Act (the Act) and...

Mandated to fail? Humanitarian agencies and the protection of Palestinian children.

PubMed

Hart, Jason; Forte, Claudia Lo

2013-10-01

This paper considers the efforts of United Nations and international agencies to address the threats to Palestinian children arising from Israeli occupation. It contains an account of the reasons why agencies have failed, over many years, to prevent systematic violations by the Israeli authorities and settlers. The discussion is organised around two inter-related domains: institutional and political. The paper argues that, in the occupied Palestinian territory (oPt), limitations to the ways in which child protection has been conceptualised and pursued in practice are abundantly evident. Nevertheless, political pressure by Western donor governments serves to constrain an approach to child protection that is more preventative in nature, that addresses more explicitly Israeli violations of international law, and that reflects the experience and aspirations of Palestinian children themselves. Ultimately, therefore, the failure to protect Palestinian children must be seen not only as a result of humanitarian miscalculation but also as a consequence of political strategy. © 2013 The Author(s). Disasters © Overseas Development Institute, 2013.

International Space Station (ISS)

NASA Image and Video Library

2000-06-08

Five NASA astronauts and two cosmonauts representing the Russian Aviation and Space Agency take a break in training from their scheduled September 2000 visit to the International Space Station (ISS). Astronauts Terrence W. Wilcutt (right front), and Scott D. Altman (left front) are mission commander and pilot, respectively. On the back row (from the left) are mission specialists Boris V. Morukov, cosmonaut, along with astronauts Richard A. Mastracchio, Edward T. Lu, and Daniel C. Burbank, and cosmonaut Yuri I. Malenchenko. Morukov and Malenchenko represent the Russian Aviation and Space Agency. Launched aboard the Space Shuttle Atlantis on September 8, 2000 at 7:46 a.m. (CDT), the STS-106 crew successfully prepared the International Space Station (ISS) for occupancy. Acting as plumbers, movers, installers and electricians, they installed batteries, power converters, a toilet and a treadmill on the outpost. They also delivered more than 2,993 kilograms (6,600 pounds) of supplies. Lu and Malenchenko performed a space walk to connect power, and data and communications cables to the newly arrived Zvezda Service Module and the Station.

Internal Quality Assurance Benchmarking. ENQA Workshop Report 20

ERIC Educational Resources Information Center

Blackstock, Douglas; Burquel, Nadine; Comet, Nuria; Kajaste, Matti; dos Santos, Sergio Machado; Marcos, Sandra; Moser, Marion; Ponds, Henri; Scheuthle, Harald; Sixto, Luis Carlos Velon

2012-01-01

The Internal Quality Assurance group of ENQA (IQA Group) has been organising a yearly seminar for its members since 2007. The main objective is to share experiences concerning the internal quality assurance of work processes in the participating agencies. The overarching theme of the 2011 seminar was how to use benchmarking as a tool for…

International Cooperation in the Field of International Space Station (ISS) Payload Safety

NASA Technical Reports Server (NTRS)

Heimann, Timothy; Larsen, Axel M.; Rose, Summer; Sgobba, Tommaso

2005-01-01

In the frame of the International Space Station (ISS) Program cooperation, in 1998, the European Space Agency (ESA) approached the National Aeronautics and Space Administration (NASA) with the unique concept of a Payload Safety Review Panel (PSRP) "franchise" based at the European Space Technology Center (ESTEC), where the panel would be capable of autonomously reviewing flight hardware for safety. This paper will recount the course of an ambitious idea as it progressed into a fully functional reality. It will show how a panel initially conceived at NASA to serve a national programme has evolved into an international safety cooperation asset. The PSRP established at NASA began reviewing ISS payloads approximately in late 1994 or early 1995 as an expansion of the pre-existing Shuttle Program PSRP. This paper briefly describes the fundamental Shuttle safety process and the establishment of the safety requirements for payloads intending to use the Space Transportation System and International Space Station (ISS). The paper will also offer some historical statistics about the experiments that completed the payload safety process for Shuttle and ISS. The paper 1 then presents the background of ISS agreements and international treaties that had to be taken into account when establishing the ESA PSRP. The detailed franchising model will be expounded upon, followed by an outline of the cooperation charter approved by the NASA Associate Administrator, Office of Space Flight, and ESA Director of Manned Spaceflight and Microgravity. The resulting ESA PSRP implementation and its success statistics to date will then be addressed. Additionally the paper presents the ongoing developments with the Japan Aerospace Exploration Agency. The discussion will conclude with ideas for future developments, such to achieve a fully integrated international system of payload safety panels for ISS.

The psychological consequences of the Chernobyl accident--findings from the International Atomic Energy Agency Study.

PubMed Central

Ginzburg, H M

1993-01-01

In October 1989, more than 3 years after the nuclear power plant accident at Chernobyl, in the Ukraine, the Government of the Union of Soviet Socialist Republics requested that the International Atomic Energy Agency (IAEA) evaluate the medical and psychological health of residents living in areas identified as being contaminated with radioactive fallout. The IAEA designed and conducted a collaborative study to examine whether there were any measurable effects of exposure to the low levels of ionizing radiation resulting from the accident. The study, using structured interviews and IAEA laboratory equipment, collected data on more than 1,350 residents of 13 villages. IAEA clinical staff members concluded that they could not identify any health disorders in either the contaminated or nearby (uncontaminated) control villages that could be attributed directly to radiation exposure. The clinical staff, however, did note that the levels of anxiety and stress of the villagers appeared to be disproportionate to the biological significance of the levels of IAEA-measured radio-active contamination. Almost half the adults in all the villages were unsure if they had a radiation-related illness. More than 70 percent of persons in the contaminated villages wanted to move away, and approximately 83 percent believed that the government should relocate them. The IAEA effort indicates that the villagers need to be educated about their actual risks, and they need to understand what types of illnesses are, and are not, associated with exposure to radioactive contamination. Unfortunately, the villagers' needs may exceed the available resources of their local and central governments. PMID:8464974