Sample records for identify promising technologies

  1. VLSI Technology: Impact and Promise. Identifying Emerging Issues and Trends in Technology for Special Education.

    ERIC Educational Resources Information Center

    Bayoumi, Magdy

    As part of a 3-year study to identify emerging issues and trends in technology for special education, this paper addresses the implications of very large scale integrated (VLSI) technology. The first section reviews the development of educational technology, particularly microelectronics technology, from the 1950s to the present. The implications…

  2. The promise of advanced technology for future air transports

    NASA Technical Reports Server (NTRS)

    Bower, R. E.

    1978-01-01

    Progress in all weather 4-D navigation and wake vortex attenuation research is discussed and the concept of time based metering of aircraft is recommended for increased emphasis. The far term advances in aircraft efficiency were shown to be skin friction reduction and advanced configuration types. The promise of very large aircraft, possibly all wing aircraft is discussed, as is an advanced concept for an aerial relay transportation system. Very significant technological developments were identified that can improve supersonic transport performance and reduce noise. The hypersonic transport was proposed as the ultimate step in air transportation in the atmosphere. Progress in the key technology areas of propulsion and structures was reviewed. Finally, the impact of alternate fuels on future air transports was considered and shown not to be a growth constraint.

  3. The Promise of Technology for College Instruction: From Drill and Practice to Avatars

    ERIC Educational Resources Information Center

    Kuhlenschmidt, Sally; Kacer, Barbara

    2010-01-01

    Technology and its uses have undergone significant change in the past several decades. Although the technology of 2010 has changed in ways unimaginable in 1960, the promise of technology today is similar to the promise of technology then. The achievement of student learning seems more likely to lie in the minds of the people who use the technology…

  4. Assistive technology and learning disabilities: today's realities and tomorrow's promises.

    PubMed

    Lewis, R B

    1998-01-01

    Many forms of technology, both "high" and "low," can help individuals with learning disabilities capitalize on their strengths and bypass, or compensate for, their disabilities. This article surveys the current status of assistive technology for this population and reflects on future promises and potential problems. In addition, a model is presented for conceptualizing assistive technology in terms of the types of barriers it helps persons with disabilities to surmount. Several current technologies are described and the research supporting their effectiveness reviewed: word processing, computer-based instruction in reading and other academic areas, interactive videodisc interventions for math, and technologies for daily life. In conclusion, three themes related to the future success of assistive technology applications are discussed: equity of access to technology; ease of technology, use; and emergent technologies, such as virtual reality.

  5. Learning Technologies and Their Impact on Science Education: Delivering the Promise.

    ERIC Educational Resources Information Center

    Parker, Lesley

    2000-01-01

    This keynote address focuses on the particular manifestation of 'learning technologies' broadly as 'information and communications technologies' (ICT). Discusses these in relation to their contribution to an effective digital K-12 curriculum and effective online learning by students in science. Examines "delivering the promise" of ICT for science…

  6. PROMISE AND PLAUSIBILITY: HEALTH TECHNOLOGY ADOPTION DECISIONS WITH LIMITED EVIDENCE.

    PubMed

    Campbell, Bruce; Knox, Paul

    2016-01-01

    The adoption of new medical devices and diagnostics is often hampered by lack of published evidence which makes conventional health technology assessment (HTA) difficult. We now have 5 years' experience of the Medical Technologies Advisory Committee of the National Institute for Health and Care Excellence (NICE) in the United Kingdom, addressing this problem. This committee assesses devices and diagnostics against claims of advantage, to produce guidance on adoption for the health service. We have reflected on the practical, technical, and intellectual processes we have used in developing guidance for the health service. When scientific and clinical evidence is sparse, promise and plausibility play an increased part in decision-making. Drivers of promise include a clear design and mechanism of action, the possibility of radical improvement in care and/or resource use, and improving health outcomes for large numbers of patients. Plausibility relates to judgements about the whether the promise is likely to be delivered in a "real world" setting. Promise and plausibility need to be balanced against the amount of evidence available. We examine the influence they may have on decision-making compared with other factors such as risk and cost. Decisions about adoption of new devices and diagnostics with little evidence are influenced by judgements of their promise and the plausibility of claims that they will provide benefits in a real-world setting. This kind of decision making needs to be transparent and this article explains how these influences can be balanced against the use of more familiar criteria.

  7. The Technology Fix: The Promise and Reality of Computers in Our Schools

    ERIC Educational Resources Information Center

    Pflaum, William D.

    2004-01-01

    During the technology boom of the 1980s and 1990s, computers seemed set to revolutionize education. Do any of these promises sound familiar? (1) Technology would help all students learn better, thanks to multimedia programs capable of adapting to individual needs, learning styles, and skill levels; (2) Technology would transform the teacher's role…

  8. Promises of advanced technology realized at Martin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Swanekamp, R.

    1996-09-01

    The 2,488-MW Martin station is a gas/oil-fired facility that embodies today`s demand for flexible operations, technological advances, and reduced production costs. Martin station first rose up from the Everglades in the early 1980s, with the construction of two 814-MW oil-fired steam plants, Units 1 and 2. Natural-gas-firing capability was added to the balanced-draft, natural-circulation boilers in 1986, increasing the station`s fuel flexibility. Martin then leaped into the headlines in the early 1990s when it added combined-cycle (CC) Units 3 and 4. With this 860-MW expansion, FP and L boldly became the fleet leader for the advanced, 2350F-class 7FA gas turbines.more » Further pushing he technology envelope, the CC includes a three-pressure reheat steam system that raises net plant efficiency for Units 3 and 4 to 54%, on a lower-heating-value (LHV) basis. Incorporating the reheat cycle required significant redesign of the gas-turbine/heat-recovery steam generator (HRSG) train, in order to maintain a rapid startup capability without exceeding metallurgical limits. Perhaps even more important than the technological achievements, Martin stands out from the crowd for its people power, which ensured that the promises of advanced technology actually came to fruition. This station`s aggressive, empowered O and M team shows that you can pioneer technology, reduce operating costs, and deliver high availability--all at the same time.« less

  9. Promising Electric Aircraft Drive Systems

    NASA Technical Reports Server (NTRS)

    Dudley, Michael R.

    2010-01-01

    An overview of electric aircraft propulsion technology performance thresholds for key power system components is presented. A weight comparison of electric drive systems with equivalent total delivered energy is made to help identify component performance requirements, and promising research and development opportunities.

  10. [Advances of studies on new technology and method for identifying traditional Chinese medicinal materials].

    PubMed

    Chen, Shilin; Guo, Baolin; Zhang, Guijun; Yan, Zhuyun; Luo, Guangming; Sun, Suqin; Wu, Hezhen; Huang, Linfang; Pang, Xiaohui; Chen, Jianbo

    2012-04-01

    In this review, the authors summarized the new technologies and methods for identifying traditional Chinese medicinal materials, including molecular identification, chemical identification, morphological identification, microscopic identification and identification based on biological effects. The authors introduced the principle, characteristics, application and prospect on each new technology or method and compared their advantages and disadvantages. In general, new methods make the result more objective and accurate. DNA barcoding technique and spectroscopy identification have their owner obvious strongpoint in universality and digitalization. In the near future, the two techniques are promising to be the main trend for identifying traditional Chinese medicinal materials. The identification techniques based on microscopy, liquid chromatography, PCR, biological effects and DNA chip will be indispensable supplements. However, the bionic identification technology is just placed in the developing stage at present.

  11. Realising the technological promise of smartphones in addiction research and treatment: An ethical review.

    PubMed

    Capon, Hannah; Hall, Wayne; Fry, Craig; Carter, Adrian

    2016-10-01

    Smartphone technologies and mHealth applications (or apps) promise unprecedented scope for data collection, treatment intervention, and relapse prevention when used in the field of substance abuse and addiction. This potential also raises new ethical challenges that researchers, clinicians, and software developers must address. This paper aims to identify ethical issues in the current uses of smartphones in addiction research and treatment. A search of three databases (PubMed, Web of Science and PsycInfo) identified 33 studies involving smartphones or mHealth applications for use in the research and treatment of substance abuse and addiction. A content analysis was conducted to identify how smartphones are being used in these fields and to highlight the ethical issues raised by these studies. Smartphones are being used to collect large amounts of sensitive information, including personal information, geo-location, physiological activity, self-reports of mood and cravings, and the consumption of illicit drugs, alcohol and nicotine. Given that detailed information is being collected about potentially illegal behaviour, we identified the following ethical considerations: protecting user privacy, maximising equity in access, ensuring informed consent, providing participants with adequate clinical resources, communicating clinically relevant results to individuals, and the urgent need to demonstrate evidence of safety and efficacy of the technologies. mHealth technology offers the possibility to collect large amounts of valuable personal information that may enhance research and treatment of substance abuse and addiction. To realise this potential researchers, clinicians and app-developers must address these ethical concerns to maximise the benefits and minimise risks of harm to users. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. The Promise of Information and Communication Technology in Healthcare: Extracting Value From the Chaos.

    PubMed

    Mamlin, Burke W; Tierney, William M

    2016-01-01

    Healthcare is an information business with expanding use of information and communication technologies (ICTs). Current ICT tools are immature, but a brighter future looms. We examine 7 areas of ICT in healthcare: electronic health records (EHRs), health information exchange (HIE), patient portals, telemedicine, social media, mobile devices and wearable sensors and monitors, and privacy and security. In each of these areas, we examine the current status and future promise, highlighting how each might reach its promise. Steps to better EHRs include a universal programming interface, universal patient identifiers, improved documentation and improved data analysis. HIEs require federal subsidies for sustainability and support from EHR vendors, targeting seamless sharing of EHR data. Patient portals must bring patients into the EHR with better design and training, greater provider engagement and leveraging HIEs. Telemedicine needs sustainable payment models, clear rules of engagement, quality measures and monitoring. Social media needs consensus on rules of engagement for providers, better data mining tools and approaches to counter disinformation. Mobile and wearable devices benefit from a universal programming interface, improved infrastructure, more rigorous research and integration with EHRs and HIEs. Laws for privacy and security need updating to match current technologies, and data stewards should share information on breaches and standardize best practices. ICT tools are evolving quickly in healthcare and require a rational and well-funded national agenda for development, use and assessment. Copyright © 2016 Southern Society for Clinical Investigation. Published by Elsevier Inc. All rights reserved.

  13. Evaluation of technology to identify and assess overweight children and adolescents.

    PubMed

    Gance-Cleveland, Bonnie; Gilbert, Lynn H; Kopanos, Taynin; Gilbert, Kevin C

    2010-01-01

    The current obesity epidemic has produced a generation of children that may be the first to have a life expectancy shorter than their parents. To address the obesity epidemic, experts have published recommendations for providers. Research suggests the publication of guidelines may not change provider behavior. This study evaluates computer assistance for implementing obesity guidelines in school-based health centers. Significant improvements in identification and assessment of obesity in children with technology support were noted. Computer decision support shows promise for promoting the implementation of current recommendations by supporting providers in identifying, assessing, and providing tailored recommendations for children at risk of obesity.

  14. The Promises and Pitfalls of Digital Technology in Its Application to Alcohol Treatment

    PubMed Central

    Muench, Frederick

    2014-01-01

    Individuals seeking to change their alcohol use form a heterogeneous group with varied treatment goals—including moderation and abstinence—that therefore requires flexible treatment options. The availability of alcohol in the United States, and the pervasive social pressure to drink, warrant treatments that support individuals outside the treatment environment and that foster coping and self-regulation in the face of these demands. Emerging digital technologies show promise for helping both to hone therapies to clients’ individual needs and to support clients in settings beyond the clinic. In the broader health care arena, digital health technologies (DHTs) are transforming how health professionals assess, prevent, and treat both physical and mental health problems. DHTs include assessments and interventions delivered via computer, Internet, mobile phone, and wireless or wearable device technologies. The emerging literature examining within-treatment and mobile DHTs highlights an opportunity to create personalized alcohol treatments for every person seeking care. Despite the promises DHTs may hold, however, there still are many potential risks to using them and a number of challenges regarding how to integrate them into treatment successfully. This article will review the current and potential advantages of DHTs in alcohol treatment and the technological, personal, organizational, and systemic limitations of integrating various technology-based assessment and intervention programs into care. PMID:26259008

  15. [Promising technologies of packed red blood cells production and storage].

    PubMed

    Maksimov, A G; Golota, A S; Krassiĭ, A B

    2013-10-01

    The current article is dedicated to promising technologies of packed red blood cells production and storage. The following new technical approaches are presented: (1) erythrocytes storage in strict anaerobic argon-hydrogen environment, (2) lyophilization of erythrocyte suspension by its atomization in nitrogen gas, (3) lyophilization of erythrocytes by directional freezing under the influence of radio frequency radiation, (4) automated pharming of antigen free packed red blood cells from progenitor cell directly at the battlefield.

  16. CDC's DELTA FOCUS Program: Identifying Promising Primary Prevention Strategies for Intimate Partner Violence.

    PubMed

    Armstead, Theresa L; Rambo, Kirsten; Kearns, Megan; Jones, Kathryn M; Dills, Jenny; Brown, Pamela

    2017-01-01

    According to 2011 data, nearly one in four women and one in seven men in the United States experience severe physical violence by an intimate partner, creating a public health burden requiring population-level solutions. To prevent intimate partner violence (IPV) before it occurs, the CDC developed Domestic Violence Prevention Enhancements and Leadership Through Alliances, Focusing on Outcomes for Communities United with States to identify promising community- and societal-level prevention strategies to prevent IPV. The program funds 10 state domestic violence coalitions for 5 years to implement and evaluate programs and policies to prevent IPV by influencing the environments and conditions in which people live, work, and play. The program evaluation goals are to promote IPV prevention by identifying promising prevention strategies and describing those strategies using case studies, thereby creating a foundation for building practice-based evidence with a health equity approach.

  17. Identifying Advanced Technologies for Education's Future.

    ERIC Educational Resources Information Center

    Moore, Gwendolyn B.; Yin, Robert K.

    A study to determine how three advanced technologies might be applied to the needs of special education students helped inspire the development of a new method for identifying such applications. This new method, named the "Hybrid Approach," combines features of the two traditional methods: technology-push and demand-pull. Technology-push involves…

  18. A Pedagogical Framework for Technology Integration in ESL Classrooms: The Promises and Challenges of Integration

    ERIC Educational Resources Information Center

    Yang, Sha; Walker, Victoria

    2015-01-01

    Technologies have the potential to support language teaching and learning, but English as a Second Language (ESL) teachers in the United States (U.S.) either sparingly use technologies for instruction or use them at low level. Although previous research has indicated some promises and challenges faced by U.S. ESL teachers with integrating…

  19. Scientometric methods for identifying emerging technologies

    DOEpatents

    Abercrombie, Robert K; Schlicher, Bob G; Sheldon, Frederick T

    2015-11-03

    Provided is a method of generating a scientometric model that tracks the emergence of an identified technology from initial discovery (via original scientific and conference literature), through critical discoveries (via original scientific, conference literature and patents), transitioning through Technology Readiness Levels (TRLs) and ultimately on to commercial application. During the period of innovation and technology transfer, the impact of scholarly works, patents and on-line web news sources are identified. As trends develop, currency of citations, collaboration indicators, and on-line news patterns are identified. The combinations of four distinct and separate searchable on-line networked sources (i.e., scholarly publications and citation, worldwide patents, news archives, and on-line mapping networks) are assembled to become one collective network (a dataset for analysis of relations). This established network becomes the basis from which to quickly analyze the temporal flow of activity (searchable events) for the example subject domain.

  20. The role of surgeons in identifying emerging technologies for health technology assessment.

    PubMed

    Stafinski, Tania; Topfer, Leigh-Ann; Zakariasen, Ken; Menon, Devidas

    2010-04-01

    Health technology assessment (HTA) is a tool intended to help policy-makers decide which technologies to fund. However, given the proliferation of new technologies, it is not possible to undertake an HTA of each one before it becomes funded. Consequently, "horizon-scanning" processes have been developed to identify emerging technologies that are likely to have a substantial impact on clinical practice. Although the importance of physicians in the adoption of new technologies is well recognized, their role in horizon scanning in Canada has been limited. The purpose of this project was to pilot an approach to engage physicians, specifically surgeons, in provincial horizon-scanning activities. We invited 18 surgeons from Alberta's 2 medical schools to a horizon-scanning workshop to solicit their views on emerging technologies expected to impact surgical practice within the next 5 years and/or the importance of different attributes or characteristics of new technologies. Surgeons, regardless of specialty, identified developments designed to enhance existing minimally invasive surgical techniques, such as endoscopic, robotic and image-guided surgery. Several nonsurgical areas, including molecular genetics and nano technology, were also identified. Of the 13 technology attributes discussed, safety or risk, effectiveness and feasibility were rated as most important. Lastly, participating surgeons expressed an interest in becoming further involved in local HTA initiatives. Surgeons, as adopters and users of health technologies, represent an important and accessible information source for identifying emerging technologies for HTA. A more formal, ongoing relationship between the government, HTA and surgeons may help to optimize the use of HTA resources.

  1. The promise and the reality: a mental health workforce perspective on technology-enhanced youth mental health service delivery.

    PubMed

    Orlowski, Simone; Lawn, Sharon; Matthews, Ben; Venning, Anthony; Wyld, Kaisha; Jones, Gabrielle; Winsall, Megan; Antezana, Gaston; Schrader, Geoffrey; Bidargaddi, Niranjan

    2016-10-10

    Digital technologies show promise for reversing poor engagement of youth (16-24 years) with mental health services. In particular, mobile and internet based applications with communication capabilities can augment face-to-face mental health service provision. The literature in this field, however, fails to adequately capture the perspectives of the youth mental health workforce regarding utility and acceptability of technology for this purpose. This paper describes results of in-depth qualitative data drawn from various stakeholders involved in provision of youth mental health services in one Australian rural region. Data were obtained using focus groups and semi-structured interviews with regional youth mental health clinicians, youth workers and support/management staff (n = 4 focus groups; n = 8 interviews) and analysed via inductive thematic analysis. Results question the acceptability of technology to engage clients within youth mental health services. Six main themes were identified: young people in a digital age, personal connection, power and vulnerability, professional identity, individual factors and organisational legitimacy. These findings deepen the understanding of risks and challenges faced when adopting new technologies in mental healthcare. Recommendations for technology design and implementation in mental health services are made.

  2. The role of surgeons in identifying emerging technologies for health technology assessment

    PubMed Central

    Stafinski, Tania; Topfer, Leigh-Ann; Zakariasen, Ken; Menon, Devidas

    2010-01-01

    Background Health technology assessment (HTA) is a tool intended to help policy-makers decide which technologies to fund. However, given the proliferation of new technologies, it is not possible to undertake an HTA of each one before it becomes funded. Consequently, “horizon-scanning” processes have been developed to identify emerging technologies that are likely to have a substantial impact on clinical practice. Although the importance of physicians in the adoption of new technologies is well recognized, their role in horizon scanning in Canada has been limited. The purpose of this project was to pilot an approach to engage physicians, specifically surgeons, in provincial horizon-scanning activities. Methods We invited 18 surgeons from Alberta’s 2 medical schools to a horizon-scanning workshop to solicit their views on emerging technologies expected to impact surgical practice within the next 5 years and/or the importance of different attributes or characteristics of new technologies. Results Surgeons, regardless of specialty, identified developments designed to enhance existing minimally invasive surgical techniques, such as endoscopic, robotic and image-guided surgery. Several nonsurgical areas, including molecular genetics and nanotechnology, were also identified. Of the 13 technology attributes discussed, safety or risk, effectiveness and feasibility were rated as most important. Lastly, participating surgeons expressed an interest in becoming further involved in local HTA initiatives. Conclusion Surgeons, as adopters and users of health technologies, represent an important and accessible information source for identifying emerging technologies for HTA. A more formal, ongoing relationship between the government, HTA and surgeons may help to optimize the use of HTA resources. PMID:20334740

  3. Amyloid Beta and Tau as Alzheimer's Disease Blood Biomarkers: Promise From New Technologies.

    PubMed

    Lue, Lih-Fen; Guerra, Andre; Walker, Douglas G

    2017-07-01

    The utility of the levels of amyloid beta (Aβ) peptide and tau in blood for diagnosis, drug development, and assessment of clinical trials for Alzheimer's disease (AD) has not been established. The lack of availability of ultra-sensitive assays is one critical issue that has impeded progress. The levels of Aβ species and tau in plasma and serum are much lower than levels in cerebrospinal fluid. Furthermore, plasma or serum contain high levels of assay-interfering factors, resulting in difficulties in the commonly used singulex or multiplex ELISA platforms. In this review, we focus on two modern immune-complex-based technologies that show promise to advance this field. These innovative technologies are immunomagnetic reduction technology and single molecule array technology. We describe the technologies and discuss the published studies using these technologies. Currently, the potential of utilizing these technologies to advance Aβ and tau as blood-based biomarkers for AD requires further validation using already collected large sets of samples, as well as new cohorts and population-based longitudinal studies.

  4. Impedance-based cellular assay technologies: recent advances, future promise.

    PubMed

    McGuinness, Ryan

    2007-10-01

    Cell-based assays are continuing to grow in importance in the drug discovery workflow. Their early introduction holds the promise of limiting attrition in the later, more costly phases of the process. This article reviews recent advances in the development of impedance technologies for label-free cell-based assays. These systems are capable of monitoring endogenous receptor activation, and thus generate more physiologically relevant measures of pharmacological endpoints. Primary cells can be investigated as well, thus producing disease relevant information. Label-free assays significantly decrease assay development efforts and avoid many complications inherent in recombinant readout systems. Impedance-based systems have great potential to advance the utility of cell-based assays as they are applied to drug discovery and pharmacology.

  5. Utility, Limitations, and Promise of Proteomics in Animal Science

    USDA-ARS?s Scientific Manuscript database

    Proteomics experiments have the ability to simultaneously identify and quantify thousands of proteins in one experiment. The use of this technology in veterinary/animal science is still in its infancy, yet it holds significant promise as a method for advancing veterinary/animal science research. E...

  6. Flotation: A promising microalgae harvesting and dewatering technology for biofuels production.

    PubMed

    Ndikubwimana, Theoneste; Chang, Jingyu; Xiao, Zongyuan; Shao, Wenyao; Zeng, Xianhai; Ng, I-Son; Lu, Yinghua

    2016-03-01

    Microalgal biomass as renewable energy source is believed to be of great potential for reliable and sustainable biofuels production. However, microalgal biomass production is pinned by harvesting and dewatering stage thus hindering the developing and growing microalgae biotechnology industries. Flotation technology applied in mineral industry could be potentially applied in microalgae harvesting and dewatering, however substantial knowledge on different flotation units is essential. This paper presents an overview on different flotation units as promising cost-effective technologies for microalgae harvesting thus bestowing for further research in development and commercialization of microalgae based biofuels. Dispersed air flotation was found to be less energy consuming. Moreover, Jameson cell flotation and dispersed ozone flotation are believed to be energy efficient microalgae flotation approaches. Microalgae harvesting and dewatering by flotation is still at embryonic stage, therefore extended studies with the focus on life cycle assessment, sustainability of the flotation unit, optimization of the operating parameters using different algal species is imperative. Though there are a number of challenges in microalgae harvesting and dewatering, with well designed and developed cultivation, harvesting/dewatering, extraction and conversion technologies, progressively, microalgae technology will be of great potential for biological carbon sequestration, biofuels and biochemicals production. Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. The Utility, Limitations, and Promise of Proteomics in Animal Science

    USDA-ARS?s Scientific Manuscript database

    Proteomics experiments have the ability to simultaneously identify and quantify potentially thousands of proteins in one experiment. The use of this technology in animal science is still in its infancy, yet it holds significant promise as a method for advancing animal science research. Examples of...

  8. Technology and Interactive Multimedia. Identifying Emerging Issues and Trends in Technology for Special Education.

    ERIC Educational Resources Information Center

    Ashton, Ray

    As part of a 3-year study to identify emerging issues and trends in technology for special education, this paper addresses the role of interactive multimedia, especially the digital, optical compact disc technologies, in providing instructional services to special education students. An overview identifies technological and economic trends,…

  9. Digital technology in respiratory diseases: Promises, (no) panacea and time for a new paradigm.

    PubMed

    Pinnock, Hilary; McKinstry, Brian

    2016-05-01

    In a world where digital technology has revolutionized the way we work, shop and manage our finances it is unsurprising that digital systems are suggested as potential solutions to delivering clinically and cost-effective care for an aging population with one or more long-term conditions. However, recent evidence suggesting that telehealth may not be quite the panacea that was promised, has led to discussions on the mechanisms and role of digital technology in respiratory care. Implementation in rural and remote settings offers significant benefits in terms of convenient access to care, but is contingent on technical and organizational infrastructure. Telemonitoring systems rely on algorithms to detect deterioration and trigger alerts; machine learning may enable telemonitoring of the future to develop personalized systems that are sensitive to clinical status whilst reducing false alerts. By providing access to information, offering convenient and flexible modes of communication and enabling the transfer of monitoring data to support professional assessment, telehealth can support self-management. At present, all too often, expensive 'off the shelf' systems are purchased and given to clinicians to use. It is time for the paradigm to shift. As clinicians we should identify the specific challenges we face in delivering care, and expect flexible systems that can be customized to individual patients' requirements and adapted to our diverse healthcare contexts. © The Author(s) 2016.

  10. Promising Practices in Higher Education: Art Education and Human Rights Using Information, Communication Technologies (ICT)

    ERIC Educational Resources Information Center

    Black, Joanna; Cap, Orest

    2014-01-01

    Promising pedagogical practices is described in relation to incorporating ICT (Information, Communication and Technologies) with the study of Human Rights issues in Visual Arts Education for teacher candidates. As part of a course, "Senior Years Art," students at the Faculty of Education, University of Manitoba during 2013-2014…

  11. Low-temperature deposition manufacturing: A novel and promising rapid prototyping technology for the fabrication of tissue-engineered scaffold.

    PubMed

    Liu, Wei; Wang, Daming; Huang, Jianghong; Wei, You; Xiong, Jianyi; Zhu, Weimin; Duan, Li; Chen, Jielin; Sun, Rong; Wang, Daping

    2017-01-01

    Developed in recent years, low-temperature deposition manufacturing (LDM) represents one of the most promising rapid prototyping technologies. It is not only based on rapid deposition manufacturing process but also combined with phase separation process. Besides the controlled macropore size, tissue-engineered scaffold fabricated by LDM has inter-connected micropores in the deposited lines. More importantly, it is a green manufacturing process that involves non-heating liquefying of materials. It has been employed to fabricate tissue-engineered scaffolds for bone, cartilage, blood vessel and nerve tissue regenerations. It is a promising technology in the fabrication of tissue-engineered scaffold similar to ideal scaffold and the design of complex organs. In the current paper, this novel LDM technology is introduced, and its control parameters, biomedical applications and challenges are included and discussed as well. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Technology Implementation in Education--Identifying Barriers to Fidelity

    ERIC Educational Resources Information Center

    Monroe, Arla K.; Dennis, William J.; Johnson, Daniel L.

    2012-01-01

    This report describes a problem-based learning project focused on determining the barriers to the implementation of technological innovations. that properly executed technology implementation is an instructional variable related to student achievement; yet, school district leaders are faced with the problem of recognizing and identifying the…

  13. Computers and Curriculum--Promises and Problems.

    ERIC Educational Resources Information Center

    Caldwell, Robert M.

    The educational problems of the United States have reached critical proportions, particularly if the nation is to maintain leadership in high technology industries. This document explores the promise technology offers for improving instruction and broadening alternatives for instructional delivery. The author considers how technologically assisted…

  14. Integrated intravascular ultrasound and optical coherence tomography technology: a promising tool to identify vulnerable plaques [INVITED PAPER

    PubMed Central

    Li, Jiawen; Chen, Zhongping

    2017-01-01

    Heart attack is mainly caused by the rupture of a vulnerable plaque. IVUS-OCT is a novel medical imaging modality that provides opportunities for accurate assessment of vulnerable plaques in vivo in patients. IVUS provides deep penetration to image the whole necrotic core while OCT enables accurate measurement of the fibrous cap of a plaque owing to its high resolution. In this paper, the authors describe the fundamentals, the technical designs and the applications of IVUS-OCT technology. Results from cadaver specimens are summarized, which indicated the complementary nature of OCT and IVUS for assessment of vulnerable plaques, plaque composition, and stent-tissue interactions. Furthermore, previously reported in vivo animal experiments are reviewed to assess the clinical adaptability of IVUS-OCT. Future directions for this technology are also discussed in this review. PMID:28966987

  15. Identifying Facets of Technology Satisfaction: Measure Development and Application

    ERIC Educational Resources Information Center

    Njoroge, Joyce; Norman, Andrew; Reed, Diana; Suh, Inchul

    2012-01-01

    As institutions of higher learning, universities must devote significant resources in developing intellectual capital in the use of educational technology to sustain their viability. To better understand satisfaction in technology used in classrooms, a psychometric instrument was developed to identify and measure the specific factors of…

  16. Genetic technology: Promises and problems

    NASA Technical Reports Server (NTRS)

    Frankel, M. S.

    1975-01-01

    Issues concerning the use of genetic technology are discussed. Some areas discussed include treating genetic disease, prenatal diagnosis and selective abortion, screening for genetic disease, and genetic counseling. Policy issues stemming from these capabilities are considered.

  17. The Risky Promises and Promising Risks of New Information Technologies for Education.

    ERIC Educational Resources Information Center

    Burbules, Nicholas C.; Callister, Thomas A., Jr.

    1999-01-01

    Attempts to come to terms with the role of information technology in education. Proposes a post-technocratic view of information technology that recognizes the multiplicity of its effects, the indeterminacy and inseparability of consequences, and the difficulty of isolating "good" and "bad" outcomes. (Author/WRM)

  18. Technology's Potential, Promise for Enhancing Student Learning

    ERIC Educational Resources Information Center

    Golden, Michael

    2004-01-01

    Technology is a tool that has the potential to empower educational leaders at all levels--whether they are superintendents, principals, teachers, board members or state officials--as well as to redefine what education means in the 21st century. Technology provides more accurate information and advanced communication capabilities. Technology can be…

  19. The Promise of Microbial Technology.

    ERIC Educational Resources Information Center

    El Nawawy, Amin S.

    1982-01-01

    Prospects for microbial technology are discussed including: (1) possible transfer of nitrogen-fixing ability directly from bacteria to plant; (2) increasing food needs met through single-cell proteins and fermentation; (3) microbial production of antibiotics; and (4) increased biogas production. (Author/JN)

  20. A strategy for advancing tilt-rotor technology

    NASA Technical Reports Server (NTRS)

    Morlok, Edward K.; Schoendorfer, David L.

    1985-01-01

    Tilt-rotor technology has many features which make it a very promising development in aviation which might have application to a wide variety of transportation and logistics situations. However, aside from military applications and rather specialized industrial applications, little is known regarding the potential of tilt-rotor for commercial transportation and hence it is difficult to plan a development program which would gain support and be likely to produce a stream of significant benefits. The purpose is to attempt to provide some of this information in a manner that would be useful for preparing a strategy for development of tilt-rotor aircraft technology. Specifically, the objectives were: to identify promising paths of development and deployment of tilt-rotor aircraft technology in the air transportation system considering both benefits and disbenefits, and to identify any particular groups that are likely to benefit significantly and propose plans for gaining their support of research and development of this technology. Potential advantages of the tilt-rotor technology in the context of air transportation as a door-to-door system were identified, and then promising paths of development of such tilt-rotor systems were analyzed. These then lead to recommendations for specific studies, information dissemination and development of awareness of the tilt-rotor among specific transport-related groups.

  1. Awareness of technology-induced errors and processes for identifying and preventing such errors.

    PubMed

    Bellwood, Paule; Borycki, Elizabeth M; Kushniruk, Andre W

    2015-01-01

    There is a need to determine if organizations working with health information technology are aware of technology-induced errors and how they are addressing and preventing them. The purpose of this study was to: a) determine the degree of technology-induced error awareness in various Canadian healthcare organizations, and b) identify those processes and procedures that are currently in place to help address, manage, and prevent technology-induced errors. We identified a lack of technology-induced error awareness among participants. Participants identified there was a lack of well-defined procedures in place for reporting technology-induced errors, addressing them when they arise, and preventing them.

  2. Application of advanced technologies to derivatives of current small transport aircraft

    NASA Technical Reports Server (NTRS)

    Renze, P. P.; Terry, J. E.

    1981-01-01

    Mission requirements of the derivative design were the same as the baseline to readily identify the advanced technology benefits achieved. Advanced technologies investigated were in the areas of propulsion, structures and aerodynamics and a direct operating cost benefit analysis conducted to identify the most promising. Engine improvements appear most promising and combined with propeller, airfoil, surface coating and composite advanced technologies give a 21-25 percent DOC savings. A 17 percent higher acquisition cost is offset by a 34 percent savings in fuel used.

  3. Identifying technology innovations for marginalized smallholders-A conceptual approach.

    PubMed

    Malek, Mohammad Abdul; Gatzweiler, Franz W; Von Braun, Joachim

    2017-05-01

    This paper adds a contribution in the existing literature in terms of theoretical and conceptual background for the identification of idle potentials of marginal rural areas and people by means of technological and institutional innovations. The approach follows ex-ante assessment for identifying suitable technology and institutional innovations for marginalized smallholders in marginal areas-divided into three main parts (mapping, surveying and evaluating) and several steps. Finally, it contributes to the inclusion of marginalized smallholders by an improved way of understanding the interactions between technology needs, farming systems, ecological resources and poverty characteristics in the different segments of the poor, and to link these insights with productivity enhancing technologies.

  4. Resourcefulness training intervention: a promising approach to improve mental health of mothers with technology-dependent children.

    PubMed

    Toly, Valerie Boebel; Musil, Carol M; Zauszniewski, Jaclene A

    2014-02-01

    The population of children dependent on medical technology such as mechanical ventilation, feeding tubes, and supplemental oxygen continues to grow in the United States. These children are frequently cared for by their mothers at home following hospital discharge. Research indicates that these mothers are at high risk for negative mental health outcomes that affect both caregiver and care recipient. The purpose of this randomized controlled pilot trial was to determine the feasibility, acceptability, and efficacy of resourcefulness training (RT), a cognitive-behavioral intervention, among mothers of technology-dependent children. RT was found to be a feasible and acceptable intervention with this population during the 6 week study. The effect size in this pilot study demonstrates initial efficacy and indicates areas for strengthening the intervention protocol. RT is a promising intervention that can be employed by pediatric nurses to assist mothers in the home management of technology-dependent children. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. The Use of Technology in Identifying Hospital Malnutrition: Scoping Review.

    PubMed

    Trtovac, Dino; Lee, Joon

    2018-01-19

    Malnutrition is a condition most commonly arising from the inadequate consumption of nutrients necessary to maintain physiological health and is associated with the development of cardiovascular disease, osteoporosis, and sarcopenia. Malnutrition occurring in the hospital setting is caused by insufficient monitoring, identification, and assessment efforts. Furthermore, the ability of health care workers to identify and recognize malnourished patients is suboptimal. Therefore, interventions focusing on the identification and treatment of malnutrition are valuable, as they reduce the risks and rates of malnutrition within hospitals. Technology may be a particularly useful ally in identifying malnutrition due to scalability, timeliness, and effectiveness. In an effort to explore the issue, this scoping review synthesized the availability of technological tools to detect and identify hospital malnutrition. Our objective was to conduct a scoping review of the different forms of technology used in addressing malnutrition among adults admitted to hospital to (1) identify the extent of the published literature on this topic, (2) describe key findings, and (3) identify outcomes. We designed and implemented a search strategy in 3 databases (PubMed, Scopus, and CINAHL). We completed a descriptive numerical summary and analyzed study characteristics. One reviewer independently extracted data from the databases. We retrieved and reviewed a total of 21 articles. We categorized articles by the computerized tool or app type: malnutrition assessment (n=15), food intake monitoring (n=5), or both (n=1). Within those categories, we subcategorized the different technologies as either hardware (n=4), software (n=13), or both (n=4). An additional subcategory under software was cloud-based apps (n=1). Malnutrition in the acute hospital setting was largely an unrecognized problem, owing to insufficient monitoring, identification, and initial assessments of identifying both patients who are

  6. Fulfilling a Promise: Standards for Technological Literacy.

    ERIC Educational Resources Information Center

    Bybee, Rodger W.

    2003-01-01

    Discusses the place of standards in U.S. education, the development of the Standards for Technological Literacy, and the recent publication of "Advancing Excellence in Technological Literacy: Student Assessment, Professional Development, and Program Standards." (Contains 21 references.) (SK)

  7. Looking Back and Looking Forward: Reprising the Promise and Predicting the Future of Formation Flying and Spaceborne GPS Navigation Systems

    NASA Technical Reports Server (NTRS)

    Bauer, Frank H.; Dennehy, Neil

    2015-01-01

    A retrospective consideration of two 15-year old Guidance, Navigation and Control (GN&C) technology 'vision' predictions will be the focus of this paper. A look back analysis and critique of these late 1990s technology roadmaps out-lining the future vision, for two then nascent, but rapidly emerging, GN&C technologies will be performed. Specifically, these two GN&C technologies were: 1) multi-spacecraft formation flying and 2) the spaceborne use and exploitation of global positioning system (GPS) signals to enable formation flying. This paper reprises the promise of formation flying and spaceborne GPS as depicted in the cited 1999 and 1998 papers. It will discuss what happened to cause that promise to be mostly unfulfilled and the reasons why the envisioned formation flying dream has yet to become a reality. The recent technology trends over the past few years will then be identified and a renewed government interest in spacecraft formation flying/cluster flight will be highlighted. The authors will conclude with a reality-tempered perspective, 15 years after the initial technology roadmaps were published, predicting a promising future of spacecraft formation flying technology development over the next decade.

  8. The power and promise of applying genomics to honey bee health.

    PubMed

    Grozinger, Christina M; Robinson, Gene E

    2015-08-01

    New genomic tools and resources are now being used to both understand honey bee health and develop tools to better manage it. Here, we describe the use of genomic approaches to identify and characterize bee parasites and pathogens, examine interactions among these parasites and pathogens, between them and their bee hosts, and to identify genetic markers for improved breeding of more resilient bee stocks. We also discuss several new genomic techniques that can be used to more efficiently study, monitor and improve bee health. In the case of using RNAi-based technologies to mitigate diseases in bee populations, we highlight advantages, disadvantages and strategies to reduce risk. The increased use of genomic analytical tools and manipulative technologies has already led to significant advances, and holds great promise for improvements in the health of honey bees and other critical pollinator species.

  9. The power and promise of applying genomics to honey bee health

    PubMed Central

    Robinson, Gene E.

    2015-01-01

    New genomic tools and resources are now being used to both understand honey bee health and develop tools to better manage it. Here, we describe the use of genomic approaches to identify and characterize bee parasites and pathogens, examine interactions among these parasites and pathogens, between them and their bee hosts, and to identify genetic markers for improved breeding of more resilient bee stocks. We also discuss several new genomic techniques that can be used to more efficiently study, monitor and improve bee health. In the case of using RNAi-based technologies to mitigate diseases in bee populations, we highlight advantages, disadvantages and strategies to reduce risk. The increased use of genomic analytical tools and manipulative technologies has already led to significant advances, and holds great promise for improvements in the health of honey bees and other critical pollinator species. PMID:26273565

  10. NLEAP/GIS approach for identifying and mitigating regional nitrate-nitrogen leaching

    USGS Publications Warehouse

    Shaffer, M.J.; Hall, M.D.; Wylie, B.K.; Wagner, D.G.; Corwin, D.L.; Loague, K.

    1996-01-01

    Improved simulation-based methodology is needed to help identify broad geographical areas where potential NO3-N leaching may be occurring from agriculture and suggest management alternatives that minimize the problem. The Nitrate Leaching and Economic Analysis Package (NLEAP) model was applied to estimate regional NO3-N leaching in eastern Colorado. Results show that a combined NLEAP/GIS technology can be used to identify potential NO3-N hot spots in shallow alluvial aquifers under irrigated agriculture. The NLEAP NO3-N Leached (NL) index provided the most promising single index followed by NO3-N Available for Leaching (NAL). The same combined technology also shows promise in identifying Best Management Practice (BMP) methods that help minimize NO3-N leaching in vulnerable areas. Future plans call for linkage of the NLEAP/GIS procedures with groundwater modeling to establish a mechanistic analysis of agriculture-aquifer interactions at a regional scale.

  11. A Checklist for Identifying Funding Sources for Assistive Technology.

    ERIC Educational Resources Information Center

    Menlove, Martell

    1996-01-01

    This article offers a systematically organized series of questions to identify funding sources for assistive technology for students with disabilities. A decision tree links the questions with funding sources. (DB)

  12. Impact and promise of NASA aeropropulsion technology

    NASA Technical Reports Server (NTRS)

    Saunders, Neal T.; Bowditch, David N.

    1990-01-01

    The aeropropulsion industry in the U.S. has established an enviable record of leading the world in aeropropulsion for commercial and military aircraft. NASA's aeropropulsion program (primarily conducted through the Lewis Research Center) has significantly contributed to that success through research and technology advances and technology demonstration. Some past NASA contributions to engines in current aircraft are reviewed, and technologies emerging from current research programs for the aircraft of the 1990's are described. Finally, current program thrusts toward improving propulsion systems in the 2000's for subsonic commercial aircraft and higher speed aircraft such as the High-Speed Civil Transport and the National Aerospace Plane are discussed.

  13. Distinct Patterns of Cognitive Conflict Dynamics in Promise Keepers and Promise Breakers.

    PubMed

    Calluso, Cinzia; Saulin, Anne; Baumgartner, Thomas; Knoch, Daria

    2018-01-01

    On a daily basis, we see how different people can be in keeping or breaking a given promise. However, we know very little about the cognitive conflict dynamics that underlie the decision to keep or break a promise and whether this is shaped by inter-individual variability. In order to fill this gap, we applied an ecologically valid promise decision task with real monetary consequences for all involved interaction partners and used mouse tracking to identify the dynamic, on-line cognitive processes that underlie the decision to keep or break a promise. Our findings revealed that on average, the process of breaking a promise is associated with largely curved mouse trajectories, while the process of keeping a promise was not, indicating that breaking a promise is associated with a larger conflict. Interestingly, however, this conflict pattern was strongly shaped by individual differences. Individuals who always kept their promises did not show any signs of conflict (i.e., straight mouse trajectories), indicating that they were not tempted by the monetary benefits associated with breaking the promise. In contrast, individuals who did not always keep their promise exhibited a large conflict (i.e., curved mouse trajectories), irrespective of whether they broke or kept their promise. A possible interpretation of these findings is that these individuals were always tempted by the unchosen decision option - the desire to act in a fair manner when breaking the promise and the monetary benefits when keeping the promise. This study provides the first piece of evidence that there are substantial inter-individual differences in cognitive conflict dynamics that underlie the decision to keep or break promises and that mouse tracking is able to illuminate important insights into individual differences in complex human's decision processes.

  14. Impact and promise of NASA aeropropulsion technology

    NASA Technical Reports Server (NTRS)

    Saunders, Neal T.; Bowditch, David N.

    1987-01-01

    The aeropropulsion industry in the United States has established an enviable record of leading the world in aeropropulsion for commercial and military aircraft. The NASA aeropropulsion propulsion program (primarily conducted through the Lewis Research Center) has significantly contributed to that success through research and technology advances and technology demonstrations such as the Refan, Engine Component Improvement, and the Energy Efficient Engine Programs. Some past NASA contributions to engines in current aircraft are reviewed, and technologies emerging from current research programs for the aircraft of the 1990's are described. Finally, current program thrusts toward improving propulsion systems in the 2000's for subsonic commercial aircraft and higher speed aircraft such as the High-Speed Civil Transport and the National Aerospace Plane (NASP) are discussed.

  15. Instructional Technology and Reading: Progress, Problems, and Promise.

    ERIC Educational Resources Information Center

    Smith, Nila Banton

    As the invention of the wheel played a large role in the technological advancement of transportation, so many new teaching devices have played an important role in the technological advancement of reading instruction. Though the spread of technology was initially slow, it now offers many instructional aids (e.g., tapes, records, television,…

  16. Melter Technologies Assessment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Perez, J.M. Jr.; Schumacher, R.F.; Forsberg, C.W.

    1996-05-01

    The problem of controlling and disposing of surplus fissile material, in particular plutonium, is being addressed by the US Department of Energy (DOE). Immobilization of plutonium by vitrification has been identified as a promising solution. The Melter Evaluation Activity of DOE`s Plutonium Immobilization Task is responsible for evaluating and selecting the preferred melter technologies for vitrification for each of three immobilization options: Greenfield Facility, Adjunct Melter Facility, and Can-In-Canister. A significant number of melter technologies are available for evaluation as a result of vitrification research and development throughout the international communities for over 20 years. This paper describes an evaluationmore » process which will establish the specific requirements of performance against which candidate melter technologies can be carefully evaluated. Melter technologies that have been identified are also described.« less

  17. Consumer-identified barriers and strategies for optimizing technology use in the workplace.

    PubMed

    De Jonge, Desleigh M; Rodger, Sylvia A

    2006-01-01

    This article explores the experiences of 26 assistive technology (AT) users having a range of physical impairments as they optimized their use of technology in the workplace. A qualitative research design was employed using in-depth, open-ended interviews and observations of AT users in the workplace. Participants identified many factors that limited their use of technology such as discomfort and pain, limited knowledge of the technology's features, and the complexity of the technology. The amount of time required for training, limited work time available for mastery, cost of training and limitations of the training provided, resulted in an over-reliance on trial and error and informal support networks and a sense of isolation. AT users enhanced their use of technology by addressing the ergonomics of the workstation and customizing the technology to address individual needs and strategies. Other key strategies included tailored training and learning support as well as opportunities to practice using the technology and explore its features away from work demands. This research identified structures important for effective AT use in the workplace which need to be put in place to ensure that AT users are able to master and optimize their use of technology.

  18. Three-dimensional imaging technology offers promise in medicine.

    PubMed

    Karako, Kenji; Wu, Qiong; Gao, Jianjun

    2014-04-01

    Medical imaging plays an increasingly important role in the diagnosis and treatment of disease. Currently, medical equipment mainly has two-dimensional (2D) imaging systems. Although this conventional imaging largely satisfies clinical requirements, it cannot depict pathologic changes in 3 dimensions. The development of three-dimensional (3D) imaging technology has encouraged advances in medical imaging. Three-dimensional imaging technology offers doctors much more information on a pathology than 2D imaging, thus significantly improving diagnostic capability and the quality of treatment. Moreover, the combination of 3D imaging with augmented reality significantly improves surgical navigation process. The advantages of 3D imaging technology have made it an important component of technological progress in the field of medical imaging.

  19. New Promising Strategies in Oncofertility

    PubMed Central

    Hudson, Janella N.; Stanley, Nathanael B.; Nahata, Leena; Bowman-Curci, Meghan; Quinn, Gwendolyn P.

    2017-01-01

    Introduction Approximately 70,000 adolescent and young adults (AYA) are diagnosed with cancer each year. While advancements in treatment have led to improved prognosis and survival for patients, these same treatments can adversely affect AYA reproductive capacity. Localized treatments such as surgery and radiation therapy may affect fertility by removing or damaging reproductive organs, and systemic therapies such as chemotherapy can be toxic to gonads, (ovaries and testicles), thus affecting fertility and/or endocrine function. This can be traumatic for AYA with cancer as survivors often express desire to have genetic children and report feelings of regret or depression as a result of infertility caused by cancer treatments. Areas Covered Emerging technologies in the field of assisted reproductive technology offer new promise for preserving the reproductive capacity of AYA cancer patients prior to treatment as well as providing alternatives for survivors. The following review revisits contemporary approaches to fertility preservation as well newly developing technologies. Expert Commentary There are several advances in ART that hold promise for patients and survivors. However there are challenges that inhibit uptake including poor communication between providers and patients about risks and fertility preservation options; high costs; and lack of insurance coverage for fertility preservation services. PMID:28959743

  20. Childhood executive function inventory (CHEXI): a promising measure for identifying young children with ADHD?

    PubMed

    Thorell, Lisa B; Eninger, Lilianne; Brocki, Karin C; Bohlin, Gunilla

    2010-01-01

    The present study investigated whether the Childhood Executive Function Inventory (CHEXI) can discriminate between young children fulfilling the diagnostic criteria for attention-deficit/hyperactivity disorder (ADHD) and normally developing children. Unlike other executive function rating instruments, the CHEXI focuses specifically on inhibitory control and working memory, without including items that overlap with the diagnostic criteria of ADHD. The CHEXI was found to discriminate very well between children fulfilling the criteria for ADHD and normally developing children, also when controlling for the effect of IQ and socioeconomic status (SES). Both sensitivity and specificity of the two CHEXI subscales were shown to be high using either parent or teacher ratings. The highest overall classification rate was found for parent ratings on the inhibition subscale, with sensitivity and specificity reaching 93.3. To summarize, the CHEXI should be considered a promising measure for identifying young children with ADHD, although it is for future research to determine whether the CHEXI can be successfully used to also discriminate between different psychopathological groups.

  1. Technology of machine tools. Volume 1. Executive summary

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sutton, G.P.

    1980-10-01

    The Machine Tool Task Force (MTTF) was formed to characterize the state of the art of machine tool technology and to identify promising future directions of this technology. This volume is one of a five-volume series that presents the MTTF findings; reports on various areas of the technology were contributed by experts in those areas.

  2. Stem Cell Technology in Cardiac Regeneration: A Pluripotent Stem Cell Promise.

    PubMed

    Duelen, Robin; Sampaolesi, Maurilio

    2017-02-01

    Despite advances in cardiovascular biology and medical therapy, heart disorders are the leading cause of death worldwide. Cell-based regenerative therapies become a promising treatment for patients affected by heart failure, but also underline the need for reproducible results in preclinical and clinical studies for safety and efficacy. Enthusiasm has been tempered by poor engraftment, survival and differentiation of the injected adult stem cells. The crucial challenge is identification and selection of the most suitable stem cell type for cardiac regenerative medicine. Human pluripotent stem cells (PSCs) have emerged as attractive cell source to obtain cardiomyocytes (CMs), with potential applications, including drug discovery and toxicity screening, disease modelling and innovative cell therapies. Lessons from embryology offered important insights into the development of stem cell-derived CMs. However, the generation of a CM population, uniform in cardiac subtype, adult maturation and functional properties, is highly recommended. Moreover, hurdles regarding tumorigenesis, graft cell death, immune rejection and arrhythmogenesis need to be overcome in clinical practice. Here we highlight the recent progression in PSC technologies for the regeneration of injured heart. We review novel strategies that might overcome current obstacles in heart regenerative medicine, aiming at improving cell survival and functional integration after cell transplantation. Copyright © 2017. Published by Elsevier B.V.

  3. Using hyperspectral imaging technology to identify diseased tomato leaves

    NASA Astrophysics Data System (ADS)

    Li, Cuiling; Wang, Xiu; Zhao, Xueguan; Meng, Zhijun; Zou, Wei

    2016-11-01

    In the process of tomato plants growth, due to the effect of plants genetic factors, poor environment factors, or disoperation of parasites, there will generate a series of unusual symptoms on tomato plants from physiology, organization structure and external form, as a result, they cannot grow normally, and further to influence the tomato yield and economic benefits. Hyperspectral image usually has high spectral resolution, not only contains spectral information, but also contains the image information, so this study adopted hyperspectral imaging technology to identify diseased tomato leaves, and developed a simple hyperspectral imaging system, including a halogen lamp light source unit, a hyperspectral image acquisition unit and a data processing unit. Spectrometer detection wavelength ranged from 400nm to 1000nm. After hyperspectral images of tomato leaves being captured, it was needed to calibrate hyperspectral images. This research used spectrum angle matching method and spectral red edge parameters discriminant method respectively to identify diseased tomato leaves. Using spectral red edge parameters discriminant method produced higher recognition accuracy, the accuracy was higher than 90%. Research results have shown that using hyperspectral imaging technology to identify diseased tomato leaves is feasible, and provides the discriminant basis for subsequent disease control of tomato plants.

  4. The Promise of Technology. Proceedings of the Annual Conference on Rehabilitation Engineering (6th, San Diego, California, June 12-16, 1983). Volume 3.

    ERIC Educational Resources Information Center

    Bowman, Bruce R., Ed.

    These proceedings contain abstracts of 164 papers in the area of interdisciplinary rehabilitation research, focusing on the theme of "The Promise of Technology." The abstracts are organized into the following sections: "Home and Worksite Modification,""Computers and Microprocessor Systems,""Neuromuscular…

  5. Promising Results from Three NASA SBIR Solar Array Technology Development Programs

    NASA Technical Reports Server (NTRS)

    Eskenazi, Mike; White, Steve; Spence, Brian; Douglas, Mark; Glick, Mike; Pavlick, Ariel; Murphy, David; O'Neill, Mark; McDanal, A. J.; Piszczor, Michael

    2005-01-01

    Results from three NASA SBIR solar array technology programs are presented. The programs discussed are: 1) Thin Film Photovoltaic UltraFlex Solar Array; 2) Low Cost/Mass Electrostatically Clean Solar Array (ESCA); and 3) Stretched Lens Array SquareRigger (SLASR). The purpose of the Thin Film UltraFlex (TFUF) Program is to mature and validate the use of advanced flexible thin film photovoltaics blankets as the electrical subsystem element within an UltraFlex solar array structural system. In this program operational prototype flexible array segments, using United Solar amorphous silicon cells, are being manufactured and tested for the flight qualified UltraFlex structure. In addition, large size (e.g. 10 kW GEO) TFUF wing systems are being designed and analyzed. Thermal cycle and electrical test and analysis results from the TFUF program are presented. The purpose of the second program entitled, Low Cost/Mass Electrostatically Clean Solar Array (ESCA) System, is to develop an Electrostatically Clean Solar Array meeting NASA s design requirements and ready this technology for commercialization and use on the NASA MMS and GED missions. The ESCA designs developed use flight proven materials and processes to create a ESCA system that yields low cost, low mass, high reliability, high power density, and is adaptable to any cell type and coverglass thickness. All program objectives, which included developing specifications, creating ESCA concepts, concept analysis and trade studies, producing detailed designs of the most promising ESCA treatments, manufacturing ESCA demonstration panels, and LEO (2,000 cycles) and GEO (1,350 cycles) thermal cycling testing of the down-selected designs were successfully achieved. The purpose of the third program entitled, "High Power Platform for the Stretched Lens Array," is to develop an extremely lightweight, high efficiency, high power, high voltage, and low stowed volume solar array suitable for very high power (multi-kW to MW

  6. Democratic Citizenship and Information Technology: Promises, Challenges, and Remedies.

    ERIC Educational Resources Information Center

    White, Charles S.

    This paper examines the relationship between democratic citizenship and information technology. Modern information technology disputes the idea that citizens can be properly educated to assume the burdens necessary to reap the blessing of freedom. Information technologies challenge the ability of citizens to fulfill the fundamental requirement of…

  7. What it will take to achieve the as-yet-unfulfilled promises of health information technology.

    PubMed

    Kellermann, Arthur L; Jones, Spencer S

    2013-01-01

    A team of RAND Corporation researchers projected in 2005 that rapid adoption of health information technology (IT) could save the United States more than $81 billion annually. Seven years later the empirical data on the technology's impact on health care efficiency and safety are mixed, and annual health care expenditures in the United States have grown by $800 billion. In our view, the disappointing performance of health IT to date can be largely attributed to several factors: sluggish adoption of health IT systems, coupled with the choice of systems that are neither interoperable nor easy to use; and the failure of health care providers and institutions to reengineer care processes to reap the full benefits of health IT. We believe that the original promise of health IT can be met if the systems are redesigned to address these flaws by creating more-standardized systems that are easier to use, are truly interoperable, and afford patients more access to and control over their health data. Providers must do their part by reengineering care processes to take full advantage of efficiencies offered by health IT, in the context of redesigned payment models that favor value over volume.

  8. Technology of machine tools. Volume 4. Machine tool controls

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1980-10-01

    The Machine Tool Task Force (MTTF) was formed to characterize the state of the art of machine tool technology and to identify promising future directions of this technology. This volume is one of a five-volume series that presents the MTTF findings; reports on various areas of the technology were contributed by experts in those areas.

  9. Technology of machine tools. Volume 3. Machine tool mechanics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tlusty, J.

    1980-10-01

    The Machine Tool Task Force (MTTF) was formed to characterize the state of the art of machine tool technology and to identify promising future directions of this technology. This volume is one of a five-volume series that presents the MTTF findings; reports on various areas of the technology were contributed by experts in those areas.

  10. Technology of machine tools. Volume 5. Machine tool accuracy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hocken, R.J.

    1980-10-01

    The Machine Tool Task Force (MTTF) was formed to characterize the state of the art of machine tool technology and to identify promising future directions of this technology. This volume is one of a five-volume series that presents the MTTF findings; reports on various areas of the technology were contributed by experts in those areas.

  11. Control of oil spills in high speed currents : a technology assessment

    DOT National Transportation Integrated Search

    1999-05-01

    A technology assessment has been conducted to analyze the threat of oil spills in fast currents. Technologies and methods for response were evaluated, and promising equipment and strategies were identified. Recommendations are made to pursue those me...

  12. Visualizing Chemistry: The Progess and Promise of Advanced Chemical Imaging

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Committee on Revealing Chemistry Through Advanced Chemical Imaging

    2006-09-01

    The field of chemical imaging can provide detailed structural, functional, and applicable information about chemistry and chemical engineering phenomena that have enormous impacts on medicine, materials, and technology. In recognizing the potential for more research development in the field of chemical imaging, the National Academies was asked by the National Science Foundation, Department of Energy, U.S. Army, and National Cancer Institute to complete a study that would review the current state of molecular imaging technology, point to promising future developments and their applications, and suggest a research and educational agenda to enable breakthrough improvements in the ability to image molecularmore » processes simultaneously in multiple physical dimensions as well as time. The study resulted in a consensus report that provides guidance for a focused research and development program in chemical imaging and identifies research needs and possible applications of imaging technologies that can provide the breakthrough knowledge in chemistry, materials science, biology, and engineering for which we should strive. Public release of this report is expected in early October.« less

  13. Technology Integration Barriers: Urban School Mathematics Teachers Perspectives

    NASA Astrophysics Data System (ADS)

    Wachira, Patrick; Keengwe, Jared

    2011-02-01

    Despite the promise of technology in education, many practicing teachers face several challenges when trying to effectively integrate technology into their classroom instruction. Additionally, while national statistics cite a remarkable improvement in access to computer technology tools in schools, teacher surveys show consistent declines in the use and integration of computer technology to enhance student learning. This article reports on primary technology integration barriers that mathematics teachers identified when using technology in their classrooms. Suggestions to overcome some of these barriers are also provided.

  14. Understanding RNA modifications: the promises and technological bottlenecks of the ‘epitranscriptome’

    PubMed Central

    Kapoor, Utkarsh

    2017-01-01

    The discovery of mechanisms that alter genetic information via RNA editing or introducing covalent RNA modifications points towards a complexity in gene expression that challenges long-standing concepts. Understanding the biology of RNA modifications represents one of the next frontiers in molecular biology. To this date, over 130 different RNA modifications have been identified, and improved mass spectrometry approaches are still adding to this list. However, only recently has it been possible to map selected RNA modifications at single-nucleotide resolution, which has created a number of exciting hypotheses about the biological function of RNA modifications, culminating in the proposition of the ‘epitranscriptome’. Here, we review some of the technological advances in this rapidly developing field, identify the conceptual challenges and discuss approaches that are needed to rigorously test the biological function of specific RNA modifications. PMID:28566301

  15. PROMISE: a tool to identify genomic features with a specific biologically interesting pattern of associations with multiple endpoint variables.

    PubMed

    Pounds, Stan; Cheng, Cheng; Cao, Xueyuan; Crews, Kristine R; Plunkett, William; Gandhi, Varsha; Rubnitz, Jeffrey; Ribeiro, Raul C; Downing, James R; Lamba, Jatinder

    2009-08-15

    In some applications, prior biological knowledge can be used to define a specific pattern of association of multiple endpoint variables with a genomic variable that is biologically most interesting. However, to our knowledge, there is no statistical procedure designed to detect specific patterns of association with multiple endpoint variables. Projection onto the most interesting statistical evidence (PROMISE) is proposed as a general procedure to identify genomic variables that exhibit a specific biologically interesting pattern of association with multiple endpoint variables. Biological knowledge of the endpoint variables is used to define a vector that represents the biologically most interesting values for statistics that characterize the associations of the endpoint variables with a genomic variable. A test statistic is defined as the dot-product of the vector of the observed association statistics and the vector of the most interesting values of the association statistics. By definition, this test statistic is proportional to the length of the projection of the observed vector of correlations onto the vector of most interesting associations. Statistical significance is determined via permutation. In simulation studies and an example application, PROMISE shows greater statistical power to identify genes with the interesting pattern of associations than classical multivariate procedures, individual endpoint analyses or listing genes that have the pattern of interest and are significant in more than one individual endpoint analysis. Documented R routines are freely available from www.stjuderesearch.org/depts/biostats and will soon be available as a Bioconductor package from www.bioconductor.org.

  16. Educational Technology: Identifying the Effects.

    ERIC Educational Resources Information Center

    Hawkes, Mark; Cambre, Marge

    2001-01-01

    An evaluation of two school "telecommunities" in Ohio and South Dakota demonstrated the importance of studying a range of technology effectiveness indicators: standardized measures, behavior, stakeholder involvement, technology competency, multicultural exchange, equity, new student and teacher roles, learning climate, teacher…

  17. Identifying Students with Gifts and Talents in Technology. Technology

    ERIC Educational Resources Information Center

    Siegle, Del

    2004-01-01

    Technology expertise often occurs in two types of technology activities. One area of expertise is computer programming and another is expertise as a technology consumer using hardware and software. In addition to demonstrating prowess, some students tend to exhibit passion toward one or both of these activities. Students who excel in either could…

  18. NREL Helps Industry Partner Commercialize Promising Technology For Forest

    Science.gov Websites

    development agreement (CRADA) with Minerals Technologies, Inc. of Bethlehem, Penn. to conduct research to -shared research agreement is designed to provide Minerals Technologies, Inc. access to NREL's research

  19. Identifying/Quantifying Environmental Trade-offs Inherent in GHG Reduction Strategies for Coal-Fired Power. Environmental Science and Technology

    EPA Science Inventory

    Improvements to coal power plant technology and the co-fired combustion of biomass promise direct greenhouse gas (GHG) reductions for existing coal-fired power plants. Questions remain as to what the reduction potentials are from a life cycle perspective and if it will result in ...

  20. Network Computer Technology. Phase I: Viability and Promise within NASA's Desktop Computing Environment

    NASA Technical Reports Server (NTRS)

    Paluzzi, Peter; Miller, Rosalind; Kurihara, West; Eskey, Megan

    1998-01-01

    Over the past several months, major industry vendors have made a business case for the network computer as a win-win solution toward lowering total cost of ownership. This report provides results from Phase I of the Ames Research Center network computer evaluation project. It identifies factors to be considered for determining cost of ownership; further, it examines where, when, and how network computer technology might fit in NASA's desktop computing architecture.

  1. Composite Artistry Meets Facial Recognition Technology: Exploring the Use of Facial Recognition Technology to Identify Composite Images

    DTIC Science & Technology

    2011-09-01

    be submitted into a facial recognition program for comparison with millions of possible matches, offering abundant opportunities to identify the...to leverage the robust number of comparative opportunities associated with facial recognition programs. This research investigates the efficacy of...combining composite forensic artistry with facial recognition technology to create a viable investigative tool to identify suspects, as well as better

  2. New and emerging technologies for the diagnosis and monitoring of chronic obstructive pulmonary disease: A horizon scanning review.

    PubMed

    Dixon, Louise C; Ward, Derek J; Smith, Joanna; Holmes, Steve; Mahadeva, Ravi

    2016-03-11

    There is a need for straightforward, novel diagnostic and monitoring technologies to enable the early diagnosis of COPD and its differentiation from other respiratory diseases, to establish the cause of acute exacerbations and to monitor disease progression. We sought to establish whether technologies already in development could potentially address these needs. A systematic horizon scanning review was undertaken to identify technologies in development from a wide range of commercial and non-commercial sources. Technologies were restricted to those likely to be available within 18 months, and then evaluated for degree of innovation, potential for impact, acceptability to users and likelihood of adoption by clinicians and patients with COPD. Eighty technologies were identified, of which 25 were considered particularly promising. Biomarker tests, particularly those using sputum or saliva samples and/or available at the point of care, were positively evaluated, with many offering novel approaches to early diagnosis and to determining the cause for acute exacerbations. Several wrist-worn devices and smartphone-based spirometers offering the facility for self-monitoring and early detection of exacerbations were also considered promising. The most promising identified technologies have the potential to improve COPD care and patient outcomes. Further research and evaluation activities should be focused on these technologies. © The Author(s) 2016.

  3. Identifying and Researching Market Opportunities for New High Technology Products.

    ERIC Educational Resources Information Center

    Dunstan, Peter

    Using a product called the synchro-pulse welder as a case study example, this paper discusses the activities of CSIRO (Commonwealth Scientific and Industrial Research Organisation) in identifying and marketing new high-technology products. A general discussion of CSIRO's market research plans includes two goals to be attained within the next 5…

  4. Identifying Ghanaian Pre-Service Teachers' Readiness for Computer Use: A Technology Acceptance Model Approach

    ERIC Educational Resources Information Center

    Gyamfi, Stephen Adu

    2016-01-01

    This study extends the technology acceptance model to identify factors that influence technology acceptance among pre-service teachers in Ghana. Data from 380 usable questionnaires were tested against the research model. Utilising the extended technology acceptance model (TAM) as a research framework, the study found that: pre-service teachers'…

  5. Technology and Curriculum: Will the Promised Revolution Take Place?

    ERIC Educational Resources Information Center

    Mojkowski, Charles

    1987-01-01

    To take advantage of the emerging technological revolution, education must undertake its own revolution. Otherwise, technology will never be successfully integrated into the curriculum and may effect change without improvement. Primary focus must be on the future of curriculum and instruction, particularly discipline-specific process skills and…

  6. Supercritical fluid technology: a promising approach in pharmaceutical research.

    PubMed

    Girotra, Priti; Singh, Shailendra Kumar; Nagpal, Kalpana

    2013-02-01

    Supercritical fluids possess the unique properties of behaving like liquids and gases, above their critical point. Supercritical fluid technology has recently emerged as a green and novel technique for various processes such as solubility enhancement of poorly soluble drugs, plasticization of polymers, surface modification, nanosizing and nanocrystal modification, and chromatographic extraction. Research interest in this area has been fuelled because of the numerous advantages that the technology offers over the conventional methods. This work aims to review the merits, demerits, and various processes such as rapid expansion of supercritical solutions (RESS), particles from gas saturated solutions (PGSS), gas antisolvent process (GAS), supercritical antisolvent process (SAS) and polymerization induced phase separation (PIPS), that have enabled this technology to considerably raise the interest of researchers over the past two decades. An insight has been given into the numerous applications of this technology in pharmaceutical industry and the future challenges which must be appropriately dealt with to make it effective on a commercial scale.

  7. Project plan hydrogen energy systems technology. Phase 1: Hydrogen energy systems technology study

    NASA Technical Reports Server (NTRS)

    1974-01-01

    An overview of the potential need for hydrogen as a source of energy in the future was presented in order to identify and define the technology requirements for the most promising approaches to meet that need. The following study objectives were discussed: (1) determination of the future demand for hydrogen, based on current trends and anticipated new uses, (2) identification of the critical research and technology advances required to meet this need considering, to the extent possible, raw material limitations, economics, and environmental effects, and (3) definition and recommendation of the scope and space of a National Hydrogen Energy Systems Technology Program and outline of a Program Development Plan.

  8. Considerations for Realizing the Promise of Educational Gaming Technology

    ERIC Educational Resources Information Center

    Nelson, Nancy J.; Fien, Hank; Doabler, Christian T.; Clarke, Ben

    2016-01-01

    Hope Elementary School recently purchased tablets for all of its students to facilitate the use of technology in the classroom. The principal at Hope Elementary understands that technology can be an efficient and effective way for teachers to access materials and differentiate instruction to support the achievement of all learners. However, some…

  9. Predicting sudden cardiac death from T wave alternans of the surface electrocardiogram: promise and pitfalls

    NASA Technical Reports Server (NTRS)

    Rosenbaum, D. S.; Albrecht, P.; Cohen, R. J.

    1996-01-01

    Sudden cardiac death remains a preeminent public health problem. Despite advances in preventative treatment for patients known to be at risk, to date we have been able to identify, and thus treat, only a small minority of these patients. Therefore, there is a major need to develop noninvasive diagnostic technologies to identify patients at risk. Recent studies have demonstrated that measurement of microvolt-level T wave alternans is a promising technique for the accurate identification of patients at risk for ventricular arrhythmias and sudden cardiac death. In this article, we review the clinical data establishing the relationship between microvolt T wave alternans and susceptibility to ventricular arrhythmias. We also review the methods and technology that have been developed to measure microvolt levels of T wave alternans noninvasively in broad populations of ambulatory patients. In particular, we examine techniques that permit the accurate measurement of T wave alternans during exercise stress testing.

  10. Identifying Critical Issues and Problems in Technology Education Using a Modified-Delphi Technique.

    ERIC Educational Resources Information Center

    Wicklein, Robert C.

    1993-01-01

    Critical issues for technology education (TE) identified by a 25-member Delphi panel were identification of the knowledge base, curriculum development approaches, interdisciplinary approaches, and teacher education reform. Problems identified included inadequate marketing/public relations, teacher shortage, lack of content consensus, and…

  11. Technology of machine tools. Volume 2. Machine tool systems management and utilization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thomson, A.R.

    1980-10-01

    The Machine Tool Task Force (MTTF) was formed to characterize the state of the art of machine tool technology and to identify promising future directions of this technology. This volume is one of a five-volume series that presents the MTTF findings; reports on various areas of the technology were contributed by experts in those areas.

  12. Making processes reliable: a validated pubmed search strategy for identifying new or emerging technologies.

    PubMed

    Varela-Lema, Leonora; Punal-Riobóo, Jeanette; Acción, Beatriz Casal; Ruano-Ravina, Alberto; García, Marisa López

    2012-10-01

    Horizon scanning systems need to handle a wide range of sources to identify new or emerging health technologies. The objective of this study is to develop a validated Medline bibliographic search strategy (PubMed search engine) to systematically identify new or emerging health technologies. The proposed Medline search strategy combines free text terms commonly used in article titles to denote innovation within index terms that make reference to the specific fields of interest. Efficacy was assessed by running the search over a period of 1 year (2009) and analyzing its retrieval performance (number and characteristics). For comparison purposes, all article abstracts published during 2009 in six preselected key research journals and eight high impact surgery journals were scanned. Sensitivity was defined as the proportion of relevant new or emerging technologies published in key journals that would be identified in the search strategy within the first 2 years of publication. The search yielded 6,228 abstracts of potentially new or emerging technologies. Of these, 459 were classified as new or emerging (383 truly new or emerging and 76 new indications). The scanning of 12,061 journal abstracts identified 35 relevant new or emerging technologies. Of these, twenty-nine were located within the Medline search strategy during the first 2 years of publication (sensitivity = 83 percent). The current search strategy, validated against key journals, has demonstrated to be effective for horizon scanning. Even though it can require adaptations depending on the scope of the horizon scanning system, it could serve to simplify and standardize scanning processes.

  13. Innovative new technologies to identify and treat traumatic brain injuries: crossover technologies and approaches between military and civilian applications.

    PubMed

    Doarn, Charles R; McVeigh, Francis; Poropatich, Ronald

    2010-04-01

    Traumatic brain injury (TBI) has become the signature injury of Operation Iraqi Freedom and Operation Enduring Freedom. The use of improvised explosive devices has seen an exponential increase in both Iraq and Afghanistan. In previous conflicts prior to Iraq, survivability of such an injury was far less. Today, technological improvements in trauma care have increased an injured warfighter's chance of survival. A reduction in severe TBI has been achieved but an increase in mild or moderate TBI has been observed. The consequences of this kind of injury can be both physical and mental and can often be hidden or even misdiagnosed. The U.S. Army is interested in pursuing technological solutions for early detection and treatment of TBI to reduce its lasting impact on the warfighter. Such technological breakthroughs have benefit beyond the military, as TBI is a high probable event in nonmilitary settings as well. To gauge what technologies or methods are currently available, the U.S. Army's Telemedicine and Advanced Technology Research Center partnered with the American Telemedicine Association to organize and conduct a discipline-specific symposium entitled "Innovative New Technologies to Identify and Treat Traumatic Brain Injuries: Crossover Technologies and Approaches Between Military and Civilian Applications." This symposium was held in Palm Springs, CA, in September 2009. The purpose of the meeting was to provide a unique opportunity for leaders from disparate organizations involved in telemedicine and related other activities to meet and explore opportunities to collaborate in new partnership models. The meeting was designed to help Telemedicine and Advanced Technology Research Center identify opportunities to expand strategic operations and form new alliances. This report summarizes this symposium while raising awareness for collaboration into better ways of adapting and adopting technologies to address this growing health issue.

  14. The promise of new ideas and new technology for improving teaching and learning.

    PubMed

    Novak, Joseph D

    2003-01-01

    There have been enormous advances in our understanding of human learning in the past three decades. There have also been important advances in our understanding of the nature of knowledge and new knowledge creation. These advances, when combined with the explosive development of the Internet and other technologies, permit advances in educational practices at least as important as the invention of the printing press in 1460. We have built on the cognitive learning theory of David Ausubel and various sources of new ideas on epistemology. Our research program has focused on understanding meaningful learning and on developing better methods to achieve such learning and to assess progress in meaningful learning. The concept map tool developed in our program has proved to be highly effective both in promoting meaningful learning and in assessing learning outcomes. Concept mapping strategies are also proving powerful for eliciting, capturing, and archiving knowledge of experts and organizations. New technology for creating concept maps developed at the University of West Florida permits easier and better concept map construction, thus facilitating learning, knowledge capture, and local or distance creation and sharing of structured knowledge, especially when utilized with the Internet. A huge gap exists between what we now know to improve learning and use of knowledge and the practices currently in place in most schools and corporations. There are promising projects in progress that may help to achieve accelerated advances. These include projects in schools at all educational levels, including projects in Colombia, Costa Rica, Italy, Spain, and the United States, and collaborative projects with corporate organizations and distance learning projects. Results to date have been encouraging and suggest that we may be moving from the lag phase of educational innovation to a phase of exponential growth.

  15. The Promise of New Ideas and New Technology for Improving Teaching and Learning

    PubMed Central

    Novak, Joseph D.

    2003-01-01

    There have been enormous advances in our understanding of human learning in the past three decades. There have also been important advances in our understanding of the nature of knowledge and new knowledge creation. These advances, when combined with the explosive development of the Internet and other technologies, permit advances in educational practices at least as important as the invention of the printing press in 1460. We have built on the cognitive learning theory of David Ausubel and various sources of new ideas on epistemology. Our research program has focused on understanding meaningful learning and on developing better methods to achieve such learning and to assess progress in meaningful learning. The concept map tool developed in our program has proved to be highly effective both in promoting meaningful learning and in assessing learning outcomes. Concept mapping strategies are also proving powerful for eliciting, capturing, and archiving knowledge of experts and organizations. New technology for creating concept maps developed at the University of West Florida permits easier and better concept map construction, thus facilitating learning, knowledge capture, and local or distance creation and sharing of structured knowledge, especially when utilized with the Internet. A huge gap exists between what we now know to improve learning and use of knowledge and the practices currently in place in most schools and corporations. There are promising projects in progress that may help to achieve accelerated advances. These include projects in schools at all educational levels, including projects in Colombia, Costa Rica, Italy, Spain, and the United States, and collaborative projects with corporate organizations and distance learning projects. Results to date have been encouraging and suggest that we may be moving from the lag phase of educational innovation to a phase of exponential growth. PMID:12888848

  16. PROMISE: a tool to identify genomic features with a specific biologically interesting pattern of associations with multiple endpoint variables

    PubMed Central

    Pounds, Stan; Cheng, Cheng; Cao, Xueyuan; Crews, Kristine R.; Plunkett, William; Gandhi, Varsha; Rubnitz, Jeffrey; Ribeiro, Raul C.; Downing, James R.; Lamba, Jatinder

    2009-01-01

    Motivation: In some applications, prior biological knowledge can be used to define a specific pattern of association of multiple endpoint variables with a genomic variable that is biologically most interesting. However, to our knowledge, there is no statistical procedure designed to detect specific patterns of association with multiple endpoint variables. Results: Projection onto the most interesting statistical evidence (PROMISE) is proposed as a general procedure to identify genomic variables that exhibit a specific biologically interesting pattern of association with multiple endpoint variables. Biological knowledge of the endpoint variables is used to define a vector that represents the biologically most interesting values for statistics that characterize the associations of the endpoint variables with a genomic variable. A test statistic is defined as the dot-product of the vector of the observed association statistics and the vector of the most interesting values of the association statistics. By definition, this test statistic is proportional to the length of the projection of the observed vector of correlations onto the vector of most interesting associations. Statistical significance is determined via permutation. In simulation studies and an example application, PROMISE shows greater statistical power to identify genes with the interesting pattern of associations than classical multivariate procedures, individual endpoint analyses or listing genes that have the pattern of interest and are significant in more than one individual endpoint analysis. Availability: Documented R routines are freely available from www.stjuderesearch.org/depts/biostats and will soon be available as a Bioconductor package from www.bioconductor.org. Contact: stanley.pounds@stjude.org Supplementary information: Supplementary data are available at Bioinformatics online. PMID:19528086

  17. Metabolomic Technologies for Improving the Quality of Food: Practice and Promise.

    PubMed

    Johanningsmeier, Suzanne D; Harris, G Keith; Klevorn, Claire M

    2016-01-01

    It is now well documented that the diet has a significant impact on human health and well-being. However, the complete set of small molecule metabolites present in foods that make up the human diet and the role of food production systems in altering this food metabolome are still largely unknown. Metabolomic platforms that rely on nuclear magnetic resonance (NMR) and mass spectrometry (MS) analytical technologies are being employed to study the impact of agricultural practices, processing, and storage on the global chemical composition of food; to identify novel bioactive compounds; and for authentication and region-of-origin classifications. This review provides an overview of the current terminology, analytical methods, and compounds associated with metabolomic studies, and provides insight into the application of metabolomics to generate new knowledge that enables us to produce, preserve, and distribute high-quality foods for health promotion.

  18. The engagement of children with disabilities in health-related technology design processes: identifying methodology.

    PubMed

    Allsop, Matthew J; Holt, Raymond J; Levesley, Martin C; Bhakta, Bipinchandra

    2010-01-01

    This review aims to identify research methodology that is suitable for involving children with disabilities in the design of healthcare technology, such as assistive technology and rehabilitation equipment. A review of the literature included the identification of methodology that is available from domains outside of healthcare and suggested a selection of available methods. The need to involve end users within the design of healthcare technology was highlighted, with particular attention to the need for greater levels of participation from children with disabilities within all healthcare research. Issues that may arise when trying to increase such involvement included the need to consider communication via feedback and tailored information, the need to measure levels of participation occurring in current research, and caution regarding the use of proxy information. Additionally, five suitable methods were highlighted that are available for use with children with disabilities in the design of healthcare technology. The methods identified in the review need to be put into practice to establish effective and, if necessary, novel ways of designing healthcare technology when end users are children with disabilities.

  19. Fulfilling the promise of holographic optical elements

    NASA Astrophysics Data System (ADS)

    Moss, Gaylord E.

    1990-05-01

    Consider the whole class of holographic optical elements which either contain pictorial image information or have the ability to modify wavefronts. Even after many years of development, there are pitifully few marketable applications. The visionary promises that holography would create a revolution in the optics and display industries have not been fulfilled. Time has shown that, while it was relatively simple to dream up ideas for myriad applications, these ideas have generally not moved beyond laboratory demonstrations. Exceptions are a few items such as optical elements for supermarket scanners, head-up displays and laser diode lenses. This paper addresses: 1. The many promises of holographic elements 2. The difficulties of practical implementation 3. A reassessment of research and development priorities To give simple examples of these points, they are discussed mainly as they apply to one type of holographic application: automotive displays. These familiar displays give a clear example of both the promises and difficulties that holographic elements present in the world of high volume, low-costproduction. Automotive displays could be considered as a trivial application alongside more interesting fundamental research programs or high cost, sophisticated military applications. One might even consider "trivial" automotive displays to be a disreputable subject for serious researchers. The case is made that exactly the opposite is true. The resources for large scale development exist only in a healthy commercial market. An example is the Japanese funding of high technology through commercial product development. This has been shown to be effective in the development of other technologies, such as ceramics, semiconductors, solar cells and composite materials. In like manner, if holography is to become an economically important technology, more and more competent researchers must start looking outside the universities and military laboratories for support. They must

  20. Identifying and tracking disaster victims: state-of-the-art technology review.

    PubMed

    Pate, Barbara L

    2008-01-01

    The failure of our nation to adequately track victims of Hurricane Katrina has been identified as a major weakness of national and local disaster preparedness plans. This weakness has prompted government and private industries to acknowledge that existing paper-based tracking systems are incapable of managing information during a large-scale disaster. In response to this need, efforts are under way to develop new technologies that allow instant access to identity and location information during emergency situations. The purpose of this article is to provide a review of state-of-the-art technologies, with implications and limitations for use during mass casualty incidents.

  1. Biomass torrefaction: A promising pretreatment technology for biomass utilization

    NASA Astrophysics Data System (ADS)

    Chen, ZhiWen; Wang, Mingfeng; Ren, Yongzhi; Jiang, Enchen; Jiang, Yang; Li, Weizhen

    2018-02-01

    Torrefaction is an emerging technology also called mild pyrolysis, which has been explored for the pretreatment of biomass to make the biomass more favorable for further utilization. Dry torrefaction (DT) is a pretreatment of biomass in the absence of oxygen under atmospheric pressure and in a temperature range of 200-300 degrees C, while wet torrrefaction (WT) is a method in hydrothermal or hot and high pressure water at the tempertures within 180-260 degrees C. Torrrefied biomass is hydrophobic, with lower moisture contents, increased energy density and higher heating value, which are more comparable to the characteristics of coal. With the improvement in the properties, torrefied biomass mainly has three potential applications: combustion or co-firing, pelletization and gasification. Generally, the torrefaction technology can accelerate the development of biomass utilization technology and finally realize the maximum applications of biomass energy.

  2. Aerospace Technology Innovation. Volume 10

    NASA Technical Reports Server (NTRS)

    Turner, Janelle (Editor); Cousins, Liz (Editor); Bennett, Evonne (Editor); Vendette, Joel (Editor); West, Kenyon (Editor)

    2002-01-01

    Whether finding new applications for existing NASA technologies or developing unique marketing strategies to demonstrate them, NASA's offices are committed to identifying unique partnering opportunities. Through their efforts NASA leverages resources through joint research and development, and gains new insight into the core areas relevant to all NASA field centers. One of the most satisfying aspects of my job comes when I learn of a mission-driven technology that can be spun-off to touch the lives of everyday people. NASA's New Partnerships in Medical Diagnostic Imaging is one such initiative. Not only does it promise to provide greater dividends for the country's investment in aerospace research, but also to enhance the American quality of life. This issue of Innovation highlights the new NASA-sponsored initiative in medical imaging. Early in 2001, NASA announced the launch of the New Partnerships in Medical Diagnostic Imaging initiative to promote the partnership and commercialization of NASA technologies in the medical imaging industry. NASA and the medical imaging industry share a number of crosscutting technologies in areas such as high-performance detectors and image-processing tools. Many of the opportunities for joint development and technology transfer to the medical imaging market also hold the promise for future spin back to NASA.

  3. Operationally Efficient Propulsion System Study (OEPSS) data book. Volume 3: Operations technology

    NASA Technical Reports Server (NTRS)

    Vilja, John O.

    1990-01-01

    The study was initiated to identify operational problems and cost drivers for current propulsion systems and to identify technology and design approaches to increase the operational efficiency and reduce operations costs for future propulsion systems. To provide readily usable data for the Advanced Launch System (ALS) program, the results of the OEPSS study were organized into a series of OEPSS Data Books. This volume describes operations technologies that will enhance operational efficiency of propulsion systems. A total of 15 operations technologies were identified that will eliminate or mitigate operations problems described in Volume 2. A recommended development plan is presented for eight promising technologies that will simplify the propulsion system and reduce operational requirements.

  4. Approaches to Identifying the Emerging Innovative Water Technology Industry in the United States

    PubMed Central

    WOOD, ALLISON R.; HARTEN, TERESA; GUTIERREZ, SALLY C.

    2018-01-01

    Clean water is vital to sustaining our natural environment, human health, and our economy. As infrastructure continues to deteriorate and water resources become increasingly threatened, new technologies will be needed to ensure safe and sustainable water in the future. Though the US water industry accounts for approximately 1% gross domestic product and regional “clusters” for water technology exist throughout the country, this emerging industry has not been captured by recent studies. As use of the term “cluster” becomes more prevalent, regional mapping efforts have revealed international differences in definition yet showcase this industry’s economic impact. In reality, institutional processes may inhibit altering industry coding to better describe water technology. Forgoing the benefits of national economic tracking, alternative data sets are available, which may support new ways of identifying these clusters. This work provides cluster definitions; summarizes current approaches to identifying industry activity using data, interviews, and literature; and sets a foundation for future research. PMID:29937546

  5. Approaches to Identifying the Emerging Innovative Water Technology Industry in the United States.

    PubMed

    Wood, Allison R; Harten, Teresa; Gutierrez, Sally C

    2018-04-25

    Clean water is vital to sustaining our natural environment, human health, and our economy. As infrastructure continues to deteriorate and water resources become increasingly threatened, new technologies will be needed to ensure safe and sustainable water in the future. Though the US water industry accounts for approximately 1% gross domestic product and regional "clusters" for water technology exist throughout the country, this emerging industry has not been captured by recent studies. As use of the term "cluster" becomes more prevalent, regional mapping efforts have revealed international differences in definition yet showcase this industry's economic impact. In reality, institutional processes may inhibit altering industry coding to better describe water technology. Forgoing the benefits of national economic tracking, alternative data sets are available, which may support new ways of identifying these clusters. This work provides cluster definitions; summarizes current approaches to identifying industry activity using data, interviews, and literature; and sets a foundation for future research.

  6. Cost-effectiveness analysis: problems and promise for evaluating medical technology

    NASA Astrophysics Data System (ADS)

    Juday, Timothy R.

    1994-12-01

    Although using limited financial resources in the most beneficial way, in principle, a laudable goal, actually developing standards for measuring the cost-effectiveness of medical technologies and incorporating them into the coverage process is a much more difficult proposition. Important methodological difficulties include determining how to compare a technology to its leading alternative, defining costs, incorporating patient preferences, and defining health outcomes. In addition, more practical questions must be addressed. These questions include: who does the analysis? who makes the decisions? which technologies to evaluate? what resources are required? what is the political and legal environment? how much is a health outcome worth? The ultimate question that must be answered is what is a health outcome worth? Cost-effectiveness analysis cannot answer this question; it only enables comparison of cost-effectiveness ratios across technologies. In order to determine whether a technology should be covered, society or individual insurers must determine how much they are willing to pay for the health benefits. Conducting cost-effectiveness analysis will not remove the need to make difficult resource allocation decisions; however, explicitly examining the tradeoffs involved in these decisions should help to improve the process.

  7. Report Outlines Promising Opportunities for Addressing Climate Change

    Science.gov Websites

    Report Outlines Promising Opportunities for Addressing Climate Change For more information contact , have issued a major report that finds the United States can make impressive strides toward addressing climate change through smart policies and technologies. The report, "Scenarios for a Clean Energy

  8. Seduction or Productivity: Repurposing the Promise of Technology

    ERIC Educational Resources Information Center

    Klein, William; Duffey, Suellynn

    2009-01-01

    In tight financial climates, emerging technologies loom as enticing options to administrators: efficient and cost-effective solutions to both operational and pedagogical problems. Disciplinary knowledge, frequently hailed as the pinnacle of cultural capital in the academy, does not hold absolute power in rhetorical situations in which the material…

  9. NASA Development of Aerocapture Technologies

    NASA Technical Reports Server (NTRS)

    James, Bonnie; Munk, Michelle; Moon, Steve

    2003-01-01

    Aeroassist technology development is a vital part of the NASA ln-Space Propulsion Program (ISP), which is managed by the NASA Headquarters Office of Space Science, and implemented by the Marshall Space Flight Center in Huntsville, Alabama. Aeroassist is the general term given to various techniques to maneuver a space vehicle within an atmosphere, using aerodynamic forces in lieu of propulsive fuel. Within the ISP, the current aeroassist technology development focus is aerocapture. The objective of the ISP Aerocapture Technology Project (ATP) is to develop technologies that can enable and/or benefit NASA science missions by significantly reducing cost, mass, and/or travel times. To accomplish this objective, the ATP identifies and prioritizes the most promising technologies using systems analysis, technology advancement and peer review, coupled with NASA Headquarters Office of Space Science target requirements. Plans are focused on developing mid-Technology Readiness Level (TRL) technologies to TRL 6 (ready for technology demonstration in space).

  10. NASA Development of Aerocapture Technologies

    NASA Technical Reports Server (NTRS)

    James, Bonnie; Munk, Michelle; Moon, Steve

    2004-01-01

    Aeroassist technology development is a vital part of the NASA In-Space Propulsion Program (ISP), which is managed by the NASA Headquarters Office of Space Science, and implemented by the Marshall Space Flight Center in Huntsville, Alabama. Aeroassist is the general term given to various techniques to maneuver a space vehicle within an atmosphere, using aerodynamic forces in lieu of propulsive fuel. Within the ISP, the current aeroassist technology development focus is aerocapture. The objective of the ISP Aerocapture Technology Project (ATP) is to develop technologies that can enable and/or benefit NASA science missions by significantly reducing cost, mass, and/or travel times. To accomplish this objective, the ATP identifies and prioritizes the most promising technologies using systems analysis, technology advancement and peer review, coupled with NASA Headquarters Office of Space Science target requirements. Plans are focused on developing mid-Technology Readiness Level (TRL) technologies to TRL 6 (ready for technology demonstration in space).

  11. Nebraska Industrial Technology Education Teachers Identify the Equipment Their Students Use.

    ERIC Educational Resources Information Center

    Rogers, George E.

    A study asked 287 industrial technology education (ITE) teachers in Nebraska to identify what equipment was being used by ITE students. It also compared ITE equipment usage with regard to school type and school size. The response rate was 59.2 percent (n=170). Findings indicated the drill press and band saw were the most widely used pieces of…

  12. Technology in Education: Its Prospects and Its Promises.

    ERIC Educational Resources Information Center

    Senese, Donald J.

    The impact of advanced technology has increased computer usage at all levels as evidenced by the popularity of video games, increased interest on the part of students using computers to enhance learning, and business/school partnerships forming with such companies as Digital Equipment Corporation, International Business Machines, and Tandy/Radio…

  13. Patent Network Analysis and Quadratic Assignment Procedures to Identify the Convergence of Robot Technologies

    PubMed Central

    Lee, Woo Jin; Lee, Won Kyung

    2016-01-01

    Because of the remarkable developments in robotics in recent years, technological convergence has been active in this area. We focused on finding patterns of convergence within robot technology using network analysis of patents in both the USPTO and KIPO. To identify the variables that affect convergence, we used quadratic assignment procedures (QAP). From our analysis, we observed the patent network ecology related to convergence and found technologies that have great potential to converge with other robotics technologies. The results of our study are expected to contribute to setting up convergence based R&D policies for robotics, which can lead new innovation. PMID:27764196

  14. Y-12 Plant decontamination and decommissioning technology logic diagram for Building 9201-4. Volume 2: Technology logic diagram

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1994-09-01

    The Y-12 Plant Decontamination and Decommissioning Technology Logic Diagram for Building 9201-4 (TLD) was developed to provide a decision-support tool that relates decontamination and decommissioning (D and D) problems at Bldg. 9201-4 to potential technologies that can remediate these problems. This TLD identifies the research, development, demonstration, testing, and evaluation needed for sufficient development of these technologies to allow for technology transfer and application to D and D and waste management (WM) activities. It is essential that follow-on engineering studies be conducted to build on the output of this project. These studies will begin by selecting the most promising technologiesmore » identified in the TLD and by finding an optimum mix of technologies that will provide a socially acceptable balance between cost and risk. The TLD consists of three fundamentally separate volumes: Vol. 1 (Technology Evaluation), Vol. 2 (Technology Logic Diagram), and Vol. 3 (Technology Evaluation Data Sheets). Volume 2 contains the logic linkages among environmental management goals, environmental problems, and the various technologies that have the potential to solve these problems. Volume 2 has been divided into five sections: Characterization, Decontamination, Dismantlement, Robotics/Automation, and Waste Management. Each section contains logical breakdowns of the Y-12 D and D problems by subject area and identifies technologies that can be reasonably applied to each D and D challenge.« less

  15. License Agreement Moves Promising Technology Into the Marketplace

    Science.gov Websites

    generated every day by sewage treatment plants. The pretreatment process was developed at the U.S commercialize the technology to Peak Treatment Systems, Inc. of Golden, Colo. Conventional disposal methods completely broken down. Peak Treatment Systems is using the equipment at a pilot-scale high solids anaerobic

  16. Promising Practices in Career and Technology Studies (CTS).

    ERIC Educational Resources Information Center

    Alberta Learning, Edmonton. Learning and Teaching Resources Branch.

    This document contains profiles of 130 successful programs and partnerships in Career and Technology Studies (CTS) in Alberta, Canada. Following an introduction to the CTS program and its implementation, the profiles are organized into 23 sections that follow the strands of the program. The sections cover the following topics: CTS general;…

  17. Paradigm Shift: The New Promise of Information Technology.

    ERIC Educational Resources Information Center

    Tapscott, Don; Caston, Art

    A fundamental change is taking place in the nature and application of technology in business, a change with profound and far-reaching implications for companies of every size and shape. A multimillion dollar research program conducted by the DMR Group, Inc., studied more than 4,500 organizations in North America, Europe, and the Far East to…

  18. Safety huddles to proactively identify and address electronic health record safety

    PubMed Central

    Menon, Shailaja; Singh, Hardeep; Giardina, Traber D; Rayburn, William L; Davis, Brenda P; Russo, Elise M

    2017-01-01

    Objective: Methods to identify and study safety risks of electronic health records (EHRs) are underdeveloped and largely depend on limited end-user reports. “Safety huddles” have been found useful in creating a sense of collective situational awareness that increases an organization’s capacity to respond to safety concerns. We explored the use of safety huddles for identifying and learning about EHR-related safety concerns. Design: Data were obtained from daily safety huddle briefing notes recorded at a single midsized tertiary-care hospital in the United States over 1 year. Huddles were attended by key administrative, clinical, and information technology staff. We conducted a content analysis of huddle notes to identify what EHR-related safety concerns were discussed. We expanded a previously developed EHR-related error taxonomy to categorize types of EHR-related safety concerns recorded in the notes. Results: On review of daily huddle notes spanning 249 days, we identified 245 EHR-related safety concerns. For our analysis, we defined EHR technology to include a specific EHR functionality, an entire clinical software application, or the hardware system. Most concerns (41.6%) involved “EHR technology working incorrectly,” followed by 25.7% involving “EHR technology not working at all.” Concerns related to “EHR technology missing or absent” accounted for 16.7%, whereas 15.9% were linked to “user errors.” Conclusions: Safety huddles promoted discussion of several technology-related issues at the organization level and can serve as a promising technique to identify and address EHR-related safety concerns. Based on our findings, we recommend that health care organizations consider huddles as a strategy to promote understanding and improvement of EHR safety. PMID:28031286

  19. Promises, promises for neuroscience and law.

    PubMed

    Buckholtz, Joshua W; Faigman, David L

    2014-09-22

    Stunning technical advances in the ability to image the human brain have provoked excited speculation about the application of neuroscience to other fields. The 'promise' of neuroscience for law has been touted with particular enthusiasm. Here, we contend that this promise elides fundamental conceptual issues that limit the usefulness of neuroscience for law. Recommendations for overcoming these challenges are offered. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Keeping Promises

    NASA Technical Reports Server (NTRS)

    Howell, Gregory A.

    2005-01-01

    Commitments are between people, not schedules. Project management as practiced today creates a "commitment-free zone," because it assumes that people will commit to centrally managed schedules without providing a mechanism to ensure their work can be done. So they give it their best, but something always seems to come up ..."I tried, but you know how it is." This form of project management does not provide a mechanism to ensure that what should be done, can in fact be done at the required moment. Too often, promises reliable promise. made in coordination meetings are conditional and unreliable. It has been my experience that at times trust can be low and hard to build in this environment. The absence of reliable promises explains why on well-run projects, people are often only completing 30-50 percent of the deliverables they d promised for the week. We all know what a promise is; we have plenty of experience making them and receiving them from others. So what s the problem? The sad fact is that the project environment-like many other work environments- is often so filled with systemic dishonesty, that we don t expect promises that are reliable. Project managers excel when they manage their projects as networks of commitments and help their people learn to elicit and make reliable promises.

  1. Promise and Progress of Millihertz Gravitational-Wave Astronomy

    NASA Technical Reports Server (NTRS)

    Baker, John G.

    2017-01-01

    Extending the new field of gravitational wave (GW) astronomy into the millihertz band with a space-based GW observatory is a high-priority objective of international astronomy community. This paper summarizes the astrophysical promise and the technological groundwork for such an observatory, concretely focusing on the prospects for the proposed Laser Interferometer Space Antenna (LISA) mission concept.

  2. The Virtual Combat Air Staff. The Promise of Information Technologies,

    DTIC Science & Technology

    1996-08-07

    development of specialists . The need for advance planning and orchestration of a growing variety of sup- port functions has required the commander to... ability for almost unlim- ited access to command authorities and fielded forces via worldwide communications, increased situational awareness, and the...mercially developed systems that incorporate the latest technologies, training programs will have to adapt to the rapid pace at which such technologies are

  3. KSC Education Technology Research and Development Plan

    NASA Technical Reports Server (NTRS)

    Odell, Michael R. L.

    2003-01-01

    Educational technology is facilitating new approaches to teaching and learning science, technology, engineering, and mathematics (STEM) education. Cognitive research is beginning to inform educators about how students learn providing a basis for design of more effective learning environments incorporating technology. At the same time, access to computers, the Internet and other technology tools are becoming common features in K-20 classrooms. Encouraged by these developments, STEM educators are transforming traditional STEM education into active learning environments that hold the promise of enhancing learning. This document illustrates the use of technology in STEM education today, identifies possible areas of development, links this development to the NASA Strategic Plan, and makes recommendations for the Kennedy Space Center (KSC) Education Office for consideration in the research, development, and design of new educational technologies and applications.

  4. Optimizing substance detection by integration of canine-human team with machine technology

    NASA Astrophysics Data System (ADS)

    Prestrude, Al M.; Ternes, J. W.

    1994-02-01

    There are several promising methods and technologies for substance detection. The oldest of these methods is the trained detector or `sniffer' dog. We summarize what is known about the capabilities of dogs in substance detection and recommend comparative testing of the canine- human team with current technology to identify the optimum combination of methods to maximize the detection of explosives and contraband.

  5. Solutions for Failing High Schools: Converging Visions and Promising Models.

    ERIC Educational Resources Information Center

    Legters, Nettie; Balfanz, Robert; McPartland, James

    Promising solutions to the failings of traditional comprehensive high schools were reviewed to identify basic principles and strategies for improving high schools nationwide. Selected research studies, policy documents, and promising high school programs were reviewed. The review revealed the following principles for helping high schools better…

  6. Stromquist, N., & Samoff, J. (2000). Knowledge Management Systems: On the Promise and Actual Forms of Information Technologies. "British Association for International and Comparative Education," 30(3), 323-332

    ERIC Educational Resources Information Center

    Gramlich, Catherine

    2003-01-01

    In their article," Knowledge Management Systems: On the Promise and Actual Forms of Information Technologies, Stromquist and Samoff (2000)" critically examined the role of Knowledge Management Systems (KMS) in education. Stromquist and Samoff (2000) defined a KMS as a system "which proposes to produce easily retrievable materials…

  7. Participant Observation: A Promising Research Approach for Educational Technology

    ERIC Educational Resources Information Center

    Dodge, Martin; Bogdan, Robert

    1974-01-01

    Symbolic interaction is a useful perspective, a viable theoretical approach to getting at answers to many important questions related to educational technology. Participant observation is a useful methodology for rooting answers out of the research setting. (Author)

  8. Identifying the science and technology dimensions of emerging public policy issues through horizon scanning.

    PubMed

    Parker, Miles; Acland, Andrew; Armstrong, Harry J; Bellingham, Jim R; Bland, Jessica; Bodmer, Helen C; Burall, Simon; Castell, Sarah; Chilvers, Jason; Cleevely, David D; Cope, David; Costanzo, Lucia; Dolan, James A; Doubleday, Robert; Feng, Wai Yi; Godfray, H Charles J; Good, David A; Grant, Jonathan; Green, Nick; Groen, Arnoud J; Guilliams, Tim T; Gupta, Sunjai; Hall, Amanda C; Heathfield, Adam; Hotopp, Ulrike; Kass, Gary; Leeder, Tim; Lickorish, Fiona A; Lueshi, Leila M; Magee, Chris; Mata, Tiago; McBride, Tony; McCarthy, Natasha; Mercer, Alan; Neilson, Ross; Ouchikh, Jackie; Oughton, Edward J; Oxenham, David; Pallett, Helen; Palmer, James; Patmore, Jeff; Petts, Judith; Pinkerton, Jan; Ploszek, Richard; Pratt, Alan; Rocks, Sophie A; Stansfield, Neil; Surkovic, Elizabeth; Tyler, Christopher P; Watkinson, Andrew R; Wentworth, Jonny; Willis, Rebecca; Wollner, Patrick K A; Worts, Kim; Sutherland, William J

    2014-01-01

    Public policy requires public support, which in turn implies a need to enable the public not just to understand policy but also to be engaged in its development. Where complex science and technology issues are involved in policy making, this takes time, so it is important to identify emerging issues of this type and prepare engagement plans. In our horizon scanning exercise, we used a modified Delphi technique. A wide group of people with interests in the science and policy interface (drawn from policy makers, policy adviser, practitioners, the private sector and academics) elicited a long list of emergent policy issues in which science and technology would feature strongly and which would also necessitate public engagement as policies are developed. This was then refined to a short list of top priorities for policy makers. Thirty issues were identified within broad areas of business and technology; energy and environment; government, politics and education; health, healthcare, population and aging; information, communication, infrastructure and transport; and public safety and national security.

  9. Identifying the Science and Technology Dimensions of Emerging Public Policy Issues through Horizon Scanning

    PubMed Central

    Parker, Miles; Acland, Andrew; Armstrong, Harry J.; Bellingham, Jim R.; Bland, Jessica; Bodmer, Helen C.; Burall, Simon; Castell, Sarah; Chilvers, Jason; Cleevely, David D.; Cope, David; Costanzo, Lucia; Dolan, James A.; Doubleday, Robert; Feng, Wai Yi; Godfray, H. Charles J.; Good, David A.; Grant, Jonathan; Green, Nick; Groen, Arnoud J.; Guilliams, Tim T.; Gupta, Sunjai; Hall, Amanda C.; Heathfield, Adam; Hotopp, Ulrike; Kass, Gary; Leeder, Tim; Lickorish, Fiona A.; Lueshi, Leila M.; Magee, Chris; Mata, Tiago; McBride, Tony; McCarthy, Natasha; Mercer, Alan; Neilson, Ross; Ouchikh, Jackie; Oughton, Edward J.; Oxenham, David; Pallett, Helen; Palmer, James; Patmore, Jeff; Petts, Judith; Pinkerton, Jan; Ploszek, Richard; Pratt, Alan; Rocks, Sophie A.; Stansfield, Neil; Surkovic, Elizabeth; Tyler, Christopher P.; Watkinson, Andrew R.; Wentworth, Jonny; Willis, Rebecca; Wollner, Patrick K. A.; Worts, Kim; Sutherland, William J.

    2014-01-01

    Public policy requires public support, which in turn implies a need to enable the public not just to understand policy but also to be engaged in its development. Where complex science and technology issues are involved in policy making, this takes time, so it is important to identify emerging issues of this type and prepare engagement plans. In our horizon scanning exercise, we used a modified Delphi technique [1]. A wide group of people with interests in the science and policy interface (drawn from policy makers, policy adviser, practitioners, the private sector and academics) elicited a long list of emergent policy issues in which science and technology would feature strongly and which would also necessitate public engagement as policies are developed. This was then refined to a short list of top priorities for policy makers. Thirty issues were identified within broad areas of business and technology; energy and environment; government, politics and education; health, healthcare, population and aging; information, communication, infrastructure and transport; and public safety and national security. PMID:24879444

  10. Status of molten carbonate fuel cell technology development

    NASA Astrophysics Data System (ADS)

    Parsons, E. L., Jr.; Williams, M. C.; George, T. J.

    The MCFC technology has been identified by the DOE as a promising product for commercialization. Development of the MCFC technology supports the National Energy Strategy. Review of the status of the MCFC technology indicates that the MCFC technology developers are making rapid and significant progress. Manufacturing facility development and extensive testing is occurring. Improvements in performance (power density), lower costs, improved packaging, and scale up to full height are planned. MCFC developers need to continue to be responsive to end-users in potential markets. It will be market demands for the correct product definition which will ultimately determine the character of MCFC power plants. There is a need for continued MCFC product improvement and multiple product development tests.

  11. SUPERFUND INNOVATIVE TECHNOLOGY EVALUATION PROGRAM - TECHNOLOGY PROFILES 4th Edition

    EPA Science Inventory

    The Superfund Innovative Technology Evaluation (SITE) Program evaluates new and promising treatment technologies for cleanup of hazardous waste sites. The program was created to encourage the development and routine use of innovative treatment technologies. As a result, the SI...

  12. Promising Practices: A Literature Review of Technology Use by Underserved Students

    ERIC Educational Resources Information Center

    Zielezinski, Molly B.; Darling-Hammond, Linda

    2016-01-01

    How can technologies and digital learning experiences be used to support underserved, under-resourced, and underprepared students? For many years, educators, researchers, and policy makers looking for strategies to close the achievement gap and improve student learning have sought solutions involving new uses of technology, especially for students…

  13. Meet the Promise of Content Standards: Tapping Technology to Enhance Professional Learning

    ERIC Educational Resources Information Center

    Killion, Joellen

    2013-01-01

    More stakeholders are turning to technology to advance the professional learning required to support new standards and evaluation systems. Yet how technology is used will determine its potential to influence educator practice and results for students. This brief outlines how technology can enhance professional learning, offers examples of how…

  14. Decision support for redesigning wastewater treatment technologies.

    PubMed

    McConville, Jennifer R; Künzle, Rahel; Messmer, Ulrike; Udert, Kai M; Larsen, Tove A

    2014-10-21

    This paper offers a methodology for structuring the design space for innovative process engineering technology development. The methodology is exemplified in the evaluation of a wide variety of treatment technologies for source-separated domestic wastewater within the scope of the Reinvent the Toilet Challenge. It offers a methodology for narrowing down the decision-making field based on a strict interpretation of treatment objectives for undiluted urine and dry feces and macroenvironmental factors (STEEPLED analysis) which influence decision criteria. Such an evaluation identifies promising paths for technology development such as focusing on space-saving processes or the need for more innovation in low-cost, energy-efficient urine treatment methods. Critical macroenvironmental factors, such as housing density, transportation infrastructure, and climate conditions were found to affect technology decisions regarding reactor volume, weight of outputs, energy consumption, atmospheric emissions, investment cost, and net revenue. The analysis also identified a number of qualitative factors that should be carefully weighed when pursuing technology development; such as availability of O&M resources, health and safety goals, and other ethical issues. Use of this methodology allows for coevolution of innovative technology within context constraints; however, for full-scale technology choices in the field, only very mature technologies can be evaluated.

  15. Human Exploration and Avionic Technology Challenges

    NASA Technical Reports Server (NTRS)

    Benjamin, Andrew L.

    2005-01-01

    For this workshop, I will identify critical avionic gaps, enabling technologies, high-pay off investment opportunities, promising capabilities, and space applications for human lunar and Mars exploration. Key technology disciplines encompass fault tolerance, miniaturized instrumentation sensors, MEMS-based guidance, navigation, and controls, surface communication networks, and rendezvous and docking. Furthermore, I will share bottom-up strategic planning relevant to manned mission -driven needs. Blending research expertise, facilities, and personnel with internal NASA is vital to stimulating collaborative technology solutions that achieve NASA grand vision. Retaining JSC expertise in unique and critical areas is paramount to our long-term success. Civil servants will maintain key roles in setting technology agenda, ensuring quality results, and integrating technologies into avionic systems and manned missions. Finally, I will present to NASA, academia, and the aerospace community some on -going and future advanced avionic technology programs and activities that are relevant to our mission goals and objectives.

  16. The SUPERFUND INNOVATIVE TECHNOLOGY EVALUATION program - Technology Profiles

    EPA Science Inventory

    The Superfund Innovative Technology Evaluation (SITE) program was created to evaluate new and promising treatment technologies for cleanup at hazardous waste sites. The mission of the SITE program is to encourage the development and routine use of innovative treatment technologie...

  17. HTA and its legal issues: a framework for identifying legal issues in health technology assessment.

    PubMed

    Widrig, Daniel; Tag, Brigitte

    2014-12-01

    Legal analysis can highlight important issues that are relevant when deciding whether a medical technology should be implemented or reimbursed. Literature and studies show that even though the law is an acknowledged part of health technology assessment (HTA), legal issues are rarely considered in practice. One reason for this may be the lack of knowledge about the diversity of legal issues that are relevant for HTA. Therefore, this contribution aims primarily to identify and then explain the relevant legal issues in HTA. This study offers a framework for identifying the legal issues in HTAs in different jurisdictions and provides a basis for further research. After extensive literature search, the authors review Swiss health law to identify legal issues that are relevant to HTA. The authors then categorize these legal issues using a framework with an inside and outside perspective. Finally, they explain a selection of these legal issues with several examples. This study reveals numerous legal issues that are relevant for HTA and underlines the necessity of incorporating legal analysis in HTAs. The suggested perspectival framework in this study provides a basis to structure the legal analysis. The identified legal issues are relevant in other countries and the perspectival framework is transferable to other jurisdictions. The article underlines the importance of in-depth discussion about the role of law in HTA. It provides a structured overview of the legal issues in HTA and suggests a development of more concrete instruments toward a standardized legal technology assessment.

  18. Computer Technology Integration and Student Learning: Barriers and Promise

    ERIC Educational Resources Information Center

    Keengwe, Jared; Onchwari, Grace; Wachira, Patrick

    2008-01-01

    Political and institutional support has enabled many institutions of learning to spend millions of dollars to acquire educational computing tools (Ficklen and Muscara, "Am Educ" 25(3):22-29, 2001) that have not been effectively integrated into the curriculum. While access to educational technology tools has remarkably improved in most schools,…

  19. Hot Technologies for K-12 Schools: The 2005 Guide for Technology Decision Makers. COSN's Emerging Technologies Series

    ERIC Educational Resources Information Center

    Vockley, Martha, Ed.

    2004-01-01

    As technology companies introduce innovative products and services for the education market, school districts have the opportunity to invest in technologies designed to improve instruction and operations--from teaching, learning and assessments to organizational efficiency. Perhaps the greatest promise of anticipated technologies is their…

  20. AMLCD cockpit: promise and payoffs

    NASA Astrophysics Data System (ADS)

    Snow, Michael P.; Jackson, Timothy W.; Meyer, Frederick M.; Reising, John M.; Hopper, Darrel G.

    1999-08-01

    The active matrix liquid crystal display (AMLCD) has become the preferred flight instrument technology in avionics multifunction display applications. Current bubble canopy fighter cockpit applications involve sizes up to 7.8 X 7.8 in. active display. Dual use avionics versions of AMLCD technology are now as large as 6.7 X 6.7 in. active display area in the ARINC D sized color multifunction display (MFD). This is the standard instrument in all new Boeing transport aircraft and is being retrofitted into the C-17A. A special design of the ARINC D instrument is used in the Space Shuttle cockpit upgrade. Larger sizes of AMLCD were desired when decisions were made in the early 1990s for the F-22. Commercial AMLCD technology has now produced monitors at 1280 X 1024 resolution (1.3 megapixels) in sizes of 16 to 21 in. diagonal. Each of these larger AMLCDs has more information carrying capacity than the entire F-22A cockpit instrument panel shipset, comprising six separate smaller AMLCDs (1.2 megapixels total). The larger AMLCDs are being integrated into airborne mission crewstations for use in dim ambient lighting conditions. It is now time to identify and address the technology challenges of upgrading these larger AMLCDs for sunlight readable application and of developing concepts for their integration into advanced bubble canopy fighter cockpits. The overall goals are to significantly increase the informational carrying capacity to bring both sensor and information fusion into the cockpit and, thereby, to enable a significant increase in warfighter situational awareness and effectiveness. A research cockpit was built using specialized versions of the IBM 16.1 in and two smaller 10 in. AMLCDs to examine human factors and display design issues associated with these next-generation AMLCD cockpit displays. This cockpit was later upgraded to allow greater reconfigurability and flexibility in the display hardware used to conduct part- task mission simulations. The objective

  1. NASA's progress in nuclear electric propulsion technology

    NASA Technical Reports Server (NTRS)

    Stone, James R.; Doherty, Michael P.; Peecook, Keith M.

    1993-01-01

    The National Aeronautics and Space Administration (NASA) has established a requirement for Nuclear Electric Propulsion (NEP) technology for robotic planetary science mission applications with potential future evolution to systems for piloted Mars vehicles. To advance the readiness of NEP for these challenging missions, a near-term flight demonstration on a meaningful robotic science mission is very desirable. The requirements for both near-term and outer planet science missions are briefly reviewed, and the near-term baseline system established under a recent study jointly conducted by the Lewis Research Center (LeRC) and the Jet Propulsion Laboratory (JPL) is described. Technology issues are identified where work is needed to establish the technology for the baseline system, and technology opportunities which could provide improvement beyond baseline capabilities are discussed. Finally, the plan to develop this promising technology is presented and discussed.

  2. Quantitative Analysis of Technological Innovation in Knee Arthroplasty: Using Patent and Publication Metrics to Identify Developments and Trends.

    PubMed

    Dalton, David M; Burke, Thomas P; Kelly, Enda G; Curtin, Paul D

    2016-06-01

    Surgery is in a constant continuum of innovation with refinement of technique and instrumentation. Arthroplasty surgery potentially represents an area with highly innovative process. This study highlights key area of innovation in knee arthroplasty over the past 35 years using patent and publication metrics. Growth rates and patterns are analyzed. Patents are correlated to publications as a measure of scientific support. Electronic patent and publication databases were searched over the interval 1980-2014 for "knee arthroplasty" OR "knee replacement." The resulting patent codes were allocated into technology clusters. Citation analysis was performed to identify any important developments missed on initial analysis. The technology clusters identified were further analyzed, individual repeat searches performed, and growth curves plotted. The initial search revealed 3574 patents and 16,552 publications. The largest technology clusters identified were Unicompartmental, Patient-Specific Instrumentation (PSI), Navigation, and Robotic knee arthroplasties. The growth in patent activity correlated strongly with publication activity (Pearson correlation value 0.892, P < .01), but was growing at a faster rate suggesting a decline in vigilance. PSI, objectively the fastest growing technology in the last 5 years, is currently in a period of exponential growth that began a decade ago. Established technologies in the study have double s-shaped patent curves. Identifying trends in emerging technologies is possible using patent metrics and is useful information for training and regulatory bodies. The decline in ratio of publications to patents and the uninterrupted growth of PSI are developments that may warrant further investigation. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. Promise of new imaging technologies for assessing ovarian function.

    PubMed

    Singh, Jaswant; Adams, Gregg P; Pierson, Roger A

    2003-10-15

    Advancements in imaging technologies over the last two decades have ushered a quiet revolution in research approaches to the study of ovarian structure and function. The most significant changes in our understanding of the ovary have resulted from the use of ultrasonography which has enabled sequential analyses in live animals. Computer-assisted image analysis and mathematical modeling of the dynamic changes within the ovary has permitted exciting new avenues of research with readily quantifiable endpoints. Spectral, color-flow and power Doppler imaging now facilitate physiologic interpretations of vascular dynamics over time. Similarly, magnetic resonance imaging (MRI) is emerging as a research tool in ovarian imaging. New technologies, such as three-dimensional ultrasonography and MRI, ultrasound-based biomicroscopy and synchrotron-based techniques each have the potential to enhance our real-time picture of ovarian function to the near-cellular level. Collectively, information available in ultrasonography, MRI, computer-assisted image analysis and mathematical modeling heralds a new era in our understanding of the basic processes of female and male reproduction.

  4. Promising Technologies of Mining and Processing of Solid Minerals

    NASA Astrophysics Data System (ADS)

    Shabaev, Sergey; Ivanov, Seregey; Vakhianov, Evgeniy

    2017-11-01

    The continuing growth in mineral extraction entails an increase in industrial waste, which in turn has a negative impact on the environment. Rubber-tired vehicles, in which the tires wear colossally, is mainly used as a transport for loading, unloading, transportation and other types of work in the extraction of solid minerals. The used tires are not disposed in any way, but are stored in special areas where harmful toxic substances are emitted under the influence of ultraviolet rays. Therefore, a decision was made to find a method for utilization and rational use of industrial waste in the road construction sector. The operating temperature of composite rubber-bituminous binders based on rubber crumb from the used automobile tires is estimated in this paper, which is necessary for assigning technological parameters of production and laying of asphalt-concrete mixtures produced on their basis. It is established that composite rubber-bituminous binders based on rubber chips from the used automobile tires, produced according to the two-stage technology, have the same viscosity as the original petroleum bitumen, at a temperature increased by 20°C.

  5. Mini-ISES identifies promising carbafructopyranose-based salens for asymmetric catalysis: Tuning ligand shape via the anomeric effect

    PubMed Central

    Karukurichi, Kannan R.; Fei, Xiang; Swyka, Robert A.; Broussy, Sylvain; Shen, Weijun; Dey, Sangeeta; Roy, Sandip K.; Berkowitz, David B.

    2015-01-01

    This study introduces new methods of screening for and tuning chiral space and in so doing identifies a promising set of chiral ligands for asymmetric synthesis. The carbafructopyranosyl-1,2-diamine(s) and salens constructed therefrom are particularly compelling. It is shown that by removing the native anomeric effect in this ligand family, one can tune chiral ligand shape and improve chiral bias. This concept is demonstrated by a combination of (i) x-ray crystallographic structure determination, (ii) assessment of catalytic performance, and (iii) consideration of the anomeric effect and its underlying dipolar basis. The title ligands were identified by a new mini version of the in situ enzymatic screening (ISES) procedure through which catalyst-ligand combinations are screened in parallel, and information on relative rate and enantioselectivity is obtained in real time, without the need to quench reactions or draw aliquots. Mini-ISES brings the technique into the nanomole regime (200 to 350 nmol catalyst/20 μl organic volume) commensurate with emerging trends in reaction development/process chemistry. The best-performing β-d-carbafructopyranosyl-1,2-diamine–derived salen ligand discovered here outperforms the best known organometallic and enzymatic catalysts for the hydrolytic kinetic resolution of 3-phenylpropylene oxide, one of several substrates examined for which the ligand is “matched.” This ligand scaffold defines a new swath of chiral space, and anomeric effect tunability defines a new concept in shaping that chiral space. Both this ligand set and the anomeric shape-tuning concept are expected to find broad application, given the value of chiral 1,2-diamines and salens constructed from these in asymmetric catalysis. PMID:26501130

  6. Realising the Promise of Cancer Predisposition Genes

    PubMed Central

    Rahman, Nazneen

    2016-01-01

    Genes in which germline mutations confer high or moderate increased risks of cancer are called cancer predisposition genes (CPG). Over 100 CPGs have been identified providing important scientific insights in many areas, particularly mechanisms of cancer causation. Moreover, clinical utilisation of CPGs has had substantial impact in diagnosis, optimised management and prevention of cancer. The recent transformative advances in DNA sequencing bring the promise of many more CPG discoveries and greater, broader clinical applications. However, there is also considerable potential for incorrect inferences and inappropriate clinical applications. Realising the promise of cancer predisposition genes for science and medicine will thus require careful navigation. PMID:24429628

  7. Profiles of Selected Promising Professional Development Initiatives.

    ERIC Educational Resources Information Center

    Cohen, Carol; Gerber, Peter; Handley, Claire; Kronley, Robert; Parry, Megan

    In 2000, the Finance Project received a planning grant to launch a new initiative on financing professional development in education. This report represents efforts to identify and develop a database on promising new approaches to professional development in education, profiling 16 initiatives recommended by knowledge experts and representing a…

  8. Using Active Learning to Identify Health Information Technology Related Patient Safety Events.

    PubMed

    Fong, Allan; Howe, Jessica L; Adams, Katharine T; Ratwani, Raj M

    2017-01-18

    The widespread adoption of health information technology (HIT) has led to new patient safety hazards that are often difficult to identify. Patient safety event reports, which are self-reported descriptions of safety hazards, provide one view of potential HIT-related safety events. However, identifying HIT-related reports can be challenging as they are often categorized under other more predominate clinical categories. This challenge of identifying HIT-related reports is exacerbated by the increasing number and complexity of reports which pose challenges to human annotators that must manually review reports. In this paper, we apply active learning techniques to support classification of patient safety event reports as HIT-related. We evaluated different strategies and demonstrated a 30% increase in average precision of a confirmatory sampling strategy over a baseline no active learning approach after 10 learning iterations.

  9. Aptamer-Based Analysis: A Promising Alternative for Food Safety Control

    PubMed Central

    Amaya-González, Sonia; de-los-Santos-Álvarez, Noemí; Miranda-Ordieres, Arturo J.; Lobo-Castañón, Maria Jesús

    2013-01-01

    Ensuring food safety is nowadays a top priority of authorities and professional players in the food supply chain. One of the key challenges to determine the safety of food and guarantee a high level of consumer protection is the availability of fast, sensitive and reliable analytical methods to identify specific hazards associated to food before they become a health problem. The limitations of existing methods have encouraged the development of new technologies, among them biosensors. Success in biosensor design depends largely on the development of novel receptors with enhanced affinity to the target, while being stable and economical. Aptamers fulfill these characteristics, and thus have surfaced as promising alternatives to natural receptors. This Review describes analytical strategies developed so far using aptamers for the control of pathogens, allergens, adulterants, toxins and other forbidden contaminants to ensure food safety. The main progresses to date are presented, highlighting potential prospects for the future. PMID:24287543

  10. Considerations for Realizing the Promise of Educational Gaming Technology

    ERIC Educational Resources Information Center

    Nelson, Nancy J.; Fien, Hank; Doabler, Christian T.; Clarke, Ben

    2016-01-01

    One can barely keep up with the pace at which new educational games and apps are being introduced and digested in the market. With so many choices available, how do schools and teachers decide what to use? How do they have confidence their choices will result in desired outcomes? Education technology offers a number of potential benefits that can…

  11. Technology for Children With Brain Injury and Motor Disability: Executive Summary From Research Summit IV.

    PubMed

    Christy, Jennifer B; Lobo, Michele A; Bjornson, Kristie; Dusing, Stacey C; Field-Fote, Edelle; Gannotti, Mary; Heathcock, Jill C; OʼNeil, Margaret E; Rimmer, James H

    Advances in technology show promise as tools to optimize functional mobility, independence, and participation in infants and children with motor disability due to brain injury. Although technologies are often used in adult rehabilitation, these have not been widely applied to rehabilitation of infants and children. In October 2015, the Academy of Pediatric Physical Therapy sponsored Research Summit IV, "Innovations in Technology for Children With Brain Insults: Maximizing Outcomes." The summit included pediatric physical therapist researchers, experts from other scientific fields, funding agencies, and consumers. Participants identified challenges in implementing technology in pediatric rehabilitation including accessibility, affordability, managing large data sets, and identifying relevant data elements. Participants identified 4 key areas for technology development: to determine (1) thresholds for learning, (2) appropriate transfer to independence, (3) optimal measurement of subtle changes, and (4) how to adapt to growth and changing abilities.

  12. Effect of Induced Pluripotent Stem Cell Technology in Blood Banking

    PubMed Central

    Focosi, Daniele

    2016-01-01

    Summary Population aging has imposed cost-effective alternatives to blood donations. Artificial blood is still at the preliminary stages of development, and the need for viable cells seems unsurmountable. Because large numbers of viable cells must be promptly available for clinical use, stem cell technologies, expansion, and banking represent ideal tools to ensure a regular supply. Provided key donors can be identified, induced pluripotent stem cell (iPSC) technology could pave the way to a new era in transfusion medicine, just as it is already doing in many other fields of medicine. The present review summarizes the current state of research on iPSC technology in the field of blood banking, highlighting hurdles, and promises. Significance The aging population in Western countries is causing a progressive reduction of blood donors and a constant increase of blood recipients. Because blood is the main therapeutic option to treat acute hemorrhage, cost-effective alternatives to blood donations are being actively investigated. The enormous replication capability of induced pluripotent stem cells and their promising results in many other fields of medicine could be an apt solution to produce the large numbers of viable cells required in transfusion and usher in a new era in transfusion medicine. The present report describes the potentiality, technological hurdles, and promises of induced pluripotent stem cells to generate red blood cells by redifferentiation. PMID:26819256

  13. SUPERFUND INNOVATIVE TECHNOLOGY EVALUATION PROGRAM TECHNOLOGY PROFILES: SIXTH EDITION

    EPA Science Inventory

    The Superfund Innovative Technology Evaluation (SITE) Program evaluates new and promising treatment and monitoring and measurement technologies for cleanup of hazardous waste sites. The program was created to encourage the development and routine use of innovative treatment techn...

  14. SUPERFUND INNOVATIVE TECHNOLOGY EVALUATION PROGRAM - TECHNOLOGY PROFILES - SEVENTH EDITION

    EPA Science Inventory

    The Superfund Innovative Technology Evaluation (SITE) Program evaluates new and promising treatment and monitoring and measurement technologies for cleanup of hazardous waste sites. The program was created to encourage the development and routine use of innovative treatment techn...

  15. Electron-processing technology: A promising application for the viscose industry

    NASA Astrophysics Data System (ADS)

    Stepanik, T. M.; Rajagopal, S.; Ewing, D.; Whitehouse, R.

    1998-06-01

    In marketing its IMPELA ® line of high power, high-throughput industrial accelerators, Atomic Energy of Canada Limited (AECL) is working with viscose (rayon) companies world-wide to integrate electron-processing technology as part of the viscose manufacturing process. The viscose industry converts cellulose wood pulp into products such as staple fiber, filament, cord, film, packaging, and non-edible sausage casings. This multibillion dollar industry is currently suffering from high production costs, and is facing increasingly stringent environmental regulations. The use of electron-treated pulp can significantly lower production costs and can provide equally significant environmental benefits. This paper describes our current understanding of the benefits of using electron-treated pulp in this process, and AECL's efforts in developing this technology.

  16. Bioactive natural products in cancer prevention and therapy: Progress and promise.

    PubMed

    Bishayee, Anupam; Sethi, Gautam

    2016-10-01

    Natural products represent a rich source for the discovery and development of cancer preventive and anticancer drugs. Nearly, 80% of all drugs approved by the United States Food and Drug Administration during the last three decades for cancer therapy are either natural products per se or are based thereon, or mimicked natural products in one form or another. With the advent and refinement of new technologies, such as genetic techniques for production of secondary plant metabolites, combinatorial synthesis and high-throughput screening, it is expected that novel compounds from natural sources, including medicinal plants, would be identified and developed as safe and effective chemopreventive and anticancer drugs. Numerous bioactive natural compounds have been shown to be useful in prevention and therapy of cancer by targeting various signaling molecules and pathways. Extensive literature underscores the anticancer and chemopreventive activity of a plethora of naturally occurring agents, including phytochemicals. Several of these molecules have been tested in clinical trials and some of them have shown promise in combination therapy when administered along with standard chemotherapeutic agents. Thus, accelerated chemopreventive and chemotherapeutic drug development from natural sources is of great importance. In this special theme issue, contributions from eminent scientists and scholars around the world presented critical analysis of the current progress and promise of natural bioactive constituents in cancer prevention and therapy. Copyright © 2016 Elsevier Ltd. All rights reserved.

  17. Realization of a universal patient identifier for electronic medical records through biometric technology.

    PubMed

    Leonard, D C; Pons, Alexander P; Asfour, Shihab S

    2009-07-01

    The technology exists for the migration of healthcare data from its archaic paper-based system to an electronic one, and, once in digital form, to be transported anywhere in the world in a matter of seconds. The advent of universally accessible healthcare data has benefited all participants, but one of the outstanding problems that must be addressed is how the creation of a standardized nationwide electronic healthcare record system in the United States would uniquely identify and match a composite of an individual's recorded healthcare information to an identified individual patients out of approximately 300 million people to a 1:1 match. To date, a few solutions to this problem have been proposed that are limited in their effectiveness. We propose the use of biometric technology within our fingerprint, iris, retina scan, and DNA (FIRD) framework, which is a multiphase system whose primary phase is a multilayer consisting of these four types of biometric identifiers: 1) fingerprint; 2) iris; 3) retina scan; and 4) DNA. In addition, it also consists of additional phases of integration, consolidation, and data discrepancy functions to solve the unique association of a patient to their medical data distinctively. This would allow a patient to have real-time access to all of their recorded healthcare information electronically whenever it is necessary, securely with minimal effort, greater effectiveness, and ease.

  18. Identifying Areas of Tension in the Field of Technology-Enhanced Learning: Results of an International Delphi Study

    ERIC Educational Resources Information Center

    Plesch, Christine; Kaendler, Celia; Rummel, Nikol; Wiedmann, Michael; Spada, Hans

    2013-01-01

    Despite steady progress in research in technology-enhanced learning (TEL), the translation of research findings and technology into educational practices falls short of expectations. We present five Areas of Tension which were identified and evaluated in an international Delphi study on TEL. These tensions might impede a more comprehensive…

  19. Technology needs for high-speed rotorcraft, volume 1

    NASA Technical Reports Server (NTRS)

    Wilkerson, J. B.; Schneider, J. J.; Bartie, K. M.

    1991-01-01

    High-speed rotorcraft concepts and the technology needed to extend rotorcraft cruise speeds up to 450 knots (while retaining the helicopter attributes of low downwash velocities) were identified. Task I identified 20 concepts with high-speed potential. These concepts were qualitatively evaluated to determine the five most promising ones. These five concepts were designed with optimum wing loading and disk loading to a common NASA-defined military transport mission. The optimum designs were quantitatively compared against 11 key criteria and ranked accordingly. The two highest ranking concepts were selected for the further study.

  20. Polymer microarray technology for stem cell engineering

    PubMed Central

    Coyle, Robert; Jia, Jia; Mei, Ying

    2015-01-01

    Stem cells hold remarkable promise for applications in tissue engineering and disease modeling. During the past decade, significant progress has been made in developing soluble factors (e.g., small molecules and growth factors) to direct stem cells into a desired phenotype. However, the current lack of suitable synthetic materials to regulate stem cell activity has limited the realization of the enormous potential of stem cells. This can be attributed to a large number of materials properties (e.g., chemical structures and physical properties of materials) that can affect stem cell fate. This makes it challenging to design biomaterials to direct stem cell behavior. To address this, polymer microarray technology has been developed to rapidly identify materials for a variety of stem cell applications. In this article, we summarize recent developments in polymer array technology and their applications in stem cell engineering. Statement of significance Stem cells hold remarkable promise for applications in tissue engineering and disease modeling. In the last decade, significant progress has been made in developing chemically defined media to direct stem cells into a desired phenotype. However, the current lack of the suitable synthetic materials to regulate stem cell activities has been limiting the realization of the potential of stem cells. This can be attributed to the number of variables in material properties (e.g., chemical structures and physical properties) that can affect stem cells. Polymer microarray technology has shown to be a powerful tool to rapidly identify materials for a variety of stem cell applications. Here we summarize recent developments in polymer array technology and their applications in stem cell engineering. PMID:26497624

  1. Pediatric Multiple Organ Dysfunction Syndrome: Promising Therapies.

    PubMed

    Doctor, Allan; Zimmerman, Jerry; Agus, Michael; Rajasekaran, Surender; Bubeck Wardenburg, Juliane; Fortenberry, James; Zajicek, Anne; Mairson, Emma; Typpo, Katri

    2017-03-01

    To describe the state of the science, identify knowledge gaps, and offer potential future research questions regarding promising therapies for children with multiple organ dysfunction syndrome presented during the Eunice Kennedy Shriver National Institute of Child Health and Human Development Workshop on Pediatric Multiple Organ Dysfunction Syndrome (March 26-27, 2015). Literature review, research data, and expert opinion. Not applicable. Moderated by an expert from the field, issues relevant to the association of multiple organ dysfunction syndrome with a variety of conditions were presented, discussed, and debated with a focus on identifying knowledge gaps and research priorities. Summary of presentations and discussion supported and supplemented by relevant literature. Among critically ill children, multiple organ dysfunction syndrome is relatively common and associated with significant morbidity and mortality. For outcomes to improve, effective therapies aimed at preventing and treating this condition must be discovered and rigorously evaluated. In this article, a number of potential opportunities to enhance current care are highlighted including the need for a better understanding of the pharmacokinetics and pharmacodynamics of medications, the effect of early and optimized nutrition, and the impact of effective glucose control in the setting of multiple organ dysfunction syndrome. Additionally, a handful of the promising therapies either currently being implemented or developed are described. These include extracorporeal therapies, anticytokine therapies, antitoxin treatments, antioxidant approaches, and multiple forms of exogenous steroids. For the field to advance, promising therapies and other therapies must be assessed in rigorous manner and implemented accordingly.

  2. Technological advances in the treatment of trauma: a review of promising practices.

    PubMed

    Paul, Lisa A; Hassija, Christina M; Clapp, Joshua D

    2012-11-01

    Given the availability of empirically supported practices for addressing posttraumatic stress disorder and other forms of trauma-related distress, the development and implementation of new technology to deliver these treatments is exciting. Technological innovations in this literature aim to expand availability of empirically based intervention, increase treatment adherence and acceptability, and overcome barriers commonly encountered with conventional trauma-focused treatment. Much of the current research on these technological developments consists of brief reviews and case studies of the separate therapy modalities. Although this work serves to document the appeal and utility of these innovations, it does not provide comprehensive information about the host of options available. To that end, the three general categories of technological advances in trauma therapy (i.e., videoconferencing, e-Health, virtual reality) are reviewed here, including information regarding their empirical support and suggestions for future research and clinical practice.

  3. Workforce 2000 and the Mildly Handicapped. Identifying Emerging Issues and Trends in Technology for Special Education.

    ERIC Educational Resources Information Center

    Woodward, John

    As part of a 3-year study to identify emerging issues and trends in technology for special education, this paper explores the changing nature of the workforce in relation to concurrent changes in education services for students with mild disabilities. Current trends are identified and projections for the next decade are offered, which include the…

  4. The Promise of MIDI Technology: A Reflection on Musical Intelligence.

    ERIC Educational Resources Information Center

    Ohler, Jason

    1998-01-01

    Describes MIDI (Musical Instrument Digital Interface) technology and music education; provides information on conducting a MIDI workshop for all ages; and offers guidelines for creating a MIDI workstation for the classroom. Hardware and software vendor contact information is provided. (PEN)

  5. Mitochondrion: A Promising Target for Nanoparticle-Based Vaccine Delivery Systems

    PubMed Central

    Wen, Ru; Umeano, Afoma C.; Francis, Lily; Sharma, Nivita; Tundup, Smanla; Dhar, Shanta

    2016-01-01

    Vaccination is one of the most popular technologies in disease prevention and eradication. It is promising to improve immunization efficiency by using vectors and/or adjuvant delivery systems. Nanoparticle (NP)-based delivery systems have attracted increasing interest due to enhancement of antigen uptake via prevention of vaccine degradation in the biological environment and the intrinsic immune-stimulatory properties of the materials. Mitochondria play paramount roles in cell life and death and are promising targets for vaccine delivery systems to effectively induce immune responses. In this review, we focus on NPs-based delivery systems with surfaces that can be manipulated by using mitochondria targeting moieties for intervention in health and disease. PMID:27258316

  6. Technological Advances in the Treatment of Trauma: A Review of Promising Practices

    ERIC Educational Resources Information Center

    Paul, Lisa A.; Hassija, Christina M.; Clapp, Joshua D.

    2012-01-01

    Given the availability of empirically supported practices for addressing posttraumatic stress disorder and other forms of trauma-related distress, the development and implementation of new technology to deliver these treatments is exciting. Technological innovations in this literature aim to expand availability of empirically based intervention,…

  7. The promise of e-health--a Canadian perspective.

    PubMed

    Alvarez, Richard C

    2004-01-01

    Canadians value their health care system above any other social programme. Canada's system of health care faces significant financial and population pressures, relating to cost, access, quality, accountability, and the intergration of information and communication technologies (ICTs). The health-system also faces certain unique challenges that include care delivery within a highly decentralised system of financing and accountability, and care delivery to a significant portion of the population sparsely distributed across a land mass of 10 million square kilometres, in areas of extreme climatic conditions. All of these challenges are significant catalysts in the development of technologies that aim to significantly mitigate or eliminate these selfsame challenges. The system is undergoing widespread review, nationally and within each province and territory, where the bulk of care provision is financed and managed. The challenges are being addressed by national, regional and provincial initiatives in the public, private and not-for-profit sectors. The promise of e-health lies in the manner and degree to which it can mitigate or resolve these challenges to the health system and build on advancements in ICTs supporting the development of a health infostructure. Canada is actively developing and implementing technological solutions to deliver health information and health care services across the country. These solutions, while exciting and promising, also present new challenges, particularly in regard to acceptable standards, choice of technologies, overcoming traditional jurisdictional boundaries, up-front investment, and privacy and confidentiality. Many organizations and governments are working to address these challenges. Canada Health Infoway, a not-for-profit corporation, was founded by the first ministers in 2001 to accelerate the establishment of an interoperable, pan-Canadian electronic health record. It works with partners in the federal, provincial and

  8. Propulsion system study for Small Transport Aircraft Technology (STAT)

    NASA Technical Reports Server (NTRS)

    Smith, C. E.; Hirschkron, R.; Warren, R. E.

    1981-01-01

    Propulsion system technologies applicable to the generation of commuter airline aircraft expected to enter service in the 1990's are identified and evaluated in terms of their impact on aircraft operating economics and fuel consumption. The most promising technologies in the areas of engine, propeller, gearbox, and nacelle design are recommended for future research. Each item under consideration is evaluated relative to a modern baseline engine, the General Electric CT7-5, in a current technology aircraft flying a fixed range and payload. The analysis is presented for two aircraft sizes (30 and 50 passenger), over a range of mission lengths (100 to 1100 km) and fuel costs ($264 to $396 per cu m).

  9. Do promises matter? An exploration of the role of promises in psychological contract breach.

    PubMed

    Montes, Samantha D; Zweig, David

    2009-09-01

    Promises are positioned centrally in the study of psychological contract breach and are argued to distinguish psychological contracts from related constructs, such as employee expectations. However, because the effects of promises and delivered inducements are confounded in most research, the role of promises in perceptions of, and reactions to, breach remains unclear. If promises are not an important determinant of employee perceptions, emotions, and behavioral intentions, this would suggest that the psychological contract breach construct might lack utility. To assess the unique role of promises, the authors manipulated promises and delivered inducements separately in hypothetical scenarios in Studies 1 (558 undergraduates) and 2 (441 employees), and they measured them separately (longitudinally) in Study 3 (383 employees). The authors' results indicate that breach perceptions do not represent a discrepancy between what employees believe they were promised and were given. In fact, breach perceptions can exist in the absence of promises. Further, promises play a negligible role in predicting feelings of violation and behavioral intentions. Contrary to the extant literature, the authors' findings suggest that promises may matter little; employees are concerned primarily with what the organization delivers.

  10. Innovation and evaluation: taming and unleashing telecare technology.

    PubMed

    Pols, Jeannette; Willems, Dick

    2011-03-01

    Telecare is advocated in most European countries with great, if not grandiose, promises: improving healthcare, lowering costs, solving workforce shortage. This paper does not so much question these specific promises, but rather the 'register of promising' as such, by comparing the promises with actual processes of incorporating technologies in healthcare practices. The case we study is the use of webcams in follow-up care from a Dutch rehabilitation clinic for people with severe chronic obstructive pulmonary disease (COPD). This process shows many changes and contingencies, and corresponding shifts in goals and aims. The conclusion is that when innovative technologies such as telecare are actually put to work, 'the same' technology will perform differently. In order to function at all, technology has to be tamed, it has to be tinkered with to fit the practices of the users. The technology, however, is not meekly put to use (tamed), but is unleashed as well, affecting care practices in unforeseen ways. The untenability of pre-given promises and the fluidity of locally evolving goals has important implications for the way in which innovations are promoted, as well as for the way innovative technologies may be evaluated. © 2010 The Authors. Sociology of Health & Illness © 2010 Foundation for the Sociology of Health & Illness/Blackwell Publishing Ltd.

  11. Promising Practices in Drug Treatment: Findings from Europe

    ERIC Educational Resources Information Center

    Nemes, Susanna; Libretto, Salvatore; Skinstad, Anne Helene; Garrett, Gerald; Hoffman, Jeffrey A.

    2005-01-01

    In a study to evaluate the drug treatment and aftercare efforts sponsored by the State Department's International Narcotics and Law Enforcement Affairs Bureau, residential Therapeutic Community (TC) treatment programs in four European countries-Poland, Spain, Slovenia, and Italy-were examined to identify promising practices and to assess lessons…

  12. Improving math and science education in charter secondary schools through the use of technology

    NASA Astrophysics Data System (ADS)

    Ojose, Bobby

    This study was conducted to examine the promising practices of using technology in teaching math and science in charter schools in California. The study was conducted under the auspices of the Center for Educational Governance (CEG) which hopes to compile the promising practices into an Internet-based compendium to be replicated by others. The research employed an in-depth qualitative case study method. It was conducted in two secondary schools in different school districts in the state of California over a two-month period. The main participants were principals, lead teachers, teachers, and support staff. Interviews, observations, and archival documents were the main data collection tools. Face to face interviews were conducted with the principals, lead teachers of technology, teachers, and a support staff (Network Administrator). Technology lab and professional development activities were observed. Interviews were tape-recorded and transcribed. The study found that one school (MSA) has the promising practice of using technology to enhance the subject matter knowledge of students by using computers to further explore concepts already learned in the regular classroom. The other school (CART) has the promising practice of applying technology to real life situations as a teaching pedagogy. The result of these practices is the positive outcomes in the following areas: Increased student achievement in standardized teat scores, increased motivation, growth in mean GPA, less behavior problems from students, and improved school attendance by students. The implications for policy and practice include: Teachers having the knowledge of the benefits of constructive teaching in the classroom; principals understanding that professional development activities for technology integration will vary in complexities and depends on needs of teachers; policy makers identifying needs and establishing goals; and researchers conducting more qualitative studies to gather evidence to

  13. Chelation technology: a promising green approach for resource management and waste minimization.

    PubMed

    Chauhan, Garima; Pant, K K; Nigam, K D P

    2015-01-01

    Green chemical engineering recognises the concept of developing innovative environmentally benign technologies to protect human health and ecosystems. In order to explore this concept for minimizing industrial waste and for reducing the environmental impact of hazardous chemicals, new greener approaches need to be adopted for the extraction of heavy metals from industrial waste. In this review, a range of conventional processes and new green approaches employed for metal extraction are discussed in brief. Chelation technology, a modern research trend, has shown its potential to develop sustainable technology for metal extraction from various metal-contaminated sites. However, the interaction mechanism of ligands with metals and the ecotoxicological risk associated with the increased bioavailability of heavy metals due to the formation of metal-chelant complexes is still not sufficiently explicated in the literature. Therefore, a need was felt to provide a comprehensive state-of-the-art review of all aspects associated with chelation technology to promote this process as a green chemical engineering approach. This article elucidates the mechanism and thermodynamics associated with metal-ligand complexation in order to have a better understanding of the metal extraction process. The effects of various process parameters on the formation and stability of complexes have been elaborately discussed with respect to optimizing the chelation efficiency. The non-biodegradable attribute of ligands is another important aspect which is currently of concern. Therefore, biotechnological approaches and computational tools have been assessed in this review to illustrate the possibility of ligand degradation, which will help the readers to look for new environmentally safe mobilizing agents. In addition, emerging trends and opportunities in the field of chelation technology have been summarized and the diverse applicability of chelation technology in metal extraction from

  14. Technology Implementation in Education--Identifying Barriers to Fidelity

    ERIC Educational Resources Information Center

    Dennis, William J.; Johnson, Daniel L.; Monroe, Arla K.

    2012-01-01

    This report describes a problem-based learning project focused on determining the barriers to the implementation of technological innovations. Research findings offered evidence that properly executed technology implementation is an instructional variable related to student achievement; yet, school district leaders are faced with the problem of…

  15. Developing Mathematically Promising Students.

    ERIC Educational Resources Information Center

    Sheffield, Linda Jensen, Ed.

    This book, written on the recommendation of the Task Force on Mathematically Promising Students, investigates issues involving the development of promising mathematics students. Recommendations are made concerning topics such as the definition of promising students; the identification of such students; appropriate curriculum, instruction, and…

  16. Augmented Reality Based Doppler Lidar Data Visualization: Promises and Challenges

    NASA Astrophysics Data System (ADS)

    Cherukuru, N. W.; Calhoun, R.

    2016-06-01

    Augmented reality (AR) is a technology in which the enables the user to view virtual content as if it existed in real world. We are exploring the possibility of using this technology to view radial velocities or processed wind vectors from a Doppler wind lidar, thus giving the user an ability to see the wind in a literal sense. This approach could find possible applications in aviation safety, atmospheric data visualization as well as in weather education and public outreach. As a proof of concept, we used the lidar data from a recent field campaign and developed a smartphone application to view the lidar scan in augmented reality. In this paper, we give a brief methodology of this feasibility study, present the challenges and promises of using AR technology in conjunction with Doppler wind lidars.

  17. Optical Manufacturing and Testing Requirements Identified by the NASA Science Instruments, Observatories and Sensor Systems Technology Assessment

    NASA Technical Reports Server (NTRS)

    Stahl, H. Philip; Barney, Rich; Bauman, Jill; Feinberg, Lee; Mcleese, Dan; Singh, Upendra

    2011-01-01

    In August 2010, the NASA Office of Chief Technologist (OCT) commissioned an assessment of 15 different technology areas of importance to the future of NASA. Technology assessment #8 (TA8) was Science Instruments, Observatories and Sensor Systems (SIOSS). SIOSS assess the needs for optical technology ranging from detectors to lasers, x-ray mirrors to microwave antenna, in-situ spectrographs for on-surface planetary sample characterization to large space telescopes. The needs assessment looked across the entirety of NASA and not just the Science Mission Directorate. This paper reviews the optical manufacturing and testing technologies identified by SIOSS which require development in order to enable future NASA high priority missions.

  18. Identifying and Assessing Effective Mechanisms for Technology Transfer

    DTIC Science & Technology

    2007-03-01

    There is a distinct manner in which civilian technology is protected; even though secrecy is one option, as is the case with the Coca - Cola formula...done with the appropriate dedicated resources. They also placed heavy emphasis on acquiring early sponsorship for the technology and be able to set

  19. A Promising Development: "Promise" Scholarships Targeting Individual Communities Reduce Barriers to College Access--and Completion

    ERIC Educational Resources Information Center

    Pierce, Dennis

    2015-01-01

    This article discusses Promise Scholarships in community colleges and sources of funding. The following community colleges and their scholarships are mentioned in this article: (1) Oregon Promise, Oregon; (2) Ventura College Promise, California; (3) Kalamazoo Promise, Michigan; (4) Pittsburgh Promise, Pennsylvania; (5) SEED Scholarship, Delaware;…

  20. A Resource Guide Identifying Technology Tools for Schools. Appendix

    ERIC Educational Resources Information Center

    Fox, Christine; Jones, Rachel

    2009-01-01

    SETDA and NASTID's "Technology Tools for Schools Resource Guide" provides definitions of key technology components and relevant examples, where appropriate as a glossary for educators. The guide also presents essential implementation and infrastructure considerations that decision makers should think about when implementing technology in schools.…

  1. Adoption of Speech Recognition Technology in Community Healthcare Nursing.

    PubMed

    Al-Masslawi, Dawood; Block, Lori; Ronquillo, Charlene

    2016-01-01

    Adoption of new health information technology is shown to be challenging. However, the degree to which new technology will be adopted can be predicted by measures of usefulness and ease of use. In this work these key determining factors are focused on for design of a wound documentation tool. In the context of wound care at home, consistent with evidence in the literature from similar settings, use of Speech Recognition Technology (SRT) for patient documentation has shown promise. To achieve a user-centred design, the results from a conducted ethnographic fieldwork are used to inform SRT features; furthermore, exploratory prototyping is used to collect feedback about the wound documentation tool from home care nurses. During this study, measures developed for healthcare applications of the Technology Acceptance Model will be used, to identify SRT features that improve usefulness (e.g. increased accuracy, saving time) or ease of use (e.g. lowering mental/physical effort, easy to remember tasks). The identified features will be used to create a low fidelity prototype that will be evaluated in future experiments.

  2. Communication technologies to improve HPV vaccination initiation and completion: A systematic review.

    PubMed

    Francis, Diane B; Cates, Joan R; Wagner, Kyla P Garrett; Zola, Tracey; Fitter, Jenny E; Coyne-Beasley, Tamera

    2017-07-01

    This systematic review examines the effectiveness of communication technology interventions on HPV vaccination initiation and completion. A comprehensive search strategy was used to identify existing randomized controlled trials testing the impact of computer-, mobile- or internet-based interventions on receipt of any dose of the HPV vaccine. Twelve relevant studies were identified with a total of 38,945 participants. The interventions were delivered using several different methods, including electronic health record (i.e. recall/reminder) prompts, text messaging, automated phone calls, interactive computer videos, and email. Vaccine initiation and completion was greater for technology-based studies relative to their control conditions. There is evidence that interventions utilizing communication technologies as their sole or primary mode for HPV vaccination intervention delivery may increase vaccination coverage. Communication technologies hold much promise for the future of HPV vaccination efforts, especially initiatives in practice-based settings. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Transforming care delivery through health information technology.

    PubMed

    Wheatley, Benjamin

    2013-01-01

    The slow but progressive adoption of health information technology (IT) nationwide promises to usher in a new era in health care. Electronic health record systems provide a complete patient record at the point of care and can help to alleviate some of the challenges of a fragmented delivery system, such as drug-drug interactions. Moreover, health IT promotes evidence-based practice by identifying gaps in recommended treatment and providing clinical decision-support tools. In addition, the data collected through digital records can be used to monitor patient outcomes and identify potential improvements in care protocols. Kaiser Permanente continues to advance its capability in each of these areas.

  4. Technology, Teaching and Sanity.

    ERIC Educational Resources Information Center

    Coladarci, Arthur

    Despite recent advances in instructional technology, there still exist substantial gaps between technology's promise and its achievement. This situation is partly due to the fact that teachers who have a clear conception of the teaching-learning interaction are not involved in the implementation of technological innovations. Teachers and teacher…

  5. Simple indicator to identify the environmental soundness of growth of consumption and technology: "eco-velocity of consumption".

    PubMed

    Nansai, Keisuke; Kagawa, Shigemi; Suh, Sangwon; Inaba, Rokuta; Moriguchi, Yuichi

    2007-02-15

    Today's material welfare has been achieved at the expense of consumption of finite resources and generation of environmental burdens. Over the past few decades the volume of global consumption has grown dramatically, while at the same time technological advances have enabled products with greater efficiencies. These two directions of change, consumption growth and technological advance, are the foci of the present paper. Using quantitative measures for these two factors, we define a new indicator, "eco-velocity of consumption", analogous to velocity in physics. The indicator not only identifies the environmental soundness of consumption growth and technological advance but also indicates whether and to what extent our society is shifting toward sustainable consumption. This study demonstrates the practicability of the indicator through a case study in which we calculate the eco-velocities of Japanese household consumption in 2 years: 1995 and 2000. The rate of technological advance during the periods concerned is quantified in terms of the embodied carbon dioxide emission per yen of product. The results show that the current growth rate of Japanese household consumption is greater than the rate of technological advance to mitigate carbon dioxide emissions. The eco-velocities at the level of individual commodity groups are also examined, and the sources of changes in eco-velocity for each commodity are identified using structural decomposition analysis.

  6. A Review of Technology-Based Youth and Family-Focused Interventions

    PubMed Central

    Prinz, Ronald J.

    2017-01-01

    In the past 10 years, mental and behavioral health has seen a proliferation of technology-based interventions in the form of online and other computer-delivered programs. This paper focuses on technology-based treatment and preventive interventions aimed at benefitting children and adolescents via either involving the parents and families, or only the youth. The review considered only technology-based interventions that had at least one published study with a randomized controlled trial design. Questions being addressed included: (1) What are the technology-based interventions in the mental/behavioral health area that have been systematically evaluated in published studies? (2) What are the common and unique characteristics of these interventions and their application with respect to sample characteristics, target problems, and technology characteristics (platforms, structures, elements, and communication formats)? and (3) Which intervention approaches and strategies have accrued the greatest evidence? The review identified 30 technology-based psychosocial interventions for children and families, 19 of which were parent or family-focused (32 studies) and 11 of which were youth-focused (in 13 studies). For the parent/family-focused interventions, greatest promise was found in those that addressed either youth behavioral problems or depressive/anxious symptoms, as well as more general bolstering of parenting efficacy. The youth-focused interventions showed some promise in reducing depressive/ anxious symptoms. Advantages and disadvantages of the technology-based approaches were considered, and areas for future research and development were discussed. PMID:27787701

  7. A Review of Technology-Based Youth and Family-Focused Interventions.

    PubMed

    MacDonell, Kathleen Watson; Prinz, Ronald J

    2017-06-01

    In the past 10 years, mental and behavioral health has seen a proliferation of technology-based interventions in the form of online and other computer-delivered programs. This paper focuses on technology-based treatment and preventive interventions aimed at benefitting children and adolescents via either involving the parents and families, or only the youth. The review considered only technology-based interventions that had at least one published study with a randomized controlled trial design. Questions being addressed included: (1) What are the technology-based interventions in the mental/behavioral health area that have been systematically evaluated in published studies? (2) What are the common and unique characteristics of these interventions and their application with respect to sample characteristics, target problems, and technology characteristics (platforms, structures, elements, and communication formats)? and (3) Which intervention approaches and strategies have accrued the greatest evidence? The review identified 30 technology-based psychosocial interventions for children and families, 19 of which were parent or family-focused (32 studies) and 11 of which were youth-focused (in 13 studies). For the parent/family-focused interventions, greatest promise was found in those that addressed either youth behavioral problems or depressive/anxious symptoms, as well as more general bolstering of parenting efficacy. The youth-focused interventions showed some promise in reducing depressive/anxious symptoms. Advantages and disadvantages of the technology-based approaches were considered, and areas for future research and development were discussed.

  8. Proceedings of the Hydrokinetic and Wave Energy Technologies Technical and Environmental Issues Workshop

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2006-03-01

    Renewable energy technologies offer the promise of non-polluting alternatives to fossil and nuclear-fueled power plants to meet growing demand for electrical energy. Two emerging categories of renewable energy technologies, hydrokinetic and wave energy conversion devices, offer ways to tap the energy of moving water without impoundment (dams) or diversion required by many conventional hydroelectric facilities. These technologies include devices designed for deployment in natural streams, tidal estuaries, ocean currents, and constructed waterways, as well as devices designed to capture the energy of ocean waves. On October 26-28, 2005, 54 representatives from government, non-governmental organizations, and private business met to (1)more » identify the varieties of hydrokinetic energy and wave technology devices, their stages of development, and the projected cost to bring each to market; (2) identify where these technologies can best operate; (3) identify the potential environmental issues associated with these technologies and possible mitigation measures; (4) develop a list of research needs and/or practical solutions to address unresolved environmental issues. These workshop proceedings include detailed summaries of the 24 presentations made and the discussions that followed.« less

  9. Identifying the Ethical Challenges Encountered by Information Technology Professionals Working within the Nevada Casino Industry

    ERIC Educational Resources Information Center

    Essig, Michael R.

    2014-01-01

    A thematic analysis qualitative study was used to identify the unethical challenges encountered by Information Technology (IT) professionals working within the Nevada casino industry. Fourteen current and former IT leaders working or who worked in the Nevada casino industry were interviewed. Using thematic analysis, nine themes regarding ethical…

  10. Engineering Outreach: A Successful Initiative with Gifted Students in Science and Technology in Hong Kong

    ERIC Educational Resources Information Center

    Chan, Yuen-Yan; Hui, Diane; Dickinson, Anthony R.; Chu, Dennis; Cheng, David Ki-Wai; Cheung, Edward; Ki, Wing-Hung; Lau, Wing-Hong; Wong, Jasper; Lo, Edward W. C.; Luk, Kwai-Man

    2010-01-01

    The primary goal of engineering outreach is to attract prospective students to engineering education and the engineering profession. Gifted students, especially those identified as possessing unusually high abilities in science and technology, are especially promising students to attract to careers in engineering. It is critical to cultivate these…

  11. Selecting Security Technology Providers

    ERIC Educational Resources Information Center

    Schneider, Tod

    2009-01-01

    The world of security technology holds great promise, but it is fraught with opportunities for expensive missteps and misapplications. The quality of the security technology consultants and system integrators one uses will have a direct bearing on how well his school masters this complex subject. Security technology consultants help determine…

  12. Identifying Potential Implications of Technologies on Military and Security Options

    DTIC Science & Technology

    2006-06-01

    Technology Readiness Level (TRL) ratings. THE DISCUSSION Technology surprise occurs through the use of rapidly-emerging and disruptive technologies by...NATO RTB Systems Analysis and Studies Panel, Exploratory Team on the Impact of Disruptive Technologies The objectives of this task group (TG...Workshop on Emerging Disruptive Technologies and the Implications for Defence advanced the view that TTCP should examine the potential of emerging

  13. Science in the Wild: Technology Needs and Opportunities in Scientific Fieldwork

    NASA Technical Reports Server (NTRS)

    Guice, Jon; Hoffower, Heidi; Norvig, Peter (Technical Monitor)

    1999-01-01

    Considering that much contemporary natural science involves field expeditions, fieldwork is an under-studied topic. There is also little information technology specifically designed to support scientific fieldwork, aside from portable scientific instruments. This article describes a variety of fieldwork practices in an interdisciplinary research area, proposes a framework linking types of fieldwork to types of needs in information technology, and identifies promising opportunities for technology development. Technologies that are designed to support the integration of field observations and samples with laboratory work are likely to aid nearly all research teams who conduct fieldwork. However, technologies that support highly detailed representations of field sites will likely trigger the deepest changes in work practice. By way of illustration, we present brief case studies of how fieldwork is done today and how it might be conducted with the introduction of new information technologies.

  14. Promising Practices in Drug Treatment: Findings from Southeast Asia

    ERIC Educational Resources Information Center

    Libretto, Salvatore; Nemes, Susanna; Namur, Jenny; Garrett, Gerald; Hess, Lauren; Kaplan, Linda

    2005-01-01

    In a study to evaluate the drug treatment and aftercare efforts sponsored by the State Department's International Narcotics and Law Enforcement Affairs Bureau, residential Therapeutic Community (TC) treatment programs in three countries in Southeast Asia--Malaysia, Singapore, and Thailand--were examined to identify promising practices and to…

  15. Keeping the Promise

    ERIC Educational Resources Information Center

    Whissemore, Tabitha

    2016-01-01

    Since its launch in September 2015, Heads Up America has collected information on nearly 125 promise programs across the country, many of which were instituted long before President Barack Obama announced the America's College Promise (ACP) plan in 2015. At least 27 new free community college programs have launched in states, communities, and at…

  16. Using the integrative model of behavioral prediction to identify promising message strategies to promote healthy sleep behavior among college students.

    PubMed

    Robbins, Rebecca; Niederdeppe, Jeff

    2015-01-01

    This research used the Integrative Model of Behavioral Prediction (IMBP) to examine cognitive predictors of intentions to engage in healthy sleep behavior among a population of college students. In doing so, we identify promising message strategies to increase healthy sleep behavior during college. In Phase 1, members of a small sample of undergraduates (n = 31) were asked to describe their beliefs about expected outcomes, norms, and perceived behavioral control associated with sleep on an open-ended questionnaire. We analyzed these qualitative responses to create a closed-ended survey about sleep-related attitudes, perceived norms, control beliefs, behavioral intentions, and behavior. In Phase 2, a larger sample of undergraduate students (n = 365) completed the survey. Attitudes and perceived behavioral control were the strongest predictors of both intentions to engage in sleep behavior and self-reported sleep behavior. Control beliefs associated with time management and stress also had substantial room to change, suggesting their potential as message strategies to better promote healthy sleep behavior in college. We conclude with a broader discussion of the study's implications for message design and intervention.

  17. Using Mobile Technology in an Urban High School to Decrease Adult Prompting during in School Transitions for Students Identified with Intellectual Disabilities

    ERIC Educational Resources Information Center

    Christman, Jennifer T.

    2013-01-01

    The aim of this study was to examine the application of video modeling on mobile technology to increase efficiency in the classroom for students identified with intellectual disabilities. Specially, this study sought to identify if video modeling on mobile technology could decrease adult prompting for students with intellectual disabilities during…

  18. Applying deep learning technology to automatically identify metaphase chromosomes using scanning microscopic images: an initial investigation

    NASA Astrophysics Data System (ADS)

    Qiu, Yuchen; Lu, Xianglan; Yan, Shiju; Tan, Maxine; Cheng, Samuel; Li, Shibo; Liu, Hong; Zheng, Bin

    2016-03-01

    Automated high throughput scanning microscopy is a fast developing screening technology used in cytogenetic laboratories for the diagnosis of leukemia or other genetic diseases. However, one of the major challenges of using this new technology is how to efficiently detect the analyzable metaphase chromosomes during the scanning process. The purpose of this investigation is to develop a computer aided detection (CAD) scheme based on deep learning technology, which can identify the metaphase chromosomes with high accuracy. The CAD scheme includes an eight layer neural network. The first six layers compose of an automatic feature extraction module, which has an architecture of three convolution-max-pooling layer pairs. The 1st, 2nd and 3rd pair contains 30, 20, 20 feature maps, respectively. The seventh and eighth layers compose of a multiple layer perception (MLP) based classifier, which is used to identify the analyzable metaphase chromosomes. The performance of new CAD scheme was assessed by receiver operation characteristic (ROC) method. A number of 150 regions of interest (ROIs) were selected to test the performance of our new CAD scheme. Each ROI contains either interphase cell or metaphase chromosomes. The results indicate that new scheme is able to achieve an area under the ROC curve (AUC) of 0.886+/-0.043. This investigation demonstrates that applying a deep learning technique may enable to significantly improve the accuracy of the metaphase chromosome detection using a scanning microscopic imaging technology in the future.

  19. Promising Practices in Drug Treatment: Findings from Latin America

    ERIC Educational Resources Information Center

    Nemes, Susanna; Libretto, Salvatore; Garrett, Gerald; Johansson, Anna Carin; Hess, Lauren

    2005-01-01

    In a study to evaluate the drug treatment and aftercare efforts sponsored by the State Department's International Narcotics and Law Enforcement Affairs Bureau, residential Therapeutic Community (TC) treatment programs in three Latin American countries--Brazil, Peru and Argentina--were examined to identify promising practices and to assess lessons…

  20. Membrane technology as a promising alternative in biodiesel production: a review.

    PubMed

    Shuit, Siew Hoong; Ong, Yit Thai; Lee, Keat Teong; Subhash, Bhatia; Tan, Soon Huat

    2012-01-01

    In recent years, environmental problems caused by the use of fossil fuels and the depletion of petroleum reserves have driven the world to adopt biodiesel as an alternative energy source to replace conventional petroleum-derived fuels because of biodiesel's clean and renewable nature. Biodiesel is conventionally produced in homogeneous, heterogeneous, and enzymatic catalysed processes, as well as by supercritical technology. All of these processes have their own limitations, such as wastewater generation and high energy consumption. In this context, the membrane reactor appears to be the perfect candidate to produce biodiesel because of its ability to overcome the limitations encountered by conventional production methods. Thus, the aim of this paper is to review the production of biodiesel with a membrane reactor by examining the fundamental concepts of the membrane reactor, its operating principles and the combination of membrane and catalyst in the catalytic membrane. In addition, the potential of functionalised carbon nanotubes to serve as catalysts while being incorporated into the membrane for transesterification is discussed. Furthermore, this paper will also discuss the effects of process parameters for transesterification in a membrane reactor and the advantages offered by membrane reactors for biodiesel production. This discussion is followed by some limitations faced in membrane technology. Nevertheless, based on the findings presented in this review, it is clear that the membrane reactor has the potential to be a breakthrough technology for the biodiesel industry. Copyright © 2012 Elsevier Inc. All rights reserved.

  1. Federal Technology Catalog 1982: Summaries of practical technology

    NASA Astrophysics Data System (ADS)

    The catalog presents summaries of practical technology selected for commercial potential and/or promising applications to the fields of computer technology, electrotechnology, energy, engineering, life sciences, machinery and tools, manufacturing, materials, physical sciences, and testing and instrumentation. Each summary not only describes a technology, but gives a source for further information. This publication describes some 1,100 new processes, inventions, equipment, software, and techniques developed by and for dozens of Federal agencies during 1982. Included is coverage of NASA Tech Briefs, DOE Energygrams, and Army Manufacturing Notes.

  2. Between worst and best: developing criteria to identify promising practices in health promotion and disease prevention for the Canadian Best Practices Portal.

    PubMed

    Fazal, Nadia; Jackson, Suzanne F; Wong, Katy; Yessis, Jennifer; Jetha, Nina

    2017-11-01

    In health promotion and chronic disease prevention, both best and promising practices can provide critical insights into what works for enhancing the healthrelated outcomes of individuals and communities, and how/why these practices work in different situations and contexts. The promising practices criteria were developed using the Public Health Agency of Canada's (PHAC's) existing best practices criteria as the foundation. They were modified and pilot tested (three rounds) using published interventions. Theoretical and methodological issues and challenges were resolved via consultation and in-depth discussions with a working group. The team established a set of promising practices criteria, which differentiated from the best practices criteria via six specific measures. While a number of complex challenges emerged in the development of these criteria, they were thoroughly discussed, debated and resolved. The Canadian Best Practices Portal's screening criteria allow one to screen for both best and promising practices in the fields of public health, health promotion, chronic disease prevention, and potentially beyond.

  3. JSC research and technology

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The primary roles and missions of JSC incorporate all aspects of human presence in space. Therefore, the Center is involved in the development of technology that will allow humans to stay longer in Earth orbit, allow safe flight in space, and provide capabilities to explore the Moon and Mars. The Center's technology emphasis areas include human spacecraft development, human support systems and infrastructure, and human spacecraft operations. Safety and reliability are critical requirements for the technologies that JSC pursues for long-duration use in space. One of the objectives of technology development at the Center is to give employees the opportunity to enhance their technological expertise and project management skills by defining, designing, and developing projects that are vital to the Center's strategy for the future. This report is intended to communicate within and outside the Agency our research and technology (R&T) accomplishments, as well as inform Headquarters program managers and their constituents of the significant accomplishments that have promise for future Agency programs. While not inclusive of all R&T efforts, the report presents a comprehensive summary of JSC projects in which substantial progress was made in the 1992 fiscal year. At the beginning of each project description, names of the Principal Investigator (PI) and the Technical Monitor (TM) are given, followed by their JSC mail codes or their company or university affiliations. The funding sources and technology focal points are identified in the index.

  4. Promising treatments in development for food allergies.

    PubMed

    Rancé, Fabienne

    2004-11-01

    Up to 6% of young children and 2% of adults suffer from food allergy. Among them many have IgE-mediated food allergy, a condition with potentially fatal allergic reactions. The only proven treatment is avoidance of the offending food, which can be identified using standardised allergic tests. However, several studies have addressed possible definite treatment options for food allergy. Immunotherapy, administered orally or by systemic injections, shows promising preliminary results, but these therapeutics are based on studies with insufficient scientific support, or are associated with a high risk of severe side effects. At present, no studies can support pharmacotherapy. However, promising results were recently published with anti-IgE antibodies in a human trial, and various approaches in a mouse model of food allergy (chinese herbal medicine, specific modulation of the T-cell response). Rapidly evolving findings might provide hope for a cure for food allergy in the near future.

  5. Service-Learning: Promise and Possibility in Post-Secondary Education

    ERIC Educational Resources Information Center

    Kalles, Susan; Ryan, Thomas G.

    2015-01-01

    Herein we identify and address promising practices, essential theories, and related cautions within service-learning. The argument that service-learning is an organized community service which is connected to curriculum in an effort to deepen learning around content was scrutinized and endorsed. We envisioned service-learning as more than a joint…

  6. Artificial Intelligence in Surgery: Promises and Perils.

    PubMed

    Hashimoto, Daniel A; Rosman, Guy; Rus, Daniela; Meireles, Ozanan R

    2018-07-01

    The aim of this review was to summarize major topics in artificial intelligence (AI), including their applications and limitations in surgery. This paper reviews the key capabilities of AI to help surgeons understand and critically evaluate new AI applications and to contribute to new developments. AI is composed of various subfields that each provide potential solutions to clinical problems. Each of the core subfields of AI reviewed in this piece has also been used in other industries such as the autonomous car, social networks, and deep learning computers. A review of AI papers across computer science, statistics, and medical sources was conducted to identify key concepts and techniques within AI that are driving innovation across industries, including surgery. Limitations and challenges of working with AI were also reviewed. Four main subfields of AI were defined: (1) machine learning, (2) artificial neural networks, (3) natural language processing, and (4) computer vision. Their current and future applications to surgical practice were introduced, including big data analytics and clinical decision support systems. The implications of AI for surgeons and the role of surgeons in advancing the technology to optimize clinical effectiveness were discussed. Surgeons are well positioned to help integrate AI into modern practice. Surgeons should partner with data scientists to capture data across phases of care and to provide clinical context, for AI has the potential to revolutionize the way surgery is taught and practiced with the promise of a future optimized for the highest quality patient care.

  7. Technology-Enhanced Formative Assessment: A Research-Based Pedagogy for Teaching Science with Classroom Response Technology

    ERIC Educational Resources Information Center

    Beatty, Ian D.; Gerace, William J.

    2009-01-01

    "Classroom response systems" (CRSs) are a promising instructional technology, but most literature on CRS use fails to distinguish between technology and pedagogy, to define and justify a pedagogical perspective, or to discriminate between pedagogies. "Technology-enhanced formative assessment" (TEFA) is our pedagogy for CRS-based science…

  8. Identifying Effective Policy and Technologic Reforms for Sustainable Groundwater Management in Oman

    NASA Astrophysics Data System (ADS)

    Madani, K.; Zekri, S.; Karimi, A.

    2014-12-01

    Oman has gone through three decades of efforts aimed at addressing groundwater over-pumping and the consequent seawater intrusion. Example of measures adopted by the government since the 1990's include a vast subsidy program of irrigation modernization, a freeze on drilling new wells, delimitation of several no-drill zones, a crop substitution program, re-use of treated wastewater and construction of recharge dams. With no major success through these measures, the government laid the ground for water quotas by creating a new regulation in 1995. Nevertheless, groundwater quotas have not been enforced to date due to the high implementation and monitoring costs of traditional flow meters. This presentation discusses how sustainable groundwater management can be secured in Oman using a suit of policy and technologic reforms at a reasonable economic, political and practical cost. Data collected from farms with smart meters and low-cost wireless smart irrigation systems have been used to propose sustainable groundwater withdrawal strategies for Oman using a detailed hydro-economic model that couples a MODFLOW-SEAWAT model of the coastal aquifers with a dynamic profit maximization model. The hydro-economic optimization model was flexible to be run both as a social planner model to maximize the social welfare in the region, and as an agent-based model to capture the behavior of farmers interested in maximizing their profits independently. This flexibility helped capturing the trade-off between the optimality of the social planner solution developed at the system's level and its practicality (stability) with respect to the concerns and behaviors of the profit-maximizing farmers. The idetified promising policy and technolgical reforms for Oman include strict enforcement of groundwater quotas, smart metering, changing crop mixes, improving irrigation technologies, and revising geographical distribution of the farming activities. The presentation will discuss how different

  9. Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research

    PubMed Central

    King, Kevin; Grazette, Luanda P.; Paltoo, Dina N.; McDevitt, John T.; Sia, Samuel K.; Barrett, Paddy M.; Apple, Fred S.; Gurbel, Paul A.; Weissleder, Ralph; Leeds, Hilary; Iturriaga, Erin J.; Rao, Anupama; Adhikari, Bishow; Desvigne-Nickens, Patrice; Galis, Zorina S.; Libby, Peter

    2016-01-01

    Point-of-care technologies (POC or POCT) are enabling innovative cardiovascular diagnostics that promise to improve patient care across diverse clinical settings. The National Heart, Lung, and Blood Institute convened a working group to discuss POCT in cardiovascular medicine. The multidisciplinary working group, which included clinicians, scientists, engineers, device manufacturers, regulatory officials, and program staff, reviewed the state of the POCT field; discussed opportunities for POCT to improve cardiovascular care, realize the promise of precision medicine, and advance the clinical research enterprise; and identified barriers facing translation and integration of POCT with existing clinical systems. A POCT development roadmap emerged to guide multidisciplinary teams of biomarker scientists, technologists, health care providers, and clinical trialists as they: 1) formulate needs assessments; 2) define device design specifications; 3) develop component technologies and integrated systems; 4) perform iterative pilot testing; and 5) conduct rigorous prospective clinical testing to ensure that POCT solutions have substantial effects on cardiovascular care. PMID:26977455

  10. Text categorization models for identifying unproven cancer treatments on the web.

    PubMed

    Aphinyanaphongs, Yin; Aliferis, Constantin

    2007-01-01

    The nature of the internet as a non-peer-reviewed (and largely unregulated) publication medium has allowed wide-spread promotion of inaccurate and unproven medical claims in unprecedented scale. Patients with conditions that are not currently fully treatable are particularly susceptible to unproven and dangerous promises about miracle treatments. In extreme cases, fatal adverse outcomes have been documented. Most commonly, the cost is financial, psychological, and delayed application of imperfect but proven scientific modalities. To help protect patients, who may be desperately ill and thus prone to exploitation, we explored the use of machine learning techniques to identify web pages that make unproven claims. This feasibility study shows that the resulting models can identify web pages that make unproven claims in a fully automatic manner, and substantially better than previous web tools and state-of-the-art search engine technology.

  11. Technologies for Continuous Glucose Monitoring: Current Problems and Future Promises

    PubMed Central

    Vaddiraju, Santhisagar; Burgess, Diane J; Tomazos, Ioannis; Jain, Faquir C; Papadimitrakopoulos, Fotios

    2010-01-01

    Devices for continuous glucose monitoring (CGM) are currently a major focus of research in the area of diabetes management. It is envisioned that such devices will have the ability to alert a diabetes patient (or the parent or medical care giver of a diabetes patient) of impending hypoglycemic/hyperglycemic events and thereby enable the patient to avoid extreme hypoglycemic/hyperglycemic excursions as well as minimize deviations outside the normal glucose range, thus preventing both life-threatening events and the debilitating complications associated with diabetes. It is anticipated that CGM devices will utilize constant feedback of analytical information from a glucose sensor to activate an insulin delivery pump, thereby ultimately realizing the concept of an artificial pancreas. Depending on whether the CGM device penetrates/breaks the skin and/or the sample is measured extracorporeally, these devices can be categorized as totally invasive, minimally invasive, and noninvasive. In addition, CGM devices are further classified according to the transduction mechanisms used for glucose sensing (i.e., electrochemical, optical, and piezoelectric). However, at present, most of these technologies are plagued by a variety of issues that affect their accuracy and long-term performance. This article presents a critical comparison of existing CGM technologies, highlighting critical issues of device accuracy, foreign body response, calibration, and miniaturization. An outlook on future developments with an emphasis on long-term reliability and performance is also presented. PMID:21129353

  12. Scientific Futures. Selected Areas of Opportunity for the Office of Science and Technology Policy, the National Science Foundation, and Selected Federal Departments and Agencies.

    ERIC Educational Resources Information Center

    National Academy of Sciences, Washington, DC.

    In response to the President's Office of Science and Technology Policy request to identify promising areas for U.S. research investment in science and technology, this report contains briefings by outstanding researchers in several fields of science. This volume is the fifth in a series of briefings which are used to anticipate important new…

  13. Giving up Technology and Social Media: Why University Lecturers Stop Using Technology in Teaching

    ERIC Educational Resources Information Center

    Shelton, Chris

    2017-01-01

    University lecturers use a wide range of technologies when teaching and there has been much research into how particular technologies are adopted. However, there are also many technologies that, despite early promise, are no longer being used in university teaching and have been abandoned by institutions or individuals. This article presents the…

  14. Technology and the boundaries of the hospital: three emerging technologies.

    PubMed

    Goldsmith, Jeff

    2004-01-01

    U.S. hospitals have proved remarkably adept at altering their service offerings to incorporate new technologies. New technologies threatened to undercut hospitals' central role in health care delivery in the 1980s. An array of new technologies promise yet again to alter the boundaries of hospitals' franchise. These technologies will not only continue the shift away from acute, inpatient care that we have seen for the past thirty years but will also challenge hospitals to collaborate more effectively with physicians and technology developers. How hospitals and policymakers respond to these emerging technologies will help determine whether hospitals remain at the center of the U.S. health system.

  15. A feasibility study for advanced technology integration for general aviation

    NASA Technical Reports Server (NTRS)

    Kohlman, D. L.; Matsuyama, G. T.; Hawley, K. E.; Meredith, P. T.

    1980-01-01

    An investigation was conducted to identify candidate technologies and specific developments which offer greatest promise for improving safety, fuel efficiency, performance, and utility of general aviation airplanes. Interviews were conducted with general aviation airframe and systems manufacturers and NASA research centers. The following technologies were evaluated for use in airplane design tradeoff studies conducted during the study: avionics, aerodynamics, configurations, structures, flight controls, and propulsion. Based on industry interviews and design tradeoff studies, several recommendations were made for further high payoff research. The most attractive technologies for use by the general aviation industry appear to be advanced engines, composite materials, natural laminar flow airfoils, and advanced integrated avionics systems. The integration of these technologies in airplane design can yield significant increases in speeds, ranges, and payloads over present aircraft with 40 percent to 50 percent reductions in fuel used.

  16. Identifying Interdisciplinary Research Collaboration in Instructional Technology

    ERIC Educational Resources Information Center

    Cho, Yonjoo

    2017-01-01

    Interdisciplinarity is defined as communication and collaboration across academic disciplines. The instructional technology (IT) field has claimed to have an interdisciplinary nature influenced by neighboring fields such as psychology, communication, and management. However, it has been difficult to find outstanding evidence of the field's…

  17. Promising More Information

    NASA Technical Reports Server (NTRS)

    2003-01-01

    When NASA needed a real-time, online database system capable of tracking documentation changes in its propulsion test facilities, engineers at Stennis Space Center joined with ECT International, of Brookfield, Wisconsin, to create a solution. Through NASA's Dual-Use Program, ECT developed Exdata, a software program that works within the company's existing Promise software. Exdata not only satisfied NASA s requirements, but also expanded ECT s commercial product line. Promise, ECT s primary product, is an intelligent software program with specialized functions for designing and documenting electrical control systems. An addon to AutoCAD software, Promis e generates control system schematics, panel layouts, bills of material, wire lists, and terminal plans. The drawing functions include symbol libraries, macros, and automatic line breaking. Primary Promise customers include manufacturing companies, utilities, and other organizations with complex processes to control.

  18. Watch IT: The Risks and Promises of Information Technologies for Education.

    ERIC Educational Resources Information Center

    Burbules, Nicholas C.; Callister, Thomas A., Jr.

    This book is an examination of several critical issues and controversies concerning the potential of new information technology (IT) for education. In a series of interrelated essays, the book explores such issues as access, credibility, new approaches to reading and writing, the glut of information, privacy, censorship, commercialization, and…

  19. Achieving Educational Excellence by Increasing Access to Knowledge: Discussion Document. Report of the Task Force on Education Network Technology.

    ERIC Educational Resources Information Center

    National Education Goals Panel, Washington, DC.

    Internetworked communications restructures relationships among educators, learners, and knowledge and information, and promises a systemic acceleration of the pace of educational change. In this report, the Task Force on Education Network Technology identifies the following rationales for deployment and utilization of such communications: to…

  20. Virtual Reality and Its Potential Use in Special Education. Identifying Emerging Issues and Trends in Technology for Special Education.

    ERIC Educational Resources Information Center

    Woodward, John

    As part of a 3-year study to identify emerging issues and trends in technology for special education, this paper addresses the possible contributions of virtual reality technology to educational services for students with disabilities. An example of the use of virtual reality in medical imaging introduces the paper and leads to a brief review of…

  1. Improving High School Success: Searching for Evidence of Promise

    ERIC Educational Resources Information Center

    Mazzeo, Christopher; Fleischman, Steve; Heppen, Jessica; Jahangir, Theresa

    2016-01-01

    Improving the nation's high schools--particularly those that are low-performing--involves challenges that are far easier to catalog than to surmount. In this chapter, the authors identify a handful of promising approaches that can help to achieve the goal that all students will graduate from high school well-prepared for further learning,…

  2. Climate change and eHealth: a promising strategy for health sector mitigation and adaptation

    PubMed Central

    Holmner, Åsa; Rocklöv, Joacim; Ng, Nawi; Nilsson, Maria

    2012-01-01

    Climate change is one of today's most pressing global issues. Policies to guide mitigation and adaptation are needed to avoid the devastating impacts of climate change. The health sector is a significant contributor to greenhouse gas emissions in developed countries, and its climate impact in low-income countries is growing steadily. This paper reviews and discusses the literature regarding health sector mitigation potential, known and hypothetical co-benefits, and the potential of health information technology, such as eHealth, in climate change mitigation and adaptation. The promising role of eHealth as an adaptation strategy to reduce societal vulnerability to climate change, and the link's between mitigation and adaptation, are also discussed. The topic of environmental eHealth has gained little attention to date, despite its potential to contribute to more sustainable and green health care. A growing number of local and global initiatives on ‘green information and communication technology (ICT)’ are now mentioning eHealth as a promising technology with the potential to reduce emission rates from ICT use. However, the embracing of eHealth is slow because of limitations in technological infrastructure, capacity and political will. Further research on potential emissions reductions and co-benefits with green ICT, in terms of health outcomes and economic effectiveness, would be valuable to guide development and implementation of eHealth in health sector mitigation and adaptation policies. PMID:22679398

  3. Climate change and eHealth: a promising strategy for health sector mitigation and adaptation.

    PubMed

    Holmner, Asa; Rocklöv, Joacim; Ng, Nawi; Nilsson, Maria

    2012-01-01

    Climate change is one of today's most pressing global issues. Policies to guide mitigation and adaptation are needed to avoid the devastating impacts of climate change. The health sector is a significant contributor to greenhouse gas emissions in developed countries, and its climate impact in low-income countries is growing steadily. This paper reviews and discusses the literature regarding health sector mitigation potential, known and hypothetical co-benefits, and the potential of health information technology, such as eHealth, in climate change mitigation and adaptation. The promising role of eHealth as an adaptation strategy to reduce societal vulnerability to climate change, and the link's between mitigation and adaptation, are also discussed. The topic of environmental eHealth has gained little attention to date, despite its potential to contribute to more sustainable and green health care. A growing number of local and global initiatives on 'green information and communication technology (ICT)' are now mentioning eHealth as a promising technology with the potential to reduce emission rates from ICT use. However, the embracing of eHealth is slow because of limitations in technological infrastructure, capacity and political will. Further research on potential emissions reductions and co-benefits with green ICT, in terms of health outcomes and economic effectiveness, would be valuable to guide development and implementation of eHealth in health sector mitigation and adaptation policies.

  4. Predictive Validity of an Empirical Approach for Selecting Promising Message Topics: A Randomized-Controlled Study

    PubMed Central

    Lee, Stella Juhyun; Brennan, Emily; Gibson, Laura Anne; Tan, Andy S. L.; Kybert-Momjian, Ani; Liu, Jiaying; Hornik, Robert

    2016-01-01

    Several message topic selection approaches propose that messages based on beliefs pretested and found to be more strongly associated with intentions will be more effective in changing population intentions and behaviors when used in a campaign. This study aimed to validate the underlying causal assumption of these approaches which rely on cross-sectional belief–intention associations. We experimentally tested whether messages addressing promising themes as identified by the above criterion were more persuasive than messages addressing less promising themes. Contrary to expectations, all messages increased intentions. Interestingly, mediation analyses showed that while messages deemed promising affected intentions through changes in targeted promising beliefs, messages deemed less promising also achieved persuasion by influencing nontargeted promising beliefs. Implications for message topic selection are discussed. PMID:27867218

  5. Using statistical text classification to identify health information technology incidents

    PubMed Central

    Chai, Kevin E K; Anthony, Stephen; Coiera, Enrico; Magrabi, Farah

    2013-01-01

    Objective To examine the feasibility of using statistical text classification to automatically identify health information technology (HIT) incidents in the USA Food and Drug Administration (FDA) Manufacturer and User Facility Device Experience (MAUDE) database. Design We used a subset of 570 272 incidents including 1534 HIT incidents reported to MAUDE between 1 January 2008 and 1 July 2010. Text classifiers using regularized logistic regression were evaluated with both ‘balanced’ (50% HIT) and ‘stratified’ (0.297% HIT) datasets for training, validation, and testing. Dataset preparation, feature extraction, feature selection, cross-validation, classification, performance evaluation, and error analysis were performed iteratively to further improve the classifiers. Feature-selection techniques such as removing short words and stop words, stemming, lemmatization, and principal component analysis were examined. Measurements κ statistic, F1 score, precision and recall. Results Classification performance was similar on both the stratified (0.954 F1 score) and balanced (0.995 F1 score) datasets. Stemming was the most effective technique, reducing the feature set size to 79% while maintaining comparable performance. Training with balanced datasets improved recall (0.989) but reduced precision (0.165). Conclusions Statistical text classification appears to be a feasible method for identifying HIT reports within large databases of incidents. Automated identification should enable more HIT problems to be detected, analyzed, and addressed in a timely manner. Semi-supervised learning may be necessary when applying machine learning to big data analysis of patient safety incidents and requires further investigation. PMID:23666777

  6. The Promise of NLP and Speech Processing Technologies in Language Assessment

    ERIC Educational Resources Information Center

    Chapelle, Carol A.; Chung, Yoo-Ree

    2010-01-01

    Advances in natural language processing (NLP) and automatic speech recognition and processing technologies offer new opportunities for language testing. Despite their potential uses on a range of language test item types, relatively little work has been done in this area, and it is therefore not well understood by test developers, researchers or…

  7. Identifying promising accessions of cherry tomato: a sensory strategy using consumers and chefs.

    PubMed

    Rocha, Mariella C; Deliza, Rosires; Ares, Gastón; Freitas, Daniela De G C; Silva, Aline L S; Carmo, Margarida G F; Abboud, Antonio C S

    2013-06-01

    An increased production of cherry and gourmet tomato cultivars that are harvested at advanced colour stages and sold at a higher price has been observed in the last 10 years. In this context, producers need information on the sensory characteristics of new cultivars and their perception by potential consumers. The aim of the present work was to obtain a sensory characterisation of nine cherry tomato cultivars produced under Brazilian organic cultivation conditions from a chef and consumer perspective. Nine organic cherry tomato genotypes were evaluated by ten chefs using an open-ended question and by 110 consumers using a check-all-that-apply question. Both methodologies provided similar information on the sensory characteristics of the cherry tomato accessions. The superimposed representation of the samples in a multiple factor analysis was similar for consumers' and chefs' descriptions (RV coefficient 0.728), although they used different methodologies. According to both panels, cherry tomatoes were sorted into five groups of samples with similar sensory characteristics. Results from the present work may provide information to help organic producers in the selection of the most promising cultivars for cultivation, taking into account consumers' and chefs' perceptions, as well as in the design of communication and marketing strategies. © 2012 Society of Chemical Industry.

  8. Literature review on monitoring technologies and their outcomes in independently living elderly people.

    PubMed

    Peetoom, Kirsten K B; Lexis, Monique A S; Joore, Manuela; Dirksen, Carmen D; De Witte, Luc P

    2015-07-01

    To obtain insight into what kind of monitoring technologies exist to monitor activity in-home, what the characteristics and aims of applying these technologies are, what kind of research has been conducted on their effects and what kind of outcomes are reported. A systematic document search was conducted within the scientific databases Pubmed, Embase, Cochrane, PsycINFO and Cinahl, complemented by Google Scholar. Documents were included in this review if they reported on monitoring technologies that detect activities of daily living (ADL) or significant events, e.g. falls, of elderly people in-home, with the aim of prolonging independent living. Five main types of monitoring technologies were identified: PIR motion sensors, body-worn sensors, pressure sensors, video monitoring and sound recognition. In addition, multicomponent technologies and smart home technologies were identified. Research into the use of monitoring technologies is widespread, but in its infancy, consisting mainly of small-scale studies and including few longitudinal studies. Monitoring technology is a promising field, with applications to the long-term care of elderly persons. However, monitoring technologies have to be brought to the next level, with longitudinal studies that evaluate their (cost-) effectiveness to demonstrate the potential to prolong independent living of elderly persons. [Box: see text].

  9. Harness the Power of Technology

    ERIC Educational Resources Information Center

    Duncan, Arne

    2011-01-01

    Today, U.S. educators are teaching in the midst of a technological revolution. Technology promises to provide innovative solutions in the nation's classrooms, just as it has transformed the way people communicate, socialize, and conduct business. In this article, the author argues that now is the time to harness technology to revolutionize the way…

  10. The Promise of Virtual Teams: Identifying Key Factors in Effectiveness and Failure

    ERIC Educational Resources Information Center

    Horwitz, Frank M.; Bravington, Desmond; Silvis, Ulrik

    2006-01-01

    Purpose: The aim of the investigation is to identify enabling and disenabling factors in the development and operation of virtual teams; to evaluate the importance of factors such as team development, cross-cultural variables, leadership, communication and social cohesion as contributors to virtual team effectiveness. Design/methodology/approach:…

  11. LEVERAGING TECHNOLOGY TO ENHANCE ADDICTION TREATMENT AND RECOVERY

    PubMed Central

    Marsch, Lisa A.

    2012-01-01

    Technology such as the Internet and mobile phones offers considerable promise for affecting the assessment, prevention, and treatment of and recovery from substance use disorders. Technology may enable entirely new models of behavioral health care within and outside of formal systems of care. This article reviews the promise of technology-based therapeutic tools for affecting the quality and reach of addiction treatment and recovery support systems, as well as the empirical support to date for this approach. Potential models for implementing technology-based interventions targeting substance use disorders are described. Opportunities to optimize the effectiveness and impact of technology-based interventions targeting addiction and recovery, along with outstanding research needs, are discussed. PMID:22873192

  12. Leveraging technology to enhance addiction treatment and recovery.

    PubMed

    Marsch, Lisa A

    2012-01-01

    Technology such as the Internet and mobile phones offers considerable promise for affecting the assessment, prevention, and treatment of and recovery from substance use disorders. Technology may enable entirely new models of behavioral health care within and outside of formal systems of care. This article reviews the promise of technology-based therapeutic tools for affecting the quality and reach of addiction treatment and recovery support systems, as well as the empirical support to date for this approach. Potential models for implementing technology-based interventions targeting substance use disorders are described. Opportunities to optimize the effectiveness and impact of technology-based interventions targeting addiction and recovery, along with outstanding research needs, are discussed.

  13. The Science and Technology of the US National Missile Defense System

    NASA Astrophysics Data System (ADS)

    Postol, Theodore A.

    2010-03-01

    The National Missile Defense System utilizes UHF and X-band radars for search, track and discrimination, and interceptors that use long-wave infrared sensors to identify and home on attacking warheads. The radars and infrared sensors in the missile defense system perform at near the theoretical limits predicted by physics. However, in spite of the fantastic technical advances in sensor technology, signal processing, and computational support functions, the National Missile Defense System cannot be expected to ever work in realistic combat environments. This talk will describe why these impressive technologies can never deliver on the promise of a credible defense against long-range ballistic missiles.

  14. Challenges to the introduction of new technologies to dental practice.

    PubMed

    Barnett, Michael L

    2006-01-01

    Despite promising breakthroughs in basic biomedical science, the pace at which innovative and disruptive new technologies are developed and introduced into dental practice lags behind that of medicine. This is largely a result of resource issues, both financial and human, as well as determinants in the marketplace. For example, the cost of developing a new drug or technology for dentistry and bringing it to market is often disproportionably high relative to the size of the dental market, thereby making it commercially unfeasible to pursue development. When a new technology is commercialized, its successful introduction can be facilitated by research that makes a compelling case for effective use. As our understanding of mechanisms of disease pathogenesis progresses, identifying compounds and technologies with applicability to both oral and systemic diseases could change the economics of dental product development and lead to additional innovative advances in our field.

  15. Model of areas for identifying risks influencing the compliance of technological processes and products

    NASA Astrophysics Data System (ADS)

    Misztal, A.; Belu, N.

    2016-08-01

    Operation of every company is associated with the risk of interfering with proper performance of its fundamental processes. This risk is associated with various internal areas of the company, as well as the environment in which it operates. From the point of view of ensuring compliance of the course of specific technological processes and, consequently, product conformity with requirements, it is important to identify these threats and eliminate or reduce the risk of their occurrence. The purpose of this article is to present a model of areas of identifying risk affecting the compliance of processes and products, which is based on multiregional targeted monitoring of typical places of interference and risk management methods. The model is based on the verification of risk analyses carried out in small and medium-sized manufacturing companies in various industries..

  16. The Kalamazoo Promise Scholarship

    ERIC Educational Resources Information Center

    Bartik, Timothy J.; Lachowska, Marta

    2014-01-01

    This study takes advantage of the unexpected announcement of the Kalamazoo Promise to study its effects on student achievement and behavior in high school. The Kalamazoo Promise provides college scholarships to graduates of Kalamazoo Public Schools (KPS), a midsized urban school district in Michigan that is racially and economically diverse.…

  17. The Promise of Education Information Systems: How Technology Can Improve School Management and Success

    ERIC Educational Resources Information Center

    Levenson, Nathan; Boser, Ulrich

    2014-01-01

    Many school district strategic plans and education conferences are aggressively embracing technology to improve teaching and learning. Classroom technology typically includes blended learning, personalized learning, online courses for students, and professional development for teachers, among many other things. As districts wrestle with tighter…

  18. Identifying and Synchronizing Health Information Technology (HIT) Events from FDA Medical Device Reports.

    PubMed

    Kang, Hong; Wang, Frank; Zhou, Sicheng; Miao, Qi; Gong, Yang

    2017-01-01

    Health information technology (HIT) events, a subtype of patient safety events, pose a major threat and barrier toward a safer healthcare system. It is crucial to gain a better understanding of the nature of the errors and adverse events caused by current HIT systems. The scarcity of HIT event-exclusive databases and event reporting systems indicates the challenge of identifying the HIT events from existing resources. FDA Manufacturer and User Facility Device Experience (MAUDE) database is a potential resource for HIT events. However, the low proportion and the rapid evolvement of HIT-related events present challenges for distinguishing them from other equipment failures and hazards. We proposed a strategy to identify and synchronize HIT events from MAUDE by using a filter based on structured features and classifiers based on unstructured features. The strategy will help us develop and grow an HIT event-exclusive database, keeping pace with updates to MAUDE toward shared learning.

  19. Mission in the works promises precise global topographic data

    USGS Publications Warehouse

    Farr, T.; Evans, D.; Zebker, H.; Harding, D.; Bufton, J.; Dixon, T.; Vetrella, S.; Gesch, D.B.

    1995-01-01

    Significant deficiencies in the quality of today's topographic data severely limit scientific applications. Very few available data sets meet the stringent requirements of 10–30 m for global digital topography and 5 m or better vertical accuracy, and existing satellite systems are unlikely to fulfill these requirements. The Joint Topographic Science Working Group, appointed by NASA and the Italian Space Agency, concluded that radar interferometry coupled with a laser altimeter would be the most promising approach for improving data quality. By providing its own illumination at a wavelength Ion g enough to (e.g., λ = 25 cm) to penetrate clouds and rain, the interferometer would provide a global, uniform high-quality topographic data set. One mission under study, TOPSAT, is well positioned to fill this niche and promises to pave the way toward a more standardized and precise topographic database. TOPSAT would be an international mission, designed to make use of recent technology advances in such programs as NASA's New Millennium. It could be ready to launch by the end of this decade.

  20. Stem cell therapy: the great promise in lung disease.

    PubMed

    Siniscalco, Dario; Sullo, Nikol; Maione, Sabatino; Rossi, Francesco; D'Agostino, Bruno

    2008-06-01

    Lung injuries are leading causes of morbidity and mortality worldwide. Pulmonary diseases such as asthma or chronic obstructive pulmonary disease characterized by loss of lung elasticity, small airway tethers, and luminal obstruction with inflammatory mucoid secretions, or idiopathic pulmonary fibrosis characterized by excessive matrix deposition and destruction of the normal lung architecture, have essentially symptomatic treatments and their management is costly to the health care system.Regeneration of tissue by stem cells from endogenous, exogenous, and even genetically modified cells is a promising novel therapy. The use of adult stem cells to help with lung regeneration and repair could be a newer technology in clinical and regenerative medicine. In fact, different studies have shown that bone marrow progenitor cells contribute to repair and remodeling of lung in animal models of progressive pulmonary hypertension.Therefore, lung stem cell biology may provide novel approaches to therapy and could represent a great promise for the future of molecular medicine. In fact, several diseases can be slowed or even blocked by stem cell transplantation.

  1. Transit Technology Evaluation - A Literature Capsule

    DOT National Transportation Integrated Search

    1981-11-01

    The report is designed to make the literature on transportation concerning promising new transit technology more accessible to users. The Transit Technology Evaluation Program investigates the technical, social, and economic factors involved in the p...

  2. The Promise of E-Platform Technology in Medical Education.

    PubMed

    Dawd, Siraj

    2016-03-01

    Increasing the number as well as improving the capacity and quality of medical professionals to achieve an equitable health care for all is a global priority and a global challenge. In developing countries, which are facing the largest burden of disease, to achieve the above stated objective, there is a big need for more well-trained, competent and dedicated health care providers. Currently, there is a well-documented shortage of trained health workers globally, with the poorest countries having the greatest shortfalls. The time tested, traditional approach of training health care force by importing professionals from overseas is not only prohibitively expensive but also not sufficient to achieve the scale and pace of the required human capacity building. Considering this fact, distance learning programs, which include m-Health as well as other information technology (IT) platforms and tools, can provide unique, timely, cost-effective, easily scalable and valuable opportunities to expand access to training health care manpower in developing countries where the shortage is critical.

  3. TurboBrayton Cryocooler: A Flight Worthy and Promising Future

    NASA Technical Reports Server (NTRS)

    Gibbon, Judith A.; Swift, Walt L.; Zagarola, Mark V.; DiPirro, Mike; Whitehouse, Paul

    1999-01-01

    A new development in cryocooler technology, a reverse TurboBrayton cycle cryocooler, developed by Creare, Inc. of Hanover, NH, has now been flight tested. This cooler provides high reliability and long life. With no linear moving components common in current flight cryocoolers, the TurboBrayton cooler requires no active control systems to provide a vibration-free signature. The cooler provides first stage cooling for advanced cryogenic systems and serves as a direct replacement for stored cryogen systems with a longer lifetime. Following a successful flight on STS-95, a TurboBrayton cryocooler will be flown on Hubble Space Telescope (HST) in 2000 to provide renewed refrigeration capability for the Near Infrared Camera and Multi-Object Spectrometer (NICMOS). The TurboBrayton cycle cooler is a promising technology already being considered for additional flight programs such as Next Generation Space Telescope (NGST) and Constellation X. These future missions require an advanced generation of the cooler that is currently under development to provide cooling at 10K and less. This paper presents an overview of the current generation cooler with recent flight test results and details the current plans and development progress on the next generation TurboBrayton technology for future missions.

  4. Ab initio thermodynamic approach to identify mixed solid sorbents for CO 2 capture technology

    DOE PAGES

    Duan, Yuhua

    2015-10-15

    Because the current technologies for capturing CO 2 are still too energy intensive, new materials must be developed that can capture CO 2 reversibly with acceptable energy costs. At a given CO 2 pressure, the turnover temperature (T t) of the reaction of an individual solid that can capture CO 2 is fixed. Such T t may be outside the operating temperature range (ΔT o) for a practical capture technology. To adjust T t to fit the practical ΔT o, in this study, three scenarios of mixing schemes are explored by combining thermodynamic database mining with first principles density functionalmore » theory and phonon lattice dynamics calculations. Our calculated results demonstrate that by mixing different types of solids, it’s possible to shift T t to the range of practical operating temperature conditions. According to the requirements imposed by the pre- and post- combustion technologies and based on our calculated thermodynamic properties for the CO 2 capture reactions by the mixed solids of interest, we were able to identify the mixing ratios of two or more solids to form new sorbent materials for which lower capture energy costs are expected at the desired pressure and temperature conditions.« less

  5. QuEST: Qualifying Environmentally Sustainable Technologies. Volume 2

    NASA Technical Reports Server (NTRS)

    Brown, Christina (Editor)

    2007-01-01

    TEERM focuses its validation efforts on technologies that have shown promise in laboratory testing, but lack testing under realistic or field environment. Mature technologies have advantages over those that are still in the developmental stage such as being more likely to be transitioned into a working environment. One way TEERM begins to evaluate the suitability of technologies is through Technology Readiness Levels (TRLs). TRLs are a systematic metric/measurement system that supports assessments of the maturity of a particular technology and the consistent comparison of maturity between different types of technology. TEERM generally works on demonstrating/validating alternatives that fall within TRLs 5-9. In instances where a mature technology does not exist for a particular Agency application, TEERM works with technology development groups and programs such as NASA's Innovative Partnerships Program (IPP). The IPP's purpose is to identify and document available technologies in light of NASA's needs, evaluate and prioritize those technologies, and reach out to find new partners. All TEERM projects involve multiple partners. Partnering reduces duplication of effort that otherwise might occur if individuals worked their problems alone. Partnering also helps reduce individual contributors' shares of the total cost of technology validation. Through collaboration and financial commitment from project stakeholders and third-party sources, it is possible to fully fund expensive demonstration/validation efforts.

  6. Florida manatee avoidance technology: A pilot program by the Florida Fish and Wildlife Conservation Commission

    NASA Astrophysics Data System (ADS)

    Frisch, Katherine; Haubold, Elsa

    2003-10-01

    Since 1976, approximately 25% of the annual Florida manatee (Trichechus manatus latirostris) mortality has been attributed to collisions with watercraft. In 2001, the Florida Legislature appropriated $200,000 in funds for research projects using technological solutions to directly address the problem of collisions between manatees and watercraft. The Florida Fish & Wildlife Conservation Commission initially funded seven projects for the first two fiscal years. The selected proposals were designed to explore technology that had not previously been applied to the manatee/boat collision problem and included many acoustic concepts related to voice recognition, sonar, and an alerting device to be put on boats to warn manatees. The most promising results to date are from projects employing voice-recognition techniques to identify manatee vocalizations and warn boaters of the manatees' presence. Sonar technology, much like that used in fish finders, is promising but has met with regulatory problems regarding permitting and remains to be tested, as has the manatee-alerting device. The state of Florida found results of the initial years of funding compelling and plans to fund further manatee avoidance technology research in a continued effort to mitigate the problem of manatee/boat collisions.

  7. Gender Equity Expert Panel: Exemplary & Promising Gender Equity Programs, 2000.

    ERIC Educational Resources Information Center

    Department of Education, Washington, DC.

    The U.S. Department of Education developed the Gender Equity Expert Panel to identify promising and exemplary programs that promote gender equity in and through education. This panel of experts reviewed self-nominated programs to determine whether they met four criteria: evidence of success/effectiveness in promoting gender equity; quality of the…

  8. Promising Directions for Research Regarding Adult Education in Latin America.

    ERIC Educational Resources Information Center

    Knox, Alan B.

    Documents about adult education in Latin America at the Survey and Analysis Center of the Adult Education Association of the U.S.A. were reviewed to identify promising research directions. A theoretical framework for research should be developed and should include definitions of concepts and variables in different settings and identification of…

  9. iPAS: AES Flight System Technology Maturation for Human Spaceflight

    NASA Technical Reports Server (NTRS)

    Othon, William L.

    2014-01-01

    In order to realize the vision of expanding human presence in space, NASA will develop new technologies that can enable future crewed spacecraft to go far beyond Earth orbit. These technologies must be matured to the point that future project managers can accept the risk of incorporating them safely and effectively within integrated spacecraft systems, to satisfy very challenging mission requirements. The technologies must also be applied and managed within an operational context that includes both on-board crew and mission support on Earth. The Advanced Exploration Systems (AES) Program is one part of the NASA strategy to identify and develop key capabilities for human spaceflight, and mature them for future use. To support this initiative, the Integrated Power Avionics and Software (iPAS) environment has been developed that allows engineers, crew, and flight operators to mature promising technologies into applicable capabilities, and to assess the value of these capabilities within a space mission context. This paper describes the development of the integration environment to support technology maturation and risk reduction, and offers examples of technology and mission demonstrations executed to date.

  10. Technology tools to support reading in the digital age.

    PubMed

    Biancarosa, Gina; Griffiths, Gina G

    2012-01-01

    Advances in digital technologies are dramatically altering the texts and tools available to teachers and students. These technological advances have created excitement among many for their potential to be used as instructional tools for literacy education. Yet with the promise of these advances come issues that can exacerbate the literacy challenges identified in the other articles in this issue. In this article Gina Biancarosa and Gina Griffiths characterize how literacy demands have changed in the digital age and how challenges identified in other articles in the issue intersect with these new demands. Rather than seeing technology as something to be fit into an already crowded education agenda, Biancarosa and Griffiths argue that technology can be conceptualized as affording tools that teachers can deploy in their quest to create young readers who possess the higher levels of literacy skills and background knowledge demanded by today's information-based society. Biancarosa and Griffiths draw on research to highlight some of the ways technology has been used to build the skills and knowledge needed both by children who are learning to read and by those who have progressed to reading to learn. In their review of the research, Biancarosa and Griffiths focus on the hardware and software used to display and interface with digital text, or what they term e-reading technology. Drawing on studies of e-reading technology and computer technology more broadly, they also reflect on the very real, practical challenges to optimal use of e-reading technology. The authors conclude by presenting four recommendations to help schools and school systems meet some of the challenges that come with investing in e-reading technology: use only technologies that support Universal Design for Learning; choose evidence-based tools; provide technology users with systemic supports; and capitalize on the data capacities and volume of information that technology provides.

  11. Identifying new technologies that save energy and reduce costs to the Federal sector: The New Technology Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hunt, W.D.M.; Conover, D.R.; Stockmeyer, M.K.

    1995-11-01

    In 1990 the New Technology Demonstration Program (formerly the Test Bed Demonstration Program) was initiated by the US Department of Energy`s Office (DOE`s) of Federal Energy Management Programs with the purpose of accelerating the introduction of new technologies into the Federal sector. The program has since expanded into a multi-laboratory collaborative effort that evaluates new technologies and shares the results with the Federal design and procurement communities. These evaluations are performed on a collaborative basis which typically includes technology manufacturers, Federal facilities, utilities, trade associations, research institutes, and other in partnership with DOE. The end result is a range ofmore » effective technology transfer tools that provide operations and performance data on new technologies to Federal designers, building managers, and procurement officials. These tools assist in accelerating a technology`s Federal application and realizing reductions in energy consumption and costs.« less

  12. Innovating With Rehabilitation Technology in the Real World: Promises, Potentials, and Perspectives.

    PubMed

    Chua, Karen Sui Geok; Kuah, Christopher Wee Keong

    2017-10-01

    In this article, we discuss robotic-assisted therapy as an emerging and significant field of clinical rehabilitation and its value proposition for innovating rehabilitation clinical practice. Attempts to achieve integration among clinicians' practices and bioengineers' machines often generate new challenges and controversies. To date, the literature is indicative of a sizeable number and variety of robotic devices in the field of clinical rehabilitation, some are commercially available; however, large-scale clinical outcomes are less positive than expected. The following main themes related to integrating rehabilitation technology in real-world clinical practice will be discussed: the application of current evidence-based practice and knowledge in relation to treatment in the rehabilitation clinic, perspectives from rehabilitation professionals using robotic-aided therapy with regard to challenges, and strategies for problem solving. Lastly, we present innovation philosophies with regard to sustainability of clinical rehabilitation technologies.

  13. Promise and progress in environmental genomics: a status report on the applications of gene expression-based microarray studies in ecologically relevant fish species.

    PubMed

    Hook, S E

    2010-12-01

    The advent of any new technology is typically met with great excitement. So it was a few years ago, when the combination of advances in sequencing technology and the development of microarray technology made measurements of global gene expression in ecologically relevant species possible. Many of the review papers published around that time promised that these new technologies would revolutionize environmental biology as they had revolutionized medicine and related fields. A few years have passed since these technological advancements have been made, and the use of microarray studies in non-model fish species has been adopted in many laboratories internationally. Has the relatively widespread adoption of this technology really revolutionized the fields of environmental biology, including ecotoxicology, aquaculture and ecology, as promised? Or have these studies merely become a novelty and a potential distraction for scientists addressing environmentally relevant questions? In this review, the promises made in early review papers, in particular about the advances that the use of microarrays would enable, are summarized; these claims are compared to the results of recent studies to determine whether the forecasted changes have materialized. Some applications, as discussed in the paper, have been realized and have led to advances in their field, others are still under development. © 2010 CSIRO. Journal of Fish Biology © 2010 The Fisheries Society of the British Isles.

  14. Cryogenic Technology Development for Exploration Missions

    NASA Technical Reports Server (NTRS)

    Chato, David J.

    2007-01-01

    This paper reports the status and findings of different cryogenic technology research projects in support of the President s Vision for Space Exploration. The exploration systems architecture study is reviewed for cryogenic fluid management needs. It is shown that the exploration architecture is reliant on the cryogenic propellants of liquid hydrogen, liquid oxygen and liquid methane. Needs identified include: the key technologies of liquid acquisition devices, passive thermal and pressure control, low gravity mass gauging, prototype pressure vessel demonstration, active thermal control; as well as feed system testing, and Cryogenic Fluid Management integrated system demonstration. Then five NASA technology projects are reviewed to show how these needs are being addressed by technology research. Projects reviewed include: In-Space Cryogenic Propellant Depot; Experimentation for the Maturation of Deep Space Cryogenic Refueling Technology; Cryogenic Propellant Operations Demonstrator; Zero Boil-Off Technology Experiment; and Propulsion and Cryogenic Advanced Development. Advances are found in the areas of liquid acquisition of liquid oxygen, mass gauging of liquid oxygen via radio frequency techniques, computational modeling of thermal and pressure control, broad area cooling thermal control strategies, flight experiments for resolving low gravity issues of cryogenic fluid management. Promising results are also seen for Joule-Thomson pressure control devices in liquid oxygen and liquid methane and liquid acquisition of methane, although these findings are still preliminary.

  15. Telepsychiatry: Promise, potential, and challenges

    PubMed Central

    Malhotra, Savita; Chakrabarti, Subho; Shah, Ruchita

    2013-01-01

    Despite the high prevalence and potentially disabling consequences of mental disorders, specialized mental health services are extremely deficient, leading to the so-called ‘Mental Health Gap’. Moreover, the services are concentrated in the urban areas, further worsening the rural-urban and tertiary primary care divide. Strengthening of and expanding the existing human resources and infrastructure, and integrating mental health into primary care appear to be the two major solutions. However, both the strategies are riddled with logistic difficulties and have a long gestation period. In such a scenario, telepsychiatry or e-mental health, defined as the use of information and communication technology to provide or support psychiatric services across distances, appears to be a promising answer. Due to its enormous potential, a review of the existing literature becomes imperative. An extensive search of literature was carried out and has been presented to delineate the modes of communication, acceptability and satisfaction, reliability, outcomes, cost-effectiveness, and legal and ethical challenges related to telepsychiatry. Telepsychiatry has been applied for direct patient care (diagnosis and management), consultation, and training, education, and research purposes. Both real-time, live interaction (synchronous) and store–forward (asynchronous) types of technologies have been used for these purposes. A growing amount of literature shows that training, supervision, and consultation by specialists to primary care physicians through telepsychiatry has several advantages. In this background, we have further focused on the models of telepsychiatry best suited for India, considering that mental health care can be integrated into primary care and taken to the doorstep of patients in the community. PMID:23441027

  16. The promise of air cargo: System aspects and vehicle design

    NASA Technical Reports Server (NTRS)

    Whitehead, A. H., Jr.

    1976-01-01

    The current operation of the air cargo system is reviewed. An assessment of the future of air cargo is provided by: (1) analyzing statistics and trends, (2) by noting system problems and inefficiencies, (3) by analyzing characteristics of 'air eligible' commodities, and (4) by showing the promise of new technology for future cargo aircraft with significant improvements in costs and efficiency. The following topics are discussed: (1) air cargo demand forecasts; (2) economics of air cargo transport; (3) the integrated air cargo system; (4) evolution of airfreighter design; and (5) the span distributed load concept.

  17. Overview of existing cartilage repair technology.

    PubMed

    McNickle, Allison G; Provencher, Matthew T; Cole, Brian J

    2008-12-01

    Currently, autologous chondrocyte implantation and osteochondral grafting bridge the gap between palliation of cartilage injury and resurfacing via arthroplasty. Emerging technologies seek to advance first generation techniques and accomplish several goals including predictable outcomes, cost-effective technology, single-stage procedures, and creation of durable repair tissue. The biologic pipeline represents a variety of technologies including synthetics, scaffolds, cell therapy, and cell-infused matrices. Synthetic constructs, an alternative to biologic repair, resurface a focal chondral defect rather than the entire joint surface. Scaffolds are cell-free constructs designed as a biologic "net" to augment marrow stimulation techniques. Minced cartilage technology uses stabilized autologous or allogeneic fragments in 1-stage transplantation. Second and third generation cell-based methods include alternative membranes, chondrocyte seeding, and culturing onto scaffolds. Despite the promising early results of these products, significant technical obstacles remain along with unknown long-term durability. The vast array of developing technologies has exceptional promise and the potential to revolutionize the cartilage treatment algorithm within the next decade.

  18. Klamath Falls: High-Power Acoustic Well Stimulation Technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Black, Brian

    Acoustic well stimulation (AWS) technology uses high-power sonic waves from specific frequency spectra in an attempt to stimulate production in a damaged or low-production wellbore. AWS technology is one of the most promising technologies in the oil and gas industry, but it has proven difficult for the industry to develop an effective downhole prototype. This collaboration between Klamath Falls Inc. and the Rocky Mountain Oilfield Testing Center (RMOTC) included a series of tests using high-power ultrasonic tools to stimulate oil and gas production. Phase I testing was designed and implemented to verify tool functionality, power requirements, and capacity of high-powermore » AWS tools. The purpose of Phase II testing was to validate the production response of wells with marginal production rates to AWS stimulation and to capture and identify any changes in the downhole environment after tool deployment. This final report presents methodology and results.« less

  19. NASA/Goddard Thermal Technology Overview 2012

    NASA Technical Reports Server (NTRS)

    Butler, Dan; Swanson, Ted

    2012-01-01

    New Technology program is underway at NASA NASA/GSFC's primary mission of science satellite development is healthy and vibrant, although new missions are scarce Future mission applications promise to be thermally challenging Direct technology funding is still very restricted

  20. Promising Targets in Anti-cancer Drug Development: Recent Updates.

    PubMed

    Kumar, Bhupinder; Singh, Sandeep; Skvortsova, Ira; Kumar, Vinod

    2017-01-01

    Cancer is a multifactorial disease and its genesis and progression are extremely complex. The biggest problem in the anticancer drug development is acquiring of multidrug resistance and relapse. Classical chemotherapeutics directly target the DNA of the cell, while the contemporary anticancer drugs involve molecular-targeted therapy such as targeting the proteins possessing abnormal expression inside the cancer cells. Conventional strategies for the complete eradication of the cancer cells proved ineffective. Targeted chemotherapy was successful in certain malignancies however, the effectiveness has often been limited by drug resistance and side effects on normal tissues and cells. Since last few years, many promising drug targets have been identified for the effective treatment of cancer. The current review article describes some of these promising anticancer targets that include kinases, tubulin, cancer stem cells, monoclonal antibodies and vascular targeting agents. In addition, promising drug candidates under various phases of clinical trials are also described. Multi-acting drugs that simultaneously target different cancer cell signaling pathways may facilitate the process of effective anti-cancer drug development. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  1. Analytic Complexity and Challenges in Identifying Mixtures of Exposures Associated with Phenotypes in the Exposome Era.

    PubMed

    Patel, Chirag J

    2017-01-01

    Mixtures, or combinations and interactions between multiple environmental exposures, are hypothesized to be causally linked with disease and health-related phenotypes. Established and emerging molecular measurement technologies to assay the exposome , the comprehensive battery of exposures encountered from birth to death, promise a new way of identifying mixtures in disease in the epidemiological setting. In this opinion, we describe the analytic complexity and challenges in identifying mixtures associated with phenotype and disease. Existing and emerging machine-learning methods and data analytic approaches (e.g., "environment-wide association studies" [EWASs]), as well as large cohorts may enhance possibilities to identify mixtures of correlated exposures associated with phenotypes; however, the analytic complexity of identifying mixtures is immense. If the exposome concept is realized, new analytical methods and large sample sizes will be required to ascertain how mixtures are associated with disease. The author recommends documenting prevalent correlated exposures and replicated main effects prior to identifying mixtures.

  2. Hypersonic transport technology

    NASA Technical Reports Server (NTRS)

    Kirkham, F. S.; Hunt, J. L.

    1977-01-01

    The possibility of developing a hypersonic commercial transport (HST) for the early 21st century is explored in terms of potential performance characteristics and recent advances in propulsion and structures technology. Range-gross weight characteristics indicate that a 200 passenger, Mach 6 aircraft with a range of 9200 km (5000 n.mi.) would have a gross take-off weight not too different from that of current wide-body subsonic transports. The low cruise sonic boom overpressures generated by the HST opens the possibility of supersonic overland flight which, if permitted, would greatly increase the attractiveness of this type of aircraft. Recent advances in hypersonic propulsion systems and long-lived hypersonic aircraft structure are also discussed. The airframe-integrated scramjet and the actively-cooled airframe structure are identified as the most promising candidates for the HST and current approaches are described in some detail.

  3. Computers in the English Program: Promises and Pitfalls. New York State English Council Monograph.

    ERIC Educational Resources Information Center

    Chew, Charles R., Ed.

    Since an increasing number of English teachers are being asked to find a place for computers in the English program, this monograph focuses on issues connected to this technology. The first article sets the stage with a discussion of the power and potential of the computer. Other articles focus on the following topics: (1) promises and…

  4. Pediatric Multiple Organ Dysfunction Syndrome: Promising Therapies

    PubMed Central

    Doctor, Allan; Zimmerman, Jerry; Agus, Michael; Rajasekaran, Surender; Wardenburg, Juliane Bubeck; Fortenberry, James; Zajicek, Anne; Typpo, Katri

    2016-01-01

    Objective To describe the state of the science, identify knowledge gaps, and offer potential future research questions regarding promising therapies for children with multiple organ dysfunction syndrome (MODS) presented during the Eunice Kennedy Shriver National Institute of Child Health and Human Development Workshop on Pediatric Multiple Organ Dysfunction Syndrome (March 26-27, 2015). Data Sources Literature review, research data, and expert opinion. Study Selection Not applicable. Data Extraction Moderated by an expert from the field, issues relevant to the association of MODS with a variety of conditions were presented, discussed and debated with a focus on identifying knowledge gaps and research priorities. Data Synthesis Summary of presentations and discussion supported and supplemented by relevant literature. Conclusions Among critically ill children, MODS is relatively common and associated with significant morbidity and mortality. For outcomes to improve, effective therapies aimed at preventing and treating this condition must be discovered and rigorously evaluated. In this manuscript, a number of potential opportunities to enhance current care are highlighted including the need for a better understanding of the pharmacokinetics and pharmacodynamics of medications, the effect of early and optimized nutrition, and the impact of effective glucose control in the setting of MODS. Additionally, a handful of the promising therapies either currently being implemented or developed are described. These include extracorporeal therapies, anti-cytokine therapies, anti-toxin treatments, anti-oxidant approaches and multiple forms of exogenous steroids. For the field to advance, these and other therapies must be assessed in rigorous manner and implemented accordingly. PMID:28248836

  5. Information Technology and Educational Amnesia

    ERIC Educational Resources Information Center

    Winner, Langdon

    2009-01-01

    Waves of enthusiasm for technological innovations that promise to revitalize teaching and learning are at least a century old. Unfortunately, the record of accomplishment for the many varieties of hardware and software introduced into schools over the decades is remarkably thin. Today's promoters of technology in education tend to forget similar…

  6. New Technology and Information Explosion.

    ERIC Educational Resources Information Center

    Johns, David

    A flood of new electronic technologies promises to usher in the Information Age and alter economic and social structures. Telematics, a potent combination of telecommunications and computer technologies, could eventually bring huge volumes of information to great numbers of people by making large data bases accessible to computer terminals in…

  7. Key technologies for expeditions to Mars.

    NASA Astrophysics Data System (ADS)

    French, J. R., Jr.

    A round-trip manned Mars landing mission, while difficult, is within the realm of today's technology. However, better understood and more practical advanced technologies offer promising improvements in mass performance, and some also enhance certain aspects of self-reliance for manned missions.

  8. The promise of molecular epidemiology in defining the association between radiation and cancer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Neta, R.

    2000-07-01

    Molecular epidemiology involves the inclusion in epidemiologic studies of biologic measurements made at a genetic and molecular level and aims to improve the current knowledge of disease etiology and risk. One of the goals of molecular epidemiology studies of cancer is to determine the role of environmental and genetic factors in initiation and progression of malignancies and to use this knowledge to develop preventive strategies. This approach promises extraordinary opportunities for revolutionizing the practice of medicine and reducing risk. However, this will be accompanied by the need to address and resolve many challenges, such as ensuring the appropriate interpretation ofmore » molecular testing and resolving associated ethical, legal, and social issues. Traditional epidemiologic approaches determined that exposure to ionizing radiation poses significantly increased risk of leukemia and several other types of cancer. Such studies provided the basis for setting exposure standards to protect the public and the workforce from potentially adverse effects of ionizing radiation. These standards were set by using modeling approaches to extrapolate from the biological effects observed in high-dose radiation studies to predicted, but mostly immeasurable, effects at low radiation doses. It is anticipated that the addition of the molecular parameters to the population-based studies will help identify the genes and pathways characteristic of cancers due to radiation exposure of individuals, as well as identify susceptible or resistant subpopulations. In turn, the information about the molecular mechanisms should aid to improve risk assessment. While studies on radiogenic concerns are currently limited to only a few candidate genes, the exponential growth of scientific knowledge and technology promises expansion of knowledge about identity of participating genes and pathways in the future. This article is meant to provide an introductory overview of recent advances in

  9. Promising Fuel Cycle Options for R&D – Results, Insights, and Future Directions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wigeland, Roald Arnold

    2015-05-01

    The Fuel Cycle Options (FCO) campaign in the U.S. DOE Fuel Cycle Research & Development Program conducted a detailed evaluation and screening of nuclear fuel cycles. The process for this study was described at the 2014 ICAPP meeting. This paper reports on detailed insights and questions from the results of the study. The comprehensive study identified continuous recycle in fast reactors as the most promising option, using either U/Pu or U/TRU recycle, and potentially in combination with thermal reactors, as reported at the ICAPP 2014 meeting. This paper describes the examination of the results in detail that indicated that theremore » was essentially no difference in benefit between U/Pu and U/TRU recycle, prompting questions about the desirability of pursuing the more complex U/TRU approach given that the estimated greater challenges for development and deployment. The results will be reported from the current effort that further explores what, if any, benefits of TRU recycle (minor actinides in addition to plutonium recycle) may be in order to inform decisions on future R&D directions. The study also identified continuous recycle using thorium-based fuel cycles as potentially promising, in either fast or thermal systems, but with lesser benefit. Detailed examination of these results indicated that the lesser benefit was confined to only a few of the evaluation metrics, identifying the conditions under which thorium-based fuel cycles would be promising to pursue. For the most promising fuel cycles, the FCO is also conducting analyses on the potential transition to such fuel cycles to identify the issues, challenges, and the timing for critical decisions that would need to be made to avoid unnecessary delay in deployment, including investigation of issues such as the effects of a temporary lack of plutonium fuel resources or supporting infrastructure. These studies are placed in the context of an overall analysis approach designed to provide comprehensive

  10. New Technologies Promise Dramatic Increase In Capabilities of the Very Large Array

    NASA Astrophysics Data System (ADS)

    1996-06-01

    The National Science Foundation's Very Large Array (VLA) radio telescope in New Mexico is an exceedingly powerful scientific instrument, and has transformed many areas of astronomy in its more than 15 years of operation. It has been used by more astronomers and has produced more scientific papers than any other radio telescope. Though its position as one of the world's premier radio telescopes will remain unchallenged for a long time, new technologies could increase its scientific capabilities greater than tenfold. Details were presented today to the American Astronomical Society's meeting in Madison, Wisconsin. An enhanced VLA, incorporating state-of-the-art technologies, would provide scientists with a number of important, new capabilities, including detailed investigations of the physics of solar radio bursts; improved radar probes of planets, asteroids and comets; the ability to image protoplanetary disks around young stars; more rapid response and effective observations of transient events such as supernovae; new types of information about gas both within our own Galaxy and in other galaxies; and greatly improved ability to study clusters of galaxies and extremely distant objects in the Universe. In addition, the enhanced VLA will serve as an improved partner with the Very Long Baseline Array (VLBA), a continent-wide radio telescope, also part of the National Radio Astronomy Observatory (NRAO). "The VLA upgrade proposes an essentially new instrument, created from two existing instruments, with power and capability far exceeding that of either one alone," said Rick Perley, NRAO Project Scientist for the VLA Upgrade Project. "It builds on the existing staff and infrastructure and would hardly affect operations costs. In today's fiscal climate, this provides the benefit of a `new' instrument with outstanding scientific capability at the least cost," Perley added. The VLA was built in the 1970s and dedicated in 1980. At the time of its completion, it was a state

  11. New technologies emerge.

    PubMed

    Gray, S P

    1997-01-01

    Technology vendors continue to invent new devices, systems and processes to sell to the health care industry. Drugs, instruments and procedures continue to improve and address disease and injury treatment needs. In addition to these direct medical treatment innovations and enhancements, a number of new supporting systems and products have emerged. These support technologies hold significant promise for managers to make day-to-day execution of health care delivery more cost effective and customer friendly.

  12. Digital technology for treating and preventing mental disorders in low-income and middle-income countries: a narrative review of the literature.

    PubMed

    Naslund, John A; Aschbrenner, Kelly A; Araya, Ricardo; Marsch, Lisa A; Unützer, Jürgen; Patel, Vikram; Bartels, Stephen J

    2017-06-01

    Few individuals living with mental disorders around the globe have access to mental health care, yet most have access to a mobile phone. Digital technology holds promise for improving access to, and quality of, mental health care. We reviewed evidence on the use of mobile, online, and other remote technologies for treatment and prevention of mental disorders in low-income and middle-income countries. Of the 49 studies identified, most were preliminary evaluations of feasibility and acceptability. The findings were promising, showing the potential effectiveness of online, text-messaging, and telephone support interventions. We summarised the evaluations as: technology for supporting clinical care and educating health workers, mobile tools for facilitating diagnosis and detection of mental disorders, technologies for promoting treatment adherence and supporting recovery, online self-help programmes for individuals with mental disorders, and programmes for substance misuse prevention and treatment. Continued research is needed to rigorously evaluate effectiveness, assess costs, and carefully consider potential risks of digital technology interventions for mental disorders, while determining how emerging technologies might support the scale-up of mental health treatment and prevention efforts across low-resource settings. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Digital technology for treating and preventing mental disorders in low-income and middle-income countries: a narrative review of the literature

    PubMed Central

    Naslund, John A; Aschbrenner, Kelly A; Araya, Ricardo; Marsch, Lisa A; Unützer, Jürgen; Patel, Vikram; Bartels, Stephen J

    2017-01-01

    Few individuals living with mental disorders around the globe have access to mental health care, yet most have access to a mobile phone. Digital technology holds promise for improving access to, and quality of, mental health care. We reviewed evidence on the use of mobile, online, and other remote technologies for treatment and prevention of mental disorders in low-income and middle-income countries. Of the 49 studies identified, most were preliminary evaluations of feasibility and acceptability. The findings were promising, showing the potential effectiveness of online, text-messaging, and telephone support interventions. We summarised the evaluations as: technology for supporting clinical care and educating health workers, mobile tools for facilitating diagnosis and detection of mental disorders, technologies for promoting treatment adherence and supporting recovery, online self-help programmes for individuals with mental disorders, and programmes for substance misuse prevention and treatment. Continued research is needed to rigorously evaluate effectiveness, assess costs, and carefully consider potential risks of digital technology interventions for mental disorders, while determining how emerging technologies might support the scale-up of mental health treatment and prevention efforts across low-resource settings. PMID:28433615

  14. Allogeneic Cell Therapy Bioprocess Economics and Optimization: Single-Use Cell Expansion Technologies

    PubMed Central

    Simaria, Ana S; Hassan, Sally; Varadaraju, Hemanthram; Rowley, Jon; Warren, Kim; Vanek, Philip; Farid, Suzanne S

    2014-01-01

    For allogeneic cell therapies to reach their therapeutic potential, challenges related to achieving scalable and robust manufacturing processes will need to be addressed. A particular challenge is producing lot-sizes capable of meeting commercial demands of up to 109 cells/dose for large patient numbers due to the current limitations of expansion technologies. This article describes the application of a decisional tool to identify the most cost-effective expansion technologies for different scales of production as well as current gaps in the technology capabilities for allogeneic cell therapy manufacture. The tool integrates bioprocess economics with optimization to assess the economic competitiveness of planar and microcarrier-based cell expansion technologies. Visualization methods were used to identify the production scales where planar technologies will cease to be cost-effective and where microcarrier-based bioreactors become the only option. The tool outputs also predict that for the industry to be sustainable for high demand scenarios, significant increases will likely be needed in the performance capabilities of microcarrier-based systems. These data are presented using a technology S-curve as well as windows of operation to identify the combination of cell productivities and scale of single-use bioreactors required to meet future lot sizes. The modeling insights can be used to identify where future R&D investment should be focused to improve the performance of the most promising technologies so that they become a robust and scalable option that enables the cell therapy industry reach commercially relevant lot sizes. The tool outputs can facilitate decision-making very early on in development and be used to predict, and better manage, the risk of process changes needed as products proceed through the development pathway. Biotechnol. Bioeng. 2014;111: 69–83. © 2013 Wiley Periodicals, Inc. PMID:23893544

  15. Allogeneic cell therapy bioprocess economics and optimization: single-use cell expansion technologies.

    PubMed

    Simaria, Ana S; Hassan, Sally; Varadaraju, Hemanthram; Rowley, Jon; Warren, Kim; Vanek, Philip; Farid, Suzanne S

    2014-01-01

    For allogeneic cell therapies to reach their therapeutic potential, challenges related to achieving scalable and robust manufacturing processes will need to be addressed. A particular challenge is producing lot-sizes capable of meeting commercial demands of up to 10(9) cells/dose for large patient numbers due to the current limitations of expansion technologies. This article describes the application of a decisional tool to identify the most cost-effective expansion technologies for different scales of production as well as current gaps in the technology capabilities for allogeneic cell therapy manufacture. The tool integrates bioprocess economics with optimization to assess the economic competitiveness of planar and microcarrier-based cell expansion technologies. Visualization methods were used to identify the production scales where planar technologies will cease to be cost-effective and where microcarrier-based bioreactors become the only option. The tool outputs also predict that for the industry to be sustainable for high demand scenarios, significant increases will likely be needed in the performance capabilities of microcarrier-based systems. These data are presented using a technology S-curve as well as windows of operation to identify the combination of cell productivities and scale of single-use bioreactors required to meet future lot sizes. The modeling insights can be used to identify where future R&D investment should be focused to improve the performance of the most promising technologies so that they become a robust and scalable option that enables the cell therapy industry reach commercially relevant lot sizes. The tool outputs can facilitate decision-making very early on in development and be used to predict, and better manage, the risk of process changes needed as products proceed through the development pathway. © 2013 Wiley Periodicals, Inc.

  16. A Study of Future Communications Concepts and Technologies for the National Airspace System-Part I

    NASA Technical Reports Server (NTRS)

    Ponchak, Denise S.; Apaza, Rafael D.; Wichgers, Joel M.; Haynes, Brian; Roy, Aloke

    2013-01-01

    The National Aviation and Space Administration (NASA) Glenn Research Center (GRC) is investigating current and anticipated wireless communications concepts and technologies that the National Airspace System (NAS) may need in the next 50 years. NASA has awarded three NASA Research Announcements (NAR) studies with the objective to determine the most promising candidate technologies for air-to-air and air-to-ground data exchange and analyze their suitability in a post-NextGen NAS environment. This paper will present progress made in the studies and describe the communications challenges and opportunities that have been identified during the studies' first phase.

  17. A Study of Future Communications Concepts and Technologies for the National Airspace System - Part IV

    NASA Technical Reports Server (NTRS)

    Ponchak, Denise S.; Apaza, Rafael D.; Wichgers, Joel M.; Haynes, Brian; Roy, Aloke

    2015-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) is investigating current and anticipated wireless communications concepts and technologies that the National Airspace System (NAS) may need in the next 50 years. NASA has awarded three NASA Research Announcements (NAR) studies with the objective to determine the most promising candidate technologies for air-to-air and air-to-ground data exchange and analyze their suitability in a post-NextGen NAS environment. This paper will present the final results describing the communications challenges and opportunities that have been identified as part of the study.

  18. A Study of Future Communications Concepts and Technologies for the National Airspace System - Part II

    NASA Technical Reports Server (NTRS)

    Ponchak, Denise S.; Apaza, Rafael D.; Haynes, Brian; Wichgers, Joel M.; Roy, Aloke

    2014-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) is investigating current and anticipated wireless communications concepts and technologies that the National Airspace System (NAS) may need in the next 50 years. NASA has awarded three NASA Research Announcements (NAR) studies with the objective to determine the most promising candidate technologies for air-to-air and air-to-ground data exchange and analyze their suitability in a post-NextGen NAS environment. This paper will present progress made in the studies and describe the communications challenges and opportunities that have been identified during the studies' first year.

  19. Establishing confidence in CCV/ACT technology

    NASA Technical Reports Server (NTRS)

    Holloway, R. B.; Shomber, H. A.

    1976-01-01

    Despite significant advancements in controls configured vehicles/active controls technology (CCV/ACT) in the past decade, few applications of this promising technology have appeared in recent aircraft designs. The status of CCV/ACT is summarized, and some of the constraints which are retarding its wider application are described. Suggestions toward establishing an increased level of confidence in the technology are given.

  20. Whole organism high content screening identifies stimulators of pancreatic beta-cell proliferation.

    PubMed

    Tsuji, Naoki; Ninov, Nikolay; Delawary, Mina; Osman, Sahar; Roh, Alex S; Gut, Philipp; Stainier, Didier Y R

    2014-01-01

    Inducing beta-cell mass expansion in diabetic patients with the aim to restore glucose homeostasis is a promising therapeutic strategy. Although several in vitro studies have been carried out to identify modulators of beta-cell mass expansion, restoring endogenous beta-cell mass in vivo has yet to be achieved. To identify potential stimulators of beta-cell replication in vivo, we established transgenic zebrafish lines that monitor and allow the quantification of cell proliferation by using the fluorescent ubiquitylation-based cell cycle indicator (FUCCI) technology. Using these new reagents, we performed an unbiased chemical screen, and identified 20 small molecules that markedly increased beta-cell proliferation in vivo. Importantly, these structurally distinct molecules, which include clinically-approved drugs, modulate three specific signaling pathways: serotonin, retinoic acid and glucocorticoids, showing the high sensitivity and robustness of our screen. Notably, two drug classes, retinoic acid and glucocorticoids, also promoted beta-cell regeneration after beta-cell ablation. Thus, this study establishes a proof of principle for a high-throughput small molecule-screen for beta-cell proliferation in vivo, and identified compounds that stimulate beta-cell proliferation and regeneration.

  1. Promising Practices in Citywide Afterschool Initiatives. CityWorks: Focus on Infrastructure.

    ERIC Educational Resources Information Center

    Hall, Georgia

    This brief is the first in a series featuring promising practices in city-wide after-school initiatives, with a focus at the infrastructure level, focusing on the infrastructure representing the underlying elements or framework that hold a system or initiative together. The brief identifies practices to support the public relations function and…

  2. Role of geospatial technology in identifying natural habitat of malarial vectors in South Andaman, India.

    PubMed

    Shankar, Shiva; Agrawal, Deepak Kumar

    2016-03-01

    Malaria is a serious disease which has repeatedly threatened Andaman, an island territory of India. Uncharted dense vegetation and inaccessibility are the salient features of the area and the major areas are covered by remotely sensed data to identify the malaria vector's natural habitat. The present investigation appraises the role of geospatial technologies in identifying the natural habitat of malarial vectors. The base map was prepared from Survey of India's toposheets, the landuse map was prepared from indices techniques like normalised difference vegetation index (NDVI), normalised difference water index (NDWI), modified normalised difference water index (MNDWI), normalised difference pond index (NDPI), and normalized difference turbidity index (NDTI) in conjugation with visual interpretation. The soil moisture content map was reproduced from the soil atlas of Andaman and Nicobar Islands followed by generation of an aspect profile from ASTER-GDEM satellite data. Both the landuse map and aspect profile were validated for accuracy in the field. A weighted overlay analysis of the classes like landuse, soil moisture and aspect profile of the study area resulted in identification of the potential natural habitat map of malaria vector surrounding the areas of Tushnabad, Garacharma, Manglutan, Chouldari, Ferrargunj and Wimberlygunj hamlets. The natural habitat of malaria vector indicated that Tushnabad, Garacharma, Manglutan, Chouldari, Ferrargunj and Wimberlygunj hamlets are within the proximity of 2.5 km from the prime habitat location with more number of malaria positive cases. Also these hamlets are surrounded by dense evergreen forest and the land surface is draped by clay loam and clay soil texture exhibiting high soil moisture content warranting high rates of survival and proliferation of the vector ensuring resurgence of malaria every year. It is thus concluded that application of geospatial technologies plays an important role in identifying the natural

  3. Paving the Way to Successful Implementation: Identifying Key Barriers to Use of Technology-Based Therapeutic Tools for Behavioral Health Care.

    PubMed

    Ramsey, Alex; Lord, Sarah; Torrey, John; Marsch, Lisa; Lardiere, Michael

    2016-01-01

    This study aimed to identify barriers to use of technology for behavioral health care from the perspective of care decision makers at community behavioral health organizations. As part of a larger survey of technology readiness, 260 care decision makers completed an open-ended question about perceived barriers to use of technology. Using the Consolidated Framework for Implementation Research (CFIR), qualitative analyses yielded barrier themes related to characteristics of technology (e.g., cost and privacy), potential end users (e.g., technology literacy and attitudes about technology), organization structure and climate (e.g., budget and infrastructure), and factors external to organizations (e.g., broadband accessibility and reimbursement policies). Number of reported barriers was higher among respondents representing agencies with lower annual budgets and smaller client bases relative to higher budget, larger clientele organizations. Individual barriers were differentially associated with budget, size of client base, and geographic location. Results are discussed in light of implementation science frameworks and proactive strategies to address perceived obstacles to adoption and use of technology-based behavioral health tools.

  4. Paving the Way to Successful Implementation: Identifying Key Barriers to Use of Technology-Based Therapeutic Tools for Behavioral Health Care

    PubMed Central

    Ramsey, Alex; Lord, Sarah; Torrey, John; Marsch, Lisa; Lardiere, Michael

    2014-01-01

    This study aimed to identify barriers to use of technology for behavioral health care from the perspective of care decision-makers at community behavioral health organizations. As part of a larger survey of technology readiness, 260 care decision-makers completed an open-ended question about perceived barriers to use of technology. Using the Consolidated Framework for Implementation Research (CFIR), qualitative analyses yielded barrier themes related to characteristics of technology (e.g., cost, privacy), potential end-users (e.g., technology literacy, attitudes about technology), organization structure and climate (e.g., budget, infrastructure), and factors external to organizations (e.g., broadband accessibility, reimbursement policies). Number of reported barriers was higher among respondents representing agencies with lower annual budgets and smaller client bases relative to higher budget, larger clientele organizations. Individual barriers were differentially associated with budget, size of client base, and geographic location. Results are discussed in light of implementation science frameworks and proactive strategies to address perceived obstacles to adoption and use of technology-based behavioral health tools. PMID:25192755

  5. Evaluation of promising technologies for soil salinity amelioration in Timpaki (Crete): a participatory approach

    NASA Astrophysics Data System (ADS)

    Panagea, I. S.; Daliakopoulos, I. N.; Tsanis, I. K.; Schwilch, G.

    2016-02-01

    Soil salinity management can be complex, expensive, and time demanding, especially in arid and semi-arid regions. Besides taking no action, possible management strategies include amelioration and adaptation measures. Here we apply the World Overview of Conservation Approaches and Technologies (WOCAT) framework for the systematic analysis and evaluation and selection of soil salinisation amelioration technologies in close collaboration with stakeholders. The participatory approach is applied in the RECARE (Preventing and Remediating degradation of soils in Europe through Land Care) project case study of Timpaki, a semi-arid region in south-central Crete (Greece) where the main land use is horticulture in greenhouses irrigated by groundwater. Excessive groundwater abstractions have resulted in a drop of the groundwater level in the coastal part of the aquifer, thus leading to seawater intrusion and in turn to soil salinisation. The documented technologies are evaluated for their impacts on ecosystem services, cost, and input requirements using a participatory approach and field evaluations. Results show that technologies which promote maintaining existing crop types while enhancing productivity and decreasing soil salinity are preferred by the stakeholders. The evaluation concludes that rainwater harvesting is the optimal solution for direct soil salinity mitigation, as it addresses a wider range of ecosystem and human well-being benefits. Nevertheless, this merit is offset by poor financial motivation making agronomic measures more attractive to users.

  6. The first step in the development of text mining technology for cancer risk assessment: identifying and organizing scientific evidence in risk assessment literature

    PubMed Central

    Korhonen, Anna; Silins, Ilona; Sun, Lin; Stenius, Ulla

    2009-01-01

    Background One of the most neglected areas of biomedical Text Mining (TM) is the development of systems based on carefully assessed user needs. We have recently investigated the user needs of an important task yet to be tackled by TM -- Cancer Risk Assessment (CRA). Here we take the first step towards the development of TM technology for the task: identifying and organizing the scientific evidence required for CRA in a taxonomy which is capable of supporting extensive data gathering from biomedical literature. Results The taxonomy is based on expert annotation of 1297 abstracts downloaded from relevant PubMed journals. It classifies 1742 unique keywords found in the corpus to 48 classes which specify core evidence required for CRA. We report promising results with inter-annotator agreement tests and automatic classification of PubMed abstracts to taxonomy classes. A simple user test is also reported in a near real-world CRA scenario which demonstrates along with other evaluation that the resources we have built are well-defined, accurate, and applicable in practice. Conclusion We present our annotation guidelines and a tool which we have designed for expert annotation of PubMed abstracts. A corpus annotated for keywords and document relevance is also presented, along with the taxonomy which organizes the keywords into classes defining core evidence for CRA. As demonstrated by the evaluation, the materials we have constructed provide a good basis for classification of CRA literature along multiple dimensions. They can support current manual CRA as well as facilitate the development of an approach based on TM. We discuss extending the taxonomy further via manual and machine learning approaches and the subsequent steps required to develop TM technology for the needs of CRA. PMID:19772619

  7. Technology Integration Barriers: Urban School Mathematics Teachers Perspectives

    ERIC Educational Resources Information Center

    Wachira, Patrick; Keengwe, Jared

    2011-01-01

    Despite the promise of technology in education, many practicing teachers face several challenges when trying to effectively integrate technology into their classroom instruction. Additionally, while national statistics cite a remarkable improvement in access to computer technology tools in schools, teacher surveys show consistent declines in the…

  8. Managed access technology to combat contraband cell phones in prison: Findings from a process evaluation.

    PubMed

    Grommon, Eric

    2018-02-01

    Cell phones in correctional facilities have emerged as one of the most pervasive forms of modern contraband. This issue has been identified as a top priority for many correctional administrators in the United States. Managed access, a technology that utilizes cellular signals to capture transmissions from contraband phones, has received notable attention as a promising tool to combat this problem. However, this technology has received little evaluative attention. The present study offers a foundational process evaluation and draws upon output measures and stakeholder interviews to identify salient operational challenges and subsequent lessons learned about implementing and maintaining a managed access system. Findings suggest that while managed access captures large volumes of contraband cellular transmissions, the technology requires significant implementation planning, personnel support, and complex partnerships with commercial cellular carriers. Lessons learned provide guidance for practitioners to navigate these challenges and for scholars to improve future evaluations of managed access. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. A FRET Biosensor for ROCK Based on a Consensus Substrate Sequence Identified by KISS Technology.

    PubMed

    Li, Chunjie; Imanishi, Ayako; Komatsu, Naoki; Terai, Kenta; Amano, Mutsuki; Kaibuchi, Kozo; Matsuda, Michiyuki

    2017-01-11

    Genetically-encoded biosensors based on Förster/fluorescence resonance energy transfer (FRET) are versatile tools for studying the spatio-temporal regulation of signaling molecules within not only the cells but also tissues. Perhaps the hardest task in the development of a FRET biosensor for protein kinases is to identify the kinase-specific substrate peptide to be used in the FRET biosensor. To solve this problem, we took advantage of kinase-interacting substrate screening (KISS) technology, which deduces a consensus substrate sequence for the protein kinase of interest. Here, we show that a consensus substrate sequence for ROCK identified by KISS yielded a FRET biosensor for ROCK, named Eevee-ROCK, with high sensitivity and specificity. By treating HeLa cells with inhibitors or siRNAs against ROCK, we show that a substantial part of the basal FRET signal of Eevee-ROCK was derived from the activities of ROCK1 and ROCK2. Eevee-ROCK readily detected ROCK activation by epidermal growth factor, lysophosphatidic acid, and serum. When cells stably-expressing Eevee-ROCK were time-lapse imaged for three days, ROCK activity was found to increase after the completion of cytokinesis, concomitant with the spreading of cells. Eevee-ROCK also revealed a gradual increase in ROCK activity during apoptosis. Thus, Eevee-ROCK, which was developed from a substrate sequence predicted by the KISS technology, will pave the way to a better understanding of the function of ROCK in a physiological context.

  10. Hot Technologies for Education: What's Happening Now and Later?

    ERIC Educational Resources Information Center

    National Middle School Association (NJ1), 2006

    2006-01-01

    The Consortium for School Networking's report, "Hot Technologies for K-12 Schools: The 2005 Guide for Technology Decision Makers," discusses some of the technologies that are likely to be tomorrow's "must-have" tools in schools. Perhaps the greatest promise of emerging technologies is their potential to transform learning.…

  11. Lost and misplaced items and assistive devices in nursing homes: Identifying problems and technological opportunities through participatory design research.

    PubMed

    Oude Weernink, C E; Sweegers, L; Relou, L; van der Zijpp, T J; van Hoof, J

    2018-02-06

    Modern healthcare, including nursing home care, goes together with the use of technologies to support treatment, the provision of care and daily activities. The challenges concerning the implementation of such technologies are numerous. One of these emerging technologies are location technologies (RTLS or Real-Time Location Systems). that can be utilized in the nursing home for monitoring the use and location of assets. This paper describes a participatory design study of RTLS based on context mapping, conducted in two nursing home organizations. Rather than investigating the technological possibilities, this study investigates the needs and wishes from the perspective of the care professional. The study identified semantic themes that relate to the practicalities of lost and misplaced items in the nursing home, as well as latent themes that cover the wishes regarding technology in the nursing homes. The organizational culture and building typology may play a role in losing items. The participants in this study indicated that RTLS can provide a solution to some of the challenges that they encounter in the workplace. However, the implementation of new technologies should be done with care and should be integrated into existing ICT systems in order to minimize additional training and posing a burden on the workload.

  12. Lost and misplaced items and assistive devices in nursing homes: Identifying problems and technological opportunities through participatory design research

    PubMed Central

    Oude Weernink, C.E.; Sweegers, L.; Relou, L.; van der Zijpp, T.J.; van Hoof, J.

    2018-01-01

    INTRODUCTION: Modern healthcare, including nursing home care, goes together with the use of technologies to support treatment, the provision of care and daily activities. The challenges concerning the implementation of such technologies are numerous. One of these emerging technologies are location technologies (RTLS or Real-Time Location Systems). that can be utilized in the nursing home for monitoring the use and location of assets. METHODOLOGY: This paper describes a participatory design study of RTLS based on context mapping, conducted in two nursing home organizations. Rather than investigating the technological possibilities, this study investigates the needs and wishes from the perspective of the care professional. RESULTS: The study identified semantic themes that relate to the practicalities of lost and misplaced items in the nursing home, as well as latent themes that cover the wishes regarding technology in the nursing homes. The organizational culture and building typology may play a role in losing items. CONCLUSION: The participants in this study indicated that RTLS can provide a solution to some of the challenges that they encounter in the workplace. However, the implementation of new technologies should be done with care and should be integrated into existing ICT systems in order to minimize additional training and posing a burden on the workload. PMID:29527110

  13. Promising Practices in Small High Schools. A Report of 15 Northwest Projects.

    ERIC Educational Resources Information Center

    Northwest Regional Educational Lab., Portland, OR.

    Promising methods utilized in small rural high schools to provide a wider range of experiences for students are identified and described. Programs reported on include the Arctic Nursing Program, Career Research Program, Contractual Study Program, Eye-opening Experience, Field Experience Program, Guitar and Folk Music Program, Individualized…

  14. Incorporating advanced EMI technologies in operational munitions characterization surveys

    NASA Astrophysics Data System (ADS)

    Miller, Jonathan S.; Shubiditze, Fridon; Pasion, Leonard; Schultz, Gregory; Chung, Heesoo

    2011-06-01

    The presence of unexploded ordnance (UXO), discarded military munitions (DMM), and munitions constituents (MC) at both active and formerly used defense sites (FUDS) has created a necessity for production-level efforts to remove these munitions and explosives of concern (MEC). Ordnance and explosives (OE) and UXO removal operations typically employ electromagnetic induction (EMI) or magnetometer surveys to identify potential MEC hazards in previously determined areas of interest. A major cost factor in these operations is the significant allocation of resources for the excavation of harmless objects associated with fragmentation, scrap, or geological clutter. Recent advances in classification and discrimination methodologies, as well as the development of sensor technologies that fully exploit physics-based analysis, have demonstrated promise for significantly reducing the false alarm rate due to MEC related clutter. This paper identifies some of the considerations for and the challenges associated with implementing these discrimination methodologies and advanced sensor technologies in production-level surveys. Specifically, we evaluate the implications of deploying an advanced multi-axis EMI sensor at a variety of MEC sites, the discrimination methodologies that leverage the data produced by this sensor, and the potential for productivity increase that could be realized by incorporating this advanced technology as part of production protocol.

  15. Distress detection, location, and communications using advanced space technology

    NASA Technical Reports Server (NTRS)

    Sivertson, W. E., Jr.

    1977-01-01

    This paper briefly introduces a concept for low-cost, global, day-night, all-weather disaster warning and assistance. Evolving, advanced space technology with passive radio frequency reflectors in conjunction with an imaging synthetic aperture radar is employed to detect, identify, locate, and provide passive communication with earth users in distress. This concept evolved from a broad NASA research on new global search and rescue techniques. Appropriate airborne radar test results from this research are reviewed and related to potential disaster applications. The analysis indicates the approach has promise for disaster communications relative to floods, droughts, earthquakes, volcanic eruptions, and severe storms.

  16. Advanced supersonic technology and its implications for the future

    NASA Technical Reports Server (NTRS)

    Driver, C.

    1979-01-01

    A brief overview of the NASA Supersonic Cruise Research (SCR) program is presented. The SCR program has identified significant improvements in the areas of aerodynamics, structures, propulsion, noise reduction, takeoff and landing procedures, and advanced configuration concepts. These improvements tend to overcome most of the problems which led to the cancellation of the National SST program. They offer the promise of an advanced SST family of aircraft which are environmentally acceptable, have flexible range-payload capability, and are economically viable. The areas of technology addressed by the SCR program have direct application to advanced military aircraft and to supersonic executive aircraft.

  17. Managing Diabetes: New Technologies Can Make It Easier

    MedlinePlus

    ... people with diabetes and their families.” Help From Technology NIH funded-scientists are testing promising technologies to ... your health care provider about your options. Related Stories Are Proteins in Formula Linked to Type 1 ...

  18. Promises and challenges in solid-state lighting

    NASA Astrophysics Data System (ADS)

    Schubert, Fred

    2010-03-01

    Lighting technologies based on semiconductor light-emitting diodes (LEDs) offer unprecedented promises that include three major benefits: (i) Gigantic energy savings enabled by efficient conversion of electrical energy to optical energy; (ii) Substantial positive contributions to sustainability through reduced emissions of global-warming gases, acid-rain gases, and toxic substances such as mercury; and (iii) The creation of new paradigms in lighting driven by the unique controllability of solid-state lighting sources. Due to the powerful nature of these benefits, the transition from conventional lighting sources to solid-state lighting is virtually assured. This presentation will illustrate the new world of lighting and illustrate the pervasive changes to be expected in lighting, displays, communications, and biotechnology. The presentation will also address the formidable challenges that must be addressed to continue the further advancement of solid-state lighting technology. These challenges offer opportunities for research and innovation. Specific challenges include light management, carrier transport, and optical design. We will present some innovative approaches in order to solve known technical challenges faced by solid-state lighting. These approaches include the demonstration and use of new optical thin-film materials with a continuously tunable refractive index. These approaches also include the use of polarization-matched structures that reduce the polarization fields in GaInN LEDs and the hotly debated efficiency droop, that is, the decreasing LED efficiency at high currents.

  19. Technology and Economics, Inc. Technology Application Team

    NASA Technical Reports Server (NTRS)

    Ballard, T.; Macfadyen, D. J.

    1981-01-01

    Technology + Economics, Inc. (T+E), under contract to the NASA Headquarters Technology Transfer Division, operates a Technology Applications Team (TATeam) to assist in the transfer of NASA-developed aerospace technology. T+E's specific areas of interest are selected urban needs at the local, county, and state levels. T+E contacts users and user agencies at the local, state, and county levels to assist in identifying significant urban needs amenable to potential applications of aerospace technology. Once viable urban needs have been identified in this manner, or through independent research, T+E searches the NASA technology database for technology and/or expertise applicable to the problem. Activities currently under way concerning potential aerospace applications are discussed.

  20. Overview study of Space Power Technologies for the advanced energetics program. [spacecraft

    NASA Technical Reports Server (NTRS)

    Taussig, R.; Gross, S.; Millner, A.; Neugebauer, M.; Phillips, W.; Powell, J.; Schmidt, E.; Wolf, M.; Woodcock, G.

    1981-01-01

    Space power technologies are reviewed to determine the state-of-the-art and to identify advanced or novel concepts which promise large increases in performance. The potential for incresed performance is judged relative to benchmarks based on technologies which have been flight tested. Space power technology concepts selected for their potentially high performance are prioritized in a list of R & D topical recommendations for the NASA program on Advanced Energetics. The technology categories studied are solar collection, nuclear power sources, energy conversion, energy storage, power transmission, and power processing. The emphasis is on electric power generation in space for satellite on board electric power, for electric propulsion, or for beamed power to spacecraft. Generic mission categories such as low Earth orbit missions and geosynchronous orbit missions are used to distinguish general requirements placed on the performance of power conversion technology. Each space power technology is judged on its own merits without reference to specific missions or power systems. Recommendations include 31 space power concepts which span the entire collection of technology categories studied and represent the critical technologies needed for higher power, lighter weight, more efficient power conversion in space.

  1. Technology Solutions | Distributed Generation Interconnection Collaborative

    Science.gov Websites

    technologies, both hardware and software, can support the wider adoption of distributed generation on the grid . As the penetration of distributed-generation photovoltaics (DGPV) has risen rapidly in recent years posed by high penetrations of distributed PV. Other promising technologies include new utility software

  2. PROMISE: Maryland's Alliance for Graduate Education and the Professoriate enhances recruitment and retention of underrepresented minority graduate students.

    PubMed

    Tull, Renetta G; Rutledge, Janet C; Carter, Frances D; Warnick, Jordan E

    2012-11-01

    PROMISE: Maryland's Alliance for Graduate Education and the Professoriate (AGEP), sponsored by the National Science Foundation, is a consortium that is designed to increase the numbers of underrepresented minority (URM) PhDs in science, technology, engineering, and mathematics fields who will pursue academic careers. A strength of PROMISE is its alliance infrastructure that connects URM graduate students on different campuses through centralized programming for the three research universities in Maryland: the University of Maryland Baltimore County (the lead institution in the alliance), the University of Maryland College Park, and the University of Maryland Baltimore (UMB). PROMISE initiatives cover graduate student recruitment, retention, community building, PhD completion, and transition to careers.Although it is not a fellowship, PROMISE offers professional development and skill-building programs that provide academic and personal support for URM students on all three campuses. PROMISE on UMB's campus includes the School of Medicine, which sponsors tricampus programs that promote health and wellness to accompany traditional professional development programs. PROMISE uniquely and atypically includes a medical school within its alliance. The PROMISE programs serve as interventions that reduce isolation and facilitate degree completion among diverse students on each campus. This article describes details of the PROMISE AGEP and presents suggestions for replicating professional development programs for URMs in biomedical, MD/master's, and MD/PhD programs on other campuses.

  3. Finding the Needle in the Haystack-the Use of Microfluidic Droplet Technology to Identify Vitamin-Secreting Lactic Acid Bacteria.

    PubMed

    Chen, Jun; Vestergaard, Mike; Jensen, Thomas Glasdam; Shen, Jing; Dufva, Martin; Solem, Christian; Jensen, Peter Ruhdal

    2017-05-30

    Efficient screening technologies aim to reduce both the time and the cost required for identifying rare mutants possessing a phenotype of interest in a mutagenized population. In this study, we combined a mild mutagenesis strategy with high-throughput screening based on microfluidic droplet technology to identify Lactococcus lactis variants secreting vitamin B 2 (riboflavin). Initially, we used a roseoflavin-resistant mutant of L. lactis strain MG1363, JC017, which secreted low levels of riboflavin. By using fluorescence-activated droplet sorting, several mutants that secreted riboflavin more efficiently than JC017 were readily isolated from the mutagenesis library. The screening was highly efficient, and candidates with as few as 1.6 mutations per million base pairs (Mbp) were isolated. The genetic characterization revealed that riboflavin production was triggered by mutations inhibiting purine biosynthesis, which is surprising since the purine nucleotide GTP is a riboflavin precursor. Purine starvation in the mutants induced overexpression of the riboflavin biosynthesis cluster ribABGH When the purine starvation was relieved by purine supplementation in the growth medium, the outcome was an immediate downregulation of the riboflavin biosynthesis cluster and a reduction in riboflavin production. Finally, by applying the new isolates in milk fermentation, the riboflavin content of milk (0.99 mg/liter) was improved to 2.81 mg/liter, compared with 0.66 mg/liter and 1.51 mg/liter by using the wild-type strain and the original roseoflavin-resistant mutant JC017, respectively. The results obtained demonstrate how powerful classical mutagenesis can be when combined with droplet-based microfluidic screening technology for obtaining microorganisms with useful attributes. IMPORTANCE The food industry prefers to use classical approaches, e.g., random mutagenesis followed by screening, to improve microorganisms used in food production, as the use of recombinant DNA

  4. Pharmacogenomic technologies: a necessary "luxury" for better global public health?

    PubMed Central

    2011-01-01

    Background Pharmacogenomic technologies aim to redirect drug development to increase safety and efficacy of individual care. There is much hope that their implementation in the drug development process will help respond to population health needs, particularly in developing countries. However, there is also fear that novel pharmacogenomic drugs will remain too costly, be designed for the needs of the wealthy nations, and so constitute an unnecessary "luxury" for most populations. In this paper, we analyse the promise that pharmacogenomic technologies hold for improving global public health and identify strategies and challenges associated with their implementation. Discussion This paper evaluates the capacity of pharmacogenomic technologies to meet six criteria described by the University of Toronto Joint Centre for Bioethics group: 1) impact of the technology, 2) technology appropriateness, 3) capacity to address local burdens, 4) feasibility to be implemented in reasonable time, 5) capacity to reduce the knowledge gap, and 6) capacity for indirect benefits. We argue that the implementation of pharmacogenomic technologies in the drug development process can positively impact population health. However, this positive impact depends on how and for which purposes the technologies are used. We discuss the potential of these technologies to stimulate drug discovery in the case of rare (orphan diseases) or neglected diseases, but also to reduce acute adverse drug reactions in infectious disease treatment and prevention, which promises to improve global public health. Conclusions The implementation of pharmacogenomic technologies may lead to the development of drugs that appear to be a "luxury" for populations in need of numerous interventions that are known to have a demonstrable impact on population health (e.g., secure access to potable water, reduction of social inequities, health education). However, our analysis shows that pharmacogenomic technologies do have the

  5. Coalitional game theory as a promising approach to identify candidate autism genes.

    PubMed

    Gupta, Anika; Sun, Min Woo; Paskov, Kelley Marie; Stockham, Nate Tyler; Jung, Jae-Yoon; Wall, Dennis Paul

    2018-01-01

    Despite mounting evidence for the strong role of genetics in the phenotypic manifestation of Autism Spectrum Disorder (ASD), the specific genes responsible for the variable forms of ASD remain undefined. ASD may be best explained by a combinatorial genetic model with varying epistatic interactions across many small effect mutations. Coalitional or cooperative game theory is a technique that studies the combined effects of groups of players, known as coalitions, seeking to identify players who tend to improve the performance--the relationship to a specific disease phenotype--of any coalition they join. This method has been previously shown to boost biologically informative signal in gene expression data but to-date has not been applied to the search for cooperative mutations among putative ASD genes. We describe our approach to highlight genes relevant to ASD using coalitional game theory on alteration data of 1,965 fully sequenced genomes from 756 multiplex families. Alterations were encoded into binary matrices for ASD (case) and unaffected (control) samples, indicating likely gene-disrupting, inherited mutations in altered genes. To determine individual gene contributions given an ASD phenotype, a "player" metric, referred to as the Shapley value, was calculated for each gene in the case and control cohorts. Sixty seven genes were found to have significantly elevated player scores and likely represent significant contributors to the genetic coordination underlying ASD. Using network and cross-study analysis, we found that these genes are involved in biological pathways known to be affected in the autism cases and that a subset directly interact with several genes known to have strong associations to autism. These findings suggest that coalitional game theory can be applied to large-scale genomic data to identify hidden yet influential players in complex polygenic disorders such as autism.

  6. Big data in healthcare - the promises, challenges and opportunities from a research perspective: A case study with a model database.

    PubMed

    Adibuzzaman, Mohammad; DeLaurentis, Poching; Hill, Jennifer; Benneyworth, Brian D

    2017-01-01

    Recent advances in data collection during routine health care in the form of Electronic Health Records (EHR), medical device data (e.g., infusion pump informatics, physiological monitoring data, and insurance claims data, among others, as well as biological and experimental data, have created tremendous opportunities for biological discoveries for clinical application. However, even with all the advancement in technologies and their promises for discoveries, very few research findings have been translated to clinical knowledge, or more importantly, to clinical practice. In this paper, we identify and present the initial work addressing the relevant challenges in three broad categories: data, accessibility, and translation. These issues are discussed in the context of a widely used detailed database from an intensive care unit, Medical Information Mart for Intensive Care (MIMIC III) database.

  7. FMCSA’s advanced system testing utilizing a data acquisition system on the highways (FAST DASH) safety technology evaluation project #2 : technology brief.

    DOT National Transportation Integrated Search

    2016-11-01

    The Federal Motor Carrier Safety Administration (FMCSA) established the FAST DASH program to perform efficient independent evaluations of promising safety technologies aimed at commercial vehicle operations. In this second FAST DASH safety technology...

  8. New technologies for information retrieval to achieve situational awareness and higher patient safety in the surgical operating room: the MRI institutional approach and review of the literature.

    PubMed

    Kranzfelder, Michael; Schneider, Armin; Gillen, Sonja; Feussner, Hubertus

    2011-03-01

    Technical progress in the operating room (OR) increases constantly, but advanced techniques for error prevention are lacking. It has been the vision to create intelligent OR systems ("autopilot") that not only collect intraoperative data but also interpret whether the course of the operation is normal or deviating from the schedule ("situation awareness"), to recommend the adequate next steps of the intervention, and to identify imminent risky situations. Recently introduced technologies in health care for real-time data acquisition (bar code, radiofrequency identification [RFID], voice and emotion recognition) may have the potential to meet these demands. This report aims to identify, based on the authors' institutional experience and a review of the literature (MEDLINE search 2000-2010), which technologies are currently most promising for providing the required data and to describe their fields of application and potential limitations. Retrieval of information on the functional state of the peripheral devices in the OR is technically feasible by continuous sensor-based data acquisition and online analysis. Using bar code technologies, automatic instrument identification seems conceivable, with information given about the actual part of the procedure and indication of any change in the routine workflow. The dynamics of human activities also comprise key information. A promising technology for continuous personnel tracking is data acquisition with RFID. Emotional data capture and analysis in the OR are difficult. Although technically feasible, nonverbal emotion recognition is difficult to assess. In contrast, emotion recognition by speech seems to be a promising technology for further workflow prediction. The presented technologies are a first step to achieving an increased situational awareness in the OR. However, workflow definition in surgery is feasible only if the procedure is standardized, the peculiarities of the individual patient are taken into account

  9. Image is more than a uniform: the promise of assurance.

    PubMed

    Wocial, Lucia D; Sego, Kelly; Rager, Carrie; Laubersheimer, Shellee; Everett, Linda Q

    2014-05-01

    The purpose of this qualitative study was to explore the meaning of the phrase "image of the nurse" in the context of the desired brand experience of assurance. A brand is a promise that lives in the minds of consumers. Nurses play a key role in delivering on the brand promise of a hospital. Using focus groups, the authors applied a deductive approach to generate data. Discussion transcripts were analyzed by establishing codes and identifying themes. The most frequent comment from participants was that for nurses to communicate assurance, they must 1st be clean, well groomed, and understated in overall appearance. Nurse behaviors that reassure patients include being present with patients, helping patients know what to expect, and demonstrating a consistent team approach. Overall appearance and behaviors define the image of nurses and contribute significantly to the brand of assurance.

  10. Ethics, Deafness, and New Medical Technologies

    ERIC Educational Resources Information Center

    Hintermair, Manfred; Albertini, John A.

    2005-01-01

    In the last 50 years, several new technologies have become enormously important within the Deaf community and have helped significantly to improve deaf people's lives in a hearing world. Current public attention and admiration, however, seems unduly focused on medical technologies that promise to solve "the problem" of being deaf. One reason for…

  11. The Efficacy of Psychophysiological Measures for Implementing Adaptive Technology

    NASA Technical Reports Server (NTRS)

    Scerbo, Mark W.; Freeman, Frederick G.; Mikulka, Peter J.; Parasuraman, Raja; DiNocero, Francesco; Prinzel, Lawrence J., III

    2001-01-01

    Adaptive automation refers to technology that can change its mode of operation dynamically. Further, both the technology and the operator can initiate changes in the level or mode of automation. The present paper reviews research on adaptive technology. It is divided into three primary sections. In the first section, issues surrounding the development and implementation of adaptive automation are presented. Because physiological-based measures show much promise for implementing adaptive automation, the second section is devoted to examining candidate indices. In the final section, those techniques that show the greatest promise for adaptive automation as well as issues that still need to be resolved are discussed.

  12. Accident tolerant fuel cladding development: Promise, status, and challenges

    NASA Astrophysics Data System (ADS)

    Terrani, Kurt A.

    2018-04-01

    The motivation for transitioning away from zirconium-based fuel cladding in light water reactors to significantly more oxidation-resistant materials, thereby enhancing safety margins during severe accidents, is laid out. A review of the development status for three accident tolerant fuel cladding technologies, namely coated zirconium-based cladding, ferritic alumina-forming alloy cladding, and silicon carbide fiber-reinforced silicon carbide matrix composite cladding, is offered. Technical challenges and data gaps for each of these cladding technologies are highlighted. Full development towards commercial deployment of these technologies is identified as a high priority for the nuclear industry.

  13. Autofluorescence imaging can identify preinvasive or clinically occult lesions in fallopian tube epithelium: a promising step towards screening and early detection.

    PubMed

    McAlpine, J N; El Hallani, S; Lam, S F; Kalloger, S E; Luk, M; Huntsman, D G; MacAulay, C; Gilks, C B; Miller, D M; Lane, P M

    2011-03-01

    cohort (73%; 83%; 57%; 91%) and in a subgroup that excluded non-serous histology (87.5%; 92%; 78%; 96%). Abnormal FT lesions can be identified using ex vivo optical imaging technologies. With this platform, we will move towards genomic interrogation of identified lesions, and developing in vivo screening modalities via falloposcopy. Copyright © 2010 Elsevier Inc. All rights reserved.

  14. Imaginaries of nuclear energy in the Portuguese parliament: Between promise, risk, and democracy.

    PubMed

    Santos Pereira, Tiago; Carvalho, António; Fonseca, Paulo F C

    2017-04-01

    This article explores the evolution of the nuclear energy debate and its associated controversies in the Portuguese parliament. The analysis focuses on the dictatorial regime of the New State (from the beginning of the nuclear program in 1951 until the 1974 revolution) and on the democratic period (post-1974). Portugal, as an exporting country of uranium minerals, significantly invested in the development of a national capacity in nuclear research, but never developed an endogenous nuclear power infrastructure. Through the analysis of parliamentary debates, this article characterizes the dynamic evolution of the Portuguese sociotechnical imaginary on nuclear energy and technology interlinked with ambivalent representations, including the promise of nuclear energy as key for the constitution of a technological Nation or as prompting new sociotechnical risks.

  15. A Multiplexed High-Content Screening Approach Using the Chromobody Technology to Identify Cell Cycle Modulators in Living Cells.

    PubMed

    Schorpp, Kenji; Rothenaigner, Ina; Maier, Julia; Traenkle, Bjoern; Rothbauer, Ulrich; Hadian, Kamyar

    2016-10-01

    Many screening hits show relatively poor quality regarding later efficacy and safety. Therefore, small-molecule screening efforts shift toward high-content analysis providing more detailed information. Here, we describe a novel screening approach to identify cell cycle modulators with low toxicity by combining the Cell Cycle Chromobody (CCC) technology with the CytoTox-Glo (CTG) cytotoxicity assay. The CCC technology employs intracellularly functional single-domain antibodies coupled to a fluorescent protein (chromobodies) to visualize the cell cycle-dependent redistribution of the proliferating cell nuclear antigen (PCNA) in living cells. This image-based cell cycle analysis was combined with determination of dead-cell protease activity in cell culture supernatants by the CTG assay. We adopted this multiplex approach to high-throughput format and screened 960 Food and Drug Administration (FDA)-approved drugs. By this, we identified nontoxic compounds, which modulate different cell cycle stages, and validated selected hits in diverse cell lines stably expressing CCC. Additionally, we independently validated these hits by flow cytometry as the current state-of-the-art format for cell cycle analysis. This study demonstrates that CCC imaging is a versatile high-content screening approach to identify cell cycle modulators, which can be multiplexed with cytotoxicity assays for early elimination of toxic compounds during screening. © 2016 Society for Laboratory Automation and Screening.

  16. National variety trials identify clones with high potential

    USDA-ARS?s Scientific Manuscript database

    Quality potato varieties are the backbone of a strong potato industry. Variety trials have been used to identify promising new varieties for well over a century. Trials are repeated and information collected over many years in order to confidently identify lines that may be well suited for productio...

  17. CXCL9, a promising biomarker in the diagnosis of chronic Q fever.

    PubMed

    Jansen, Anne F M; Schoffelen, Teske; Textoris, Julien; Mege, Jean-Louis; Nabuurs-Franssen, Marrigje; Raijmakers, Ruud P H; Netea, Mihai G; Joosten, Leo A B; Bleeker-Rovers, Chantal P; van Deuren, Marcel

    2017-08-09

    In the aftermath of the largest Q fever outbreak in the world, diagnosing the potentially lethal complication chronic Q fever remains challenging. PCR, Coxiella burnetii IgG phase I antibodies, CRP and 18 F-FDG-PET/CT scan are used for diagnosis and monitoring in clinical practice. We aimed to identify and test biomarkers in order to improve discriminative power of the diagnostic tests and monitoring of chronic Q fever. We performed a transcriptome analysis on C. burnetii stimulated PBMCs of 4 healthy controls and 6 chronic Q fever patients and identified genes that were most differentially expressed. The gene products were determined using Luminex technology in whole blood samples stimulated with heat-killed C. burnetii and serum samples from chronic Q fever patients and control subjects. Gene expression of the chemokines CXCL9, CXCL10, CXCL11 and CCL8 was strongly up-regulated in C. burnetii stimulated PBMCs of chronic Q fever patients, in contrast to healthy controls. In whole blood cultures of chronic Q fever patients, production of all four chemokines was increased upon C. burnetii stimulation, but also healthy controls and past Q fever individuals showed increased production of CXCL9, CXCL10 and CCL8. However, CXCL9 and CXCL11 production was significantly higher for chronic Q fever patients compared to past Q fever individuals. In addition, CXCL9 serum concentrations in chronic Q fever patients were higher than in past Q fever individuals. CXCL9 protein, measured in serum or as C. burnetii stimulated production, is a promising biomarker for the diagnosis of chronic Q fever.

  18. Imagining value, imagining users: academic technology transfer for health innovation.

    PubMed

    Miller, Fiona Alice; Sanders, Carrie B; Lehoux, Pascale

    2009-04-01

    Governments have invested heavily in the clinical and economic promise of health innovation and express increasing concern with the efficacy and efficiency of the health innovation system. In considering strategies for 'better' health innovation, policy makers and researchers have taken a particular interest in the work of universities and related public research organizations: How do these organizations identify and transfer promising innovations to market, and do these efforts make best use of public sector investments? We conducted an ethnographic study of technology transfer offices (TTOs) in Ontario and British Columbia, Canada, to consider the place of health and health system imperatives in judgments of value in early-stage health innovation. Our analysis suggests that the valuation process is poorly specified as a set of task-specific judgments. Instead, we argue that technology transfer professionals are active participants in the construction of the innovation and assign value by 'imagining' the end product in its 'context of use'. Oriented as they are to the commercialization of health technology, TTOs understand users primarily as market players. The immediate users of TTOs' efforts are commercial partners (i.e., licensees, investors) who are capable of translating current discoveries into future commodities. The ultimate end users - patients, clinicians, health systems - are the future consumers of the products to be sold. Attention to these proximate and more distal users in the valuation process is a complex and constitutive feature of the work of health technology transfer. At the same time, judgements about individual technologies are made in relation to a broader imperative through which TTOs seek to imagine and construct sustainable innovation systems. Judgments of value are rendered sensible in relation to the logic of valuation for systems of innovation that, in turn, configure users of health innovation in systemic ways.

  19. Benevolent technotopias and hitherto unimaginable meats: Tracing the promises of in vitro meat.

    PubMed

    Jönsson, Erik

    2016-10-01

    Today, in vitro (Latin: in glass) meat researchers strive to overhaul meat production technologies by producing meat outside animal bodies, primarily by culturing cells. In the process, meat should become healthier, more environmentally friendly and kinder to animals. In this article, I scrutinize (and problematize) this promissory discourse by examining the world that proponents envision alongside the world from which promises emerge. First, I trace the increasing number of publications striving to pinpoint the nature of in vitro meat to unveil the creation of an in vitro meat canon wherein perceived possibilities become taken for granted. Second, I investigate how the promissory discourse is often relatively silent on key aspects of how this technology could remake the world. Wet laboratories, animals and end products become foregrounded at the expense of political economy and the biophysical properties of cultured cells. Thus, questions concerning how funding requirements shape representations of this new technology, together with in vitro meat's particular socio-spatial and socio-ecological implications, become problematically de-emphasized.

  20. Nutrigenomics and the stewardship of scientific promises.

    PubMed

    Penders, Bart; Goven, Joanna

    2010-09-01

    Here we analyze the rise and establishment of nutrigenomics versus nutrition science from a political perspective. We argue that the exceptionalist status of nutrigenomics has been brought about by a carefully orchestrated economy of expectation, enabling the nutrigenomics community to develop its own research agenda that differs significantly from that of nutrition science. Nutrigenomics promotes research specifically directed towards the heterogeneity of dietary guidelines, while nutrition science pursues a public health goal dominated by homogeneous health messages. Through the development of genomic technology and the protective niche created by large global funding initiatives, this heterogeneity-research agenda has been able to develop itself. Those pursuing and supporting it have, through nutrigenomics' economy of expectation, influenced public opinion, and regulatory and political structures dealing with food and health. With many big global nutrigenomics initiatives slowly approaching their end, this article hints at some of the possible political consequences of its economy of expectation and suggests that a "stewardship" of promises and expectations is in order

  1. The application of digital image plane holography technology to identify Chinese herbal medicine

    NASA Astrophysics Data System (ADS)

    Wang, Huaying; Guo, Zhongjia; Liao, Wei; Zhang, Zhihui

    2012-03-01

    In this paper, the imaging technology of digital image plane holography to identify the Chinese herbal medicine is studied. The optical experiment system of digital image plane holography which is the special case of pre-magnification digital holography was built. In the record system, one is an object light by using plane waves which illuminates the object, and the other one is recording hologram by using spherical light wave as reference light. There is a Micro objective lens behind the object. The second phase factor which caus ed by the Micro objective lens can be eliminated by choosing the proper position of the reference point source when digital image plane holography is recorded by spherical light. In this experiment, we use the Lygodium cells and Onion cells as the object. The experiment results with Lygodium cells and Onion cells show that digital image plane holography avoid the process of finding recording distance by using auto-focusing approach, and the phase information of the object can be reconstructed more accurately. The digital image plane holography is applied to the microscopic imaging of cells more effectively, and it is suit to apply for the identify of Chinese Herbal Medicine. And it promotes the application of digital holographic in practice.

  2. Policy implications of technologies for cognitive enhancement

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sarewitz, Daniel R.; Karas, Thomas H.

    2007-02-01

    The Advanced Concepts Group at Sandia National Laboratory and the Consortium for Science, Policy and Outcomes at Arizona State University convened a workshop in May 2006 to explore the potential policy implications of technologies that might enhance human cognitive abilities. The group's deliberations sought to identify core values and concerns raised by the prospect of cognitive enhancement. The workshop focused on the policy implications of various prospective cognitive enhancements and on the technologies/nanotechnology, biotechnology, information technology, and cognitive science--that enable them. The prospect of rapidly emerging technological capabilities to enhance human cognition makes urgent a daunting array of questions, tensions,more » ambitions, and concerns. The workshop elicited dilemmas and concerns in ten overlapping areas: science and democracy; equity and justice; freedom and control; intergenerational issues; ethics and competition; individual and community rights; speed and deliberations; ethical uncertainty; humanness; and sociocultural risk. We identified four different perspectives to encompass the diverse issues related to emergence of cognitive enhancement technologies: (1) Laissez-faire--emphasizes freedom of individuals to seek and employ enhancement technologies based on their own judgment; (2) Managed technological optimism--believes that while these technologies promise great benefits, such benefits cannot emerge without an active government role; (3) Managed technological skepticism--views that the quality of life arises more out of society's institutions than its technologies; and (4) Human Essentialism--starts with the notion of a human essence (whether God-given or evolutionary in origin) that should not be modified. While the perspectives differ significantly about both human nature and the role of government, each encompasses a belief in the value of transparency and reliable information that can allow public discussion and

  3. New insights into old methods for identifying causal rare variants.

    PubMed

    Wang, Haitian; Huang, Chien-Hsun; Lo, Shaw-Hwa; Zheng, Tian; Hu, Inchi

    2011-11-29

    The advance of high-throughput next-generation sequencing technology makes possible the analysis of rare variants. However, the investigation of rare variants in unrelated-individuals data sets faces the challenge of low power, and most methods circumvent the difficulty by using various collapsing procedures based on genes, pathways, or gene clusters. We suggest a new way to identify causal rare variants using the F-statistic and sliced inverse regression. The procedure is tested on the data set provided by the Genetic Analysis Workshop 17 (GAW17). After preliminary data reduction, we ranked markers according to their F-statistic values. Top-ranked markers were then subjected to sliced inverse regression, and those with higher absolute coefficients in the most significant sliced inverse regression direction were selected. The procedure yields good false discovery rates for the GAW17 data and thus is a promising method for future study on rare variants.

  4. New and Emerging Technologies in Treatment of Lower Urinary Tract Symptoms From Benign Prostatic Hyperplasia.

    PubMed

    Gupta, Nikhil K; Gange, Steven N; McVary, Kevin T

    2018-03-29

    Lower urinary tract symptoms (LUTS) from bladder outlet obstruction from benign prostatic hyperplasia (BPH) occur in a large percentage of urologic patients. Treatment of this condition with medical and surgical therapy provides symptom relief but has serious adverse effects and causes sexual dysfunction. New technologies to treat BPH-associated LUTS aim to effectively treat urinary symptoms and minimize side effects and sexual dysfunction. To review the efficacy of new and emerging therapies for treatment of LUTS from BPH. A literature search was performed to identify therapies for LUTS from BPH with early outcomes data within the past 5 years. Improvement in International Prostate Symptom Score (IPSS) and effect on sexual functions such as erectile and ejaculatory functions as measured on the International Index of Erectile Function and the Male Sexual Health Questionnaire. Technologies introduced within the past 5 years include techniques using intraprostatic injectables, mechanical devices, and prostatic tissue ablation. Most technologies remain in the development phase and have only phase I and II studies available that show promising alleviation of urinary symptoms. Injectables have not typically surpassed placebo or sham effects, although special cohorts could be exceptions. Thus far, convective water vapor ablation therapy and prostatic urethral lift have shown the most promise, with short- and medium-term data available on phase III studies demonstrating significant improvement in IPSS with minimal impact on sexual function. Many of these technologies are limited in their potential treatment population by prostate size and conformation, whereas other therapies might be more generalizable. Many new technologies aim to treat LUTS from BPH and minimize sexual side effects. Most therapies remain experimental, although prostatic urethral lift and water vapor ablation therapy have been brought to market and show promise. Long-term durability of symptom relief

  5. Acquisition Modernization: Transitioning Technology Into Warfighter Capability

    DTIC Science & Technology

    2011-08-01

    to test and evaluate the technology and integrate the new capability into operational weapon systems (Figure 4). This funding model creates stove...misalignment between missions, TRLs, and the RDT&E funding model is a major 11 contributor to the valley of death. Technologies become obsolete on... funding model of the acquisition system. Create an individual budget account to fund the development of promising technologies. The Acquisition

  6. New and emerging technologies for genetic toxicity testing.

    PubMed

    Lynch, Anthony M; Sasaki, Jennifer C; Elespuru, Rosalie; Jacobson-Kram, David; Thybaud, Véronique; De Boeck, Marlies; Aardema, Marilyn J; Aubrecht, Jiri; Benz, R Daniel; Dertinger, Stephen D; Douglas, George R; White, Paul A; Escobar, Patricia A; Fornace, Albert; Honma, Masamitsu; Naven, Russell T; Rusling, James F; Schiestl, Robert H; Walmsley, Richard M; Yamamura, Eiji; van Benthem, Jan; Kim, James H

    2011-04-01

    The International Life Sciences Institute (ILSI) Health and Environmental Sciences Institute (HESI) Project Committee on the Relevance and Follow-up of Positive Results in In Vitro Genetic Toxicity (IVGT) Testing established an Emerging Technologies and New Strategies Workgroup to review the current State of the Art in genetic toxicology testing. The aim of the workgroup was to identify promising technologies that will improve genotoxicity testing and assessment of in vivo hazard and risk, and that have the potential to help meet the objectives of the IVGT. As part of this initiative, HESI convened a workshop in Washington, DC in May 2008 to discuss mature, maturing, and emerging technologies in genetic toxicology. This article collates the abstracts of the New and Emerging Technologies Workshop together with some additional technologies subsequently considered by the workgroup. Each abstract (available in the online version of the article) includes a section addressed specifically to the strengths, weaknesses, opportunities, and threats associated with the respective technology. Importantly, an overview of the technologies and an indication of how their use might be aligned with the objectives of IVGT are presented. In particular, consideration was given with regard to follow-up testing of positive results in the standard IVGT tests (i.e., Salmonella Ames test, chromosome aberration assay, and mouse lymphoma assay) to add weight of evidence and/or provide mechanism of action for improved genetic toxicity risk assessments in humans. Copyright © 2010 Wiley-Liss, Inc.

  7. Autism spectrum disorders in the era of mobile technologies: impact on caregivers.

    PubMed

    Allen, Anna A; Shane, Howard C

    2014-04-01

    This paper explores possible connections among existing literature on parental stress, augmentative and alternative communication (AAC), and use of mobile technology for persons with autism spectrum disorder (ASD). A narrative review of the literature. Parental support contributes to positive outcomes for children who use AAC. Parents identify communication as a high priority, but describe the process as challenging. AAC is often used with children with ASD, a population in which parental stress is especially high. Though there is research evidence that mobile technology is a promising tool for individuals with ASD, potentially misleading media anecdotes exist, and the effects on parental expectations and stress remain unstudied questions. Increased understanding of the connections in these research areas should help clarify the potential impact of mobile technologies on parental stress level, help to define appropriate future research directions, and contribute to development of appropriate caregiver training.

  8. GSA's Green Proving Ground: Identifying, Testing and Evaluating Innovative Technologies; Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kandt, A.; Lowell, M.

    2012-05-01

    This paper will provide an overview of the GPG program and its objectives as well as a summary and status update of the 16 technologies selected for enhanced testing and evaluation in 2011. The federal government's General Services Administration's (GSA) Public Buildings Service (PBS) acquires space on behalf of the federal government through new construction and leasing, and acts as a caretaker for federal properties across the country. PBS owns or leases 9,624 assets and maintains an inventory of more than 370.2 million square feet of workspace, and as such has enormous potential for implementing energy efficient and renewable energymore » technologies to reduce energy and water use and associated emissions. The Green Proving Ground (GPG) program utilizes GSA's real estate portfolio to test and evaluate innovative and underutilized sustainable building technologies and practices. Findings are used to support the development of GSA performance specifications and inform decision making within GSA, other federal agencies, and the real estate industry. The program aims to drive innovation in environmental performance in federal buildings and help lead market transformation through deployment of new technologies. In 2011, the GPG program selected 16 technologies or practices for rigorous testing and evaluation. Evaluations are currently being performed in collaboration with the Department of Energy's National Laboratories, and a steady stream of results will be forthcoming throughout 2012. This paper will provide an overview of the GPG program and its objectives as well as a summary and status update of the 16 technologies selected for enhanced testing and evaluation in 2011. Lastly, it provides a general overview of the 2012 program.« less

  9. Something's Coming, Something Good: Identifying TPACK Competence in Pre-Service Teachers' Analyses of Learning Objects

    ERIC Educational Resources Information Center

    Lloyd, Margaret

    2013-01-01

    There is a song at the beginning of the musical, West Side Story, where the character Tony sings that "something's coming, something good." The song is an anthem of optimism, brimming with promise. This paper is about the long-held promise of information and communication technology (ICT) to transform teaching and learning, to modernise…

  10. A Bright Promise but a Dim Future. Researchers Examine Potential of Educational Technology.

    ERIC Educational Resources Information Center

    Pitts, Marcella R., Ed.

    Concerns about the current educational technology movement are discussed in these four papers which were presented during a seminar of 20 representatives from 10 Council for Educational Development and Research (CEDaR) member institutions. The first by Marcella Pitts and E. Joseph Schneider provides an overview of the educational technology…

  11. Privacy and the New Technology

    ERIC Educational Resources Information Center

    Godwin, William F.; Bode, Katharine Anne

    1971-01-01

    Technology has been charged with destroying personal privacy. Protection by control of human incentives holds most promise. This article suggests several steps we can take to avoid any individual gain from acquiring information about others. (Author)

  12. Encouraging Innovation for Assistive Health Technologies in Dementia: Barriers, Enablers and Next Steps to Be Taken.

    PubMed

    Egan, Kieren J; Pot, Anne Margriet

    2016-04-01

    Innovative Assistive Health Technology (AHT) has the potential to improve the quality of life for people with dementia or their families. Although development is in its preliminary stages, research shows first promising results. Despite such progress, we are still to observe widespread integration of technology into communities. If society is to benefit from innovative AHT to assist people with dementia and their caregivers, we must deepen our understanding of the needs, barriers, and enablers of innovative AHT. In March 2015, multinational focus groups were undertaken to identify the barriers, enablers, stakeholder actions, and a future perspective for the use of AHT in dementia. This exploratory study was carried out in preparation of the first World Health Organization Ministerial Conference on the Global Action against Dementia. The focus group study identified that innovative AHT for people with dementia and caregivers is at an early stage of development; however, there is substantial promise across a range of different care needs. Focus group discussions identified internationally relevant barriers and enablers for the development of innovative AHT centring on an improved understanding for needs in dementia. There are many diverse barriers to the development of innovative AHT but none that appear insurmountable regarding the enablers that were mentioned. There is now an overriding imperative for a systematic, coordinated multistakeholder approach with the needs of people with dementia and their caregivers as the centerpiece. Copyright © 2016. Published by Elsevier Inc.

  13. Artificial intelligence technology assessment for the US Army Depot System Command

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pennock, K A

    1991-07-01

    This assessment of artificial intelligence (AI) has been prepared for the US Army's Depot System Command (DESCOM) by Pacific Northwest Laboratory. The report describes several of the more promising AI technologies, focusing primarily on knowledge-based systems because they have been more successful in commercial applications than any other AI technique. The report also identifies potential Depot applications in the areas of procedural support, scheduling and planning, automated inspection, training, diagnostics, and robotic systems. One of the principal objectives of the report is to help decisionmakers within DESCOM to evaluate AI as a possible tool for solving individual depot problems. Themore » report identifies a number of factors that should be considered in such evaluations. 22 refs.« less

  14. Case Study of Manor New Tech High School: Promising Practices in STEM Education for Comprehensive High Schools

    ERIC Educational Resources Information Center

    Gourgey, Hannah; Asiabanpour, Bahram; Fenimore, Carol

    2010-01-01

    The following paper culminates a year of research conducted by researchers at E[superscript 3] Alliance and Texas State University and sponsored by the National Science Foundation. The following reports on promising practices observed and reported at Manor New Tech High School (MNTH), a Texas Science Technology Engineering Mathematics (T-STEM)…

  15. The Promise of New Ideas and New Technology for Improving Teaching and Learning

    ERIC Educational Resources Information Center

    Novak, Joseph D.

    2003-01-01

    There have been enormous advances in our understanding of human learning in the past three decades. There have also been important advances in our understanding of the nature of knowledge and new knowledge creation. These advances, when combined with the explosive development of the Internet and other technologies, permit advances in educational…

  16. Case studies on forecasting for innovative technologies: frequent revisions improve accuracy.

    PubMed

    Lerner, Jeffrey C; Robertson, Diane C; Goldstein, Sara M

    2015-02-01

    Health technology forecasting is designed to provide reliable predictions about costs, utilization, diffusion, and other market realities before the technologies enter routine clinical use. In this article we address three questions central to forecasting's usefulness: Are early forecasts sufficiently accurate to help providers acquire the most promising technology and payers to set effective coverage policies? What variables contribute to inaccurate forecasts? How can forecasters manage the variables to improve accuracy? We analyzed forecasts published between 2007 and 2010 by the ECRI Institute on four technologies: single-room proton beam radiation therapy for various cancers; digital breast tomosynthesis imaging technology for breast cancer screening; transcatheter aortic valve replacement for serious heart valve disease; and minimally invasive robot-assisted surgery for various cancers. We then examined revised ECRI forecasts published in 2013 (digital breast tomosynthesis) and 2014 (the other three topics) to identify inaccuracies in the earlier forecasts and explore why they occurred. We found that five of twenty early predictions were inaccurate when compared with the updated forecasts. The inaccuracies pertained to two technologies that had more time-sensitive variables to consider. The case studies suggest that frequent revision of forecasts could improve accuracy, especially for complex technologies whose eventual use is governed by multiple interactive factors. Project HOPE—The People-to-People Health Foundation, Inc.

  17. Identifying Teacher Belief Systems Regarding Classroom Technology Use--Planning for Perceptions

    ERIC Educational Resources Information Center

    Petty, Michael F.

    2012-01-01

    Across the United States, millions of taxpayer dollars are spent on the integration of technology into America's classrooms to increase student achievement and preparation for a 21st century global workforce. The problem is teachers are not using available technology to its fullest capacity. While several studies outlined in the literature review…

  18. Contexts for Promise: Noteworthy Practices and Innovations in the Identification of Gifted Students.

    ERIC Educational Resources Information Center

    Callahan, Carolyn M., Ed.; And Others

    This monograph contains 11 papers describing model projects that address the identification of gifted students. An introduction by Carolyn M. Callahan and Carol A. Tomlinson identifies commonalities and themes in the promising practices highlighted in the papers. The papers include: (1) "Project STREAM: Support, Training and Resources for…

  19. Barriers and benefits to using mobile health technology after operation: A qualitative study.

    PubMed

    Abelson, Jonathan S; Kaufman, Elinore; Symer, Matthew; Peters, Alexander; Charlson, Mary; Yeo, Heather

    2017-09-01

    Recently, mobile health technology has emerged as a promising avenue for improving physician-patient communication and patient outcomes. The objective of our study was to determine the public's perception of barriers and benefits to using mobile health technology technologies to enhance recovery after operation. We used the Empire State Poll to ask 2 open-ended questions to 800 participants assessing their perceptions of benefits and barriers to use mobile health technology after operation. All responses were coded independently, and any discrepancies were resolved by consensus. We used grounded theory to allow themes to arise from the codes. Interrater reliability was calculated using Cohen's Kappa. Participants identified a range of possible barriers to using mobile health technology apps after operation including: protecting personal health information, technology effectiveness and failure, preference for face-to-face interaction with their surgeon, level of effort required, and ability of the older adults to navigate mobile health technology. Participants identified multiple possible benefits including: better monitoring, improved communication with their surgeon, minimizing follow-up visits, improved convenience, and increased patient knowledge. In the study, 15% of all respondents stated there were no barriers whereas 6% stated there were no benefits. Participants were receptive to the many potential benefits of this technology to enhance not only their relationships with providers and the convenience of access, but also their health outcomes. We must address participants concerns about data security and their fears of losing a personal relationship with their doctor. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Bioencapsulation technologies in tissue engineering

    PubMed Central

    Majewski, Rebecca L.; Zhang, Wujie; Ma, Xiaojun; Cui, Zhanfeng; Ren, Weiping; Markel, David C.

    2017-01-01

    Bioencapsulation technologies have played an important role in the developing successes of tissue engineering. Besides offering immunoisolation, they also show promise for cell/tissue banking and the directed differentiation of stem cells, by providing a unique microenvironment. This review describes bioencapsulation technologies and summarizes their recent progress in research into tissue engineering. The review concludes with a brief outlook regarding future research directions in this field. PMID:27716872

  1. Identifying Critical Manufacturing Technologies Required for Transforming the Army Industrial Base

    DTIC Science & Technology

    2014-04-01

    mechanism, 1 = least common mechanism)? ................................................................... 29 Figure 5 – Which Technology “ Test Beds...facilities, produce new designs , and incorporate efficient manufacturing processes. The value and continued success of the Army Industrial Base depends on...in materiel supplies to troops. Specific programs, described in AR 700-09, that are designed to transition manufacturing technology into the Army

  2. Technology Base Research Project for electrochemical energy storage

    NASA Astrophysics Data System (ADS)

    Kinoshita, K.

    1985-06-01

    The DOE Electrochemical Energy Storage Program is divided into two projects: (1) the exploratory technology development and testing (ETD) project and (2) the technology base research (TBR) project. The role of the TBR Project is to perform supporting research for the advanced battery systems under development by the ETD Project, and to evaluate new systems with potentially superior performance, durability and/or cost characteristics. The specific goal of the TBR Project is to identify the most promising electrochemical technologies and transfer them to industry and/or the ETD Project for further development and scale-up. This report summarizes the research, financial, and management activities relevant to the TBR Project in CY 1984. General problem areas addressed by the project include identification of new electrochemical couples for advanced batteries, determination of technical feasibility of the new couples, improvements in battery components and materials, establishment of engineering principles applicable to electrochemical energy storage and conversion, and the assessment of fuel-cell technology for transportation applications. Major emphasis is given to applied research which will lead to superior performance and lower life-cycle costs. The TBR Project is divided into three major project elements: exploratory research, applied science research, and air systems research.

  3. Technology base research project for electrochemical energy storage

    NASA Astrophysics Data System (ADS)

    Kinoshita, Kim

    1988-07-01

    The progress made by the technology base research (TBR) project for electrochemical energy storage during calendar year 1987 was summarized. The primary objective of the TBR Project, which is sponsored by the Department of Energy (DOE) and managed by Lawrence Berkeley Laboratory (LBL), is to identify electrochemical technologies that can satisfy stringent performance and economic requirements for electric vehicles and stationary energy storage applications. The ultimate goal is to transfer the most promising electrochemical technologies to the private sector or to another DOE project (e.g., Sandia National Laboratories' Exploratory Technology Development and Testing Project) for further development and scale-up. Besides LBL, which has overall responsibility for the TBR Project, Los Alamos National Laboratory (LANL), Brookhaven National Laboratory (BNL) and Argonne National Laboratory (ANL) participate in the TBR Project by providing key research support in several of the project elements. The TBR Project consists of three major project elements: exploratory research; applied science research; and air systems research. The objectives and the specific battery and electrochemical systems addressed by each project element are discussed in the following sections, which also include technical summaries that relate to the individual projects. Financial information that relates to the various projects and a description of the management activities for the TBR Project are described in the Executive Summary.

  4. Evolution of technology convergence networks in Korea: Characteristics of temporal changes in R&D according to institution type.

    PubMed

    Choi, Jae Young; Jeong, Seongkyoon; Jung, Jung-Kyu

    2018-01-01

    This study investigates the temporal changes in development of technology convergence networks by institution type, i.e., public research institute (PRI), university and industry. Using the co-classification of technological domains of patents, we identified technology convergence of Korean patents, which were filed at Korea Intellectual Properties Office (KIPO) from 1997 to 2011. We conducted a network analysis at the technology level to search for the key technology fields and frequent instances of technology convergence. The results show that technology convergence networks have grown significantly in the recent period regardless of the institution type. While industries started to conspicuously engage in technology convergence in the late 1990s, universities or PRIs did not do so until the mid-2000s. This discrepancy in the phase of technology convergence is attributed to the temporal difference in R&D stage (e.g., basic research and commercial product development). Our findings imply that corporal and governmental R&D management decision on promising technology fields will be more effective if the decision makers carefully consider the type of R&D entity in analyzing technological landscapes.

  5. Evolution of technology convergence networks in Korea: Characteristics of temporal changes in R&D according to institution type

    PubMed Central

    Choi, Jae Young; Jeong, Seongkyoon

    2018-01-01

    This study investigates the temporal changes in development of technology convergence networks by institution type, i.e., public research institute (PRI), university and industry. Using the co-classification of technological domains of patents, we identified technology convergence of Korean patents, which were filed at Korea Intellectual Properties Office (KIPO) from 1997 to 2011. We conducted a network analysis at the technology level to search for the key technology fields and frequent instances of technology convergence. The results show that technology convergence networks have grown significantly in the recent period regardless of the institution type. While industries started to conspicuously engage in technology convergence in the late 1990s, universities or PRIs did not do so until the mid-2000s. This discrepancy in the phase of technology convergence is attributed to the temporal difference in R&D stage (e.g., basic research and commercial product development). Our findings imply that corporal and governmental R&D management decision on promising technology fields will be more effective if the decision makers carefully consider the type of R&D entity in analyzing technological landscapes. PMID:29420574

  6. Sonographic Examination of The Fetus Vis-à-Vis Shoulder Dystocia: A Vexing Promise.

    PubMed

    Doty, Morgen S; Al-Hafez, Leen; Chauhan, Suneet P

    2016-12-01

    Since antepartum and intrapartum risk factors are poor at identifying women whose labor is complicated by shoulder dystocia, sonographic examination of the fetus holds promise. Though there are several measurements of biometric parameters to identify the parturient who will have shoulder dystocia, none are currently clinically useful. Three national guidelines confirm that sonographic measurements do not serve as appropriate diagnostic tests to identify women who will have shoulder dystocia with or without concurrent injury. In summary, biometric measurements of the fetus should not be used to alter clinical management with the aim of averting shoulder dystocia.

  7. A promising new thermoelectric material - Ruthenium silicide

    NASA Technical Reports Server (NTRS)

    Vining, Cronin B.; Mccormack, Joseph A.; Zoltan, Andrew; Zoltan, Leslie D.

    1991-01-01

    Experimental and theoretical efforts directed toward increasing thermoelectric figure of merit values by a factor of 2 or 3 have been encouraging in several respects. An accurate and detailed theoretical model developed for n-type silicon-germanium (SiGe) indicates that ZT values several times higher than currently available are expected under certain conditions. These new, high ZT materials are expected to be significantly different from SiGe, but not unreasonably so. Several promising candidate materials have been identified which may meet the conditions required by theory. One such candidate, ruthenium silicide, currently under development at JPL, has been estimated to have the potential to exhibit figure of merit values 4 times higher than conventional SiGe materials. Recent results are summarized.

  8. Current-day precision oncology: from cancer prevention, screening, drug development, and treatment - have we fallen short of the promise?

    PubMed

    Morgan, Gilberto; Aftimos, Philippe; Awada, Ahmad

    2016-09-01

    Precision oncology has been a strategy of prevention, screening, and treatment. Although much has been invested, have the results fallen so far short of the promise? The advancement of technology and research has opened new doors, yet a variety of pitfalls are present. This review presents the successes, failures, and opportunities of precision oncology in the current landscape. The use of targeted gene sequencing and the overwhelming results of superresponders have generated much excitement and support for precision oncology from the medical community. Despite notable successes, many challenges still pave the way of precision oncology: intratumoral heterogeneity, the need for serial biopsies, availability of treatments, target prioritization, ethical issues with germline incidental findings, medical education, clinical trial design, and costs. Precision oncology shows much potential through the use of next-generation sequencing and molecular advances, but does this potential warrant the investment? There are many obstacles on the way of this technology that should make us question if the investment (both monetary and man-hours) will live up to the promise. The review aims to not criticize this technology, but to give a realistic view of where we are, especially regarding cancer treatment and prevention.

  9. Information Technologies in Florida's Rural Hospitals: Does System Affiliation Matter?

    ERIC Educational Resources Information Center

    Menachemi, Nir; Burke, Darrell; Clawson, Art; Brooks, Robert G.

    2005-01-01

    Context: The recent explosive growth of information technology in hospitals promises to improve hospital and patient outcomes. Financial barriers may cause rural hospitals to lag in adoption of information technology, however, formal studies that examine rural hospital adoption of information technology are lacking. Purpose: To determine the…

  10. Aligning Digital Video Technology with Game Pedagogy in Physical Education

    ERIC Educational Resources Information Center

    Koekoek, Jeroen; van der Mars, Hans; van der Kamp, John; Walinga, Wytse; van Hilvoorde, Ivo

    2018-01-01

    The rapid development of digital technology has expanded the prospects and promises for its application in physical education programs. Physical educators are becoming increasingly interested in technology but often remain inadequately equipped to effectively integrate these technological resources in their daily practice, and/or lack the…

  11. Making Something of It: The Untold Stories of Promising Black Males at a Predominately White Institution of Higher Education

    ERIC Educational Resources Information Center

    Funk, Michael Sean

    2012-01-01

    Promising Black males are an understudied and underserved population in the field of higher education. The purpose of this study was to understand how promising Black males define academic success and to identify the factors that affect academic success at a large predominately White public institutions of higher education located in the…

  12. Latino Immigrants, Acculturation, and Health: Promising New Directions in Research.

    PubMed

    Abraído-Lanza, Ana F; Echeverría, Sandra E; Flórez, Karen R

    2016-01-01

    This article provides an analysis of novel topics emerging in recent years in research on Latino immigrants, acculturation, and health. In the past ten years, the number of studies assessing new ways to conceptualize and understand how acculturation-related processes may influence health has grown. These new frameworks draw from integrative approaches testing new ground to acknowledge the fundamental role of context and policy. We classify the emerging body of evidence according to themes that we identify as promising directions--intrapersonal, interpersonal, social environmental, community, political, and global contexts, cross-cutting themes in life course and developmental approaches, and segmented assimilation--and discuss the challenges and opportunities each theme presents. This body of work, which considers acculturation in context, points to the emergence of a new wave of research that holds great promise in driving forward the study of Latino immigrants, acculturation, and health. We provide suggestions to further advance the ideologic and methodologic rigor of this new wave.

  13. FMCSA’s advanced system testing utilizing a data acquisition system on the highways (FAST DASH) safety technology evaluation project #3 : novel convex mirrors : technology brief.

    DOT National Transportation Integrated Search

    2016-11-01

    The Federal Motor Carrier Safety Administration (FMCSA) established the FAST DASH program to perform efficient independent evaluations of promising safety technologies aimed at commercial vehicle operations. In this third FAST DASH safety technology ...

  14. Review of optical memory technologies

    NASA Technical Reports Server (NTRS)

    Chen, D.

    1972-01-01

    Optical technologies for meeting the demands of large capacity fast access time memory are discussed in terms of optical phenomena and laser applications. The magneto-optic and electro-optic approaches are considered to be the most promising memory approaches.

  15. Using TV white space spectrum to practise telemedicine: A promising technology to enhance broadband internet connectivity within healthcare facilities in rural regions of developing countries.

    PubMed

    Chavez, Afton; Littman-Quinn, Ryan; Ndlovu, Kagiso; Kovarik, Carrie L

    2016-06-01

    The following correspondence provides an overview of TV White Space (TVWS) technology, regulations, and potential applications to the health care sector. This report also introduces "Project Kgolagano," a Botswana-based initiative representing the first endeavour to utilize TVWS internet connection for practising telemedicine. TV "white space" refers to the previously unused, wasted spectrum within TV radiofrequency channels that can now be leveraged to obtain broadband internet access. TVWS represents a less costly, faster, and farther-reaching internet connection that is a promising option for connecting the previously unconnected populations of remote and underserved areas. The Botswana-University of Pennsylvania Partnership, Microsoft, Botswana Innovation Hub, Vista Life Sciences, and Global Broadband Solutions have partnered together to bring TVWS wireless broadband access to healthcare facilities in poorly connected regions of Botswana (Lobatse, Francistown, Maun, Gaborone) in order to improve healthcare delivery and facilitate telemedicine in dermatology, cervical cancer screening, and family medicine (HIV/AIDS, TB, general adult and pediatric medicine). © The Author(s) 2015.

  16. Technological characterization and probiotic traits of yeasts isolated from Altamura sourdough to select promising microorganisms as functional starter cultures for cereal-based products.

    PubMed

    Perricone, Marianne; Bevilacqua, Antonio; Corbo, Maria Rosaria; Sinigaglia, Milena

    2014-04-01

    The main topic of this research was to select some suitable functional starter cultures for cereal-based food or beverages. This aim was achieved through a step-by step approach focused on the technological characterization, as well as on the evaluation of the probiotic traits of yeasts; the technological characterization relied on the assessment of enzymatic activities (catalase, urease, β-glucosidase), growth under various conditions (pH, temperature, addition of salt, lactic and acetic acids) and leavening ability. The results of this step were used as input data for a Principal Component Analysis; thus, the most technologically relevant 18 isolates underwent a second selection for their probiotic traits (survival at pH 2.5 and with bile salts added, antibiotic resistance, antimicrobial activity towards foodborne pathogens, hydrophobic properties and biofilm production) and were identified through genotyping. Two isolates (Saccharomyces cerevisiae strain 2 and S. cerevisiae strain 4) were selected and analyzed in the last step for the simulation of the gastric transit; these isolates showed a trend similar to S. cerevisiae var. boulardii ATCC MYA-796, a commercial probiotic yeast used as control. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. How might contact with nature promote human health? Promising mechanisms and a possible central pathway.

    PubMed

    Kuo, Ming

    2015-01-01

    How might contact with nature promote human health? Myriad studies have linked the two; at this time the task of identifying the mechanisms underlying this link is paramount. This article offers: (1) a compilation of plausible pathways between nature and health; (2) criteria for identifying a possible central pathway; and (3) one promising candidate for a central pathway. The 21 pathways identified here include environmental factors, physiological and psychological states, and behaviors or conditions, each of which has been empirically tied to nature and has implications for specific physical and mental health outcomes. While each is likely to contribute to nature's impacts on health to some degree and under some circumstances, this paper explores the possibility of a central pathway by proposing criteria for identifying such a pathway and illustrating their use. A particular pathway is more likely to be central if it can account for the size of nature's impacts on health, account for nature's specific health outcomes, and subsume other pathways. By these criteria, enhanced immune functioning emerges as one promising candidate for a central pathway between nature and health. There may be others.

  18. Fundamental Technology Development for Gas-Turbine Engine Health Management

    NASA Technical Reports Server (NTRS)

    Mercer, Carolyn R.; Simon, Donald L.; Hunter, Gary W.; Arnold, Steven M.; Reveley, Mary S.; Anderson, Lynn M.

    2007-01-01

    Integrated vehicle health management technologies promise to dramatically improve the safety of commercial aircraft by reducing system and component failures as causal and contributing factors in aircraft accidents. To realize this promise, fundamental technology development is needed to produce reliable health management components. These components include diagnostic and prognostic algorithms, physics-based and data-driven lifing and failure models, sensors, and a sensor infrastructure including wireless communications, power scavenging, and electronics. In addition, system assessment methods are needed to effectively prioritize development efforts. Development work is needed throughout the vehicle, but particular challenges are presented by the hot, rotating environment of the propulsion system. This presentation describes current work in the field of health management technologies for propulsion systems for commercial aviation.

  19. A New Scheme to Characterize and Identify Protein Ubiquitination Sites.

    PubMed

    Nguyen, Van-Nui; Huang, Kai-Yao; Huang, Chien-Hsun; Lai, K Robert; Lee, Tzong-Yi

    2017-01-01

    Protein ubiquitination, involving the conjugation of ubiquitin on lysine residue, serves as an important modulator of many cellular functions in eukaryotes. Recent advancements in proteomic technology have stimulated increasing interest in identifying ubiquitination sites. However, most computational tools for predicting ubiquitination sites are focused on small-scale data. With an increasing number of experimentally verified ubiquitination sites, we were motivated to design a predictive model for identifying lysine ubiquitination sites for large-scale proteome dataset. This work assessed not only single features, such as amino acid composition (AAC), amino acid pair composition (AAPC) and evolutionary information, but also the effectiveness of incorporating two or more features into a hybrid approach to model construction. The support vector machine (SVM) was applied to generate the prediction models for ubiquitination site identification. Evaluation by five-fold cross-validation showed that the SVM models learned from the combination of hybrid features delivered a better prediction performance. Additionally, a motif discovery tool, MDDLogo, was adopted to characterize the potential substrate motifs of ubiquitination sites. The SVM models integrating the MDDLogo-identified substrate motifs could yield an average accuracy of 68.70 percent. Furthermore, the independent testing result showed that the MDDLogo-clustered SVM models could provide a promising accuracy (78.50 percent) and perform better than other prediction tools. Two cases have demonstrated the effective prediction of ubiquitination sites with corresponding substrate motifs.

  20. Promising behavior change techniques in a multicomponent intervention to reduce concerns about falls in old age: a Delphi study.

    PubMed

    Vestjens, Lotte; Kempen, Gertrudis I J M; Crutzen, Rik; Kok, Gerjo; Zijlstra, G A Rixt

    2015-04-01

    Complex behavior change interventions need evidence regarding the effectiveness of individual components to understand how these interventions work. The objective of this study was to identify the least and most promising behavior change techniques (BCTs) within the Dutch intervention 'A Matter of Balance' (AMB-NL) aimed at concerns about falls in old age as an example. After the identification of 27 BCTs within AMB-NL, an online two-round Delphi survey among 16 international experts was conducted to reach consensus on the least and most promising BCTs. The level of consensus and the level of importance of BCTs were determined. In total, 23 of the 27 (>85%) BCTs identified reached consensus. Most promising BCTs were goal setting (behavior), graded tasks and behavioral practice/rehearsal. Information about health consequences, salience of consequences and information about emotional consequences were considered least promising. These outcomes provide a first but important step in the evidence building process regarding the effectiveness of BCTs in a complex intervention. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  1. Functionalised particles using dry powder coating in pharmaceutical drug delivery: promises and challenges.

    PubMed

    Dahmash, Eman Z; Mohammed, Afzal R

    2015-01-01

    Production of functionalised particles using dry powder coating is a one-step, environmentally friendly process that paves the way for the development of particles with targeted properties and diverse functionalities. Applying the first principles in physical science for powders, fine guest particles can be homogeneously dispersed over the surface of larger host particles to develop functionalised particles. Multiple functionalities can be modified including: flowability, dispersibility, fluidisation, homogeneity, content uniformity and dissolution profile. The current publication seeks to understand the fundamental underpinning principles and science governing dry coating process, evaluate key technologies developed to produce functionalised particles along with outlining their advantages, limitations and applications and discusses in detail the resultant functionalities and their applications. Dry particle coating is a promising solvent-free manufacturing technology to produce particles with targeted functionalities. Progress within this area requires the development of continuous processing devices that can overcome challenges encountered with current technologies such as heat generation and particle attrition. Growth within this field requires extensive research to further understand the impact of process design and material properties on resultant functionalities.

  2. Perspectives on micropole undulators in synchrotron radiation technology

    NASA Astrophysics Data System (ADS)

    Tatchyn, Roman; Csonka, Paul; Toor, Arthur

    1989-07-01

    Micropole undulators promise to advance synchrotron radiation (SR) technology in two distinct ways. The first is in the development of economical, low-energy storage rings, or linacs, as soft x-ray sources, and the second is in the opening up of gamma-ray spectral ranges on high-energy storage rings. In this paper the promise and current status of micropole undulator (MPU) technology are discussed, and a review of some practical obstacles to the implementation of MPU's on present-day storage rings is given. Some successful results of recent performance measurements of micropole undulators on the Lawrence Livermore National Laboratory linac are briefly summarized.

  3. GSA's Green Proving Ground: Identifying, Testing and Evaluating Innovative Technologies (Presentation)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kandt, A.; Lowell, M.

    2012-05-01

    GSA's Green Proving Ground (GPG) program utilizes GSA's real estate portfolio to test and evaluate innovative and underutilized sustainable building technologies and practices. Findings are used to support the development of GSA performance specifications and inform decision making within GSA, other federal agencies, and the real estate industry. The program aims to drive innovation in environmental performance in federal buildings and help lead market transformation through deployment of new technologies.

  4. Electronic aroma detection technology for forensic and law enforcement applications

    NASA Astrophysics Data System (ADS)

    Barshick, Stacy-Ann; Griest, Wayne H.; Vass, Arpad A.

    1997-02-01

    A major problem hindering criminal investigations is the lack of appropriate tools for proper crime scene investigations. Often locating important pieces of evidence means relying on the ability of trained detection canines. Development of analytical technology to uncover and analyze evidence, potentially at the scene, could serve to expedite criminal investigations, searches, and court proceedings. To address this problem, a new technology based on gas sensor arrays was investigated for its applicability to forensic and law enforcement problems. The technology employs an array of sensors that respond to volatile chemical components yielding a characteristic 'fingerprint' pattern representative of the vapor-phase composition of a sample. Sample aromas can be analyzed and identified using artificial neural networks that are trained on known aroma patterns. Several candidate applications based on known technological needs of the forensic and law enforcement communities have been investigated. These applications have included the detection of aromas emanating from cadavers to aid in determining time since death, drug detection for deterring the manufacture, sale, and use of drugs of abuse, and the analysis of fire debris for accelerant identification. The result to date for these applications have been extremely promising and demonstrate the potential applicability of this technology for forensic use.

  5. The quest to apply VR technology to rehabilitation: tribulations and treasures.

    PubMed

    Keshner, Emily A; Fung, Joyce

    2017-01-01

    The papers that follow stem from a symposium presented at the International Society for Posture and Gait Research (ISPGR) in Seville, Spain, in July 2015. Four speakers were charged with presenting their methods of applying virtual reality (VR) technology to obtain meaningful rehabilitation outcomes. The symposium aims to explore characteristics of VR that modify mechanisms supporting motor relearning. Common impairments in posture and gait that can be modulated within virtual environments by employing motor learning concepts, including sensory augmentation and repetition, were examined. Critical overviews of VR applications that address different therapeutic objectives for improving posture and gait in individuals with neurological insult or injury were presented. A further goal was to identify approaches and efforts to bridge the gap between knowledge generation from research and knowledge uptake in clinical practice. Specific objectives of this symposium were that participants be able to: 1) identify benefits and limitations of selecting VR as an intervention tool; 2) discuss how VR relates to principles for motor relearning following neurological insult or injury; and 3) identify areas and methods for future translation of VR technology in clinical and home-based settings. Our symposium concluded that the application of VR technology in assessment, treatment, and research has yielded promising results in transferring learned cognitive and motor skills to more natural environments. VR permits the user to interact with a multidimensional and multisensory environment in real time, and offers the opportunity to provide both standardized and individualized interventions while monitoring behavior.

  6. Social Relations and Technology: Continuity, Context, and Change

    PubMed Central

    Antonucci, Toni C; Ajrouch, Kristine J; Manalel, Jasmine A

    2017-01-01

    Abstract Social relations, although basic to human nature, health and well-being, have become increasingly complicated as a result of changing population demography and technology. In this essay, we provide a historical overview of social relations, especially as they affect older people. We briefly review the evolution of theory and measurement surrounding social relations as well as early empirical evidence. We consider how social relations have changed over time as well as continuity and change regarding basic characteristics of social relations. Of special interest is the emerging influence of technology on how people maintain contact, especially the changing ways people can use technology to increase, decrease, maintain, or avoid social relations. We consider both negative and positive aspects of these new technologies and their influence on health and well-being. Finally, we conclude that new and emerging technologies hold great promise for the future by overcoming traditional barriers to maintaining social contact, support exchange, and information acquisition. Nevertheless, we caution that these new technologies can have the dehumanizing effect of distance thus creating the potential for insensitivity and increased negativity. In sum, we are cautiously optimistic about the promise of technology to expand, but not replace, traditional forms of social contact. PMID:29795794

  7. Social Relations and Technology: Continuity, Context, and Change.

    PubMed

    Antonucci, Toni C; Ajrouch, Kristine J; Manalel, Jasmine A

    2017-11-01

    Social relations, although basic to human nature, health and well-being, have become increasingly complicated as a result of changing population demography and technology. In this essay, we provide a historical overview of social relations, especially as they affect older people. We briefly review the evolution of theory and measurement surrounding social relations as well as early empirical evidence. We consider how social relations have changed over time as well as continuity and change regarding basic characteristics of social relations. Of special interest is the emerging influence of technology on how people maintain contact, especially the changing ways people can use technology to increase, decrease, maintain, or avoid social relations. We consider both negative and positive aspects of these new technologies and their influence on health and well-being. Finally, we conclude that new and emerging technologies hold great promise for the future by overcoming traditional barriers to maintaining social contact, support exchange, and information acquisition. Nevertheless, we caution that these new technologies can have the dehumanizing effect of distance thus creating the potential for insensitivity and increased negativity. In sum, we are cautiously optimistic about the promise of technology to expand, but not replace, traditional forms of social contact.

  8. Personalized Exposure Assessment: Promising Approaches for Human Environmental Health Research

    PubMed Central

    Weis, Brenda K.; Balshaw, David; Barr, John R.; Brown, David; Ellisman, Mark; Lioy, Paul; Omenn, Gilbert; Potter, John D.; Smith, Martyn T.; Sohn, Lydia; Suk, William A.; Sumner, Susan; Swenberg, James; Walt, David R.; Watkins, Simon; Thompson, Claudia; Wilson, Samuel H.

    2005-01-01

    New technologies and methods for assessing human exposure to chemicals, dietary and lifestyle factors, infectious agents, and other stressors provide an opportunity to extend the range of human health investigations and advance our understanding of the relationship between environmental exposure and disease. An ad hoc Committee on Environmental Exposure Technology Development was convened to identify new technologies and methods for deriving personalized exposure measurements for application to environmental health studies. The committee identified a “toolbox” of methods for measuring external (environmental) and internal (biologic) exposure and assessing human behaviors that influence the likelihood of exposure to environmental agents. The methods use environmental sensors, geographic information systems, biologic sensors, toxicogenomics, and body burden (biologic) measurements. We discuss each of the methods in relation to current use in human health research; specific gaps in the development, validation, and application of the methods are highlighted. We also present a conceptual framework for moving these technologies into use and acceptance by the scientific community. The framework focuses on understanding complex human diseases using an integrated approach to exposure assessment to define particular exposure–disease relationships and the interaction of genetic and environmental factors in disease occurrence. Improved methods for exposure assessment will result in better means of monitoring and targeting intervention and prevention programs. PMID:16002370

  9. Teen Culture, Technology and Literacy Instruction: Urban Adolescent Students' Perspectives

    ERIC Educational Resources Information Center

    Li, Jia; Snow, Catherine; White, Claire

    2015-01-01

    Modern teens have pervasively integrated new technologies into their lives, and technology has become an important component of teen popular culture. Educators have pointed out the promise of exploiting technology to enhance students' language and literacy skills and general academic success. However, there is no consensus on the effect of…

  10. Technology push, market pull, and the Valley of Death

    NASA Astrophysics Data System (ADS)

    Swift, Gregory W.

    2005-09-01

    The Valley of Death is the gap between fundamental research and product development, where apparently promising technologies can stall or disappear. Fundamental researchers may hope for potential applications of their work, and they try to push technology based on their research. Businesses may hope that new technology might serve their market needs, and they try to find promising new technologies that can be pulled toward practical use. The valley between the researchers and the businesses can be surprisingly twisted and thorny, despite government attempts to build roads across it. The histories of cryogenic engineering in the late 20th century and of thermoacoustics work at Los Alamos offer examples of both useful and misguided strategies in this valley. Although global thermoacoustics R&D has not (yet?) been as successful as cryogenic engineering, thermoacoustics has thus far avoided some of the worst pitfalls in the valley.

  11. Technology Games: Using Wittgenstein for Understanding and Evaluating Technology.

    PubMed

    Coeckelbergh, Mark

    2017-08-15

    In the philosophy of technology after the empirical turn, little attention has been paid to language and its relation to technology. In this programmatic and explorative paper, it is proposed to use the later Wittgenstein, not only to pay more attention to language use in philosophy of technology, but also to rethink technology itself-at least technology in its aspect of tool, technology-in-use. This is done by outlining a working account of Wittgenstein's view of language (as articulated mainly in the Investigations) and by then applying that account to technology-turning around Wittgenstein's metaphor of the toolbox. Using Wittgenstein's concepts of language games and form of life and coining the term 'technology games', the paper proposes and argues for a use-oriented, holistic, transcendental, social, and historical approach to technology which is empirically but also normatively sensitive, and which takes into account implicit knowledge and know-how. It gives examples of interaction with social robots to support the relevance of this project for understanding and evaluating today's technologies, makes comparisons with authors in philosophy of technology such as Winner and Ihde, and sketches the contours of a phenomenology and hermeneutics of technology use that may help us to understand but also to gain a more critical relation to specific uses of concrete technologies in everyday contexts. Ultimately, given the holism argued for, it also promises a more critical relation to the games and forms of life technologies are embedded in-to the ways we do things.

  12. The Concept of Resource Use Efficiency as a Theoretical Basis for Promising Coal Mining Technologies

    NASA Astrophysics Data System (ADS)

    Mikhalchenko, Vadim

    2017-11-01

    The article is devoted to solving one of the most relevant problems of the coal mining industry - its high resource use efficiency, which results in high environmental and economic costs of operating enterprises. It is shown that it is the high resource use efficiency of traditional, historically developed coal production systems that generates a conflict between indicators of economic efficiency and indicators of resistance to uncertainty and variability of market environment parameters. The traditional technological paradigm of exploitation of coal deposits also predetermines high, technology-driven, economic risks. The solution is shown and a real example of the problem solution is considered.

  13. Objectivity in Grading: The Promise of Bar Codes

    ERIC Educational Resources Information Center

    Jae, Haeran; Cowling, John

    2009-01-01

    This article proposes the use of a new technology to assure student anonymity and reduce bias hazards: identifying students by using bar codes. The limited finding suggests that the use of bar codes for assuring student anonymity could potentially cause students to perceive that grades are assigned more fairly and reassure teachers that they are…

  14. Modelling Benefits-Oriented Costs for Technology Enhanced Learning

    ERIC Educational Resources Information Center

    Laurillard, Diana

    2007-01-01

    The introduction of technology enhanced learning (TEL) methods changes the deployment of the most important resource in the education system: teachers' and learners' time. New technology promises greater personalization and greater productivity, but without careful modeling of the effects on the use of staff time, TEL methods can easily increase…

  15. Technology: Education and Training Needs of Older Adults

    ERIC Educational Resources Information Center

    Huber, Lesa; Watson, Carol

    2014-01-01

    The impact of the global aging of the population on social, economic, political, and health care institutions is unequaled. Parallel to this, evolving developments in technology promise opportunities for sales and product development to support positive aging. Older adults are excited to utilize technologies that they perceive as practical.…

  16. Transforming Global Health with Mobile Technologies and Social Enterprises

    PubMed Central

    Kayingo, Gerald

    2012-01-01

    More than 2,000 people convened for the ninth annual Global Health and Innovation Conference at Yale University on April 21-22, 2012. Participants discussed the latest innovations, ideas in development, lessons learned, opportunities and challenges in global health activities. Several themes emerged, including the important role of frontline workers, strengthening health systems, leveraging social media, and sustainable and impact-driven philanthropy. Overall, the major outcome of the conference was the increased awareness of the potential of mobile technologies and social enterprises in transforming global health. Experts warned that donations and technological advances alone will not transform global health unless there are strong functioning health infrastructures and improved workforce. It was noted that there is a critical need for an integrated systems approach to global health problems and a need for scaling up promising pilot projects. Lack of funding, accountability, and sustainability were identified as major challenges in global health. PMID:23012591

  17. Magnetocaloric Materials Revolutionize Refrigeration Technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Momen, Ayyoub

    Researchers at Oak Ridge National Laboratory have partnered with General Electric (GE) Appliances on a building technologies project to revolutionize today’s 100-year-old home refrigeration technology. Using magnetocaloric materials (MCM), they’ve eliminated the need for a vapor compression cycle, associated refrigerants, and their negative environmental impacts. The research team is currently working to determine the most effective means to transfer heat from the solid MCM, and using fluid passed through high-resolution microchannels shows promise. This technology has the potential to reduce energy consumption by 25%, and GE hopes to commercialize magnetocaloric refrigerators for use in homes by 2020.

  18. Space technologies for short-term earthquake warning

    NASA Astrophysics Data System (ADS)

    Pulinets, S.

    Recent theoretical and experimental studies explicitly demonstrated the ability of space technologies to identify and monitor the specific variations at near-earth space plasma, atmosphere and ground surface associated with approaching severe earthquakes (named as earthquake precursors) appearing several days (from 1 to 5) before the seismic shock over the seismically active areas. Several countries and private companies are in the stage of preparation (or already launched) the dedicated spacecrafts for monitoring of the earthquake precursors from space and for short-term earthquake prediction. The present paper intends to outline the optimal algorithm for creation of the space-borne system for the earthquake precursors monitoring and for short-term earthquake prediction. It takes into account the following considerations: Selection of the precursors in the terms of priority, taking into account their statistical and physical parameters Configuration of the spacecraft payload Configuration of the satellite constellation (orbit selection, satellite distribution, operation schedule) Proposal of different options (cheap microsatellite or comprehensive multisatellite constellation) Taking into account that the most promising are the ionospheric precursors of earthquakes, the special attention will be devoted to the radiophysical techniques of the ionosphere monitoring. The advantages and disadvantages of such technologies as vertical sounding, in-situ probes, ionosphere tomography, GPS TEC and GPS MET technologies will be considered.

  19. Space technologies for short-term earthquake warning

    NASA Astrophysics Data System (ADS)

    Pulinets, S. A.

    Recent theoretical and experimental studies explicitly demonstrated the ability of space technologies to identify and monitor the specific variations at near-earth space plasma, atmosphere and ground surface associated with approaching severe earthquakes (named as earthquake precursors) which appear several days (from 1 to 5) before the seismic shock over the seismically active areas. Several countries and private companies are in the stage of preparation (or already launched) the dedicated spacecrafts for monitoring of the earthquake precursors from space and for short-term earthquake prediction. The present paper intends to outline the optimal algorithm for creation of the space-borne system for the earthquake precursors monitoring and for short-term earthquake prediction. It takes into account the following: Selection of the precursors in the terms of priority, considering their statistical and physical parameters.Configuration of the spacecraft payload.Configuration of the satellite constellation (orbit selection, satellite distribution, operation schedule).Different options of the satellite systems (cheap microsatellite or comprehensive multisatellite constellation). Taking into account that the most promising are the ionospheric precursors of earthquakes, the special attention is devoted to the radiophysical techniques of the ionosphere monitoring. The advantages and disadvantages of such technologies as vertical sounding, in-situ probes, ionosphere tomography, GPS TEC and GPS MET technologies are considered.

  20. The social control of energy: A case for the promise of decentralized solar technologies

    NASA Astrophysics Data System (ADS)

    Gilmer, R. W.

    1980-05-01

    Decentralized solar technology and centralized electric utilities were contrasted in the ways they assign property rights in capital and energy output; in the assignment of operational control; and in the means of monitoring, policing, and enforcing property rights. An analogy was drawn between the decision of an energy consumer to use decentralized solar and the decision of a firm to vertically integrate, that is, to extend the boundary of a the firm to vertically integrate, that is, to extend the boundary of the firm by making inputs or further processing output. Decentralized solar energy production offers the small energy consumer the chance to cut ties to outside suppliers--to vertically integrate energy production into the home or business. The development of this analogy provides insight into important noneconomic aspects of solar energy, and it points clearly to the lighter burdens of social management offered by decentralized solar technology.

  1. Technology Candidates for Air-to-Air and Air-to-Ground Data Exchange

    NASA Technical Reports Server (NTRS)

    Haynes, Brian D.

    2015-01-01

    Technology Candidates for Air-to-Air and Air-to-Ground Data Exchange is a two-year research effort to visualize the U. S. aviation industry at a point 50 years in the future, and to define potential communication solutions to meet those future data exchange needs. The research team, led by XCELAR, was tasked with identifying future National Airspace System (NAS) scenarios, determining requirements and functions (including gaps), investigating technical and business issues for air, ground, & air-to-ground interactions, and reporting on the results. The project was conducted under technical direction from NASA and in collaboration with XCELAR's partner, National Institute of Aerospace, and NASA technical representatives. Parallel efforts were initiated to define the information exchange functional needs of the future NAS, and specific communication link technologies to potentially serve those needs. Those efforts converged with the mapping of each identified future NAS function to potential enabling communication solutions; those solutions were then compared with, and ranked relative to, each other on a technical basis in a structured analysis process. The technical solutions emerging from that process were then assessed from a business case perspective to determine their viability from a real-world adoption and deployment standpoint. The results of that analysis produced a proposed set of future solutions and most promising candidate technologies. Gap analyses were conducted at two points in the process, the first examining technical factors, and the second as part of the business case analysis. In each case, no gaps or unmet needs were identified in applying the solutions evaluated to the requirements identified. The future communication solutions identified in the research comprise both specific link technologies and two enabling technologies that apply to most or all specific links. As a result, the research resulted in a new analysis approach, viewing the

  2. Research and Technology

    NASA Technical Reports Server (NTRS)

    1982-01-01

    This report is prepared on an annual basis for the purposes of highlighting the fiscal year research and technology (R&T) activities. Its intent !s to better inform the R&T Program Managers of significant accomplishments that promise practical and beneficial program application. The report is not inclusive of all R&T activities. This document will be updated in November of each year.

  3. 76 FR 55889 - Reopening Notice: Promise Neighborhoods Program-Implementation Grant Competition; Promise...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-09

    ... AGENCY: Office of Innovation and Improvement, Department of Education. ACTION: Notice. SUMMARY: The Department of Education (Department) reopens the competition for transmittal of applications for new awards... DEPARTMENT OF EDUCATION [CFDA Numbers 84.215N; 84.215P] Reopening Notice: Promise Neighborhoods...

  4. Reduced cost alternatives to premise wiring using ATM and microcellular technologies

    NASA Technical Reports Server (NTRS)

    Gejji, Raghvendra R.

    1993-01-01

    The cost of premises wiring keeps increasing due to personnel moves, new equipment, capacity upgrades etc. It would be desirable to have a wireless interface from the workstations to the fixed network, so as to minimize the wiring changes needed. New technologies such as microcellular personal communication systems are promising to bring down the cost of wireless communication. Another promising technology is Code Division Multiple Access (CDMA), which could dramatically increase the bandwidth available for wireless connections. In addition, Asynchronous Transfer Mode (ATM) technology is emerging as a technique for integrated management of voice, data, and video traffic on a single network. The focus of this investigation will be to assess the future utility of these new technologies for reducing the premise wiring cost at KSC. One of the issues to be studied is the cost comparison of 'old' versus 'new,' especially as time and technology progress. An additional issue for closer study is a feasible time-line for progress in technological capability.

  5. The Internship Divide: The Promise and Challenges of Internships in the Arts. Special Report

    ERIC Educational Resources Information Center

    Frenette, Alexandre

    2015-01-01

    The Strategic National Alumni Project (SNAAP)--an online survey, data management, and institutional improvement system designed to enhance the impact of arts-school education--brings much-needed nuance to assessing the promise and addressing the challenges of the intern economy. In particular, SNAAP data help participants identify historical…

  6. Emerging desalination technologies for water treatment: a critical review.

    PubMed

    Subramani, Arun; Jacangelo, Joseph G

    2015-05-15

    In this paper, a review of emerging desalination technologies is presented. Several technologies for desalination of municipal and industrial wastewater have been proposed and evaluated, but only certain technologies have been commercialized or are close to commercialization. This review consists of membrane-based, thermal-based and alternative technologies. Membranes based on incorporation of nanoparticles, carbon nanotubes or graphene-based ones show promise as innovative desalination technologies with superior performance in terms of water permeability and salt rejection. However, only nanocomposite membranes have been commercialized while others are still under fundamental developmental stages. Among the thermal-based technologies, membrane distillation and adsorption desalination show the most promise for enhanced performance with the availability of a waste heat source. Several alternative technologies have also been developed recently; those based on capacitive deionization have shown considerable improvements in their salt removal capacity and feed water recovery. In the same category, microbial desalination cells have been shown to desalinate high salinity water without any external energy source, but to date, scale up of the process has not been methodically evaluated. In this paper, advantages and drawbacks of each technology is discussed along with a comparison of performance, water quality and energy consumption. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Phage display as a promising approach for vaccine development.

    PubMed

    Aghebati-Maleki, Leili; Bakhshinejad, Babak; Baradaran, Behzad; Motallebnezhad, Morteza; Aghebati-Maleki, Ali; Nickho, Hamid; Yousefi, Mehdi; Majidi, Jafar

    2016-09-29

    Bacteriophages are specific antagonists to bacterial hosts. These viral entities have attracted growing interest as optimal vaccine delivery vehicles. Phages are well-matched for vaccine design due to being highly stable under harsh environmental conditions, simple and inexpensive large scale production, and potent adjuvant capacities. Phage vaccines have efficient immunostimulatory effects and present a high safety profile because these viruses have made a constant relationship with the mammalian body during a long-standing evolutionary period. The birth of phage display technology has been a turning point in the development of phage-based vaccines. Phage display vaccines are made by expressing multiple copies of an antigen on the surface of immunogenic phage particles, thereby eliciting a powerful and effective immune response. Also, the ability to produce combinatorial peptide libraries with a highly diverse pool of randomized ligands has transformed phage display into a straightforward, versatile and high throughput screening methodology for the identification of potential vaccine candidates against different diseases in particular microbial infections. These libraries can be conveniently screened through an affinity selection-based strategy called biopanning against a wide variety of targets for the selection of mimotopes with high antigenicity and immunogenicity. Also, they can be panned against the antiserum of convalescent individuals to recognize novel peptidomimetics of pathogen-related epitopes. Phage display has represented enormous promise for finding new strategies of vaccine discovery and production and current breakthroughs promise a brilliant future for the development of different phage-based vaccine platforms.

  8. Smart Gun Technology project. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Weiss, D.R.

    The goal of the Smart Gun Technology project is to eliminate the capability of an unauthorized user form firing a law officer`s firearm by implementing user-recognizing-and-authorizing (or {open_quotes}smart{close_quotes}) surety technologies. This project was funded by the National Institute of Justice. This report lists the findings and results of the project`s three primary objectives. First, to find and document the requirements for a smart firearm technology that law enforcement officers will value. Second, to investigate, evaluate, and prioritize technologies that meet the requirements for a law enforcement officer`s smart firearm. Third, to demonstrate and document the most promising technology`s usefulness inmore » models of a smart firearm.« less

  9. Rigorous Screening Technology for Identifying Suitable CO2 Storage Sites II

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    George J. Koperna Jr.; Vello A. Kuuskraa; David E. Riestenberg

    2009-06-01

    This report serves as the final technical report and users manual for the 'Rigorous Screening Technology for Identifying Suitable CO2 Storage Sites II SBIR project. Advanced Resources International has developed a screening tool by which users can technically screen, assess the storage capacity and quantify the costs of CO2 storage in four types of CO2 storage reservoirs. These include CO2-enhanced oil recovery reservoirs, depleted oil and gas fields (non-enhanced oil recovery candidates), deep coal seems that are amenable to CO2-enhanced methane recovery, and saline reservoirs. The screening function assessed whether the reservoir could likely serve as a safe, long-term CO2more » storage reservoir. The storage capacity assessment uses rigorous reservoir simulation models to determine the timing, ultimate storage capacity, and potential for enhanced hydrocarbon recovery. Finally, the economic assessment function determines both the field-level and pipeline (transportation) costs for CO2 sequestration in a given reservoir. The screening tool has been peer reviewed at an Electrical Power Research Institute (EPRI) technical meeting in March 2009. A number of useful observations and recommendations emerged from the Workshop on the costs of CO2 transport and storage that could be readily incorporated into a commercial version of the Screening Tool in a Phase III SBIR.« less

  10. Robotics in rehabilitation: technology as destiny.

    PubMed

    Stein, Joel

    2012-11-01

    Robotic aids for rehabilitation hold considerable promise but have not yet achieved widespread clinical adoption. Barriers to adoption include the limited data on efficacy, the single-purpose design of existing robots, financial considerations, and clinician lack of familiarity with this technology. Although the path forward to clinical adoption may be slow and have several false starts, the labor-saving aspect of robotic technology will ultimately ensure its adoption.

  11. Promising Practices in Undergraduate Science, Technology, Engineering, and Mathematics Education: Summary of Two Workshops

    ERIC Educational Resources Information Center

    Nielsen, Natalie

    2011-01-01

    Numerous teaching, learning, assessment, and institutional innovations in undergraduate science, technology, engineering, and mathematics (STEM) education have emerged in the past decade. Because virtually all of these innovations have been developed independently of one another, their goals and purposes vary widely. Some focus on making science…

  12. The Technological Society: Implications for Women in the Workplace.

    ERIC Educational Resources Information Center

    Cianni, Mary; Weitz, Anna D.

    1986-01-01

    Although increased technology is altering the nature of work, familiar barriers continue to exist for women. Examines the equity of access to technology, the career implications for those employed at home, and the realities of newly promised occupational opportunities. Implications for counselors are discussed. (Author/BL)

  13. Perspectives on next-generation technology for environmental sensor networks

    Treesearch

    Barbara J. Benson; Barbara J. Bond; Michael P. Hamilton; Russell K. Monson; Richard Han

    2009-01-01

    Sensor networks promise to transform and expand environmental science. However, many technological difficulties must be overcome to achieve this potential. Partnerships of ecologists with computer scientists and engineers are critical in meeting these challenges. Technological issues include promoting innovation in new sensor design, incorporating power optimization...

  14. Heterojunction bipolar transistor technology for data acquisition and communication

    NASA Technical Reports Server (NTRS)

    Wang, C.; Chang, M.; Beccue, S.; Nubling, R.; Zampardi, P.; Sheng, N.; Pierson, R.

    1992-01-01

    Heterojunction Bipolar Transistor (HBT) technology has emerged as one of the most promising technologies for ultrahigh-speed integrated circuits. HBT circuits for digital and analog applications, data conversion, and power amplification have been realized, with speed performance well above 20 GHz. At Rockwell, a baseline AlGaAs/GaAs HBT technology has been established in a manufacturing facility. This paper describes the HBT technology, transistor characteristics, and HBT circuits for data acquisition and communication.

  15. Citizen Science in the Classroom: Perils and Promise of the New Web

    NASA Astrophysics Data System (ADS)

    Loughran, T.; Dirksen, R.

    2010-12-01

    Classroom citizen science projects invite students to generate, curate, post, query, and analyze data, publishing and discussing results in potentially large collaborative contexts. The new web offers a rich palette of such projects for any STEM educator to select from or create. This easy access to citizen science in the classroom is full of both promise and peril for science education. By offering examples of classroom citizen science projects in particle physics, earth and environmental sciences, each supported by a common mashup of technologies available to ordinary users, we will illustrate something of the promise of these projects for science education, and point to some of the challenges and failure modes--the peril--raised by easy access and particularly easy publication of data. How one sensibly responds to this promise and peril depends on how one views the goals of science (or more broadly, STEM) education: either as the equipping of individual students with STEM knowledge and skills so as to empower them for future options, or as the issuing of effective invitations into STEM communities. Building on the claim that these are complementary perspectives, both of value, we will provide an example of a classroom citizen science project analyzed from both perspectives. The BOSCO classroom-to-classroom water source mapping project provides students both in Northern Uganda and in South Dakota a collaborative platform for analyzing and responding to local water quality concerns. Students gather water quality data, use Google Forms embedded in a project wiki to enter data in a spreadsheet, which then automatically (through Mapalist, a free web service) gets posted to a Google Map, itself embedded in the project wiki. Using these technologies, data is thus collected and posted for analysis in a collaborative environment: the stage is set for classroom citizen science. In the context of this project we will address the question of how teachers can take advantage

  16. Promising Practices for Education Technology

    ERIC Educational Resources Information Center

    Zielezinski, Molly B.

    2017-01-01

    Despite all of the celebratory rhetoric around our nation's declining dropout rates, during a given year, nearly 20 percent of students expected to graduate do not. Furthermore, according to Johns Hopkins University and Civic Enterprises, "unacceptably low levels of minority, low-income, English Language Learners, and special education…

  17. Promising intervention strategies to reduce parents' use of physical punishment.

    PubMed

    Gershoff, Elizabeth T; Lee, Shawna J; Durrant, Joan E

    2017-09-01

    The strong and ever-growing evidence base demonstrating that physical punishment places children at risk for a range of negative outcomes, coupled with global recognition of children's inherent rights to protection and dignity, has led to the emergence of programs specifically designed to prevent physical punishment by parents. This paper describes promising programs and strategies designed for each of three levels of intervention - indicated, selective, and universal - and summarizes the existing evidence base of each. Areas for further program development and evaluation are identified. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Children's understanding of promising, lying, and false belief.

    PubMed

    Maas, Fay K

    2008-07-01

    Understanding promising and lying requires an understanding of intention and the ability to interpret mental states. The author examined (a) the extent to which 4- to 6-year-olds focus on the sincerity of the speaker's intention when the 4-to 6-year-olds make judgments about promises and lies and (b) whether false-belief reasoning skills are related to understanding promising and lying. Participants watched videotaped stories and made promise and lie judgments from their own perspective and from the listener-character's perspective. Children also completed false-belief reasoning tasks. Older children made more correct promise judgments from both perspectives. All children made correct lie judgments from the listener's perspective. The author found that Ist-order false-belief reasoning was related to making judgments from the participant's perspective; 2nd-order false-belief reasoning was related to making judgments from the listener-character's perspective. Results suggest that children's understanding of promising and lying moves from a focus on outcome toward a focus on the belief that each utterance is designed to create.

  19. Gravitational-wave astronomy: delivering on the promises

    NASA Astrophysics Data System (ADS)

    Schutz, B. F.

    2018-05-01

    Now that LIGO and Virgo have begun to detect gravitational-wave events with regularity, the field of gravitational-wave astronomy is beginning to realize its promise. Binary black holes and, very recently, binary neutron stars have been observed, and we are already learning much from them. The future, with improved sensitivity, more detectors and detectors like LISA in different frequency bands, has even more promise to open a completely hidden side of the Universe to our exploration. This article is part of a discussion meeting issue `The promises of gravitational-wave astronomy'.

  20. The Renewed Promise of Medical Informatics

    PubMed Central

    2016-01-01

    Summary The promise of the field of Medical Informatics has been great and its impact has been significant. In 1999, the Yearbook editors of the International Medical Informatics Association (IMIA) - also the authors of the present paper - sought to assess this impact by selecting a number of seminal papers in the field, and asking experts to comment on these articles. In particular, it was requested whether and how the expectations, represented by these papers, had been fulfilled since their publication several decades earlier. Each expert was also invited to comment on what might be expected in the future. In the present paper, these areas are briefly reviewed again. Where did these early papers have an impact and where were they not as successful as originally expected? It should be noted that the extraordinary developments in computer technology observed in the last two decades could not have been foreseen by these early researchers. In closing, some of the possibilities and limitations of research in medical informatics are outlined in the context of a framework that considers six levels of computer applications in medicine and health care. For each level, some predictions are made for the future, concluded with thoughts on fruitful areas for ongoing research in the field. PMID:27199195

  1. The Renewed Promise of Medical Informatics.

    PubMed

    van Bemmel, J H; McCray, A T

    2016-05-20

    The promise of the field of Medical Informatics has been great and its impact has been significant. In 1999, the Yearbook editors of the International Medical Informatics Association (IMIA) - also the authors of the present paper - sought to assess this impact by selecting a number of seminal papers in the field, and asking experts to comment on these articles. In particular, it was requested whether and how the expectations, represented by these papers, had been fulfilled since their publication several decades earlier. Each expert was also invited to comment on what might be expected in the future. In the present paper, these areas are briefly reviewed again. Where did these early papers have an impact and where were they not as successful as originally expected? It should be noted that the extraordinary developments in computer technology observed in the last two decades could not have been foreseen by these early researchers. In closing, some of the possibilities and limitations of research in medical informatics are outlined in the context of a framework that considers six levels of computer applications in medicine and health care. For each level, some predictions are made for the future, concluded with thoughts on fruitful areas for ongoing research in the field.

  2. Identifying Characteristics of Technology and Engineering Teachers Striving for Excellence Using a Modified Delphi

    ERIC Educational Resources Information Center

    Rose, Mary Annette; Shumway, Steven; Carter, Vinson; Brown, Josh

    2015-01-01

    Preparing a technology and engineering (TE) teacher who strives for teaching excellence is a fundamental mission of TE teacher education programs in the United States. In 2012, the International Technology and Engineering Educators Association (ITEEA, formerly the International Technology Education Association, ITEA) Council on Technology and…

  3. Payload software technology

    NASA Technical Reports Server (NTRS)

    1976-01-01

    A software analysis was performed of known STS sortie payload elements and their associated experiments. This provided basic data for STS payload software characteristics and sizes. A set of technology drivers was identified based on a survey of future technology needs and an assessment of current software technology. The results will be used to evolve a planned approach to software technology development. The purpose of this plan is to ensure that software technology is advanced at a pace and a depth sufficient to fulfill the identified future needs.

  4. Technology-assisted rehabilitation interventions following pediatric brain injury.

    PubMed

    Wade, Shari L; Narad, Megan E; Shultz, Emily L; Kurowski, Brad G; Miley, Aimee E; Aguilar, Jessica M; Adlam, Anna-Lynne R

    2018-04-01

    Following traumatic brain injury (TBI), children experience a variety of physical, motor, speech, and cognitive deficits that can have a long-term detrimental impact. The emergence and popularity of new technologies has led to research into the development of various apps, gaming systems, websites, and robotics that might be applied to rehabilitation. The objective of this narrative review was to describe the current literature regarding technologically-assisted interventions for the rehabilitation of motor, neurocognitive, behavioral, and family impairments following pediatric TBI. We conducted a series of searches for peer-reviewed manuscripts published between 2000 and 2017 that included a technology-assisted component in the domains of motor, language/communication, cognition, behavior, social competence/functioning, family, and academic/school-based functioning. Findings suggested several benefits of utilizing technology in TBI rehabilitation including facilitating engagement/adherence, increasing access to therapies, and improving generalizability across settings. There is fairly robust evidence regarding the efficacy of online family problem-solving therapy in improving behavior problems, executive functioning, and family functioning. There was less compelling, but still promising, evidence regarding the efficacy other technology for motor deficits, apps for social skills, and computerized programs for cognitive skills. Overall, many studies were limited in the rigor of their methodology due to small heterogeneous samples and lack of control groups. Technology-assisted interventions have the potential to enhance pediatric rehabilitation after TBI. Future research is needed to further support their efficacy with larger controlled trials and to identify characteristics of children who are most likely to benefit.

  5. Advanced component technologies for energy-efficient turbofan engines

    NASA Technical Reports Server (NTRS)

    Saunders, N. T.

    1980-01-01

    The paper reviews NASA's Energy Efficient Engine Project which was initiated to provide the advanced technology base for a new generation of fuel-conservative engines for introduction into airline service by the late 1980s. Efforts in this project are directed at advancing engine component and systems technologies to a point of demonstrating technology-readiness by 1984. Early results indicate high promise in achieving most of the goals established in the project.

  6. Review of early assessment models of innovative medical technologies.

    PubMed

    Fasterholdt, Iben; Krahn, Murray; Kidholm, Kristian; Yderstræde, Knud Bonnet; Pedersen, Kjeld Møller

    2017-08-01

    Hospitals increasingly make decisions regarding the early development of and investment in technologies, but a formal evaluation model for assisting hospitals early on in assessing the potential of innovative medical technologies is lacking. This article provides an overview of models for early assessment in different health organisations and discusses which models hold most promise for hospital decision makers. A scoping review of published studies between 1996 and 2015 was performed using nine databases. The following information was collected: decision context, decision problem, and a description of the early assessment model. 2362 articles were identified and 12 studies fulfilled the inclusion criteria. An additional 12 studies were identified and included in the review by searching reference lists. The majority of the 24 early assessment studies were variants of traditional cost-effectiveness analysis. Around one fourth of the studies presented an evaluation model with a broader focus than cost-effectiveness. Uncertainty was mostly handled by simple sensitivity or scenario analysis. This review shows that evaluation models using known methods assessing cost-effectiveness are most prevalent in early assessment, but seems ill-suited for early assessment in hospitals. Four models provided some usable elements for the development of a hospital-based model. Crown Copyright © 2017. Published by Elsevier B.V. All rights reserved.

  7. Making the Connection: Technological Literacy and Technology Assessment.

    ERIC Educational Resources Information Center

    Deal, Walter F.

    2002-01-01

    Technology assessment is the process of identifying, analyzing, and evaluating potential consequences of technology. Tools for assessing and forecasting impact include relevance trees and futures wheels. Activities based on these tools can be used to teach assessment to technology education students. (SK)

  8. Membrane-based processes for wastewater nutrient recovery: Technology, challenges, and future direction.

    PubMed

    Xie, Ming; Shon, Ho Kyong; Gray, Stephen R; Elimelech, Menachem

    2016-02-01

    Wastewater nutrient recovery holds promise for more sustainable water and agricultural industries. We critically review three emerging membrane processes - forward osmosis (FO), membrane distillation (MD) and electrodialysis (ED) - that can advance wastewater nutrient recovery. Challenges associated with wastewater nutrient recovery were identified. The advantages and challenges of applying FO, MD, and ED technologies to wastewater nutrient recovery are discussed, and directions for future research and development are identified. Emphasis is given to exploration of the unique mass transfer properties of these membrane processes in the context of wastewater nutrient recovery. We highlight that hybridising these membrane processes with existing nutrient precipitation process will lead to better management of and more diverse pathways for near complete nutrient recovery in wastewater treatment facilities. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. The Fourth Revolution; Instructional Technology in Higher Education.

    ERIC Educational Resources Information Center

    Carnegie Commission on Higher Education , Berkeley, CA.

    The technology of communications and data processing that has had a profound impact on American Society generally in recent decades promises to have powerful influences on higher education as well. What these influences may be and what steps should be taken to assure that the benefits of instructional technology will be realized in an orderly and…

  10. Magnetocaloric Materials Revolutionize Refrigeration Technology

    ScienceCinema

    Momen, Ayyoub

    2018-06-25

    Researchers at Oak Ridge National Laboratory have partnered with General Electric (GE) Appliances on a building technologies project to revolutionize today’s 100-year-old home refrigeration technology. Using magnetocaloric materials (MCM), they’ve eliminated the need for a vapor compression cycle, associated refrigerants, and their negative environmental impacts. The research team is currently working to determine the most effective means to transfer heat from the solid MCM, and using fluid passed through high-resolution microchannels shows promise. This technology has the potential to reduce energy consumption by 25%, and GE hopes to commercialize magnetocaloric refrigerators for use in homes by 2020.

  11. Information technology principles for management, reporting, and research.

    PubMed

    Gillam, Michael; Rothenhaus, Todd; Smith, Vernon; Kanhouwa, Meera

    2004-11-01

    Information technology holds the promise to enhance the ability of individuals and organizations to manage emergency departments, improve data sharing and reporting, and facilitate research. The Society for Academic Emergency Medicine (SAEM) Consensus Committee has identified nine principles to outline a path of optimal features and designs for current and future information technology systems. The principles roughly summarized include the following: utilize open database standards with clear data dictionaries, provide administrative access to necessary data, appoint and recognize individuals with emergency department informatics expertise, allow automated alert and proper identification for enrollment of cases into research, provide visual and statistical tools and training to analyze data, embed automated configurable alarm functionality for clinical and nonclinical systems, allow multiexport standard and format configurable reporting, strategically acquire mission-critical equipment that is networked and capable of automated feedback regarding functional status and location, and dedicate resources toward informatics research and development. The SAEM Consensus Committee concludes that the diligent application of these principles will enhance emergency department management, reporting, and research and ultimately improve the quality of delivered health care.

  12. False Images but a New Promise in Universities' Contribution to Industrial and Technological Advance.

    ERIC Educational Resources Information Center

    Shattock, M. L.

    1987-01-01

    The major contributions of university science in the two World Wars, the funding declines in inter- and post-war periods, and government and industry policies are cited as evidence that the educational system alone has not been responsible for technological decline. They are contrasted with U.S. policies and practices in university research. (MSE)

  13. Flight deck automation: Promises and realities

    NASA Technical Reports Server (NTRS)

    Norman, Susan D. (Editor); Orlady, Harry W. (Editor)

    1989-01-01

    Issues of flight deck automation are multifaceted and complex. The rapid introduction of advanced computer-based technology onto the flight deck of transport category aircraft has had considerable impact both on aircraft operations and on the flight crew. As part of NASA's responsibility to facilitate an active exchange of ideas and information among members of the aviation community, a NASA/FAA/Industry workshop devoted to flight deck automation, organized by the Aerospace Human Factors Research Division of NASA Ames Research Center. Participants were invited from industry and from government organizations responsible for design, certification, operation, and accident investigation of transport category, automated aircraft. The goal of the workshop was to clarify the implications of automation, both positive and negative. Workshop panels and working groups identified issues regarding the design, training, and procedural aspects of flight deck automation, as well as the crew's ability to interact and perform effectively with the new technology. The proceedings include the invited papers and the panel and working group reports, as well as the summary and conclusions of the conference.

  14. THz spectroscopy: An emerging technology for pharmaceutical development and pharmaceutical Process Analytical Technology (PAT) applications

    NASA Astrophysics Data System (ADS)

    Wu, Huiquan; Khan, Mansoor

    2012-08-01

    As an emerging technology, THz spectroscopy has gained increasing attention in the pharmaceutical area during the last decade. This attention is due to the fact that (1) it provides a promising alternative approach for in-depth understanding of both intermolecular interaction among pharmaceutical molecules and pharmaceutical product quality attributes; (2) it provides a promising alternative approach for enhanced process understanding of certain pharmaceutical manufacturing processes; and (3) the FDA pharmaceutical quality initiatives, most noticeably, the Process Analytical Technology (PAT) initiative. In this work, the current status and progress made so far on using THz spectroscopy for pharmaceutical development and pharmaceutical PAT applications are reviewed. In the spirit of demonstrating the utility of first principles modeling approach for addressing model validation challenge and reducing unnecessary model validation "burden" for facilitating THz pharmaceutical PAT applications, two scientific case studies based on published THz spectroscopy measurement results are created and discussed. Furthermore, other technical challenges and opportunities associated with adapting THz spectroscopy as a pharmaceutical PAT tool are highlighted.

  15. Photonic crystals: emerging biosensors and their promise for point-of-care applications.

    PubMed

    Inan, Hakan; Poyraz, Muhammet; Inci, Fatih; Lifson, Mark A; Baday, Murat; Cunningham, Brian T; Demirci, Utkan

    2017-01-23

    Biosensors are extensively employed for diagnosing a broad array of diseases and disorders in clinical settings worldwide. The implementation of biosensors at the point-of-care (POC), such as at primary clinics or the bedside, faces impediments because they may require highly trained personnel, have long assay times, large sizes, and high instrumental cost. Thus, there exists a need to develop inexpensive, reliable, user-friendly, and compact biosensing systems at the POC. Biosensors incorporated with photonic crystal (PC) structures hold promise to address many of the aforementioned challenges facing the development of new POC diagnostics. Currently, PC-based biosensors have been employed for detecting a variety of biotargets, such as cells, pathogens, proteins, antibodies, and nucleic acids, with high efficiency and selectivity. In this review, we provide a broad overview of PCs by explaining their structures, fabrication techniques, and sensing principles. Furthermore, we discuss recent applications of PC-based biosensors incorporated with emerging technologies, including telemedicine, flexible and wearable sensing, smart materials and metamaterials. Finally, we discuss current challenges associated with existing biosensors, and provide an outlook for PC-based biosensors and their promise at the POC.

  16. Application of near infrared reflectance (NIR) spectroscopy to identify potential PSE meat.

    PubMed

    Li, Xiao; Feng, Fang; Gao, Runze; Wang, Lu; Qian, Ye; Li, Chunbao; Zhou, Guanghong

    2016-07-01

    Pale, soft and exudative (PSE) meat is a quality problem that causes a large economic loss to the pork industry. In the present work, near infrared (NIR) quantification and identification methods were used to investigate the feasibility of differentiating potential PSE meat from normal meat. NIR quantification models were developed to estimate meat pH and colour attributes (L*, a*, b*). Promising results were reported for prediction of muscle pH (R(2) CV  = 70.10%, RPDCV = 1.83) and L* (R(2) CV  = 77.18%, RPDCV = 1.91), but it is still hard to promote to practical application at this level. The Factorisation Method applied to NIR spectra could differentiate potential PSE meat from normal meat at 3 h post-mortem. Correlation analysis showed significant relationship between NIR data and LF-NMR T2 components that were indicative of water distribution and mobility in muscle. PSE meat had unconventionally faster energy metabolism than normal meat, which caused greater water mobility. NIR spectra coupled with the Factorisation Method could be a promising technology to identify potential PSE meat. The difference in the intensity of H2 O absorbance peaks between PSE and normal meat might be the basis of this identification method. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.

  17. Tennessee Promise: A Response to Organizational Change

    ERIC Educational Resources Information Center

    Littlepage, Ben; Clark, Teresa; Wilson, Randal; Stout, Logan

    2018-01-01

    Community colleges in Tennessee, either directly or indirectly, experienced unprecedented change as a result of Tennessee Promise. The present study explored how student support service administrators at three community colleges responded to organizational change as a result of the Tennessee Promise legislation. Investigators selected community…

  18. Wearable technology for spine movement assessment: A systematic review.

    PubMed

    Papi, Enrica; Koh, Woon Senn; McGregor, Alison H

    2017-11-07

    Continuous monitoring of spine movement function could enhance our understanding of low back pain development. Wearable technologies have gained popularity as promising alternative to laboratory systems in allowing ambulatory movement analysis. This paper aims to review the state of art of current use of wearable technology to assess spine kinematics and kinetics. Four electronic databases and reference lists of relevant articles were searched to find studies employing wearable technologies to assess the spine in adults performing dynamic movements. Two reviewers independently identified relevant papers. Customised data extraction and quality appraisal form were developed to extrapolate key details and identify risk of biases of each study. Twenty-two articles were retrieved that met the inclusion criteria: 12 were deemed of medium quality (score 33.4-66.7%), and 10 of high quality (score >66.8%). The majority of articles (19/22) reported validation type studies. Only 6 reported data collection in real-life environments. Multiple sensors type were used: electrogoniometers (3/22), strain gauges based sensors (3/22), textile piezoresistive sensor (1/22) and accelerometers often used with gyroscopes and magnetometers (15/22). Two sensors units were mainly used and placing was commonly reported on the spine lumbar and sacral regions. The sensors were often wired to data transmitter/logger resulting in cumbersome systems. Outcomes were mostly reported relative to the lumbar segment and in the sagittal plane, including angles, range of motion, angular velocity, joint moments and forces. This review demonstrates the applicability of wearable technology to assess the spine, although this technique is still at an early stage of development. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  19. Understanding the Promise: A Typology of State and Local College Promise Programs

    ERIC Educational Resources Information Center

    Perna, Laura W.; Leigh, Elaine W.

    2018-01-01

    Over the past decade, but especially in the past few years, programs with a "promise" label have been advanced at the local, state, and federal levels. To advance understanding of the design, implementation, and impact of the many different versions of emerging programs, policymakers, practitioners, and researchers need an organizing…

  20. Gravitational-wave astronomy: delivering on the promises.

    PubMed

    Schutz, B F

    2018-05-28

    Now that LIGO and Virgo have begun to detect gravitational-wave events with regularity, the field of gravitational-wave astronomy is beginning to realize its promise. Binary black holes and, very recently, binary neutron stars have been observed, and we are already learning much from them. The future, with improved sensitivity, more detectors and detectors like LISA in different frequency bands, has even more promise to open a completely hidden side of the Universe to our exploration.This article is part of a discussion meeting issue 'The promises of gravitational-wave astronomy'. © 2018 The Author(s).

  1. Video on phone lines: technology and applications

    NASA Astrophysics Data System (ADS)

    Hsing, T. Russell

    1996-03-01

    Recent advances in communications signal processing and VLSI technology are fostering tremendous interest in transmitting high-speed digital data over ordinary telephone lines at bit rates substantially above the ISDN Basic Access rate (144 Kbit/s). Two new technologies, high-bit-rate digital subscriber lines and asymmetric digital subscriber lines promise transmission over most of the embedded loop plant at 1.544 Mbit/s and beyond. Stimulated by these research promises and rapid advances on video coding techniques and the standards activity, information networks around the globe are now exploring possible business opportunities of offering quality video services (such as distant learning, telemedicine, and telecommuting etc.) through this high-speed digital transport capability in the copper loop plant. Visual communications for residential customers have become more feasible than ever both technically and economically.

  2. Entry, Descent, and Landing Technology Concept Trade Study for Increasing Payload Mass to the Surface of Mars

    NASA Technical Reports Server (NTRS)

    Cruz, Juan R.; Cianciolo, Alicia D.; Powell, Richard W.; Simonsen, Lisa C.; Tolson, Robert H.

    2005-01-01

    A trade study was conducted that compared various entry, descent, and landing technologies and concepts for placing an 1,800 kg payload on the surface of Mars. The purpose of this trade study was to provide data, and make recommendations, that could be used in making decisions regarding which new technologies and concepts should be pursued. Five concepts were investigated, each using a different combination of new technologies: 1) a Baseline concept using the least new technologies, 2) Aerocapture and Entry from Orbit, 3) Inflatable Aeroshell, 4) Mid L/D Aeroshell-A (high ballistic coefficient), and 5) Mid L/D Aeroshell-B (low ballistic coefficient). All concepts were optimized to minimize entry mass subject to a common set of key requirements. These key requirements were: A) landing a payload mass of 1,800 kg, B) landing at an altitude 2.5 km above the MOLA areoid, C) landing with a descent rate of 2.5 m/s, and D) using a single launch vehicle available within the NASA Expendable Launch Vehicle Contract without resorting to in-space assembly. Additional constraints were implemented, some common to all concepts and others specific to the new technologies used. Among the findings of this study are the following observations. Concepts using blunt-body aeroshells (1, 2, and 3 above) had entry masses between 4,028 kg and 4,123 kg. Concepts using mid L/D aeroshells (4 and 5 above) were significantly heavier with entry masses of 5,292 kg (concept 4) and 4,812 kg (concept 5). This increased weight was mainly due to the aeroshell. Based on a comparison of the concepts it was recommended that: 1) re-qualified and/or improved TPS materials be developed, 2) large subsonic parachutes be qualified. Aerocapture was identified as a promising concept, but system issues beyond the scope of this study need to be investigated. Inflatable aeroshells were identified as a promising new technology, but they require additional technology maturation work. For the class of missions

  3. Technology for People, Not Disabilities: Ensuring Access and Inclusion

    ERIC Educational Resources Information Center

    Foley, Alan; Ferri, Beth A.

    2012-01-01

    The potential of technology to connect people and provide access to education, commerce, employment and entertainment has never been greater or more rapidly changing. Communication technologies and new media promise to "revolutionize our lives" by breaking down barriers and expanding access for disabled people. Yet, it is also true that technology…

  4. District Response to the Demonstration: The Practice of Technology.

    ERIC Educational Resources Information Center

    Fleming-McCormick, Treseen; And Others

    This paper reports on how technology is currently used in nine schools that educators view as "promising" exemplars of technology use. Four elementary, three middle and two high schools from Arizona, California and Nevada (three schools from each state) were examined. Extensive document review and telephone interviews were conducted in…

  5. Technology Tools to Support Reading in the Digital Age

    ERIC Educational Resources Information Center

    Biancarosa, Gina; Griffiths, Gina G.

    2012-01-01

    Advances in digital technologies are dramatically altering the texts and tools available to teachers and students. These technological advances have created excitement among many for their potential to be used as instructional tools for literacy education. Yet with the promise of these advances come issues that can exacerbate the literacy…

  6. Pharmaceutical technology management--profitable business avenue.

    PubMed

    Puthli, Shivanand P

    2010-01-01

    Growing research expenditure, regulatory framework and generic erosion have forced pharmaceutical companies globally to resort to pharmaceutical technology management (PTM). Indeed, the pharmaceutical industry has witnessed the impact of innovative drug delivery and device technologies and their influence on business. PTM has given a new business insight with greater profits and enhancement of product franchise. Promising breakthrough technologies have not been able to reach a commercial platform largely owing to lack of capital at the preliminary stages of the product development program. Intellectual property plays a considerable role in protecting innovative technologies. Joint ventures and strategic alliances also become important for commercializing a new technology. The synergy of PTM with options of in-licensing is expected to infuse newer opportunities to the pharmaceutical business.

  7. Results of advanced battery technology evaluations for electric vehicle applications

    NASA Astrophysics Data System (ADS)

    Deluca, W. H.; Gillie, K. R.; Kulaga, J. E.; Smaga, J. A.; Tummillo, A. F.; Webster, C. E.

    1992-10-01

    Advanced battery technology evaluations are performed under simulated electric-vehicle operating conditions at the Analysis and Diagnostic Laboratory (ADL) of Argonne National Laboratory. The ADL results provide insight into those factors that limit battery performance and life. The ADL facilities include a test laboratory to conduct battery experimental evaluations under simulated application conditions and a post-test analysis laboratory to determine, in a protected atmosphere if needed, component compositional changes and failure mechanisms. This paper summarizes the performance characterizations and life evaluations conducted during 1991-1992 on both single cells and multi-cell modules that encompass eight battery technologies (Na/S, Li/MS (M=metal), Ni/MH, Ni/Cd, Ni/Zn, Ni/Fe, Zn/Br, and Pb-acid). These evaluations were performed for the Department of Energy, Office of Transportation Technologies, Electric and Hybrid Propulsion Division, and the Electric Power Research Institute. The ADL provides a common basis for battery performance characterization and life evaluations with unbiased application of tests and analyses. The results help identify the most-promising R&D approaches for overcoming battery limitations, and provide battery users, developers, and program managers with a measure of the progress being made in battery R&D programs, a comparison of battery technologies, and basic data for modeling.

  8. Pervasive assistive technology for people with dementia: a UCD case

    PubMed Central

    Rønn-Andersen, Kristoffer V.H.; Bień, Paulina; Özkil, Ali Gürcan; Forchhammer, Birgitte Hysse; Maier, Anja M.

    2016-01-01

    Smart mobile and wearable technology offers exciting opportunities to support people with dementia (PwD). Its ubiquity and popularity could even benefit user adoption – a great challenge for assistive technology (AT) for PwD that calls for user-centred design (UCD) methods. This study describes a user-centred approach to developing and testing AT based on off-the-shelf pervasive technologies. A prototype is created by combining a smartphone, smartwatch and various applications to offer six support features. This is tested among five end-users (PwD) and their caregivers. Controlled usability testing was followed by field testing in a real-world context. Data is gathered from video recordings, interaction logs, system usability scale questionnaires, logbooks, application usage logs and interviews structured on the unified theory of acceptance and use of technology model. The data is analysed to evaluate usability, usefulness and user acceptance. Results show some promise for user adoption, but highlight challenges to be overcome, emphasising personalisation and familiarity as key considerations. The complete findings regarding usability issues, usefulness of support features and four identified adoption profiles are used to provide a set of recommendations for practitioners and further research. These contribute toward UCD practices for improved smart, pervasive AT for dementia. PMID:28008366

  9. Theoretical and experimental fundamentals of designing promising technological equipment to improve efficiency and environmental safety of highly viscous oil recovery from deep oil reservoirs

    NASA Astrophysics Data System (ADS)

    Moiseyev, V. A.; Nazarov, V. P.; Zhuravlev, V. Y.; Zhuykov, D. A.; Kubrikov, M. V.; Klokotov, Y. N.

    2016-12-01

    The development of new technological equipment for the implementation of highly effective methods of recovering highly viscous oil from deep reservoirs is an important scientific and technical challenge. Thermal recovery methods are promising approaches to solving the problem. It is necessary to carry out theoretical and experimental research aimed at developing oil-well tubing (OWT) with composite heatinsulating coatings on the basis of basalt and glass fibers. We used the method of finite element analysis in Nastran software, which implements complex scientific and engineering calculations, including the calculation of the stress-strain state of mechanical systems, the solution of problems of heat transfer, the study of nonlinear static, the dynamic transient analysis of frequency characteristics, etc. As a result, we obtained a mathematical model of thermal conductivity which describes the steady-state temperature and changes in the fibrous highly porous material with the heat loss by Stefan-Boltzmann's radiation. It has been performed for the first time using the method of computer modeling in Nastran software environments. The results give grounds for further implementation of the real design of the OWT when implementing thermal methods for increasing the rates of oil production and mitigating environmental impacts.

  10. 2016 National Algal Biofuels Technology Review Fact Sheet

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2016-06-01

    Algae-based biofuels and bioproducts offer great promise in contributing to the U.S. Department of Energy (DOE) Bioenergy Technologies Office’s (BETO’s) vision of a thriving and sustainable bioeconomy fueled by innovative technologies. The state of technology for producing algal biofuels continues to mature with ongoing investment by DOE and the private sector, but additional research, development, and demonstration (RD&D) is needed to achieve widespread deployment of affordable, scalable, and sustainable algal biofuels.

  11. Promise-based management: the essence of execution.

    PubMed

    Sull, Donald N; Spinosa, Charles

    2007-04-01

    Critical initiatives stall for a variety of reasons--employee disengagement, a lack of coordination between functions, complex organizational structures that obscure accountability, and so on. To overcome such obstacles, managers must fundamentally rethink how work gets done. Most of the challenges stem from broken or poorly crafted commitments. That's because every company is, at its heart, a dynamic network of promises made between employees and colleagues, customers, outsourcing partners, or other stakeholders. Executives can overcome many problems in the short-term and foster productive, reliable workforces for the long-term by practicing what the authors call "promise-based management," which involves cultivating and coordinating commitments in a systematic way. Good promises share five qualities: They are public, active, voluntary, explicit, and mission based. To develop and execute an effective promise, the "provider" and the "customer" in the deal should go through three phases of conversation. The first, achieving a meeting of minds, entails exploring the fundamental questions of coordinated effort: What do you mean? Do you understand what I mean? What should I do? What will you do? Who else should we talk to? In the next phase, making it happen, the provider executes on the promise. In the final phase, closing the loop, the customer publicly declares that the provider has either delivered the goods or failed to do so. Leaders must weave and manage their webs of promises with great care-encouraging iterative conversation and making sure commitments are fulfilled reliably. If they do, they can enhance coordination and cooperation among colleagues, build the organizational agility required to seize new business opportunities, and tap employees' entrepreneurial energies.

  12. Development of a Technology Transfer Score for Evaluating Research Proposals: Case Study of Demand Response Technologies in the Pacific Northwest

    NASA Astrophysics Data System (ADS)

    Estep, Judith

    Investment in Research and Development (R&D) is necessary for innovation, allowing an organization to maintain a competitive edge. The U.S. Federal Government invests billions of dollars, primarily in basic research technologies to help fill the pipeline for other organizations to take the technology into commercialization. However, it is not about just investing in innovation, it is about converting that research into application. A cursory review of the research proposal evaluation criteria suggests that there is little to no emphasis placed on the transfer of research results. This effort is motivated by a need to move research into application. One segment that is facing technology challenges is the energy sector. Historically, the electric grid has been stable and predictable; therefore, there were no immediate drivers to innovate. However, an aging infrastructure, integration of renewable energy, and aggressive energy efficiency targets are motivating the need for research and to put promising results into application. Many technologies exist or are in development but the rate at which they are being adopted is slow. The goal of this research is to develop a decision model that can be used to identify the technology transfer potential of a research proposal. An organization can use the model to select the proposals whose research outcomes are more likely to move into application. The model begins to close the chasm between research and application--otherwise known as the "valley of death". A comprehensive literature review was conducted to understand when the idea of technology application or transfer should begin. Next, the attributes that are necessary for successful technology transfer were identified. The emphasis of successful technology transfer occurs when there is a productive relationship between the researchers and the technology recipient. A hierarchical decision model, along with desirability curves, was used to understand the complexities of the

  13. Valuing technology: A qualitative interview study with physicians about insulin pump therapy for children with type 1 diabetes.

    PubMed

    Shulman, Rayzel; Miller, Fiona A; Daneman, Denis; Guttmann, Astrid

    2016-01-01

    Insulin pumps for children with type 1 diabetes have been broadly adopted despite equivocal evidence about comparative effectiveness. To understand why and inform policy related to public funding for new technologies, we explored how physicians interpret the value of pumps. We conducted open-ended, semi-structured interviews with 16 physicians from a pediatric diabetes network in Ontario, Canada, and analyzed the data using interpretive description. Respondents recognized that pumps fell short of expectations because they required hard work, as well as family and school support. Yet, pumps were valued for their status as new technologies and as a promising step in developing future technology. In addition, they were valued for their role within a therapeutic relationship, given the context of chronic childhood disease. These findings identify the types of beliefs that influence the adoption and diffusion of technologies. Some beliefs bear on hopes for new technology that may inappropriately hasten adoption, creating excess cost with little benefit. On the other hand, some beliefs identify potential benefits that are not captured in effectiveness studies, but may warrant consideration in resource allocation decisions. Still others suggest the need for remediation, such as those bearing on disparity in pump use by socioeconomic status. Understanding how technologies are valued can help stakeholders decide how to address such beliefs and expectations in funding decisions and implementation protocols. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  14. Antisense oligonucleotide technologies in drug discovery.

    PubMed

    Aboul-Fadl, Tarek

    2006-09-01

    The principle of antisense oligonucleotide (AS-OD) technologies is based on the specific inhibition of unwanted gene expression by blocking mRNA activity. It has long appeared to be an ideal strategy to leverage new genomic knowledge for drug discovery and development. In recent years, AS-OD technologies have been widely used as potent and promising tools for this purpose. There is a rapid increase in the number of antisense molecules progressing in clinical trials. AS-OD technologies provide a simple and efficient approach for drug discovery and development and are expected to become a reality in the near future. This editorial describes the established and emerging AS-OD technologies in drug discovery.

  15. Solar Energy: Its Technologies and Applications

    DOE R&D Accomplishments Database

    Auh, P. C.

    1978-06-01

    Solar heat, as a potential source of clean energy, is available to all of us. Extensive R and D efforts are being made to effectively utilize this renewable energy source. A variety of different technologies for utilizing solar energy have been proven to be technically feasible. Here, some of the most promising technologies and their applications are briefly described. These are: Solar Heating and Cooling of Buildings (SHACOB), Solar Thermal Energy Conversion (STC), Wind Energy Conversion (WECS), Bioconversion to Fuels (BCF), Ocean Thermal Energy Conversion (OTEC), and Photovoltaic Electric Power Systems (PEPS). Special emphasis is placed on the discussion of the SHACOB technologies, since the technologies are being expeditiously developed for the near commercialization.

  16. Artificial Intelligence Applications for Education: Promise, ...Promises.

    ERIC Educational Resources Information Center

    Adams, Dennis M.; Hamm, Mary

    1988-01-01

    Surveys the current status of artificial intelligence (AI) technology. Discusses intelligent tutoring systems, robotics, and applications for educators. Likens the status of AI at present to that of aviation in the very early 1900s. States that educators need to be involved in future debates concerning AI. (CW)

  17. Conceptual model for early health technology assessment of current and novel heart valve interventions

    PubMed Central

    Huygens, Simone A; Rutten-van Mölken, Maureen P M H; Bekkers, Jos A; Bogers, Ad J J C; Bouten, Carlijn V C; Chamuleau, Steven A J; de Jaegere, Peter P T; Kappetein, Arie Pieter; Kluin, Jolanda; van Mieghem, Nicolas M D A; Versteegh, Michel I M; Witsenburg, Maarten; Takkenberg, Johanna J M

    2016-01-01

    Objective The future promises many technological advances in the field of heart valve interventions, like tissue-engineered heart valves (TEHV). Prior to introduction in clinical practice, it is essential to perform early health technology assessment. We aim to develop a conceptual model (CM) that can be used to investigate the performance and costs requirements for TEHV to become cost-effective. Methods After scoping the decision problem, a workgroup developed the draft CM based on clinical guidelines. This model was compared with existing models for cost-effectiveness of heart valve interventions, identified by systematic literature search. Next, it was discussed with a Delphi panel of cardiothoracic surgeons, cardiologists and a biomedical scientist (n=10). Results The CM starts with the valve implantation. If patients survive the intervention, they can remain alive without complications, die from non-valve-related causes or experience a valve-related event. The events are separated in early and late events. After surviving an event, patients can experience another event or die due to non-valve-related causes. Predictors will include age, gender, NYHA class, left ventricular function and diabetes. Costs and quality adjusted life years are to be attached to health conditions to estimate long-term costs and health outcomes. Conclusions We developed a CM that will serve as foundation of a decision-analytic model that can estimate the potential cost-effectiveness of TEHV in early development stages. This supports developers in deciding about further development of TEHV and identifies promising interventions that may result in faster take-up in clinical practice by clinicians and reimbursement by payers. PMID:27843569

  18. Identifying and Integrating Relevant Educational/Instructional Technology (E/IT) for Culturally and Linguistically Diverse (CLD) Students with Disabilities in Urban Environments

    ERIC Educational Resources Information Center

    Brown, Monica R.

    2013-01-01

    The aim of this manuscript is to address the significant void in the literature related to technology integration for culturally and linguistically diverse (CLD) students with disabilities living in urban communities. Given that the vast majority of CLD students attend school within urban districts, the focus of this article is to (a) identify and…

  19. Novel treatment technologies for PFAS compounds: A critical review.

    PubMed

    Kucharzyk, Katarzyna H; Darlington, Ramona; Benotti, Mark; Deeb, Rula; Hawley, Elisabeth

    2017-12-15

    Perfluorinated compounds such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) have recently drawn great attention due to their wide distribution in aquatic environments. The understanding of the physicochemical properties and fate and transport of PFAs in groundwater is still limited. Preliminary studies indicate that these compounds can readily bioaccumulate and pose human and animal health concerns. Due to their physicochemical properties, PFOS and PFOA are water soluble, nonvolatile and persistent in the environment, which is a cause of concern related to their treatment with conventional remediation technologies. Extraction with inefficient carbon adsorption is one of the most common treatment technologies for remediation of PFOS- or PFOA-impacted groundwater. Several other innovative and promising technologies, including sonochemistry, bioremediation and photolysis, have been tested for their effectiveness in removal of perfluorinated compounds. This paper provides a baseline for understanding research needs to better develop treatment technologies for PFOA and PFOS in groundwater. Frontiers for improving the state of practice for PFOA and PFOS treatment include the development of more cost-effective ex situ treatment methods and the development and demonstration of promising in situ treatment technologies at the pilot and full scale. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. A review of radio frequency identification technology for the anatomic pathology or biorepository laboratory: Much promise, some progress, and more work needed.

    PubMed

    Lou, Jerry J; Andrechak, Gary; Riben, Michael; Yong, William H

    2011-01-01

    Patient safety initiatives throughout the anatomic laboratory and in biorepository laboratories have mandated increasing emphasis on the need for accurately identifying and tracking biospecimen assets throughout their production lifecycle and for archiving/retrieval purposes. However, increasing production volume along with complex workflow characteristics, reliance on manual production processes, and required asset movement to disparate destinations throughout asset lifecycles continue to challenge laboratory efforts. Radio Frequency Identification (RFID) technology, use of radio waves to communicate data between electronic tags attached to objects and a reader, shows significant potential to facilitate and overcome these hurdles. Advantages over traditional barcode labeling include readability without direct line-of-sight alignment to the reader, ability to read multiple tags simultaneously, higher data storage capacity, faster data transmission rate, and capacity to perform multiple read-writes of data to the tag. Most importantly, use of radio waves decreases the need to manually scan each asset, and at each step, identification or tracking event is needed. Temperature monitoring by on-board sensors and three-dimensional position tracking are additional potential benefits of using RFID technology. To date, barriers to implementation of RFID systems in the anatomic laboratory include increased associated costs of tags and readers, system software, data security concerns, lack of specific data standards for stored information, and potential for technological obsolescence during decades of specimen storage. Novel RFID production techniques and increased production capacity are projected to lower costs of some tags to a few cents each. Potentially, information security concerns can be addressed by techniques such as shielding, data encryption, and tag pseudonyms. Commitment by stakeholder groups to develop RFID tag data standards for anatomic pathology and

  1. A review of radio frequency identification technology for the anatomic pathology or biorepository laboratory: Much promise, some progress, and more work needed

    PubMed Central

    Lou, Jerry J.; Andrechak, Gary; Riben, Michael; Yong, William H.

    2011-01-01

    Patient safety initiatives throughout the anatomic laboratory and in biorepository laboratories have mandated increasing emphasis on the need for accurately identifying and tracking biospecimen assets throughout their production lifecycle and for archiving/retrieval purposes. However, increasing production volume along with complex workflow characteristics, reliance on manual production processes, and required asset movement to disparate destinations throughout asset lifecycles continue to challenge laboratory efforts. Radio Frequency Identification (RFID) technology, use of radio waves to communicate data between electronic tags attached to objects and a reader, shows significant potential to facilitate and overcome these hurdles. Advantages over traditional barcode labeling include readability without direct line-of-sight alignment to the reader, ability to read multiple tags simultaneously, higher data storage capacity, faster data transmission rate, and capacity to perform multiple read-writes of data to the tag. Most importantly, use of radio waves decreases the need to manually scan each asset, and at each step, identification or tracking event is needed. Temperature monitoring by on-board sensors and three-dimensional position tracking are additional potential benefits of using RFID technology. To date, barriers to implementation of RFID systems in the anatomic laboratory include increased associated costs of tags and readers, system software, data security concerns, lack of specific data standards for stored information, and potential for technological obsolescence during decades of specimen storage. Novel RFID production techniques and increased production capacity are projected to lower costs of some tags to a few cents each. Potentially, information security concerns can be addressed by techniques such as shielding, data encryption, and tag pseudonyms. Commitment by stakeholder groups to develop RFID tag data standards for anatomic pathology and

  2. Microfluidic chip-based technologies: emerging platforms for cancer diagnosis

    PubMed Central

    2013-01-01

    The development of early and personalized diagnostic protocols is considered the most promising avenue to decrease mortality from cancer and improve outcome. The emerging microfluidic-based analyzing platforms hold high promises to fulfill high-throughput and high-precision screening with reduced equipment cost and low analysis time, as compared to traditional bulky counterparts in bench-top laboratories. This article overviewed the potential applications of microfluidic technologies for detection and monitoring of cancer through nucleic acid and protein biomarker analysis. The implications of the technologies in cancer cytology that can provide functional personalized diagnosis were highlighted. Finally, the future niches for using microfluidic-based systems in tumor screening were briefly discussed. PMID:24070124

  3. Review of NASA In-Space Propulsion Technology Program Inflatable Decelerator Investments

    NASA Technical Reports Server (NTRS)

    Richardson, E. H.; Mnk, M. M.; James, B. F.; Moon, S. A.

    2005-01-01

    The NASA In-Space Propulsion Technology (ISPT) Program is managed by the NASA Headquarters Science Mission Directorate and is implemented by the Marshall Space Flight Center in Huntsville, Alabama. The ISPT objective is to fund development of promising in-space propulsion technologies that can decrease flight times, decrease cost, or increase delivered payload mass for future science missions. Before ISPT will invest in a technology, the Technology Readiness Level (TRL) of the concept must be estimated to be at TRL 3. A TRL 3 signifies that the technical community agrees that the feasibility of the concept has been proven through experiment or analysis. One of the highest priority technology investments for ISPT is Aerocapture. The aerocapture maneuver uses a planetary atmosphere to reduce or alter the speed of a vehicle allowing for quick, propellantless (or using very little propellant) orbit capture. The atmosphere is used as a brake, transferring the energy associated with the vehicle's high speed into thermal energy. The ISPT Aerocapture Technology Area (ATA) is currently investing in the development of advanced lightweight ablative thermal protection systems, high temperature composite structures, and heat-flux sensors for rigid aeroshells. The heritage of rigid aeroshells extends back to the Apollo era and this technology will most likely be used by the first generation aerocapture vehicle. As a second generation aerocapture technology, ISPT is investing in three inflatable aerodynamic decelerator concepts for planetary aerocapture. They are: trailing ballute (balloon-parachute), attached afterbody ballute, and an inflatable aeroshell. ISPT also leverages the NASA Small Business Innovative Research Program for additional inflatable decelerator technology development. In mid-2004 ISPT requested an independent review of the three inflatable decelerator technologies funded directly by ISPT to validate the TRL and to identify technology maturation concerns. An

  4. Review of NASA In-Space Propulsion Technology Program Inflatable Decelerator Investments

    NASA Technical Reports Server (NTRS)

    Richardson, Erin H.; Munk, Michelle M.; James, Bonnie F.; Moon, Steve A.

    2005-01-01

    The NASA In-Space Propulsion Technology (ISPT) Program is managed by the NASA Headquarters Science Mission Directorate and is implemented by the Marshall Space Flight Center in Huntsville, Alabama. The ISPT objective is to fund development of promising in- space propulsion technologies that can decrease flight times, decrease cost, or increase delivered payload mass for future science missions. Before ISPT will invest in a technology, the Technology Readiness Level (TRL) of the concept must be estimated to be at TRL 3. A TRL 3 signifies that the technical community agrees that the feasibility of the concept has been proven through experiment or analysis. One of the highest priority technology investments for ISPT is Aerocapture. The aerocapture maneuver uses a planetary atmosphere to reduce or alter the speed of a vehicle allowing for quick, propellantless (or using very little propellant) orbit capture. The atmosphere is used as a brake, transferring the energy associated with the vehicle s high speed into thermal energy. The ISPT Aerocapture Technology Area (ATA) is currently investing in the development of advanced lightweight ablative thermal protection systems, high temperature composite structures, and heat-flux sensors for rigid aeroshells. The heritage of rigid aeroshells extends back to the Apollo era and this technology will most likely be used by the first generation aerocapture vehicle. As a second generation aerocapture technology, ISPT is investing in three inflatable aerodynamic decelerator concepts for planetary aerocapture. They are: trailing ballute (balloon-parachute), attached afterbody ballute, and an inflatable aeroshell. ISPT also leverages the NASA Small Business Innovative Research Program for additional inflatable decelerator technology development. In mid-2004 ISPT requested an independent review of the three inflatable decelerator technologies funded directly by ISPT to validate the TRL and to identify technology maturation concerns. An

  5. Models for Building Knowledge in a Technology-Rich Setting: Teacher Education

    ERIC Educational Resources Information Center

    MacKinnon, Gregory R.; Aylward, M. Lynn

    2009-01-01

    Technology offers promising opportunities for creating new types of classroom learning environments. This paper describes three technology models used by teacher education interns: electronic portfolios, negotiative concept mapping, cognote-supported electronic discussions. As implemented in the current study, these models invoke graduated…

  6. Precision Voltage Referencing Techniques in MOS Technology.

    NASA Astrophysics Data System (ADS)

    Song, Bang-Sup

    With the increasing complexity of functions on a single MOS chip, precision analog cicuits implemented in the same technology are in great demand so as to be integrated together with digital circuits. The future development of MOS data acquisition systems will require precision on-chip MOS voltage references. This dissertation will probe two most promising configurations of on-chip voltage references both in NMOS and CMOS technologies. In NMOS, an ion-implantation effect on the temperature behavior of MOS devices is investigated to identify the fundamental limiting factors of a threshold voltage difference as an NMOS voltage source. For this kind of voltage reference, the temperature stability on the order of 20ppm/(DEGREES)C is achievable with a shallow single-threshold implant and a low-current, high-body bias operation. In CMOS, a monolithic prototype bandgap reference is designed, fabricated and tested which embodies a curvature compensation and exhibits a minimized sensitivity to the process parameter variation. Experimental results imply that an average temperature stability on the order of 10ppm/(DEGREES)C with a production spread of less than 10ppm/(DEGREES)C feasible over the commercial temperature range.

  7. Direct conversion technology

    NASA Technical Reports Server (NTRS)

    Massier, Paul F.; Bankston, C. P.; Williams, R.; Underwood, M.; Jeffries-Nakamura, B.; Fabris, G.

    1989-01-01

    The overall objective of the Direct Conversion Technology task is to develop an experimentally verified technology base for promising direct conversion systems that have potential application for energy conservation in the end-use sectors. This report contains progress of research on the Alkali Metal Thermal-to-Electric Converter (AMTEC), and on the Two-Phase Liquid-Metal Magnetohydrodynamic Electrical Generator (LMMHD) for the period January 1, 1989 through December 31, 1989. Research on these concepts was initiated during October 1987. Reports prepared on previous occasions contain discussions on the following other direct conversion concepts: thermoelectric, pyroelectric, thermionic, thermophotovoltaic, thermoacoustic, thermomagnetic, thermoelastic (nitinol heat engines); and also, more complete discussions of AMTEC and LMMHD systems.

  8. Object technology: A white paper

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jordan, S.R.; Arrowood, L.F.; Cain, W.D.

    1992-05-11

    Object-Oriented Technology (OOT), although not a new paradigm, has recently been prominently featured in the trade press and even general business publications. Indeed, the promises of object technology are alluring: the ability to handle complex design and engineering information through the full manufacturing production life cycle or to manipulate multimedia information, and the ability to improve programmer productivity in creating and maintaining high quality software. Groups at a number of the DOE facilities have been exploring the use of object technology for engineering, business, and other applications. In this white paper, the technology is explored thoroughly and compared with previousmore » means of developing software and storing databases of information. Several specific projects within the DOE Complex are described, and the state of the commercial marketplace is indicated.« less

  9. Environmental assessment of digestate treatment technologies using LCA methodology.

    PubMed

    Vázquez-Rowe, Ian; Golkowska, Katarzyna; Lebuf, Viooltje; Vaneeckhaute, Céline; Michels, Evi; Meers, Erik; Benetto, Enrico; Koster, Daniel

    2015-09-01

    The production of biogas from energy crops, organic waste and manure has augmented considerably the amounts of digestate available in Flanders. This has pushed authorities to steadily introduce legislative changes to promote its use as a fertilising agent. There is limited arable land in Flanders, which entails that digestate has to compete with animal manure to be spread. This forces many anaerobic digestion plants to further treat digestate in such a way that it can either be exported or the nitrogen be removed. Nevertheless, the environmental impact of these treatment options is still widely unknown, as well as the influence of these impacts on the sustainability of Flemish anaerobic digestion plants in comparison to other regions where spreading of raw digestate is allowed. Despite important economic aspects that must be considered, the use of Life Cycle Assessment (LCA) is suggested in this study to identify the environmental impacts of spreading digestate directly as compared to four different treatment technologies. Results suggest relevant environmental gains when the digestate mix is treated using the examined conversion technologies prior to spreading, although important trade-offs between impact categories were observed and discussed. The promising results of digestate conversion technologies suggest that further LCA analyses should be performed to delve into, for instance, the appropriateness to shift to nutrient recovery technologies rather than digestate conversion treatments. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Young children mostly keep, and expect others to keep, their promises.

    PubMed

    Kanngiesser, Patricia; Köymen, Bahar; Tomasello, Michael

    2017-07-01

    Promises are speech acts that create an obligation to do the promised action. In three studies, we investigated whether 3- and 5-year-olds (N=278) understand the normative implications of promising in prosocial interactions. In Study 1, children helped a partner who promised to share stickers. When the partner failed to uphold the promise, 3- and 5-year-olds protested and referred to promise norms. In Study 2, when children in this same age range were asked to promise to continue a cleaning task-and they agreed-they persisted longer on the task and mentioned their obligation more frequently than without such a promise. They also persisted longer after a promise than after a cleaning reminder (Study 3). In prosocial interactions, thus, young children feel a normative obligation to keep their promises and expect others to keep their promises as well. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Realizing the promises of marine biotechnology.

    PubMed

    Luiten, Esther E M; Akkerman, Ida; Koulman, Albert; Kamermans, Pauline; Reith, Hans; Barbosa, Maria J; Sipkema, Detmer; Wijffels, René H

    2003-07-01

    High-quality research in the field of marine biotechnology is one of the key-factors for successful innovation in exploiting the vast diversity of marine life. However, fascinating scientific research with promising results and claims on promising potential applications (e.g. for pharmaceuticals, nutritional supplements, (feed-)products for aquaculture and bioremediation solutions) is not the only factor to realise the commercial applications of marine biotechnology. What else is needed to exploit the promising potential of marine biotechnology and to create new industrial possibilities? In the study project 'Ocean Farming-Sustainable exploitation of marine organisms', we explore the possibilities of marine organisms to fulfill needs, such as safe and healthy food, industrial (raw) materials and renewable energy in a sustainable way. One of the three design groups is envisioning the future of strong land-based 'marine' market chains. Marine biotechnology is one of the foci of attention in this design group. This article provides a model of future-oriented thinking in which a variety of experts actively participate.

  12. Promising medications for cocaine dependence treatment.

    PubMed

    Somaini, Lorenzo; Donnini, Claudia; Raggi, Maria A; Amore, Mario; Ciccocioppo, Roberto; Saracino, Maria A; Kalluppi, Marsida; Malagoli, Marco; Gerra, Maria L; Gerra, Gilberto

    2011-05-01

    Cocaine dependence is characterized by compulsive drug seeking and high vulnerability to relapse. Overall, cocaine remains one of the most used illicit drugs in the world. Given the difficulty of achieving sustained recovery, pharmacotherapy of cocaine addiction remains one of the most important clinical challenges. Recent advances in neurobiology, brain imaging and clinical trials suggest that certain medications show promise in the treatment of cocaine addiction. The pharmacotherapeutic approaches for cocaine dependence include medications able to target specific subtypes of dopamine receptors, affect different neurotransmitter systems (i.e. noradrenergic, serotonergic, cholinergic, glutamatergic, GABAergic and opioidergic pathways), and modulate neurological processes. The systematic reviews concerning the pharmacological treatment of cocaine dependence appear to indicate controversial findings and inconclusive results. The aim of future studies should be to identify the effective medications matching the specific needs of patients with specific characteristics, abandoning the strategies extended to the entire population of cocaine dependent patients. In the present review we summarize the current pharmacotherapeutic approaches to the treatment of cocaine dependence with a focus on the new patents.

  13. Does technology really enhance nurse education?

    PubMed

    Goodchild, Tim

    2018-07-01

    Technology has clearly impacted upon our working lives, and the purpose of this paper is to offer a critical insight into the ubiquitous presence of technology in nurse education. This paper argues that technology enhanced learning is predicated on the promise of potential and purported transformation of teaching and learning. It suggests that there is a lack of critical engagement in the academic field of technology enhanced learning, and adds a critical voice to some of the emerging arguments in this area. There is also a lack of systematic evidence supporting the enhancement offered by technology, and yet the technology enhanced project continues to persist. The discourse surrounding technology enhanced learning has become so dominant, so pervasive, that those of us within it can no longer see alternatives. But there are alternatives, and this paper argues that we need to challenge the dominance of technology enhanced learning, and become aware of its contingent nature. Copyright © 2018 Elsevier Ltd. All rights reserved.

  14. The promise of a cognitive perspective on jury deliberation.

    PubMed

    Salerno, Jessica M; Diamond, Shari Seidman

    2010-04-01

    Despite much psychological research regarding jury decision making, surprisingly little is known about the deliberation process that gives rise to jury verdicts. We review classic jury decision-making research regarding the importance of deliberation and more recent research, investigating deliberation and hung juries, that challenges the view that deliberation does not have an important impact on verdicts. We advocate greater attention to potential cognitive processes during deliberation that might explain the transition between predeliberation preferences and a jury's ultimate verdict. We then review cognitive work in the group context generally, and the jury context specifically, illustrating the promise of a cognitive perspective on jury deliberation. Finally, we identify cognitive phenomena likely to be particularly valuable in illuminating deliberation behavior.

  15. Distress detection, location, and communications using advanced space technology. [satellite-borne synthetic aperture radar

    NASA Technical Reports Server (NTRS)

    Sivertson, W. E., Jr.

    1977-01-01

    This paper briefly introduces a concept for low-cost, global, day-night, all-weather disaster warning and assistance. Evolving, advanced space technology with passive radio frequency reflectors in conjunction with an imaging synthetic aperture radar is employed to detect, identify, locate, and provide passive communication with earth users in distress. This concept evolved from a broad NASA research on new global search and rescue techniques. Appropriate airborne radar test results from this research are reviewed and related to potential disaster applications. The analysis indicates the approach has promise for disaster communications relative to floods, droughts, earthquakes, volcanic eruptions, and severe storms.

  16. Technology Student Characteristics: Course Taking Patterns as a Pathway to STEM Disciplines

    ERIC Educational Resources Information Center

    Asunda, Paul A.; Kim, Eun Sook; Westberry, Richard

    2015-01-01

    Rising concern about America's ability to maintain its competitive position in the global economy has renewed interest in STEM education. The power and the promise of STEM education is based on the need for technological literacy. Technology education is a discipline devoted to the delivery of technological literacy for all. Nevertheless, a…

  17. First-principles engineering of charged defects for two-dimensional quantum technologies

    NASA Astrophysics Data System (ADS)

    Wu, Feng; Galatas, Andrew; Sundararaman, Ravishankar; Rocca, Dario; Ping, Yuan

    2017-12-01

    Charged defects in two-dimensional (2D) materials have emerging applications in quantum technologies such as quantum emitters and quantum computation. The advancement of these technologies requires a rational design of ideal defect centers, demanding reliable computation methods for the quantitatively accurate prediction of defect properties. We present an accurate, parameter-free, and efficient procedure to evaluate the quasiparticle defect states and thermodynamic charge transition levels of defects in 2D materials. Importantly, we solve critical issues that stem from the strongly anisotropic screening in 2D materials, that have so far precluded the accurate prediction of charge transition levels in these materials. Using this procedure, we investigate various defects in monolayer hexagonal boron nitride (h -BN ) for their charge transition levels, stable spin states, and optical excitations. We identify CBVN (nitrogen vacancy adjacent to carbon substitution of boron) to be the most promising defect candidate for scalable quantum bit and emitter applications.

  18. Quantifying nitrous oxide production pathways in wastewater treatment systems using isotope technology - A critical review.

    PubMed

    Duan, Haoran; Ye, Liu; Erler, Dirk; Ni, Bing-Jie; Yuan, Zhiguo

    2017-10-01

    Nitrous oxide (N 2 O) is an important greenhouse gas and an ozone-depleting substance which can be emitted from wastewater treatment systems (WWTS) causing significant environmental impacts. Understanding the N 2 O production pathways and their contribution to total emissions is the key to effective mitigation. Isotope technology is a promising method that has been applied to WWTS for quantifying the N 2 O production pathways. Within the scope of WWTS, this article reviews the current status of different isotope approaches, including both natural abundance and labelled isotope approaches, to N 2 O production pathways quantification. It identifies the limitations and potential problems with these approaches, as well as improvement opportunities. We conclude that, while the capabilities of isotope technology have been largely recognized, the quantification of N 2 O production pathways with isotope technology in WWTS require further improvement, particularly in relation to its accuracy and reliability. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. LEDs: DOE Programs Add Credibility to a Developing Technology

    ERIC Educational Resources Information Center

    Conbere, Susan

    2009-01-01

    LED (light-emitting diode) technology is moving fast, and with justification, some facility managers have viewed it with a wary eye. Some LEDs on the market do not perform as promised, and the technology is changing rapidly. But new developments from the U.S. Department of Energy (DOE) now make it easier for facility managers to find LEDs that…

  20. Wearable technology: using Google Glass as a teaching tool

    PubMed Central

    Knight, Hui Min; Gajendragadkar, Parag Ravindra; Bokhari, Awais

    2015-01-01

    Wearable technology holds great promise in revolutionising healthcare delivery. The benefits can also be seen in medical education and delivering healthcare in remote places. We report the use of Google Glass technology as a teaching tool in broadcasting a procedure onto a mobile phone as a viewer, replacing expensive and often cumbersome existing equipment. PMID:25969411

  1. Wearable technology: using Google Glass as a teaching tool.

    PubMed

    Knight, Hui Min; Gajendragadkar, Parag Ravindra; Bokhari, Awais

    2015-05-12

    Wearable technology holds great promise in revolutionising healthcare delivery. The benefits can also be seen in medical education and delivering healthcare in remote places. We report the use of Google Glass technology as a teaching tool in broadcasting a procedure onto a mobile phone as a viewer, replacing expensive and often cumbersome existing equipment. 2015 BMJ Publishing Group Ltd.

  2. Space and Industrial Brine Drying Technologies

    NASA Technical Reports Server (NTRS)

    Jones, Harry W.; Wisniewski, Richard S.; Flynn, Michael; Shaw, Hali

    2014-01-01

    This survey describes brine drying technologies that have been developed for use in space and industry. NASA has long considered developing a brine drying system for the International Space Station (ISS). Possible processes include conduction drying in many forms, spray drying, distillation, freezing and freeze drying, membrane filtration, and electrical processes. Commercial processes use similar technologies. Some proposed space systems combine several approaches. The current most promising candidates for use on the ISS use either conduction drying with membrane filtration or spray drying.

  3. Aviation technology applicable to developing regions

    NASA Technical Reports Server (NTRS)

    Zuk, John; Alton, Larry R.

    1988-01-01

    This paper is an analysis of aviation technologies useful for formulation of development plans to the year 2000 for emerging nations. The Caribbean Basin was used as a specific application. This development promises to be so explosive over the next 15 years as to be virtually unpredictable.

  4. Science and technology objective (STO) to develop tests for detecting microbial and chemical contaminants in food and water

    NASA Astrophysics Data System (ADS)

    Knechtges, Paul L.; Gargan, Thomas P., II; Burrows, William D.

    2002-02-01

    The assurance of safe food and water is paramount to the health and performance of the warfighter. Any technology to assess the chemical and microbial purity of food and water under field conditions must meet rigorous criteria: it must be readily portable, provide timely results (no more than 4 hours), have adequate sensitivity (1 cfu/100 mL for potable water), be compatible with military power sources, and be of complexity appropriate for operation by a Preventive Medicine Specialist. The nomination of an Army Science and Technology Objective (STO) leads to assessment of existing technologies and commercial products; identification of users, regulators and developers; definition of essential capabilities; and consideration of potential obstructions. The U.S. Army Center for Environmental Health Research has identified a number of technologies for detecting microbial contaminants in food and water and has pursued development of the more promising examples. This paper examines developmental risks in the context of the STO and offers some insight and strategies to manage them.

  5. The Promise of a College Scholarship Transforms a District

    ERIC Educational Resources Information Center

    Ritter, Gary W.; Ash, Jennifer

    2016-01-01

    Promise programs are place-based scholarships, generally tied to a city or school district, offering near-universal access to all living in the "place." While Promise programs share some characteristics with other scholarship programs, they're unique because they seek to change communities and schools. Underlying such promise programs is…

  6. Educating the Adolescent for Technological Changes: Some Implications for Teaching.

    ERIC Educational Resources Information Center

    Cheong, Lau Kam

    Generally concerned with how the schools can better educate the adolescent for adulthood, this paper briefly discusses the adolescent's need for work as a means of attaining adulthood, some promises and threats of technology, and effects of technological advances on society. Particular attention is given to four main effects having direct…

  7. Technology Transience and Distance Education in the Second Machine Age

    ERIC Educational Resources Information Center

    Swan, Karen

    2015-01-01

    In this article, the author explores how technological change is affecting most aspects of our society. In this vein, it is noted that even though education has historically been more resistant to technological change than other societal sectors, recent advances in distance education, specifically online learning, promise to radically disrupt…

  8. Preservice Teachers' Ability to Identify Technology Standards: Does Curriculum Matter?

    ERIC Educational Resources Information Center

    Lewis, Carrie L.

    2015-01-01

    Both preservice and in-service PK-12 teachers in the United States are expected to create a classroom environment that fosters the creation of digital citizens. However, it is unclear whether or not teacher education programs build this direct instruction, or any other method of introducing students to the International Society for Technology in…

  9. Payload software technology: Software technology development plan

    NASA Technical Reports Server (NTRS)

    1977-01-01

    Programmatic requirements for the advancement of software technology are identified for meeting the space flight requirements in the 1980 to 1990 time period. The development items are described, and software technology item derivation worksheets are presented along with the cost/time/priority assessments.

  10. Advanced Refrigerator/Freezer Technology Development. Technology Assessment

    NASA Technical Reports Server (NTRS)

    Gaseor, Thomas; Hunter, Rick; Hamill, Doris

    1996-01-01

    The NASA Lewis Research Center, through contract with Oceaneering Space Systems, is engaged in a project to develop advanced refrigerator/freezer (R/F) technologies for future Life and Biomedical Sciences space flight missions. The first phase of this project, a technology assessment, has been completed to identify the advanced R/F technologies needed and best suited to meet the requirements for the five R/F classifications specified by Life and Biomedical Science researchers. Additional objectives of the technology assessment were to rank those technologies based on benefit and risk, and to recommend technology development activities that can be accomplished within this project. This report presents the basis, the methodology, and results of the R/F technology assessment, along with technology development recommendations.

  11. Community health workers and mobile technology: a systematic review of the literature.

    PubMed

    Braun, Rebecca; Catalani, Caricia; Wimbush, Julian; Israelski, Dennis

    2013-01-01

    In low-resource settings, community health workers are frontline providers who shoulder the health service delivery burden. Increasingly, mobile technologies are developed, tested, and deployed with community health workers to facilitate tasks and improve outcomes. We reviewed the evidence for the use of mobile technology by community health workers to identify opportunities and challenges for strengthening health systems in resource-constrained settings. We conducted a systematic review of peer-reviewed literature from health, medical, social science, and engineering databases, using PRISMA guidelines. We identified a total of 25 unique full-text research articles on community health workers and their use of mobile technology for the delivery of health services. Community health workers have used mobile tools to advance a broad range of health aims throughout the globe, particularly maternal and child health, HIV/AIDS, and sexual and reproductive health. Most commonly, community health workers use mobile technology to collect field-based health data, receive alerts and reminders, facilitate health education sessions, and conduct person-to-person communication. Programmatic efforts to strengthen health service delivery focus on improving adherence to standards and guidelines, community education and training, and programmatic leadership and management practices. Those studies that evaluated program outcomes provided some evidence that mobile tools help community health workers to improve the quality of care provided, efficiency of services, and capacity for program monitoring. Evidence suggests mobile technology presents promising opportunities to improve the range and quality of services provided by community health workers. Small-scale efforts, pilot projects, and preliminary descriptive studies are increasing, and there is a trend toward using feasible and acceptable interventions that lead to positive program outcomes through operational improvements and

  12. Single-Lever Power Control for General Aviation Aircraft Promises Improved Efficiency and Simplified Pilot Controls

    NASA Technical Reports Server (NTRS)

    Musgrave, Jeffrey L.

    1997-01-01

    General aviation research is leading to major advances in internal combustion engine control systems for single-engine, single-pilot aircraft. These advances promise to increase engine performance and fuel efficiency while substantially reducing pilot workload and increasing flight safety. One such advance is a single-lever power control (SLPC) system, a welcome departure from older, less user-friendly, multilever engine control systems. The benefits of using single-lever power controls for general aviation aircraft are improved flight safety through advanced engine diagnostics, simplified powerplant operations, increased time between overhauls, and cost-effective technology (extends fuel burn and reduces overhaul costs). The single-lever concept has proven to be so effective in preliminary studies that general aviation manufacturers are making plans to retrofit current aircraft with the technology and are incorporating it in designs for future aircraft.

  13. Technology survey on video face tracking

    NASA Astrophysics Data System (ADS)

    Zhang, Tong; Gomes, Herman Martins

    2014-03-01

    With the pervasiveness of monitoring cameras installed in public areas, schools, hospitals, work places and homes, video analytics technologies for interpreting these video contents are becoming increasingly relevant to people's lives. Among such technologies, human face detection and tracking (and face identification in many cases) are particularly useful in various application scenarios. While plenty of research has been conducted on face tracking and many promising approaches have been proposed, there are still significant challenges in recognizing and tracking people in videos with uncontrolled capturing conditions, largely due to pose and illumination variations, as well as occlusions and cluttered background. It is especially complex to track and identify multiple people simultaneously in real time due to the large amount of computation involved. In this paper, we present a survey on literature and software that are published or developed during recent years on the face tracking topic. The survey covers the following topics: 1) mainstream and state-of-the-art face tracking methods, including features used to model the targets and metrics used for tracking; 2) face identification and face clustering from face sequences; and 3) software packages or demonstrations that are available for algorithm development or trial. A number of publically available databases for face tracking are also introduced.

  14. Digital optical tape: Technology and standardization issues

    NASA Technical Reports Server (NTRS)

    Podio, Fernando L.

    1996-01-01

    During the coming years, digital data storage technologies will continue an aggressive growth to satisfy the user's need for higher storage capacities, higher data transfer rates and long-term archival media properties. Digital optical tape is a promising technology to satisfy these user's needs. As any emerging data storage technology, the industry faces many technological and standardization challenges. The technological challenges are great, but feasible to overcome. Although it is too early to consider formal industry standards, the optical tape industry has decided to work together by initiating prestandardization efforts that may lead in the future to formal voluntary industry standards. This paper will discuss current industry optical tape drive developments and the types of standards that will be required for the technology. The status of current industry prestandardization efforts will also be discussed.

  15. Technology readiness levels for the new millennium program

    NASA Technical Reports Server (NTRS)

    Moynihan, P. I.; Minning, C. P.; Stocky, J. F.

    2003-01-01

    NASA's New Millennium Program (NMP) seeks to advance space exploration by providing an in-space validating mechanism to verify the maturity of promising advanced technologies that cannot be adequately validated with Earth-based testing alone. In meeting this objective, NMP uses NASA Technology Readiness Levels (TRL) as key indicators of technology advancement and assesses development progress against this generalized metric. By providing an opportunity for in-space validation, NMP can mature a suitable advanced technology from TRL 4 (component and/or breadboard validation in laboratory environment) to a TRL 7 (system prototype demonstrated in an Earth-based space environment). Spaceflight technology comprises a myriad of categories, types, and functions, and as each individual technology emerges, a consistent interpretation of its specific state of technological advancement relative to other technologies is problematic.

  16. Children and computers: new technology--old concerns.

    PubMed

    Wartella, E A; Jennings, N

    2000-01-01

    Computer technology has ushered in a new era of mass media, bringing with it great promise and great concerns about the effect on children's development and well-being. Although we tend to see these issues as being new, similar promises and concerns have accompanied each new wave of media technology throughout the past century: films in the early 1900s, radio in the 1920s, and television in the 1940s. With the introduction of each of these technologies, proponents touted the educational benefits for children, while opponents voiced fears about exposure to inappropriate commercial, sexual, and violent content. This article places current studies on children and computers in a historical context, noting the recurrent themes and patterns in media research during the twentieth century. Initial research concerning each innovation has tended to focus on issues of access and the amount of time children were spending with the new medium. As use of the technology became more prevalent, research shifted to issues related to content and its effects on children. Current research on children's use of computers is again following this pattern. But the increased level of interactivity now possible with computer games and with the communication features of the Internet has heightened both the promise of greatly enriched learning and the concerns related to increased risk of harm. As a result, research on the effects of exposure to various types of content has taken on a new sense of urgency. The authors conclude that to help inform and sustain the creation of more quality content for children, further research is needed on the effects of media on children, and new partnerships must be forged between industry, academia, and advocacy groups.

  17. Clinical manufacturing of CAR T cells: foundation of a promising therapy

    PubMed Central

    Wang, Xiuyan; Rivière, Isabelle

    2016-01-01

    The treatment of cancer patients with autologous T cells expressing a chimeric antigen receptor (CAR) is one of the most promising adoptive cellular therapy approaches. Reproducible manufacturing of high-quality, clinical-grade CAR-T cell products is a prerequisite for the wide application of this technology. Product quality needs to be built-in within every step of the manufacturing process. We summarize herein the requirements and logistics to be considered, as well as the state of the art manufacturing platforms available. CAR-T cell therapy may be on the verge of becoming standard of care for a few clinical indications. Yet, many challenges pertaining to manufacturing standardization and product characterization remain to be overcome in order to achieve broad usage and eventual commercialization of this therapeutic modality. PMID:27347557

  18. Maternity care and liability: least promising policy strategies for improvement.

    PubMed

    Sakala, Carol; Yang, Y Tony; Corry, Maureen P

    2013-01-01

    The present liability system is not serving well childbearing women and newborns, maternity care clinicians, or those who pay for maternity care. Examination of evidence about the impact of this system on maternity care led us to identify seven aims for a high-functioning liability system in this clinical context. Herein, we identify policy strategies that are unlikely to meet the proposed criteria and contribute to needed improvements. A companion paper considers more promising strategies. We considered whether 25 strategies that have been used or proposed for improvement have met or could meet the seven aims. We used a best available evidence approach and drew on more recent empirical legal studies and health services research about maternity care and liability, when available, and considered other studies when unavailable. Fifteen strategies seem to have little potential to improve liability matters in maternity care. Despite support for capping non-economic damages, a series of studies has found a modest impact at best on maternity care. Maternity-specific studies also do not lend support to tort reforms collectively and several other specific tort reforms. Some tort alternative and liability insurance reform strategies have narrow aims and are not policy priorities. Caps on non-economic damages and other tort reforms have narrow aims and have been marginally effective at best in the context of maternity care. Several other possible reforms similarly are not promising. Continued focus on these strategies is unlikely to result in the high-performing liability system that maternity care stakeholders need. Copyright © 2013 Jacobs Institute of Women's Health. Published by Elsevier Inc. All rights reserved.

  19. Discovery of novel drugs for promising targets.

    PubMed

    Martell, Robert E; Brooks, David G; Wang, Yan; Wilcoxen, Keith

    2013-09-01

    Once a promising drug target is identified, the steps to actually discover and optimize a drug are diverse and challenging. The goal of this study was to provide a road map to navigate drug discovery. Review general steps for drug discovery and provide illustrating references. A number of approaches are available to enhance and accelerate target identification and validation. Consideration of a variety of potential mechanisms of action of potential drugs can guide discovery efforts. The hit to lead stage may involve techniques such as high-throughput screening, fragment-based screening, and structure-based design, with informatics playing an ever-increasing role. Biologically relevant screening models are discussed, including cell lines, 3-dimensional culture, and in vivo screening. The process of enabling human studies for an investigational drug is also discussed. Drug discovery is a complex process that has significantly evolved in recent years. © 2013 Elsevier HS Journals, Inc. All rights reserved.

  20. Conservation and renewable energy technologies for transportation

    NASA Astrophysics Data System (ADS)

    1990-11-01

    The Office of Transportation Technologies (OTT) is charged with long-term, high-risk, and potentially high-payoff research and development of promising transportation technologies that are unlikely to be undertaken by the private sector alone. OTT activities are designed to develop an advanced technology base within the U.S. transportation industry for future manufacture of more energy-efficient, fuel-flexible, and environmentally sound transportation systems. OTT operations are focused on three areas: advanced automotive propulsion systems including gas turbines, low heat rejection diesel, and electric vehicle technologies; advanced materials development and tribology research; and research, development, demonstration, test, and evaluation (including field testing in fleet operations) of alternative fuels. Five papers describing the transportation technologies program have been indexed separately for inclusion on the data base.

  1. Technological Determinism in Educational Technology Research: Some Alternative Ways of Thinking about the Relationship between Learning and Technology

    ERIC Educational Resources Information Center

    Oliver, M.

    2011-01-01

    This paper argues that research on the educational uses of technology frequently overemphasizes the influence of technology. Research in the field is considered a form of critical perspective, and assumptions about technology are questioned. Technological determinism is introduced, and different positions on this concept are identified. These are…

  2. Technology, Privacy and the Democratic Process.

    ERIC Educational Resources Information Center

    Gandy, Oscar H., Jr.; Simmons, Charles E.

    Through a review of two accelerating trends in the technology of producing and distributing information and entertainment, this paper argues that the promises of "the information economy" and the "television of abundance" bring not the emancipation of diversity and access, but the rapid disintegration of an already weakened…

  3. Digital Games as Educational Technology: Promise and Challenges in the Use of Games to Teach

    ERIC Educational Resources Information Center

    Tobias, Sigmund; Fletcher, J. Dexter; Chen, Fei

    2015-01-01

    Digital games were reviewed as an emerging tool in educational technology. Factors such as instructional effectiveness, time on task, relationship to curricula, student socio-economic status, violence in games, and game mechanics were considered. Despite considerable variability among studies, larger overall effect sizes for the impact of games on…

  4. Nanotechnology: Its Promise and Challenges

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Colvin, Vicki

    2009-05-14

    Vicki Colvin of Rice University talks about how nanotechnology-enabled systems, with dimensions on the scale of a billionth of a meter, offer great promise for solving difficult social problems and creating enormous possibilities.

  5. The Delphi Technique in Identifying Learning Objectives for the Development of Science, Technology and Society Modules for Palestinian Ninth Grade Science Curriculum

    ERIC Educational Resources Information Center

    Abualrob, Marwan M. A.; Daniel, Esther Gnanamalar Sarojini

    2013-01-01

    This article outlines how learning objectives based upon science, technology and society (STS) elements for Palestinian ninth grade science textbooks were identified, which was part of a bigger study to establish an STS foundation in the ninth grade science curriculum in Palestine. First, an initial list of STS elements was determined. Second,…

  6. Teaching with Technology: North Carolina Agriculture Teachers' Knowledge Acquisition, Attitudes, and Identified Barriers

    ERIC Educational Resources Information Center

    Williams, Maegen R.; Warner, Wendy J.; Flowers, James L.; Croom, D. Barry

    2014-01-01

    In order for agricultural education teachers to adapt to an ever-changing educational environment, they must possess the skills necessary to integrate technology into their classrooms. The purpose of this study was to examine the factors that influence North Carolina agriculture teachers' ability to integrate educational technology. This study…

  7. Glaucomatous patterns in Frequency Doubling Technology (FDT) perimetry data identified by unsupervised machine learning classifiers.

    PubMed

    Bowd, Christopher; Weinreb, Robert N; Balasubramanian, Madhusudhanan; Lee, Intae; Jang, Giljin; Yousefi, Siamak; Zangwill, Linda M; Medeiros, Felipe A; Girkin, Christopher A; Liebmann, Jeffrey M; Goldbaum, Michael H

    2014-01-01

    The variational Bayesian independent component analysis-mixture model (VIM), an unsupervised machine-learning classifier, was used to automatically separate Matrix Frequency Doubling Technology (FDT) perimetry data into clusters of healthy and glaucomatous eyes, and to identify axes representing statistically independent patterns of defect in the glaucoma clusters. FDT measurements were obtained from 1,190 eyes with normal FDT results and 786 eyes with abnormal FDT results from the UCSD-based Diagnostic Innovations in Glaucoma Study (DIGS) and African Descent and Glaucoma Evaluation Study (ADAGES). For all eyes, VIM input was 52 threshold test points from the 24-2 test pattern, plus age. FDT mean deviation was -1.00 dB (S.D. = 2.80 dB) and -5.57 dB (S.D. = 5.09 dB) in FDT-normal eyes and FDT-abnormal eyes, respectively (p<0.001). VIM identified meaningful clusters of FDT data and positioned a set of statistically independent axes through the mean of each cluster. The optimal VIM model separated the FDT fields into 3 clusters. Cluster N contained primarily normal fields (1109/1190, specificity 93.1%) and clusters G1 and G2 combined, contained primarily abnormal fields (651/786, sensitivity 82.8%). For clusters G1 and G2 the optimal number of axes were 2 and 5, respectively. Patterns automatically generated along axes within the glaucoma clusters were similar to those known to be indicative of glaucoma. Fields located farther from the normal mean on each glaucoma axis showed increasing field defect severity. VIM successfully separated FDT fields from healthy and glaucoma eyes without a priori information about class membership, and identified familiar glaucomatous patterns of loss.

  8. Information Technologies, Health, and Globalization: Anyone Excluded?

    PubMed Central

    Parent, Florence; Parent, Marc

    2001-01-01

    Modern information technologies and worldwide communication through the Internet promise both universal access to information and the globalization of the medico-social network's modes of communication between doctors, laboratories, patients, and other players. The authors, specialists in public health and members of an association that aims to create opportunities for access to training in public health in developing countries, warn that the use of the term "globalization" ignores the reality of the "digital divide," that is, the fact that social inequalities may preclude the realization of this promise on a truly global scale. PMID:11720953

  9. Information technologies, health, and "globalization": anyone excluded?

    PubMed

    Parent, F; Coppieters, Y; Parent, M

    2001-01-01

    Modern information technologies and worldwide communication through the Internet promise both universal access to information and the globalization of the medico-social network s modes of communication between doctors, laboratories, patients, and other players. The authors, specialists in public health and members of an association that aims to create opportunities for access to training in public health in developing countries, warn that the use of the term "globalization" ignores the reality of the "digital divide," that is, the fact that social inequalities may preclude the realization of this promise on a truly global scale.

  10. Fiber Optic Communications Technology. A Status Report.

    ERIC Educational Resources Information Center

    Hull, Joseph A.

    Fiber optic communications (communications over very pure glass transmission channels of diameter comparable to a human hair) is an emerging technology which promises most improvements in communications capacity at reasonable cost. The fiber transmission system offers many desirable characteristics representing improvements over conventional…

  11. Promising technological innovations in cognitive training to treat eating-related behavior.

    PubMed

    Forman, Evan M; Goldstein, Stephanie P; Flack, Daniel; Evans, Brittney C; Manasse, Stephanie M; Dochat, Cara

    2018-05-01

    One potential reason for the suboptimal outcomes of treatments targeting appetitive behavior, such as eating and alcohol consumption, is that they do not target the implicit cognitive processes that may be driving these behaviors. Two groups of related neurocognitive processes that are robustly associated with dysregulated eating and drinking are attention bias (AB; selective attention to specific stimuli) and executive function (EF; a set of cognitive control processes such as inhibitory control, working memory, set shifting, that govern goal-directed behaviors). An increasing body of work suggests that EF and AB training programs improve regulation of appetitive behaviors, especially if trainings are frequent and sustained. However, several key challenges, such as adherence to the trainings in the long term, and overall potency of the training, remain. The current manuscript describes five technological innovations that have the potential to address difficulties related to the effectiveness and feasibility of EF and AB trainings: (1) deployment of training in the home, (2) training via smartphone, (3) gamification, (4) virtual reality, and (5) personalization. The drawbacks of these innovations, as well as areas for future research, are also discussed. The above-mentioned innovations are likely to be instrumental in the future empirical work to develop and evaluate effective EF and AB trainings for appetitive behaviors. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Aircraft System Analysis of Technology Benefits to Civil Transport Rotorcraft

    NASA Technical Reports Server (NTRS)

    Wilkerson, Joseph B.; Smith, Roger L.

    2008-01-01

    An aircraft systems analysis was conducted to evaluate the net benefits of advanced technologies on two conceptual civil transport rotorcraft, to quantify the potential of future civil rotorcraft to become operationally viable and economically competitive, with the ultimate goal of alleviating congestion in our airways, runways and terminals. These questions are three of many that must be resolved for the successful introduction of civil transport rotorcraft: 1) Can civil transport rotorcraft actually relieve current airport congestion and improve overall air traffic and passenger throughput at busy hub airports? What is that operational scenario? 2) Can advanced technology make future civil rotorcraft economically competitive in scheduled passenger transport? What are those enabling technologies? 3) What level of investment is necessary to mature the key enabling technologies? This study addresses the first two questions, and several others, by applying a systems analysis approach to a broad spectrum of potential advanced technologies at a conceptual level of design. The method was to identify those advanced technologies that showed the most promise and to quantify their benefits to the design, development, production, and operation of future civil rotorcraft. Adjustments are made to sizing data by subject matter experts to reflect the introduction of new technologies that offer improved performance, reduced weight, reduced maintenance, or reduced cost. This study used projected benefits from new, advanced technologies, generally based on research results, analysis, or small-scale test data. The technologies are identified, categorized and quantified in the report. The net benefit of selected advanced technologies is quantified for two civil transport rotorcraft concepts, a Single Main Rotor Compound (SMRC) helicopter designed for 250 ktas cruise airspeed and a Civil Tilt Rotor (CTR) designed for 350 ktas cruise airspeed. A baseline design of each concept was

  13. Nanocrystals Technology for Pharmaceutical Science.

    PubMed

    Cheng, Zhongyao; Lian, Yumei; Kamal, Zul; Ma, Xin; Chen, Jianjun; Zhou, Xinbo; Su, Jing; Qiu, Mingfeng

    2018-05-17

    Nanocrystals technology is a promising method for improving the dissolution rate and enhancing the bioavailability of poorly soluble drugs. In recent years, it has been developing rapidly and applied to drug research and engineering. Nanocrystal drugs can be formulated into various dosage forms. This review mainly focused on the nanocrystals technology and its application in pharmaceutical science. Firstly, different preparation methods of nanocrystal technology and the characterization of nanocrystal drugs are briefly described. Secondly, the application of nanocrystals technology in pharmaceutical science is mainly discussed followed by the introduction of sustained release formulations. Then, the scaling up process, marketed nanocrystal drug products and regulatory aspects about nanodrugs are summarized. Finally, the specific challenges and opportunities of nanocrystals technology for pharmaceutical science are summarized and discussed. This review will provide a comprehensive guide for scientists and engineers in the field of pharmaceutical science and biochemical engineering. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  14. Low-cost fabrication technologies for nanostructures: state-of-the-art and potential

    NASA Astrophysics Data System (ADS)

    Santos, A.; Deen, M. J.; Marsal, L. F.

    2015-01-01

    In the last decade, some low-cost nanofabrication technologies used in several disciplines of nanotechnology have demonstrated promising results in terms of versatility and scalability for producing innovative nanostructures. While conventional nanofabrication technologies such as photolithography are and will be an important part of nanofabrication, some low-cost nanofabrication technologies have demonstrated outstanding capabilities for large-scale production, providing high throughputs with acceptable resolution and broad versatility. Some of these nanotechnological approaches are reviewed in this article, providing information about the fundamentals, limitations and potential future developments towards nanofabrication processes capable of producing a broad range of nanostructures. Furthermore, in many cases, these low-cost nanofabrication approaches can be combined with traditional nanofabrication technologies. This combination is considered a promising way of generating innovative nanostructures suitable for a broad range of applications such as in opto-electronics, nano-electronics, photonics, sensing, biotechnology or medicine.

  15. Identifying, Licensing, and Commercializing Technology: An Entrepreneur's View

    NASA Astrophysics Data System (ADS)

    Appel, Kris

    2013-03-01

    A linguist by trade, Kris Appel left government service to pursue entrepreneurship. She knew she wanted to start a company, but she did not have a business idea. After researching various technologies available for commercialization, she began to focus on a prototype medical device at the University of Maryland Medical School, which had been developed to help stroke survivors recover their arm movement. The device was based upon emerging science into brain re-training, and was backed by very convincing clinical trials. Working closely with University researchers, she licensed the rights to the device, developed a commercial version, and launched it in 2009. Today the device is used around the globe, and has helped thousands of stroke and brain injury survivors improve their arm function and way of life. Kris will tell the story of the device, and how it got from idea to prototype to successful rehabilitation product.

  16. Webcasting: A New Technology for Training Special Educators in Rural Areas.

    ERIC Educational Resources Information Center

    Ludlow, Barbara L.; Duff, Michael C.

    This paper describes the use of webcasting technology in a personnel preparation program for rural special education practitioners. Emerging technologies offer promising solutions to the challenges of providing accessible and appropriate training to rural special educators. Web-based instruction is especially appropriate for on-the-job training of…

  17. Digital SPC switching technology: Foreign technology assessment

    NASA Astrophysics Data System (ADS)

    Fischman, Kurt; Jorstad, Norman D.

    1990-12-01

    This paper provides a foreign technology assessment of digital switching technology. Leading suppliers of digital switching technology are identified; although the United States holds a large part of the market, major companies in France, Sweden, Japan, the U.K., and Germany are also important. These countries, along with Belgium and Canada, are the most innovative and technically advanced. A listing is provided of transfers of digital switching technology to non-COCOM countries through licensing and joint ventures which reflects the widespread dissemination of this technology. Detailed technical specifications are provided for selected digital switching systems worldwide. The report concludes that considering the degree to which the technology is in place, that control of digital switching technology may not be feasible.

  18. Gene Editing of Human Hematopoietic Stem and Progenitor Cells: Promise and Potential Hurdles.

    PubMed

    Yu, Kyung-Rok; Natanson, Hannah; Dunbar, Cynthia E

    2016-10-01

    Hematopoietic stem and progenitor cells (HSPCs) have great therapeutic potential because of their ability to both self-renew and differentiate. It has been proposed that, given their unique properties, a small number of genetically modified HSPCs could accomplish lifelong, corrective reconstitution of the entire hematopoietic system in patients with various hematologic disorders. Scientists have demonstrated that gene addition therapies-targeted to HSPCs and using integrating retroviral vectors-possess clear clinical benefits in multiple diseases, among them immunodeficiencies, storage disorders, and hemoglobinopathies. Scientists attempting to develop clinically relevant gene therapy protocols have, however, encountered a number of unexpected hurdles because of their incomplete knowledge of target cells, genomic control, and gene transfer technologies. Targeted gene-editing technologies using engineered nucleases such as ZFN, TALEN, and/or CRISPR/Cas9 RGEN show great clinical promise, allowing for the site-specific correction of disease-causing mutations-a process with important applications in autosomal dominant or dominant-negative genetic disorders. The relative simplicity of the CRISPR/Cas9 system, in particular, has sparked an exponential increase in the scientific community's interest in and use of these gene-editing technologies. In this minireview, we discuss the specific applications of gene-editing technologies in human HSPCs, as informed by prior experience with gene addition strategies. HSPCs are desirable but challenging targets; the specific mechanisms these cells evolved to protect themselves from DNA damage render them potentially more susceptible to oncogenesis, especially given their ability to self-renew and their long-term proliferative potential. We further review scientists' experience with gene-editing technologies to date, focusing on strategies to move these techniques toward implementation in safe and effective clinical trials.

  19. When a desired home death does not occur: the consequences of broken promises.

    PubMed

    Topf, Lorrianne; Robinson, Carole A; Bottorff, Joan L

    2013-08-01

    Evidence shows that most people prefer to die at home; however, the majority of expected deaths occur away from home. Although home deaths require family caregiver (FCG) commitment and care, we understand very little about their experiences in this context. The study's aim was to gain a better understanding of the experiences of FCGs when circumstances prevented a desired home death for a family member with advanced cancer. An interpretive description approach was used. Data collection involved semistructured interviews. Field notes and reflective journaling aided interpretive and analytical processes. The study was conducted in western Canada and included 18 bereaved FCGs. FCGs were committed to the promises made to care for their family member at home until death. These promises were challenged by a lack of preparedness for caregiving, difficulty accessing professional support and information, and frustration with the inadequate help they received. The events that precipitated dying family members leaving their home for hospital or hospice were unexpected and often influenced by FCGs' lack of situation-specific knowledge and ability to cope with complex caregiving responsibilities. FCGs found it extremely challenging to reconcile with breaking their promise to care at home until death and many were unable to do so. FCGs' despair about not being able to keep their promise for a home death was related to complicated bereavement. Prospective studies of the experiences of FCGs who are aiming for home deaths are needed to identify both short- and long-term interventions to effectively support death at home.

  20. Genetic testing for inherited ocular disease: delivering on the promise at last?

    PubMed

    Gillespie, Rachel L; Hall, Georgina; Black, Graeme C

    2014-01-01

    Genetic testing is of increasing clinical utility for diagnosing inherited eye disease. Clarifying a clinical diagnosis is important for accurate estimation of prognosis, facilitating genetic counselling and management of families, and in the future will direct gene-specific therapeutic strategies. Often, precise diagnosis of genetic ophthalmic conditions is complicated by genetic heterogeneity, a difficulty that the so-called 'next-generation sequencing' technologies promise to overcome. Despite considerable counselling and ethical complexities, next-generation sequencing offers to revolutionize clinical practice. This will necessitate considerable adjustment to standard practice but has the power to deliver a personalized approach to genomic medicine for many more patients and enhance the potential for preventing vision loss. © 2013 Royal Australian and New Zealand College of Ophthalmologists.