48 CFR 1052.234-71 - Notice of Earned Value Management System-Post-Award IBR (Core) AUG 2011

Code of Federal Regulations, 2012 CFR

2012-10-01

... Management System-Post-Award IBR (Core) AUG 2011 1052.234-71 Section 1052.234-71 Federal Acquisition... Texts of Provisions and Clauses 1052.234-71 Notice of Earned Value Management System—Post-Award IBR... require the contractor to use an earned value management system (EVMS) and for which the Government...

48 CFR 1052.234-70 - Notice of Earned Value Management System-Pre-Award IBR (Core) AUG 2011

Code of Federal Regulations, 2014 CFR

2014-10-01

... Management System-Pre-Award IBR (Core) AUG 2011 1052.234-70 Section 1052.234-70 Federal Acquisition... Texts of Provisions and Clauses 1052.234-70 Notice of Earned Value Management System—Pre-Award IBR (Core... require the Contractor to use an earned value management system (EVMS) and for which the Government...

48 CFR 1052.234-70 - Notice of Earned Value Management System-Pre-Award IBR (Core) AUG 2011

Code of Federal Regulations, 2012 CFR

2012-10-01

... Management System-Pre-Award IBR (Core) AUG 2011 1052.234-70 Section 1052.234-70 Federal Acquisition... Texts of Provisions and Clauses 1052.234-70 Notice of Earned Value Management System—Pre-Award IBR (Core... require the Contractor to use an earned value management system (EVMS) and for which the Government...

48 CFR 1052.234-71 - Notice of Earned Value Management System-Post-Award IBR (Core) AUG 2011

Code of Federal Regulations, 2013 CFR

2013-10-01

... Management System-Post-Award IBR (Core) AUG 2011 1052.234-71 Section 1052.234-71 Federal Acquisition... Texts of Provisions and Clauses 1052.234-71 Notice of Earned Value Management System—Post-Award IBR... require the contractor to use an earned value management system (EVMS) and for which the Government...

48 CFR 1052.234-71 - Notice of Earned Value Management System-Post-Award IBR (Core) AUG 2011

Code of Federal Regulations, 2014 CFR

2014-10-01

... Management System-Post-Award IBR (Core) AUG 2011 1052.234-71 Section 1052.234-71 Federal Acquisition... Texts of Provisions and Clauses 1052.234-71 Notice of Earned Value Management System—Post-Award IBR... require the contractor to use an earned value management system (EVMS) and for which the Government...

48 CFR 1052.234-70 - Notice of Earned Value Management System-Pre-Award IBR (Core) AUG 2011

Code of Federal Regulations, 2013 CFR

2013-10-01

... Management System-Pre-Award IBR (Core) AUG 2011 1052.234-70 Section 1052.234-70 Federal Acquisition... Texts of Provisions and Clauses 1052.234-70 Notice of Earned Value Management System—Pre-Award IBR (Core... require the Contractor to use an earned value management system (EVMS) and for which the Government...

48 CFR 1052.234-71 - Notice of Earned Value Management System-Post-Award IBR (Core) AUG 2011

Code of Federal Regulations, 2011 CFR

2011-10-01

... Management System-Post-Award IBR (Core) AUG 2011 1052.234-71 Section 1052.234-71 Federal Acquisition... Texts of Provisions and Clauses 1052.234-71 Notice of Earned Value Management System—Post-Award IBR... require the contractor to use an earned value management system (EVMS) and for which the Government...

48 CFR 1052.234-70 - Notice of Earned Value Management System-Pre-Award IBR (Core) AUG 2011

Code of Federal Regulations, 2011 CFR

2011-10-01

... Management System-Pre-Award IBR (Core) AUG 2011 1052.234-70 Section 1052.234-70 Federal Acquisition... Texts of Provisions and Clauses 1052.234-70 Notice of Earned Value Management System—Pre-Award IBR (Core... require the Contractor to use an earned value management system (EVMS) and for which the Government...

Asymmetric reduction of benzil to (S)-benzoin with Penicillium claviforme IAM 7294 in a liquid-liquid interface bioreactor (L-L IBR).

PubMed

Oda, Shinobu; Isshiki, Kunio

2008-05-01

The asymmetric reduction of benzyl to (S)-benzoin with Penicillium claviforme IAM 7294 was applied to a liquid-liquid interface bioreactor (L-L IBR) using a unique polymeric material, ballooned microsphere (MS). The L-L IBR showed superior performance, as compared with suspension, organic-aqueous two-liquid-phase, and solid-liquid interface bioreactor (S-L IBR) systems, affording 14.4 g/l-organic phase of (S)-benzoin (99.0% ee).

Estudio de distintos modelos de protuberancias solares

NASA Astrophysics Data System (ADS)

Cirigliano, D.; Rovira, M.; Mauas, P.

En este trabajo presentamos perfiles de líneas del CaII, MgII y HeI calculados para distintos modelos de protuberancias, y los comparamos con observaciones obtenidas por los satélites OSO 8 y SOHO. Para obtener las poblaciones de los distintos niveles de los átomos, utilizamos un código numérico que combina las ecuaciones de transporte de radiación y equilibrio estadístico en un único sistema de ecuaciones no lineal. Los modelos básicos que consideramos para las protuberancias consisten en placas homogéneas y unidimensionales apoyadas sobre la superficie del Sol. Dichas placas se hallan estratificadas en hebras y los modelos difieren entre sí en la temperatura y ancho de la placa, en la presión a la cual se halla el plasma y en el número de hebras. A partir de estos modelos se investiga cada uno de estos parámetros libres y como influyen en la atmósfera de las protuberancias solares y en el perfil de línea de cada especie estudiada, con el objetivo de determinar las condiciones en las que se halla el material atmosférico de estas protuberancias.

Análise da aplicação e dos resultados do modelo OPM3® para a área da saúde

PubMed Central

Augusto dos Santos, Luis; de Fátima Marin, Heimar

2015-01-01

Esta pesquisa procurou analisar se um modelo de questionário criado por uma comunidade internacional de gerenciamento de projetos e se é aplicavél a organizações voltadas a área de saúde. O modelo OPM3® (Organizational Project Management Maturity Model) foi criado para que organizações de qualquer área ou porte pudessem identificar a presença, ou ausência, de boas práticas de gerenciamento. O objetivo da aplicação desse modelo é avaliar sempre a organização e não o entrevistado. No presente artigo, são apresentados os resultados da aplicação desse modelo em uma organização que possuía produtos e serviços de tecnologia da informação aplicados à área de saúde. Este estudo verificou que o modelo é aplicável de forma rápida e que a organização analisada possuía um número expressivo de boas práticas. PMID:26924862

National surveillance plan for infectious bovine rhinotracheitis (IBR) in autochthonous Italian cattle breeds: Results of first year of activity.

PubMed

Maresca, Carmen; Scoccia, Eleonora; Dettori, Annalisa; Felici, Andrea; Guarcini, Roberta; Petrini, Stefano; Quaglia, Andrea; Filippini, Giovanni

2018-06-01

Infectious bovine rhinotracheitis (IBR)/infectious pustular vulvovaginitis (IPV) caused by Bovine alphaherpesvirus 1 (BoHV-1) is a significant disease in domestic and wild cattle. In June 2015, the Ministry of Agriculture, Food and Forestry in Italy approved a national surveillance plan to control and eradicate IBR in beef cattle breeds. The objective of this study was to evaluate the results of the first year of the IBR voluntary surveillance plan in Italy. The aim of the plan is to eradicate IBR in all bovines recorded in the National Herd Book for Italian beef cattle breeds over six years. Monetary incentives are used to encourage breeders to achieve the annual seroprevalence ranges stated in the plan. A Ministerial decree states that all bovines in breeding herds and aged older than 12 months should be serologically tested. Serum samples were tested for presence of the antibody to glycoprotein E of BoHV-1 using commercially available enzyme-linked immunosorbent assays. The national herd seroprevalence was 55.49% (95% confidence interval [CI] 52.01-58.92). Of 25,121 bovines tested for antibodies against BoHV-1, 8014 were positive. The seroprevalence in animals from autochthonous Italian cattle breeds was 31.89% (95% CI 31.31-32.47). Seroprevalence was highest in Podolica cattle (55.14%; 95% CI 54.07-56.21), lowest in Maremmana cattle (9.95%; 95% CI 7.99-12.31), and intermediate in Chianina (22.01%; 95% CI 21.03-23.01), Marchigiana (24.85%; 95% CI 23.52-26.23), and Romagnola (15.60%; 95% CI 14.62-16.64) cattle. These seroprevalence rates indicate a need for intervention to decrease the inevitable severe economic losses arising from BoHV-1 infection. Although some regions in Italy have a long history of combatting BoHV-1 infection, only the province of Bolzano has eradicated IBR. Copyright © 2018 Elsevier B.V. All rights reserved.

Uso de modelos mecânicos em curso informal de astronomia para deficientes visuais. Resgate de uma experiência

NASA Astrophysics Data System (ADS)

Tavares, E. T., Jr.; Klafke, J. C.

2003-08-01

O presente trabalho propõe-se a resgatar uma experiência que teve lugar no Planetário de São Paulo nos anos 60. Em 1962, o Sr. Acácio, então com 37 anos, deficiente visual desde os 27, passou a assistir às aulas ministradas pelo Prof. Aristóteles Orsini aos integrantes do corpo de servidores do Planetário. O Sr. Acácio era o único deficiente da turma e, embora possuísse conhecimentos básicos e relativamente avançados de matemática, enfrentava dificuldades na compreensão e acompanhamento da exposição, como também em estudos posteriores. Com o intuito de auxiliá-lo na superação desses problemas, o Prof. Orsini solicitou a construção de modelos mecânicos que, através do sentido do tato, permitissem o acompanhamento das aulas e a transposição do modelo para o "constructo" mental. Essa prática mostrou-se tão eficaz que facilitou sobejamente o aprendizado da matéria pelo sujeito. O Sr. Acácio passou a integrar o corpo de professores do Planetário/Escola Municipal de Astrofísica, tendo ficado responsável pelo curso de "Introdução à Astronomia" por vários anos. Além disso, a experiência foi tão bem sucedida que alguns dos modelos tiveram seus elementos constitutivos pintados diferencialmente para serem utilizados em cursos regulares do Planetário, tornando-se parte integrante do conjunto de recursos didáticos da instituição. É pensando nessa eficácia, tanto em seu objetivo original permitir o aprendizado de um deficiente visual quanto no subsidiário recurso didático sistemático da instituição que decidimos resgatar essa experiência. Estribados nela, acreditamos ser extremamente produtivo, em termos educacionais, o aperfeiçoamento dos modelos originais, agora resgatados e restaurados, e a criação de outros que pudessem ser utilizados no ensino dessa ciência a deficientes visuais.

Discos de acreción circumplanares: Modelo de Co-acreción

NASA Astrophysics Data System (ADS)

Parisi, M. G.; de Elía, G.

Los discos de acreción circumplanetarios precursores de los satélites regulares de los planetas gigantes, se pueden formar por cuatro mecanismos (Pollack y otros, 1991, In Uranus, Bergtralh, Miner y Mattews, Eds., p. 469, Univ. de Arizona Press, Tucson). En este trabajo estudiamos uno de tales mecanismos: el Modelo de Co-acreción. En dicho modelo, el disco circumplanetario se forma a partir de las colisiones mutuas entre planetesimales dentro de la esfera de Hill del planeta durante el proceso de formación planetaria. Realizamos un modelo semi-analítico para calcular la masa del disco y compararla con la masa requerida para formar los satélites regulares de los planetas gigantes. Hemos obtenido una cota superior para la masa del disco que resulta inferior a la masa de los satélites más grandes de los planetas gigantes. En principio, estos resultados permitirían descartar el modelo de co-acreción como uno de los procesos que podrían dar lugar a la formación de los satélites regulares. Estos resultados permiten obtener restricciones en el escenario de formación planetaria y en los mecanismos de formación de sistemas de satélites.

Construyendo modelos confiables de estrellas rías

NASA Astrophysics Data System (ADS)

Mauas, P. J.; Falchi, A.

Se estudian las aproximaciones que se realizan usualmente al calcular modelos de estrellas frías (redistribución completa para la lí nea Lyman-α, despreciar el ``line-blanketing", suponer los metales en LTE), y cómo influyen en los distintos observables. Asimismo, se evalúa cuál es la información que cada observable nos da sobre la atmósfera de la estrella, y cuáles son las incertidumbres de cada modelo.

Comparação de modelos para o cálculo de perturbações orbitais devidas à maré terrestre

NASA Astrophysics Data System (ADS)

Vieira Pinto, J.; Vilhena de Moraes, R.

2003-08-01

Aplicações recentes de satélites artificiais com finalidades geodinâmicas requerem órbitas determinadas com bastante precisão. Em particular marés terrestres influenciam o potencial terrestre causando perturbações adicionais no movimento de satélites artificiais, as quais tem sido medidas por diversos processos. A atração exercida pela lua e pelo sol sobre a terra produz deslocamentos elásticos em seu interior e uma protuberância em sua superfície. O resultado é uma pequena variação na distribuição da massa na terra, consequentemente no geopotencial. As perturbações nos elementos orbitais de satélites artificiais terrestres devidas a maré terrestre podem ser estudadas a partir das equações de Lagrange, considerando-se um conveniente potencial. Por outro lado, como tem sido feito pelo IERS, as mudanças induzidas pela maré terrestre no geopotencial podem ser convenientemente modeladas como variações nos coeficientes Cnm e Snm do geopotencial. As duas teorias ainda não foram comparados para um mesmo satélite. Neste trabalho são apresentadas e comparadas as variações de longo período e seculares nas perturbações orbitais devidas à maré terrestre, calculadas por um modelo simples, o de Kozai, e pelo modelo do IERS. Resultados preliminares mostram, para os satélites SCD2 e CBERS1, e para a Lua em movimento elíptico e precessionando, as perturbações seculares no argumento do perigeu e na longitude do nodo ascendente.

Espectro de radiación derivado de un modelo de colapso protoestelar

NASA Astrophysics Data System (ADS)

Coca, S.; Rohrmann, R.

El exceso de emisión infrarroja en objetos protoestelares es atribuido usualmente a un disco de material en torno al cuerpo central. A pesar del avance alcanzado en la elaboración de modelos, aún existen dificultades para explicar la ley de temperatura del disco necesaria para reproducir las luminosidades y perfiles de energía observados. Nuestra propuesta consiste en determinar la distribución espectral de la radiación derivada de un particular modelo de colapso protoestelar, y estudiar la evolución del espectro desde estadíos tempranos de la contracción gravitatoria. Este plan es orientado a evaluar las propiedades del modelo (distribuciones de masa y temperatura del material circunestelar) por comparación con datos observacionales, a fin de inferir de ello los posibles ajustes requeridos en la teoría actualmente empleada.

Modelo analítico del efecto de PRS sobre satélites GPS

NASA Astrophysics Data System (ADS)

Meza, A.; Brunini, C.; Usandivaras, J. C.

El sistema GPS (Global Position System) es, hoy en día, la herramienta de navegación y posicionamiento más potente y lo será sin duda en la próxima década. Gran parte de su valiosa utilidad se debe a la alta precisión que permite lograr y ésta, a su vez, depende, entre otras causas, de la precisión con que se conocen las órbitas de los satélites. La presión de radiación solar (PRS) fija el límite de la precisión con que pueden calcularse en la actualidad las efemérides satelitarias. El objetivo de este trabajo es proponer una mejor resolución de este fenómeno. El modelo analítico aquí presentado, se basa en el análisis del comportamiento de los residuos de un ajuste por mínimos cuadrados en el que se utiliza el modelo de PRS propuesto por Beutler. El mismo consiste en un modelo determinista del fenómeno con dos parámetros libres. Los resultados obtenidos ponen de manifiesto que, aún después de aplicar dichos parámetros, prevalecen en los residuos efectos semidiurnos en las componentes radial,tangencial y normal. Estos resultados obtenidos se comparan con los de un trabajo desarrollado por el Instituto de Berne (Beutler et al., 1994), en el que se utilizaron como pseudo-observaciones las órbitas precisas del IGS (CODE). El intervalo de integración escogido por este centro fueron las semanas 680 y 681. En resumen se tienen arcos de 14 días para todos los satélites, donde las efemérides precisas de los mismos para los 14 días fueron utilizados como pseudo-observaciones. El modelo de fuerza que empleó dicho centro fue básicamente el tradicional en lo que respecta al modelo de las fuerzas gravitacionales, y para la PRS utilizo el modelo standard de Beutler. Los parámetros de este modelo junto con las 6 condiciones iniciales (posición y velocidad) fueron ajustados por el método general de mínimos cuadrados. Los residuos en la componente radial, tangencial y normal, para los satélites con un buen comportamiento, presentan una

Application of Three-Dimensional Models for the Teaching of Time Zones. (Breton Title: Aplicação de Modelos Tridimensionais Para o Ensino de Fusos Horários.) Aplicación de Modelos Tridimensionales Para la Enseñanza de Husos Horarios

NASA Astrophysics Data System (ADS)

Azevedo Sobreira, Paulo Henrique

2012-07-01

There are several interesting astronomical topics that must be addressed in the High School and Elementary/Middle School in the disciplines of Geography and of Sciences. Among them, the topic of time zones which is one of the most important to understand the correlation of the Earth's rotation and its implications on daily activities of citizens in local scale, regional and global scales which involve problems of time differences. For the teaching of time zones in the lessons of Geography, for example, there are bi-dimensional representations of thematic maps of world time zones, textbooks and atlas. It happens that teachers face some difficulties to permit its students to view three-dimensionally this astronomical phenomenon from the textbooks available in schools. The aim of this paper is to present two proposals with low-cost materials, which allow the preparation of three-dimensional models for the teaching of time zones. Há vários temas astronômicos interessantes que devem ser trabalhados nos Ensinos Médio e Fundamental, nas disciplinas de Geografia e de Ciências. Entre eles, o tema dos fusos horários que é um dos mais importantes para se correlacionar a rotação da Terra e suas implicações nas atividades cotidianas dos cidadãos em escala local, regional e global, que envolvem problemas de diferenças horárias. Para o ensino dos fusos horários nas aulas de Geografia, por exemplo, há representações bidimensionais de mapas temáticos de fusos horários mundiais, nos livros didáticos e nos atlas. Ocorre que os professores enfrentam algumas dificuldades para possibilitar aos seus alunos a visão tridimensional deste fenômeno astronômico, a partir dos materiais didáticos disponíveis nas escolas. O objetivo deste trabalho é apresentar duas propostas para a confecção de materiais de baixo custo, que possibilitem a elaboração de modelos tridimensionais para o ensino dos fusos horários. Hay algunos temas astronómicos interesantes que se

Methane production from cattle manure supplemented with crude glycerin from the biodiesel industry in CSTR and IBR.

PubMed

Castrillón, L; Fernández-Nava, Y; Ormaechea, P; Marañón, E

2013-01-01

The aim of the present research work was to optimise biogas production from cattle manure by adding crude glycerin from the biodiesel industry. For this purpose, 6%v/v crude glycerin (the optimum amount according to previous research) was added to ground manure and the mixture was sonicated to enhance biodegradability prior to anaerobic co-digestion at 55 °C. Two different reactors were used: continuously stirred (CSTR) and induced bed (IBR). The methanol and pure glycerin contents of the crude glycerin used in this study were 5.6% and 49.4% (w/w), respectively. The best results when operating in CSTR were obtained for an organic loading rate (OLR) of 5.4 kg COD/m(3) day, obtaining 53.2m(3) biogas/t wet waste and 80.7% COD removal. When operating in IBR, the best results were obtained for an OLR of 6.44 kg COD/m(3)day, obtaining 89.6% COD removal and a biogas production of 56.5m(3)/t wet waste. Copyright © 2012 Elsevier Ltd. All rights reserved.

Uso Del Condón en Adolescentes Nahuas, un Modelo Explicativo.

PubMed

Tirado, María de Los Ángeles Meneses; Benavides-Torres, Raquel A; Navarro, Sergio Meneses; de la Colina, Juan Antonio Doncel; Rodríguez, Dora Julia Onofre; Hernández, Francisco Javier Baéz

2018-03-01

En México, la población indígena supera los siete millones de habitantes, en Puebla el grupo más representativo es el Náhuatl. Sin embargo, las condiciones de vida, salud, educación y transporte son precarias para esta población. En los adolescentes, las responsabilidades como el matrimonio, la familia y los compromisos ante la comunidad, favorecen conductas de riesgo sexual que dificultan su desarrollo económico, social y reproductivo. El objetivo fue proponer un modelo explicativo del uso del condón en adolescentes nahuas. Método. Bajo el marco de la teoría social cognitiva, el concepto de valores culturales de Leininger y el proceso de la sustracción teórica, se desarrolló este artículo. Se muestran las relaciones del modelo con las proposiciones y los factores que influyen en el uso del condón para este grupo específico. Finalmente, el modelo explica las variables de interés, los niveles de abstracción y las relaciones entre sí en el contexto náhuatl. El siguiente paso será implementar los indicadores empíricos para conocer el grado de influencia de los factores personales y ambientales hacia el uso del condón en adolescentes nahuas. Resultados que aportarán información para el desarrollo del conocimiento en enfermería y la reducción de riesgo sexual de esta población.

Desenvolvimento de modelo clínico para predição da possibilidade de identificação da artéria de Adamkiewicz por angiotomografia

PubMed Central

Amato, Alexandre Campos Moraes; Parga, José Rodrigues; Stolf, Noedir Antônio Groppo

2018-01-01

Resumo Contexto Diferenças morfológicas da artéria de Adamkiewicz (AKA) entre a população portadora e não portadora de doença aórtica têm importância clínica, influenciando as complicações neuroisquêmicas da medula espinhal em procedimentos operatórios. Ainda não é conhecida a correlação entre parâmetros clínicos e a previsibilidade da identificação dessa artéria pela angiotomografia. Objetivo Desenvolver um modelo matemático que, através de parâmetros clínicos correlacionados com aterosclerose, possa prever a probabilidade de identificação da AKA em pacientes submetidos a angiotomografias. Método Estudo observacional transversal utilizando banco de imagens e dados de pacientes. Foi feita análise estatística multivariada e criado modelo matemático logit de predição para identificação da AKA. Variáveis significativas foram utilizadas na montagem da fórmula para cálculo da probabilidade de identificação. O modelo foi calibrado, e a discriminação foi avaliada pela curva receiver operating characteristic (ROC). A seleção das variáveis explanatórias foi guiada pela maior área na curva ROC (p = 0,041) e pela significância combinada das variáveis. Resultados Foram avaliados 110 casos (54,5% do sexo masculino, com idade média de 60,97 anos e etnia com coeficiente B -2,471, M -1,297, N -0,971), com AKA identificada em 60,9%. Índice de massa corporal: 27,06 ± 0,98 (coef. -0,101); fumantes: 55,5% (coef. -1,614/-1,439); diabéticos: 13,6%; hipertensos: 65,5% (coef. -1,469); dislipidêmicos: 58,2%; aneurisma aórtico: 38,2%; dissecção aórtica: 12,7%; e trombo mural: 24,5%. Constante de 6,262. Fórmula para cálculo da probabilidade de detecção: (e−(Coef. Etnia+(Coef. IMC×IMC)+Coef.fumante+Coef.HAS+Coef.dislip+Constante)+1)−1 . O modelo de predição foi criado e disponibilizado no link https://vascular.pro/aka-model . Conclusão Com as covariáveis etnia, índice de massa corporal, tabagismo, hipertens

Concepciones Alternativas de "Fotosintesis" en estudiantes Universitarios del curso basico de Biologia y posibles correcciones con el Modelo Educativo MODEF

NASA Astrophysics Data System (ADS)

De Jesus Roman, Sandra

Concepciones Alternativas de Fotosíntesis en estudiantes Universitariosdel curso básico de Biología y posibles correcciones con el Modelo Educativo MODEF El modelo educativo para la enseñanza de Fotosíntesis (MODEF) se implantó para trabajar el problema de las concepciones alternativas (CA) en un curso de Biología General. Se evaluaron los resultados en cuanto al logro del aprendizaje significativo. La pregunta central de la investigación fue: ¿Cómo aporta el modelo educativo en la didáctica y comprensión del tema de fotosíntesis? Se efectuó una investigación acción con una fase cuantitativa y una cualitativa. Para la fase cuantitativa se elaboró una prueba para determinar las concepciones alternativas, se validó y se sometió a los estudiantes que participaron en el estudio antes y después de ofrecer la unidad de metabolismo celular. Los participantes eran estudiantes de primer año de la Universidad de Puerto Rico en Bayamón (UPRB). Se llevó a cabo un análisis de consistencia interna de la prueba mediante el método Alfa de Cronbach. Se analizaron las contestaciones a cada pregunta mediante la prueba de Ji cuadrado de contingencia, se efectuó la prueba de t y el coeficiente r de Pearson. La fase cualitativa incluyó la observación participativa de la investigadora- profesora, las reflexiones de los estudiantes y la información de las entrevistas semi-estructuradas que se realizaron a tres estudiantes del curso. El análisis se llevó a cabo mediante el Modelo de Wolcott. Se trabajaron diez CA de las cuales siete fueron corregidas mediante el Modelo MODEF. Las actividades más importantes para el proceso de aprendizaje incluyeron el trabajo de investigación o búsqueda de información para hacer una presentación digital, la elaboración de tablas, los mapas de conceptos, el uso de visuales o videos y las analogías para explicar conceptos o procesos. En conclusión: se recomienda el uso del Modelo MODEF para la discusión del tema de

Solazyme Integrated Biorefinery (SzIBR): Diesel Fuels from Heterotrophic Algae

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brinkmann, David

2014-12-23

Under Department of Energy Award Number DE-EE0002877 (the “DOE Award”), Solazyme, Inc. (“Solazyme”) has built a demonstration scale “Solazyme Integrated Biorefinery (SzlBR).” The SzIBR was built to provide integrated scale-up of Solazyme’s novel heterotrophic algal oil biomanufacturing process, validate the projected commercial-scale economics of producing multiple algal oils, and to enable Solazyme to collect the data necessary to complete the design of its first commercial-scale facility. Solazyme’s technology enables it to convert a range of low-cost plant-based sugars into high-value oils. Solazyme’s renewable products replace or enhance oils derived from the world’s three existing sources—petroleum, plants, and animal fats. Solazymemore » tailors the composition of its oils to address specific customer requirements, offering superior performance characteristics and value. This report summarizes history and the results of the project.« less

Studies of electrochemical interfaces by TOF neutron reflectometry at the IBR-2 reactor

NASA Astrophysics Data System (ADS)

Petrenko, V. I.; Gapon, I. V.; Rulev, A. A.; Ushakova, E. E.; Kataev, E. Yu; Yashina, L. V.; Itkis, D. M.; Avdeev, M. V.

2018-03-01

The operation performance of electrochemical energy conversion and storage systems such as supercapacitors and batteries depends on the processes occurring at the electrochemical interfaces, where charge separation and chemical reactions occur. Here, we report about the tests of the neutron reflectometry cells specially designed for operando studies of structural changes at the electrochemical interfaces between solid electrodes and liquid electrolytes. The cells are compatible with anhydrous electrolytes with organic solvents, which are employed today in all lithium ion batteries and most supercapacitors. The sensitivity of neutron reflectometry applied at the time-of-flight (TOF) reflectometer at the pulsed reactor IBR-2 is discussed regarding the effect of solid electrolyte interphase (SEI) formation on metal electrode surface.

Spectrum and density of neutron flux in the irradiation beam line no. 3 of the IBR-2 reactor

NASA Astrophysics Data System (ADS)

Shabalin, E. P.; Verkhoglyadov, A. E.; Bulavin, M. V.; Rogov, A. D.; Kulagin, E. N.; Kulikov, S. A.

2015-03-01

Methodology and results of measuring the differential density of the neutron flux in irradiation beam line no. 3 of the IBR-2 reactor using neutron activation analysis (NAA) are presented in the paper. The results are compared to the calculation performed on the basis of the 3D MCNP model. The data that are obtained are required to determine the integrated radiation dose of the studied samples at various distances from the reactor.

Modelo de accesibilidad de conceptos matematicos aplicados en el curso de Astronomia Descriptiva para estudiantes con impedimentos visuales en la UPR

NASA Astrophysics Data System (ADS)

Isidro Villamizar, Gloria Maria

Este estudio utiliza metodologia de investigacion cualitativa, con el proposito de describir, analizar y evaluar los procesos de diseno y desarrollo de un modelo de accesibilidad que consiste en estrategias de ensenanza de las matematicas para estudiantes con impedimentos visuales matriculados en el curso de Astronomia Descriptiva en la UPR. Se utilizaron las siguientes estrategias para recopilar la informacion, 1) reflexiones de la investigadora en el proceso de diseno y desarrollo de las lecciones adaptadas, que se registraron en un diario reflexivo. 2) entrevista semiestructurada luego de haber trabajado las lecciones de aprendizaje adaptadas con los participantes. 3) observaciones y notas de la investigadora del trabajo de los participantes. Para obtener la informacion de los participantes se obtuvo los permisos institucionales necesarios; se seleccionaron los participantes y se validaron los instrumentos; se realizo el desarrollo de las lecciones adaptadas con los participantes; y finalmente, se analizo la informacion obtenida. El diseno de las lecciones de aprendizaje adaptadas se hizo siguiendo las recomendaciones curriculares de los temas de matematicas aplicados en el curso de Astronomia Descriptiva realizado por la investigadora durante su semestre de internado. El testimonio de las voces de los participantes se obtuvo del proceso de desarrollo de las lecciones de aprendizaje adaptadas de temas seleccionados de conceptos matematicos requeridos en el curso de Astronomia Descriptiva y de la entrevista semiestructurada con los participantes, luego de haber trabajado las lecciones de aprendizaje. Para el desarrollo de las lecciones de aprendizaje, se utilizaron materiales tactiles adaptados, materiales tactiles disenados y materiales disponibles comercialmente. Los textos de las lecciones se imprimieron en tinta y en Braille. Se exhorta a disenar y desarrollar estrategias de ensenanza accesibles, considerando como recursos para evaluar su efectividad a

Melhoramentos no código Wilson-Devinney para binárias eclipsantes

NASA Astrophysics Data System (ADS)

Vieira, L. A.; Vaz, L. P. R.

2003-08-01

A análise de curvas de luz e velocidades radiais de sistemas binários eclipsantes pode ser feita por meio de vários modelos. Um desses é o Modelo Wilson-Devinney (WD). Ao longo dos anos, esse modelo sofreu várias alterações em seus códigos principais, com a finalidade de torná-lo mais consistente tanto fíisica como numericamente. O Modelo WD tem sido melhorado de várias maneiras em seus dois códigos: um para a predição das curvas de luz teórica e de velocidade radiais e outra para as soluções destas curvas. Teoricamente, na física do modelo, nós introduzimos a possibilidade de levar em conta os efeitos do movimento apsidal. Numericamente, nós introduzimos a possibilidade de usar o Método SIMPLEX no procedimento da solução, como uma alternativa para o já implementado Método de Mínimos Quadrados (Least Squares Method). Estas modificações, juntamente com outras já introduzidas pelo nosso grupo anteriormente, tornam o código mais eficiente na solução das curvas de luz e de velocidade radiais de binárias eclipsantes. Como o modelo tem sido usado para analisar sistemas com componentes pré-sequência principal (TY CrA, Casey et al. 1998, Vaz et al. 1998), SM 790, Stassun et al. 2003), este melhoramento beneficiará estes casos também. Apresentamos os resultados obtidos com a modificação do código WD por meio do uso de dados da estrela GL Carinae, comprovando, (1) que os parâmetros orbitais calculados por nós são coerentes com os obtidos anteriormente na literatura (Giménez & Clausen, 1986) e com os obtidos por Faria (1987), e (2) que a implementação do Método SIMPLEX torna o código mais lento mas completamente consistente internamente e evita os problemas gerados pelo uso do Método de Mínimos Quadrados, tais como imprecisão no cálculo das derivadas parciais e convergência para mínimos locais.

Difusión de Arnold en un modelo simple

NASA Astrophysics Data System (ADS)

Cincotta, P. M.; Nuñez, J. A.; Miloni, O.

Investigadores como Merritt, Valluri, Pfenniger o Contopoulos (por citar los más relevantes) consideran seriamente la hipótesis que la difusión de Arnold juega un rol importante en la evolución dinámica de los sistemas estelares y planetarios. Sin embargo no existe ninguna evidencia. El mayor problema para investigar fenómenos como éste es que uno debe estudiar numéricamente sistemas multidimensionales (más de dos grados de libertad) y visualizar de alguna manera el espacio de fases (más de cuatro dimensiones). Más complicado aún es el caso de difusión de Arnold, donde deben considerarse tiempos de movimiento extremadamente largos y tratar con parámetros exponencialmente pequeños. El propósito de este trabajo es estudiar, en un modelo simple 3D, la existencia o no de difusión de Arnold mediante experimentos numéricos y estimaciones analíticas. Siguiendo los trabajos de Cincotta (2000) y Cincotta, Nuñez y Simo (2000), aquí se pretende ``visualizar" la difusión y, a la vez, determinar la escala de tiempo en la que ésta se podría manifestar. Este trabajo es el escalón inicial para luego abordar este problema en modelos.

The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension

PubMed Central

Smit, Judith J; Monteferrario, Davide; Noordermeer, Sylvie M; van Dijk, Willem J; van der Reijden, Bert A; Sixma, Titia K

2012-01-01

Activation of the NF-κB pathway requires the formation of Met1-linked ‘linear' ubiquitin chains on NEMO, which is catalysed by the Linear Ubiquitin Chain Assembly Complex (LUBAC) E3 consisting of HOIP, HOIL-1L and Sharpin. Here, we show that both LUBAC catalytic activity and LUBAC specificity for linear ubiquitin chain formation are embedded within the RING-IBR-RING (RBR) ubiquitin ligase subunit HOIP. Linear ubiquitin chain formation by HOIP proceeds via a two-step mechanism involving both RING and HECT E3-type activities. RING1-IBR catalyses the transfer of ubiquitin from the E2 onto RING2, to transiently form a HECT-like covalent thioester intermediate. Next, the ubiquitin is transferred from HOIP onto the N-terminus of a target ubiquitin. This transfer is facilitated by a unique region in the C-terminus of HOIP that we termed ‘Linear ubiquitin chain Determining Domain' (LDD), which may coordinate the acceptor ubiquitin. Consistent with this mechanism, the RING2-LDD region was found to be important for NF-κB activation in cellular assays. These data show how HOIP combines a general RBR ubiquitin ligase mechanism with unique, LDD-dependent specificity for producing linear ubiquitin chains. PMID:22863777

Automation system for neutron activation analysis at the reactor IBR-2, Frank Laboratory of Neutron Physics, Joint Institute for Nuclear Research, Dubna, Russia.

PubMed

Pavlov, Sergey S; Dmitriev, Andrey Yu; Frontasyeva, Marina V

The present status of development of software packages and equipment designed for automation of NAA at the reactor IBR-2 of FLNP, JINR, Dubna, RF, is described. The NAA database, construction of sample changers and software for automation of spectra measurement and calculation of concentrations are presented. Automation of QC procedures is integrated in the software developed. Details of the design are shown.

PREFACE: SANS-YuMO User Meeting at the Start-up of Scientific Experiments on the IBR-2M Reactor: Devoted to the 75th anniversary of Yu M Ostanevich's birth

NASA Astrophysics Data System (ADS)

Gordely, Valentin; Kuklin, Alexander; Balasoiu, Maria

2012-03-01

The Second International Workshop 'SANS-YuMO User Meeting at the Start-up of Scientific Experiments on the IBR-2M Reactor', devoted to the 75th anniversary of the birth of Professor Yu M Ostanevich (1936-1992), an outstanding neutron physicist and the founder of small-angle neutron scattering (field, group, and instrument) at JINR FLNPh, was held on 27-30 May at the Frank Laboratory of Neutron Physics. The first Workshop was held in October 2006. Research groups from different neutron centers, universities and research institutes across Europe presented more than 35 oral and poster presentations describing scientific and methodological results. Most of them were obtained with the help of the YuMO instrument before the IBR-2 shutdown in 2006. For the last four years the IBR-2 reactor has been shut down for refurbishment. At the end of 2010 the physical launch of the IBR-2M reactor was finally realized. Nowadays the small-angle neutron scattering (SANS) technique is applied to a wide range of scientific problems in condensed matter, soft condensed matter, biology and nanotechnology, and despite the fact that there are currently over 30 SANS instruments in operation worldwide at both reactor and spallation sources, the demand for beam-time is considerably higher than the time available. It must be remembered, however, that as the first SANS machine on a steady-state reactor was constructed at the Institute Laue Langevin, Grenoble, the first SANS instrument on a 'white' neutron pulsed beam was accomplished at the Joint Institute for Nuclear Research at the IBR-30 reactor, beamline N5. During the meeting Yu M Ostanevich's determinative and crucial contribution to the construction of spectrometers at the IBR-2 high-pulsed reactor was presented, as well as his contribution to the development of the time-of-flight (TOF) small-angle scattering technique, and a selection of other scientific areas. His leadership and outstanding scientific achievements in applications of the

A causa das estações do ano: modelos mentais

NASA Astrophysics Data System (ADS)

de Campos, J. A. S.; de Araujo, J. F. S.

2003-08-01

A década de 70 do século passado foi marcada pelo estudo das concepções alternativas que os alunos trazem para a sala de aula. A identificação destas concepções foi o ponto de partida para promover a mudança conceitual, onde as pré-concepções seriam trocadas pelas concepções científicas. Na década seguinte, surgiram muitas propostas de estratégias educacionais para facilitar esta troca, na sua maioria baseadas na idéia do conflito cognitivo, proposta por Piaget. Entretanto, os resultados pouco animadores conduziram à percepção de que a mudança conceitual é um processo mais complexo. Pelas idéias da Ciência Cognitiva, a mudança conceitual é uma mudança progressiva dos modelos mentais que o aluno tem sobre o mundo físico, através de enriquecimento e revisão. A causa das Estações do Ano é um tópico sobre o qual a maioria dos estudantes apresenta concepções alternativas. Os autores fizeram um levantamento sobre as pré-concepções encontradas em trabalhos sobre o tema (16 referências), procurando encontrar elementos comuns que indicassem a presença de modelos mentais específicos. As pré-concepções encontradas na literatura foram obtidas usando-se diversas metodologias (desde entrevistas clínicas até questionários de múltipla escolha) e envolvendo alunos e professores de diferentes regiões geográficas. A partir de uma análise aprofundada de cada trabalho, e utilizando-se a técnica das Redes Sistêmicas, chegou-se a conclusão que as diversas pré-concepções identificadas (em torno de 50), poderiam ser representadas por 6 modelos mentais, onde a explicação da causa das estações do ano tem um mecanismo causal responsável. Os mecanismos causais identificados foram: a dependência da distância, a dependência da orientação, a dependência conjunta da distância e orientação, a dependência da obstrução, a dependência da velocidade e a dependência da inclinação dos raios solares. Foram ainda identificadas

Implementación de un modelo de capacitación multimedial para brindar orientación alimentaria a los beneficiarios de un programa de ayuda social en México.

PubMed

Amaya-Castellanos, Maritza Alejandra; Morales-Ruan, María Del Carmen; Uribe-Carvajal, Rebeca; Jiménez-Aguilar, Alejandra; Salazar-Coronel, Araceli Apolonia; Martínez-Tapia, Brenda; Shamah-Levy, Teresa

2018-03-01

Introducción: Se implementó un modelo de capacitación en orientación alimentaria para la población beneficiaria y el personal operativo del Programa de Abasto Rural (PAR) de Diconsa, el cual es una iniciativa social de ayuda alimentaria que abastece productos básicos y complementarios, además de brindar capacitación en localidades de alta marginación en México. Objetivo: Documentar la utilización de la Metodología de Capacitación Multimedial (MCM) en el desarrollo de un esquema de capacitación sobre orientación alimentaria y su implementación en la población beneficiaria del PAR, a través de la propia estructura operativa del PAR. Metodología: El modelo se fundamenta en la MCM, integrada por cuatro elementos didácticos e indivisibles que conforman el paquete pedagógico multimedial (PPM), compuesto a su vez por tres videos y rotafolios, material impreso, prácticas y las relaciones interpersonales. Los ejes temáticos fueron: alimentación correcta para una vida saludable, alimentación materno-infantil, elecciones saludables y gasto familiar. El modelo fue replicado en cascada en los tres niveles operativos del PAR (responsables de capacitación, supervisores operativos y beneficiarios del PAR), con un componente de multiplicación horizontal, e implementado como piloto en cuatro estados de México. Resultados: Se observó un cambio positivo sobre los conocimientos en alimentación correcta en todos los niveles de capacitación, principalmente en los beneficiarios del PAR. La evaluación del proceso mostró conocimientos previos de los responsables de capacitación en los temas, buen desempeño como facilitadores, y habilidades de presentación y manejo del grupo de los supervisores operativos. A partir de las evaluaciones y del acompañamiento en la prueba piloto, fueron modificados las actividades, las estrategias y los materiales educativos del PPM. Conclusiones: La capacitación multimedial y la educación nutricional promueven procesos de

The Model of Optimization of Micro Energy; HOMER: El Modelo de Optimizacin de Micro energa (in Spanish)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2004-05-01

HOMER, the model of optimization of micro energy, helps to disear systems out of the network and interconnected to the network. You can use HOMER to carry out the analysis to explore an extensive rank of questions of diseo. HOMER, el modelo de optimizacin de micro energa, le ayuda a disear sistemas fuera de la red e interconectados a la red. Usted puede usar HOMER para llevar a cabo el anlisis para explorar un amplio rango de preguntas de diseo.

El rol de Ia colaboracion y el Modelo de Aprendizaje Basado en Proyectos (ABPr) mediante el lente de la Teoria de Actividad (CHAT): un estudio de caso con estudiantes de 9no grado

NASA Astrophysics Data System (ADS)

Delgado, Isabel C.

Los modelos de eensenanza y aprendizaje constructivistas conceptualizan el aprendizaje como un proceso activo. El modelo de Aprendizaje Basado en Proyectos (ABPr) se distingue por una serie de componentes, entre los cuales se destaca el aspecto colaborativo y cooperativo como un reto al momento de su implantacion. Son pocas las investigaciones que se concentran en este aspecto del modelo. En este estudio, se analizaron las diversas interacciones que surgen durante la implantacion de una unidad curricular sobre el tema de Geologia de Puerto Rico, la cual se diseno con el modelo ABPr cuyo enfoque es orientacion a proyectos. Particularmente, se examinaron las interacciones sociales que surgen entre los pares y entre pares y docente durante el proceso de planificacion y desarrollo de los productos finales, al igual que las interacciones entre los estudiantes y el material didactico en estas etapas del modelo. La investigacion es de tipo cualitativo e incorpora como diseno el estudio de caso. Las diversas interacciones constituyen la unidad de analisis. En el estudio participaron 19 estudiantes de 9no grado, a quienes se organizaron en 5 grupos colaborativos por temas de interes (Pangea, Placas tectonicas, Volcanes, Tsunamis y Terremotos). Las tecnicas que se utilizaron para recopilar los datos fueron: observaciones participativas, grupos focales y analisis de documentos (cuadernos reflexivos y respuestas de los estudiantes a la pregunta central del proyecto). Para el analisis de los datos se aplico la teoria de actividad (CHAT) que concentra la unidad de analisis en la actividad humana en un contexto particular. Los resultados del estudio senalan que las interacciones entre pares, entre pares y docente, asi como entre estudiantes y material didactico son fundamentales en el proceso de aprendizaje. Una mayor interaccion entre pares durante las etapas de planificar y desarrollar los productos finales de la unidad, promueve una mejor comprension de los conceptos de la

Modelizacion, control e implementacion de un procesador energetico paralelo para aplicacion en sistemas multisalida

NASA Astrophysics Data System (ADS)

Ferreres Sabater, Agustin

modelizacion, y aplicacion en convertidores PWM, esta aun por estudiar y valorar. El primer Capitulo consiste en una breve introduccion al problema de la regulacion cruzada y la impedancia cruzada para posteriormente describir las tecnicas de post-regulacion actualmente mas empleadas, con especial atencion al post-regulador con transformador controlado. El Capitulo segundo trata del estudio de las caracteristicas estaticas del postregulador con transformador controlado. Partiendo de los estudios disponibles sobre el postregulador se plantean mejoras en su modo de actuacion y se discuten tres alternativas diferentes para controlar el transformador. Las dos primeras consisten en emplear un convertidor auxiliar Boost en sus dos modos de funcionamiento, continuo y discontinuo. La tercera consiste en controlar el transformador con una tension PWM directamente, sin filtrado. Finalmente se comprueba experimentalmente, para el estado estacionario, el funcionamiento del post-regulador para cada uno de los tres metodos de control. El Capitulo tercero trata de la dinamica de la salida controlada con el post-regulador cuando este emplea un convertidor auxiliar tipo Boost. Mediante la tecnica de promediado de variables de estado se propone el modelo de pequena senal, tanto para el modo continuo como para el modo discontinuo de funcionamiento del convertidor auxiliar. Los resultados mas significativos de esta seccion son las expresiones analiticas de las impedancias cruzadas y de la impedancia de la salida post-regulada. Como complemento al modelo de pequena senal se plantea un modelo de gran senal implementado sobre el simulador Pspice. Con este nuevo modelo se reproducen los resultados obtenidos con el modelo de pequena senal y ademas es posible simular los transitorios en las tensiones de salida ante cambios de carga. La modelizacion del convertidor cuando el transformador se controla con una tension PWM sin filtrar es el objetivo del Capitulo 4. En las secciones siguientes del Capitulo

Epidemiology and eradication of infectious bovine rhinotracheitis/infectious pustular vulvovaginitis (IBR/IPV) virus in Finland

PubMed Central

Nuotio, Lasse; Neuvonen, Erkki; Hyytiäinen, Mauno

2007-01-01

Background Infectious bovine rhinotracheitis/infectious pustular vulvovaginitis (IBR/IPV) is a significant disease among domestic and wild cattle. The BHV-1 infection was first detected in Finland in 1970; presumably it was imported in 1968. The infection reappeared in the large-scale bulk-tank milk surveillances which started in 1990, and was eradicated in 1994. Our aim is to describe the epidemiology of this infection in Finland, and its eradication. Materials and methods The official sources of pertinent information, the legal basis for the disease control and the serological methods for the detection of the infection are described. Results and conclusion Ten AI bulls were found to be seropositive in 1970–1971. The total number of herds with BHV-1 antibody positive animals in the large-scale surveillance in 1990 and subsequent epidemiological investigations in 1991 was five, and the total number of seropositive animals was 90. The five herds formed three epidemiological units; semen of at least one bull seropositive in 1971 had been used in each unit. This remained the only plausible route of infection in each of the three units. Using the 'test and slaughter' approach and total stamping out in one herd the infection was eradicated in 1994. PMID:17222341

Thermophilic co-digestion of cattle manure and food waste supplemented with crude glycerin in induced bed reactor (IBR).

PubMed

Castrillón, L; Marañón, E; Fernández-Nava, Y; Ormaechea, P; Quiroga, G

2013-05-01

The aim of the present research work was to boost biogas production from cattle manure (CM) by adding food waste (FW) and crude glycerin (Gly) from the biodiesel industry as co-substrates. For this purpose, different quantities of FW and Gly were added to CM and co-digested in an induced bed reactor (IBR) at 55 °C. Sonication pre-treatment was implemented in the CM+Gly mixture, applying 550 kJ/kg TS to enhance the biodegradability of these co-substrates. The best results were obtained with mixtures of 87/10/3 (CM/FW/Gly) (w/w) operating at an organic loading rate of 7 g COD/L day, obtaining 92% COD removal, a specific methane yield of 640 L CH4/kg VS and a methane production rate of 2.6L CH4/L day. These results doubled those obtained in the co-digestion of CM and FW without the addition of Gly (330 L CH4/kg VS and 1.2L CH4/L day). Copyright © 2013 Elsevier Ltd. All rights reserved.

En la búsqueda de características en eyecciones coronales de masa que discriminen entre dos paradigmas físicos en modelos de ECMs

NASA Astrophysics Data System (ADS)

Paissan, G.; Stenborg, G.; Rovira, M.

Se conocen tres diferentes fenómenos de gran escala que ocurren en la atmósfera solar, denominados eyecciones coronales de masa (ECMs), protuberancias eruptivas y grandes fulguraciones de dos bandas. Estos fenómenos están estrechamente relacionados y podrían ser distintas manifestaciones de un único proceso físico. Las ECMs son definidas como eyecciones de gran escala de masa y flujo magnético desde la baja corona al espacio interplanetario. Desde su descubrimiento en los '70, muchos modelos han sido propuestos para explicar su origen y evolución. La explicación física de las ECMs es un tema de debate intenso. No obstante, los modelos pueden sintetizarse en dos grandes grupos: 1) los modelos de inyección de flujo y 2) los modelos de almacenamiento y liberación. En este trabajo, se presentan los estudios realizados con una serie de eventos observados con el coronógrafo MICA (Mirror Coronograph for Argentina), el telescopio en H-alfa HASTA (H-alpha Solar Telescope for Argentina) y los coronógrafos C2 y C3 de la sonda SOHO (Solar and Heliospheric Observatory). Los eventos que pudieron ser identificados como ECMs son contrastados dentro del esquema de los dos paradigmas teóricos propuestos.

Distribución espacial de órbitas con diferentes grados de caoticidad en modelos autoconsistentes de satélites galácticos

NASA Astrophysics Data System (ADS)

Muzzio, J. C.; Mosquera, M.

En trabajos anteriores (Carpintero et al., Cel. Mech. Dynam. Astron. 85, 247, 2003), mostramos que las órbitas caóticas son muy importantes en los satélites galácticos. Sin embargo, los únicos modelos autoconsistentes de los que se disponía para ellos eran los de Heggie-Ramamani, cuya función de distribución depende sólo de la energía por lo que no mostraban diferencias entre las distribuciones de sus órbitas regulares y caóticas. Ahora, mediante una aproximación cuadrupolar, hemos logrado construir modelos autoconsistentes de satélites galácticos con distribuciones de velocidades anisotrópicas (lo que indica que sus funciones de distribución no dependen sólo de la energía) y hemos logrado revelar las diferencias entre las estructuras espaciales de las órbitas de distinta caoticidad.

Incorporando a variabilidade no processo de identificação do modelo de máximo global no Grade of Membership (GoM): considerações metodológicas

PubMed Central

Guedes, Gilvan Ramalho; Siviero, Pamila Cristina Lima; Caetano, André Junqueira; Machado, Carla Jorge; Brondízio, Eduardo

2012-01-01

A disponibilidade de bases de dados cada vez mais complexas e multidimensionais é um dos principais motivadores para o aumento do número de estudos que utilizam análises multivariadas baseadas em lógica de conjuntos nebulosos. Apesar da disseminação do método Grade of Membership nos trabalhos empíricos brasileiros da área de ciências sociais e saúde, questões relativas à identificabilidade e estabilidade dos parâmetros finais estimados pelo programa GoM 3.4 não foram suficientemente aprofundadas. Dada a relevância de se obterem parâmetros únicos e estáveis, Guedes et al. (2010) propuseram um procedimento empírico para localizar um modelo de máximo global (MG) com parâmetros estáveis. Entretanto, seu localizador de MG não incorpora qualquer medida de variabilidade. Neste artigo, tal limitação é contornada por meio da utilização de uma estatística de ponderação – Máximo Global Ponderado (MGP) – semelhante ao coeficiente de variação. Esse indicador busca não penalizar de forma desproporcional situações nas quais os desvios médios, apesar de diferentes de zero, são muito pequenos. Apresentam-se evidências de que o localizador MGP reduz a distância do modelo identificado à real estrutura latente dos dados em análise, quando comparados ao modelo identificado pelo localizador não ponderado, MG. PMID:23293402

Vínculos observacionais para o processo-S em estrelas gigantes de Bário

NASA Astrophysics Data System (ADS)

Smiljanic, R. H. S.; Porto de Mello, G. F.; da Silva, L.

2003-08-01

Estrelas de bário são gigantes vermelhas de tipo GK que apresentam excessos atmosféricos dos elementos do processo-s. Tais excessos são esperados em estrelas na fase de pulsos térmicos do AGB (TP-AGB). As estrelas de bário são, no entanto, menos massivas e menos luminosas que as estrelas do AGB, assim, não poderiam ter se auto-enriquecido. Seu enriquecimento teria origem em uma estrela companheira, inicialmente mais massiva, que evolui pelo TP-AGB, se auto-enriquece com os elementos do processo-s e transfere material contaminado para a atmosfera da atual estrela de bário. A companheira evolui então para anã branca deixando de ser observada diretamente. As estrelas de bário são, portanto, úteis como testes observacionais para teorias de nucleossíntese pelo processo-s, convecção e perda de massa. Análises detalhadas de abundância com dados de alta qualidade para estes objetos são ainda escassas na literatura. Neste trabalho construímos modelos de atmosferas e, procedendo a uma análise diferencial, determinamos parâmetros atmosféricos e evolutivos de uma amostra de dez gigantes de bário e quatro normais. Determinamos seus padrões de abundância para Na, Mg, Al, Si, Ca, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Sr, Y, Zr, Ba, La, Ce, Nd, Sm, Eu e Gd, concluindo que algumas estrelas classificadas na literatura como gigantes de bário são na verdade gigantes normais. Comparamos dois padrões médios de abundância, para estrelas com grandes excessos e estrelas com excessos moderados, com modelos teóricos de enriquecimento pelo processo-s. Os dois grupos de estrelas são ajustados pelos mesmos parâmetros de exposição de nêutrons. Tal resultado sugere que a ocorrência do fenômeno de bário com diferentes intensidades não se deve a diferentes exposições de nêutrons. Discutimos ainda efeitos nucleossintéticos, ligados ao processo-s, sugeridos na literatura para os elementos Cu, Mn, V e Sc.

Estructura espacial de las órbitas caóticas en un modelo autoconsistente de galaxia elíptica

NASA Astrophysics Data System (ADS)

Muzzio, J. C.

Hemos logrado construir modelos autoconsistentes de sistemas estelares utilizando una aproximación cuadrupolar para el potencial. Esto nos permite determinar órbitas y exponentes de Lyapunov de objetos que tienen posiciones y velocidades equivalentes a las que se obtienen de la funcón de distribución del sistema. La distribución espacial de las órbitas caóticas exhibe considerable estructura y, lo que es más importante aún, los valores de los exponentes de Lyapunov calculados sobre intervalos finitos de tiempo, muestran una fuerte correlación con el comportamiento de la órbita en esos mismos intervalos, por lo que permiten reconocer distintos subsistemas con diferentes distribuciones espaciales.

Study of the Local Horizon. (Spanish Title: Estudio del Horizonte Local.) Estudo do Horizonte Local

NASA Astrophysics Data System (ADS)

Ros, Rosa M.

2009-12-01

The study of the horizon is fundamental to easy the first observations of the students at any education center. A simple model, to be developed in each center, allows to easy the study and comprehension of the rudiments of astronomy. The constructed model is presented in turn as a simple equatorial clock, other models (horizontal and vertical) may be constructed starting from it. El estudio del horizonte es fundamental para poder facilitar las primeras observaciones de los alumnos en un centro educativo. Un simple modelo, que debe realizarse para cada centro, nos permite facilitar el estudio y la comprensión de los primeros rudimentos astronómicos. El modelo construido se presenta a su vez como un sencillo modelo de reloj ecuatorial y a partir de él se pueden construir otros modelos (horizontal y vertical). O estudo do horizonte é fundamental para facilitar as primeiras observações dos alunos num centro educativo. Um modelo simples, que deve ser feito para cada centro, permite facilitar o estudo e a compreensão dos primeiros rudimentos astronômicos. O modelo construído apresenta-se, por sua vez, como um modelo simples de relógio equatorial e a partir dele pode-se construir outros modelos (horizontal e vertical)

Selective dry etching of III-V nitrides in Cl{sub 2}/Ar, CH{sub 4}/H{sub 2}/Ar, ICi/Ar, and IBr/Ar

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vartuli, C.B.; Pearton, S.J.; MacKenzie, J.D.

1996-10-01

The selectivity for etching the binary (GaN, AlN, and InN) and ternary nitrides (InGaN and InAlN) relative to each other in Cl{sub 2}/Ar, CH{sub 4}/H{sub 2}/Ar, ICl/Ar, or IBr/Ar electron cyclotron resonance (ECR) plasmas, and Cl{sub 2}/Ar or CH{sub 4}/H{sub 2}/Ar reactive ion (RIE) plasmas was investigated. Cl-based etches appear to be the best choice for maximizing the selectivity of GaN over the other nitrides. GaN/AlN and GaN/InGaN etch rate ratios of {approximately} 10 were achieved at low RF power in Cl{sub 2}/Ar under ECR and RIE conditions, respectively. GaN/InN selectivity of 10 was found in ICl under ECR conditions.more » A relatively high selectivity (> 6) of InN/GaN was achieved in CH{sub 4}/H{sub 2}/Ar under ECR conditions at low RF powers (50 W). Since the high bond strengths of the nitrides require either high ion energies or densities to achieve practical etch rates it is difficult to achieve high selectivities.« less

78 FR 30399 - United States v. Anheuser-Busch InBev SA/NV, Grupo Modelo S.A.B de C.V.; Proposed Final Judgment...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-22

..., Mexico. Modelo is the third-largest brewer of beer sold in the United States. Modelo's Corona Extra brand... include Corona Light, Modelo Especial, Negra Modelo, Victoria, and Pacifico. 19. ABI currently holds a 35... such as Dogfish Head, Flying Dog, and also imported beers, the best selling of which is Modelo's Corona...

INTERVENCIÓN EDUCATIVA EFECTIVA EN VIH PARA MUJERES

PubMed Central

Miner, Sarah; Poupin, Lauren; Bernales, Margarita; Ferrer, Lilian; Cianelli, Rosina

2016-01-01

RESUMEN En Chile se estima que aproximadamente 38 mil personas viven con el Virus de Inmunodeficiencia Humana [VIH]. En el año 2001, 1.092 mujeres chilenas vivían con VIH, actualmente se cree que hay más de 7.600 mujeres con el virus. Frente a estas cifras surge la necesidad de crear estrategias de prevención dirigidas a mujeres chilenas. Objetivo analizar los estudios ya realizados en la prevención de VIH para determinar qué aspectos se deben incluir en programas exitosos de prevención de VIH en mujeres. Diseño y Método se realizó una revisión de la literatura utilizando la base de datos Proquest, CINAHL, Pubmed y Scielo. Los límites comprendieron: textos completos, de los últimos 10 años, de acceso gratuito y escrito en español o inglés. Se seleccionaron 15 artículos para la revisión. Resultados todos los artículos comprenden la evaluación del efecto de una intervención sobre conocimiento y conductas relacionadas con VIH/SIDA. Catorce muestran resultados significativos en cambios positivos de conducta o conocimientos relacionados con la prevención de VIH. Conclusiones los programas de prevención de VIH en mujeres pueden ser efectivos para lograr cambios de conducta y de conocimiento. Las intervenciones exitosas son aquellas basadas en teorías o modelos de prevención y en cambios de conductas, todas adaptadas a la cultura de la población estudiada. PMID:27667897

40 CFR 1065.1010 - Reference materials.

Code of Federal Regulations, 2013 CFR

2013-07-01

... for Aviation Turbine Fuels, IBR approved for § 1065.701. (10) ASTM D1837-02a (Reapproved 2007...), IBR approved for § 1065.720. (19) ASTM D2880-03, Standard Specification for Gas Turbine Fuel Oils, IBR... Fuels and Aviation Turbine Fuels By Supercritical Fluid Chromatography, IBR approved for § 1065.703. (26...

40 CFR 1065.1010 - Reference materials.

Code of Federal Regulations, 2012 CFR

2012-07-01

... for Aviation Turbine Fuels, IBR approved for § 1065.701. (10) ASTM D1837-02a (Reapproved 2007...), IBR approved for § 1065.720. (19) ASTM D2880-03, Standard Specification for Gas Turbine Fuel Oils, IBR... Fuels and Aviation Turbine Fuels By Supercritical Fluid Chromatography, IBR approved for § 1065.703. (26...

40 CFR Table 6 to Subpart Ddddd of... - Fuel Analysis Requirements

Code of Federal Regulations, 2010 CFR

2010-07-01

... D6323-98 (2003) (for biomass) (IBR, See § 63.14(b)) or equivalent. b. Composite fuel samples... D5198-92 (2003) (for biomass) (IBR, see § 63.14(b)) or equivalent. d. Determine heat content of the fuel type * * * ASTM D5865-04 (for coal) (IBR, see § 63.24(b)) or ASTM E711-87 (for biomass) (IBR, see § 63...

Automation system for measurement of gamma-ray spectra of induced activity for multi-element high volume neutron activation analysis at the reactor IBR-2 of Frank Laboratory of Neutron Physics at the joint institute for nuclear research

NASA Astrophysics Data System (ADS)

Pavlov, S. S.; Dmitriev, A. Yu.; Chepurchenko, I. A.; Frontasyeva, M. V.

2014-11-01

The automation system for measurement of induced activity of gamma-ray spectra for multi-element high volume neutron activation analysis (NAA) was designed, developed and implemented at the reactor IBR-2 at the Frank Laboratory of Neutron Physics. The system consists of three devices of automatic sample changers for three Canberra HPGe detector-based gamma spectrometry systems. Each sample changer consists of two-axis of linear positioning module M202A by DriveSet company and disk with 45 slots for containers with samples. Control of automatic sample changer is performed by the Xemo S360U controller by Systec company. Positioning accuracy can reach 0.1 mm. Special software performs automatic changing of samples and measurement of gamma spectra at constant interaction with the NAA database.

Líneas metálicas en protuberancias solares

NASA Astrophysics Data System (ADS)

Stenborg, G.; Rovira, M. G.; Mauas, P.

Para determinar cual de los modelos existentes de protuberancias solares explica mejor las observaciones, es necesario, no solo ajustar los perfiles de las líneas de hidrógeno, sino también utilizar perfiles de distintos metales. En este trabajo, utilizamos un código desarrollado especialmente para calcular el equilibrio estadístico de cualquier especie atómica, aplicándolo al cálculo de los perfiles de las líneas del Ca II, el Mg II y el He, para determinar cómo se comportan ante variaciones en los parámetros de los modelos de protuberancia (ancho, presión y temperatura centrales y número de hebras), y comparamos con las observaciones existentes para determinar que modelo las ajusta mejor.

A prospective study on silicone breast implants and the silicone-related symptom complex.

PubMed

Contant, C M E; Swaak, A J G; Obdeijn, A I M; van der Holt, B; Tjong Joe Wai, R; van Geel, A N; Eggermont, A M M

2002-06-01

This cohort study prospectively evaluated the prevalence of the silicone-related symptom complex (SRSC) in relation to antinuclear antibodies (ANA) and magnetic resonance imaging (MRI) of silicone breast implants (SBI) 1 year after implantation. A total of 57 women undergoing mastectomy followed by immediate breast reconstruction (IBR) and SBI between March 1995 and March 1997 at the University Hospital Rotterdam/Daniel den Hoed Cancer Centre, were prospectively evaluated. Just before and 1 year after IBR the sera of these women were tested for the presence of ANA and they were screened for the prevalence of SRSC-related symptoms by questionnaire. All prostheses were evaluated by MRI 1 month and 1 year after IBR. Just before operation 11% of the women had a Sjögren score of more than 2, whereas 30% had such a score 1 year after IBR ( P = 0.01). One year postoperatively women had significantly more RA/Raynaud-related complaints: 21% preoperatively versus 40% 1 year after IBR ( P = 0.03). Within the undefined complaints-related group 19% had a score of 2 or more preoperatively and 33% 1 year after IBR ( P = 0.09). There were no new cases of ANA positivity 1 year after IBR. The linguine sign was seen by MRI in three implants: one 1 month after IBR and two 1 year after IBR. There was no relation to changes in SRSC expression and these MRI findings. In conclusion, 1 year after SBI implantation women had more SRSC-related complaints, especially Sjögren's and RA/Raynaud's. Moreover there was no correlation between elevated SRSC expression and changes in the presence of ANA or changes in MRI of the SBI 1 year after IBR.

40 CFR 63.14 - Incorporations by reference.

Code of Federal Regulations, 2010 CFR

2010-07-01

..., Heat of Combustion of Hydrocarbon Fuels by Bomb Calorimeter (High-Precision Method), IBR approved for... for Heat of Combustion of Liquid Hydrocarbon Fuels by Bomb Calorimeter (Precision Method), IBR... Oxygen Bomb Combustion/Atomic Absorption Method,1 IBR approved for table 6 to subpart DDDDD of this part...

Differentiation of Strains of Infectious Bovine Rhinotracheitis Virus by Neutralization Kinetics with Late 19S Rabbit Antibodies

PubMed Central

Potgieter, Leon N. D.; Maré, C. John

1974-01-01

Two vaccine, two respiratory (infectious bovine rhinotracheitis [IBR]), and two genital (infectious pustular vulvovaginitis [IPV]) strains of infectious bovine rhinotracheitis virus were compared by neutralization kinetics using late 19S antibody (AB). The two vaccine strains were indistinguishable from one another, but were neutralized far more rapidly than the other four strains when either anti-IBR or anti-IPV 19S AB was used. The two IPV strains were indistinguishable from one another, but were neutralized significantly more rapidly than the two IBR strains when anti-IBR 19S AB was used. The 2 IBR strains were neutralized at a similar rate with the latter globulin preparation. Almost identical results were obtained with anti-IPV 19S AB, except that one IPV strain was neutralized at a rate similar to the IBR strains. However, when early and late rabbit 7S AB were used, IBR strains could not be distinguished from IPV strains by neutralization kinetics. Preliminary experiments indicated that both early and late 19S rabbit antibodies neutralized the homologous strain more rapidly than the heterologous strain, but the difference was more noticeable with late 19S AB. It was also determined that neutralization of IBR-IPV virus by specific early and late 19S rabbit AB and early 7S rabbit AB was markedly enhanced by guinea pig complement. Neutralization of this virus by late 7S AB, however, was only slightly enhanced by complement. These results suggest that vaccine strains of IBR-IPV virus may be distinguished by neutralization kinetics with late 19S rabbit AB, and that genital and respiratory strains may possibly also be distinguishable with some 19S AB preparations. Images PMID:4372173

Patient age and breast resection weight affect immediate postmastectomy breast reconstruction in ductal carcinoma in situ.

PubMed

Burnier, Pierre; Hudry, Delphine; See, Leslie-Ann; Duvernay, Alain; Roche, Matthieu; Loustalot, Catherine; Zwetyenga, Narcisse; Coutant, Charles

2016-01-01

Mastectomy is necessary for 40% of the ductal carcinoma in situ. If immediate breast reconstruction (IBR) is systematically proposed, 81% of the patients would choose immediate versus delayed breast reconstruction, but the actual IBR rate is only approximately 50% of them. Therefore, the aim of this study was to identify objective characteristics that distinguish the patients who actually underwent IBR from those who did not. Several criteria of 248 patients who have undergone mastectomy for ductal carcinoma were analyzed. Factors studied were age, body mass index, diabetes, tobacco use, and weight of the specimen of resection. The rate of IBR was 43%. An increase in age and weight of the resection specimen, irrespective of the body mass index, was associated with a lower rate of IBR. Thus, an increase of 100 g in the weight of the breast induces a significant reduction of the IBR (33%). In our series, older patients or patients with larger breasts (irrespective of the body mass index) were less likely to undergo IBR. In order to be in line with the patient's desire, the surgeons of our unit should broaden their indications of IBR. The lack of reconstruction of large breasts should certainly be compensated in part with the recent development of free tissue transfers in our unit. 3. Copyright © 2015 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.

40 CFR 98.7 - What standardized methods are incorporated by reference into this part?

Code of Federal Regulations, 2011 CFR

2011-07-01

... 2005) Standard Practice for Automatic Sampling of Petroleum and Petroleum Products, IBR approved for... from Railroad Cars, Barges, Trucks, or Stockpiles, IBR approved for § 98.164(b). (35) ASTM D7430-08ae1... Liquids—Automatic pipeline sampling—Second Edition 1988-12-01, IBR approved for § 98.164(b). (3) [Reserved...

36 CFR 1235.4 - What publications are incorporated by reference in this part?

Code of Federal Regulations, 2011 CFR

2011-07-01

...-track magnetic tape cartridges—DLT 5 format, First Edition, December 15, 1999, IBR approved for § 1235...-track magnetic tape cartridges—DLT 6 format, First Edition, May 15, 2000, IBR approved for § 1235.46. (d... Magnetic Tape for Information Interchange (1600 CPI, PE), 1986, IBR approved for § 1235.46. (2) [Reserved...

29 CFR 1915.5 - Incorporation by reference.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Occupational and Educational Eye and Face Protection; IBR approved for § 1915.153(b)(1)(i). Copies of ANSI Z87... National Standard Practice for Occupational and Educational Eye and Face Protection; IBR approved for... Eye and Face Protection; IBR approved for § 1915.153(b)(1)(iii). (ix) ANSI Z89.1-2003, American...

48 CFR 7.105 - Contents of written acquisition plans.

Code of Federal Regulations, 2010 CFR

2010-10-01

... EVMS is required (see FAR 34.202(a)) and a pre-award IBR is contemplated, the acquisition plan must discuss— (i) How the pre-award IBR will be considered in the source selection decision; (ii) How it will... directly compensated for the costs of participating in a pre-award IBR. (4) Acquisition considerations. (i...

48 CFR 7.105 - Contents of written acquisition plans.

Code of Federal Regulations, 2014 CFR

2014-10-01

... EVMS is required (see FAR 34.202(a)) and a pre-award IBR is contemplated, the acquisition plan must discuss— (i) How the pre-award IBR will be considered in the source selection decision; (ii) How it will... directly compensated for the costs of participating in a pre-award IBR. (5) Acquisition considerations. (i...

40 CFR 60.17 - Incorporations by reference.

Code of Federal Regulations, 2010 CFR

2010-07-01

... in Petroleum Products (General Bomb Method), IBR approved for §§ 60.106(j)(2), 60.335(b)(10)(i), and... Petroleum Products (General Bomb Method), IBR approved for § 60.4415(a)(1)(i). (10) ASTM D240-76, 92, Standard Test Method for Heat of Combustion of Liquid Hydrocarbon Fuels by Bomb Calorimeter, IBR approved...

46 CFR 34.01-15 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-10-01

... for the Installation of Sprinkler Systems, IBR approved for § 34.30-1 (“NFPA 13-1996”). (2) NFPA 2001, Standard on Clean Agent Fire Extinguishing Systems, (2008 Edition), IBR approved for § 34.05-5(a)(4) (“NFPA... Specification for International Shore Connections for Marine Fire Applications, 1987, IBR approved for § 34.10...

49 CFR 173.120 - Class 3-Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... Closed Cup Tester, (ASTM D 56) (IBR; see § 171.7 of this subchapter); (B) Standard Test Methods for Flash Point of Liquids by Small Scale Closed-Cup Apparatus, (ASTM D 3278) (IBR; see § 171.7 of this subchapter... for Flash Point by Pensky-Martens Closed Cup Tester, (ASTM D 93) (IBR; see § 171.7 of this subchapter...

29 CFR 1910.6 - Incorporation by reference.

Code of Federal Regulations, 2011 CFR

2011-07-01

...-63 Safety Standard for Non-Medical X-Ray and Sealed Gamma Ray Sources, IBR approved for § 1910.252(d...). (8) ANSI A14.2-56 Safety Code for Portable Metal Ladders, Supplemented by ANSI A14.2a-77, IBR... Conveyors, Cableways, and Related Equipment, IBR approved for §§ 1910.218(j)(3); 1910.261 (a)(3)(x), (b)(1...

29 CFR 1910.6 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-07-01

...); and 1910.111(d)(1) (ii) and (iii). (6) API 650 (1966) Welded Steel Tanks for Oil Storage, 3rd Ed., IBR... and Seamless Steel Pipe, IBR approved for §§ 1910.110 and 1910.111. (3) ASTM A 126-66, Gray Iron...-1968), Alloy Steel Chain, IBR approved for § 1910.184. (5) ASTM A 395-68, Ductile Iron for Use at...

29 CFR 1910.6 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-07-01

...); and 1910.111(d)(1) (ii) and (iii). (6) API 650 (1966) Welded Steel Tanks for Oil Storage, 3rd Ed., IBR... and Seamless Steel Pipe, IBR approved for §§ 1910.110 and 1910.111. (3) ASTM A 126-66, Gray Iron...-1968), Alloy Steel Chain, IBR approved for § 1910.184. (5) ASTM A 395-68, Ductile Iron for Use at...

Hospital organizational factors affect the use of immediate breast reconstruction after mastectomy for breast cancer in the Netherlands.

PubMed

Schreuder, K; van Bommel, A C M; de Ligt, K M; Maduro, J H; Vrancken Peeters, M T F D; Mureau, M A M; Siesling, S

2017-08-01

Significant hospital variation in the use of immediate breast reconstruction (IBR) after mastectomy exists in the Netherlands. Aims of this study were to identify hospital organizational factors affecting the use of IBR after mastectomy for ductal carcinoma in situ (DCIS) or invasive breast cancer (BC) and to analyze whether these factors explain the variation. Patients with DCIS or primary invasive BC treated with mastectomy between 2011 and 2013 were selected from the national NABON Breast Cancer Audit. Hospital and organizational factors were collected with an online web-based survey. Regression analyses were performed to determine whether these factors accounted for the hospital variation. In total, 78% (n = 72) of all Dutch hospitals participated in the survey. In these hospitals 16,471 female patients underwent a mastectomy for DCIS (n = 1,980) or invasive BC (n = 14,491) between 2011 and 2014. IBR was performed in 41% of patients with DCIS (hospital range 0-80%) and in 17% of patients with invasive BC (hospital range 0-62%). Hospital type, number of plastic surgeons available and attendance of a plastic surgeon at the MDT meeting increased IBR rates. For invasive BC, higher percentage of mastectomies and more weekly MDT meetings also significantly increased IBR rates. Adjusted data demonstrated decreased IBR rates for DCIS (average 35%, hospital range 0-49%) and invasive BC (average 15%, hospital range 0-18%). Hospital organizational factors affect the use of IBR in the Netherlands. Although only partly explaining hospital variation, optimization of these factors could lead to less variation in IBR rates. Copyright © 2017 Elsevier Ltd. All rights reserved.

Influence of race, insurance status, and geographic access to plastic surgeons on immediate breast reconstruction rates.

PubMed

Butler, Paris D; Familusi, Olatomide; Serletti, Joseph M; Fox, Justin P

2018-06-01

This study evaluates the rates of immediate breast reconstruction (IBR) among racial and insurance status subgroups, in the setting of a changing plastic surgeon workforce. Using state level inpatient and ambulatory surgery data, we identified discharges for adult women who underwent mastectomy for breast cancer. This information was supplemented with plastic surgeon workforce data and aggregated to the health service area-level (HSA). Hierarchical linear models were used to risk standardized IBR rates for 8 race-payer subgroups. The final cohort included 65,246 women treated across 67 HSAs. The plastic surgeon density per 100,000 population directly related to the IBR rate. While all subgroups saw a modest increase in IBR rates, Caucasian women with private insurance realized the largest absolute increase (46%) while African-American and Asian women with public insurance saw the smallest increase (6%). Significant disparities persist in the provision of IBR according to the form of insurance a patient possesses. Of heightened concern is the novel finding that even within privately insured patients, women of color have significantly lower IBR rates compared to Caucasian women. Copyright © 2017 Elsevier Inc. All rights reserved.

Um satélite brasileiro para observação do diâmetro solar

NASA Astrophysics Data System (ADS)

Emilio, M.; Leister, N. V.; Benevides Soares, P.; Teixeira, R.; Kuhn, J.

2003-08-01

Propomos uma missão espacial para medir a forma e o diâmetro solar com o objetivo de ajudar a determinar o potencial gravitacional do Sol e a sua rotação com precisão, testar modelos teóricos de variação de energia e pela primeira vez medir os modos g de oscilação. As observações serão obtidas através do instrumento denominado APT (Astrometric and Photometric Telescope) descrito por Kuhn(1983). A sensibilidade do instrumento é de 0,2 mas em 27 dias para as observações do diâmetro solar feitas a cada minuto. Esta é uma missão de três anos de duração e pode complementar as medidas que serão feitas pelo satélite PICARD (a ser lançado em 2007). Outros parâmetros físicos podem ser obtidos com as mesmas imagens o que certamente interessará à comunidade de física solar. Um primeiro contato foi realizado com a agência espacial brasileira que pretende lançar um satélite científico a cada dois anos.

Evolução química em galáxias compactas azuis (BCGs)

NASA Astrophysics Data System (ADS)

Lanfranchi, G. A.; Matteucci, F.

2003-08-01

Neste trabalho, a formação estelar e evolução quí mica em galáxias Compactas Azuis (Blue Compact Galaxies - BCGs) foram estudadas através da comparação de previsões de modelos de evolução quí mica a várias razões de abundância quí mica observadas nestas galáxias. Modelos detalhados com recentes dados de nucleossí ntese e que levam em consideração o papel desempenahdo por supernovas de ambos os tipos (II e Ia) na evolução galáctica foram desenvolvidos para as BCGs permitindo seguir a evolução de vários elementos quí micos (H, D, He, C, N, O, Mg, Si, S, Ca, e Fe). O modelo é caracterizado pelas prescrições adotadas para a formação estelar, a qual ocorre em vários surtos de atividade separados por longos perí odos quiescentes. Após ajustar os melhores modelos aos dados observacionais, as previsões destes modelos foram comparadas também a razões de abundância observadas em sistemas Damped Lyman alpha (DLAs) e a origem do N (primária ou secundária) foi discutida. Alguns dos resultados obtidos são: i) as razões de abundância observadas nas BCGs são reproduzidas por modelos com 2 a 7 surtos de formação estelar com eficiência entre n = 0.2-0.9 Gano-1; ii) os baixos valores de N/O observados nestas galáxias são um resultado natural de uma formação estelar em surtos; iii) os modelos para BCGs podem reproduzir os dados dos DLAs, iv) uma quantidade "baixa" de N primário produzido em estrelas de alta massa pode ser uma explicação para os baixos valores de [N/a] observados em DLAs.

Modelo B/Dual Language Programmes in the Basque Country and the USA

ERIC Educational Resources Information Center

Torres-Guzman, Maria E.; Etxeberria, Feli

2005-01-01

In this paper, we undertake a cross-national comparison of early partial immersion programmes, known as dual language or Modelo B programmes, in the USA and the Basque Country in Spain, respectively. We attempt to make sense of their growth, the expanded social uses of the minority languages, and address seemingly contradictory pedagogical…

Etnografía acelerada para transformar normas sociales sobre género y sexualidad en hombres puertorriqueños heterosexuales1,2

PubMed Central

Ortiz-Torres, Blanca; Rivera-Ortiz, Rafael J.; Mendoza, Sigrid

2014-01-01

Resumen La construcción de roles de género dominantes contribuyen al riesgo de contraer VIH, y por tal razón se ha urgido a que se integren las normas sociales relativas al género en las intervenciones preventivas del VIH. Este estudio pretende adaptar y desarrollar una intervención que facilite la transformación de normas sociales del género y de prácticas sexuales en hombres puertorriqueños. La intervención propone transformar normas sociales relacionadas al género y sexualidad en barras comunitarias utilizando el modelo de líderes de opinión. Luego de ser elegidos/as, los/as líderes de opinión diseminan mensajes integrando la importancia de relaciones equitativas entre parejas para la prevención del VIH. La primera fase de esta intervención es discutida en este artículo, la cual incluye un proceso de etnografía acelerada para identificar los escenarios comunitarios en los que podemos desarrollar esta intervención y permitirnos entender la cultura de las barras comunitarias. A partir de las observaciones etnográficas, pudimos: desarrollar un protocolo de seguridad para realizar las observaciones, desarrollar un perfil de la cultura de las barras, elegir las barras a participar en las dos condiciones del estudio y adaptar los instrumentos de la intervención para que respondieran a la particularidad de los/as participantes. PMID:25530828

40 CFR 92.5 - Reference materials.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., or at http://www.ansi.org. (1) ANSI B109.1-1992, Diaphragm Type Gas Displacment Meters, IBR approved..., Standard Test Method for API Gravity of Crude Petroleum and Petroleum Products (Hydrometer Method), IBR...

40 CFR 92.5 - Reference materials.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., or at http://www.ansi.org. (1) ANSI B109.1-1992, Diaphragm Type Gas Displacment Meters, IBR approved..., Standard Test Method for API Gravity of Crude Petroleum and Petroleum Products (Hydrometer Method), IBR...

40 CFR 92.5 - Reference materials.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., or at http://www.ansi.org. (1) ANSI B109.1-1992, Diaphragm Type Gas Displacment Meters, IBR approved..., Standard Test Method for API Gravity of Crude Petroleum and Petroleum Products (Hydrometer Method), IBR...

40 CFR 61.18 - Incorporations by reference.

Code of Federal Regulations, 2010 CFR

2010-07-01

... D2382-76, 88, Heat of Combustion of Hydrocarbon Fuels by Bomb Calorimeter (High-Precision Method), IBR... Combustion of Liquid Hydrocarbon Fuels by Bomb Calorimeter (Precision Method), IBR approved for § 61.245(e)(3...

Biaxial seismic behaviour of reinforced concrete columns =

NASA Astrophysics Data System (ADS)

Rodrigues, Hugo Filipe Pinheiro

envolventes forca-deslocamento, mas foram encontradas algumas dificuldades na representacao da degradacao de resistencia e na evolucao da energia dissipada. Por fim, e proposto um modelo global para a representacao do comportamento nao-linear em flexao de elementos de betao armado sujeitos a acoes biaxiais ciclicas. Este modelo tem por base um modelo uniaxial conhecido, combinado com uma funcao de interacao desenvolvida com base no modelo de Bouc- Wen. Esta funcao de interacao foi calibrada com recurso a tecnicas de otimizacao e usando resultados de uma serie de analises numericas com um modelo refinado. E ainda demonstrada a capacidade do modelo simplificado em reproduzir os resultados experimentais de ensaios biaxiais de pilares.

40 CFR 49.123 - General provisions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Liquid Hydrocarbon Fuels by Bomb Calorimeter, IBR approved for § 49.123(a). (iv) ASTM D1826-94(Reapproved... Test Method for Gross Calorific Value of Refuse-Derived Fuel by the Bomb Calorimeter, IBR approved for...

Primary care for diabetes mellitus patients from the perspective of the care model for chronic conditions.

PubMed

Salci, Maria Aparecida; Meirelles, Betina Hörner Schlindwein; Silva, Denise Maria Guerreiro Vieira da

2017-03-09

to assess the health care Primary Health Care professionals provide to diabetes mellitus patients from the perspective of the Modelo de Atenção às Condições Crônicas. qualitative study, using the theoretical framework of Complex Thinking and the Modelo de Atenção às Condições Crônicas and the methodological framework of assessment research. To collect the data, 38 interviews were held with health professionals and managers; observation of the activities by the health teams; and analysis of 25 files of people who received this care. The data analysis was supported by the software ATLAS.ti, using the directed content analysis technique. at the micro level, care was distant from the integrality of the actions needed to assist people with chronic conditions and was centered on the biomedical model. At the meso level, there was disarticulation among the professionals of the Family Health Strategy, between them and the users, family and community. At the macro level, there was a lack of guiding strategies to implement public policies for diabetes in care practice. the implementation of the Modelo de Atenção às Condições Crônicas represents a great challenge, mainly needing professionals and managers who are prepared to work with chronic conditions are who are open to break with the traditional model. evaluar la atención de salud desarrollada por los integrantes de la Atención Primaria de Salud a las personas con diabetes mellitus en la perspectiva del Modelo de Atenção às Condições Crônicas. estudio cualitativo, con referencial teórico del Pensamiento Complejo y del Modelo de Atenção às Condições Crônicas y metodológico de la investigación evaluativa. Para recolectar los datos fueron efectuadas 38 entrevistas con profesionales de salud y gestores; observación de las actividades practicadas por los equipos de salud: y análisis de 25 archivos de personas que recibían esa atención. Los datos fueron analizados con auxilio del software

77 FR 2456 - Incorporation of Revised ASTM Standards That Provide Flexibility in the Use of Alternatives to...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-18

... (General Bomb Method), IBR approved for appendix A to subpart D. (4) ASTM D287-92, Standard Test Method for... Method for Sulfur in Petroleum Products (General Bomb Method), IBR approved for Sec. 94.108. (4) ASTM...

Sentinel lymph node biopsy before mastectomy and immediate breast reconstruction may predict post-mastectomy radiotherapy, reduce delayed complications and improve the choice of reconstruction.

PubMed

Mannu, G S; Navi, A; Morgan, A; Mirza, S M; Down, S K; Farooq, N; Burger, A; Hussien, M I

2012-01-01

Adjuvant post-mastectomy radiotherapy (RT), which is often unpredicted, is known to increase complications following immediate breast reconstruction (IBR). To investigate the role of sentinel lymph node biopsy (SLN) in predicting RT and improving the choice of IBR. All patients who had mastectomy and IBR between January 2004 and January 2007 were reviewed retrospectively. Axillary staging (clearance or SLN) was performed at the same time until October 2005 (Group 1), when the Unit's protocol was updated to perform SLN initially prior to mastectomy and IBR (Group 2). Patients in Group 2 with positive SLN were offered either a delayed reconstruction or a temporary subpectoral immediate tissue expander, while all options were offered if SLN was negative and in Group 1 patients. One hundred and thirty-nine patients were reviewed. 20 patients received unexpected RT in Group 1 (14 tissue expander, 4 Latissimus Dorsi flap with an implant and 2 DIEP flaps) compared to 11 patients in Group 2 who had a temporary tissue expander due to expected RT (P=0.03). Unexpected RT caused delayed complications in 14 patients (70%) compared to no delayed complications in patients who received expected RT in Group 2. SLN biopsy before IBR helps to predict RT and avoids its complications on breast reconstruction. Patients with positive SLN biopsy are best offered a temporary subpectoral tissue expander for IBR. Copyright © 2012 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

Desarrollo curricular, conciencia ambiental y tecnologia para estudiantes de intermedia: Una investigacion en accion

NASA Astrophysics Data System (ADS)

Rodriguez Ramos, Teresita

Se llevó a cabo una investigación en acción con los propósitos de 1) documentar las relaciones de las tecnologías de la información y la comunicación en las clases de ciencias de escuela intermedia como elemento de apoyo cuando se aborda el tema ambiental y sus conceptos pertinentes, a partir de las observaciones de la investigadora, así como las entrevistas y diarios reflexivos de los estudiantes de una escuela intermedia en la zona metropolitana, y luego 2) diseñar una unidad instruccional sobre el tema ambiental que integre actividades tecnologías para el curso de ciencias de la escuela intermedia según el modelo PROCIC y las observaciones que hayan iniciado los estudiantes participantes. Finalmente, se plantearon las implicaciones educativas para el currículo del Programa de Ciencias al instrumentar este modelo de unidad mediante PROCIC, e integrado la tecnología y el tema ambiental. Los hallazgos se analizaron y se categorizaron de acuerdo con las preguntas de investigación. El hallazgo principal de la investigación aborda las cuatro relaciones centrales en las que se articula la utilización de las tecnologías y sus aplicaciones en la clase de ciencias. Estas cuatro relaciones que recogen la posición de los estudiantes son: 1) Perspectiva de los estudiantes hacia la tecnología. 2) Participación de los estudiantes en los aspectos docentes. 3) Aprendizaje estudiantil sobre el ambiente, y 4) Conciencia ambiental en relación con la vida diaria. Estas relaciones ponen de manifiesto,cómo se plantea en las implicaciones, la necesidad de más investigación en acción en la sala de clases, la importancia—como tema transversal—de la conciencia ambiental mediante la tecnología al construir conocimientos significativos dentro y fuera de la escuela, asó como, valorar la investigación y la dialogicidad en la sala de clases como actividades que obligan al reexamen de la práctica didáctica en su formas curriculares de objetivos, recursos

Diseño de un programa basado en la promoción del desarrollo positivo en la infancia para la prevención temprana de la violencia en Colombia.

PubMed

Hernández Holguín, Dora M; Páez Zapata, Esteban; Múnera Restrepo, Laura M; Duque Ramírez, Luis F

2017-03-01

Aunque algunos informes identifiquen a Colombia como ejemplo de un país que ha logrado revertir los niveles crecientes de violencia, estos siguen siendo altos. Por este motivo se han convocado acciones de promoción de la convivencia y prevención de la violencia, a las cuales responde el programa que presentamos en este artículo. Este programa está basado en la perspectiva contextual-evolutiva del modelo ecológico y en la educación para la salud, tendiente al cuidado de sí en los padres o cuidadores, y al ejercicio de una crianza, centrada en los derechos de los niños, el desarrollo infantil y la promoción de la salud mental, con el fin de promover el desarrollo saludable y prevenir comportamientos agresivos en los niños; éste es presentado como una alternativa de orientación psicosocial para el fortalecimiento de estrategias y programas dirigidos a la primera infancia.

78 FR 54687 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-05

... Service filing seeking to include a new International Business Reply Service (IBRS) agreement within the... Postal Service seeks to include a new International Business Reply Service (IBRS) agreement (Agreement... a Functionally Equivalent International Business Reply Service Competitive Contract 3 Negotiated...

24 CFR 3280.4 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., Processes, and Services, IBR approved for §§ 3280.403(e) and 3280.405(e). (22) ANSI Z97.1-2004, Standard for... § 3280.604(b). (18) ANSI/ASME B1.20.1-1983, Pipe Threads, General Purpose (Inch), IBR approved for...

40 CFR 98.7 - What standardized methods are incorporated by reference into this part?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Liquid Hydrocarbon Fuels by Bomb Calorimeter, IBR approved for §§ 98.34(a) and 98.254(e). (5) ASTM D388... Hydrocarbon Fuels by Bomb Calorimeter (Precision Method), IBR approved for §§ 98.34(a) and 98.254(e). (25...

49 CFR 178.356-2 - Materials of construction and other requirements.

Code of Federal Regulations, 2010 CFR

2010-10-01

... DOE CAPE-1662, Rev. 1 and Supplement 1 (IBR, see § 171.7 of this subchapter). (e) Welding must be by a fusion welding process in accordance with American Welding Society Codes B-3.0 and D-1.0 (IBR, see § 171...

76 FR 10410 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-24

... recently-filed Postal Service request to add International Business Reply Service (IBRS) Competitive... International Business Reply Service (IBRS) Competitive Contract 3 to the competitive product list and... International Business Reply Service Competitive Contract 3 to the Competitive Products List and Notice of...

Disparate British Breast Reconstruction Utilization: Is Universal Coverage Sufficient to Ensure Expanded Care?

PubMed Central

Offodile, Anaeze C.

2016-01-01

Summary: Our intent is to improve the understanding of the ability of healthcare providers to deliver high-quality care as we approach an era of universal coverage. We adopted 2 unique vantage points in this article: (1) the mandated coverage for immediate breast reconstruction (IBR) surgery as a microcosmic surrogate for universal coverage overall and (2) we then scrutinized the respective IBR utilization rates in a contemporaneous system of 2 healthcare delivery models in the United Kingdom, that is, the public National Health Service trust versus private-sector hospitals. A literature review was performed for IBR rates across public trust and private-sector hospitals in the United Kingdom. The IBR rate among public trust hospitals was 17% compared with 43% in the private sector. In the trust hospital setting, the enactment of 2 government mandates, intended to increase the access to cancer care, seemed to fall short in maximizing the ability of surgical practitioners to deliver quality care to patients. Among women who did not receive IBR, 65% felt that they had received the sufficient amount of information to appropriately inform their decision. In addition, only 46% of this same cohort reported a consultation with a reconstructive surgeon preoperatively. Private-sector hospitals delivered better IBR care because of the likely presence of infrastructure and financial incentives for physicians. These results serve as a call for a better alignment between policy initiatives designed to expand care access and the perogatives of physicians to ensure an optimized delivery of the expanded care such policy mandates. PMID:27482486

Landscape influences on dispersal behaviour: a theoretical model and empirical test using the fire salamander, Salamandra infraimmaculata.

PubMed

Kershenbaum, Arik; Blank, Lior; Sinai, Iftach; Merilä, Juha; Blaustein, Leon; Templeton, Alan R

2014-06-01

When populations reside within a heterogeneous landscape, isolation by distance may not be a good predictor of genetic divergence if dispersal behaviour and therefore gene flow depend on landscape features. Commonly used approaches linking landscape features to gene flow include the least cost path (LCP), random walk (RW), and isolation by resistance (IBR) models. However, none of these models is likely to be the most appropriate for all species and in all environments. We compared the performance of LCP, RW and IBR models of dispersal with the aid of simulations conducted on artificially generated landscapes. We also applied each model to empirical data on the landscape genetics of the endangered fire salamander, Salamandra infraimmaculata, in northern Israel, where conservation planning requires an understanding of the dispersal corridors. Our simulations demonstrate that wide dispersal corridors of the low-cost environment facilitate dispersal in the IBR model, but inhibit dispersal in the RW model. In our empirical study, IBR explained the genetic divergence better than the LCP and RW models (partial Mantel correlation 0.413 for IBR, compared to 0.212 for LCP, and 0.340 for RW). Overall dispersal cost in salamanders was also well predicted by landscape feature slope steepness (76%), and elevation (24%). We conclude that fire salamander dispersal is well characterised by IBR predictions. Together with our simulation findings, these results indicate that wide dispersal corridors facilitate, rather than hinder, salamander dispersal. Comparison of genetic data to dispersal model outputs can be a useful technique in inferring dispersal behaviour from population genetic data.

DESAFÍOS ÉTICOS DE LA INVESTIGACIÓN CON ANIMALES, MANIPULACIÓN GENÉTICA

PubMed Central

Yunta, Eduardo Rodríguez

2012-01-01

En la investigación con animales existen cuestionamientos éticos tanto en el uso como modelos de enfermedades humanas y requisito previo para ensayos en humanos como en la introducción de modificaciones genéticas. Algunos de estos cuestionamientos son: no representar exactamente la condición humana como modelos, realizar pruebas de toxicidad con grave daño para los animales, alterar su naturaleza mediante modificaciones genéticas, riesgos de la introducción de organismos genéticamente modificados. El uso de animales en investigación para beneficio humano, impone al ser humano la responsabilidad moral de respetarlo, no haciéndoles sufrir innecesariamente, al estar trabajando con seres vivientes y sentientes. PMID:23338641

10 CFR 431.95 - Materials incorporated by reference.

Code of Federal Regulations, 2014 CFR

2014-01-01

... INDUSTRIAL EQUIPMENT Commercial Air Conditioners and Heat Pumps Test Procedures § 431.95 Materials... Packaged Terminal Air-Conditioners and Heat Pumps,” published September 2004 (AHRI 310/380-2004), IBR... Single Package Vertical Air-Conditioners and Heat Pumps,” dated 2003, (AHRI 390-2003), IBR approved for...

10 CFR 431.95 - Materials incorporated by reference.

Code of Federal Regulations, 2013 CFR

2013-01-01

... INDUSTRIAL EQUIPMENT Commercial Air Conditioners and Heat Pumps Test Procedures § 431.95 Materials... Packaged Terminal Air-Conditioners and Heat Pumps,” published September 2004 (AHRI 310/380-2004), IBR... Single Package Vertical Air-Conditioners and Heat Pumps,” dated 2003, (AHRI 390-2003), IBR approved for...

29 CFR 1918.3 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Archives and Records Administration (NARA). For information on the availability of this material at NARA..., American National Standard for Personal Protection—Protective Footwear; IBR approved for § 1918.104(b)(1....org. (5) ANSI Z41-1991, American National Standard for Personal Protection—Protective Footwear; IBR...

29 CFR 1918.3 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Archives and Records Administration (NARA). For information on the availability of this material at NARA..., American National Standard for Personal Protection—Protective Footwear; IBR approved for § 1918.104(b)(1....org. (5) ANSI Z41-1991, American National Standard for Personal Protection—Protective Footwear; IBR...

29 CFR 1918.3 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Archives and Records Administration (NARA). For information on the availability of this material at NARA..., American National Standard for Personal Protection—Protective Footwear; IBR approved for § 1918.104(b)(1....org. (5) ANSI Z41-1991, American National Standard for Personal Protection—Protective Footwear; IBR...

Service-Learning in Physical Education Teacher Training. Physical Education in the Modelo Prison, Barcelona

ERIC Educational Resources Information Center

Lleixà, Teresa; Ríos, Merche

2015-01-01

In the Psychiatric Unit of the Modelo Prison, Barcelona, a physical education programme is carried out annually with the participation of University of Barcelona (UB) students. In this context, we carried out a study based on service-learning parameters. The aim of the study was twofold: to determine the impact on inmates of the physical education…

Factors predictive of immediate breast reconstruction following mastectomy for invasive breast cancer in Australia.

PubMed

Roder, D; Zorbas, H; Kollias, J; Pyke, C; Walters, D; Campbell, I; Taylor, C; Webster, F

2013-12-01

To investigate person, cancer and treatment determinants of immediate breast reconstruction (IBR) in Australia. Bi-variable and multi-variable analyses of the Quality Audit database. Of 12,707 invasive cancers treated by mastectomy circa 1998-2010, 8% had IBR. This proportion increased over time and reduced from 29% in women below 30 years to approximately 1% in those aged 70 years or more. Multiple regression indicated that other IBR predictors included: high socio-economic status; private health insurance; being asymptomatic; a metropolitan rather than inner regional treatment centre; higher surgeon case load; small tumour size; negative nodal status, positive progesterone receptor status; more cancer foci; multiple affected breast quadrants; synchronous bilateral cancer; not having neo-adjuvant chemotherapy, adjuvant radiotherapy or adjuvant hormone therapy; and receiving ovarian ablation. Variations in access to specialty services and other possible causes of variations in IBR rates need further investigation. Copyright © 2013 Elsevier Ltd. All rights reserved.

MOBRAL: Un Modelo para la Educacion de Adultos?

ERIC Educational Resources Information Center

Convergence, 1974

1974-01-01

Written in Spanish, the article explains that expanding an adult basic education program, the Brazilian Literacy Movement (MOBRAL), necessitates considering the social orientation of MOBRAL in the context of Brazil and of Latin America as a whole. (AG)

40 CFR 761.19 - References.

Code of Federal Regulations, 2014 CFR

2014-07-01

... approved materials are also available for inspection at the National Archives and Records Administration...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. In addition, these... Bomb Method), IBR approved for § 761.71. (3) ASTM D240-87, Standard Test Method for Heat of Combustion...

40 CFR 761.19 - References.

Code of Federal Regulations, 2012 CFR

2012-07-01

... approved materials are also available for inspection at the National Archives and Records Administration...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. In addition, these... Bomb Method), IBR approved for § 761.71. (3) ASTM D240-87, Standard Test Method for Heat of Combustion...

40 CFR 761.19 - References.

Code of Federal Regulations, 2013 CFR

2013-07-01

... approved materials are also available for inspection at the National Archives and Records Administration...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. In addition, these... Bomb Method), IBR approved for § 761.71. (3) ASTM D240-87, Standard Test Method for Heat of Combustion...

49 CFR 384.107 - Matter incorporated by reference.

Code of Federal Regulations, 2011 CFR

2011-10-01

... (CDLIS) State Procedures Manual,” Version 4.1.0, September 2007 (“CDLIS State Procedures Manual”), IBR...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (2) Information and... Association of Motor Vehicle Administrators, Inc., 4301 Wilson Blvd, Suite 400, Arlington, VA 22203; Web site...

49 CFR 384.107 - Matter incorporated by reference.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (CDLIS) State Procedures Manual,” Version 4.1.0, September 2007 (“CDLIS State Procedures Manual”), IBR...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (2) Information and... Association of Motor Vehicle Administrators, Inc., 4301 Wilson Blvd, Suite 400, Arlington, VA 22203; Web site...

Body image issues after bilateral prophylactic mastectomy with breast reconstruction in healthy women at risk for hereditary breast cancer.

PubMed

Gopie, Jessica P; Mureau, Marc A M; Seynaeve, Caroline; Ter Kuile, Moniek M; Menke-Pluymers, Marian B E; Timman, Reinier; Tibben, Aad

2013-09-01

The outcome of bilateral prophylactic mastectomy with breast reconstruction (BPM-IBR) in healthy BRCA1/2 mutation carriers can be potentially burdensome for body image and the intimate relationship. Therefore, in the current analysis the impact on body image, sexual and partner relationship satisfaction was prospectively investigated in women opting for BPM-IBR as well as cancer distress and general quality of life. Healthy women undergoing BPM-IBR completed questionnaires preoperatively (T0, n = 48), at 6 months (T1, n = 44) and after finishing breast reconstruction (median 21 months, range 12-35) (T2, n = 36). With multi-level regression analyses the course of outcome variables was investigated and a statistically significant change in body image and/or sexual and partner relationship satisfaction was predicted by baseline covariates. Body image significantly decreased at T1. At T2 sexual relationship satisfaction and body image tended to be lower compared to baseline. The overall partner relationship satisfaction did not significantly change. At T2, 37 % of the women reported that their breasts felt unpleasantly, 29 % was not satisfied with their breast appearance and 21 % felt embarrassed for their naked body. Most body image issues remained unchanged in 30 % of the women. A negative body image was predicted by high preoperative cancer distress. BPM-IBR was associated with adverse impact on body image in a substantial subgroup, but satisfaction with the overall sexual and partner relationship did not significantly change in time. The psychosocial impact of BPM-IBR in unaffected women should not be underestimated. Psychological support should ideally be integrated both before and after BPM-IBR.

29 CFR 1910.6 - Incorporation by reference.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Manufacture of Organic Coatings, IBR approved for § 1910.106(j)(6)(ii). (7) NFPA 36-1967 Standard for Solvent... 20006: (1) Definition and Test Procedures for Ammonium Nitrate Fertilizer (Nov. 1964), IBR approved for... is available for purchase from the Fertilizer Institute, 1015 18th Street NW, Washington, DC 20036...

29 CFR 1917.3 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-07-01

...). For information on the availability of this material at NARA, telephone: 202-741-6030, or go to http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. Also, the material..., American National Standard for Personal Protection—Protective Footwear; IBR approved for § 1917.94(b)(1)(ii...

29 CFR 1917.3 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-07-01

...). For information on the availability of this material at NARA, telephone: 202-741-6030, or go to http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. Also, the material..., American National Standard for Personal Protection—Protective Footwear; IBR approved for § 1917.94(b)(1)(ii...

29 CFR 1917.3 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-07-01

...). For information on the availability of this material at NARA, telephone: 202-741-6030, or go to http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. Also, the material..., American National Standard for Personal Protection—Protective Footwear; IBR approved for § 1917.94(b)(1)(ii...

40 CFR 260.11 - References.

Code of Federal Regulations, 2011 CFR

2011-07-01

...). (7) ASTM E 168-88, “Standard Practices for General Techniques of Infrared Quantitative Analysis,” IBR...-Visible Quantitative Analysis,” IBR approved for § 264.1063. (9) ASTM E 260-85, “Standard Practice for... materials are available for purchase from the Environmental Protection Agency, Research Triangle Park, NC...

10 CFR 431.323 - Materials incorporated by reference.

Code of Federal Regulations, 2011 CFR

2011-01-01

... of Energy, Office of Energy Efficiency and Renewable Energy, Building Technologies Program, 6th Floor... National Standard for electric lamps: Single-Ended Metal Halide Lamps, approved May 5, 2004, IBR approved... (“NFPA 70”), National Electrical Code 2002 Edition, IBR approved for § 431.326; (2) [Reserved] (e) UL...

10 CFR 431.323 - Materials incorporated by reference.

Code of Federal Regulations, 2013 CFR

2013-01-01

... of Energy, Office of Energy Efficiency and Renewable Energy, Building Technologies Program, 6th Floor... National Standard for electric lamps: Single-Ended Metal Halide Lamps, approved May 5, 2004, IBR approved... (“NFPA 70”), National Electrical Code 2002 Edition, IBR approved for § 431.326; (2) [Reserved] (e) UL...

Generating para-water from para-hydrogen: A Gedankenexperiment.

PubMed

Ivanov, Konstantin L; Bodenhausen, Geoffrey

2018-07-01

A novel conceptual approach is described that is based on the transfer of hyperpolarization from para-hydrogen in view of generating a population imbalance between the two spin isomers of H 2 O. The approach is analogous to SABRE (Signal Amplification By Reversible Exchange) and makes use of the transfer of spin order from para-hydrogen to H 2 O in a hypothetical organometallic complex. The spin order transfer is expected to be most efficient at avoided level crossings. The highest achievable enrichment levels of para- and ortho-water are discussed. Copyright © 2018 Elsevier Inc. All rights reserved.

Condiciones Físicas en Nebulosas Gaseosas

NASA Astrophysics Data System (ADS)

Luridiana, V.

1999-03-01

El presente trabajo se ha enfocado a determinar y entender las condiciones físicas en una variedad de objetos nebulares, prestando particular atención al problema de la determinación de las abundancias químicas. Para este fin, hemos utilizado métodos analíticos en algunos casos, y modelos numéricos de fotoionización en otros. El objetivo general del trabajo es proveer de una visión amplia de las herramientas teórico-observacionales que se utilizan para la determinación de la estructura de temperatura y densidad de las regiones fotoionizadas, poniendo en evidencia posibles fuentes de errores sistemáticos y sus consecuencias para la determinación de las abundancias químicas, y proponiendo métodos para corregirlos. Los resultados principales de este trabajo est´n listados a continuación: a) Se discute el problema de la discrepancia entre T(C III) y T(O III) en las nebulosas planetarias, y se muestra como tal discrepancia implica probablemente la presencia de fluctuaciones de temperatura. Debido a que la temperatura de O++ es muy afectada por fluctuaciones de temperatura, se recomienda usar la temperatura de C++ para determinar la abundancia de carbono. b) Presentamos dos nuevos métodos para determinar la temperatura electrónica en nebulosas planetarias, basados en la medición de las intensidades de las líneas de He I. Las temperaturas que se obtienen a partir de estos métodos son menores que aquellas que se obtienen a partir de las líneas de [O III], implicando la presencia de fluctuaciones espaciales de temperatura. Despreciando las fluctuaciones de temperatura, se obtienen valores sesgados de las abundancias químicas. Determinamos las abundancias en las nebulosas planetarias de tipo I de algunos de los elementos más importantes, tomando en cuenta las fluctuaciones de temperatura. c) Presentamos modelos numéricos de las dos regiones H II extragalácticas gigantes NGC 2363 y NGC 5461. Con el modelaje numérico, pretendemos acotar las car

Desarrollo de un instrumento para medir percepciones sobre el contexto de construccion del conocimiento cientifico de estudiantes universitarios de nuevo ingreso

NASA Astrophysics Data System (ADS)

Garcia-Ramirez, Jaime Antonio

En esta investigacion, se desarrollo un instrumento que permite medir percepciones relacionadas al contexto de constriccion del conocimiento cientifico. Se examinaron instrumentos existentes y se encontro que el VOSTS (Views on science, technology, and society), instrumento desarrollado empiricamente en Canada por Aikenhead, Ryan y Fleming, podia traducirse y validarse en el contexto cultural puertorriqueno. El instrumento es extenso, consta de 113 reactivos, cada uno con una premisa basica relacionada a la tematica ciencia, tecnologia y sociedad y un numero de alternativas relacionadas a la premisa que oscila entre siete y trece. Se delimito su utilizacion a los quince reactivos identificados por los autores como relacionados a la construccion social del conocimiento cientifico. Metodologicamente, se procedio a utilizar el modelo de adaptacion intercultural, que permite que el instrumento desarrollado satisfaga las dimensiones de equivalencia semantica, de contenido, tecnica, de criterio y conceptual, atemperado asi al instrumento original. Se cumplio con este proposito mediante la traduccion de la version original en ingles al espanol y viceversa. Se utilizaron comites para examinar la traduccion y la retro-traduccion del instrumento. Se realizo una prueba piloto con estudiantes universitarios de nuevo ingreso, utilizando el instrumento traducido para asegurar su intelegibilidad. La confiabilidad del instrumento se determino mediante la intervencion de un panel de expertos quienes clasificaron las distintas posiciones dentro de cada reactivo en: realista, con merito e ingenua; se transformaron estas opciones en valores numericos lo que permitio establecer una escala Likert para cada una. Se suministro el instrumento a una muestra de estudiantes universitarios de nuevo ingreso con caracteristicas similares a las de la poblacion puertorriquena en cuanto a ejecucion en las pruebas de aptitud verbal y matematica del College Board. Los resultados de sus contestaciones

Evolución de estrellas enanas blancas de Helio de masa baja e intermedia

NASA Astrophysics Data System (ADS)

Althaus, L. G.; Benvenuto, O. G.

Numerosas observaciones realizadas particularmente en los últimos dos años parecen confirmar que las enanas blancas (EB) de helio de masa baja e intermedia son el resultado de la evolución de sistemas binarios cercanos. Con el objeto de realizar una adecuada interpretación de estos objetos son necesarios modelos de EBs de helio lo más detallado posibles. En este estudio presentamos cálculos detallados de la evolución de EBs de helio con masas entre M=0.1Msolar y M=0.5Msolar a intervalos de 0.05Msolar . Para ello, hemos tenido en cuenta los efectos de temperatura finita mediante un código de evolución estelar lo más actualizado posible. En particular, el transporte de energía es descripto en el marco del nuevo modelo para la convección turbulenta desarrollado por Canuto - Mazzitelli. Además hemos considerado la nueva ecuación de estado para plasmas de helio de Saumon et al. y nuevas opacidades radiativas OPAL. Las pérdidas por neutrinos fueron asimismo tenidas en cuenta. Excepto para las EBs más masivas, nuestros modelos iniciales están ubicados en las cercanías de la correspondiente línea de Hayashi para configuraciones de helio. Nuestros resultados muestran que existe una región prohibida en el diagrama observacional HR donde ninguna EB de helio puede encontrarse. Dicha región es para log{(L/Lsolar )}>= -0.25 and log{Teff} >= 4.45. Hemos encontrado también que los tracks evolutivos en el diagrama HR en el dominio de alta luminosidad (pre - EB) son fuertemente afectados por la eficiencia convectiva y que las pérdidas por neutrinos son importantes en los modelos más masivos. Finalmente hemos analizado la estructura de la zona convectiva externa encontrando que la teoría de Canuto - Mazzitelli conduce a un perfil convectivo muy diferente del dado por cualquier versión de la popular teoría de la mixing length. Si bién este comportamiento es decisivo en el contexto de las inestabilides pulsacionales, los radios y gravedades superficiales de

49 CFR 179.200-7 - Materials.

Code of Federal Regulations, 2010 CFR

2010-10-01

... suitable for welding and comply with one of the following specifications (IBR, see § 171.7 of this... to testing. (A typical sensitizing treatment is 1 hour at 1250 F.) (e) Nickel plate: Nickel plate... must be suitable for fusion welding and comply with the following specification (IBR, see § 171.7 of...

49 CFR 173.137 - Class 8-Assignment of packing group.

Code of Federal Regulations, 2012 CFR

2012-10-01

... the Testing of Chemicals, Number 435, “In Vitro Membrane Barrier Test Method for Skin Corrosion” (IBR... Guideline for the Testing of Chemicals, Number 430, “In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test (TER)” (IBR, see § 171.7 of this subchapter) or Number 431, “In Vitro Skin Corrosion: Human...

49 CFR 173.137 - Class 8-Assignment of packing group.

Code of Federal Regulations, 2011 CFR

2011-10-01

... the Testing of Chemicals, Number 435, “In Vitro Membrane Barrier Test Method for Skin Corrosion” (IBR... Guideline for the Testing of Chemicals, Number 430, “In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test (TER)” (IBR, see § 171.7 of this subchapter) or Number 431, “In Vitro Skin Corrosion: Human...

40 CFR 260.11 - References.

Code of Federal Regulations, 2012 CFR

2012-07-01

...). (7) ASTM E 168-88, “Standard Practices for General Techniques of Infrared Quantitative Analysis,” IBR...-Visible Quantitative Analysis,” IBR approved for § 264.1063. (9) ASTM E 260-85, “Standard Practice for..., Research Triangle Park, NC. (1) “Screening Procedures for Estimating the Air Quality Impact of Stationary...

40 CFR 260.11 - References.

Code of Federal Regulations, 2014 CFR

2014-07-01

...). (7) ASTM E 168-88, “Standard Practices for General Techniques of Infrared Quantitative Analysis,” IBR...-Visible Quantitative Analysis,” IBR approved for § 264.1063. (9) ASTM E 260-85, “Standard Practice for..., Research Triangle Park, NC. (1) “Screening Procedures for Estimating the Air Quality Impact of Stationary...

40 CFR 260.11 - References.

Code of Federal Regulations, 2013 CFR

2013-07-01

...). (7) ASTM E 168-88, “Standard Practices for General Techniques of Infrared Quantitative Analysis,” IBR...-Visible Quantitative Analysis,” IBR approved for § 264.1063. (9) ASTM E 260-85, “Standard Practice for..., Research Triangle Park, NC. (1) “Screening Procedures for Estimating the Air Quality Impact of Stationary...

27 CFR 21.6 - Incorporations by reference.

Code of Federal Regulations, 2010 CFR

2010-04-01

..._regulations/ibr_locations.html. (b) Material from Parts 23, 25, and 29 of the 1980 Annual Book of ASTM..._locations.html. (c) Material from the “Official Methods of Analysis of the Association of Official.../federal_register/code_of_federal_regulations/ibr_locations.html. [T.D. ATF-133, 48 FR 24673, June 2, 1983...

40 CFR 600.011 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 1, 2010, IBR approved for §§ 600.113-08(f) and 600.113-12(f). (c) Society of Automotive Engineers... 1100a (Report of Human Factors Engineering Committee, Society of Automotive Engineers, approved September 1973 as revised September 1975), IBR approved for § 600.315-08(c). (2) SAE J1634, Electric Vehicle...

40 CFR 600.011 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 1, 2010, IBR approved for §§ 600.113-08(f) and 600.113-12(f). (c) Society of Automotive Engineers... 1100a (Report of Human Factors Engineering Committee, Society of Automotive Engineers, approved September 1973 as revised September 1975), IBR approved for § 600.315-08(c). (2) SAE J1634, Electric Vehicle...

40 CFR 61.18 - Incorporations by reference.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Gasoline by Gas Chromatography, IBR approved September 30, 1986, for § 61.67(h)(1). (6) ASTM D2359-85a, 93... in C3 and Lighter Hydrocarbon Products by Gas Chromatography, IBR approved June 6, 1984 for § 61.245... D4420-94, Standard Test Method for Determination of Aromatics in Finished Gasoline by Gas Chromatography...

46 CFR 164.120-5 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-10-01

...), IBR approved for § 164.120-7 (“ASTM D 543”). (2) ASTM D 570-98 (Reapproved 2005), Standard Test Method for Water Absorption of Plastics, (approved November 1, 2005), IBR approved for § 164.120-7 (“ASTM D 570”). (3) ASTM D 638-08, Standard Test Method for Tensile Properties of Plastics, (approved April 1...

47 CFR 76.602 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-10-01

... MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Technical Standards § 76.602 Incorporation by reference. (a... System,” 2003, IBR approved for § 76.640. (4) ANSI/SCTE 54 2003 (formerly DVS 241), “Digital Video... Protection System,” 2003, IBR approved for § 76.640. (5) ANSI/SCTE 54 2003 (formerly DVS 241), “Digital Video...

46 CFR 160.156-5 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., Standard Specification for Carbon Structural Steel, (approved May 15, 2008), IBR approved for §§ 160.156-7 and 160.156-15 (“ASTM A 36”). (2) ASTM A 276-08a, Standard Specification for Stainless Steel Bars and..., (approved October 1, 2008), Standard Specification for Stainless Steel Spring Wire, IBR approved for § 160...

46 CFR 160.156-5 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-10-01

..., Standard Specification for Carbon Structural Steel, (approved May 15, 2008), IBR approved for §§ 160.156-7 and 160.156-15 (“ASTM A 36”). (2) ASTM A 276-08a, Standard Specification for Stainless Steel Bars and..., (approved October 1, 2008), Standard Specification for Stainless Steel Spring Wire, IBR approved for § 160...

46 CFR 160.156-5 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 36M-08, Standard Specification for Carbon Structural Steel, (approved May 15, 2008), IBR approved for §§ 160.156-7 and 160.156-15 (“ASTM A 36”). (2) ASTM A 276-08a, Standard Specification for Stainless Steel... 313/A 313M-08, (approved October 1, 2008), Standard Specification for Stainless Steel Spring Wire, IBR...

Estudo de não gaussianidade nas anisotropias da RCF medidas Wmap

NASA Astrophysics Data System (ADS)

Andrade, A. P. A.; Wuensche, C. A.; Ribeiro, A. L. B.

2003-08-01

A investigação do campo de flutuações da Radiação Cósmica de Fundo (RCF) pode oferecer um importante teste para os modelos cosmológicos que descrevem a origem e a evolução das flutuações primordiais. De um lado, apresenta-se o modelo inflacionário que prevê um espectro de flutuações adiabáticas distribuídas segundo uma gaussiana e, de outro, os modelos de defeitos topológicos (dentre outros) que descrevem um mecanismo para a geração de flutuações de isocurvatura que obedecem a uma distribuição não gaussiana. Este trabalho tem como objetivo caracterizar traços do modelo não gaussiano de campo misto (entre flutuações adiabáticas e de isocurvatura) nos mapas do Wilkinson Microwave Anisotropy Probe (WMAP). Simulações das anisotropias da RCF no contexto de mistura indicam traços marcantes na distribuição das flutuações de temperatura, mesmo quando consideradas pequenas contribuições do campo de isocurvatura (da ordem de 0.001). O efeito da mistura entre os campos resulta na transferência de potência de flutuações em escalas angulares intermediárias para flutuações em pequenas escalas angulares. Este efeito pode ser caracterizado pela relação entre as amplitudes dos primeiros picos acústicos no espectro de potência da RCF. Neste trabalho, investigamos a contribuição do campo de isocurvatura, no contexto de mistura, sobre as observações recentes da RCF realizadas pelo WMAP. As previsões do modelo de campo misto, uma vez confrontadas com as observações em pequenas escalas angulares, podem ajudar a revelar a natureza das flutuações primordiais.

Simulating Asymmetric Top Impurities in Superfluid Clusters: A para-Water Dopant in para-Hydrogen.

PubMed

Zeng, Tao; Li, Hui; Roy, Pierre-Nicholas

2013-01-03

We present the first simulation study of bosonic clusters doped with an asymmetric top molecule. The path-integral Monte Carlo method with the latest methodological advance in treating rigid-body rotation [Noya, E. G.; Vega, C.; McBride, C. J. Chem. Phys.2011, 134, 054117] is employed to study a para-water impurity in para-hydrogen clusters with up to 20 para-hydrogen molecules. The growth pattern of the doped clusters is similar in nature to that of pure clusters. The para-water molecule appears to rotate freely in the cluster. The presence of para-water substantially quenches the superfluid response of para-hydrogen with respect to the space-fixed frame.

Analisis experimental de la propagacion en redes de area corporal para la banda de ultra wideband. experimental characterization of the propagation in ultra wideband body area networks

NASA Astrophysics Data System (ADS)

Garcia Serna, Ruben Gregorio

Diferentes dispositivos capaces de obtener informacion sobre parametros fisiologicos, cinematicos o contextuales del cuerpo pueden interconectarse de manera inalambrica dando lugar a las denominadas Redes de Area Corporal Inalambricas (WBAN, Wireless Body Area Networks). De entre las posibles tecnologias para establecer los enlaces, Ultra Wideband (UWB) esta captando cada vez un mayor interes debido a caracteristicas tales como el bajo nivel de potencia de transmision requerido (bajo nivel de exposicion a campos electromagneticos), el alto ancho de banda disponible y la alta resolucion temporal/espacial. El diseno de sistemas centrados en el cuerpo requiere de modelos de canal que describan de manera precisa la propagacion de senales en este tipo de entornos. Esta tesis se plantea con el objetivo de contribuir al estudio experimental de la propagacion en sistemas centrados en el cuerpo operando en la banda UWB. En primer lugar, se presenta un marco introductorio a las redes WBAN, sus elementos constitutivos, bandas de frecuencia, estandarizacion y modelos de canal. Ademas, se introducen los fundamentos de la tecnologia UWB y sus aplicaciones en este area. Seguidamente, se analiza en terminos de las perdidas de propagacion y la dispersion de retardo la propagacion en el canal off-body entre un transmisor fijo y un dispositivo receptor colocado sobre la superficie del cuerpo de un sujeto. Se considera la influencia de diferentes aspectos, tales como el entorno de medidas, la posicion de colocacion de una antena sobre el cuerpo y la postura adoptada por un sujeto. Finalmente, se analiza el canal de propagacion in-body considerando el movimiento relativo entre dos dispositivos causado por efecto de la respiracion. Las condiciones de propagacion en el interior del cuerpo se emulan por medio de un phantom liquido para UWB y la caracterizacion se plantea tanto en frecuencia, en terminos del modelado de la forma y el ensanchamiento del espectro Doppler, como en tiempo, por

46 CFR 160.135-5 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Polyester, High Strength, Flexible, (May 13, 1997), IBR approved for §§ 160.135-7 and 160.135-15. (“A-A... Specification for Carbon Structural Steel, (approved May 15, 2008), IBR approved for §§ 160.135-7 and 160.135-15 (“ASTM A 36”). (2) ASTM A 276-08a, Standard Specification for Stainless Steel Bars and Shapes, (approved...

46 CFR 160.135-5 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-10-01

... Polyester, High Strength, Flexible, (May 13, 1997), IBR approved for §§ 160.135-7 and 160.135-15. (“A-A... Specification for Carbon Structural Steel, (approved May 15, 2008), IBR approved for §§ 160.135-7 and 160.135-15 (“ASTM A 36”). (2) ASTM A 276-08a, Standard Specification for Stainless Steel Bars and Shapes, (approved...

46 CFR 160.135-5 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-10-01

..., Vinyl Nylon Or Polyester, High Strength, Flexible, (May 13, 1997), IBR approved for §§ 160.135-7 and 160... for Carbon Structural Steel, (approved May 15, 2008), IBR approved for §§ 160.135-7 and 160.135-15 (“ASTM A 36”). (2) ASTM A 276-08a, Standard Specification for Stainless Steel Bars and Shapes, (approved...

29 CFR 1926.6 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Prevention Tags, IBR approved for § 1926.200(i). (26) ANSI Z49.1-1967, Safety in Welding and Cutting, IBR... approved for § 1926.603(a). (m) The following material is available for purchase from the American Welding...://www.aws.org/: (1) AWS D1.1/D1.1M:2002, Structural Welding Code—Steel, 18th ed., ANSI approved Aug. 31...

Providing Meaningful Learning for Students of the Sixth Grade of Middle School: a Study on the Moon Phases. (Breton Title: Propiciando Aprendizagem Significativa Para Alunos do Sexto Ano do Ensino Fundamental: um Estudo sobre as Fases da Lua.) Propiciando el Aprendizaje Significativo Para Alumnos del Sexto Nivel de la Educación General Básica: un Estudio sobre Las Fases de la Luna

NASA Astrophysics Data System (ADS)

Darroz, Luiz Marcelo; Samudio Pérez, Carlos Ariel; da Rosa, Cleci Werner; Heineck, Renato

2012-07-01

We relate in this article a didactic experience studying the moon phases with a group of middle school students of a private school of the municipality of Passo Fundo, RS. Based on David Ausubel's Meaningful Learning Theory, we have sought to develop a proposal following a didactic model which simulates the phases of the Moon, as based on the previous conceptions of the students. The signs of learning were evidenced by means of memory registries of the activity. From the obtained results we believe that the proposal achieved its goals, since the students were able to identify, differentiate and transfer the phenomenon of the moon phases to new contexts. Thus, it is concluded that a methodology focused on a meaningful content for the students is fundamental to the construction and genuine grasping of what is being learned. Neste artigo, relata-se uma experiência didática de estudo das fases da Lua com uma turma do 6° ano do Ensino Fundamental, de uma escola privada do município de Passo Fundo, RS. Tendo como fundamentação teórica a Teoria da Aprendizagem Significativa de David Ausubel, buscou-se desenvolver a proposta a partir de um modelo didático que simula as fases da Lua e com base nas concepções prévias dos estudantes. Os indícios da aprendizagem foram constatados através de registros de memórias da atividade. Pelos resultados apresentados, acredita-se que a proposta alcançou seus objetivos, uma vez que os estudantes conseguiram identificar, diferenciar e transferir o fenômeno das fases da Lua para novos contextos. Assim, conclui-se que uma metodologia com enfoque em um conteúdo significativo ao estudante é fundamental para a construção e compreensão genuína do que está sendo aprendido. En este artículo se relata una experiencia didáctica de estudio de las fases de la Luna con una clase de 6º año de la educación general básica de una escuela privada del municipio de Passo Fundo, RS. Teniendo como fundamentación teórica la Teor

Analysis of arsenic and mercury content in human remains of the 16th and 17th centuries from Moscow Kremlin necropolises by neutron activation analysis at the IREN facility and the IBR-2 reactor FLNP JINR

NASA Astrophysics Data System (ADS)

Panova, T. D.; Dmitriev, A. Yu.; Borzakov, S. B.; Hramco, C.

2018-01-01

A neutron activation analysis (NAA) of three samples of human remains of the 16th and 17th centuries from the necropolises of the Moscow Kremlin has been carried out at FLNP JINR. The samples were irradiated at two facilities: the IREN source of resonance neutrons and the IBR-2 reactor. Spectra of the induced activity of the irradiated samples were measured by using the automatic measurement system developed at the Frank Laboratory of Neutron Physics (FLNP) of the Joint Institute for Nuclear Research (JINR). This system consists of a high-purity germanium detector with spectrometric electronics, a sample changer, and control software. Mass fraction of arsenic, mercury, and some other elements were calculated using two NAA methods—relative and absolute. The obtained values confirm the fact of acute mercury poisoning of Anastasia Romanovna, the first wife of Tsar Ivan Vasil'evich the Terrible, the first Russian Tsarina (died in 1560). High levels of mercury were detected in the bone remains of Tsarevich Ivan Ivanovich (died in 1581), the son of Tsar Ivan the Terrible, and Prince Mikhail Vasil'evich Skopin-Shuiskii (died in 1610). The results provide an opportunity to introduce into scientific circulation the exact values of mass fraction of mercury, arsenic, and other elements in the samples taken from the burials of the Russian historical figures of the second half of 16th-early 17th century.

Immediate reconstruction with implants in women with invasive breast cancer does not affect oncological safety in a matched cohort study.

PubMed

Eriksen, C; Frisell, J; Wickman, M; Lidbrink, E; Krawiec, K; Sandelin, K

2011-06-01

Physicians are still concerned about the oncological safety regarding immediate breast reconstruction (IBR) in breast cancer patients. This study aimed to evaluate possible differences between local, regional, and distant recurrences between women having implant-based reconstruction versus women operated with mastectomy alone. Secondary aims were to evaluate time to oncological treatment as well as disease-free and breast-cancer-specific survival. In a retrospective cohort designed study, 300 reconstructed patients with invasive breast cancer were matched with 300 patients from the population-based Regional Breast Cancer Register of the Stockholm-Gotland health-care region operated with mastectomy alone. They were matched for age, tumor size, nodal stage, and year of operation. Also included were patients treated with neoadjuvant chemotherapy and postoperative radiotherapy. The median follow-up for both the groups was 11.5 years (range 2-20). There were no significant differences in the local recurrence rate, 8.2% in the IBR group and 9.0% in the control group or in the regional recurrence rate, 8.2% versus 9.7%. Distant metastases occurred more frequently in the control group (27.1%) when compared to the IBR group (20.3%). There were no significant differences in time to treatment or in complications rate. Breast cancer mortality was 17% for the IBR group and 23% in the control group during follow-up. This long-term follow-up survey with a well-matched control group demonstrates that IBR with implants is safe to offer patients with invasive breast cancer without any negative effect on the oncological safety.

Variation in rates of breast cancer surgery: A national analysis based on French Hospital Episode Statistics.

PubMed

Rococo, E; Mazouni, C; Or, Z; Mobillion, V; Koon Sun Pat, M; Bonastre, J

2016-01-01

Minimum volume thresholds were introduced in France in 2008 to improve the quality of cancer care. We investigated whether/how the quality of treatment decisions in breast cancer surgery had evolved before and after this policy was implemented. We used Hospital Episode Statistics for all women having undergone breast conserving surgery (BCS) or mastectomy in France in 2005 and 2012. Three surgical procedures considered as better treatment options were analyzed: BCS, immediate breast reconstruction (IBR) and sentinel lymph node biopsy (SLNB). We studied the mean rates and variation according to the hospital profile and volume. Between 2005 and 2012, the volume of breast cancer surgery increased by 11% whereas one third of the hospitals no longer performed this type of surgery. In 2012, the mean rate of BCS was 74% and similar in all hospitals whatever the volume. Conversely, IBR and SLNB rates were much higher in cancer centers (CC) and regional teaching hospitals (RTH) [IBR: 19% and 14% versus 8% on average; SLNB: 61% and 47% versus 39% on average]; the greater the hospital volume, the higher the IBR and SLNB rates (p < 0.0001). Overall, whatever the surgical procedure considered, inter-hospital variation in rates declined substantially in CC and RTH. We identified considerable variation in IBR and SLNB rates between French hospitals. Although more complex and less standardized than BCS, most clinical guidelines recommended these procedures. This apparent heterogeneity suggests unequal access to high-quality procedures for women with breast cancer. Copyright © 2015 Elsevier Ltd. All rights reserved.

40 CFR 80.1468 - Incorporation by reference.

Code of Federal Regulations, 2010 CFR

2010-07-01

....astm.org). (1) ASTM D 1250-08 (“ASTM D 1250”), Standard Guide for Use of the Petroleum Measurement Tables, Approved 2008; IBR approved for § 80.1426(f)(8)(ii)(B). (2) ASTM D 4442-07 (“ASTM D 4442... 2007; IBR approved for § 80.1426(f)(7)(v)(B). (3) ASTM D 4444-08 (“ASTM D 4444”), Standard Test Method...

Un modelo de dínamo para ɛ Eridani

NASA Astrophysics Data System (ADS)

Sraibman, L.; Buccino, A. P.; Minotti, F.

2017-10-01

Eridani is an active young K2V star (0.8 Gyr), which exhibits a short and long-term chromospheric cycles of 3 and 13-yr periods, between 1985 and 1992, the star went through a broad activity minimum, similar to the solar Maunder Minimum-state. Motivated by these results, we found in Eridani a great opportunity to test the solar cinematic dynamo model built in sraibman16. In this work we present the components of the magnetic fields in the stellar surface derived from the model. To contrast these results to the registry of activity obtained from stellar observations, we also computed an activity index associated to the magnetic field.

Chemical Ligation Reactions of Oligonucleotides for Biological and Medicinal Applications.

PubMed

Abe, Hiroshi; Kimura, Yasuaki

2018-01-01

Chemical ligation of oligonucleotides (ONs) is the key reaction for various ON-based technologies. We have tried to solve the problems of RNA interference (RNAi) technology by applying ON chemical ligation to RNAi. We designed a new RNAi system, called intracellular buildup RNAi (IBR-RNAi), where the RNA fragments are built up into active small-interference RNA (siRNA) in cells through a chemical ligation reaction. Using the phosphorothioate and iodoacetyl groups as reactive functional groups for the ligation, we achieved RNAi effects without inducing immune responses. Additionally, we developed a new chemical ligation for IBR-RNAi, which affords a more native-like structure in the ligated product. The new ligation method should be useful not only for IBR-RNAi but also for the chemical synthesis of biofunctional ONs.

Elastoplasticidad anisotropa de metales en grandes deformaciones

NASA Astrophysics Data System (ADS)

Caminero Torija, Miguel Angel

El objetivo de este trabajo es el desarrollo de modelos y algoritmos numericos que simulen el comportamiento del material bajo estas condiciones en el contexto de programas de elementos finitos, dando como resultado predicciones mas precisas de los procesos de conformado y deformacion plastica en general. Para lograr este objetivo se han desarrollado diversas tareas destinadas a mejorar las predicciones en tres aspectos fundamentales. El primer aspecto consiste en la mejora de la descripcion del endurecimiento cinematico anisotropo en pequenas deformaciones, lo cual se ha realizado a traves de modelos y algoritmos implicitos de superficies multiples. Ha sido estudiada la consistencia de este tipo de modelos tanto si estan basados en una regla implicita similar a la de Mroz o en la regla de Prager. Ademas se han simulado los ensayos de Lamba y Sidebottom, obteniendo, en contra de la creencia general, muy buenas predicciones con la regla de Prager. Dichos modelos podrian ser extendidos de forma relativamente facil para considerar grandes deformaciones a traves de procedimientos en deformaciones logaritmicas, similares a los desarrollados en esta tesis y detallados a continuacion. El segundo aspecto consiste en la descripcion de la anisotropia elastoplastica inicial. Esto se ha conseguido mediante el desarrollo de modelos y algoritmos para plasticidad anisotropa en grandes deformaciones, bien ignorando la posible anisotropia elastica, bien considerandola simultaneamente con la anisotropia plastica. Para ello ha sido necesario desarrollar primero un nuevo algoritmo de elastoplasticidad anisotropa en pequenas deformaciones consistentemente linealizado y sin despreciar ningun termino, de tal forma que se conserve la convergencia cuadratica de los metodos de Newton. Este algoritmo en pequenas deformaciones ha servido para realizar la correccion plastica de dos algoritmos en grandes deformaciones. El primero de estos algoritmos es una variacion del clasico algoritmo de

Microenvironmental agonists generate de novo phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL.

PubMed

Jayappa, Kallesh D; Portell, Craig A; Gordon, Vicki L; Capaldo, Brian J; Bekiranov, Stefan; Axelrod, Mark J; Brett, L Kyle; Wulfkuhle, Julia D; Gallagher, Rosa I; Petricoin, Emanuel F; Bender, Timothy P; Williams, Michael E; Weber, Michael J

2017-06-13

De novo resistance and rapid recurrence often characterize responses of B-cell malignancies to ibrutinib (IBR), indicating a need to develop drug combinations that block compensatory survival signaling and give deeper, more durable responses. To identify such combinations, we previously performed a combinatorial drug screen and identified the Bcl-2 inhibitor venetoclax (VEN) as a promising partner for combination with IBR in Mantle Cell Lymphoma (MCL). We have opened a multi-institutional clinical trial to test this combination. However, analysis of primary samples from patients with MCL as well as chronic lymphocytic leukemia (CLL) revealed unexpected heterogeneous de novo resistance even to the IBR+VEN combination. In the current study, we demonstrate that resistance to the combination can be generated by microenvironmental agonists: IL-10, CD40L and, most potently, CpG-oligodeoxynucleotides (CpG-ODN), which is a surrogate for unmethylated DNA and a specific agonist for TLR9 signaling. Incubation with these agonists caused robust activation of NF-κB signaling, especially alternative NF-κB, which led to enhanced expression of the anti-apoptotic proteins Mcl-1, Bcl-xL, and survivin, thus decreasing dependence on Bcl-2. Inhibitors of NF-κB signaling blocked overexpression of these anti-apoptotic proteins and overcame resistance. Inhibitors of Mcl-1, Bcl-xL, or survivin also overcame this resistance, and showed synergistic benefit with the IBR+VEN combination. We conclude that microenvironmental factors, particularly the TLR9 agonist, can generate de novo resistance to the IBR+VEN combination in CLL and MCL cells. This signaling pathway presents targets for overcoming drug resistance induced by extrinsic microenvironmental factors in diverse B-cell malignancies.

The power of instructions: Proactive configuration of stimulus-response translation.

PubMed

Meiran, Nachshon; Pereg, Maayan; Kessler, Yoav; Cole, Michael W; Braver, Todd S

2015-05-01

Humans are characterized by an especially highly developed ability to use instructions to prepare toward upcoming events; yet, it is unclear just how powerful instructions can be. Although prior work provides evidence that instructions can be sufficiently powerful to proactively program working memory to execute stimulus-response (S-R) translations, in a reflexlike fashion (intention-based reflexivity [IBR]), the results to date have been equivocal. To overcome this shortcoming, we developed, and tested in 4 studies, a novel paradigm (the NEXT paradigm) that isolates IBR effects even prior to first task execution. In each miniblock, participants received S-R mapping instructions for a new task. Prior to implementing this mapping, responses were required to advance through screens during a preparatory (NEXT) phase. When the NEXT response was incompatible with the instructed S-R mapping, interference (IBR effect) was observed. This NEXT compatibility effect and performance in the implementation (GO) trials barely changed when prior practice of a few trials was provided. Finally, a manipulation that encouraged preparation resulted in relatively durable NEXT compatibility effects (indicating durable preparatory efforts) coupled with improved GO performance (indicating the success of these efforts). Together, these findings establish IBR as a marker of instructed proactive control. (c) 2015 APA, all rights reserved).

Effects of supplemental chromium on antibody responses of newly weaned feedlot calves to immunization with infectious bovine rhinotracheitis and parainfluenza 3 virus.

PubMed Central

Burton, J L; Mallard, B A; Mowat, D N

1994-01-01

The objective of this study was to determine the effect of supplemental dietary chromium (Cr) on antibody responses of feedlot calves. Fifty-five newly weaned calves were divided into two groups, 28 that received supplemental Cr and 27 that did not, and were immunized with a commercial vaccine against bovine infectious rhinotracheitis virus (IBR) and bovine parainfluenza virus type 3(PI-3). Sera harvested from blood sampled preimmunization, and at days 14 and 28 postimmunization (PI), were assayed for anti-IBR and anti-PI-3 antibody titers. Individual calves were also scored as seroconverters if day 14 or 28 PI titers were > or = 3 times the value of the preimmunization titer. Thirty-five calves did not seroconvert to either antigen. Of 20 IBR seroconverters, 15 calves were from the Cr-supplemented group while only five calves were controls (p = 0.007). There was no treatment difference in the number of PI-3 seroconverters. Least squares analysis of actual antibody titers revealed that Cr supplementation increased the magnitude of the peak antibody response to the IBR (p = 0.003), but had no effect on anti-PI-3 antibody titers. These data confirmed and extended our previous observations that supplemental Cr can be immunomodulatory in cattle. PMID:8004541

Estudio de la formación de galaxias espirales en un modelo de agregación jerárquica

NASA Astrophysics Data System (ADS)

Tissera, P.; Saiz, A.; Dominguez-Tenreiro, R.

El estudio de formación de galaxias espirales ha llevado al desarrollo de numerosos modelos teóricos (e.g. White & Rees 1978). En la actualidad, el modelo más aceptado predice la formación de una galaxia espiral a partir del colapso disipativo del gas en el pozo de potencial de un halo oscuro, conservando su momento angular específco (Fall & Efstathiou 1980). En los últimos años, ha sido posible realizar simulaciones numéricas hidrodinámicas, las cuales describen la evolución conjunta de la materia oscura y los bariones. Estos experimentos han señalado la dificultad de formar estructuras discoidales con propiedades consistentes con las observaciones, en modelos de agregación jerárquica. El problema principal se origina en la pérdida catastrófica de momento angular de la componente disipativa, durante el proceso de ensamblaje de los objetos, a través de la fusión de subestructura (Navarro & Steinmetz 1997). Estos experimentos no incluían procesos de formación estelar. En este trabajo, se expondrán resultados de simulaciones hidrodinámicas cosmológicas, incluyendo formación estelar (Tissera et al 1997), donde ha sido posible reproducir objetos discoidales con contrapartida observacional. El elemento fundamental ha sido la formación de bulbos estelares, los cuales han evitado la pérdida catastrófica de momento angular de los bariones. Se encontró que los discos exponenciales puramente gaseosos son altamente inestables y suceptibles de generar barras, responsables de la pérdida de momento angular y la caída violenta del gas hacia la región central. Estas inestabilidades son fácilmente inducidas durante interacciones y fusiones con objetos vecinos (Barnes & Hernquist 1996). Un bulbo estelar (o un objeto masivo y compacto) estabiliza el disco ante perturbaciones externas, asegurándole un potencial simétrico (Sellwood & Moore 1998, Van der Bosch 1998). En este caso, el gas en el disco no pierde completamente su momento angular intr

Toward Advanced Nursing Practice along with People-Centered Care Partnership Model for Sustainable Universal Health Coverage and Universal Access to Health.

PubMed

Kamei, Tomoko; Takahashi, Keiko; Omori, Junko; Arimori, Naoko; Hishinuma, Michiko; Asahara, Kiyomi; Shimpuku, Yoko; Ohashi, Kumiko; Tashiro, Junko

2017-01-30

this study developed a people-centered care (PCC) partnership model for the aging society to address the challenges of social changes affecting people's health and the new role of advanced practice nurses to sustain universal health coverage. a people-centered care partnership model was developed on the basis of qualitative meta-synthesis of the literature and assessment of 14 related projects. The ongoing projects resulted in individual and social transformation by improving community health literacy and behaviors using people-centered care and enhancing partnership between healthcare providers and community members through advanced practice nurses. people-centered care starts when community members and healthcare providers foreground health and social issues among community members and families. This model tackles these issues, creating new values concerning health and forming a social system that improves quality of life and social support to sustain universal health care through the process of building partnership with communities. a PCC partnership model addresses the challenges of social changes affecting general health and the new role of advanced practice nurses in sustaining UHC. o estudo desenvolveu um modelo de parceria de cuidados centrados nas pessoas (CCP) para uma sociedade que está envelhecendo, com o fim de enfrentar os desafios das mudanças sociais que afetam a saúde das pessoas e o novo papel da prática avançada de enfermagem para sustentar a cobertura universal de saúde. um modelo de parceria de cuidados centrados nas pessoas foi desenvolvido com base na meta-síntese qualitativa da literatura e a avaliação de 14 projetos relacionados. Os projetos em curso resultaram na transformação individual e social, melhorando a alfabetização de saúde da comunidade e comportamentos que usam o cuidado centrado nas pessoas e aumentando a parceria entre os profissionais de saúde e membros da comunidade por meio da prática avançada de enfermagem

Long-Term Update of NRG Oncology RTOG 0319: A Phase 1 and 2 Trial to Evaluate 3-Dimensional Conformal Radiation Therapy Confined to the Region of the Lumpectomy Cavity for Stage I and II Breast Carcinoma

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rabinovitch, Rachel, E-mail: rachel.rabinovitch@ucdenver.edu; Moughan, Jennifer; Vicini, Frank

Purpose: NRG Oncology RTOG 0319 was the first cooperative group trial in the United States to evaluate 3-dimensional conformal radiation therapy (3D-CRT) accelerated partial breast irradiation (APBI). This report updates secondary endpoints of toxicity and efficacy. Methods and Materials: Patients with stage I or II invasive breast cancer (tumor size ≤3 cm, ≤3 positive lymph nodes, negative margins) were eligible for 3D-CRT APBI: 38.5 Gy in 10 twice-daily fractions. Patient characteristics and treatment details have previously been reported. Adverse events were graded with CTCAE v3.0 (National Cancer Institute Common Terminology Criteria for Adverse Events version 3.0). This analysis updates the rates of ipsilateral breastmore » recurrence (IBR), contralateral breast recurrence, ipsilateral node recurrence (INR), metastatic sites (distant metastases [DM]), mastectomy, disease-free survival, mastectomy-free survival, and overall survival. Results: Of 58 enrolled patients, 52 were eligible, with a median age of 61 years; 94% had stage I cancer and 83% had estrogen receptor positive disease. The median follow-up period was 8 years (minimum-maximum, 1.7-9.0 years). The 7-year estimate of isolated IBR (no DM) was 5.9%. The 7-year estimates of all IBRs, INR, mastectomy rate, and DM were 7.7%, 5.8%, 7.7%, and 7.7%, respectively. All 4 IBRs were invasive, of which 3 had a component within the planning target volume. The patterns of failure were as follows: 3 IBRs, 1 INR, 2 DM, 1 INR plus DM, and 1 IBR plus INR plus DM. The 7-year estimates of mastectomy-free survival, disease-free survival, and overall survival were 71.2%, 71.2%, and 78.8%, respectively. Thirteen patients died: 3 of breast cancer and 10 of other causes. Grade 3 (G3) treatment-related adverse events were reported by 4 patients (7.7%). No G3 pain or pulmonary or cardiac toxicities were reported. Conclusions: This phase 1 and 2 trial of 3D-CRT APBI continues to show durable tumor control and

Long-Term Update of NRG Oncology RTOG 0319: A Phase 1 and 2 Trial to Evaluate 3-Dimensional Conformal Radiation Therapy Confined to the Region of the Lumpectomy Cavity for Stage I and II Breast Carcinoma.

PubMed

Rabinovitch, Rachel; Moughan, Jennifer; Vicini, Frank; Pass, Helen; Wong, John; Chafe, Susan; Petersen, Ivy; Arthur, Douglas W; White, Julia

2016-12-01

NRG Oncology RTOG 0319 was the first cooperative group trial in the United States to evaluate 3-dimensional conformal radiation therapy (3D-CRT) accelerated partial breast irradiation (APBI). This report updates secondary endpoints of toxicity and efficacy. Patients with stage I or II invasive breast cancer (tumor size ≤3 cm, ≤3 positive lymph nodes, negative margins) were eligible for 3D-CRT APBI: 38.5 Gy in 10 twice-daily fractions. Patient characteristics and treatment details have previously been reported. Adverse events were graded with CTCAE v3.0 (National Cancer Institute Common Terminology Criteria for Adverse Events version 3.0). This analysis updates the rates of ipsilateral breast recurrence (IBR), contralateral breast recurrence, ipsilateral node recurrence (INR), metastatic sites (distant metastases [DM]), mastectomy, disease-free survival, mastectomy-free survival, and overall survival. Of 58 enrolled patients, 52 were eligible, with a median age of 61 years; 94% had stage I cancer and 83% had estrogen receptor positive disease. The median follow-up period was 8 years (minimum-maximum, 1.7-9.0 years). The 7-year estimate of isolated IBR (no DM) was 5.9%. The 7-year estimates of all IBRs, INR, mastectomy rate, and DM were 7.7%, 5.8%, 7.7%, and 7.7%, respectively. All 4 IBRs were invasive, of which 3 had a component within the planning target volume. The patterns of failure were as follows: 3 IBRs, 1 INR, 2 DM, 1 INR plus DM, and 1 IBR plus INR plus DM. The 7-year estimates of mastectomy-free survival, disease-free survival, and overall survival were 71.2%, 71.2%, and 78.8%, respectively. Thirteen patients died: 3 of breast cancer and 10 of other causes. Grade 3 (G3) treatment-related adverse events were reported by 4 patients (7.7%). No G3 pain or pulmonary or cardiac toxicities were reported. This phase 1 and 2 trial of 3D-CRT APBI continues to show durable tumor control and minimal G3 toxicity, comparable to other APBI techniques. Mature

Transferências orbitais dentro do modelo quase bicircular no sistema Terra-Lua-Sol

NASA Astrophysics Data System (ADS)

Corrêa, A. A.; de Almeida Prado, A. F. B.; Stuchi, T. J.; Beaugé, C.

2003-08-01

O problema quase bicircular planar consiste na determinação da dinâmica de um corpo, de massa desprezível, que se move sob o campo gravitacional de três corpos. No caso estudado, o quarto corpo é considerado um satélite artificial e os demais são a Terra, a Lua e o Sol, formando o sistema de três corpos. Este modelo permite a construção de uma hamiltoniana similar a do problema restrito de três corpos (PRTC), incluindo termos periódicos não autônomos, provenientes da presença do Sol, portanto pode ser entendido como uma perturbação ao PRTC. Suas órbitas periódicas aparecem isoladas e possuem o mesmo período solar. Os pontos de equilíbrio colineares possuem o mesmo caráter de estabilidade linear dos pontos lagrangianos (L1, L2 e L3) do PRTC, sendo do tipo sela x centro x centro, instável na direção x e estáveis nas direções y e z. As órbitas periódicas tridimensionais ao redor do ponto colinear é chamada órbita Halo. O objetivo deste trabalho é determinar órbitas de transferências de baixo consumo de combustível para um veículo espacial partindo de uma órbita de estacionamento ao redor da Terra em direção a uma órbita Halo do ponto L1, situado entre a Terra e Lua. Esta tarefa pode ser transformada no problema de valor de contorno: dado um ponto inicial na órbita de estacionamento, um ponto final na órbita halo e o tempo de transferência, deseja-se obter a trajetória que liga estes dois pontos e que minimize os incrementos de velocidade do veículo. Essas transferências são realizadas baseadas no método de Lambert e analisadas de modo a fornecer um baixo consumo. Posteriormente, é feita uma comparação de consumo com as órbitas de transferência equivalentes do PRTC.

Life-cycle optimization model for distributed generation in buildings

NASA Astrophysics Data System (ADS)

Safaei, Amir

O setor da construcao e responsavel por uma grande parte do consumo de energia e emissoes na Uniao Europeia. A Geracao Distribuida (GD) de energia, nomeadamente atraves de sistemas de cogeracao e tecnologias solares, representa um papel importante no futuro energetico deste setor. A otimizacao do funcionamento dos sistemas de cogeracao e uma tarefa complexa, devido as diversas variaveis em jogo, designadamente: os diferentes tipos de necessidades energeticas (eletricidade, aquecimento e arrefecimento), os precos dinamicos dos combustiveis (gas natural) e da eletricidade, e os custos fixos e variaveis dos diferentes sistemas de GD. Tal torna-se mais complexo considerando a natureza flutuante das tecnologias solares termicas e fotovoltaicas. Ao mesmo tempo, a liberalizacao do mercado da eletricidade permite exportar para a rede, a electricidade gerada localmente. Adicionalmente, a operacao estrategica de um sistema de GD deve atender aos quadros politicos nacionais, se tiver como objetivo beneficiar de tais regimes. Alem disso, considerando os elevados impactes ambientais do setor da construcao, qualquer avaliacao energetica de edificios rigorosa deve tambem integrar aspetos ambientais, utilizando uma abordagem de Ciclo de Vida (CV). Uma avaliacao de Ciclo de Vida (ACV) completa de um sistema de GD deve incluir as fases relativas a operacao e construcao do sistema, bem como os impactes associados a producao dos combustiveis. Foram analisadas as emissoes da producao de GN, as quais variam de acordo com a origem, tipo (convencional ou nao-convencional), e estado (na forma de GN Liquefeito (GNL) ou gas). Do mesmo modo, o impacte dos sistemas solares e afetado pela meteorologia e radiacao solar, de acordo com a sua localizacao geografica. Sendo assim, uma avaliacao adequada dos sistemas de GD exige um modelo de ACV adequado a localizacao geografica (Portugal), integrando tambem a producao de combustivel (GN), tendo em conta as suas diferentes fontes de abastecimento. O

Mixo-IBR BP1A Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ahrens, Toby; Van der Meulen, Leslie

The objective of the initial budget period was to determine whether BioProcess Algae (BPA) had all of the data, information, facilities, and agreements presented in its proposal response to DE-FOA-0000739. BPA was to demonstrate heterotrophic lipid production, demonstrate the production of fuels by metathesis of algal oils, and develop data to justify the scale-up effort proposed for the Pilot Mixotrophic Algae Integrated Biorefinery.

Transient isomers in the photodissociation of bromoiodomethane

NASA Astrophysics Data System (ADS)

Marcellini, Moreno; Nasedkin, Alexandr; Zietz, Burkhard; Petersson, Jonas; Vincent, Jonathan; Palazzetti, Federico; Malmerberg, Erik; Kong, Qingyu; Wulff, Michael; van der Spoel, David; Neutze, Richard; Davidsson, Jan

2018-04-01

The photochemistry of halomethanes is fascinating for the complex cascade reactions toward either the parent or newly synthesized molecules. Here, we address the structural rearrangement of photodissociated CH2IBr in methanol and cyclohexane, probed by time-resolved X-ray scattering in liquid solution. Upon selective laser cleavage of the C-I bond, we follow the reaction cascade of the two geminate geometrical isomers, CH2I-Br and CH2Br-I. Both meta-stable isomers decay on different time scales, mediated by solvent interaction, toward the original parent molecule. We observe the internal rearrangement of CH2Br-I to CH2I-Br in cyclohexane by extending the time window up to 3 μs. We track the photoproduct kinetics of CH2Br-I in methanol solution where only one isomer is observed. The effect of the polarity of solvent on the geminate recombination pathways is discussed.

Subclinical breakdown with infectious bovine rhinotracheitis virus infection in dairy herd of high health status.

PubMed

Pritchard, G C; Banks, M; Vernon, R E

2003-07-26

Infectious bovine rhinotracheitis (IBR) virus infection was detected by an antibody ELISA in the bulk milk of a large closed dairy herd of high health status in an area of low cattle density in East Anglia. The herd was managed under high standards of biosecurity and was known to have been serologically free of IBR virus for the previous 13 years. Although over 70 per cent of the cows had seroconverted to IBR virus no clinical signs were observed apart from a slight bilateral watery ocular discharge in a few cows, and their performance and productivity were unaffected. The causal virus, which was isolated after it had been reactivated with corticosteroid, had the DNA profile of a bovine herpesvirus type 1 strain normally associated with clinically severe respiratory disease. In spite of extensive enquiries and seroepidemiological investigations the source of the infection was not determined.

Microenvironmental agonists generate de novo phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL

PubMed Central

Portell, Craig A.; Gordon, Vicki L.; Capaldo, Brian J.; Bekiranov, Stefan; Axelrod, Mark J.; Brett, L. Kyle; Wulfkuhle, Julia D.; Gallagher, Rosa I.; Petricoin, Emanuel F.; Bender, Timothy P.; Williams, Michael E.

2017-01-01

De novo resistance and rapid recurrence often characterize responses of B-cell malignancies to ibrutinib (IBR), indicating a need to develop drug combinations that block compensatory survival signaling and give deeper, more durable responses. To identify such combinations, we previously performed a combinatorial drug screen and identified the Bcl-2 inhibitor venetoclax (VEN) as a promising partner for combination with IBR in mantle cell lymphoma (MCL). We have opened a multi-institutional clinical trial to test this combination. However, analysis of primary samples from patients with MCL as well as chronic lymphocytic leukemia (CLL) revealed unexpected heterogeneous de novo resistance even to the IBR+VEN combination. In the current study, we demonstrate that resistance to the combination can be generated by microenvironmental agonists: interleukin-10 (IL-10), CD40L and, most potently, cytosine guanine dinucleotide–oligodeoxynucleotides (CpG-ODNs), which is a surrogate for unmethylated DNA and a specific agonist for Toll-like receptor 9 (TLR9) signaling. Incubation with these agonists caused robust activation of NF-κB signaling, especially alternative NF-κB, which led to enhanced expression of the antiapoptotic proteins Mcl-1, Bcl-xL, and survivin, thus decreasing dependence on Bcl-2. Inhibitors of NF-κB signaling blocked overexpression of these antiapoptotic proteins and overcame resistance. Inhibitors of Mcl-1, Bcl-xL, or survivin also overcame this resistance, and showed synergistic benefit with the IBR+VEN combination. We conclude that microenvironmental factors, particularly the TLR9 agonist, can generate de novo resistance to the IBR+VEN combination in CLL and MCL cells. This signaling pathway presents targets for overcoming drug resistance induced by extrinsic microenvironmental factors in diverse B-cell malignancies. PMID:29034364

Autoreporte de exposición a publicidad y promoción de tabaco en una cohorte de fumadores mexicanos: Antes y durante la publicación de la Ley General para el Control del tabaco en 2008

PubMed Central

Hernández, Rosaura Pérez; Thrasher, James F.; Bolaños, Rosibel Rodríguez; Gutiérrez, Inti Barrientos; Hernández, Norma A Ibañez

2015-01-01

Resumen Objetivo Determinar en población fumadora el nivel de exposición a la mercadotecnia por parte de la Industria Tabacalera (IT), a través de diferentes métodos de promocionar sus productos de tabaco, antes y durante la publicación de la Ley General para el Control del Tabaco (LGCT) en 2008. Material y métodos Estudio de cohorte en fumadores adultos (n=941 pre-LGCT y n=1051 post-LGCT) de cuatro ciudades mexicanas. Se realizaron análisis multivariados mediante modelos de ecuaciones de estimación generalizada (GEE). Resultados Se incremento el autoreporte de recepción de muestras gratis de cigarros (3.7% a 8.1%), ropa o artículos con marcas o logos (3.6% a 6.4%), haber visto información sobre eventos especiales (1.9% a 4.7%), y bares, antros y discos para mayores de edad (21.4% a 28%). Se observaron decrementos de publicidad en exteriores (54.7% a 47.2%). Conclusión Es necesaria una política integral con prohibiciones totales de la publicidad y promoción de los productos de tabaco que integre mayor vigilancia y sanciones para lograr la disminución y prevención del consumo de tabaco. PMID:22689158

Memorias del tercer simposio internacional sobre economía, planificación, y políticas de los incendios forestales: problemas y enfoques comunes

Treesearch

Armando González-Cabán

2009-01-01

Estas memorias resumen el resultado de un simposio diseñado para discutir los problemas actuales que confrontan las agencias con responsabilidad para la proteccion contra incendios forestales a nivel federal y estadual en los EE.UU., al igual que agencias en la comunidad internacional. Los temas discutidos en el simposio incluyen economía del fuego, teoría y modelos...

Superoxide reaction with tyrosyl radicals generates para-hydroperoxy and para-hydroxy derivatives of tyrosine.

PubMed

Möller, Matías N; Hatch, Duane M; Kim, Hye-Young H; Porter, Ned A

2012-10-10

Tyrosine-derived hydroperoxides are formed in peptides and proteins exposed to enzymatic or cellular sources of superoxide and oxidizing species as a result of the nearly diffusion-limited reaction between tyrosyl radical and superoxide. However, the structure of these products, which informs their reactivity in biology, has not been unequivocally established. We report here the complete characterization of the products formed in the addition of superoxide, generated from xanthine oxidase, to several peptide-derived tyrosyl radicals, formed from horseradish peroxidase. RP-HPLC, LC-MS, and NMR experiments indicate that the primary stable products of superoxide addition to tyrosyl radical are para-hydroperoxide derivatives (para relative to the position of the OH in tyrosine) that can be reduced to the corresponding para-alcohol. In the case of glycyl-tyrosine, a stable 3-(1-hydroperoxy-4-oxocyclohexa-2,5-dien-1-yl)-L-alanine was formed. In tyrosyl-glycine and Leu-enkephalin, which have N-terminal tyrosines, bicyclic indolic para-hydroperoxide derivatives were formed ((2S,3aR,7aR)-3a-hydroperoxy-6-oxo-2,3,3a,6,7,7a-hexahydro-1H-indole-2-carboxylic acid) by the conjugate addition of the free amine to the cyclohexadienone. It was also found that significant amounts of the para-OH derivative were generated from the hydroxyl radical, formed on exposure of tyrosine-containing peptides to Fenton conditions. The para-OOH and para-OH derivatives are much more reactive than other tyrosine oxidation products and may play important roles in physiology and disease.

Compilação de dados atômicos e moleculares do UV ao IV próximo para uso em síntese espectral

NASA Astrophysics Data System (ADS)

Coelho, P.; Barbuy, B.; Melendez, J.; Allen, D. M.; Castilho, B.

2003-08-01

Espectros sintéticos são utéis em uma grande variedade de aplicações, desde análise de abundâncias em espectros estelares de alta resolução ao estudo de populações estelares em espectros integrados. A confiabilidade de um espectro sintético depende do modelo de atmosfera adotado, do código de formação de linhas e da qualidade dos dados atômicos e moleculares que são determinantes no cálculo das opacidades da fotosfera. O nosso grupo no departamento de Astronomia no IAG tem utilizado espectros sintéticos há mais de 15 anos, em aplicações voltadas principalmente para a análise de abundâncias de estrelas G, K e M e populações estelares velhas. Ao longo desse tempo, as listas de linhas vieram sendo construídas e atualizadas continuamente, e alguns acréscimos recentes podem ser citados: Castilho (1999, átomos e moléculas no UV), Schiavon (1998, bandas moleculares de TiO) e Melendez (2001, átomos e moléculas no IV próximo). Com o intuito de calcular uma grade de espectros do UV ao IV próximo para uso no estudo de populações estelares velhas, se fazia necessário compilar e homogeneizar as diversas listas em apenas uma lista atômica e uma molecular. Nesse processo, a nova lista compilada foi correlacionada com outras bases de dados (NIST, Kurucz Database, O' Brian et al. 1991) para atualização dos parâmetros que caracterizam a transição atômica (comprimento de onda, log gf e potencial de excitação). Adicionalmente as constantes de interação C6 foram calculadas segundo a teoria de Anstee & O'Mara (1995) e artigos posteriores. As bandas moleculares de CH e CN foram recalculadas com o programa LIFBASE (Luque & Crosley 1999). Nesse poster estão detalhados os procedimentos citados acima, as comparações entre espectros calculados com as novas listas e espectros observados em alta resolução do Sol e de Arcturus, e uma análise do impacto decorrente da utilização de diferentes modelos de atmosfera no espectro sintético. Ao

Determining bovine viral diarrhea and infectious bovine rhinotracheitis infections in dairy cattle using precolostral blood.

PubMed

Baillargeon, Paul; Arango-Sabogal, Juan C; Wellemans, Vincent; Fecteau, Gilles

2017-04-01

The objective of this study was to determine if precolostral blood samples are useful to detect apparent fetal infections with bovine viral diarrhea (BVD) and infectious bovine rhinotracheitis (IBR) viruses. A convenience sample of 317 sera from 50 Canadian herds was used in the study. Antibody level was measured using 2 commercial IBR and BVD ELISA kits. Precolostral status of sera was confirmed on 304 samples using serum gamma-glutamyl transferase activity. Postcolostral serum samples yielded a higher proportion of positive results to IBR (OR = 86; 95% CI: 17.8 to 415.7) and BVD (OR = 199.3; 95% CI: 41.7 to 952.3) than did precolostral samples. All positive precolostral serum samples ( n = 7 of 304) originated from calves born to vaccinated cows. Postcolostral positive serum samples ( n = 11 of 13) originated mostly (60%) from calves born to non-vaccinated cows. Precolostral serum sampling can detect apparent fetal infections in a herd.

Memorias del segundo simposio internacional sobre políticas, planificación y economía de los programas de protección contra incendios forestales: una visión global; 2004 Abril 19–22; Córdoba, España

Treesearch

Armando González-Cabán

2008-01-01

Estas memorias resumen el resultado de un simposio diseñado para discutir los problemas actuales que confrontan las agencias con responsabilidad para la protección contra incendios forestales a nivel federal y estadual en los EE.UU., al igual que agencias en la comunidad internacional. Los temas discutidos en el simposio incluyen economía del fuego, teoría y modelos...

Recovery Act. Demonstration of a Pilot Integrated Biorefinery for the Efficient, Direct Conversion of Biomass to Diesel Fuel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schuetzle, Dennis; Tamblyn, Greg; Caldwell, Matt

2015-05-12

The Renewable Energy Institute International, in collaboration with Greyrock Energy and Red Lion Bio-Energy (RLB) has successfully demonstrated operation of a 25 ton per day (tpd) nameplate capacity, pilot, pre-commercial-scale integrated biorefinery (IBR) plant for the direct production of premium, “drop-in”, synthetic fuels from agriculture and forest waste feedstocks using next-generation thermochemical and catalytic conversion technologies. The IBR plant was built and tested at the Energy Center, which is located in the University of Toledo Medical Campus in Toledo, Ohio.

Fuzzy model to estimate the number of hospitalizations for asthma and pneumonia under the effects of air pollution.

PubMed

Chaves, Luciano Eustáquio; Nascimento, Luiz Fernando Costa; Rizol, Paloma Maria Silva Rocha

2017-06-22

Predict the number of hospitalizations for asthma and pneumonia associated with exposure to air pollutants in the city of São José dos Campos, São Paulo State. This is a computational model using fuzzy logic based on Mamdani's inference method. For the fuzzification of the input variables of particulate matter, ozone, sulfur dioxide and apparent temperature, we considered two relevancy functions for each variable with the linguistic approach: good and bad. For the output variable number of hospitalizations for asthma and pneumonia, we considered five relevancy functions: very low, low, medium, high and very high. DATASUS was our source for the number of hospitalizations in the year 2007 and the result provided by the model was correlated with the actual data of hospitalization with lag from zero to two days. The accuracy of the model was estimated by the ROC curve for each pollutant and in those lags. In the year of 2007, 1,710 hospitalizations by pneumonia and asthma were recorded in São José dos Campos, State of São Paulo, with a daily average of 4.9 hospitalizations (SD = 2.9). The model output data showed positive and significant correlation (r = 0.38) with the actual data; the accuracies evaluated for the model were higher for sulfur dioxide in lag 0 and 2 and for particulate matter in lag 1. Fuzzy modeling proved accurate for the pollutant exposure effects and hospitalization for pneumonia and asthma approach. Prever o número de internações por asma e pneumonia associadas à exposição a poluentes do ar no município em São José dos Campos, estado de São Paulo. Trata-se de um modelo computacional que utiliza a lógica fuzzy baseado na técnica de inferência de Mamdani. Para a fuzzificação das variáveis de entrada material particulado, ozônio, dióxido de enxofre e temperatura aparente foram consideradas duas funções de pertinência para cada variável com abordagem linguísticas: bom e ruim. Para a variável de saída número interna

Study and optimization of the macroscopic electrical response of carbon based nanocomposites for advanced applications

NASA Astrophysics Data System (ADS)

Silva, Jaime Pedro Oliveira da

A presente tese centrou-se no estudo da resposta da constante dieletrica e condutividade eletrica em materiais compositos nos quais o reforco tinha uma elevada proporcao entre comprimento e diametro. O objeto de estudo foi o efeito de um reforco com uma elevada razao entre comprimento e diametro, concentracao e orientacao na resposta eletrica e dieletrica de um composito. Estes compositos tem uma grande importancia no desenvolvimento de materiais para sensores e atuadores. Num primeiro momento da dissertacao, explorou-se a resposta da constante dieletrica de um composito constituido por nanotubos de carbono como reforco e uma matriz polimerica. Verificou-se que um aumento da razao entre comprimento e diametro do reforco tem o efeito de aumentar a constante dieletrica do composito para uma igual fracao volumetrica de reforco. Constatou-se tambem que materiais na fase nematica demonstram uma constante dieletrica mais baixa quando comparados com materiais onde o reforco esta distribuido aleatoriamente. Ficou ainda demonstrado nesta dissertacao que materiais na fase nematica com razoes entre o comprimento e diametro diferentes a constante dieletrica segue uma lei de potencia. Numa segunda fase do trabalho, foi explorada a condutividade de nanocompositos polimericos reforcados com nanotubos de carbono, atraves de um modelo baseado em cilindros impenetraveis. Ficou demonstrado que o modelo e apropriado para descrever a condutividade eletrica de um nanocomposito polimerico reforcado com nanotubos. As simulacoes desenvolvidas demonstram que, aumentando a razao entre o comprimento e o diametro dos nanotubos de carbono, aumenta a condutividade eletrica do nanocomposito. No entanto, verifica-se que aumentando a anisotropia diminui a condutividade, sendo este efeito mais evidente para fracoes volumetricas maiores. Nesta dissertacao comprovou-se ainda que uma microestrutura gerada por um algoritmo de empacotamento sequencial pode ser descrita por um grafo aleatorio e que a

Producing and quantifying enriched para-H2.

PubMed

Tom, Brian A; Bhasker, Siddhartha; Miyamoto, Yuki; Momose, Takamasa; McCall, Benjamin J

2009-01-01

The production of enriched para-H(2) is useful for many scientific applications, but the technology for producing and measuring para-H(2) is not yet widespread. In this note and in the accompanying auxiliary material, we describe the design, construction, and use of a versatile standalone converter that is capable of producing para-H(2) enrichments of up to > or = 99.99% at continuous flow rates of up to 0.4 SLM. We also discuss para-H(2) storage and back conversion rates, and improvements to three techniques (thermal conductance, NMR, and solid hydrogen impurity spectroscopy) used to quantify the para-H(2) enrichment.

Long-Term Cancer Outcomes From Study NRG Oncology/RTOG 9517: A Phase 2 Study of Accelerated Partial Breast Irradiation With Multicatheter Brachytherapy After Lumpectomy for Early-Stage Breast Cancer

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, Julia, E-mail: Julia.White@osumc.edu; Winter, Kathryn; Kuske, Robert R.

Purpose: To examine 10-year rates of local, regional, and distant recurrences, patterns of recurrence, and survival rates for breast cancer patients enrolled on Study NRG Oncology/Radiation Therapy Oncology Group 9517, a multi-institutional prospective trial that studied one of the earliest methods of accelerated partial breast irradiation (APBI), multicatheter brachytherapy (MCT). Methods and Materials: Eligibility included stage I/II unifocal breast cancer <3 cm in size after lumpectomy with negative surgical margins and 0 to 3 positive axillary nodes without extracapsular extension. The APBI dose delivered was 34 Gy in 10 twice-daily fractions over 5 days for high-dose-rate (HDR); and 45 Gy in 3.5 to 5 days formore » low-dose-rate (LDR) brachytherapy. The primary endpoint was HDR and LDR MCT reproducibility. This analysis focuses on long-term ipsilateral breast recurrence (IBR), contralateral breast cancer events (CBE), regional recurrence (RR), and distant metastases (DM), disease-free, and overall survival. Results: The median follow-up was 12.1 years. One hundred patients were accrued from 1997 to 2000; 98 were evaluable; 65 underwent HDR and 33 LDR MCT. Median age was 62 years; 88% had T1 tumors; 81% were pN0. Seventy-seven percent were estrogen receptor and/or progesterone receptor positive; 33% received adjuvant chemotherapy and 64% antiendocrine therapy. There have been 4 isolated IBRs and 1 IBR with RR, for 5.2% 10-year IBR without DM. There was 1 isolated RR, 1 with IBR, and 1 with a CBE, for 3.1% 10-year RR without DM. The 10-year CBE rate was 4.2%, with 5 total events. Eleven patients have developed DM, 8 have died of breast cancer, and 22 have died from other causes. The 10-year DFS and OS rates are 69.8% and 78.0%, respectively. Conclusion: This multi-institutional, phase 2 trial studying MCT-APBI continues to report durable in-breast cancer control rates with long-term follow-up.« less

Long-Term Cancer Outcomes From Study NRG Oncology/RTOG 9517: A Phase 2 Study of Accelerated Partial Breast Irradiation With Multicatheter Brachytherapy After Lumpectomy for Early-Stage Breast Cancer.

PubMed

White, Julia; Winter, Kathryn; Kuske, Robert R; Bolton, John S; Arthur, Douglas W; Scroggins, Troy; Rabinovitch, Rachel A; Kelly, Tracy; Toonkel, Leonard M; Vicini, Frank A; McCormick, Beryl

2016-08-01

To examine 10-year rates of local, regional, and distant recurrences, patterns of recurrence, and survival rates for breast cancer patients enrolled on Study NRG Oncology/Radiation Therapy Oncology Group 9517, a multi-institutional prospective trial that studied one of the earliest methods of accelerated partial breast irradiation (APBI), multicatheter brachytherapy (MCT). Eligibility included stage I/II unifocal breast cancer <3 cm in size after lumpectomy with negative surgical margins and 0 to 3 positive axillary nodes without extracapsular extension. The APBI dose delivered was 34 Gy in 10 twice-daily fractions over 5 days for high-dose-rate (HDR); and 45 Gy in 3.5 to 5 days for low-dose-rate (LDR) brachytherapy. The primary endpoint was HDR and LDR MCT reproducibility. This analysis focuses on long-term ipsilateral breast recurrence (IBR), contralateral breast cancer events (CBE), regional recurrence (RR), and distant metastases (DM), disease-free, and overall survival. The median follow-up was 12.1 years. One hundred patients were accrued from 1997 to 2000; 98 were evaluable; 65 underwent HDR and 33 LDR MCT. Median age was 62 years; 88% had T1 tumors; 81% were pN0. Seventy-seven percent were estrogen receptor and/or progesterone receptor positive; 33% received adjuvant chemotherapy and 64% antiendocrine therapy. There have been 4 isolated IBRs and 1 IBR with RR, for 5.2% 10-year IBR without DM. There was 1 isolated RR, 1 with IBR, and 1 with a CBE, for 3.1% 10-year RR without DM. The 10-year CBE rate was 4.2%, with 5 total events. Eleven patients have developed DM, 8 have died of breast cancer, and 22 have died from other causes. The 10-year DFS and OS rates are 69.8% and 78.0%, respectively. This multi-institutional, phase 2 trial studying MCT-APBI continues to report durable in-breast cancer control rates with long-term follow-up. Copyright © 2016 Elsevier Inc. All rights reserved.

Ortho-para-hydrogen equilibration on Jupiter

NASA Technical Reports Server (NTRS)

Carlson, Barbara E.; Lacis, Andrew A.; Rossow, William B.

1992-01-01

Voyager IRIS observations reveal that the Jovian para-hydrogen fraction is not in thermodynamic equilibrium near the NH3 cloud top, implying that a vertical gradient exists between the high-temperature equilibrium value of 0.25 at depth and the cloud top values. The height-dependent para-hydrogen profile is obtained using an anisotropic multiple-scattering radiative transfer model. A vertical correlation is found to exist between the location of the para-hydrogen gradient and the NH3 cloud, strongly suggesting that paramagnetic conversion on NH3 cloud particle surfaces is the dominant equilibration mechanism. Below the NH3 cloud layer, the para fraction is constant with depth and equal to the high-temperature equilibrium value of 0.25. The degree of cloud-top equilibration appears to depend on the optical depth of the NH3 cloud layer. Belt-zone variations in the para-hydrogen profile seem to be due to differences in the strength of the vertical mixing.

Ajuste de parámetros libres en teorías de campos camaleones a partir de espectros de nubes moleculares galácticas y experimentos terrestres

NASA Astrophysics Data System (ADS)

Teppa Pannia, F. A.; Landau, S. J.

Resultados recientes, basados en el análisis de espectros moleculares de nubes galácticas a través del método del amoníaco, han arrojado nuevos límites sobre la variación del parámetro adimensional μ=m_e /m_p. Los resultados indican Δ μ/μ = (μ_{obs}-μ_{lab})/μ_{lab}= (2.2± 0.4_{est} ±0.3_{sist}) times 10 ^{-8}, en acuerdo con una variación no nula de dicha cantidad (Levshakov et al. 2010). En este trabajo, motivado por los datos astronómicos, estudiamos la solución lineal del modelo teórico fenomenológico de campo escalar camaleón, presentado por Mota y Shaw (2007), que predice variaciones en μ. Con el fin de cotejar estas predicciones con los resultados observacionales, utilizamos datos de experimentos terrestres que testean violaciones al Principio de Equivalencia para analizar el valor de los parámetros libres presentes en el modelo. El trabajo realizado muestra que la solución estudiada no se puede ajustar a los datos experimentales, sugiriendo que el modelo lineal debe ser descartado para explicar las observaciones astronómicas. FULL TEXT IN SPANISH

Construction and validation of nursing diagnoses for people in palliative care.

PubMed

Silva, Rudval Souza da; Pereira, Álvaro; Nóbrega, Maria Miriam Lima da; Mussi, Fernanda Carneiro

2017-08-03

to construct and validate nursing diagnoses for people in palliative care based on the Dignity-Conserving Care Model and the International Classification for Nursing Practice. a two-stage methodological study: 1) construction of the database of clinically and culturally relevant terms for the nursing care for people in palliative care and 2) construction of nursing diagnoses from the database of terms, based on the guidelines of the International Council of Nurses. the 262 terms validated constituted a database of terms from which 56 nursing diagnoses were developed. Of these, 33 were validated by a group of 26 experts, and classified in the three categories of the Dignity-Conserving Care Model: illness-related concerns (21); dignity-conserving repertoire (9); and social dignity inventory (3). of the 33 validated diagnoses, 18 of them could be included in the update of the Catalog of the International Classification for Nursing Practice - palliative care for a dignified death. The study contributes to support the clinical reasoning and decision making of the nurse. construir e validar diagnósticos de enfermagem para pessoas em cuidados paliativos, fundamentados no Modelo de Cuidados para Preservação da Dignidade e na Classificação Internacional para a Prática de Enfermagem. estudo metodológico operacionalizado em duas etapas: 1) construção do banco de termos relevantes, clínica e culturalmente, para a assistência de enfermagem à pessoa em cuidados paliativos e 2) construção de diagnósticos de enfermagem a partir do banco de termos, com base nas diretrizes do Conselho Internacional de Enfermeiros. os 262 termos validados constituíram um banco de termos a partir do qual foram desenvolvidos 56 diagnósticos de enfermagem. Desses, 33 foram validados por um grupo de 26 peritos, e classificados nas três categorias do Modelo de Cuidados para Preservação da Dignidade: preocupações relacionadas com a doença (21); repertório de conservação da

Tiempo para un cambio

NASA Astrophysics Data System (ADS)

Woltjer, L.

1987-06-01

En la reunion celebrada en diciembre dei ano pasado informe al Consejo de mi deseo de terminar mi contrato como Director General de la ESO una vez que fuera aprobado el proyecto dei VLT, que se espera sucedera hacia fines de este aAo. Cuando fue renovada mi designacion hace tres aAos, el Consejo conocia mi intencion de no completar los cinco aAos dei contrato debido a mi deseo de disponer de mas tiempo para otras actividades. Ahora, una vez terminada la fase preparatoria para el VLT, Y habiendose presentado el proyecto formalmente al Consejo el dia 31 de marzo, y esperando su muy probable aprobacion antes dei termino de este ano, me parece que el 10 de enero de 1988 presenta una excelente fecha para que se produzca un cambio en la administracion de la ESO.

INSTRUMENTS AND METHODS OF INVESTIGATION: Giant pulses of thermal neutrons in large accelerator beam dumps. Possibilities for experiments

NASA Astrophysics Data System (ADS)

Stavissky, Yurii Ya

2006-12-01

A short review is presented of the development in Russia of intense pulsed neutron sources for physical research — the pulsating fast reactors IBR-1, IBR-30, IBR-2 (Joint Institute for Nuclear Research, Dubna), and the neutron-radiation complex of the Moscow meson factory — the 'Troitsk Trinity' (RAS Institute for Nuclear Research, Troitsk, Moscow region). The possibility of generating giant neutron pulses in beam dumps of superhigh energy accelerators is discussed. In particular, the possibility of producing giant pulsed thermal neutron fluxes in modified beam dumps of the large hadron collider (LHD) under construction at CERN is considered. It is shown that in the case of one-turn extraction ov 7-TeV protons accumulated in the LHC main rings on heavy targets with water or zirconium-hydride moderators placed in the front part of the LHC graphite beam-dump blocks, every 10 hours relatively short (from ~100 µs) thermal neutron pulses with a peak flux density of up to ~1020 neutrons cm-2 s-1 may be produced. The possibility of applying such neutron pulses in physical research is discussed.

Have Chinese water pricing reforms reduced urban residential water demand?

NASA Astrophysics Data System (ADS)

Zhang, B.; Fang, K. H.; Baerenklau, K. A.

2017-06-01

China continues to deal with severe levels of water scarcity and water pollution. To help address this situation, the Chinese central government initiated urban water pricing reforms in 2002 that emphasized the adoption of increasing block rate (IBR) price structures in place of existing uniform rate structures. By combining urban water use records with microlevel data from the Chinese Urban Household Survey, this research investigates the effectiveness of this national policy reform. Specifically, we compare household water consumption in 28 cities that adopted IBR pricing structures during 2002-2009, with that of 110 cities that had not yet done so. Based on difference-in-differences models, our results show that the policy reform reduced annual residential water demand by 3-4% in the short run and 5% in the longer run. These relatively modest reductions are consistent with the generous nature of the IBR pricing structures that Chinese cities have typically chosen to implement. Our results imply that more efforts are needed to address China's persistent urban water scarcity challenges.

A chicken influenza virus recognizes fucosylated α2,3 sialoglycan receptors on the epithelial cells lining upper respiratory tracts of chickens.

PubMed

Hiono, Takahiro; Okamatsu, Masatoshi; Nishihara, Shoko; Takase-Yoden, Sayaka; Sakoda, Yoshihiro; Kida, Hiroshi

2014-05-01

Influenza viruses recognize sialoglycans as receptors. Although viruses isolated form chickens preferentially bind to sialic acid α2,3 galactose (SAα2,3Gal) glycans as do those of ducks, chickens were not experimentally infected with viruses isolated from ducks. A chicken influenza virus, A/chicken/Ibaraki/1/2005 (H5N2) (Ck/IBR) bound to fucose-branched SAα2,3Gal glycans, whereas the binding towards linear SAα2,3Gal glycans was weak. On the epithelial cells of the upper respiratory tracts of chickens, fucose-branched SAα2,3Gal glycans were detected, but not linear SAα2,3Gal glycans. The growth of Ck/IBR in MDCK-FUT cells, which were genetically prepared to express fucose-branched SAα2,3Gal glycans, was significantly higher than that in the parental MDCK cells. The present results indicate that fucose-branched SAα2,3Gal glycans existing on the epithelial cells lining the upper respiratory tracts of chickens are critical for recognition by Ck/IBR. Copyright © 2014 Elsevier Inc. All rights reserved.

[Tolerance of latissimus dorsi without implant to radiotherapy in immediate breast reconstruction].

PubMed

Carrabin, N; Vermersh, C; Faure, C; Dammacco, M A; Delay, E; Ho Quoc, C

2015-12-01

Rates of immediate breast reconstruction (IBR) after mastectomy are currently increasing, leading us to evaluate outcomes of breast reconstruction with latissimus dorsi without implant followed by adjuvant radiotherapy. From January 1999 to August 2013, 31 breast reconstructions with latissimus dorsi have been irradiated. Patients have been selected from a prospective database and contacted to evaluate outcomes of breast reconstruction, and 2 patients have been lost. Median follow-up was 6.5 years. Breast reconstruction outcomes were evaluated as very good or good in 86% of cases, with breast reconstructed consistency as very good or good in 93% of cases. An additional fat grafting has been performed for 58% of cases (mean volume transferred of 250 cc) and was associated with contralateral breast reduction in 32% of the whole population. IBR was judged as essential for 79% of women a posteriori. In our experience, latissimus dorsi has a good tolerance to adjuvant irradiation, and may be offered to patients willing to benefit of an IBR even if postoperative radiotherapy is scheduled. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Nonclassical and semiclassical para-Bose states

NASA Astrophysics Data System (ADS)

Huerta Alderete, C.; Villanueva Vergara, Liliana; Rodríguez-Lara, B. M.

2017-04-01

Motivated by the proposal to simulate para-Bose oscillators in a trapped-ion setup [C. Huerta Alderete and B. M. Rodríguez-Lara, Phys. Rev. A 95, 013820 (2017), 10.1103/PhysRevA.95.013820], we introduce an overcomplete, nonorthogonal basis for para-Bose Hilbert spaces. The states spanning these bases can be experimentally realized in the trapped-ion simulation via time evolution. The para-Bose states show both nonclassical and semiclassical statistics on their Fock state distribution, asymmetric field quadrature variances, and do not minimize the uncertainty relation for the field quadratures. These properties are analytically controlled by the para-Bose order and the evolution time; both parameters might be feasible for fine tuning in the trapped-ion quantum simulation.

Vínculos sobre um modelo de quartessência de Chaplygin usando observações do satélite chandra da fração de massa de gás em aglomerados de galáxias

NASA Astrophysics Data System (ADS)

de Souza, R. S.

2003-08-01

Observações de Supernovas do tipo Ia mostram que a expansão do Universo está acelerando. Segundo as equações de Einstein uma componente com pressão negativa (energia escura) é necessária para explicar a aceleração cósmica. Além da energia escura é usualmente admitido que no Universo há também uma matéria exótica com pressão zero, que é chamada de matéria escura. Essa componente possui um papel fundamental na formação de estruturas no Universo. Recentemente tem se explorado a possibilidade de que matéria e energia escura poderiam ser unificadas através de uma única componente, que tem sido denominada de quartessência. Um exemplo de fluido com essas características é o Gás de Chaplygin Generalizado, que possui uma equação de estado da forma p = -A/ra. Inicialmente consideramos o caso especial a = 1 (gás de Chaplygin) e vinculamos parâmetros do modelo utilizando observações em raios-X do satélite Chandra da fração de massa de gás em aglomerados de galáxias. Uma comparação dos vínculos obtidos com esse teste com outros testes, tais como supernovas e idade do Universo, mostra que esse teste é bastante restritivo. Exibiremos ainda resultados para o caso em que a curvatura é nula e o parâmetro a está compreendido no intervalo -1 < a 1.

Revision curricular a partir de un analisis comparativo de las discrepancias en los curriculos de una escuela de optometria en Puerto Rico con las competencias requeridas para las agencias de revalida y acreditacion 2004

NASA Astrophysics Data System (ADS)

Rivera Pacheco, Andres

El proposito de esta investigacion, un estudio cualitativo de caso, fue comparar y contrastar el curriculo vigente de la Escuela de Optometria de la UIAPR con las competencias y estandares requeridos por las agencias de acreditacion y de revalida. Con este proposito, decidimos realizar una revision y un analisis de documentos: el prontuario de cada uno de los cursos de los curriculos implantados en el 1993 y en el 2001; las competencias y estandares establecidos por las agencias de revalida y de acreditacion; y las estadisticas en las que se analiza el porcentaje de estudiantes que aprueban cada una de las partes de los examenes de revalida entre el 1998 al 2003. Se realizaron entrevistas dirigidas para dar apoyo y complementar la revision y el analisis de estos documentos. Los participantes de las entrevistas fueron tres estudiantes de la clase de optometria del 2004 (ultima clase del curriculo del 1993); tres estudiantes de la clase de optometria del 2005 (primera clase graduanda del curriculo vigente) y tres profesores y/o directores de los Departamentos de Ciencias Basicas, Ciencias Clinicas y Cuidado al Paciente. Esta investigacion se enmarco en el modelo de evaluacion curricular de discrepancia de Malcolm Provus y en el modelo de desarrollo basado en competencias. Uno de los hallazgos mas importantes del estudio es que los cambios que se implantaron al curriculo del 2001 no han logrado que los estudiantes mejoren su ejecucion en los examenes de revalida. Por otro lado, se encontro que el curriculo vigente atiende completamente los estandares de la practica de Optometria, pero no las competencias. Esta informacion fue validada mediante el uso de una tabla de cotejo para el analisis de los cursos y de la informacion obtenida de las entrevistas. El estudio determina y concluye que existen discrepancias entre los prontuarios de los cursos del curriculo y las competencias requeridas por la agencia de revalida. Segundo, que el Departamento de Ciencias Basicas es el

Geographic Variation Immediate and Delayed Breast Reconstruction Utilization in Ontario, Canada and Plastic Surgeon Availability: A Population-Based Observational Study.

PubMed

Platt, Jennica; Zhong, Toni; Moineddin, Rahim; Booth, Gillian L; Easson, Alexandra M; Fernandes, Kimberly; Gozdyra, Peter; Baxter, Nancy N

2015-08-01

Utilization of breast reconstruction (BR) is low in many jurisdictions. We studied the geographical and surgical workforce factors that contribute to access and use of BR using a small area analysis approach with a geographical unit of analysis. We linked administrative data from Ontario Canada to calculate the age-standardized rates for immediate BR (IBR) (same time as mastectomy) between 2002 and 2011, and delayed BR (DBR) (within 3 years of mastectomy) for each county. The influence of plastic surgeon access on variation in county rates of BR was examined using Poisson random effects models. 12,663 women underwent mastectomy in Ontario; 2,948 had BR within 3 years (23.3%). Over 50% of the counties had no access to any plastic surgeon. County IBR rates ranged from 0 to 21.5%; plastic surgeon access explained 46% of geographic variation (p<0.0001). IBR rates in counties with very low, low, and moderate access to plastic surgeons were significantly less than counties with high access (relative rate [RR] 0.48 [95% confidence interval (CI) 0.35-0.66], RR 0.61 [CI 0.43-0.87] and RR 0.70 [CI 0.52-0.96], respectively) after adjusting for age and county socioeconomic characteristics. For DBR, while there was less geographic variation, very low access counties demonstrated reduced rates (RR 0.60 [CI 0.47-0.76]). Geographic access to a plastic surgeon is a major determinant of BR. Targeted interventions for regions without high access to plastic surgeons may improve overall rates and reduce geographic disparities in care, particularly for IBR.

Determinación de temperatura efectiva y gravedad superficial de estrellas B y A de secuencia principal

NASA Astrophysics Data System (ADS)

Nieva, M. F.; Pintado, O. I.; Adelman, S.; Rayle, K. E.; Sanders, S. E., Jr.

Las temperaturas efectivas (Teff) y gravedades superficiales (log g) de un grupo de estrellas de tipo B y A de Secuencia Principal se determinaron en varias etapas. En una primera aproximación se usaron los índices fotométricos de Strömgren para realizar el cálculo con el programa de Napiwotski et al.(1993). Luego se hizo un ajuste comparando datos espectrofotométricos con flujos obtenidos con el modelo ATLAS9 en la región visible. Y a continuación se hizo un mejor ajuste comparando los perfiles de la línea Hγ con espectros sintéticos calculados con SYNTHE. Además, se analizó el efecto de usar el modelo de Canuto y Mazzitelli (1991), donde se considera The Mixing Length Theory, en modelos de atmósferas de estrellas.

Theoretical studies of solar-pumped lasers

NASA Technical Reports Server (NTRS)

Harries, W. L.

1982-01-01

Solar-pumped lasers were investigated by comparing experimental results from pulse experiments with steady state calculations. The time varying behavior of an IBr laser is studied. The analysis is only approximate, but indicates that conditions occurring in a pulsed experiment are quite different from those at steady state. The possibility of steady-state lasing in an IBr laser is determined. The effects of high temperatures on the quenching and recombination rates are examined. Although uncertainties in the values of the rate coefficients make it difficult to draw firm conclusions, it seems steady state running may be possible at high temperatures.

Morfología de la Coma del Cometa Hale - Bopp

NASA Astrophysics Data System (ADS)

Gil-Hutton, R.; Caballero, M.; Coldwell, G.; Cañada, M.; Godoy, G.; Trozzo, C.; Gómez, G.

Para lograr comprender plenamente los procesos físicos que se desarrollan en los núcleos cometarios y obtener un modelo que explique, no sólo su actividad, sino también sus efectos sobre la coma, es necesario obtener información detallada para el mayor número de cometas posible, siendo las características más interesantes para estudiar la ubicación de las regiones activas, la presencia de jets, las tasas de producción de gas y polvo y la interacción de la coma con el viento solar. En la actualidad, con técnicas de procesamiento de imágenes y tecnología CCD se pueden obtener este tipo de datos para cometas que ingresan al sistema solar interior y estudiar, de esta manera, la morfología de sus comas, tratando de correlacionar la actividad detectada con algún modelo teórico. En este trabajo se presenta un estudio parcial de la actividad desarrollada por el cometa Hale-Bopp, y sus efectos sobre la morfología de su coma, desde agosto de 1995 hasta la fecha en base a imágenes adquiridas con el telescopio de 0.76 m. de la Estación Astronómica Dr. Carlos Ulrrico Cesco.

The para-HK/QK correspondence

NASA Astrophysics Data System (ADS)

Dyckmanns, Malte; Vaughan, Owen

2017-06-01

We generalise the hyper-Kähler/quaternionic Kähler (HK/QK) correspondence to include para-geometries, and present a new concise proof that the target manifold of the HK/QK correspondence is quaternionic Kähler. As an application, we construct one-parameter deformations of the temporal and Euclidean supergravity c-map metrics and show that they are para-quaternionic Kähler.

MODELO PARA EVALUACION DE DERRAMES DE HIDROCARBUROS (HSSM) GUIA DEL USUARIO

EPA Science Inventory

The U.S. Environmental Protection Agency is charged by Congress with protecting the Nation's land, air, and water resources. Under a mandate of national environmental laws, the Agency strives to formulate and implement actions leading to a compatible balance between human acti...

A suture delta: the co-evolution of tectonics and sedimentology as a remnant ocean basin closes; the Indo Burman ranges, northeast India and Bangladesh

NASA Astrophysics Data System (ADS)

Sincavage, R.; Betka, P. M.; Seeber, L.; Steckler, M. S.; Zoramthara, C.

2017-12-01

The closure of an ocean basin involves the interplay of tectonics and sedimentology, whereby thick successions of fluvio-deltaic and shallow marine sediment accumulate in the closing gap between the subduction zone and passive margin. The transition from subduction to collision involves processes that are inherently time-transgressive and co-evolve to influence the nature of the developing tectonic wedge. The Indo-Burman Ranges (IBR) of eastern India present a unique opportunity to examine this scenario on a variety of spatial (10-2­­­-105 m2) and temporal (1 a-10 Ma) scales. Recent field mapping campaigns in the IBR have illuminated analogous depositional environments expressed in the Neogene outcrops of the IBR and the Holocene sediment archive of the Ganges-Brahmaputra-Meghna delta (GBMD). Six distinct lithofacies are present in shallow-marine to fluvial strata of the IBR, containing sedimentary structures that reflect depositional environments correlative with the modern delta. Cyclical alternations of fine sands and silts in packages on the order of 15-20 cm thick define part of the shallow-marine section (M2 facies) that we interpret to represent the foreset beds of the ancient subaqueous delta. The overall scale and sedimentary structures of M2 compare favorably with modern foreset deposits in the Bay of Bengal. Tan-orange medium-grained, well sorted fluvial sandstone that contain large scale (1-10 m) tabular and trough cross bedding represent large-river channel deposits (F2 facies) that overlie the shallow marine strata. F2 deposits bear a striking resemblance in scale and character to bar deposits along the modern Jamuna River. Preliminary grain size analyses on the F2 facies yield grain size distributions that are remarkably consistent with Brahmaputra-sourced mid-Holocene sediments from Sylhet basin within the GBMD. Current research on the GBMD has revealed quantifiable trends in bed thicknesses, downstream fining, and grain size within fluvial

Applying DNA Barcodes to Identify Closely Related Species of Ferns: A Case Study of the Chinese Adiantum (Pteridaceae)

PubMed Central

Wen, Jun; Ebihara, Atsushi; Li, De-Zhu

2016-01-01

DNA barcoding is a fast-developing technique to identify species by using short and standard DNA sequences. Universal selection of DNA barcodes in ferns remains unresolved. In this study, five plastid regions (rbcL, matK, trnH-psbA, trnL-F and rps4-trnS) and eight nuclear regions (ITS, pgiC, gapC, LEAFY, ITS2, IBR3_2, DET1, and SQD1_1) were screened and evaluated in the fern genus Adiantum from China and neighboring areas. Due to low primer universality (matK) and/or the existence of multiple copies (ITS), the commonly used barcodes matK and ITS were not appropriate for Adiantum. The PCR amplification rate was extremely low in all nuclear genes except for IBR3_2. rbcL had the highest PCR amplification rate (94.33%) and sequencing success rate (90.78%), while trnH-psbA had the highest species identification rate (75%). With the consideration of discriminatory power, cost-efficiency and effort, the two-barcode combination of rbcL+ trnH-psbA seems to be the best choice for barcoding Adiantum, and perhaps basal polypod ferns in general. The nuclear IBR3_2 showed 100% PCR amplification success rate in Adiantum, however, it seemed that only diploid species could acquire clean sequences without cloning. With cloning, IBR3_2 can successfully distinguish cryptic species and hybrid species from their related species. Because hybridization and allopolyploidy are common in ferns, we argue for including a selected group of nuclear loci as barcodes, especially via the next-generation sequencing, as it is much more efficient to obtain single-copy nuclear loci without the cloning procedure. PMID:27603700

Model determination in a case of heterogeneity of variance using sampling techniques.

PubMed

Varona, L; Moreno, C; Garcia-Cortes, L A; Altarriba, J

1997-01-12

A sampling determination procedure has been described in a case of heterogeneity of variance. The procedure makes use of the predictive distributions of each data given the rest of the data and the structure of the assumed model. The computation of these predictive distributions is carried out using a Gibbs Sampling procedure. The final criterion to compare between models is the Mean Square Error between the expectation of predictive distributions and real data. The procedure has been applied to a data set of weight at 210 days in the Spanish Pirenaica beef cattle breed. Three proposed models have been compared: (a) Single Trait Animal Model; (b) Heterogeneous Variance Animal Model; and (c) Multiple Trait Animal Model. After applying the procedure, the most adjusted model was the Heterogeneous Variance Animal Model. This result is probably due to a compromise between the complexity of the model and the amount of available information. The estimated heritabilities under the preferred model have been 0.489 ± 0.076 for males and 0.331 ± 0.082 for females. RESUMEN: Contraste de modelos en un caso de heterogeneidad de varianzas usando métodos de muestreo Se ha descrito un método de contraste de modelos mediante técnicas de muestreo en un caso de heterogeneidad de varianza entre sexos. El procedimiento utiliza las distribucviones predictivas de cada dato, dado el resto de datos y la estructura del modelo. El criterio para coparar modelos es el error cuadrático medio entre la esperanza de las distribuciones predictivas y los datos reales. El procedimiento se ha aplicado en datos de peso a los 210 días en la raza bovina Pirenaica. Se han propuesto tres posibles modelos: (a) Modelo Animal Unicaracter; (b) Modelo Animal con Varianzas Heterogéneas; (c) Modelo Animal Multicaracter. El modelo mejor ajustado fue el Modelo Animal con Varianzas Heterogéneas. Este resultado es probablemente debido a un compromiso entre la complejidad del modelo y la cantidad de datos

Separating para and ortho water.

PubMed

Horke, Daniel A; Chang, Yuan-Pin; Długołęcki, Karol; Küpper, Jochen

2014-10-27

Water exists as two nuclear-spin isomers, para and ortho, determined by the overall spin of its two hydrogen nuclei. For isolated water molecules, the conversion between these isomers is forbidden and they act as different molecular species. Yet, these species are not readily separated, and no pure para sample has been produced. Accordingly, little is known about their specific physical and chemical properties, conversion mechanisms, or interactions. The production of isolated samples of both spin isomers is demonstrated in pure beams of para and ortho water in their respective absolute ground state. These single-quantum-state samples are ideal targets for unraveling spin-conversion mechanisms, for precision spectroscopy and fundamental symmetry-breaking studies, and for spin-enhanced applications, for example laboratory astrophysics and astrochemistry or hypersensitized NMR experiments. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Identificabilidade e estabilidade dos parâmetros no método Grade of Membership (GoM): considerações metodológicas e práticas

PubMed Central

Guedes, Gilvan Ramalho; Caetano, André Junqueira; Machado, Carla Jorge; Brondízio, Eduardo Sonewend

2011-01-01

O método Grade of Membership (GoM) tem sido cada vez mais utilizado por demógrafos brasileiros e tem a vantagem de possuir um parâmetro que mensura a heterogeneidade individual, com base nas correlações não-observáveis entre as categorias de resposta das variáveis de interesse, gerando um medida do grau de pertencimento de cada indivíduo a perfis extremos. Alguns autores, contudo, chamam atenção para questões importantes na calibragem dos modelos finais que utilizam o programa GoM versão 3.4, como o problema de identificabilidade – soluções múltiplas para parâmetros estimados. Neste artigo, é sugerido um procedimento capaz de identificar um modelo final com solução única que descreva os tipos puros mais fidedignos à base de dados, em uma tentativa de otimização. Para ilustrar esse processo, utilizou-se uma base de dados correspondente a um levantamento econômico e sociodemográfico de uma população de pequenos agricultores residentes ao longo da Rodovia Transamazônica, no Estado do Pará. Também identificou-se a existência de instabilidade nos parâmetros estimados pelo programa GoM 3.4, sendo proposto um método de estabilização de seus valores. Com esses procedimentos combinados, os usuários do programa GoM 3.4 poderão descrever sua base de dados de forma mais adequada e responder às críticas sobre questões de identificabilidade e estabilidade dos modelos resultantes. Essas soluções empíricas são relevantes por afetarem cálculos de prevalência e de incidência de eventos de interesse, além de trazerem consequências importantes sobre o ponto e o momento corretos para intervenções de políticas públicas ou de planejamento prospectivo em análises de projeção. PMID:21709732

Cinética Química: el laboratorio

NASA Astrophysics Data System (ADS)

Cabañas Galán, B.

La interpretación de las transformaciones químicas que se producen en la atmósfera requiere un profundo conocimiento de la cinética, productos y mecanismos de reacción de las posibles interacciones que pueden ocurrir entre las distintas especies presentes en ella. Información cuantitativa de este tipo es un prerrequisito para la construcción de modelos numéricos adecuados que expliquen el comportamiento químico-físico de la atmósfera. Esta información se obtiene a partir de experimentos realizados en laboratorios y por tanto independiente de medidas atmosféricas, por lo que los modelos atmosféricos derivados de ellos, pueden usarse para diagnosticar y predecir adecuadamente el comportamiento atmosférico. En esta exposición se recogen las técnicas experimentales más extendidas para la obtención de datos cinéticos así como los métodos de análisis de datos más utilizados en el estudio de las distintas reacciones de interés atmosférico. Se analizan sus características generales así como su adecuación a los distintos tipos de reacciones.

The Practice of Research of a Basic Education Teacher Involving Mental Models of the Phases of the Moon and Eclipses. (Spanish Title: La Práctica de Investigación de un Maestro de Educación BÁsica con El Uso de los Modelos Mentales de Las Fases de la Luna Y Eclipses.) A Prática de Pesquisa de um Professor do Ensino Fundamental Envolvendo Modelos Mentais de Fases da Lua e Eclipses

NASA Astrophysics Data System (ADS)

Pessôa Queiroz, Glória; Jubitipan Borges de Sousa, Carlos; Auxiliadora Delgado Machado, Maria

2009-12-01

docente. La formación de grupos interinstitucionales para la planificación de la acción y la investigación ha resultado productiva para el trabajo de construcción de conocimiento de apoyo a los procesos educativos en la escuela, mientras que la universidad enriquece su colección de experiencias validadas, considerando los resultados de la educación inicial y continua de maestros. La participación activa del maestro en un grupo de investigación en la universidad lo llevó a reflexiones sobre los posibles caminos didácticos que pueden ser descriptos, analizados y comunicados a los demás docentes. La construcción de una pedagogía propia, que tuvo en cuenta los modelos mentales de los estudiantes sobre los temas básicos de astronomía, y los cambios desarrollados a partir de las lecciones que enseñó, trajeron consecuencias de largo alcance sobre la pedagogía adoptada por el maestro, que ahora incorpora una nueva visión de la ciencia y formas alternativas al diálogo con los estudiantes, los componentes esenciales para un investigador en Educaciónen Ciencias. A inclusão do professor da escola básica no universo da pesquisa é questão controvertida e em pleno debate no meio acadêmico. A oportunidade de trabalho coletivo que incorporou professores de uma escola municipal no Rio de Janeiro a um grupo de ensino de Física da universidade nos possibilitou vislumbrar a ressignificação da função de um professor de Ciências (co-autor deste trabalho) por ele próprio, agora passando a incluir a pesquisa sobre a construção de conhecimento pelos alunos em sua prática como docente. A formação de grupos interinstitucionais para o planejamento de ações e de pesquisas tem-se mostrado produtiva para um trabalho de construção de conhecimentos a fim de subsidiar processos educativos na escola, ao mesmo tempo em que a universidade enriquece seu acervo de experiências validadas criticamente, podendo considerar seus resultados na formação inicial e

Fotoexcitación de Moléculas Pequeñas

NASA Astrophysics Data System (ADS)

González Díaz, P. F.

El modelo estocástico no puede justificar la excitación multi-fotónica de moléculas pequeñas o muy simétricas. Basándonos en un escenario de interacción radiación-molécula cooperativo para la absorción de N-1 fotones IR por un sistema de N niveles, se especula que un posible mecanismo para la excitación no estocástica de moléculas pudiera ser la generación de procesos caóticos intra-moleculares.

Las líneas de aluminio neutro como diagnóstico cromosférico

NASA Astrophysics Data System (ADS)

Fernández Borda, R.; Mauas, P. J. D.

Se presenta un modelo atómico para el cálculo de las lí neas del Aluminio neutro que se forman en la cromósfera solar. En particular, se estudia la línea λ 3961 Å, que, por estar muy próxima a la lí nea H del Ca II y a Hɛ es muy frecuentemente observada. Observaciones en esta lí nea obtenidas con el espectrógrafo a instalarse en el CASLEO, serán utilizadas para el estudio de fulguraciones solares.

Neoadjuvant radiotherapy followed by mastectomy and immediate breast reconstruction : An alternative treatment option for locally advanced breast cancer.

PubMed

Pazos, Montserrat; Corradini, Stefanie; Dian, Darius; von Bodungen, Vera; Ditsch, Nina; Wuerstlein, Rachel; Schönecker, Stephan; Harbeck, Nadia; Scheithauer, Heike; Belka, Claus

2017-04-01

The optimal sequence of mastectomy with immediate breast reconstruction (IBR) and radiotherapy (RT) for the treatment of locally advanced breast cancer (LABC) is still under debate. Increased rates of postoperative complications are described following postmastectomy RT. Neoadjuvant RT aims to improve the aesthetic results and simplify the reconstructive pathway. A total of 22 patients diagnosed with LABC and treated with neoadjuvant RT followed by mastectomy and IBR between 04/2012 and 03/2015 were retrospectively analyzed. RT consisted of external beam RT to the breast and the regional lymphatics, if indicated. Both implant-based and autologous tissue-transfer reconstruction techniques were used. At the time of RT, 10 patients had no prior surgery and 12 patients had previously undergone breast-conserving surgery (BCS) with positive resection margins without the possibility to perform a second BCS. Additional neoadjuvant chemotherapy was administered in 18 patients prior to RT. A complete pathological response was achieved in 55.0% of patients. The 2‑year overall survival rate was 89.3%, the 2‑year disease-free-survival 79.8% and the local-recurrence-free survival was 95.2%. The cosmetic result was excellent or good in 66% of the patients treated with upfront mastectomy and 37% of the patients who had previously undergone BCS. Among patients who received implant-based IBR, 4 patients developed serious wound-healing problems with implant loss. The most satisfactory results were achieved with autologous tissue reconstruction. A sequential neoadjuvant chemo-/radiotherapy to allow IBR following mastectomy in selected cases of LABC seems feasible and can be safely attempted. Careful patient selection, close monitoring, and continuous patient support is mandatory to ensure compliance in this treatment strategy.

Improved immediate breast reconstruction as a result of oncoplastic multidisciplinary meeting.

PubMed

El Gammal, Mohsen M; Lim, Maria; Uppal, Rajan; Sainsbury, Richard

2017-01-01

The National Institute for Health and Clinical Excellence guidelines recommend that breast reconstruction should be available to all women undergoing mastectomy and discussed at the initial surgical consultation (2002, and updated 2009). The National Mastectomy and Breast Reconstruction Audit (2009) showed that 21% of mastectomy patients underwent immediate breast reconstruction (IBR) and 11% had delayed breast reconstruction (DBR). Breast reconstruction has been shown to have a positive effect on quality of life postmastectomy. This retrospective study investigated the impact of the introduction of a dedicated oncoplastic multidisciplinary meeting (OP MDM) on our unit's breast reconstruction rate. A retrospective analysis of 229 women who underwent mastectomy, of whom 81 (35%) underwent breast reconstruction between April 2014 and March 2016. Data were analyzed before and after introduction of OP MDM in April 2015. Data on patient age, type of surgery (mastectomy only, mastectomy and reconstruction), timing of reconstruction (IBR, DBR), and type of reconstruction (implant, autologous) were collected. Between April 2015 and March 2016, following establishment of OP multidisciplinary team in April 2015, of the 120 patients who had mastectomy, 50 (42%) underwent breast reconstruction with 78% (39/50) choosing IBR (56% implant reconstruction and 22% autologous). Compared to the period between April 2014 and March 2015 preceding the OP MDM, of 109 patients who underwent mastectomy, only 31 (28%) had breast reconstruction with 64% (20/31) choosing IBR (45% implant reconstruction and 19% autologous). The rate of DBR was lower, 22% (11/50), following OP MDM compared to 35% (11/31) before OP MDM. There has been an increased uptake of breast reconstruction surgery from 28% to 42%. The biggest impact was on those opting for the immediate type reconstruction option (78%). The OP MDM has significantly contributed to this increased rate of reconstruction.

A denuder-impinger system with in situ derivatization followed by gas chromatography-mass spectrometry for the determination of gaseous iodine-containing halogen species.

PubMed

Huang, Ru-Jin; Hoffmann, Thorsten

2008-11-14

Reactive iodine species have been suggested to play an important role in the atmosphere (e.g. tropospheric ozone depletion, coastal new particle formation). However, there still exist major uncertainties about their atmospheric chemistry, mostly due to the lack of analytical approaches for the accurate speciation of certain key compounds. In this study, 1,3,5-trimethoxybenzene (1,3,5-TMB)-coated denuder proved to be suitable for the differentiation between gaseous interhalogens (iodine monochloride (ICl), iodine monobromide (IBr)) and molecular iodine (I2) based on a selective collection/derivatization method. The results of the denuder sampling were compared with the results of impinger sampling in water, methanol and carbon tetrachloride solutions of 1,3,5-TMB. ICl and IBr are converted into 1-iodo-2,4,6-trimethoxybenzene (1-iodo-2,4,6-TMB) and 1-bromo-2,4,6-trimethoxybenzene (1-bromo-2,4,6-TMB), respectively, in the denuder systems. The respective collection efficiency is 99.2% for ICl and 92.6% for IBr, at 500mLmin(-1) gas flow rate. The collection efficiency for I2 is lower than 1% in the same denuder system, but significantly increases to about 90% in the aqueous 1,3,5-TMB loaded impinger. The denuder-impinger coupled system was then used to differentiate and to collect the ICl, IBr and I2 gas mixtures, followed by gas chromatography-ion trap mass spectrometry (GC-MS) determination. The precision of the method is in general better than 9.1%. The parameters affecting denuder operation including sampling flow rate, sampling duration, and relative humidity have been evaluated. The presented method provides an attractive protocol for iodine species analysis for atmospheric chemistry research.

CYP96T1 of Narcissus sp. aff. pseudonarcissus Catalyzes Formation of the Para-Para' C-C Phenol Couple in the Amaryllidaceae Alkaloids

PubMed Central

Kilgore, Matthew B.; Augustin, Megan M.; May, Gregory D.; Crow, John A.; Kutchan, Toni M.

2016-01-01

The Amaryllidaceae alkaloids are a family of amino acid derived alkaloids with many biological activities; examples include haemanthamine, haemanthidine, galanthamine, lycorine, and maritidine. Central to the biosynthesis of the majority of these alkaloids is a C-C phenol-coupling reaction that can have para-para', para-ortho', or ortho-para' regiospecificity. Through comparative transcriptomics of Narcissus sp. aff. pseudonarcissus, Galanthus sp., and Galanthus elwesii we have identified a para-para' C-C phenol coupling cytochrome P450, CYP96T1, capable of forming the products (10bR,4aS)-noroxomaritidine and (10bS,4aR)-noroxomaritidine from 4′-O-methylnorbelladine. CYP96T1 was also shown to catalyzed formation of the para-ortho' phenol coupled product, N-demethylnarwedine, as less than 1% of the total product. CYP96T1 co-expresses with the previously characterized norbelladine 4′-O-methyltransferase. The discovery of CYP96T1 is of special interest because it catalyzes the first major branch in Amaryllidaceae alkaloid biosynthesis. CYP96T1 is also the first phenol-coupling enzyme characterized from a monocot. PMID:26941773

Dinámica de planetas extrasolares resonantes

NASA Astrophysics Data System (ADS)

Beauge, C.

Actualmente se han detectado 117 planetas alrededor de estrellas de Secuencia Principal, incluyendo 12 sistemas planetarios, cada uno con dos o tres miembros. De estos últimos, ocho poseen planetas en órbitas próximas y sus perturbaciones gravitacionales se convierten en un factor fundamental para la estabilidad orbital del sistema. Todos se encuentran en configuraciones resonantes, desde la conmensurabilidad de movimientos 2/1 de Gliese 876, hasta la resonancia secular de Ups And. En esta presentación analizamos varios aspectos de la dinámica resonante de los planetas extrasolares, incluyendo la existencia de soluciones de equilibrio, construcción de modelos analógicos y métodos para la determinación de masas individuales. También discutimos por qué las resonancias son tan frecuentes en estos sistemas, comparado con nuestro propio Sistema Solar. Por último, intentamos relacionar estos modelos con la hipótesis de migración planetaria, buscando límites en su extensión y en los posibles mecanismos que le dieron origen.

Perda de massa em ventos empoeirados de estrelas supergigantes

NASA Astrophysics Data System (ADS)

Vidotto, A. A.; Jatenco-Pereira, V.

2003-08-01

Em praticamente todas as regiões do diagrama HR, as estrelas apresentam evidências observacionais de perda de massa. Na literatura, pode-se encontrar trabalhos que tratam tanto do diagnóstico da perda de massa como da construção de modelos que visam explicá-la. O amortecimento de ondas Alfvén tem sido utilizado como mecanismo de aceleração de ventos homogêneos. Entretanto, sabe-se que os envelopes de estrelas frias contêm grãos sólidos e moléculas. Com o intuito de estudar a interação entre as ondas Alfvén e a poeira e a sua conseqüência na aceleração do vento estelar, Falceta-Gonçalves & Jatenco-Pereira (2002) desenvolveram um modelo de perda de massa para estrelas supergigantes. Neste trabalho, apresentamos um estudo do modelo acima proposto para avaliar a dependência da taxa de perda de massa com alguns parâmetros iniciais como, por exemplo, a densidade r0, o campo magnético B0, o comprimento de amortecimento da onda L0, seu fluxo f0, entre outros. Sendo assim, aumentando f0 de 10% a partir de valores de referência, vimos que aumenta consideravelmente, enquanto que um aumento de mesmo valor em r0, B0 e L0 acarreta uma diminuição em .

Cooling by Para-to-Ortho-Hydrogen Conversion

NASA Technical Reports Server (NTRS)

Sherman, A.; Nast, T.

1983-01-01

Catalyst speeds conversion, increasing capacity of solid hydrogen cooling system. In radial-flow catalytic converter, para-hydrogen is converted to equilibrium mixture of para-hydrogen and ortho-hydrogen as it passes through porous cylinder of catalyst. Addition of catalyst increases capacity of hydrogen sublimation cooling systems for radiation detectors.

An integrated biomarker response index for the mussel Mytilus edulis based on laboratory exposure to anthracene and field transplantation experiments

NASA Astrophysics Data System (ADS)

Yuan, Mengqi; Wang, You; Zhou, Bin; Jian, Xiaoyang; Dong, Wenlong; Tang, Xuexi

2017-09-01

Organic pollution is a serious environmental problem in coastal areas and it is important to establish quantitative methods for monitoring this pollution. This study screened a series of sensitive biomarkers to construct an integrated biomarker response (IBR) index using Mytilus edulis. Mussels were exposed to the polycyclic aromatic hydrocarbon anthracene under controlled laboratory conditions and the activities of components of the glutathione antioxidant system, and the concentrations of oxidative-damage markers, were measured in the gills and digestive glands. Anthracene exposure resulted in increased levels of malondialdehyde (MDA) and superoxide radicals (O 2 • ), indicating that oxidative damage had occurred. Correspondingly, anthracene exposure induced increased activities of glutathione S-transferase (GST), glutathione peroxidase (GPx) and reduced glutathione (GSH) in digestive glands, and GPx and glutathione reductase (GR) in gills, consistent with stimulation of the antioxidant system. A field experiment was set up, in which mussels from a relatively clean area were transplanted to a contaminated site. One month later, the activities of GST, GPx and GR had increased in several tissues, particularly in the digestive glands. Based on the laboratory experiment, an IBR, which showed a positive relationship with anthracene exposure, was constructed. The IBR is suggested to be a potentially useful tool for assessing anthracene pollution.

ParaChoice Model.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heimer, Brandon Walter; Levinson, Rebecca Sobel; West, Todd H.

Analysis with the ParaChoice model addresses three barriers from the VTO Multi-Year Program Plan: availability of alternative fuels and electric charging station infrastructure, availability of AFVs and electric drive vehicles, and consumer reluctance to purchase new technologies. In this fiscal year, we first examined the relationship between the availability of alternative fuels and station infrastructure. Specifically, we studied how electric vehicle charging infrastructure affects the ability of EVs to compete with vehicles that rely on mature, conventional petroleum-based fuels. Second, we studied how the availability of less costly AFVs promotes their representation in the LDV fleet. Third, we used ParaChoicemore » trade space analyses to help inform which consumers are reluctant to purchase new technologies. Last, we began analysis of impacts of alternative energy technologies on Class 8 trucks to isolate those that may most efficaciously advance HDV efficiency and petroleum use reduction goals.« less

Clinical outcome and patient satisfaction with the use of bovine-derived acellular dermal matrix (SurgiMend™) in implant based immediate reconstruction following skin sparing mastectomy: A prospective observational study in a single centre.

PubMed

Headon, Hannah; Kasem, Abdul; Manson, Aisling; Choy, Christina; Carmichael, Amtul R; Mokbel, Kefah

2016-06-01

The advent of acellular dermal matrix devices (ADMs) has enhanced both the scope of implant-based immediate breast reconstruction (IBR) following skin sparing mastectomy (SSM) for the treatment or risk reduction of breast cancer. Currently, there are a wide range of options available for the use of ADMs. This is a prospective observational single institution study of 118 consecutive patients undergoing a total of 164 SSM and IBR procedures either for treatment for breast cancer or for risk reduction, between 2012 and 2014. IBR was performed using an implant and bovine-derived ADM (SurgiMend™). Nipple sparing mastectomy (NSM) accounted for 103 procedures. IBR was performed as a single stage procedure in 23% of patients. The primary endpoint of this prospective study was the explantation rate and secondary endpoints included quality of life, patient satisfaction, aesthetic outcome assessed objectively, surgical complications, overall and disease free survival. Forty-six patients (39%) had a bilateral and 72 underwent a unilateral SSM. Of those who underwent a unilateral SSM, 25 had a contralateral adjustment procedure. Out of 164 procedures, 117 (71%) were for the treatment of breast cancer. Sixty-one patients received chemotherapy (52%) and 32 (27%) had radiotherapy. In this study 27 patients underwent post-mastectomy radiotherapy. At a mean follow of 21 months, the explantation rate was 1.2%, 4% (6 patients) developed wound complications. The patient satisfaction with the procedure was found to be very high. The mean Breast Q Score was 85 and the mean overall patient satisfaction rating was 9 out of a possible 10. The mean objective assessment score was 8.9 out of a possible 10 and the mean subjective capsular contracture severity score was 2.9 out of 10. There were two cases of local recurrence (1.7%), one distant recurrence (0.8%) and one patient died of metastatic breast cancer (0.8%). Overall survival was 99.2% and locoregional disease free survival (LRFS

21 CFR 184.1443 - Magnesium sulfate.

Code of Federal Regulations, 2012 CFR

2012-04-01

... is incorporated by reference. Copies are available from the National Academy Press, 2101 Constitution...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In...

Study on cross-reactivity to the para group.

PubMed

Picardo, M; Cannistraci, C; Cristaudo, A; De Luca, C; Santucci, B

1990-01-01

In 80 patients, positive to at least one hapten of the para group (para-phenylenediamine, diaminodiphenylmethane, benzocaine, PPD mix), patch tests were carried out with freshly prepared solutions of para-phenylenediamine (PPD) and of 3 selected aromatic compounds related structurally to PPD (para-aminophenol, ortho-aminophenol, hydroquinone). The number of positive reactions correlated with the rate of decomposition of the substances as evaluated by high-pressure liquid chromatography. PPD, which was almost decomposed after 24 h, gave the highest number of positive reactions, followed by ortho-aminophenol and by para-aminophenol, while hydroquinone, which was oxidized to the extent of 35%, did not give any reactions. To evaluate if a different rate of oxidation can modify the patch test response, in the same patients and in 10 normal volunteers, tests were carried out with PPD solutions containing the oxidizing agent silver oxide (0.1%). By this procedure a significant increase in the number of positive responses was observed. The results suggest that the rate of decomposition and therefore the amount of quinone(s) generated, might be the key to eliciting patch test responses to oxidizable aromatic haptens.

Programa de conservacion para aves migratorias neotropicales

Treesearch

Deborah Finch; Marcia Wilson; Roberto Roca

1992-01-01

Mas de 250 especies de aves terrestres migran a Norte America durante la epoca reproductiva para aprovechar los sistemas templados. No obstante, las aves migratorias neotropicales pasan la mayor parte de su ciclo de vida en los habitat tropicales y subtropicales de paises latinoamericanos y caribefios donde viven en una asociacion cercana con las aves residentes. Para...

Polymorphism and Modulation of Para-Substituted l-Phenylalanine.

PubMed

Sögütoglu, Leyla-Cann; Lutz, Martin; Meekes, Hugo; de Gelder, René; Vlieg, Elias

2017-12-06

The crystal structure of para -methyl-l-phenylalanine at 230 K resembles that of the para-fluorinated analogue from the literature but is commensurately modulated with seven molecules in the asymmetric unit ( Z ' = 7). At 100 K, the superstructure loses its modulation, leading to a unit cell with Z ' = 1, with clear disorder in the phenyl ring orientations. The methyl-substituent in para -methyl-l-phenylalanine has, in contrast to fluorine, no polar interactions with protons of neighboring molecules, which might allow for the well-defined modulation of the crystal structure at 230 K.

Para hydrogen equilibration in the atmospheres of the outer planets

NASA Technical Reports Server (NTRS)

Conrath, Barney J.

1986-01-01

The thermodynamic behavior of the atmospheres of the Jovian planets is strongly dependent on the extent to which local thermal equilibration of the ortho and para states of molecular hydrogen is achieved. Voyager IRIS data from Jupiter imply substantial departures of the para hydrogen fraction from equilibrium in the upper troposphere at low latitudes, but with values approaching equilibrium at higher latitudes. Data from Saturn are less sensitive to the orth-para ratio, but suggest para hydrogen fractions near the equilibrium value. Above approximately the 200 K temperature level, para hydrogen conversion can enhance the efficiency of convection, resulting in a substantial increase in overturning times on all of the outer planets. Currently available data cannot definitively establish the ortho-para ratios in the atmospheres of Uranus and Neptune, but suggest values closer to local equilibrium than to the 3.1 normal ratio. Modeling of sub-millimeter wavelength measurements of these planets suggest thermal structures with frozen equilibrium lapse rates in their convective regions.

Hacia el consumo informado de tabaco en México: efecto de las advertencias con pictogramas en población fumadora

PubMed Central

Thrasher, James F; Pérez-Hernández, Rosaura; Arillo-Santillán, Edna; Barrientos-Gutiérrez, Inti

2015-01-01

Resumen Objetivo Evaluar el efecto de las advertencias sanitarias (AS) con pictogramas en las cajetillas de tabaco en adultos fumadores. Material y métodos Cohorte de fumadores con representatividad poblacional de siete ciudades mexi canas, antes (2010) y después (2011) de la implementación de AS con pictogramas (ASP). Para determinar el cambio en las variables sobre el impacto cognitivo y conductual de las advertencias, se estimaron modelos bivariados y ajustados de ecuaciones de estimación generalizada. En el Segundo levantamiento (2011), se estimaron modelos para determiner los factores que se asocian con el reporte de recordar cada advertencia que había entrado al mercado, además de los factores asociados con el autorreporte del impacto de cada advertencia vigente. Resultados Se observaron incrementos importantes de 2010 a 2011 en los conocimientos sobre los riesgos de fumar, los componentes tóxicos del tabaco y el número telefónico para recibir consejos sobre dejar de fumar. La recordación e impacto de las primeras advertencias con pictogramas parecen ser amplios y equitativos a través de la población fumadora. En comparación con 2010, un mayor nivel de ex fumadores entrevistados en 2011 reportaron que las advertencias habían influido mucho en dejar de fumar (RM=2.44, 95% IC 1.27–4.72). Conclusiones Las AS con pictogramas han logrado un impacto importante en el conocimiento y conducta, información relevante para la población y en tomadores de decisiones. PMID:22689162

The Ratio of Ortho- to Para-H2 in Photodissociation Regions

NASA Technical Reports Server (NTRS)

Sternberg, Amiel; Neufeld, David A.

1999-01-01

We discuss the ratio of ortho- to para-H2 in photodissociation regions (PDRs). We draw attention to an apparent confusion in the literature between the ortho-to-para ratio of molecules in FUV-pumped vibrationally excited states and the total H2 ortho-to-para abundance ratio. These ratios are not the same because the process of FUV pumping of fluorescent H2 emission in PDRs occurs via optically thick absorption lines. Thus gas with an equilibrium ratio of ortho- to para-H2 equal to 3 will yield FUV-pumped vibrationally excited ortho-to-para ratios smaller than 3, because the ortho-H2 pumping rates are preferentially reduced by optical depth effects. Indeed, if the ortho and para pumping lines are on the "square root" part of the curve of growth, then the expected ratio of ortho and para vibrational line strengths is 3(sup 1/2) approximately 1.7, close to the typically observed value. Thus, contrary to what has sometimes been stated in the literature, most previous measurements of the ratio of ortho- to para-H2 in vibrationally excited states are entirely consistent with a total ortho-to-para ratio of 3, the equilibrium value for temperatures greater than 200 K. We present an analysis and several detailed models that illustrate the relationship between the total ratios of ortho- to para-H2 and the vibrationally excited ortho-to-para ratios in PDRs. Recent Infrared Space Observatory measurements of pure rotational and vibrational H2 emissions from the PDR in the star-forming region S140 provide strong observational support for our conclusions.

Towards a double field theory on para-Hermitian manifolds

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vaisman, Izu

In a previous paper, we have shown that the geometry of double field theory has a natural interpretation on flat para-Kähler manifolds. In this paper, we show that the same geometric constructions can be made on any para-Hermitian manifold. The field is interpreted as a compatible (pseudo-)Riemannian metric. The tangent bundle of the manifold has a natural, metric-compatible bracket that extends the C-bracket of double field theory. In the para-Kähler case, this bracket is equal to the sum of the Courant brackets of the two Lagrangian foliations of the manifold. Then, we define a canonical connection and an action ofmore » the field that correspond to similar objects of double field theory. Another section is devoted to the Marsden-Weinstein reduction in double field theory on para-Hermitian manifolds. Finally, we give examples of fields on some well-known para-Hermitian manifolds.« less

23 CFR 772.17 - Traffic noise prediction.

Code of Federal Regulations, 2010 CFR

2010-04-01

..._federal_regulations/ibr_locations.html. These documents are available for copying and inspection at the... URL: http://www.trafficnoisemodel.org/main.html. (b) In predicting noise levels and assessing noise...

36 CFR 1238.5 - What publications are incorporated by reference in this part?

Code of Federal Regulations, 2014 CFR

2014-07-01

... Stored Silver-Gelatin Microforms for Evidence of Deterioration, January 22, 1990, IBR approved for § 1238... Materials—Processed silver-gelatin type black-and-white films—Specifications for stability, February 15...

36 CFR 1238.5 - What publications are incorporated by reference in this part?

Code of Federal Regulations, 2011 CFR

2011-07-01

... Stored Silver-Gelatin Microforms for Evidence of Deterioration, January 22, 1990, IBR approved for § 1238... Materials—Processed silver-gelatin type black-and-white films—Specifications for stability, February 15...

36 CFR 1238.5 - What publications are incorporated by reference in this part?

Code of Federal Regulations, 2012 CFR

2012-07-01

... Stored Silver-Gelatin Microforms for Evidence of Deterioration, January 22, 1990, IBR approved for § 1238... Materials—Processed silver-gelatin type black-and-white films—Specifications for stability, February 15...

47 CFR 80.179 - Unattended operation.

Code of Federal Regulations, 2010 CFR

2010-10-01

... operating as part of the Automated Maritime Telecommunications System (AMTS), an automated multi-station....archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. The ITU-R Recommendations can...

Para-nitrobenzyl esterases with enhanced activity in aqueous and nonaqueous media

DOEpatents

Arnold, F.H.; Moore, J.C.

1999-05-25

A method is disclosed for isolating and identifying modified para-nitrobenzyl esterases which exhibit improved stability and/or esterase hydrolysis activity toward selected substrates and under selected reaction conditions relative to the unmodified para-nitrobenzyl esterase. The method involves preparing a library of modified para-nitrobenzyl esterase nucleic acid segments (genes) which have nucleotide sequences that differ from the nucleic acid segment which encodes for unmodified para-nitrobenzyl esterase. The library of modified para-nitrobenzyl nucleic acid segments is expressed to provide a plurality of modified enzymes. The clones expressing modified enzymes are then screened to identify which enzymes have improved esterase activity by measuring the ability of the enzymes to hydrolyze the selected substrate under the selected reaction conditions. Specific modified para-nitrobenzyl esterases are disclosed which have improved stability and/or ester hydrolysis activity in aqueous or aqueous-organic media relative to the stability and/or ester hydrolysis activity of unmodified naturally occurring para-nitrobenzyl esterase. 43 figs.

Para-nitrobenzyl esterases with enhanced activity in aqueous and nonaqueous media

DOEpatents

Arnold, Frances H.; Moore, Jeffrey C.

1998-01-01

A method for isolating and identifying modified para-nitrobenzyl esterases which exhibit improved stability and/or esterase hydrolysis activity toward selected substrates and under selected reaction conditions relative to the unmodified para-nitrobenzyl esterase. The method involves preparing a library of modified para-nitrobenzyl esterase nucleic acid segments (genes) which have nucleotide sequences that differ from the nucleic acid segment which encodes for unmodified para-nitrobenzyl esterase. The library of modified para-nitrobenzyl nucleic acid segments is expressed to provide a plurality of modified enzymes. The clones expressing modified enzymes are then screened to identify which enzymes have improved esterase activity by measuring the ability of the enzymes to hydrolyze the selected substrate under the selected reaction conditions. Specific modified para-nitrobenzyl esterases are disclosed which have improved stability and/or ester hydrolysis activity in aqueous or aqueous-organic media relative to the stability and/or ester hydrolysis activity of unmodified naturally occurring para-nitrobenzyl esterase.

Para-nitrobenzyl esterases with enhanced activity in aqueous and nonaqueous media

DOEpatents

Arnold, Frances H.; Moore, Jeffrey C.

1999-01-01

A method for isolating and identifying modified para-nitrobenzyl esterases which exhibit improved stability and/or esterase hydrolysis activity toward selected substrates and under selected reaction conditions relative to the unmodified para-nitrobenzyl esterase. The method involves preparing a library of modified para-nitrobenzyl esterase nucleic acid segments (genes) which have nucleotide sequences that differ from the nucleic acid segment which encodes for unmodified para-nitrobenzyl esterase. The library of modified para-nitrobenzyl nucleic acid segments is expressed to provide a plurality of modified enzymes. The clones expressing modified enzymes are then screened to identify which enzymes have improved esterase activity by measuring the ability of the enzymes to hydrolyze the selected substrate under the selected reaction conditions. Specific modified para-nitrobenzyl esterases are disclosed which have improved stability and/or ester hydrolysis activity in aqueous or aqueous-organic media relative to the stability and/or ester hydrolysis activity of unmodified naturally occurring para-nitrobenzyl esterase.

Para-nitrobenzyl esterases with enhanced activity in aqueous and nonaqueous media

DOEpatents

Arnold, F.H.; Moore, J.C.

1998-04-21

A method is disclosed for isolating and identifying modified para-nitrobenzyl esterases. These enzymes exhibit improved stability and/or esterase hydrolysis activity toward selected substrates and under selected reaction conditions relative to the unmodified para-nitrobenzyl esterase. The method involves preparing a library of modified para-nitrobenzyl esterase nucleic acid segments (genes) which have nucleotide sequences that differ from the nucleic acid segment which encodes for unmodified para-nitrobenzyl esterase. The library of modified para-nitrobenzyl nucleic acid segments is expressed to provide a plurality of modified enzymes. The clones expressing modified enzymes are then screened to identify which enzymes have improved esterase activity by measuring the ability of the enzymes to hydrolyze the selected substrate under the selected reaction conditions. Specific modified para-nitrobenzyl esterases are disclosed which have improved stability and/or ester hydrolysis activity in aqueous or aqueous-organic media relative to the stability and/or ester hydrolysis activity of unmodified naturally occurring para-nitrobenzyl esterase. 43 figs.

Amyris, Inc. Integrated Biorefinery Project Summary Final Report - Public Version

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gray, David; Sato, Suzanne; Garcia, Fernando

The Amyris pilot-scale Integrated Biorefinery (IBR) leveraged Amyris synthetic biology and process technology experience to upgrade Amyris’s existing Emeryville, California pilot plant and fermentation labs to enable development of US-based production capabilities for renewable diesel fuel and alternative chemical products. These products were derived semi-synthetically from high-impact biomass feedstocks via microbial fermentation to the 15-carbon intermediate farnesene, with subsequent chemical finishing to farnesane. The Amyris IBR team tested and provided methods for production of diesel and alternative chemical products from sweet sorghum, and other high-impact lignocellulosic feedstocks, at pilot scale. This enabled robust techno-economic analysis (TEA), regulatory approvals, and amore » basis for full-scale manufacturing processes and facility design.« less

Study of the thermal-induced intensity balanced Nd:GdVO4 microchip dual-frequency laser

NASA Astrophysics Data System (ADS)

Cai, Meiling; Hu, Miao; Zhou, Xuefang; Lu, Yang; Zeng, Ran; Li, Qiliang; Wei, Yizhen

2018-01-01

The intensity balance ratio (IBR) tuning mechanism of Nd:GdVO4 monolithic microchip dual-frequency laser (DFL) is presented. The intensity balanced DFL signals are obtained by precisely controlling the heat sink temperature of the Nd:GdVO4 crystal. In experiments, the DFL signal with frequency separation at 64 GHz and IBR above 0.99 is realized with the temperature at 47.6 °C. The other balanced intensity distribution can be reached at -0.9 °C before mode hopping. Moreover, utilizing the fluorescence spectrum and the intensity balance points of Nd:GdVO4 DFL, we obtain the temperature difference between internal and external of Nd:GdVO4 crystal ΔT = 24.0 °C.

Para-hydrogen perspectives in hyperpolarized NMR.

PubMed

Glöggler, Stefan; Colell, Johannes; Appelt, Stephan

2013-10-01

The first instance of para-hydrogen induced polarization (PHIP) in an NMR experiment was serendipitously observed in the 1980s while investigating a hydrogenation reaction (Seldler et al., 1983; Bowers and Weitekamp, 1986, 1987; Eisenschmid et al., 1987) [1-4]. Remarkably a theoretical investigation of the applicability of para-hydrogen as a hyperpolarization agent was being performed in the 1980's thereby quickly providing a theoretical basis for the PHIP-effect (Bowers and Weitekamp, 1986) [2]. The discovery of signal amplification by a non-hydrogenating interaction with para-hydrogen has recently extended the interest to exploit the PHIP effect, as it enables investigation of compounds without structural alteration while retaining the advantages of spectroscopy with hyperpolarized compounds [5]. In this article we will place more emphasis of the future applications of the method while only briefly discussing the efforts that have been made in the understanding of the phenomenon and the development of the method so far. Copyright © 2013 Elsevier Inc. All rights reserved.

Mass Ejection from Old and Young Stars and the Sun

NASA Astrophysics Data System (ADS)

Jatenco-Pereira, V.; Opher, R.

1990-11-01

RESUMEN. Para poder explicar: 1) la enorme cantidad de perdida de masa y la baja velocidad asint5tica de las estrellas gigantes de o, y 2) los flujos de masa observados en protoestrellas, se sugiere un modelo para Ia perdida de masa, en donde se usa un flujo de ondas de Alfvencomo un mecanismo de aceleraci6n para los vientos de estrellas de tipo y vientos en protoestrellas. Se estudian los mecanismos de disipaci5n de las ondas de Alfven: los amortiguamientos no lineal, de superficie reso- nante y turbulento. En nuestro modelo se usa una divergente A(r) = A(R0) (r/r0)5 (donde A(r) es el area a una distancia radial r, y (A(r)/r2)max/(A(ro)/r02 - 10). Tambien se sugiere un modelo para una de hoyo coronal en el Sol. Se muestra que para satisfacer los datos observacionales en el Sol, tomando en cuenta la deposici6n del momento de las ondas de Alfven sobre el viento, se necesita: (a) una divergencia lenta en un hoyo coronal hasta una altura de 0.01 - 0.1 R seguido de (b) una divergencia rap ida de hasta una altura aproximada de 1 R . ABSTRACT: In order to explain (1) a large mass-loss rate and a small asymptotic flow speed of late-type giant stars and (2) the observed protostellar mass outflows, we suggest a model for mass loss, where we use a flux of Alfven waves as a mechanism of acceleration for late-type giant star winds and protostellar winds. We study the Alfven wave dissipation mechanisms: nonlinear damping, resonant surface damping, and turbulent damping. In our model we use a diverging geometry A(r) = A(r0) (r I r )S (where A(r) is the cross sectional area of the geometry at a radial distance r, and(A(r) I r2)max/(A(r0)/r02) = 10). We also suggest a model for a coronal hole geometry in the sun. We show that in order to satisfy the observational data of the sun, taking into account Alfven wave momentum deposition in the wind, we need: (a) a slow divergence in a coronal hole up t6 a height of 0.01 - 0.1 followed by (b) a rapid divergence up to a height of

Espectroscopia infravermelha de núcleos ativos de galáxias: resultados adicionais

NASA Astrophysics Data System (ADS)

Rodríguez Ardila, A.; Viegas, S.; Pastoria, M. G.

2003-08-01

Apresentamos resultados parciais de um levantamento espectroscópico na região do infravermelho próximo (NIR) realizado em 30 núcleos ativos de galáxias (AGN), incluindo vários objetos selecionados do catálogo PG com z de até 0.55. O objetivo é estudar a natureza do contínuo observado e as condições físicas do gas emissor. Todas as fontes de tipo 1 apresentam uma mudança na inclinação do contínuo na região de 1.2mm, associada ao término da contribuição do contínuo emitido pelo AGN e ao início da contribuição do contínuo emitido pela poeira quente atribuída ao tórus que rodeia a fonte central. O índice espectral associado à segunda contribuição varia apreciavelmente de objeto para objeto. Este resultado é comparado com distribuições espectrais de energia preditas por modelos de toroides para testar a validez do modelo unificado. A partir das linhas de FeII observado nos espectros deriva-se, pela primeira vez nessa região espectral, um template empírico de FeII para estudar a intensidade e a origem dessa emissão. A intensidade do FeII é estudada em conjunto com aquela da região visível e comparada às predições de modelos teóricos que incluem fluorescência de Lya, excitação colisional e auto-fluorescência como mecanismos dominantes de exitação. Encontra-se que os dois primeiros processos dominam na formação do espectro de FeII observado. Indicadores de avermelhamento, entre eles Brg/Pab, Pab/Pag, Pab/Pad e [FeII] 1.257/1.644 mm são utilizados para mapear a distribuição de poeira nas regiões emissoras de linhas. Encontra-se valores de extinção Av~3 associados ao último indicador e valores significativamente menores (Av~1.5) para os restantes, o que sugere que o [FeII] se forma em uma região separada da maior parte do gás emissor de linhas estreitas.

21 CFR 184.1400 - Lecithin.

Code of Federal Regulations, 2013 CFR

2013-04-01

... by reference. Copies are available from the National Academy Press, 2101 Constitution Ave. NW....archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In accordance with § 184...

21 CFR 184.1205 - Calcium hydroxide.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Constitution Ave. NW., Washington, DC 20418, or available for inspection at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In...

21 CFR 184.1272 - L-Cysteine monohydrochloride.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Constitution Ave. NW., Washington, DC 20418, or may be examined at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) The...

21 CFR 184.1317 - Garlic and its derivatives.

Code of Federal Regulations, 2012 CFR

2012-04-01

... reference. Copies may be obtained from the National Academy Press, 2101 Constitution Ave. NW., Washington.../federal_register/code_of_federal_regulations/ibr_locations.html. (c) Garlic and its derivatives are used...

21 CFR 184.1317 - Garlic and its derivatives.

Code of Federal Regulations, 2013 CFR

2013-04-01

... reference. Copies may be obtained from the National Academy Press, 2101 Constitution Ave. NW., Washington.../federal_register/code_of_federal_regulations/ibr_locations.html. (c) Garlic and its derivatives are used...

21 CFR 184.1191 - Calcium carbonate.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Constitution Ave. NW., Washington, DC 20418, or available for inspection at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In...

21 CFR 184.1135 - Ammonium bicarbonate.

Code of Federal Regulations, 2012 CFR

2012-04-01

... by reference. Copies are available from the National Academy Press, 2101 Constitution Ave. NW....archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In accordance with § 184...

21 CFR 180.30 - Brominated vegetable oil.

Code of Federal Regulations, 2012 CFR

2012-04-01

... material incorporated by reference may be obtained from the National Academy Press, 2101 Constitution Ave...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (b) The additive is...

21 CFR 184.1400 - Lecithin.

Code of Federal Regulations, 2012 CFR

2012-04-01

... by reference. Copies are available from the National Academy Press, 2101 Constitution Ave. NW....archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In accordance with § 184...

21 CFR 184.1272 - L-Cysteine monohydrochloride.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Constitution Ave. NW., Washington, DC 20418, or may be examined at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) The...

21 CFR 184.1191 - Calcium carbonate.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Constitution Ave. NW., Washington, DC 20418, or available for inspection at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In...

21 CFR 184.1205 - Calcium hydroxide.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Constitution Ave. NW., Washington, DC 20418, or available for inspection at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In...

21 CFR 184.1370 - Inositol.

Code of Federal Regulations, 2012 CFR

2012-04-01

... by reference. Copies are available from the National Academy Press, 2101 Constitution Ave. NW....archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) In accordance with § 184...

21 CFR 177.1610 - Polyethylene, chlorinated.

Code of Federal Regulations, 2014 CFR

2014-04-01

... chlorination of polyethylene conforming to the density, maximum n-hexane extractable fraction, and maximum..._federal_regulations/ibr_locations.html.), and has a 7.0 percent maximum extractable fraction in n-hexane...

36 CFR 1238.5 - What publications are incorporated by reference in this part?

Code of Federal Regulations, 2010 CFR

2010-07-01

... Recommended Practice—Microrecording of Engineering Source Documents on 35mm Microfilm, February 16, 1996, IBR... following are available from the standards reseller the Document Center Inc., 111 Industrial Road, Suite 9...

Selective detection of hyperpolarized NMR signals derived from para-hydrogen using the Only Para-hydrogen SpectroscopY (OPSY) approach.

PubMed

Aguilar, Juan A; Adams, Ralph W; Duckett, Simon B; Green, Gary G R; Kandiah, Rathika

2011-01-01

A new family of NMR pulse sequences is reported for the recording of para-hydrogen enhanced NMR spectra. This Only Para-hydrogen SpectroscopY (OPSY) approach uses coherence selection to separate hyperpolarized signals from those of fully relaxed and thermally equilibrated protons. Sequence design, performance, practical aspects and applicability to other hyperpolarization techniques are discussed. Copyright © 2010 Elsevier Inc. All rights reserved.

Study of heat and salt transport processes in the Espinheiro Channel (Ria de Aveiro)

NASA Astrophysics Data System (ADS)

Vaz, Nuno Alexandre Firmino

O principal objectivo deste trabalho consistiu no estudo da dinâmica termohalina do Canal do Espinheiro em funcao de dois forcamentos principais: mare e caudal fluvial, usando duas abordagens distintas: trabalho experimental e modelacao numerica. A propagacao da mare e o caudal fluvial do Rio Vouga sao determinantes no estabelecimento da estrutura horizontal da salinidade ao longo do canal. A estrutura termica horizontal ao longo do canal e, em grande parte, determinada pela variacao sazonal da temperatura da agua do Rio Vouga, bem como, pela variacao sazonal das condicoes meteorologicas devido a reduzida profundidade. Foi observada a formacao de fortes gradientes de salinidade (relacionados com a formacao de frentes estuarinas) numa regiao a cerca de 7-8 km da embocadura do canal, observando-se a sua migracao numa regiao de aproximadamente 1 km, dependendo do regime de mare. O balanco entre o transporte de sal de natureza advectiva e difusiva foi calculado, revelando que junto a embocadura os processos fisicos que mais contribuem para o transporte de sal sao a circulacao residual e o aprisionamento da agua em canais secundarios. Junto a foz do Rio Vouga os termos devidos a descarga fluvial e a circulacao gravitacional dominam o transporte de sal. Foi calibrado e validado um modelo numerico (Mohid, em modo 2D e 3D), sendo posteriormente utilizado para estudar a hidrologia do canal. Foi concedida particular atencao ao estudo da hidrologia em condicoes extremas de caudal fluvial e de mare. Os resultados da modelacao numerica permitiram numa primeira fase avaliar o bom desempenho do Mohid na reproducao dos escoamentos barotropicos na Ria de Aveiro, bem como na evolucao temporal das propriedades termohalinas da agua. Sob condicoes de caudal fluvial reduzido, a dinâmica do canal e essencialmente dominada pela mare. Com o aumento do caudal fluvial, a influencia da agua doce estende-se para jusante, estratificando a coluna de agua. As simulacoes 3D do Canal do

Evaluation of the performance of actions and outcomes in primary health care.

PubMed

Miclos, Paula Vitali; Calvo, Maria Cristina Marino; Colussi, Claudia Flemming

2017-01-01

The objective of this study has been to evaluate the performance of the primary care of Brazilian municipalities in relation to health actions and outcomes. This is an evaluative, cross-sectional research, with a quantitative approach, aimed at the identification of the efficiency frontier of the primary care in health actions and outcomes in Brazilian municipalities. Secondary data have been collected from the Programa Nacional de Melhoria do Acesso e da Qualidade da Atenção Básica (National Program for Improving Access and Quality of Primary Care) and the Department of Informatics of the Brazilian Unified Health System, in 2012. The data envelopment analysis tool has been used for variable returns to scale with product orientation. Municipalities have been analyzed by population size, and small municipalities have presented a high percentage of inefficiency for both models. The analysis of efficiency has indicated the existence of a higher percentage of effective municipalities in the model of health actions than in the model of health outcomes. Avaliar o desempenho da atenção básica dos municípios brasileiros quanto a ações e resultados em saúde. Pesquisa avaliativa, transversal, com abordagem quantitativa, para identificar a fronteira de eficiência da atenção básica em ações e resultados em saúde nos municípios brasileiros. Foi realizada coleta de dados secundários a partir do Programa Nacional de Melhoria do Acesso e da qualidade da Atenção Básica e do Departamento de Informática do Sistema Único de Saúde, no ano de 2012. Utilizou-se a ferramenta análise envoltória de dados para retornos variáveis de escala com orientação para produto. Os municípios foram analisados por porte populacional e verificou-se que para ambos os modelos, os municípios de pequeno porte apresentaram alto percentual de ineficiência. A análise da eficiência indicou a existência de um percentual maior de municípios eficientes no modelo de ações em sa

Physical Biologycal Interactions Controlling Larvae Dispersion: Application to Regions in the Neighbourhood of the Estuaries of North Portugal

NASA Astrophysics Data System (ADS)

Almeida, Martinho Marta

Um modelo numerico tridimensional oceânico foi usado para estudar a influencia das condicoes fisicas na dispersao e recrutamento de larvas com migracao vertical diaria (MVD) activa na plataforma continental noroeste de Portugal. As primeiras simulacoes foram forcadas por mares e verificou-se que a interaccao entre MVD e correntes de mare nao e importante para o transporte de larvas na plataforma continental oeste portuguesa. O trabalho realizado com forcamento de mares incrementou o presente conhecimento da dinâmica da mare na regiao. A analise da variacao vertical dos parâmetros das elipses de mare mostra uma separacao clara entre os harmonicos diurnos e semi-diurnos, e entre a circulacao oceânica quase barotropica e as correntes com dependencia vertical na plataforma. Desprezando a interaccao entre MVD e as mares o proximo passo foi a construcao e validacao dum modelo realistico forcado por fluxos atmosfera-oceano, capaz de reproduzir as correntes dominantes, geradas pelo vento, na plataforma continental. Na configuracao criada a MVD das larvas foi simulada com quatro cenarios de distribuicao e migracao vertical. Foram feitas duas simulacoes, uma para o final do Inverno e outra para a Primavera, abrangendo os meses de Fevereiro a Abril e Abril a Junho de 2002. Estes periodos foram escolhidos pois exibem diferentes regimes de vento, nao favoravel e favoravel ao afloramento costeiro. Os resultados mostram que as particulas com MVD sofreram maior retencao na plataforma continental interna durante condicoes de afloramento do que em qualquer outra combinacao de cenario de migracao e regime de vento. Na costa noroeste da Peninsula Iberica, que nao exibe irregularidades topograficas que poderiam criar areas de concentracao e retencao, a MVD pode constituir um mecanismo importante para evitar a dispersao de larvas em direccao ao mar aberto. None

10 CFR 431.15 - Materials incorporated by reference.

Code of Federal Regulations, 2010 CFR

2010-01-01

....03, IBR approved for § 431.12. (2) Institute of Electrical and Electronics Engineers, Inc., Standard...) Copies of IEEE Standard 112-1996 can be obtained from the Institute of Electrical and Electronics...

21 CFR 173.228 - Ethyl acetate.

Code of Federal Regulations, 2012 CFR

2012-04-01

... incorporated by reference. 1 Copies may be obtained from: National Academy Press, 2101 Constitution Ave. NW.../federal_register/code_of_federal_regulations/ibr_locations.html. (b) The additive is used in accordance...

21 CFR 184.1143 - Ammonium sulfate.

Code of Federal Regulations, 2012 CFR

2012-04-01

... reference. Copies may be obtained from the National Academy Press, 2101 Constitution Ave. NW., Washington.../federal_register/code_of_federal_regulations/ibr_locations.html. (c) The ingredient is used as a dough...

21 CFR 184.1141b - Ammonium phosphate, dibasic.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., 2101 Constitution Ave. NW., Washington, DC 20418, or available for inspection at the National Archives... 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr...

21 CFR 184.1081 - Propionic acid.

Code of Federal Regulations, 2012 CFR

2012-04-01

..., 2101 Constitution Ave. NW., Washington, DC 20418, or available for inspection at the National Archives... 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr...

21 CFR 173.228 - Ethyl acetate.

Code of Federal Regulations, 2013 CFR

2013-04-01

... incorporated by reference. 1 Copies may be obtained from: National Academy Press, 2101 Constitution Ave. NW.../federal_register/code_of_federal_regulations/ibr_locations.html. (b) The additive is used in accordance...

49 CFR 572.90 - Incorporation by reference.

Code of Federal Regulations, 2010 CFR

2010-10-01

... of the Federal Register approved that materials incorporated by reference in accordance with 5 U.S.C...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (b) The incorporated...

49 CFR 236.909 - Minimum performance standard.

Code of Federal Regulations, 2010 CFR

2010-10-01

...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html; (ii) The product is... exposure must be expressed as total train miles traveled per year over the relevant railroad infrastructure...

7 CFR 1755.200 - RUS standard for splicing copper and fiber optic cables.

Code of Federal Regulations, 2013 CFR

2013-01-01

.../code_of_federal_regulations/ibr_locations.html. Copies are available from NFPA, Batterymarch Park..., depending on the site logistics. However, the required slack is seldom less than 15 meters (50 feet). The...

7 CFR 1755.200 - RUS standard for splicing copper and fiber optic cables.

Code of Federal Regulations, 2014 CFR

2014-01-01

.../code_of_federal_regulations/ibr_locations.html. Copies are available from NFPA, Batterymarch Park..., depending on the site logistics. However, the required slack is seldom less than 15 meters (50 feet). The...

7 CFR 1755.200 - RUS standard for splicing copper and fiber optic cables.

Code of Federal Regulations, 2012 CFR

2012-01-01

.../code_of_federal_regulations/ibr_locations.html. Copies are available from NFPA, Batterymarch Park..., depending on the site logistics. However, the required slack is seldom less than 15 meters (50 feet). The...

21 CFR 173.45 - Polymaleic acid and its sodium salt.

Code of Federal Regulations, 2011 CFR

2011-04-01

... HUMAN CONSUMPTION Polymer Substances and Polymer Adjuvants for Food Treatment § 173.45 Polymaleic acid..._regulations/ibr_locations.html. (b) The additives may be used, individually or together, in the processing of...

Análise da medição do raio solar em ultravioleta

NASA Astrophysics Data System (ADS)

Saraiva, A. C. V.; Giménez de Castro, C. G.; Costa, J. E. R.; Selhorst, C. L.; Simões, P. J. A.

2003-08-01

A medição acurada do raio solar em qualquer banda do espectro eletromagnético é de relevância na formulação e calibração de modelos da estrutura e atmosfera solar. Esses modelos atribuem emissão do contínuo do Sol calmo em microondas à mesma região da linha Ha do Hell. Apresentamos a medição do raio solar em UV com imagens do EIT (Extreme Ultraviolet Image Telescope) entre 1996 e 2002, no comprimento de onda 30,9 nm (Ha do Hell), que se forma na região de transição/cromosfera solar. A técnica utilizada para o cálculo do raio UV foi baseada na transformada Wavelet B3spline. Fizemos um banco de dados com 1 imagem por dia durante o período citado. Obtivemos como resultado o raio médio da ordem de 975.61" e uma diminuição do mesmo para o período citado variando em média -0,45" /ano. Comparamos estes dados com os valores obtidos pelo ROI (Radio Observatório de Itapetinga) em 22/48 GHz e Nobeyama Radio Heliograph em 17 GHz mostrando que os raios médios são muito próximos o que indica que a região de formação nessas freqüências é a mesma conforme os modelos. Comparamos os resultados também com outros índices de atividade solar.

Characterization of phytase enzymes as feed additive for poultry and feed

NASA Astrophysics Data System (ADS)

Lamid, M.; Al-Arif, A.; Asmarani, O.; Warsito, S. H.

2018-04-01

One of the obstacles to utilizing rice bran as feed is the presence of antinutrition in the form of phytic acid which binds in minerals to form complex compounds with P, Mg, Mn, Fe, Zn, Ca. Phytic acid and its salts are the main forms of P, Mg, Mn, Fe, Zn, Ca deposits contained in cereals, legume and grains, about 60-90% of total minerals P, Mg, Mn, Fe, Zn, Ca in the form of phytic acid or phytate salts. Phytate is one of the enzymes belonging to the phosphatase group capable of hydrolyzing phytate compounds of myo-inositol (1,2,3,4,5,6) hexsa phosphatase into myo-inositol and organic phosphat. The aim of this study was to obtain characterization of phytase enzymes from isolate Actinobacillus sp., Bacillus pumilus, Bacillus vallimortis and IBR-1. Determination of phytase activity and the absorbance was measured using a UV-Vis spectrophotometer at a wavelength of 392 nm. The result of Actinobacillus sp, Bacillus pumilus, Bacillus vallimortis, IBR-1 each having optimum temperature were 50°C, 40°C, 45°C, 45°C, and optimum pH were 4, 4, 5.5. Bacteria especially Actinobacillus sp, Bacillus pumilus, Bacillus vallimortis, IBR-1 are proven capable of producing the high enough phytase enzymes required for mineral availability for livestock and fish.

40 CFR 600.011-93 - Reference materials.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Natural Gas By Gas Chromatography, IBR approved for §§ 600.113-93, 600.113-08. (c) SAE Material. The... obtained from Society of Automotive Engineers World Headquarters, 400 Commonwealth Dr., Warrendale, PA...

The NHV rehabilitation services program improves long-term physical functioning in survivors of the 2008 Sichuan earthquake: a longitudinal quasi experiment.

PubMed

Zhang, Xia; Reinhardt, Jan D; Gosney, James E; Li, Jianan

2013-01-01

Long-term disability following natural disasters significantly burdens survivors and the impacted society. Nevertheless, medical rehabilitation programming has been historically neglected in disaster relief planning. 'NHV' is a rehabilitation services program comprised of non-governmental organizations (NGOs) (N), local health departments (H), and professional rehabilitation volunteers (V) which aims to improve long-term physical functioning in survivors of the 2008 Sichuan earthquake. We aimed to evaluate the effectiveness of the NHV program. 510 of 591 enrolled earthquake survivors participated in this longitudinal quasi-experimental study (86.3%). The early intervention group (NHV-E) consisted of 298 survivors who received institutional-based rehabilitation (IBR) followed by community-based rehabilitation (CBR); the late intervention group (NHV-L) was comprised of 101 survivors who began rehabilitation one year later. The control group of 111 earthquake survivors did not receive IBR/CBR. Physical functioning was assessed using the Barthel Index (BI). Data were analyzed with a mixed-effects Tobit regression model. Physical functioning was significantly increased in the NHV-E and NHV-L groups at follow-up but not in the control group after adjustment for gender, age, type of injury, and time to measurement. We found significant effects of both NHV (11.14, 95% CI 9.0-13.3) and sponaneaous recovery (5.03; 95% CI 1.73-8.34). The effect of NHV-E (11.3, 95% CI 9.0-13.7) was marginally greater than that of NHV-L (10.7, 95% CI 7.9-13.6). It could, however, not be determined whether specific IBR or CBR program components were effective since individual component exposures were not evaluated. Our analysis shows that the NHV improved the long-term physical functioning of Sichuan earthquake survivors with disabling injuries. The comprehensive rehabilitation program benefitted the individual and society, rehabilitation services in China, and international rehabilitation

40 CFR 1066.710 - Reference materials.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Dynamometer Simulation Using Coastdown Techniques, Revised March 2010, IBR approved for §§ 1066.301(b) and..., 100 Bureau Drive, Stop 1070, Gaithersburg, MD 20899-1070, (301) 975-6478, http://www.nist.gov, or...

40 CFR 1066.710 - Reference materials.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Dynamometer Simulation Using Coastdown Techniques, Revised March 2010, IBR approved for §§ 1066.301(b) and..., 100 Bureau Drive, Stop 1070, Gaithersburg, MD 20899-1070, (301) 975-6478, http://www.nist.gov, or...

50 CFR 622.6 - Vessel and gear identification.

Code of Federal Regulations, 2012 CFR

2012-10-01

.... (due east of the NASA Vehicle Assembly Building, Cape Canaveral, FL), or a sea bass pot on board a....archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. Copies of the incorporated...

76 FR 38992 - Approval and Promulgation of Air Quality Implementation Plans; Pennsylvania; Update to Materials...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-05

... Definitions 5/24/10 12/28/10, 75 FR 81555... Addition of four new definitions: Exterior panels, interior panels, flat wood panel coating, and tileboard. See Part III of the IBR document. * * * * * * Part E...

40 CFR 89.6 - Reference materials.

Code of Federal Regulations, 2014 CFR

2014-07-01

... July 1, 2009), Standard Test Method for Kinematic Viscosity of Transparent and Opaque Liquids (the Calculation of Dynamic Viscosity), IBR approved for appendix A to subpart D. (6) ASTM D613-95, Standard Test...

40 CFR 89.6 - Reference materials.

Code of Federal Regulations, 2012 CFR

2012-07-01

... July 1, 2009), Standard Test Method for Kinematic Viscosity of Transparent and Opaque Liquids (the Calculation of Dynamic Viscosity), IBR approved for appendix A to subpart D. (6) ASTM D613-95, Standard Test...

40 CFR 89.6 - Reference materials.

Code of Federal Regulations, 2013 CFR

2013-07-01

... July 1, 2009), Standard Test Method for Kinematic Viscosity of Transparent and Opaque Liquids (the Calculation of Dynamic Viscosity), IBR approved for appendix A to subpart D. (6) ASTM D613-95, Standard Test...

40 CFR 49.5511 - Identification of plan.

Code of Federal Regulations, 2012 CFR

2012-07-01

...-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations... Director, GRIC DEQ, to Deborah Jordan, Air Division Director, EPA Region 9, Re: Gila River Indian Community...

40 CFR 49.5511 - Identification of plan.

Code of Federal Regulations, 2014 CFR

2014-07-01

...-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations... Director, GRIC DEQ, to Deborah Jordan, Air Division Director, EPA Region 9, Re: Gila River Indian Community...

40 CFR 49.5511 - Identification of plan.

Code of Federal Regulations, 2013 CFR

2013-07-01

...-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations... Director, GRIC DEQ, to Deborah Jordan, Air Division Director, EPA Region 9, Re: Gila River Indian Community...

40 CFR 49.5511 - Identification of plan.

Code of Federal Regulations, 2011 CFR

2011-07-01

...-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations... Director, GRIC DEQ, to Deborah Jordan, Air Division Director, EPA Region 9, Re: Gila River Indian Community...

ORTHO-PARA SELECTION RULES IN THE GAS-PHASE CHEMISTRY OF INTERSTELLAR AMMONIA

DOE Office of Scientific and Technical Information (OSTI.GOV)

Faure, A.; Hily-Blant, P.; Le Gal, R.

The ortho-para chemistry of ammonia in the cold interstellar medium is investigated using a gas-phase chemical network. Branching ratios for the primary reaction chain involved in the formation and destruction of ortho- and para-NH{sub 3} were derived using angular momentum rules based on the conservation of the nuclear spin. We show that the 'anomalous' ortho-to-para ratio of ammonia ({approx}0.7) observed in various interstellar regions is in fact consistent with nuclear spin selection rules in a para-enriched H{sub 2} gas. This ratio is found to be independent of temperature in the range 5-30 K. We also predict an ortho-to-para ratio ofmore » {approx}2.3 for NH{sub 2}. We conclude that a low ortho-to-para ratio of H{sub 2} naturally drives the ortho-to-para ratios of nitrogen hydrides below the statistical values.« less

Violación del Principio de Equivalencia en Teorías con Dilatón de Cuerdas

NASA Astrophysics Data System (ADS)

Landau, S. J.; Sisterna, P. D.; Vucetich, H.

Se estudian las violaciones al Principio de Equivalencia en Teorías con Dilatón de Cuerdas. En estos modelos, algunas de las constantes fundamentales dependen del espacio y del tiempo. Se muestra que los experimentos de caída libre no tienen aún precisión como para poner límites a los parámetros de la teoría.

Readiness to tackle chronicity in Spanish health care organisations: a two-year experience with the Instrumento de Evaluación de Modelos de Atención ante la Cronicidad/Assessment of Readiness for Chronicity in Health Care Organisations instrument

PubMed Central

Mira, José Joaquín; Fernández-Cano, Paloma; Contel, Joan Carlos; Guilabert-Mora, Mercedes; Solas-Gaspar, Olga

2015-01-01

Introduction: The Instrumento de Evaluación de Modelos de Atención ante la Cronicidad/Assessment of Readiness for Chronicity in Health Care Organisations instrument was developed to implement the conceptual framework of the Chronic Care Model in the Spanish national health system. It has been used to assess readiness to tackle chronicity in health care organisations. In this study, we use self-assessments at macro-, meso- and micro-management levels to (a) describe the two-year experience with the Instrumento de Evaluación de Modelos de Atención ante la Cronicidad/Assessment of Readiness for Chronicity in Health Care Organisations tool in Spain and (b) assess the validity and reliability of this instrument. Methods: The results from 55 organisational self-assessments were included and described. In addition to that, the internal consistency, reliability and construct validity of Instrumento de Evaluación de Modelos de Atención ante la Cronicidad/Assessment of Readiness for Chronicity in Health Care Organisations were examined using Cronbach's alpha, the Spearman–Brown coefficient and factorial analysis. Results: The obtained scores reflect opportunities for improvement in all dimensions of the instrument. Cronbach's alpha ranged between 0.90 and 0.95 and the Spearman–Brown coefficient ranged between 0.77 and 0.94. All 27 components converged in a second-order factorial solution that explained 53.8% of the total variance, with factorial saturations for the components of between 0.57 and 0.94. Conclusions: Instrumento de Evaluación de Modelos de Atención ante la Cronicidad/Assessment of Readiness for Chronicity in Health Care Organisations is an instrument that allows health care organisations to perform self-assessments regarding their readiness to tackle chronicity and to identify areas for improvement in chronic care. PMID:27118958

Readiness to tackle chronicity in Spanish health care organisations: a two-year experience with the Instrumento de Evaluación de Modelos de Atención ante la Cronicidad/Assessment of Readiness for Chronicity in Health Care Organisations instrument.

PubMed

Mira, José Joaquín; Nuño-Solinís, Roberto; Fernández-Cano, Paloma; Contel, Joan Carlos; Guilabert-Mora, Mercedes; Solas-Gaspar, Olga

2015-01-01

The Instrumento de Evaluación de Modelos de Atención ante la Cronicidad/Assessment of Readiness for Chronicity in Health Care Organisations instrument was developed to implement the conceptual framework of the Chronic Care Model in the Spanish national health system. It has been used to assess readiness to tackle chronicity in health care organisations. In this study, we use self-assessments at macro-, meso- and micro-management levels to (a) describe the two-year experience with the Instrumento de Evaluación de Modelos de Atención ante la Cronicidad/Assessment of Readiness for Chronicity in Health Care Organisations tool in Spain and (b) assess the validity and reliability of this instrument. The results from 55 organisational self-assessments were included and described. In addition to that, the internal consistency, reliability and construct validity of Instrumento de Evaluación de Modelos de Atención ante la Cronicidad/Assessment of Readiness for Chronicity in Health Care Organisations were examined using Cronbach's alpha, the Spearman-Brown coefficient and factorial analysis. The obtained scores reflect opportunities for improvement in all dimensions of the instrument. Cronbach's alpha ranged between 0.90 and 0.95 and the Spearman-Brown coefficient ranged between 0.77 and 0.94. All 27 components converged in a second-order factorial solution that explained 53.8% of the total variance, with factorial saturations for the components of between 0.57 and 0.94. Instrumento de Evaluación de Modelos de Atención ante la Cronicidad/Assessment of Readiness for Chronicity in Health Care Organisations is an instrument that allows health care organisations to perform self-assessments regarding their readiness to tackle chronicity and to identify areas for improvement in chronic care.

La Enseñanza/Aprendizaje del Modelo Sol-Tierra Análisis de la Situación Actual y Propuesta de Mejora Para la Formación de los Futuros Profesores de Primaria

NASA Astrophysics Data System (ADS)

Martínez Sebastià, Bernat

2004-12-01

This work is an extened summary of the autor's PhD thesis. It deals with the teaching of astronomy (day/night, seasons) in primary school. At first, students teachers' undestanding of astronomical concepts related to Sun-Earth system have been analysed. Taking into account the results of the previous analysis and using a socio-constructivist approach a teaching sequence has been designed. This sequence has been tested with different groups of students teachers showing an improvement in their undestanding of elementary astronomical concepts. El trabajo que presentamos es un resumen extenso de la tesis doctoral del autor. El enfoque utilizado ha sido tratar de ligar la investigación sobre las ideas, razonamientos y obstáculos de los profesores de primaria con la planificación de la enseñanza del modelo Sol-Tierra que permite explicar el ciclo día/noche y las estaciones. En primer lugar, se ha procedido a realizar un análisis crítico de los resultados que se obtienen en el aprendizaje de los contenidos astronómicos en la enseñanza habitual. En segundo lugar se ha diseñado un curriculum potencialmente superador de esta situación desde una orientación que concibe la enseñanza y el aprendizaje como un proceso de construcción de conocimientos en una estructura problematizada. Finalmente, esta secuencia didáctica ha sido experimentada con diferentes grupos de estudiantes de magisterio, mostrando una mejora relevante en la comprensión de los conceptos astronómicos fundamentales.

33 CFR 154.106 - Incorporation by reference: Where can I get a copy of the publications incorporated by reference...

Code of Federal Regulations, 2013 CFR

2013-07-01

...) IEC 309-1—Plugs, Socket-Outlets and Couplers for Industrial Purposes: Part 1, General Requirements, 1979, IBR approved for § 154.812. (2) IEC 309-2—Plugs, Socket-Outlets and Couplers for Industrial...

77 FR 54937 - International Mail Postal Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-06

... United States for recycling, refurbishment, repair, or value-added processing. Notice at 5. \\3\\ The IBRS... to take effect 1 day later, on September 15, 2012, for a period of 1 year, unless terminated earlier...

47 CFR 76.602 - Incorporation by reference.

Code of Federal Regulations, 2011 CFR

2011-10-01

... MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Technical Standards § 76.602 Incorporation by reference. (a... System,” 2003, IBR approved for § 76.640. (4) ANSI/SCTE 54 2003 (formerly DVS 241), “Digital Video...

On acoplamento mecânico entre a antena e o transdutor no detector de ondas gravitacionais Mario Schenberg

NASA Astrophysics Data System (ADS)

Melo, J. L.; Aguiar, O. D.; Velloso, W. F., Jr.; Lucena, A. U.

2003-08-01

O detector de ondas gravitacionais MARIO SCHENBERG consistirá de uma massa esférica de cobre-alumínio de 1150kg resfriada a 4K, sobre a qual serão instalados 6 transdutores de nióbio. Com estes trandutores pretende-se converter um possível sinal de onda gravitacional detectado em sinal elétrico, para tanto é necessário que o acoplamento mecânico entre os transdutores e a massa ressonante seja o maior possível. Isto significa que o transdutor deve ser ressonante na mesma freqüência que a antena (aproximadamente 3200Hz). Neste trabalho foi desenvolvida uma geometria para a estrutura mecânica do trandutor. Isto foi feito criando-se modelos em elementos finitos usando-se o "software" MSC/Nastran. Estes modelos criados foram analisados estaticamente (cálculo de tensões) e dinamicamente (cálculo das freqüências de ressonâncias e seus respectivos modos normais) de maneira a se obter o primeiro modo normal do transdutor em 3200Hz. A partir destes cálculos escolheu-se a melhor geometria para o transdutor. Os próximos passos do trabalho serão: usinar este transdutor em uma barra de nióbio e testá-lo à temperatura ambiente e à baixa temperatura. Após isto, pretende-se testá-lo na própria antena resfriada.

Key Nutritional Strategies to Optimize Performance in Para Athletes.

PubMed

Scaramella, Jacque; Kirihennedige, Nuwanee; Broad, Elizabeth

2018-05-01

Para athletes are a high-risk population for inadequate dietary intake leading to insufficiencies in nutrients important to athletic performance. This is partly due to minimal support and resources, especially in sport nutrition education, combined with limited prior nutrition knowledge and risks associated with different impairment types. Inadequate energy, carbohydrate, protein, iron, and vitamin D status are of particular concern in Para athletes. Assessment of these key nutrients, along with sport nutrition education, is needed to empower Para athletes with the knowledge to understand their individual nutrition needs and maximize athletic performance. Copyright © 2018 Elsevier Inc. All rights reserved.

PREVENCIÓN DEL VIH/SIDA EN LOS CIRCUITOS DE LEVANTE HSH: UNA ASIGNATURA PENDIENTE.

PubMed

Barreda, Victoria; Carballo-Dieguez, Alex; Marone, Rubén; Balán, Iván; Pando, María Ángeles; Avila, María Mercedes

2010-12-01

A partir de un relevamiento de tipo etnográfico, se describen lugares de encuentro de HSH en la Ciudad de Buenos Aires y sus prácticas sexuales. El reconocimiento de tales espacios, así como las características que asumen en ellos los encuentros sexuales entre los HSH, plantean obstáculos específicos en la adopción de comportamientos preventivos y, asimismo, generan nuevos desafíos para las actividades de prevención. Se plantean las dificultades y debates conceptuales que la misma categoría presenta, y sus consecuencias en el abordaje preventivo y teórico-metodológico para las ciencias sociales. Además, se proponen nuevos interrogantes acerca de los alcances y las limitaciones del modelo preventivo del VIH/Sida para HSH.

49 CFR 173.303 - Charging of cylinders with compressed gas in solution (acetylene).

Code of Federal Regulations, 2010 CFR

2010-10-01

... with acetylene must be successfully tested in accordance with CGA C-12. (b) Filling limits. For DOT... conform to ISO 3807-2 (IBR, see § 171.7 of this subchapter), have a homogeneous monolithic porous mass...

33 CFR 154.106 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 20, Switzerland. (1) IEC 60309-1 Plugs, Socket-Outlets and Couplers for Industrial Purposes—Part 1: General Requirements, Edition 4.2 2012-06, IBR approved for § 154.2102(b). (2) IEC 60309-2 Plugs, Socket...

40 CFR 270.6 - References.

Code of Federal Regulations, 2010 CFR

2010-07-01

... incorporations by reference were approved by the Director of the Federal Register pursuant to 5 U.S.C. 552(a) and.../federal_register/code_of_federal_regulations/ibr_locations.html. (b) The following materials are available...

21 CFR 172.105 - Anoxomer.

Code of Federal Regulations, 2010 CFR

2010-04-01

...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (4) Heavy metals as lead (as Pb), not more than 10 parts per million. Arsenic (as As), not more than 3 parts per...

21 CFR 172.105 - Anoxomer.

Code of Federal Regulations, 2011 CFR

2011-04-01

...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (4) Heavy metals as lead (as Pb), not more than 10 parts per million. Arsenic (as As), not more than 3 parts per...

Probing the Superfluid Response of para-Hydrogen with a Sulfur Dioxide Dopant.

PubMed

Zeng, Tao; Guillon, Grégoire; Cantin, Joshua T; Roy, Pierre-Nicholas

2013-07-18

We recently presented the first attempt at using an asymmetric top molecule (para-water) to probe the superfluidity of nanoclusters (of para-hydrogen) [ Zeng , T. ; Li , H. ; Roy , P.-N. J. Phys. Chem. Lett. 2013 , 4 , 18 - 22 ]. Unfortunately, para-water could not be used to probe the para-hydrogen superfluid response. We now report a theoretical simulation of sulfur dioxide rotating in para-hydrogen clusters and show that this asymmetric top can serve as a genuine probe of superfluidity. With this probe, we predict that as few as four para-hydrogen molecules are enough to form a superfluid cluster, the smallest superfluid system to date. We also propose the concept of "exchange superfluid fraction" as a more precise measurement. New superfluid scenarios brought about by an asymmetric top dopant and potential experimental measurements are discussed.

49 CFR 180.205 - General requirements for requalification of specification cylinders.

Code of Federal Regulations, 2010 CFR

2010-10-01

... for steel and nickel cylinders (IBR, see § 171.7 of this subchapter); C-6.1 for seamless aluminum... neck using a steel stamp; (ii) For composite cylinders, securely affix to the cylinder a label with the...

49 CFR 180.205 - General requirements for requalification of specification cylinders.

Code of Federal Regulations, 2013 CFR

2013-10-01

... for steel and nickel cylinders (IBR, see § 171.7 of this subchapter); C-6.1 for seamless aluminum... neck using a steel stamp; (ii) For composite cylinders, securely affix to the cylinder a label with the...

49 CFR 180.205 - General requirements for requalification of specification cylinders.

Code of Federal Regulations, 2011 CFR

2011-10-01

... for steel and nickel cylinders (IBR, see § 171.7 of this subchapter); C-6.1 for seamless aluminum... neck using a steel stamp; (ii) For composite cylinders, securely affix to the cylinder a label with the...

49 CFR 180.205 - General requirements for requalification of specification cylinders.

Code of Federal Regulations, 2012 CFR

2012-10-01

... for steel and nickel cylinders (IBR, see § 171.7 of this subchapter); C-6.1 for seamless aluminum... neck using a steel stamp; (ii) For composite cylinders, securely affix to the cylinder a label with the...

45 CFR 170.299 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 19, 2012, IBR approved for § 170.202. (l) Regenstrief Institute, Inc., LOINC® c/o Medical Informatics....nih.gov/. (1) International Health Terminology Standards Development Organization Systematized....207. (2) International Health Terminology Standards Development Organisation (IHTSDO) Systematized...

40 CFR 85.2231 - On-board diagnostic test equipment requirements.

Code of Federal Regulations, 2010 CFR

2010-07-01

.../code_of_federal_regulations/ibr_locations.html. (b) The test system shall be capable of communicating..._locations.html. (d) [Reserved] [61 FR 40948, Aug. 6, 1996, as amended at 63 FR 24434, May 4, 1998; 66 FR...

33 CFR 120.120 - Incorporation by reference.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Register in accordance with 5 U.S.C. 552(a) and 1 CFR Part 51. To enforce any edition other than that...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (b) The...

40 CFR 260.11 - References.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Hydrocarbon Fuels by Bomb Calorimeter (High-Precision Method),” IBR approved for §§ 264.1033, 265.1033. (5... Methods for Preparing Refuse-Derived Fuel (RDF) Samples for Analyses of Metals,” Test Method C—Bomb, Acid...

29 CFR 1915.5 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., Quincy, MA 02269-9101: (i) NFPA 1981-2002 Standard on Open-Circuit Self-Contained Breathing Apparatus for...-, Medium-, and High-Expansion Foam, IBR approved for § 1915.507(d)(3). (xiv) NFPA 17-2002, Standard for Dry...

29 CFR 1915.5 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., Quincy, MA 02269-9101: (i) NFPA 1981-2002 Standard on Open-Circuit Self-Contained Breathing Apparatus for...-, Medium-, and High-Expansion Foam, IBR approved for § 1915.507(d)(3). (xiv) NFPA 17-2002, Standard for Dry...

29 CFR 1915.5 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-07-01

... Batterymarch Park, PO Box 9101, Quincy, MA 02269-9101: (i) NFPA 1981-2002 Standard on Open-Circuit Self... 11-2005 Standard for Low-, Medium-, and High-Expansion Foam, IBR approved for § 1915.507(d)(3). (xiv...

29 CFR 1915.5 - Incorporation by reference.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., Quincy, MA 02269-9101: (i) NFPA 1981-2002 Standard on Open-Circuit Self-Contained Breathing Apparatus for...-, Medium-, and High-Expansion Foam, IBR approved for § 1915.507(d)(3). (xiv) NFPA 17-2002, Standard for Dry...

78 FR 11699 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-19

... additional International Business Reply Service (IBRS) Competitive Contract 3 negotiated service agreement... International Business Reply Service Competitive Contract 3 Negotiated Service Agreement, February 11, 2013.... 684, Order Approving International Business Reply Service Competitive Contract 3 Negotiated Service...

46 CFR 160.010-1 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-10-01

... (Polystyrene Foam, Expanded Bead), (July 10, 1970), IBR approved for § 160.010-5 (“MIL-P-19644C”). (2) MIL-P-21929B, Military Specification, Plastic Material, Cellular Polyurethane, Foam-In-Place, Rigid (2 and 4...

Lampreys, the jawless vertebrates, contain only two ParaHox gene clusters.

PubMed

Zhang, Huixian; Ravi, Vydianathan; Tay, Boon-Hui; Tohari, Sumanty; Pillai, Nisha E; Prasad, Aravind; Lin, Qiang; Brenner, Sydney; Venkatesh, Byrappa

2017-08-22

ParaHox genes ( Gsx , Pdx , and Cdx ) are an ancient family of developmental genes closely related to the Hox genes. They play critical roles in the patterning of brain and gut. The basal chordate, amphioxus, contains a single ParaHox cluster comprising one member of each family, whereas nonteleost jawed vertebrates contain four ParaHox genomic loci with six or seven ParaHox genes. Teleosts, which have experienced an additional whole-genome duplication, contain six ParaHox genomic loci with six ParaHox genes. Jawless vertebrates, represented by lampreys and hagfish, are the most ancient group of vertebrates and are crucial for understanding the origin and evolution of vertebrate gene families. We have previously shown that lampreys contain six Hox gene loci. Here we report that lampreys contain only two ParaHox gene clusters (designated as α- and β-clusters) bearing five ParaHox genes ( Gsxα , Pdxα , Cdxα , Gsxβ , and Cdxβ ). The order and orientation of the three genes in the α-cluster are identical to that of the single cluster in amphioxus. However, the orientation of Gsxβ in the β-cluster is inverted. Interestingly, Gsxβ is expressed in the eye, unlike its homologs in jawed vertebrates, which are expressed mainly in the brain. The lamprey Pdxα is expressed in the pancreas similar to jawed vertebrate Pdx genes, indicating that the pancreatic expression of Pdx was acquired before the divergence of jawless and jawed vertebrate lineages. It is likely that the lamprey Pdxα plays a crucial role in pancreas specification and insulin production similar to the Pdx of jawed vertebrates.

Ortho- and para-hydrogen in dense clouds, protoplanets, and planetary atmospheres

NASA Technical Reports Server (NTRS)

Decampli, W. M.; Cameron, A. G. W.; Bodenheimer, P.; Black, D. C.

1978-01-01

If ortho- and para-hydrogen achieve a thermal ratio on dynamical time scales in a molecular hydrogen cloud, then the specific heat is high enough in the temperature range 35-70 K to possibly induce hydrodynamic collapse. The ortho-para ratio in many interstellar cloud fragments is expected to meet this condition. The same may have been true for the primitive solar nebula. Detailed hydrodynamic and hydrostatic calculations are presented that show the effects of the assumed ortho-para ratio on the evolution of Jupiter during its protoplanetary phase. Some possible consequences of a thermalized ortho-para ratio in the atmospheres of the giant planets are also discussed.

Cooling by conversion of para to ortho-hydrogen

NASA Technical Reports Server (NTRS)

Sherman, A. (Inventor)

1983-01-01

The cooling capacity of a solid hydrogen cooling system is significantly increased by exposing vapor created during evaporation of a solid hydrogen mass to a catalyst and thereby accelerating the endothermic para-to-ortho transition of the vapor to equilibrium hydrogen. Catalyst such as nickel, copper, iron or metal hydride gels of films in a low pressure drop catalytic reactor are suitable for accelerating the endothermic para-to-ortho conversion.

Sustainable Building in China -- A Green Leap Forward?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Diamond, Richard; Ye, Qing; Feng, Wei

2013-09-01

China is constructing new commercial buildings at an enormous rate -- roughly 2 billion square meters per year, with considerable interest and activity in green design and construction. We review the context of commercial building design and construction in China, and look at a specific project as an example of a high performance, sustainable design, the Shenzhen Institute of Building Research (IBR). The IBR building incorporates over 40 sustainable technologies and strategies, including daylighting, natural ventilation, gray-water recycling, solar-energy generation, and highly efficient Heating Ventilation and Air Conditioning (HVAC) systems. We present measured data on the performance of the building,more » including detailed analysis by energy end use, water use, and occupant comfort and satisfaction. Total building energy consumption in 2011 was 1151 MWh, with an Energy Use Intensity (EUI) of 63 kWh/m 2 (20 kBtu/ft 2), which is 61% of the mean EUI value of 103 kWh/m 2 (33 kBtu/ft 2) for similar buildings in the region. We also comment on the unique design process, which incorporated passive strategies throughout the building, and has led to high occupant satisfaction with the natural ventilation, daylighting, and green patio work areas. Lastly we present thoughts on how the design philosophy of the IBR building can be a guide for low-energy design in different climate regions throughout China and elsewhere.« less

Integrated biomarker response index used in laboratory exposure of the mussel Mytilus edulis to water accommodated fractions of crude oil

NASA Astrophysics Data System (ADS)

Yuan, Mengqi; Wang, You; Zhang, Xinxin; Hu, Shunxin; Tang, Xuexi

2017-03-01

Oil pollution is a serious environmental problem in coastal areas and to set up a quantitative evaluation method in monitoring the environmental pollution is of great importance. Individuals of Mytilus edulis, collected from the coastal area of Qingdao, were thus exposed to the water accommodated fractions (WAFs) of crude oil under controlled lab conditions. Mussels were exposed to different concentrations of WAFs for 96h acute toxicity experiment and 15d chronic toxicity experiment, a 7d restoration experiment was conducted after toxicity experiment as well. The activities of the antioxidant enzymes (CAT, GST, GPx and GR) were measured in gills of mussels. The purpose of the study was to screen out a series of sensitive biomarkers and set up an Integrated Biomarker Response index (IBR) for marine oil pollution monitoring. Results showed: (1) WAFs exposure induced the increased activities of CAT, GST, GPx and GR in gills, revealing a stimulation effect on the antioxidant system. Activities of enzymes were more significantly altered in response to higher concentrations of WAFs (2.3 and 5.0 mg.L-1) than lower concentrations (0.5 and 1.1 mg.L-1). After restoration experiment, the activities decreased to the initial levels. (2) IBR was set up base on the laboratory experiment, which showed a positive relationship with WAFs exposure concentrations. Therefore, IBR was suggested to be a potentially useful tool in assessing the oil pollution.

Assessment of health status of oysters (Crassostreagigas) exposed to environmentally relevant concentrations of Ag and Cu in brackish waters

NASA Astrophysics Data System (ADS)

Rementeria, Ane; Mikolaczyk, Mathilde; Peña, Ainhize; Lanceleur, Laurent; Blanc, Gérard; Soto, Manu; Schäfer, Jörg; Zaldibar, Beñat

2017-12-01

Human activities have altered estuarine environments leading to increased presence of different pollutants including metals. Although the implementation of new environmental policies has caused a considerable decrease in trace metal concentrations in estuaries around the Bay of Biscay, some elements such as copper (Cu) and silver (Ag) are still present in relatively high concentrations. Oysters have been widely used in environmental biomonitoring programs as sentinel organisms. Oysters Crassostrea gigas from an uncontaminated estuary were exposed to sublethal, environmentally relevant concentrations of Cu (2000 ng Cu/L) and Ag (500 ng Ag/L) during 14 days in brackish water (S = 18). A battery of cell and tissue level (exposure) biomarkers at different levels of biological complexity was applied and integrated into the Integrative Biological Response (IBR) index including: metallothionein contents, intralysosomal metal accumulation, digestive gland atrophy and digestive gland tissue integrity. Condition Index (CI) was incorporated into the IBR index as a complementary parameter that reflects the general physiological condition of oysters (organism level). Results indicated an increase in intralysosomal metal accumulation after 7 and 14 days of exposure to Ag together with an increase in the digestive epithelium atrophy and lipofuscin content after 7 days of exposure to Ag. The responses detected with the aid of biomarkers integrated in the IBR index showed higher toxicity in oysters exposed to Ag, inducing the clear onset of detoxification processes which also occurred, to a lower extent, in Cu-exposed oysters.

La Educacion Continua de Profesionales de la Salud--Un Modelo para su Desarrollo

ERIC Educational Resources Information Center

Stensland, Per G.

1974-01-01

The author suggests a framework for planning and evaluating continuing education, giving attention to the learner, his objectives, and the learning process; these components are discussed in determining the special characteristics of the continuing education of professional health workers, and a model program is presented. The article is in…

Integrated Biorefinery Project: Cooperative Research and Development Final Report, CRADA Number CRD-10-390

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chapeaux, A.; Schell, D.

2013-06-01

The Amyris-NREL CRADA is a sub-project of Amyris?s DOE-funded pilot-scale Integrated Biorefinery (IBR). The primary product of the Amyris IBR is Amyris Renewable Diesel. Secondary products will include lubricants, polymers and other petro-chemical substitutes. Amyris and its project partners will execute on a rapid project to integrate and leverage their collective expertise to enable the conversion of high-impact biomass feedstocks to these advanced, infrastructure-compatible products. The scope of the Amyris-NREL CRADA includes the laboratory development and pilot scale-up of bagasse pretreatment and enzymatic saccharification conditions by NREL for subsequent conversion of lignocellulosic sugar streams to Amyris Diesel and chemical productsmore » by Amyris. The CRADA scope also includes a techno-economic analysis of the overall production process of Amyris products from high-impact biomass feedstocks.« less

Prevalence of antibodies against Parainfluenza virus type 3, Respiratory syncitial virus and bovine Herpesvirus type 1 in sheep from Northern Prefectures of Japan.

PubMed

Giangaspero, Massimo; Savini, Giovanni; Orusa, Riccardo; Osawa, Takeshi; Harasawa, Ryô

2013-01-01

Ovine sera collected in the Prefectures of Hokkaido, Aomori and Iwate in the Northern Japan were examined for the presence of antibodies against Respiratory syncytial virus (RSV), bovine Herpesvirus type 1 (infectious bovine rhinotracheitis: IBR) and Parainfluenza virus type 3 (PIV3) using serum neutralisation (SN) and enzyme-linked immunosorbent assay (ELISA) tests. Twenty-three animals (11.73%) out of the 196 tested were sero-positive to PIV3. Sixteen animals (8.69%) out of the 184 tested reacted to RSV. No animals were positive to IBR antigen. Sero-conversions to PIV3 were detected in Hokkaido and Iwate (14.92% and 8.82%, respectively). Antibodies against RSV were detected in Hokkaido (9.23%) and Aomori (14.28%). Although no diagnostic measures were in place, the infections did not appear to be related to any reduction in sheep productivity.

Infectious bovine rhinotracheitis: study on the experimentally induced disease and its prevention using an inactivated, adjuvanted vaccine.

PubMed

Soulebot, J P; Guillemin, F; Brun, A; Dubourget, P; Espinasse, J; Terre, J

1982-01-01

Experimentally induced IBR was studied in calves. Intranasal challenge enabled reproducible results to be obtained, both from qualitative (clinical aspect) and quantitative points of view (virus excretion, temperature); local and general immunity were also evaluated. This challenge method is useful when studying IBR vaccines. The disease was also experimentally induced by putting healthy animals into contact with diffusor calves. A single injection of inactivated vaccine in oily adjuvant already conferred good protection; it was 100% successful against the experimentally induced disease when administered two times at a 7 or 14 day interval. Immunity obtained was long-lasting and even persisted up to one year. Therefore, this vaccine is advised for vaccination in both contaminated and high risk areas. Results obtained for both safety and potency suggest that this killed vaccine should be used rather than live vaccines.

Influence of Molecular Oxygen on Ortho-Para Conversion of Water Molecules

NASA Astrophysics Data System (ADS)

Valiev, R. R.; Minaev, B. F.

2017-07-01

The mechanism of influence of molecular oxygen on the probability of ortho-para conversion of water molecules and its relation to water magnetization are considered within the framework of the concept of paramagnetic spin catalysis. Matrix elements of the hyperfine ortho-para interaction via the Fermi contact mechanism are calculated, as well as the Maliken spin densities on water protons in H2O and O2 collisional complexes. The mechanism of penetration of the electron spin density into the water molecule due to partial spin transfer from paramagnetic oxygen is considered. The probability of ortho-para conversion of the water molecules is estimated by the quantum chemistry methods. The results obtained show that effective ortho-para conversion of the water molecules is possible during the existence of water-oxygen dimers. An external magnetic field affects the ortho-para conversion rate given that the wave functions of nuclear spin sublevels of the water protons are mixed in the complex with oxygen.

33 CFR 154.106 - Incorporation by reference: Where can I get a copy of the publications incorporated by reference...

Code of Federal Regulations, 2011 CFR

2011-07-01

...://www.iec.ch/: (1) IEC 309-1—Plugs, Socket-Outlets and Couplers for Industrial Purposes: Part 1, General Requirements, 1979, IBR approved for § 154.812. (2) IEC 309-2—Plugs, Socket-Outlets and Couplers for Industrial...

33 CFR 154.106 - Incorporation by reference: Where can I get a copy of the publications incorporated by reference...

Code of Federal Regulations, 2012 CFR

2012-07-01

...://www.iec.ch/: (1) IEC 309-1—Plugs, Socket-Outlets and Couplers for Industrial Purposes: Part 1, General Requirements, 1979, IBR approved for § 154.812. (2) IEC 309-2—Plugs, Socket-Outlets and Couplers for Industrial...

30 CFR 72.710 - Selection, fit, use, and maintenance of approved respirators.

Code of Federal Regulations, 2010 CFR

2010-07-01

.../code_of_federal_regulations/ibr_locations.html. This incorporation by reference was approved by the Director of the Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. [60 FR 30401, June 8...

40 CFR 272.2 - Incorporation by reference.

Code of Federal Regulations, 2010 CFR

2010-07-01

... reference by the Director of the Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51...-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html...

75 FR 7634 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-22

... public that the Postal Service has filed a request to add International Business Reply Service... entered into two additional International Business Reply Service (IBRS) Contracts.\\1\\ Additionally, the... to Establish Successor Instruments as Baseline International Business Reply Service Competitive...

40 CFR 65.13 - Incorporation by reference.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Zeeb Road, Ann Arbor, Michigan 48106. (1) ASTM D1946-77, Standard Method for Analysis of Reformed Gas by Gas Chromatography, IBR approved December 14, 2000 for §§ 65.64(e)(2) and 65.147(a)(4)(i) and (b...

40 CFR 65.13 - Incorporation by reference.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Zeeb Road, Ann Arbor, Michigan 48106. (1) ASTM D1946-77, Standard Method for Analysis of Reformed Gas by Gas Chromatography, IBR approved December 14, 2000 for §§ 65.64(e)(2) and 65.147(a)(4)(i) and (b...

77 FR 76091 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-26

... history. The Commission added International Business Reply Service Contract 1 to the competitive product... an expired International Business Reply Service (IBRS) competitive contract.\\1\\ The Postal Service... International Business Reply Service Competitive Contract 1 Negotiated Service Agreement, December 14, 2012...

16 CFR 1211.2 - Definition.

Code of Federal Regulations, 2010 CFR

2010-01-01

... incorporation by reference was approved by the Director of the Federal Register in accordance with 5 U.S.C. 552..._regulations/ibr_locations.html. [57 FR 60455, Dec. 21, 1992, as amended at 62 FR 46667, Sept. 4, 1997; 65 FR...

30 CFR 75.322 - Harmful quantities of noxious gases.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Federal Register in accordance with 5 U.S.C. 552(a) and 1 CFR part 51. Copies are available from the Mine..._federal_regulations/ibr_locations.html. [61 FR 26442, May 28, 1996, as amended at 67 FR 38386, June 4...

76 FR 11532 - New Postal Product

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-02

... POSTAL REGULATORY COMMISSION [Docket No. CP2011-61; Order No. 680] New Postal Product AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: This document addresses a recent Postal Service filing concerning an additional International Business Reply Service (IBRS) Competitive Contract 3. It...

10 CFR 431.15 - Materials incorporated by reference.

Code of Federal Regulations, 2012 CFR

2012-01-01

....03, IBR approved for § 431.12. (2) Institute of Electrical and Electronics Engineers, Inc., Standard... INDUSTRIAL EQUIPMENT Electric Motors Test Procedures, Materials Incorporated and Methods of Determining... provisions of National Electrical Manufacturers Association Standards Publication MG1-1993, Motors and...

40 CFR 600.011-93 - Reference materials.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Standard Test Method for Heat of Combustion of Liquid Hydrocarbon Fuels by Bomb Calorimeter 600.113-93, 600... Hydrocarbon Fuels by Bomb Calorimeter, IBR approved for §§ 600.113-93, 600.510-93, 600.113-08, and 600.510-08...

21 CFR 177.2400 - Perfluorocarbon cured elastomers.

Code of Federal Regulations, 2014 CFR

2014-04-01

... as are provided: Substances Limitations Carbon black (channel process of furnace combustion process... Park, MD 20740, or available for inspection at the National Archives and Records Administration (NARA....archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (2) Thermogravimetry...

77 FR 16568 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-21

...-filed Postal Service request to enter into an additional International Business Reply Service contract... additional International Business Reply Service (IBRS) contract.\\1\\ The Postal Service asserts that the... Service Filing of a Functionally Equivalent International Business Reply Service Competitive Contract 3...

77 FR 10577 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-22

...-filed Postal Service request to enter into an additional International Business Reply Service contract... additional International Business Reply Service (IBRS) contract.\\1\\ The Postal Service asserts that the... United States Postal Service Filing of a Functionally Equivalent International Business Reply Service...

46 CFR 160.115-5 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-10-01

... for §§ 160.115-7, 160.115-13, and 160.115-15. (4) MSC/Circular 980, Standardized Life-saving Appliance Evaluation and Test Report Forms, (February 13, 2001), IBR approved for § 160.115-13 (“IMO MSC Circ. 980...

The Ortho-to-para Ratio of Water Molecules Desorbed from Ice Made from Para-water Monomers at 11 K

NASA Astrophysics Data System (ADS)

Hama, Tetsuya; Kouchi, Akira; Watanabe, Naoki

2018-04-01

Water has two nuclear-spin isomers: ortho- and para-H2O. Some observations of interstellar space and cometary comae have reported the existence of gaseous H2O molecules with anomalous ortho-to-para ratios (OPRs) less than the statistical value of three. This has been often used to estimate the formation temperature of ice on dust, which is inferred to be below 50 K. The relation between the nuclear-spin dynamics of H2O in ice at low temperatures and the OPR of gaseous H2O desorbed from the ice has yet to be explored in a laboratory. Consequently, the true meaning of the observed OPRs remains debated. We measure the OPR of H2O photodesorbed from ice made from para-H2O monomers at 11 K, which was prepared by the sublimation of Ne from a para-H2O/Ne matrix. The photodesorbed H2O molecules from the ice have the statistical OPR value of three, demonstrating the immediate nuclear-spin-state mixing of H2O toward the statistical value of ice even at 11 K. The OPR of H2O thermally desorbed from the ice also shows the expected statistical value. Our results indicate that the OPR of H2O desorbed from interstellar ice should be the statistical value regardless of the formation process of the ice, which cannot be used to deduce the ice-formation temperature. This study highlights the importance of interstellar gas-phase processes in understanding anomalous abundance ratios of nuclear-spin isomers of molecules in space.

A Multivariate Model for Prediction of Obstructive Coronary Disease in Patients with Acute Chest Pain: Development and Validation.

PubMed

Correia, Luis Cláudio Lemos; Cerqueira, Maurício; Carvalhal, Manuela; Ferreira, Felipe; Garcia, Guilherme; Silva, André Barcelos da; Sá, Nicole de; Lopes, Fernanda; Barcelos, Ana Clara; Noya-Rabelo, Márcia

2017-04-01

Currently, there is no validated multivariate model to predict probability of obstructive coronary disease in patients with acute chest pain. To develop and validate a multivariate model to predict coronary artery disease (CAD) based on variables assessed at admission to the coronary care unit (CCU) due to acute chest pain. A total of 470 patients were studied, 370 utilized as the derivation sample and the subsequent 100 patients as the validation sample. As the reference standard, angiography was required to rule in CAD (stenosis ≥ 70%), while either angiography or a negative noninvasive test could be used to rule it out. As predictors, 13 baseline variables related to medical history, 14 characteristics of chest discomfort, and eight variables from physical examination or laboratory tests were tested. The prevalence of CAD was 48%. By logistic regression, six variables remained independent predictors of CAD: age, male gender, relief with nitrate, signs of heart failure, positive electrocardiogram, and troponin. The area under the curve (AUC) of this final model was 0.80 (95% confidence interval [95%CI] = 0.75 - 0.84) in the derivation sample and 0.86 (95%CI = 0.79 - 0.93) in the validation sample. Hosmer-Lemeshow's test indicated good calibration in both samples (p = 0.98 and p = 0.23, respectively). Compared with a basic model containing electrocardiogram and troponin, the full model provided an AUC increment of 0.07 in both derivation (p = 0.0002) and validation (p = 0.039) samples. Integrated discrimination improvement was 0.09 in both derivation (p < 0.001) and validation (p < 0.0015) samples. A multivariate model was derived and validated as an accurate tool for estimating the pretest probability of CAD in patients with acute chest pain. Atualmente, não existe um modelo multivariado validado para predizer a probabilidade de doença coronariana obstrutiva em pacientes com dor torácica aguda. Desenvolver e validar um modelo multivariado para predizer doen

Detection of the MW Transition Between Ortho and Para States

NASA Astrophysics Data System (ADS)

Kanamori, Hideto; Dehghani, Zeinab Tafti; Mizoguchi, Asao; Endo, Yasuki

2017-06-01

Thorough the detailed analysis of the hyperfine resolved rotational transitions, we have been pointed out that there exists not a little interaction between ortho and para states in the molecular Hamiltonian of S_2Cl_2. Using the ortho-para mixed molecular wavefunctions derived from the Hamiltonian, we calculated the transition moment and frequency of the ortho-para forbidden transitions in the cm- and mm-wave region, and picked up some promising candidate transitions for the spectroscopic detection. In the experiment, the S_2Cl_2 vapor with Ar buffer gas in a supersonic jet condition was used with FTMW spectrometer at National Chiao Tung University. As a result, seven hyperfine resolved rotational transitions in the cm-wave region were detected as the ortho-para transition at the predicted frequency within the experimental error range. The observed intensity was 10^{-3} smaller than that of an allowed transition, which is also consistent with the prediction. This is the first time the electric dipole transition between ortho and para states has been detected in a free isolated molecule. A. Mizoguchi, S. Ota, H. Kanamori, Y. Sumiyoshi, and Y. Endo, J. Mol. Spectrosc, 250, 86 (2008) Z. T. Dehghani, S. Ota, A. Mizoguchi and H. Kanamori, J. Phys. Chem. A, 117(39), 10041, (2013)

PREVENCIÓN DEL VIH/SIDA EN LOS CIRCUITOS DE LEVANTE HSH: UNA ASIGNATURA PENDIENTE1

PubMed Central

Barreda, Victoria; Carballo-Dieguez, Alex; Marone, Rubén; Balán, Iván; Pando, María Ángeles; Ávila, María Mercedes

2011-01-01

Resumen A partir de un relevamiento de tipo etnográfico, se describen lugares de encuentro de HSH en la Ciudad de Buenos Aires y sus prácticas sexuales. El reconocimiento de tales espacios, así como las características que asumen en ellos los encuentros sexuales entre los HSH, plantean obstáculos específicos en la adopción de comportamientos preventivos y, asimismo, generan nuevos desafíos para las actividades de prevención. Se plantean las dificultades y debates conceptuales que la misma categoría presenta, y sus consecuencias en el abordaje preventivo y teórico-metodológico para las ciencias sociales. Además, se proponen nuevos interrogantes acerca de los alcances y las limitaciones del modelo preventivo del VIH/Sida para HSH. PMID:21874154

Variação temporal do gradiente radial de o/h a partir de uma amostra de nebulosas planetárias

NASA Astrophysics Data System (ADS)

Maciel, W. J.; Costa, R. D. D.; Uchida, M. M. M.

2003-08-01

Gradientes radiais de abundância são observados no disco de nossa Galáxia e também em outras galáxias espirais. No caso da Galáxia, o principal problema relativo aos gradientes é sua variação temporal, que constitui um dos principais vínculos aos modelos de evolução química da Galáxia. As nebulosas planetárias são particularmente interessantes no estudo dos gradientes e suas variações, tanto espaciais como temporais. São objetos brilhantes, podendo ser observadas a grandes distâncias, e têm abundâncias relativamente precisas de diversos elementos químicos. Além disso, sendo originadas de estrelas com massas entre 0.8 e 8 massas solares na sequência principal, incluem objetos com idades e populações diferentes, o que as torna especialmente interessantes ao estudo da variação temporal dos gradientes. Neste trabalho, apresentamos resultados recentes sobre a variação temporal do gradiente de O/H a partir de uma amostra contendo cerca de 200 nebulosas, para as quais obtivemos distâncias por métodos estatísticos. As abundâncias foram parcialmente obtidas a partir de observações em Itajubá e La Silla, sendo as restantes obtidas da literatura. Os resultados mostram, pela primeira vez, evidências de um achatamento do gradiente de O/H, de -0.11 dex/kpc para -0.06 dex/kpc nos últimos 9 giga-anos ou de -0.08 dex/kpc para -0.06 dex/kpc nos últimos 5 giga-anos. Esses valores apresentam um bom acordo com alguns modelos recentes para a evolução química da Galáxia. (FAPESP/CNPq)

A Comparative Usage-Based Approach to the Reduction of the Spanish and Portuguese Preposition "Para"

ERIC Educational Resources Information Center

Gradoville, Michael Stephen

2013-01-01

This study examines the frequency effect of two-word collocations involving "para" "to," "for" (e.g. "fui para," "para que") on the reduction of "para" to "pa" (in Spanish) and "pra" (in Portuguese). Collocation frequency effects demonstrate that language speakers…

Preparation of ortho-para ratio controlled D2 gas for muon-catalyzed fusion.

PubMed

Imao, H; Ishida, K; Kawamura, N; Matsuzaki, T; Matsuda, Y; Toyoda, A; Strasser, P; Iwasaki, M; Nagamine, K

2008-05-01

A negative muon in hydrogen targets, e.g., D2 or D-T mixture, can catalyze nuclear fusions following a series of atomic processes involving muonic hydrogen molecular formation (muon-catalyzed fusion, muCF). The ortho-para state of D2 is a crucial parameter not only for enhancing the fusion rate but also to precisely investigate various muonic atom processes. We have developed a system for controlling and measuring the ortho-para ratio of D2 gas for muCF experiments. We successfully collected para-enriched D2 without using liquid-hydrogen coolant. Ortho-enriched D2 was also obtained by using a catalytic conversion method with a mixture of chromium oxide and alumina. The ortho-para ratio of D2 gas was measured with a compact Raman spectroscopy system. We produced large volume (5-30 l at STP), high-purity (less than ppm high-Z contaminant) D2 targets with a wide range of ortho-para ratios (ortho 20%-99%). By using the ortho-para controlled D2 in muCF experiments, we observed the dependence of muCF phenomena on the ortho-para ratio.

Rotational excitation of HCN by para- and ortho-H₂.

PubMed

Vera, Mario Hernández; Kalugina, Yulia; Denis-Alpizar, Otoniel; Stoecklin, Thierry; Lique, François

2014-06-14

Rotational excitation of the hydrogen cyanide (HCN) molecule by collisions with para-H2(j = 0, 2) and ortho-H2(j = 1) is investigated at low temperatures using a quantum time independent approach. Both molecules are treated as rigid rotors. The scattering calculations are based on a highly correlated ab initio 4-dimensional (4D) potential energy surface recently published. Rotationally inelastic cross sections among the 13 first rotational levels of HCN were obtained using a pure quantum close coupling approach for total energies up to 1200 cm(-1). The corresponding thermal rate coefficients were computed for temperatures ranging from 5 to 100 K. The HCN rate coefficients are strongly dependent on the rotational level of the H2 molecule. In particular, the rate coefficients for collisions with para-H2(j = 0) are significantly lower than those for collisions with ortho-H2(j = 1) and para-H2(j = 2). Propensity rules in favor of even Δj transitions were found for HCN in collisions with para-H2(j = 0) whereas propensity rules in favor of odd Δj transitions were found for HCN in collisions with H2(j ⩾ 1). The new rate coefficients were compared with previously published HCN-para-H2(j = 0) rate coefficients. Significant differences were found due the inclusion of the H2 rotational structure in the scattering calculations. These new rate coefficients will be crucial to improve the estimation of the HCN abundance in the interstellar medium.

Early Cretaceous wedge extrusion in the Indo-Burma Range accretionary complex: implications for the Mesozoic subduction of Neotethys in SE Asia

NASA Astrophysics Data System (ADS)

Zhang, Ji'en; Xiao, Wenjiao; Windley, Brian F.; Cai, Fulong; Sein, Kyaing; Naing, Soe

2017-06-01

The Indo-Burma Range (IBR) of Myanmar, the eastern extension of the Yarlung-Tsangpo Neotethyan belt of Tibet in China, contains mélanges with serpentinite, greenschist facies basalt, chert, sericite schist, silty slate and unmetamorphosed Triassic sandstone, mudstone and siltstone interbedded with chert in the east, and farther north high-pressure blueschist and eclogite blocks in the Naga Hills mélange. Our detailed mapping of the Mindat and Magwe sections in the middle IBR revealed a major 18 km antiformal isocline in a mélange in which greenschist facies rocks in the core decrease in grade eastwards and westwards symmetrically `outwards' to lower grade sericite schist and silty slate, and at the margins to unmetamorphosed sediments, and these metamorphic rocks are structurally repeated in small-scale imbricated thrust stacks. In the Mindat section the lower western boundary of the isoclinal mélange is a thrust on which the metamorphic rocks have been transported over unmetamorphosed sediments of the Triassic Pane Chaung Group, and the upper eastern boundary is a normal fault. These relations demonstrate that the IBR metamorphic rocks were exhumed by wedge extrusion in a subduction-generated accretionary complex. Along strike to the north in the Naga Hills is a comparable isoclinal mélange in which central eclogite lenses are succeeded `outwards' by layers of glaucophane schist and glaucophanite, and to lower grade greenschist facies sericite schist and slate towards the margins. In the Natchaung area (from west to east) unmetamorphosed Triassic sediments overlie quartzites, sericite schists, actinolite schists and meta-volcanic amphibolites derived from MORB-type basalt, which are in fault contact with peridotite. Olivine in the peridotite has undulatory extinction suggesting deformation at 600-700 °C, similar to the peak temperature of the amphibolite; these relations suggest generation in a metamorphic sole. The amphibolites have U/Pb zircon ages of 119

A Partially Saturated Constitutive Theory for Compacted Fills

DTIC Science & Technology

2004-06-01

degree of Doctor of Philosophy. COL James R. Rowan, EN , was Commander and Executive Director of ERDC, and Dr. James R. Houston was Director. CHAPTER...Reconsolidation Index CR Slope of the reconsolidation line Maximum Friction Angle of3 Friction Angle PHILIM traMaterial Ratio of minimum to maximum4 Phi Ratio PH ...Josa, A., (1988). "Un modelo elastoplastico para suelos no saturados," Tesis Doctorae, Universitat Politecnica de Catalunya, Barcelons, Spain. Lawton

45 CFR 170.299 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-10-01

.../o Medical Informatics The Regenstrief Institute, Inc 410 West 10th Street, Suite 2000 Indianapolis... (301) 594-5983 or http://www.nlm.nih.gov/. (1) International Health Terminology Standards Development... 2009, IBR approved for § 170.207. (2) International Health Terminology Standards Development...

9 CFR 201.71 - Scales; accurate weights, repairs, adjustments or replacements after inspection.

Code of Federal Regulations, 2010 CFR

2010-01-01

... contractors, market agencies, dealers, packers, and live poultry dealers to weigh livestock, livestock.... All approved material is available for inspection at the National Archives and Records Administration... http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. Also, it is...

77 FR 12888 - International Mail Contract

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-02

... instant contract is functionally equivalent to the IBRS 3 baseline contract originally filed in Docket Nos... product, also authorized functionally equivalent agreements to be included within the product, provided... Service Filing of a Functionally Equivalent International Business Reply Service Competitive Contract 3...

78 FR 21171 - International Mail Product

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-09

... POSTAL REGULATORY COMMISSION [Docket No. CP2013-57; Order No. 1690] International Mail Product... have the Agreement included within the existing IBRS Competitive Contract 3 product on grounds of... Contract 3 product in Docket No. CP2012-18. Id. at 3. [[Page 21172

Usos de Mets Para La Planificación, Monitoreo e Interpretación en Pastizales Áridos

USDA-ARS?s Scientific Manuscript database

Los modelos de estado y transición (METs) representan los posibles cambios en el estado ecológico de una clase específica de tierra (un sitio ecológico). Los METs permiten tener una comprensión general de los cambios en el estado ecológico y cómo gestionarlos. Pero los METs también se pueden usar di...

77 FR 66087 - Federal Perkins Loan Program, Federal Family Education Loan Program, and William D. Ford Federal...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-01

...The Secretary amends the Federal Perkins Loan (Perkins Loan) program, Federal Family Education Loan (FFEL) program, and William D. Ford Federal Direct Loan (Direct Loan) program regulations. These final regulations implement a new Income-Contingent Repayment (ICR) plan in the Direct Loan program based on the President's ``Pay As You Earn'' repayment initiative, incorporate recent statutory changes to the Income-Based Repayment (IBR) plan in the Direct Loan and FFEL programs, and streamline and add clarity to the total and permanent disability (TPD) discharge process for borrowers in loan programs under title IV of the Higher Education Act of 1965, as amended (HEA). These final regulations implementing a new ICR plan and the statutory changes to the IBR plan will assist borrowers in repaying their loans while the changes to the TPD discharge process will reduce burden for borrowers who are disabled and seeking a discharge of their title IV debt.

Analyzing and Visualizing Cosmological Simulations with ParaView

NASA Astrophysics Data System (ADS)

Woodring, Jonathan; Heitmann, Katrin; Ahrens, James; Fasel, Patricia; Hsu, Chung-Hsing; Habib, Salman; Pope, Adrian

2011-07-01

The advent of large cosmological sky surveys—ushering in the era of precision cosmology—has been accompanied by ever larger cosmological simulations. The analysis of these simulations, which currently encompass tens of billions of particles and up to a trillion particles in the near future, is often as daunting as carrying out the simulations in the first place. Therefore, the development of very efficient analysis tools combining qualitative and quantitative capabilities is a matter of some urgency. In this paper, we introduce new analysis features implemented within ParaView, a fully parallel, open-source visualization toolkit, to analyze large N-body simulations. A major aspect of ParaView is that it can live and operate on the same machines and utilize the same parallel power as the simulation codes themselves. In addition, data movement is in a serious bottleneck now and will become even more of an issue in the future; an interactive visualization and analysis tool that can handle data in situ is fast becoming essential. The new features in ParaView include particle readers and a very efficient halo finder that identifies friends-of-friends halos and determines common halo properties, including spherical overdensity properties. In combination with many other functionalities already existing within ParaView, such as histogram routines or interfaces to programming languages like Python, this enhanced version enables fast, interactive, and convenient analyses of large cosmological simulations. In addition, development paths are available for future extensions.

Toxic releases and risk disparity: a spatiotemporal model of industrial ecology and social empowerment.

PubMed

Aoyagi, Hannah; Ogunseitan, Oladele A

2015-06-02

Information-based regulations (IBRs) are founded on the theoretical premise that public participation in accomplishing policy goals is empowered by open access to information. Since its inception in 1988, the Toxics Release Inventory (TRI) has provided the framework and regulatory impetus for the compilation and distribution of data on toxic releases associated with industrial development, following the tenets of IBR. As TRI emissions are reputed to disproportionately affect low-income communities, we investigated how demographic characteristics are related to change in TRI emissions and toxicity risks between 1989 and 2002, and we sought to identify factors that predict these changes. We used local indicators of spatial association (LISA) maps and spatial regression techniques to study risk disparity in the Los Angeles urban area. We also surveyed 203 individuals in eight communities in the same region to measure the levels of awareness of TRI, attitudes towards air pollution, and general environmental risk. We discovered, through spatial lag models, that changes in gross and toxic emissions are related to community ethnic composition, poverty level, home ownership, and base 1989 emissions (R-square=0.034-0.083). We generated a structural equation model to explain the determinants of social empowerment to act on the basis of environmental information. Hierarchical confirmatory factor analysis (HCFA) supports the theoretical model that individual empowerment is predicted by risk perception, worry, and awareness (Chi-square=63.315, p=0.022, df=42). This study provides strong evidence that spatiotemporal changes in regional-scale environmental risks are influenced by individual-scale empowerment mediated by IBRs.

Toxic Releases and Risk Disparity: A Spatiotemporal Model of Industrial Ecology and Social Empowerment

PubMed Central

Aoyagi, Hannah; Ogunseitan, Oladele A.

2015-01-01

Information-based regulations (IBRs) are founded on the theoretical premise that public participation in accomplishing policy goals is empowered by open access to information. Since its inception in 1988, the Toxics Release Inventory (TRI) has provided the framework and regulatory impetus for the compilation and distribution of data on toxic releases associated with industrial development, following the tenets of IBR. As TRI emissions are reputed to disproportionately affect low-income communities, we investigated how demographic characteristics are related to change in TRI emissions and toxicity risks between 1989 and 2002, and we sought to identify factors that predict these changes. We used local indicators of spatial association (LISA) maps and spatial regression techniques to study risk disparity in the Los Angeles urban area. We also surveyed 203 individuals in eight communities in the same region to measure the levels of awareness of TRI, attitudes towards air pollution, and general environmental risk. We discovered, through spatial lag models, that changes in gross and toxic emissions are related to community ethnic composition, poverty level, home ownership, and base 1989 emissions (R-square = 0.034–0.083). We generated a structural equation model to explain the determinants of social empowerment to act on the basis of environmental information. Hierarchical confirmatory factor analysis (HCFA) supports the theoretical model that individual empowerment is predicted by risk perception, worry, and awareness (Chi-square = 63.315, p = 0.022, df = 42). This study provides strong evidence that spatiotemporal changes in regional-scale environmental risks are influenced by individual-scale empowerment mediated by IBRs. PMID:26042368

Indo-Burma Range: a belt of accreted microcontinents, ophiolites and Mesozoic-Paleogene flyschoid sediments

NASA Astrophysics Data System (ADS)

Acharyya, S. K.

2015-07-01

This study provides an insight into the lithotectonic evolution of the N-S trending Indo-Burma Range (IBR), constituting the southern flank of the Himalayan syntaxis. Paleogene flyschoid sediments (Disang-Barail) that represent a shallow marine to deltaic environment mainly comprise the west-central sector of IBR, possibly resting upon a continental base. On the east, these sequences are tectonically flanked by the Eocene olistostromal facies of the Disang, which developed through accretion of trench sediments during the subduction. The shelf and trench facies sequences of the Disang underwent overthrusting from the east, giving rise to two ophiolite suites ( Naga Hills Lower Ophiolite ( NHLO) and Victoria Hills Upper Ophiolite ( VHUO), but with different accretion history. The ophiolite and ophiolite cover rock package were subsequently overthrusted by the Proterozoic metamorphic sequence, originated from the Burmese continent. The NHLO suite of Late Jurassic to Early Eocene age is unconformably overlain by mid-Eocene shallow marine ophiolite-derived clastics. On the south, the VHUO of Mesozoic age is structurally underlain by continental metamorphic rocks. The entire package in Victoria Hills is unconformably overlain by shallow marine Late Albian sediments. Both the ophiolite suites and the sandwiched continental metamorphic rocks are thrust westward over the Paleogene shelf sediments. These dismembered ophiolites and continental metamorphic rocks suggest thin-skinned tectonic detachment processes in IBR, as reflected from the presence of klippe of continental metamorphic rocks over the NHLO and the flyschoid Disang floor sediments and half windows exposing the Disang beneath the NHLO.

Explicación de las disparidades raciales en la salud neonatal en Brasil*

PubMed Central

Nyarko, Kwame A.; López-Camelo, Jorge; Castilla, Eduardo E.; Wehby, George L.

2015-01-01

Objetivos. Buscamos cuantificar la manera en que los efectos socioeconómicos, demográficos, geográficos y de atención de salud explican las disparidades raciales en las tasas de bajo peso al nacer y prematuridad en Brasil. Métodos. Utilizamos una muestra de 8 949 niños nacidos entre 1995 y el 2009 en 15 ciudades y 7 provincias de Brasil. Nos centramos en las disparidades en la prevalencia de bajo peso al nacer (< 2 500 g) y prematuridad (< 37 semanas de gestación) en recién nacidos de ascendencia solo africana o mezclada con otras ascendencias y de ascendencia solo europea. Usamos un modelo de descomposición para cuantificar la contribución de los factores conceptualmente pertinentes a esas disparidades. Resultados. El modelo permitió explicar entre 45% y 94% de las disparidades en cuanto al bajo peso al nacer y entre 64% y 94% de las disparidades en cuanto a la prematuridad entre los grupos de ascendencia africana y de ascendencia europea. Las diferencias en el uso de atención prenatal y en la ubicación geográfica fueron los factores más importantes, seguidos por las diferencias socioeconómicas. El modelo permitió explicar la mayoría de las disparidades en los recién nacidos de ascendencia africana mezclada y parte de las disparidades en los de ascendencia solo africana. Conclusiones. En las políticas públicas para mejorar la salud infantil se deben abordar las diferencias en cuanto a la atención prenatal y la ubicación geográfica a fin de reducir las disparidades en materia de salud entre los recién nacidos de ascendencia africana y los de ascendencia europea en Brasil.

Analysis of groundwater discharge with a lumped-parameter model, using a case study from Tajikistan

NASA Astrophysics Data System (ADS)

Pozdniakov, S. P.; Shestakov, V. M.

A lumped-parameter model of groundwater balance is proposed that permits an estimate of discharge variability in comparison with the variability of recharge, by taking into account the influence of aquifer parameters. Recharge-discharge relationships are analysed with the model for cases of deterministic and stochastic recharge time-series variations. The model is applied to study the temporal variability of groundwater discharge in a river valley in the territory of Tajikistan, an independent republic in Central Asia. Résumé Un modèle global de bilan d'eau souterraine a été développé pour estimer la variabilité de l'écoulement par rapport à celle de la recharge, en prenant en compte l'influence des paramètres de l'aquifère. Les relations entre recharge et écoulement sont analysées à l'aide du modèle pour des variations des chroniques de recharge soit déterministes, soit stochastiques. Le modèle est appliquéà l'étude de la variabilité temporelle de l'écoulement souterrain vers une rivière, dans le Tadjikistan, une république indépendante d'Asie centrale. Resumen Se propone un modelo de parámetros concentrados para realizar el balance de aguas subterráneas, el cual permite estimar la variabilidad en la descarga con respecto a la variabilidad en la recarga, en función de los parámetros que caracterizan el acuífero. Las relaciones entre recarga y descarga se analizan con el modelo para distintos casos de series temporales de recarga, tanto deterministas como estocásticas. El modelo se aplica al estudio de la variabilidad temporal de la descarga en un valle aluvial de Tadyikistán, una república independiente del Asia Central.

77 FR 65372 - Agency Information Collection Activities; Submission to the Office of Management and Budget for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-26

...; Submission to the Office of Management and Budget for Review and Approval; Comment Request: Federal Family... of Collection: Federal Family Education Loan (FFEL) Program Income Based Repayment (IBR) Plan Request... Loan) and Federal Family Education Loan (FFEL) Programs may request an Income-Based or Income...

46 CFR 160.076-11 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-10-01

... the public. All approved material is available for inspection at the National Archives and Records Administration (NARA) and at Coast Guard Headquarters. Contact Commandant (CG-ENG-4), Attn: Lifesaving and Fire.../federal_register/code_of_federal_regulations/ibr_locations.html. (b) Underwriters Laboratories (UL...

46 CFR 160.076-11 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-10-01

... the public. All approved material is available for inspection at the National Archives and Records Administration (NARA) and at Coast Guard Headquarters. Contact Commandant (CG-ENG-4), Attn: Lifesaving and Fire.../federal_register/code_of_federal_regulations/ibr_locations.html. (b) Underwriters Laboratories (UL...

40 CFR 141.852 - Analytical methods and laboratory certification.

Code of Federal Regulations, 2014 CFR

2014-07-01

.... All approved material is available for inspection either electronically at www.regulations.gov, in....gov/federal_register/code_of_federal_regulations/ibr_ locations.html. (1) American Public Health..., “Enzyme Substrate Test”, Colilert® and Colisure®. (2) Charm Sciences, Inc., 659 Andover Street, Lawrence...

40 CFR 141.852 - Analytical methods and laboratory certification.

Code of Federal Regulations, 2013 CFR

2013-07-01

.... All approved material is available for inspection either electronically at www.regulations.gov, in....gov/federal_register/code_of_federal_regulations/ibr_ locations.html. (1) American Public Health..., “Enzyme Substrate Test”, Colilert® and Colisure®. (2) Charm Sciences, Inc., 659 Andover Street, Lawrence...

49 CFR 173.137 - Class 8-Assignment of packing group.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Resistance Test (TER)” (IBR, see § 171.7 of this subchapter) or Number 431, “In Vitro Skin Corrosion: Human... aluminum surfaces exceeding 6.25 mm (0.25 inch) a year at a test temperature of 55 °C (130 °F) when tested...

49 CFR 173.137 - Class 8-Assignment of packing group.

Code of Federal Regulations, 2013 CFR

2013-10-01

... Resistance Test (TER)” (IBR, see § 171.7 of this subchapter) or Number 431, “In Vitro Skin Corrosion: Human... aluminum surfaces exceeding 6.25 mm (0.25 inch) a year at a test temperature of 55 °C (130 °F) when tested...

40 CFR 49.123 - General provisions.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., road construction and road maintenance, fertilization, logging operations, and forest management... oil. Fugitive dust means a particulate matter emission made airborne by forces of wind, mechanical... § 49.123(a). (vii) ASTM D2880-03, Standard Specification for Gas Turbine Fuel Oils, IBR approved for...

40 CFR 49.123 - General provisions.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., road construction and road maintenance, fertilization, logging operations, and forest management... oil. Fugitive dust means a particulate matter emission made airborne by forces of wind, mechanical... § 49.123(a). (vii) ASTM D2880-03, Standard Specification for Gas Turbine Fuel Oils, IBR approved for...

40 CFR 49.123 - General provisions.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., road construction and road maintenance, fertilization, logging operations, and forest management... oil. Fugitive dust means a particulate matter emission made airborne by forces of wind, mechanical... § 49.123(a). (vii) ASTM D2880-03, Standard Specification for Gas Turbine Fuel Oils, IBR approved for...

40 CFR 49.123 - General provisions.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., road construction and road maintenance, fertilization, logging operations, and forest management... oil. Fugitive dust means a particulate matter emission made airborne by forces of wind, mechanical... § 49.123(a). (vii) ASTM D2880-03, Standard Specification for Gas Turbine Fuel Oils, IBR approved for...

30 CFR 700.5 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

.../federal_register/code_of_federal_regulations/ibr_locations.html. Incorporation by reference provisions... pursuant to section 523 of the Act to regulate surface coal mining and reclamation operations on Federal... no approved State or Federal program and coal exploration and surface coal mining and reclamation...

7 CFR 51.767 - Mature.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Florida Citrus Industry, Part 1, Chapter 20-13 Market Classification, Maturity Standards and Processing or... 2065-S, 14th and Independence Ave., Washington, DC 20250 or at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. ...

7 CFR 51.1158 - Mature.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Citrus Industry, Part 1, Chapter 20-13 Market Classification, Maturity Standards and Processing or... 2065-S, 14th and Independence Ave., Washington, DC 20250 or at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. ...

40 CFR 52.2820 - Identification of plan.

Code of Federal Regulations, 2010 CFR

2010-07-01

... national ambient air quality standards. (b) Incorporation by reference. (1) Material listed in paragraphs..., DC; or the National Archives and Records Administration (NARA). For information on the availability.../code_of_federal_regulations/ibr_locations.html. (c) EPA approved regulations. Table 52.2820—EPA...

40 CFR 52.2820 - Identification of plan.

Code of Federal Regulations, 2013 CFR

2013-07-01

... national ambient air quality standards. (b) Incorporation by reference. (1) Material listed in paragraphs..., DC; or the National Archives and Records Administration (NARA). For information on the availability.../code_of_federal_regulations/ibr_locations.html. (c) EPA approved regulations. Table 52.2820—EPA...

40 CFR 52.2820 - Identification of plan.

Code of Federal Regulations, 2012 CFR

2012-07-01

... national ambient air quality standards. (b) Incorporation by reference. (1) Material listed in paragraphs..., DC; or the National Archives and Records Administration (NARA). For information on the availability.../code_of_federal_regulations/ibr_locations.html. (c) EPA approved regulations. Table 52.2820—EPA...

40 CFR 141.131 - Analytical requirements.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Disinfectant Residuals, Disinfection Byproducts, and... Constitution Avenue, NW., EPA West, Room B102, Washington, DC 20460, or at the National Archives and Records...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. EPA Method 552...

40 CFR 52.2820 - Identification of plan.

Code of Federal Regulations, 2011 CFR

2011-07-01

... national ambient air quality standards. (b) Incorporation by reference. (1) Material listed in paragraphs..., DC; or the National Archives and Records Administration (NARA). For information on the availability.../code_of_federal_regulations/ibr_locations.html. (c) EPA approved regulations. Table 52.2820—EPA...

40 CFR 52.2820 - Identification of plan.

Code of Federal Regulations, 2014 CFR

2014-07-01

... national ambient air quality standards. (b) Incorporation by reference. (1) Material listed in paragraphs..., DC; or the National Archives and Records Administration (NARA). For information on the availability.../code_of_federal_regulations/ibr_locations.html. (c) EPA approved regulations. Table 52.2820—EPA...

21 CFR 177.1430 - Isobutylene-butene copolymers.

Code of Federal Regulations, 2013 CFR

2013-04-01

...) of this section. (b) Specifications: Isobutylene-butene copolymers Molecular weight (range) Viscosity...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (2) Viscosity. Viscosity shall be determined by ASTM method D445-74, “Test for Kinematic Viscosity of Transparent and...

21 CFR 177.1430 - Isobutylene-butene copolymers.

Code of Federal Regulations, 2012 CFR

2012-04-01

...) of this section. (b) Specifications: Isobutylene-butene copolymers Molecular weight (range) Viscosity...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (2) Viscosity. Viscosity shall be determined by ASTM method D445-74, “Test for Kinematic Viscosity of Transparent and...

21 CFR 177.1430 - Isobutylene-butene copolymers.

Code of Federal Regulations, 2011 CFR

2011-04-01

...) of this section. (b) Specifications: Isobutylene-butene copolymers Molecular weight (range) Viscosity...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (2) Viscosity. Viscosity shall be determined by ASTM method D445-74, “Test for Kinematic Viscosity of Transparent and...

7 CFR 801.7 - Reference methods and tolerances for near-infrared spectroscopy (NIRS) analyzers.

Code of Federal Regulations, 2013 CFR

2013-01-01

..._of_federal_regulations/ibr_locations.html. (b) Tolerances—(1) NIRS wheat protein analyzers. The... Method 992.23. (3) NIRS corn oil, protein, and starch analyzers. The maintenance tolerances for the NIRS... methods and tolerances for near-infrared spectroscopy (NIRS) analyzers. (a) Reference methods. (1) The...

7 CFR 801.7 - Reference methods and tolerances for near-infrared spectroscopy (NIRS) analyzers.

Code of Federal Regulations, 2011 CFR

2011-01-01

..._of_federal_regulations/ibr_locations.html. (b) Tolerances—(1) NIRS wheat protein analyzers. The... Method 992.23. (3) NIRS corn oil, protein, and starch analyzers. The maintenance tolerances for the NIRS... methods and tolerances for near-infrared spectroscopy (NIRS) analyzers. (a) Reference methods. (1) The...

7 CFR 801.7 - Reference methods and tolerances for near-infrared spectroscopy (NIRS) analyzers.

Code of Federal Regulations, 2014 CFR

2014-01-01

..._of_federal_regulations/ibr_locations.html. (b) Tolerances—(1) NIRS wheat protein analyzers. The... Method 992.23. (3) NIRS corn oil, protein, and starch analyzers. The maintenance tolerances for the NIRS... methods and tolerances for near-infrared spectroscopy (NIRS) analyzers. (a) Reference methods. (1) The...

7 CFR 801.7 - Reference methods and tolerances for near-infrared spectroscopy (NIRS) analyzers.

Code of Federal Regulations, 2012 CFR

2012-01-01

..._of_federal_regulations/ibr_locations.html. (b) Tolerances—(1) NIRS wheat protein analyzers. The... Method 992.23. (3) NIRS corn oil, protein, and starch analyzers. The maintenance tolerances for the NIRS... methods and tolerances for near-infrared spectroscopy (NIRS) analyzers. (a) Reference methods. (1) The...

46 CFR 110.10-1 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-10-01

... Classing Mobile Offshore Drilling Units, Part 4 Machinery and Systems, 2001 (“ABS MODU Rules”), IBR... Hazardous (Classified) Locations: Type of Protection—Encapsulation “m”, approved July 31, 2009 (“ANSI/ISA... Practice for Classification of Locations for Electrical Installations at Petroleum Facilities Classified as...

Determination of inadvertent atrial capture during para-Hisian pacing.

PubMed

Obeyesekere, Manoj; Leong-Sit, Peter; Skanes, Allan; Krahn, Andrew; Yee, Raymond; Gula, Lorne J; Bennett, Matthew; Klein, George J

2011-08-01

Inadvertent capture of the atrium will lead to spurious results during para-Hisian pacing. We sought to establish whether the stimulation-to-atrial electrogram interval at the proximal coronary sinus (stim-PCS) or high right atrium (stim-HRA) could signal inadvertent atrial capture. Para-Hisian pacing with and without intentional atrial capture was performed in 31 patients. Stim-HRA and stim-PCS intervals were measured with atrial capture, His plus para-Hisian ventricular (H+V) capture, and para-Hisian ventricular (V) capture alone. The mean stim-HRA interval was significantly shorter with atrial capture (66 ± 18 ms) than with H+V (121 ± 27 ms, P < 0.001) or V capture alone (174 ± 38 ms, P < 0.001). The mean stim-PCS interval was significantly shorter with atrial capture (51 ± 16 ms) than with H+V (92 ± 22 ms, P<0.001) or V capture alone (146 ± 33 ms, P < 0.001). A stim-PCS < 60 ms (stim-HRA < 70 ms) was observed only with atrial capture. A stim-PCS >90 ms (stim-HRA >100 ms) was observed only in the absence of atrial capture. A stim-HRA of < 85 ms was highly specific and stim-PCS of < 85 ms highly sensitive at identifying atrial capture. Stim-HRA intervals of 75 to 97 ms and stim-PCS intervals of 65 to 88 ms were observed with either atrial, His, or para-Hisian ventricular capture without atrial capture. In this overlap zone, all patients demonstrated a stim-PCS or stim-HRA interval prolongation of at least 20 ms when the catheter was advanced to avoid deliberate atrial pacing. The QRS morphology was of limited value in distinguishing atrial capture due to concurrent ventricular or H+V capture, as observed in 20 of 31 (65%) patients. Stim-PCS and stim-HRA intervals can be used to monitor for inadvertent atrial capture during para-Hisian pacing. A stim-PCS < 60 ms (or stim-HRA < 70 ms) and stim-PCS > 90 ms (or stim-HRA > 100 ms) were observed only with and without atrial capture, respectively, but there was significant overlap between these values. Deliberate

Norma para la Certificación de Aplicadores de Plaguicidas Revisada

EPA Pesticide Factsheets

La EPA emitió una propuesta para la revisión de la norma para la Certificación de Aplicadores de Plaguicidas. La norma ayudará a mantener nuestras comunidades seguras, salvaguardar el medio ambiente y reducir el riesgo a los que aplican los plaguicidas.

Conformational explosion: Understanding the complexity of short chain para-dialkylbenzene potential energy surfaces

NASA Astrophysics Data System (ADS)

Mishra, Piyush; Hewett, Daniel M.; Zwier, Timothy S.

2018-05-01

The single-conformation ultraviolet and infrared spectroscopy of three short-chain para-dialkylbenzenes (para-diethylbenzene, para-dipropylbenzene, and para-dibutylbenzene) is reported for the jet-cooled, isolated molecules. The present study builds off previous work on single-chain n-alkylbenzenes, where an anharmonic local mode Hamiltonian method was developed to account for stretch-bend Fermi resonance in the alkyl CH stretch region [D. P. Tabor et al., J. Chem. Phys. 144, 224310 (2016)]. The jet-cooled molecules are interrogated using laser-induced fluorescence (LIF) excitation, fluorescence dip infrared spectroscopy, and dispersed fluorescence. The LIF spectra in the S1 ← S0 origin region show a dramatic increase in the number of resolved transitions with increasing length of the alkyl chains, reflecting an explosion in the number of unique low-energy conformations formed when two independent alkyl chains are present. Since the barriers to isomerization of the alkyl chain are similar in size, this results in an "egg carton" shaped potential energy surface. A combination of electronic frequency shift and alkyl CH stretch infrared spectra is used to generate a consistent set of conformational assignments. Using these experimental techniques in conjunction with computational methods, subsets of origin transitions in the LIF excitation spectrum can be classified into different conformational families. Two conformations are resolved in para-diethylbenzene, seven in para-dipropylbenzene, and about nineteen in para-dibutylbenzene. These chains are largely independent of each other as there are no new single-chain conformations induced by the presence of a second chain. A cursory LIF excitation scan of para-dioctylbenzene shows a broad congested spectrum at frequencies consistent with interactions of alkyl chains with the phenyl π cloud.

Conformational explosion: Understanding the complexity of short chain para-dialkylbenzene potential energy surfaces.

PubMed

Mishra, Piyush; Hewett, Daniel M; Zwier, Timothy S

2018-05-14

The single-conformation ultraviolet and infrared spectroscopy of three short-chain para-dialkylbenzenes (para-diethylbenzene, para-dipropylbenzene, and para-dibutylbenzene) is reported for the jet-cooled, isolated molecules. The present study builds off previous work on single-chain n-alkylbenzenes, where an anharmonic local mode Hamiltonian method was developed to account for stretch-bend Fermi resonance in the alkyl CH stretch region [D. P. Tabor et al., J. Chem. Phys. 144, 224310 (2016)]. The jet-cooled molecules are interrogated using laser-induced fluorescence (LIF) excitation, fluorescence dip infrared spectroscopy, and dispersed fluorescence. The LIF spectra in the S 1 ← S 0 origin region show a dramatic increase in the number of resolved transitions with increasing length of the alkyl chains, reflecting an explosion in the number of unique low-energy conformations formed when two independent alkyl chains are present. Since the barriers to isomerization of the alkyl chain are similar in size, this results in an "egg carton" shaped potential energy surface. A combination of electronic frequency shift and alkyl CH stretch infrared spectra is used to generate a consistent set of conformational assignments. Using these experimental techniques in conjunction with computational methods, subsets of origin transitions in the LIF excitation spectrum can be classified into different conformational families. Two conformations are resolved in para-diethylbenzene, seven in para-dipropylbenzene, and about nineteen in para-dibutylbenzene. These chains are largely independent of each other as there are no new single-chain conformations induced by the presence of a second chain. A cursory LIF excitation scan of para-dioctylbenzene shows a broad congested spectrum at frequencies consistent with interactions of alkyl chains with the phenyl π cloud.

Kit para aplicar la metodología de Lean en el gobierno

EPA Pesticide Factsheets

Este Kit para comenzar a aplicar la metodología Lean (Gobierno optimizado) ofrece información para ayudar a las agencias de protección ambiental a planificar e implementar iniciativas Lean exitosas.

48 CFR 334.203-70 - HHS solicitation provisions and contract clauses.

Code of Federal Regulations, 2012 CFR

2012-10-01

... provisions and contract clauses. 334.203-70 Section 334.203-70 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management... Value Management System—Pre-Award IBR, in solicitations that will require the contractor to use an EVMS...

48 CFR 334.203-70 - HHS solicitation provisions and contract clauses.

Code of Federal Regulations, 2014 CFR

2014-10-01

... provisions and contract clauses. 334.203-70 Section 334.203-70 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management... Value Management System—Pre-Award IBR, in solicitations that will require the contractor to use an EVMS...

48 CFR 334.203-70 - HHS solicitation provisions and contract clauses.

Code of Federal Regulations, 2013 CFR

2013-10-01

... provisions and contract clauses. 334.203-70 Section 334.203-70 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management... Value Management System—Pre-Award IBR, in solicitations that will require the contractor to use an EVMS...

48 CFR 334.203-70 - HHS solicitation provisions and contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... provisions and contract clauses. 334.203-70 Section 334.203-70 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management... Value Management System—Pre-Award IBR, in solicitations that will require the contractor to use an EVMS...

47 CFR 22.901 - Cellular service requirements and limitations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... (“AMPS”) to cellular telephones designed in conformance with the specifications contained in sections 1.../federal_register/code_of_federal_regulations/ibr_locations.html. (2) Provide AMPS, upon request, to... that the quality of AMPS provided, in terms of geographic coverage and traffic capacity, is fully...

40 CFR 1042.910 - Reference materials.

Code of Federal Regulations, 2012 CFR

2012-07-01

... incorporated by reference into this part. The Director of the Federal Register approved the incorporation by... and Radiation Docket and Information Center, 1301 Constitution Ave., NW., Room B102, EPA West Building.../federal_register/code_of_federal_regulations/ibr_locations.html. (a) IMO material. This paragraph (a...

40 CFR 1043.100 - Reference materials.

Code of Federal Regulations, 2012 CFR

2012-07-01

... this part. The Director of the Federal Register approved the incorporation by reference as prescribed... Docket and Information Center, 1301 Constitution Ave., NW., Room B102, EPA West Building, Washington, DC.../federal_register/code_of_federal_regulations/ibr_locations.html. (a) IMO material. This paragraph (a...

40 CFR 1043.100 - Reference materials.

Code of Federal Regulations, 2011 CFR

2011-07-01

... this part. The Director of the Federal Register approved the incorporation by reference as prescribed... Docket and Information Center, 1301 Constitution Ave., NW., Room B102, EPA West Building, Washington, DC.../federal_register/code_of_federal_regulations/ibr_locations.html. (a) IMO material. This paragraph (a...

40 CFR 1042.910 - Reference materials.

Code of Federal Regulations, 2011 CFR

2011-07-01

... incorporated by reference into this part. The Director of the Federal Register approved the incorporation by... and Radiation Docket and Information Center, 1301 Constitution Ave., NW., Room B102, EPA West Building.../federal_register/code_of_federal_regulations/ibr_locations.html. (a) IMO material. This paragraph (a...

77 FR 13675 - Self-Regulatory Organizations; Chicago Stock Exchange, Inc.; Order Approving a Proposed Rule...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-07

... allow Institutional Brokers to carry out business strategies similar to those of other participants on... to engage in business activities beyond those handled by IBRs, such as over-the- counter (``OTC... registered with the Exchange as Institutional Broker could maintain other lines of business separate and...

46 CFR 54.01-1 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-10-01

...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. The material is also...) American Society of Mechanical Engineers (ASME) International, Three Park Avenue, New York, NY 10016-5990: (1) ASME Boiler and Pressure Vessel Code, Section VIII, Division 1, Rules for Construction of...

46 CFR 54.01-1 - Incorporation by reference.

Code of Federal Regulations, 2011 CFR

2011-10-01

...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. The material is also...) American Society of Mechanical Engineers (ASME) International, Three Park Avenue, New York, NY 10016-5990: (1) ASME Boiler and Pressure Vessel Code, Section VIII, Division 1, Rules for Construction of...

46 CFR 54.01-1 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-10-01

...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. The material is also... of Mechanical Engineers (ASME) International, Three Park Avenue, New York, NY 10016-5990: (1) ASME Boiler and Pressure Vessel Code, Section VIII, Division 1, Rules for Construction of Pressure Vessels...

46 CFR 54.01-1 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-10-01

...://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. The material is also... of Mechanical Engineers (ASME) International, Three Park Avenue, New York, NY 10016-5990: (1) ASME Boiler and Pressure Vessel Code, Section VIII, Division 1, Rules for Construction of Pressure Vessels...

16 CFR 309.10 - Alternative vehicle fuel rating.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Electricity) and of Manufacturers of Electric Vehicle Fuel Dispensing Systems § 309.10 Alternative vehicle.../code_of_federal_regulations/ibr_locations.html. (b) If you are a manufacturer of electric vehicle fuel... electric vehicle fuel dispensing system, you must possess a reasonable basis, consisting of competent and...

75 FR 2541 - Environmental Impact Statements and Regulations; Availability of EPA Comments

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-15

..., 158th Fighter Wing Vermont Air National Guard Project, Proposed Realignment of National Guard Avenue and... the preparing agency. EIS No. 20090401, ERP No. F-IBR-K39118-CA, Delta-Mendota Canal/ California... Delta-Mendota Water Authority Project, Central Valley Project, Alameda and San Joaquin Counties, CA...

78 FR 2354 - Approval and Promulgation of Air Quality Implementation Plans; Arkansas; Prevention of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-11

...) Prevention of Significant Deterioration (PSD) program updates the Arkansas SIP to incorporate by reference (IBR) requirements for the Federal PSD permitting program under EPA's November 29, 2005 Phase 2 8-hour Ozone Implementation rule. The November 6, 2012 proposed SIP revision to the Arkansas NSR PSD program...

78 FR 19596 - Approval and Promulgation of Air Quality Implementation Plans; Arkansas; Prevention of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-02

...) Prevention of Significant Deterioration (PSD) program updates the Arkansas SIP to incorporate by reference (IBR) requirements for the federal PSD permitting program under EPA's November 29, 2005 Phase 2 8-hour Ozone Implementation rule. The November 6, 2012, SIP revision to the Arkansas NSR PSD program provides...

21 CFR 178.3690 - Pentaerythritol adipate-stearate.

Code of Federal Regulations, 2011 CFR

2011-04-01

... adipic acid and stearic acid and its associated fatty acids (chiefly palmitic), with adipic acid comprising 14 percent and stearic acid and its associated acids (chiefly palmitic) comprising 71 percent of...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (2) Acid value...

21 CFR 178.3690 - Pentaerythritol adipate-stearate.

Code of Federal Regulations, 2010 CFR

2010-04-01

... adipic acid and stearic acid and its associated fatty acids (chiefly palmitic), with adipic acid comprising 14 percent and stearic acid and its associated acids (chiefly palmitic) comprising 71 percent of...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (2) Acid value...

40 CFR 61.18 - Incorporations by reference.

Code of Federal Regulations, 2012 CFR

2012-07-01

... (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS General Provisions § 61.18.... EPA's Air Docket at 1200 Pennsylvania Avenue, NW, Washington, DC 20460, or at the National Archives... 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr...

40 CFR 61.18 - Incorporations by reference.

Code of Federal Regulations, 2014 CFR

2014-07-01

... (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS General Provisions § 61.18.... EPA's Air Docket at 1200 Pennsylvania Avenue, NW, Washington, DC 20460, or at the National Archives... 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr...

21 CFR 177.2490 - Polyphenylene sulfide resins.

Code of Federal Regulations, 2014 CFR

2014-04-01

... titled “Oxygen Flask Combustion-Gravimetric Method for Determination of Sulfur in Organic Compounds... Park, MD 20740, or available for inspection at the National Archives and Records Administration (NARA....archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (1) Sulfur content: 28.2-29.1...

40 CFR 61.18 - Incorporations by reference.

Code of Federal Regulations, 2013 CFR

2013-07-01

... (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS General Provisions § 61.18.... EPA's Air Docket at 1200 Pennsylvania Avenue, NW, Washington, DC 20460, or at the National Archives... 202-741-6030, or go to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr...

48 CFR 334.203-70 - HHS solicitation provisions and contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... provisions and contract clauses. 334.203-70 Section 334.203-70 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management... Value Management System—Pre-Award IBR, in solicitations that will require the contractor to use an EVMS...

Effectiveness of Supplemental Kindergarten Vocabulary Instruction for English Learners: A Randomized Study of Immediate and Longer-Term Effects of Two Approaches

ERIC Educational Resources Information Center

Vadasy, Patricia F.; Sanders, Elizabeth A.; Nelson, J. Ron

2015-01-01

A two-cohort cluster randomized trial was conducted to estimate effects of small-group supplemental vocabulary instruction for at-risk kindergarten English learners (ELs). "Connections" students received explicit instruction in high-frequency decodable root words, and interactive book reading (IBR) students were taught the same words in…

48 CFR 1034.201 - Policy.

Code of Federal Regulations, 2011 CFR

2011-10-01

... CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 1034.201 Policy. (a) (1) An Earned Value Management System (EVMS) is required for major acquisitions for development/modernization/enhancement (DME... certified; and (4) Whether a Full Integrated Baseline Review (IBR) will be completed within 90 days when the...

10 CFR 429.4 - Materials incorporated by reference.

Code of Federal Regulations, 2013 CFR

2013-01-01

... Energy Efficiency and Renewable Energy, Building Technologies Program, 6th Floor, 950 L'Enfant Plaza, SW...) ANSI/AHAM DW-1-1992, American National Standard, Household Electric Dishwashers, approved February 6, 1992, IBR approved for § 429.19. (2) ANSI/AHAM DW-1-2010, Household Electric Dishwashers, (ANSI...

10 CFR 429.4 - Materials incorporated by reference.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Energy Efficiency and Renewable Energy, Building Technologies Program, 6th Floor, 950 L'Enfant Plaza, SW...) ANSI/AHAM DW-1-1992, American National Standard, Household Electric Dishwashers, approved February 6, 1992, IBR approved for § 429.19. (2) ANSI/AHAM DW-1-2010, Household Electric Dishwashers, (ANSI...

21 CFR 701.3 - Designation of ingredients.

Code of Federal Regulations, 2010 CFR

2010-04-01

....) Cosmetic Ingredient Dictionary, Second Ed., 1977 (available from the Cosmetic, Toiletry and Fragrance... revised monographs are published in supplements to this dictionary edition by July 18, 1980. Acid Black 2.../federal_register/code_of_federal_regulations/ibr_locations.html. (v) USAN and the USP dictionary of drug...

21 CFR 172.882 - Synthetic isoparaffinic petroleum hydrocarbons.

Code of Federal Regulations, 2014 CFR

2014-04-01

... American Society for Testing Materials, 100 Barr Harbor Dr., West Conshohocken, Philadelphia, PA 19428-2959.../code_of_federal_regulations/ibr_locations.html. Ultraviolet absorbance: 260-319 millimicrons—1.5 maximum. 320-329 millimicrons—0.08 maximum. 330-350 millimicrons—0.05 maximum. Nonvolatile residual: 0.002...

High fluence neutron radiation of plastic scintillators for the TileCal of the ATLAS detector.

NASA Astrophysics Data System (ADS)

Mdhluli, J. E.; Davydov, Yu I.; Baranov, V.; Mthembu, S.; Erasmus, R.; Jivan, H.; Khanye, N.; Tlou, H.; Tjale, B.; Starchenko, J.; Solovyanov, O.; Mellado, B.; Sideras-Haddad, E.

2017-09-01

We report on structural and optical properties of neutron irradiated plastic scintillators. These scintillators were subjected to a neutron beam with wide energy range of up to 10MeV and a neutron flux range of 1.2 × 1012 - 9.4 × 1012 n/cm 2 using the IBR-2 pulsed reactor at the Joint Institute for Nuclear Research in Dubna. A study between polyvinyl toluene based commercial scintillators EJ200, EJ208 and EJ260 as well as polystyrene based scintillator from Kharkov is conducted. Light transmission, Raman spectroscopy, fluorescence spectroscopy and light yield testing was performed to characterize the damage induced in the samples. Preliminary results from the tests performed indicate no change in the optical and structural properties of the scintillators. The polystyrene based scintillators were further subjected to a higher neutron flux range of 3.8 × 1012 - 1.8 × 1014 n/cm 2 using the IBR-2 pulsed reactor.

Analysis of the Capability to Effectively Design Complementary Metal Oxide Semiconductor Integrated Circuits.

DTIC Science & Technology

1984-12-01

LISTING TEtiPEkATURE = 27.8u DEG C ,WIDTH OUT=bo IC V(4)=5 OPTEL IbrS FIIISi (VTL=I Td -i ’ O8 SU-E5L=.11 .MUbEL N 1OS PriOS (VTu-1V TOA?5NM Uu=3@i NS’uB...INF6riTIO TEMERA~TURE = 27.88 DEG C t *ttlMGFETS 8M) M2 M3 M4 M5 M16 dr1QDEL FfiOS halOS PmoS Im1s mtos PrtOS JD i. di -2. bbd -li i. dtdi -2.fld-ll -2,i8d-I1...remain high VIN3 ? 8 Dc 5v VIN45 8DC 5V Tkki8 INS 28NS XPOT TRMN V0i1) V(4) W$,5V) *Erib lat***t06/84 ***it*** SPICE 2G.1 (I5OCT5u *tt’Itt~ td :14:28*#* d

Development of a virtual speaking simulator using Image Based Rendering.

PubMed

Lee, J M; Kim, H; Oh, M J; Ku, J H; Jang, D P; Kim, I Y; Kim, S I

2002-01-01

The fear of speaking is often cited as the world's most common social phobia. The rapid growth of computer technology has enabled the use of virtual reality (VR) for the treatment of the fear of public speaking. There are two techniques for building virtual environments for the treatment of this fear: a model-based and a movie-based method. Both methods have the weakness that they are unrealistic and not controllable individually. To understand these disadvantages, this paper presents a virtual environment produced with Image Based Rendering (IBR) and a chroma-key simultaneously. IBR enables the creation of realistic virtual environments where the images are stitched panoramically with the photos taken from a digital camera. And the use of chroma-keys puts virtual audience members under individual control in the environment. In addition, real time capture technique is used in constructing the virtual environments enabling spoken interaction between the subject and a therapist or another subject.

A field trial, of preshipment vaccination, with intranasal infectious bovine rhinotracheitis-parainfluenza-3 vaccines.

PubMed Central

Martin, W; Willson, P; Curtis, R; Allen, B; Acres, S

1983-01-01

A total of 849 calves, 278 controls, 335 vaccinated intranasally with IBR-PI3/TS and 236 vaccinated intranasally with IBR-PI3/PTC were studied in a field trial of preimmunization. All calves were vaccinated in Saskatchewan at least three weeks prior to shipment to feedlots. Four hundred and twenty six calves were not sold within eight weeks of vaccination; however, seven of these died within four weeks of vaccination. Treatment rates varied from 1.0% to 5.2%. There was no significant effect of vaccination on treatment rates. Similarly, there was no significant effect of vaccination in the 74 calves sold to feedlots in Saskatchewan. Three hundred and forty nine calves were sold to feedlots in Ontario. Two of these died from fibrinous pneumonia. Treatment rates varied from 1.7% to 33.3% in different feedlots, but there was no significant effect of vaccination on treatment rates. Therefore, preimmunization is unlikely to significantly reduce the overall treatment rate in calves entering feedlots. PMID:6315194

Availability of a fetal goat tongue cell line ZZ-R 127 for isolation of Foot-and-mouth disease virus (FMDV) from clinical samples collected from animals experimentally infected with FMDV.

PubMed

Fukai, Katsuhiko; Onozato, Hiroyuki; Kitano, Rie; Yamazoe, Reiko; Morioka, Kazuki; Yamada, Manabu; Ohashi, Seiichi; Yoshida, Kazuo; Kanno, Toru

2013-11-01

The availability of the fetal goat tongue cell line ZZ-R 127 for the isolation of Foot-and-mouth disease virus (FMDV) has not been evaluated using clinical samples other than epithelial suspensions. Therefore, in the current study, the availability of ZZ-R 127 cells for the isolation of FMDV was evaluated using clinical samples (e.g., sera, nasal swabs, saliva, feces, and oropharyngeal fluids) collected from animals experimentally infected with an FMDV isolate. Virus isolation rates for the ZZ-R 127 cells were statistically higher than those for the porcine kidney cell line (IB-RS-2) in experimental infections using cattle, goats, and pigs (P < 0.01). Virus titers in the ZZ-R 127 cells were also statistically higher than those in the IB-RS-2 cells. The availability of ZZ-R 127 cells for the isolation of FMDV not only from epithelial suspensions but also from other clinical samples was confirmed in the current study.

Seasonal changes in stress biomarkers of an exotic coastal species - Chaetopleura angulata (Polyplacophora) - Implications for biomonitoring.

PubMed

Madeira, Diana; Vinagre, Catarina; Mendonça, Vanessa; Diniz, Mário Sousa

2017-07-15

Knowledge on baseline values of stress biomarkers in natural conditions is urgent due to the need of reference values for monitoring purposes. Here we assessed the cellular stress response of the chiton Chaetopleura angulata in situ. Biomarkers commonly used in environmental monitoring (heat shock protein 70kDa, total ubiquitin, catalase, glutathione-S-transferase, superoxide-dismutase, lipid peroxidation) were analyzed in the digestive system, gills and muscle of C. angulata, under spring and summer conditions in order to assess seasonal tissue-specific responses. Season had an effect on all targeted organs, especially affecting the digestive system which displayed clear seasonal clusters. The respective Integrated Biomarker Response (IBR) showed a 7.2-fold seasonal difference. Muscle and gills showed similar IBRs between seasons making them appropriate organs to monitor chemical pollution as they were less responsive to seasonal variation. The most stable biomarkers in these organs were ubiquitin and superoxide-dismutase thus being reliable for monitoring purposes. Copyright © 2017 Elsevier Ltd. All rights reserved.

Immunogenicity of a modified-live virus vaccine against bovine viral diarrhea virus types 1 and 2, infectious bovine rhinotracheitis virus, bovine parainfluenza-3 virus, and bovine respiratory syncytial virus when administered intranasally in young calves.

PubMed

Xue, Wenzhi; Ellis, John; Mattick, Debra; Smith, Linda; Brady, Ryan; Trigo, Emilio

2010-05-14

The immunogenicity of an intranasally-administered modified-live virus (MLV) vaccine in 3-8 day old calves was evaluated against bovine viral diarrhea virus (BVDV) types 1 and 2, infectious bovine rhinotracheitis (IBR) virus, parainfluenza-3 (PI-3) virus and bovine respiratory syncytial virus (BRSV). Calves were intranasally vaccinated with a single dose of a multivalent MLV vaccine and were challenged with one of the respective viruses three to four weeks post-vaccination in five separate studies. There was significant sparing of diseases in calves intranasally vaccinated with the MLV vaccine, as indicated by significantly fewer clinical signs, lower rectal temperatures, reduced viral shedding, greater white blood cell and platelet counts, and less severe pulmonary lesions than control animals. This was the first MLV combination vaccine to demonstrate efficacy against BVDV types 1 and 2, IBR, PI-3 and BRSV in calves 3-8 days of age. Copyright 2010 Elsevier Ltd. All rights reserved.

Sistemas Correctores de Campo Para EL Telescopio Cassegrain IAC80

NASA Astrophysics Data System (ADS)

Galan, M. J.; Cobos, F. J.

1987-05-01

El proyecto de instrumentación de mayor importancia que ha tenido el Instituto de Astrofisica de Canarias en los últimos afios ha sido el diseflo y construcción del te1escopio IAC8O. Este requería del esfuerzo con junto en mec´nica, óptica y electrónica, lo que facilitó la estructuración y el crecimiento de los respectivos grupos de trabajo, que posteriormente se integraron en departamentos En su origen (1977), el telescopio IAC80 fue concebido como un sistema clásico tipo Cassegrain, con una razón focal F/i 1.3 para el sistema Casse grain y una razón focal F/20 para el sistema Coudé. Posteriormente, aunque se mantuvo la filosofia de que el sistema básico fuera el F/11.3, se consideró conveniente el diseño de secundarios para razones focales F/16 y F/32, y se eliminó el de F/20. Sin embargo, dada la importancia relativa que un foco estrictamente fotográfico tiene en un telescopio moderno, diseñado básicamente para fotometría fotoeléctrica y con un campo util mínimamente de 40 minutos de arco, se decídió Ilevar a cabo el diseño de un secundario F/8 con un sistema corrector de campo, pero que estuviera formado únicamente por lentes con superficies esféricas para que asl su construcción fuera posible en España ó en México. La creciente utilización de detectores bidimensionales para fines de investigación astron6mica y la viabilidad de que en un futuro cercano éstos tengan un área sensible cada vez mayor, hicieron atractiva la idea de tener diseñado un sistema corrector de campo para el foco primario (F/3), con un campo útil mínimo de un grado, y también con la limitante de que sus componentes tuvieron sólamente supérficies esféricas. Ambos diseños de los sis-temas correctores de campo se llevaron a cabo, en gran medida, como parte de un proyecto de colaboración e intercambio en el área de diseño y evaluación de sistemas ópticos.

Quantum fluctuations increase the self-diffusive motion of para-hydrogen in narrow carbon nanotubes.

PubMed

Kowalczyk, Piotr; Gauden, Piotr A; Terzyk, Artur P; Furmaniak, Sylwester

2011-05-28

Quantum fluctuations significantly increase the self-diffusive motion of para-hydrogen adsorbed in narrow carbon nanotubes at 30 K comparing to its classical counterpart. Rigorous Feynman's path integral calculations reveal that self-diffusive motion of para-hydrogen in a narrow (6,6) carbon nanotube at 30 K and pore densities below ∼29 mmol cm(-3) is one order of magnitude faster than the classical counterpart. We find that the zero-point energy and tunneling significantly smoothed out the free energy landscape of para-hydrogen molecules adsorbed in a narrow (6,6) carbon nanotube. This promotes a delocalization of the confined para-hydrogen at 30 K (i.e., population of unclassical paths due to quantum effects). Contrary the self-diffusive motion of classical para-hydrogen molecules in a narrow (6,6) carbon nanotube at 30 K is very slow. This is because classical para-hydrogen molecules undergo highly correlated movement when their collision diameter approached the carbon nanotube size (i.e., anomalous diffusion in quasi-one dimensional pores). On the basis of current results we predict that narrow single-walled carbon nanotubes are promising nanoporous molecular sieves being able to separate para-hydrogen molecules from mixtures of classical particles at cryogenic temperatures. This journal is © the Owner Societies 2011

Preparation of ortho-para ratio controlled D{sub 2} gas for muon-catalyzed fusion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Imao, H.; Ishida, K.; Matsuzaki, T.

2008-05-15

A negative muon in hydrogen targets, e.g., D{sub 2} or D-T mixture, can catalyze nuclear fusions following a series of atomic processes involving muonic hydrogen molecular formation (muon-catalyzed fusion, {mu}CF). The ortho-para state of D{sub 2} is a crucial parameter not only for enhancing the fusion rate but also to precisely investigate various muonic atom processes. We have developed a system for controlling and measuring the ortho-para ratio of D{sub 2} gas for {mu}CF experiments. We successfully collected para-enriched D{sub 2} without using liquid-hydrogen coolant. Ortho-enriched D{sub 2} was also obtained by using a catalytic conversion method with a mixturemore » of chromium oxide and alumina. The ortho-para ratio of D{sub 2} gas was measured with a compact Raman spectroscopy system. We produced large volume (5-30 l at STP), high-purity (less than ppm high-Z contaminant) D{sub 2} targets with a wide range of ortho-para ratios (ortho 20%-99%). By using the ortho-para controlled D{sub 2} in {mu}CF experiments, we observed the dependence of {mu}CF phenomena on the ortho-para ratio.« less

Relative Contributions of Agricultural Drift, Para-Occupational ...

EPA Pesticide Factsheets

Background: Increased pesticide concentrations in house dust in agricultural areas have been attributed to several exposure pathways, including agricultural drift, para-occupational, and residential use. Objective: To guide future exposure assessment efforts, we quantified relative contributions of these pathways using meta-regression models of published data on dust pesticide concentrations. Methods: From studies in North American agricultural areas published from 1995-2015, we abstracted dust pesticide concentrations reported as summary statistics (e.g., geometric means (GM)). We analyzed these data using mixed-effects meta-regression models that weighted each summary statistic by its inverse variance. Dependent variables were either the log-transformed GM (drift) or the log-transformed ratio of GMs from two groups (para-occupational, residential use). Results: For the drift pathway, predicted GMs decreased sharply and nonlinearly, with GMs 64% lower in homes 250 m versus 23 m from fields (inter-quartile range of published data) based on 52 statistics from 7 studies. For the para-occupational pathway, GMs were 2.3 times higher (95% confidence interval [CI]: 1.5-3.3; 15 statistics, 5 studies) in homes of farmers who applied pesticides more versus less recently or frequently. For the residential use pathway, GMs were 1.3 (95%CI: 1.1-1.4) and 1.5 (95%CI: 1.2-1.9) times higher in treated versus untreated homes, when the probability that a pesticide was used for

Sistemas Correctores de Campo Para EL Telescopio Ritchey-Chretien UNAM212

NASA Astrophysics Data System (ADS)

Cobos, F. J.; Galan, M. J.

1987-05-01

El telescopio UNAM2l2 fue inaugurado hace siete años y concebido para trabajar en las razones focales: f/7.5, F/13.5, F/27 y F/98. El diseño Ritchey-Chretién corresponde a la razón focal F/7.5 y el foco primario (F/2.286) no se consideró como utilizable para fotografía directa. En el Instituto de Astronomía de la UNAM, se diseñó y construyó un sistema corrector de campo para la razón focal F/7.5, que actualmente está en funcionamiento. Dentro de un programa de colaboración en diseflo y evaluación de sistemas ópticos, entre el Instituto de Astrofísica de Canarias y el Instituto de Astronomía de la UNAM, decidimos intentar el diseño de una correctora de campo para el foco primario del tȩlescopio UNAM212 bajo la consideración de que no son insalvables los problemas que implicaría su instalación y de que es muy posible que, en un futuro relativamente cercano, podamom tener un detector bidimenmional tipo Mepsicrón cuya área sensible haga tentadora la idea de construir la cámara directa para foco primario

Para Sport Athletic Identity from Competition to Retirement: A Brief Review and Future Research Directions.

PubMed

Guerrero, Michelle; Martin, Jeffrey

2018-05-01

The primary purpose of this article is to review the literature on para sport athletic identity and provide avenues for future research direction. First, the authors briefly describe the existing quantitative and qualitative research on para sport athletic identity and, thereby, illustrate the complexities para sport athletes experience regarding the way they describe their participation in competitive sport. Next, the authors describe how para sport athletes with acquired permanent disabilities and congenital disabilities face similar, yet unique, identity-related challenges. Finally, the authors argue that future researchers should consider examining para sport athletes' identity through narrative identity. Copyright © 2018 Elsevier Inc. All rights reserved.

Capacitación-acción participativa: una experiencia de 24 años en las comunidades rurales de Oaxaca, México.

PubMed

Ysunza, Alberto M; Diez-Urdanivia, Silvia; Pérez-Gil, Sara E

2017-12-01

Resumen: En este artículo presentamos el proyecto de capacitación llevado a cabo en comunidades de la sierra y costa de Oaxaca, México, desde 1991, por el Centro de Capacitación Integral para Promotores Comunitarios (CECIPROC). La decisión de hacer este trabajo en Oaxaca responde a que ese estado ocupa uno de los primeros lugares de marginación y de desnutrición en menores de 5 años. El objetivo es describir un modelo de capacitación y compartir parte de las experiencias derivadas, tanto del modelo como del trabajo realizado en las distintas áreas (nutrición y alimentación, salud comunitaria, ecología y etnobotánica, y educación y organización), por promotores mujeres y hombres en sus comunidades. La experiencia obtenida en 24 años muestra la factibilidad técnica y social del proyecto en el ámbito de la salud, el reconocimiento social del proyecto del CECIPROC como un organismo civil que ha aportado alternativas como solución a la problemática de salud, el hacer suyo el proyecto por algunos promotores y los diferentes obstáculos a los que se ha enfrentado. Enfatizamos el hecho de que la situación socioeconómica y política prevaleciente en el estado de Oaxaca es una limitante para el buen desarrollo de los programas colectivos de salud, e insistimos en la necesidad de compartir nuestras experiencias para que puedan ser utilizadas en la planificación y ejecución de otros proyectos.

Clinical Validation of the Nursing Outcome "Swallowing Status" in People with Stroke: Analysis According to the Classical and Item Response Theories.

PubMed

Oliveira-Kumakura, Ana Railka de Souza; de Araujo, Thelma Leite; Costa, Alice Gabrielle de Sousa; Cavalcante, Tahissa Frota; Lopes, Marcos Venícios de Oliveira; Carvalho, Emilia Campos

2017-09-19

To validate clinically the nursing outcome "Swallowing status". The adjustment of the nursing outcome was investigated according to the Classical and Item Response Theories. The models were compared regarding information loss, goodness-of-fit, and differential item functioning. Stability and internal consistency were examined. The nursing outcome has the best fit in the generalized partial credit model with different discrimination parameters. Strong correlations among the scores of each indicator were observed. There was no differential item functioning of the outcome indicators. The scale presented high internal consistency (Cronbach's α = .954) and stability (and > .800). This study presents a valid nursing outcome. Most accurate monitoring of sensitivity to an intervention. Validar clinicamente o resultado de enefermagem "Estado da Deglutição". MÉTODOS: O ajustamento do resultado foi investigado de acordo com as teorias Clássica e de Resposta ao Item. Os modelos foram comparados assumindo parâmetros de itens cruzados de igual discriminação. Investigaram-se as propriedades de bondade do ajuste, funcionamento diferencial dos itens, estabilidade e consistência interna. O resultado se ajustou melhor a partir do Modelo de crédito parcial generalizado, o qual demonstrou unidimensionalidade do resultado e forte correlação entre os escores de cada indicador. Não houve funcionamento diferencial dos indicadores. A consistência interna para a escala global (Cronbach's α = .954) e a estabilidade (>.800) mantiveram-se elevadas. CONCLUSÃO: O estudo apresenta um resultado de enfermagem válido. RELEVÂNCIA PARA A PRÁTICA CLÍNICA: Maior acurácia para monitorar a sensibilidade da intervenção. © 2017 NANDA International, Inc.

Conceptuaciones de los estudiantes de las facultades de educacion y ciencias naturales de la Universidad de Puerto Rico, recinto de Rio Piedras, acerca de la ciencia y la pseudociencia

NASA Astrophysics Data System (ADS)

Reyes Medina, Hector A.

Esta investigacion describe las conceptuaciones de los estudiantes de tercer ano o mas a nivel de bachillerato de los programas de Educacion en Ciencia y Ciencias Naturales de la Universidad de Puerto Rico, Recinto de Rio Piedras, acerca de lo establecido en la literatura para distinguir el conocimiento cientifico de las creencias pseudocientificas. Este estudio se guio por un diseno tipo encuesta transversal que permitio conocer de manera consistente las conceptuaciones de los estudiantes encuestados acerca de la Ciencia y la Pseudociencia. Ademas, permitio desarrollar inferencias estadisticas relacionadas a la poblacion de estudio, sus conceptuaciones y su inclinacion teorica en torno al Realismo y al Racionalismo cientifico moderados. El instrumento utilizado fue el Cuestionario acerca de las concepciones de la ciencia y la pseudocienca en estudiantes universitarios, Reyes (2015). Este cuestionario fue validado mediante la recopilacion de diversas fuentes de evidencias, entre estas se encuentran las evidencias basadas en el contenido, el proceso de respuesta, la estructura interna y de constructo. Tambien, se calculo el Alfa de Crombach para la escala total y para cada componente y se realizo un analisis de factores que demostro la presencia de seis componentes claramente definidos de acuerdo a lo esperado sobre las caracteristicas originales del instrumento. Las estadisticas utilizadas fueron descriptivas. Participaron 302 alumnos, de las facultades de educacion y ciencias naturales. Se encontro que las conceptuaciones de los estudiantes de ambas facultades se inclinan en un 66.2% a favor con lo establecido en el modelo teorico en torno al Realismo y al Racionalismo cientifico moderados. Sin embargo, aun hay un 33.8% de los estudiantes de ambas facultades que poseen conceptuaciones distintas al modelo teorico propuesto.

Astronomia para/com crianças carentes em Limeira

NASA Astrophysics Data System (ADS)

Bretones, P. S.; Oliveira, V. C.

2003-08-01

Em 2001, o Instituto Superior de Ciências Aplicadas (ISCA Faculdades de Limeira) iniciou um projeto pelo qual o Observatório do Morro Azul empreendeu uma parceria com o Centro de Promoção Social Municipal (CEPROSOM), instituição mantida pela Prefeitura Municipal de Limeira para atender crianças e adolescentes carentes. O CEPROSOM contava com dois projetos: Projeto Centro de Convivência Infantil (CCI) e Programa Criança e Adolescente (PCA), que atendiam crianças e adolescentes em Centros Comunitários de diversas áreas da cidade. Esses projetos têm como prioridades estabelecer atividades prazerosas para as crianças no sentido de retirá-las das ruas. Assim sendo, as crianças passaram a ter mais um tipo de atividade - as visitas ao observatório. Este painel descreve as várias fases do projeto, que envolveu: reuniões de planejamento, curso de Astronomia para as orientadoras dos CCIs e PCAs, atividades relacionadas a visitas das crianças ao Observatório, proposta de construção de gnômons e relógios de Sol nos diversos Centros Comunitários de Limeira e divulgação do projeto na imprensa. O painel inclui discussões sobre a aprendizagem de crianças carentes, relatos que mostram a postura das orientadoras sobre a pertinência do ensino de Astronomia, relatos do monitor que fez o atendimento no Observatório e o que o número de crianças atendidas representou para as atividades da instituição desde o início de suas atividades e, em particular, em 2001. Os resultados são baseados na análise de relatos das orientadoras e do monitor do Observatório, registros de visitas e matérias da imprensa local. Conclui com uma avaliação do que tal projeto representou para as Instituições participantes. Para o Observatório, em particular, foi feita uma análise com relação às outras modalidades de atendimentos que envolvem alunos de escolas e público em geral. Também é abordada a questão do compromisso social do Observatório na educação do

49 CFR 178.277 - Requirements for the design, construction, inspection and testing of portable tanks intended for...

Code of Federal Regulations, 2011 CFR

2011-10-01

... design pressure in the ASME Code, Section VIII (IBR, see § 171.7 of this subchapter). Holding time is the... 49 Transportation 3 2011-10-01 2011-10-01 false Requirements for the design, construction... FOR PACKAGINGS Specifications for Portable Tanks § 178.277 Requirements for the design, construction...

49 CFR 178.277 - Requirements for the design, construction, inspection and testing of portable tanks intended for...

Code of Federal Regulations, 2012 CFR

2012-10-01

... design pressure in the ASME Code, Section VIII (IBR, see § 171.7 of this subchapter). Holding time is the... 49 Transportation 3 2012-10-01 2012-10-01 false Requirements for the design, construction... FOR PACKAGINGS Specifications for Portable Tanks § 178.277 Requirements for the design, construction...

49 CFR 178.277 - Requirements for the design, construction, inspection and testing of portable tanks intended for...

Code of Federal Regulations, 2014 CFR

2014-10-01

... design pressure in the ASME Code, Section VIII (IBR, see § 171.7 of this subchapter). Holding time is the... 49 Transportation 3 2014-10-01 2014-10-01 false Requirements for the design, construction... FOR PACKAGINGS Specifications for Portable Tanks § 178.277 Requirements for the design, construction...

49 CFR 178.277 - Requirements for the design, construction, inspection and testing of portable tanks intended for...

Code of Federal Regulations, 2010 CFR

2010-10-01

... design pressure in the ASME Code, Section VIII (IBR, see § 171.7 of this subchapter). Holding time is the... 49 Transportation 2 2010-10-01 2010-10-01 false Requirements for the design, construction... FOR PACKAGINGS Specifications for Portable Tanks § 178.277 Requirements for the design, construction...

49 CFR 178.277 - Requirements for the design, construction, inspection and testing of portable tanks intended for...

Code of Federal Regulations, 2013 CFR

2013-10-01

... design pressure in the ASME Code, Section VIII (IBR, see § 171.7 of this subchapter). Holding time is the... 49 Transportation 3 2013-10-01 2013-10-01 false Requirements for the design, construction... FOR PACKAGINGS Specifications for Portable Tanks § 178.277 Requirements for the design, construction...

Effects of Emergent Literacy Interventions for Preschoolers with Autism Spectrum Disorder

ERIC Educational Resources Information Center

Hudson, Roxanne F.; Sanders, Elizabeth A.; Greenway, Rosanne; Xie, Sharon; Smith, Maya; Gasamis, Colin; Martini, Jay; Schwartz, Ilene; Hackett, Jacob

2017-01-01

Combining data from a series of three planned consecutive randomized controlled trials, the present study investigates two literacy interventions for preschool children with autism spectrum disorder. For the first cohort, children were randomized to interactive book reading (IBR; treatment) or business as usual (BAU; control); in Cohort 2,…

40 CFR 1048.810 - What materials does this part reference?

Code of Federal Regulations, 2011 CFR

2011-07-01

... in this section have been incorporated by reference into this part. The Director of the Federal... may inspect copies at the U.S. EPA, Air and Radiation Docket and Information Center, 1301 Constitution...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (a) SAE...

40 CFR 310.23 - How will EPA rank approved requests?

Code of Federal Regulations, 2011 CFR

2011-07-01

..., 88-NE-SC, 88-W-SC, 88-WNC-SC, March 1990. The Director of the Federal Register has approved this... Bureau of the Census, Office of Public Affairs, Department of Commerce, Constitution Avenue, NE...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) Larger...

40 CFR 1045.810 - What materials does this part reference?

Code of Federal Regulations, 2012 CFR

2012-07-01

... listed in this section have been incorporated by reference into this part. The Director of the Federal... may inspect copies at the U.S. EPA, Air and Radiation Docket and Information Center, 1301 Constitution...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (a) SAE...

40 CFR 310.23 - How will EPA rank approved requests?

Code of Federal Regulations, 2010 CFR

2010-07-01

..., 88-NE-SC, 88-W-SC, 88-WNC-SC, March 1990. The Director of the Federal Register has approved this... Bureau of the Census, Office of Public Affairs, Department of Commerce, Constitution Avenue, NE...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) Larger...

40 CFR 310.23 - How will EPA rank approved requests?

Code of Federal Regulations, 2014 CFR

2014-07-01

..., 88-NE-SC, 88-W-SC, 88-WNC-SC, March 1990. The Director of the Federal Register has approved this... Bureau of the Census, Office of Public Affairs, Department of Commerce, Constitution Avenue, NE...: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. (c) Larger...

49 CFR 179.300-10 - Postweld heat treatment.

Code of Federal Regulations, 2011 CFR

2011-10-01

... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Multi-Unit Tank Car Tanks (Classes DOT-106A and 110AW) § 179.300-10 Postweld heat treatment... as a unit in compliance with the requirements of AAR Specifications for Tank Cars, appendix W (IBR...

49 CFR 179.100-12 - Manway nozzle, cover and protective housing.

Code of Federal Regulations, 2014 CFR

2014-10-01

...) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120... with the requirements of AAR Specifications for Tank Cars, appendix E, Figure E10 (IBR, see § 171.7 of...

49 CFR 179.100-12 - Manway nozzle, cover and protective housing.

Code of Federal Regulations, 2010 CFR

2010-10-01

... HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120... with the requirements of AAR Specifications for Tank Cars, appendix E, Figure E10 (IBR, see § 171.7 of...

49 CFR 179.100-12 - Manway nozzle, cover and protective housing.

Code of Federal Regulations, 2011 CFR

2011-10-01

...) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120... with the requirements of AAR Specifications for Tank Cars, appendix E, Figure E10 (IBR, see § 171.7 of...

49 CFR 179.300-10 - Postweld heat treatment.

Code of Federal Regulations, 2012 CFR

2012-10-01

... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Multi-Unit Tank Car Tanks (Classes DOT-106A and 110AW) § 179.300-10 Postweld heat treatment... as a unit in compliance with the requirements of AAR Specifications for Tank Cars, appendix W (IBR...

49 CFR 179.100-12 - Manway nozzle, cover and protective housing.

Code of Federal Regulations, 2013 CFR

2013-10-01

...) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) SPECIFICATIONS FOR TANK CARS Specifications for Pressure Tank Car Tanks (Classes DOT-105, 109, 112, 114 and 120... with the requirements of AAR Specifications for Tank Cars, appendix E, Figure E10 (IBR, see § 171.7 of...

76 FR 41705 - Approval and Promulgation of Implementation Plans; New York; Revised Format of Materials Being...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-15

... the APA, since the reorganization and codification of the revised format for denoting IBR of the state... Promulgation of Implementation Plans; New York; Revised Format of Materials Being Incorporated by Reference... Environmental Protection Agency (EPA) is revising the format of materials submitted by the State of New York...

77 FR 76417 - Approval and Promulgation of Air Quality Implementation Plans; Idaho; Update to Materials...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-28

... result of consultations between EPA and the Office of the Federal Register (OFR). The description of the revised SIP document, IBR procedures and ``Identification of plan'' format are discussed in further detail... the ``good cause'' exemption in section 553(b)(3)(B) of the Administrative Procedures Act (APA) [[Page...

46 CFR 148.8 - Incorporation by reference.

Code of Federal Regulations, 2011 CFR

2011-10-01

... http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html. Also, it is... 7611, http://www.imo.org. (1) International Maritime Solid Bulk Cargoes Code and Supplement, 2009..., New York, NY 10017, (800) 253-9646, http://unp.un.org. (1) Recommendations on the Transport of...

10 CFR 431.303 - Materials incorporated by reference.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Transmission Properties by Means of the Heat Flow Meter Apparatus, approved May 1, 2004, IBR approved for § 431... insulation products for buildings—Factory made products of extruded polystyrene foam (XPS)—Specification..., (“DIN EN 13165”), Thermal insulation products for buildings—Factory made rigid polyurethane foam (PUR...

30 CFR 870.20 - How to calculate excess moisture in LOW-rank coals.

Code of Federal Regulations, 2012 CFR

2012-07-01

.../code_of_federal_regulations/ibr_locations.html. (a)(1) Calculate the excess moisture percentage using... coals. 870.20 Section 870.20 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT... COAL PRODUCTION REPORTING § 870.20 How to calculate excess moisture in LOW-rank coals. Here are the...

30 CFR 75.322 - Harmful quantities of noxious gases.

Code of Federal Regulations, 2014 CFR

2014-07-01

..._federal_regulations/ibr_locations.html. [61 FR 26442, May 28, 1996, as amended at 67 FR 38386, June 4... Section 75.322 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Ventilation § 75.322 Harmful...

30 CFR 870.20 - How to calculate excess moisture in LOW-rank coals.

Code of Federal Regulations, 2014 CFR

2014-07-01

.../code_of_federal_regulations/ibr_locations.html. (a)(1) Calculate the excess moisture percentage using... coals. 870.20 Section 870.20 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT... COAL PRODUCTION REPORTING § 870.20 How to calculate excess moisture in LOW-rank coals. Here are the...

30 CFR 870.20 - How to calculate excess moisture in LOW-rank coals.

Code of Federal Regulations, 2011 CFR

2011-07-01

.../code_of_federal_regulations/ibr_locations.html. (a)(1) Calculate the excess moisture percentage using... coals. 870.20 Section 870.20 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT... COAL PRODUCTION REPORTING § 870.20 How to calculate excess moisture in LOW-rank coals. Here are the...

30 CFR 75.322 - Harmful quantities of noxious gases.

Code of Federal Regulations, 2012 CFR

2012-07-01

..._federal_regulations/ibr_locations.html. [61 FR 26442, May 28, 1996, as amended at 67 FR 38386, June 4... Section 75.322 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Ventilation § 75.322 Harmful...

48 CFR 34.203 - Solicitation provisions and contract clause.

Code of Federal Regulations, 2012 CFR

2012-10-01

... REGULATION SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 34.203... substantially the same as the provision at FAR 52.234-2, Notice of Earned Value Management System - Pre-Award... System (EVMS) and for which the Government requires an Integrated Baseline Review (IBR) prior to award...

48 CFR 34.203 - Solicitation provisions and contract clause.

Code of Federal Regulations, 2010 CFR

2010-10-01

... REGULATION SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 34.203... substantially the same as the provision at FAR 52.234-2, Notice of Earned Value Management System - Pre-Award... System (EVMS) and for which the Government requires an Integrated Baseline Review (IBR) prior to award...

48 CFR 34.203 - Solicitation provisions and contract clause.

Code of Federal Regulations, 2014 CFR

2014-10-01

... REGULATION SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 34.203... substantially the same as the provision at FAR 52.234-2, Notice of Earned Value Management System - Pre-Award... System (EVMS) and for which the Government requires an Integrated Baseline Review (IBR) prior to award...

48 CFR 34.203 - Solicitation provisions and contract clause.

Code of Federal Regulations, 2013 CFR

2013-10-01

... REGULATION SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 34.203... substantially the same as the provision at FAR 52.234-2, Notice of Earned Value Management System - Pre-Award... System (EVMS) and for which the Government requires an Integrated Baseline Review (IBR) prior to award...

48 CFR 34.203 - Solicitation provisions and contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

... REGULATION SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION Earned Value Management System 34.203... substantially the same as the provision at FAR 52.234-2, Notice of Earned Value Management System - Pre-Award... System (EVMS) and for which the Government requires an Integrated Baseline Review (IBR) prior to award...

77 FR 30265 - Notice of Submission for OMB Review; Federal Student Aid; Direct Loan Income Contingent Repayment...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-22

... Income Contingent Repayment Plan Alternative Documentation of Income SUMMARY: This form serves as the means by which a borrower who is repaying Direct Loan Program loans under the Income-Contigent Repayment (ICR) Plan or the Income-Based Repayment (IBR) Plan provides the U.S. Department of Education (the...

76 FR 77111 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-12

..., 6500 South MacArthur Blvd., Oklahoma City, OK 73169 or 4. The National Archives and Records... to: http://www.archives.gov/federal_register/code_of_federal_regulations/ibr_locations.html..., Amdt 3D, CANCELLED Fort Hood/Killeen, TX, Robert Gray AAF, RADAR-1, Orig New Market, VA, New Market...

21 CFR 172.380 - Vitamin D 3.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION Special Dietary and Nutritional Additives § 172.../federal-register/cfr/ibr-locations.html. (c) The additive may be used as follows: (1) At levels not to...

38 CFR 17.1 - Incorporation by reference.

Code of Federal Regulations, 2014 CFR

2014-07-01

..., Standard for the Installation of Sprinkler Systems (2010 edition), IBR approved for § 17.74. (5) NFPA 13D, Standard for the Installation of Sprinkler Systems in One- and Two-Family Dwellings and Manufactured Homes... the National Fire Protection Association, 1 Batterymarch Park, Quincy, MA 02269. (For ordering...

38 CFR 17.1 - Incorporation by reference.

Code of Federal Regulations, 2012 CFR

2012-07-01

..., Standard for the Installation of Sprinkler Systems (2010 edition), IBR approved for § 17.74. (5) NFPA 13D, Standard for the Installation of Sprinkler Systems in One- and Two-Family Dwellings and Manufactured Homes... the National Fire Protection Association, 1 Batterymarch Park, Quincy, MA 02269. (For ordering...

38 CFR 17.1 - Incorporation by reference.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., Standard for the Installation of Sprinkler Systems (2010 edition), IBR approved for § 17.74. (5) NFPA 13D, Standard for the Installation of Sprinkler Systems in One- and Two-Family Dwellings and Manufactured Homes... the National Fire Protection Association, 1 Batterymarch Park, Quincy, MA 02269. (For ordering...

14 CFR 171.321 - DME and marker beacon performance requirements.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false DME and marker beacon performance... (MLS) § 171.321 DME and marker beacon performance requirements. (a) The DME equipment must meet the..._regulations/ibr_locations.html. (b) MLS marker beacon equipment must meet the performance requirements...

40 CFR 94.5 - Reference materials.

Code of Federal Regulations, 2012 CFR

2012-07-01

... available for inspection at the National Archives and Records Administration (NARA). For information on the.../code_of_federal_regulations/ibr_locations.html. In addition, these materials are available from the...-7611, or at http://www.imo.org. (1) Resolution 2—Technical Code on Control of Emission of Nitrogen...

40 CFR 94.5 - Reference materials.

Code of Federal Regulations, 2014 CFR

2014-07-01

... available for inspection at the National Archives and Records Administration (NARA). For information on the.../code_of_federal_regulations/ibr_locations.html. In addition, these materials are available from the...-7611, or at http://www.imo.org. (1) Resolution 2—Technical Code on Control of Emission of Nitrogen...

40 CFR 94.5 - Reference materials.

Code of Federal Regulations, 2011 CFR

2011-07-01

..., Washington, DC 20460 or at the National Archives and Records Administration (NARA). For information on the.../code_of_federal_regulations/ibr_locations.html. (a) ASTM material. Table 1 of § 94.5 lists material... internal combustion engines—Exhaust emission measurement—Part 1: Test-bed measurement of gaseous and...